PMID- 4345053
TI  - Effects of plasma lipoproteins from control and cholesterol-fed guinea pigs on
      red cell morphology and cholesterol content: an in vitro study.
AB  - When guinea pigs are fed cholesterol, the cholesterol content of their red cells
      increases progressively, a large number of cells become spurred, and a hemolytic
      anemia develops. Unesterified cholesterol is readily transferred from plasma,
      HDL, or LDL of cholesterol-fed, anemic guinea pigs to normal red cells in vitro.
      This transfer is reversible and is proportional to the concentration of
      unesterified cholesterol in the incubation medium. Red cells loaded in vitro with
      cholesterol develop spurs identical with those on red cells in the circulation of
      cholesterol-fed, anemic guinea pigs. Neither the cholesterol content nor the
      morphology of normal red cells is altered by incubation in control plasma or in
      concentrated control lipoproteins. Plasma infranates (d > 1.21 g/ml) of either
      group do not cause spurring of control red cells. We conclude: (a) that
      accumulation of cholesterol by guinea pig red cells in vitro requires an
      increased concentration of unesterified cholesterol in lipoprotein rather than an
      increased concentration of normal lipoproteins, and (b) that an increased
      cholesterol content in guinea pig red cell membranes is necessary for their
      abnormal morphology. The flux of cholesterol between cholesterol-loaded cells and
      plasma from cholesterol-fed guinea pigs is three times greater than that between
      control red cells and control plasma, and the fractional exchange rates are
      altered.

PMID- 4345054
TI  - Hypolipidemic effect of pregnancy in the rabbit.
AB  - New Zealand white rabbits showed large decreases in plasma cholesterol and
      phospholipid concentrations during the second half of pregnancy. All lipoproteins
      (very low density, low density, and high density) participated in the decrease.
      Very large decreases in plasma cholesterol concentrations were observed even when
      the animals were maintained on high cholesterol diets. Increases in plasma
      cholesterol concentrations, after the intravenous administration of Triton WR
      1339, were at least as great in pregnant as in nonpregnant animals. It is
      concluded that the decrease in plasma cholesterol concentrations is not the
      result of impaired plasma lipoprotein production.

PMID- 4345055
TI  - Characterization of subfractions of triglyceride-rich lipoproteins separated by
      gel chromatography from blood plasma of normolipemic and hyperlipemic humans.
AB  - As judged from measurements of the diameters of particles fixed with osmium
      tetroxide and shadowed with platinum, gel chromatography on 2% agarose has been
      shown to be an effective quantitative method for separating triglyceride-rich
      lipoproteins according to particle size. Particles in the size range of
      chylomicrons, uncontaminated by lipoproteins smaller than about 700 A or by other
      serum proteins, emerged in the void volume of the column, and very low density
      lipoproteins with diameters between 400 and 700 A were separated into fractions
      with average standard deviation of 71 A from the mean. Systematic comparison of
      the relationship between diameter and chemical composition of fractions obtained
      from subjects with various hyperlipoproteinemic disorders demonstrated a precise
      correlation consistent with a spherical model for these lipoproteins in which
      phospholipids, free cholesterol, and protein occupy a surface monolayer with an
      invariant thickness of 21.5 A surrounding a liquid core of triglycerides and
      cholesteryl esters. The chemical composition of very low density lipoproteins of
      given particle size in most recognized types of hyperlipemia was similar to that
      of normolipemic subjects, but particles in the size range of chylomicrons
      sometimes had higher contents of cholesteryl esters and free cholesterol. Results
      obtained in subjects with dysbetalipoproteinemia were consistent with the
      presence of three populations of particles. Two of these, with mean diameters of
      about 850 and 350 A, had unusually high cholesteryl ester content and reduced
      triglyceride content and may represent "remnants" of the metabolism of
      structurally normal chylomicrons and very low density lipoproteins, respectively.
      The third, a heterogeneous group with intermediate range of particle size and pre
      beta mobility, may represent a population of very low density lipoproteins with
      relatively normal composition.

PMID- 4345056
TI  - Rabbit muscle gangliosides.
AB  - Four ganglioside fractions were isolated from rabbit muscle: one hematoside and
      three hexosamine-containing species. They were analyzed for hexoses, hexosamine,
      sialic acid, fatty acids, and long-chain base content. The molar ratios of
      sphingosine-hexose-hexosamine-sialic acid were: for hematoside, 1:2:0:1; for the
      disialogangliosides, 1:3:1:2; and for trisialoganglioside, 1:3:1:3. The
      carbohydrates were studied by thin-layer and paper chromatography. The hexoses
      were glucose and galactose; the hexosamine was N-acetylgalactosamine and the
      sialic acid was N-acetylneuraminic acid. Fatty acids and long-chain bases were
      analyzed by gas-liquid chromatography. The fatty acid composition was similar in
      all of the four gangliosides. The most abundant fatty acids were 16:0 and 18:0,
      but significant amounts of 16:1, 18:1, 20:0, and 22:0 were also found. Hydroxy
      fatty acids were not detected. In all of the muscle gangliosides the main long
      chain bases were C(18)-sphingenine and C(20)-sphingenine. In hematoside there
      were also measurable amounts of C(18)-sphinganine and C(20)-sphinganine, whereas
      in the major gangliosides only traces of C(18)-sphinganine were detected.

PMID- 4345057
TI  - Comparison of two methods for determining human adipose cell size.
AB  - The mean cell sizes of specimens of human adipose tissue were determined on
      sectioned slices according to the method described by Sjostrom et al. (J. Lipid
      Res. 1971. 12: 521-530) and on adipocytes isolated after treatment of the tissue
      with collagenase. The average mean cell sizes from 11 biopsy specimens were 94.4
      and 94.0 micro m, respectively (r = 0.964; P(t(b)) < 0.001; y = 0.90x + 9.74),
      for the two methods. There was no indication of an increased rupture of isolated
      large human adipose cells. Thus, with precautions (freshly siliconized glassware
      and omitting the centrifugation of the isolated cells), the collagenase method
      may be used for metabolic as well as morphologic studies of human adipose tissue.

PMID- 4345059
TI  - [Significance of pyrophosphate excretion in primary hyperparathyroidism].

PMID- 4345058
TI  - Ribonucleic acid species of intracellular nucleocapsids and released virions of
      vesicular stomatitis virus.
AB  - Infection of chicken embryo cells with vesicular stomatitis (VS) virus resulted
      in variable production of three classes of intracellular viral ribonucleocapsids
      with sedimentation coefficients of approximately 140S, 110S, and 80S, as well as
      three corresponding classes of released virions designated B, LT, and T.
      Intracellular nucleocapsids of each class contained three proteins of which the
      major N protein was firmly bound, and the minor L and NS1 proteins were readily
      dissociated with 0.5 m NaCl. The ribonucleic acid (RNA) species extracted from B,
      LT, and T virions, and from corresponding intracellular nucleocapsids, contained
      RNA species with approximate molecular weights of 3.2 x 10(6), 2.0 x 10(6), and
      10(6), respectively, as determined by polyacrylamide gel electrophoresis. These
      values are roughly equivalent to sedimentation coefficients of 42S, 28S, and 23S
      for each of the virion and nucleocapsid RNA species. Cells infected at high
      multiplicity with undiluted passage VS virus gave rise primarily to virions and
      nucleocapsids containing 23S RNA, whereas cells productively infected with
      purified B virions produced predominantly B and LT virions and nucleocapsids. At
      late stages in the productive cycle of infection, more virions containing 42S RNA
      were produced, but the intracellular pool of nucleocapsids containing 28S and 23S
      RNA remained relatively constant. Additional studies by more refined techniques
      are required to test the hypothesis that nucleocapsids containing 28S and 23S RNA
      are precursors of the 42S RNA in infectious VS-B virions and that production of
      defective T and LT virions results from failure of ligation of the RNA
      precursors.

PMID- 4345060
TI  - [Hypoglycemic condition in insular tumors].

PMID- 4345061
TI  - [Asteroid bodies in aspergillosis].

PMID- 4345062
TI  - [Morphology of tissue forms of causative agents of visceral mycoses.
      Polysaccharide and protein histochemistry. 1].

PMID- 4345063
TI  - Prenatal diagnosis of G M1 -gangliosidosis.

PMID- 4345064
TI  - Prolonged oropharyngeal excretion of Epstein-Barr virus after infectious
      mononucleosis.

PMID- 4345065
TI  - Epstein-Barr virus and infectious mononucleosis.

PMID- 4345066
TI  - [Reactions of auditory cortex neurons to electrical stimulation of the internal
      geniculate body].

PMID- 4345067
TI  - Study on the effect of the 4-10 ACTH fraction on isolation-induced intermale
      fighting behaviour in the albino mouse.

PMID- 4345068
TI  - Accommodation function of the human eye.

PMID- 4345069
TI  - Biosynthesis of acetylcholine in nervous tissue.

PMID- 4345070
TI  - [Peripheral nerve injuries associated with traumatic lesions of bones and joints
      of the upper extremity].

PMID- 4345071
TI  - Pregnancy during convalescence from cytomegalovirus mononucleosis.

PMID- 4345072
TI  - [Clinical and morphopathological considerations on the recurrence and metastasis
      of cylindromas of the salivary glands].

PMID- 4345073
TI  - [Physiological and histological criteria for thyroid gland function following
      single or long-term administration of potassium perchlorate in adult mice (Mus
      musculus L.). II. Short-time experiments].

PMID- 4345074
TI  - Clinical study of pancuronium bromide as a neuromuscular blocking agent in
      anaesthesia.

PMID- 4345075
TI  - Effects of hyper- and hypofunctional states on the zonation of, and in vitro
      corticosterone production by the adrenocortical tissue in the domestic pigeon.

PMID- 4345076
TI  - Effect of ether stress on CRF-ACTH system of the domestic pigeon.

PMID- 4345077
TI  - [Palatal neoplasms of salivary origin (10 cases)].

PMID- 4345078
TI  - Vascular responses to cations, osmolality, and angiotensin in renal hypertensive
      dogs.

PMID- 4345079
TI  - Endogenous prostaglandins and osmotic water flow in the toad bladder.

PMID- 4345080
TI  - Hormone-induced growth of the adult lung.

PMID- 4345081
TI  - Dietary and drug treatment of primary hyperlipoproteinemia.

PMID- 4345082
TI  - Treatment of gram-negative bacillary meningitis in adults.

PMID- 4345083
TI  - Syringocystadenoma papilliferum. An electron microscopic study.

PMID- 4345084
TI  - [Electron microscopy study on the morphology of Paget cells].

PMID- 4345085
TI  - [Study on the neuro-endocrine system of the sheep. 3. Adrenal cortex function
      measurement by the Thorn test].

PMID- 4345086
TI  - Energy dependence of the half-reduction potential of iron-sulfur center 1 in the
      site I region of the respiratory chain in pigeon heart mitochondria.

PMID- 4345087
TI  - A protein kinase activity from rat cerebellum stimulated by guanosine-3':5'
      monophosphate.

PMID- 4345088
TI  - Interacting spin labels as probes of molecular separation within phospholipid
      bilayers.

PMID- 4345089
TI  - Three protein kinases from calf uterus. Subcellular distribution and physical
      properties.

PMID- 4345090
TI  - Involvement of cyclic 3',5'-adenosine monophosphate in replication of
      colicinogenic factor E 1  DNA.

PMID- 4345091
TI  - Sialic acid in prednisolone treated HeLa cells; suggested mechanism for elevated
      levels at the cell surface.

PMID- 4345092
TI  - A hypothesis for I-cell disease: defective hydrolases that do not enter
      lysosomes.

PMID- 4345093
TI  - Ultrastructural studies on the acute leukemic monoblast.

PMID- 4345094
TI  - [Familial glomangiomatosis].

PMID- 4345095
TI  - [Familial multiple glomangiomatosis. Phlebographic record].

PMID- 4345096
TI  - The effect of two diphosphonates on the resorption of mouse calvaria in vitro.

PMID- 4345097
TI  - Management of children with Wilms' tumor.

PMID- 4345098
TI  - Chemotherapy of ovarian cancer. New approaches to treatment.

PMID- 4345100
TI  - [Hearing disorders in chronic kidney insufficiency].

PMID- 4345099
TI  - Chemotherapeutic management of the hormone-secreting endocrine malignancies.

PMID- 4345101
TI  - Pharmacology of antagonists of angiotensin I and II.

PMID- 4345102
TI  - Renin in rats with spontaneous hypertension.

PMID- 4345103
TI  - Calcium current channels induced by catecholamines in chick embryonic hearts
      whose fast sodium channels are blocked by tetrodotoxin or elevated potassium.

PMID- 4345104
TI  - [The IgM latex test. A simple method for the rapid demonstration of infections in
      the neonatal period].

PMID- 4345105
TI  - Effect of allergenic extracts of house dust and bacterial vaccine on respiratory
      infections of mice.

PMID- 4345106
TI  - Evidence that the bone resorption-stimulating factor produced by mouse
      fibrosarcoma cells is prostaglandin E 2 . A new model for the hypercalcemia of
      cancer.
AB  - A transplantable mouse fibrosarcoma, HSDM(1), produces a potent bone resorption
      stimulating factor. The factor can be extracted from the tumor tissue and
      harvested from the medium of clonal strains of HSDM(1) tumor cells growing in
      monolayer culture. It has several chemical and biological properties of a
      prostaglandin. Using radioimmunoassay techniques, we have shown that HSDM(1)
      cells synthesize and secrete large quantities of prostaglandin E(2) (PGE(2)). The
      specific bone resorption-stimulating activity of the HSDM(1) factor extracted
      from the tumor is high and approximately equal to that of PGE(2) as measured in a
      bone tissue culture system in vitro. Indomethacin, a potent inhibitor of PGE(2)
      synthesis in HSDM(1) cells, also inhibits production by the cells of the bone
      resorption-stimulating factor, and has no detectable nonspecific effects on the
      bone culture assay system. Mice bearing the HSDM(1) tumor have higher levels of
      both calcium and PGE(2) in serum than control mice. We conclude that PGE(2) is
      the bone resorption-stimulating factor produced by HSDM(1) tumor cells, and that
      secretion of PGE(2) by the tumor in vivo accounts for the relative hypercalcemia
      observed in tumor-bearing animals. The HSDM(1) tumor cell system constitutes a
      new model for studying the pathogenesis of hypercalcemia associated with certain
      malignant tumors.

PMID- 4345107
TI  - Distribution of labeled lymph node cells in mice during the lymphocytosis induced
      by Bordetella pertussis.
AB  - The mechanism by which Bordetella pertussis organisms and their products induce
      lymphocytosis in mice was analyzed in terms of the localization of syngeneic Cr
      51-labeled lymph node cells. Labeled lymphoid cells incubated in vitro with the
      supernatant of B. pertussis cultures and then injected intravenously into normal
      recipients, or labeled cells injected into pertussis-treated recipients were
      unable to "home" to lymphoid organs but persisted for long periods in the blood.
      In animals "equipped" with a population of Cr-51-labeled lymphoid cells,
      administration of B. pertussis organisms or culture supernatant effected a shift
      of radioactivity from lymph nodes and spleen into the peripheral blood,
      coincident with the lymphocytosis. In in vitro experiments it was found that the
      active principle could bind to both erythrocytes and lymphocytes and could
      spontaneously elute from these cells onto labeled lymphocytes which were then
      unable to home efficiently. The data suggest that Bordetella pertussis-induced
      lymphocytosis involves a reversible attachment of the pertussis factor onto the
      surfaces of lymphocytes which prevents their recirculation to lymphoid organs.
      Recirculating lymphocytes are presumably affected as they emerge from lymphoid
      organs to enter the blood.

PMID- 4345109
TI  - Fine structure of the coelomocyte of adult Ascaris suum.

PMID- 4345108
TI  - Depressed cell-mediated immunity in patients with primary intracranial tumors.
      Characterization of a humoral immunosuppressive factor.
AB  - Tumor immunity in patients with primary intracranial tumors was assessed in
      relation to the general status of host immunocompetence. Lymphocyte sensitization
      to tumor-specific membrane antigens was demonstrated by the proliferative
      response of lymphocytes in the presence of autochthonous tumor cells.
      Paradoxically, one-half of the patients could not be sensitized to a primary
      antigen, dinitrochlorobenzene; existing delayed hypersensitivity was also
      depressed, as measured by skin tests and lymphocyte transformation in response to
      common antigens. A heat-stable factor in patients' sera blocked cell-mediated
      tumor immunity. In addition, these "enhancing" sera consistently suppressed the
      blastogenic response of autologous and homologous lymphocytes to
      phytohemagglutinin and to membrane antigens on allogeneic cells in the one-way
      mixed lymphocyte culture. When patients' leukocytes were washed and autologous
      plasma replaced with normal plasma, reactivity in the mixed lymphocyte culture
      increased to normal values. In vitro immunosuppressive activity in patients'
      plasma or sera correlated with depressed delayed hypersensitivity. After removal
      of the tumor, suppressor activity disappeared. IgG fractions of patient sera
      contained strong immunosuppressive activity. These data suggest that the
      suppressor factor may be an isoantibody elicited by the tumor that also binds to
      receptors on the lymphocyte membrane. In addition to specifically blocking cell
      mediated tumor immunity, enhancing sera may broadly depress host
      immunocompetence.

PMID- 4345110
TI  - Cytochrome C of Schistosoma mansoni.

PMID- 4345111
TI  - Calcium in the liver of mice infected with Trypanosoma cruzi.

PMID- 4345112
TI  - The stability of cortical phenotypes in continuously growing cultures of
      Tetrahymena pyriformis.

PMID- 4345113
TI  - C-type virus particles in phytohemagglutinin-stimulated lymphocyte cultures with
      reference to enzootic lymphatic leukosis in sheep.

PMID- 4345114
TI  - Sensitive quantitation of unlabelled SV 40 cRNA by competition hybridization with
      3 H-labelled in vitro cRNA.

PMID- 4345115
TI  - Ethanol metabolism and uric acid.

PMID- 4345116
TI  - Cardiac metastasis from a cystosarcoma phyllodes. Case report.

PMID- 4345117
TI  - Case records of the Massachusetts General Hospital. Weekly clinicopathological
      exercises. Case 4-1973.

PMID- 4345118
TI  - Responses of vestibular nuclear neurons to macular input.

PMID- 4345119
TI  - Transfer function of labyrinthine volleys through the vestibular nuclei.

PMID- 4345120
TI  - Semicircular canal inputs to vestibular nuclear neurons in the pigeon.

PMID- 4345121
TI  - Organization of the commissural connections: anatomy.

PMID- 4345122
TI  - Organization of the commissural connections: physiology.

PMID- 4345123
TI  - Vestibular influences on alpha motoneurons in the cervical and thoracic cord.

PMID- 4345124
TI  - Spinovestibular relations: anatomical and physiological aspects.

PMID- 4345125
TI  - MLF fibers originating from the lateral vestibular nucleus.

PMID- 4345126
TI  - Vestibulocerebellar input in the cat: anatomy.

PMID- 4345127
TI  - Vestibulocerebellar input in the frog: anatomy.

PMID- 4345128
TI  - Cerebellovestibular relations: anatomy.

PMID- 4345129
TI  - Cerebellar control of the vestibular neurones: physiology and pharmacology.

PMID- 4345130
TI  - Cerebellar control of the vestibular pathways to spinal motoneurons and primary
      afferents.

PMID- 4345131
TI  - Inhibitory and excitatory relay neurons for the vestibulo-ocular reflexes.

PMID- 4345132
TI  - Anatomy of the vestibuloreticular connections and possible 'ascending' vestibular
      pathways from the reticular formation.

PMID- 4345133
TI  - Reticular control of the vestibular nuclei: physiology and pharmacology.

PMID- 4345134
TI  - [Mineral constituents of enamel and dentin. A roentgenographic study].

PMID- 4345135
TI  - Usefulness of the dental age obtained by orthopantomography as an indicator of
      the physical age.

PMID- 4345136
TI  - [Functional morphology of the bacterial cell].

PMID- 4345137
TI  - A cocarcinogen in the eye-lens of fish?

PMID- 4345138
TI  - Mechanisms of hyperlipidaemias in different clinical conditions.

PMID- 4345139
TI  - [Heterologous mesodermal tumors of the uterus].

PMID- 4345140
TI  - Pigmented nodular synovitis: report of 11 lesions in non-articular locations.

PMID- 4345141
TI  - On the spectrophotometric determination of dissolved silica in natural waters.

PMID- 4345142
TI  - Independence of phospholipid and protein exchange between plasma lipoproteins in
      vivo and in vitro.

PMID- 4345143
TI  - Phospholipids and acyl groups of synaptosomal and myelin membranes isolated from
      the cerebral cortex of squirrel monkey (Saimiri sciureus).

PMID- 4345144
TI  - Subcellular distribution and kinetics of the acid cholesterol esterase in liver.

PMID- 4345145
TI  - Gangliosides of human, bovine and rabbit retina.

PMID- 4345146
TI  - Antitumor activity of vitamin A acid and fluorouracil used in combination on the
      skin tumor, keratoacanthoma.

PMID- 4345147
TI  - Individual versus group caging of mice with grafted tumors.

PMID- 4345148
TI  - Early lesions in cats inoculated with feline leukemia virus.

PMID- 4345149
TI  - The effect of cytosine arabinoside on virus production in various cells infected
      with herpes simplex virus types 1 and 2.

PMID- 4345150
TI  - Control of the adenylate charge in the Morris "minimal-deviation" hepatomas.

PMID- 4345151
TI  - Control of the adenylate charge in Novikoff ascites cells.

PMID- 4345152
TI  - Some physical and biological characteristics of the mouse mammary tumor virus.

PMID- 4345153
TI  - Chemical induction of subcutaneous tumors in BALB-c and Swiss mice infected with
      wild type C RNA viruses derived from BALB-c tissues.

PMID- 4345154
TI  - [Change in the concentration of free radicals during carcinogenesis caused by
      diethylnitrosamine].

PMID- 4345155
TI  - [Transglycosidase activity of myocardial NAD-glycohydrolase].

PMID- 4345156
TI  - [Change in the number of mitochondria in the process of loach oogenesis].

PMID- 4345157
TI  - [Change in the paramagnetic properties of rat liver due to the products of lipid
      oxidation].

PMID- 4345158
TI  - Insulin secretion during hemorrhagic shock in dogs.

PMID- 4345159
TI  - A new technique of counting ( 32 P) phospholipids in liquid scintillation counter
      without added scintillator.

PMID- 4345160
TI  - The electron spin resonance spectra of radical intermediates in the oxidation of
      ascorbic acid and related substances.

PMID- 4345161
TI  - Interactions of divalent metal ions with inorganic and nucleoside phosphates. II.
      Kinetics of magnesium(II) with HP 3 O 10  4- ,ATP, CTP, HP 2 O 7  3- , ADP, and
      CDP.

PMID- 4345162
TI  - Isolation and reactivation of the axostyle. Evidence for a dynein-like ATPase in
      the axostyle.
AB  - The contractile axostyle is a ribbon-shaped organelle present in certain species
      of flagellates found in the hindgut of wood eating insects. This organelle
      propagates an undulatory wave whose motion, like flagella and cilia, is related
      to microtubules. Unlike the axoneme of cilia and flagella, however, the axostyle
      is composed of singlet microtubules linked together in parallel rows. Axostyles
      were isolated from Cryptocercus gut protozoa with Triton X-100. Normal motility
      of the isolated axostyle could be restored with adenosine triphosphate (ATP); the
      specific conditions necessary for this reactivation were essentially identical
      with those reported for the reactivation of isolated flagella or whole sperm.
      ATPase activity of the isolated axostyle was comparable to the values reported
      for ciliary or flagellar axonemes. The axostyle was reasonably specific for ATP.
      Most of the proteins of the isolated axostyle comigrated with proteins of the
      ciliary axoneme on sodium dodecyl sulfate (SDS) polyacrylamide gels (i e.
      equivalent molecular weights). These included the following: the higher molecular
      weight component of dynein, tubulin, linkage protein (nexin), and various
      secondary proteins. Evidence for dynein in the axostyle is presented and a model
      proposed to explain how repeated propagated waves can be generated.

PMID- 4345163
TI  - Regulation of protein synthesis in the venom gland of viperid snakes.
AB  - Morphological changes in the venom gland of V. ammodytes were studied after the
      removal of the venom from the gland lumina (milking) It was found that the height
      of the secretory cells was changed during the secretory cycle. The patterns of
      the rough endoplasmic reticulum and of the Golgi complex were changed as well
      Milking induced an increased incorporation of [(14)C]amino acids into total and
      venom proteins In V ammodytes, during the first day after milking, 25% of the
      total counts in protein were precipitable by anti-venom serum, while at 8 days,
      80% of the proteins synthesized were venom proteins At this stage, the
      incorporation was 10- and 20-fold that of unmilked glands for total and venom
      proteins, respectively. Venom was accumulated (secreted) in the gland lumina of
      V. ammodytes at a relatively high rate up to 2 wk after milking and leveled off
      afterwards. Intact glands and gland slices of V ammodytes and V palaestinae,
      taken from snakes a few days after milking, incorporated [(14)C]amino acids into
      proteins in vitro at a rate higher than that of unmilked glands. The activity of
      two exportable enzymes (phosphodiesterase and benzoyl arginyl ethyl esterase) was
      assayed in gland homogenates of V. ammodytes. It was found that 2-3 wk after
      milking, the intracellular level of these enzymes was up to 2-fold that of
      unmilked glands.

PMID- 4345164
TI  - An improved cell fractionation procedure for the preparation of rat liver
      membrane-bound ribosomes.
AB  - A cell fractionation procedure is described which allows the preparation from rat
      liver of a rough microsome population containing almost 50% of the membrane-bound
      ribosomes of the tissue. The fraction is not contaminated with free ribosomes or
      smooth microsomes, and, by various other criteria, is suitable for studies of
      ribosome-membrane interaction.

PMID- 4345165
TI  - Single strand-containing replicating molecules of circular mitochondrial DNA.
AB  - Mitochondrial DNAs (mtDNAs) from Chang rat solid hepatomas and Novikoff rat
      ascites hepatomas were examined in the electron microscope after preparation by
      the aqueous and by the formamide protein monolayer techniques. MtDNAs from both
      tumors were found to include double-forked circular molecules with a form and
      size suggesting they were replicative intermediates. These molecules were of two
      classes. In molecules of one class, all three segments were apparently totally
      double stranded. Molecules of the second class were distinguished by the fact
      that one of the segments spanning the region between the forks in which
      replication had occurred (the daughter segments) was either totally single
      stranded, or contained a single-stranded region associated with one of the forks.
      Daughter segments of both totally double-stranded and single strand-containing
      replicating molecules varied in length from about 3 to about 80% of the circular
      contour length of the molecule. Similar classes of replicating molecules were
      found in mtDNA from regenerating rat liver and chick embryos, indicating them to
      be normal intermediates in the replication of mtDNA All of the mtDNAs examined
      included partially single-stranded simple (nonforked) circular molecules. A
      possible scheme for the replication of mtDNA is presented, based on the different
      molecular forms observed

PMID- 4345166
TI  - Adenine nucleotide-induced contraction of the inner mitochondrial membrane. I.
      General characterization.
AB  - The inner membranes of isolated bovine heart mitochondria undergo pronounced
      contraction upon being exposed to exogenous adenosine diphosphate (ADP),
      adenosine triphosphate (ATP), and certain other high-energy phosphate compounds.
      Contraction results in decrease of inner membrane expanse which in turn results
      in decrease of intracristal space and increase of mitochondrial optical density
      (OD). The magnitude of the OD change appears to be proportional to the degree of
      contraction Half-maximal contraction can be achieved with ADP or ATP at
      concentrations as low as about 0 3 microM. Atractyloside at concentrations as low
      as about 1.2 nmol/mg mitochondrial protein completely inhibits the contraction.
      It is concluded from these and other observations that inner membrane contraction
      occurs as a result of adenine nucleotide binding to the carrier involved in the
      exchange of adenine nucleotides across the inner mitochondrial membrane.

PMID- 4345167
TI  - Adenine nucleotide-induced contraction on the inner mitochondrial membrane. II.
      Effect of bongkrekic acid.
AB  - In bovine heart mitochondria bongkrekic acid at concentrations as low as about 4
      nmol/mg protein (a) completely inhibits phosphorylation of exogenous adenosine
      diphosphate (ADP) and dephosphorylation of exogenous adenosine triphosphate
      (ATP), (b) completely reverses atractyloside inhibition of inner membrane
      contraction induced by exogenous adenine nucleotides, and (c) decreases the
      amount of adenine nucleotide required to elicit maximal exogenous adenine
      nucleotide-induced inner membrane contraction to a level which appears to
      correspond closely with the concentration of contractile, exogenous adenine
      nucleotide binding sites Bongkrekic acid at concentrations greater than 4 nmol/mg
      protein induces inner membrane contraction which seems to depend on the presence
      of endogenous ADP and/or ATP. The findings appear to be consistent with the
      interpretations (a) that the inner mitochondrial membrane contains two types of
      contractile, adenine nucleotide binding sites, (b) that the two sites differ
      markedly with regard to adenine nucleotide affinity, (c) that the high affinity
      site is identical with the adenine nucleotide exchange carrier, (d) that the low
      affinity site is accessible exclusively to endogenous adenine nucleotides and is
      largely unoccupied in the absence of bongkrekic acid, and (e) that bongkrekic
      acid increases the affinity of both sites in proportion to the amount of the
      antibiotic bound to the inner membrane.

PMID- 4345168
TI  - Role of the cerebellum in the control of gastro-intestinal motility.

PMID- 4345169
TI  - Effects of p-chlorophenylalanine and a monoamine oxidase inhibitor on the 5
      hydroxytryptamine in the spinal cord and transection.

PMID- 4345170
TI  - Disorders of growth hormone and corticotropin regulation in patients with empty
      sella.

PMID- 4345171
TI  - Reovirus-induced aqueductal stenosis in hamsters. Phase contrast and electron
      microscopic studies.

PMID- 4345172
TI  - The induction of thrombosis in guinea pigs by a brain tumor.

PMID- 4345173
TI  - Storage of catecholamines in neuroblastoma and ganglioneuroma. A biochemical,
      immunologic, and morphologic study.

PMID- 4345174
TI  - [The effectiveness of radiation therapy in the combined treatment of hypophyseal
      adenomas].

PMID- 4345175
TI  - [Acute delirium tremens psychosis due to abstinence from alcohol].

PMID- 4345176
TI  - [Antisera of rabbits immunized against human low density lipoproteins (1,006
      1,063)].

PMID- 4345177
TI  - Neuropathic arthropathy (Charcot forefeet) in alcoholics.

PMID- 4345178
TI  - REM sleep and central monoamine oxidase inhibition.

PMID- 4345179
TI  - [Glucose-6-phosphatase in the liver and serum of rats loaded with x-ray
      irradiation and fasting].

PMID- 4345180
TI  - Observations on roentgen features of benign and malignant gastric ulcers.

PMID- 4345181
TI  - [Effect of nutrition on the development and function of the nervous system. 1].

PMID- 4345182
TI  - [Contrast roentgenography of the maxillary sinus in children without preliminary
      puncture (by the indirect administration method)].

PMID- 4345183
TI  - [The character of respiration in full-term newborn infants during diurnal sleep].

PMID- 4345184
TI  - [Clinico-morphologic forms of generalized cytomegaly].

PMID- 4345185
TI  - [The course of adenovirus infections in nursing mothers and in children during
      the 1st year of life].

PMID- 4345186
TI  - [Autophagy and glycogen distribution in the gastric epithelium of mice during
      differentiation].

PMID- 4345187
TI  - [Physiological and histological criteria of thyroid gland function following
      single or long-term administration of potassium perchlorate in adult mice (Mus
      musculus L.). I. Long-term experiments].

PMID- 4345188
TI  - Osteoclasts and their relationship to bone as studied by electron microscopy.

PMID- 4345189
TI  - Cytoplasmic vacuoles and bodies of the osteoclast. An electron microscope study.

PMID- 4345190
TI  - Tissue culture of rat adult decapsulated adrenal glands. A methodological,
      ultrastructural and morphometric investigation.

PMID- 4345191
TI  - The ultrastructure of oosorption in Locusta migratoria migratorioides.

PMID- 4345192
TI  - Isolation and classification of feline picornavirus and herpesvirus in Denmark.

PMID- 4345193
TI  - Theophylline-induced hypocalcemia in sheep.

PMID- 4345194
TI  - Juvenile nasopharyngeal angiofibroma: report of a case.

PMID- 4345195
TI  - [Mandibular resection. 2. On cancer surgery].

PMID- 4345196
TI  - Regional differentiation of the axon: a review with special reference to the
      concept of the multiplex neuron.

PMID- 4345197
TI  - Response patterns of single units in the olfactory bulb of the rat to odor.

PMID- 4345198
TI  - Repetitive firing in dorsal spinocerebellar tract neurones.

PMID- 4345199
TI  - [Pituitary apoplexy].

PMID- 4345200
TI  - Roentgenologic changes in hypothyroidism (a study of 40 cases).

PMID- 4345201
TI  - Pathogenesis of hypocalcemia in primary hypomagnesemia: normal end-organ
      responsiveness to parathyroid hormone, impaired parathyroid gland function.
AB  - Hypocalcemia is a frequent feature of hypomagnesemia in man and several other
      species. To elucidate the cause of this hypocalcemia, we have studied a child
      with primary hypomagnesemia and secondary hypocalcemia during magnesium
      supplementation when he was normomagnesemic and normocalcemic and after magnesium
      restriction for 16 days when he quickly became hypomagnesemic (0.5 meq/liter) and
      hypocalcemic (3.4 meq/liter) and had positive Chvostek's and Trousseau's signs.
      Whether in the normomagnesemic or hypomagnesemic state, intravenous bovine
      parathyroid extract (PTE) 8 U. S. P. U/kg promptly caused transient increases in
      the urinary phosphate excretion, renal phosphate clearance and cyclic AMP
      excretion. The magnitudes of these responses were similar in the two states, and
      similar to those observed in a hypoparathyroid patient. When the patient was
      hypomagnesemic and hypocalcemic, intramuscular PTE, 8 U/kg at 8-h intervals for
      four doses promptly caused hypercalcemia. The findings indicate that the end
      organs were responsive to parathyroid hormone. The concentrations of serum
      parathyroid hormone (PTH) were normal in the normomagnesemic state ranging from
      0.15 ng/ml to 0.40 ng/ml. Serum PTH did not increase in the hypomagnesemic state
      in spite of hypocalcemia. Indeed, PTH became unmeasurable in four consecutive
      samples at the end of the period of magnesium restriction. The concentrations of
      serum calcitonin remained unmeasurable (< 0.10 ng/ml) throughout the study,
      implying that excess calcitonin was not the cause of hypocalcemia in magnesium
      depletion. The findings in this study support our thesis that magnesium depletion
      causes impaired synthesis or secretion of parathyroid hormone. This impairment
      would account for the hypocalcemia observed in the hypomagnesemic state.

PMID- 4345202
TI  - Interchange of apolipoproteins between chylomicrons and high density lipoproteins
      during alimentary lipemia in man.
AB  - Apolipoproteins of the "C" group in human blood plasma, which contain the
      activator of the lipoprotein lipase-substrate interaction, were found to be
      transferred specifically from serum to phospholipid-stabilized fat emulsion.
      Content and distribution of apoprotein activator were measured in healthy men in
      the postabsorptive state and 4 h after ingestion of meals containing 100 g fat.
      Content of activator protein in whole serum did not change after ingestion of the
      fat-rich meals but that contained in triglyceride-rich lipoproteins of density
      (d) <1.006 approximately doubled whereas that of high density lipoproteins fell
      by half. The increased activator content of triglyceride-rich lipoproteins was
      virtually confined to chylomicrons and its concentration in chylomicron
      apoprotein was substantially greater than that in very low density lipoproteins.
      This difference could be ascribed largely to a higher content of C apoproteins in
      chylomicron protein since both the concentration of C apoproteins and of
      apoprotein activator were directly proportional to particle diameter while the
      pattern of fast-migrating C apoproteins in polyacrylamide gels was similar among
      chylomicrons and subfractions of very low density lipoproteins. Apparent
      concentration of activator protein was much greater in the high density
      lipoprotein subfraction of d 1.063-1.125 than in the subfraction of d 1.125-1.21.
      In the subfraction of d 1.063-1.125, the concentration of activator protein and
      of fast-migrating C apoproteins in polyacrylamide gels decreased after the fat
      rich meal. Concentration of phospholipids in this fraction increased gradually to
      a peak 43% above the basal value 6 h after the meal. The results obtained
      demonstrate that high density lipoproteins contribute certain functionally
      important polar constituents to chylomicrons during alimentary lipemia in man and
      suggest that they also receive surface constituents from chylomicrons during the
      course of their metabolism.

PMID- 4345203
TI  - Estrogen receptors in human breast cancer.
AB  - Specific quantitative techniques have been used to measure the cytoplasmic
      estradiol-binding protein (EBP) in human mammary carcinoma tissue specimens.
      Sucrose gradient centrifugation reveals EBP to sediment at 8S and 4S. Variable
      quantities of non-specific estradiol binding occurs in the 4S region of the
      sucrose gradient necessitating controls to insure specificity of the estradiol
      protein interaction. Using dextran-coated charcoal to separate bound from free
      estradiol Scatchard analysis finds the dissociation constant of the estradiol EBP
      interaction to be approximately 2.6x10(-10) M, indicative of the very high
      affinity of the ligand for the EBP. Quantitation of EBP sites in 64 primary and
      metastatic human breast tumors demonstrates a continuous spectrum of values from
      0 to 612 fmol per mg of cytoplasmic protein. Specific 8S binding in the sucrose
      gradient centrifugation was not detected in specimens containing less than 9.0
      fmol EBP per mg cytoplasmic protein. Since data from animal breast tumors and
      preliminary evidence from human breast tumors indicates an excellent correlation
      between the presence of abundant tumor EBP and endocrine-induced breast cancer
      regressions, precise quantitation of EBP in all human primary tumors may prove to
      be an excellent prognosticator of endocrine therapy in metastatic breast cancer.

PMID- 4345204
TI  - [The functional state of the adrenal cortex in congenital heart defects of the
      cyanotic type, before and after surgical treatment].

PMID- 4345205
TI  - [The pathogenesis of hypertension].

PMID- 4345206
TI  - Pseudopodia formation by secretory granules.

PMID- 4345207
TI  - Cyclic adenosine monophosphate-mediated stabilization of mouse neuroblastoma cell
      neuritis microtubules exposed to low temperature.

PMID- 4345208
TI  - Characteristics of two strains of avian sarcoma virus B77.

PMID- 4345209
TI  - Clonal analysis of RBI rat tumour cells producing chicken sarcoma virus.

PMID- 4345210
TI  - Different tumorigenicity of avian RNA sarcoma viruses for some mammalian species.

PMID- 4345211
TI  - On the presence of ribosome-like particles in avian myeloblastosis virions (AMV)
      and unusual ultrastructure of their nucleoid.

PMID- 4345212
TI  - Toward control of tumour and virus growth by helical RNA. I. Effect of poly I:C
      on tumour transplantation resistance in animals bearing tumours of viral and non
      viral origin.

PMID- 4345213
TI  - Inactivation of papovavirus SV 40 by cis-dichlorodiammine platinum(II).

PMID- 4345214
TI  - Polynucleotidases in mouse ascitic tumour cells.

PMID- 4345215
TI  - [Participation of paramyxovirus ribonucleoprotein in the formation of a
      transcription-translation complex].

PMID- 4345216
TI  - [Pathogenesis of respiratory viral infections].

PMID- 4345217
TI  - [Postvaccinal antiviral immunity and the role of tissue protective reactions in
      its mechanisms].

PMID- 4345218
TI  - Non beta cell tumors of the pancreas. A review with report of four cases.

PMID- 4345219
TI  - Effects of norepinephrine, angiotensin, dihydroergotamine, papaverine,
      isoproterenol, histamine, nicotinic acid, and xanthinol nicotinate on retinal
      oxygen tension in cats.

PMID- 4345220
TI  - [Thin-layer chromatographic separation of the constituents of hashish on pre
      coated silica gel sheets].

PMID- 4345221
TI  - [Blood plasma corticosterone content, glucocorticoid requirements of tissues and
      activity of respiratory enzymes in experimental tetanus].

PMID- 4345222
TI  - [Circadian rhythm of indices of lipid metabolism in healthy young subjects].

PMID- 4345223
TI  - [Histogenesis of human scirrhous carcinoma of the breast].

PMID- 4345224
TI  - [Histiocytosis with cells containing vermiform intracytoplasmic particles. 2nd
      case in an infant].

PMID- 4345225
TI  - [Poroepithelioma with lymph node metastasis].

PMID- 4345226
TI  - [Nevo-xantho-endothelioma in the adult].

PMID- 4345227
TI  - [Detection and preliminary study of an enzymatic system synthetizing alkanes in
      the supernatant of 105 000g Saccharomyces cerevisiae].

PMID- 4345228
TI  - Use of technetium 99m-labelled sodium pyrophosphate in skeletal scintigraphy.

PMID- 4345229
TI  - Enzyme activity patterns in gas gland tissue of the swimbladder of the cod (Gadus
      morrhua).

PMID- 4345230
TI  - The development of lipolytic sensitivity in the isolated fat cells of Gallus
      domesticus during the foetal and neonatal period.

PMID- 4345231
TI  - [Ultrastructural organization of cytochrome-C-phospholipid membranes following
      lipid removal and treatment with pronase].

PMID- 4345232
TI  - [Adenine nucleotides, NAD +  and NADH in skeletal muscles during intensive work
      and in rest periods].

PMID- 4345234
TI  - [Epitheliomas with altered stroma of the submaxillary gland (apropos of 9
      cases)].

PMID- 4345235
TI  - [2 tumors of the pneumogastric nerve].

PMID- 4345233
TI  - Enzyme markers: their linkage with proteins and use in immuno-histochemistry.

PMID- 4345236
TI  - Historical mixed tumor of the soft palate? (Or mixed tumor of the pharyngeal
      extension of the parotid gland).

PMID- 4345237
TI  - Potentiation of phenothiazines by  -methyltyrosine in treatment of chronic
      schizophrenia.

PMID- 4345238
TI  - Effect of methionine on liver lipid content and lipid metabolism of rats fed a
      protein-free diet.

PMID- 4345239
TI  - Cytomegalovirus infection in a newborn dizygous twin.

PMID- 4345240
TI  - Wilms' tumor in the newborn period.

PMID- 4345241
TI  - Discontinuous DNA replication in vitro. I. Two distinct size classes of
      intermediates.

PMID- 4345242
TI  - Mechanism of noradrenaline action in cat cerebral cortex.

PMID- 4345243
TI  - Size requirement of polyinosinic acid for DNA synthesis, viral resistance, and
      increased survival of leukaemic mice.

PMID- 4345244
TI  - Regulation of normal and leukaemic lymphocyte transformation and recirculation by
      sodium periodate oxidation and sodium borohydride reduction.

PMID- 4345245
TI  - [Late radiation-induced injuries of the skeletal system following radiotherapy
      for Wilms tumor].

PMID- 4345246
TI  - Photoreaction of FMN-tricine and its participation in photophosphorylation.

PMID- 4345247
TI  - Characterisation of staphylococci isolated from poultry.

PMID- 4345248
TI  - Properties of chick intestinal phytase.

PMID- 4345249
TI  - Intestinal alkaline phosphatase and phytase of chicks: effect of dietary
      magnesium, calcium, phosphorus and thyroactive casein.

PMID- 4345250
TI  - The effect of vitamin A on tumour development and regression in chickens infected
      with Marek's disease and Rous sarcoma virus.

PMID- 4345251
TI  - [Digestive epilepsy. 4 clinical cases].

PMID- 4345252
TI  - [Reputedly nephrotoxic antibiotic therapy during severe infections].

PMID- 4345253
TI  - [A case of hyponatremia caused by idiopathic hypervasopressinism. Psychosomatic
      mechanism?].

PMID- 4345254
TI  - [The occupational future of patients operated on for lumbar disk hernia].

PMID- 4345255
TI  - [Diagnostic difficulties in differentiating between Menetrier's disease and
      gastric cancer in a young woman].

PMID- 4345256
TI  - On the phosphorylation of Escherichia coli ribosomes. II. Reaction in cell-free
      system.

PMID- 4345257
TI  - Electron microscopic study on nuclear changes in multiple sclerosis brain
      biopsies.

PMID- 4345258
TI  - Electron microscopic studies of rabbit central and peripheral nervous system in
      experimental Borna disease.

PMID- 4345260
TI  - Age determination of swine foetuses.

PMID- 4345259
TI  - Effect of TOCP poisoning on the Pacinian corpuscles of slow loris.

PMID- 4345261
TI  - Recent contributions to the study of diabetic angiopathy and neuropathy.

PMID- 4345262
TI  - Aspergillosis complicating neoplastic disease.

PMID- 4345263
TI  - Low molecular weight glycogen as a cause of generalized glycogen storage disease.

PMID- 4345264
TI  - Unilateral total renal dysplasia in children.

PMID- 4345265
TI  - Disappearance of disseminated pancreatic carcinoma with combined chemotherapy.

PMID- 4345266
TI  - Angiotensin-receptor interaction: influence of pH on angiotensin inhibition by
      Phe 4 -Tyr 8 -angiotensin II in rat uterine smooth muscle.

PMID- 4345267
TI  - [Relationship between the pharmacological properties and the effect of
      acetylcholine on the urease activity].

PMID- 4345268
TI  - Factors affecting cholesterol esterase and cholesterol side-chain-cleavage
      activities in rat adrenal.

PMID- 4345269
TI  - The synthesis of beta corticotrophin-(1-24)-tetracosapeptide (synacthen) of high
      specific radioactivity.

PMID- 4345270
TI  - Observations on the fate of adrenocorticotrophin in isolated rat adrenal-cell
      suspensions and the separation of an enriched adrenocorticotrophin-sensitive
      steroidogenic cell fraction.

PMID- 4345271
TI  - Structure-activity relations for the nicotinamide-adenine-dinucleotide-linked 3
      hydroxysteroid oxidoreductase activity of cortisone reductase with special
      reference to the ring A-B junction and ring D.

PMID- 4345272
TI  - Structure-activity relations for the nicotinamide-adenine dinucleotide-linked
      20beta-hydroxysteroid oxidoreductase activity of cortisone reductase with special
      reference to ring B.

PMID- 4345273
TI  - Insulin release from mouse islets. Effect of glucose and hormones on adenylate
      cyclase.
AB  - The adenylate cyclase system of normal mouse islets was characterized. The pH
      optimum of the system was 7.6. The enzyme preparation contained particulate
      phosphodiesterase activity. This could be removed by treatment with 0.4% (v/v)
      Triton X-100 or inhibited by 8mm-theophylline in the presence of 2mm-cyclic AMP
      (adenosine 3':5'-cyclic monophosphate). ATP at 0.32mm produced one-half maximal
      enzyme activity. The enzyme was stimulated in the presence of F(-) and strongly
      inhibited by Ca(2+). The isolated enzyme retained hormonal sensitivity and was
      stimulated by glucagon, pancreozymin and secretin at physiological
      concentrations. Glucose at 17mm, 8mm and 2mm had no direct effect on the activity
      of the enzyme; neither did galactose at the same concentrations. Groups of islets
      incubated in 17mm- or 2mm-glucose for 5 or 15min and then homogenized and assayed
      for adenylate cyclase activity showed no differences in adenylate cyclase
      activity. The results suggest that the mechanism of glucose-mediated insulin
      release is not via the adenylate cyclase system. Hormones, however, could mediate
      insulin secretion via their effects on the adenylate cyclase system.

PMID- 4345274
TI  - Microbial metabolism of alkylbenzene sulphonates. Bacterial metabolism of
      undecylbenzene-p-sulphonate and dodecylbenzene-p-sulphonate.
AB  - 1. A study was made of the biodegradation of alkylbenzene sulphonate homologues,
      one of the major components of commercially marketed detergents. A Bacillus
      species was elected for growth on alkylbenzene sulphonate homologues as the sole
      source of carbon and sulphur. 2. The results from both whole-cell and cell-free
      systems indicated that the alkyl, aryl and sulphonate moieties of alkylbenzene
      sulphonate homologues were all further metabolized by the Bacillus species. 3.
      The alkyl side chain, after a presumed initial oxidation of the terminal methyl
      group, was subsequently oxidized by a beta-oxidation pathway. Three enzymes of
      the beta-oxidation pathway, i.e. acyl-CoA synthetase, acyl-CoA dehydrogenase and
      beta-hydroxyacyl-CoA dehydrogenase, were identified in cell-free extracts of the
      detergent-grown Bacillus species. The substrate specificity of acyl-CoA
      synthetase indicated activity towards several alkylbenzene sulphonate homologues.
      4. The sulphonate moiety was released as sulphite by a desulphonating enzyme.
      Some kinetic properties of this enzyme were determined. The sulphite was
      subsequently metabolized to either sulphate or adenosine 5'-sulphatophosphate.
      Two enzymes involved in sulphite metabolism, i.e. sulphite-cytochrome c reductase
      and adenosine 5'-sulphatophosphate-cytochrome c reductase were detected in cell
      free extracts of undecylbenzene-p-sulphonate-grown Bacillus species. 5. The
      combined results of continuous sampling programmes monitored by both t.l.c. and
      sulphite appearance in the growth medium indicated that desulphonation of the
      aromatic moiety was the likely first step in the overall biodegradation of
      several alkylbenzene sulphonate homologues. 6. The presence of p
      hydroxyphenylpropionate, p-hydroxybenzoate and 3,4-dihydroxybenzoate in cells
      after growth on several alkylbenzene sulphonate homologues containing an odd
      number of carbon atoms in the side chain was confirmed by g.l.c. and t.l.c.
      analysis. Cells grown on several homologues containing an even number of carbon
      atoms in the side chain were shown to contain p-hydroxyphenylacetate and 3,4
      dihydroxyphenylacetate. 7. The aromatic nucleus obtained from undecylbenzene-p
      sulphonate was further metabolized by an oxidation sequence involving an ;ortho
      cleavage' route. 8. An overall metabolic pathway for the biodegradation of
      various alkylbenzene sulphonate homologues by this Bacillus species is proposed.

PMID- 4345275
TI  - The role of histidine residues in glutamate dehydrogenase.
AB  - 1. Glutamate dehydrogenase was subject to rapid inactivation when irradiated in
      the presence of Rose Bengal or incubated in the presence of ethoxyformic
      anhydride. 2. Inactivation in the presence of Rose Bengal led to the photo
      oxidation of four histidine residues. Oxidation of three histidine residues had
      little effect on enzyme activity, but oxidation of the fourth residue led to the
      almost total loss of activity. 3. Acylation of glutamate dehydrogenase with
      ethoxyformic anhydride at pH6.1 led to the modification of three histidine
      residues with a corresponding loss of half the original activity. Acylation at
      pH7.5 led to the modification of two histidine residues and a total loss of
      enzyme activity. 4. One of the histidine residues undergoing reaction at pH6.1
      also undergoes reaction at pH7.5. 5. The presence of either glutamate or NAD(+)
      in the reaction mixtures at pH6.1 had no appreciable effect. At pH7.5 glutamate
      caused a marked decrease in both the degree of alkylation and degree of
      inactivation. NAD(+) had no effect on the degree of inactivation at pH7.5 but did
      modify the extent of acylation. 6. The normal response of the enzyme towards ADP
      was unaffected by acylation at pH6.1 or 7.5. 7. The normal response of the enzyme
      towards GTP was altered by treatment at both pH6.1 and 7.5.

PMID- 4345277
TI  - The location of adrenocorticotrophin receptors in the adrenal cortex.

PMID- 4345276
TI  - Studies on the light-dependent synthesis of inorganic pyrophosphate by
      Rhodospirillum rubrum chromatophores.
AB  - Characteristics of inorganic pyrophosphate synthesis from inorganic
      orthophosphate were examined in chromatophores of Rhodospirillum rubrum. The
      application of an ADP-glucose pyrophosphorylase-trapping system has shown in an
      unequivocal fashion that pyrophosphate is a product of a light-dependent reaction
      utilizing P(i) as the substrate. Only very limited pyrophosphate synthesis takes
      place in the dark. The rates of synthesis of both ATP and pyrophosphate were
      studied under conditions in which the membrane-bound adenosine triphosphatase and
      pyrophosphatase activities would normally make these substances unstable. The
      maximum rate of pyrophosphate synthesis was 25% of that for ATP synthesis, with
      maximum activation of pyrophosphate synthesis occurring at a lower light
      intensity than that required for ATP synthesis. As a result, at low light
      intensity the rate of pyrophosphate formation approached that of ATP. Maximal
      rates of synthesis of both pyrophosphate and ATP were attained only on the
      addition of an exogenous reducing agent. Conditions for optimum pyrophosphate
      synthesis required about one-half of the concentration of the reductant required
      for maximum ATP synthesis. Consistent with previous reports, oligomycin inhibited
      ATP synthesis, but had little influence on the rate of pyrophosphate synthesis.
      In membrane particles that retained pyrophosphatase activity but were treated to
      remove adenosine triphosphatase activity and the ability to photophosphorylate
      ADP, oligomycin stimulated light-dependent pyrophosphate synthesis by nearly
      250%. The influence of Mg(2+) concentration, pH and various inhibitors and
      uncouplers on pyrophosphate synthesis was studied. The results are discussed with
      respect to the mechanism and function of electron-transport-coupled energy
      conservation in R. rubrum chromatophores.

PMID- 4345278
TI  - The mode of adrenocorticotrophin action in stimulating steroidogenesis: the
      obligatory role of adenosine 3':5'-cyclic monophosphate and the involvement of
      rapidly-turning-over protein.

PMID- 4345279
TI  - The effect of adrenocorticotrophin in vivo on pregnenolone synthesis by adrenal
      mitochondria.

PMID- 4345280
TI  - The I-O-galactosylceramide fatty acid esters from hog stomach.

PMID- 4345281
TI  - Metabolism of prostaglandin F 1   in the guinea pig.

PMID- 4345282
TI  - The effects on cytochrome b-559HP and P546 of treatments that inhibit oxygen
      evolution by chloroplasts.

PMID- 4345283
TI  - Oxidative phosphorylation in yeast. X. Phosphorylation ability of mutants
      deficient in cytochromes a and b.

PMID- 4345284
TI  - Solubilization and purification of cytochrome   1  from Nitrosomonas.

PMID- 4345285
TI  - Conformation changes in cytochrome oxidase as studied by sedimentation
      difference.

PMID- 4345286
TI  - Biochemical and biophysical studies on cytochrome aa 3 . IX. Reaction of
      cytochrome aa 3  with hydrazine.

PMID- 4345287
TI  - Reduction and oxidation of longer-wavelength cytochrome b (b 566 ) in rat liver
      mitochondria under the influence of external oxidants.

PMID- 4345288
TI  - Some peculiarities of the steady-state kinetics of electron transfer in
      submitochondrial particles. A kinetic model based on the idea of activation on
      the respiratory chain induced by electron transfer.

PMID- 4345289
TI  - [Location of free valence in irradiated peptides containing histidine].

PMID- 4345290
TI  - [The effect of additions of a donor acceptor type on the photoactivity of
      chlorophyll in aqueous solutions of surface-active agents].

PMID- 4345291
TI  - [The kinetics of the development of the ESR signal with g-cp approximately equal
      to 2.03 in mitochondria treated with nitrite].

PMID- 4345292
TI  - [Effect of temperature on the ESR spectrum of an iminoxyl radical inserted into
      the active site of alpha-chymotrypsin].

PMID- 4345293
TI  - [Statistical evaluation of the magnitude of mouse liver ESR signals].

PMID- 4345294
TI  - Phenytoin treatment of thalamic pain.

PMID- 4345295
TI  - Studies on the mechanism of activation and deactivation of histidine
      decarboxylase.

PMID- 4345296
TI  - Anticholinergic action of aminophylline in isolated guinea-pig atria.

PMID- 4345297
TI  - Effects of a carbodiimide on neuromuscular transmission in frog.

PMID- 4345298
TI  - Mechanism of noradrenaline depression of cortical neurones: a species comparison.

PMID- 4345299
TI  - Lysosomal hydrolase alterations in the postphagocytic liver.

PMID- 4345300
TI  - [Late results of phimosis therapy in children].

PMID- 4345302
TI  - Demonstration of adenosin 3',5'-monophosphate dependent protein-phosphokinase in
      human platelets.

PMID- 4345303
TI  - Methods of anesthesia in nonhuman primates.

PMID- 4345301
TI  - [Relationship between the renin-angiotensin system and the autonomic nervous
      system].

PMID- 4345304
TI  - The pathology and pathogenesis of Bordetella bronchiseptica and Pasteurella
      pneumotropica infection in conventional and germfree rats.

PMID- 4345305
TI  - Intestinal helminths in inbred strains of mice.

PMID- 4345306
TI  - Pulmonary function measurements of large animals using the capacitance
      respirometer.

PMID- 4345307
TI  - An evaluation of the effects of various degrees of long-term confinement on adult
      beagle dogs.

PMID- 4345308
TI  - A diagnostic skin test for encephalitozoonosis (nosematosis) in rabbits.

PMID- 4345310
TI  - Induced aortic insufficiency in the canine. The tearing of a semilunar cusp for
      the study of experimental endocarditis.

PMID- 4345309
TI  - Dissociative anesthesia in dogs and primates: clinical evaluation of CI 744.

PMID- 4345311
TI  - A restraint system for squirrel monkeys.

PMID- 4345312
TI  - Induction of methoxyflurane anesthesia in the rabbit after ketamine hydrochloride
      and endotracheal intubation.

PMID- 4345313
TI  - Design for a chronic right ventricular catheter for dogs.

PMID- 4345314
TI  - Use of ketamine hybrochloride as an anesthetic in laboratory rabbits, rats, mice,
      and guinea pigs.

PMID- 4345315
TI  - A safe and versatile rabbit restrainer.

PMID- 4345316
TI  - Nymphal Porocephalus clavatus in the brain of a squirrel monkey, Saimiri
      sciureus.

PMID- 4345317
TI  - Traumatic pericarditis in a miniature pig.

PMID- 4345318
TI  - A method of bandaging queens to prevent nursing by newborn kittens until blood
      samples are collected.

PMID- 4345319
TI  - A versatile liquid diet for nonhuman primates.

PMID- 4345320
TI  - Scleral dermoid in a guinea pig.

PMID- 4345321
TI  - A simple apparatus for inducing and maintaining halothane anesthesia of the
      rabbit.

PMID- 4345322
TI  - A mixture for chemical restraint in the dog.

PMID- 4345323
TI  - [Intraperitoneal rupture of a malignant hepatoma with formation of a hematic
      pseudocyst. Subsegmental hepatic resection].

PMID- 4345324
TI  - [Endocrine paraneoplastic syndrome due to voluminous malignant nonchromaffin
      retroperitoneal paraganglioma].

PMID- 4345325
TI  - [Genetic counseling in dermatology].

PMID- 4345326
TI  - The effect of non-nicotinic drugs on the cat's adrenal medulla during block by
      nicotine.

PMID- 4345327
TI  - Effects of some inhibitors of phosphodiesterase on neuromuscular transmission.

PMID- 4345328
TI  - Calcium metabolism in tumors--its relationship with chromium complex
      accumulation. V. The interaction nucleic acid-calcium and the calcification of
      tumors.

PMID- 4345329
TI  - Erythrocyte lipids in childhood.

PMID- 4345330
TI  - Genetic control of susceptibility to the avian leukosis complex. I. The leukosis
      sarcoma virus group.

PMID- 4345331
TI  - Changes in fowl plasma  -lipoproteins caused by starvation.

PMID- 4345332
TI  - [Localization of components of the respiratory chain in submitochondrial
      particles].

PMID- 4345333
TI  - Cortisol, growth hormone response, and pain following tetracosactrin depot and
      ACTH gel.

PMID- 4345334
TI  - [Cytology of the cerebrospinal fluid in tumors of the nervous system].

PMID- 4345335
TI  - Independent effects of maternal age and birth order on the incidence of selected
      congenital malformations.

PMID- 4345336
TI  - The production of congenital malformations using tissue antisera. XI. Antisera to
      acellular visceral yolk sac.

PMID- 4345337
TI  - Malignant tumors arising de novo in immunosuppressed organ transplant recipients.

PMID- 4345338
TI  - [Supplementary method of identifying Brucella].

PMID- 4345339
TI  - [Time relationships between luteinising hormone discharge and endometrial
      morphology and histochemistry in the woman].

PMID- 4345340
TI  - Seroepidemiologic studies of herpesvirus type 2 and carcinoma of the cervix. 3.
      Houston, Texas.

PMID- 4345341
TI  - A method for aging the female Os pubis.

PMID- 4345342
TI  - Misapplication to females of the standard for aging the male Os pubis.

PMID- 4345343
TI  - The in vivo development of the hamster periodontium and implications for the
      chin's evolution.

PMID- 4345344
TI  - Lansing man: a half century later.

PMID- 4345345
TI  - Individualized predictive index for cancer of the rectum and colon.

PMID- 4345346
TI  - Tubular apocrine adenoma.

PMID- 4345347
TI  - Defects and deficiency of adenyl cyclase in psoriatic skin.

PMID- 4345348
TI  - Surface characteristics of SV40 transformed transplantable and non-transplantable
      mouse cells.

PMID- 4345349
TI  - Comparison of mammalian mitochondrial ribosomal ribonucleic acid from different
      species.
AB  - Mitochondrial ribosomal RNA species from mouse L cells, rat liver, rat hepatoma,
      hamster BHK-21 cells and human KB cells were examined by electrophoresis on
      polyacrylamide-agarose gels and sedimentation in sucrose density gradients. The
      S(E) (electrophoretic mobility) and S values of mitochondrial rRNA of all species
      were highly dependent on temperature and ionic strength of the medium; the S(E)
      values increased and the S values decreased with an increase in temperature at a
      low ionic strength. At an ionic strength of 0.3 at 23-25 degrees C or an ionic
      strength of 0.01 at 3-4 degrees C the S and S(E) values were almost the same
      being about 16.2-18.0 and 12.3-13.6 for human and mouse mitochondrial rRNA. The
      molecular weights under these conditions were calculated to be 3.8x10(5)
      4.3x10(5) and 5.9x10(5)-6.8x10(5), depending on the technique used. At 25 degrees
      C in buffers of low ionic strength mouse mitochondrial rRNA species had a lower
      electrophoretic mobility than those of human and hamster. Under these conditions
      the smaller mitochondrial rRNA species of hamster had a lower electrophoretic
      mobility than that of human but the larger component had an identical mobility.
      Mouse and rat mitochondrial rRNA species had identical electrophoretic
      mobilities. Complex differences between human and mouse mitochondrial rRNA
      species were observed on sedimentation in sucrose density gradients under various
      conditions of temperature and ionic strength. Mouse L-cell mitochondrial rRNA was
      eluted after cytoplasmic rRNA on a column of methylated albumin-kieselguhr.

PMID- 4345350
TI  - The utilization of iron and its complexes by mammalian mitochondria.
AB  - Sonicated mitochondria catalyse the reduction of ferric salts, and the subsequent
      incorporation of Fe(2+) into haem, when provided with a reducing substrate such
      as succinate or NADH. The rate of haem synthesis was low under aerobic conditions
      and, after a short lag period, accelerated once anaerobic conditions were
      achieved; it was insensitive to antimycin A. The lag period was decreased by
      preincubating the mitochondria with NADH and Fe(3+). Newly formed Fe(2+) was
      autoxidized rapidly and the consequent O(2) uptake was measured with an oxygen
      electrode to determine the rate of enzymic formation of Fe(2+) from FeCl(3); this
      reaction was rapid in sonicated mitochondria provided with NADH or succinate and
      was insensitive to antimycin A. The reaction was very slow in intact
      mitochondria, suggesting a permeability barrier to Fe(3+) ions. This system was
      used to test the permeability of the mitochondrial membrane to various iron
      complexes of biological importance. Of the compounds tested only ferrioxamine G
      appeared to penetrate readily and the iron of this complex was reduced when
      intact mitochondria were supplied with succinate or NADH-linked substrates. The
      reduction was insensitive to rotenone or antimycin A. Both ferrioxamine G and
      ferrioxamine B were, however, reduced by particles. The membrane fraction of
      sonicated mitochondria was necessary for the reduction. The rate of ferrioxamine
      B reduction by sonicated mitochondria was measured by a dual-wavelength
      spectrophotometric assay and was found to be stimulated in conditions where the
      Fe(2+) produced was utilized for haem synthesis. The addition of FeCl(3) to
      anaerobic particles caused an oxidation of cytochrome b when this region of the
      respiratory chain was isolated by treatment with rotenone and antimycin A. These
      results suggest that the reduction of ferric iron and its complexes occurs inside
      the inner mitochondrial membrane in proximity to ferrochelatase. Possible sites
      for this reduction are the flavoproteins, succinate and NADH dehydrogenase.

PMID- 4345351
TI  - The regulation of glyceride synthesis in isolated white-fat cells. The effects of
      palmitate and lipolytic agents.
AB  - 1. 0.5mm-Palmitate stimulated incorporation of [U-(14)C]glucose into glyceride
      glycerol and fatty acids in normal fat cells in a manner dependent upon the
      glucose concentration. 2. In the presence of insulin the incorporation of 5mm
      glucose into glyceride fatty acids was increased by concentrations of palmitate,
      adrenaline and 6-N-2'-O-dibutyryladenosine 3':5'-cyclic monophosphate up to
      0.5mm, 0.5mum and 0.5mm respectively. Higher concentrations of these agents
      produced progressive decreases in the rate of glucose incorporation into fatty
      acids. 3. The effects of palmitate and lipolytic agents upon the measured
      parameters of glucose utilization were similar, suggesting that the effects of
      lipolytic agents are mediated through increased concentrations of free fatty
      acids. 4. In fat cells from 24h-starved rats, maximal stimulation of glucose
      incorporation into fatty acids was achieved with 0.25mm-palmitate. Higher
      concentrations of palmitate were inhibitory. In fat cells from 72h-starved rats,
      palmitate only stimulated glucose incorporation into fatty acids at high
      concentrations of palmitate (1mm and above). 5. The ability of fat cells to
      incorporate glucose into glyceride glycerol in the presence of palmitate
      decreased with increasing periods of starvation. 6. It is suggested that low
      concentrations of free fatty acids stimulate fatty acid synthesis from glucose by
      increasing the utilization of ATP and cytoplasmic NADH for esterification of
      these free fatty acids. When esterification of free fatty acids does not keep
      pace with their provision, inhibition of fatty acid synthesis occurs. Provision
      of free fatty acids far in excess of the esterification capacity of the cells
      leads to uncoupling of oxidative phosphorylation and a secondary stimulation of
      fatty acid synthesis from glucose.

PMID- 4345352
TI  - Coproporphyrinogenase activities in extracts of Rhodopseudomonas spheroides and
      Chromatium strain D.
AB  - 1. The anaerobic coproporphyrinogenase activity in an extract of Rhodopseudomonas
      spheroides is inhibited by 1,10-phenanthroline, alphaalpha'-bipyridyl, flavins,
      2,4-dinitrophenol and 1,4-naphthaquinone. These compounds have no effect on the
      aerobic coproporphyrinogenase activity. 2. On removal of small-molecular-weight
      material from a crude extract, the anaerobic system becomes very unstable; it can
      be stabilized by adding succinate. Now nicotinamide nucleotides, in addition to
      Mg(2+), ATP and methionine, are required for protoporphyrin to be formed. 3. A
      mechanism for the anaerobic reaction is proposed, based on the cofactor
      requirements and the effect of inhibitors. 4. The enzyme responsible for aerobic
      activity has been partially purified and some of its properties are reported. 5.
      A crude extract of Chromatium strain D also exhibits coproporphyrinogenase
      activity under anaerobic conditions in the presence of S-adenosylmethionine or
      ATP plus methionine. The requirement for other cofactors is variable.

PMID- 4345353
TI  - The cytochromes of mitochondria from Tetrahymena pyriformis strain ST.
AB  - 1. Mitochondria of the obligately aerobic ciliate protozoon, Tetrahymena
      pyriformis strain ST, are unusual in that they possess a cytochrome oxidase
      system that does not react with reduced mammalian cytochrome c; the presence of
      cytochromes a(603)+a(3) is masked in the alpha-band region of spectra by the
      broad absorption band of cytochrome a(620). 2. Other haemoproteins present
      include cytochromes b(560), b(556), c(553) and c(549). 3. The reaction of reduced
      cytochrome a(3) with CO is reversed by flash photolysis, and in the presence of
      O(2) the subsequent oxidation of this cytochrome is followed by that of
      cytochrome a(603). 4. Cytochromes a(620) and b(560) also react with CO and with
      KCN; the latter cytochrome corresponds with that designated cytochrome o by other
      workers. 5. The contribution of cytochrome a(603) to difference spectra is
      revealed by making use of the fact that it does not react with KCN. 6. Cytochrome
      a(620) is unstable, and its alpha-absorption band is lost from spectra of
      mitochondria which have been aged or treated with ultrasound, detergents or
      organic solvents. 7. Possible pathways of electron transport via the several
      different terminal oxidases in Tetrahymena mitochondria are proposed.

PMID- 4345354
TI  - Glycine formation during growth of Pseudomonas AM1 on methanol and succinate.
AB  - 1. The mechanism of regeneration of glycine during the growth of Pseudomonas AM1
      on C(1) compounds has been investigated by brief incubation of bacterial
      suspensions with [2,3-(14)C(2)]succinate and observing the incorporation of
      radioactivity into various metabolites. 2. With the wild-type organism growing on
      methanol, radioactivity appeared rapidly in glycine and tricarboxylic acid-cycle
      intermediates, but there was a relatively slow labelling of serine and
      phosphorylated compounds. Serine became labelled predominantly in the C-2
      position. 3. The proportion of radioactivity incorporated into glycine at
      earliest times was greatly diminished when succinate-grown cells were used. 4.
      Radioactivity was also incorporated from [2,3-(14)C(2)]succinate into glycine and
      serine by methanol-grown mutant 20S, which lacks phosphoserine phosphohydrolase.
      Both the glycine and serine were labelled mainly in C-2. 5. The formation of
      predominantly [2-(14)C]serine from [2,3-(14)C(2)]succinate in wild-type
      Pseudomonas AM1, and of [2-(14)C]serine and [2-(14)C]glycine in the mutant
      lacking the phosphorylated pathway from succinate to serine, is taken as strong
      evidence for a mechanism of glycine regeneration involving cleavage of a C(4)
      skeleton between C-2 and C-3, rather than by a direct combination of two C(1)
      units derived from the growth substrate. 6. The cleavage mechanism is
      quantitatively more significant during growth on methanol than on succinate.

PMID- 4345355
TI  - A study of the cell surface of tumour, foetal and lymph-node cells by cell
      electrophoresis after antibody and enzymic treatment.
AB  - 1. Rabbit anti-(rat foetal liver) serum, absorbed with adult rat liver cells,
      decreased the electrophoretic mobility of foetal liver cells by 51% and rat
      hepatoma cells by 45%, indicating the presence of a foetal-type antigen on the
      hepatoma cell membrane. 2. The chemical nature of the surface antigen was
      investigated. Incubation with neuraminidase had no effect on adult liver cells
      but decreased the electrophoretic mobility of foetal liver cells by 51% and of
      hepatoma cells by 34%; the effect of antiserum was decreased to one-fifth. 3.
      Sialic acid, or the supernatant from neuraminidase-treated cells, partially
      blocked the decrease in electrophoretic mobility induced by antiserum. 4. The pH
      electrophoretic mobility curves of hepatoma cells treated with antisera were
      consistent with a sialic acidcontaining antigen on the surface of the tumour
      cells. 5. Treatment with ribonuclease did not decrease the electrophoretic
      mobility of adult-liver cells, but decreased that of the foetal liver cells by
      17% and hepatoma cells by 29%. 6. In parallel studies made with mouse BP8 ascites
      tumour cells ribonuclease decreased the electrophoretic mobility by 39%, that of
      normal mouse lymph-node cells by 4.8% and allergized mouse lymph-node cells by
      13.3%. 7. Trypsin treatment also decreased the electrophoretic mobility of
      hepatoma cells by 22%.

PMID- 4345356
TI  - Evaluation of the rate-limiting steps in the pathway of glucose metabolism in
      kidney cortex of normal, diabetic, cortisone-treated and growth hormone-treated
      rats.
AB  - 1. The activities of gluconeogenic and glycolytic enzymes and the concentrations
      of citrate, ammonia, amino acids, glycogen, glucose 6-phosphate, acetyl-CoA,
      lactate and pyruvate were measured in kidney cortex of normal, diabetic,
      cortisone-treated and growth hormone-treated rats. 2. In kidney cortex of
      diabetic, cortisone-treated and growth hormone-treated rats the activities of
      glucose 6-phosphatase (EC 3.1.3.9), fructose 1,6-diphosphatase (EC 3.1.3.11) and
      phosphopyruvate carboxylase (EC 4.1.1.32) were increased. 3. The activities of
      glutamate dehydrogenase (EC 1.4.1.3), alanine aminotransferase (EC 2.6.1.2),
      aspartate aminotransferase (EC 2.6.1.10) and pyruvate carboxylase (EC 6.4.1.1)
      were increased in diabetic and cortisone-treated rats. In growth hormone-treated
      rats the activity of aspartate aminotransferase was depressed but those of the
      other three enzymes were unchanged. 4. The activity of hexokinase (EC 2.7.1.1)
      was not altered in any of these conditions. Phosphofructokinase (EC 2.7.1.11)
      activity was depressed only in growth hormone-treated rats. Pyruvate kinase (EC
      2.7.1.40) activity was depressed in cortisone-treated and growth hormone-treated
      rats but unchanged in diabetic rats. 5. Amino acids, acetyl-CoA and glucose 6
      phosphate contents were increased in rat kidneys in all these three conditions.
      Ammonia content was increased in diabetic and cortisone-treated rats but was
      markedly diminished in growth hormone-treated rats. 6. The [lactate]/[pyruvate]
      ratio was elevated in diabetic and cortisone-treated rats but unchanged in growth
      hormone-treated rats. Citrate content was increased in the kidney cortex of
      diabetic and growth hormone-treated rats but was unchanged in cortisone-treated
      rats. The activity of ATP citrate lyase (EC 4.1.3.8) was depressed in diabetic
      and growth hormone-treated rats but was increased in cortisone-treated rats. 7.
      Glycogen content was moderately elevated in growth hormone-treated rats and
      markedly elevated in diabetic rats, whereas no change in glycogen content was
      observed in cortisone-treated rats. Glycogen synthetase (EC 2.4.1.11) activity
      was unchanged in all these three conditions. Phosphorylase (EC 2.4.1.1) activity
      was not affected in cortisone-treated rats but was depressed in diabetic and
      growth hormone-treated rats.

PMID- 4345357
TI  - Effects of starvation on intermediary metabolism in the lactating cow. A
      comparison with metabolic changes occurring during bovine ketosis.
AB  - 1. The purpose of this study was to determine the nature of the metabolic changes
      associated with carbohydrate and fat metabolism that occurred in the blood and
      liver of lactating dairy cows during starvation for 6 days. 2. During starvation,
      the blood concentrations of the free fatty acids and ketone bodies increased,
      whereas that of citrate decreased. After an initial increase, the blood
      concentration of glucose subsequently declined as starvation progressed.
      Starvation caused a significant decrease in the plasma concentration of serine
      and a significant increase in that of leucine. 3. After 6 days of starvation the
      hepatic concentrations of oxaloacetate, citrate, phosphoenolpyruvate, 2
      phosphoglycerate, 3-phosphoglycerate, glucose, glycogen, ATP and NAD(+) had all
      decreased, as had the hepatic activities of phosphopyruvate carboxylase (EC
      4.1.1.32) and pyruvate kinase (EC 2.7.1.40). 4. The above metabolic changes are
      similar to those previously found to occur in cows suffering from spontaneous
      ketosis (Baird et al., 1968; Baird & Heitzman, 1971). 5. Milk yield decreased
      progressively during starvation. 6. There were marked differences in the ability
      of individual animals to resist the onset of severe starvation ketosis.

PMID- 4345359
TI  - [EPR of tyrosine hydrochloride single crystals gamma-irradiated at 290 degrees
      K].

PMID- 4345358
TI  - Inducible phosphoenolpyruvate-dependent hexose phosphotransferase activities in
      Escherichia coli.
AB  - 1. A method is described for measuring the rate of phosphoenolpyruvate-dependent
      phosphotransferase activity for a variety of hexoses in toluene-treated
      suspensions of Escherichia coli. 2. The specific activities of the
      phosphotransferases that catalyse the phosphorylation of hexoses are greatly
      affected by the carbon source for growth. 3. In all strains of E. coli tested,
      fructose phosphotransferase activity is induced by growth on fructose. 4. Strains
      of E. coli differ greatly in the rate at which they phosphorylate glucose, but
      all strains possess at least a low glucose phosphotransferase activity under any
      tested condition of growth. Glucose phosphotransferase activity is further
      induced by growth on glucose; this does not occur in a mutant that lacks the
      ability to take up methyl alpha-d-[(14)C]glucopyranoside and hence grows poorly
      on glucose. 5. When growing on fructose, two strains of E. coli synthesize the
      inducible glucose phosphotransferase system gratuitously, and to specific
      activities higher than observed during growth on glucose. A phosphotransferase
      catalysing the phosphorylation of mannose is similarly induced.

PMID- 4345360
TI  - [Modelling changes in cell adhesion permeability on bimolecular phospholipid
      membranes].

PMID- 4345361
TI  - [Problems of modern biophysics in the light of heat measurements].

PMID- 4345362
TI  - [Detection of copper in cells and tissues by the EPR method].

PMID- 4345363
TI  - [Biophysics and bases of radiation effects].

PMID- 4345364
TI  - [Electron paramagnetic resonance spectra of ribonuclease, photosensitized with
      proflavine].

PMID- 4345365
TI  - [Inactivation of glyceraldehyde-3-phosphate dehydrogenase from rabbit heart by
      free fatty acids].

PMID- 4345366
TI  - [Highly purified cytochrome c-553 from Kirchneriella obesa green algae].

PMID- 4345367
TI  - [Mechanism of inactivation of the respiratory chain by cobra venom
      phospholipase].

PMID- 4345368
TI  - [Delta-aminolevulinic acid synthetase in the gray matter of brain hemispheres].

PMID- 4345369
TI  - [Enzymatic degradation of N-modified analogs of angiotensin II by human blood
      plasma].

PMID- 4345370
TI  - [Physicochemical and functional characteristics of polyribosomes of normal and
      malignant rat cells].

PMID- 4345371
TI  - The value of hydroxyurea in assessing repair synthesis of DNA in HeLa cells.

PMID- 4345372
TI  - [2 cases of severe ethambutol neuropathy].

PMID- 4345373
TI  - [Polyneuropathy due to glue-sniffing--2 cases involving identical twins].

PMID- 4345374
TI  - [Feedback between primary and secondary structures of globular proteins].

PMID- 4345375
TI  - [Effect of acetic anhydride in the presence of perchloric acid on the ethyl ester
      of 2-cyclopentanoneglyoxylic acid].

PMID- 4345376
TI  - Osteopathic manipulation for syndromes of the brachial plexus.

PMID- 4345377
TI  - Alterations of blood sugar and plasma insulin after cryosurgery of functioning
      islet-cell tumor.

PMID- 4345379
TI  - [Brain neoplasms and radiotherapy. 2].

PMID- 4345378
TI  - [Effect of sulpyrin on uric acid analysis].

PMID- 4345380
TI  - Isolation and characterization of temperature-sensitive mutants in a Chinese
      hamster cell line.

PMID- 4345381
TI  - [The Bragg Peak proton beam in stereotaxic neurosurgery].

PMID- 4345382
TI  - Clinical and cytologic responses of postmenopausal women to estrogen.

PMID- 4345383
TI  - Long-distance, "sensory-bombardment" ESP in dreams: a failure to replicate.

PMID- 4345384
TI  - Central cholinergic mechanisms in the thermoregulation of the rat.

PMID- 4345385
TI  - Paradoxic temperature sensations and the problem of modality-specificity of nerve
      fibres in the anterolateral tract of the spinal cord.

PMID- 4345386
TI  - [Lipoprotein metabolism in pyridoxine deficiency].

PMID- 4345387
TI  - Pulmonary contribution to angiotensin I conversion in children.

PMID- 4345388
TI  - Some ideas of a neurosurgeon about the necessity of organising the rehabilitation
      work.

PMID- 4345389
TI  - A new method for quantitative evaluation of bladder sensibility.

PMID- 4345390
TI  - Review of the present state of assessment and treatment of reno-vascular
      hypertension.

PMID- 4345391
TI  - Are some of the connective tissue diseases due to infectious agents?

PMID- 4345392
TI  - The management of abdominal malignancy in children.

PMID- 4345393
TI  - [Control of free fatty acids in skin and adnexa by using imidazole. Application
      in the therapy of acne vulgaris].

PMID- 4345394
TI  - [Anti-herpetic vaccination by nasal route in rabbits].

PMID- 4345395
TI  - A micrometabolic inhibition test for the estimation of poliovirus neutralizing
      antibodies.
AB  - A modified micrometabolic inhibition test for the titration of poliovirus
      neutralizing antibodies is described. The effects of varying both the duration
      and the temperature of incubation of the serum-virus mixtures were examined.
      Overnight incubation resulted in a 2-3-fold increase in the titre of the
      hyperimmune sera tested. The method is simple and economical and appears to be
      suitable for antibody surveys.

PMID- 4345396
TI  - [Interaction of estradiol, estrone and estriol with cytosoluble and nuclear
      receptors of the uterus of immature rats].

PMID- 4345397
TI  - [Estradiol and in vitro RNA biosynthesis in isolated nuclei of healthy and
      tumoral epithelial cells from the uterine cervix].

PMID- 4345398
TI  - [A new virus of the turnip yellow mosaic group: the gombo mosaic virus (Hibiscus
      esculentus L. Malvaceae)].

PMID- 4345399
TI  - Cyclic 3',5'-nucleotide monophosphate phosphodiesterase activity in hepatomas of
      different growth rates.

PMID- 4345400
TI  - Quantitative aspects of transplacental tumor induction with ethylnitrosourea in
      rats.

PMID- 4345401
TI  - Ultramorphological and ultracytochemical studies on tubuloreticular structures in
      lymphoid cells.

PMID- 4345402
TI  - Electrophoretic analysis of microsomal smooth membrane proteins in rat liver and
      in Morris hepatoma 5123C.

PMID- 4345403
TI  - Ultrastructural study of liver invasion by Novikoff hepatoma.

PMID- 4345404
TI  - Urethan and x-ray effects on mice of a tumor-resistant strain, X-Gf.

PMID- 4345405
TI  - Electron microscopic study of neoplasms induced by urethan and x-rays in X-Gf
      mice.

PMID- 4345406
TI  - Regulation of the Embden-Meyerhof pathway in a transplantable rat thyroid tumor.

PMID- 4345407
TI  - Ultrastructural characterization of hamster cells transformed following exposure
      to ultraviolet-irradiated herpes simplex virus type 2.

PMID- 4345408
TI  - Morphological studies of angiosarcomas induced by 1,2-dimethylhydrazine
      dihydrochloride in Syrian golden hamsters.

PMID- 4345409
TI  - Elevation of peptidylproline hydroxylase activity and collagen synthesis in
      spontaneous primary mammary cancers of inbred mice.

PMID- 4345410
TI  - Workshop in human tumor immunology.

PMID- 4345411
TI  - Intestinal alkaline phoshatase and phytase of chicks: separation of isoenzymes,
      zinc contents and in vitro effects of zinc.

PMID- 4345412
TI  - Subcellular localization of thyroglobulin taken up by pig thyroid slices.

PMID- 4345413
TI  - A 6-hour bioassay for pituitary gonadotrophins based on radioactive phosphorus
      uptake by chick testes.

PMID- 4345414
TI  - Hormonal regulation of uridine diphosphatase during spermatogenesis in the rat.

PMID- 4345416
TI  - Phosphatidic acid as a precursor of phosphoinositide in the thyroid.

PMID- 4345415
TI  - Alterations in lipolysis, adenylate cyclase and adenosine 3', 5'-monophosphate
      levels in isolated fat cells following adrenalectomy.

PMID- 4345417
TI  - In vivo effect of GH, ACTH, TSH on thymic anaerobic glycolysis.

PMID- 4345418
TI  - Changing patterns of circulating corticosteroids in rabbits following prolonged
      treatment with ACTH.

PMID- 4345419
TI  - Role of bristle-coated membrane in the uptake of ferritin by rat macrophages.

PMID- 4345420
TI  - Bovine luteal cells in tissue culture.

PMID- 4345421
TI  - Modified distribution of some cyclic AMP phosphodiesterase activities following
      growth of L cell fibroblasts in presence of prostaglandin E 1 .

PMID- 4345422
TI  - Alterations of mouse embryo cells during in vitro aging.

PMID- 4345423
TI  - Effect of chloramphenicol on mitochondrial and extramitochondrial systems in the
      isolated perfused rat heart.

PMID- 4345424
TI  - Nucleo-cytoplasmic protein migration during the activation of chick erythrocyte
      nuclei in heterokaryons.

PMID- 4345425
TI  - The influence of cell hybridization between B77 virus producing RBI rat cells and
      L cells on B77 virus and avian Gs antigen production.

PMID- 4345426
TI  - Tumour cell surface specialization in the uptake of nutrients evidenced by
      cinemicrography as a phenotypic condition for density independent growth.

PMID- 4345427
TI  - Thymus and other lymphoid structures in chickens with Rous sarcoma.

PMID- 4345428
TI  - AMP nucleosidase from Azotobacter vinelandii. 3. Kinetics of allosteric
      interactions.

PMID- 4345429
TI  - The redox reactions in propionic acid fermentation. II. Purification of NAD
      independent glycerolphosphate dehydrogenase bound to minute particles from
      supernatant fraction of Propionibacterium arabinosumm.

PMID- 4345430
TI  - Guanosine triphosphate-dependent enzymatic binding of amino-acyl-transfer
      ribonucleic acid to silk gland ribosomes.

PMID- 4345431
TI  - Studies on a nuclear petite.

PMID- 4345432
TI  - An NAD-linked  -glycerophosphate dehydrogenase in rat liver mitochondria and its
      response to thyroid hormone.

PMID- 4345433
TI  - Isolation and analysis of glycopeptides from microsomes of an ascites hepatoma,
      AH 66.

PMID- 4345434
TI  - Multimolecular forms of pyruvate kinase. II. Purification of M 2 -type pyruvate
      kinase from Yoshida ascites hepatoma 130 cells and comparative studies on the
      enzymological and immunological properties of the three types of pyruvate
      kinases, L, M 1 , and M 2 .

PMID- 4345435
TI  - Ligand size-dependent conformational difference in spin-labeled hemoglobin
      nitrosobenzene derivatives.

PMID- 4345436
TI  - Studies on polypeptide elongation factor from E. coli. I. Crystalline factor G.

PMID- 4345437
TI  - Interactions between NADH-cytochrome b5 reductase and cytochrome b5 preparations
      purified from liver microsomes.

PMID- 4345438
TI  - Mode of operation of ampullae of Lorenzini of the skate, Raja.
AB  - Ampullae of Lorenzini are sensitive electroreceptors. Applied potentials affect
      receptor cells which transmit synaptically to afferent fibers. Cathodal stimuli
      in the ampullary lumen sometimes evoke all-or-none "receptor spikes," which are
      negative-going recorded in the lumen, but more frequently they evoke graded
      damped oscillations. Cathodal stimuli evoke nerve discharge, usually at stimulus
      strengths subthreshold for obvious receptor oscillations or spikes. Anodal
      stimuli decrease any ongoing spontaneous nerve activity. Cathodal stimuli evoke
      long-lasting depolarizations (generator or postsynaptic potentials) in afferent
      fibers. Superimposed antidromic spikes are reduced in amplitude, suggesting that
      the postsynaptic potentials are generated similarly to other excitatory
      postsynaptic potentials. Anodal stimuli evoke hyperpolarizations of nerves in
      preparations with tonic activity and in occasional silent preparations;
      presumably tonic release of excitatory transmitter is decreased. These data are
      explicable as follows: lumenal faces of receptor cells are tonically (but
      asynchronously) active generating depolarizing responses. Cathodal stimuli
      increase this activity, thereby leading to increased depolarization of and
      increased release of transmitter from serosal faces, which are inexcitable.
      Anodal stimuli act oppositely. Receptor spikes result from synchronized receptor
      cell activity. Since cathodal stimuli act directly to hyperpolarize serosal
      faces, strong cathodal stimuli overcome depolarizing effects of lumenal face
      activity and are inhibitory. Conversely, strong anodal stimuli depolarize serosal
      faces, thereby causing release of transmitter, and are excitatory. These
      properties explain several anomalous features of responses of ampullae of
      Lorenzini.

PMID- 4345439
TI  - Cyclic adenosine monophosphate in the nervous system of Aplysia californica. I.
      Increased synthesis in response to synaptic stimulation.
AB  - In the isolated abdominal ganglion of Aplysia, previously incubated in adenine
      (3)H, the amount of (3)H-labeled adenosine-3',5' monophosphate (cAMP) doubled
      after electrical stimulation of nerves at a physiological rate (1/sec). No change
      was detected after 4 min of stimulation. An increase in cAMP was first seen after
      15 min; lengthening the period of stimulation to 1 hr did not increase the extent
      of the effect. ATP contained 50% of the total radioactivity taken up from adenine
      (3)H, cAMP about 0.1%. During stimulation both the total amount and the specific
      radioactivity of adenosine triphosphate (ATP) did not change. Thus, the increased
      amount of radioactivity found in cAMP after stimulation represented an increase
      in its rate of synthesis. During stimulation formation of cAMP-(3)H was not
      altered in nerves or in the cell body of an identified neuron (R2). In addition,
      no changes were detected in the total amounts of cAMP in the ganglion and in the
      cell body of R2. It seems likely that the increase was initiated by synaptic
      activity rather than by action potentials. It was blocked by elevating the
      concentration of Mg, which also blocks synaptic activity without impairing
      conduction of impulses. Moreover, impulse activity induced by ouabain and
      glutamate did not result in increased formation of cAMP.

PMID- 4345441
TI  - Variation of alcohol dehydrogenase levels in Drosophila species hybrids.

PMID- 4345440
TI  - Cyclic adenosine monophosphate in the nervous system of Aplysia californica. II.
      Effect of serotonin and dopamine.
AB  - Serotonin and dopamine, both likely transmitter substances in Aplysia, stimulated
      formation of adenosine-3',5' monophosphate (cAMP) in ganglia, connectives, and
      identified nerve cell bodies. This widespread distribution suggests that
      receptors for the response are localized throughout the nervous system, as is
      adenyl cyclase. Both synthesis of cAMP-(3)H from precursor previously labeled in
      incubations with adenine-(3)H and total content of cAMP were stimulated up to 15
      fold. The acetylcholine analogue carbachol, glutamate, norepinephrine, and
      histamine were inactive. Full stimulation occurred within 2-4 min of applying
      serotonin; the extent of the effect was half maximal at 6micro serotonin. Even in
      the continued presence of serotonin, the increased cAMP diminished with time.
      When serotonin was removed, tissue remained refractory for 15-20 min; sensitivity
      returned after 25 min. Serotonin stimulated cAMP after removal of extracellular
      Na, K, or Cl and in isotonic sucrose, with all extracellular ions removed.
      Elevating Mg, which blocked the stimulation of cAMP caused by synaptic activity,
      did not affect the response to serotonin. Thus the response appeared to be
      independent of transmitter release and of changes in synaptic potentials and
      current flow. The role of cAMP in neuronal functioning remains to be determined.
      Conditions which markedly increased cAMP in neurons, however, did not affect the
      rate of RNA synthesis, nor did they alter the distribution of phosphorylated
      adenine or uridine nucleotides.

PMID- 4345442
TI  - [Water-electrolyte changes during normal and pathological pregnancy].

PMID- 4345443
TI  - On the site of action of reserpine on ACTH secretion.

PMID- 4345444
TI  - [Angiography of hemangiomas of the liver].

PMID- 4345445
TI  - Arthritis in viral hepatitis. Report of two cases and review of the literature.

PMID- 4345446
TI  - [Physiological basis of the functional exploration of the hypothalamo-hypophyeo
      adrenocortical axis].

PMID- 4345447
TI  - Oat-cell carcinoma and severe hypouricemia.

PMID- 4345448
TI  - [Cerebral changes in the course of pancreatic insulinoma].

PMID- 4345449
TI  - Angiotensin I assays.

PMID- 4345450
TI  - Calcium hypochlorite for disinfection of hydrotherapy equipment.

PMID- 4345451
TI  - [Hematologic changes and viral infection. I. Leukopenia and its physiopathology].

PMID- 4345452
TI  - [A method of isolating enteroviruses from meat (I. Preparation of meat samples
      for analysis)].

PMID- 4345453
TI  - Sympathetic ganglia in culture. II. Accessory cells.

PMID- 4345454
TI  - Fibroblasts as a part of the contractile system in duodenal villi of rat.

PMID- 4345455
TI  - [Functional differentiation of the human placental syncytiotrophoblast].

PMID- 4345456
TI  - [Sclerotin precursors in the vitelline cells of Microdalyellia fairchildi
      (Turbellaria)].

PMID- 4345457
TI  - The effect of bronchoscopic anesthesia upon the yield, accuracy, and cell typing
      ability of bronchial washing cytology.

PMID- 4345458
TI  - Studies on biosynthesis of polymyxin E (colistin). I. Isolation and
      characteristics of mucoidless R-mutants of Bacillus polymyxa K-1.

PMID- 4345459
TI  - Analysis of taxonomic characteristics of highly active viomycin-producing mutants
      of Streptomyces griseus var. purpureus.

PMID- 4345460
TI  - The inner ear in experimental diabetes mellitus.

PMID- 4345461
TI  - Electron microscopic study of the Auer body.

PMID- 4345462
TI  - Carcinoid tumors--review of literature with special references to sites of origin
      and humoral substances produced.

PMID- 4345463
TI  - Primary mixed carcinomas of the bronchus.

PMID- 4345464
TI  - Dumping of patients: funding and statistics a problem.

PMID- 4345465
TI  - Amphetamine psychosis: a "model" schizophrenia mediated by catecholamines.

PMID- 4345466
TI  - Cerebrospinal fluid amine metabolites in affective illness: the probenecid
      technique.

PMID- 4345467
TI  - Dorsal column stimulator implant.

PMID- 4345468
TI  - [Results of an investigation on the frequency of contemporary viral infection
      with hyperpyretic convulsions in children].

PMID- 4345469
TI  - [Esophagomanometric findings in man following intravenous administration of a
      spasmolytic agent].

PMID- 4345471
TI  - [Somatosensory evoked potentials in patients with motor disturbances].

PMID- 4345470
TI  - [Experimental brain tumor in SD-JCL rats induced by ethylnitrosourea administered
      through placenta].

PMID- 4345472
TI  - [Role of cyclic AMP in neuromuscular transmission--with special reference to the
      effect of catecholamines, xanthines and calcium on myasthenic syndrome].

PMID- 4345473
TI  - Management of insomnia.

PMID- 4345474
TI  - [Islet cell adenomatosis associated with therapy watery diarrhea and hypokalemia.
      (Verner-Morrison Syndrome)].

PMID- 4345475
TI  - Some recent developments in the physiology of the thyroid gland.

PMID- 4345476
TI  - Progress in neurobiology and its implications for society.

PMID- 4345477
TI  - Modifications of human spermatozoa glycolysis by cyclic adenosine monophosphate
      (cAMP), estrogens, and follicular fluid.

PMID- 4345478
TI  - Tissue distribution of labelled material in vitamin C-deficient guinea pigs after
      intravenous injection of 1- 14 C) ascorbic acid or (1- 14 C) dehydroascorbic
      acid.

PMID- 4345479
TI  - A quantitative follow up-study of nursing student reactions to an interactional
      group experience.

PMID- 4345480
TI  - The forgotten patient.

PMID- 4345481
TI  - Psychiatric aides in transition.

PMID- 4345483
TI  - Drug dependence: some aspects of prevention and control. Report of a WHO European
      Regional Seminar.

PMID- 4345482
TI  - Sensitivity training in psychiatric nursing: evolution and evaluation of a
      student group experience.

PMID- 4345484
TI  - The "Brand Name" game.

PMID- 4345485
TI  - Increase in benefits for the elderly.

PMID- 4345486
TI  - Crisis-intervention concepts: implications for nursing practices.

PMID- 4345487
TI  - Do perceptual changes occur in crisis? A case study.

PMID- 4345488
TI  - Transient inhibition of polyoma virus synthesis by Sendai virus (parainfluenza
      I). I. Demonstration and nature of the inhibition by inactivated virus.
AB  - Superinfection of polyoma virus-infected mouse embryo cells by beta-propiolactone
      inactivated Sendai virus resulted in a 90% inhibition of the synthesis of
      infectious polyoma progeny. The interference is dependent upon the time of
      superinfection and the concentration of the inactivated virus. The inhibition of
      polyoma virus synthesis is transient in nature since normal synthesis of polyoma
      progeny virus is seen upon prolonged incubation. Interferon does not appear to be
      implicated in the interference. Various aspects of the biological and synthetic
      capabilities of beta-propiolactone-inactivated Sendai virus are also described.

PMID- 4345489
TI  - Transient inhibition of polyoma virus synthesis by sendai virus (parainfluenza
      I). II. Mechanism of the interference by inactivated virus.
AB  - The mechanism of the transient inhibition of polyoma virus synthesis by
      betapropiolactone-inactivated Sendai virus was studied. Polyoma virus early
      functions did not appear to be affected, although deoxyribonucleic acid (DNA) and
      structural protein synthesis were inhibited 60 and 35% respectively. The
      inhibition of macromolecular synthesis was not sufficient to account for the 90%
      inhibition of infectious progeny formation. Encapsidation of polyoma DNA into
      mature virions appears to be completely inhibited after superinfection by beta
      propiolactone-inactivated Sendai virus. Ultraviolet irradiation of live or beta
      propiolactone-inactivated Sendai virus preparations abolishes the interfering
      capacity, indicating that a functional Sendai virus ribonucleic acid molecule is
      the interfering component.

PMID- 4345491
TI  - Adenovirus-associated virus multiplication. IX. Extent of transcription of the
      viral genome in vivo.
AB  - Nucleic acid hybridization procedures were used to measure the extent of
      transcription of adenovirus-associated virus (AAV) deoxyribonucleic acid (DNA) in
      KB cells in the presence of either adenovirus or herpes simplex virus as the
      helper. Annealing of AAV ribonucleic acid to AAV DNA was monitored by a
      hybridization inhibition assay on nitrocellulose filters or by hydroxyapatite
      chromatography. These experiments confirmed the previous observation that, in the
      presence of either type of helper virus, only one strand of AAV DNA (the
      thymidine-rich or "minus" strand) is transcribed in vivo. However, it was found
      that only 70 to 80% of this strand appears to be transcribed in vivo.
      Furthermore, studies with minus strands employing hydroxyapatite chromatography
      and nuclease S(1), which specifically degrades single-stranded DNA, indicated
      that up to 20% of the minus strand is self-complementary. It seems likely that
      these self-complementary sequences account for the bulk of that portion of the
      minus strand (20 to 30%) which is not transcribed in vivo.

PMID- 4345490
TI  - Transcription and transport of virus-specific ribonucleic acids in African green
      monkey kidney cells abortively infected with type 2 adenovirus.
AB  - The techniques of deoxyribonucleic acid-ribonucleic acid (DNA-RNA) hybridization
      and immunological precipitation were used to compare the synthesis of adenovirus
      specific macromolecules in African green monkey kidney (AGMK) cells infected with
      adenovirus, an abortive infection, and coinfected with both adenovirus and simian
      virus 40 (SV40), which renders the cells permissive for adenovirus replication.
      When viral protein synthesis was proceeding at its maximum rate, the
      incorporation of (14)C-amino acids into adenovirus structural proteins was about
      90 times greater in the doubly infected cells than in cells infected only with
      adenovirus. However, the rates of synthesis of virus-specific ribonucleic acid
      appeared to be comparable in the two infections at all times measured. A time
      dependent increase in the rate of RNA synthesis observed late in the abortive
      infection was dependent upon the prior replication of viral DNA. Moreover, all
      virus-specific RNA species that are normally made late in a productive adenovirus
      infection (i.e., the true late and class II early RNA species) were also detected
      in the abortive infection. Adenovirus-specific RNA was detected by molecular
      hybridization in both the cytoplasm and nuclei of abortively infected cells.
      Comparable amounts of viral RNA were found in the cytoplasmic fractions of AGMK
      cells infected either with adenovirus or with both adenovirus and SV40. The
      results of hybridization-inhibition experiments clearly showed that there was a
      class of virus-specific RNA molecules, representing about 30% of the total, in
      the nucleus that was not transported to the cytoplasm. This class of RNA was also
      identified in similar amounts in productively infected human KB cells. The
      difference in the abilities of cytoplasmic and nuclear RNA to inhibit the
      hybridization of virus-specific RNA from whole cells was shown not to be due to a
      difference in the molecular size of the RNA species from the two cell fractions
      or to the specific loss of a cytoplasmic species during RNA extraction
      procedures.

PMID- 4345492
TI  - Temperature-sensitive mutants of vesicular stomatitis virus: in vitro studies of
      virion-associated polymerase.
AB  - The temperature dependence of the virion-associated polymerase activity of six
      temperature-sensitive (ts) mutants of vesicular stomatitis virus (tsW10, 11, 14,
      16B, 28, and 29) has been examined in vitro and compared to the heat-resistant
      parent (HR). The polymerase of five of the mutants (tsW10, 11, 14, 16B, and 28)
      appears to be significantly more ts than that of HR. Because certain pairs of
      these five mutants can complement each other's in vitro polymerase activity, it
      appears that in vitro some components involved in the polymerase of one virion
      can be utilized by another virion. Examination of 19 revertants of tsW11 and
      tsW16B which had regained their ability to replicate at 38 C showed that their in
      vitro polymerase activity had also become less ts. Furthermore, it was found that
      the pairs of mutants which showed in vitro complementation of polymerase activity
      at 38 C were those which had shown complementation in yielding infectious progeny
      in mixedly infected cells. These two observations suggest that the ts behavior of
      the in vitro polymerase activity of the five mutants is related to their
      inability to replicate at the nonpermissive temperature.

PMID- 4345493
TI  - Thermosensitive block of the Sabin strain of poliovirus type I.
AB  - The thermosensitive defect of the Sabin LSc2ab strain of poliovirus type I was
      studied. Transfer of infected KB cells from 36 to 38.5 C resulted in 30%
      inhibition of viral RNA replication but in 90% inhibition of formation of
      virions. Neither 74S procapsids nor 14S particles were detected in the cells
      transferred to the non-permissive temperature. However, procapsids, once
      accumulated at 36 C, were normally stable at 38.5 C and could transform into
      virions at that temperature. Viral proteins synthesized at the nonpermissive
      temperature were not different from those synthesized at permissive temperature,
      as judged from their pattern in polyacrylamide gel electrophoresis and from the
      fact that they normally matured into virions when the infected cells were brought
      back to permissive temperature, even under conditions of inhibition of protein
      synthesis. This leads to the conclusion that the defect in the Sabin strain
      studied lies in the assembly of its viral capsid proteins into capsomeres.

PMID- 4345494
TI  - Mechanism of interferon action: inhibition of viral messenger ribonucleic acid
      translation in L-cell extracts.
AB  - Encephalomyocarditis (EMC) virus ribonucleic acid (RNA) stimulated the
      incorporation of (14)C-amino acids into polypeptides in cell-free systems using
      preincubated S10 extracts from L cells. Incorporation was linear for over 2 hr.
      Analysis of the tryptic peptides derived from the polypeptide products formed in
      response to EMC RNA showed them to be virus specific. The major product, a
      polypeptide of 140,000 in molecular weight, migrated on sodium dodecyl sulfate
      polyacrylamide gels with one of the virus-specific polypeptides present in EMC
      infected cells. A minor component of molecular weight about 230,000 may
      correspond to the product of complete translation of the EMC virus genome. Little
      or no effect of interferon or vaccinia virus infection was observed in the
      preincubated, cell-free system. The EMC RNA-stimulated incorporation of (14)C
      amino acids into polypeptides was not inhibited in extracts derived from L cells
      early in virus infection, from interferon-treated cells, or from cells subjected
      to both treatments. Interferon treatment did appear to have a slight inhibitory
      effect on chain elongation in this system. However, treatment of cells with
      highly purified interferon before virus infection caused a decrease of about 80%
      in the capacity of non-preincubated cell extracts to translate added EMC RNA.
      This effect did not extend to the translation of polyuridylic acid and could be
      reversed by preincubation of the extracts at 37 C for 20 min. The inhibition of
      translation was manifest at interferon concentrations as low as 5IU/ml, and in
      this respect closely paralleled the inhibition of virus growth. Inactivation of
      the antiviral activity of the interferon by heating or digestion with trypsin
      also abolished the effect on cell-free protein synthesis. The EMC-specific
      polypeptides formed in reduced amounts in extracts of interferon-treated vaccinia
      infected cells were smaller than those formed in extracts of untreated, vaccinia
      infected cells. Thus, inhibition of initiation or elongation of polypeptides, or
      both, can be demonstrated in cell-free systems employing non-preincubated
      extracts from interferon-treated, virus-infected cells. These results indicate
      that antiviral activity of interferon is directed against the translation of
      viral messenger RNA.

PMID- 4345495
TI  - Classification of rhabdovirus proteins: a proposal.
AB  - A simple alphabetical classification is offered as a means to codify the proteins
      of rhabdoviruses, using vesicular stomatitis virus as the prototype.

PMID- 4345496
TI  - Density heterogeneity of simian virus 40 ribonucleic acid late after infection of
      permissive cells.
AB  - Ribonucleic acid (RNA) was isolated from CV-1 cells 44 hr after simian virus 40
      (SV40) infection. The molecules containing SV40 base sequences were characterized
      with respect to their buoyant density distribution. The density of these
      molecules was compared to that of single- and double-stranded RNA synthesized by
      using SV40 DNA and Escherichia coli RNA polymerase. The results suggest that
      about 20% of the SV40 RNA in the infected cells consisted of partially double
      stranded molecules.

PMID- 4345497
TI  - Genetic studies on inbreeding in some Japanese populations. VII. The effects of
      parental consanguinity on skeletal age in Shizuoka children.

PMID- 4345498
TI  - The role of alpha-toxin of Clostridium perfringens in experimental gas gangrene
      in guinea pigs.

PMID- 4345500
TI  - Organization man: a study in rigor mortis.

PMID- 4345499
TI  - Where we are and where are we going?

PMID- 4345501
TI  - Possibility that angiotensin resulting from unilateral kidney disease affects
      contralateral renal function.

PMID- 4345502
TI  - Control of the synthesis of fatty-acid synthetase in rat liver by insulin,
      glucagon, and adenosine 3':5' cyclic monophosphate.
AB  - The usual increase in the activity of liver fatty-acid synthetase that occurs on
      refeeding of a fat-free diet to previously fasted rats is abolished in diabetic
      animals. Insulin specifically restores this increase by enhancement of the rate
      of synthesis of fatty-acid synthetase. However, glucagon and cyclic AMP inhibit
      the increase in the activity of fatty-acid synthetase. Therefore, the
      concentration of fatty-acid synthetase in rat liver is under the control of the
      relative concentrations of insulin and glucagon.

PMID- 4345503
TI  - Luteinizing hormone receptors: specific binding of human luteinizing hormone to
      homogenates of luteinized rat ovaries.
AB  - Binding of human [(125)I]luteinizing hormone to homogenates of luteinized rat
      ovaries is dependent upon time, temperature, and pH and is saturable. Injection
      of human chorionic gonadotropin in vivo or addition of unlabeled human chorionic
      gonadotropin or human or ovine luteinizing hormone in vitro inhibits binding,
      whereas follicle stimulating hormone or prolactin is without effect. The
      dissociation constant for binding of luteinizing hormone receptor is 0.79 nM. The
      number of binding sites is 94 femtomol/mg of wet weight. NaCl, KCl, MgSO(4), and
      CaCl(2) at concentrations below 10 mM have no effect on binding, while all salts
      significantly inhibit binding at 150 mM. Binding of [(125)I]luteinizing hormone
      to its receptors is destroyed by proteolytic enzymes and by phospholipase C and
      D. The total binding activity is quantitatively recovered in the 2000 x g pellet
      of the homogenate.

PMID- 4345504
TI  - Alteration of nucleoside transport of Chinese hamster cells by dibutyryl
      adenosine 3':5'-cyclic monophosphate.
AB  - Cultured Chinese hamster ovary cells showed no significant change in generation
      time or fraction in the S-phase in the presence of 1 mM N(6),O(2')-dibutyryl
      adenosine 3':5'-cyclic monophosphate. Growth continued for at least two
      generations after expression of the morphological transformation induced by this
      cyclic AMP analog. Despite identical growth rates, apparent rates of DNA and RNA
      synthesis (incorporation of [(3)H]-thymidine or [(3)H]uridine) were reduced up to
      15-fold in log phase by 1 mM cyclic nucleotide. [(3)H]Deoxycytidine incorporation
      was much less sensitive to dibutyryl cyclic AMP. Uptake studies with
      [(3)H]thymidine demonstrated an inhibition of transport rate dependent on the
      concentration of dibutyryl cyclic AMP in the growth medium. The rate of thymidine
      uptake at 1 degrees was decreased 21-fold by 1 mM cyclic nucleotide; half-maximal
      inhibition occurred at 6 muM. At 37 degrees , the pool size of acid-soluble
      thymidylate was strongly reduced by 1 mM cyclic nucleotide, and synergistic
      reduction of the pool size was found with 0.5 mM aminophylline. Phosphorylation
      of the acid-soluble intracellular label was unaffected by dibutyryl cyclic AMP.
      Inhibition of thymidine uptake is attributed to an observed decrease in thymidine
      kinase activity caused by growth in 1 mM dibutyryl cyclic AMP, and possibly to a
      simultaneous alteration in membrane permeability. Kinase-facilitated uptake of
      other metabolites may be regulated in a similar fashion by cyclic AMP.

PMID- 4345505
TI  - Initiation of picornavirus protein synthesis in ascites cell extracts.
AB  - The current model of picornavirus protein formation implies that initiation of
      protein synthesis occurs at a single site on the viral RNA, and that the large
      polypeptide formed is later cleaved. A direct test of this model was made in
      vitro by studying the incorporation of [(35)S]methionine from rabbit liver Met
      tRNA(M) (Met) and fMet-tRNA(F) (Met) into encephalomyocarditis virus RNA-coded
      proteins in extracts of Ehrlich ascites cells. The incorporation of N
      formylmethionine was complete within 5 min, while utilization of Met-tRNA(M)
      (Met) continued for 20 min. Tryptic digests of [(35)S]methionine-labeled products
      from Met-tRNA(M) (Met) analyzed by anion-exchange chromatography yielded more
      than 30 peptides, as compared to about 15 [(35)S]methionine-labeled peptides from
      purified encephalomyocarditis virus. In contrast, products labeled with fMet
      tRNA(F) (Met) yielded one major (26)S-labeled tryptic peptide. The N-terminal
      location of methionine in this peptide was verified by Edman degradation. One
      predominant N-terminal tryptic peptide was also obtained with fMet-tRNA(F) (Met)
      when mouse Elberfeld and mengo-virus RNAs were used as messengers. On the basis
      of N-terminal compared with internal labeling of the products, no evidence for in
      vitro post-translational cleavage was found. The results are consistent with a
      single initiation site for synthesis of picornavirus proteins.

PMID- 4345506
TI  - Translation of encephalomyocarditis viral RNA in oocytes of Xenopus laevis.
AB  - RNA from encephalomyocarditis virus was injected into oocytes of Xenopus laevis.
      After incubation of the oocytes in [(35)S]methionine, polyacrylamide gel
      electrophoresis showed that a new series of polypeptides had been synthesized.
      They were identical in size to the polypeptides that appeared in ascites cells
      after infection with this virus. Electrophoretic and chromatographic analysis of
      the methionine-containing tryptic peptides from three of the induced polypeptides
      confirmed that they were virus-specific. All of the bands that appeared in
      ascites cells after infection also appeared in oocytes after injection of RNA
      from the virus. We conclude that Xenopus oocytes translate a mammalian viral mRNA
      faithfully and extensively, and perform normal post-translational modifications.

PMID- 4345507
TI  - Hormonal interactions in the uterus: inhibition of isoproterenol-induced
      accumulation of adenosine 3':5'-cyclic monophosphate by oxytocin and
      prostaglandins.
AB  - Interactions of hormones stimulating and inhibiting uterine contraction were
      studied in vitro in uteri from oophorectomized rats. The beta-adrenergic
      effector, isoproterenol, a potent inhibitor of contraction, produced a dose
      related increase of adenylate cyclase and accumulation of adenosine 3':5'-cyclic
      monophosphate (cAMP) that was inhibitable by propranolol. Oxytocin, which
      stimulates contraction, effectively inhibited accumulation of uterine cAMP
      induced by isoproterenol in the presence or absence of theophylline.
      Prostaglandins E(2) and F(2alpha), each at a maximum effective concentration of
      0.5 muM, also inhibited accumulation of cAMP induced by isoproterenol, consistent
      with their effect in stimulation of uterine contraction. Prostaglandin E(2), but
      not prostaglandin F(2alpha), stimulated cAMP accumulation in a dose-related
      manner at concentrations in excess of 0.5 muM. Neither propranolol nor oxytocin
      inhibited that response. Bovine endometrial adenylate cyclase failed to respond
      to isoproterenol but was stimulated by prostaglandins E(1) and E(2). When
      myometrial preparations were studied, isoproterenol stimulation and prostaglandin
      effects were observed as for whole castrate uterus. The competitive physiological
      actions of beta-adrenergic effectors on the one hand, and oxytocin and
      prostaglandins on the other hand, are based on their influences on a myometrial
      adenylate cyclase. Stimulation of uterine cAMP accumulation by prostaglandin E(2)
      is due to action at a different and unrelated site.

PMID- 4345508
TI  - A DNA fragment of Herpes simplex 2 and its transcription in human cervical cancer
      tissue.
AB  - A human cervical tumor, free of detectable infectious herpes simplex 2 virus,
      contained a fragment comprising 39% of herpes viral DNA. Renaturation kinetics
      indicate that an average of 1 to 3.5 DNA fragments of herpes simplex virus are
      present per cell, depending on the ploidy of the cells in this particular tumor.
      Virus-specific sequences were found linked to highly repetitive sequences of host
      DNA, which reassociated under conditions designed to preclude reassociation of
      viral sequences. The tumor also contained RNA transcripts complementary to 5% of
      the viral DNA. The fraction of viral DNA template transcribed in the cervical
      tumor is considerably less than that transcribed in productively infected cells
      (50%).

PMID- 4345509
TI  - Isolation and subunit structure of polycytidylate-dependent RNA polymerase of
      encephalomyocarditis virus.
AB  - A polycytidylate-dependent RNA polymerase of encephalomyocarditis virus was
      isolated from infected BHK 21 cells. The enzyme was associated with a smooth
      membrane fraction, from which it was extracted by a mixture of sodium dodecyl
      sulfate, Triton X-100, and dithiothreitol, and further purified by chromatography
      on a Dowex-1 column and by glycerol gradient sedimentation. Analysis of a 6S
      glycerol gradient peak of RNA polymerase activity by sodium dodecyl sulfate
      polyacrylamide gel electrophoresis revealed the presence of five polypeptides, of
      molecular weights 72,000, 65,000, 57,000, 45,000, and 35,000. The molecular
      weights of four of the polypeptides (72,000, 65,000, 45,000, and 35,000) are
      almost identical to the reported molecular weights of the four subunits of Qbeta
      replicase.

PMID- 4345510
TI  - Selective inhibition of growth of transformed cells by protease inhibitors.
AB  - Five protease inhibitors with different modes of action were found to reduce the
      growth of transformed mouse (Py3T3, SV3T3, and 3T12) and hamster (PyBHK) cells.
      Some of these inhibitors caused the transformed cells to cease growth at
      saturation densities characteristic for nontransformed cells. The protease
      inhibitors were strikingly selective with regard to the transformed cells; they
      had essentially no effect on the growth of the nontransformed cells. From this
      result, it is concluded that the inhibitors block a protease-like activity that
      is required for the unrestrained growth of transformed cells. The inhibitors
      exerted their effect directly on the cells; they did not affect growth by
      interacting with serum components of the medium.

PMID- 4345511
TI  - Pararticular soft tissue changes in systemic diseases.

PMID- 4345513
TI  - [Electrophysiology of the neuron].

PMID- 4345512
TI  - Tumors of the soft tissues of the extremities.

PMID- 4345514
TI  - Effects of adrenal cortical hormones on carbohydrate, protein, and fat
      metabolism.

PMID- 4345515
TI  - Phosphoenolpyruvate carboxykinase. II. Hormonal controls.

PMID- 4345516
TI  - Evaluation of optic neuropathy with B-scan ultrasonography.

PMID- 4345517
TI  - A follow-up study of narcotic addicts in the NARA program.

PMID- 4345518
TI  - Issues raised in a group setting by patients recovering from myocardial
      infarction.

PMID- 4345519
TI  - Multivesicular bodies and related structures of the syncytiotrophoblast of human
      term placenta.

PMID- 4345520
TI  - Uptake of Adenovirus by intestinal absorptive cells of the suckling rat. I. The
      neonatal ileum.

PMID- 4345521
TI  - Uptake of adenovirus by intestinal absorptive cells of the suckling rat. II. The
      neonatal jejunum.

PMID- 4345522
TI  - Trout hepatoma: fibrosis and lymphocytosis as suppressive mechanisms in the
      rainbow trout (Salmo gairdneri).

PMID- 4345523
TI  - Neutrophil proteases in inflammation.

PMID- 4345524
TI  - Abetalipoproteinemia.

PMID- 4345525
TI  - Epstein-Barr virus infection in relation to infectious mononucleosis and
      Burkitt's lymphoma.

PMID- 4345526
TI  - Transsulfuration in fetal and postnatal mammalian liver and brain. Cystathionine
      synthase, its relation to hormonal influences, and cystathionine.

PMID- 4345527
TI  - Structure-melanotropic activity relationship in synthetic polypeptides related to
      ACTH.

PMID- 4345528
TI  - Some aspects of the relationship between N-terminal structure and MSH activity of
      three decapeptides related to ACTH: a comparative study of gly 1 -ACTH(1-10)OH,
      ibu 1 -ACTH(1-10)OH and  -ala 1 -ACTH(1-10)OH.

PMID- 4345529
TI  - Isolation of prolactin granules from rat anterior pituitary glands.

PMID- 4345530
TI  - Thyrotropin and thyroidal peroxidase activity.

PMID- 4345532
TI  - ACTH and MSH production by a single cloned mouse pituitary tumor cell line.

PMID- 4345531
TI  - The initiation of fetal adrenocorticotrophic activity in the rat.

PMID- 4345533
TI  - Biological activity of 1,25-dihydroxyvitamin D3 in the rat.

PMID- 4345534
TI  - A chick bioassay for parathyroid hormone.

PMID- 4345535
TI  - Avian bioassay method for parathyroid hormone.

PMID- 4345536
TI  - Use of a modified radioligand assay to measure the effect of estradiol on uterine
      adenosine 3',5'-cyclic monophosphate.

PMID- 4345537
TI  - Effects of methylxanthines on adenosine 3',5'-monophosphate and corticosterone in
      the rat adrenal.

PMID- 4345538
TI  - Effects of cholera and E. coli enterotoxins on cyclic adenosine 3',5'
      monophosphate levels and intermediary metabolism in the thyroid.

PMID- 4345539
TI  - Adenosine 3',5'-cyclic monophosphate and phosphodiesterase activities in isolated
      fetal and neonatal rat pancreatic islets.

PMID- 4345540
TI  - Effects of subunits of TSH and LH on TSH stimulation of cyclic AMP accumulation
      in dog thyroid slices.

PMID- 4345541
TI  - Stereoisomerism in adrenergic drugs.

PMID- 4345542
TI  - [The importance of the sympatho-adrenal system during periods of rest and during
      adaptation to muscular activity].

PMID- 4345543
TI  - [Correlation of post-synaptic activity and surface potentials in the giant
      pyramidal field of the cat cortex].

PMID- 4345544
TI  - [A method of measuring motor neuron membrane impedance during synaptic activity].

PMID- 4345545
TI  - Islet cell tumour in the newborn.

PMID- 4345546
TI  - Autoimmune hemolytic anemia and cytomegalovirus infection in a six-months-old
      child, treated with azathioprine.

PMID- 4345547
TI  - Studies on invasiveness of polyoma virus transformed BHK cells on chorioallantoic
      membrane of chick.

PMID- 4345548
TI  - The role of viruses in the pathogenesis of ocular tumors.

PMID- 4345549
TI  - Trapping of radicals formed in the photochemical reaction between hydrogen
      peroxide and some pyrimidine bases, nucleosides, nucleotides, and yeast nucleic
      acid.

PMID- 4345550
TI  - Oxidation of heme proteins by alkyl halides.

PMID- 4345551
TI  - Reversible disaggregation of myofilaments in vertebrate smooth muscle.
AB  - Strips of taenia coli from guinea pigs were incubated under isometric conditions
      in Krebs-Ringer bicarbonate saline (MKR) containing various concentrations of
      Ca(+2) and/or Mg(+2). Spontaneous or chemically induced contractile activity was
      abolished within 15 min of exposure to MKR containing Ca(+2) at concentrations
      below 10(-6) M; contractile activity was restored by reincubation in normal MKR
      after 1-2 h. Exposure of taenia coli to MKR containing Ca(+2) at concentrations
      below 10(-6) M for 1 h or more led to loss of thick and thin myofilaments from
      the sarcoplasm as observed with the electron microscope. Except for the loss of
      these two filament types, the cells contained all other structural features
      observed in preparations incubated in MKR containing Ca(+2) at its normal level
      (1.3 x 10(-3) M). The loss of thick and thin myofilaments in strips exposed to a
      Ca(+2) concentration below 10(-6) M was reversed by reincubation for 30 min in
      MKR containing normal Ca(+2) levels. The observed loss of thick and thin
      myofilaments in response to low Ca(+2) is interpreted as resulting from the
      disaggregation of some or all of the molecular components of these two filament
      types.

PMID- 4345552
TI  - Contact-inhibited revertant cell lines isolated from SV 40-transformed cells. IV.
      Microfilament distribution and cell shape in untransformed, transformed, and
      revertant Balb-c 3T3 cells.
AB  - A COMPARISON IS MADE OF THE ULTRASTRUCTURE OF THE CELL PERIPHERY IN THREE CLONED
      CELL LINES: untransformed Balb/c 3T3 cells, SV40-transformed Balb/c 3T3 cells,
      and revertant cells obtained from the transformed cell line by a selection
      technique utilizing concanavalin A. Both thin-section and surface replication
      techniques are used for in situ examination of the cell lines. Microfilaments, 70
      A in diameter (called alpha filaments), are abundant in untransformed and
      revertant cell lines, particularly in the anterior expansions of the cells, which
      tend to have many microvilli and small pseudopodia. Alpha filaments are
      diminished in the anterior expansions of transformed cells, which contain large
      blunt pseudopodia and relatively few microvilli. Surface replicas confirm the
      impression gained from thin sections that transformed cells have a greater
      proportion of their cell surface involved in bulging pseudopodia than either
      untransformed or revertant cells. Since alpha filaments are shown to bind heavy
      meromyosin and are similar to F-actin, these filaments are thought to be
      important in cell motility. These observations suggest that a close relationship
      exists between decreased alpha filaments, bulging pseudopodia, and loss of
      contact inhibition of movement in transformed cells.

PMID- 4345553
TI  - Regulation of microtubules in Tetrahymena. I. Electron microscopy of oral
      replacement.
AB  - The coupled resorption and redifferentiation of oral structures which occurs in
      Tetrahymena pyriformis under conditions of amino acid deprivation has been
      studied by transmission electron microscopy. Two patterns of ciliary resorption
      have been found, (a) in situ, and (b) after withdrawal into the cytoplasm. No
      autophagic vacuoles containing cilia or ciliary axonemes have been seen.
      Stomatogenic field basal bodies arise by a process of rapid sequential
      nucleation, with new ones always appearing next to more mature ones, even though
      the latter may not be fully differentiated. Accessory radial ribbons of
      microtubules develop immediately adjacent to oral field basal bodies as a late
      step in their maturation. It can be seen that the formation of basal bodies and
      their orientation within the oral complex are separate processes. This is true
      for about 130 of the approximately 170 oral basal bodies; the remaining 40 or so
      form within the patterned groups of ciliary units as a later event. Clusters of
      randomly oriented thin-walled microtubules are found surrounding oral basal
      bodies at all times during stomatogenesis. They may either represent stores of
      microtubule subunit protein, or serve as effectors of basal body movement during
      their orientation into pattern.

PMID- 4345554
TI  - Rapid degeneration of ampullary electroreceptor organs after denervation.
AB  - Electroreceptors (ampullary organs) of the transparent catfish (Kryptopterus
      bicirrhus) lie in the epidermis, and contain spherical receptor cells that
      receive purely afferent innervation from the lateral line nerve. Section of this
      nerve causes rapid degenerative changes to occur in the receptors. Fine
      structural alterations occur in the receptor cell synapses and nerve fiber 6-12 h
      postoperatively. Disruption of the receptor cells begins by 18 h and most are
      lost by 48 h. By 72 h supporting cells and secretory cells also show marked
      degeneration, and by 96 h they may be totally lost. The rapid degeneration of the
      electroreceptor organs of Kryptopterus should make them a useful preparation for
      analysis of neurotrophic functions.

PMID- 4345555
TI  - Dibutyryl cyclic adenosine 3'5' monophosphate, sugar transport, and regulatory
      control of cell division in normal and transformed cells.
AB  - Swiss 3T3 cells exhibit contact-regulated cell growth and have a lower ability to
      transport 2-deoxyglucose than polyoma (Py)-transformed 3T3 cells. Py3T3 cells
      treated with dibutyryl cyclic adenosine 3'5' monophosphate (dBcAMP) and
      theophylline have reduced cell growth and transport 2-deoxyglucose at the same
      rate as normal 3T3 cells. Evidence that the cessation of cell growth and reduced
      transport abilities in Py3T3 cells does not represent a return to contact
      regulated growth comes from the following observations. First, treating high
      density Py3T3 cells with dBcAMP allows more than two doublings of cell number,
      even though ability to transport 2-deoxyglucose is returned to levels equal to
      those of normal 3T3 cells. Second, dBcAMP prevents serum-stimulated increases in
      2-deoxyglucose transport in Py3T3 but not in 3T3 cells.

PMID- 4345557
TI  - Chicken cardiac muscle: its elusive extended junctional sarcoplasmic reticulum
      and sarcoplasmic reticulum fenestrations.

PMID- 4345556
TI  - Secretion and endocytosis in insulin-stimulated rat adrenal medulla cells.
AB  - Insulin was used to deplete the adrenalin stores of rat adrenal medulla cells.
      Release of secretion was observed to occur by exocytosis. In addition, during the
      stages of massive release of secretory granules, the insulin-treated preparations
      showed greatly enhanced endocytic uptake of horseradish peroxidase. The tracer
      was taken up within vesicles, tubules, multivesicular bodies, and dense bodies.
      From acid phosphatase studies and from previous work it appears that many of the
      structures in which peroxidase accumulates are lysosomes or are destined to fuse
      with lysosomes. Subsequent to the period of intense exocytosis and endocytosis,
      there is a transient accumulation of lipid droplets in the adrenalin cells. The
      cells then regranulate, with new granules forming near the Golgi region. These
      results suggest that under the conditions used, much of the membrane that
      initially surrounds secretory granules is degraded after release of the granules.

PMID- 4345558
TI  - [Use of enzyme on the fluorometry for prostaglandins].

PMID- 4345559
TI  - Determination of vitamins D by gas-liquid chromatography. II. Rapid assay for
      vitamin  D2  in the presence of vitamin A and E.

PMID- 4345560
TI  - [A case of acute hemolytic anemia due to Clostridium perfringens A septicemia].

PMID- 4345561
TI  - Observations on the quantitative analysis of fatty acids in bovine blood serum.

PMID- 4345562
TI  - Investigation of the structure of a model iron-sulfur protein by spin and
      luminescence label methods.

PMID- 4345563
TI  - The origin of mitochondrial RNA of animal tissues studied by hybridization with
      mitochondrial DNA.

PMID- 4345564
TI  - EPR investigation of various nitroxide free radicals in biological and artificial
      membranes.

PMID- 4345565
TI  - Study of the kinetics of formation of ternary complex lactate dehydrogenase-NAD
      pyruvate.

PMID- 4345566
TI  - Huntington's chorea. Deficiency of gamma-aminobutyric acid in brain.

PMID- 4345567
TI  - Liver adaptation and injury in alcoholism.

PMID- 4345568
TI  - [Case records of the Massachusetts General Hospital. Weekly clinicopathological
      exercises. Case 7-1973].

PMID- 4345569
TI  - Therapeutic value of vitamin D metabolites.

PMID- 4345570
TI  - Hypothalamic regulatory hormones.
AB  - The molecular structures of several polypeptides isolated from hypothalamic
      tissue have been established and the synthesis of these compounds has been
      achieved. These polypeptides selectively stimulate or inhibit the release of
      anterior pituitary hormones and melanocyte-stimulating hormone. Various studies
      indicate their important physiological role and support the concept that some of
      these polypeptides are hormones. Some synthetic hypothalamic hormones and their
      derivatives may find important clinical and veterinary applications.

PMID- 4345571
TI  - Embryonic chick intestine in organ culture: response to vitamin D 3  and its
      metabolites.
AB  - Embryonic chick intestine maintained in organ culture responded to vitamin D(3)
      and its metabolites 25-hydroxycholecalciferol and 1,25-dihydroxycholecalciferol
      by synthesis of calcium-binding protein and enchanced calcium-45 uptake. The
      dihydroxy metabolite was by far the most potent inducer of the protein and also
      acted more rapidly than vitamin D(3) to stimulate isotope uptake. Despite its
      lower potency, vitamin D(3) itself was effective.

PMID- 4345572
TI  - [Functional state of the pituitary-adrenal system in stomach cancer].

PMID- 4345573
TI  - [Ultrastructural characteristics of human hepatocellular neoplasms].

PMID- 4345574
TI  - [Aldolase activity in human and animal tumors].

PMID- 4345575
TI  - [Morphology of bladder neoplasms induced by beta-naphthylamine in dogs].

PMID- 4345576
TI  - Bowel control.

PMID- 4345577
TI  - Suppression of periodic fever with estrogen.

PMID- 4345578
TI  - Respiration of homogenates and crude mitochondrial fractions of bovine attached
      gingiva.

PMID- 4345579
TI  - [Lymphography by means of "lymphoclysis" in post-thrombophlebitic ulcerative
      syndromes of the lower limbs].

PMID- 4345580
TI  - [The functional morphology of the thymus gland].

PMID- 4345581
TI  - [Agranulocytosis and toxic hepatic dystrophy during treatment with
      tuberculostatic drugs].

PMID- 4345582
TI  - [Morphologic characteristics of the functional state of the adrenals of animals
      in myocardial hypertrophy and decompensation].

PMID- 4345583
TI  - Composition and structure of the O-specific side chain of endotoxin from Serratia
      marcescens Bizio.

PMID- 4345584
TI  - Substrate stereochemical requirements in the reductive inactivation of uridine
      diphosphate galactose 4-epimerase by sugar and 5'-uridine monophosphate.

PMID- 4345585
TI  - Effects of photooxidation of histidine-38 on the various catalytic activities of
      glyceraldehyde-3-phosphate dehydrogenase.

PMID- 4345586
TI  - Effects of photooxidation of histidine-38 on the acetylphosphatase activity of
      glyceraldehyde-3-phosphate dehydrogenase.

PMID- 4345587
TI  - [The effect of Cl. perfringens type A toxin and its lethal lecithinase factor on
      the microcirculation].

PMID- 4345588
TI  - [Metabolism of individual phospholipid fractions in the brains of rats poisoned
      by phosphoorganic cholinesterase inhibitors].

PMID- 4345589
TI  - [Species specific and specific tumor antigens in the cells of interspecific
      somatic hybrids].

PMID- 4345590
TI  - [Effects of gamma radiation on the infectivity, antigenicity and immunogenicity
      of the foot-and-mouth disease virus].

PMID- 4345591
TI  - Comparison of a selective and a non-selective medium in the diagnosis of
      gonorrhoea to ascertain the sensitivity of Neisseria gonorrhoeae to vancomycin.

PMID- 4345592
TI  - Dynamic ultrastructure of presynaptic membranes at nerve terminals in the spinal
      cord of rats. Anesthetized and unanesthetized preparations compared.

PMID- 4345593
TI  - Centrifugal control of the avian retina. IV. Effects of reversible cold block of
      the isthmo-optic tract on the receptive field properties of cells in the retina
      and isthmo-optic nucleus.

PMID- 4345594
TI  - Intracellular study of the cat's primary auditory cortex.

PMID- 4345595
TI  - The role of acetylcholine in the intracerebellar nuclei of the cat.

PMID- 4345596
TI  - Anatomical studies of the organization of the spinal V nucleus: the deep bundles
      and the spinal V tract.

PMID- 4345597
TI  - [Effects of the intraventricular injection of 6-hydroxydopamine on the sleep
      waking cycle of the cat].

PMID- 4345598
TI  - The effects of reticular stimulation on the firing rate of neurons in the
      pericruciate cortex of cats.

PMID- 4345599
TI  - Electrophysiological properties of neuronal circuits in the frog cerebellum in
      vitro.

PMID- 4345600
TI  - Motor cortex modulation of knee flexor and extensor fusimotor neurons in the
      'pyramidal' cat.

PMID- 4345601
TI  - Neurochemical bases of the PGO wave.

PMID- 4345602
TI  - Dependence of REM sleep PGO waves on cholinergic mechanisms.

PMID- 4345603
TI  - Evidence of cholinergic mediation of ingestive responses elicited by
      dibutyryladenosine-3',5'-monophosphate in rat hypothalamus.

PMID- 4345604
TI  - Serotonin turnover in cultured raphe nuclei from newborn rat: in vitro
      development and drug effects.

PMID- 4345605
TI  - Infiltrating lobular carcinoma of the breast.

PMID- 4345606
TI  - Tumors of minor salivary origin. A clinicopathologic study of 492 cases.

PMID- 4345607
TI  - Mammary duct proliferation in the elderly. A histopathologic study.

PMID- 4345608
TI  - Familial occurrence of extramammary Paget's disease.

PMID- 4345609
TI  - Electrocoagulation and curettage for carcinoma involving the skin of the face,
      nose, eyelids, and ears.

PMID- 4345610
TI  - Adenocarcinoma of Bartholin's gland associated with Paget's disease of vulvar
      area.

PMID- 4345611
TI  - Carcinoma of large intestine in patients irradiated for carcinoma of cervix and
      uterus.

PMID- 4345612
TI  - Reappraisal of surgical management of sarcoma of the buttock.

PMID- 4345613
TI  - [New data on hormone-dependent hypertension and their significance for the
      practice].

PMID- 4345614
TI  - [Infectious mononucleosis. Determination of immunofluorescent antibodies against
      the Epstein-Barr virus and complement-fixation antibodies against the
      cytomegalovirus].

PMID- 4345615
TI  - A study of serum lipoprotein electrophoresis on cellogel: normal values,
      comparison with SML profiling and ultracentrifugation.

PMID- 4345616
TI  - Determination of serum guanase by means of a NADH-linked reaction.

PMID- 4345617
TI  - A non-mercurimetric automated method for serum chloride.

PMID- 4345618
TI  - Enzymatic determination of ammonia in blood plasma.

PMID- 4345619
TI  - [Comparison between radioimmunological and biological determination of plasma
      renin activity].

PMID- 4345620
TI  - The phospholipids of the thyroid gland.

PMID- 4345621
TI  - A short, retarded child with a deletion of the short arm of chromosome 18 (18p-).

PMID- 4345622
TI  - Ampicillin and hetacillin pharmacokinetics in normal and anephric subjects.

PMID- 4345623
TI  - Polygraphic study of dyssynergia cerebellaris myoclonica (Ramsay-Hunt syndrome)
      and of the intention myoclonus (Lance-Adams syndrome) during sleep.

PMID- 4345626
TI  - Determination of human chronological age by study of a collagen sample.

PMID- 4345624
TI  - Neuro-Behcet's syndrome in the United Arab Republic.

PMID- 4345625
TI  - An evaluation of the course of peripheral neuropathies based on clinical and
      neurographical re-examinations.

PMID- 4345627
TI  - Changes in collagen with age. IV. The extraction of soluble collagen from human
      lung.

PMID- 4345628
TI  - Intracisternal A-type and C-type particles observed in pulmonary tumors in mice.

PMID- 4345629
TI  - High yield of hepatic tumors in rats by cycasin.

PMID- 4345631
TI  - Serum glycoprotein levels in the rat bearing ascites hepatoma 109A.

PMID- 4345630
TI  - A hetero-organic antigen of a rat ascites hepatoma.

PMID- 4345632
TI  - An immuno-electron microscopic analysis of Epstein-Barr virus-related antigens in
      Burkitt lymphoma cells.

PMID- 4345633
TI  - [Combined dexamethasone suppression and chorionic gonadotrophin stimulation test
      in the diagnosis of androgenic functional ovarian tumors].

PMID- 4345634
TI  - Predicting the course of adenoid cystic carcinoma.

PMID- 4345635
TI  - [The dynamics of virus inactivation on surfaces in the aerosol method of
      contamination].

PMID- 4345636
TI  - [An experimental study of the viability of several viruses in meat products].

PMID- 4345638
TI  - Fine-needle aspiration biopsy of the liver in hepatic malignancy.

PMID- 4345639
TI  - Antimetabolites of coenzyme Q. 16. New alkylmercaptoquinones having antimalarial
      curative activity.

PMID- 4345637
TI  - The effect of hypertonic media on water permeability of frog urinary bladder.
      Inhibition by catecholamines and prostaglandin E 1 .
AB  - The frog urinary bladder undergoes, in some conditions, a marked increase of its
      water permeability when incubated in hypertonic media. This increase was observed
      with various nonpermeant solutes. It seems to result from the shrinkage of an
      osmo-sensitive compartment of the tissue, probably the epithelial cells. Many
      similarities were found between this effect and the physiological increase in
      water permeability (hydrosmotic response) elicited by antidiuretic hormone (ADH):
      both were dependent on the physiological state of the animals, and although the
      response was slower after hyperosmolar than after hormonal challenge, the
      patterns of response were similar, and in both cases markedly dependent on
      bathing solution temperature. Norepinephrine and prostaglandin E(1), which in
      this tissue reduce the hydrosmotic action of ADH, presumably by inhibiting the
      adenyl cylase also reduced the effect of hyperosmolarity. Conversely this effect
      was potentiated by incubation in the presence of oxytocin, exogenous cyclic AMP,
      and theophylline, conditions in which the intracellular concentration of cyclic
      AMP is increased. These data demonstrate that the response to hyperosmolarity is
      elicited, at least partly, by mechanisms also involved in the physiological
      hydrosmotic response to ADH.

PMID- 4345640
TI  - Isolation and renin-inhibitory activity of phosphoglyceride from shark kidney.

PMID- 4345641
TI  - A working hypothesis explaining the maintenance of the transformed state by SV40
      and polyoma.

PMID- 4345642
TI  - The prostatic cell DNA-steroid association: a hypothesis of nuclear events and
      cytoplasmic consequences.

PMID- 4345643
TI  - Instability of a layer of chemotactic cells, attractant and degrading enzyme.

PMID- 4345644
TI  - Oral carcinoma in the first three decades of life.

PMID- 4345645
TI  - Antibodies to EBV related antigens in West Malaysian children.

PMID- 4345646
TI  - Cellular and hormonal control in glycogen metabolism--recent advances.

PMID- 4345647
TI  - A case of glomus jugulare tumour.

PMID- 4345648
TI  - Electron microscopic studies on various types of inclusions found in autopsy
      cases. I. A new type of nuclear inclusion in the liver of polyradiculoneuritis.

PMID- 4345649
TI  - [Cytomegaly].

PMID- 4345650
TI  - Absorption of "penetrating" anions by hydrophobic parts of macromolecules.

PMID- 4345651
TI  - Investigation of the conformational properties of aspartate aminotransferase
      molecules by the spin-tag method.

PMID- 4345652
TI  - Investigation of photoprocesses in aromatic peptides by the method of electron
      paramagnetic resonance.

PMID- 4345653
TI  - Physical studies of membrane structure.

PMID- 4345654
TI  - Efficacy of psychiatric rehabilitation.

PMID- 4345655
TI  - [Activation of Na +  K +  ATPase of rat kidney microsomal fraction by
      angiotensin].

PMID- 4345656
TI  - [Current problems pertaining to the histochemistry of various normal and
      pathologic calcifying matrices].

PMID- 4345658
TI  - A theory and physical model for chochlear mechanics.

PMID- 4345657
TI  - Sleep and memory.
AB  - Two experiments demonstrated that memory over an interval with relatively high
      amounts of rapid eye movement (REM) sleep was inferior to memory over an interval
      with relatively high amounts of stage 4 sleep. The results suggest that, at least
      for humans, REM sleep does not facilitate memory consolidation and that stage 4
      sleep may be beneficial to memory.

PMID- 4345659
TI  - Tablet sensitivity testing: a comparison of different methods.

PMID- 4345660
TI  - Some characteristics of the A antigen in Marek's disease virus--infected cell
      cultures.

PMID- 4345661
TI  - A micro assay for mouse and human interferon.

PMID- 4345662
TI  - Fine structure of melanin-producing aeromonads.

PMID- 4345663
TI  - On the adsorption of Australia antigen to a colloidal silica, and some possible
      applications.

PMID- 4345664
TI  - Drug and sociotherapy in the aftercare of schizophrenic patients. One-year
      relapse rates.

PMID- 4345665
TI  - Faliure to demonstrate desmosterol in spinal fluid of brain tumor patients.

PMID- 4345666
TI  - Granular cells in tumors and in nontumorous tissue.

PMID- 4345667
TI  - Subacute sclerosing panencephalitis. Immunoultrastructural localization of
      measles-virus antigen.

PMID- 4345669
TI  - The "oxygenated complex" of cytochrome c oxidase.

PMID- 4345668
TI  - The effect of cholera toxin on the phosphorylation of protein in epithelial cells
      and their brush borders.

PMID- 4345670
TI  - Increases in rat liver cyclic AMP concentrations prior to the initiation of DNA
      synthesis following partial hepatectomy or hormone infusion.

PMID- 4345671
TI  - Kinetics of reconstitutioin of polyphenoloxidase from apoenzyme and copper.

PMID- 4345672
TI  - The identification and characterization of a cyclic AMP dependent protein kinase
      on rabbit reticulocyte ribosomes.

PMID- 4345673
TI  - Sialyl transferase activity in normal and RNA- and DNA-virus transformed cells
      utilizing desialyzed, trypsinized cell plasma membrane external surface
      glycoproteins as exogenous acceptors.

PMID- 4345674
TI  - The fluorescence behaviour of 1-anilino-8-naphthalene sulphonate in phospholipid
      and natural membranes.

PMID- 4345675
TI  - Isolated adrenal cortex cells: (Trp(Dnps) 9 )ACTH 5  -24 , an inhibitor of ACTH 1
      24 -induced cyclic AMP and corticosterone production.

PMID- 4345676
TI  - Transmural and subcellular localization of monoamine oxidase and catechol-0
      methyl transferase in rabbit aorta.

PMID- 4345677
TI  - Interaction of chloropromazine with adrenochrome and interference of a possible
      endogenous psychotogenic agent with some synaptic enzyme activities.

PMID- 4345678
TI  - Isolation and identification of a renin inhibitor form ox bile.

PMID- 4345679
TI  - [Neurologic disorders caused by ossification of the ligamenta flava of the
      thoracic spine; analysis of x-ray picture and diagnostic significance].

PMID- 4345680
TI  - [Cyclic AMP and malignant glioma. 1. Effects of dibutyryl adenosine cyclic 3',5'
      monophosphate on malignant glioma cells].

PMID- 4345681
TI  - [Structural transitions in a complex of RNA polymerase from Escherichia coli B
      with T2 DNA].

PMID- 4345682
TI  - [Spontaneous impulse activity of visual cortex neruons during asphyxia in
      animals].

PMID- 4345683
TI  - [Neuronal activity of the caudal mesenteric sympathetic ganglion].

PMID- 4345684
TI  - [Suprasegmental synaptic influences on the lumbar motor neurons of turtles].

PMID- 4345685
TI  - Assisting patients with posthospitalization plans.

PMID- 4345686
TI  - Coupled layers: a new technique for the two-dimensional thin-layer chromatography
      of carbohydrates.

PMID- 4345687
TI  - [Quantitative analysis of catecholamine and serotonin metabolites on thin-layer
      plates. II. Reflectance measurements after a specific photochemical reaction].

PMID- 4345688
TI  - [Thin layer chromatographic identification of organic acids previously separated
      quantitatively on silica gel columns].

PMID- 4345689
TI  - A method for the determination of Venzar (3-cyclohexyl-5,6-trimethyluracil) on
      silica gel layers.

PMID- 4345690
TI  - Effect of upright posture and isoproterenol infusion on cyclic adenosine
      monophosphate excretion in control subjects and patients with labile
      hypertension.

PMID- 4345691
TI  - Lack of responsiveness to L-dopa in Cushing's disease.

PMID- 4345692
TI  - Control of hypoglycemia with L-asparaginase in a patient with islet cell cancer.

PMID- 4345694
TI  - Control of aldosterone secretion in hyperthyroidism.

PMID- 4345693
TI  - Peroxidase defect in congenital goiter with complete organification block.

PMID- 4345695
TI  - Serotonin and inhibition in Limulus lateral eye.
AB  - The response to light of one ommatidium is reduced or suppressed by simultaneous
      illumination of neighboring ommatidia. The mechanism of this lateral inhibition
      may be chemical synaptic transmission, based on the physiological findings of a
      number of investigators and on the following evidence. The fine structure of the
      neuropil of the lateral plexus exhibits numerous clear vesicles (ca. 400 A),
      dense-core vesicles (ca. 700-1400 A), Golgi regions, and other morphological
      features of neurochemical synapses. The indolealkylamine, serotonin (5-HT), even
      in nanomolar concentrations, has a potent inhibitory action. An initial, potent
      inhibitory dose of 5-HT produces a long lasting densensitization to subsequent
      doses. The desensitization affects lateral inhibition evoked by light stimulation
      of neighboring receptors, i.e. crossed-desensitization. Eye tissue extracts
      contain 5-HT and melatonin (MLT) at a level greater than 1 microg/g wet tissue
      and perhaps as high as 20-30 microg/g, as determined by two-dimensional thin
      layer chromatography (TLC) and o-phthaldialdehyde fluorescence assay techniques.
      Subcellular fractionation on sucrose gradient indicates a peak in 5-HT and MLT
      content associated with an intermediate density fraction. 5-HT may be an
      inhibitory transmitter for lateral inhibition. One pathway for metabolism of 5-HT
      in the lateral eye may be via N-acetylserotonin and melatonin.

PMID- 4345696
TI  - Thickness and area measurements as parameters of skeletal involution of the
      humerus, femur, and tibia.

PMID- 4345697
TI  - Relationship of radiographic cortical thickness vs. age in thirteen bones of the
      hand.

PMID- 4345698
TI  - Studies on nitroxide spin-labeled poly- -benzyl- ,L-glutamate.

PMID- 4345699
TI  - Follow-up care after hospitalization. Health center vs hospital.

PMID- 4345700
TI  - [The part played by adrenergic receptors in the effect of glucocorticoids on the
      cardiovascular system].

PMID- 4345701
TI  - Effects of dibutyryl cyclic adenosine phosphate plus theophylline on murine
      sarcoma virus transformed non-producer cells.

PMID- 4345702
TI  - Some aspects of the tubular locus of the natriuretic action of vasoactive drugs.

PMID- 4345703
TI  - Induction of antinuclear antibodies in (CxB6) F1 mice inoculated with Graffi and
      Rauscher leukemogenic viruses.

PMID- 4345704
TI  - Herpes simplex virus replication in human lymphocyte cultures stimulated with
      phytomitogens and anti-lymphocyte globulin.

PMID- 4345705
TI  - Study of immune cytotoxicity with Herpesvirus hominis infected cells.

PMID- 4345706
TI  - Interferon induction in normal leukemic human lymphocyte cultures by tilorone
      hydrochloride.

PMID- 4345707
TI  - Variations in the interferogenic responses of two strains of mice.

PMID- 4345708
TI  - The form of absorption of lipids in the chicken, Gallus domesticus.

PMID- 4345709
TI  - Heterogeneity of human plasma high density lipoprotein.

PMID- 4345710
TI  - Roles of aortic and carotid chemoreceptors in activating the hypothalamo
      hypophyseal-adrenocortical system during hypoxia.

PMID- 4345711
TI  - Comparative effects of hypoxia, adrenocorticotropin and methylcholine on
      adrenocortical secretory rates.

PMID- 4345712
TI  - Effect of methylprednisolone in epinephrine-thyroxine induced arteriosclerosis.

PMID- 4345713
TI  - Interferon inhibition by narcotic analgesics.

PMID- 4345714
TI  - Blocking of interferon production by chromatographically purified L cell
      interferon.

PMID- 4345715
TI  - A simple method for the growth of mouse neuron monolayer cultures.

PMID- 4345716
TI  - Effect of a converting enzyme inhibitor (SQ 20,881) on angiotensin-induced
      drinking.

PMID- 4345718
TI  - Inhibition of protocollagen proline hydroxylase by Dilantin.

PMID- 4345717
TI  - Adipose and liver tissue enzyme profiles in obese hyperglycemic mice.

PMID- 4345719
TI  - Interferon antagonists induced by Newcastle disease virus (NDV).

PMID- 4345720
TI  - Differentiation of types 1 and 2 herpes simplex virus by plaque inhibition with
      sulfated polyanions.

PMID- 4345721
TI  - Binding of angiotensin I and angiotensin II to plasma proteins precipitated by
      ammonium sulfate.

PMID- 4345722
TI  - The role of angiotensin II in a pressor response to nicotine after
      phenoxybenzamine.

PMID- 4345723
TI  - Stimulation of angiotensinogen formation by renin and angiotensin.

PMID- 4345724
TI  - The production of human leukocyte interferon in a serum-free medium.

PMID- 4345725
TI  - Interferon and cell division. VII. Inhibitory effect of highly purified
      interferon preparations on the multiplication of leukemia L 1210 cells.

PMID- 4345726
TI  - Histochemical study of the effect of a deuteron beam on the dental germ.

PMID- 4345727
TI  - In vitro evaluation of enzymatic debridement of burn wound eschar.

PMID- 4345728
TI  - Aspiration cytology in carcinoma of the pancreas.

PMID- 4345729
TI  - The effect of ACTH on corticosteroid concentration in monkey bile, as measured by
      competitive protein-binding analysis.

PMID- 4345730
TI  - A summary of the status of de novo cancer in transplant recipients.

PMID- 4345732
TI  - Liver transplantation.

PMID- 4345733
TI  - [Biochemical and ultrastructural study of bronchial carcinoids].

PMID- 4345731
TI  - Personal experience with orthotopic liver transplantation.

PMID- 4345734
TI  - [Electron microscopic study of viral particles in the pancreas of normal and
      leukemic mice].

PMID- 4345735
TI  - [Effect of polymyxin on the sensitizing and reactive properties of pertussis
      vaccine].

PMID- 4345736
TI  - Cyclic AMP in the regulation of gastric secretion in dogs and humans.

PMID- 4345738
TI  - Reinforcement of reflex epinephrine release by angiotensin II.

PMID- 4345737
TI  - Amino acid transport in bone: stimulation by cyclic AMP.

PMID- 4345739
TI  - Carboxylate modification of neuromuscular transmission in the frog.

PMID- 4345740
TI  - [Vascularization of the multiforme glioblastoma].

PMID- 4345741
TI  - [Renal changes in experimental hyperaldosteronism. Histochemical and
      ultrastructural study].

PMID- 4345743
TI  - A comparison of influenza and parainfluenza and RNP properties.

PMID- 4345742
TI  - Induction of interferon and host resistance in vivo by double-stranded complexes
      of copolyribonucleotide of isosinic and guanylic with polyribocytidylic acid.

PMID- 4345744
TI  - Responses of isolated monkey umbilical veins to biogenic amines and polypeptides.

PMID- 4345745
TI  - Action of angiotensin and plasmakinins on blood flow through the mammary artery
      in lactating small ruminants.

PMID- 4345746
TI  - [Clinico-functional results of synovectomy of the knee].

PMID- 4345747
TI  - (2- 14 C) ethanol as a precursor of glutamine, glutamate, -aminobutyric acid and
      aspartate in hamster brain in vivo.

PMID- 4345749
TI  - [Diagnosis of malignant stomach tumors].

PMID- 4345748
TI  - Mode of action of 5,5'-diphenylthiohydantoin-sites of action of 5,5'
      diphenylthiohydantoin in mitochondria in relationship to thyroxine-stimulated
      responses.

PMID- 4345750
TI  - Significance of the LP-X test in differential diagnosis of jaundice.

PMID- 4345751
TI  - [Internal distribution of silicon after intraperitoneal administration of sodium
      silicate].

PMID- 4345752
TI  - Effect of diazoxide on golden hamsters with chronic hypoglycemia due to a
      transplantable islet-cell tumor.

PMID- 4345753
TI  - The influence of blood glucose on ACTH secretion in man.

PMID- 4345754
TI  - Effects of metopirone on urinary excretion of adrenaline, noradrenaline and
      vanylmandelic acid in different physiological conditions. The possible role of
      adrenal cortex in catecholamine degradation.

PMID- 4345755
TI  - On the effect of synthetic LH-releasing hormone on the blood levels of LH, FSH,
      HGH, TSH, ACTH, insulin and blood sugar in man.

PMID- 4345756
TI  - Calcitonin secretion in medullary carcinoma of the thyroid.

PMID- 4345757
TI  - The formation and distribution of cyclic 3',5'-adenosine monophosphate in the
      everted guinea pig seminal vesicle sac.

PMID- 4345758
TI  - Virus-induced genitourinary malignancy. Macromolecular identity.

PMID- 4345759
TI  - Laboratory production and  14 C-labelling of viomycin.

PMID- 4345760
TI  - Petrographic study of the refractory performance of high-fusing dental alloy
      investments. I. High-fired, phosphate-bonded investments.

PMID- 4345761
TI  - Regulation of insulin secretion in the ovine foetus in utero. Effects of sodium
      valerate on secretion and of adrenocorticotrophin-induced premature parturition
      on the insulin secretory response to glucose.

PMID- 4345762
TI  - Lipolysis and adenosine 3',5'-cyclic monophosphate in adipose tissue of the New
      Zealand obese mouse.

PMID- 4345763
TI  - Effect of sleep on memory. 3. Controlling for time-of-day effects.

PMID- 4345764
TI  - The hyperphosphatemic effect of disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP
      TM ): renal handling of phosphorus and the renal response to parathyroid hormone.

PMID- 4345765
TI  - The pathology and immunology of Bordetella pertussis infection.

PMID- 4345766
TI  - The prevention of experimental Clostridium novyi and Cl. perfringens gas gangrene
      in high-velocity missile wounds by active immunisation.

PMID- 4345767
TI  - The effect of the medium and source of growth factors on the satellitism test for
      Haemophilus species.

PMID- 4345769
TI  - The epidemiology of tanapox and yaba virus infections.

PMID- 4345768
TI  - An electron-microscopic study of intracerebral infection of mice with low
      virulence Bordetella pertussis.

PMID- 4345770
TI  - Steroid metabolism in the adrenals of fetal sheep in relation to natural and
      corticotrophin-induced parturition.

PMID- 4345771
TI  - Parturition in the goat and sheep: changes in corticosteroids, progesterone,
      oestrogens and prostaglandin F.

PMID- 4345772
TI  - The physiological roles of progesterone, oestradiol-17  and prostaglandin F 2  
      in the control of ovine parturition.

PMID- 4345773
TI  - [Aging of articular cartilage and arthrosis].

PMID- 4345774
TI  - [An experiment in treatment by rehabilitation methods for purposes of relaxation
      applied to patients with functional diseases at work (apropos of 100 cases)].

PMID- 4345775
TI  - [Bithalamic tumor. 2 anatomoclinical cases in Negroes].

PMID- 4345776
TI  - [Case of thesaurismosis caused by polyvinylpyrrolidone (P.V.P.)].

PMID- 4345777
TI  - [Fever in cancer patients, a symptom which should not be neglected].

PMID- 4345778
TI  - [Retrospective study of cancer in the aged in the population of an anti-cancer
      center].

PMID- 4345779
TI  - [Effect of hydrocortisone and insulin on the activity of fructose-1,6
      diphosphatase in liver tissue during carcinogenesis].

PMID- 4345781
TI  - [Blood serum lipids and post--heparin lipolytic activity during exacerbation of
      chronic pancreatitis].

PMID- 4345780
TI  - [Role of cyclic adenosine-3',5'-monophosphate in the induction of
      guanidinoacetate-N-methyltransferase in rat pancreas].

PMID- 4345782
TI  - [Hexokinase activty in human brain tumors].

PMID- 4345783
TI  - [Monoamine oxidase activity of the blood in metabolic-alimentary obesity].

PMID- 4345784
TI  - [Erythrocyte enzymes and substrates in children with Down's syndrome].

PMID- 4345785
TI  - [Measurement of tension using piezoelectric force recorders].

PMID- 4345787
TI  - Determination of N-(9-( -D-ribofuranosyl)purin-6-ylcarbamoly)threonine at the
      picomole level in transfer-RNA.

PMID- 4345786
TI  - Chronic active hepatitis and Graves' disease.

PMID- 4345788
TI  - Determination of steady-state concentrations of adenine nucleotides in growing C.
      kluyveri cells by biosynthetic labeling.

PMID- 4345789
TI  - Advantages of the use of Cerenkov vounting for determination of P 32  in
      photophosphorylation research.

PMID- 4345790
TI  - Method for rapid isolation of free aminoacyl-transfer RNA.

PMID- 4345791
TI  - Agarose gel electrophoresis of serum lipoproteins: determination of true
      mobility, isoelectric point, and molecular size.

PMID- 4345792
TI  - Simple and sensitive photometric recycling assay for nicotinamide-adenine
      dinucleotide.

PMID- 4345793
TI  - [Electronic EMG evaluation in facial hemispasm].

PMID- 4345795
TI  - [Recruitment. Comparison of test methods with special reference to the stapedius
      reflex test].

PMID- 4345794
TI  - [Taste examination in neuro-otological patients].

PMID- 4345796
TI  - [Critical comments on the so-called Metz recruitment].

PMID- 4345797
TI  - [Follow-up results in acute isolated vestibular disorders (vestibular
      neuronopathy)].

PMID- 4345798
TI  - [Phases of spontaneous transitory activation during normal sleep in humans].

PMID- 4345799
TI  - [Study of the covariation of electroencephalographic, motor and cardiac variables
      during night sleep in humans].

PMID- 4345800
TI  - [Reduction-oxidation and hydrolytic enzymes in gastric cancer and its
      metastases].

PMID- 4345801
TI  - The effect of cyclic adenosine- and guanosine 3',5'-monophosphate on the normal
      and drug-increased coronary blood flow.

PMID- 4345802
TI  - Phosphodiesterase inhibition by papaverine and structurally related compounds.

PMID- 4345803
TI  - Butyl isocyanate, an active-site-specific reagent for yeast alcohol
      dehydrogenase.

PMID- 4345804
TI  - Transcription of ribonucleic acid by the ribonucleic acid directed
      deoxyribonucleic acid polymerase of Rous sarcoma virus and deoxyribonucleic acid
      polymerase I of Escherichia coli.

PMID- 4345806
TI  - Heterogeneity of human plasma very low density lipoproteins. Separation of
      species differing in protein components.

PMID- 4345805
TI  - Purification and kinetic properties of Neurospora transfer ribonucleic acid
      nucleotidyltransferase.

PMID- 4345807
TI  - The role of phospholipid in succinate cytochrome c reductase.

PMID- 4345808
TI  - Phosphate transfer from adenosine triphosphate in a model system.

PMID- 4345809
TI  - Tissue reactions to the three root canal medicaments.

PMID- 4345810
TI  - Sendai (parainfluenza 1) infection of mouse eggs.

PMID- 4345811
TI  - The effects of polyvinyl pyridine-N-oxide (P204) on the cytopathogenic action of
      chrysotile asbestos in vivo and in vitro.

PMID- 4345812
TI  - A quantitative investigation of the effects on the growth of calcium oxalate
      crystals on potential inhibitors.

PMID- 4345813
TI  - Biochemical changes in intestinal mucosa after experimental small bowel by-pass
      in the rat.

PMID- 4345814
TI  - Pressor response to angiotensin I and angiotensin II: the site of conversion of
      angiotensin I.

PMID- 4345815
TI  - Protocollagen proline hydroxylase in the eye, cartilage and skin of chicken
      embryo.

PMID- 4345817
TI  - [Causes and clinical symptoms of nerve injuries].

PMID- 4345816
TI  - Immunofluorescence for routine diagnosis of respiratory syncytial virus
      infection.
AB  - A comparison of immunofluorescent tests for the diagnosis of respiratory
      syncytial (RS) virus infections was carried out on 42 hospitalized cases of
      respiratory infection in childhood. Respiratory syncytial virus was detected in
      22 (52%) cases, the most sensitive method of detection being by indirect
      immunofluorescence of Bristol HeLa tissue cultures inoculated with nasopharyngeal
      aspirates. The highest detection rate was in bronchiolitis cases (92%). Detection
      of antibody rises in paired sera, eight days apart, confirmed RS virus infection
      in 13 of 16 cases, the most sensitive test being detection of a specific rise in
      IgG antibody by indirect immunofluorescence. A serodiagnosis was made in all 10
      non-bronchiolitis cases. Recommendations are made for the application
      ofimmunofluorescence to routine diagnosis of RS virus infection.

PMID- 4345818
TI  - [Operative reconstruction of injured nerves].

PMID- 4345819
TI  - [Operative reconstruction of injured nerves].

PMID- 4345820
TI  - [Reconstructive surgery in irreparable paralyses of peripheral nerves].

PMID- 4345821
TI  - [Round-table discussion on the topic: peripheral nerve injuries].

PMID- 4345822
TI  - [Simultaneous incidence of Australia (SH) antigen and complement binding
      antibodies against Cytomegalovirus in blood donors in Hamburg].

PMID- 4345823
TI  - [Intracranial tumors in mentally ill patients].

PMID- 4345824
TI  - Electron spin resonance study of radicals produced by one-electron reduction of
      pyridines.

PMID- 4345825
TI  - [Diagnostic problems connected with isolation of 2 different enteroviruses from
      the same patient].

PMID- 4345826
TI  - [Study of the multiplication, in cell cultures, of 2 strains of parainfluenza
      virus of type 3. I. Multiplication in KB cell line].

PMID- 4345827
TI  - [Experimental herpetic infection in newborn rats. II. Dynamics of the
      histopathological changes].

PMID- 4345828
TI  - [Possible relationships between herpes viruses and some tumors].

PMID- 4345829
TI  - Antitumor activity of polyinosinic-polycytidylic acid in combination with some
      biologically active compounds.

PMID- 4345830
TI  - Differences in the primary structure of nucleolar and ribosomal high molecular
      weight RNA of the novikoff hepatoma and rat liver, and possible therapeutic
      implications.

PMID- 4345831
TI  - Relations between metabolic increase of plasma free fatty acids and the
      occurrence of arteriosclerotic thromboarteritis in rabbits.
AB  - Rabbits maintained for several weeks on a regimen of modest amounts of vitamin D
      and dietary cholesterol were placed in three groups in accordance with their
      response to repeated subcutaneous injections of nicotine in mineral oil. The
      group that had the greatest increase in plasma FFA following nicotine injections
      gradually developed, over a period of about 12 weeks, severe calcific
      atheroarteriosclerosis with peripheral thromboarteritis. Those that had a
      moderate increase in plasma FFA following nicotine injections developed calcific
      atheroarteriosclerosis but no thromboarteritis. Those that had the least increase
      in plasma FFA following nicotine injections developed no arterial lesions.
      Comparable or much greater increases in plasma FFA occurred in rabbits on the
      vitamin D-cholesterol regimen when adrenalin, ACTH or heparin was injected rather
      than nicotine. These animals did not develop calcific atheroarteriosclerotic
      thromboarteritis or any other lesions which could be correlated with the
      increased levels of plasma FFA. Inasmuch as nicotine, vitamin D or dietary
      cholesterol in the amounts used were innocuous when used alone, the interactions
      between the effects of at least these three factors need to be known in
      individual animals before the pathogenesis of the calcific atheroarteriosclerotic
      lesions with thrombosis can eventually be understood.

PMID- 4345832
TI  - Plasma renin activity and blood pressure in 89 patients receiving maintenance
      haemodialysis therapy.
AB  - Blood pressure, plasma renin activity, plasma sodium concentration, plasma
      potassium concentration, dietary sodium intake, and duration of dialysis have
      been measured under standard conditions in 89 patients on maintenance
      haemodialysis. No significant relation was found between plasma renin activity
      and blood pressure. Statistically significant correlations were found between
      plasma renin activity and plasma sodium concentration and between plasma renin
      activity and dietary sodium intake.Only one patient was found to have
      uncontrollable hypertension associated with a markedly raised plasma renin
      activity. Reasons are given for not performing bilateral nephrectomy in this
      patient. We believe the low incidence of uncontrollable hypertension and
      hyperreninaemia in our patients to be due to their slow introduction to
      haemodialysis, thus preventing violent swings in body weight, blood pressure, and
      renin secretion.Although plasma renin activity did fall with duration of
      dialysis, all 15 patients who have been on maintenance dialysis for longer than
      five years have normal levels.

PMID- 4345834
TI  - A serologic survey of veterinarians for antibody to feline leukemia virus.

PMID- 4345833
TI  - Nuclear magnetic resonance studies of rat serum lipoproteins.

PMID- 4345835
TI  - Synopsis of vaccination procedures for dogs.

PMID- 4345836
TI  - Oxidative phosphorylation in mitochondria during embryonic development.

PMID- 4345837
TI  - [Effect of preliminary treatment with carbon monoxide on the development of
      hypokinetic disorders in albino rats].

PMID- 4345838
TI  - Changes in plasma insulin during ethanol-induced hypoglycemia.

PMID- 4345839
TI  - Thiazide diuretics and calcium metabolism.

PMID- 4345840
TI  - [Bilateral Wilms' tumor in-two and one-half year old girl].

PMID- 4345841
TI  - The effect of initial age on the response of the rat to treatment with
      gonadotrophins.

PMID- 4345842
TI  - The effect of initial body weight on the response of the rat to treatment with
      gonadotrophins.

PMID- 4345843
TI  - Response of plasma aldosterone to angiotensin II, ACTH and potassium in man.

PMID- 4345844
TI  - Familial poly-endocrinopathy.

PMID- 4345845
TI  - [An unusual neurological form of fascioliasis caused by Fasciola hepatica in a
      child].

PMID- 4345846
TI  - [Electron spin resonance in neoplasm research].

PMID- 4345847
TI  - Respiration of homogenates and mitochondrial fractions of bovine dental pulp.

PMID- 4345848
TI  - Cell biology of the mycoplasmas.

PMID- 4345850
TI  - Genetics of human-mouse somatic cell hybrids: linkage of human genes for
      isocitrate dehydrogenase and malate dehydrogenase.

PMID- 4345851
TI  - Mitochondrial polymorphism. IV. Phospholipid composition of mitochondria of a
      wheat hybrid and its parents.

PMID- 4345852
TI  - Determination of adenosine 3':5'-cyclic monophosphate in cerebral tissues by
      saturation analysis. Assessment of a method using a binding protein from ox
      muscle.
AB  - 1. The Gilman (1970) procedure for determining cyclic AMP (adenosine 3':5'-cyclic
      monophosphate) by saturation analysis gave erroneous results when applied to the
      analysis of extracts of whole brain or preparations of membrane fragments from
      brain. 2. The extracts contained a non-diffusible factor, which enhanced the
      binding of cyclic AMP by the muscle protein fraction. 3. Extracts also contained
      material which inhibited binding, but net inhibition of binding was only observed
      when relatively concentrated extracts were analysed. 4. The error introduced by
      the factors modifying binding could be eliminated by incorporation of unlabelled
      internal standards in the unknowns. The design adopted enables a statistical
      estimate to be made of the standard error of a single assay. 5. The modified
      assay was used to determine bound cyclic AMP and adenylate cyclase activity in
      cerebral membrane fragments. Five preparations of synaptic membrane fragments
      contained less than 3.5pmol of cyclic AMP/mg of protein; a microsomal fraction
      from rat contained 65pmol of cyclic AMP/mg of protein.

PMID- 4345853
TI  - A heat-stable nicotinamide-adenine dinucleotide glycohydrolase from Pseudomonas
      putida KB1. Partial purification and some properties of the enzyme and an
      inhibitory protein.
AB  - A thermostable NAD(P)(+) glycohydrolase (EC 3.2.2.6) detected in cell-free
      extracts of Pseudomonas putida KB1 was purified to a single component on
      polyacrylamide-gel electrophoresis. A heat-labile inhibitor of the enzyme was
      also partially purified. Enzyme free of inhibitor is present in culture
      supernatants. After an ultrasonic treatment enzyme-inhibitor complex and excess
      of inhibitor are present in both the cell-debris and soluble fractions. The
      general properties of the enzyme and inhibitor are described. The molecular
      weights of enzyme, inhibitor and enzyme-inhibitor complex, determined by gel
      filtration are about 23500, 15000 and 35000 respectively. The binding of
      inhibitor and enzyme is inhibited by the presence of substrate.

PMID- 4345854
TI  - The structure of a glycerylphosphoryldiglucosyl diglyceride from the lipids of
      Acholeplasma laidlawii strain B.
AB  - 1. The phosphatidylglucose structure proposed previously (Smith & Henrikson,
      1965) for the glucose-containing phospholipid from Acholeplasma laidlawii is
      incorrect. 2. The structure now proposed is 3-(sn-glycerol-3-phosphoryl-6'-[O
      alpha-d-glucopyranosyl-(1-->2)-O-alpha-d-glucopyranosyl])- sn-1,2-diglyceride, a
      new type of bacterial lipid. 3. Deacylation of the lipid gave a single water
      soluble phosphate ester which could be distinguished on chromatography from
      synthetic samples of glucosylphosphorylglycerols. 4. Hydrolysis of the lipid with
      alkali gave a mixture of fatty acids, glycerol 2-phosphate, sn-glycerol 3
      phosphate and O-alpha-d-glucopyranosyl-(1-->2)-O-alpha- d-glucopyranosyl-(1-->1)
      d-glycerol. 5. The lipid was unaffected on incubation with phospholipases A, C
      and D. 6. Diglucosyl diglyceride was isolated after treatment of the lipid with
      60% HF, establishing the location of the fatty acid residues. 7. Periodate
      oxidation studies showed that the sn-glycerol 3-phosphate was esterified to the 6
      hydroxyl group of one of the glucose residues in diglucosyl diglyceride.

PMID- 4345849
TI  - Molecular structure of bacterial plasmids.

PMID- 4345855
TI  - The polyamine content in two slow-growing rat hepatomas.

PMID- 4345856
TI  - The chemistry of the collagen cross-links. A convenient synthesis of the
      reduction products of several collagen cross-links and cross-link precursors.
AB  - New synthetic routes to the reduction products of several collagen cross-links
      and cross-link precursors are described. By the use of these routes
      hydroxynorleucine, 5,6-dihydroxynorleucine, hydroxylysinonorleucine and
      hydroxylysinohydroxynorleucine can be synthesized via one common synthetic
      intermediate. The synthetic routes provide a convenient source of these unusual
      amino acids, as well as confirming the structure of
      hydroxylysinohydroxynorleucine and the other lysine-derived residues found in
      borohydride-reduced collagens.

PMID- 4345857
TI  - Effect of oxidative phosphorylation inhibitors on cyclic adenosine monophosphate
      synthesis in rat adipose tissue.

PMID- 4345858
TI  - Biochemical lesion in rat liver mitochondria induced by hexachlorophene.

PMID- 4345859
TI  - 1-Ethyl-4-(isopropylidenehydrazino)-1H-pyrazolo-(3,4-b)-pyridine-5-carboxylic
      acid, ethyl ester, hydrochloride (SQ 20009)--a potent new inhibitor of cyclic
      3',5'-nucleotide phosphodiesterases.

PMID- 4345860
TI  - Control of prostaglandin biosynthesis in rat brain homogenates by adenine
      nucleotides.

PMID- 4345861
TI  - Metabolic action of urethan on protein synthesis and drug oxidation in normal and
      regenerating liver.

PMID- 4345862
TI  - Cyclic 3',5'-adenosine monophosphate response in the rabbit lung--adult
      properties and development.

PMID- 4345863
TI  - [Minor role of the de novo pathway in the biosynthesis of RNA during fetal and
      neoplastic liver development in rats].

PMID- 4345864
TI  - NaF inhibition of phosphorylation and dephosphorylation involved in  -methyl-D
      glucoside transport in E. coli K 12. A pH dependant phenomenon sensitive to
      uncoupling agents.

PMID- 4345865
TI  - [Synthesis of protoheme by the yeast Saccharomyces cerevisiae. II. Effects of
      glucose on respiratory adaptation].

PMID- 4345866
TI  - On the determination of the molecular weight of lactate dehydrogenase by gel
      filtration on Sephadex G-200.

PMID- 4345867
TI  - Inheritance of syndactyly.

PMID- 4345868
TI  - Changes of blood pressure, renin, and angiotensin after bilateral nephrectomy in
      patients with chronic renal failure.
AB  - Circulating levels of renin, angiotensin I, and angiotensin II were increased in
      six patients with chronic renal failure and hypertension uncontrolled by dialysis
      and hypotensive drugs. Lower and often normal levels were found in 10 patients
      whose blood pressure was controlled by dialysis treatment. For a variety of
      reasons all patients were subjected to bilateral nephrectomy. The logarithm of
      the decrease in plasma concentrations of renin and angiotensin II was
      significantly related to the fall of blood pressure after operation. Plasma renin
      concentration correlated significantly with blood angiotensin I concentration and
      with plasma angiotensin II in samples taken before and after nephrectomy. Renin,
      angiotensin I, and angiotensin II were measurable in samples of blood taken 48
      hours or more after the operation.

PMID- 4345869
TI  - Follow-up of hydatidiform mole by radioimmunoassay of human chorionic
      gonadotrophin.
AB  - An improved method for the follow-up of patients delivered of a hydatidiform mole
      using radioimmunoassay of human chorionic gonadotrophin is employed to ensure
      adequate sensitivity. Four illustrative case histories are described. Their HCG
      findings are presented to show that this is the principal basis on which
      decisions should be made.There are three aspects to the work of the laboratory.
      The technical work of the assay, the clerical effort of patient follow-up, and
      the clinical interpretation of results. The laboratory keeps a close check on
      follow-up (one of its most important functions) and receives specimens direct
      from patients. Overall control of all three aspects is by a clinician. It has
      been found useful to organize a special clinic for these patients to be seen. In
      this region it has been possible for this to be run by the same clinician.

PMID- 4345870
TI  - Kinetic measurements with monocarboxylic acids as substrates and effectors of
      glutamate dehydrogenase.

PMID- 4345871
TI  - Interaction of hydrogen peroxide with superoxide dismutase from erythrocytes.

PMID- 4345872
TI  - Myeloproliferative disease in a turtle.

PMID- 4345873
TI  - Morbidity in post-myelogram patients--a survey of 100 patients.

PMID- 4345874
TI  - Congenital syphilitic deafness.

PMID- 4345876
TI  - Adolescent anorexia nervosa: the patient; an approach.

PMID- 4345875
TI  - Instant pudding.

PMID- 4345877
TI  - Trends in psychiatric care in Europe.

PMID- 4345878
TI  - The financial plight of the elderly.

PMID- 4345879
TI  - Hydrotherapy--is it all washed up?

PMID- 4345880
TI  - Nursing management of feelings, thoughts and behavior.

PMID- 4345881
TI  - [Mitochondrial crystals in a metastatic carcinoma of the choroid].

PMID- 4345882
TI  - [Factors in post treatment recurrence of pulmonary tuberculosis].

PMID- 4345883
TI  - [Treatment of climacteric disorders. Clinical results].

PMID- 4345884
TI  - Rehabilitation and health visitor follow-up.

PMID- 4345885
TI  - [Treatment and prognosis of Wilm's tumor].

PMID- 4345886
TI  - [Radiologic examination of sciatic nerves. Radiculography].

PMID- 4345888
TI  - [Practical medicine and syndactylia].

PMID- 4345887
TI  - [Sciaticas due to other causes than a herniated disk].

PMID- 4345889
TI  - [Immunization of pigs against swine pox with culture-adapted virus].

PMID- 4345890
TI  - Malignant nonchromaffin paraganglioma.

PMID- 4345891
TI  - Electron paramagnetic resonance studies on the selenium-replaced derivatives of
      adrenodoxin: the presence of the one selenium-one sulfur compound.

PMID- 4345892
TI  - Hormone-treated CHO cells exit the cell cycle in the G2 phase.

PMID- 4345894
TI  - The effect of hydration of lecithin-water lamellar phases: a comparative study of
      solute diffusion and ESR spectroscopic measurements.

PMID- 4345893
TI  - Cycl AMP in Gl-arrested BHK21 cells infected with adenovirus type 12.

PMID- 4345895
TI  - Isolation and preliminary characterization of corticosterone-receptor complexes
      in mouse placental tissue.

PMID- 4345896
TI  - Effect of glycolysis inhibitors on cyclic AMP synthesis in rat adipose tissue.

PMID- 4345897
TI  - Partial purification and characterization of a renin-like enzyme from rat
      submandibular gland.

PMID- 4345898
TI  - [Eosinophilic leukemia, an immature cell myelosis with chloroacetate esterase
      positive eosinophilia. A morphological and cytochemical study on the problem of
      monophylic myeloses].

PMID- 4345899
TI  - Effects of acute hypocapnia and hypercapnia on neuromuscular transmission and on
      monosynaptic spinal reflex in wakeful man.

PMID- 4345900
TI  - The "wheat-stubble sarcoid granuloma": a new epithelioid granuloma of the skin.

PMID- 4345901
TI  - Retrobulbar granular cell myoblastoma.

PMID- 4345902
TI  - Results of early mobilization and discharge after myocardial infarction.
AB  - A total of 342 patients with acute myocardial infarction who were admitted to a
      coronary care unit are reviewed to assess the results of early mobilization and
      discharge. The mean duration of admission was 8.4 days and 89% of the survivors
      were discharged from hospital by the tenth day. The inpatient mortality was
      15.5%. An additional 6.7% died during the six weeks' follow-up period, giving a
      total mortality of 22.2%. Altogether, 7.6% of patients were readmitted. Venous
      thromboembolic phenomena occurred in 3.5% during the inpatient period. Of
      patients who were eligible 62% were back at work five months after their
      myocardial infarction. We think the results justify a short hospital admission
      period for acute myocardial infarction.

PMID- 4345903
TI  - Immunological studies in Ugandan patients with hepatocellular carcinoma.
AB  - Immunological studies were performed on Ugandan patients with hepatocellular
      carcinoma to test the hypothesis that the high rate of persistence of hepatitis
      associated antigen in these patients is the result of defects in host immune
      response. The responses to 1-chloro-2,4-dinitrobenzene sensitization and to a
      battery of recall skin test antigens were normal, as was the humoral antibody
      response to tularaemia antigen. Neither hypogammaglobulinaemia nor specific
      immunoglobulin deficiencies were found. Thus it appears unlikely that generalized
      defects in host immune responses can account for the high incidence of persistent
      hepatitis B virus infection found in Ugandan patients with hepatocellular
      carcinoma.

PMID- 4345905
TI  - Zollinger-Ellison syndrome revisited.

PMID- 4345904
TI  - Triglyceride storage disease: a disorder of lipolysis in adipose tissue in two
      patients.
AB  - An obese patient was studied whose adipose tissue showed a significant reduction
      in release of glycerol (P < 0.05) when stimulated by isoprenaline despite normal
      rises in tissue levels of cyclic-AMP. However, lipolysis was stimulated by a fast
      of 14 days as judged by weight loss and a rise in plasma fatty acids from 0.4 to
      1.2 mM. The defect in this patient may be familial since her obese daughter also
      showed diminished release of glycerol from adipose tissue on three occasions when
      stimulated by isoprenaline, despite normal rises in levels of cyclic-AMP.

PMID- 4345906
TI  - Where to die.

PMID- 4345907
TI  - Monkeypox.

PMID- 4345908
TI  - Four recurring themes.

PMID- 4345909
TI  - Ocular dyskinesia in cerebellar disease. Evidence for the similarity of
      opsoclonus, ocular dysmetria and flutter-like oscillations.

PMID- 4345910
TI  - Hereditary neuropathy with liability to pressure palsies. Electrophysiological
      and histopathological aspects.

PMID- 4345911
TI  - Purification and properties of rat liver nuclear protein kinases.

PMID- 4345912
TI  - Lipid composition and synthesis in the muscles of normal and dystrophic chickens.

PMID- 4345913
TI  - The amino acid sequence of cytochrome c-553 from the Chrysophycean alga
      Monochrysis lutheri.

PMID- 4345914
TI  - Purification of isoenzyme and coenzymes for kinetic study of horse liver alcohol
      dehydrogenase.

PMID- 4345915
TI  - Kinetic mechanism for the major isoenzyme of horse liver alcohol dehydrogenase.

PMID- 4345916
TI  - Adenylate cyclase and insulin action. Effect of insulin, nonsuppressible insulin
      like material, and diabetes on adenylate-cyclase activity in mouse liver.

PMID- 4345918
TI  - Secondary antibody-forming potential of aged mice, with special reference to the
      influence of adjuvant on priming.

PMID- 4345917
TI  - Bicuculline and thalamic inhibition.

PMID- 4345919
TI  - The activation of chloride transport by epinephrine and Db cyclic-AMP in the
      cornea of the rabbit.

PMID- 4345920
TI  - Ultraviolet-sensitive mutator strain of Escherichia coli K-12.
AB  - An ultraviolet (UV)-sensitive mutator gene, mutU, was identified in Escherichia
      coli K-12. The mutation mutU4 is very close to uvrD, between metE and ilv, on the
      E. coli chromosome. It was recessive as a mutator and as a UV-sensitive mutation.
      The frequency of reversion of trpA46 on an F episome was increased by mutU4 on
      the chromosome. The mutator gene did not increase mutation frequencies in
      virulent phages or in lytically grown phage lambda. The mutU4 mutation
      predominantly induced transitional base changes. Mutator strains were normal for
      recombination and host-cell reactivation of UV-irradiated phage T1. They were
      normally resistant to methyl methanesulfonate and were slightly more sensitive to
      gamma irradiation than Mut(+) strains. UV irradiation induced mutations in a
      mutU4 strain, and phage lambda was UV-inducible. Double mutants containing mutU4
      and recA, B, or C were extremely sensitive to UV irradiation; a mutU4 uvrA6
      double mutant was only slightly more sensitive than a uvrA6 strain. The mutU4
      uvrA6 and mutU4 recA, B, or C double mutants had mutation rates similar to that
      of a mutU4 strain. Two UV-sensitive mutators, mut-9 and mut-10, isolated by
      Liberfarb and Bryson in E. coli B/UV, were found to be co-transducible with ilv
      in the same general region as mutU4.

PMID- 4345921
TI  - Survival of Arthrobacter crystallopoietes during prolonged periods of extreme
      desiccation.
AB  - Cells of Arthrobacter crystallopoietes mixed in sand and air-dried have survived
      for up to 6 months after an initial period in which approximately half the cells
      lost their viability. Comparative survival curves have been obtained from
      inoculated sands maintained under CaSO(4) or P(2)O(5). Selections for more
      desiccation-resistant progeny capable of surviving the initial period were
      unsuccessful. Both the coccoid and rod-shaped forms are equally resistant to
      several months of desiccation. Desiccated spherical cells converted 0.0005% of
      their cell carbon to carbon dioxide per hr, which corresponds to a half-life for
      self-consumption of approximately 12 years.

PMID- 4345922
TI  - Specialized subregions of the bifunctional hisB gene of Salmonella typhimurium.
AB  - Forty-three hisB mutants of Salmonella typhimurium have been screened to
      determine the molecular size of the resulting histidinol phosphate phosphatase
      activity, one of the activities of a bifunctional enzyme produced by this gene
      which also controls imidazole glycerol phosphate dehydrase activity. Mutation in
      hisB can lead to the loss of both phosphatase and dehydrase activities, or only
      of dehydrase activity. Through the use of nonsense mutants lacking dehydrase
      activity, a distinct point of transition was detected near the middle of hisB at
      which a dramatic change occurs in the size of the phosphatase enzyme that is
      synthesized. A missense mutant with a lesion in this region has a high-molecular
      weight enzyme which is eluted in the void volume of a Sephadex G-200 column. The
      enzyme from nonsense mutants near the transition point have molecular weights
      near 40,000. Even though the buffer conditions are designed to favor the
      stabilization of the high-molecular-weight form, some mutants have both high- and
      low-molecular-weight forms. The polypeptide chain specified by the operator
      proximal part of hisB is sufficient to allow the expression of phosphatase
      activity. The synthesis of substantially less than the complete product of hisB
      resulted in association into a form similar to the native enzyme which was found
      in the void volume of a Sephadex G-200 column.

PMID- 4345924
TI  - Electron-microscope observations on the formation of the cytoplasmic lamellar
      inclusion bodies in murine pulmonary tumours induced in vitro.

PMID- 4345923
TI  - Acute renal failure followed by protracted, slowly resolving chronic uremia.

PMID- 4345925
TI  - Membrane depolarization, cyclic AMP and glycerol release by brown fat in vitro.

PMID- 4345926
TI  - Inhibition of post-ganglionic motor transmission in vas deferens by indirectly
      acting sympathomimetic drugs.
AB  - 1. Using field stimulation with short trains of pulses (< 10 per train), the post
      ganglionic motor transmission in the mammalian vas deferens has been further
      analysed pharmacologically.2. In preparations taken from guinea-pigs, rats and
      rabbits the effects of the indirectly sympathomimetic drugs, tyramine and
      cocaine, could be explained entirely on the basis of the actions of released,
      endogenous noradrenaline.3. Tyramine produced a contraction in vasa taken from
      normal rats but not from normal guinea-pigs. The tyramine contraction was due to
      release of endogenous noradrenaline because it was not seen in preparations taken
      from reserpinized rats and because it was abolished in normal vasa by
      phenoxybenzamine or phentolamine, thus denying the supposed inaccessibility, to
      alpha-blockers, of the motor alpha-adrenoceptors activated by endogenous
      noradrenaline.4. Phenoxybenzamine or phentolamine failed to block post-ganglionic
      motor transmission in rat and in guinea-pig vasa.5. Tyramine strongly inhibited
      motor transmission in vasa taken from normal but not from reserpinized guinea
      pigs.6. Tyramine produced inhibition of motor transmission in phenoxybenzamine
      treated preparations taken from normal but not from reserpinized rats.7. Cocaine
      inhibited motor transmission in guinea-pig and in rat vasa. This effect was not
      due to a local anaesthetic or to a smooth-muscle depressant action because it did
      not occur in preparations taken from reserpinized animals.8. The inhibitory
      effect of tyramine or cocaine was not abolished by beta-adrenoceptor blockade
      with propranolol.9. Whereas reserpinization abolished the tyramine- and cocaine
      inhibitions, it did not affect the inhibitory actions of noradrenaline or of
      PGE(2).10. Indomethacin and sodium meclofenamate, which suppress prostaglandin
      synthesis, did not affect the twitch-inhibiting actions of noradrenaline,
      tyramine or cocaine.11. These results provide further support for the conclusion
      that post-ganglionic motor transmission to the vas deferens is non-adrenergic in
      these species and assign to endogenously released noradrenaline an inhibitory
      role upon motor transmission.

PMID- 4345927
TI  - Transmitter release from insect excitatory motor nerve terminals.
AB  - 1. Intracellular and extracellular electrodes were used to study spontaneous and
      impulse-linked release of transmitter at locust retractor unguis nerve-muscle
      synapses.2. At most extracellular recording sites the amplitude distributions of
      the excitatory post-synaptic potentials (e.p.s.p.s) were apparently non-Poisson.
      However, interpretation of these amplitude distributions was complicated by the
      effect on the extracellular recordings of the complex structural organization of
      the retractor unguis nerve terminal with its spatially distinct transmitter
      release sites extending over distances of 15-30 mum.3. The spontaneous miniature
      excitatory post-synaptic potentials (min e.p.s.p.s) did not occur at random
      intervals, bursts of min e.p.s.p.s being frequently recorded. As a result the
      spontaneous release of transmitter rarely approximated a Poisson process.4. For a
      period of at least 390 msec following a conditioning nerve impulse a test
      e.p.s.p. was facilitated and the probability of spontaneous transmitter release
      was enhanced. A large primary phase of facilitation of impulse-linked and
      spontaneous release was invariably followed by one or more secondary phases of
      smaller magnitude.

PMID- 4345928
TI  - Historical vignette. Calomel and the American medical sects during the nineteenth
      century.

PMID- 4345929
TI  - Experience with radioisotope scanning of the pancreas.

PMID- 4345930
TI  - Properties of a temperature sensitive plasmid in Citrobacter freundii.

PMID- 4345931
TI  - [Australia antigen in blood transfusion].

PMID- 4345932
TI  - [Treatment of myasthenia].

PMID- 4345933
TI  - [Ornithine-carbamoyl-transferase and its clinical valve].

PMID- 4345934
TI  - Symptomatic hypoglycemia in adults: a protocol for clinical and laboratory
      evaluation.

PMID- 4345935
TI  - Plasmodial ultrastructure of the myxomycete Physarum polycephalum.

PMID- 4345936
TI  - Fine structural studies on digestion of bacterial species in the rumen ciliate,
      Entodinium caudatum.

PMID- 4345937
TI  - Morphology and behaviour of cultured aedes aegypti mosquito cells.

PMID- 4345938
TI  - [Diabetes mellitus and coffee].

PMID- 4345939
TI  - [Effect of caffeine containing and caffeine free coffee on human sleep].

PMID- 4345940
TI  - The fine structure of the human oocyte. I. Oval granulo-vesicular bodies.

PMID- 4345941
TI  - Immunocytological observations on the localization of ACTH in the hypophysis of
      the dog.

PMID- 4345942
TI  - Structural studies on the synapsis of the toad, Bufo arenarum, Hensel. I. Special
      forms of dendro-dendritic, dendro-somatic and axo-somatic contacts.

PMID- 4345944
TI  - Mononucleosis with heterophil antibodies and EB virus infection. Acquisition by
      an elderly patient in hospital.

PMID- 4345943
TI  - Serial lipid and lipoprotein responses to the American Heart Association fat
      controlled diet.

PMID- 4345945
TI  - Recurrent lacrimal gland tumor.

PMID- 4345946
TI  - Electron microscope study of the morphogenesis of a new canine herpesvirus in dog
      kidney cells.

PMID- 4345947
TI  - Induction of DNase activity in monkey cell cultures infected by simian virus 40.

PMID- 4345948
TI  - Effect of panosialin on myxoviruses.

PMID- 4345949
TI  - Some aspects of the morphogenesis of myxoma virus in vivo.

PMID- 4345950
TI  - Viral replication in mouse macrophages.

PMID- 4345951
TI  - Comparison of SV 40 RNA from infected cells and SV 40 cRNA made by RNA polymerase
      from Escherichia coli.

PMID- 4345952
TI  - Role of spleen in production of virus induced interferon in rabbits. Brief
      report.

PMID- 4345953
TI  - Oestrogen metabolism in cultured human breast tumours.
AB  - The interconversion of tritium labelled oestrone and oestradiol-17beta has been
      investigated in human breast tumours maintained in organ culture for 3 days.
      Benign tumours were significantly different from scirrhous carcinomata both in
      the concentration of radioactivity taken up by the tissue and in the ratios of
      oestradiol-17beta/oestrone achieved. The fact that malignant tumours were able to
      convert oestrone to oestradiol-17beta is of interest in view of the relatively
      high plasma levels of oestrone in post-menopausal women.

PMID- 4345954
TI  - [Benign, giant-cell synovioma. Clinical picture, histology and electron
      microscopy].

PMID- 4345955
TI  - Why women form their own professional organizations.

PMID- 4345956
TI  - M.D.? Mrs.?--PM&R.

PMID- 4345958
TI  - Rehabilitation in modern medicine.

PMID- 4345957
TI  - The incidence and curability of cancer of the uterine cervix in El Paso County
      1944-1967.

PMID- 4345959
TI  - Characteristics of fast feedback control of corticotrophin release by
      corticosteroids.

PMID- 4345960
TI  - A chemostat study of the effect of fixed nitrogen sources on nitrogen fixation,
      membranes and free amino acids in Azotobacter chroococcum.

PMID- 4345962
TI  - Chemodectoma of larynx.

PMID- 4345961
TI  - The polar lipids of some species of Nocardia.

PMID- 4345963
TI  - The ultrastructure of chemodectoma of the larynx.

PMID- 4345965
TI  - C-type particles in primary and transplanted lung tumors induced in BALB-c mice
      by hydrazine sulfate: electron microscopic and immunodiffusion studies.

PMID- 4345964
TI  - [Radioimmunoassay of alpha-fetoprotein in primary and secondary cancer of the
      liver].

PMID- 4345966
TI  - Chronic poliovirus infection of cocultivated monkey cells harboring the Mason
      Pfizer monkey virus.

PMID- 4345967
TI  - Cell-mediated tumor immunity measured in vitro and in vivo with soluble tumor
      specific antigens.

PMID- 4345968
TI  - Mammary gland tumors in substrains C57BL-M and C57BL-He mice.

PMID- 4345969
TI  - An anemia-inducing virus derived from tumors caused by murine sarcoma virus-
      Moloney.

PMID- 4345970
TI  - Carcinoembryonic antigen: synthesis by a continuous line of adenocarcinoma cells.

PMID- 4345971
TI  - Growth of Rous sarcomas in bursectomized chickens.

PMID- 4345972
TI  - Differential enhancement of R-type virus particles in polyoma-transformed BHK-21
      cells by dimethyl sulfoxide.

PMID- 4345973
TI  - Spontaneous disseminated squirrel fibroma.

PMID- 4345974
TI  - Siegler R:Proposed classification of the murine leukemia-sarcoma viruses.

PMID- 4345975
TI  - The mechanism of enhanced clearance of colloidal carbon from the blood of rabbits
      stimulated with a tubercle bacillary lipid.

PMID- 4345976
TI  - [Treatment of chronic myelogenous leukemia with oral bis (3-mesyloxypropyl) amine
      p-toluenesulfonate].

PMID- 4345977
TI  - Bovine respiratory syncytial virus. Studies on an outbreak in Japan, 1968-1969.

PMID- 4345978
TI  - Distribution of antibodies in dogs against adenosatellite viruses.

PMID- 4345979
TI  - Distribution of complement-requiring neutralizing antibody against herpes simplex
      virus in human population.

PMID- 4345980
TI  - Sphingolipids of the fungi Phycomycetes blakesleeanus and Fusarium lini.

PMID- 4345981
TI  - Effects of parathion on lipolysis in isolated rat adipose tissue cells.

PMID- 4345982
TI  - [Studies on thin-layer chromatographic analysis of digitalis glycosides].

PMID- 4345983
TI  - [Florimycin and its effect on ciliated epithelium].

PMID- 4345985
TI  - Elephantiasis and silicates.

PMID- 4345984
TI  - Benign and malignant mixed tumours of the lung.

PMID- 4345986
TI  - Ultrastructural changes in the rat liver following protracted treatment with
      pregnenolone-16 -carbonitrile and digitoxin.

PMID- 4345987
TI  - Nucleoside triphosphatase activity in induced mammary tumours in rats.

PMID- 4345989
TI  - A survey of the viruses of farm animals in Northern Ireland.

PMID- 4345988
TI  - Open tubular heterogeneous enzyme reactors: preparation and kinetic behavior.

PMID- 4345990
TI  - An abnormality of adrenaline, phentolamine stimulated lipolysis in adipose tissue
      from obese, maturity-onset diabetics.

PMID- 4345991
TI  - The mechanism of insulin secretion after oral glucose administration. 3.
      Investigations on the mechanism of a reflectoric insulin mobilization after oral
      stimulation.

PMID- 4345992
TI  - [Parapsychology and quackery].

PMID- 4345993
TI  - The concentration of lactic acid in rabbit lenses of various ages.

PMID- 4345994
TI  - Retinal fine structure after long term anaesthesia.

PMID- 4345995
TI  - [Complement fixation test for Mycoplasma pneumoniae in the serodiagnosis of
      respiratory tract diseases].

PMID- 4345996
TI  - 8-Azaguanine resistance in mammalian cells. I. Hypoxanthine-guanine
      phosphoribosyltransferase.
AB  - Chinese hamster cells were treated with ethyl methanesulfonate or N-methyl-N'
      nitro-N-nitrosoguanidine, and mutants resistant to 8-azaguanine were selected and
      characterized. Hypoxanthine-guanine phosphoribosyltransferase activity of sixteen
      mutants is extremely negative, making them suitable for reversion to HGPRTase(+).
      Ten of the extremely negative mutants revert at a frequency higher than 10(-7)
      suggesting their point mutational character. The remaining mutants have
      demonstrable HGPRTase activity and are not useful for reversion analysis. Five of
      these mutants have < 2% HGPRTase and are presumably also HGPRTase point mutants.
      The remaining 14 mutants utilize exogenous hypoxanthine for nucleic acid
      synthesis poorly, and possess 20-150% of wild-type HGPRTase activity in in vitro.
      Their mechanism of 8-azaguanine resistance is not yet defined.

PMID- 4345997
TI  - The effect of cyclic AMP on the production of single-strand breaks in DNA of x
      irradiated E. coli B-r.

PMID- 4345998
TI  - Ultrastructural examination of ageing and radiation-induced life-span shortening
      in adult Drosophila melanogaster.

PMID- 4345999
TI  - Comparative effects of electron and neutron irradiation on the release of enzymes
      from isolated rat-spleen lysosomes.

PMID- 4346000
TI  - Rifampicin, an antitrachoma antibiotic.

PMID- 4346001
TI  - The natural history and diagnosis of herpes cornea.

PMID- 4346002
TI  - Studies on the molecular biology of herpes simplex virus.

PMID- 4346003
TI  - The effect of the antibiotics distamycin A and congocidine on the replication of
      herpes simplex virus.

PMID- 4346004
TI  - Collagenolytic enzymes in corneal pathology.

PMID- 4346005
TI  - The interaction of serum and arterial lipoproteins with elastin of the arterial
      intima and its role in the lipid accumulation in atherosclerotic plaques.
AB  - Arterial elastin appears to be a proteinlipid complex with the lipid component
      being bound to elastin peptide groups. In atherosclerotic lesions the lipid
      content of elastin increases progressively with increasing severity of
      atherosclerosis. The increases in the lipid content of plaque elastin are mainly
      due to large increases in cholesterol with about 80% of the cholesterol being
      cholesterol ester. This deposition of cholesterol in elastin accounts for a
      substantial part of the total cholesterol accumulation in atherosclerotic lesions
      of all stages. The present in vitro study suggests that the mechanism involved in
      the deposition of lipids in arterial elastin may be an interaction of the elastin
      protein with serum or arterial low density or very low density lipoproteins (LDL
      and VLDL) resulting in a transfer of lipids, but not of lipoprotein protein to
      the elastin. No significant lipid transfer occurred from the high density
      lipoproteins or chylomicrons. The amount of lipid taken up by plaque elastin was
      strikingly higher than by normal elastin and consisted mainly of cholesterol with
      over 80% of the cholesterol being cholesterol ester. The precondition for the
      lipid accumulation in plaque elastin appeared to be an altered amino acid
      composition of the elastin protein consisting of an increase in polar amino acids
      and a reduction in cross-linking amino acids. Subsequent treatment of lipoprotein
      incubated arterial elastin with hot alkali and apolipoproteins did not reverse
      the binding of lipoprotein lipid to diseased elastin.

PMID- 4346006
TI  - Direct measurement of osteolysis in man.
AB  - Precise, direct measurement of bone calcium release (v(o-)) has been accomplished
      using a continuous tracer administration (CTA) technique. Dietary calcium (96.97%
      (40)Ca) is replaced by (40)Ca (99.991% (40)Ca) and blood levels of the naturally
      occuring isotope (48)Ca are monitored by neutron activation analysis as a
      function of time. (48)Ca abundance falls as this isotope is excreted and only
      partially replaced by release from bone. After a suitable period, an asymptotic
      abundance of (48)Ca in serum, E, is approached which is the fraction of the
      turnover rate of the rapidly exchangeable calcium pools coming from the skeleton
      (E = v(o-)/v(t)). E is determined with a standard error of 2%, providing a
      precise, sensitive index of v(o-). 13 studies in three normal men and one
      postmenopausal woman receiving maintenance estrogen show large intersubject
      variations in parameters of calcium metabolism using both CTA and pulse tracer
      administration (PTA) plus balance techniques. Induced hypercalcemia results in a
      prolonged decrease in v(o-). Glucocorticoid therapy initially and consistently
      induces a marked hypercalciuria while effects on most other parameters of calcium
      kinetics are variable. In two men E fell when testosterone was added to
      glucocorticoid treatment, consistent with the known antiosteolytic effect of
      androgens, despite the short period of study.

PMID- 4346007
TI  - Mechanism of the lower esophageal sphincter relaxation. Action of prostaglandin E
      1  and theophylline.
AB  - The intravenous injection of prostaglandin E(1) (PGE(1)) causes a dose-dependent
      relaxation of the lower esophageal sphincter (LES) in the intact, lightly
      anesthetized opossum. The action of PGE(1) is not inhibited by the drugs that
      produce muscarinic or nicotinic cholinergic antagonism or alpha and beta
      adrenergic antagonism in the doses that inhibited the action of respective
      agonists. Moreover, this action is not affected by exogenous gastrin
      pentapeptide. The action of PGE(1) on the LES is mimicked by isoproterenol,
      theophylline ethylenediamine, and dibutyryl cyclic AMP. Both theophylline, a
      phosphodiesterase inhibitor, and isoproterenol, an adenyl cyclase stimulator,
      added to the action of PGE(1). On the other hand, adenyl cyclase inhibitor
      nicotinic acid, as well as phosphodiesterase stimulator, imidazole inhibited its
      action. Further, both nicotinic acid and imidazole inhibited the degree of LES
      relaxation produced by esophageal distension. These studies suggest that
      intracellular cyclic AMP may act as the "second messenger" in the regulation of
      the lower esophageal sphincter relaxation.

PMID- 4346008
TI  - Activation of renal cortical adenylate cyclase by circulating immunoreactive
      parathyroid hormone fragments.
AB  - Three distinct immunoreactive species of parathyroid hormone (PTH) are present in
      human serum. One has an estimated mol wt of 9,500 and probably represents
      glandular hormone, the second 7,000-7,500 mol wt, and the third 4,500-5,000 mol
      wt. In order to assess the biological activity of these circulating forms of PTH,
      we determined their ability to activate renal cortical adenylate cyclase. The
      9,500 mol wt and 4,500-5,000 mol wt fractions produced four- to sixfold increases
      in cyclic 3',5'-AMP accumulation above control; the 7,000-7,500 mol wt fraction
      was inactive. None of the fragments had any effects on phosphodiesterase
      activity. Antiserum to bovine PTH did not block the activation of adenylate
      cyclase by either the gragments or bovine PTH. The data suggest that a large
      proportion of circulating immunoreactive human PTH is biologically active and
      that the biologically and immunologically active sites of the hormone are
      distinct.

PMID- 4346009
TI  - Studies on respiratory immunization with tetanus toxoid: the role of adjuvants.
AB  - Aerosol vaccination of mice with purified plain tetanus toxoid does not induce an
      immune response unless a suitable adjuvant is added.Aluminium phosphate is
      without effect by aerosol treatment. Killed cells of Klebsiella pneumoniae,
      although effective, are unsatisfactory owing to the long inhalation period
      needed.Killed Bordetella perussis cells were found to be an excellent adjuvant. A
      single aerosol treatment with a toxoid-B. pertussis mixture during a moderate
      exposure period evoked a considerable immune response. With repeated aerosol
      treatment of primed mice the addition of adjuvant is not required; booster
      treatment with plain toxoid is at least as effective.Extracts from B. pertussis
      cells exert as good an adjuvant effect as the whole-cell vaccine. The remaining
      cell-wall debris also appears to be an active adjuvant.In combination with
      constant doses of adjuvant (10(8)B. pertussis cells), the 50% protective doses
      (ED 50) of toxoid were determined by inhalation and by s.c. injection and were
      found to be 0.1875 and 0.0625 LFU respectively. This would imply that, as a
      result of the adjuvant action, the s.c. ED 50 is reduced by approximately a
      factor of 20; whereas the respiratory ED 50 is decreased by at least a factor of
      100.It is suggested that the much more pronounced adjuvant activity in aerosol
      immunization is associated with the induction of strong cell-mediated
      hypersensitivity in the respiratory tract.

PMID- 4346010
TI  - Serological studies in a student population prone to infection with human
      papilloma virus.
AB  - Four hundred and sixty-seven serum specimens from the female students at a
      residential college were examined for the presence of circulating antibody to
      human wart virus using the technique of counter-current
      immunoelectroosmophoresis. A significantly higher incidence of antibodies was
      found in students with a past history of plantar warts than in any other group.
      Antibody took several months to develop and was detectable in 20-30% of the
      students up to 9 years after infection. From a few cases of multiple infection,
      it was shown that reinfection could occur in spite of the presence of circulating
      antibodies probably of the IgG class. The sensitivity of the test was compared
      with two recognized techniques for detection of wart virus antibodies, namely gel
      diffusion and passive haemagglutination.

PMID- 4346011
TI  - Passive protection of mice against intracerebral infections with Bordetella
      pertussis.
AB  - The passive protection of mice against an intracerebral infection with Bordetella
      pertussis, by antiserum introduced directly into the brain with the infecting
      organisms, was compared with the protection afforded by intraperitoneal
      antiserum. The antibody effective by the intracerebral route is that which is
      adsorbed onto the infecting organisms, although it does not affect the viability
      of the organisms in vitro in the absence of complement.PASSIVE PROTECTION AGAINST
      ORGANISMS INTRODUCED INTRACEREBRALLY TAKES PLACE IN ONE OF TWO WAYS, DEPENDING ON
      THE SIZE OF THE CHALLENGE: (1) after 3-4 days' growth, the growth rate declines
      so that the number of organisms does not reach the figure lethal for the mouse;
      (2) the organisms do not appear to multiply, as their numbers decline from the
      moment of injection, so that the brain is sterile after 2 days.Many of the mice
      protected against a challenge of 50,000 organisms (ca. 100 LD 50) by
      intraperitoneal or intracerebral antiserum recover by the first mechanism. The
      second mechanism operates after a smaller challenge of 5000 organisms (ca. 10 LD
      50), irrespective of whether the antiserum is given intracerebrally with the
      challenge, or intraperitoneally within several hours of challenge. Too much
      antiserum given intracerebrally with a 50,000 challenge, but not with a 5000
      challenge, inhibits protection.In some mice, virulent antibody-treated organisms
      which have not been killed, grow very slowly over a long period, but are
      eventually eliminated from the brain.

PMID- 4346012
TI  - Routine administration of oral polio vaccine in a subtropical area. Factors
      possibly influencing sero-conversion rates.
AB  - Poliomyelitis is an important problem of public health in warm-climate countries.
      Studies of serological responses to vaccination in these countries have given
      conflicting results but in many investigations the rates have been considerably
      less than in countries with temperate climates. In this study three possible
      factors influencing sero-conversion were investigated - the season of the year
      when vaccine was given, the social status of the mother (as indicated by the
      number of years of schooling) and the presence of non-poliomyelitis viruses (NPV)
      in the gut when vaccine was given.Over 200 children about 2 months of age were
      included in the study. Each was given three doses of trivalent vaccine at 6-week
      intervals.The sero-conversion rates of the groups fed in winter were excellent
      but were slightly less good in summer. The differences were greatest in children
      in the lower socio-economic groups and in children excreting other
      enteroviruses.The conclusions are that, provided a potent vaccine is used, the
      factors which diminish the effectiveness of immunization in warm-climate
      countries can be overcome: (1) by giving three doses of trivalent vaccine; (2) by
      beginning vaccination at the earliest possible age (when enteroviruses are
      fewest); (3) by concentrating special attention on the lower socio-economic
      groups and if necessary by giving a reinforcing dose several months after the
      third dose has been given - preferably in the colder months.

PMID- 4346013
TI  - Filamentous particles in human alveolar cell carcinomas: electron microscopy
      studies of six cases (preliminary report).

PMID- 4346015
TI  - Myoepithelioma with a leukemoid reaction in BALB-c mice.

PMID- 4346014
TI  - Kaposi's sarcoma: a new model in the search for viruses associated with human
      malignancies.

PMID- 4346016
TI  - Isolation and properties of cells releasing C-type particles from BALB-c embryo
      cell cultures.

PMID- 4346017
TI  - Fate of chromatin of interphase nuclei subjected to "phosphasing" in virus-fused
      cells.

PMID- 4346018
TI  - Impaired inflammatory response in tumor-bearing guinea pigs.

PMID- 4346019
TI  - Virus-specific nucleic acids in simian virus 40-transformed hamster cell clones
      varying in oncogenic potential.

PMID- 4346020
TI  - Feline malignant mammary tumors. I. Morphology and biology: some comparisons with
      human and canine mammary carcinomas.

PMID- 4346021
TI  - Polygraphic sleep study in craniopagus twins (where is the sleep transmitter?).
AB  - By means of polygraphic recordings complete independence of the sequence of
      sleeping and waking and of the two sleep states (REM and NREM) could be
      demonstrated in twins extensively conjoined at the skulls. Functionally important
      connections in the circulation of the two babies were found during subsequent
      preoperative investigations. These observations are at variance with the
      hypothesis of an extraneuronal humoral sleep-inducing factor based on crossed
      circulation experiments in animals; moreover they raise a new question about the
      transportation of the sleepregulating biogenic amines.

PMID- 4346022
TI  - Interval analysis of repetitive denervation potentials of human skeletal muscle.
AB  - Interval analyses of denervation potentials (fibrillation-potentials and positive
      sharp waves) in human skeletal muscles were performed using a DEC PDP-12
      computer. Extremely small differences between consecutive intervals (usually less
      than 1%) and slow up and down drifts in the spontaneous discharge frequency were
      found to be characteristic of repetitive denervation potentials. These two
      findings are safe criteria for the clinical diagnosis of denervation and they may
      be superior to the more commonly used criteria based upon the shapes, amplitudes,
      and durations of the potentials. Physiological data from the literature as well
      as hypotheses relating to spontaneous activity are reviewed. Generator potentials
      across the muscle fibre membrane, lowered firing threshold, and constant-sized
      after-potentials are considered the basic factors relevant to spontaneous and
      rhythmical firing and to the slow drift observed in the firing frequency.

PMID- 4346023
TI  - Interaction between voluntary contraction and tonic stretch reflex transmission
      in normal and spastic patients.
AB  - Transmission characteristics of tonic stretch reflex (TSR) pathways in both
      normal and spastic patients have been measured during different levels of
      sustained voluntary contraction of the biceps brachii muscle. A cross-correlation
      technique of analysis was used to separate reflex responses from the total
      electromyographic activity. TSR transmission in normal subjects was observed to
      change with the level of voluntary contraction; sensitivity to stretch increased
      approximately three-fold as the subject stiffened the arm by simultaneously
      contracting flexor and extensor muscles. In contrast, TSR transmission did not
      alter during voluntary contraction in spastic patients. It is proposed that in
      spastic patients supraspinal modulation of reflex transmission is impaired
      because hypersensitive spinal reflexes short-circuit long loop pathways.

PMID- 4346024
TI  - Nerve potentials and afferent conduction velocities in the differential diagnosis
      of amyotrophy of the hand.
AB  - Nerve action potentials recorded over the elbow after stimulation of the wrist
      were studied in patients with hand amyotrophy of different origin. In amyotrophic
      lateral sclerosis the amplitude of nerve action potentials does not change
      significantly even with extreme muscle wasting and loss of motor units.Studies of
      multisegmental afferent conduction velocities may demonstrate a strictly
      localized lesion with normal values above the compression.

PMID- 4346025
TI  - Corneal reflex in hemisphere disease.
AB  - The contralateral corneal reflex may be absent in patients with a deep lesion of
      the parietal lobe. Frontal and temporal lobe lesions apparently do not interfere
      with this reflex.

PMID- 4346026
TI  - Subacute spongiform encephalopathy. Electron microscopic studies.
AB  - Electron microscopic changes in brain biopsies from two cases of subacute
      spongiform encephalopathy are described. Large vacuoles seen in astrocytic and
      neuronal processes were surrounded by one or more concentric membranes. Dense
      core vesicles were found in axonal endings and in nerve cell perikarya; these
      particles could represent catecholamine-containing vesicles.

PMID- 4346027
TI  - A method for the quantitative determination of urinary estriol conjugates in
      human pregnancy.

PMID- 4346028
TI  - Possible mechanisms of anesthesia.

PMID- 4346029
TI  - Alpha-fetoprotein as an aid for diagnosis of primary hepatoma.

PMID- 4346030
TI  - Requirement of proteins S5 and S9 from 30S subunits for the ribosome-dependent
      GTPase activity of elongation factor G.
AB  - During CsCl isopycnic centrifugation at 20 mM Mg(++), Escherichia coli 30S
      ribosomal subunits specifically lose proteins S1, S2, S3, S5, S9, S10, and S14.
      The resultant 30S core is unable to stimulate the GTPase activity of EF-G in the
      presence of 50S subunits. Activity could be restored to a small extent by adding
      back S2, S5, or S9. However, when S5 and S9 were added together, they
      cooperatively produced 30S particles 1.5 times more active than the original
      native 30S subunits. The small amount of activity restored by S2 was simply
      additive to that restored by S5 or S9. None of the other split proteins showed
      any restoring capability. Ability of the various protein-deficient 30S particles
      to couple with 50S subunits corresponded closely to their activity in the EF-G
      GTPase reaction. It is concluded that S5 and S9 together enable the 30S subunit
      to participate in the formation of a GTPase-active 30S-50S-EF-G complex.

PMID- 4346031
TI  - Malignant lymphomas of African children.
AB  - Clinical, pathologic, and epidemiologic observations of malignant tumors of
      children in sub-Sahara Africa suggest alternative theories of causation, and give
      insight into environmental influences that may play a large role in the etiology
      and form of malignant lymphatic tumors and cerebral neoplasms of infants.

PMID- 4346032
TI  - Prevention of simian virus 40 tumors by hamster fetal tissue: influence of parity
      status of donor females on immunogenicity of fetal tissue and on immune cell
      cytotoxicity.
AB  - Fetal tissue from primiparous hamsters prevented simian virus 40 (SV40)
      tumorigenesis in male hamsters, whereas fetal tissue from multiparous hamsters
      did not. The parity status of normal (uninoculated) hamsters also influenced the
      cytotoxicity of their lymphoid cells against tumor cells. Lymph node cells from
      nonpregnant primiparous and multiparous animals were cytotoxic in
      microcytotoxicity tests against SV40, polyoma, and adenovirus 7 tumor cells, but
      were not active against control BHK cells. Lymph node cells from virgin female
      donors were inactive. Peritoneal exudate cells from these donors reacted in
      similar fashion against SV40 tumor cells in vitro and in adoptive transfer tests
      in vivo. However, the cytotoxicity of peritoneal exudate cells from multiparous
      hamsters was greatly reduced during pregnancy, a time when noncytotoxic humoral
      antibody reactive with surface antigen of SV40 tumor cells is present. This
      humoral antibody is not detected during first pregnancy, and peritoneal exudate
      cells obtained from pregnant primiparous hamsters demonstrated a high degree of
      cytotoxicity.

PMID- 4346033
TI  - Release of infectious Epstein-Barr virus by transformed marmoset leukocytes.
AB  - Marmoset blood leukocytes transformed in vitro by Epstein-Barr virus regularly
      release extracellular infectious Epstein-Barr virus with high titers of
      transforming activity. By comparison, human umbilical cord leukocytes and adult
      human leukocytes transformed by Epstein-Barr virus release either no
      extracellular infectious virus or small amounts, irregularly.

PMID- 4346034
TI  - Double-stranded RNA as an inhibitor of protein synthesis and as a substrate for a
      nuclease in extracts of Krebs II ascites cells.
AB  - Concentrations of double-stranded RNA above about 0.1 mug/ml inhibit translation
      of encephalo-myocarditis viral RNA and mouse globin messenger RNA in extracts of
      Krebs II ascites cells. Protein synthesis initially proceeds at the control rate,
      then abruptly shuts off in a manner similar to that observed in reticulocyte
      lysates [Hunt, T. & Ehrenfeld, E. (1971) Nature New Biol. 230, 91-94].
      Substantially higher concentrations of double-stranded RNA are required to give
      this effect in ascites extracts. Subcellular fractions of Krebs II ascites cells
      contain a nucleolytic activity capable of digesting several natural and synthetic
      double-stranded RNAs. This nuclease is most active under conditions of protein
      synthesis, and part of the activity remains associated with ribosomes upon
      sedimentation. It is probably because of digestion of double-stranded RNA by this
      nuclease that higher concentrations of double-stranded RNA are required for
      inhibition of protein synthesis in Krebs cell extracts than in reticulocyte
      lysates.

PMID- 4346035
TI  - Mutagenic DNA polymerase in human leukemic cells.
AB  - Evidence is presented that DNA polymerases from human leukemic cells are
      mutagenic. Nucleic acid-free extracts of acute lymphoblastic leukemic cells
      polymerized about 10-times more dCTP using poly(dA-dT).poly(dA-dT) as a template
      than did extracts from normal lymphocytes. Mutagenic DNA polymerases could
      perhaps play an important role in tumor progression.

PMID- 4346036
TI  - Structural characteristics of some murine RNA tumor viruses studied by
      lactoperoxidase iodination.
AB  - Iodination by the noninvasive enzymatic lactoperoxidase technique has been used
      to study the enzyme-accessible and enzyme-inaccessible proteins of three oncorna
      viruses (radiation leukemia virus, Moloney leukemia virus, and mouse mammary
      tumor virus). The number and relative molecular weight of proteins associated
      with virion preparations purified on sucrose gradients were characterized by
      scans of Coomassie blue-stained bands after dodecyl sulfate-polyacrylamide gel
      electrophoresis. Gel scans from the leukemia viruses are similar, each showing
      six distinct major protein bands on stained gels. The mammary tumor virus
      proteins by this analysis are not similar to those of the leukemia viruses.
      Enzymatic iodination of intact virion preparations led to the solitary labeling
      of one of the major proteins of each virus-the 80,000-dalton protein of the
      leukemia viruses and the 52,500-dalton protein of the mammary tumor virus. These
      are tentatively positioned as surface (enzyme-accessible) moieties in the
      virions. Disruption of each virus with a nonionic nonionic detergent before
      enzymatic iodination led to the labeling of the remaining stainable bands. The
      four lower molecular weight bands of the leukemia viruses are tentatively
      positioned as internal (enzyme-inaccessible) components.

PMID- 4346037
TI  - Malignant transformation of BHK21 clone 13 cells in vitro by nitrosamines--a
      conditional state.
AB  - All the BHK(21) Clone 13 cells transformed by dimethylnitrosamine or
      nitrosomethylurea, and a single "spontaneously" transformed clone obtained in our
      laboratory, exhibit a conditional state of the transformed phenotype. Upon growth
      at 38.5 degrees , they have a transformed phenotype (clonal morphology and the
      ability to plate in soft agar); when grown at 32 degrees , their phenotype is
      normal. The conditional state of these cells, however, does not extend to their
      growth characteristics; their plating efficiency at the two temperatures in
      liquid medium is similar. Conversion from the normal to the transformed phenotype
      and the reverse is possible by temperature shifts. A working hypothesis is
      proposed suggesting that this phenomenon may be caused by a temperature-sensitive
      mutation of a cellular gene whose product is responsible for maintaining the
      normal phenotype. The high temperature would then affect either the synthesis or
      the function of the protein carrying the temperature-sensitive alteration and, as
      a consequence, the transformed phenotype would be expressed.

PMID- 4346038
TI  - Production of mucopolysaccharides by normal and transformed cells.
AB  - The rate of hyaluronic acid and sulfated mucopolysaccharide production was
      measured for hamster embryo fibroblasts and for general oncogenic lines derived
      by virus transformation. A striking increase in both the rate of hyaluronic acid
      synthesis and the amount of cell-associated polymer was observed after
      transformation by herpes simplex type-2 or SV40 virus. Although no corresponding
      change was observed for the sulfated polysaccharides, the proportion of heparan
      sulfate increased significantly after transformation.

PMID- 4346039
TI  - RNA related to that of a murine leukemia virus in Burkitt's tumors and
      nasopharyngeal carcinomas.
AB  - RNA homologous to that of the Rauscher leukemia virus has been detected in
      Burkitt's lymphomas and nasopharyngeal carcinomas. Earlier excellent experimental
      evidence has linked these two human tumors with the Epstein-Barr virus, a DNA
      containing agent.

PMID- 4346040
TI  - Electron spin resonance studies of spin-labeled mammalian cells by detection of
      surface-membrane signals.
AB  - Lipid-soluble spin labels were incorporated into human lymphocytes and mouse L
      cells and the resulting electron spin resonance spectra were compared with
      spectra obtained from similarly labeled human erythrocytes. Spin labels were
      found in all subcellular fractions of the nucleated cells that contained
      membranes. Spinlabeled cells remained viable and capable of replicating in vitro.
      Electron spin resonance signals from spin-labeled nucleated cells underwent a
      time- and temperature-dependent decay that was reversed by bathing the cells in
      K(3)Fe(CN)(6). The demonstration of a relative cell impermeability to
      ferricyanide, as measured by both colorimetric and radioisotopic label methods,
      indicated that only spin-labeled molecules in the surface membrane were
      reactivated when ferricyanide was added to spin-labeled cells after the electron
      spin resonance signal had decayed.

PMID- 4346041
TI  - Induction of cytolysis of cultured lymphoma cells by adenosine 3':5'-cyclic
      monophosphate and the isolation of resistant variants.
AB  - Cultured mouse lymphosarcoma cells are killed on exposure to 0.1 mM N(6),O(2')
      dibutyryl-adenosine 3':5'-cyclic monophosphate. A population of cells resistant
      to the killing effect of dibutyryl cyclic AMP at concentrations as high as 1 mM
      was selected. The growth characteristics of the resistant cells were similar to
      those of the sensitive parental line. However, the resistant cells contain less
      cytoplasmic cyclic AMP-binding proteins and decreased cyclic AMP-stimulated
      protein kinase activity. It is proposed that transition from sensitivity to
      resistance to dibutyryl cyclic AMP in lymphoma cells is connected with a
      modification of the cyclic AMP-binding protein, which appears to be the
      regulatory subunit of the cyclic AMP-activated protein kinase.

PMID- 4346042
TI  - Pharmacology of the brain: the hippocampus, learning and seizures.

PMID- 4346043
TI  - [2 thecal tumors of the ovary].

PMID- 4346044
TI  - [Cytomegalovirus infection with septic fever, pnemonia and hepatitis in renal
      transplantation].

PMID- 4346045
TI  - Adenosine 3',5'-monophosphate: electrophysiological evidence for a role in
      synaptic transmission.
AB  - Synaptic potentials and changes in resting membrane potentials of superior
      cervical ganglia of the rabbit were measured in the presence of adenosine 3',5'
      monophosphate and agents that affect its metabolism. Adenosine 3',5'
      monophosphate and its mono- and dibutyryl derivatives caused a hyperpolarization
      of the postganglionic neurons. Theophylline potentiated the slow inhibitory
      postsynaptic potential that follows synaptic transmission, as well as the
      hyperpolarization of postganglionic neurons caused by exogenous dopamine.
      Conversely, prostaglandin E(1) inhibited both the slow inhibitory postsynaptic
      potential and the dopamine-induced hyperpolarization. We hypothesize that the
      slow inhibitory postsynaptic potential as well as the dopamine-induced
      hyperpolarization result from increased amounts of adenosine 3'5'-monophosphate
      in the postganglionic neurons. The dibutyryl derivative of guanosine 3'5'
      monophosphate caused a depolarization of the postganglionic neurons, which is
      consistent with the possibility that guanosine 3'5'-monophosphate mediates
      synaptic transmission at muscarinic cholinergic synapses.

PMID- 4346046
TI  - Anaesthesia of fish.

PMID- 4346047
TI  - [Evolutionary aspects of synaptic transmission].

PMID- 4346049
TI  - [Polyphosphoinositides in subcellular fractions of rat brain].

PMID- 4346048
TI  - [Electrophysiology studies on natural sleep and wakefulness in turtles and hens].

PMID- 4346050
TI  - Psammoma bodies found in cervico-vaginal smears.

PMID- 4346051
TI  - Amounts of gonadotrophins required for normal follicular growth in
      hypophysectomized adult rats.

PMID- 4346052
TI  - Effect of progesterone on the time of ovulation in immature rats pretreated with
      pregnant mare's serum gonadotrophin (PMSG).

PMID- 4346053
TI  - C 21  steroid metabolism and conjugation in the human premature neonate. 2.
      Tissue metabolism and conjugation of exogenous cortisol, 11-deoxycortisol,
      corticosterone and pregnenolone in the presence and absence of ACTH in vitro.

PMID- 4346054
TI  - Imitation of the adreno-cortical response to surgery by intravenous infusion of
      synthetic human ACTH.

PMID- 4346055
TI  - [Familial and sporadic hypophosphatemic vitamin D resistant rickets].

PMID- 4346056
TI  - Reduction malformations and chromosome anomalies.

PMID- 4346057
TI  - Undifferentiated lymphoma, non-Burkitt's type. Meningeal and bone marrow
      involvement in children.

PMID- 4346059
TI  - Development of hip dysplasia in dogs.

PMID- 4346058
TI  - Estrogen treatment of tall girls.

PMID- 4346060
TI  - Mechanisms of platelet function as revealed by the retention of platelets in
      glass bead columns.

PMID- 4346061
TI  - Adhesion of platelets to subendothelium.

PMID- 4346062
TI  - The control of platelet responsiveness by agents that influence cyclic AMP
      metabolism.

PMID- 4346063
TI  - Cyclic 3',5'-adenosine monophosphate in human blood platelets. IV. Regulatory
      role of cyclic amp in platelet function.

PMID- 4346064
TI  - [Estrogen-producing tumors of the ovary and their relation to the endometrial
      carcinoma].

PMID- 4346065
TI  - Purification and properties of cytochrome c (550: Hemispora stellata).

PMID- 4346067
TI  - Rapid single-step kinetic colorimetric assay for lactate dehydrogenase in serum.

PMID- 4346066
TI  - [Metabolic products of microorganisms. 114. Thymidine diphospho-D-glucose
      oxidoreductase from Streptomyces rimosus].

PMID- 4346068
TI  - Polyacrylamide-gel disc-electrophoresis as a screening procedure for serum
      lipoprotein abnormalities.

PMID- 4346069
TI  - Polyacrylamide-gel block-electrophoresis of plasma lipoproteins.

PMID- 4346072
TI  - Additional observations on hydrochlorothiazide interference with measurement of
      total urinary placental estrogens.

PMID- 4346070
TI  - Automated kinetic spectrophotometric assays of enzyme activities of human
      cerebrospinal fluid: methods and reference values.

PMID- 4346071
TI  - Identification of lithocholic acid and measurement of other bile acids in serum
      of healthy humans.

PMID- 4346073
TI  - Enzyme determinations: criticisms of some recent reports.

PMID- 4346074
TI  - The lipid composition of the larval nervous system of Musca domestica. A
      comparison between insects susceptible and resistant to cyclodiene insecticides.

PMID- 4346075
TI  - [Frequency of B-particle-like structures in benign and malignant human breast
      tissue].

PMID- 4346076
TI  - Inhibition in vitro of cyclic 3',5' nucleotide phosphodiesterase activity by
      drugs.

PMID- 4346077
TI  - Experimental ocular studies with polyinosinic acid: polycytidylic acid.

PMID- 4346078
TI  - [Potentiating effect of strychnine on inhibitory axo-dendritic synaptic
      transmission in crayfish].

PMID- 4346079
TI  - [Homeostatic reactions of the kidney to hypertensive stimulation with stabilized
      arterial pressure].

PMID- 4346080
TI  - Subcellular localization of avian leucosis group-specific complement-fixing
      antigens in mouse ascites sarcoma cells (SR-C3H-He cells) induced by Schmidt
      Ruppin strain of Rous sarcoma virus.

PMID- 4346081
TI  - Mitochondrial oxidation of 3,3'-diaminobenzidine and related compounds, and their
      possible relation to carcinogenesis.

PMID- 4346082
TI  - Mechanism of antitumor action of dimethanesulfonylthiopentane.

PMID- 4346083
TI  - Transplacental carcinogenesis by urethan in mice: teratogenesis and
      carcinogenesis in relation to organogenesis.

PMID- 4346084
TI  - Immunohistological studies on mucosal glycoprotein in rectal carcinoma.

PMID- 4346085
TI  - Deviations in isozyme patterns of acid phosphatase and esterase, and in
      ultrastructures of Yoshida ascites hepatomas from rat hepatocytes.

PMID- 4346086
TI  - Hepatocarcinogenicity of polychlorinated biphenyls in mice.

PMID- 4346088
TI  - Effects of crystalline environment on pyrimidine free-radical formation: barbital
      crystal polymorphs and sodium barbital.

PMID- 4346087
TI  - [Development of the subcommissural organ of the rat. Morphological and
      histochemical studies].

PMID- 4346089
TI  - Aquaculture and associated diseases of fish of public health importance.

PMID- 4346090
TI  - Calcium-mediated effects of calcitonin on cyclic AMP formation and lymphoblast
      proliferation in thymocyte populations exposed to prostaglandin E 1 .

PMID- 4346091
TI  - Ammonia effects in cultures of normal and transformed 3T3 cells.

PMID- 4346092
TI  - Biochemical characteristics of normal and virally transformed mouse cell lines.

PMID- 4346094
TI  - Induction of reagin synthesis in the rat with associated and dissociated
      hemocyanin: effect of antilymphocyte serum.

PMID- 4346093
TI  - Acute herpetic gingivostomatitis in children.

PMID- 4346095
TI  - Proportion of T and B lymphocytes in lesions of Marek's disease: theoretical
      implications for pathogenesis.

PMID- 4346096
TI  - Infection of thymus cells in vivo and in vitro with a guinea pig herpes-like
      virus and the effect of antibody on virus replication in organ culture.

PMID- 4346097
TI  - In vitro assay of cellular immunity to tumor-specific antigen(s) of virus-induced
      tumors by macrophage migration inhibition.

PMID- 4346098
TI  - Preliminary x-ray studies of a cytochrome c from Micrococcus dentrificans.

PMID- 4346099
TI  - Circularity and cross-linking in preparations of replicative form of
      encephalomyocarditis virus RNA.

PMID- 4346100
TI  - Ultrastructural changes in Osmunda regalis Prothalli induced by X-irradiation.

PMID- 4346102
TI  - Crystalline inclusion bodies in the epididymis of the nine-banded armadillo.

PMID- 4346101
TI  - Cytokinesis in the stratum intermedium of the rat molar enamel organ.

PMID- 4346103
TI  - Electron microscopy of artichoke mottled crinkle virus in leaves of Chenopodium
      quinoa Willd.

PMID- 4346104
TI  - Contribution of polysynaptic pathways to the tonic vibration reflex.

PMID- 4346105
TI  - The positive after-potential following the orthodromic and antidromic propagated
      impulses in the frog muscle spindle.

PMID- 4346106
TI  - [Carcinoid tumors of bronchial localization (apropos of 4 cases)].

PMID- 4346107
TI  - Case records of the Massachusetts General Hospital. Weekly clinicopathological
      exercises. Case 8-1973.

PMID- 4346108
TI  - Ski-boot neuropathy.

PMID- 4346109
TI  - West Germany's geriatric patients: community care and after-care.

PMID- 4346110
TI  - Actions of adrenal, hypophysial and renal hormones on the renal excretion of
      water and electrolytes.

PMID- 4346111
TI  - [Orthostatic changes of plasma renin levels, circulatory mechanics and kidney
      function as well as of plasma catecholamines in normal individuals and patients
      with essential hypertension].

PMID- 4346112
TI  - [Interrelations of blood vessel sensitivity and electrolyte content of isolated
      arterial strip preparations as influenced by furosemide].

PMID- 4346113
TI  - [Aggravation of carbohydrate tolerance through vasopressin and angiotensin].

PMID- 4346114
TI  - [Influence of theophylline and dibutyryl-3'5-AMP on lipolysis and glucose
      metabolism in isolated adipose cells of rats].

PMID- 4346116
TI  - [Behavior of lipoproteins in diabetic coma].

PMID- 4346115
TI  - [Abnormal   1 -lipoprotein with reduced lipid-binding ability in a patient with
      generalized lymph node swellings, hepatosplenomegaly and hypocholesteremia].

PMID- 4346117
TI  - [Multiphasic course of induced lipolysis in isolated human adipose tissue
      sections].

PMID- 4346118
TI  - Effect of colchicine on the fine structure of the neuromuscular junction.

PMID- 4346119
TI  - Fine structure of the neural sheath, glia and neurons in the brain of the
      housefly, Musca domestica.

PMID- 4346120
TI  - Nervous system of the snail Helix aspersa. 3. Electron microscopic study of
      neurosecretory nerves and endings in the ganglionic sheath.

PMID- 4346121
TI  - [Comparative studies on the integument of hetero- and Eutardigrada].

PMID- 4346122
TI  - Studies of the fine structure of ovarian interstitial tissue. 7. The postnatal
      evolution of the thecal gland in the domestic fowl.

PMID- 4346123
TI  - Neuro-epithelial bodies in the respiratory mucosa of various mammals. A light
      optical, histochemical and ultrastructural investigation.

PMID- 4346124
TI  - Intrinsic autoregulatory control of heart rate and its applied and clinical
      implications.

PMID- 4346125
TI  - Histochemical studies on the morphology of the Golgi apparatus and on the
      distribution of hexokinase and some enzymes concerning vitamin C synthesis in the
      substantia nigra of the rabbit.

PMID- 4346126
TI  - The dynamics of histochemical changes in the epithelium of the small intestine of
      mice after experimental intraperitoneal intoxication with benzene.

PMID- 4346128
TI  - The avian intestinal flora with particular reference to the possible ecological
      significance of the cecal anaerobic bacteria.

PMID- 4346130
TI  - The etiology of respiratory tract infections in a tropical country.

PMID- 4346131
TI  - Home hemodialysis.

PMID- 4346132
TI  - Chlorpropamide in diabetes insipidus.

PMID- 4346133
TI  - The isolation and chemical composition of premelanosomes and melanosomes: human
      and mouse melanomas.

PMID- 4346134
TI  - Abnormal tryptophan metabolism in patients with scurvy-type skin.

PMID- 4346135
TI  - The group estimation of urinary 11-oxy-17-hydroxy-corticosteroids using gas
      liquid chromatography.

PMID- 4346136
TI  - Atachment of normal and transformed hamster kidney cells to substrata varying in
      chemical composition.

PMID- 4346137
TI  - Insulin from individual isolated mouse islets of Langerhans.

PMID- 4346138
TI  - [Effect of cyclic GMP and cyclic AMP on mouse thyroid function in vivo].

PMID- 4346139
TI  - [Corticostimulating activity of rat fetus hypophysis after maternal adrenalectomy
      and metopirone injections during gestation].

PMID- 4346140
TI  - [Influence of certain cyclic AMP metabolic effectors on the action of
      acetaldehyde, ethanol and acetate on lipolysis in vitro].

PMID- 4346141
TI  - [Attempted inoculation of fish rhabdoviruses into Drosophila melanogaster].

PMID- 4346142
TI  - [Ribonucleotide reductase from a mammalian rat tumor (Zajdela's hepatoma):
      stereospecificity of the reduction].

PMID- 4346143
TI  - [Demonstration, by means of allogenic antigens, of an antitumoral immunity with
      cellular mediation in humans].

PMID- 4346144
TI  - Effects of angiotensin I and antiotensin II on canine hepatic vascular
      resistance.

PMID- 4346145
TI  - Trypanosoma gambiense: cytopathologic changes in guinea pig hepatocytes.

PMID- 4346146
TI  - Enzymes of coccidia: purification and properties of L-lactate dehydrogenase from
      Eimeria stiedae.

PMID- 4346147
TI  - [Metabolic effects of arginine derivatives. 3. Insulin-like activity of L
      arginine-N,N-dialkylamides in vitro].

PMID- 4346148
TI  - [Biosynthesis of cytochrome c, II. Subcellular distribution of injected
      radioactive iron ( 59 Fe 2+ ) in various developmental stages of the honeybee].

PMID- 4346149
TI  - [Influence of testosterone on the phospholipids in seminal vesicles of immature
      rats].

PMID- 4346150
TI  - Comparative studies of lipid content and lipid metabolism of normal and
      transformed mouse cells.

PMID- 4346151
TI  - Kinetics of incorporation of ( 32 P)phosphate into phospholipids of a SV 40
      transformed mouse cell during logarithmic growth.

PMID- 4346152
TI  - Glycolipids of mouse fibroblasts and virus transformed mouse cell lines.

PMID- 4346153
TI  - Steroidglucuronyltransferases. 3. Oestradiol-17  3-glucuronyltransferase of the
      mitochondria of pig intestine.

PMID- 4346154
TI  - Steroidglucuronyltransferases. IV. Localization of the oestradiol-17 
      glucuronyltransferase in the outer membrane of the mitochondria of pig intestine.

PMID- 4346155
TI  - Comparison of the biological, biophysical and antigenic properties of four
      strains of infectious bovine rhinotracheitis herpesvirus.

PMID- 4346156
TI  - Pathogenesis of meningo-encephalitis produced in calves by infectious bovine
      rhinotracheitis herpesvirus.

PMID- 4346157
TI  - Pathogenicity of Talfan and Konratice strains of Teschen virus in gnotobiotic
      pigs.

PMID- 4346158
TI  - Infection of some species of African wild life with foot-and-mouth disease virus.

PMID- 4346159
TI  - The Merkel cell.

PMID- 4346160
TI  - A preliminary crystallographic investigation of rice cytochrome c.

PMID- 4346162
TI  - [Effect of hypoxia and vasoactive drugs on regional myocardial blood flow].

PMID- 4346161
TI  - [Electron microscopy of formalin-fixed biopsy and autopsy materials].

PMID- 4346163
TI  - Effects of oral contraceptives on the renin-angiotensin system and on blood
      pressure of normal young women.

PMID- 4346164
TI  - Epidemiology of acute lower respiratory disease in children.

PMID- 4346165
TI  - Acute promyelocytic leukemia in pregnancy.

PMID- 4346166
TI  - Diagnosis and treatment of hirsutism in women.

PMID- 4346167
TI  - EEG delta activity during human sleep as a damped ultradian rhythm.

PMID- 4346168
TI  - Haematemesis caused by oesophageal varices.

PMID- 4346169
TI  - Serum lipoprotein patterns in Bantu and Indian patients with nephrotic syndrome.

PMID- 4346170
TI  - Cyclic adenosine monophosphate and hypertension in rats.
AB  - Aortas from spontaneously hypertensive and stress hypertensive rats contained
      significantly lower intracellular concentrations of cyclic adenosine
      monophosphate than did their respective controls. Adenylate cyclase activity was
      normal but was less responsive to stimulation, while phosphodiesterase activity
      (especially the low Michaelis-Menten constant form) was significantly elevated.
      Human aortas contained two forms of phosphodiesterase that were similar to those
      in rat aortas.

PMID- 4346171
TI  - Virologic studies of generalized herpes zoster.

PMID- 4346172
TI  - [Radioimmunological determination of growth hormone in patients with acromegaly
      before and following treatment].

PMID- 4346173
TI  - [Clinical and experimental studies on the possibility to stimulate of ACTH
      secretion following administration of pethidine and chlorpromazine].

PMID- 4346174
TI  - [Case report on a female patient with 17- -hydroxylase deficiency].

PMID- 4346175
TI  - [Influence of cytostatic therapy on the immunologic reactivity of patients with
      chronic polyarthritis].

PMID- 4346176
TI  - [Studies on the behavior of microsomal enzymes in the rat liver following
      galactosamine administration].

PMID- 4346177
TI  - [Mediators in shock processes: pathogenetic and therapeutic problems].

PMID- 4346179
TI  - [Studies on changes of low-density lipoproteins (LDL) in liver diseases].

PMID- 4346178
TI  - [Development of connective tissue proliferation in the myocardium following the
      effect of various pathogenic stimuli].

PMID- 4346180
TI  - [Studies on the effect of temperature and pH change on the in-vitro incorporation
      of nucleic acid precursors in malignant tumors and normal tissues].

PMID- 4346181
TI  - [Studies on antibodies against the Epstein-Barr (EB) and cytomegalovirus (CM) in
      hemoblastoses and malignant tumors].

PMID- 4346182
TI  - [Intestinal hydrolysis of inosite phosphoric acid and absorption of phytin
      phosphorus in the swine. 2. Hydrolysis of inosite phosphoric acid in the
      intestinal tract of the swine].

PMID- 4346183
TI  - Monitoring of neuromuscular transmission in anesthetized man by a bulb-transducer
      assembly.

PMID- 4346184
TI  - [Primary malignant tumors of the gallbladder].

PMID- 4346185
TI  - A psychophysiological study of nightmares and night terrors. The suppression of
      stage 4 night terrors with diazepam.

PMID- 4346186
TI  - Monkeypox virus (MPV). I. Propagation, purification, and further
      characterization.

PMID- 4346187
TI  - Determination of plasma renin activity by radioimmunoassay of angiotensin I.

PMID- 4346188
TI  - Increase of plasma renin-substrate concentration after infusion of angiotensin in
      the rat.

PMID- 4346189
TI  - Evidence for free radical involvement in the hydroxylation of proline: inhibition
      by nitro blue tetrazolium.

PMID- 4346190
TI  - [The differential diagnosis of benign, solitary defects in the calvarium].

PMID- 4346191
TI  - [Evaluation of the venous phase of the vertebral angiogram].

PMID- 4346192
TI  - [Tomography in the Stenvers projection].

PMID- 4346193
TI  - [Mucocoeles of the paranasal sinuses--a problem in radiological diagnosis?].

PMID- 4346194
TI  - [Radiological proof to the traumatic origin of a spondylolysis].

PMID- 4346195
TI  - [A paired odontoid process--a rare malformation of the cranio-cervical
      transitional zone].

PMID- 4346196
TI  - [Fractures of the carpal bones].

PMID- 4346197
TI  - [Sources of error in the radiological evaluation of the operative results of
      medial femoral neck fractures].

PMID- 4346198
TI  - [Measurements of surface dose from exposures with special mammography apparatus].

PMID- 4346199
TI  - [Gonadal and lens doses to the patient and examiner during angiography of the
      lower half of the body, using a metaphosphate glass dosimeter (renal angiography,
      arteriography of the pelvis and extremities)].

PMID- 4346200
TI  - [Inadequate demonstration of the calyces. A disadvantage of infusion urography.
      Statistical analysis of 1,387 urograms].

PMID- 4346201
TI  - [The uricosuric effect of bilopaque (sodium tyropanoate). A contribution to the
      problem of nephro-toxicity of oral biliary contrast media].

PMID- 4346202
TI  - [Tumour scanning using  67 Ga citrate].

PMID- 4346203
TI  - [The value of  113m In-EDTA in modern brain tumour diagnosis].

PMID- 4346204
TI  - [Brain scans with  67 gallium].

PMID- 4346205
TI  - [Perfusion scanning of the pancreas with adrenalin].

PMID- 4346206
TI  - [Computer assistance for the evaluation of scans. A programme for renal
      scanning].

PMID- 4346207
TI  - Computer evaluation to the x-ray densitometry method for the diagnosis of
      calcipenic osteopathy.

PMID- 4346209
TI  - [Remarks on the paper of K. Sartor. "Symmetrical calcification of the arcus
      ileopectinei." Fortschr. Rontgenstr. 116,1:120].

PMID- 4346208
TI  - [Remarks on the paper of M. Schmidt: "Radiographic differentiation of psoriasis
      spondylarthritis from spondylarthritis ankylopoietica in psoriasis." Fortschr
      Rontgenstr.116(1972)486].

PMID- 4346210
TI  - [A rare hot metastasis in the brain scan].

PMID- 4346211
TI  - [Cortical osteoma of the frontal bone].

PMID- 4346212
TI  - [Petrous bone metastasis in breast carcinoma. Report on 2 observations].

PMID- 4346213
TI  - [Traumatic myositis ossificans with pseudarthrotic connections].

PMID- 4346214
TI  - [Chronic caisson osteoarthropathy in the glenoid cavity of the clavicle].

PMID- 4346215
TI  - The responses in culture of human tumour astrocytes and neuroblasts to N 6 , O 2'
      -dibutyryl adenosine 3',5'-monophosphoric acid.

PMID- 4346216
TI  - Thiamin deficiency: liver metabolite levels and redox and phosphorylation states
      in thiamin-deficient rats.

PMID- 4346217
TI  - Vitamin A and bone metabolism in the rat.

PMID- 4346218
TI  - Malignant lymphoma and nephrotic syndrome. A clinicopathologic analysis with
      light, immunofluorescence, and electron microscopy of the renal lesions.

PMID- 4346219
TI  - Malignant mixed mullerian tumor of the cervix following cyclophosphamide therapy
      for nephrotic syndrome.

PMID- 4346220
TI  - Hyperthyroidism induced by trophoblastic thyrotropin.

PMID- 4346221
TI  - New drugs for treatment of Paget's disease.

PMID- 4346222
TI  - Diplovax. A new oral polio vaccine.

PMID- 4346223
TI  - Inactivation of Q beta RNA by electrophiles.

PMID- 4346224
TI  - Genetical behaviour of vesicular stomatitis virus during successive passages at
      high and low temperatures.

PMID- 4346225
TI  - Genetic analysis of replicating instabilities in yeast.

PMID- 4346226
TI  - Cytogenetic and mutagenic effects of DDT and DDE in a Chinese hamster cell line.

PMID- 4346227
TI  - Cytogenetic effects of hycanthone in the rat.

PMID- 4346228
TI  - Demonstration by electron microscopy of viruses in cells found by light
      microscopy to contain inclusion bodies.

PMID- 4346229
TI  - Long survival in a male with 18-trisomy syndrome and Wilms' tumor: a subsequent
      report.

PMID- 4346230
TI  - Role of adenosine 3',5'-monophosphate (cyclic AMP) in actions of catecholamines.

PMID- 4346231
TI  - Effect of angiotensin II on arterial blood pressure, glomerular filtration rate
      and urinary sodium excretion in normal, pregnant and hypertensive rats.

PMID- 4346232
TI  - [Hypothalamo-hypophysiotrapic hormones. 2].

PMID- 4346233
TI  - Percutaneous adrenal venography in the dog.

PMID- 4346234
TI  - The all-ulnar hand.

PMID- 4346235
TI  - Parametric evaluation of the prevalence of Entamoeba histolytica infections in
      Ibadan.

PMID- 4346236
TI  - [Pain and its ways of expression].

PMID- 4346237
TI  - The fine structure of the sporozoites of Isospora canis.

PMID- 4346238
TI  - Ultrastructural study of microsporidian invasion into cells.

PMID- 4346239
TI  - Study on parainfluenza virus type 1 isolated from pigs.

PMID- 4346240
TI  - Vitamin D-resistant rickets and hemophilia A--lack of close linkage on the X
      chromosome.

PMID- 4346241
TI  - Variability of  -galactosidase A and B in different tissues of man.

PMID- 4346242
TI  - The effects of gallamine on nerve terminals and endplates.

PMID- 4346243
TI  - [Metabolism of malignant melanomas. Biochemical studies].

PMID- 4346244
TI  - [Immunological studies in herpes simplex].

PMID- 4346245
TI  - [Clinical aspects and diagnosis of the "anal and rectal carcinoma"].

PMID- 4346246
TI  - [Intercellular junctions of connective tissue cells].

PMID- 4346247
TI  - The mechanism of inhibition by fluoride of mitochondrial fatty acid oxidation.

PMID- 4346248
TI  - Factors controlling the rate of fatty acid  -oxidation in rat liver mitochondria.

PMID- 4346249
TI  - Cyclic 3',5'-adenosine monophosphate-dependent protein kinase of skin. I.
      Measurement and properties.

PMID- 4346250
TI  - Cyclic 3',5'-adenosine monophosphate-dependent protein kinase of skin. II. Levels
      in atopic dermatitis and psoriasis.

PMID- 4346251
TI  - [Peroperative measurement of the blood sugar in surgery of hypoglycemic islet
      cell adenomas].

PMID- 4346252
TI  - [A further case of Krukenberg's tumor manifesting a vesiculo-choledochal cancer].

PMID- 4346253
TI  - [Hypoglycemic islet cell adenoma in children. Apropos of 2 cases].

PMID- 4346254
TI  - Virus studies in the treatment of congenital cytomegalovirus infections by
      cytosine arabinoside.

PMID- 4346255
TI  - Determination of the molecular weight of human gamma-3 chains by polyacrylamide
      gel electrophoresis in the presence of sodium dodecyl sulphate.

PMID- 4346257
TI  - The persistence of tissue-specific antigen in muscle cells growing in vitro.

PMID- 4346256
TI  - The effect of anti-lymphocytic antibody on the humoral immune response in
      different strains of mice. I. The response to bovine serum albumin.

PMID- 4346258
TI  - Dissociation of single cells from lung or kidney tissue with elastase.

PMID- 4346260
TI  - Adrenocorticotropin. 43. The synthesis and steroidogenic activity of (2-N
      methylphenylalanine)-adrenocorticotropin-(1-19).

PMID- 4346259
TI  - A simple interferon assay as an adjunct for determining the genus of origin of
      cell cultures.

PMID- 4346261
TI  - Studies on L-glycerol-3-phosphate dehydrogenases in Japanese quail, Coturnix
      coturnix japonica. I. Multiple components and some enzymatic properties of
      nicotinamide adenine dinucleotide-linked L-glycerol-3-phosphate dehydrogenase
      from liver and testes.

PMID- 4346262
TI  - The purification and properties of geranylgeranyl pyrophosphate synthetase from
      pumpkin fruit.

PMID- 4346263
TI  - Vertebrate collagenase: direct extraction from animal skin and human synovial
      membrane.

PMID- 4346265
TI  - Studies on N-Acetyl- -D-glucosaminidase of Aspergillus oryzae. 3.
      Transglycosylation by the enzyme and preparation of crystalline phenyl N, N'
      diacetyl- -chitobioside.

PMID- 4346264
TI  - Reconstitution of hepatic microsomal stearoyl-coenzyme A desaturase system from
      solubilized components.

PMID- 4346266
TI  - Acetanilide-hydrolyzing esterase of rat liver microsomes. I. Solubilization,
      purification, and intramicrosomal localization.

PMID- 4346268
TI  - [Inhibition of uterine contraction. Several aspects and relationships with cyclic
      AMP].

PMID- 4346267
TI  - Enzyme kinetics and its relevance to enzyme assay.

PMID- 4346269
TI  - The effect of neonatal and adult thymectomy on the inflammatory response.

PMID- 4346270
TI  - The digestion of cellular fragments within phagolysosomes in carcinoma cells.

PMID- 4346271
TI  - A comparative histochemical study of rat livers in alpha-naphthyl-iso-thiocyanate
      (ANIT) and DL-ethionine intoxication.

PMID- 4346272
TI  - Prostaglandins and reproduction.

PMID- 4346273
TI  - Multilocular renal cystic disease in children.

PMID- 4346274
TI  - An approach to metastatic nephroblastoma.

PMID- 4346275
TI  - The radiologic discrimination of abdominal masses in infants.

PMID- 4346276
TI  - Localization of adrenal tumors by photoscanning.

PMID- 4346277
TI  - Aspects of the encapsidation of simian virus 40 deoxyribonucleic acid.
AB  - Growing subcloned CV1-cells were infected with simian virus 40, and the time
      course of virus formation was determined. When infected cells were fractionated
      into cytoplasmic and nuclear fractions, most of the progeny virus particles were
      recovered in the cytoplasmic extract and not in the nuclei. This result was
      independent of the technique used for the preparation of nuclei and of the time
      after infection at which the extracts were prepared. Leakage of the virions from
      the nucleus occurred during the course of cell fractionation, suggesting that the
      nuclear membrane of the infected cells is damaged. Virions were found to
      accumulate in a nonlinear fashion, at the time when the number of viral
      deoxyribonucleic acid (DNA) molecules increases linearly with time after
      infection. This suggests that the size of the intracellular pool of capsid
      proteins increases constantly during the late phase of virus replication. Progeny
      viral DNA to become encapsidated is withdrawn at random from the pool of
      replicated DNA molecules.

PMID- 4346278
TI  - Viruses of Entamoeba histolytica. 3. Properties of the polyhedral virus of the HB
      301 strain.
AB  - Some biological characteristics and bioassay of a polyhedral virus isolated from
      normal-appearing strain HB-301 of Entamoeba histolytica are described. The virus
      produced lysis of susceptible strains of E. histolytica, yet it caused no
      cytopathological effect in the host strain, HB-301. The virus and host amoeba
      existed in an equilibrium; approximately 10(4) mean infective dose units of virus
      were produced per million HB-301 amoebae. Superinfection and antiviral antiserum
      treatment failed to disturb this equilibrium permanently. The mechanism of viral
      persistence in strain HB-301 amoebae remains to be determined. Purification of
      the virus was attempted. Ninety-nine percent of the viral infectivity was
      associated with a low-speed pellet which consisted of complexes of virus and
      cellular membranes. Various treatments of this low-speed pellet failed to release
      virus. Biologically active, membrane-free virus of low titer was prepared by
      differential centrifugation of supernatant solutions and employed in electron
      microscopy and other studies.

PMID- 4346279
TI  - Molecular weights of vesicular stomatitis virus and its defective particles by
      laser light-scattering spectroscopy.
AB  - Laser light-scattering spectroscopy has been used to determine the diffusion
      coefficients of vesicular stomatitis virus and three of its defective particles
      in order to calculate their molecular weights.

PMID- 4346280
TI  - Replication of the Moloney murine sarcoma-leukemia virus in XC cells.
AB  - The XC rat cell line was found to support the replication of a strain of the
      Moloney murine sarcoma-leukemia virus. In growth curve experiments cytopathology
      was paralleled by the production of murine sarcoma virus and leukemia virus
      progeny having the biologic, antigenic, and biophysical properties of the
      infecting virus.

PMID- 4346281
TI  - Patterns of simian virus 40 deoxyribonucleic acid transcription. II. In
      transformed cells.
AB  - The pattern of simian virus 40 (SV40) deoxyribonucleic acid transcription has
      been examined in 11 SV40-transformed cell lines. In all cases, substantial
      regions of the minus strand (35-75%) appeared to be transcribed. In the lines
      tested, these regions included the "early" gene sequences. The SV40-specific
      ribonucleic acid from at least two of the transformed cell lines represented
      significantly greater portions of the minus strand than are represented in
      "early" lytic ribonucleic acid. Small regions of the plus strand appeared to be
      transcribed in only two of the transformed cell lines.

PMID- 4346282
TI  - Replication of simian virus 40 deoxyribonucleic acid: analysis of the one-step
      growth cycle.
AB  - The time course of replication of simian virus 40 deoxyribonucleic acid (DNA) was
      investigated in growing monolayer cultures of subcloned CV1 cells. At
      multiplicities of infection of 30 to 60 plaque-forming units (PFU)/cell, first
      progeny DNA molecules (component 1) were detected by 10 hr after infection.
      During the following 10 to 12 hr, accumulation of virus DNA proceeded at ever
      increasing rates, albeit in a non-exponential fashion. The rate of synthesis then
      remained constant, until approximately the 40th hour postinfection, when DNA
      replication stopped. Under these conditions, the duration of the virus growth
      cycle was approximately 50 hr. The time needed for the synthesis of one DNA
      molecule was found to be approximately 15 min. At multiplicities of infection of
      1 or less than 1 PFU/cell, the onset of the linear phase of DNA accumulation was
      delayed, but the final rate of DNA synthesis was the same, independent of the
      input multiplicity. This was taken as a proof that templates for the synthesis of
      viral DNA multiply in the cell during the early phase of replication. However,
      the probability for every replicated DNA molecule to become in turn replicative
      decreased constantly during that phase. This could be accounted for by assuming a
      limited number of replication sites in the infected cell.

PMID- 4346283
TI  - Oral contraceptives and breast histology.

PMID- 4346284
TI  - [Hepatoma in cirrhosis. Serum alpha-feto-protein levels after hepatic
      dearterialization].

PMID- 4346285
TI  - [Medical treatment of Crohn's disease].

PMID- 4346286
TI  - [Results of nuclear medical and neuroradiological studies in postoperative brain
      tumor recurrences].

PMID- 4346287
TI  - Denmark's geriatric patients: community care and after-care.

PMID- 4346288
TI  - I-cell disease: biochemical studies.

PMID- 4346290
TI  - [Sequence determination of oligonucleotides].

PMID- 4346289
TI  - [Purification and assay of cAMP receptor protein].

PMID- 4346291
TI  - [Immunology in dermatology].

PMID- 4346292
TI  - A case of encephalopathic, myelopathic, and peripheral nerve dysfunction in
      folate deficient megaloblastic anemia.

PMID- 4346293
TI  - Mycoplasma species in association with feline viruses.

PMID- 4346294
TI  - Studies of the mechanism of induction of infectious murine leukemia virus from
      AKR mouse embryo cell lines by 5-iododeoxyuridine and 5-bromodeoxyuridine.

PMID- 4346295
TI  - The induction of interferon by temperature-sensitive mutants of reovirus, UV
      irradiated reovirus, and subviral reovirus particles.

PMID- 4346296
TI  - Enucleation of cells made simple and rescue of SV40 by enucleated cells made even
      simpler.

PMID- 4346297
TI  - The effect of dibutyryl cyclic AMP on transformation by oncogenic viruses.

PMID- 4346298
TI  - Isolation of leukosis-type virus from pheasant embryo cells: possible presence of
      viral genes in cells.

PMID- 4346299
TI  - Characterization of the SV40 T antigen.

PMID- 4346300
TI  - [Effect of theophylline on the gastric secretion stimulated by gastrin].

PMID- 4346302
TI  - [Glucose-6-phosphatase and fructose-1,6-diphosphatase in the young porcine liver
      during postnatal development].

PMID- 4346301
TI  - [Functional criteria of inner-membrane-fractions from rat liver mitochondria. I.
      Digitonin particles].

PMID- 4346303
TI  - Effects of aircraft noise on human sleep.

PMID- 4346304
TI  - Active transport of calcium ion in sarcoplasmic membranes.

PMID- 4346305
TI  - Linear analysis of the dynamics of neural masses.

PMID- 4346306
TI  - The mechanism of signal transmission in nerve axons.

PMID- 4346308
TI  - [Collagenolytic activity in healthy and experimentally damaged rat bone].

PMID- 4346307
TI  - Plasticity of biological membranes.

PMID- 4346309
TI  - Isolation and characterization of agglutinin receptor sites. 3. Studies on the
      interaction with other lectins.

PMID- 4346310
TI  - The interaction of a lytic peptide, melittin, with spin-labeled membranes.

PMID- 4346311
TI  - Binding and aggregate formation of phospholipid liposomes containing phosphatidic
      acid with ovalbumin.

PMID- 4346312
TI  - Turnover of rat liver plasma membrane phospholipids comparison with microsomal
      membranes.

PMID- 4346313
TI  - Subcellular fractionation of human lymphocytes. Isolation of two plasma membrane
      fractions and comparison of the protein components of the various lymphocytic
      organelles.

PMID- 4346314
TI  - Immunity of Epstein-Barr virus in Hodgkin's disease preceded by infectious
      mononucleosis.
AB  - A patient who developed Hodgkin's disease four years after infectious
      mononucleosis had elevated serum antibody titres to Epstein-Barr virus and
      delayed hypersensitivity reactions to membrane antigens prepared from fresh
      autologous spleen, from spleen cells of another Hodgkin's patient, and from cell
      lines known to carry the Epstein-Barr virus genome. Additional studies in more
      lymphoma patients will be needed to determine the significance of the reactivity
      against tumour and virus-associated antigens which has been documented in this
      patient.

PMID- 4346315
TI  - Herpes zoster of the vulva.

PMID- 4346316
TI  - Effect of systemic maternal virus infections on the fetus and newborn.

PMID- 4346317
TI  - The laboratory diagnosis of virus infections in gynecology and obstetrics.

PMID- 4346318
TI  - Herpes genitalis: clinical features.

PMID- 4346319
TI  - Herpes genitalis: venereal aspects.

PMID- 4346320
TI  - Relation of herpesvirus type 2 to carcinoma of the cervix.

PMID- 4346321
TI  - Significance of herpes simplex virus infection during pregnancy.

PMID- 4346323
TI  - Cytomegalovirus infections in the pregnant female and the newborn infant.

PMID- 4346322
TI  - Herpes genitalis: management--present and predicted.

PMID- 4346324
TI  - [Avoidable diagnostic errors in radiography of the female breast.
      (Mammographies)].

PMID- 4346326
TI  - Surface glycoproteins of cells before and after transformation by oncogenic
      viruses.

PMID- 4346327
TI  - Glycolipid synthesis and tumorigenicity of clones isolated from the Nil 2 line of
      hamster embryo fibroblasts.

PMID- 4346325
TI  - Membrane components and enzymes in virally transformed cells.

PMID- 4346328
TI  - Surface changes in transformed cells detected by lectins.

PMID- 4346330
TI  - Adrenocorticotropic activity in vitro of the chick embryo pituitary gland.

PMID- 4346329
TI  - Studies on the specificity of the radio-bioassay for corticotrophin.

PMID- 4346331
TI  - The mechanism of cell fusion. II. Formation of chicken erythrocyte polykaryons.

PMID- 4346332
TI  - Purification and properties of a protein kinase from bovine corpus luteum that is
      stimulated by cyclic adenosine 3',5'-monophosphate and luteinizing hormone.

PMID- 4346333
TI  - New complexes of peroxidases with hydroxamic acids, hydrazides, and amides.

PMID- 4346335
TI  - Kinetics of electron transfer between cardiac cytochrome c 1  and c.

PMID- 4346334
TI  - Regulation of biodegradative threonine deaminase. I. Allosteric inhibition of the
      enzyme by a reaction product and its reversal by adenosin 5'-monophosphate.

PMID- 4346336
TI  - Studies on heart phosphofructokinase. Role of fructose 1,6-diphosphate in enzyme
      activity.

PMID- 4346337
TI  - Purification and properties of the protein activator of bovine heart cyclic
      adenosine 3',5'-monophosphate phosphodiesterase.

PMID- 4346339
TI  - A novel sialic acid and fucose-containing disaccharide isolated from the jelly
      coat of sea urchin eggs.

PMID- 4346338
TI  - Light-stimulated phosphorylation of bovine visual pigments by adenosine
      triphosphate.

PMID- 4346340
TI  - Spectroscopic evidence for a difference between the iron-binding sites of
      conalbumin.

PMID- 4346341
TI  - The elongation factor 2 content of mammalian cells. Assay method and relation to
      ribosome number.

PMID- 4346342
TI  - Mammalian deoxyribonucleic acid ligase. Isolation of an active enzyme-adenylate
      complex.

PMID- 4346343
TI  - Binding of testosterone to uterine components of the immature rat.

PMID- 4346344
TI  - Regulation and mechanism of phosphoribosylpyrophosphate synthetase. V. Inhibition
      by end products and regulation by adenosine diphosphate.

PMID- 4346345
TI  - Evidence against two "pH locked" conformations of phosphorylated trypsin.

PMID- 4346346
TI  - Activation of muscle fructose 1,6-diphosphatase by creatine phosphate and
      citrate.

PMID- 4346347
TI  - Electron spin resonance of  63 Cu and  65 Cu carbonic anhydrases. Resolution of
      nitrogen ligand superhyperfine structure.

PMID- 4346348
TI  - Gluconeogenesis in rabbit liver. I. Pyruvate-derived dicarboxylic acids and
      phosphoenolpyruvate formation in rabbit liver.

PMID- 4346349
TI  - Sodium-potassium-activated adenosine triphosphatase of Electrophorus electric
      organ. 8. Monovalent cation sites regulating phosphatase activity.

PMID- 4346351
TI  - Lipid-protein interactions in the reconstitution of the microsomal reduced
      nicotinamide adenine dinucleotide-cytochrome b 5  reductase system.

PMID- 4346350
TI  - A form of reduced nicotinamide adenine dinucleotide-cytochrome b 5   reductase
      containing both the catalytic site and an additional hydrophobic membrane-binding
      segment.

PMID- 4346352
TI  - Anomalous ligand binding by a class of high spin c-type cytochromes.

PMID- 4346353
TI  - Adrenal gland in vitamin E deficiency. 3. Inhibition of adrenocorticotropic
      hormone-induced steroidogenesis in isolated adrenal cells by ascorbic acid.

PMID- 4346354
TI  - Cyclic adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices. I.
      Formation of cyclic adenosine 3',5'-monophosphate from endogenous adenosine
      triphosphate and from radioactive adenosine triphosphate formed during a prior
      incubation with radioactive adenine.

PMID- 4346355
TI  - Sodium-potassium-activated adenosine triphosphatase. IX. The role of
      phospholipids.

PMID- 4346356
TI  - Properties of adenosine 3',5'-monophosphate-dependent protein kinases isolated
      from bovine epididymal spermatozoa.

PMID- 4346357
TI  - Chemical sympathectomy and avoidance learning in the rat.

PMID- 4346358
TI  - Femoral neuropathy due to haemorrhage into iliacus muscle.

PMID- 4346359
TI  - Plasma cortisol.

PMID- 4346360
TI  - Plasma cortisol level in normal Indian subjects and its variation in disease.

PMID- 4346361
TI  - A clinicopathological study of synovial sarcoma.

PMID- 4346362
TI  - [IgM-latex-test as screening procedure for pre- and perinatal infections].

PMID- 4346363
TI  - [Thymus gland hyperplasia: congenital, in association with adrenal gland
      hypoplasia and cytomegaly or myocarditis respectively].

PMID- 4346364
TI  - The angiographic appearance of nasopharyngeal carcinoma.

PMID- 4346365
TI  - Studies on the adrenocortical hormone therapy in idiopathic nephrotic syndrome in
      children.

PMID- 4346366
TI  - [Exanthemas and skin test reactions to penicillanic acid derivatives ampicillin
      and ciclacillin].

PMID- 4346367
TI  - Principles of brain scan interpretation.

PMID- 4346368
TI  - Radioimmunoassay of angiotensin and determination of renin activity.

PMID- 4346369
TI  - Selective angiography in localizing islet-cell tumors of the pancreas. A further
      appraisal.

PMID- 4346371
TI  - Arteriographic findings in synovial hemangioma of the knee.

PMID- 4346370
TI  - Parasitic blood supply of neoplasms. Mechanisms and significance.

PMID- 4346372
TI  - Multilocular cyst of the kidney. A case report with angiographic findings.

PMID- 4346373
TI  - Radiotherapy in chest malignant tumors associated with pulmonary tuberculosis.

PMID- 4346374
TI  - Massive hemoperitoneum from rupture of benign hepatocellular adenoma.

PMID- 4346375
TI  - [Asthma and asthma care].

PMID- 4346376
TI  - [Acromegaly].

PMID- 4346377
TI  - [Pyrophosphate arthritis--a rare condition?].

PMID- 4346378
TI  - [Antigen therapy of recurring herpes simplex with herpes simplex vaccine LUPIDON
      H and G].

PMID- 4346379
TI  - Changes of immunologic competence of lymphocytes evaluated by phytohemagglutinin
      (PHA)-induced DNA synthesis related to pregnancy and gynecologic tumors.

PMID- 4346380
TI  - Establishment of Entamoeba histolytica from liver abscess in monoxenic cultures
      with hemoflagellates.

PMID- 4346383
TI  - Long-term results of therapy of glomus jugulare tumors.

PMID- 4346381
TI  - Herpes zoster dendritic keratitis.

PMID- 4346382
TI  - Radiation therapy of glomus jugulare tumors.

PMID- 4346384
TI  - Brain microsomal protein kinase in the chronically morphinized rat.

PMID- 4346385
TI  - Accelerated turnover rate of nicotinamide-adenine dinucleotides in the liver of
      rats intoxicated with carbon disulphide.

PMID- 4346386
TI  - Effects of tubercidin and its ribonucleotides on various metabolic pathways in
      Schistosoma mansoni.

PMID- 4346387
TI  - Kininase activity in equine plasma.

PMID- 4346388
TI  - Reducibility of cytochromes b in aerobic beef-heart mitochondria treated with
      antimycin.

PMID- 4346389
TI  - Oxidoreduction of cytochrome b in the presence of antimycin.

PMID- 4346390
TI  - Quantitative EPR studies of the primary reaction of photosystem I in
      chloroplasts.

PMID- 4346391
TI  - The reduction mechanism of ferricytochrome c.

PMID- 4346392
TI  - [Aspects of differential diagnosis and diagnostic errors in chronic diarrhea.
      Verner-Morrison syndrome, gluten induced enteropathies, laxative abuse].

PMID- 4346393
TI  - [Esophageal duplication].

PMID- 4346394
TI  - [Transient pyloric stenosis in intermittent stomach volvulus].

PMID- 4346395
TI  - [Unclarified symptom of gastric stump following gastrectomy].

PMID- 4346396
TI  - [Pseudotumorous enlargement of mediastinal adipose tissue in Cushing's disease].

PMID- 4346397
TI  - [Centennial of Professor Dr. G. Holzknecht's birthday].

PMID- 4346398
TI  - [In memoriam Willy Baensch].

PMID- 4346399
TI  - [Reticuloblastomatoses of the stomach].

PMID- 4346400
TI  - [Benign laryngeal diseases in the tomogram].

PMID- 4346401
TI  - [Visceral and bone involvement in giant follicular lympho-blastoma (Brill
      Symmers)].

PMID- 4346402
TI  - [Unilateral pulmonary vascular hypoplasia in mitral stenosis].

PMID- 4346403
TI  - [Diagnosis of recurring ulcer following pyloromyoplasty].

PMID- 4346404
TI  - [Gastroesophageal reflux].

PMID- 4346405
TI  - [Radiological diagnosis of swelling in the elbow joint].

PMID- 4346406
TI  - [Rare developmental abnormalities of the mesoderm involving the extremities].

PMID- 4346407
TI  - [Band-like osteolysis of the terminal phalanges of the hands].

PMID- 4346408
TI  - [Splenic rupture in the scintigram].

PMID- 4346410
TI  - [ 133 Xe arthrography for synovitis of the knee joint].

PMID- 4346409
TI  - [Computer demonstration of a finger cross section in bone density measurement
      using a  125 I profile scanner].

PMID- 4346411
TI  - [Isotope arteriography for arterial occlusive disease of the lower extremities].

PMID- 4346413
TI  - [Use of a television picture storage device with a semiconductor storage tube in
      radiographic technology].

PMID- 4346412
TI  - [Studies of  131 I fibrinogen storage by the Yoshida sarcoma of rats].

PMID- 4346414
TI  - [Development of internal carotid artery occlusion following craniocerebral
      injury].

PMID- 4346415
TI  - [Rare association of primitive persistent trigeminal artery with acoustic
      neurinoma].

PMID- 4346416
TI  - [Histogenesis of nevus comedonicus. Histochemical, light and electron microscopy
      studies].

PMID- 4346418
TI  - [Enzyme histochemical findings in the glial layer of the developing rat brain].

PMID- 4346419
TI  - Factors influencing induction and duration of oculomotor reflex rebound in the
      guinea pig.

PMID- 4346420
TI  - Effect of dexamethasone on affective behavior and adrenal reactivity following
      septal lesions in the rat.

PMID- 4346421
TI  - Granular cell myoblastoma of the bronchus. Report of two cases, one diagnosed by
      exfoliative cytology.

PMID- 4346417
TI  - Further enzyme histochemical observations on the segmentation of the proximal
      tubules in the kidney of the male rat.

PMID- 4346422
TI  - Activity of plasma angiotensin II in experimental coarctation of the aorta.

PMID- 4346424
TI  - [Postnatal growth of head circumference in preterm and full term infants].

PMID- 4346425
TI  - [Mammo-renal syndrome].

PMID- 4346423
TI  - [Surgical treatment of 300 cases of aortic coarctation].

PMID- 4346426
TI  - [Important advances in bone scintigraphy by use of technetium pyrophosphate (99m
      Tc)].

PMID- 4346427
TI  - Activities of certain enzymes of glycolytic pathway in normal, chronic cervicitis
      and malignant human cervix uteri.

PMID- 4346428
TI  - Quantitation of RNA tumor viruses and viruslike particles in human milk by
      hybridization to polyadenylic acid sequences.
AB  - RNA tumor viruses and viruslike particles from human milk are quantitated by
      hybridization of the polyadenylic acid regions in their 60S to 70S RNA to
      radioactive polyribouridylic acid of known specific activity. The length of the
      polyadenylic acid region in the 60S to 70S RNA of the human milk particle is
      identical to that of the known oncogenic RNA viruses.

PMID- 4346429
TI  - [Aldolase, acid phosphatase and prostatic phosphatase in the blood of patients
      with prostatic cancer].

PMID- 4346430
TI  - [Influence of the degree of impendance change on the temporary threshold shift].

PMID- 4346432
TI  - Review of canine viral disease.

PMID- 4346431
TI  - Recovery of infectious canine hepatitis virus from dogs with different clinical
      syndromes.

PMID- 4346433
TI  - Studies on the reconstituion of bovine erythrocyte superoxide dismutase. 3.
      Evidence for a strong interdependence between Cu 2+  and Zn 2+  binding in the
      expression of the spectroscopic properties of the native protein and for a close
      proximity of the Zn 2+  and Cu 2+  sites.

PMID- 4346434
TI  - On the physiological role of   2 -macroglobulin.

PMID- 4346435
TI  - The isolation and properties of pig plasma lipoproteins and partial
      characterisation of their apoproteins.

PMID- 4346436
TI  - Evidence for intramolecular crosslinks in chicken bone collagen: the isolation of
      peptides containing allysine aldol.

PMID- 4346437
TI  - Environment of the iron-sulfur chromophore in adrenodoxin studied by EPR and
      ENDOR spectroscopy.

PMID- 4346438
TI  - Studies on the reconstitution of bovine erythrocyte superoxide dismutase. I. The
      presence of four divalent metal-binding sites on the apo protein which are
      different from the native sites.

PMID- 4346439
TI  - Interactions of bovine serum albumin with penicillins and cephalosporins studied
      by pulse radiolysis.

PMID- 4346440
TI  - Studies on the reconstitution of bovine erythrocyte superoxide dismutase. II.
      Some observations on the nature of catalyzed superoxide anion dismutation as an
      enzymatic activity.

PMID- 4346441
TI  - Synaptic transmission in the submandibular ganglion of the rat.

PMID- 4346442
TI  - [Effect of acid pH on induction of an activiral resistance condition by
      interferon].

PMID- 4346443
TI  - [Quantitative changes in sphingomyelin and diphosphatidylglycerol after viral
      transformation of cells].

PMID- 4346444
TI  - [Relations between rapidity of learning and paradoxical sleep duration during the
      nycthemeral cycle in rats].

PMID- 4346445
TI  - [Electrophoretic study of structural glycoproteins extracted from rabbit
      hypodermis].

PMID- 4346446
TI  - [Effect of cyclic AMP on spontaneous rosette forming cells].

PMID- 4346447
TI  - Areexamination of phase IV Bordetella pertussis.

PMID- 4346448
TI  - Ultrastructure of Filobasidium Olive.

PMID- 4346449
TI  - Growth and ultrastructural differentiation of sporangia in Phytophthora
      palmivora.

PMID- 4346450
TI  - [Neoplastiform aspects of pigmented villonodular synovitis].

PMID- 4346451
TI  - [Gonosome complement and growth disorders in gonadal dysgenesis with female
      phenotype].

PMID- 4346452
TI  - [Influence of ACTH and metopirone on the excretion of cortisol metabolites in
      endogenous depression during thioridazine administration].

PMID- 4346453
TI  - Effect of some adenosine 3',5'-monophosphate analogues on cell proliferation,
      tumor growth and macromolecular synthesis in various organs of the mouse.

PMID- 4346454
TI  - [Significance of 3',5'-cyclic AMP in the gastric secretion of the rat].

PMID- 4346455
TI  - [Mechanism of fatty acid elongation in arterial tissue during oxygen deficiency].

PMID- 4346456
TI  - [Influence of the phorbol ester TPA on the beta adrenergic activation of
      epidermal adenylcyclase and the cAMP level in the mouse epidermis].

PMID- 4346457
TI  - [Biosynthesis of D-apiose and D-xylose in parsley and Lemma minor and their
      regulation through light].

PMID- 4346458
TI  - [Lactate metabolism of isolated kidney tubules and interconversion of pyruvate
      dehydrogenase (PHD)].

PMID- 4346459
TI  - [Comparison of phosphorylase-b-kinase from frog and rabbit muscle].

PMID- 4346460
TI  - [Smallpox-virus-specific early function in interferon-treated cells:
      transcription and processing of smallpox virus specific early mRNA].

PMID- 4346461
TI  - [Isolation and characterization of a new T4-induced nuclease].

PMID- 4346462
TI  - [Relaxation kinetic studies on glutamate dehydrogenase (GluDH)].

PMID- 4346463
TI  - [Immediate regulation manifestations following glucose feeding in Saccharomyces
      carlsbergensis].

PMID- 4346464
TI  - [Phenylalanyl-tRNA synthetase (PRS) from Escherichia coli: binding of substrates
      and effectors].

PMID- 4346465
TI  - [Differentiation between 2 cytochrome-a-components, 3 cytochrome-b-components and
      hemoglobin in yeast cells].

PMID- 4346466
TI  - [Kinetic studies on binding of effectors to glutamate-dehydrogenase].

PMID- 4346467
TI  - Modification of yeast tyrosine tRNA with N-acetoxy-2-acetylaminofluorene.

PMID- 4346468
TI  - The conversion of ornithine to proline: compartmentation of enzymes between
      cytoplasm and mitochondria.

PMID- 4346469
TI  - [Abolition of polarity in an in-vitro system for enzymes of the galactose
      operon].

PMID- 4346470
TI  - [Properties of the trypsin-like (acrosin) from boar spermatozoa].

PMID- 4346471
TI  - Multiple steroid hormone receptors in calf uterus. Binding specificities and
      distribution.

PMID- 4346472
TI  - Activity of some actinomycetes and high plants against foot and mouth disease
      virus.

PMID- 4346473
TI  - Biological defense mechanisms. The production by leukocytes of superoxide, a
      potential bactericidal agent.
AB  - As a highly reactive substance produced in biological systems by the one-electron
      reduction of oxygen, superoxide (O(2) (-)) seemed a likely candidate as a
      bactericidal agent in leukocytes. The reduction of cytochrome c, a process in
      which O(2) (-) may serve as an electron donor, was found to occur when the
      cytochrome was incubated with leukocytes. O(2) (-) was identified as the agent
      responsible for the leukocyte-mediated reduction of cytochrome c by the
      demonstration that the reaction was abolished by superoxide dismutase, an enzyme
      that destroys O(2) (-), but not by boiled dismutase, albumin, or catalase.
      Leukocyte O(2) (-) production doubled in the presence of latex particles. The
      average rate of formation of O(2) (-) in the presence of these particles was 1.03
      nmol/10(7) cells per 15 min. This rate, however, is only a lower limit of the
      true rate of O(2) (-) production, since any O(2) (-) which reacted with
      constituents other than cytochrome c would have gone undetected. Thus. O(2) (-)
      is made by leukocytes under circumstances which suggest that it may be involved
      in bacterial killing.

PMID- 4346474
TI  - [Comparative study of the organization of spontaneous thalamic neuronal discharge
      in awakened condition and MOP (Macaca speciosa)].

PMID- 4346475
TI  - [Effect of L-dopa upon transmission in ascending propriospinal pathways of cats].

PMID- 4346477
TI  - [Evaluation of vasopressin and enzymologic changes in the hypothalamo
      neurohypophyseal system of rats after adrenalectomy].

PMID- 4346478
TI  - [Experimental asthma in guinea pigs and autonomic mediators].

PMID- 4346476
TI  - [Messenger role of 3'5' adenosine monophosphoric acid (cyclic AMP) in the action
      of somatotropic hormone on the uptake of 14C glucose by the diaphragm of
      hypophysectomized rats].

PMID- 4346480
TI  - [Paradoxical sleep and memorizing: effect of the delay of falling asleep in
      rats].

PMID- 4346479
TI  - [Electric synapses in a mammal: electrotonic coupling between giant neurons of
      Deiters' nucleus in rats].

PMID- 4346481
TI  - [Effect of CO 2  upon physical characteristics of the motoneural membrane].

PMID- 4346483
TI  - [Electrophysiologic detection of cutaneous intraspinal primary relays. Study of
      the functional role of primary interneurons].

PMID- 4346482
TI  - [Calcic response and cholinergic sensitivity at the neuromuscular junction].

PMID- 4346484
TI  - [Effect of abnormal anions upon frog striated muscular fiber, detubulated by
      osmotic shock].

PMID- 4346485
TI  - [Early and late effects of the removal of different cortical areas upon the
      evolution of the P wave of dorsal spinal cord potential during the wake-sleep
      cycle in cats].

PMID- 4346486
TI  - [Effect of the corticotropic hormone on amygdaloventromedian pathways in awaked
      free rabbits].

PMID- 4346487
TI  - [Effect of different lighting conditions on the distribution of free amino acids
      in the retina during development].

PMID- 4346488
TI  - [Phases of paradoxical sleep in the isolated brain preparation. Their releasing
      by vagoarotic stimulation].

PMID- 4346489
TI  - [Mechanism of heterosynaptic facilitation in Aplysia].

PMID- 4346490
TI  - [What would be your diagnosis?].

PMID- 4346492
TI  - [Function of the dream and the psychopathology of sleep in children].

PMID- 4346491
TI  - [Physiology of sleep in children].

PMID- 4346493
TI  - [Sleep--hallucinations and experimental model].

PMID- 4346494
TI  - [Narcolepsy].

PMID- 4346495
TI  - [Nightmares].

PMID- 4346496
TI  - Measles giant cell pneumonia without rash in a case of lymphocytic lymphosarcoma.
      An electron microscopic study.

PMID- 4346497
TI  - [Duration of the after-control of the tuberculous patients following the
      termination of the treatment].

PMID- 4346498
TI  - [Infectivity of various protozoan species after extended storage in liquid
      nitrogen].

PMID- 4346499
TI  - [The hydrochemical living conditions of the immature stages of Boophthora
      erythrocephala De Greer (Diptera, Simuliidae). 1. Field studies].

PMID- 4346500
TI  - Ultimobranchial gland ultrastructure of larval axolotls, Ambystoma mexicanum
      Shaw, with some observations on the newt, Pleurodeles waltlii Micahelles.

PMID- 4346501
TI  - [Canaliculi cells and dark cells in the nephron of anurans].

PMID- 4346502
TI  - Ultrastructural studies on the hypothalamic neurosecretory neurons of the rat.
      II. The hypothalamo-neurohypophysial system in rats with hereditary hypothalamic
      diabetes insipidus.

PMID- 4346503
TI  - [The calcium cells of the connective tissue in Ferrissia wautieri (Moll.
      Ancylidae). Description, mineralogy and seasonal variations].

PMID- 4346504
TI  - Ultrastructure of the hepatopancreas and associated tissues of the chelicerate
      arthropod, Limulus polyphemus.

PMID- 4346505
TI  - Gas secreting cells in the rear chamber of the swimbladder of the pond-loach,
      Misgurnus fossilis L. An electron microscopic study.

PMID- 4346506
TI  - [Degeneration of the pineal nerve of Rana esculenta L. following frontal-organ
      proximal and distal transection].

PMID- 4346507
TI  - Disturbance of blood glucose regulation in pertussis sensitized rats.

PMID- 4346508
TI  - Semisynthetic penicillins. IX. Thiophene compounds related to oxacillin and
      cloxacillin.

PMID- 4346509
TI  - The kinin system in allergic states.

PMID- 4346510
TI  - Primary aldosteronism due to hyperplasia of zona glomerulosa: failure of
      suppression by DOCA or stimulation by angiotensin.

PMID- 4346511
TI  - Fatal disseminated intravascular coagulation and hemolytic anemia following
      stibophen therapy: a study of basic mechanisms.

PMID- 4346512
TI  - [Antagonism of penicillin and levomycetin when used on pathogenic clostridia].

PMID- 4346513
TI  - [Effect of ristomycin and excess of orthophosphate in the medium on the growth of
      Proactinomyces fructiferi var. ristomycini. Formation of organic acids and
      biosynthesis of the antibiotic].

PMID- 4346514
TI  - The purification and properties of superoxide dismutase from Saccharomyces
      cerevisiae.

PMID- 4346515
TI  - A specific colorimetric and cytochemical substrate for ribonuclease T 2 :
      adenosine-3'-( -naphtylphosphate).

PMID- 4346516
TI  - Proteolytic enzymes in extracts of Schistosoma mansoni cercariae.

PMID- 4346517
TI  - Inhibitors of the pulmonary angiotensin I-converting enzyme.

PMID- 4346518
TI  - Anomalous kinetics observed in the catalysis of a peptide substrate with
      collagenase.

PMID- 4346520
TI  - Free radicals in malonic acid: a study of radical conformations at 77K and 295K
      by the ESR-technique.

PMID- 4346519
TI  - Behavior of cycloaldolase from Neurospora crassa towards substrate analogs and
      aldolase inhibitors.

PMID- 4346521
TI  - Synthesis and evaluation of the anticancer activity of some water soluble
      maleimide derivatives.

PMID- 4346523
TI  - Conformational isomers of nitrosyl-haemoglobin. An electron-spin-resonance study.

PMID- 4346522
TI  - The energy metabolism of human-blood polymorphonuclear cells. Action of various
      effectors, except hormones.

PMID- 4346524
TI  - [Cytomegalovirus and rubella virus infections during pregnancy].

PMID- 4346525
TI  - Variation of phosphorylase distribution in skeletal muscles.

PMID- 4346526
TI  - Histochemical study of TPPase and NDPase in the human nervous tissue, with
      particular reference to glia cells.

PMID- 4346527
TI  - Microbial and hepatic cuprein (superoxide dismutase). Isolation and
      characterisation of cuprein (superoxide dismutase) from Saccharomyces cerevisiae
      and bovine liver.

PMID- 4346528
TI  - Metabolism of pyridine nucleotides and its relation to DNA synthesis in
      regenerating mouse liver.

PMID- 4346529
TI  - [Studies on the composition of the lipoproteins in human lymph].

PMID- 4346530
TI  - Function of thiol groups in yeast pyruvate kinase.

PMID- 4346531
TI  - Disturbance by tumor promotors of epidermal growth control (chalone mechanism).

PMID- 4346532
TI  - Comparative thin-layer chromatography of indole-containing metabolites of
      tryptophan and their sulfur isosteres.

PMID- 4346533
TI  - Susceptibility and resistance to viral leukemogenesis in the mouse. IV.
      Mechanisms of host resistance to leukemia expression.

PMID- 4346534
TI  - Mechanism of syncytium formation between XC sarcoma cells and murine endocrine
      carcinoma cells.

PMID- 4346535
TI  - Rabbit kidney vacuolating virus in spontaneous Shope papillomas of cottontail
      rabbits.

PMID- 4346536
TI  - Tissue culture studies of mouse mammary tumor cells and associated viruses.

PMID- 4346537
TI  - Immunologic reactivity of the cat: immunosuppression in experimental feline
      leukemia.

PMID- 4346538
TI  - Virus-like particles in guinea pig oogonia and oocytes.

PMID- 4346539
TI  - Enhancement of tumor growth rate by interferon inducers.

PMID- 4346541
TI  - Transmission of lymphosarcoma from cattle to sheep.

PMID- 4346540
TI  - Precipitating antibody to an internal antigen of the C-type virus associated with
      bovine lymphosarcoma.

PMID- 4346542
TI  - [Susceptibility of various species of birds to the leukosis strains Mc-31, E-26
      and isolate Pts-56 and comparative pathomorphology of the induced changes].

PMID- 4346543
TI  - [Diagnosis of smallpox].

PMID- 4346544
TI  - [African zoonoses caused by viruses].

PMID- 4346545
TI  - [Symptomatology of the narcoleptic syndrome].

PMID- 4346546
TI  - Synthesis of glycogen in leucocytes from various precursors.

PMID- 4346547
TI  - Renal transplantation and viral infections. I. A retrospective serological study
      of renal transplantation recipients.

PMID- 4346548
TI  - Altered kinetic property of erythrocyte phosphoribosylpsyrophosphate synthetase
      in excessive purine production.

PMID- 4346549
TI  - [Study on the mechanism of action of glucose on excessive biosynthesis of
      porphyrins in rats].

PMID- 4346550
TI  - [Serum and cerebrospinal-fluid glutamic-oxaloacetic transaminase activity during
      neurological diseases].

PMID- 4346552
TI  - Quantitative data on the fine structural organization of the palisade zone of the
      median eminence.

PMID- 4346551
TI  - [5-Hydroxytryptophan and sleep in chronic schizophrenics].

PMID- 4346553
TI  - Fine structure of the autonomic nerves of the rabbit myometrium.

PMID- 4346554
TI  - [Histological studies on lymphatic organs in the chicken (Gallus domesticus) in
      the first year of age].

PMID- 4346555
TI  - [Electronmicroscopic studies on the embryonic and postembryonic genesis of the
      interstitial cells of the hen's ovary].

PMID- 4346556
TI  - A morphologic and histochemical study of biliary atresia in lamprey liver.

PMID- 4346558
TI  - Ultrastructure of the chick thymus.

PMID- 4346557
TI  - Corticotrophic cells in the rostral zone of the pars intermedia and in the
      adjacent neurohypophysis of the rat and mouse. An electron microscopic study.

PMID- 4346559
TI  - Secretory surface phenomena in freeze-etched preparations of the adenohypophysial
      cells and neurosecretory fibers.

PMID- 4346560
TI  - Histochemical demonstration of delta 5 -3  -OHD activity in the granulosa cells
      of ovarian follicles of immature and mature mice correlated with some
      ultrastructural observations.

PMID- 4346561
TI  - The effects of desiccation and starvation upon the weight, histology and
      ultrastructure of the reproductive tract of Biomphalaria glabrata, intermediate
      host of Schistosoma mansoni.

PMID- 4346562
TI  - Epithelial ultrastructure and the distribution of an estradiol sensitive antigen
      in the vagina of adult mice.

PMID- 4346563
TI  - [Fine structure of the protonephridial system of Turbanella cornuta Remane, a
      marine gastrotrich of the order Macrodasyoidea].

PMID- 4346564
TI  - [Metopirone test in menstruation disorders].

PMID- 4346565
TI  - Effects of pH on the intra- and extramitochondrial nicotinamide adenine
      dinucleotide systems.

PMID- 4346566
TI  - Landlord-supervised cooperative apartments: a new modality for community-based
      treatment.

PMID- 4346567
TI  - [Diagnostic use of sonar in pelvic pathology].

PMID- 4346568
TI  - Quantitative evaluation of normal and pathologic cerebral blood flow regulation
      to perfusion pressure. Changes in man.

PMID- 4346569
TI  - Acute optic neuropathy in older patients.

PMID- 4346571
TI  - The acid and alkaline phosphatases, inorganic pyrophosphatases and phosphoprotein
      phosphatase of bone. I. Characterization and assay.

PMID- 4346570
TI  - Studies on the mechanism of the antilipolytic effect of Paraoxon.

PMID- 4346573
TI  - Histone hydrolase activity of rat liver lysosomal cathepsin B2.

PMID- 4346572
TI  - The acid and alkaline phosphatases, inorganic pyrophosphatases and phosphoprotein
      phosphatase of bone. II. Distribution in subcellular fractions of bone tissue
      homogenates and structure-linked latency.

PMID- 4346574
TI  - The study of natural sleep after general anaesthesia in the cat.

PMID- 4346575
TI  - Effect of silica on phospholipids in the rat lung.

PMID- 4346576
TI  - Extensive superficial vulvectomy with primary skin grafting for premalignant
      lesions.

PMID- 4346577
TI  - Herpes hepatitis in adults.

PMID- 4346578
TI  - Efficacy of whooping-cough vaccines used in the United Kingdom before 1968.
AB  - The efficacy of pertussis vaccines was investigated in 33 areas in the United
      Kingdom from November 1966 until April 1968 inclusive. Bordetella pertussis was
      isolated from 1,293 persons, but there were only six isolations of B.
      papapertussis. Among vaccinated contacts under 5 years in homes in which B.
      pertussis was isolated 52% developed paroxysmal cough. The corresponding attack
      rate among unvaccinated contacts was 69%. These findings suggest that much of the
      pertussis vaccine in use for five or six years before 1968 was not very
      effective. However, vaccine from one producer was more effective than vaccine
      from another. Of the cultures of B. pertussis identified 89% were serotype 1, 3
      and only about 9% were serotype 1, 2, 3. Serotype 1, 2, 3 was isolated much more
      frequently from unvaccinated than from vaccinated children, but some cultures
      identified as type 1, 2, 3 were found on re-examination to contain colonies of
      type 1, 3. Virological investigations were made in some areas during the first
      year of the study. Of the wide variety of viruses identified adenovirus and
      parainfluenza virus were the most common groups. Virus isolation rates were
      similar in patients and symptomless contacts, but B. pertussis was isolated far
      more often from patients than from symptomless contacts. The evidence suggests
      that B. pertussis remained the major cause of whooping cough in the U.K.

PMID- 4346580
TI  - Technique of oil myelography.

PMID- 4346579
TI  - Comparison of corticotrophin and corticosteroid response to lysine vasopressin,
      insulin, and pyrogen in man.
AB  - Plasma corticotrophin (ACTH) and corticosteroid levels in response to lysine
      vasopressin (LVP), insulin hypoglycaemia, and pyrogen have been compared in seven
      subjects with normal pituitary adrenal function. Intramuscular vasopressin was a
      weak stimulus to corticotrophin release, peak values lying within the range 49 to
      141 pg/ml. Insulin hypoglycaemia consistently caused a more noticeable increase,
      with peak levels between 114 and 364 pg/ml, while pyrogen was the most powerful,
      corticotrophin levels rising to between 209 and 1,725 pg/ml. Peak plasma
      corticosteroid levels showed less pronounced differences between the three tests,
      and correlated poorly with peak ACTH levels. Thus, relatively small acute changes
      in corticotrophin levels produce near-maximal adrenal stimulation. Under these
      conditions, plasma corticosteroid measurements do not accurately reflect
      circulating corticotrophin levels. These findings help to explain the
      physiological basis of several observations on the corticosteroid responses to
      these clinical test procedures.

PMID- 4346581
TI  - Corticosteroid withdrawal in asthma.

PMID- 4346582
TI  - WHO collaborative studies on poliovirus type 3 strains isolated during the 1968
      poliomyelitis epidemic in Poland.
AB  - In 1968 in Poland an extensive outbreak of poliomyelitis, caused by type 3
      poliovirus, began about four months after small vaccine trials with the Leon
      12a(1)b (Sabin) and USOL-D bac vaccine strains had been carried out. Because of
      the temporal association, and because the first cases appeared in the province in
      which the USOL-D vaccine trial was carried out, a detailed investigation of the
      strains isolated from cases in the epidemic was made in four laboratories in an
      attempt to determine whether they were related to the two vaccine strains or to a
      "wild" strain. All the studies were made under code. The rct marker was of no
      help in determining the relationship of the epidemic strains to the vaccine
      strains. The McBride test and the elution marker test clearly separated the Leon
      12a(1)b strains from those from the cases, but were incapable of detecting
      whether the epidemic strains were related to the USOL-D bac strain or to wild
      type 3 strains. Thus the studies did not provide valid information on the origin
      of the epidemic.

PMID- 4346583
TI  - Role of vacuoles and vesicles in extracellular enzyme secretion from yeast.

PMID- 4346584
TI  - Studies on cell fusion and the rescue of SV40 from cell cultures of successive
      generations of C1 2  TSV 5  - and RHaT-produced hamster tumors.

PMID- 4346585
TI  - Studies on the immunogenicity of virus-infected lymphocytes for the production of
      antilymphocyte serum.

PMID- 4346586
TI  - [Anti-interferon activity of extracts of cells transformed by SV40 virus].

PMID- 4346587
TI  - Characterization of viomycin and its acyl derivatives.

PMID- 4346588
TI  - The total structure of viomycin by sequential analysis.

PMID- 4346589
TI  - Studies on steroid conjugates. X. Significance of conjugation involved in
      biosynthesis of 2-methoxyestrogen.

PMID- 4346590
TI  - A new phosphatase produced by Streptomyces yokosukanensis.

PMID- 4346591
TI  - Modifications in primate cerebral circulation and electrical activity with
      profound hypothermia.

PMID- 4346592
TI  - Cryoprotection of some rat heart enzymes.

PMID- 4346593
TI  - Enzymatic activities of the first two steps of liver HEME biosynthesis in
      experimental MHV-3 viral hepatitis.

PMID- 4346594
TI  - Alteration of properties of cell contacts during progression of hepatomas.

PMID- 4346595
TI  - Localization of erythrocyte membrane antigens by immune electron microscopy.

PMID- 4346596
TI  - Effect of dibutyryl cyclic AMP on the restoration of contact inhibition in tumor
      cells and its relationship to cell density and the cell cycle.

PMID- 4346597
TI  - Health care policy issues in the 1970s.

PMID- 4346599
TI  - Antibody response to a protein antigen (ovalbumin) in dissociated spleen cell
      cultures from primed mice. Evidence for a suppressive effect of antigen.

PMID- 4346600
TI  - Neuronal and glial enzyme studies in cell culture.

PMID- 4346598
TI  - Studies on the terminal stages of complement lysis.

PMID- 4346601
TI  - [Subacute action of low concentrations of chlorinated ethanes on rats with and
      without additional ethanol treatment. I. Biochemical and toxicometrical aspects,
      especially results in subacute and chronic toxicity studies with 1.1.2.2
      tetrachloroethane].

PMID- 4346602
TI  - Characteristics of "big ACTH" in human plasma and pituitary extracts.

PMID- 4346603
TI  - Cushing's disease with periodic hormonogenesis: one explanation for paradoxical
      response to dexamethasone.

PMID- 4346604
TI  - A radioimmunoassay for plasma aldosterone without chromatography.

PMID- 4346605
TI  - Normal peroxidase activity in Pendred's syndrome.

PMID- 4346606
TI  - Similarity of the estrogen receptor in human and rat mammary carcinoma.

PMID- 4346607
TI  - Immunochemical similarity between polysaccharide antigens of Escherichia coli 07:
      K1(L):NM and group B Neisseria meningitidis.

PMID- 4346608
TI  - [Survey on enterovirus infections in Matsue City, Shimane Prefecture (May 1969
      March 1971) with special reference to enterovirus isolation].

PMID- 4346609
TI  - [Neuroradiography in peripheral nerve lesions].

PMID- 4346610
TI  - Composition, structure and phase transition in yeast fatty acid auxotroph
      membranes: spin labels and freeze-fracture.

PMID- 4346611
TI  - Structure of the lipid phase of Rauscher murine leukemia virus.

PMID- 4346612
TI  - A spin label study of human erythrocyte carbonic anhydrases B and C.

PMID- 4346613
TI  - [Characteristics of the clinical picture, diagnosis and treatment of myasthenia
      in tumorous disease of the thymus gland].

PMID- 4346614
TI  - Treatment of metastatic trophoblastic disease: good and poor prognosis.

PMID- 4346615
TI  - Cell-mediated immunity in patients with ovarian carcinoma.

PMID- 4346616
TI  - Ultrasonic diagnosis of Wilms' tumors.

PMID- 4346617
TI  - Detection of feline syncytia-forming carrier state with a microimmunodiffusion
      test.

PMID- 4346618
TI  - The ultrastructural pathology of the rat epididymis after administration of  
      chlorhydrin (U-5897). I. Effects of a single high dose.

PMID- 4346619
TI  - [Choriocarcinoma in a male patient with circulating thyrotropic activity and
      adrenocortical hyperfunction].

PMID- 4346620
TI  - [Hypokalemic alkalosis with hyperplasia of the juxtaglomerular apparatus:
      Bartter's syndrome?].

PMID- 4346621
TI  - [Development and application of the radioimmunologic assay of plasma aldosterone
      and renin activity].

PMID- 4346622
TI  - [A case of transient gynecomasty with hyperestrogenesis of nontumoral testicular
      origin].

PMID- 4346623
TI  - [Effect of oral administration of L-Dopa on plasma TSH, ACTH and GH levels in
      normal subjects].

PMID- 4346624
TI  - [Microbiological analysis of dehydrated soups].

PMID- 4346626
TI  - Effects of irradiation on the survival of virus in West Coast oysters.
AB  - Gamma irradiation was evaluated as a means of inactivating poliovirus in shucked
      and whole shellfish. Results indicated that there was a significant survival of
      virus at all levels of radiation tested.

PMID- 4346625
TI  - Postmortem changes in surface preparations of the cochlea.

PMID- 4346628
TI  - Mutagenesis and enrichment of auxotrophs in Penicillium chrysogenum.
AB  - An efficient method for isolation of auxotrophs of Penicillium chyrysogenum
      involving mutagenesis with ethyl methanesulfonate followed by enrichment with
      sodium pentachlorophenate was developed. The auxotroph frequencies obtained were
      30 to 40%.

PMID- 4346629
TI  - Properties of DNA treated with S-(1,2-dichlorovinyl)-L-cysteine and a lyase.

PMID- 4346627
TI  - Thermal injury and recovery of Bacillus subtilis.
AB  - Exposure of Bacillus subtilis NCTC 8236 to sublethal temperatures produced a
      change in the sensitivity of the organism to salt and polymyxin. After 30 min at
      47 C, 90% of the population was unable to grow on a modified sulfite polymyxin
      sulfadiazine agar containing an added 1% NaCl, 1% glucose, and 1% asparagine. The
      data presented demonstrate that thermal injury results in degradation of both 16S
      and 23S ribonucleic acid (RNA) and in damage to the cell membrane, suggested by
      leakage into the heating mestruum of material absorbing at 260 nm. When the cells
      were placed in a recovery medium (Trypticase soy broth), complete recovery,
      indicated by a returned tolerance to salt and polymyxin, occurred within 2 hr.
      The presence of a protein inhibitor (chloramphenicol) and cell wall inhibitors
      (vancomycin and penicillin) during recovery had no effect, whereas the presence
      of an RNA inhibitor (actinomycin D) effectively inhibited recovery. Further data
      demonstrated that the injured cells were able to resynthesize both species of
      ribosomal RNA during recovery by using the fragments which resulted from the
      injury process. Also, precursor 16S and precursor 23S particles accumulated
      during recovery. The maturation of the precursor particles during recovery was
      not affected by the presence of chloramphenicol in the recovery medium.

PMID- 4346630
TI  - Studies on the substrate specificity of hexosaminidase A and B from liver.

PMID- 4346631
TI  - Studies of mitochondrial development prior to lactogenesis in the mouse mammary
      gland.

PMID- 4346632
TI  - Purification and properties of an endonuclease from Chlamydomonas.

PMID- 4346633
TI  - Studies on cell adhesion. II. Adhesion of cells to surfaces of diverse chemical
      composition and inhibition of adhesion by sulfhydryl binding reagents.

PMID- 4346634
TI  - The oxidation-reduction potentials and rates of oxidation of the cytochromes of
      Nitrobacter agilis.

PMID- 4346635
TI  - Electron paramagnetic resonance studies on nitrogenase. I. The properties of
      molybdoferredoxin and azoferredoxin.

PMID- 4346636
TI  - The covalent binding of D-fructose 1,6-diphosphate to muscle aldolase.

PMID- 4346637
TI  - Purification and properties of a cyclic nucleotide phosphodiesterase from bovine
      heart.

PMID- 4346638
TI  - Biogenesis of mitochondria: neuroendocrine effects on the development of
      respiratory functions in fat body mitochondria of the cockroach, Blaberus
      discoidalis.

PMID- 4346639
TI  - Electron microscopic study of reticulohistiocytoma. An unusual case of
      congenital, self-healing reticulohistiocytosis.

PMID- 4346640
TI  - Vitamin D metabolism. Recent advances.

PMID- 4346641
TI  - Acceleration of protein synthesis by angiotensin--correlation with angiotensin's
      effect on catecholamine biosynthesis.

PMID- 4346642
TI  - [Experimental results with the power-feedback system of an electrical hand
      prosthesis].

PMID- 4346643
TI  - Hepatoma and hepatitis-associated antigen.

PMID- 4346644
TI  - [Primary liver tumors in the angiographic picture].

PMID- 4346645
TI  - [Osteogenic sarcoma following irradiation].

PMID- 4346646
TI  - The effect of an oral contraceptive on serum lipids.

PMID- 4346647
TI  - Steroid contraceptives and plasma carotenoids.

PMID- 4346648
TI  - Keratohyalin granule-like mitochondrial inclusion in the neonatal rat tongue and
      esophageal epithelia.

PMID- 4346649
TI  - The linkage of genes for the human interferon-induced antiviral protein and
      indophenol oxidase-B traits to chromosome G-21.
AB  - 13 independent mouse-human somatic cell hybrid clones derived from beta
      propiolactone-inactivated Sendai stimulated cell fusion of human cells with mouse
      cells were tested for their sensitivities to human and mouse interferon. All of
      them were protected by mouse interferon and only six of the clones were protected
      by both human and mouse interferon. Only the six that were protected by human
      interferon were shown to express the human dimeric form of indophenol oxidase.
      Complete chromosomal analysis of the clones indicated human chromosome G-21 to be
      the only human chromosome in common for the six clones which had both phenotypes
      present. Nine subclones were derived from one of the clones expressing both
      phenotypes. Eight of the nine subclones were shown to retain both phenotypes,
      whereas one subclone lost both. Chromosomal analysis of the subclones indicated
      the loss of chromosome G-21 from the subclone which lost both phenotypes. It is
      apparent from these findings that the gene(s) for indophenol oxidase (IPO-B) and
      the gene(s) for the antiviral protein are syntenic and that they are linked to
      human chromosome G-21.

PMID- 4346651
TI  - The effects of various protecting agents on the inactivation of foot-and-mouth
      disease virus in aerosols and during freeze-drying.

PMID- 4346650
TI  - Intrinsic interference between different enveloped RNA viruses.

PMID- 4346652
TI  - Replication of vesicular stomatitis virus: the effect of purified interfering
      component.

PMID- 4346653
TI  - Electron microscopic studies on the development of infectious bovine
      rhinotracheitis virus in bovine kidney cells.

PMID- 4346654
TI  - Purification of mengovirus and identification of an A-rich segment in its
      ribonucleic acid.

PMID- 4346655
TI  - Reovirus type 3 encephalitis--a virologic and ultrastructural study.

PMID- 4346656
TI  - Subacute focal adenovirus encephalitis.

PMID- 4346657
TI  - Murine influenza virus encephalomyelitis. I. Neuropathological and
      immunofluorescence findings.

PMID- 4346658
TI  - Murine influenza virus encephalomyelitis. II. Electron microscopic observations.

PMID- 4346659
TI  - Granular cell tumors of the central nervous system.

PMID- 4346660
TI  - [Immunological determination of serum beta-lipoprotein].

PMID- 4346661
TI  - Control of renin secretion.

PMID- 4346662
TI  - The current state of immunity to polioviruses in New South Wales.

PMID- 4346663
TI  - [Splenotomography].

PMID- 4346664
TI  - Salivary gland disorders. II. Salivary tumors.

PMID- 4346665
TI  - Peripheral neuropathy with ethambutol.

PMID- 4346666
TI  - Maternal bronchial carcinoma and its possible relation to neonatal hypoglycaemia.

PMID- 4346667
TI  - Posterior fossa cisternography.

PMID- 4346668
TI  - The hypothalamo-hypophysial system in Acipenseridae. 3. The neurohypophysis of
      Acipenser guldenstadti Brandt and Acipenser stellatus Pallas.

PMID- 4346669
TI  - Ultrastructural observations on the pars descendens of the proximal tubule in the
      kidney of the male rat.

PMID- 4346670
TI  - The fine structure of the pancreatic nerves of the domestic fowl.

PMID- 4346671
TI  - Unique sensory endings in rat muscle spindles.

PMID- 4346672
TI  - The fine structure of the branchial heart appendage of the cephalopod Octopus
      dofleini martini.

PMID- 4346673
TI  - [Ultrastructural data on the myoepithelium: the pharynx of a bryozoan].

PMID- 4346674
TI  - The differentiation of foot-and-mouth disease virus subtypes by means of the
      passive immuno-hemolysis test.

PMID- 4346675
TI  - [Phase of resistance following non-specific stress or ACTH administration].

PMID- 4346676
TI  - Studies on mechanical actions of mepivacaine (Carbocaine) and its optically
      active isomers on isolated smooth muscle: role of Ca ++  and cyclic AMP.

PMID- 4346677
TI  - Hexoestrol analogues as probes of oestrogen receptors. I. Importance of hydrogen
      bonding groups for receptor binding.

PMID- 4346678
TI  - Hexoestrol analogues as probes of oestrogen receptors. II. Importance of hydrogen
      bonding groups for binding to uterine tissue and for uterotrophic activity.

PMID- 4346679
TI  - Ampicillin rash in children. Relationship to penicillin allergy and infectious
      mononucleosis.

PMID- 4346680
TI  - Inheritance of combined hyperlipoproteinemia: evidence for a new lipoprotein
      phenotype.

PMID- 4346681
TI  - Plasma testosterone stimulation-suppression dynamics in hirsute women.
      correlation with long-term therapy.

PMID- 4346682
TI  - Virilizing luteoma of pregnancy. Report of a case with measurements of
      testosterone and testosterone binding in plasma.

PMID- 4346683
TI  - Studies of platelet adhesiveness, glucose tolerance and serum liporotein patterns
      in patients with coronary artery disease.

PMID- 4346684
TI  - Arteriographic findings of focal nodular hyperplasia of the liver and review of
      the literature.

PMID- 4346686
TI  - [Immunological cross reaction between human breast cancer and mammopathy and
      virus-producing breast carcinomas of the mouse].

PMID- 4346685
TI  - Endoscopic pancreato-cholangiography. A preliminary report on technique and
      diagnostic significance.

PMID- 4346687
TI  - [Starvation and refeeding in the carp (Cyprinus carpio L). IV. Effect on
      polysomes in hepatocytes].

PMID- 4346688
TI  - Bacterial flora in the duodenum of patients after biliary fenestration.

PMID- 4346689
TI  - Chlorpromazine in malignant insulinoma.

PMID- 4346690
TI  - Tumor hypercalcemia.

PMID- 4346691
TI  - Association of ectopically produced hyperparathyroidism with hepatoma.

PMID- 4346692
TI  - Effects of caudate stimulation on unitary responses of the lateral geniculate
      body to light.

PMID- 4346693
TI  - Effect of tetanus toxin on the inhibitory neuromuscular junction of crayfish
      muscle.

PMID- 4346694
TI  - Myelin hypoplasia including peripheral neuropathy caused by three mutations of
      the mouse.

PMID- 4346695
TI  - Effects of guanidine derivatives on mitochondrial function. IV. Changes in citric
      acid cycle intermediates and NADH.

PMID- 4346696
TI  - Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture.
      IV. Nucleoside transport in cells depleted of nucleotides by treatment with KCN.

PMID- 4346697
TI  - The response of normal and polyoma virus-transformed BHK-21 cells to exogenous
      purines.

PMID- 4346698
TI  - Loss of density-dependent regulation of multiplication of BALB-3T3 cells
      chemically transformed in vitro.

PMID- 4346699
TI  - [Cohesion of particulate solids. II. Influence of particle size].

PMID- 4346700
TI  - Influence of acetylcholine on contractile force and cyclic nucleotide levels in
      the isolated perfused rat heart.

PMID- 4346701
TI  - Decreased contractility and norepinephrine content of guinea-pig seminal vesicles
      after chronic treatment with testosterone.

PMID- 4346702
TI  - The effects of tetanus toxin on neuromuscular transmission and on the morphology
      of motor end-plates in slow and fast skeletal muscle of the mouse.
AB  - 1. A sublethal dose of tetanus toxin was injected into the muscles of one hind
      leg of the mouse and caused local tetanus which persisted for 4 weeks.2.
      Neuromuscular transmission was studied in vitro in nerve-muscle preparations of
      soleus, a slow muscle, and extensor digitorum longus (EDL), a fast muscle, from 1
      day to 6 months after the injection of toxin.3. Soleus failed to respond to nerve
      stimulation, became supersensitive to acetylcholine and showed spontaneous
      fibrillations for several weeks before returning to normal. EDL did not show
      these changes. A higher dose of tetanus toxin, lethal within 24 hr, caused
      paralysis of EDL as well as soleus.4. In muscle fibres in which neuromuscular
      transmission was blocked spontaneous miniature end-plate potentials (m.e.p.p.s)
      were recorded. The frequency of m.e.p.p.s was increased by repetitive nerve
      stimulation but not by raising the external potassium concentration.5. The
      amplitude of spontaneous m.e.p.p.s showed a skew distribution because of a
      disproportionate number of potentials of less than 0.2 mV.6. Raising the external
      calcium concentration did not restore neuromuscular transmission.7. Histological
      examination of soleus showed atrophy of muscle fibres with normal preterminal
      axons. There was sprouting from motor nerve terminals and subsequently new motor
      end-plates were formed. These changes were not found in EDL.8. The results
      indicate that, in the mouse, tetanus toxin causes a presynaptic block of
      neuromuscular transmission and ;functional denervation' of muscle. Slow muscle is
      more sensitive to the effects of the toxin than fast.

PMID- 4346703
TI  - Delayed release of transmitter at the frog neuromuscular junction.
AB  - 1. After the end-plate potential (e.p.p.) there is an increase in the frequency
      of the miniature e.p.p.s. This delayed release of transmitter was studied at the
      frog neuromuscular junction, using conventional intracellular and extracellular
      recording techniques. E.p.p. amplitude was kept subthreshold by subnormal
      concentrations of activating divalent ions.2. The ratio delayed release: initial
      release had values between 2 and 140%, depending on the experimental conditions;
      it decreased with an increase in Ca concentration and quantal content.3. Delayed
      release is larger at low temperature than at room temperature.4. Delayed release
      is statistically independent of the amplitude of the preceding e.p.p.5. The time
      course of the decay of the delayed release is monotonic when strontium is the
      activating divalent ion; it shows a ;dip' in more than 50% of the cases when Ca
      activated release.6. The results were discussed in terms of the residual Ca ion
      hypothesis.

PMID- 4346704
TI  - Synaptic frequency response: the influence of sinusoidal changes in stimulation
      frequency on the amplitude of the end-plate potential.
AB  - 1. The synaptic response to frequency modulated trains of stimuli was
      investigated at the neuromuscular junction of the frog. The frequency of
      stimulation was usually varied sinusoidally about a carrier frequency of ca. 25
      impulses per sec (Hz).2. The post-synaptic response to sinusoidally modulated
      trains of nerve stimuli was found to grow almost linearly when the variations in
      input frequency were increased up to 60% of the carrier frequency.3. The synaptic
      frequency response (gain and phase) was reminiscent of that of a low-pass filter,
      best transmitting slow variations in input frequency.4. The synaptic filter
      characteristics could not be explained by the post-synaptic cable properties, but
      were attributed to presynaptic facilitation processes.

PMID- 4346705
TI  - [Treatment of metastatic lung cancer].

PMID- 4346706
TI  - [On changes in leukocyte oxidative enzymes in subjects exposed to prolonged
      action of cyanhydric acid in industrial environments].

PMID- 4346707
TI  - Treatment of anaerobic infections with lincomycin and clindamycin.

PMID- 4346708
TI  - Genetic manipulation of reovirus--a model for modification of disease.

PMID- 4346709
TI  - Release of amino-acids and neurosecretory substances after stimulation of nerve
      endings (synaptosomes) isolated from the hypothalamus.

PMID- 4346710
TI  - Tumours of the nervous system in mice treated neonatally with N-ethyl-N
      nitrosourea.

PMID- 4346711
TI  - [Regulation of cell function].

PMID- 4346712
TI  - Biosynthesis of aortic vascular graft tissue in the pig.

PMID- 4346713
TI  - [Reconstruction of the action potentials of the oculomotor nerve in the cat].

PMID- 4346714
TI  - [Polygraphic analysis of nocturnal sleep in children with essential enuresis].

PMID- 4346716
TI  - [On the postsynaptic control by thalamic and subthalamic structures of the
      bulbopontine and mesencephalic neurons].

PMID- 4346715
TI  - [Postsynaptic effects induced in bulbopontine and mesencephalic neurons by limbic
      system stimulation].

PMID- 4346717
TI  - [Jean Olmer (1094-1972)].

PMID- 4346718
TI  - [Drug addiction and the general hospital].

PMID- 4346719
TI  - [Pancreatitis in internal medicine].

PMID- 4346720
TI  - [Atrio-ventricular blocks as seen in an internal medicine department].

PMID- 4346721
TI  - [Transient spasmodic paraplegia as a manifestation of aortic medial necrosis].

PMID- 4346722
TI  - [Smallpox vaccination in Great Britain].

PMID- 4346723
TI  - [Complications caused by contaminated blood. Apropos of 2 cases with severe
      toxinic shock].

PMID- 4346724
TI  - [Crural paralysis during anticoagulant treatment].

PMID- 4346725
TI  - [Results of treatment of solid tumors with massive levels of methotrexate and
      folinic acid combination. Apropos of 49 cases].

PMID- 4346726
TI  - [Emergency selective angiography in severe hematemesis].

PMID- 4346727
TI  - [Diagnosis and therapy of endogenic hypercortisolism (Cushing's syndrome)].

PMID- 4346728
TI  - [Enzyme histochemical studies on the problem of invasive tumor growth].

PMID- 4346729
TI  - [Studies of islands of Langerhans in vitro. IV. Enzyme histochemical and
      biochemical studies of isolated islands of Langerhans in relation to survival
      time and glucose concentration].

PMID- 4346730
TI  - Some histochemical, biochemical and morphological observations relating to
      lipofuscin and mitochondria.

PMID- 4346731
TI  - Theophylline inhibits the transcription of the lac operon in Escherichia coli.

PMID- 4346732
TI  - Immunofluorescence studies on tissue cultures doubly infected with adeno and
      herpesviruses.

PMID- 4346734
TI  - [Biochemical control of blood serum in women following intensive androgenic
      therapy during the premenopausal period].

PMID- 4346733
TI  - [Chromatographic determination of polio antibodies in IgG and IgM fractions of
      the serum and comparison of results with the neutralization test].

PMID- 4346735
TI  - Calcium-membrane interactions in the myocardium: effects of ouabain, epinephrine
      and 3',5'-cyclic adenosine monophosphate.

PMID- 4346736
TI  - Hematologic complications of open heart surgery.

PMID- 4346737
TI  - Physician in Gilead.

PMID- 4346738
TI  - Syngeneic skin graft rejection associated with oncogenic viruses.

PMID- 4346739
TI  - Cerebral angiography and subtraction in neuro-otologic diagnosis.

PMID- 4346740
TI  - Pneumographic and isotopic procedures in neuro-otologic diagnosis.

PMID- 4346741
TI  - Bell's palsy.

PMID- 4346742
TI  - A review of viral infections of horses.

PMID- 4346743
TI  - General ligands in affinity chromatography. Cofactor-substrate elution of enzymes
      bound to the immobilized nucleotides adenosine 5'-monophosphate and nicotinamide
      adenine dinucleotide.
AB  - 1. Two different gels have been prepared suitable for the separation of a number
      of enzymes, in particular NAD(+)-dependent dehydrogenases, by affinity
      chromatography. For both the matrix used was Sepharose 4B. For preparation (a),
      NAD(+)-Sepharose, 6-aminohexanoic acid has been coupled to the gel by the
      cyanogen bromide method and then NAD(+) was attached by using dicyclohexylcarbodi
      imide; for preparation (b), AMP-Sepharose, N(6)-(6-aminohexyl)-AMP has been
      coupled directly to cyanogen bromide-activated gel. 2. Affinity columns of both
      gels retain only the two enzymes when a mixture of bovine serum albumin, lactate
      dehydrogenase and glyceraldehyde 3-phosphate dehydrogenase is applied. Subsequent
      elution with the cofactor NAD(+) yields glyceraldehyde 3-phosphate dehydrogenase
      whereas lactate dehydrogenase is eluted by applying the same molarity of the
      reduced cofactor. 3. The binding of both glyceraldehyde 3-phosphate dehydrogenase
      and lactate dehydrogenase to the gel tested, AMP-Sepharose, is strong enough to
      resist elution by gradients of KCl of up to at least 0.5m. A 0.0-0.15m gradient
      of the competitive inhibitor salicylate, however, elutes both enzymes efficiently
      and separately. 4. The elution efficiency of lactate dehydrogenase from AMP
      Sepharose has been examined by using a series of eluents under comparable
      conditions of concentration etc. The approximate relative efficiencies are: 0
      (lactate); 0 (lactate+semicarbazide); 0 (0.5mm-NAD(+)); 80 (lactate+NAD(+)); 95
      (lactate+semicarbazide+NAD(+)); 100 (0.5mm-NADH). 5. All contaminating lactate
      dehydrogenase activity can be removed from commercially available crude pyruvate
      kinase in a single-step procedure by using AMP-Sepharose.

PMID- 4346744
TI  - Intracellular localization of aldehyde dehydrogenase in rat liver.
AB  - 1. Distribution of aldehyde dehydrogenase activity in rat liver was studied by
      measuring the rate of disappearance of acetaldehyde in the presence of each of
      the subcellular fractions. These were obtained by rough separation of particulate
      fractions from the soluble portion of the cell, by differential centrifugation,
      and by isopycnic gradient centrifugation. 2. The maximal rate of acetaldehyde
      oxidation was 3.7 mumol/min per g, with an apparent K(m) value below 10(-5)m. The
      highest rate of activity was observed in phosphate buffers of high P(i)
      concentration (above 60mm). 3. The activity measured was completely dependent on
      NAD(+). 4. The microsomal fraction and the nuclei were inactive in the assay. Of
      the total activity 80% was found in the mitochondrial fraction and the remaining
      20% in the cytoplasm. 5. The distribution pattern is important from the point of
      view of acetaldehyde oxidation during ethanol metabolism. The apparent
      discrepancy of the results obtained by different workers and the localization of
      acetaldehyde oxidation in vivo is discussed.

PMID- 4346745
TI  - The expression of catechol oxidase activity during the hydroxylation of p
      coumaric acid by spinach-beet phenolase.
AB  - 1. The conditions under which oxygen consumption in excess of that required for
      the hydroxylation of p-coumaric acid to caffeic acid, catalysed by spinach-beet
      phenolase, can be suppressed, have been examined. 2. With
      dimethyltetrahydropteridine as electron donor, oxygen uptake was exactly
      equivalent to the caffeic acid produced, provided that p-coumaric acid was in
      excess, but with excess of reductant, oxygen uptake caused by the further
      oxidation of caffeic acid was also observed. 3. With equal concentrations of
      ascorbate and p-coumaric acid, equivalent oxygen uptake and caffeic acid
      production was found only in the first stages of the reaction, whereas with NADH
      substituted for ascorbate, oxygen uptake was in excess throughout. 4. When
      ascorbate was used, the period of the reaction over which this equivalence was
      found was decreased at high reaction rates and not observed at all with aged
      enzyme preparations; equivalence was restored by adding bovine serum albumin to
      these aged preparations. 5. Equivalence between oxygen consumption and caffeic
      acid production was observed with NADH, if small quantities of
      dimethyltetrahydropteridine were also added. 6. It is concluded that
      hydroxylation proceeds without the concomitant production of caffeic acid only if
      the enzyme is stabilized for hydroxylation by p-coumaric acid and the reductant,
      and is protected from attack by o-quinones.

PMID- 4346746
TI  - Lipid composition of membranes of amine-storage organelles.
AB  - 1. The lipid composition of the membranes from isolated 5-hydroxytryptamine
      storage organelles of blood platelets of rabbits and of those from chromaffin
      granules of bovine adrenal medulla was compared. 2. In contrast with the
      membranes of the chromaffin granules, those of the 5-hydroxytryptamine organelles
      did not contain lysophosphatidylcholine (lysolecithin). 3. Both the
      cholesterol/phospholipid ratio and the relative proportions of
      phosphatidylethanolamine (kephalin), phosphatidylinositol and phosphatidylserine
      were about the same in both membranes, whereas phosphatidylcholine (lecithin) and
      sphingomyelin showed somewhat higher values in the membranes of the 5
      hydroxytryptamine organelles. 4. In conclusion, the release of 5
      hydroxytryptamine from blood platelets is probably not correlated with the
      presence of lysophosphatidylcholine in the membranes of the storage organelles
      and may thus differ from the mechanism of catecholamine release in adrenal
      medulla.

PMID- 4346747
TI  - N 6 -(  2 -isopentenyl) adenosine: biosynthesis in vitro in transfer RNA by an
      enzyme purified from Escherichia coli.

PMID- 4346748
TI  - Carbohydrate content and glycogenolytic acitivity in human placenta and fetal
      heart and lung.

PMID- 4346749
TI  - First cleavage division of the mouse zygot. An ultrastructural study.

PMID- 4346750
TI  - Evolution of the apical body in golden hamster spermatids with some reference to
      primates.

PMID- 4346751
TI  - [Arteriography of malignant retroperitoneal tumors in children].

PMID- 4346752
TI  - Immunological control of polyoma virus oncogenesis in mice.
AB  - Adult CBA mice thymectomized, treated with antilymphocytic globulin (ALG) and
      inoculated with human leprosy organisms were accidentally infected with polyoma
      virus and all developed tumours. After cessation of ALG administration, some
      animals were given spleen cells from syngeneic donors immunized with polyoma
      virus; none developed tumours. Similar results were obtained in mice deliberately
      infected with polyoma virus but not with leprosy organisms. Passive transfer of
      antibody before but not after virus inoculation prevented tumour formation in
      immunosuppressed recipients. Virus infection in thymectomized, lethally
      irradiated and bone marrow reconstituted mice resulted in only a very low
      incidence of tumours. These results emphasize the role of immunological
      surveillance in preventing polyoma tumour formation under natural conditions.

PMID- 4346754
TI  - Effect of alloxan diabetes, insulin & diabetogenic hormones on intestinal
      transport of tyrosine in rats.

PMID- 4346753
TI  - Isolation of arginine acceptor-proteins from normal rat liver and Novikoff
      hepatoma supernatant.
AB  - In the present report a procedure for the isolation of more specific arginine
      receptors from the soluble fraction of rat liver and Novikoff hepatoma is
      described. In normal rat liver the specific activity of these receptors from the
      soluble fraction of rat liver and Novikoff hepatoma is described. In normal rat
      liver the specific activity of these receptors is fifteen times greater than that
      of the other proteins whereas in the Novikoff it is only three to four times
      higher. Attempts to sub-fractionate this class of acceptors would seem to
      indicate a relative homogeneity.

PMID- 4346755
TI  - Identification and typing of clostridia in raw milk in Egypt.

PMID- 4346757
TI  - Atypical sarcoma of the iliotibial band.

PMID- 4346756
TI  - New culture conditions for Clostirdium histolyticum leading to production of
      collagenase of high specific activity.

PMID- 4346758
TI  - The value of plasma testosterone estimation in the diagnosis of virilizing
      ovarian neoplasia.

PMID- 4346759
TI  - A stucy on the effect of aldosterone on the extramitochondrial adenine nucleotide
      system in rat kidney.

PMID- 4346760
TI  - Glucocorticoid and mineralocorticoid receptors for aldosterone.

PMID- 4346761
TI  - Conversion of cystitis glandularis to adenocarcinoma.

PMID- 4346763
TI  - The cytology of urine of pediatric cancer patients.

PMID- 4346762
TI  - Evaluation of the Sellers-Schmidt-ball rapid antibiotic susceptibility test.

PMID- 4346764
TI  - [Abnormalities of sodium and water metabolism with special reference to
      hypertensive diseases].

PMID- 4346765
TI  - [Melanin thesaurismosis with special reference to melanocyte stimulating hormone
      (MSH) secretion anomalies].

PMID- 4346766
TI  - [Pseudohypoparathyroidism].

PMID- 4346767
TI  - [Primary hepatocellular carcinoma with polycythemia, hypercholesterenia and
      various other clinical symptoms].

PMID- 4346768
TI  - [Histopathological and histoenzymological aspects of chronic enteropathies of
      different etiologies].

PMID- 4346770
TI  - Characterisation of derepressed mutants of an F-like R factor.

PMID- 4346769
TI  - A colicin-tolerant mutant of Escherichia coli with reduced levels of cyclic AMP
      and a strong bias towards lambda lysogeny.

PMID- 4346771
TI  - [From antigen-antibody combination to the effector cell reaction. Transmission of
      information].

PMID- 4346772
TI  - Thirst and the limbic system.

PMID- 4346773
TI  - Melkersson's syndrome.

PMID- 4346774
TI  - Immunological aspects of Hodgkin's disease.

PMID- 4346776
TI  - [Effects of brain-stem stimulation on seizure discharges of neo-, archi- and
      paleocortex with special reference to the subthalamus].

PMID- 4346775
TI  - The cancer cell.

PMID- 4346777
TI  - [Coarctation of the abdominal aorta].

PMID- 4346779
TI  - [Limitations and indications of intravenous urography in renal failure].

PMID- 4346778
TI  - [Hematologic disorders in acute alcoholism. Study of 27 chronic alcoholic
      patients hospitalized in a state of intoxication].

PMID- 4346780
TI  - [Pressor effect of angiotensin II and norepinephrine in patients with
      hypertension treated with alpha methyldopa].

PMID- 4346782
TI  - [Orthophosphoric acid monoester phosphohydrolase activity of the repressible
      inorganic pyrophosphate phosphohydrolase I from Candida utilis].

PMID- 4346781
TI  - [Variability of physiological properties in the genus Microsporum Gruby. I.
      Utilization of Oleum pedum tauri by M. audouinii and M. gypseum].

PMID- 4346783
TI  - [Determination of plasma cortisol levels in children treated with ACTH during
      Still's disease and rheumatoid arthritis].

PMID- 4346786
TI  - [Multiple brain tumors of various germinative line].

PMID- 4346785
TI  - Ultrastructure of the nerves and sense receptors of Polystomoides renschi Rohde
      and P. malayi Rohde (Monogenea: Polystomatidae).

PMID- 4346784
TI  - [Subpellicular microtubules in the meroxoites of Eimeria falciformis (Coccidia,
      Sporozoa)].

PMID- 4346787
TI  - The quantitative dermination of quartz in coal dust by infrared spectroscopy.

PMID- 4346788
TI  - Toxicity of a substituted hydrazine for turkeys.

PMID- 4346789
TI  - Morphological changes in livers of rats fed polychlorinated biphenyls: light
      microscopy and ultrastructure.

PMID- 4346790
TI  - [Pulmonary complications following lymphographies with lipiodol].

PMID- 4346791
TI  - [Cytophysiologic study of adenohypophyseal changes in the tench treated with
      metopirone].

PMID- 4346793
TI  - [Macronuclear and micronuclear ultrastructures in Tracheloraphis dogieli, a
      marine ciliate with diploid macronuclei].

PMID- 4346792
TI  - [Intramitochondrial bacteria and pecularities of cytostomopharyngeal
      ultrastructure in the ciliate, Urotricha ovata Kahl (Ciliata)].

PMID- 4346794
TI  - [Study of the latencies between pontogeniculo-occipital activities in the pons of
      lateral geniculate nuclei and external rectus muscles in cats].

PMID- 4346796
TI  - Studies on the wholesomeness of ready-to-eat meat products. I. Bacteriological
      evaluation of comminuted heated products.
AB  - Bacteriological studies were conducted on comminuted heated types of ready-to-eat
      meat products. Seventy-five per cent of the samples showed total counts in the
      range of 100-10,000 organisms per gm. Of potential food poisoning organisms,
      coagulase positive staphylococci were present in 4% and Clostridium perfringens
      in 1.7% of all samples in low numbers. Of indicator organisms for fecal and
      sewage contamination, Escherichia coli were found in 3.2% and Streptococcus
      fecalis in 5.4% of the samples. The heat treatment applied during processing is
      not sufficient to destroy these organisms.

PMID- 4346795
TI  - [Direct radioimmunochemical determination of plasmatic renin activity].

PMID- 4346797
TI  - Stimulation of adrenal ornithine decarboxylase by adrenocorticotropin and growth
      hormone.

PMID- 4346798
TI  - Effect of polyphloretin phosphate on the induction of thyroid hormone secretion
      by various thyroid stimulators.

PMID- 4346799
TI  - A model for the evaluation of estrogens: withdrawal bleeding in ovariectomized
      rhesus monkeys.

PMID- 4346800
TI  - Studies of the levels and synthesis of cytochrome c during adult development of
      the blowfly Lucilia cuprina.

PMID- 4346801
TI  - Phosphofructokinase activity in skeletal muscle extracts following administration
      of epinephrine.

PMID- 4346802
TI  - Fish liver fructose 1,6-diphosphatase. I. Purification of the enzyme from
      Genypterus chilensis and studies on adenosine 5'-monophosphate inhibition.

PMID- 4346803
TI  - Properties of modified cytochromes. I. Equilibrium and kinetics of the pH
      dependent transition in carboxymethylated horse heart cytochrome c.

PMID- 4346804
TI  - Preparation of the heme protein P-450 from the adrenal cortex and some of its
      properties.

PMID- 4346805
TI  - Glycoproteins and blood group activity. I. Oligosaccharides of serologically
      inactive hog submaxillary glycoproteins.

PMID- 4346806
TI  - Cyclic adenosine 3',5'-monophosphate-dependent protein kinase of human
      erythrocyte membranes.

PMID- 4346807
TI  - Calcium-mediated interactions between the antidiuretic hormone and renal plasma
      membranes.

PMID- 4346808
TI  - Inactivation of hormone-sensitive lipase in extracts of adipose tissue.

PMID- 4346809
TI  - Catalysis of  -iminoglutarate formation from  -ketoglutarate and ammonia by
      bovine glutamate dehydrogenase.

PMID- 4346810
TI  - Transport of succinate in Escherichia coli. I. Biochemical and genetic studies of
      transport in whole cells.

PMID- 4346811
TI  - Protein synthesis in single cell suspensions from rat liver. I. General
      properties of the system and permeability of the cells for leucine and
      methionine.

PMID- 4346812
TI  - ACTH-induced alterations in catecholamine metabolism in man.

PMID- 4346813
TI  - A kindred with familial glucocorticoid suppressible aldosteronism.

PMID- 4346814
TI  - Dissociation of MSH and ACTH release in man.

PMID- 4346815
TI  - Steroid determination from complex mixtures by high pressure chromatographic
      techniques.

PMID- 4346816
TI  - Clinical use of radioimmunological plasma insulin assessment.

PMID- 4346818
TI  - [Double hepatic scintigraphy (gold-selenomethionine) in the diagnosis of primary
      tumors of the liver].

PMID- 4346817
TI  - [Penicillamine effect on the hydroxylation of proline and lysine].

PMID- 4346819
TI  - Apicoectomy as an adjunct to diagnosis.

PMID- 4346820
TI  - [Electrophysiological exploration of the blink reflex in facial paralysis].

PMID- 4346821
TI  - [Effect of erythrocytes on kininase activity in the blood].

PMID- 4346822
TI  - [Mechanism of induction of immunity to virus infections: interruption of
      intercellular virus multiplication].

PMID- 4346823
TI  - [EB virus: a study of nucleic acids].

PMID- 4346824
TI  - Cholera: new aids in treatment and prevention.

PMID- 4346825
TI  - Adenosine 3',5'-monophosphate in pancreatic islets: glucose-induced insulin
      release.
AB  - Glucose-induced release of insulin from perifused rat islets is associated with
      elevated islet adenosine 3',5'-monophosphate. If values for adenosine 3',5'
      monophosphate are compared to insulin release during theophylline or glucose
      stimulation and theophylline plus glucose stimulation, it suggests a minor role
      for adenosine 3',5'-monophosphate in directly stimulating insulin release but a
      prominent role in modulating glucose-induced release of insulin.

PMID- 4346826
TI  - Noradrenergic stimulation of cyclic adenosine monophosphate in rat Purkinje
      neurons: an immunocytochemical study.
AB  - A specific immunofluorescent histochemical method for cyclic adenosine
      monophosphate was used to study rat cerebellum. After topical treatment with
      norepinephrine or stimulation of norepinephrine-containing afferents from locus
      coeruleus, there was a striking increase in the number of Purkinje cells with
      strong cyclic adenosine monophosphate reactivity. Other putative inhibitory
      transmitters had no significant effect on staining of Purkinje cells. The results
      provide the first histochemical support for the hypothesis that cyclic adenosine
      monophosphate can be generated postsynaptically in central neurons in response to
      noradrenergic stimuli.

PMID- 4346827
TI  - [Kinetic study of blood cortisol during coma: changes in the circadian rhythm].

PMID- 4346828
TI  - [Incidence and clinical aspects of coronary accidents related to digestive
      surgery].

PMID- 4346829
TI  - [Cardiac stimulation technics in the treatment of tachycardia].

PMID- 4346831
TI  - [Application of crossed circulation to the treatment of acute hepatic failure of
      viral origin].

PMID- 4346830
TI  - [Rapidly regressive electrocardiographic aspects of antero-septal necrosis].

PMID- 4346832
TI  - [Changes in respiratory mechanics during prolonged artificial ventilation].

PMID- 4346833
TI  - [Influence of tracheotomy or intubation cannulas on ventilatory work].

PMID- 4346834
TI  - [Inappropriate hypersecretion of antidiuretic hormones (ISADH). Apropos of a case
      observed during late acute intermittent porphyria in an adult].

PMID- 4346835
TI  - [Pseudotumoral tuberculosis of the liver. Apropos of a personal case].

PMID- 4346836
TI  - [A rare etiology of serofibrinous pleurisy: periodic disease. Apropos of a case].

PMID- 4346837
TI  - [Treatment of heart failure in general medical practice. Principles to follow.
      Errors to avoid].

PMID- 4346838
TI  - [Acute intermittent porphyria associated with Biermer's anemia. Value of the
      glycocoll test].

PMID- 4346839
TI  - [Psychism and somatization in hemorrhagic rectocolitis. Retrospective value of
      graphology].

PMID- 4346840
TI  - [Determination of gentamicin in the cerebrospinal fluid (CSF) after lumbar
      injections. Results observed in 22 adult patients and children. Therapeutic
      implications].

PMID- 4346841
TI  - [Mechanism of renal compensation in diabetes mellitus. 3. Exploration of the
      mechanism of dilution and concentration].

PMID- 4346842
TI  - [Mechanism of renal compensation in diabetes mellitus. IV. Some unusual aspects
      of blood sugar-glycosuria, diuresis-glycosuria relationships].

PMID- 4346843
TI  - [Hyperosmolar coma revealing diabetes in an adult with type II Albright's
      syndrome].

PMID- 4346844
TI  - Nonuniformity of sympathetic nerve activity to the skin and kidney.

PMID- 4346845
TI  - Intracellular Cl concentrations and influxes across the brush border of rabbit
      ileum.

PMID- 4346846
TI  - Interrelationship of cyclic AMP, lipolysis, and respiration in brown fat cells.

PMID- 4346847
TI  - Ouabain-sensitive component of brown fat thermogenesis.

PMID- 4346848
TI  - Intrarenal secretion of renin in the dog: effect of furosemide.

PMID- 4346849
TI  - Malignant giant cell tumor of the tendon sheath. Ultrastructural study and review
      of the literature.

PMID- 4346850
TI  - Myoepithelioma of the palate. Histochemical and ultrastructural observations.

PMID- 4346851
TI  - Gallbladder bacteriology, histology, and gallstones. Study of unselected
      cholecystectomy specimens in Honolulu.

PMID- 4346852
TI  - Biochemical variability in the skin.

PMID- 4346853
TI  - Acceleration of catecholamine biosynthesis in sympathetically innervated tissues
      by angiotensin-II-amide..
AB  - 1. The effect of angiotensin-II-amide on the biosynthesis of catecholamines (CA)
      has been studied in a number of isolated tissues in vitro.2. Angiotensin
      increased the synthesis of CA from (14)C-tyrosine in guinea-pig atria and portal
      vein, in rat vasa deferentia and the rabbit portal vein.3. Angiotensin had no
      effect on synthesis of CA from (14)C-labelled DL-DOPA.4. The conditions required
      to demonstrate an increased synthesis were critical with respect to incubation
      time and angiotensin concentration. Effects were most readily apparent after
      incubation for 1 h with concentrations of angiotensin ranging from 10(-9) to 10(
      7)M. Higher concentrations caused a significant reduction in synthesis.5. An
      increased release of newly synthesized CA into the incubation medium was
      sometimes seen in the presence of angiotensin. However, there was no correlation
      between increased synthesis and release of CA.6. Angiotensin was rapidly
      destroyed when incubated with guinea-pig or rat tissues in Krebs solution. The
      increase in CA synthesis was only apparent at a time when the incubation medium
      could have contained only a fraction of the original angiotensin activity.7. It
      is concluded that the effect of angiotensin is not due to increased release of
      noradrenaline (NA) or to inhibition of NA uptake into nerves. It is possible that
      angiotensin may influence the activity of tyrosine hydroxylase or its cofactors
      by an as yet unknown mechanism.

PMID- 4346854
TI  - A myotoxin secreted by some piscivorous Conus species.
AB  - 1. Toxins isolated from the venom apparatus of Conus magus and Conus achatinus
      have the same pharmacological properties, but differ from the toxins of several
      other piscivorous species of cone shells.2. C. magus and C. achatinus toxins are
      heat labile at pH 8.5. A single lethal component with an approximate molecular
      weight of 10,000 was isolated from C. achatinus toxin by exclusion
      chromatography.3. Animals died from a characteristic spastic paralysis after
      intravenous injection of the toxin.4. Nerve transmission was unaffected by the
      toxin; skeletal muscle appeared to be the primary site of action. The toxin
      caused a persistent contracture of rat diaphragm muscle, and a dose-dependent
      decline in twitch tension. The contracture was potentiated by caffeine.5. The
      decline in twitch tension was associated with depolarization of the cell
      membrane. Action potential height and the maximum rate of rise declined, and
      spike propagation failed when the resting potential had declined to approximately
      60 mV. The muscle recovered very slowly on washout of the toxin. The
      depolarization could be reversed by exposure of the preparation to 5 mM Na(+)
      solution or tetrodotoxin or saxitoxin.6. Miniature end-plate potential frequency
      in the rat diaphragm decreased, as did the quantal content of the end-plate
      potential. The acetylcholine-induced contraction and depolarization of the
      chronically denervated rat diaphragm were increased by low doses of toxin and
      reduced by higher, depolarizing toxin doses. The K(+)-induced contraction and
      depolarization of innervated diaphragm were similarly affected by the toxin.7.
      Cardiac and smooth muscle were relatively resistant to the toxin. The isotonic
      contraction of the isolated perfused guinea-pig heart was increased by the toxins
      from both Conidae. The heart rate decreased. Guinea-pig atrial cells showed a
      small decrease in action potential height and maximum rate of rise. Rabbit sino
      atrial cells showed increases in action potential height, maximum diastolic
      potential and maximum rate of rise of the spike at low toxin levels, and no
      change in any of these parameters at high levels. There was a decrease in the
      rate of the spontaneously beating atrium. Atrioventricular nodal potentials
      showed no change other than a slight increase in the maximum rate of rise of the
      action potential.8. It is postulated that the action of the toxin may be related
      to a change in the Ca(++) permeability of the excitable membrane, which makes it
      unstable, leading to a secondary, depolarizing entry of Na(+). The effects of the
      toxin are compared with those of batrachotoxin, which it somewhat resembles.

PMID- 4346855
TI  - New virus infections.

PMID- 4346856
TI  - Interferon studies with Japanese and U.S. rubella virus strains.
AB  - Japanese strains of rubella virus have been claimed not to be teratogenic, and
      tests on three Japanese strains showed that they induced high levels of
      interferon in human placental cell cultures obtained from conceptuses ranging
      from 13 to 24 weeks' gestational age, whereas two strains derived from the U.S.A.
      induced low levels. Both Japanese and U.S. strains induced similar but low levels
      in fetal lung cell cultures and leucocyte preparations. A representative Japanese
      strain and a U.S. strain were both interferon-sensitive. If indeed a strain can
      be shown to be non-teratogenic it could lead to an alternative, safer rubella
      vaccine.

PMID- 4346857
TI  - Whooping cough.

PMID- 4346858
TI  - Radiotherapy and carcinoma of the parotid.

PMID- 4346859
TI  - [Relationship of clinical picture, serological examination and finding of
      cytomegalovirus in the urine].

PMID- 4346860
TI  - [Respiratory viruses in acute diseases of the lower respiratory tract of
      hospitalized children up to the age of 6 years].

PMID- 4346861
TI  - [Microbiological studies on herpesvirus infections in the upper respiratory tract
      of the horse].

PMID- 4346862
TI  - [Endocrine regulation of labor in cattle, sheep and goats].

PMID- 4346863
TI  - Relation between steroidogenesis and 3',5'-cyclic AMP production in isolated
      adrenal cells.

PMID- 4346864
TI  - Simultaneous determinations of plasma ACTH and GH levels after an oral
      metyrapone.

PMID- 4346865
TI  - Results of a clinical trial with intermittent doses of adriamycin in lung cancer.

PMID- 4346866
TI  - Spontaneous immunity to mammary-tumour virus (MTV)-associated antigens in mice
      and its influence on syngeneic mammary-tumour growth.

PMID- 4346869
TI  - Ultrastructure of primary human liver cell carcinoma using material already
      blocked in paraffin.

PMID- 4346868
TI  - Some investigations concerning the growth characteristics of Entamoeba
      histolytica in monoxenic association in a new culture medium.

PMID- 4346867
TI  - Electronic coupling between neurons in the rat lateral vestibular nucleus.

PMID- 4346870
TI  - The effect of malnutrition on human central nervous system myelin.

PMID- 4346872
TI  - Differentiation of carcinomatous and bacterial meningitis.

PMID- 4346871
TI  - Intramedullary spinal cord metastases. Clinical and radiographic findings in nine
      cases.

PMID- 4346874
TI  - What's your diagnosis? Granular cell myoblastoma.

PMID- 4346873
TI  - Subacute necrotizing encephalomyelopathy with vacuolated cells in the bone
      marrow.

PMID- 4346875
TI  - Nonlinear response of the reticuloendothelial system upon stimulation.

PMID- 4346876
TI  - [A rapid plaque assay for parainfluenza viruses types 2 and 3].

PMID- 4346877
TI  - The effect of premature weaning on the response of rat adrenals to stress and
      ACTH.

PMID- 4346878
TI  - [Sarcoma of peripheral nerves--neurosarcoma].

PMID- 4346879
TI  - Alteration of the relative stability of dA-dT and dG-dC base pairs in DNA.
AB  - Several small alkylammonium ions can eliminate, or even reverse, the usual
      dependence of the DNA transition temperature on base composition. For example, in
      3 M tetramethylammonium chloride, or 2.4 M tetraethylammonium chloride, DNAs of
      different base compositions all melt at a common temperature, and with a greatly
      decreased breadth of transition reflecting only the sequence-independent
      components of melting cooperativity. At still higher concentrations of such
      additives, dG.dC-rich DNAs melt at lower temperatures than dA.dT-rich molecules.
      Circular dichroism spectra show that these additives alter the structure of the
      DNA double helix very little at room temperature. This differential (base
      specific) effect on helix stability is investigated with several small additives
      related to the tetraalkylammonium ions. Additives larger than tetraethylammonium
      ion have little differential effect on helix stability. Preferential binding of
      ions to dA.dT base pairs, requiring fit into a "groove" of DNA, is consistent
      with these data and with equilibrium binding studies. These differential effects
      can be distinguished from general destabilizing effects, which are independent of
      specific features of macromolecular conformation or chemistry. Possible
      experimental uses of this ability to alter the base-composition-dependent
      components of the stability of the DNA helix are discussed, as well as the
      insight this phenomenon provides into the molecular basis for the differential
      stability of dA.dT and dG.dC base pairs.

PMID- 4346880
TI  - Fructose 1,6-bisphosphatase: the role of lysosomal enzymes in the modification of
      catalytic and structural properties.
AB  - Seasonal variations in the properties of rabbit-liver fructose 1,6-bisphosphatase
      have now been linked to corresponding changes in the levels of proteolytic
      activity in the liver extracts. Incubation of native fructose 1,6-bisphosphatase
      with purified liver lysosomes causes a 3-fold increase in catalytic activity at
      pH 9.2, with a smaller, and variable, decrease in activity tested at pH 7.5.
      These changes in catalytic properties are accompanied by the appearance of a
      smaller subunit, as was previously reported for the enzyme treated with
      subtilisin. AMP, a negative modulator of fructose bisphosphatase activity,
      protects against this action of lysosomes. This proteolytic modification of
      fructose bisphosphatase by lysosomal enzymes may play a role in the modulation of
      gluconeogenesis.

PMID- 4346881
TI  - Identification of the synthesis of guanosine tetraphosphate (MS I) as insertion
      of a pyrophosphoryl group into the 3'-position in guanosine 5'-diphosphate.
AB  - The phosphate transfer system of Haseltine et al., consisting of a ribosomal wash
      obtained from a stringent strain of Escherichia coli, washed ribosomes, GTP, and
      ATP, was used to prepare large quantities of guanosine tetra- and
      pentaphosphates, the magic spot compounds MS I and MS II of Cashel and Gallant.
      In our hands, the Haseltine et al. system yielded predominantly guanosine
      tetraphosphate, ppGpp. This system was used exclusively in the described
      experiments, with ATP labeled with (32)P in the beta- and gamma-positions as
      donor. The beta-label was found to produce a ppG[unk]p and the gamma-label a ppGp
      0001000 1101011 0011100 0011100 1101011 0001000 0000000 0101100 1110010 0100001
      0100001 0100001 0110010 0101100 0100000 0100000 1110000 . Furthermore, [(3)H]GDP
      + [gamma-(32)P]ATP yielded ppGpp in a (3)H:(32)P ratio of 1:1. The results
      indicate a transfer of the terminal pyrophosphoryl group of ATP as a unit. The
      position of the transferred pyrophosphoryl was assayed for by preparation of pG
      from ppGp with Zn(++)-activated inorganic pyrophosphatase from yeast. The pG was
      then assayed with 3'-nucleotidase, which liberated practically all the labeled
      phosphate. This result indicate that the phosphate transfer from ATP to GDP
      yields guanosine 5'-diphosphate-3'-diphosphate.

PMID- 4346882
TI  - Appearance in trypsinized normal cells of reactivity with antibody presumably
      specific for malignant cells.
AB  - Trypsinization of normal human diploid cells (WI-38 and MRC 5) resulted in the
      appearance of complement-fixing reactivity with an immunoglobulin (anti-HeLa G
      globulin), prepared against a purified HeLa (malignant human) cell antigen (G),
      which reacts with various malignant human cell lines and tumors but not with
      certain normal human cells. The presence of receptors in the nonreacting,
      untrypsinized normal human cells and the specificity of the reactive groups that
      appeared after trypsinization was established by the fact that the antibody could
      be completely absorbed with large quantities of packed, untrypsinized human cells
      but not with similar quantities of either rabbit or guinea-pig kidney tissue
      culture cells, which did not react with this antibody either before or after
      treatment with trypsin. The change produced by trypsinization is thus similar to
      the previously demonstrated appearance of reactive groups with the same anti-HeLa
      G globulin in normal human cells at certain times after infection with herpes
      simplex and vaccinia viruses. The fact that the trypsinized WI-38 cells absorbed
      more antibody than the same number of cells before trypsinization indicated that
      trypsinization resulted not only in the appearance of reactivity with antibody
      but also in a greater concentration of combining receptors, which is unlike the
      situation with lectins producing agglutinability without an increase in the
      number of receptors. Moreover, the fact that absorption with trypsinized normal
      cells removed larger amounts not only of the antibody reacting with the trypsin
      treated WI-38 cells but also of antibody that reacts with WI-38 cells infected
      with herpes simplex virus and with the malignant HEp-2 cells, suggests that the
      combining groups that emerge after trypsinization of the normal human cells are
      the same or similar to those present in malignant human cells (HEp 2) and to
      those that emerge after infection of the normal human cells with herpes simplex
      virus.

PMID- 4346883
TI  - In vitro repression of the transcription of gas operon by purified gal repressor.
AB  - We have studied the in vitro repression of gal mRNA synthesis by the gal
      repressor from Escherichia coli. By use of a four-step purification procedure
      involving chromatography on phosphocellulose, DEAE-cellulose, and an affinity
      resin, the gal repressor has been purified about 1600-fold from a crude cell
      extract. The purification was aided by use of a cell extract made after prophage
      induction of cells lysogenic for bacteriophage lambda that carries the gal
      repressor gene (galR). The highly purified gal repressor is an effective and
      specific repressor of in vitro synthesis of gal mRNA with lambda gal DNA as
      template. Both D-fucose and D-galactose overcome the action of gal repressor; the
      half-maximal concentrations of D-fucose and D-galactose for overcoming the action
      of repressor are 1 mM and 0.5 mM, respectively. The repressor fails to repress
      gal-specific transcription when the gal DNA contains a cis-dominant operator
      constitutive (O(c)) mutation. We conclude that the gal repressor recognizes the
      gal operator site and acts by preventing gal transcription.

PMID- 4346884
TI  - Surface changes in temperature-sensitive Simian virus 40-transformed cells.
AB  - A binding assay that shows consistent differences in the amounts of tritium
      labeled concanavalin A that bind to normal and virally transformed cells was used
      to study the kinetic changes of cell surface in SV40-transformed 3T3 cells that
      express the transformed phenotype in a temperature-sensitive manner (tsSV3T3
      cells). The increase in concanavalin A binding, which paralleled the appearance
      of the characteristics of transformed cells, was dependent on the synthesis of
      cellular DNA. In agreement with the results of binding studies, exponentially
      growing tsSV3T3 cells agglutinated at much lower lectin titers (concanavalin A as
      well as wheat-germ agglutinin) at 32 degrees than at 39 degrees .

PMID- 4346885
TI  - Secretion and extracellular processing of procollagen by cultured human
      fibroblasts.
AB  - Cultures of human diploid fibroblasts were labeled with radioactive proline and
      glycine, and the precursor of collagen (procollagen) in cells and medium was
      characterized by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. A
      covalently assembled molecule with the composition (pro alpha1)(2).pro alpha2
      (approximate molecular weight, 360,000) appeared intracellularly soon after
      synthesis of the constituent chains, and could be detected in the medium after 60
      min of labeling. The molecule was stabilized by disulfide bonds between cysteine
      residues in the amino-terminal procollagen peptide sequences of the three chains.
      Collagenase digested the molecule to peptides of 30,000 molecular weight or less.
      Limited digestion with pepsin excised nonhelical procollagen peptides, yielding
      native, triple-helical tropocollagen. Pulse-chase experiments indicated that a
      peptidase in the medium sequentially excised the nonhelical peptides from the
      molecule, generating tropocollagen molecules that aggregated as fibers in the
      cell layer. The excised, nonhelical procollagen peptides contained little or no
      proline or glycine. Intramolecular bonds of the lysyl aldehyde type were not
      detected in the secreted molecule, as reduction of the medium always resulted in
      quantitative recovery of free pro alpha chains in dodecyl sulfate-urea. Lysyl
      derived, covalent bonds appeared to form between tropocollagen molecules
      aggregating in the cell layer. We suggest the term "pro-tropocollagen" for the
      assembled, secreted precursor of collagen.

PMID- 4346886
TI  - Effect of environmental pH on rescue of Simian virus 40.
AB  - Rescue of SV40 virus after Sendai virus-mediated fusion of transformed mouse or
      hamster cell lines with permissive monkey cells was strikingly dependent on pH in
      the range 6.4-8.8, with a maximum at pH 8.4. The titer of virus recovered at pH
      8.4 was 2 logs higher than that at pH 7.6, and 4 logs higher than that at pH 6.4.
      The pH-sensitive step was neither the number of heterokaryocytes formed, which
      was essentially the same at pH 7.6 and 8.4, nor the degree of SV40 replication in
      the monkey cells, which was also unaffected by pH variation in the range 7.2-8.4.

PMID- 4346888
TI  - Expression of differentiated functions in hepatoma cell hybrids: alanine
      aminotransferase.
AB  - The expression of alanine aminotransferase (EC 2.6.1.2), an enzyme that is
      inducible in the liver, has been examined in somatic hybrid cells formed by
      crossing well-differentiated rat hepatoma cells with rat diploid epithelial
      cells, the former characterized by high activity and inducibility of the enzyme,
      and the latter by the absence of detectable activity. The hybrid cells that
      contain essentially complete chromosomal sets of the two parents show only very
      low activity and little inducibility. Among numerous "segregated" hybrid
      subclones, which have lost up to 40% of the chromosomes initially present,
      several show expression of intermediate levels of enzyme activity and very little
      inducibility, and two independent subclones are characterized by full re
      expression of both baseline and inducible enzyme activity. The electrophoretic
      mobility of the enzyme from the latter hybrids, from the hepatoma parental cells,
      and from rat liver is identical. The absence of a correlation between total
      chromosome number of the hybrid cells and re-expression of alanine
      aminotransferase suggests that the loss of specific chromosomes is required for
      re-expression. In these hybrid cells, the re-expression of alanine
      aminotransferase baseline and inducibility is independent of that of tyrosine
      aminotransferase inducibility.

PMID- 4346887
TI  - Phosphorylation of ribosomal proteins by substrate-specific protein kinases from
      rabbit reticulocytes.
AB  - Three protein kinase activities have been identified in ribosome-free supernatant
      from rabbit reticulocytes by DEAE-chromatography. Two of the protein kinase
      activities have similar substrate specificities, but differ in respect to
      dependency on cAMP for activation. These kinases preferentially phosphorylate
      histone, and also phosphorylate identical ribosomal proteins. One protein band in
      the 40S ribosomal subunit and six protein bands in the 60S subunit are
      phosphorylated, as demonstrated by Na dodecyl sulfate-polyacrylamide gel
      electrophoresis and autoradiography. The third kinase activity preferentially
      phosphorylates casein, instead of histone, and can use both [gamma-(32)P]ATP and
      [gamma-(32)P]GTP as phosphate donors. This protein kinase activity phosphorylates
      one protein band in the 40S subunit different from that phosphorylated by the
      other two kinases and four bands in the 60S subunit, only one of which is
      coincident with the proteins phosphorylated by the histone-specific activities.

PMID- 4346889
TI  - RNA-linked short DNA fragments during polyoma replication.
AB  - During in vitro incubation, nuclei from polyoma-infected cells elongate the
      daughter strands of the replicative intermediate of polyoma DNA. This process is
      now shown to involve the transient formation of short fragments (4-5 S), a
      process that is stimulated by the addition of ribonucleoside triphosphates. The
      presence of stretches of RNA at the 5'-end of short DNA chains was determined
      from Cs(2)SO(4) equilibrium centrifugation and from the finding that isotope from
      alpha-(32)P-labeled deoxynucleoside triphosphates was recovered in 2'(3')
      ribonucleotides after alkaline hydrolysis. Transfer occurred preferentially with
      [alpha-(32)P]dCTP as substrate. Starvation for deoxynucleotides by in vivo
      treatment with hydroxyurea resulted in the accumulation of short fragments that
      are deficient in RNA. Our results suggest that a late step during the
      discontinuous synthesis of polyoma DNA is selectively inhibited when
      deoxynucleotides are in short supply.

PMID- 4346890
TI  - Adenosine 3':5'-cyclic monophosphate as a regulator of bacterial transformation.
AB  - Adenosine 3':5'-cyclic monophosphate added to exponentially growing cells of
      Hemophilus influenzae strain Rd increases competence for transformation 100- to
      10,000-fold. Cyclic AMP added to near-stationary or stationary cells does not
      increase competence over the high level normally found in the early stationary
      phase.

PMID- 4346891
TI  - Solvent proton magnetic relaxation dispersion in solutions of concanavalin A.
AB  - Concanavalin A, a protein isolated from jack beans, exhibits several important
      biological properties, all of which are related to its ability to bind and
      precipitate specific polysaccharides. Concanavalin A is a dimer at pH 5.6, and
      has one transition-metal and one calcium-ion binding site per monomer unit of
      molecular weight 27,000. Both metal-ion sites must be occupied for the protein to
      be active. It is of interest to determine the role of the transition metal ion in
      Concanavalin A and its relationship to the sugar binding activity of the protein.
      We report the magnetic field and temperature dependences of the spin-lattice
      magnetic relaxation rates of solvent protons in aqueous solutions of zinc and
      manganese derivatives of Concanavalin A, and the influence of monosaccharide
      binding on these rates. The results of a leastsquares fit of the data to the
      theory, with five adjustable parameters, indicate that there is one rapidly
      exchanging water molecule ligand on the Mn(2+) ion, with a residence lifetime of
      2.5 musec at 25 degrees , and with its protons 0.27 nm (2.7 A) from the Mn(2+)
      ion. We find that at low magnetic fields (proton Larmor frequencies below about
      10 MHz), the correlation time for the dipolar interaction between the Mn(2+)
      electronic spin moment and the protons on the water ligand is the spin-lattice
      relaxation time tau(S) of the Mn(2+) moment, but that at higher magnetic fields
      the correlation time for the dipolar interaction is determined by the Brownian
      rotational tumbling of the protein, because of the substantial variation of
      tau(S) with magnetic field. Monosaccharide binding to manganese Concanavalin A
      has little effect on the relaxation rates of solvent protons, a result that
      indicates that the sugars do not bind directly to the transition metal in the
      protein.

PMID- 4346892
TI  - Evidence for boundary lipid in membranes.
AB  - Cytochrome oxidase (EC 1.9.3.1) isolated from beef-heart mitochondria with an
      appropriate phospholipid content forms vesicular structures. Lipid-protein
      interactions in this model membrane system were studied with the lipid spin
      label, 16-doxylstearic acid. As the phospholipid/protein ratio is varied, two
      spectral components are observed. At low phospholipid/protein ratios (</=0.19 mg
      of phospholipid per mg of protein) the lipid spin label is highly immobilized. At
      higher phospholipid content an additional component characteristic of fluid lipid
      bilayers is evident. By summation of digitalized spectra and subsequent
      integration it was shown that all composite spectra could be approximated by
      assuming only two components are present, and that the amount of phospholipid
      bound to the protein is independent of the extent of the fluid bilayer region.
      The experimentally determined amount of phospholipid for maximum occupancy of
      protein-bound sites is about 0.2 mg of phospholipid per 1.0 mg of protein.
      Calculations show that this ratio is consistent with a single layer of
      phospholipid surrounding the protein complex. The data are interpreted as
      evidence for a boundary of immobilized lipid between the hydrophobic protein and
      adjacent fluid bilayer regions in this membrane model system.

PMID- 4346894
TI  - Mechanism of interferon uptake in parental and somatic monkey-mouse hybrid cells.
AB  - Dose-response curves of interferons in different sensitive cells are regularly
      sigmoidal. In somatic monkey-mouse hybrid cells, however, a significant decrease
      in the slope of the curve for primate interferon was observed, while the dose
      response effect was unaltered for mouse interferon. High concentrations of
      primate interferon were 10- to 100-times less effective in hybrid clones than in
      parental monkey CV-1 cells; at low concentrations the antiviral effect was 10- to
      20-times higher in hybrid clones than in the parental cells. The receptor(s) for
      primate interferon located on the cell membrane was destroyed by trypsin but not
      by EDTA. Similarly, acid pH inactivated these receptor sites. We, thus, postulate
      that the antiviral effect is, at least partially, related to the amount of
      interferon taken up by the cells. Uptake could be conditioned by active
      cooperation of two cell-specific factors: a receptor and an activator. The
      activator might be missing or inactivated for primate interferon in the hybrid
      cells. We suggest that the putative antiviral protein is not cell-species
      specific, and that information for its synthesis in the hybrid cells might be
      located on a mouse rather than a monkey chromosome.

PMID- 4346895
TI  - [Spontaneous rupture of the esophagus].

PMID- 4346893
TI  - Terminal deoxynucleotidyl transferase in a case of childhood acute lymphoblastic
      leukemia.
AB  - Cells from a patient with childhood acute lymphoblastic leukemia contain an
      apparent DNA polymerase activity that was not found in any other cells except
      thymus cells. The enzyme has the properties of terminal transferase, an enzyme
      known to be found in thymocytes. The cells also contain the three major DNA
      polymerases found in growing cells. The results suggest that these tumor cells
      arose from a block in the differentiation of thymocytes. Terminal transferase may
      be a marker for the origin of leukemic cells.

PMID- 4346896
TI  - [Chronic esophageal stenosis caused by foreign body].

PMID- 4346897
TI  - [Cancer of the esophagus successfully treated by cobalt therapy. Esophago-gastric
      resection for stenosis].

PMID- 4346898
TI  - [Pseudo-cardio-fundal cancer of vascular nature].

PMID- 4346899
TI  - [Compression of the fundus of the stomach by a bronchogenic cyst].

PMID- 4346900
TI  - [2 myoid tumors of the stomach of exogastric development].

PMID- 4346901
TI  - [False image of tumor of the duodenal bulb caused by compression of the retracted
      gallbladder following perforated and occluded pyloric ulcer].

PMID- 4346902
TI  - [Late complete stenosis of the 3d portion of the duodenum of congenital origin in
      an 8-year-old boy].

PMID- 4346903
TI  - [Intestinal obstruction caused by a coprolith originating in a Meckel's
      diverticulum].

PMID- 4346904
TI  - [Primary lithiasis of the small intestine and intestinal tuberculosis].

PMID- 4346905
TI  - [Celio-mesenteric thrombosis].

PMID- 4346907
TI  - [Chronic amebic colitis].

PMID- 4346906
TI  - [2 lacunar aspects of the cecum].

PMID- 4346908
TI  - Reactive stenotic segmental colitis cranial to a colonic cancer.

PMID- 4346909
TI  - [Vaterian ampulloma. Cure exceeding 10 years after limited excision].

PMID- 4346910
TI  - [Endocrine tumor of the pancreas with carcinoid syndrome].

PMID- 4346911
TI  - [Hepatoma of the left liver].

PMID- 4346912
TI  - [Acute pancreatitis with arteriovenous fistula].

PMID- 4346913
TI  - What's new in surgery. Gynecology and obstetrics.

PMID- 4346914
TI  - Debridement of dermal ulcers with collagenase.

PMID- 4346915
TI  - The effect of isomers of DDD on the ACTH-induced steroid output, histology and
      ultrastructure of the dog adrenal cortex.

PMID- 4346916
TI  - Studies on the mechanism of cystamine prevention of several liver structural and
      biochemical alterations caused by carbon tetrachloride.

PMID- 4346917
TI  - [Cerebrospinal fluid findings in the meningeal rejection reaction following
      myelography].

PMID- 4346918
TI  - Influence of gonadotrophins and cyclic AMP on carbohydrate and protein metabolism
      in the immature rat ovary.

PMID- 4346919
TI  - On the action of tolbutamide in normal man. 3. Interaction of tolbutamide with
      glucagon, aminophylline and arginine in stimulating insulin response.

PMID- 4346920
TI  - Synthesis and biological activity of some 2' derivatives of adenosine 3',5'
      cyclic phosphate.

PMID- 4346921
TI  - Band pattern of the segment-long-spacing form of collagen. Its use in the
      analysis of primary structure.

PMID- 4346922
TI  - Histidine at the active site of superoxide dismutase.

PMID- 4346923
TI  - Alkyl isocyanates as active-site-specific reagents for serine proteases. Reaction
      properties.

PMID- 4346924
TI  - Comparison of catalytic units of muscle and liver adenosine 3',5'-monophosphate
      dependent protein kinases.

PMID- 4346925
TI  - Comparative kinetic study of human pyruvate kinases isolated from adult and fetal
      livers and from hepatoma.

PMID- 4346926
TI  - Periodate oxidation and amino-catalyzed elimination of the terminal nucleoside
      from adenylate or ribonucleic acid. Products of overoxidation.

PMID- 4346927
TI  - Glycosyltransferase and sialic acid levels of normal and transformed cells.

PMID- 4346928
TI  - Chemical synthesis of  -L-fucopyranosyl phosphate and  -L-rhamnopyranosyl
      phosphate.

PMID- 4346929
TI  - [Adrenocortical hormones and arteriosclerosis].

PMID- 4346930
TI  - A meal of pig.

PMID- 4346931
TI  - A- and C-type particles of mouse myeloma cells.

PMID- 4346932
TI  - Influence of hormones, poly I:C, polyvinylpyrrolidon and  -stimulators on in
      vitro infection with murine leukemia virus.

PMID- 4346933
TI  - Nearest neighbor frequencies of mitochondrial DNA in spontaneous mouse hepatomas.

PMID- 4346935
TI  - Resistance to methylene dimethane sulphonate (MDMS) in L1210 cells in vitro.

PMID- 4346934
TI  - Tumours of the peripheral and central nervous system induced in BD-rats by
      prenatal application of methyl methanesulfonate.

PMID- 4346936
TI  - [The effect of glucocorticoids and ACTH on the excitability of the hypothalamus
      and limbic formations of the dog brain].

PMID- 4346937
TI  - [The mechanism of blockade and recovery of neuromuscular transmission under the
      influence of armin in experiments on cats].

PMID- 4346938
TI  - [The effect of thiouracil and perchlorate on the relationships between
      iodoprotein fractions in the thyroid gland].

PMID- 4346939
TI  - Plasmaphoresis and plasma exchange in the treatment of hyperlipaemia and
      xanthomatous neuropathy in patients with primary biliary cirrhosis.
AB  - Two patients with primary biliary cirrhosis who were increasingly incapacitated
      by xanthomatous neuropathy are described. Treatment with a low fat diet and
      cholestyramine was unhelpful but repeated plasmaphoresis by simple venesection in
      one and plasma exchange using an IBM blood cell separator in the other over a
      period of several months completely relieved the symptoms of the neuropathy,
      caused skin xanthomata to recede, and lowered plasma lipid levels in both
      patients. There was no evidence that this procedure was associated with any
      deleterious effects on the liver. The size of the cholesterol pool in xanthomata
      in one patient was estimated to be approximately 35 g, and from the plasma
      cholesterol response to plasmaphoresis at varying frequency it was suggested that
      the excess of cholesterol synthesis over degradation was less than 0.3 g/day in
      one patient and less than 0.4 g/day in the other. On the basis of the response in
      these patients it is suggested that the turnover rates of lipid pools are
      relatively slow in biliary cirrhosis and that cholesterol accumulation is more
      likely to be due to a reduced catabolic rate than to an increased synthetic rate
      of cholesterol. Plasmaphoresis or plasma exchange are useful methods of treatment
      for the rare patient afflicted by this resistant and distressing complication of
      biliary cirrhosis.

PMID- 4346940
TI  - Health administration offers many opportunities.

PMID- 4346941
TI  - Federal health services grants.

PMID- 4346942
TI  - [Ultrastructural localization of glucose-6-phosphatase in the rat adrenal
      cortex].

PMID- 4346943
TI  - Arrhenoblastoma in a 12-year-old girl.

PMID- 4346944
TI  - Carcinoma of the breast with cartilaginous metaplasia.

PMID- 4346945
TI  - Adenine nucleotide mediation of fructolysis and motility in bovine epididymal
      spermatozoa.

PMID- 4346946
TI  - Affinity column purification of protocollagen proline hydroxylase from chick
      embryos and further characterization of the enzyme.

PMID- 4346947
TI  - Basic amino acid transport in Escherichia coli. II. Purification and properties
      of an arginine-specific binding protein.

PMID- 4346949
TI  - Characterization of the interaction of a protein inhibitor with adenosine 3',5'
      monophosphate-dependent protein kinases. II. Mechanism of action with the
      holoenzyme.

PMID- 4346948
TI  - Hormonal modulation of amino acid transport in rat hepatoma cells in tissue
      culture.

PMID- 4346950
TI  - Electron spin resonance studies with dioldehydrase. Evidence for radical
      intermediates in reactions catalyzed by coenzyme B 12.

PMID- 4346951
TI  - Separate phosphodiesterases for the hydrolysis of cyclic adenosine 3',5'
      monophosphate and cyclic guanosine 3',5'-monophosphate in rat liver.

PMID- 4346952
TI  - Cytochrome c oxidase from bakers' yeast. I. Isolation and properties.

PMID- 4346953
TI  - Cytochrome c oxidase from bakers' yeast. II. Site of translation of the protein
      components.

PMID- 4346954
TI  - Isolation of a protein component of sodium-potassium transport adenosine
      triphosphatase containing ligand-protected sulfhydryl groups.

PMID- 4346955
TI  - Erythrocyte protein phosphorylation.

PMID- 4346956
TI  - Association of glyceraldehyde 3-phosphate dehydrogenase with the human
      erythrocyte membrane. Effect of detergents, trypsin, and adenosine triphosphate.

PMID- 4346957
TI  - A comparison of the responses of mitochondrial and cytosol histidine-pyruvate
      aminotransferases to nutritional and hormonal treatments.

PMID- 4346959
TI  - The intermediate in the uridine diphosphate galactose 4-epimerase reaction.
      Resolution of an apparent ambiguity.

PMID- 4346958
TI  - Localization of the polyadenylate sequences in messenger ribonucleic acid and in
      the heterogeneous nuclear ribonucleic acid of HeLa cells.

PMID- 4346960
TI  - Cyclic adenosine 3',5'-monophosphate-stimulated protein kinase and a substrate
      associated with cardiac sarcoplasmic reticulum.

PMID- 4346961
TI  - Treatment of fractures of the radius and ulna with compression plates.

PMID- 4346962
TI  - Resolution of dansyl leucine and dansyl isoleucine.

PMID- 4346963
TI  - Cytochemistry of polymorphonuclear neutrophils in schistosomiasis.

PMID- 4346964
TI  - Diagnosis of extrahepatic biliary obstruction in infants by immunochemical
      detection of LP-X and modified  131 I-Rose Bengal excretion test.

PMID- 4346965
TI  - [Studies on the membrane-bound enzyme activities and their localization in toad
      skeletal muscle].

PMID- 4346966
TI  - Properties of strains of Escherichia coli K12 carrying mutant lex-1 and uvrA6
      alleles.

PMID- 4346967
TI  - Hemobilia.

PMID- 4346968
TI  - [Secondary structure of ACTH].

PMID- 4346969
TI  - Isolated adrenal cortex cells: hypersensitivity to adrenocorticotropic hormone
      after hypophysectomy.
AB  - Cells from the adrenals of hypophysectomized rats (up to 28 days after operation)
      require less adrenocorticotropic hormone to induce one-half maximal rate of
      production of 3',5'-adenosine monophosphate than do cells from the adrenals of
      intact rats. A corresponding increase in sensitivity is reflected in the
      steroidogenic response to adrenocorticotropic hormone up to 2 days after
      hypophysectomy.

PMID- 4346971
TI  - Adrenal zona glomerulosa after hypophysectomy in the Mongolian gerbil.

PMID- 4346970
TI  - Ultrastructure of the outer epithelium of the mantle in the clam Mercenaria
      mercenaria in relation to calcification of the shell.

PMID- 4346972
TI  - [Sociohygienic contribution to the organization of dispensary care of hepatitis
      in school children].

PMID- 4346973
TI  - Dipyrone for treatment of post-operative pain.

PMID- 4346974
TI  - Significance of Staphylococcus epidermidis in the clinical laboratory.
AB  - Susceptibility to 11 antibiotics was determined for 63 cultures of Staphylococcus
      aureus and 63 cultures of Staphylococcus epidermidis obtained at random from the
      clinical laboratory. The incidence of resistance to nine of these antibiotics was
      greater for S. epidermidis than for S. aureus. Studies of the minimal inhibitory
      concentration of these cultures to clindamycin showed that 61 cultures of S.
      aureus were susceptible whereas only 46 cultures of S. epidermidis were
      susceptible to this antibiotic. Although cultures of S. aureus were more active
      in the production of seven virulence factors, some cultures of S. epidermidis
      produced virulence factors. By successive cultivation in increasing
      concentrations of clindamycin, resistant variants were obtained for 10 cultures
      of S. aureus and 3 cultures of S. epidermidis. The presence of subinhibitory
      concentrations of clindamycin inhibited the production of some virulence factors
      by the resistant variants. In view of the greater resistance of S. epidermidis to
      antibiotics and its ability to produce virulence factors, its isolation in the
      clinical laboratory should not be regarded lightly.

PMID- 4346975
TI  - Value of desiccated swabs for streptococcal epidemiology in the field.
AB  - Streptococcal surveys in foreign countries or remote areas may be greatly
      enhanced by the use of calcium alginate swabs desiccated in sterile silica gel.
      Delays of up to 4 weeks before return to a base laboratory are feasible, and the
      need for fresh media or laboratory facilities in the field may be eliminated.
      Comparison of direct plating on crystal violet blood agar versus delayed silica
      gel preservation during surveys in Uganda, Haiti, Colombia, and Miami, Fla.,
      showed no significant loss of positive cultures from skin lesions and suggests
      that desiccated swabs increase the recovery of bacitracin-sensitive Streptococcus
      pyogenes (presumptive group A) from throats.

PMID- 4346976
TI  - Three-day assay for human cytomegalovirus applicable to serum neutralization
      tests.
AB  - A fluorescing cell assay (FCA) technique utilizing the indirect fluorescent
      antibody method to measure human cytomegalovirus (CMV)-infected cells has been
      applied to the rapid determination of CMV-neutralizing antibody. Human sera with
      complement fixation titers to CMV of 1/32 or greater and fluorescein-conjugated
      rabbit anti-human globulin are the primary and secondary reagents in the
      fluorescent-antibody test. FCA measured in 3 days the same number of infectious
      units measured by plaque assay in 2 weeks. FCA and plaque assay yielded identical
      neutralizing antibody titers to CMV in 20 human sera.

PMID- 4346977
TI  - Identification of Vibrio cholerae by pyrolysis gas-liquid chromatography.
AB  - Cholera-like vibrios examined by pyrolysis gas-liquid chromatography could be
      distinguished from other common aerobic gram-negative bacilli, including oxidase
      positive organisms, e.g., Aeromonas. Vibrios in Heiberg group I were subdivided
      into three types on the basis of differences in one complex in the chromatogram,
      and these closely corresponded with the identification as classical, El Tor, or
      "intermediate" biotypes of Vibrio cholerae by conventional methods.

PMID- 4346978
TI  - Microbiological testing of Skylab foods.
AB  - The Skylab manned space flight program presented unique food microbiology
      problems. This challenge was successfully met by careful evaluation of the total
      Skylab food system by considering the nature of Skylab foods, their processing
      and handling, and Skylab food safety requirements. Some of the unique problems
      encountered with the Skylab foods involved: extended storage times, variations in
      storage temperatures, no opportunity to resupply or charge foods after launch of
      the Skylab Workshop, first use of frozen foods in space, first use of a food
      warming device in weightlessness, relatively small size of production lots
      requiring statistically valid sampling plans, and use of the food as an
      accurately controlled segment of sophisticated life science experiments.
      Consideration of all of these situations generated the need for definitive
      microbiological tests and test limits. These tests are described in this paper
      along with the rationale for their selection. Test results are reported which
      show successful compliance with the test limits.

PMID- 4346980
TI  - Serum neutralization tests with infectious bovine rhinotracheitis-infectious
      pustular vulvovaginitis (IBR-IPV) virus.

PMID- 4346979
TI  - [Effect of radio-opaque substances and local anesthetics on ciliary motility of
      the rhino-pharyngo-esophageal mucosa of the frog].

PMID- 4346981
TI  - Characteristics of a paramyxovirus isolated from an aborted bovine fetus.

PMID- 4346982
TI  - Japanese encephalitis in horses in Japan.

PMID- 4346983
TI  - Effects of fasting and diet on enzyme profiles in ovine liver and adipose tissue.

PMID- 4346984
TI  - Adrenal response to ACTH in the pig.

PMID- 4346985
TI  - Effects of "soluble silica" on growth, nutrient balance and reproductive
      performance of albino rats.

PMID- 4346986
TI  - Prenatal development, histochemistry and innervation of porcine muscle.

PMID- 4346987
TI  - Innervation of genetically enlarged muscles from double-muscled cattle.

PMID- 4346988
TI  - The pharmacology and ionic dependency of amino acid responses in the frog spinal
      cord.
AB  - 1. The isolated frog spinal cord was used to study the action of amino acids and
      their antagonists on primary afferent terminals and motoneurones. The direct
      effects of these substances were observed by bathing the cord in 20 mM magnesium
      sulphate (thus blocking synaptic transmission) and recording the polarization
      level of the dorsal and ventral roots.2. gamma-Aminobutyric acid (GABA) and
      glutamic acid depolarized the dorsal root and reduced dorsal-root potentials,
      while glycine produced only weak and variable effects. Glutamic acid also
      depolarized the ventral root; GABA usually produced either a hyperpolarization or
      had little effect, while glycine caused variable effects.3. Bicuculline and
      picrotoxin antagonized all the synaptic potentials recorded on the dorsal root,
      as well as the GABA responses on both dorsal and ventral roots.4. All the
      synaptic potentials examined remained and were markedly prolonged in the absence
      of external chloride except the ventral root-dorsal root potential. Replacement
      of the physiologic complement of chloride during chloride-free perfusion restored
      the potentials to their original time courses.5. Depolarizing amino acid
      responses remained in the absence of external chloride, while hyperpolarizing
      responses were reversed into depolarizations. Return to normal Ringer solution re
      established the hyperpolarizations.6. Removal of external sodium reversibly
      abolished the amino acid depolarizations but had little effect on the
      depolarizations in response to applications of high external potassium
      concentrations.7. The results support the hypotheses (a) that GABA mediates
      presynaptic inhibition by depolarizing primary afferent terminals and (b) that
      the GABA-mediated depolarization is sodium dependent.8. The results also indicate
      that GABA utilizes different ionic mechanisms to mediate presynaptic inhibition
      (sodium) and post-synaptic inhibition (chloride) in the amphibian (and presumably
      in the mammal).

PMID- 4346989
TI  - Neuromuscular transmission in a mammalian preparation in the absence of blocking
      drugs and the effect of D-tubocurarine.
AB  - 1. Neuromuscular transmission in the presence and absence of D-tubocurarine was
      examined in cut muscle preparations of the rat diaphragm using intracellular
      recording techniques. The method of localizing the end-plates is described and
      evidence is presented indicating that end-plate potential (e.p.p.) recordings
      were made close to the end-plate region and that reliable estimates of the
      quantum content of e.p.p.s could be made.2. During repetitive nerve stimulation
      at rates between 2 and 10 Hz, e.p.p. amplitudes declined in response to the first
      6-8 stimuli to reach a plateau level which was maintained for 1500 stimuli. At
      higher rates of stimulation some 500-700 stimuli were needed before a plateau
      level of amplitude was reached. It was demonstrated that these amplitude changes
      reflected similar changes in the quantal release of ACh.3. Tubocurarine in a
      concentration of 4 x 10(-8) g/ml. had no effect on quantal release but did reduce
      quantal size. In the presence of tubocurarine, 8 x 10(-8) g/ml., small reductions
      in the quantum content of the first e.p.p. in response to a train of stimuli and
      the maintained quantal release were observed. In the presence of tubocurarine 4 x
      10(-7) g/ml., the quantum content of the first e.p.p. and the maintained release
      were further reduced, to the level previously described for curarized
      preparations. At this concentration a significant effect of tubocurarine upon the
      presynaptic measurements could be detected (t test). Studies on single junctions
      revealed that the post- and presynaptic effects of tubocurarine developed with
      different time courses.4. Neuromuscular preparations in vivo have been reported
      to be much more resistant to maintatined stimulation than curarized neuromuscular
      preparations in vitro. It is suggested that this disparity is explained by the
      presynaptic action of tubocurarine.5. From the quantal release rates of the
      present investigation and reports of ACh release/stimulus/end-plate in previous
      investigations it can be calculated that a quantum of ACh contains between 12,000
      and 21,000 molecules.

PMID- 4346990
TI  - Synaptic action on Clarke's column neurones in relation to afferent terminal
      size.
AB  - 1. Excitatory post-synaptic potentials (e.p.s.p.s) were recorded intracellularly
      from Clarke's column neurones (DSCT neurones) of the cat in response to adequate
      stimuli applied to a variety of sensory receptors.2. The amplitude of e.p.s.p.s
      so produced varied from less than 0.2 mV to more than 2-3 mV. The amplitude
      distribution of e.p.s.p.s suggested that the mean number of ;quanta' of
      transmitter released by one impulse varied widely from one fibre to another
      arising from a given type of sensory receptor.3. The average amplitude of
      e.p.s.p.s evoked by single afferent impulses was significantly smaller for
      cutaneous inputs than for muscle or joint inputs. However, synaptic action on
      DSCT neurones produced by different sensory inputs was equally greater, on the
      average, than that on spinal motoneurones.4. Both small and large e.p.s.p.s in
      DSCT neurones failed to increase in amplitude during post-synaptic
      hyperpolarization applied through the cell body. This failure could not be
      attributed to possible anomalous rectification in the post-synaptic membrane.5.
      Small and large e.p.s.p.s were comparable in half-decay time, but there was a
      positive correlation between amplitude and time-to-peak of e.p.s.p.s. It is
      suggested that the locations of synapses responsible for small and large
      e.p.s.p.s are intermingled on the dendrites and that large e.p.s.p.s are
      associated with a longer duration of transmitter action than small e.p.s.p.s.6.
      Degenerating terminals of primary afferent fibres on DSCT neurones and
      motoneurones were examined with the electron microscope after chronic section of
      the dorsal roots.7. Dendritic degenerating terminals showed no significant
      difference in size between motoneurones and DSCT neurones. Degenerating ;giant'
      terminals were found on DSCT neurones, but they were located only on or very
      close to the cell body.8. It is concluded that the major factor responsible for a
      large number of ;quanta' of transmitter released at synapses on DSCT neurones is
      the number of multiple synaptic contacts formed by one afferent fibre rather than
      the size of individual synapses.

PMID- 4346991
TI  - Transmitter release by mammalian motor nerve terminals in response to focal
      polarization.
AB  - 1. A method is described by which mammalian motor nerve terminals may be
      uniformly polarized by focally applied current, and the extra-cellular potential
      in the synaptic cleft, corresponding to any current, estimated.2. The
      relationship between log m.e.p.p. frequency and local extra-cellular field is
      flat for hyperpolarization and ascends linearly with depolarization. With
      depolarization, m.e.p.p. frequency is multiplied about tenfold for every - 18 mV.
      This characteristic becomes steeper the closer the polarizing electrode to the
      nerve terminal with a limiting value of ten-fold per - 15 mV.3. There exists a
      population of small m.e.p.p.s which are generated at the same end-plate as normal
      m.e.p.p.s.4. Following a prolonged depolarizing pulse there is an increase of
      m.e.p.p. frequency which continues for periods of up to several minutes.5. With
      hyperpolarizing pulses m.e.p.p. frequency may increase in a characteristic
      ;bursty' manner. Similar bursts of m.e.p.p.s also occur spontaneously, but far
      less frequently, without polarization.6. During a depolarizing pulse, m.e.p.p.
      frequency becomes maximal or near maximal within 2 sec. There is little
      subsequent alteration of m.e.p.p. frequency. Numbers of m.e.p.p.s occurring
      during depolarizing pulses follow the Poisson distribution.7. Following a
      depolarizing pulse, numbers of m.e.p.p.s released by a subsequent pulse may be
      either increased or diminished.8. Comparison of the response of m.e.p.p.
      frequency to raised [K] and to extrinsic presynaptic polarization leads to the
      conclusion that the presynaptic transmembrane potential change corresponding to
      any focal current pulse is about two thirds of the local extracellular potential
      field. Hence the slope of the linear portion of the presynaptic transfer function
      is about tenfold per 10 mV presynaptic depolarization.

PMID- 4346993
TI  - The specific effect of potassium on transmitter release by motor nerve terminals
      and its inhibition by calcium.
AB  - 1. There exist two distinct effects of potassium on the transmitter release
      system, one which develops rapidly and another which becomes maximal much more
      slowly. The fast effect is inhibited by raised Ca(2+), which does not inhibit
      transmitter release evoked by depolarizing pulses. Thus the fast effect is not
      secondary to nerve terminal depolarization.2. The fast effect of K(+) was found
      to consist in an increase in the slope of the linear relation between log
      m.e.p.p. frequency and nerve terminal depolarization. This effect is complete
      within a few seconds, is inhibited by raised Ca(2+), and is not produced by
      prolonged focal or electrotonic depolarization, which instead tends to reduce the
      slope of log m.e.p.p. frequency vs. depolarization.3. A slope change effect like
      that of K(+) was not found with ouabain or ethanol, nor did these agents depress
      the slope change effect of K(+). The specific action of K(+) was not exerted on
      release evoked in the absence of Ca(2+) by ethanol, chloral hydrate, or raised
      osmotic pressure.4. It is suggested that the specific action of K(+) is to
      increase the lability of nerve terminal Ca permeability with respect to
      depolarization of the nerve terminal membrane, while the slow effect of K(+)
      simply reflects nerve terminal depolarization, slow to become maximal because of
      diffusion barriers limiting access of raised K(+) to the Ranvier nodes of motor
      axons.

PMID- 4346992
TI  - Cumulative and persistent effects of nerve terminal depolarization on transmitter
      release.
AB  - 1. Following focal depolarization of rat motor nerve terminals there could often
      be observed an ;after-discharge' of m.e.p.p.s with transient frequencies of up to
      1000/sec. This after-discharge was graded with intensity and duration of the
      previous depolarization.2. Following pulses which were relatively short (about 1
      sec) and not too large (< -100 mV local extracellular potential field) the
      logarithm of m.e.p.p. frequency fell exponentially. With larger or longer pulses
      there was a tail to the after-discharge which could persist for several
      minutes.3. M.e.p.p. frequency during an after-discharge was not inhibited
      appreciably by nerve terminal hyperpolarization, raised [Ca] (8 mM) or lowered
      pH.4. Measured as a multiplication of spontaneous m.e.p.p. frequency after
      discharge was depressed in solution containing no Ca(2+) and added 1 mM-MgEDTA
      but equal in 0.125 mM-Ca(2+) or 2 mM-Sr(2+) to that in 2 mM-Ca(2+) or 8 mM
      Ca(2+).5. During an after-discharge the multiplication of m.e.p.p. frequency by
      focal nerve terminal depolarization or raised K(+) was reduced. This phenomenon
      was termed ;uncoupling'.6. It was concluded that the after-discharge is not
      caused by a persistent rise of K(+) concentration in the synaptic cleft, nor by a
      maintained nerve terminal depolarization.7. In preparations depolarized by raised
      K(+) m.e.p.p. frequency during a relatively small focal depolarizing pulse rose
      continuously, after an initial rapid rise, and after the pulse there was a tail
      of increased m.e.p.p. frequency. The magnitude of the rise during the pulse and
      the tail after it were similar on, a logarithmic basis; during both processes the
      logarithm of m.e.p.p. frequency usually followed (approximately) an exponential
      time course.8. The relative magnitude of the slow effect of depolarization, as
      compared with the fast effect, was increased by lowering [Ca] or increasing [Mg],
      and the slow effect of depolarization in contrast to the fast effect was found to
      exist in the presence of Ca reduced to about 10(-7)M, but only during pulses. At
      this [Ca] there was no rapid response to depolarization. At [Ca] about 10(-10)M,
      there was no response at all of m.e.p.p. frequency to nerve terminal
      depolarization.9. The results are discussed, and compared with similar data
      referring to ;facilitation' and ;post-tetanic potentiation'. It is concluded that
      these and the slow effect of depolarization represent the same phenomenon, a
      response of the transmitter release system which can be distinguished from the
      fast response in terms of ionic requirement as well as time course.

PMID- 4346994
TI  - The role of calcium in depolarization-secretion coupling at the motor nerve
      terminal.
AB  - 1. The relation between m.e.p.p. frequency (F) and [Ca] was studied at the mouse
      neuromuscular junction, at varied concentrations of K(+) and at nerve terminals
      depolarized by focal depolarization.2. Under all conditions the relation between
      log F and log [Ca] was sigmoid, with a maximum slope that increased with
      depolarization or raised [K(+)]. In addition, depolarization or raised K(+)
      caused a progressive shift of the sigmoid curve upward and to the left (to
      reduced log [Ca]) and increased the range over which log F could be altered by
      [Ca].3. Reduction of osmotic pressure changed the relation between log F and log
      [Ca] in the same way as increase of depolarization, while increase of osmotic
      pressure did the opposite.4. Raised [Mg] acted in two ways: (a) to shift the
      curve of log F vs. log [Ca] to the right and (b) to reduce maximum Delta log
      F/Delta log [Ca] without altering the range of log F sensitive to [Ca].5. The
      relation between log quantal content of e.p.p.s and log [Ca] was similar to that
      between log m.e.p.p. frequency and log [Ca].6. Individual nerve terminals varied
      in both Ca-dependent and Ca-independent fractions of log F; a large Ca
      independent portion appears to be associated with a low Ca-dependent portion and
      vice versa. With large prolonged depolarization the Ca-independent portion was
      increased, apparently at the expense of the Ca-dependent portion.7. The results
      of all experiments were summarized in terms of parameters found by fitting the
      observed log release -log [Ca] curves to two theoretical equations, each derived
      on the basis of a model: (a) all-or-nothing activation of release probability by
      Ca-complex(es) and (b) graded activation of release probability by Ca
      complex(es).8. On the basis of the all-or-nothing model, from which follows
      alinear relation between F and amounts of Ca complex(es), the number of Ca(2+)
      atoms that ;cooperate' to mediate release appeared to increase progressively with
      presynaptic depolarization, to a value of 4 or more with a presynaptic action
      potential.9. On the basis of the graded activation model, which predicts an
      exponential relation between F and amount of Ca complex, the number of Ca(2+)
      atoms that combine with Ca receptor appears to be independent of presynaptic
      depolarization.10. Various models which could account for the data are discussed.
      It was concluded that all the data are consistent with a model in which:(i)
      quantal release probability is continuously graded with the amount of a simple Ca
      complex (CaX) inside the nerve terminal.(ii) Ca entry is governed by presynaptic
      membrane potential (increasing exponentially with depolarization) and by the
      amount of a Ca complex (Ca(2)Y) on or in the membrane.(iii) Mg(2+) competes with
      Ca(2+) at both receptors, X and Y.(iv) The internal Ca receptor X is also
      increased by presynaptic depolarization.

PMID- 4346995
TI  - [Study of the effect of adenosine cyclic 3'-5'-monophosphate (3'-5'-AMPc) and
      cyclic 3'-5'-phosphodiesterase (3'-5'-FDEc) on the adipose tissue of normal,
      diabetic and obese patients].

PMID- 4346996
TI  - [Iatrogenic lupus induced by anticonvulsive agents].

PMID- 4346997
TI  - [Further observations on knee arthroscopy. Results of a personal experience].

PMID- 4346998
TI  - [Acute suppurative metastatic arthritis due to identified germs].

PMID- 4346999
TI  - [Pseudo-periarthritis of the shoulder. Trapezius paralysis due to surgical spinal
      nerve injury].

PMID- 4347000
TI  - [Peripheral neurologic manifestations of sarcoidosis].

PMID- 4347001
TI  - [Dorsal herniated disc].

PMID- 4347002
TI  - [Hydrocephalus with normal pressure. (Curable demential syndrome)].

PMID- 4347003
TI  - [Short term toxicity and efficacy of 4 different cytosine-arabinoside regimens in
      40 cases of human solid tumors].

PMID- 4347004
TI  - [Hyperosmolar coma in diabetes mellitus. A propos of 21 cases].

PMID- 4347005
TI  - [Waldenstrom's macroglobulinemia with pleuropulmonary, orbital and subcutaneous
      localisation. Favorable effect of chlorambucil].

PMID- 4347007
TI  - [Toxoplasmosis. Difficulties and uncertainties in diagnosis. Report of serveral
      cases].

PMID- 4347006
TI  - [Acute lithium carbonate poisoning. Apropos of a case].

PMID- 4347008
TI  - Melanotic neuroectodermal tumor of infancy.

PMID- 4347009
TI  - Congenital cataract and ectopia lentis. An analysis of 152 patients treated in
      1943-1967.

PMID- 4347010
TI  - [Electronmicroscopic observations on cultured rabbit lens cells infected with
      herpes virus].

PMID- 4347011
TI  - [Herpetic keratitis--from the diagnostic standpoint].

PMID- 4347012
TI  - [Herpetic keratitis: from the virological standpoint].

PMID- 4347014
TI  - Scleroderma.

PMID- 4347013
TI  - Age-dependent changes in the adenylate cyclase and phosphodiesterase activity of
      rat erythrocytes.

PMID- 4347015
TI  - [ACTH].

PMID- 4347016
TI  - [Etiology of hyperaldosteronemia in adrenogenital syndrome].

PMID- 4347017
TI  - [Effect of the intravenous administration of synthetic 1-24ACTH on endogenous
      ACTH].

PMID- 4347018
TI  - [Functioning tumor of the ovary].

PMID- 4347019
TI  - [Experimental studies on acute and direct effects of insulin on the regulation of
      hepatic metabolism. 3. Ineffectiveness of insulin on the hepatic enzymes in obese
      hyperglycemic mice].

PMID- 4347020
TI  - [Gallium-67-scans in gynaecology].

PMID- 4347021
TI  - Cytochemical observations on glucose-6-phosphatase, glucosan phosphorylase,
      glucose-6-phosphate dehydrogenase, and  -glycerophosphate dehydrogenase in chick
      liver cell cultures infected with Trichomonas vaginalis.

PMID- 4347022
TI  - Dual viral infections in two dogs.

PMID- 4347023
TI  - A bovine herpesvirus associated with a disease of the upper respiratory tract of
      feedlot cattle.

PMID- 4347024
TI  - ACTH and nasal polypi.

PMID- 4347025
TI  - The management of tumours of the glomus jugulare.

PMID- 4347026
TI  - Plasma corticosterone level in runt disease.

PMID- 4347027
TI  - Pathogenesis of Abelson-virus-induced murine leukemia.

PMID- 4347028
TI  - Cultivation of cells from a fibroma in a rattlesnake, Crotalus horridus.

PMID- 4347029
TI  - Activation in vitro, by 5-iododeoxyuridine, of a latent virus resembling C-type
      virus in a human sarcoma cell line.

PMID- 4347030
TI  - Seroepidemiologic studies of herpesvirus type 2 and carcinoma of the cervix. II.
      Uganda.

PMID- 4347031
TI  - Radioiodine-labeled antibody test for the detection of membrane antigens
      associated with Epstein-Barr virus.

PMID- 4347032
TI  - Studies with human papilloma virus modeled after known papovavirus systems.

PMID- 4347033
TI  - Mutation and cancer: a model for Wilms' tumor of the kidney.

PMID- 4347034
TI  - Tumor angiogenesis: a quantitative method for histologic grading.

PMID- 4347035
TI  - Immunologic and virologic studies of a nonproducer tumor induced by murine
      sarcoma virus (Harvey).

PMID- 4347036
TI  - Enhancing effect of excess topical vitamin A on Rous sarcomas in chickens.

PMID- 4347037
TI  - Inoculation of calves with particles resembling C-type virus from cultures of
      bovine lymphosarcoma.

PMID- 4347038
TI  - Lung carcinoma of sheep (Jaagsiekte). 3. Lymph node, blood, and immunoglobulin.

PMID- 4347039
TI  - Demonstration of Herpesvirus saimiri-associated antigens in peripheral
      lymphocytes from infected marmosets during in vitro cultivation.

PMID- 4347040
TI  - Infiltrating duct carcinoma of the mammary gland of a rhesus monkey after
      administration of an oral contraceptive: a preliminary report.

PMID- 4347041
TI  - Serologic evidence for a simian-virus-40-like infection of man.

PMID- 4347042
TI  - Delayed hypersensitivity to simian virus 40 tumor cells in BALB-c mice
      demonstrated by a radioisotopic foot-pad assay.

PMID- 4347043
TI  - Effect of vinblastine and colchicine on uptake and release of putative
      transmitters by synaptosomes and on brain actomyosin-like protein.

PMID- 4347044
TI  - RNA and DNA in developing retinae: comparison of a normal with the degenerating
      retinae of C3H mice.

PMID- 4347045
TI  - Metabolism of phosphatidylcholine, phosphatidylinositol and palmityl carnitine in
      synaptosomes from rat brain.

PMID- 4347046
TI  - Metabolic consequences of ethanol oxidation in brains from mice chronically fed
      ethanol.

PMID- 4347047
TI  - The measurement of the inorganic phosphate content of brain in the presence of
      bone fragments.

PMID- 4347048
TI  - Accumulation of adenosine 3',5'-monophosphate in brain slices: interaction of
      local anaesthetics and depolarizing agents.

PMID- 4347049
TI  - Activation of the pathway from locus coeruleus to rat cerebellar Purkinje
      neurons: pharmacological evidence of noradrenergic central inhibition.

PMID- 4347050
TI  - Intrarenal prostaglandin release attenuates the renal vasoconstrictor activity of
      angiotensin.

PMID- 4347051
TI  - Dynamics of binding and release of the polymyxin antibiotics by tissues.

PMID- 4347052
TI  - Duration effects of supraliminal electrical stimuli to the tongue.

PMID- 4347053
TI  - An alternative approach to generalized complementarity.

PMID- 4347054
TI  - Effects of marijuana smoking on the sleep EEG. Preliminary studies.

PMID- 4347055
TI  - [Clinical aspects and prognosis of mammary carcinoma following surgery and
      postoperative radiotherapy].

PMID- 4347056
TI  - [The treatment of sarcomas of cartilage and bone from the surgical point of
      view].

PMID- 4347057
TI  - Recovery of herpes-simplex virus from human trigeminal ganglions.

PMID- 4347058
TI  - Tic douloureux: etiology, refined treatment.

PMID- 4347059
TI  - Further observations on subacute denervation and mammalian motor nerve terminal
      function.

PMID- 4347060
TI  - Neuropsychologic and neurologic follow-up after herpesvirus hominis encephalitis.

PMID- 4347061
TI  - Hypoexcitability of ulnar nerve in patients with normal motor nerve conduction
      velocities.

PMID- 4347062
TI  - Recurrence of nonneoplastic thymus after thymectomy for myasthenia gravis. Report
      of two cases.

PMID- 4347063
TI  - Cytomegalovirus encephalitis in adults.

PMID- 4347064
TI  - Reduction of sympathetic outflow by central administration of L-DOPA, dopamine
      and norepinephrine.

PMID- 4347065
TI  - Morphology of the normal liver cell.

PMID- 4347066
TI  - Renal failure in advanced liver disease.

PMID- 4347067
TI  - Hepatitis virology.

PMID- 4347068
TI  - Lipoproteins and the liver.

PMID- 4347069
TI  - Red blood cell sodium and potassium concentrations in patients with liver
      diseases.

PMID- 4347070
TI  - A method for the extraction, separation and estimation of unconjugated estrone,
      estradiol-17  and estradiol-17  in plasma.

PMID- 4347071
TI  - The subcellular localization of the changes in ribonuclease and phosphatase
      activities of the mouse kidney produced by castration and testosterone.

PMID- 4347072
TI  - [Cytophotometric study of the effect of cortisone on glycogen content of liver
      cells and hepatomas 46 and 48].

PMID- 4347073
TI  - [The angiotensinase activity of  -L-asparaginyl aminopeptidase in the serum of
      normal subjects, in patients with hepatobiliary diseases and during pregnancy].

PMID- 4347074
TI  - Down's syndrome and malignancy.

PMID- 4347075
TI  - Role of cyclic AMP and Ca ++  in mechanical and metabolic events in isometrically
      contracting vascular smooth muscle.

PMID- 4347076
TI  - [Laparoscopy in primary cancer of the liver in adults].

PMID- 4347077
TI  - [Impairment of the respiratory system in workers of an electroporcelain plant].

PMID- 4347078
TI  - Human brain and platelet cyclic adenosine 3',5'-monophosphate phosphodiesterases:
      different response to drugs.

PMID- 4347079
TI  - [Properties of the cyclic AMP binding protein of the bovine adrenal cortex].

PMID- 4347080
TI  - [Fusimotor fibers whose action on the phasic sensitivity of primary endings
      depends on their stimulation frequency].

PMID- 4347081
TI  - Adenovirus pneumonia.

PMID- 4347082
TI  - An outbreak of adenovirus type 7 infection in children in Montreal.
AB  - Thirteen infants and children with adenovirus type 7 infection proved by virus
      isolation are described. High fever, cough and dyspnea were the most frequent
      findings; in infants under 1 year of age wheezing was common. Four patients
      required artificial ventilation. Lobar collapse, consolidation and hyperinflation
      were frequent radiologic findings. None of the symptoms responded to antibiotic
      therapy or bronchodilator drugs. Three patients died (mortality rate of 23%).
      Pathologic findings were compatible with adenovirus type 7 pneumonia, and were
      characterized by a necrotizing bronchitis and bronchiolitis, patchy alveolar
      fibrinopurulent exudate and hyaline membrane formation. Some intra-alveolar
      epithelial cells showed strikingly abnormal nuclei and rare typical halo-outlined
      intranuclear inclusions were seen. Only one of eight survivors had evidence of
      significant chronic chest disease.

PMID- 4347083
TI  - [Granular myoblastoma of the skin].

PMID- 4347085
TI  - Regulation of yeast inorganic-pyrophospphatase activity by divalent cations.

PMID- 4347084
TI  - Antineoplastic and immunosuppressive drugs. II. Therapeutic uses.

PMID- 4347086
TI  - The molecular basis of mutagenesis by methyl and ethyl methanesulfonates.

PMID- 4347087
TI  - Phosphate transfer between 2,3-biphosphoglycerate and monophosphoglycerate
      catalyzed by bisphosphoglycerate phosphatase.

PMID- 4347088
TI  - The substrate specificity of exonuclease A5.

PMID- 4347089
TI  - Studies of glutamate dehydrogenase. Characterization of histidine residues
      involved in the activity and association. Photoactivated labelling with pyridoxal
      5'-phosphate.

PMID- 4347090
TI  - Studies of glutamate dehydrogenase. Modification with 5-diazo-1H-tetrazole and
      glyoxal. Importance of two different amino groups for the binding of 2
      oxoglutarate and NADH.

PMID- 4347091
TI  - Biosynthesis of N-acetylneuraminic acid in Morris hepatomas.

PMID- 4347092
TI  - Reciprocal induction and repression of serine dehydratase and phosphoglycerate
      dehydrogenase by proteins and dietary-essential amino acids in rat liver.

PMID- 4347093
TI  - Inhibition of mitochondrial-protein synthesis in rat small-intestinal epithelium.

PMID- 4347094
TI  - Measurement of plasma renin concentration (PRC) using exogenous substrate and
      radioimmunoassay.

PMID- 4347095
TI  - Calcium and phosphorus metabolism parathyroid hormone, calcitonin and bone
      histology in pseudohypoparathyroidism.

PMID- 4347096
TI  - The response to TRH, LH-RH, metyrapone and vasopressin in patients with
      hypothalamo-pituitary disorders.

PMID- 4347097
TI  - [Treatment with synthetic ACTH of threatened abortion in women with secondary
      hypophyseal insufficiency].

PMID- 4347098
TI  - Perspectives on policy research.

PMID- 4347099
TI  - Column chromatographic determination of polymyxin B sulfate.

PMID- 4347100
TI  - Auer bodies in acute promyelocytic leukemia. Demonstration of their fine
      structure and peroxidase localization.

PMID- 4347101
TI  - The significance of dense core particles in subacute demyelinating disease in an
      adult.

PMID- 4347102
TI  - Thoracic duct drainage during lymphangiography.

PMID- 4347103
TI  - [Electroencephalography in the diagnosis of epilepsy].

PMID- 4347104
TI  - [Diagnostic characteristics of epilepsy in childhood].

PMID- 4347105
TI  - [Hamartomas of the liver].

PMID- 4347106
TI  - [Fetal aldolases and liver tumors].

PMID- 4347107
TI  - [Chemical and physicochemical factors in the effect of steroids].

PMID- 4347108
TI  - Dynamic anatomy of the ulnar nerve at the elbow.

PMID- 4347109
TI  - [Non-transmissible plasmids].

PMID- 4347110
TI  - [Recombination of R plasmids].

PMID- 4347111
TI  - [Disk hernia and syndromes of the conus and cauda equina].

PMID- 4347112
TI  - The ten most common types of brain tumor.

PMID- 4347113
TI  - Vascular patterns in cerebral neoplasms and their differential diagnosis.

PMID- 4347114
TI  - The microbial ecology of the activated sludge process.

PMID- 4347115
TI  - Cystectomy and segmental resection for primary carcinoma of the bladder:
      experience at Ochsner Clinic 1942-1968.

PMID- 4347116
TI  - [Hyperinsulinism due to metastasizing insuloma treated with diazoxide and
      streptozotocin].

PMID- 4347117
TI  - Respiratory infections.

PMID- 4347118
TI  - A current look at feline lymphoma.

PMID- 4347119
TI  - [Histological and enzyme histochemical studies on the effect of testosterone on
      the healing of fractures in rats].

PMID- 4347120
TI  - Coincidental pulmonary granular cell schwannoma and bronchogenic adenocarcinoma.

PMID- 4347121
TI  - Distinctive cytopathic properties of cytomegalovirus recovered from the female
      genital tract.

PMID- 4347122
TI  - Mallory bodies in a case of primary biliary cirrhosis: an ultrastructural and
      morphogenetic study.

PMID- 4347123
TI  - The dependence of pancuronium- and d-tubocurarine-induced neuromuscular blockades
      on alveolar concentrations of halothane and forane.

PMID- 4347124
TI  - Adrenocorticoids and RNA metabolism in kidney. I. Effect of adrenalectomy on RNA
      turnover in various subcellular fractions of rat kidney.

PMID- 4347125
TI  - Stimulation by reticulocyte initiation factors of protein synthesis in a cell
      free system from Krebs II ascites cells.

PMID- 4347126
TI  - Effect of in vitro histone phosphorylation on template activity of rat liver
      chromatin.

PMID- 4347127
TI  - Synchronous cultures of Chlamydomonas reinhardti. Synthesis of repressed and
      derepressed phosphatase during the life cycle.

PMID- 4347128
TI  - Partial purification of cortisol-binding protein from rat liver cytosol and its
      role in transcription.

PMID- 4347129
TI  - [Lipid-protein relations and protein conformation in mitochondria and endoplasmic
      reticulum membranes of the liver of normal rats and rats with tumors].

PMID- 4347130
TI  - Inclusions in human lens capsule and their relationship to senile exfoliation.

PMID- 4347131
TI  - Isolation of cytochrome c abundant mutant of Candida utilis.

PMID- 4347132
TI  - Use of the Du Pont "automatic clinical analyzer" in direct determination of
      lactic acid in plasma stabilized with sodium fluoride.

PMID- 4347133
TI  - Radioimmunoassay of serum renin activity and digoxin concentrations, with use of
      polyethylene glycol to separate free and antibody-bound ligand.

PMID- 4347134
TI  - Use of 3-methyl-2-benzothiazolone hydrazone in an automated colorimetric method
      for determination of triglycerides in plasma or serum.

PMID- 4347135
TI  - Speeded simultaneous turbidimetry of cholesterol in  - and pre- -lipoproteins.

PMID- 4347136
TI  - [Kidney size in the differentiation of the kidney artery stenosis with and
      without activation of the renin-angiotensin system].

PMID- 4347137
TI  - Descending supraspinal effect in tetanus intoxication of the spinal cord.

PMID- 4347138
TI  - Invertebrate central neurons: orthograde degeneration and retrograde changes
      after axonotomy.

PMID- 4347139
TI  - Biochemistry of adenosine triphosphatase activity of avian fast and slow muscle.

PMID- 4347140
TI  - Hyperpolarization of trigeminal primary afferents evoked by stimulation of lumbar
      sympathetic trunk and peripheral nerves.

PMID- 4347141
TI  - Ongoing activity in peripheral nerve: interactions between electrical stimulation
      and ongoing activity.

PMID- 4347142
TI  - [Experimental studies on the mechanism of human chorionic gonadotropin in the
      rabbit ovary].

PMID- 4347143
TI  - Allozyme genotype-environment relationships. I. Variation in natural populations
      of Drosophila pachea.
AB  - Remarkable geographic and seasonal uniformities in gene and genotype frequencies
      were found for four enzyme loci. Principal component analysis revealed two
      patterns of allele frequency changes in three of the allozyme loci (Est-b, Est-c
      and Acph) and one pattern in the Mdh-d locus. These patterns accounted for 90% to
      100% of the variability at these loci. Significant positive correlations were
      obtained between several of the components and the variability in the non
      saponifiable and alkaloid fractions of the senita cactus host plant. The genetic
      variance within a single locality (Guaymas, Mexico) was as great as the variance
      between all localities sampled. This is interpreted as a local founder effect.
      The temporary nature of the rotting cactus breeding site, the delayed maturation
      and the differential maturation rate of females and males are three factors
      proposed to cause forced outbreeding and counter the local founder effect. A
      combination of selection resulting from a direct interaction of the genotype and
      the environment, in addition to migration, is proposed to maintain the uniform
      gene frequencies.

PMID- 4347144
TI  - [Verruca vulgaris--benign tumor of viral etiology and clonal development].

PMID- 4347145
TI  - Mechanisms of the reactions of cytochrome c. II. The rate of reduction of horse
      heart ferricytochrome c by chromium(II).

PMID- 4347146
TI  - Reactions of monomeric cobalt-oxygen complexes. I. Thermodynamics of reaction of
      molecular oxygen with five- and six-coordinate amine complexes of a cobalt
      porphyrin.

PMID- 4347147
TI  - Use of vanadyl(IV) ion as a new spectroscopic probe of metal binding to proteins.
      Vanadyl insulin.

PMID- 4347148
TI  - Adrenocorticotropins. 44. Total synthesis of the human hormone by the solid-phase
      method.

PMID- 4347149
TI  - Cyclic adenosine 3',5'-monophosphate-dependent protein kinase stimulation of
      calcium uptake by canine cardiac microsomes.

PMID- 4347150
TI  - An electron spin resonance study of radicals produced in the photolysis of  -keto
      acids and esters.

PMID- 4347151
TI  - [Cyclic AMP and hormone action].

PMID- 4347152
TI  - [Kidney and cyclic AMP].

PMID- 4347153
TI  - [Lipid metabolism and cyclic AMP].

PMID- 4347154
TI  - [Platelet aggregation and cyclic AMP].

PMID- 4347155
TI  - Behavior of lambda bacteriophage in nicotinamide adenine dinucleotide deficient
      Escherichia coli cells.

PMID- 4347156
TI  - Further simplification of the serum neutralization test with herpes simplex
      virus.

PMID- 4347157
TI  - Various tests in the evaluation of islet cell adenomas.

PMID- 4347158
TI  - [Viral infections and chronic central nervous system diseases].

PMID- 4347159
TI  - [Malignant histiocytoma of the stomach in an 8-year-old boy].

PMID- 4347160
TI  - Oxytocin analogs in the analysis of some phases of hormone action.

PMID- 4347161
TI  - Estrogen action: an inroad to cell biology.

PMID- 4347162
TI  - 18-Hydroxy-11-deoxycorticosterone (18-OH-DOC) secretion in experimental and human
      hypertension.

PMID- 4347163
TI  - Structure, synthesis, and mechanism of action of parathyroid hormone.

PMID- 4347164
TI  - [Histochemical study of cytochrome oxidase and succinate dehydrogenase activity
      in the chick embryo membranous labyrinth].

PMID- 4347165
TI  - Autoregulation of renal blood flow in rabbits immunized with angiotensin II.

PMID- 4347166
TI  - Angiotensin. II. Important role in the maintenance of arterial blood pressure.
AB  - An angiotensin II antagonist, [1-sarcosine, 8-alanine]-angiotensin II, was given
      intravenously to anesthetized dogs with thoracic caval constriction and ascites
      to investigate the role of angiotensin II in the control of arterial pressure.
      The antagonist produced a striking fall in arterial pressure and in aldosterone
      secretion and an accompanying increase in plasma renin activity. In a control
      experiment, normal anesthetized dogs were given the angiotensin analog, but it
      failed to reduce arterial pressure or to influence plasma renin activity. In
      conscious dogs with caval constriction, the antagonist produced essentially the
      same drop in arterial pressure as observed in anesthetized animals. These results
      suggest an important role for angiotensin II in the maintenance of arterial
      pressure by its action on specific receptor sites in arteriolar smooth muscle and
      in the adrenal cortex.

PMID- 4347167
TI  - Norepinephrine-containing neurons: changes in spontaneous discharge patterns
      during sleeping and waking.
AB  - Norepinephrine-containing neurons of the locus coeruleus of the cat were recorded
      with microelectrodes during unrestrained sleeping and waking. The recorded
      neurons were subsequently defined by combined fluorescence histochemistry of
      catecholamines and production of microlesions at recording sites. These pontine
      units show homogeneous changes in discharge patterns with respect to sleep
      stages, firing slowly during drowsy periods and slow wave sleep and firing in
      rapid bursts during paradoxical sleep. These data provide a direct correlation
      between the activity of defined catecholamine-containing neurons and the
      spontaneous occurrence of sleep stages.

PMID- 4347168
TI  - Proton beam radiography in tumor detection.
AB  - Monoenergetic protons are highly sensitive to density variations and are capable
      of giving radiographs of very high contrast. As an initial step in exploring
      their diagnostic potential, protons with energies of 160 million electron volts
      are used in "contact radiography" on tumor-bearing human brain specimens. The
      proton radiographs are compared with x-radiographs taken under identical specimen
      conditions.

PMID- 4347169
TI  - Synthesis of infective poliovirus in BSC-1 monkey cells enucleated with
      cytochalasin B.
AB  - BSC-1 monkey kidney cells were enucleated by two cycles of centrifugation in the
      presence of cytochalasin B. The resulting populations contained 99.5 percent
      enucleated cells. After infection, newly synthesized poliovirus was recovered
      from the enucleated populations. Final virus yield per enucleated cell was about
      one-fifth the yield per infected untreated cell

PMID- 4347170
TI  - Cylic AMP. A mediator of hormone response and its clinical application.

PMID- 4347171
TI  - [Antigenic structure of B. pertussis and its relation to conditions of
      circulation. I. Serotyping of pertussis cultures and study of its determining
      factors].

PMID- 4347172
TI  - [Study of delayed-type hypersensitivity to the administration of Cl. perfringens
      anatoxin].

PMID- 4347173
TI  - [Characteristics of the functional activity of the blood leukocytes and of the
      state of allergy in chronic otitis media].

PMID- 4347174
TI  - Changes in net hydration of DNA during thermal helix-coil transition.

PMID- 4347175
TI  - Assay for the intactness of the outer membrane in isolated mitochondria.

PMID- 4347176
TI  - New federal legislation on alcoholism--opportunities and problems.

PMID- 4347177
TI  - Interconvertible and noninterconvertible forms of rat pyruvate kinase.

PMID- 4347178
TI  - Characterization of two forms of beef heart cyclic nucleotide phosphodiesterase.

PMID- 4347179
TI  - Xanthine oxidase catalyzed oxidation of aldehydes. Oxidation of aliphatic
      aldehydes and 2- and 4-pyridinecarboxaldehyde.

PMID- 4347180
TI  - Effect of spermidine on the activity of DNA polymerases.

PMID- 4347181
TI  - Terminal nucleotides of avian myeloblastosis virus RNA and of ribosomal RNA from
      chicken leukemic myeloblasts.

PMID- 4347182
TI  - [Mutagenesis in blue-green algae Synechocystis aquatilis Sanv].

PMID- 4347183
TI  - [Effect of polypeptide antibiotics on the dehydrogenase activity of intact cells
      and protoplasts (spheroplasts) of bacteria].

PMID- 4347184
TI  - [Resistance of chicks to Herpes simplex virus].

PMID- 4347185
TI  - [Confirmation of the presence of cyclic AMP in lettuce seeds, var. reine de mai].

PMID- 4347186
TI  - [Infrastructure of the eclosion glands in midwife toads (Alytes obstetricans)].

PMID- 4347187
TI  - Some systemic effects of malignant tumors. I. Co-enzyme A levels.

PMID- 4347188
TI  - Retroperitoneal xanthogranuloma and xanthosarcoma (malignant fibrous xanthoma).

PMID- 4347189
TI  - Leiomyomatous hamartoma of the kidney. A clinical and pathologic analysis of 20
      cases from the Kidney Tumor Registry.

PMID- 4347190
TI  - Intrahepatic bile duct carcinoma and C. sinensis infection in Hong Kong.

PMID- 4347191
TI  - [Interneuronic blockaders during the posture-motion regime].

PMID- 4347192
TI  - Heterogeneity of human serum high-density lipoprotein (HDL 2 ).

PMID- 4347193
TI  - The amino acid sequence of bat (Miniopteris schreibersi) cytochrome C.

PMID- 4347194
TI  - [Free radicals and the detoxification system in liver microsomes during
      carcinogenesis].

PMID- 4347195
TI  - Effect of morphine on bradykinin-induced unitary discharges in the spinal cord of
      the rabbit.

PMID- 4347196
TI  - The use of estrogen antagonists in hormone receptor studies.

PMID- 4347197
TI  - A critique on the evaluation and mode of action of antiestrogens.

PMID- 4347198
TI  - Estrogens and antiestrogens.

PMID- 4347199
TI  - Oestrogen uptake by the central nervous system.

PMID- 4347200
TI  - Effect of antiestrogens on uterine estradiol receptors.

PMID- 4347201
TI  - Aspects on the mode of action of antiestrogens and antiprogestogens.

PMID- 4347202
TI  - Changes in 5-hydroxytryptamine metabolism during anaphylactic shock in rats.

PMID- 4347203
TI  - Studies on carcinoembryonic antigen.

PMID- 4347204
TI  - Lysosomal phospholipase A 1  and A 2  of normal and bacillus calmette guerin
      induced alveolar macrophages.
AB  - A single intravenous injection of 0.1 mg of heat-killed Bacillus Calmette Guerin
      (BCG) in 0.1 ml of Bayol F produced an accumulation of activated alveolar
      macrophages (BCG induced). Cells were collected 3.5-4.0 wk after injection.
      Phospholipases A and three lysosomal marker enzymes (acid phosphatase, beta
      glucuronidase, and lysozyme) were measured in homogenates, and the distribution
      of the phospholipases A and lysosomal, mitochondrial, and microsomal marker
      enzymes were examined after sucrose gradient centrifugation of a postnuclear
      (1,000 g) supernatant. Homogenates of normal and BCG-induced macrophages
      contained phospholipases A(1) and A(2) which had optimal activity at pH 4.0 in
      the presence of 2.0 mM ethylenediaminetetraacetate (EDTA). These activities were
      inhibited 50-70% by 2.0 mM CaCl(2). Homogenates of BCG-induced macrophages had
      specific activities of beta-glucuronidase, acid phosphatase, and lysozyme, which
      were increased 1.5- to 3.0-fold over the controls, whether expressed as activity
      per mg protein or activity per 10(7) cells. The specific activities of the
      phospholipases A, on the other hand, were consistently lower than those of the
      control. Distribution of the phospholipases A and the lysosomal marker enzymes
      after sucrose gradient centrifugation suggested that the phospholipases A active
      at pH 4.0 in the presence of EDTA are of lysosomal origin since: (a) BCG
      treatment caused a selective increase in the density of particles which contained
      both the phospholipases A and three lysosomal marker enzymes; and (b) since the
      density of mitochondria and microsomes were not affected by BCG treatment. The
      increase in the density of lysosomes seen here may be related to previously
      described morphologic changes of BCG-induced alveolar macrophages.

PMID- 4347205
TI  - Adenosine 3',5'-cyclic monophosphate in Chlamydomonas reinhardtii. Influence on
      flagellar function and regeneration.
AB  - Adenosine 3',5'-cyclic monophosphate (cAMP) influences both flagellar function
      and flagellar regeneration in Chlamydomonas reinhardtii. The methylxanthine,
      aminophylline, which can cause a tenfold increase in cAMP level in C.
      reinhardtii, inhibits flagellar movement and flagellar regeneration by wild-type
      cells, without inhibiting cell multiplication. Caffeine, a closely related
      inhibitor, also inhibits flagellar movement and regeneration, but it inhibits
      cell multiplication too. Regeneration by a mutant lacking the central pair of
      flagellar microtubules was found to be more sensitive than wild type to
      inhibition by caffeine and to be subject to synergistic inhibition by
      aminophylline plus dibutyryl cAMP. Regeneration by three out of seven mutants
      with different flagellar abnormalities was more sensitive than wild type to these
      inhibitors. We interpret these results to mean that cAMP affects a component of
      the flagellum directly or indirectly, and that the responsiveness of that
      component to cAMP is enhanced by mutations which affect the integrity of the
      flagellum. The component in question could be microtubule protein.

PMID- 4347206
TI  - Evidence for pleiotropic changes in lines of Chinese hamster ovary cells
      resistant to concanavalin A and phytohemagglutinin-P.
AB  - Lines of Chinese hamster ovary cells resistant to the lectins concanavalin A (Con
      A) and phytohemagglutinin-P (PHA-P) have been isolated and characterized. Lines
      were isolated by a stepwise, a single-step, or a cycling single-step procedure,
      from both mutagen-treated and untreated cultures. The resistant lines showed a
      higher efficiency of colony formation in the presence of the appropriate lectin
      than did the wild-type parental line. The cell lines resistant to Con A did not
      exhibit any detectable cross resistance to PHA-P, nor did the PHA-resistant cells
      exhibit cross resistance to Con A. The toxicity of Con A from the wild-type and
      Con A-resistant lines was reduced in the presence of methyl alpha-D
      glucopyranoside; this effect was not seen with the PHA-resistant line. Using
      (125)I-labeled Con A, it was found that Con A was bound preferentially to the
      surface of intact cells, and that the amount of labeled Con A bound to intact
      cells was similar for the wild-type and lectin-resistant lines. The Con A
      resistant lines were found to be more susceptible to the toxic effects of a
      number of different compounds, including cyclic AMP and its dibutyryl derivative,
      sodium butyrate, high concentrations of glucose, phenethyl alcohol, phenol,
      ouabain, and testosterone. It appears that, in these lines, acquisition of
      resistance to Con A gave rise to pleiotropic effects which were detected by
      changes in the sensitivity of the cells to a variety of agents.

PMID- 4347207
TI  - Fine structure of nerve fibers and growth cones of isolated sympathetic neurons
      in culture.
AB  - The leading tips of elongating nerve fibers are enlarged into "growth cones"
      which are seen in tissue culture to continually undergo changes in conformation
      and to foster numerous transitory slender extensions (filopodia) and/or a
      veillike ruffling sheet. After explantation of 1-day-old rat superior cervical
      ganglia (as pieces or as individual neurons), nerve fibers and tips were
      photographed during growth and through the initial stages of aldehyde fixation
      and then relocated after embedding in plastic. Electron microscopy of serially
      sectioned tips revealed the following. The moving parts of the cone, the
      peripheral flange and filopodia, contained a distinctive apparently filamentous
      feltwork from which all organelles except membranous structures were excluded;
      microtubules were notably absent from these areas. The cone interior contained
      varied forms of agranular endoplasmic reticulum, vacuoles, vesicles, coated
      vesicles, mitochondria, microtubules, and occasional neurofilaments and
      polysomes. Dense-cored vesicles and lysosomal structures were also present and
      appeared to be formed locally, at least in part from reticulum. The possible
      roles of the various forms of agranular membranous components are discussed and
      it is suggested that structures involved in both the assembly and degradation of
      membrane are present in the cone. The content of these growing tips resembles
      that in sensory neuron growth cones studied by others.

PMID- 4347208
TI  - The effects of secretagogues on the incorporation of (2- 3 H)myoinositol into
      lipid in cytological fractions in the pancreas of the guinea pig in vivo.
AB  - Stimulation of enzyme secretion in the pancreas on injection of a single dose of
      the cholinergic drug, pilocarpine, was associated with an increased incorporation
      of [2-(3)H]myoinositol into a lipid, which was previously characterized as
      phosphatidylinositol. Stimulation of enzyme secretion by hourly injection of the
      pancreozymin congener, caerulein, led to more increased phosphatidylinositol
      synthesis than with a single injection of pilocarpine. The amylase level of the
      pancreas remained at a low level as long as caerulein was injected, indicating
      continued stimulation of enzyme secretion even though increased
      phosphatidylinositol synthesis ceased after 6 h. Feeding gave the same
      stimulation of phosphatidylinositol synthesis as caerulein. The major synthesis
      of phosphatidylinositol in controls and the stimulation of phosphatidylinositol
      synthesis by pilocarpine was entirely confined to the microsome fraction
      throughout the experiments (up to 18 h). This shows that there is no flow of
      microsomal membrane (smooth- or rough-surfaced endoplasmic reticulum) to other
      membranous structures throughout the secretory cycle and beyond. It is concluded
      that the stimulation of phosphatidylinositol synthesis by pancreatic
      secretagogues is confined to microsomal elements and does not play any role in
      membrane flow.

PMID- 4347209
TI  - Expression of the mitochondrial genome in HeLa cells. IX. Effect of inhibition of
      mitochondrial protein synthesis on mitochondrial formation.
AB  - The effect of selective inhibition of mitochondrial protein synthesis by
      chloramphenicol at 40 or 200 microg/ml on the formation of mitochondria in HeLa
      cells was investigated. HeLa cells, under the conditions used in the present
      work, grow at a decreasing rate for at least four cell generations in the
      presence of 40 microg/ml chloramphenicol, and for two generations in the presence
      of 200 microg/ml chloramphenicol. The progressive cell growth inhibition which
      begins after 2 days of exposure of the cells to 40 microg/ml chloramphenicol is
      immediately or gradually reversible, upon removal of the drug, for periods up to
      at least 8 days of treatment, though there is a progressive loss of cloning
      efficiency. In cells which have been treated for 6-7 days with 40 or 200
      microg/ml of chloramphenicol, mitochondrial protein synthesis occurs at a normal
      or near-normal rate 1 h after removal of the drug. Mitochondria increase normally
      in number and show a normal size and amount of cristae in the presence of either
      concentration of drug. However, in 4-5% of the mitochondrial profiles the cristae
      appear to be arranged in unusual, circular, looped or whorled configuration.

PMID- 4347210
TI  - Mode of mitochondrial formation in HeLa cells.

PMID- 4347211
TI  - Interferon: effect on the saturation density to which mouse cells will grow in
      vitro.

PMID- 4347212
TI  - A labyrinthine structure formed from a transverse tubule of mouse ventricular
      myocardium.

PMID- 4347213
TI  - Phenobarbital-induced, membrane-like scrolls in the oenocytes of Musca domestica
      linnaeus.

PMID- 4347214
TI  - Angiotensin effect on uptake of norepinephrine by synaptosomes.

PMID- 4347215
TI  - Influence of niacinamide administration on brain 5-HT and a possible mode of
      action.

PMID- 4347216
TI  - The effects of acetaldehyde on the kinetics of the energy-dependent phosphate
      induced swelling of rat liver mitochondria.

PMID- 4347217
TI  - [The Rous sarcoma virus as a general factor in carcinogenesis].

PMID- 4347218
TI  - [Detection of RSV-neutralizing antibodies in the fowl using the CAM-test].

PMID- 4347219
TI  - [Stimulation of the fetal adrenals during pregnancy].

PMID- 4347220
TI  - Potency disturbances following Abrodil myelography.

PMID- 4347221
TI  - Nursing care study; carcinoma of the stomach complicated by metastases.

PMID- 4347222
TI  - [A case of pleomorphic adenoma of the parotid gland with malignant
      transformation].

PMID- 4347223
TI  - Toxic effect of the fruit of Passiflora adenopoda D. C. on humans: phytochemical
      determination.

PMID- 4347224
TI  - Vitamin C and respiratory infections.

PMID- 4347225
TI  - [The value of an ACTH stimulation test for assessing the hypothalamus-hypophysis
      adrenal cortex axis in patients treated with glucocorticoid preparations].

PMID- 4347226
TI  - The phosphorylation of 3'-deoxy-3'-fluorothymidine and its incorporation into DNA
      in a cellfree system from tumor cells.

PMID- 4347227
TI  - [Low density lipoproteins (LDL) in the human umbilical cord blood].

PMID- 4347228
TI  - Study on the intracellular mechanism of LH release in the anterior pituitary.

PMID- 4347229
TI  - Diagnosis and management of insulinoma.

PMID- 4347230
TI  - Quantitative gas chromatographic analysis of amino acids on a short glass
      capillary column.

PMID- 4347231
TI  - Fractionation of microbial DNA strands on poly I-coated kieselguhr.

PMID- 4347233
TI  - [Type-C-particle viruses in a transplantable hamster mesothelioma].

PMID- 4347232
TI  - Release of aminoacyl transfer ribonucleic acid from transfer ribonucleic acid
      synthetase studied by rapid molecular sieve chromatography.

PMID- 4347234
TI  - [C-particle viruses in cell-free induced leukoses of Syrian hamsters and rat
      reticuloses].

PMID- 4347235
TI  - [Immunologic cross reactions between virus producing and non-virus producing
      murine mammary carcinoma].

PMID- 4347236
TI  - Clinical course and complications in Hodgkin's disease.

PMID- 4347237
TI  - The binding of hydrogen and calcium ions by Tamm-Horsfall glycoprotein.

PMID- 4347238
TI  - A study of the cystine-containing apolipoprotein of human plasma high density
      lipoproteins: characterization of cyanogen bromide and tryptic fragments.

PMID- 4347239
TI  - Backbone folding of immunoglobulin light and heavy chains: a comparison of
      predicted  -bend positions.

PMID- 4347240
TI  - [Effect of 2 conditioning stimuli on presynaptic inhibition of the 1st negative
      component of spinal cord dorsal surface potential].

PMID- 4347241
TI  - [Role of lipid systems in liver carcinogenesis caused by the combined action of 2
      aminoacetylfluorene and heated sunflower oil].

PMID- 4347242
TI  - The effect of compound F6066 on rat luteinizing hormone (LH) and follicle
      stimulating hormone (FSH) release in vitro.

PMID- 4347243
TI  - Distribution and binding of J 131 -human chorionic gonadotropin (HCG) in
      different organs of pseudopregnant female rats.

PMID- 4347244
TI  - [Cytochemical characteristics of the aseptic inflammation type foreign body
      (cytochemical studies of some enzymes from the group of oxidoreductases and
      esterases)].

PMID- 4347245
TI  - Ultraviolet-sensitive mutator mutU4 of Escherichia coli inviable with polA.
AB  - Attempts to transduce the ultraviolet-sensitive mutator lesion mutU4 into strains
      deficient in deoxyribonucleic acid polymerase I (polA) were unsuccessful. Mutator
      recombinants were found when the polA recipient had first been reverted to Pol(+)
      by selection for resistance to methyl methanesulfonate. The inviability of the
      mutU4 polA double mutant was demonstrated by a reduction in the absolute number
      of transductants when the recipient was polA as compared with Pol(+), and
      selection was made for markers very close to mutU4. Double mutants containing
      mutU4 and polA4, which determines a cold-sensitive polymerase, were unable to
      grow at 24 C, the nonpermissive temperature.

PMID- 4347246
TI  - Spin-labeling studies on the membrane of a facultative thermophilic bacillus.
AB  - Spin-labeling studies were conducted to elucidate the rigidity and viscosity of
      the membrane of a facultative thermophilic bacillus. By employing nitroxide
      stearate probes, it was observed that this fatty acid was incorporated into the
      membrane fraction. Electron spin resonance spectroscopy indicated that cells
      grown at 55 C contained a membrane which was more rigid and viscous than the
      membrane from cells grown at 37 C.

PMID- 4347248
TI  - A new crystal-containing cell in human adrenal cortex.
AB  - Electron microscope examination of the adrenal cortex from three male human
      subjects revealed a special type of cell occurring in periendothelial spaces, in
      all adrenal cortex zones. It is a clear, spindle-shaped cell the principal
      cytoplasmic features of which are crystalline inclusions with a structure similar
      to that of the Reinke crystals of human testicular interstitial cells and an
      abundance of microfilaments. Enzymatic digestions with pronase, pepsin, and
      ribonuclease were performed, and no digestion of the crystals was obtained. The
      crystals had no peroxidase or acid phosphatase activities. This cell appears to
      be exclusive to human males and it may be related to adrenal androgen secretion.

PMID- 4347247
TI  - Comparative transport activity of intact cells, membrane vesicles, and mesosomes
      of Bacillus licheniformis.
AB  - Sodium ion was shown to stimulate strongly the transport of l-glutamic acid into
      cells of Bacillus licheniformis 6346 His(-). Lithium ion had a slight capacity to
      replace Na(+) in this capacity, but K(+) was without effect. Three of five amino
      acids tested. l-glutamic acid, l-aspartic acid, and l-alanine, were concentrated
      against a gradient in the cells. Intracellular pools of these amino acids were
      extractable with 5% trichloroacetic acid. Pools of l-histidine and l-lysine could
      not be detected. No evidence of active transport of lysine into cells could be
      detected, and histidine was taken up in the absence of chloramphenicol but not in
      its presence. The uptake of glutamic acid by membrane vesicle preparations was
      strongly stimulated by reduced nicotinamide adenine dinucleotide (NADH) and to a
      lesser extent by succinate. The presence of phenazine methosulfate increased
      uptake in the presence of succinate. Either l- or d-lactate and adenosine
      triphosphate were without effect. None of these compounds stimulated the uptake
      of glutamic acid by mesosomes, although some mesosome preparations contained
      separable membrane which was very active. NADH strongly stimulated the uptake of
      aspartic acid and alanine by membrane vesicles but had only a slight effect on
      the uptake of histidine and lysine. No evidence of active transport of any of the
      amino acids into mesosomes could be detected either in the presence or absence of
      NADH. NADH stimulation of the uptake of glutamic acid by membrane vesicles was
      destroyed by exposure to light of 360 nm; this inactivation was reversible by
      vitamin K(2(5)) or K(2(10)). Sodium ion stimulated transport of glutamic acid by
      membrane vesicles.

PMID- 4347250
TI  - Cytochalasin B. VI. Competitive inhibition of nucleoside transport by cultured
      Novikoff rat hepatoma cells.
AB  - Cytochalasin B competitively inhibits the transport of uridine and thymidine by
      Novikoff rat hepatoma cells growing in suspension culture with apparent K(i)'s of
      2 and 6 microM, respectively, but has no effect on the intracellular
      phosphorylation of the nucleosides. Choline transport is not affected by
      cytochalasin B. Results from pulse-chase experiments indicate that cytochalasin B
      has no direct effect on the synthesis of RNA, DNA, or uridine diphosphate-sugars.
      The inhibition of uridine and thymidine incorporation into nucleic acids by
      cytochalasin B is solely the consequence of the inhibition of nucleoside
      transport.

PMID- 4347249
TI  - Thymidine transport by cultured Novikoff hepatoma cells and uptake by simple
      diffusion and relationship to incorporation into deoxyribonucleic acid.
AB  - The initial rate of thymidine-(3)H incorporation into the acid-soluble pool by
      cultured Novikoff rat hepatoma cells was investigated as a function of the
      thymidine concentration in the medium. Below, but not above 2 microM, thymidine
      incorporation followed normal Michaelis-Menten kinetics at 22 degrees , 27
      degrees , 32 degrees , and 37 degrees C with an apparent K(m) of 0.5 microM, and
      the V(max) values increased with an average Q(10) of 1.8 with an increase in
      temperature. The intracellular acid-soluble (3)H was associated solely with
      thymine nucleotides (mainly deoxythymidine triphosphate [dTTP]). Between 2 and
      200 microM, on the other hand, the initial rate of thymidine incorporation
      increased linearly with an increase in thymidine concentration in the medium and
      was about the same at all four temperatures. Pretreatment of the cells with 40 or
      100 microMp-chloromercuribenzoate for 15 min or heat-shock (49.5 degrees C, 5
      min) markedly reduced the saturable component of uptake without affecting the
      unsaturable component or the phosphorylation of thymidine. The effect of p
      chloromercuribenzoate was readily reversed by incubating the cells in the
      presence of dithiothreitol. Persantin and uridine competitively inhibited
      thymidine incorporation into the acid-soluble pool without inhibiting thymidine
      phosphorylation. At concentrations below 2 microM, thymidine incorporation into
      DNA also followed normal Michaelis-Menten kinetics and was inhibited in an
      apparently competitive manner by Persantin and uridine. The apparent K(m) and
      K(i) values were about the same as those for thymidine incorporation into the
      nucleotide pool. The over-all results indicate that uptake is the rate-limiting
      step in the incorporation of thymidine into the nucleotide pool as well as into
      DNA. The cells possess an excess of thymidine kinase, and thymidine is
      phosphorylated as rapidly as it enters the cells and is thereby trapped. At low
      concentrations, thymidine is taken up mainly by a transport reaction, whereas at
      concentrations above 2 microM simple diffusion becomes the principal mode of
      uptake. Evidence is presented that indicates that uridine and thymidine are
      transported by different systems. Upon inhibition of DNA synthesis, net thymidine
      incorporation into the acid-soluble pool ceased rapidly. Results from pulse-chase
      experiments indicate that a rapid turnover of dTTP to thymidine may be involved
      in limiting the level of thymine nucleotides in the cell.

PMID- 4347251
TI  - The interaction of soluble horseradish peroxidase with mouse peritoneal
      macrophages in vitro.
AB  - The in vitro interaction of soluble horseradish peroxidase (HRP) with homogeneous
      mono layers of mouse macrophages has been studied using sensitive biochemical and
      cytochemical techniques. The compartmentalization of HRP in extracellular and
      intracellular sites has been quantitatively evaluated. A significant fraction is
      bound to a serum-derived layer, which coats the surface of culture vessels and
      may be removed by appropriate washes. Macrophages interiorize HRP as a solute in
      pinocytic vesicles without appreciable binding of the glycoprotein to the plasma
      membrane. Uptake is directly proportional to the concentration of HRP in the
      culture medium. 1 x 10(6) cells ingest 0.0025% of the administered load per hr
      over a wide range of concentrations. Cytochemically, all demonstrable HRP is
      sequestered within the endocytic vesicles and secondary lysosomes of the vacuolar
      apparatus. After uptake, the enzymatic activity of HRP is inactivated
      exponentially with a half-life of 7-9 hr, until enzyme is no longer detectable.
      When macrophages have pinocytosed trace-labeled HRP-(125)I, cell-associated
      isotope disappears with a t (1/2) of 20-30 hr and they release monoiodotyrosine
      (125)I into the culture medium. We were unable to obtain evidence that
      significant amounts of HRP (>2%) can be exocytosed after uptake, can exist intact
      on the cell surface, or can be digested extracellularly. It is difficult to
      reconcile these observations with several of the postulated mechanisms whereby
      macrophages are thought to play a prominent role in the induction of an immune
      response.

PMID- 4347253
TI  - Modifications of lincomycin involving the carbohydrate portion. II. Analogues
      with D-gluco- and D-ido-stereochemistry.

PMID- 4347254
TI  - [Islet cell adenoma and arteriography].

PMID- 4347252
TI  - Effect of adenosine 3'-5'-cyclic monophosphate on cell proliferation.
AB  - Secondary cultures of human diploid fibroblasts, which demonstrate density
      dependent inhibition of cell growth, were used to study the effect of adenosine
      3'-5'-cyclic monophosphate (cAMP) on cell proliferation. DNA synthesis in
      nonconfluent cultures and in contact-inhibited cultures stimulated to grow by
      refeeding with fresh medium was found to be inhibited by exogenous cAMP. The
      properties of this inhibition of DNA synthesis, together with the alterations in
      cAMP metabolism observed in confluent cultures of cells stimulated with fresh
      medium to resume growth, strongly suggest that cAMP is involved in contact
      inhibition of cell proliferation.

PMID- 4347255
TI  - Effect of catecholamine analogs on control of actomyosin by native tropomyosin
      and calcium: the nature of the negative inotropic receptor.

PMID- 4347256
TI  - Studies of the presynaptic effect of  -bungarotoxin on neuromuscular
      transmission.

PMID- 4347257
TI  - Inhibition of adrenergic neurotransmission by parasympathomimetics in the rabbit
      ear artery.

PMID- 4347259
TI  - [2 unusual aspects of synovial sarcoma of the knee].

PMID- 4347258
TI  - Vasoconstriction produced by hallucinogens on isolated human and sheep umbilical
      vasculature.

PMID- 4347260
TI  - -Foetoprotein in rats with hepatomas induced by aflatoxin B 1 .

PMID- 4347261
TI  - Suppression of pituitary-adrenal response to stress with physiological plasma
      levels of corticosterone in the female rat.

PMID- 4347262
TI  - [Subacute form of herpetic meningoencephalitis].

PMID- 4347263
TI  - Eczema herpeticum and pregnancy.

PMID- 4347264
TI  - Clear cell adenocarcinoma in young women.

PMID- 4347265
TI  - [Surgical treatment of primary carcinoma of the liver].

PMID- 4347266
TI  - Respiratory responses to ACTH and dexamethasone in unanesthetized goats.

PMID- 4347267
TI  - [Polygraphic recording of night sleep during acute encepahlitis with opsoclonus].

PMID- 4347268
TI  - [Posttraumatic palatal and ocular myoclonia. Polygraphic study during wakefulness
      and sleep].

PMID- 4347269
TI  - [Role of the posterior longitudinal fasciculus and supranuclear tracts in ocular
      motoricity during the awake state and paradoxical sleep].

PMID- 4347270
TI  - [Eye movements during sleep].

PMID- 4347271
TI  - Possible implications for medicine of RNA-directed DNA synthesis.

PMID- 4347272
TI  - Proinsulin.

PMID- 4347273
TI  - Nuclear magnetic resonance studies of the dynamic aspects of molecular structure
      and interaction in biological systems.

PMID- 4347274
TI  - [Preparation of 6-aminopenicillanic acid].

PMID- 4347275
TI  - [Polyphosphate formation by Proactinomyces fructiferi var. ristomycini--producer
      of the antibiotic ristomycin].

PMID- 4347276
TI  - [Solubilization of vitamin D 3  in a micellar solution].

PMID- 4347277
TI  - [Degranulation of rat mast cells by phytohemagglutinin].

PMID- 4347278
TI  - [Study of vitamin D 3  absorption with a micellar solution of H 3 -labeled
      vitamin D 3  in the in situ isolated intestinal loop of rats].

PMID- 4347279
TI  - [Histoenzymologic study of the pineal gland in rats adapted to cold].

PMID- 4347280
TI  - [Chlorpromazine, piracetam and phospholipid metabolism of rat brain].

PMID- 4347281
TI  - On the development of amino acid transport systems.

PMID- 4347282
TI  - [Conception of the function of the central auditory pathways].

PMID- 4347283
TI  - [Stimulation of gluconeogenesis from lactate in isolated perfused rat liver using
      N6,02'-dibutyryl-adenosine-3',5'-monophosphate].

PMID- 4347284
TI  - A pharmacological analysis of the response of dog anterior mesenteric vein to
      transmural electrical stimulation.

PMID- 4347285
TI  - Elicitation of periods of inhibition in human muscle by stimulation of cutaneous
      nerves.

PMID- 4347286
TI  - En bloc resection of the shoulder girdle: technique and indications. Report of a
      case.

PMID- 4347287
TI  - Scaphoid and lunate dislocation. Report of a case in a patient with peripheral
      neuropathy.

PMID- 4347288
TI  - An enzymatic function associated with transformation of fibroblasts by oncogenic
      viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor
      viruses.
AB  - Chick, hamster, mouse, and rat embryo fibroblast cultures, transformed by either
      DNA or RNA viruses, show fibrinolytic activity under suitable conditions of
      growth and in appropriate media; normal counterpart cultures do not. The
      fibrinolysin is produced by the interaction of two protein factors: one of these,
      a cell factor, is released by transformed cells and accumulates in the medium
      when cultures are incubated in the absence of scrum. The second factor, the serum
      factor, is a specific protein that is present in sera of many avian and mammalian
      species, including man. Not all sera yield fibrinolysin on interaction with any
      given transformed cell factor, and the spectrum of activating sera is distinctive
      for each cell factor. This pattern appears to be determined by the cell type,
      rather than by the transforming virus. An important role for the fibrinolysin in
      oncogenic transformation is suggested by the following correlations. (a) The
      initial appearance of fibrinolysin precedes the morphological change after the
      transfer to permissive temperatures of chick fibroblast cultures infected with a
      temperature-sensitive mutant of RSV. (b) The initiation of fibrinolysis and of
      morphological change both require the synthesis of new protein, but not the
      synthesis of either DNA or rRNA. (c) The activity of the fibrinolysin is
      correlated with the retention of abnormal morphology in hamster cells transformed
      by SV-40. (d) The sera of normal chicks effectively activate fibrinolysis with
      the cell factor from transformed chick cells. In contrast the sera of chicks with
      RSV tumors do not; these contain an inhibitor of the fibrinolytic activity.

PMID- 4347289
TI  - Epstein-Barr virus. Heterophile responses in squirrel monkeys inoculated with
      virus-transformed autologous leukocytes.
AB  - Epstein-Barr virus (EBV)-transformed autologous lymphoblasts were repeatedly
      inoculated into three squirrel monkeys. Each animal developed the heterophile
      antibodies of infectious mononucleosis and EBV-specific antibodies. After
      serologic responses had disappeared or markedly declined, the animals were
      challenged with either whole cells, cell filtrate, or cell ghosts. Animals
      challenged with living cells and cell ghosts developed agglutinin responses; the
      recipient of filtrate did not. The results suggest that EBV induces the
      appearance of the infectious mononucleosis heterophile antigen on the transformed
      cell membrane.

PMID- 4347290
TI  - An enzymatic function associated with transformation of fibroblasts by oncogenic
      viruses. I. Chick embryo fibroblast cultures transformed by avian RNA tumor
      viruses.
AB  - Chick embryo fibroblast cultures develop fibrinolytic activity after
      transformation by Rous sarcoma virus (RSV). This fibrinolytic activity is not
      present in normal cultures, and it does not appear after infection with either
      nontransforming strains of avian leukosis viruses or cytocidal RNA and DNA
      viruses. In cultures infected with a temperature sensitive mutant of RSV the
      onset of fibrinolysis appears after exposure to permissive temperatures and
      precedes by a short interval the appearance of morphological evidence of
      transformation. See PDF for Structure The rate of fibrinolysis in transformed
      cultures depends on the nature of the serum that is present in the growth medium:
      some sera (e.g., monkey or chicken serum) promote high enzymatic activity, while
      others (calf, fetal bovine) do not. Some sera contain inhibitors of the
      fibrinolysin. Based on the effect of a small number of known inhibitors, at least
      one step of the fibrinolytic process shows specificity resembling that of
      trypsin. The sera of sarcoma-bearing chickens contain an inhibitor of the
      fibrinolysin, whereas normal chicken sera do not. For general discussion,
      conclusions, and summary see the accompanying paper, part II, (J. Exp. Med.
      137:112).

PMID- 4347291
TI  - Hormonal changes in ewes and their fetuses at parturition.

PMID- 4347292
TI  - Small-angle x-ray scattering of human serum high-density lipoproteins.

PMID- 4347293
TI  - [Cyclic AMP of the brain].

PMID- 4347294
TI  - [A comparative evaluation of anti-schistosomiasis preparations].

PMID- 4347295
TI  - [Detection of group-specific antigen on avian sarcoma-leukosis viruses using the
      indirect immunofluorescent technic].

PMID- 4347296
TI  - Treatment of myasthenia gravis.

PMID- 4347297
TI  - Effect of folic acid on plasma renin activity in rats.

PMID- 4347298
TI  - Unsuspected tuberculosis in a cancer patient.

PMID- 4347299
TI  - Pseudohypohyper what?

PMID- 4347300
TI  - The clinical utility of brainscanning in nuclear medicine.

PMID- 4347301
TI  - Prostaglandin (PGA1), angiotensin and renal function.

PMID- 4347302
TI  - [Labelling of 3'-terminal of RNA].

PMID- 4347303
TI  - Studies in familial (medullary) thyroid carcinoma.

PMID- 4347304
TI  - [Study of the synovial fluid and plasma in articular chondrocalcinosis].

PMID- 4347305
TI  - [Review of recent reports on the pathology of articular cartilage. 3. Repair.
      Influence of pressure. Role of hormones. Experimental study. Aging].

PMID- 4347307
TI  - Diagnostic problems in adenoviral disease.

PMID- 4347306
TI  - Tektite II: medical supervision of the scientists in the sea. XIV. Biochemical,
      hematological, and endocrine studies.

PMID- 4347308
TI  - Clinical appraisal of an inactivated bovine rhinotracheitis/parainfluenza-3
      vaccine with pasteurella bacterin.

PMID- 4347309
TI  - [Monoamine distribution in the corpora pedunculata of the brain of Acheta
      domesticus. L. (Orthoptera, Insecta). Histochemistry, compared with structure and
      ultrastultrastructure].

PMID- 4347310
TI  - [Experimental production of air-borne infections (review)].

PMID- 4347311
TI  - Functional regulation of mammalian ribonucleotide reductase.

PMID- 4347312
TI  - New aspects of polyamine biosynthesis in eukaryotic organisms.

PMID- 4347313
TI  - Two carbamyl phosphate synthetases of mammals: specific roles in control of
      pyrimidine and urea biosynthesis.

PMID- 4347314
TI  - Mode of action of specific inactivating enzymes for pyridoxal enzymes and NAD
      dependent enzymes and their biological significance.

PMID- 4347315
TI  - Regulatory characteristics of lactate dehydrogenases.

PMID- 4347316
TI  - Isozyme studies on adult, regenerating, precancerous and developing liver in
      relation to findings in hepatomas.

PMID- 4347318
TI  - Intrauterine electroencephalogram of the sheep fetus.

PMID- 4347317
TI  - Correlations between clinical and laboratory findings in virus infection of the
      female genital tract.

PMID- 4347319
TI  - Skin test for amebiasis: an appraisal.

PMID- 4347320
TI  - [Microcalcification in breast diseases. Histological and ultrastructural
      aspects].

PMID- 4347321
TI  - Guillain-Barre syndrome. Increased lymphoproliferative potential.

PMID- 4347322
TI  - Chronic herpes simplex virus infection. Initiation in hamsters upon implantation
      of infected nonpermissive glial cells.

PMID- 4347323
TI  - The central nervous system in Fabry's disease. An ultrastructural study.

PMID- 4347324
TI  - Myotonia induced by monocarboxylic aromatic acids. A possible mechanism.

PMID- 4347325
TI  - Scanning electron microscopic study of skeletal muscle. Normal, destrophic, and
      neurogenic atrophic muscle in mice and humans.

PMID- 4347326
TI  - Prolonged paralysis in pseudocholinesterase deficiency.

PMID- 4347327
TI  - Polymyositis with intranuclear inclusions. A light and electron microscopic
      study.

PMID- 4347328
TI  - Metabolism of I-hydroxy-2-ketoheptadecane in myelinating brain.

PMID- 4347329
TI  - Incorporation of 2-deoxy-D-glucose into glycolipids of normal and SV40
      transformed hamster cells.

PMID- 4347331
TI  - Growth of establishes lymphocytes in selective media: application to studies of
      inborn metabolic errors and somatic mutations.

PMID- 4347330
TI  - Strain L fibroblast lipases. Purification and properties.

PMID- 4347333
TI  - Biohazards of long-term lymphocyte cultures.

PMID- 4347332
TI  - The role of Epstein-Barr virus in establishing long-term human lymphocyte
      cultures.

PMID- 4347334
TI  - Methodology for cultured human lymphoid cells.

PMID- 4347335
TI  - Spontaneous and induced transformation of human leukocytes in vitro.

PMID- 4347336
TI  - The lymphocyte in culture: historic perspective.

PMID- 4347337
TI  - Herpesvirus hominis infection in patients with myeloproliferative and
      lymphoproliferative disorders.
AB  - Infection with Herpesvirus hominis, often associated with oral ulceration, was
      found to be more frequent in patients with myeloproliferative and
      lymphoproliferative disorders than in normal populations or patients with other
      diseases. This increased frequency was not associated with any deficiency of the
      humoral antibody response, suggesting a possible impairment of cell-mediated
      immunity. The otherwise untreatable oral lesions appeared to respond effectively
      to local irradiation.

PMID- 4347338
TI  - Transient cranial mononeuropathy.

PMID- 4347339
TI  - Effects of postovulatory estrogen on progesterone and prostaglandin F levels in
      the monkey.

PMID- 4347340
TI  - Terminal oxidations in Bacillus brevis. Soluble reduced nicotinamide adenine
      dinucleotide oxidase activity in Bacillus brevis.

PMID- 4347341
TI  - Multiplication of Mycobacterium lepraemurium in cell-free medium containing  
      ketoglutaric acid and cytochrome c.

PMID- 4347342
TI  - The levels of cyclic AMP during substrate-accelerated death.

PMID- 4347343
TI  - Conidiophore and spore development in Aspergillus nidulans.

PMID- 4347344
TI  - [Levels of HI antibody against Japanese encephalitis virus and the effect of
      vaccination in inpatients of a tuberculosis sanatorium in Fukuoka City].

PMID- 4347345
TI  - [Refractory period and repetitive stimulation transmission in human mixed
      peripheral nerves].

PMID- 4347346
TI  - Nurses as multiple therapists.

PMID- 4347347
TI  - The nurse-therapist: a staff nurse position which emphasizes clinical practice.

PMID- 4347348
TI  - Teaching nurses to care for the dying patient.

PMID- 4347349
TI  - The role of the nurse in crisis intervention and suicide prevention.

PMID- 4347351
TI  - Megavitamins: pro and con.

PMID- 4347350
TI  - Leadership and social change in 1973?

PMID- 4347352
TI  - The American Association of Retired Persons.

PMID- 4347353
TI  - Phasing out a state mental hospital.

PMID- 4347354
TI  - Gerontological nursing: where the action is.

PMID- 4347356
TI  - [Hemodialysis and hypertension].

PMID- 4347355
TI  - [Long-term problems in hemodialysis].

PMID- 4347357
TI  - [Neuropathy and encephalopathy in dialysis treatment].

PMID- 4347358
TI  - [Autopsy case of hepatocellular carcinoma starting with symptoms of brain tumor].

PMID- 4347359
TI  - [Electroencephalographic test during overnight sleep].

PMID- 4347360
TI  - Effects of vitamin E on toxicoderma associated with liver damage. Case report.

PMID- 4347361
TI  - [Purification of para-influenza virus 3].

PMID- 4347362
TI  - [Thrombopenic syndromes and platelet disorders in childhood. Conclusions].

PMID- 4347363
TI  - Viewing the past as prologue for changes today and tomorrow.

PMID- 4347364
TI  - Studies on the site of renal salt loss in a patient with Bartter's syndrome.

PMID- 4347365
TI  - Thiamine deficiency in adult hospital patients.

PMID- 4347366
TI  - [Community mental health services and home visits. I].

PMID- 4347367
TI  - [Care after hospital care].

PMID- 4347368
TI  - [Structure and functions of smooth muscle cells].

PMID- 4347369
TI  - [Skin thermal analyzer].

PMID- 4347370
TI  - [Sleep (neurophysiological, autonomic, psychological, chemical and
      pathophysiological aspects)].

PMID- 4347372
TI  - Models of copper-protein interaction: the crystal structure of (glycyl-L
      histidylglycinato)-copper (II) sodium perchlorate hydrate.

PMID- 4347371
TI  - [Neurophysiological mechanisms of sleep].

PMID- 4347373
TI  - [Histochemical studies on zonal enzyme distribution in the epididymal epithelium
      of the rat].

PMID- 4347374
TI  - [Histotopochemistry of glycerol phosphatedehydrogenases in the kidney of male
      albino rats].

PMID- 4347375
TI  - Histochemistry of hydroxysteroid dehydrogenases in the testis, adrenocartical
      tissue, and corpuscles of Stannius of Pseudopleuronectes americanus.

PMID- 4347376
TI  - [Metastasizing gliosarcoma].

PMID- 4347377
TI  - [Visual field and intracarotid sodium amytal in man].

PMID- 4347378
TI  - Reciprocal inhibitary effect of 5-iodo-2'-deoxyuridine and thymidine into the
      cells infected with herpes simplex virus.

PMID- 4347379
TI  - Journal's culpa?

PMID- 4347380
TI  - [Ultrastructural changes in Harding-Passey melanoma by transfer to xenogeneic
      hosts. II. Occurrence of numerous viruslike particles and aberrant melanosomes in
      immunologically conditioned young rats].

PMID- 4347382
TI  - Phenelzine, mood response, and sleep.

PMID- 4347381
TI  - [Ultrastructural changes in Harding-Passey melanoma by transfer to xenogeneic
      hosts. I. Tumour implantation into the anterior eye chamber of rats and guinea
      pigs].

PMID- 4347383
TI  - Cholinergic activation of vestibular neurones leading to rapid eye movements in
      the mesencephalic cat.

PMID- 4347384
TI  - Sphingolipids of mushrooms.

PMID- 4347385
TI  - Temperature-dependent binding of estrogen receptor to chromatin.

PMID- 4347386
TI  - Affinity labeling of Escherichia coli B deoxyribonucleic acid dependent
      ribonucleic acid polymerase.

PMID- 4347387
TI  - A random sequential mechanism for arginyl transfer ribonucleic acid synthetase of
      Escherichia coli.

PMID- 4347388
TI  - [Effects of carcinogenic hydrocarbons on lipids of plasma membranes and
      mitochondria of Saccharomyces cerevisiae].

PMID- 4347389
TI  - Control of lipid metabolism in hepatomas: conversion of glutamate carbon to fatty
      acid carbon via citrate in several transplantable hepatomas.

PMID- 4347390
TI  - Glycerophosphoryl diglucosyl diglyceride, a new phosphoglycolipid from
      Streptococci.

PMID- 4347391
TI  - A facile synthesis of 1-acyl ethylene glycol-2-phosphorylcholines.

PMID- 4347392
TI  - The kinetic properties of very low density lipoprotein triglyceride in type 3
      hyperlipoproteinemia.

PMID- 4347393
TI  - Role of high density lipoproteins in the lecithin-cholesterol acyltransferase
      activity with sonicated lecithin-cholesterol dispersions as substrate.

PMID- 4347394
TI  - [Study of positive regulatory mechanisms at the transcriptional level].

PMID- 4347395
TI  - Molecular forms of enzymes in cancer.

PMID- 4347396
TI  - [Molecular forms of fetal enzymes in hepatoma].

PMID- 4347397
TI  - Glycogen storage diseases.

PMID- 4347398
TI  - [Medical applications and therapeutic prospects deduced from knowledge in
      molecular pathology].

PMID- 4347400
TI  - [Spontaneous paralysis of the anterior interosseous nerve].

PMID- 4347399
TI  - The use of premarin, conjugated estrogens-equine to control. Functional uterine
      bleeding and the urinary estrogen metabolism after administration.

PMID- 4347401
TI  - Levels of cytochromes in heart, liver, kidney and brain in the developing rat.

PMID- 4347402
TI  - Hyperpolarization by cyclic AMP (activation of diphosphoinositide kinase).

PMID- 4347403
TI  - Induction of brain tumours in high yield by administration of N-ethyl-N
      nitrosourea to newborn rats.

PMID- 4347404
TI  - Effect of N 6 O 2 -dibutyryl cyclic 3',5'-adenosine monophosphate on the
      pinocytosis of brain capillaries of mice.

PMID- 4347405
TI  - Interferon production by Sendai virus-treated hamster and monkey cells.

PMID- 4347406
TI  - Compensatory growth of the ovaries, adrenal glands and kidneys in blinded,
      anosmic rats.

PMID- 4347407
TI  - Biological properties of synthetic Ser 4 -Arg 8 -oxytocin (Ile 3 -Ser 4 -arginine
      vasopressin): role of the residue No. 4 in the hormone-pressor receptor
      interaction.

PMID- 4347408
TI  - Plasma NADase in tuberculosis.

PMID- 4347409
TI  - Correlation between changes in antitumor immune parameters and tumor growth in
      vivo in rats.

PMID- 4347411
TI  - Recurrent excitation in the CA3 region of cat hippocampus.

PMID- 4347410
TI  - An analysis of dishabituation and sensitization of the gill-withdrawal reflex in
      Aplysia.

PMID- 4347412
TI  - Diurnal rhythms of sleep in the rat: augmentation of paradoxical sleep following
      alterations of the feeding schedule.

PMID- 4347413
TI  - Synthesis of a fully protected heptacosapeptide norleucine analog corresponding
      to positions 21-47 of the primary structure of staphylococcal nuclease.

PMID- 4347414
TI  - Studies on the coordination of reduced glutathione to B 12  coenzymes.

PMID- 4347416
TI  - LSD and cyanotic congenital heart disease.

PMID- 4347415
TI  - Common peroneal nerve palsy. Evaluation and management.

PMID- 4347417
TI  - Medical beliefs and practices of the Aymara indians.

PMID- 4347418
TI  - The treatment of toxoplasmosis during pregnancy.

PMID- 4347420
TI  - Differential block at high frequency of branches of a single axon innervating two
      muscles.

PMID- 4347419
TI  - Pseudo-fi + I-like sex factors, R62(I), selective for increased pilus synthesis.
AB  - An I-like R factor, R62(I), inhibits F-like pilus synthesis and selects for
      mutant sex factors with a greatly increased capacity for pilus production.

PMID- 4347421
TI  - An electron spin resonance study of nitrosamine anion radicals.

PMID- 4347422
TI  - Transformation of rat liver cells with chicken sarcoma virus B77 and murine
      sarcoma virus.
AB  - Rat liver cells in vitro were transformed with chicken sarcoma virus B77, giving
      RL(B77) cells, and with murine sarcoma virus (Harvey), giving RL(MSV) cells. Rat
      liver cells transformed spontaneously in vitro were designated RL cells. In
      addition, the RL(MSV) cell line was adapted for growth in culture fluid
      containing 25 mug of 5-bromodeoxyuridine per ml. All cell lines were tumorigenic
      in 1-wk-old rats. The number of cells needed for induction of tumor growth was
      1,000-fold higher in the case of RL(B77) cells in comparison with RL(MSV) cells
      and RL cells. No production of viral particles from any of the cell lines
      investigated was detected by plating concentrated supernatant fluid of the
      cultures on different secondary embryo cells with and without fusion by Sendai
      virus, by labeling with uridine-5-(3)H, or by assay for deoxyribonucleic acid
      polymerase activity. The viral genome was rescued by fusion of RL(B77) cells with
      chicken cells. Chicken sarcoma virus rescued from (RL(B77) cells differed in
      plating efficiency on duck cells from B77 virus rescued from transformed rat
      embryo cells. No virus was rescued after fusion of RL(MSV) and RL cells with
      mouse, rat, or chicken embryo cells. Infectious murine sarcoma virus can be
      induced by 5-bromodeoxyuridine from RL(MSV) cells.

PMID- 4347423
TI  - Stimulation of aryl hydrocarbon hydroxylase induction in cell cultures by
      interferon.
AB  - In cell cultures previously treated with homologous interferon, the magnitude of
      antiviral activity and the degree of stimulation of aryl hydrocarbon hydroxylase
      induction appear to be directly related. In a highly purified mouse interferon
      preparation, the factor stimulating hydroxylase induction and the factor
      directing antiviral activity are inactivated by heating to 70 C or by treating
      with trypsin. Also, both activities demonstrate species specificity.

PMID- 4347424
TI  - Extraordinary effects of specific monovalent cations on activation of reovirus
      transcriptase by chymotrypsin in vitro.
AB  - Activation of reovirus transcriptase activity, latent in intact virions, by
      digestion of purified virions with chymotrypsin (CHT) in vitro shows a stringent
      requirement for specific monovalent cations. Cs(+), Rb(+), or K(+) ions are
      capable of facilitating activation by chymotryptic digestion. Na(+), Li(+), or
      NH(4) (+) ions are not capable of facilitating the CHT activation of polymerase
      activity and are antagonistic towards the effects of the facilitating ions. The
      data indicate that the effect of the cations is exerted on activation of the
      polymerase activity by CHT as opposed to an effect on polymerization per se. This
      effect may be important biologically in that it provides a mechanism whereby the
      virion can sense whether it is in an intracellular or an extracellular
      environment and thereby can avoid premature uncoating.

PMID- 4347425
TI  - Characterization of morphologic revertants of murine and avian sarcoma virus
      transformed cells.
AB  - Morphologic revertants which contain avian or murine sarcoma viruses have
      previously been isolated at low frequency from clonal lines of transformed
      mammalian cells. In the present study, these lines have been further
      characterized. They are indistinguishable from nontransformed parent cell lines
      with respect to parameters such as saturation density and colony formation in
      depleted medium or on monolayers of contact-inhibited cells. The rate of glucose
      uptake had also reverted to normal. The malignant potential of one of the
      revertant lines was examined and found to be markedly reduced compared to that of
      the corresponding transformed cells. The differences in the susceptibilities of
      revertant cells to retransformation by the same or other oncogenic viruses
      suggest that different cellular genes may be involved in expression of
      transformation by various tumor viruses.

PMID- 4347426
TI  - Effect of viral double-stranded RNA on protein synthesis in intact cells.
AB  - The addition of purified, noninfectious, double-stranded RNA of bovine
      enterovirus, a picornavirus, to intact cells in culture results in a rapid
      cessation of cellular polypeptide synthesis. This inhibition is specific for host
      cell protein synthesis since the translation of picornavirus-specific proteins is
      not affected by the double-stranded viral RNA.

PMID- 4347427
TI  - Stimulation of Sendai virion transcriptase by polyanions.
AB  - Exogenous polyribonucleotides stimulated the ribonucleic acid (RNA) transcriptase
      in Sendai virions. Added yeast RNA, polyadenylic acid, or polycytidylic acid
      increased incorporation of (3)H-guanosine monophosphate as much as fivefold. The
      products of stimulated reactions were virus-specific as determined by
      hybridization with Sendai virion RNA, but they sedimented more slowly (13s) than
      the product of an unstimulated reaction (16s). The stimulating activity was
      nondialyzable and heat stable, but was abolished by alkaline hydrolysis.
      Nucleoside monophosphates, individually or in combination, were ineffective,
      confirming the requirement for a polymer. Among other substances tested for
      effects on Sendai virion transcriptase, polyaspartic acid and polyglutamic acid
      stimulated the enzyme; polyinosinic acid, polyuridylic acid, and polyamines had
      no effect; and dextran sulfate and polyvinyl sulfate were inhibitory.

PMID- 4347428
TI  - Chromatographic and electrophoretic analysis of viral proteins from hamster and
      chicken cells transformed by Rous sarcoma virus.
AB  - Several methods have been explored for the detection and characterization of
      viral proteins from soluble extracts of cells transformed by Rous sarcoma virus
      (RSV). Viral antigens have been analyzed after gel filtration in several
      solvents. In addition, immune complexes formed with virus-specific sera have been
      isolated by agarose gel filtration and by high- or low-speed centrifugation
      through sucrose solutions. Radioactive proteins from these immune complexes have
      been analyzed by gel filtration in 6 m guanidine hydrochloride or by
      polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate.
      Comparison with proteins from purified virus indicates the presence of two viral
      core proteins (gs1 and gs2) in the soluble fraction from virus-producing chicken
      cells. In the same fraction from RSV-transformed hamster cells (which do not
      produce virus), three gs proteins (gs1, gs2, and gs3) could be identified. The
      soluble viral gs proteins are strongly bound to at least two larger polypeptides
      in cell extracts. These polypeptides do not appear to be viral in origin and have
      the property of undergoing a time-dependent aggregation in the extracts. One of
      these cell-derived proteins, which is present in a variety of uninfected cell
      types, closely resembles actin.

PMID- 4347430
TI  - In vivo conversion of the single-stranded DNA of the kilham rat virus to a double
      stranded form.
AB  - Kilham rat virus (KRV) contains linear, single-stranded DNA in the virion. The
      fate of radioactive viral DNA was followed after infection of monolayer cells.
      Within 60 min after infection of cells, 28 to 42% of the parental viral DNA is
      converted to a new form. This new DNA form is believed to be double stranded and
      linear on the basis of its sedimentation in neutral and alkaline sucrose
      gradients, elution from hydroxyapatite columns, its buoyant density in
      equilibrium CsCl density gradients, and appearance in the electron microscope.
      The double-stranded linear KRV DNA may be analogous to the replicative form of
      certain bacteriophages, including phiX174, which contain single-stranded circular
      genomes.

PMID- 4347429
TI  - Isolation of an infectious ribonucleoprotein from vesicular stomatitis virus
      containing an active RNA transcriptase.
AB  - A ribonucleoprotein complex (TNP) containing an active RNA polymerase was
      isolated from purified vesicular stomatitis virus particles. The TNP sedimented
      through a sucrose gradient as a single band and appeared under the electron
      microscope as discrete long filaments in a spiral configuration. TNP contained
      one major and two minor polypeptides, but not the polypeptides associated with
      the outer coat of vesicular stomatitis virus. BHK-21 clone 13 cells could be
      infected with TNP, yielding infectious virus particles.

PMID- 4347431
TI  - Role of mitochondria in the production of RNA-containing tumor viruses.
AB  - The role of mitochondria in the reproduction of RNA-containing tumor viruses was
      examined by using ethidium bromide (EB) to induce degenerative effects in
      mitochondria. The effects of EB in murine and avian cells were monitored by
      electron microscopy. Chronically infected mouse (JLS-V5) cells, in which
      extensive mitochondrial changes were induced, continued to produce murine
      leukemia virus. Also, complete reproductive cycles of Rous sarcoma virus (RSV)
      occurred in newly infected chicken embryo cells exposed to EB. Morphological
      transformation characteristic of infection of chicken embryo cells by RSV
      occurred in cells which contained induced aberrant mitochondria. The results
      demonstrate that mitochondria play a relatively minor role, if any, in the
      reproduction of RNA-containing tumor viruses.

PMID- 4347432
TI  - Picornaviral gene order: comparison of a rhinovirus with a cardiovirus.
AB  - We describe conditions for unmasking virus-specific protein synthesis in cells
      infected with rhinoviruses 1A and 2. The gene order and cleavage pattern of
      rhinovirus 1A show many similarities to those of encephalomyocarditis virus and
      of poliovirus.

PMID- 4347433
TI  - [Obesity].

PMID- 4347434
TI  - A note on the duration of neutralizing antibody against avian encephalomyelitis
      virus in chickens.

PMID- 4347435
TI  - The fine structure of Marek's disease virus and herpesvirus of turkey in cell
      culture.

PMID- 4347436
TI  - Case records of the Massachusetts General Hospital. Weekly clinicopathological
      exercises. Case 15-1973.

PMID- 4347438
TI  - The possibilities of applying mass miniature radiography for public health care.

PMID- 4347437
TI  - [Ulcerations due to steroid administration].

PMID- 4347439
TI  - The role of mass chest radiography in preventive medicine.

PMID- 4347440
TI  - Conservative mediastinal node dissection for the treatment of carcinoma of the
      breast.

PMID- 4347441
TI  - Experiences with bilateral primary carcinoma of the breast.

PMID- 4347442
TI  - [Pathogenesis and clinical manifestations of intestinal amebiasis].

PMID- 4347443
TI  - Effect of chlorothiazide and sodium on vascular responsiveness to angiotensin II.

PMID- 4347444
TI  - Changes in renin kinetics induced by nephrectomy.

PMID- 4347445
TI  - Effects of ganglionic blocking agents on adrenergic transmission in rat
      mesenteric arteries.

PMID- 4347446
TI  - Hydration changes produced by central infusion of angiotensin II.

PMID- 4347448
TI  - Enterostomal therapy: better care for the ostomy patient.

PMID- 4347447
TI  - Metabolic clearance rate of radioiodinated angiotensin II in normal men.

PMID- 4347449
TI  - [Ultrastructure of endothelial cells in small blood vessels of the rabbit and pig
      following herpesvirus infection].

PMID- 4347450
TI  - [Ultrastructural changes in the lung of pigs following herpesvirus suis
      infection].

PMID- 4347451
TI  - Biochemical and morphological aspects of zinc deficiency in Rhodotorula gracilis.

PMID- 4347453
TI  - Chemical composition of gas vesicles isolated from Anabaena flos-aquae.

PMID- 4347452
TI  - Enzyme induction and repression in Arthrobacter crystallopoietes.

PMID- 4347454
TI  - Regulation of the synthesis of mitochondrial enzymes and cytochromes. Distinction
      between catabolite repression and anaerobiosis in Saccharomyces cerevisiae.

PMID- 4347455
TI  - Impression-expression reactions in cellular pathology.

PMID- 4347456
TI  - Cobaltous ion complex of reduced lipoamide dehydrogenase.

PMID- 4347458
TI  - Glycoproteins associated with nuclei of cells before and after transformation by
      a ribonucleic acid virus.

PMID- 4347457
TI  - On the active site topography of isoleucyl transfer ribonucleic acid synthetase
      of Escherichia coli B.

PMID- 4347460
TI  - [Study of macromolecules and biological particles by ultracentrifugation in
      sodium perchlorate gradient. 1. Physical properties of sodium perchlorate
      solutions and study of the cytoplasmic particles of Hela cells by
      ultracentrifugation in sodium perchlorate gradient].

PMID- 4347459
TI  - Amino acid incorporation and products of protein synthesis in isolated
      chloroplasts of Euglena gracilis.

PMID- 4347461
TI  - [Study of pinocytosis and hydrolysis of thyroglobulin by the normal and
      pathological thyroid cell].

PMID- 4347462
TI  - Hormonal effects on thymidine kinase and thymidylate kinase activity of estrogen
      dependent tumors in the rat.

PMID- 4347463
TI  - Ultrastructural effects of 5-bromodeoxyuridine and 5-fluorouracil in Drosophila.

PMID- 4347464
TI  - Activities and isoenzyme patterns of some enzymes of glucose metabolism in human
      primary malignant hepatoma.

PMID- 4347465
TI  - The carcinogenic potential of aflatoxin or its metabolites in rats from dams fed
      aflatoxin pre- and postpartum.

PMID- 4347466
TI  - Ultrastructural, histological, and biochemical alterations produced by 12-O
      tetradecanoyl-phorbol-13-acetate on mouse epidermis and their relevance to skin
      tumor promotion.

PMID- 4347467
TI  - Inhibition of transfer and ribosomal RNA methylases by polyinosinate.

PMID- 4347468
TI  - Transplantability and biological behavior of mouse liver tumors induced by
      ethylnitrosourea.

PMID- 4347469
TI  - Cyclic adenosine 3',5'-monophosphate phosphodiesterase activity in normal,
      differentiating, regenerating, and neoplastic liver.

PMID- 4347470
TI  - Reversible and irreversible effects of tissue culture on enzyme patterns of
      spontaneous mouse tumors and mouse and human embryo tissues.

PMID- 4347471
TI  - Dihydroorotate dehydrogenase in liver and Morris hepatomas.

PMID- 4347473
TI  - Enhanced responses to tyramine and angiotensin produced by 4,4'-biphenylene bis
      ((2-oxoethylene)-bis-(2,2-diethoxylethyl)dimethylammonium bromide) (DMAE).

PMID- 4347474
TI  - Angiotensin-induced contraction of the cat nictitating membrane.

PMID- 4347475
TI  - Selective release of newly synthesized cardiac norepinephrine induced by
      angiotensin II.

PMID- 4347476
TI  - The effect of a hemicholinium analogue, HC-15, of neuromuscular transmission.

PMID- 4347478
TI  - The physicochemical characteristics and purification of slow-reacting substance
      of anaphylaxis.

PMID- 4347477
TI  - Cellular analysis of immunosuppression to synthetic polypeptide immunogens
      induced by a murine leukemia virus.

PMID- 4347480
TI  - Inactivation of human interferon by urine.

PMID- 4347479
TI  - Variations in complement levels during active and adoptive immunization.

PMID- 4347482
TI  - [Classification of potentials registered on an entire nerve by electronic
      measurement of propagation velocities].

PMID- 4347481
TI  - [Harmonic analysis and energetic study of the spontaneous cerebral electric
      activity in adult rabbits during paradoxical sleep].

PMID- 4347483
TI  - [Electrotonic coupling between the ocular motor neurons of a teleostean fish:
      elective localization at the level of the soma and distinct effects on somatic
      and dendritic functions of these neurons].

PMID- 4347485
TI  - [Influence of the duration of electric stimulation on the ultrastructural
      organization of sympathetic neurons].

PMID- 4347484
TI  - [Effects of denervation and pH changes on conductance to Na+ and K+ of the
      synaptic membrane].

PMID- 4347486
TI  - [Comparative action of metabolic inhibitors and TEA on post-tetanic
      hyperpolarization of the myelinated fiber bundle].

PMID- 4347487
TI  - Twice weekly tuberculosis chemotherapy.

PMID- 4347488
TI  - Synaptic delay and time course of postsynaptic potentials at the junction between
      hair cells and eighth nerve fibers in the goldfish.

PMID- 4347489
TI  - Neonatal sepsis due to clostridium perfringens.

PMID- 4347490
TI  - The hyperlipoproteinemias. Detection, diagnosis, and management.

PMID- 4347491
TI  - Granular cell tumours of the larynx.

PMID- 4347492
TI  - SV40 virus transformation of mouse 3T3 cells does not specifically enhance sugar
      transport.
AB  - The apparent enhancement of 2-deoxy-D-glucose uptake by mouse 3T3 cells
      accompanying transformation by SV40 virus is not due primarily to an effect on
      the transport process but to enhanced phosphorylation of the sugar by
      intracellular kinases. Moreover, the effect is not specifically a function of the
      presence of the viral genome, but is a reflection of the overall growth rate and
      physiological state of the cell.

PMID- 4347493
TI  - [Tracheal stenosis and sterilization of tracheotomy cannulas with ethylene
      oxide].

PMID- 4347494
TI  - [Treatment of myasthenia with corticotropic hormones].

PMID- 4347495
TI  - [Study of the biochemical components and enzymes in the cerebrospinal fluid
      during coma: diagnostic and prognostic value].

PMID- 4347496
TI  - [Anuric complications after perfusion urography in patients with renal failure,
      myeloma excepted].

PMID- 4347497
TI  - [Acute renal failure during the first 3 months of evolution of burns in 315 adult
      patients].

PMID- 4347498
TI  - [Severe generalized arteriospasm after a minimal therapeutic dose of ergotamine].

PMID- 4347499
TI  - [Surgical treatment at the hot phase of fatty embolism. (Apropos of 3 personal
      cases)].

PMID- 4347500
TI  - [Treatment of botulism in a resuscitation unit. 4 years of experience at the
      Centre Anti-Poisons of Marseilles].

PMID- 4347501
TI  - Urethroplasty for anterior urethral stricture.

PMID- 4347502
TI  - The syndrome of hypertension, hyperreninemia and secondary aldosteronism
      associated with renal juxtaglomerular cell tumor (primary reninism).

PMID- 4347503
TI  - The cancer associated antigen test as an index to failure of complete removal of
      urological cancers.

PMID- 4347504
TI  - [Effect of duration of periodate oxidation on the intensity and specificity of
      the PAS-reaction with the regular Schiff reagent and a Schiff-auramin-SO 2  type
      reagent].

PMID- 4347505
TI  - [Cytophysiologic and karyologic characteristics of reticular cell cultures
      sensitive and resistant to the cytopathic effect of enteroviruses].

PMID- 4347506
TI  - Plan and operation of the health and nutrition examination survey. United states-
      1971-1973.

PMID- 4347508
TI  - Increasing antibody titers to herpes simplex virus type 2 during follow-up of
      women with cervical dysplasia.

PMID- 4347507
TI  - [Use of   1 -fetoprotein in the diagnosis of primary liver cell carcinoma].

PMID- 4347509
TI  - Prevalence of antibodies to Epstein-Barr virus, cytomegalovirus and Toxoplasma in
      a Mexican highland community.

PMID- 4347510
TI  - Incidence and etiology of pneumonia, croup and bronchiolitis in preschool
      children belonging to a prepaid medical care group over a four-year period.

PMID- 4347512
TI  - Protamine kinase independent of adenosine 3',5'-monophosphate from rat brain
      cytosol.

PMID- 4347511
TI  - Viral and mycoplasmal pneumonia in a prepaid medical care group during an eight
      year period.

PMID- 4347513
TI  - Cyclic AMP and citric acid accumulation by Aspergillus niger.

PMID- 4347514
TI  - RNase and alkali sensitivity of closed circular mitochondrial DNA of rat ascites
      hepatoma cells.

PMID- 4347515
TI  - Carbon tetrachloride activation in liver microsomes from rats induced with 3
      methylcholantrene.

PMID- 4347516
TI  - Comparative binding of albumin and  -glucuronidase by rat liver microsomes.

PMID- 4347517
TI  - The terminal oxidases of Azotobacter vinelandii.

PMID- 4347519
TI  - The role of cyclic AMP in the phosphorylation of proteins in human erythrocyte
      membranes.

PMID- 4347518
TI  - Differences in the carbon tetrachloride-induced damage to components of the
      smooth and rough endoplasmic reticulum from rat liver.

PMID- 4347520
TI  - UDP-glucose pyrophosphorylase synthesis in myxamoebae of Dictyostelium
      discoideum.

PMID- 4347521
TI  - Studies of the Rous sarcoma virus RNA: characterization of the 5'-terminus.

PMID- 4347522
TI  - 4,4'-Bis dimethylaminodiphenylcarbinol: a new reagent for selective chemical
      modification. Interaction with porcine malate dehydrogenase.

PMID- 4347523
TI  - UDP-glucose dehydrogenase: substrate binding stoichiometry and affinity.

PMID- 4347524
TI  - The effect of inhibitors of RNA and protein synthesis on dibutyryl cyclic AMP
      mediated morphological transformations of Chinese hamster ovary cells in vitro.

PMID- 4347525
TI  - EPR behavior of a soluble cardiac NADH dehydrogenase.

PMID- 4347526
TI  - The primary acid product of DPNH.

PMID- 4347528
TI  - Role of  -NADH for microsomal ethanol oxidation.

PMID- 4347527
TI  - Modification of hamster sperm adenyl cyclase by capacitation in vitro.

PMID- 4347529
TI  - Release and binding of proteins and enzymes with isolated inner mitochondrial
      membranes.

PMID- 4347530
TI  - The kinetics of the cytochrome-c-azurin redox equilibrium.

PMID- 4347531
TI  - Activation of glycogen synthetase and inactivation of phosphorylase kinase by the
      same phosphoprotein phosphatase.

PMID- 4347532
TI  - Charge distribution in electron transport components: cytochrome c and cytochrome
      c oxidase mixtures.

PMID- 4347533
TI  - Acetylcholine stimulates hydrolysis of  32 P-labeled phosphatidic acid in guinea
      pig synaptosomes.

PMID- 4347534
TI  - New poliovirus-related polypeptides in the nucleus-associated fraction of HeLa
      cell cytoplasm.

PMID- 4347535
TI  - [Fractions of 70 S RNA from avian myeloblastosis virus, enriched in rapidly
      hybridizable sequences with cellular DNA and associated with poly A].

PMID- 4347536
TI  - Biosynthesis of the parasporal inclusion of Bacillus thuringiensis: half-life of
      its corresponding messenger RNA.

PMID- 4347537
TI  - Oestradiol "neo nuclear receptor" in the rat uterus: sedimentation constant and
      conditions of formation.

PMID- 4347538
TI  - [Comparative study of transfer ribonucleic acids extracted from rat liver and
      Zajdela hepatoma. I. Study of the acceptor properties of tRNA].

PMID- 4347539
TI  - [Comparative study of transfer ribonucleic acids extracted from rat liver and
      Zajdela hepatoma. 2. Comparison of chromatographic fractionation patterns of
      aminoacyl-tRNA from rat liver and Zajdela hepatoma].

PMID- 4347540
TI  - [Isolation and properties of external and internal membranes of plant
      mitochondria].

PMID- 4347541
TI  - Central pleomorphic adenoma in the mandible: report of a case.

PMID- 4347542
TI  - [Ligation of the hepatic artery. Results of 16 operations for malignant tumors of
      the liver].

PMID- 4347543
TI  - Method for determination of cyclic AMP in plasma.

PMID- 4347544
TI  - Stable reagents for determination of serum triglycerides by a colorimetric
      Hantzsch condensation method.

PMID- 4347546
TI  - Effects of eserine and neostigmine on release of acetylcholine into perfused
      cerebral ventricles of unanaesthetized dogs.

PMID- 4347545
TI  - Specificity of leucine stimulation of insulin release.

PMID- 4347547
TI  - Effect of parainfluenza-3 neuraminidase on bovine nasal secretion.
AB  - Three samples of bovine nasal secretion were each separated into a sol phase and
      a surface gel phase. In all samples, the gel phase contained an approximately
      four times greater amount of bound N-acetylneuraminic acid (NANA) than the sol
      phase. From the gel phase, bound NANA could be released by exposure to
      parainfluenza-3 virus neuraminidase. The surface gel appears to be a natural
      substrate for this enzyme.

PMID- 4347548
TI  - Semisynthetic  -lactam antibiotics. 1. Acylation of 6-aminopenicillanic acid with
      activated derivatives of  -sulfophenylacetic acid.

PMID- 4347549
TI  - Antimetabolites of coenzyme Q. 17. Improved synthesis of 5-hydroxy-1,4
      benzoquinone analogs and their indices.

PMID- 4347550
TI  - Design, synthesis, and broad spectrum antiviral activity of 1- -D-ribofuranosyl
      1,2,4-triazole-3-carboxamide and related nucleosides.

PMID- 4347551
TI  - Potential antitumor agents. 6. Possible irreversible inhibitors of ribonucleoside
      diphosphate reductase.

PMID- 4347552
TI  - Potential antifertility agents. 2. Tetrazole derivatives of nonsteroidal
      estrogens.

PMID- 4347553
TI  - Interplay of vasodilator and vasoconstrictor substances in the femoral arterial
      bed: identification of the angiotensin cofactor.

PMID- 4347554
TI  - Effect of AY-9944, a cholesterol biosynthesis inhibitor, on fetal lung
      development and on the development of type II alveolar epithelial cells.

PMID- 4347555
TI  - Alterations of rat liver lysosomes and smooth endoplasmic reticulum induced by
      the diazafluoranthen derivative AC-3579. I. Morphologic and biochemical lesions.

PMID- 4347556
TI  - [Radioimmunological detection of angiotensin I and II for functional diagnostics
      of the renin-angiotensin system in various types of hypertension].

PMID- 4347557
TI  - [Gonadotropin releasing effect of synthetic LH releasing hormone].

PMID- 4347558
TI  - What's your diagnosis? Adenocystic carcinoma.

PMID- 4347559
TI  - [Further studies on the influence of the salivary glands on adrenal cortex
      activity].

PMID- 4347561
TI  - Amnesia, consolidation, and retrieval.

PMID- 4347560
TI  - [Depression of lipolysis and potentiation of the hypoglycemic effect of insulin
      using insulin derivatives with a neutral effect on the blood sugar level].

PMID- 4347562
TI  - [Radiation therapy of cerebral tumours].

PMID- 4347563
TI  - [Diabetic peripheral neuropathy. Anatomoclinical study with ultrastructure of a
      nerve biopsy].

PMID- 4347564
TI  - [Peripheral neuropathies caused by disulfiram (antabuse)].

PMID- 4347565
TI  - Purine overproduction in man associated with increased
      phosphoribosylpyrophosphate synthetase activity.
AB  - In hemolyzates from red cells of two brothers with purine overproduction and
      gout, activity of phosphoribosylpyrophosphate synthetase is more than twofold
      greater than that measured in normal or other gouty individuals. The increased
      enzyme activity, which is also demonstrable in fibroblasts of the one patient
      tested, is associated with increased production of 5-phosphoribosyl-1
      pyrophosphate by intact cells, an indication that the enzyme abnormality is the
      basis for the purine overproduction. This genetic abnormality is an example of an
      increased enzyme activity producing a disease state.

PMID- 4347566
TI  - Metabolism of glucose in the human endometrium with special reference to
      fertility and contraception.

PMID- 4347567
TI  - Fibrin degradation products during postoperative radiotherapy of ovarian
      carcinoma.

PMID- 4347568
TI  - The number of glomerular cells and substructures in early juvenile diabetes. A
      quantitative electron microscopic study.

PMID- 4347569
TI  - Metastases to the uterus. Five cases diagnosed on the basis of curettings.

PMID- 4347570
TI  - Sexual precocity attributable to ectopic gonadotropin secretion by
      hepatoblastoma.

PMID- 4347571
TI  - The possible role of the carotid bodies as chemoreceptors in the laryngeal
      reflex.

PMID- 4347573
TI  - [Study of macromolecules and biological particles by density gradient
      ultracentrifugation with sodium perchlorate. II. Calculation to interpret
      experimental results or for simulation experiments].

PMID- 4347572
TI  - [Demonstration and separation of the protein components of human serum alpha
      lipoproteins].

PMID- 4347574
TI  - [Osmotic behavior of the myeloid bodies of the retinal pigmented epithelium].

PMID- 4347575
TI  - [Preliminary observations on the mechanism of action of somatostatin, a
      hypothalamic factor inhibiting the secretion of growth hormone].

PMID- 4347576
TI  - [Sulfatides of plasma and erythrocytes].

PMID- 4347577
TI  - [Cylindroma of the epiglottis].

PMID- 4347578
TI  - On a collagenase-like enzyme detected in the extracts of hypothalamus and
      hypophysis.

PMID- 4347579
TI  - Composition of low density lipoprotein in children with familial
      hyperbetalipoproteinaemia and the effect of treatment.

PMID- 4347580
TI  - A reproducible quantitative collagenase radiofibril assay.

PMID- 4347581
TI  - Electroimmunodiffusion of   2 M, IgA and IgM in nanogram quantities with a
      hydroxyethylcellulose-agarose gel: application to unconcentrated CSF.

PMID- 4347582
TI  - Regulatory processes in the maturation and early cleavage of amphibian eggs.

PMID- 4347583
TI  - Studies on the human glomerular basement membrane. Composition, nature of the
      carbohydrate units and chemical changes in diabetes mellitus.

PMID- 4347584
TI  - Pitfalls in the diagnosis of amebic colitis.

PMID- 4347585
TI  - Paget's disease of the anus secondary to a malignant papillary adenoma of the
      rectum.

PMID- 4347586
TI  - [Allergic reactions of the lungs caused by drugs].

PMID- 4347587
TI  - [The morphology of so-called bronchial wall diverticula in bronchograms in
      chronic bronchitis].

PMID- 4347589
TI  - Dynamics of axial ligation in metalloporphyrins. II.  Porphyrin "inversion" and
      halogen exchange in high-spin iron complexes.

PMID- 4347588
TI  - Sensitivity of the electron spin resonance technique as applied in histochemical
      research on normal and pathological calcified tissues.

PMID- 4347590
TI  - Electron spin resonance of (25 Mg)chlorophyll a.

PMID- 4347591
TI  - The future for medical education and women in medicine.

PMID- 4347592
TI  - Rehabilitation medicine as an art form.

PMID- 4347593
TI  - Medical education. One step at a time.

PMID- 4347594
TI  - The radiologic aspects of toxoplasmosis.

PMID- 4347595
TI  - Radioimmunoassay of mammalian type C viral proteins. 3. Detection of viral
      antigen in normal murine cells and tissues.
AB  - A radioimmunoassay specific for a murine leukemia virus structural protein, the
      gs antigen, detects an antigenic reactivity in normal murine cells in culture and
      natural tissues. The assay was shown to measure an antigen that is highly related
      to the virion protein as shown by absorption tests, immunoadsorbent
      chromatography, and by analysis of linearized dose-response curves. These
      findings combined with the finding of viral-specific RNA indicate that portions
      of the viral genome are being expressed with a much greater frequency than
      previously appreciated.

PMID- 4347596
TI  - Prevention of cell-to-cell spread of herpes simplex virus by leukocytes.
AB  - Antibody to herpes simplex virus (HSV) plus complement destroyed HSV-infected
      cells but did not stop the spread of the infection. Studies on the relationship
      between the time of appearance of viral antigens on the cell surface,
      immunological destruction of the cells by antiviral antibody and complement, and
      transfer of the virus to adjacent cells showed that the virus spread from
      infected to uninfected cells before the infected cells were susceptible to
      immunological destruction. Incubation of infected monolayers with leukocytes,
      however, stopped the spread of the virus by nonspecifically damaging both
      infected and uninfected cells and by presumably breaking intercellular bridges.
      When leukocytes were removed from infected monolayers, viral plaques developed.
      If, however, antiviral antibody and complement were added to monolayers before
      the leukocytes were removed, the development of plaques was prevented. These
      findings suggest that both antibody and leukocytes are needed to cure HSV
      infections.

PMID- 4347598
TI  - Accelerated hypertension secondary to oral contraceptives.

PMID- 4347599
TI  - [Biochemical studies on human salivary proteins. XI. Effect of saliva-parotin-A
      on phosphatase activities].

PMID- 4347597
TI  - Immunologic rejection of diethylnitrosamine-induced hepatomas in strain 2 guinea
      pigs: participation of basophilic leukocytes and macrophage aggregates.
AB  - The morphologic events associated with the immunologic rejection by strain 2
      guinea pigs of ascites variants of two lines of diethylnitrosamine-induced tumors
      have been studied by light and electron microscopy. Tumor injection sites in the
      skin of control animals exhibited clusters of viable, actively mitotic tumor
      cells along with a modest inflammatory infiltrate composed of lymphocytes,
      macrophages, neutrophils, and rare basophils. In contrast, similar injections of
      either tumor line in specifically sensitized guinea pigs elicited typical delayed
      type skin reactions associated with tumor cell necrosis and a more extensive
      inflammatory infiltrate including a selective increase in the number of
      basophilic leukocytes (12%, line 1, or 23%, line 10, of total inflammatory
      cells). That basophils may have a role in tumor resistance in vivo is suggested
      by the close anatomic associations observed between basophils and tumor cells,
      and by the fact that basophils were the only inflammatory cell to demonstrate a
      relative increase in frequency in the lesions of sensitized as compared with
      control animals. Moreover, intraperitoneal injection of line 1 tumor in
      specifically sensitized animals elicited a striking basophilia within 24 h.
      Unlike macrophages, basophils did not phagocytose tumor cells but did evidence
      occasional extrusion of granules and frequently exhibited loss of granule
      staining density, a change that may be related to release of mediator substances.
      Electron microscope studies of line 1 tumor rejection in the peritoneal cavities
      of specifically sensitized guinea pigs demonstrated aggregations of "activated"
      macrophages, lymphocytes, basophils, and damaged or dead tumor cells. These
      aggregates, held together by complex interdigitations of macrophage villi,
      closely resembled those occurring in vitro among peritoneal exudate cells whose
      migration from capillary tubes was inhibited by migration inhibition factor
      (MIF). Moreover, cells in these aggregates, as well as macrophages inhibited by
      MIF in vitro, lacked a normal coating of cell surface material.

PMID- 4347600
TI  - [Biochemical studies on human salivary proteins. XII. Comparison between saliva
      parotin-A and various hormones on hypocalcemic and acid phosphatase-depressing
      activities].

PMID- 4347601
TI  - [Pituitary tumors and Cushing's syndrome].

PMID- 4347602
TI  - [Ideas concerning cancer].

PMID- 4347604
TI  - Bone as a target organ: toward a better definition of osteoporosis.

PMID- 4347603
TI  - [Hydantoins and neurologic complications].

PMID- 4347605
TI  - Distribution of tritiated human chorionic gonadotropin in superovulated rat
      ovary.

PMID- 4347606
TI  - Cyclic 3',5'-AMP phosphodiesterase activity during cyclic AMP-induced
      differentiation of neuroblastoma cells in culture.

PMID- 4347608
TI  - Microheterogeneity of N-acetyl- -D-hexosaminidase of bull epididymis.

PMID- 4347607
TI  - Differentiation of a myocardial depressant factor present in shock plasma from
      known plasma peptides and salts.

PMID- 4347609
TI  - Interferon induced by endotoxin and Newcastle disease virus in rabbit macrophage
      and kidney cell cultures.

PMID- 4347610
TI  - Interaction of prostaglandin E 1  and angiotensin II on centrally mediated
      pressor activities in the cat.

PMID- 4347611
TI  - Biochemical events in murine cytomegalovirus-infected mouse liver.

PMID- 4347612
TI  - Renal medullary adenylate cyclase in drug-induced nephrogenic diabetes insipidus.

PMID- 4347613
TI  - [Advances in internal medicine].

PMID- 4347614
TI  - [Indications, possibilities and limits of corticostimulation in current
      practice].

PMID- 4347615
TI  - [Lymphoblastic transformation test with Bedsonia antigens (Bedsonia LTT). Its
      nosologic and diagnostic value in Fiessinger-Leroy-Reiter syndrome].

PMID- 4347616
TI  - [The evolution of vitamin-resistant rickets in adults. Apropos of a sporadic
      case].

PMID- 4347617
TI  - Alpha-ecdysone and 20-hydroxyecdysone from frass of the tobacco hornworm, Manduca
      sexta (L.).

PMID- 4347618
TI  - Characterization of the metabolites of vitamin D 3  in the chick.

PMID- 4347619
TI  - [Rare case of damage of the ophthalmic and oculomotor nerves during zoster].

PMID- 4347620
TI  - Biochemistry of the hydroxyprolines.

PMID- 4347621
TI  - Parainfluenza virus Sendai infection in macrophages, ependyma, choroid plexus,
      vascular endothelium and respiratory tract of mice.
AB  - Immunofluorescent observations showed that after intranasal instillation of
      parainfluenza 1 (Sendai) virus into adult mice, infection is confined to the
      epithelial lining of the larger airways. Alveolar macrophages were not
      significantly involved, although they could be infected in vitro. In suckling
      mice, the infection was more acutely lethal and extended into the terminal air
      spaces. The intranasal susceptibility of adult mice was not reproducibly affected
      by treatment with potent antithymocyte serum, and there were no obvious
      pathogenic effects when heterologous antiserum was instilled intranasally into
      infected mice. Peritoneal macrophages were infected by intraperitoneally injected
      Sendai virus, with production of a highly viscous peritoneal exudate. Kupffer
      cells of the liver and endothelial cells in large veins and auricles were
      infected by intravenously injected virus. When injected intracerebrally, Sendai
      virus infected ependyma and choroid plexus epithelium. Adult mice often survived,
      in spite of ependymal destruction and changes in ventricular morphology.
      Astrocytes were activated but not infected.

PMID- 4347623
TI  - [Pecularities of placental barrier permeability and distribution of ristomycin
      sulfate in the blood and organs of albino mice under conditions of sensitization
      with homoplacental protein].

PMID- 4347624
TI  - [Levels of florimycin in tissues of healthy mice following administration by
      various routes].

PMID- 4347622
TI  - The Hermansky-Pudlak syndrome: ultrastructure of bone marrow macrophages.
AB  - The present investigation has explored the fine structure of the lipid inclusions
      which fill the bone marrow macrophages of patients with the Hermansky-Pudlak
      syndrome. Red blood cells are the major substrate of the reticular macrophages,
      and incomplete digestion of erythrocytes leads to formation of the massive
      inclusions. Progressive transformation of the macrophages results in an end-stage
      cell whose damaged cytoplasm is nearly replaced by huge lipid-containing vacuoles
      surrounded by particulate debris. This type of cell has not been found in bone
      marrows from patients with hemolytic, thrombocytopenic or lipid storage diseases.

PMID- 4347625
TI  - Action of quinacrine mustard on polynucleotides.

PMID- 4347626
TI  - Studies in bioluminescence. VII. Bacterial NADH: flavin mononucleotide
      oxidoreductase.

PMID- 4347627
TI  - Inhibition by sulfonamides of the photoreductive step in spinach chloroplast
      photosynthesis.

PMID- 4347628
TI  - [Do serum lipoproteins have esterase activity? II. Study of high density
      lipoprotein of human serum].

PMID- 4347629
TI  - Familial recurrent polyneuropathy. A family and a survey.

PMID- 4347630
TI  - Aspects of subcortical organization of feeding revealed by hypothalamic
      disconnexions in Macaca mulatta.

PMID- 4347631
TI  - Proteolytic activity of a small variety of Entamoeba histolytica. II. Detection
      of enzyme and effect of pH on its activity.

PMID- 4347632
TI  - Cytomegalovirus syndrome post-renal transplantation. Treatment with cytosine
      arabinoside.

PMID- 4347633
TI  - Thecoma in pregnancy.
AB  - A description is briefly given of a patient whose pregnancy was complicated by an
      ovarian thecoma which ruptured spontaneously.Eleven previously reported instances
      of the combination of thecoma and pregnancy are summarized.Although the present
      case appears to be the first in which the mother has survived rupture of the
      tumour, in view of the result to the child this can hardly be claimed as a
      triumph of obstetrics.

PMID- 4347634
TI  - [Metabolism of glucocorticoids--in relation to increased anti-inflammatory
      activity].

PMID- 4347635
TI  - [HCG-receptor of the ovary].

PMID- 4347636
TI  - Hypersomnia in manic-depressive disease (a preliminary report).

PMID- 4347637
TI  - Mechanism of acupunctural anesthesia. The two-gate control theory.

PMID- 4347638
TI  - Clinical neuropathological conference.

PMID- 4347639
TI  - [Enzyme-histochemical studies on the small-intestine mucosa before and during
      carbohydrate absorption].

PMID- 4347640
TI  - [Data on hepatitis antigen (HAA)].

PMID- 4347641
TI  - [Calcification of the stomach in mucinous cell carcinoma].

PMID- 4347642
TI  - [Health characteristics of zinc silicate anticorrosion linings for water storage
      vessels].

PMID- 4347643
TI  - [Nummular and microbial eczema].

PMID- 4347644
TI  - Separation of methylated bases of ribonucleic acid by two-dimensional thin-layer
      chromatography.

PMID- 4347645
TI  - [Thin-layer chromatography of nucleosides].

PMID- 4347646
TI  - Liquid chromatographic analysis of nucleosides, purine base-modified adenosine
      derivatives and 3',5'-cyclic AMP.

PMID- 4347647
TI  - Increased mycoplasma-cell association in transformed human amnion cells.

PMID- 4347648
TI  - Failure of cytarabine in varicella-zoster infections.

PMID- 4347649
TI  - Herpetic chancre.

PMID- 4347650
TI  - Treatment of labial herpes.

PMID- 4347651
TI  - Metoposcopy and kindred arts.

PMID- 4347652
TI  - [Histopathological and prognostic considerations in 14 mixed tumors of the
      salivary glands].

PMID- 4347653
TI  - The exotic animal problem.

PMID- 4347654
TI  - The ventromedial hypothalamus and aggressive behaviors.

PMID- 4347655
TI  - A comparison of the motivational properties of thirst induced by intracranial
      angiotensin and by water deprivation.

PMID- 4347657
TI  - Depression of the H-reflex during tooth grinding in sleep.

PMID- 4347656
TI  - Modulation of visual cortex inhibition during reticular evoked arousal.

PMID- 4347658
TI  - Subcutaneous mastectomy for central tumors of the breast, with immediate
      reconstruction.

PMID- 4347659
TI  - Disseminated cytomegalovirus infection associated with death in a patient with
      severe facial injuries. Case report.

PMID- 4347661
TI  - [Preliminary observations on the behavior of glial cells in culture in the
      presence of noradrenaline, serotonin and the MM neurotropic virus].

PMID- 4347662
TI  - [Biological properties of HeLa cells serially cultivated in hypertonic medium and
      their susceptibility to enteroviruses. I. Biological characteristics of HeLa
      cells serially cultivated in hypertonic growth medium].

PMID- 4347660
TI  - [Action of ionizing radiations on hepatic glucose-6-phosphate dehydrogenase,
      glucose-6-phosphatase and lactic dehydrogenase in mice].

PMID- 4347663
TI  - [Biological properties of HeLa cells serially cultivated in hypertonic medium and
      their susceptibility to enteroviruses. II. Susceptibility of the cells to
      polioviruses and influences of hypertonic maintenance medium on virus
      reproduction and cytopathic effect].

PMID- 4347666
TI  - Calcium metabolism in pancreatic disease.

PMID- 4347665
TI  - The role of pancreatic enzymes in digestion.

PMID- 4347664
TI  - Nutrition, metabolism, and blood lipids in humans with type II A 
      hyperlipoproteinemia.

PMID- 4347667
TI  - Papio cynocephalus age determination.

PMID- 4347668
TI  - Noradrenergic control of circadian rhythms in Cebus albifrons.

PMID- 4347669
TI  - Lead poisoning in zoo-dwelling primates.

PMID- 4347671
TI  - Herpesvirus simiae infection in Macaca radiata.

PMID- 4347670
TI  - Tumors in nonhuman primates: observations during a six-year period in the Yerkes
      primate center colony.

PMID- 4347672
TI  - Infectious diseases in primates--introduction and bibliography.

PMID- 4347673
TI  - Infectious diseases of primates related to capture and transportation.

PMID- 4347674
TI  - The role of H 2 O 2  generation in perfused rat liver and the reaction of
      catalase compound I and hydrogen donors.

PMID- 4347675
TI  - The essential role of the imidazole group of glucagon in its biological function.

PMID- 4347676
TI  - The reaction between indole 3-acetic acid and horseradish peroxidase.

PMID- 4347677
TI  - Pyridine nucleotide biosynthesis in Claviceps.

PMID- 4347679
TI  - Isolated adrenal cortex cells: ACTH agonists, partial agonists, antagonists;
      cyclic AMP and corticosterone production.

PMID- 4347678
TI  - Cytochrome c interaction with membranes. I. Use of a fluorescent chromophore in
      the study of cytochrome c interaction with artificial and mitochondrial
      membranes.

PMID- 4347680
TI  - Adenylate cyclase from guinea pig lung: further characterization and inhibitory
      effects of substrate analogs and cyclic nucleotides.

PMID- 4347681
TI  - Regulation of glycogen metabolism in the adrenal gland. IV. The effect of insulin
      on glycogen synthetase, phosphorylase, and related metabolites.

PMID- 4347682
TI  - Some regulatory properties of glycogen phosphorylase from Streptococcus
      salivarius.

PMID- 4347683
TI  - Stimulation of the (Na +  + K + )-dependent adenosine triphosphatase by amino
      acids and phosphatidylserine: chelation of trace metal inhibitors.

PMID- 4347684
TI  - The effects of adenine nucleotides on NADH binding to mitochondrial malate
      dehydrogenase.

PMID- 4347685
TI  - Role of mitochondria in the sex-directed flocculation of a fission yeast.

PMID- 4347687
TI  - Proteins of the thermophilic fungus Humicola lanuginosa. II. Some physicochemical
      properties of a cytochrome c.

PMID- 4347686
TI  - The effect of dibutyryl adenosine 3':5'-cyclic monophosphate on the synthesis of
      glycolipids by normal and transformed Nil cells.

PMID- 4347688
TI  - Initiation of protein synthesis in vivo in poliovirus-infected HeLa cells.

PMID- 4347689
TI  - Substrate inhibition of soluble and bound lactate dehydrogenase (isoenzyme 5).

PMID- 4347690
TI  - Effects of nucleotides and Na +  on ouabain activation of the phosphatase
      associated with Na + , K + -ATPase.

PMID- 4347691
TI  - Phospholipase C purification and specificity with respect to individual
      phospholipids and brain microsomal membrane phospholipids.

PMID- 4347692
TI  - Ro le of phospholipids in the NA + ,K + -stimulated adenosine triphosphatase
      system of brain microsomes.

PMID- 4347693
TI  - Ultraviolet sensitivity of helper function of murine leukemia virus.

PMID- 4347694
TI  - The nature and treatment of skin conditions observed in horses in Queensland.

PMID- 4347695
TI  - Isolation of a herpesvirus from a pigeon.

PMID- 4347697
TI  - Zonal diffusion, a new technique. Application to the determination of the
      molecular weight of M13 viral deoxyribonucleic acid.

PMID- 4347696
TI  - Redox interactions between cytochrome components and transition ions and metals.

PMID- 4347698
TI  - Electron paramagnetic resonance studies on cobalamin-dependent ribonucleotide
      reduction.

PMID- 4347699
TI  - Separation of phospholipids from glucose-6-phosphatase by gel chromatography.
      Specificity of phospholipid reactivation.

PMID- 4347700
TI  - Guanine phosphoribosyltransferase from Escherichia coli, specificity and
      properties.

PMID- 4347701
TI  - Kinetics and equilibria in partially reduced flavine solutions.

PMID- 4347702
TI  - States of hemoglobin in solution.

PMID- 4347703
TI  - Occurrence and properties of a chromatin-associated F1-histone phosphokinase in
      mitotic Chinese hamster cells.

PMID- 4347704
TI  - Direct incorporation of fatty acids into the halosulfatides of Ochromonas danica.

PMID- 4347705
TI  - Isolation and fractionation of yeast nucleic acids. I. Characterization of poly(L
      lysine) kieselguhr chromatography using yeast nucleic acids.

PMID- 4347706
TI  - Isolation and fractionation of yeast nucleic acids. II. Rapid isolation of
      mitochondrial deoxyribonucleic acid by poly(L-lysine) kieselguhr chromatography.

PMID- 4347708
TI  - Actions of the selective inhibitor of cholinesterase tetramonoisopropyl
      pyrophosphortetramide on the rat phrenic nerve-diaphragm preparation.
AB  - 1. Tetramonoisopropyl pyrophosphortetramide (iso-OMPA) added for 15 min to the
      rat isolated phrenic nerve-diaphragm in a concentration of 30 muM, produced a
      complete selective and stable inhibition of cholinesterase. A concentration of 3
      muM produced near complete inhibition of cholinesterase, and a concentration of
      300 muM also inhibited acetylcholinesterase marginally.2. Inhibition of
      cholinesterase was associated with a sustained increase in the neuromuscular
      blocking action of exogenous butyrylcholine but not of exogenous acetylcholine.
      Iso-OMPA, 300 muM, in addition caused transient increases in the sensitivity of
      the rat diaphragm to exogenous acetylcholine and butyrylcholine. In the same
      concentration, it had a curare-like action on the frog rectus abdominis muscle
      preparation.3. Iso-OMPA, 30 muM, caused reversible increases in the amplitude of
      the twitch response and tetanic responses, which were of a similar magnitude in
      the indirectly stimulated preparation and the directly stimulated curarized
      preparation. Caffeine had a similar effect on the twitch response and its
      effectiveness was increased by iso-OMPA, and vice-versa. Amongst
      anticholinesterases, octamethyl pyrophosphortetramide and tetraethylpyrophosphate
      also enhanced the amplitude of the tetanic response, but paraoxon, dyflos, and
      mipafox did not.4. It is concluded that iso-OMPA, in concentrations (3 and 30
      muM) which in 15 min give near maximal or maximal selective inhibition of
      cholinesterase, has no effect on the transmission of nerve impulses at the
      neuromuscular junction, but enhances reversibly the amplitude of the contractile
      response to stimulation by a direct action upon the muscle fibre, which involves
      a mechanism related to but not identical with that by which caffeine potentiates
      twitch tension. In higher concentrations, iso-OMPA has a curare-like action at
      the neuromuscular junction.

PMID- 4347707
TI  - Effects of catecholamines and adenosine derivatives given into the brain of
      fowls.
AB  - 1. Adult fowls (Gallus domesticus) with cannulae chronically implanted into the
      IIIrd cerebral ventricle and various other sites of the brain received
      microinfusions or injections of catecholamines, adenosine, 3',5'-cyclic AMP or
      its dibutyryl derivative. The effects of these substances on behaviour,
      electrocortical activity and body temperature were studied.2. Behavioural and
      electrocortical sleep with fall in body temperature were obtained with
      intraventricular noradrenaline, alpha-methylnoradrenaline and isoprenaline;
      dopamine was ineffective. The doses required to elicit sleep were smaller than
      those affecting body temperature. Following mebanazine, the effects of
      noradrenaline were prolonged and doses of dopamine, previously ineffective,
      lowered body temperature and induced behavioural and electrocortical sleep.3.
      Noradrenaline, alpha-methylnoradrenaline, isoprenaline and dopamine infused into
      the hypothalamus induced sleep and lowered body temperature. Effective doses of
      noradrenaline, alpha-methylnoradrenaline and isoprenaline infused into the
      hypothalamus were one-twentieth to one-fifth those for intraventricular
      injection. Tachypnoea developed with isoprenaline and dopamine. Additionally with
      dopamine, there was deviation of the head to the contralateral side, together
      with repetitive jerking movements of the head. These effects were prolonged and
      intensified by mebanazine, whereas the involuntary movements with dopamine were
      greatly reduced by haloperidol.4. Involuntary movements, but without sleep, were
      induced by infusing dopamine into the paleostriatum augmentatum; noradrenaline
      infused into this site was ineffective.5. In three of five fowls pretreated with
      aminophylline, 3',5'-cyclic AMP infused into the hypothalamus induced behavioural
      and electrocortical sleep; without aminophylline pretreatment, 3',5'-cyclic AMP
      was ineffective. Adenosine infused into the hypothalamus, following pretreatment
      of fowls with aminophylline, consistently induced behavioural and electrocortical
      sleep. Dibutyryl cyclic AMP infused into the hypothalamus of intact fowls
      elicited behavioural arousal, followed by bursts of electrocortical spikes (6 Hz)
      over both cerebral hemispheres, spikes subsequently becoming regular at 1 Hz.
      Clonic limb and body movements occasionally accompanied the bursts of spike
      activity, infrequently developing into convulsions. In fowl encephale isole
      preparations, in which dibutyryl cyclic AMP was infused into the hypothalamus,
      spike activity was confined to the ipsilateral hemisphere.

PMID- 4347709
TI  - [Steroid diagnosis of adrenal cortex disorders. II. Corticotropin, metopirone and
      dexamethasone function test].

PMID- 4347710
TI  - Effect of fast-growing transplantable hepatoma on cell proliferation in host
      tissue of the mouse.

PMID- 4347711
TI  - Isozyme patterns of branched-chain amino acid transaminase in cultured rat
      hepatocytes.

PMID- 4347712
TI  - Effect of p-hydroxyacetanilide on liver cancer induction by N hydroxy-N-2
      fluorenylacetamide.

PMID- 4347713
TI  - Rapid uptake of dietary cholesterol by hyperplastic liver nodules and primary
      hepatomas.

PMID- 4347714
TI  - Transport and metabolism of glucosamine by cultured Novikoff rat hepatoma cells
      and effects on nucleotide pools.

PMID- 4347716
TI  - Estimation of the association constant of the estrogen-receptor complex in human
      breast cancer.

PMID- 4347715
TI  - Tumor-specific transplantation antigens in reticulum cell sarcomas and lymphomas
      induced by the friend virus complex.

PMID- 4347717
TI  - In vivo effects of proteases on cell surface architecture and cell proliferation
      in the liver.

PMID- 4347718
TI  - 1'-Hydroxysafrole, a proximate carcinogenic metabolite of safrole in the rat and
      mouse.

PMID- 4347719
TI  - Demonstration of common sarcoma-associated antigen(s) in an established human
      neurogenic sarcoma cell line.

PMID- 4347721
TI  - The establishment of MDMS-resistant cloned cell lines from in vitro cultured,
      MDMS-sensitive, Yoshida sarcoma cells.

PMID- 4347720
TI  - Enhancement of viral oncogenicity by the prior administration of dimethyl
      sulfoxide.

PMID- 4347722
TI  - The effects of chemical irritants and tobacco smoke condensate on the
      chorioallantoic membrane of the fertile hen's egg.

PMID- 4347723
TI  - Guidelines for the control of equine viral infections.

PMID- 4347724
TI  - Fluid secretory response of bovine Thiry jejunal fistula to enterotoxin of
      Clostridium perfringens.
AB  - The effect of enterotoxin of Clostridium perfringens type A was studied in Thiry
      fistula of the bovine jejunum. Accumulation of fluid as a pathological response
      was demonstrable within 30 min after introduction of enterotoxin into the
      fistula; the fluid volume increased rapidly within the first 2 hr and reached
      maximum in 7 hr. The enterotoxin was not destroyed by the jejunal fluid; 52% of
      it was absorbed in 2 to 3 hr, and all of the enterotoxin was taken up within 8 hr
      postinoculation. The accumulation of fluid by the fistula after 0.5 to 2 hr of
      exposure to enterotoxin ceased completely within 5 hr.

PMID- 4347726
TI  - The inhibitory action of  -aminobutyric acid, a probable synaptic transmitter.

PMID- 4347725
TI  - Comparative densities of hydrolase-containing granules from normal and BCG
      induced alveolar macrophages.
AB  - Compared to cells from normal rabbit lungs, BCG-induced alveolar macrophages have
      a marked increase in hydrolase levels and the number of large electron-dense
      subcellular structures. This study was performed to investigate the possibility
      that these electron-dense structures were responsible for the increased hydrolase
      levels of these cells. Using sucrose gradient centrifugation, nuclei-free
      homogenates of normal and BCG-induced macrophages were analyzed with respect to
      the subcellular particles they contain. Gradient fractions were assayed for
      enzymes commonly associated with lysosomes as well as the mitochondrial
      cytochrome oxidase. Fractions of peak hydrolase activity from the BCG-induced
      preparations were consistently more dense than those from the normal cell
      preparations. Ultrastructural studies of the particulate material found in
      fractions of peak hydrolase activity from BCG-induced preparations revealed the
      presence of electron-dense, often dumbbell-shaped, granules. The data suggest
      that these peculiar granules are responsible for the elevated hydrolase levels of
      BCG-induced alveolar macrophages.

PMID- 4347727
TI  - Projection of forelimb group I muscle afferents to the cat cerebral cortex.

PMID- 4347728
TI  - Physiological pathways through the vestibular nuclei.

PMID- 4347730
TI  - Purification and properties of  -lactamase of pseudomonas aeruginosa.

PMID- 4347729
TI  - Tetrodotoxin, saxitoxin, and related substances: their applications in
      neurobiology.

PMID- 4347731
TI  - Whooping cough in northern Israel.

PMID- 4347733
TI  - Proton nuclear magnetic resonance and electron spin resonance investigation of
      axial solvation in planar, low-spin cobalt(II) porphyrin complexes.

PMID- 4347732
TI  - Proton nuclear magnetic resonance and electron spin resonance investigation of
      the electronic structure and magnetic properties of synthetic low-spin ferric
      porphyrins.

PMID- 4347734
TI  - Conformation of angiotensin II in aqueous solution. Evidence for the  -turn
      model.

PMID- 4347735
TI  - Synthesis and secretion of growth hormone in the rat anterior pituitary. II.
      Properties of the isolated growth hormone storage granules.

PMID- 4347736
TI  - Kinetics of unfolding and refolding of proteins. II. Results for cytochrome c.

PMID- 4347738
TI  - DNA replication of SV40-infected cells. VII. Formation of SV40 catenated and
      circular dimers.

PMID- 4347737
TI  - Kinetics of unfolding and refolding of proteins. 3. Results for lysozyme.

PMID- 4347739
TI  - Nucleotide sequences from messenger RNA transcribed from the operator-proximal
      portion of the tryptophan operon of Escherichia coli.

PMID- 4347740
TI  - Characterization of Simian virus 40 DNA component II during viral DNA
      replication.

PMID- 4347741
TI  - The effect of low concentrations of L-glutamate and L-aspartate on transmitter
      release at the locust excitatory nerve-muscle synapse.

PMID- 4347743
TI  - The modification of bulbo-spinal facilitation of the monosynaptic reflex by 5
      hydroxytryptamine precursors and antagonists.

PMID- 4347742
TI  - The cerebellum as a computer: patterns in space and time.

PMID- 4347744
TI  - Estimation of primary sequence homology from amino acid composition of
      evolutionary related proteins.

PMID- 4347745
TI  - Hyperbaric medicine in the US Air Force.

PMID- 4347747
TI  - Vascular catheter protection and storage devices.

PMID- 4347746
TI  - [Case of co-existing primary liver cancer and renal cancer clinically diagnosed
      prior to death].

PMID- 4347748
TI  - Implantation and use of a subcutaneous culture chamber in laboratory animals.

PMID- 4347749
TI  - A purified gel diet for guinea pigs.

PMID- 4347750
TI  - Intestinal microsporidiosis in Callicebus moloch.

PMID- 4347751
TI  - Intraspecies variation in serum cholesterol levels in imported Macaca nemestrina.

PMID- 4347752
TI  - The surgical preparation and maintenance of pigs in biovailability studies.

PMID- 4347753
TI  - Housing for aquatic animals.

PMID- 4347754
TI  - Cardiac puncture in laboratory animals.

PMID- 4347755
TI  - Bordetella bronchiseptica in laboratory cats from central California.

PMID- 4347756
TI  - Staphylococcal botryomycosis in a specific-pathogen-free mouse colony.

PMID- 4347757
TI  - Spontaneous occurrence and experimental transmission of the fungus, Fonsecaea
      pedrosoi, in the marine toad, Bufo marinus.

PMID- 4347758
TI  - Comparison of hematologic values from peripheral blood of the ear and venous
      blood of infant baboons (Papio cynocephalus).

PMID- 4347759
TI  - Postnatal development of the prairie vole, Microtus ochrogaster.

PMID- 4347760
TI  - Maintaining frugivorous phyllostomatid bats in the laboratory: Phyllostomus,
      Artibeus, and Sturnira.

PMID- 4347761
TI  - Influence of acclimation upon rectal temperatures of rabbits subjected to
      controlled environmental conditions.

PMID- 4347762
TI  - Experimental rubella virus infection of marmosets (Saguinus species).

PMID- 4347763
TI  - Niclosamide as a treatment for Hymenolepis nana and Hymenolepis diminuta in rats.

PMID- 4347764
TI  - Outdoor housing of nonhuman primates.

PMID- 4347765
TI  - Intraocular pressure in the juvenile rhesus monkey (Macaca mulatta) by
      applanation tonometry. Preliminary report.

PMID- 4347766
TI  - The use of fetal animals to investigate renal development.

PMID- 4347768
TI  - Chemodectomas of the nasopharynx. An unusual case associated with unilateral
      ocular proptosis.

PMID- 4347767
TI  - Experimental kidney transplantation.

PMID- 4347769
TI  - Malignant insulinoma with hepatic secondaries treated with hepatic artery
      ligation.

PMID- 4347770
TI  - The range of carcinogenic substances in human foods and the problems of testing
      for them.

PMID- 4347771
TI  - Respiratory infection which requires surgical management.

PMID- 4347772
TI  - Hepatic ultrastructure in endotoxemia, hemorrhage, and hypoxia: emphasis on
      mitochondrial changes.

PMID- 4347773
TI  - [Study of a transferable plasmid causing H 2 S production and tetracycline
      resistance in Escherichia coli].

PMID- 4347774
TI  - Plasmid-linked tetracycline and erythromycin resistance in group D
      "streptococcus".

PMID- 4347776
TI  - [Benign synovioma of the hand].

PMID- 4347775
TI  - R factors identified in Paris, some conferring gentamicin resistance, constitute
      a new compatibility group.

PMID- 4347777
TI  - The effect of electro-convulsive therapy on the urinary excretion of adenosine
      3':5'-cyclic monophosphate.

PMID- 4347778
TI  - The effect of glucagon on adenosine 3':5'-cyclic monophosphate concentrations in
      an organ culture of adult rat liver.

PMID- 4347779
TI  - Micro methods of osmometry based on the equilibrium swelling of gels.

PMID- 4347781
TI  - Mechanisms for the control of enzymic rates.

PMID- 4347780
TI  - Binding of rat liver and hepatoma polyribosomes to stripped rough endoplasmic
      reticulum in vitro. Biological or an artifact?
AB  - Exposed thiol groups do not appear to be related to the binding of (32)P-labelled
      polyribosomes to stripped rough endoplasmic reticulum in vitro. Treating stripped
      rough endoplasmic reticulum with GSSG did not diminish binding of polyribosomes,
      suggesting that binding in vitro has no correlation with the inhibition of
      protein synthesis in vitro reported by Kosower et al. (1971). Thiol reagents,
      which are known to dissociate ribosomes, did not significantly decrease binding
      of (32)P-labelled polyribosomes to stripped rough endoplasmic reticulum.
      Denaturing the protein of (32)P-labelled polyribosomes or stripped rough
      endoplasmic reticulum of liver or hepatoma with heat, trichloroacetic acid, or
      HClO(4) did not alter the binding in vitro. Therefore, the practice of measuring
      the binding of (32)P-labelled polyribosomes to stripped rough endoplasmic
      reticulum in vitro (Shires et al., 1971b) is an unsuitable indicator of
      biological significance in the intact cell.

PMID- 4347782
TI  - Structure and function of liver fructose 1,6-diphosphatase.

PMID- 4347784
TI  - Preliminary investigations on bovine hepatic fructose 1,6-diphosphatase.

PMID- 4347783
TI  - Localization of D-myoinositol 1:2-cyclic phosphate 2-phosphohydrolase in rat
      kidney.
AB  - 1. On subcellular fractionation of rat kidney homogenates by differential and
      density-gradient centrifugation, the bulk of the inositol 1:2-cyclic phosphate 2
      phosphohydrolase activity remains with the alkaline phosphatase activity,
      suggesting localization in the brush borders of the proximal tubules. 2.
      Histochemical studies with a medium containing inositol 1:2-cyclic phosphate and
      Escherichia coli phosphomonoesterase show Gomori staining around the brush
      borders of the proximal tubules in the outer cortex only. 3. Serial sections
      across the kidney from cortex perimeter to papilla suggest that the inositol 1:2
      cyclic phosphate 2-phosphohydrolase has a limited distribution along the proximal
      tubule of the nephron, probably being limited to the pars convoluta, whereas the
      alkaline phosphatase extends along the pars recta.

PMID- 4347785
TI  - Spin-spin interaction between molybdenum and one of the iron-sulphur systems of
      xanthine oxidase and its relevance to the enzymic mechanism.
AB  - 1. Electron-paramagnetic-resonance (e.p.r.) studies at 9 and 35GHz at helium
      temperatures have given new information relating to the structure and mechanism
      of action of xanthine oxidase. 2. As reported by others, the enzyme gives two
      types of e.p.r. signal attributed to iron-sulphur systems. The first has
      g(av.)=1.95. Parameters of the second are determined as g(1) 2.12, g(2) 2.007 and
      g(3) 1.91, with g(av.)=2.01. This species seems to have a slightly higher redox
      potential than the former one. 3. Temperature-dependent changes in the form of
      Mo(v) e.p.r. signals from the enzyme, observed under certain conditions, are
      shown to be due to weak spin-spin interaction between Mo(v) and g(av.)=1.95 Fe/S.
      The phenomenon has been studied most fully for the Slow Mo(v) signal. Here, the
      spectral change takes the form of an additional approximately isotropic 11G
      splitting, detected below about 45 degrees K only. Samples without Fe/S reduced
      showed no such changes of spectrum. 4. Similar spectral changes were observed in
      the Rapid Mo(v) signals, obtained in rapid-freezing experiments, but only in
      samples corresponding to relatively long reaction times with the substrate. It is
      suggested therefore that the phenomenon may provide a means of distinguishing
      enzyme centres with Mo only reduced from those in which both Mo and Fe/S are
      reduced. 5. Additional rapid-freezing data tending to support a two- rather than
      a one-electron transfer of reducing equivalents from substrates to xanthine
      oxidase are reported.

PMID- 4347786
TI  - Some properties of guinea-pig liver fructose 1,6-diphosphatase in relation to the
      control of gluconeogenesis.

PMID- 4347787
TI  - The development of some enzymes of gluconeogenesis in the liver and kidney of the
      foetal guinea pig.

PMID- 4347789
TI  - D- and L-lactate dehydrogenases of Pseudomonas aeruginosa.

PMID- 4347788
TI  - The effect of oxygen concentration on the growth and metabolism of Saccharomyces
      cerevisiae grown with excess of potassium or in potassium-deficient media.
AB  - 1. Saccharomyces cerevisiae cells grown in limiting K(+) concentration have their
      growth inhibited by O(2) concentrations above 40%. With these conditions the
      cells grow very large and are unable to maintain ionic gradients when washed with
      water. 2. Cells grown in excess of K(+) showed the same pattern of change in cell
      size with change in O(2) concentration, but the magnitude of the changes was much
      less. Cells grown in excess of K(+) were not leaky. 3. Cell death, growth and
      development of ;leakiness' were not correlated in the cells grown in limiting
      K(+) concentration. 4. The activities of both alcohol dehydrogenase and
      cytochrome oxidase were higher in K(+)-deficient cells than in the cells grown
      with excess of K(+). The differences were much larger when the measurements were
      made on a cellular basis than when made on a protein basis. 5. In 100% O(2) 3mm
      K(+) in the medium was sufficient to produce normal yeast cells.

PMID- 4347790
TI  - Metabolism of piperonylate by Pseudomonas fluorescens.

PMID- 4347791
TI  - The effect of local anaesthetics on lipolysis in fat-cells.

PMID- 4347792
TI  - Influence of a 17 beta-sulphate group on reduction of a steroid 3-oxo group by
      cortisone reductase.

PMID- 4347793
TI  - A major influence of a 1 alpha, 2 alpha-methylene group on reduction of a steroid
      3-oxo group by 2 nicotinamide-adenine dinucleotide-linked 3-hydroxy steroid
      oxidoreductases.

PMID- 4347794
TI  - Functional groups in the catalysis and regulation of Escherichia coli citrate
      synthase.

PMID- 4347795
TI  - The regulation of Acinetobacter sp. alpha-oxoglutarate dehydrogenase complex.

PMID- 4347796
TI  - Some properties of yeast isocitrate dehydrogenase.

PMID- 4347797
TI  - Activation and phosphorylation of the subunits of phosphorylase kinase.

PMID- 4347798
TI  - Temporal aspects of glucose metabolism in the rat at birth.

PMID- 4347799
TI  - Increased phospholipid depletion alters the apparent specificity of phospholipid
      dependence of glucose 6-phosphatase activity.

PMID- 4347800
TI  - Rabbit heart valve basement membrane: low platelet reactivity.

PMID- 4347801
TI  - [Effect of imidazole compounds on neuromuscular synapses with changes in medium
      pH].

PMID- 4347802
TI  - [Effect of bacterial collagenase on collagen synthesized in the presence of
      azetidine-2-carboxylic acid].

PMID- 4347803
TI  - [Bronchial carcinoma in young adulthood. Case report].

PMID- 4347804
TI  - Mitochondria and respiratory enzymes of L cells treated with actinomycin D.

PMID- 4347805
TI  - Surface alterations in transformed epithelial and fibroblastic cells in culture:
      a disturbance of membrane degradation versus biosynthesis?

PMID- 4347806
TI  - Synthesis of serum proteins by a clonal strain of rat hepatoma cells.

PMID- 4347807
TI  - The synthesis of surface coat materials in normal and transformed cells.

PMID- 4347808
TI  - Animalizing ability of Evans blue in embryos of Arbacia punctulata. Effect on
      multiple molecular forms of NAD-L-malate dehydrogenase.

PMID- 4347809
TI  - Ultrastructural study of the action of aminopiperazines on transformed cell lines
      and on nervous system tissue culture.

PMID- 4347810
TI  - Cleavage inhibition in marine eggs by puromycin and 6-dimethylaminopurine.

PMID- 4347811
TI  - Studies on cyclic AMP levels and phosphodiesterase activity in developing sea
      urchin eggs. Effects of puromycin, 6-dimethylamino purine and aminophylline.

PMID- 4347812
TI  - A growth factor for animal cells derived from peptone. II. Effect of the growth
      factor on cellular metabolism.

PMID- 4347813
TI  - The pathway from the mediodorsal nucleus of thalamus to the hypothalamus in the
      cat.

PMID- 4347814
TI  - Primary afferent hyperpolarization without postsynaptic potentiation.

PMID- 4347815
TI  - Caudate intracellular response to thalamic and cortical inputs.

PMID- 4347816
TI  - Intracellular responses of caudate neurons to temporally and spatially combined
      stimuli.

PMID- 4347817
TI  - Convergence in the lumbar spinal cord of pathways activated by splanchnic nerve
      and hind limb cutaneous nerve stimulation.

PMID- 4347818
TI  - Membrane junctions in growth and differentiation.

PMID- 4347819
TI  - Emergency medical services: new program for old problem.

PMID- 4347820
TI  - Cytochemistry of experimental protein malnutrition in primates: effect on the
      spinal cord of the squirrel monkey, Saimiri sciureus.

PMID- 4347823
TI  - Renin-angiotensin system in chronically hypophysectomized rats.

PMID- 4347822
TI  - Effects of insulin on the lipolytic system of rat fat cells.

PMID- 4347821
TI  - Anti-insulin eeffect of cortisol in deep hypoglycemia of the rat: sex
      differences.

PMID- 4347824
TI  - Metabolic effects of a medium-chain triglyceride emulsion injected intravenously
      in man.

PMID- 4347825
TI  - An investigation of clinical applications of mesomorphic cholesteric liquid
      crystals in podiatric medicine. A preliminary study.

PMID- 4347826
TI  - Angiotensin II like activity in the plasma of normal subjects and patients with
      renal hypertension.

PMID- 4347828
TI  - Renin-angiotensin system and hypertension.

PMID- 4347827
TI  - Serum, spinal fluid and neural total lipids, phospholipids and cholesterol in
      diabetes mellitus and non-diabetic neuropathy.

PMID- 4347829
TI  - Motility of spermatozoa and control of bacteria in bovine semen diluents
      contining penicillin and neomycin or epicillin.

PMID- 4347830
TI  - Histopathological study of a quartz-filled composite dental restorative material.

PMID- 4347831
TI  - Subcellular distribution of NADH cytochrome c reductase in rat gingiva.

PMID- 4347832
TI  - [Plastic surgery of the tracheobronchial tree].

PMID- 4347833
TI  - Molecular complexity of Paramecium symbiont lambda deoxyribonucleic acid:
      evidence for the presence of a multicopy genome.

PMID- 4347834
TI  - The typical dream: case studies.

PMID- 4347835
TI  - [Physiologic mechanism of inflammation, especially in redintegration].

PMID- 4347836
TI  - [Change in the intensity of NAD-H 2  fluorescence in Candida guilliermondii
      yeasts during transition from anaerobic to aerobic states].

PMID- 4347838
TI  - [Tumours of the temporal bone].

PMID- 4347837
TI  - [Use of chemotherapy in combination with surgery and irradiation in cases of
      nephroblastoma (Wilm's tumor)].

PMID- 4347839
TI  - [Determination of free radicals in the placenta by the method of electron
      paramagnetic resonance and their relation to enzymes of the oxidation-reduction
      group].

PMID- 4347840
TI  - Respiratory smooth muscle relaxing effect of commercial steroid preparations.

PMID- 4347841
TI  - Hypertension with aldosterone excess.

PMID- 4347842
TI  - A vista of research on the mammalian gonadotropins. Carl G. Hartman Lecture.

PMID- 4347843
TI  - The cyclic AMP system of human brain.

PMID- 4347844
TI  - Evidence of electrotonic transmission in the vestibular nuclei of the rat.

PMID- 4347845
TI  - Cortical interneurons during sleep and waking in freely moving primates.

PMID- 4347846
TI  - Effects of serotonin metabolites on sleep-waking activity in cats.

PMID- 4347847
TI  - Some evidence for the existence of dopaminergic neurons in the rat cortex.

PMID- 4347848
TI  - Benzodiazepines and posttetanic potentiation in sympathetic ganglia of the
      bullfrog.

PMID- 4347849
TI  - The modification of the pupillary light reflex by chlorpromazine, diazepam, and
      pentobarbital.

PMID- 4347850
TI  - Responses of single units in the medulla to genital stimulation in estrous and
      anestrous cats.

PMID- 4347851
TI  - [Synovialoma of the knee joint].

PMID- 4347852
TI  - The effect of thoracic duct lymph drainage in myasthenia gravis.

PMID- 4347853
TI  - [Determination of free silicon dioxide in small quantities of dust by the
      fluoride method].

PMID- 4347854
TI  - Influence of calcium on angiotensin II--antibody reaction.

PMID- 4347855
TI  - The interaction of chaotropic anions with acid ferricytochrome c.

PMID- 4347856
TI  - Fatty acid inhibition of sulfation factor-stimulated  35 SO 4  incorporation into
      embryonic chicken cartilage.

PMID- 4347858
TI  - Relation of glucagon-specific binding sites to glucagon-dependent stimulation of
      adenylyl cyclase activity in plasma membranes of rat liver.

PMID- 4347857
TI  - Regulation of fatty acid synthesis in isolated hepatocytes prepared from the
      livers of neonatal chicks.

PMID- 4347859
TI  - Yeast inorganic pyrophosphatase. VI. Studies on specificity and mechanism.

PMID- 4347860
TI  - Characteristics of the human lymphocyte insulin receptor.

PMID- 4347861
TI  - Control of glycogen synthase phosphatase from rat heart. The role of substrate.

PMID- 4347863
TI  - The mystery virus. The elusive E-B virus: guilty or not guilty?

PMID- 4347862
TI  - A method for the estimation of some synthetic glucocorticosteroids in rat muscle.

PMID- 4347864
TI  - The use of rivanol for the removal of nonspecific inhibitors of rubella virus
      haemagglutinin.

PMID- 4347865
TI  - Corticoreticulospinal control of the tonic vibration reflex in the cat.

PMID- 4347866
TI  - Control of the tonic vibration reflex by the brain stem reticular formation in
      the cat.

PMID- 4347867
TI  - Measurement of plasma renin activity by angiotensin I radioimmunoassay: (I) an
      assessment of some methodological aspects.

PMID- 4347868
TI  - The role of the contractile vacuole in the osmoregulation of Tetrahymena
      pyriformis.

PMID- 4347869
TI  - m-Chlorobenzhydroxyamic acid--an inhibitor of cyanide-insensitive respiration in
      Trypanosoma brucei.

PMID- 4347870
TI  - Inhibition of protein synthesis: a mechanism of amebicide action of emetine and
      other structurally related compounds.

PMID- 4347871
TI  - Differentiation during encystment and excystment in Oxytricha fallax.

PMID- 4347872
TI  - [Antiviral activity of thiourea derivatives].

PMID- 4347873
TI  - The chick as a laboratory model for the study of estrogen-induced hyperlipidemia.

PMID- 4347874
TI  - Genetic obesity in rats. II. The effect of food restriction on the metabolism of
      adipose tissue.

PMID- 4347876
TI  - A sheep in a wolf's coat.

PMID- 4347875
TI  - Progress in endocrinology and metabolism. Vitamin D: current concepts.

PMID- 4347877
TI  - [Isolated trigeminal neuropathy].

PMID- 4347878
TI  - [Biological maturity in the light of electroencephalographic studies].

PMID- 4347879
TI  - [Diagnostic value of enzyme examination in cerebrospinal fluid].

PMID- 4347880
TI  - Current status of virological research in human leukemias and sarcomas.

PMID- 4347881
TI  - Recruitment, loudness and the stapedial reflex threshold under hypnosis.

PMID- 4347882
TI  - Examination of the liver using radio-active rose bengal. Clinical results of the
      Department of Radio-Isotopes, H.F. Verwoerd Hospital, Pretoria, 1963-1972.

PMID- 4347883
TI  - The oxygen uptake of alveolar and peritoneal macrophages during phagocytosis of
      toxic and non-toxic dust particles.

PMID- 4347884
TI  - Cytomegalic inclusion disease. Pediatric grand rounds.

PMID- 4347885
TI  - [Isolation of proteins typical of normal and malignant growth from rat serum].

PMID- 4347886
TI  - [Desmoplasia of the myothelium in so-called mixed tumours].

PMID- 4347888
TI  - Malignant tumors of infancy and childhood.

PMID- 4347887
TI  - The neuron doctrine: a revision of functional concepts.

PMID- 4347889
TI  - [Histogenesis of Abrikossov's tumor].

PMID- 4347890
TI  - [Results of organ cultivation of human stomach and rectal neoplasms].

PMID- 4347891
TI  - [Nature and mechanisms of changes in cells during neoplastic evolution].

PMID- 4347892
TI  - [Lung chemodectomas].

PMID- 4347893
TI  - Enzymatic cyclization of neryl pyrophosphate to  -terpineol by cell-free extracts
      from peppermint.

PMID- 4347894
TI  - Effect of metabolic inhibitors on the agglutination of tumor cells by
      concanavalin A and Ricinus communis agglutinin.

PMID- 4347895
TI  - Antiestrogens: studies using an in vitro estrogen-responsive uterine system.

PMID- 4347896
TI  - Cyclic AMP-induced differentiated neuroblastoma cells: changes in total nucleic
      acid and protein contents.

PMID- 4347897
TI  - , -Methylene-adenosine-5'-triphosphate--effects of a competitive inhibitor of
      adenylate cyclase on cyclic AMP accumulation and lipolysis in isolated fat cells.

PMID- 4347898
TI  - The interaction of  -cyclodextrin with nucleic acid monomer units.

PMID- 4347899
TI  - The characterization of rat kidney plasma membranes prepared by zonal
      centrifugation.
AB  - 1. Plasma membranes were isolated from a 10000g-min pellet prepared from a renal
      cortical homogenate in 20mm-NaHCO(3) by isopycnic centrifugation in a linear
      sucrose gradient in an ;A'-type zonal rotor. 2. The preparation was characterized
      by electron microscopy, and alkaline phosphatase, 5'-nucleotidase, l-leucine beta
      naphthylamidase and l-leucine p-nitroanilidase activities were found to be
      selectively associated with the renal plasma membrane. 3. The preparation had a
      high degree of purity, as indicated by the presence of low activities of marker
      enzymes associated with subcellular organelles. A preliminary chemical analysis
      indicated that the chemical composition resembled that of plasma membranes of
      other tissues. 4. Plasma membranes were also prepared from tubular fragments and
      their enzyme contents were found to be similar to those of plasma membranes
      prepared from cortical homogenates. 5. l-Leucine beta-naphthylamidase, l-leucine
      p-nitroanilidase and 5'-nucleotidase were not enriched to the same extent as
      alkaline phosphatase in the preparation of plasma membranes from tubular
      fragments. A possible explanation for this finding is discussed.

PMID- 4347900
TI  - The role of adenosine 3':5'-cyclic monophosphate in the regulation of insulin
      release. Properties of islet-cell adenosine 3':5'-cyclic monophosphate
      phosphodiesterase.
AB  - 1. An assay has been developed with sufficient sensitivity for determination of
      the adenosine 3':5'-cyclic monophosphate diesterase activity in islets of
      Langerhans, and has been used to investigate the response of the enzyme to
      various agents which are known to affect insulin release. 2. The subcellular
      distribution of the enzyme in islets of Langerhans prepared from guinea-pig
      pancreas was investigated and over 70% of the activity present in the original
      homogenate was recovered in the supernatant fraction. 3. Gel filtration of the
      activity present in the supernatant fraction on Sephadex G-200 gave a single peak
      of activity with an apparent molecular weight of 200000. The phosphodiesterase
      activity in the peak fraction showed two apparent K(m) values for adenosine 3':5'
      cyclic monophosphate (cyclic AMP) of 3mum and 30mum, suggesting the presence of
      two activities. The pH optimum of the activity with the low K(m) value was 8.7.
      4. Theophylline, caffeine, 3-isobutyl-1-methylxanthine (SC-2964), glibenclamide,
      tolbutamide, xylitol and leucine were inhibitors of the activity with the low
      K(m) value; imidazole and arginine stimulated the activity, and glucose and
      diazoxide were without significant effect. 5. It is suggested that the agents
      theophylline, caffeine, SC-2964, glibenclamide, tolbutamide, leucine and
      imidazole may alter the intracellular concentration of cyclic AMP in islets of
      Langerhans by affecting the cyclic AMP phosphodiesterase activity in islet cells
      and in this way may affect insulin release.

PMID- 4347901
TI  - The effect of two inhalation anesthetics on the order of spin-labeled
      phospholipid vesicles.

PMID- 4347902
TI  - Pressure reversal of inhalation anesthetic-induced disorder in spin-labeled
      phospholipid vesicles.

PMID- 4347903
TI  - Membrane fractions from rat hepatoma. II. Immunochemical characterization of
      detergent-soluble membrane esterases, glycosidases and leucyl- -naphthylamidase.

PMID- 4347904
TI  - Membrane fractions from rat hepatoma. 3. Immunochemical characterization of
      detergent-soluble membrane phosphatases, electron transport chains and catalase.

PMID- 4347905
TI  - Levels of membrane marker enzyme activity in normal and RNA and DNA virus
      transformed fibroblasts.

PMID- 4347906
TI  - Respiratory viral infections in hospital patients with chronic bronchitis.
      Observations during periods of exacerbation and quiescence.

PMID- 4347907
TI  - Nomenclature explosion.

PMID- 4347908
TI  - Pulmonary blastoma; longterm survival of juvenile patient.

PMID- 4347909
TI  - Three simultaneous multiple primary carcinomas in one patient.

PMID- 4347910
TI  - An appraisal of routine methods for the determination of the anodal isoenzymes of
      lactate dehydrogenase.

PMID- 4347912
TI  - [Herpes infections in childhood].

PMID- 4347911
TI  - The role of cyclic AMP and calcium in cell activation.

PMID- 4347914
TI  - Effect of 5-bromodeoxyuridine on the structure of differentiating choroid plexus
      cells in vitro.

PMID- 4347913
TI  - The relationship of the level of cyclic amp to differentiation in primary
      cultures of chick muscle cells.

PMID- 4347915
TI  - Stable alterations in HeLa cell mitochondria following ethidium bromide
      treatment.

PMID- 4347916
TI  - A quantitation of movement of marker particles in the plasma membrane of 3T3
      mouse fibroblasts. Experimental methods.

PMID- 4347917
TI  - A quantitative difference in the movement of marker particles in the plasma
      membrane of 3T3 mouse fibroblasts and their polyoma transformants.

PMID- 4347918
TI  - [The role of cyclic AMP in the secretion and mechanism of action of hormones].

PMID- 4347919
TI  - Cystosarcoma phyllodes.

PMID- 4347920
TI  - Problems peculiar to brain malignancies.

PMID- 4347921
TI  - Secondary carcinomatous deposits in the skeletal muscles in association with non
      metastatic carcinomatous neuromyopathy.

PMID- 4347922
TI  - Absolute configuration of a metabolite in the m-fission pathway of
      protocatechuate.
AB  - An aldolase, which is induced in Pseudomonas testosteroni during growth with p
      hydroxybenzoate, preferentially attacks the R form of 4-hydroxy-4-methyl-2
      oxoglutarate, a metabolite of protocatechuate catabolism.

PMID- 4347923
TI  - Membrane lipids of Mycoplasma hominis.
AB  - Essentially all of the lipids of Mycoplasma hominis (200 mug/mg of cell protein)
      were found to be located in the cell membrane. Over one-half were neutral lipids
      incorporated from the growth medium and consisting of 43% free cholesterol, 19%
      esterified cholesterol, 23% triglycerides, 10% free fatty acids, and small
      amounts of di- and monoglycerides. The polar lipids accounting for about 40% of
      the total were synthesized by the organisms. Phosphatidylglycerol was the
      predominant lipid of this fraction. The minor components, tentatively identified
      as lysophosphatidylglycerol and phosphatidic acid, seem to represent breakdown
      products of phosphatidylglycerol. No glycolipids were detected. Being unable to
      synthesize long-chain fatty acids, M. hominis utilized the fatty acids of the
      growth medium for polar lipid synthesis, preferentially the saturated ones, so
      that the polar lipids had highly saturated hydrocarbon chains. It is proposed
      that the large take up of unsaturated neutral lipids and cholesterol from the
      medium offsets the marked condensing effect of the saturated polar lipids,
      although electron paramagnetic resonance spectrometry of spin-labeled fatty acids
      incorporated into the M. hominis membrane indicated that the lipid region is
      still more rigid than that of the Acholeplasma laidlawii membrane.

PMID- 4347924
TI  - Control of pantothenate accumulation in Agrobacterium tumefaciens.
AB  - Two pantothenate-requiring mutants of Agrobacterium tumefaciens have been
      isolated. One of them (strain WMP-1) is unusual in that growth levels equivalent
      to the parent strain are achieved only when the medium is additionally
      supplemented with aspartate or another compound related to the tricarboxylic acid
      cycle. Extracts of cells grown on limiting aspartate were found to contain four
      times more (14)C-pantothenate than those grown at optimal aspartate
      concentrations. This difference was found in both the perchloric acid-soluble and
      -insoluble fractions, presumably the coenzyme A pool and acyl carrier protein,
      respectively. These findings are discussed in terms of membrane integrity and the
      control of fatty acid biosynthesis.

PMID- 4347926
TI  - Chromatographically fractionated complementary strands of Bacillus subtilis
      deoxyribonucleic acid: transformation of hybrids.
AB  - The annealing properties as measured by the restoration of transforming activity
      and hypochromicity of methylated albumin-kieselguhr (MAK)-fractionated
      complementary strands of Bacillus subtilis deoxyribonucleic acid (DNA) are
      presented. Temperature-absorbance measurements performed on annealed mixtures of
      various L and H strand fractions indicated the existence of a complementarity
      gradient between the two MAK peaks. The markers purA16, leu-8, metB(5), thr-5,
      and the linked marker hisB(2)-try-2 exhibited different bimodal distributions on
      MAK columns. The transforming efficiency of heteroduplex mixtures, prepared by
      cross-annealing resolved complementary strands of wild-type and recipient DNA,
      was compared. The transforming efficiency of the wild-type L and H strands was
      equal in one preparation and unequal in a second preparation. It was found that
      in the second strand preparation the heteroduplex DNA containing the H strand
      from wild type was more efficient for all of the markers tested. The variations
      in transforming efficiencies of the complementary strands in heteroduplex
      molecules reported here and by others are due in part to strands of unequal
      length and probably to the self-annealing property of the H strands. At present,
      no conclusion could be made regarding the existence of strand selection bias
      during integration of donor DNA in competent B. subtilis cells.

PMID- 4347925
TI  - Chromatographically fractionated complementary strands of Bacillus subtilis
      deoxyribonucleic acid: biological properties.
AB  - Biological, physical, and chromatographic properties of methylated
      albuminkieselguhr (MAK)-fractionated complementary strands, designated as light
      (L) and heavy (H), of Bacillus subtilis deoxyribonucleic acid (DNA) are
      presented. The pattern of transforming activity along the MAK elution profile of
      alkilidenatured DNA shows that the residually active molecules selectively
      fractionated ahead of the L strand fraction, whereas the most active self
      annealed molecules fractionated preferentially at the trailing end of the H
      strand fraction. The restoration rate of transforming activity in the late
      eluting H molecules was rapid and independent of concentration during the
      annealing reaction. The data suggest that the self-annealing activity in the H
      strand is due in part to the formation of intrastrand secondary structures.
      Hydroxyapatite chromatography of self-annealed L and H strands yielded a major
      fraction (I) of highly purified strand preparations devoid of transforming
      activity and hypochromicity, and a minor "nativelike" fraction (II).
      Sedimentation velocity measurements show that, in addition to the mutual
      complementary nature of the L and H fractions, they differ in molecular size and
      possibly configuration.

PMID- 4347927
TI  - Role of adenosine 3',5'-cyclic monophosphate and its specific binding protein in
      the regulation of D-serine deaminase synthesis.
AB  - Adenosine 3',5'-cyclic monophosphate (cyAMP) and the cyAMP-binding protein are
      necessary for efficient induction of d-serine deaminase (Dsdase) synthesis in
      dsdC(+)dsdO(+) and dsdC dsdO(+) strains of Escherichia coli K-12, and for
      constitutive synthesis in dsdC dsdO(+) strains. Neither is required in dsdO
      strains, confirming previous indications that in dsdO mutants Dsdase synthesis is
      not subject to catabolite repression control. Since efficient Dsdase synthesis in
      dsdC(+) and dsdC strains that are dsdO(+) requires the cyAMP-binding protein,
      which acts at the level of transcription in other systems, it is concluded that
      catabolite repression acts at the level of transcription of the Dsdase structural
      gene. Since catabolite repression is reversed by the inducer, d-serine in dsdC
      dsdO(+) strains, it is concluded that induction also acts at the level of
      transcription in this system. The dsdC strains were found to be much more
      sensitive to induction by d-serine than are dsdC(+) strains under conditions of
      catabolite repression, whether the repression was caused by glucose or by loss of
      ability to form cyAMP or cyAMP-binding protein. This suggests that a d-serine
      dsdC complex may be able to replace partially the cyAMP:cyAMP-binding protein
      action in initiation of Dsdase messenger ribonucleic acid synthesis-a positive
      control effect.

PMID- 4347928
TI  - Isolation and characterization of mutations affecting the transport of hexose
      phosphates in Escherichia coli.
AB  - Mutants of Escherichia coli defective in the hexose phosphate transport system
      were isolated. Negative selection by penicillin treatment or positive selection
      with phosphonomycin was employed. These mutants grew normally on all carbon
      sources other than hexose phosphates. The map location of the mutations in 18
      independently isolated mutant strains was investigated by transduction crosses.
      All of the mutations were found to lie in the same region of the chromosome, in
      the region represented by min 72 on the Taylor map. The order of the genes in
      this region was found to be mtl-cysE-pyrE-uhp-bgl-ilv. Revertants of some of the
      mutants exhibited altered regulatory control of this transport system.

PMID- 4347929
TI  - Metabolism of D-fructose by Arthrobacter pyridinolis.
AB  - Previous studies showed that Arthrobacter pyridinolis can transport and utilize d
      glucose only after prior growth on certain Krebs cycle intermediates. In
      contrast, we found that d-fructose was taken up and metabolized by A. pyridinolis
      without special prior conditions of growth. d-Fructose was first converted to d
      fructose-1-phosphate by a phosphoenolpyruvate (PEP):D-fructose
      phosphotransferase. This activity required both supernatant and pellet fractions
      from d-fructose-grown cells centrifuged at 150,000 x g. The d-fructose-1
      phosphate formed was converted to d-fructose-1, 6-diphosphate. Mutants deficient
      in PEP:d-fructose phosphotransferase and d-fructose-1-phosphate kinase, or d
      fructose-1, 6-diphosphatase (FDPase) were unable to grow on d-fructose but
      retained the normal ability to use d-glucose. Mutants forming reduced amounts of
      FDPase were completely unable to grow on d-fructose but were still capable of
      limited growth on Krebs cycle intermediates. A requirement for higher levels of
      FDPase for growth on d-fructose than for growth on Krebs cycle intermediates was
      also indicated by the higher specific activities of FDPase in d-fructose-grown
      cells than in cells grown on l-malate or amino acids.

PMID- 4347930
TI  - Time of enterotoxin formation and release during sporulation of Clostridium
      perfringens type A.
AB  - Clostridium perfringens enterotoxin was detected intracellularly about 3 hr after
      the inoculation of vegetative cells into sporulation medium. The subsequent
      increase in intracellular enterotoxin concentration roughly paralleled but
      followed by 2.5 to 5 hr the increase in number of heat-resistant spores. The
      increase in biologically active toxin coincided with the increase in enterotoxin
      antigen. Enterotoxin was released from the sporangium with its lysis,
      concomitantly with the mature spore release.

PMID- 4347931
TI  - A comparison of two methods of prognostic typing in breast cancer.
AB  - The value of two different systems for the prognostic assessment of breast cancer
      has been tested by comparing a group of 74 long-term survivors with a group of 54
      short-term survivors. The system devised by Bloom and Richardson (1957) gave a
      good general correlation with prognosis. Appearances described by Harveit (1971)
      showed some correlation with prognosis but were rarely seen in our cases. The
      degree of lympho-plasmacytic infiltrate did not show any correlation with
      prognosis.

PMID- 4347932
TI  - [Participation of aortic arch and carotid sinus baroreceptors in acute pressor
      reactions in experimental renal hypertension].

PMID- 4347933
TI  - Effects of reserpine on sleep and brain biogenic amine levels in the cat.

PMID- 4347934
TI  - Juvenile nasopharyngeal haemangiofibroma.

PMID- 4347935
TI  - [Clostridium infections--gas gangrene].

PMID- 4347937
TI  - [Alkylmercapto-bisalkylsulfonyl- and trisalkylmercapto-propanes].

PMID- 4347936
TI  - [Oxidation of  -aminoketones].

PMID- 4347938
TI  - Herpes simplex and zoster.

PMID- 4347939
TI  - Actinomycin D for Wilms's tumour.

PMID- 4347940
TI  - Oral contraceptives.

PMID- 4347941
TI  - Physiological and genetic studies of polyoma virus.

PMID- 4347942
TI  - [Protein kinase in the nervous system].

PMID- 4347944
TI  - Pseudo-cowpox (paravaccinia) in dairy cows.

PMID- 4347945
TI  - [Usefulness of Nadi's reaction in the diagnosis of the nervous system and
      muscles].

PMID- 4347946
TI  - [Case of sporadic form of primary amyloidosis].

PMID- 4347948
TI  - [Berylliosis].

PMID- 4347949
TI  - Bronchography in diseases of the adult chest.

PMID- 4347947
TI  - [Two fast hemoglobins in Ivory-Coast: Hb K Woolwich and a new hemoglobin Hb J
      Abidjan (alpha-51 Gly-Asp)].

PMID- 4347950
TI  - Radiographic aspects of pulmonary infection in patients with altered immunity.

PMID- 4347951
TI  - [Status and tendencies in lymphographic contrast media research].

PMID- 4347952
TI  - [Comparative studies on new administration routes for Lipiodol UF and 20 per cent
      Lipiodol emulsion in animals].

PMID- 4347953
TI  - [Experimental lymphography with contrast media systems of different particle
      size].

PMID- 4347954
TI  - [Experiments on thoracic duct lymphography by resorption of iodized oils from the
      digestive tract].

PMID- 4347955
TI  - [Current status of the treatment of infantile acute leukemias].

PMID- 4347956
TI  - Maternal-fetal endocrine interrelations: influence of maternal
      adrenocorticosteroids on fetal ACTH secretion.

PMID- 4347957
TI  - Angiotensin II, diuretics, and thoracic duct lymph flow in the dog.

PMID- 4347958
TI  - Cheap labor from poor nations.

PMID- 4347959
TI  - Stimulation of aldosterone secretion by hemorrhage in dogs after nephrectomy and
      decapitation.

PMID- 4347960
TI  - Roentgen evaluation of Wilms' tumor.

PMID- 4347961
TI  - Synthesis of cyclic AMP and phosphodiesterase in various species of cellular
      slime molds and its bearing on chemotaxis and differentiation.

PMID- 4347962
TI  - Metabolism of ethanol and fructose in the isolated perfused pig liver.

PMID- 4347963
TI  - A sequence of 50 nucleotides from coliphage R17 RNA.

PMID- 4347964
TI  - Chemodectoma with metastasis to bone in a dog.

PMID- 4347965
TI  - Metabolism of phenol and cresols by mutants of Pseudomonas putida.
AB  - Mutant strains of Pseudomonas putida strain U have been obtained which are
      deficient in enzymes of the degradative pathways of phenol and cresols. Mutant
      strains deficient in catechol 2, 3-oxygenase accumulated the appropriate catechol
      derivative from cresols. A mutant strain which would not grow on either phenol or
      a cresol was shown to be deficient in both 2-hydroxymuconic semialdehyde
      hydrolase and a nicotinamide adenine dinucleotide, oxidized form, (NAD(+))
      dependent aldehyde dehydrogenase. When this strain was grown in the presence of
      phenol or a cresol, the appropriate product of meta fission of these compounds
      accumulated in the growth medium. A partial revertant of this mutant strain,
      which was able to grow on ortho- and meta-cresol but not para-cresol, was shown
      to have regained only the hydrolase activity. This strain was used to show that
      the products of meta ring fission of the cresols and phenol are metabolized as
      follows: (i) ortho- and meta-cresol exclusively by a hydrolase; (ii) para-cresol
      exclusively by a NAD(+)-dependent aldehyde dehydrogenase; (iii) phenol by both a
      NAD(+)-dependent dehydrogenase and a hydrolase in the approximate ratio of 5 to
      1. This conclusion is supported by the substrate specificity and enzymatic
      activity of the hydrolase and NAD(+)-dependent aldehyde dehydrogenase enzymes of
      the wild-type strain. The results are discussed in terms of the physiological
      significance of the pathway. Properties of some of the mutant strains isolated
      are discussed.

PMID- 4347966
TI  - Salmonella typhimurium mutants lacking ribonuclease I: effect on the polarity of
      histidine mutants.
AB  - Mutants of Salmonella typhimurium containing 1 to 2% of wild-type ribonuclease I
      activity were isolated. The rns mutation had no effect on the polarity of
      mutations in the S. typhimurium histidine operon. Even in the presence of an rns
      mutation, it was not possible to obtain strong suppressors of the polarity of two
      polar mutations in the his operon.

PMID- 4347967
TI  - Purification and identification of the fruiting-inducing substances in Coprinus
      macrorhizus.
AB  - Substances which are effective in inducing fruiting bodies in monokaryotic
      mycelia of the fis(+) strain of Coprinus macrorhizus were purified and
      characterized. The active components of fruiting-inducing substances were
      identified as adenosine-3'-monophosphate, adenosine 3',5'-cyclic monophosphate
      (cyclic AMP), and a protein which is bound with the cyclic AMP. Cyclic AMP was
      synthesized from adenine within mycelia of the mutant strains which form
      monokaryotic fruiting bodies without the addition of fruiting-inducing
      substances, but not in those of the strains which do not form monokaryotic
      fruiting bodies. The proteins which bind with cyclic AMP were detected in crude
      extracts of mycelia of those strains which form monokaryotic fruiting bodies and
      of the dikaryon, but not in those of the strains which do not form monokaryotic
      fruiting bodies.

PMID- 4347968
TI  - Metabolism of adenosine 3',5'-cyclic monophosphate and induction of fruiting
      bodies in Coprinus macrorhizus.
AB  - The adenyl cyclase and phosphodiesterase metabolizing adenosine 3',5'-cyclic
      monophosphate (cyclic AMP) were detected in mycelia of strains of Coprinus
      macrorhizus which form fruiting bodies, but not in those of strains which do not
      form fruiting bodies. The adenyl cyclase synthesized cyclic AMP from adenosine
      triphosphate. The phosphodiesterase degr[UNK]ded cyclic AMP to adenosine-5'
      monophosphate and was inhibited by adenosine-3'-monophosphate, theophylline, and
      caffeine. The strains which form fruiting bodies incorporated and metabolized
      cyclic AMP, but strains which do not form fruiting bodies did not. The possible
      participation of cyclic AMP in the induction of fruiting bodies is discussed.

PMID- 4347970
TI  - Proton magnetic resonance spectroscopy of Klebsiella capsular polysaccharides.
AB  - The presence of acetate and pyruvate groups in Klebsiella capsular
      polysaccharides may be demonstrated and estimated quantitatively by running the
      proton magnetic resonance spectrum of the polysaccharide (as sodium salt) in
      deuterium oxide at 95 C. Such spectra also permit an assessment to be made of the
      number of alpha- and beta-linkages in the repeat unit of the polysaccharide
      structure.

PMID- 4347969
TI  - Sequential metabolic events during encystment of Azobacter vinelandii.
AB  - Cells of Azotobacter vinelandii are specifically induced to encyst by beta
      hydroxybutyrate (BHB). The process of differentiation, which occurs over a period
      of 36 h, was characterized by an ordered sequence of biochemical events. Upon
      initiation of encystment, nitrogen fixation and glucose-6-phosphate dehydrogenase
      activities decreased immediately to very low levels. This was followed by an
      increase in the specific activities of BHB dehydrogenase, isocitrate
      dehydrogenase, isocitrate lyase, and malate synthase first at 3 h and then again
      at 21 h. The peak activity of fructose 1,6-diphosphate aldolase occurred at 6 h,
      and the enzyme activity then decreased gradually. Fructose 1,6-diphosphatase had
      peak activities at 9 and 27 h. Deoxyribonucleic acid synthesis ceased just prior
      to the final cell division at 4 to 6 h, but ribonucleic acid synthesis continued
      until the 12th h. From labeling studies and the appearance of new enzyme
      activities, it appeared that protein synthesis continued throughout encystment.

PMID- 4347971
TI  - Regulation of manganese accumulation and exchange in Bacillus subtilis W23.
AB  - An overnight culture of Bacillus subtilis W23 in low-manganese tryptone broth is
      unable to sporulate and becomes hyperactive with regard to the manganese active
      transport system during stationary phase. When manganese is added to cells in
      spent or fresh medium, the cells immediately accumulate a high proportion of the
      manganese available in the medium. When the hyperactive cells are diluted into
      broth containing 10 muM Mn(2+), high intracellular manganese levels are reached,
      and inhibition of ribonucleic acid and protein synthesis occurs. This inhibition
      is relieved when the intracellular manganese concentration declines to the
      nontoxic levels characteristic of cells growing in 10 muM Mn(2+). The release of
      the accumulated manganese is achieved by a reduction in the uptake rate for
      manganese while the efflux rate remains essentially constant. Inhibitors of
      ribonucleic acid and protein synthesis prevent the reduction of the high rate of
      manganese uptake and, therefore, high net concentrations of manganese are
      maintained in the presence of these inhibitors. The hyperactive manganese uptake
      system is temperature dependent and inhibited by cyanide and m-chlorophenyl
      carbonylcyanide hydrazone.

PMID- 4347972
TI  - Requirement of adenosine-3',5'-cyclic monophosphate for L-arabinose isomerase
      synthesis in Escherichia coli.
AB  - Adenosine-3', 5'-cyclic monophosphate (cyclic AMP) is essential for the synthesis
      of l-arabinose isomerase in Escherichia coli. Cyclic AMP appears to be required
      for the transcription of deoxyribonucleic acid into messenger ribonucleic acid
      (RNA), since the enzyme synthesis is not observed in induced cells to which
      cyclic AMP is added after messenger RNA synthesis is arrested by rifampin or
      after inducer removal.

PMID- 4347973
TI  - Fine structure of Cryptococcus neoformans grown in vitro as observed by freeze
      etching.
AB  - Cryptococcus neoformans grown on culture media was observed by the freeze-etching
      technique. In the capsule, short fibrils were seen when freezeetched. This
      organism was unique in the appearance of the cell wall, which showed two strata.
      The outer one was dense with particles of about 20 nm in diameter, whereas the
      inner one was sparse in particles. The appearance of the cell membrane of this
      organism differed distinctly depending on the culture media. When grown on
      glycerol medium, the cell membrane possessed, as do other yeasts, clear but
      somewhat longer and curved invaginations. The membrane of cells grown on
      nonglycerol medium exhibited, however, only a few invaginations of irregular
      shape. Instead, characteristically of this organism, the cell membrane showed
      round depressions of 40 to 200 nm in diameter which were the surface view of the
      paramural bodies. In cross-fractured cells, both types of paramural bodies were
      found. Some of them contained a single vesicle of about 50 nm in diameter. These
      seem to play a role in secreting the cytoplasmic vesicles. Data suggesting the
      existence of multivesicular bodies in the cytoplasm and multivesicular lomasomes
      were also obtained. Some of the baglike paramural bodies showed multilayered
      membrane. These are thought to be plasmalemmasomes. This organism was similar to
      other yeasts reported in other respects.

PMID- 4347974
TI  - Cyclic-nucleotide phosphodiesterase: an early defect in inherited retinal
      degeneration of C3H mice.
AB  - Cyclic nucleotides have been implicated in the differentiation and function of
      the vertebrate retina. In the normal retina of DBA mice, the specific activity of
      cyclic-nucleotide phosphodiesterase (PDE), with cyclic-AMP as the substrate (cAMP
      PDE), increases eightfold between the 6th and 20th postnatal day. Kinetic
      analysis of retinae from newborn mice reveals a PDE with a single Michaelis
      constant (K(m)) value for cyclic-AMP (low K(m)-PDE). After the 6th postnatal day,
      a second PDE with a high K(m) for cyclic-AMP (high K(m)-PDE) can be demonstrated.
      The appearance and increasing activity of the high K(m)-PDE coincides with the
      differentiation and growth of photoreceptor outer segments. Additionally, the
      high K(m)-PDE is shown by microchemical techniques to be concentrated in the
      photoreceptor cell layer and the low K(m)-PDE within the inner layers of the
      normal retina. In C3H mice afflicted with an inherited degeneration of the
      photoreceptor layer, the postnatal increase in the specific activity of cAMP-PDE
      is substantially lower than in the normal retina. The postnatal increase in the
      specific activity of cAMP-PDE in two regions of the brain of C3H mice is the same
      as in the normal strain. A deficiency in high K(m)-PDE activity in the C3H retina
      is evident on the 7th postnatal day, when the activity of low K(m)-PDE,
      photoreceptor morphology, and rhodopsin content of these retina are essentially
      normal. In the adult C3H retina, the PDE activity with cyclic-GMP and cyclic-UMP
      as substrates is significantly below that of the normal retina. These data
      indicate that an alteration in cyclic-AMP metabolism occurs before photoreceptor
      cell degeneration in the retinae of C3H mice.

PMID- 4347975
TI  - Growth of normal and transformed rat embryo fibroblasts: effects of glycolipids
      from Salmonella minnesota R mutants.
AB  - Addition of glycolipids obtained from Salmonella minnesota R mutants to normal,
      spontaneously transformed, and SV40-transformed rat embryo fibroblasts in culture
      results in an inhibition of growth of transformed cells but not of normal cells.
      In the presence of the glycolipid with the smallest carbohydrate chain length,
      spontaneously transformed cells stop growing when they reach confluency.
      Inhibition of growth of transformed cells is inversely related to the chain
      length of the core sugars. Glycolipid mR595 is shown to bind with the cell
      membrane of transformed cells and elicits an augmentation in the intracellular
      level of cyclic AMP. Normal cells bind relatively less glycolipid mR595 and show
      a lower percent of increase in cyclic AMP due to glycolipid mR595 than do
      transformed cells.

PMID- 4347976
TI  - Cell membrane resorption in the rat exocrine pancreas cell after in vivo
      stimulation of the secretion, as studied by in vitro incubation with
      extracellular space markers.
AB  - Pancreatic secretion in the rat was stimulated in vivo by pilocarpine injection
      causing 90% of the storage granules to be discharged within 2 h. Incubation in
      vitro with [(14)C]sorbitol indicated that maximal ingestion of this extracellular
      space marker occurred 3 h after secretogogue injection. Morphological cell
      membrane measurements on cells with stimulated secretion revealed a simultaneous
      decrease in amount of membrane bordering the microvilli at the cell apex,
      lamellar processes, and infoldings present at the latero-basal face of these
      cells. In 3-h stimulated cells, having the average zymogen granule content
      characteristic for that phase of secretion, ferritin treatment in vitro showed
      that the infoldings and related fragmentation vesicles had ingested ferritin and
      could consequently be considered as being transport vehicles for redundant cell
      membrane. During stimulated secretion numerous vesicles and vacuoles appeared in
      the apical cytoplasm. Part of these structures were postulated to be related to
      the Golgi complex and were discussed in relation to secretory protein transport.
      Another part of these structures was assumed to have an endocytotic nature,
      although they never contained ferritin.

PMID- 4347977
TI  - Secretion of collagen by corneal epithelium. I. Morphology of the collagenous
      products produced by isolated epithelia grown on frozen-killed lens.
AB  - Corneal epithelium from 5-7-day old chick embryos was isolated with EDTA and
      grown in culture on frozen-killed lens as a substratum. Autoradiographs showed
      that in the presence of [(3)H]proline, the corneal epithelium synthesized and
      secreted onto the lens substratum, radioactive materials resistant to extraction
      by sodium hydroxide. The radioactive label was associated with newly formed
      striated collagen fibrils, large "sheets" of collagen, and basal lamina. The
      repeat period and interband pattern of the abundant new collagen sheets and
      fibrils was typical of "native" or so-called "mesenchymal" collagen. Collagen
      like materials were observed in secretory (Golgi) vacuoles within the corneal
      cells and collagen fibrils within the intercellular canals (lateral interfaces)
      of the epithelium, as well as at the base of the cells. Both the granular
      endoplasmic reticulum and Golgi complexes were highly developed in the corneal
      epithelium. In the discussion, the role of cytoplasmic organelles in collagen
      secretion, the origin and structure of the basal lamina, and variations in
      collagen polymerization patterns in vitro are reviewed and evaluated. The
      morphogenetic significance of the synthesis and secretion of collagen by
      embryonic epithelium is appraised and the production of true native-striated
      collagen by epithelium is stressed.

PMID- 4347978
TI  - Membrane fusion during mast cell secretion.

PMID- 4347979
TI  - Dimethyl sulfoxide-induced reversion of several features of polyoma transformed
      baby hamster kidney cells (BHK-21). Alterations in growth and morphology.
AB  - Cells of a polyoma virus transformed clonal line (Cl-I) of baby hamster kidney
      fibroblasts (BHK-21) were grown in medium containing 2 percent dimethylsulfoxide
      (DMSO). Unlike the untransformed BHK-21 cells, Cl-I cells adapted to replication
      in the presence of DMSO, and they exhibited a rapidly reversible phenotypic
      reversion of a number of properties characteristic of the transformed state.
      Restoration of density dependent growth inhibition with accumulation of cells in
      the G(1) phase of the cell cycle occurred and was associated with restoration of
      contact dependent behavior and with reversion of histological and ultrastructural
      features towards those which characterize untransformed cells. Concomitantly, Cl
      I cells grown in 2 percent DMSO lost the ability to form colonies in semisolid
      medium. The data presented suggest that DMSO alters the expression of cellular
      functions which were altered as a result of viral transformation and which may be
      involved in cell tumorigenicity.

PMID- 4347981
TI  - Periodic variation in A-V conduction time: the 'supernormal' phase of A-V
      conduction. A study in differential dual A-V pathway conductivity and
      refractoriness.

PMID- 4347980
TI  - Axonal agranular reticulum and synaptic vesicles in cultured embryonic chick
      sympathetic neurons.
AB  - Cultured chick embryonic sympathetic neurons contain an extensive axonal network
      of sacs and tubules of agranular reticulum. The reticulum is also seen branching
      into networks in axon terminals and varicosities. The axonal reticulum and
      perikaryal endoplasmic reticulum resemble one another in their content of
      cytochemically demonstrable enzyme activities (G6Pase and IDPase) and in their
      characteristic membrane thicknesses (narrower than plasma membrane or some Golgi
      membranes). From the reticulum, both along the axon and at terminals, there
      appear to form dense-cored vesicles ranging in size from 400 to 1,000 A in
      diameter. These vesicles behave pharmacologically and cytochemically like the
      classes of large and small catecholamine storage vesicles found in several
      adrenergic systems; for example, they can accumulate exogenous 5-hydroxydopamine.
      In addition, dense-cored vesicles at the larger (1,000 A) end of the size
      spectrum appear to arise within perikaryal membrane systems associated with the
      Golgi apparatus; this is true also of very large (800-3,500 A) dense-cored
      vesicles found in some perikarya.

PMID- 4347982
TI  - Lung uptake of  99m Tc-sulfur colloid.

PMID- 4347984
TI  - Apomorphine antagonism of the elevation of homovanillic acid induced by
      antipsychotic drugs.

PMID- 4347983
TI  - Interpretation of the  67 Ga photoscan.

PMID- 4347985
TI  - Effects of angiotensin II on cyclic 3'5'AMP in rat uterus.

PMID- 4347986
TI  - Effect of cholecystokinin on the level of cyclic AMP and on mechanical activity
      in the isolated sphincter of Oddi.

PMID- 4347987
TI  - Spontaneous transmitter release and ACh sensitivity during glutaraldehyde
      fixation of rat diaphragm.

PMID- 4347989
TI  - A functional connection between postganglionic neurons in a bullfrog sympathetic
      ganglion.

PMID- 4347990
TI  - Evidence for sodium dependent outward transport of the  3 H-norepinephrine
      mobilized by calcium at the adrenergic synapse. Inhibition of transport by
      desipramine.

PMID- 4347988
TI  - Adenyl cyclase-phosphodiesterase system in arterial smooth muscle.

PMID- 4347991
TI  - The mechanism of the drinking response to some hypotensive drugs: activation of
      the renin-angiotensin system by direct or reflex-mediated stimulation of  
      receptors.

PMID- 4347993
TI  - Two morphologically distinct blood-brain barriers preventing entry of cytochrome
      c into cerebrospinal fluid.
AB  - After intravenous injection, cytochrome c does not enter the cerebrospinal fluid.
      In most areas of the brain, the marker is prevented from leaving cerebral vessels
      by the capillary endothelium. In the choroid plexus, the marker passes freely out
      of capillaries into the extracellular space. However, it does not traverse tight
      junctions between epithelial cells and is rapidly incorporated into mnembrane
      bound vesicles within the cell cytoplasm. Thereafter, cytochrome c is apparently
      removed by lysosomal degradation. These data suggest that there are at least two
      morphologically distinct blood-brain barriers to cytochrome c and that
      pinocytosis may be a mechanism for intracellular degradation rather than
      transcellular transport.

PMID- 4347994
TI  - Immunologic manipulation of metastases due to herpesvirus transformed cells.
AB  - Herpes simplex virus type 1 (HSV-1), type 2 (HSV-2), and simian virus 40 (SV40)
      fail to induce immunity in weanling Syrian hamsters to transplant of hamster
      cells transformed by HSV-2. However, the development of metastatic tumors is
      markedly enhanced by prior immunization with HSV-1. Immunization with SV40,
      ultraviolet-irradiated tumor cells, or ultraviolet-irradiated normal hamster
      embryo cells inhibits the development of metastases. The HSV-hamster system
      appears a good one for the study of development, prevention, and control of
      metastases by mammalian cells transformed by a common human virus.

PMID- 4347992
TI  - Effects of colchicine and cytochalasin B on the release of  3 H-norepinephrine
      from guinea-pig atria evoked by high potassium, nicotine and tyramine.

PMID- 4347995
TI  - [Genetic analysis of animal viruses. I. Methods].

PMID- 4347996
TI  - [Electron microscopy study on the histogenesis of granular neuroma].

PMID- 4347998
TI  - Neonatal hypoglycaemia due to an islet-cell adenoma.

PMID- 4347997
TI  - Development of tone-burst responses along the auditory pathway in the cat.

PMID- 4347999
TI  - [Lightcoagulation therapy in pit of the optic nerve with detachment of the macula
      luteae].

PMID- 4348000
TI  - Immunosuppression during pregnancy: transmission of azathioprine and its
      metabolites from the mother to the fetus.

PMID- 4348001
TI  - Passage of polymyxins from serum into milk in ewes.

PMID- 4348002
TI  - Failure of either corticosteroids or ACTH to increase the leukocyte concentration
      in milk.

PMID- 4348003
TI  - Clinical course and histopathologic features of pseudorabies virus-induced
      keratoconjunctivitis in pigs.

PMID- 4348004
TI  - Oncogenic activity of feline fibrosarcoma virus in newborn pigs.

PMID- 4348005
TI  - Estimation of plasma renin activity by radioimmunoassay of angiotensin I.

PMID- 4348007
TI  - Generation of phenoxy radicals by methemoglobin-hydrogen peroxide studies by
      electron paramagnetic resonance.

PMID- 4348006
TI  - Cyclic AMP phosphodiesterase activity at the external surface of intact skeletal
      muscles and stimulation of the enzyme by insulin.

PMID- 4348008
TI  - The effects of local anesthetics on lipid multilayers. A spin probe study.

PMID- 4348009
TI  - Collagen proline hydroxylase activity in the uterus of the rat during rapid
      collagen synthesis in vivo.

PMID- 4348011
TI  - A membrane-bound alkaline inorganic pyrophosphatase in isolated spinach
      chloroplasts.

PMID- 4348010
TI  - The hydrolysis of triphosphoinositide by a phosphodiesterase in rat kidney
      cortex.

PMID- 4348012
TI  - Deuterium isotope effects in the oxidation of alcohols in vitro and in vivo.

PMID- 4348015
TI  - Interaction of pyruvate with pyruvate carboxylase and pyruvate kinase as studied
      by paramagnetic effects on  13 C relaxation rates.

PMID- 4348014
TI  - Diphosphopyridine nucleotide-linked D-lactate dehydrogenases from the horseshoe
      crab, Limulus polyphemus, and the seaworm, Nereis virens. II. Catalytic
      properties.

PMID- 4348013
TI  - Diphosphopyridine nucleotide-linked D-lactate dehydrogenases from the horseshoe
      crab, Limulus polyphemus and the seaworm, Nereis virens. I. Physical and chemical
      properties.

PMID- 4348017
TI  - A stimulation by phosphate of malate transport and oxidation in rat adrenal
      mitochondria.

PMID- 4348016
TI  - Protein synthesis in chicken muscular dystrophy.

PMID- 4348018
TI  - Measurement of the water exchange rate of bound water in the manganese(II)
      adenosine triphosphate complex by oxygen-17 nuclear magnetic resonance.

PMID- 4348019
TI  - The effect of maternal hypoxia on fetal pituitary hormone release in the sheep.

PMID- 4348020
TI  - Biochemical properties of human fetal mitochondria.

PMID- 4348021
TI  - Usefulness of solid medium in Myjak's application (3) for current laboratory
      diagnostics of amoebiasis.

PMID- 4348022
TI  - Effects of morphine on the Golgi apparatus and mitochondria of mammalian
      neurones.

PMID- 4348023
TI  - Chromosome and chromatid exchanges in Chinese hamster cells.

PMID- 4348024
TI  - [Third oral polio immunization--what is the good of it?].

PMID- 4348026
TI  - Bronchogenic carcinoma: the true story.

PMID- 4348025
TI  - [Value of stimulation and detection electrodiagnostics in occupational
      traumatology and pathology. II].

PMID- 4348027
TI  - Nobel Prize winner talks about noradrenaline, nerves and aging.

PMID- 4348029
TI  - [Findings on post-operative carotid arteriograms].

PMID- 4348030
TI  - [Histogenesis of granulated cell tumors].

PMID- 4348031
TI  - [Desiccating therapy of macerated tinea pedum].

PMID- 4348028
TI  - [Calcified liver metastases from islet cell carcinoma].

PMID- 4348033
TI  - Reticulum cell sarcoma and malignant histiocytoma of the soft tissues.

PMID- 4348034
TI  - Sequential studies on spontaneous mammary and hepatocarcinogenesis in reciprocal
      crosses of ICRC and C3H (Jax) strains.

PMID- 4348035
TI  - Mapping of sites on the surface membrane of mammalian cells. II. Relationship of
      sites for concanavalin A and an ornithine, leucine copolymer.

PMID- 4348032
TI  - Calcium, cyclic adenosine 3',5'-monophosphate, and the control of cell
      proliferation: a review.

PMID- 4348036
TI  - Neuropathy of metachromatic leucodystrophy.
AB  - We describe two patients with metachromatic leucodystrophy who presented with
      peripheral neuropathy and had no evidence of central nervous system involvement
      at the time of presentation. Such an occurrence is not well recognized and the
      diagnosis is usually missed until the other features of the disease manifest
      themselves. Early recognition of this disease may become of practical importance
      from the point of view of therapy, judging from recent developments, and is also
      important from the point of view of genetic counselling. We suggest that cases of
      peripheral neuropathy in infancy and childhood, should be subjected to peripheral
      nerve biopsy when the aetiology is not obvious.

PMID- 4348037
TI  - Differential sensitivity of motor and sensory fibres in human ulnar nerve.
AB  - The human ulnar nerve has been stimulated with square-wave pulses of various
      fixed durations. Measurements were made of the growth of hand myograms compared
      with elbow neurograms and of hand myograms compared with finger neurograms, for
      fixed durations of pulses and increasing strength. The effect of blocking sensory
      action potentials with stimuli of various durations has been investigated, as
      well as the blocking of action potentials in motor nerve fibres by voluntary
      activity. It is concluded that pulses of long duration (1 msec or more)
      selectively stimulate sensory fibres at threshold, whereas short duration pulses
      (less than 200 MUsec) selectively stimulate motor fibres.

PMID- 4348038
TI  - Effect of procaine infiltration into biceps brachii muscle in man on supraspinal
      control of reflex transmission.
AB  - Sensitivity of the tonic stretch reflex (TSR) of biceps brachii in normal man was
      measured at different levels of voluntary contraction before and after gamma
      efferent nerve fibres were selectively blocked by infiltration of dilute
      procaine. The procaine infiltration reduced TSR sensitivity to one half of its
      control value. It had no effect, however, on the slope of the relation between
      TSR gain and level of voluntary contraction. It was concluded that the increase
      in TSR sensitivity associated with voluntary contraction was not mediated by the
      gamma efferent fibres and control of reflex transmission is therefore not the
      main function of the fusimotor system.

PMID- 4348040
TI  - [Mode of stimulation reception in the vestibular apparatus--action current of the
      peripheral branch of the vestibular nerve].

PMID- 4348039
TI  - [Nasopharyngeal cancer].

PMID- 4348041
TI  - Metabolic neuropathy.

PMID- 4348043
TI  - Cytotoxic effect of viruses on Harding-Passey melanoma in tissue culture.

PMID- 4348042
TI  - Oxaluria.

PMID- 4348044
TI  - Induction of virus synthesis in polyoma-transformed BHK-21 cells.
AB  - BHK-21 cells were transformed with polyoma virus mutants Ts-a and Ts-25 by using
      a temperature shift from 31 to 39 C at 5 days after infection so that rescuable
      transformants could be isolated. Clones which yielded virus after fusion with
      mouse cells were scored and maintained at 39 C in the presence of antipolyoma
      virus antiserum. Generally, no infectious viral deoxyribonucleic acid (DNA) could
      be found in Hirt supernatant fractions of these lines when maintained at 39 C,
      but DNA-DNA reannealing measurements detected two to six viral genomes per
      diploid cell genome in the nuclear DNA. Fusion with permissive cells was not
      necessary to induce the synthesis of infectious virus; cell lines shifted to 31 C
      produce the equivalent of 100 viral genomes per cell after 5 days. In some cell
      lines up to 1% of the cells formed infectious centers upon a shift to 31 C, and
      100% of the subclones of a line were inducible. Growth at 31 C selected for a
      noninducible population which was still transformed.

PMID- 4348045
TI  - The influence of rare earths on hepatic gluconeogenesis.

PMID- 4348046
TI  - Actions of various cyclic nucleotides, nucleosides and purine bases on the
      synthesis of corticosterone in vitro.

PMID- 4348047
TI  - Effect of dibutyryl cyclic-AMP on levels of dopamine- -hydroxylase in isolated
      superior cervical ganglia.

PMID- 4348048
TI  - Erythropoiesis in the yolk sac of the early chick embryo: an electron microscope
      and microspectrophotometric study.

PMID- 4348049
TI  - Light-induced changes in the ultrastructure of a plasmodial myxomycete.

PMID- 4348050
TI  - Freeze-fractured lamellar body membranes of the rat lung great alveolar cell.

PMID- 4348051
TI  - Ultrastructural changes in the nuclear envelope of larval fat body cells of
      Simulium vittatum (Diptera) induced by microsporidian infection of Thelohania
      bracteata.

PMID- 4348053
TI  - Cytodifferentiation of maturing pine tracheids: the final stage.

PMID- 4348052
TI  - Histology and ultrastructure of the tube foot epithelium in the phanerozonian
      starfish, Astropecten.

PMID- 4348054
TI  - The ultrastructure and function of pericardial cells and other nephrocytes in an
      insect: Calliphora erythrocephala.

PMID- 4348055
TI  - [A clinico-statistical analysis of operable and inoperable stomach cancer
      patients].

PMID- 4348056
TI  - Fibrous xanthomas and xanthosarcomas of the meninges and the brain.

PMID- 4348058
TI  - Oncogenic viruses.

PMID- 4348057
TI  - Hemorrhage from cecal ulcers of cytomegalovirus infection: report of a case.

PMID- 4348059
TI  - Ultrastructure of lipid bodies and lysosomes in the skin in Fabry's disease
      (angiokeratoma corporis diffusum).

PMID- 4348060
TI  - Susceptibility of chick brain L-glutamic acid decarboxylase and other
      neurotransmitter enzymes to hyperbaric oxygen in vitro.

PMID- 4348061
TI  - Testosterone-stimulation of adenyl cyclase and cyclic 3',5'-adnosine
      monophosphate- 3 H formation in rat seminal vesicles.

PMID- 4348063
TI  - Structure and reactions of oxygenase active centers: cytochrome P-450 and iron
      sulfur proteins.

PMID- 4348062
TI  - Effects of clofibrate, in vitro, on mitochondrial respiration and oxidative
      phosphorylation.

PMID- 4348064
TI  - Haem protein P-450 from the adrenal cortex: interaction with steroids and the
      hydroxylation reaction.

PMID- 4348065
TI  - Cholesterol hydroxylation in the adrenal cortex and liver.

PMID- 4348066
TI  - A study of transfer RNA methylation.

PMID- 4348067
TI  - Hydroxylamine-dependent reactions catalyzed by a lysyl-tRNA synthetase of
      Escherichia coli B.

PMID- 4348068
TI  - Kinetics of synthesis of cytochromes   and   3  during respiratory adaptation of
      yeast.

PMID- 4348069
TI  - Purification of superoxide dismutase from fungi and characterization of the
      reaction of the enzyme with catechols by electron spin resonance spectroscopy.

PMID- 4348070
TI  - Cyclic AMP-induced differentiated mouse neuroblastoma cells lose tumourgenic
      characteristics.

PMID- 4348071
TI  - [Neurologic symptomatology of fluorosis. Accidental findings or expression of
      organic manifestation?].

PMID- 4348072
TI  - [50th contribution of the Central Expert Committee for Drug Trade, Section Human
      Medicine].

PMID- 4348073
TI  - Alkaline and acid phosphatase in the intestines of rats infected with a virulent
      strain of Entamoeba histolytica and treated with emetine and Flagyl.

PMID- 4348074
TI  - Microspectrophotometric analysis of malarial pigment.

PMID- 4348075
TI  - Schistosoma mansoni: histochemical analysis of the postacetabular gland secretion
      of cercariae.

PMID- 4348076
TI  - Transient increase in capillary permeability induced by Clostridium perfringens
      type A enterotoxin.
AB  - A transient increase in capillary permeability was induced in the skin of guinea
      pigs by Clostridium perfringens type A enterotoxin. Maximum intensity and maximum
      diameter of the area of increased capillary permeability were obtained with
      injection of enterotoxin 10 to 20 min before dye injection.

PMID- 4348077
TI  - Foot-and-mouth disease virus: selection by homogenized calf kidney adsorption and
      cell culture passage.
AB  - Foot-and-mouth disease virus was passaged 20 times by alternately adsorbing the
      virus with homogenized calf kidney and propagating the adsorption-resistant
      fraction of virus in cell cultures. Passage of the virus was accompanied by a
      marked decrease in pathogenicity for 35-day-old mice and a reduction in its
      ability to adsorb to homogenized kidney from such mice. Adsorption by homogenized
      calf kidney and infant mouse kidney also decreased with passage, but
      pathogenicity for cattle and infant mice remained high. The passaged virus did
      not seem to change antigenically. When the 20th-passage virus was serially
      passaged 10 times in cell cultures, no reversion in pathogenicity for 35-day-old
      mice was observed.

PMID- 4348078
TI  - Isolation and characterization of Mycoplasma conjunctivae sp. n. from sheep and
      goats with keratoconjunctivitis.
AB  - Fourteen conjunctival strains of mycoplasma were isolated from infected sheep and
      goats in two separate naturally occurring outbreaks of keratoconjunctivitis (pink
      eye). The biological and serological properties and cell protein patterns of
      these strains are presented in this report. These strains were related to each
      other and were unrelated to 40 recognized Mycoplasma and Acholeplasma species and
      serotypes. We are proposing that this group of mycoplasmas be named M.
      conjunctivae. The role of M. conjunctivae in the etiology of keratoconjunctivitis
      in sheep and goats remains to be determined.

PMID- 4348079
TI  - Saccadic inhibition induced by brain-stem stimulation in the alert monkey.

PMID- 4348080
TI  - Conformational changes in membranous preparations of cytochrome oxidase.

PMID- 4348081
TI  - Proteins of cytochrome oxidase in fractions prepared with deoxycholate from
      bovine heart submitochondrial particles.

PMID- 4348082
TI  - Variability of the K+-Na+ discrimination of beauvericin in mitochondrial
      membranes.

PMID- 4348083
TI  - [Effect of a methaqualone diphenhydramine combination on the sleep of healthy
      people].

PMID- 4348084
TI  - [Collagen metabolism in combined therapy of rheumatoid arthritis].

PMID- 4348086
TI  - In vitro transformation assay of major fractions of cigarette smoke condensate
      (CSC) in mammalian cell lines.

PMID- 4348085
TI  - Cation activated hydrolysis of ATP by the soluble fraction of Bacillus brevis.

PMID- 4348087
TI  - Changes in rat liver plasma membrane phospholipids during aging.

PMID- 4348088
TI  - The effect of chloroquine on herpesvirus infection in vitro and in vivo.

PMID- 4348089
TI  - The nature of collagen in the carrageenin granuloma.

PMID- 4348090
TI  - Effect of cyclophosphamide on the genetic resistance of C 3 H mice to mouse
      hepatitis virus.

PMID- 4348091
TI  - The effects of prostaglandin E 1  on erythropoietin production.

PMID- 4348092
TI  - Effect of angiotensin II on uptake and release of dl- 3 H-metaraminol.

PMID- 4348093
TI  - Regulation of the in vitro synthesis of angiotensin I.

PMID- 4348094
TI  - Reaction of endogenous renin with exogenous renin substrate within the isolate
      perfused rat kidney.

PMID- 4348095
TI  - Possible mechanisms of impaired interferon production in stressed mice.

PMID- 4348096
TI  - An in vivo corticotropin-releasing factor (CRF) assay based on plasma levels of
      radioimmunoassayable ACTH.

PMID- 4348097
TI  - Testosterone-induced depression of adrenergic activity in the perfused canin
      hindlimb.

PMID- 4348098
TI  - Extracellular localization of lysozyme in rachitic rat cartilage.

PMID- 4348099
TI  - Pyruvate dehydrogenase, the citrate condensing enzyme and the utilization of  14
      C-labeled lactate, pyruvate and alanine by slices of lactating mammary gland and
      adenocarcinoma of mouse mammary gland.

PMID- 4348100
TI  - Infection-mediated resistance to cell fusion by inactive Sendai virus.

PMID- 4348101
TI  - Sensitivity of human conjunctival tissue cultures to adenovirus 8, herpes simplex
      and vaccinia viruses. Induction of resistance by an interferon inducer.

PMID- 4348102
TI  - [Results of a radiologic study of 234 cases of breast cancer in women].

PMID- 4348103
TI  - [Clinical symptoms of cytomegaly in infants].

PMID- 4348104
TI  - [Determination of intrauterine age of the newborn infant born to a diabetic
      mother].

PMID- 4348105
TI  - [Activity of glycolytic enzymes and enzymes of the pentose phosphate cycle in
      erythrocytes of close relatives of children with hereditary spherocytosis].

PMID- 4348106
TI  - [Subserous stomach carcinoma].

PMID- 4348107
TI  - Ultrastructural modifications of frog urinary bladder epithelium under the
      influence of hypertonic media.

PMID- 4348108
TI  - [Fluorescence and electron microscopic studies of the pineal body in various
      species of birds].

PMID- 4348109
TI  - Angiography in the diagnosis and management of extrapancreatic islet-cell tumors.

PMID- 4348110
TI  - Histologic patterns of secondary syphilis.

PMID- 4348111
TI  - Recurrent skin cancer.

PMID- 4348113
TI  - Lateral geniculate spikes and eye movements in sleeping and awake cats following
      uni- and bilateral labyrinthectomy and cerebellar lesion.

PMID- 4348112
TI  - Epstein-Barr virus antibody levels in systemic lupus erythematosus.

PMID- 4348114
TI  - Studies on kinin-like substances in brain.

PMID- 4348115
TI  - Inhibitory effects of chlorpromazine and diethylaminoethyl diphenylvalerate (SKF
      525-A) on alanine incorporation into protein and  -aminoisobutyric acid uptake in
      rat hepatoma cells in culture.

PMID- 4348116
TI  - Effects of sodium salicylate and acetylsalicylic acid on the lipolytic system of
      fat cells.

PMID- 4348117
TI  - Antiparasitic nitroimidazoles. IV. Serum protein binding and mode of action of 2
      (4'-carboxystyryl)-5-nitro-1-vinylimidazole.

PMID- 4348118
TI  - Effect of rifampicin on mitochondrial protein synthesis in rat liver.

PMID- 4348119
TI  - [Synthesis of bis-homoanalogues of nucleosides].

PMID- 4348120
TI  - Effect of   9 - and   8 -tetrahydrocannabinol on the peripheral autonomic nervous
      system in vitro.

PMID- 4348121
TI  - The inhibition of sympathetic preganglionic neurons by somatic afferents.

PMID- 4348123
TI  - Hyperlipoproteinemia. Prevalence in a free-living population in Albany, New York.

PMID- 4348122
TI  - Vitamin A status and hepatic drug metabolism in the rat.

PMID- 4348124
TI  - Properties of the elongation factors from Escherichia coli. Exchange of
      elongation factor G during elongation of polypeptide chain.

PMID- 4348125
TI  - Purification of a phosphodiesterase from Bothrops atrox venom by affinity
      chromatography.

PMID- 4348126
TI  - Cytochrome c: a thermodynamic study of the relationships among oxidation state,
      ion-binding and structural parameters. 1. The effects of temperature, pH and
      electrostatic media on the standard redox potential of cytochrome c.

PMID- 4348127
TI  - Cytochrome c: a thermodynamic study of relationships among oxidation state, ion
      binding and structural parameters. 2. Ion-binding linked to oxidation state.

PMID- 4348128
TI  - Metabolic regulation of steroidogenesis in adrenocortical carcinoma cells of rat.
      Effect of adrenocorticotropin and adenosine cyclic 3':5'-monophosphate on
      corticosteroidogenesis.

PMID- 4348129
TI  - [Causes of intrauterine fetal death].

PMID- 4348130
TI  - Pleuro-pulmonary complications of amoebiasis.

PMID- 4348131
TI  - Hepato-pulmonary amoebiasis.

PMID- 4348132
TI  - The effect of topical corticosteroids on the susceptibility of immune animals to
      reinoculation with Herpes simplex.

PMID- 4348133
TI  - A modified method for the isolation of melanosomes from B16 melanoma.

PMID- 4348134
TI  - 'Collagenase-like peptidase in human, rat and bull spermatozoa.

PMID- 4348135
TI  - A general-purpose electronic model for arbitrary configurations of neurons.

PMID- 4348136
TI  - Relationship between ligand binding and conformational change of macromolecules
      in the two-state allosteric model.

PMID- 4348137
TI  - Theoretical implications of the size principle of motoneurone recruitment.

PMID- 4348138
TI  - Association of two contiguous urological tumors with adult Wilms tumor.

PMID- 4348139
TI  - Intraductal carcinoma of the prostate gland.

PMID- 4348140
TI  - Wilms tumor: a clinical pathological correlation.

PMID- 4348142
TI  - [Central nervous neurologic focal lesions in hypoglycemia. Changing neurologic
      focal symptoms due to glycopenia in islet-cell adenoma].

PMID- 4348141
TI  - Subcellular muscle studies in the prune belly syndrome.

PMID- 4348143
TI  - [Use of digital computers for optimization of the parameters of collimators for
      medical radioisotope scanning].

PMID- 4348144
TI  - The neuroleptics. 2. Neurophysiology and neuropharmacology.

PMID- 4348145
TI  - Histological and molecular biochemistry.

PMID- 4348146
TI  - SV40 virus-specific RNA synthesis in transformed human cells.

PMID- 4348147
TI  - Establishment of human malignant melanoma clonal cell lines that secrete ectopic
      adrenocorticotropin.

PMID- 4348148
TI  - Physiotherapy in the treatment of leprosy.

PMID- 4348149
TI  - Neuropathy in chronic renal disease.

PMID- 4348150
TI  - Catecholamine-containing neurones and electrical self-stimulation. 1. A review of
      some data.

PMID- 4348151
TI  - [Should ACTH be given after finished corticosteroid therapy?].

PMID- 4348152
TI  - Membrane resistance changes underlying the bipolar cell response in the carp
      retina.

PMID- 4348153
TI  - Bipolar-amacrine transmission in the carp retina.

PMID- 4348154
TI  - Viral hepatitis. Report of a WHO scientific group.

PMID- 4348156
TI  - [Demonstration of complement fixing antibodies in equine rhinovirus equine 1
      infection].

PMID- 4348155
TI  - [Echinococcal cysts in the peripheral nerves].

PMID- 4348157
TI  - Neutralization tests for foot-and-mouth disease, equine rhino-, porcine entero-,
      Aujeszky- and rhinopneumonitis viruses. Comparison of results obtained by a
      simple microculture plaque reduction test and various traditional tests.

PMID- 4348159
TI  - Coexistent congenital cytomegalovirus and toxoplasmosis in a stillborn.

PMID- 4348158
TI  - Comparison of isometric exercise and angiotensin infusion as stress test for
      evaluation of left ventricular function.

PMID- 4348160
TI  - Pain: a current view of neural mechanisms.

PMID- 4348161
TI  - [Isolation of organic bases as thiocyanate derivatives].

PMID- 4348162
TI  - On the kinetics of poliovirus-specific protein and RNA synthesis in poliovirus
      infected cells.

PMID- 4348163
TI  - Attempts to produce tumors in mice with CELO virus.

PMID- 4348164
TI  - Electron microscopic study of Sindbis virus morphogenesis.

PMID- 4348165
TI  - Isolation and characterization of reoviruses isolated from sheep.

PMID- 4348166
TI  - [Serological follow-up test on para-influenza-3-virus, Chlamydia, Coxiella
      burneti and IBR-virus antibodies, in a calf fattening farm].

PMID- 4348167
TI  - Mossbauer effect in rubredoxin. Determination of the hyperfine field of the iron
      in a simple iron-sulphur protein.
AB  - 1. Rubredoxin isolated from the green photosynthetic bacterium Chloropseudomonas
      ethylica was similar in composition to those from anaerobic fermentative
      bacteria. Amino acid analysis indicated a minimum molecular weight of 6352 with
      one iron atom per molecule. 2. The circular-dichroism and electron-paramagnetic
      resonance spectra of Ch. ethylica rubredoxin showed many similarities to those of
      Clostridium pasteurianum, but suggested that there may be subtle differences in
      the protein conformation about the iron atom. 3. Mossbauer-effect measurements on
      rubredoxin from Cl. pasteurianum and Ch. ethylica showed that in the oxidized
      state the iron (high-spin Fe(3+)) has a hyperfine field of 370+/-3kG, whereas in
      the reduced state (high-spin Fe(2+)) the hyperfine field tensor is anisotropic
      with a component perpendicular to the symmetry axis of the ion of about -200kG.
      For the reduced protein the sign of the electric-field gradient is negative, i.e.
      the ground state of the Fe(2+) is a [unk] orbital. There is a large non-cubic
      ligand-field splitting (Delta/k=900 degrees K), and a small spin-orbit splitting
      (D~+4.4cm(-1)) of the Fe(2+) levels. 4. The contributions of core polarization to
      the hyperfine field in the Fe(3+) and Fe(2+) ions are estimated to be -370 and 
      300kG respectively. 5. The significance of these results in interpretation of the
      Mossbauer spectra of other iron-sulphur proteins is discussed.

PMID- 4348168
TI  - Purine ribonucleotide biosynthesis, interconversion and catabolism in mouse brain
      in vitro.
AB  - The relative rates of the synthetic, interconversion and catabolic reactions of
      purine metabolism in chopped mouse cerebrum were studied. The rates of
      incorporation of [(14)C]adenine and [(14)C]hypoxanthine into purine
      ribonucleotides were much less than the potential activities of adenine
      phosphoribosyltransferase and hypoxanthine phosphoribosyltransferase, and the
      rates of incorporation were stimulated by the addition of guanosine to the
      incubation mixture. The availability of ribose phosphates may be a limiting
      factor for the formation of ribonucleotides from purine bases. The rate of
      incorporation of [(14)C]adenosine into purine ribonucleotides was at least seven-
      to eight-fold higher than that of adenine. The radioactivity in adenine
      ribonucleotides synthesized from adenine and hypoxanthine was about 100- and ten
      fold respectively higher than that in the radioactive guanine ribonucleotides.
      The conversion of inosinate into guanine ribonucleotides was probably limited by
      the amount of inosinate available, and the conversion of adenine ribonucleotides
      into guanine ribonucleotides was probably limited by the activity of adenylate
      deaminase. The rate of catabolism of [(14)C]adenosine was low in comparison with
      its rate of utilization for ribonucleotide synthesis. A fraction of the
      [(14)C]hypoxanthine was catabolized to xanthine and urate. [(14)C]Guanine was
      completely converted into xanthine, mostly by the guanine deaminase that was
      released during incubation of chopped mouse cerebrum.

PMID- 4348170
TI  - Histone phosphatase and cyclic nucleotide-stimulated protein kinase from human
      lymphocytes.
AB  - 1. Extracts of human peripheral blood lymphocytes contained a histone phosphatase
      that catalysed the release of P(i) from phosphorylated whole thymus histone. 2.
      Stimulation of the phosphatase was obtained by concentrations of KCl and NaCl of
      up to 75mm, and by MgCl(2); CaCl(2) inhibited the enzymic activity. 3. In the
      absence of MgCl(2), phosphoenol-pyruvate inhibited histone phosphatase activity;
      this inhibition could be partially reversed by adding MgCl(2) to assays. 4.
      Lymphocyte extracts contained a protein kinase activity which was maximally
      stimulated by 1mum-cyclic AMP (adenosine 3':5'-cyclic monophosphate) or by 0.1mm
      cyclic GMP (guanosine 3':5'-cyclic monophosphate). 5. Incubation of the enzyme
      with histone in the absence of ATP or MgCl(2) resulted in the dissociation of the
      enzyme into a lower-molecular-weight species that was not stimulated by cyclic
      AMP. This effect could be prevented if ATP and MgCl(2) were present in reaction
      mixtures before histone and enzyme were allowed to interact. 6. Cyclic AMP also
      dissociated the kinase into a lower-molecular-weight species. 7. In the presence
      of 1mum-AMP, half-maximal activities were obtained with 0.92mm-MgCl(2), 6.0mum
      ATP and 0.23mg of whole thymus histone/ml.

PMID- 4348169
TI  - Fractionation of nuclei from brain by zonal centrifugation and a study of the
      ribonucleic acid polymerase activity in the various classes of nuclei.
AB  - 1. The nuclei of the cells of the whole rat brain have been fractionated in a B
      XIV zonal rotor with a discontinuous gradient of sucrose. Five fractions were
      obtained. Zone (I) contained neuronal nuclei (70%) and astrocytic nuclei (23%).
      Zone (II) contained astrocytic nuclei (81%) and neuronal nuclei (15%). Zone (III)
      contained astrocytic nuclei (84%) and oligodendrocytic nuclei (15%). Zone (IV)
      contained oligodendrocytic nuclei (92%) and zone (V) contained only
      oligodendrocytic nuclei. 2. The content of DNA, RNA and protein per nucleus was
      determined for each zone. Although the amount of DNA per nucleus is constant
      (7pg) the RNA varies from 4.5 to 2.5pg/nucleus and the protein from 38 to
      17.6pg/nucleus. The neuronal nuclei have the greatest amounts of protein. The
      oligodendrocytic nuclei have the least content of RNA and protein. 3. The effects
      of pH, ionic strength, and Mg(2+) and Mn(2+) concentration on the activity of the
      nuclear system for synthesis in vitro of RNA have been investigated for
      unfractionated nuclei. From these studies a standard set of conditions for the
      assay of nuclear RNA polymerase has been established. 4. The activity of the RNA
      polymerase in each of the zonal fractions has been determined in the presence and
      in the absence of alpha-amanitin. Zone (II) is the most active, followed by zone
      (I). The nuclei of zones (IV) and (V) have comparable activity, which is 40% of
      that of zone (II). 5. The extent of incorporation of each of the four labelled
      nucleoside triphosphates by the nuclei from each zone has been measured. These
      values have been used to calculate the base composition of the RNA synthesized in
      vitro in each class of nucleus. 6. The effect of changes in the condition of
      assay of RNA polymerase in the different classes of nuclei has been investigated.
      Significant differences in the response to concentrations of metal ions and
      ammonium sulphate have been observed. 7. Homopolymer formation in each zone of
      brain nuclei has been determined. The extent of formation of the four
      homopolymers roughly parallels the RNA polymerase activity.

PMID- 4348171
TI  - Release of creatine phosphokinase from muscle. II. Effect of multiple doses of
      polymyxin B or compound 48-80 on increases in plasma enzyme levels.

PMID- 4348172
TI  - Influence of pH on human renin activity with different substrates: role of
      substrate denaturation.

PMID- 4348173
TI  - Two forms of UDPglucose-4-epimerase from mammalian liver.

PMID- 4348174
TI  - Comparative specificity of prenyltransferase of pig liver and pumpkin with
      respect to artificial substrates.

PMID- 4348175
TI  - Partial prufication and properties of the cyclic AMP and the cyclic GMP
      phosphodiesterases of bovine liver.

PMID- 4348176
TI  - Purification of a soluble adenosine 5'-phosphosulphate sulphohydrolase from
      bovine liver.

PMID- 4348177
TI  - Isolation by affinity chromatography of neutral proteinase from Clostridium
      histolyticum.

PMID- 4348179
TI  - Effect of prostaglandins E 1 , E 2  and A 2  on vascular resistance and responses
      to noradrenaline, nerve stimulation and angiotensin in the dog hindlimb.
AB  - 1. The relationship between the vasodilator and inhibitory effects of
      prostaglandin E(1) (PGE(1)), E(2) and A(2) on responses to nerve stimulation,
      noradrenaline and angiotensin was evaluated in the dog hindlimb preparation.2.
      PGE(1) and PGE(2) were equipotent as vasodilators in the hindlimb; however,
      PGE(1) was much more potent as an inhibitor of vasoconstrictor responses to nerve
      stimulation, noradrenaline and angiotensin.3. PGA(2) and PGE(2) were
      approximately equal as inhibitors of vasoconstrictor responses to noradrenaline,
      nerve stimulation and angiotensin; however, PGE(2) was far more potent as a
      vasodilator.4. Since there is no relationship between the vasodilator and
      inhibitory effects of PGE(1), E(2) and A(2), and since the inhibitory effect of
      PGA(2) was present at a time when hindlimb perfusion pressure had returned to
      control value, it is concluded that the inhibitory action is probably not the
      result of a physiological antagonism.5. Since each prostaglandin inhibited
      responses to nerve stimulation and noradrenaline to approximately the same extent
      and responses to angiotensin were also inhibited, it is suggested that these
      agents antagonize vasoconstrictor responses by a nonspecific depressant effect on
      smooth muscle cells.

PMID- 4348178
TI  - The effects of some phosphodiesterase inhibitors on the conductance of the
      perfused vascular beds of the chloralosed cat.
AB  - 1. The vasoactivity of a number of phosphodiesterase inhibitors in the auto
      perfused splanchnic region and hindquarters of the cat have been investigated.2.
      Theophylline, dipyridamole and 4-(3,4-dimethoxybenzyl)-2-imidazolidinone (Ro 7
      2956) and its analogues were more potent vasodilators in the splanchnic region
      than in the hindquarters, whereas papaverine was a potent vasodilator in both
      these vascular beds.3. The vasodilator response to the phosphodiesterase
      inhibitors in the splanchnic region and hindquarters was not susceptible to beta
      adrenoceptor blockade.4. Infusion of dibutyryl cyclic AMP into the superior
      mesenteric artery increased vascular conductance of the splanchnic region. This
      effect was enhanced by Ro 20-1724 in doses below those in which this compound
      affected conductance.5. These results are consistent with the hypothesis that
      accumulation of cyclic AMP in vascular smooth muscle mediates the vasodilator
      response to phosphodiesterase inhibitors.

PMID- 4348180
TI  - The effect of cold storage on the inhibitory action of isoprenaline,
      phenylephrine and nicotine on the mechanical and membranal activities of guinea
      pig taenia caecum.
AB  - 1. The effects of prolonged cold storage on the mechanical and membranal
      responses to stimulation of alpha- and beta-adrenoceptors by phenylephrine and
      isoprenaline, respectively, were studied on the guinea-pig taenia caecum.2. Cold
      storage invariably caused a decrease in the resting membrane potential, and this
      effect was enhanced as the duration of treatment was prolonged.3. After cold
      storage (18 days) the tissue potassium ion content (89.7 +/- 1.7 mmol/kg wet wt.)
      was decreased to 30.5 +/- 1.9 mmol/kg wet wt. whereas that for sodium (69.2 +/-
      1.4 mmol/kg wet wt.) increased to 134.0 +/- 2.3 mmol/kg wet wt.4. In the fresh
      preparations, phenylephrine (1 and 2 muM) caused a cessation of spontaneous
      action potentials, accompanied by hyperpolarization of the membrane and
      relaxation of the muscle. These effects were markedly diminished after 18 days of
      cold storage. Isoprenaline (1 and 2 muM) also blocked the action potentials and
      caused a concomitant muscle relaxation, but in most cases the hyperpolarization
      was not observed. After 14 days of cold storage these mechanical and membranal
      changes associated with isoprenaline treatment were not demonstrable in most
      preparations.5. Nicotine (5 muM and 50 muM) produced a biphasic effect, cessation
      of the action potential, hyperpolarization and subsequent relaxation followed by
      a long lasting depolarization, an accelerated discharge of action potentials and
      an increase in muscle tension. After a few days of cold storage the
      hyperpolarization effect disappeared but the intensity of the long-lasting
      depolarization as well as the contractile effects were increased. After cold
      storage for more than 7 days, nicotine did not affect mechanical or electrical
      activity.6. Dibutyryl 3'5' cyclic AMP (1 muM to 500 muM) failed to affect the
      mechanical and electrical activities of taenia caecum.7. Phenylephrine and
      isoprenaline had no effect on the high potassiumdepolarized taenia.8. These
      observations suggest that the electro-mechanical effect of an alpha-adrenoceptor
      stimulant on the guinea-pig taenia caecum is more resistant to cold treatment
      than that of a beta-adrenoceptor stimulant. This inhibitory system of stimulation
      of both a- and 8-receptors of guinea-pig taenia caecum may react by different
      mechanisms. The results also demonstrate that cold storage itself changes the
      membrane permeability to ions and the tissue ion content (Na+ and K+) of smooth
      muscle of guinea-pig taenia caecum.

PMID- 4348181
TI  - Augmentation of drug-induced blood pressure increases in rats by amorbarbital.
AB  - The effects of amobarbital anaesthesia on blood pressure responses to angiotensin
      and noradrenaline were determined in rats with chronically implanted venous and
      aortic catheters. Responses were tested twice on the same day in each rat, first
      in the conscious state and then during anaesthesia. Blood pressure rises produced
      by noradrenaline and angiotensin were larger when the rats were anaesthetized
      with amobarbital than when they were conscious. This enhancement was not
      characteristic of general anaesthesia since urethane, instead of enhancing,
      depressed the pressor responses.Blockade of acetylcholine receptors with atropine
      also increased the response to pressor drugs. However, amobarbital in anaesthetic
      doses did not affect the response to acetylcholine, indicating that removal of
      compensatory parasympathetic reflexes was not a major cause of its enhancing
      effect. The effects of amobarbital on arterial pressure and heart rate were
      similar to those of the ganglion blocking drug pentolinium. When pressor
      responses were increased by amobarbital, autonomic ganglia were depressed as
      indicated by the loss of the response to nicotine. These findings suggest that
      amobarbital enhances blood pressure responses to noradrenaline and angiotensin by
      blocking autonomic ganglia.

PMID- 4348182
TI  - The effect of N6,O2'-dibutyryl adenosine 3':5'-cyclic monophosphate on
      noradrenaline synthesis in isolated superior cervical ganglia.

PMID- 4348183
TI  - Studies on the mode of action of cyclic 3'5'-AMP and prostaglndin E 2  on rat
      gastric acid secretion and mucosal blood flow.

PMID- 4348184
TI  - The effect of some synthetic analogues of ACTH on the metabolism of biogenic
      amines in the rat brain.

PMID- 4348185
TI  - Estimation of angiotensin II blood concentrations in hypertensive rats.

PMID- 4348187
TI  - Effect of chlorpromazine on REM rebound in normal volunteers.

PMID- 4348188
TI  - [Functional differentiation of anterior pituitary cells].

PMID- 4348186
TI  - Recurrent hyperkalaemia due to selective aldosterone deficiency: correction by
      angiotensin infusion.
AB  - A patient with recurrent weakness and blurring of consciousness associated with
      hyperkalaemia due to aldosterone deficiency is reported. The plasma
      concentrations of renin, angiotensin II, and aldosterone were low and did not
      increase during sodium deprivation. Blood angiotensin I was also low while renin
      substrate concentration was normal. Infusion of angiotensin produced a distinct
      rise in plasma aldosterone. The patient was treated successfully with
      fludrocortisol.The results support the concept that the renin-angiotensin system
      is an important regulator of aldosterone secretion and that in the syndrome of
      acquired selective hypoaldosteronism the primary abnormality may be a deficiency
      of renin. It is suggested that a selective lack of aldosterone should be
      considered in all cases of otherwise unexplained hyperkalaemia.

PMID- 4348190
TI  - [Feto-placental relation in fetal endocrine function].

PMID- 4348189
TI  - [Adrenal cortex stimulating hormone (ACTH)].

PMID- 4348191
TI  - Evidence that pepsitensin is angiotensin I.

PMID- 4348192
TI  - Selective suppression of rapid eye movement sleep (REM) by fusaric acid, an
      inhibitor of dopamine- -oxidase.

PMID- 4348193
TI  - Electron microscopic observations of neocarzinostatin treated Burkitt lymphoma
      cells.

PMID- 4348194
TI  - The finding of viral particles in spontaneous mammary adenocarcinoma in rats.

PMID- 4348195
TI  - Co-existence of a guanidine-dependence and of a thiopyrimidine dependence in the
      same strain of poliovirus.

PMID- 4348196
TI  - Preparation and biological activity of some anthyridine derivatives.

PMID- 4348197
TI  - [The effect of sodium gallate on adenoreceptors of smooth muscles].

PMID- 4348198
TI  - Adenoviral infection in foals.

PMID- 4348199
TI  - Cerebral malformation in fetal lambs from a bluetongue-enzootic flock.

PMID- 4348201
TI  - Properties of 5-phosphoribosyl-1-pyrophosphate amidotransferase from human
      lymphoblasts.

PMID- 4348200
TI  - Characterization of the 4-acetamido-4,6-dideoxyhexoses from Escherichia coli
      strains.

PMID- 4348202
TI  - Human glutamine phosphoribosylpyrophosphate amidotransferase. Kinetic and
      regulatory properties.

PMID- 4348203
TI  - Genetic regulation of aryl hydrocarbon hydroxylase induction. V. Specific changes
      in spin state of cytochrome P 450  from genetically responsive animals.

PMID- 4348204
TI  - Dissociation and activation of adenosine 3',5'-monophosphate-dependent and
      guanosine 3',5'-monophosphate-dependent protein kinases by cyclic nucleotides and
      by substrate proteins.

PMID- 4348205
TI  - Protein kinase modulator from lobster tail muscle. I. Stimulatory and inhibitory
      effects of the modulator on the phosphorylation of substrate proteins by
      guanosine 3',5'-monophosphate-dependent and adenosine 3',5'-monophosphate
      dependent protein kinases.

PMID- 4348206
TI  - Protein kinase modulator from lobster tail muscle. II. Effects of the modulator
      on holoenzyme and catalytic subunit of guanosine 3',5'-monophosphate-dependent
      and adenosine 3',5'-monophosphate-dependent protein kinases.

PMID- 4348207
TI  - Phenylalanine hydroxylase in cultured hepatoxytes. I. Hormonal control of enzyme
      levels.

PMID- 4348208
TI  - Separate oxidase and reductase reaction sites on cytochrome c demonstrated with
      purified site-specific antibodies.

PMID- 4348209
TI  - Insulin-receptor interaction in the obese-hyperglycemic mouse. A model of insulin
      resistance.

PMID- 4348210
TI  - Studies on the mechanism of action of uridine diphosphate galactose 4-epimerase.
      II. Substrate-dependent reduction by sodium borohydride.

PMID- 4348211
TI  - Enzyme secretion mediated by the epinephrine  -receptor in rat parotid slices.
      Factors governing efficiency of the process.

PMID- 4348212
TI  - Potassium release mediated by the epinephrine  -receptor in rat parotid slices.
      Properties and relation to enzyme secretion.

PMID- 4348213
TI  - Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by
      5-fluorouracil and 5-fluorouridine.

PMID- 4348214
TI  - The mechanism of the water expulsion vesicle of the ciliate Tetrahymena
      pyriformis.
AB  - Analysis of high-speed (150 frames/sec) cinematographs of the filling and
      expulsion of the water expulsion vesicle of Tetrahymena pyriformis shows that the
      vesicle fills as water is pumped into it by contractions of at least four
      ampullary sacs which are continuous with the endoplasmic reticulum. When filled,
      the vesicle is pressed against its two excretory pores by cyclotic movements of
      the cytoplasm. This pressure closes the apertures of the ampullae, preventing
      backflow from the vesicle into them, and also spreads the pellicle of and at the
      pore, thereby stretching and rupturing the pore-sealing membrane. The vesicle is
      then invaginated by the cytoplasmic pressure, driving fluid out of the pore. The
      pore-sealing membrane then reforms, apparently by constriction, and the vesicle
      is again filled. Electron micrographs show that crisscrossed pore-microtubules
      extend from the pore to the openings of the ampullae, anchoring the vesicle in
      place. Each pore is surrounded by a stack of at least 11 ring-microtubules, to
      which the anchoring pore-microtubules are attached. The pore-microtubules appear
      to exert tension which assists in spreading the pore, aiding cyclotic pressures
      in rupturing the pore-sealing membrane. A possible mechanism for the cyclotic
      pressure and ampullary contraction is proposed.

PMID- 4348215
TI  - Nematosomes in the rat trigeminal ganglion.

PMID- 4348217
TI  - Susceptibility of mammalian (hamster) cell culture to infection with cellular and
      cell-free type II leukosis (Marek's disease) virus.

PMID- 4348216
TI  - Ultrastructural studies of cell-virus interaction in reptilian cell lines. I.
      Intramitochondrial viruses in "C-type" virus-producing VSW cells.

PMID- 4348218
TI  - Transplantation immunity to simian virus 40-transformed cells in tumor-bearing
      mice. I. Development of cellular immunity to simian virus 40 tumor-specific
      transplantation antigens during tumorigenesis by transplanted cells.

PMID- 4348219
TI  - Transplantation immunity to simian virus 40-transformed cells in tumor-bearing
      mice. II. Evidence for macrophage participation at the effector level of tumor
      cell rejection.

PMID- 4348220
TI  - Enhanced tumor growth in animals pretreated with complete Freund's adjuvant.

PMID- 4348221
TI  - Effect of treatment of C57BL-6 mice with the methanol extraction residue fraction
      of BCG on leukemogenesis induced by the radiation leukemia virus.

PMID- 4348222
TI  - Activation of a type-C RNA virus from tumors induced by rat kidney cells
      transformed by a chemical carcinogen.

PMID- 4348223
TI  - Preparation of pure cultures of tumor macrophages.

PMID- 4348224
TI  - Morphogenesis of C-type and A-type particles in cells infected by an arbovirus.

PMID- 4348225
TI  - Effect of CCNU (NSC-79037) on bronchogenic carcinoma.

PMID- 4348226
TI  - Brain tumors induced by Rous sarcoma virus, Schmidt-Ruppin strain. 3. Morphology
      of brain tumors induced in adult mice.

PMID- 4348227
TI  - A case of leprous nodular interstitial myositis.

PMID- 4348228
TI  - Autoxidation of polyunsaturated fatty esters on silica.

PMID- 4348229
TI  - Malignant lymphoma. 1.

PMID- 4348230
TI  - [Recovery in neurosurgical diseases].

PMID- 4348231
TI  - Parasympathetic control of the heart.

PMID- 4348232
TI  - The PARA-adenoviruses.

PMID- 4348233
TI  - [Changes in some histochemical reactions in the wall of gallbladder in diseases
      of biliary system].

PMID- 4348234
TI  - [Histochemical studies of gastric mucosa in patients with chronic cholecystitis].

PMID- 4348235
TI  - [Radiation oxidation of cytochrome C in aqueous solution].

PMID- 4348237
TI  - Annular nucleolus in Leydig cells of mouse.

PMID- 4348236
TI  - [Study of primary and secondary paramagnetic formations in gamma-irradiated
      single-stranded DNA].

PMID- 4348238
TI  - Electron microscopic study on the thyroid gland of the salamander Hynobius
      nebulosus in the breeding season. I. Observation under normal conditions.

PMID- 4348239
TI  - Electron microscopic study on the thyroid gland of the salamander Hynobius
      nebulosus in the breeding season. II. Observation under experimental conditions.

PMID- 4348241
TI  - [Pleomorphic adenoma of the parotid gland in a child].

PMID- 4348240
TI  - Synaptic junction development in the spinal cord of an amphibian embryo: an
      electron microscope study.

PMID- 4348243
TI  - Ultrastructural study of virilizing adrenocortical adenoma.

PMID- 4348242
TI  - The effect of enzymes on extracellular connective tissue components in the
      developing chick aorta.

PMID- 4348244
TI  - Enterovirus surveillance following a community-wide oral poliovirus vaccination
      program: a seven-year study.

PMID- 4348245
TI  - Acute respiratory disease in military trainees: the adenovirus surveillance
      program, 1966-1971.

PMID- 4348246
TI  - Immunoglobulin response and viremia in dengue-vaccinated gibbons repeatedly
      challenged with Japanese encephalitis virus.

PMID- 4348247
TI  - Significance and treatment of lymph node metastases of malignant mucous and
      salivary gland tumors.

PMID- 4348248
TI  - Superior vena caval syndrome: scintiphotographic evaluation of response to
      radiation therapy.

PMID- 4348249
TI  - Inferior phrenic artery collateralization in hepatic artery occlusion.

PMID- 4348250
TI  - Mixed mesodermal sarcoma of the uterus.

PMID- 4348251
TI  - An attempt to clarify the immunobiological significance of Mott's cells.

PMID- 4348252
TI  - Oxidative phosphorylation in intact bacteria.

PMID- 4348253
TI  - [Accidental isolations of latent ectromelia in laboratory white mice in the
      course of studies of arboviruses].

PMID- 4348254
TI  - Inhibition of poliovirus multiplication by a normal horse serum. I.
      Characterization of virus-inhibitor interaction.

PMID- 4348255
TI  - The pressor effect of angiotensin II in pregnant sheep.

PMID- 4348256
TI  - Genetic and biochemical studies of the adrenal lipid depletion phenotype in mice.

PMID- 4348257
TI  - Genetic relationships between the multiple alcohol dehydrogenases of maize.

PMID- 4348258
TI  - Biosynthesis of geraniol and nerol and beta-D-glucosides in Pelargonium
      graveolens and Rosa dilecta.
AB  - 1. 3R-[2-(14)C]Mevalonate was incorporated into geranyl and neryl beta-d
      glucosides in petals of Rosa dilecta in up to 10.6% yield, and the terpenoid part
      was specifically and equivalently labelled in the moieties derived from
      isopentenyl pyrophosphate and 3,3-dimethylallyl pyrophosphate. A similar
      labelling pattern, with incorporations of 0.06-0.1% was found for geraniol or
      nerol formed in leaves of Pelargonium graveolens The former results provide the
      best available evidence for the mevalonoid route to regular monoterpenes in
      higher plants. 2. Incorporation studies with 3RS-[2-(14)C,(4R)-4-(3)H(1)]
      mevalonate and its (4S)-isomer showed that the pro-4R hydrogen atom of the
      precursor was retained and the pro-4S hydrogen atom was eliminated in both
      alcohols and both glucosides. These results suggest that the correlation of
      retention of the pro-4S hydrogen atom of mevalonate with formation of a cis
      substituted double bond, such as has been found in certain higher terpenoids,
      does not apply to the biosynthesis of monoterpenes. It is proposed that either
      nerol is derived from isomerization of geraniol or the two alcohols are directly
      formed by different prenyltransferases. Possible mechanisms for these processes
      are discussed. 3. The experiments with [(14)C,(3)H]mevalonate also show that in
      these higher plants, as has been previously found in animal tissue and yeast, the
      pro-4S hydrogen atom of mevalonate was lost in the conversion of isopentenyl
      pyrophosphate into 3,3-dimethylallyl pyrophosphate.

PMID- 4348259
TI  - Isolation and characterization of membranes from normal and transformed tissue
      culture cells.
AB  - Homogenates of baby-hamster kidney cells and rat embryo fibroblasts prepared by
      nitrogen cavitation contain a small population of slowly sedimenting mitochondria
      or mitochondrial fragments, which contaminate the microsomal fraction. This
      appears to limit the resolution of surface membrane and endoplasmic reticulum on
      magnesium-containing dextran gradients. The microsomal material and mitochondria
      can, however, be completely separated on a 10-60% (w/w) sucrose zonal gradient
      containing a 30% sucrose plateau. On magnesium-containing dextran gradients this
      mitochondria-free microsomal material can be resolved into at least two surface
      membrane fractions and at least two endoplasmic reticulum fractions. Comparison
      of polyoma virus-transformed and normal baby-hamster kidney cells reveals some
      interesting differences in their microsomal fractionation patterns and the
      characteristics of the Na(+)/K(+)-Mg(2+) adenosine triphosphatase of their
      surface membranes, in particular a tenfold lower K(m) in the virus-transformed
      cells. The fractionation patterns of normal and spontaneously transformed rat
      embryo fibroblasts are also briefly discussed, particularly in relation to the
      significance of the observation that both the surface membrane and endoplasmic
      reticulum from these cells can be subfractionated.

PMID- 4348260
TI  - The regulation of rabbit liver fructose 1,6-diphosphatase activity by
      phospholipids in vitro.

PMID- 4348261
TI  - Evidence for modification of protein phosphorylation by cytokinins.
AB  - Kinetin stimulated phosphorylation of protein in floated Chinese-cabbage leaf
      discs, but inhibited protein phosphorylation in nuclei+chloroplast extracts from
      Chinese-cabbage or tobacco leaves. Kinetin also inhibited protein phosphorylation
      in isolated tobacco nuclei or nuclei from carrot secondary-phloem tissue.
      Purified Chinese-cabbage leaf ribosomes exhibited protein kinase activity which
      was inhibited by kinetin and zeatin. The ribosome-associated kinase responded to
      kinetin and zeatin differently from that associated with nuclei+chloroplast
      preparations. Protein phosphorylation in vitro was not affected by adenosine
      3':5'-cyclic monophosphate, indol-3-ylacetic acid or gibberellic acid. It was
      only inhibited by N(9)-unsubstituted purines, among which the known cytokinins
      were the most effective inhibitors. The results are discussed in relation to
      possible similarities between the effects of cytokinins in plant tissues and the
      effects of adenosine 3':5'-cyclic monophosphate in animal tissues. Both compounds
      appear to modify the activity of protein kinases and both affect many different
      cellular processes.

PMID- 4348262
TI  - Isolation and characterization of lipoprotein B from high-density human serum
      lipoproteins.
AB  - 1. Lipoprotein B from female Lp(a)-lipoprotein-negative serum was isolated from
      the fraction of density 1.073-1.125 by using immunoadsorbent; 2.5mg of freeze
      dried material was obtained from 100ml of serum from a fasting patient. 2. The
      hydrated density of this lipoprotein was found to be 1.084g/cm(3). A flotation
      rate F(1.200) of 9.4 and lipid/protein ratio 1.40 were found, similar to that of
      high-density (d 1.073-1.125) lipoprotein preparations. 3. From immunochemical and
      electrophoretic studies of the intact and totally delipidized lipoprotein B it
      was concluded that this lipoprotein represents a separate family within the high
      density range of human serum lipoproteins. 4. The possibility that the isolated
      lipoprotein B is an artifact created by the isolation procedure is discussed.

PMID- 4348264
TI  - Can Culex pipiens fatigans or Aedes aegypti spread smallpox? A preliminary
      report.

PMID- 4348265
TI  - Proteolytic activity of Entamoeba histolytica. 1. Detection of enzyme by
      photographic film band.

PMID- 4348263
TI  - Development of the activities of enzymes of the isoprenoid pathway during early
      stages of pea-seed germination.
AB  - The activities of individual enzymes of the isoprenoid pathway from mevalonate
      kinase to squalene synthetase in homogenates of seeds germinated up to 32h were
      assayed. Changes in the activity of each enzyme were observed and compared with
      the activity at the 2h germination stage. Activities of alkaline phosphatase and
      fructose 1,6-diphosphate aldolase were similarly measured to provide a reference
      for changes in the general metabolic activity of seeds during imbibition of
      water. Water uptake reached a plateau after 12h. The reference enzymes almost
      doubled in activity between 2 and 8h and thereafter their activities steadily
      declined. All of the enzymes of the isoprenoid pathway increased in activity
      between 2 and 6h and, thereafter, with the exception of the prenyltransferase,
      their activities remained relatively constant. With the prenyltransferase
      activity the initial increase was followed by a short plateau between 6 and 9h
      and then a second increase to a maximum between 14 and 16h. After 16h the
      activity declined. The relative activities of the isoprenoid enzymes at 16h of
      germination were mevalonate kinase>phosphomevalonate kinase>pyrophosphomevalonate
      decarboxylase approximately isopentenyl pyrophosphate isomerase>squalene
      synthetase>isopentenyl pyrophosphate/dimethylallyl pyrophosphate
      prenyltransferase. The finding that the prenyltransferase may be the rate
      limiting enzyme in squalene synthesis from mevalonate is discussed in relation to
      regulation of isoprenoid synthesis during pea-seed germination.

PMID- 4348266
TI  - The identification of the enzymes that catalyse the oxidation of glyoxylate to
      oxalate in the 100000 g supernatant fraction of human hyperoxaluric and control
      liver and heart tissue.

PMID- 4348267
TI  - [Formation and transformation of glucose, 2-deoxyglucose and 2-deoxyribose
      radicals in gamma-irradiated frozen aqueous solutions].

PMID- 4348268
TI  - [Modeling ecological and population relations in experiments with bacterial
      cultures].

PMID- 4348269
TI  - [Changes in the Na +, K + -ATPase and n-nitrophenylphosphatase activity of
      retinal outer segments during illumination].

PMID- 4348270
TI  - [Chemotherapy and drug resistance of pathogens].

PMID- 4348271
TI  - [Effects of toxic fumes produced by soldering operations on the human body. I. A
      study of intoxication by nitrous vapors, using EPR spectrometry].

PMID- 4348272
TI  - Electron microscopic evidence of the subviral oncogenic particles (virosomes)
      isolated from the mitochondria of Rous sarcoma cells.

PMID- 4348273
TI  - Classroom approach teaches patients independence skills.

PMID- 4348274
TI  - Hospital takes group therapy to released alcoholics in distant community.

PMID- 4348275
TI  - A drug unit for life-style change: the Tellurian community.

PMID- 4348276
TI  - The production of vesicular stomatitis virus by antigen- or mitogen-stimulated
      lymphocytes and continuous lymphoblastoid lines.
AB  - A variety of lymphoid cell populations were examined in terms of their ability to
      replicate vesicular stomatitis virus (VSV), a lytic, RNA-containing virus
      maturing at the cell surface. The number of cells capable of producing VSV was
      estimated in terms of infectious centers by the virus plaque assay (VPA), and
      morphologically by electron microscopy (EM). The lymphoid cells examined in this
      study included: (a) lymph node cells from delayed hypersensitive guinea pigs
      stimulated by specific antigen, (b) mouse spleen cells activated by selective
      bone marrow-derived (B) cell and thymus derived (T) cell mitogens, and (c) cells
      of human and murine continuous lymphoblastoid or lymphoma lines. In unstimulated
      cultures of guinea pig lymph node cells there is a background of approximately 1
      in 1,000 cells which produces VSV; in purified protein derivative (PPD)
      stimulated cultures the number of cells producing virus was 1.6% in the VPA and
      1.9% by EM. These cells were large lymphocytes with some morphological features
      of transformed lymphocytes but were not typical blast cells. A few macrophages
      were associated with virus in both stimulated and control cultures. These
      observations indicate that (a) cells responsive to antigens, as detected by a
      marker virus, were lymphocytes; (b) cells other than lymphocytes (macrophages)
      were capable of replicating VSV even without antigenic stimulation; and (c) the
      correlation of results obtained by VPA and morphologic examination was usually
      quite good. Of the total number of mouse spleen cells stimulated with
      concanavalin (Con A), a T cell mitogen, 4.5 (EM)-5.7% (VPA) were associated with
      VSV. These were characteristic transformed lymphocytes, similar to
      phytohemagglutinin (PHA)-stimulated human lymphocytes. In contrast Escherichia
      coli lipopolysaccharide (LPS)-treated mouse spleen cultures contained lower
      numbers of virus plaque-forming cells. The majority of such cells associated with
      virus displayed extensive rough endoplasmic reticulum. Two cultured murine
      lymphomas containing lymphocytes with the theta surface marker (L5178Y and EL-4)
      showed a 15-100-fold higher incidence of virus-producing cells than leukemias
      (L1210 and C57Bl/6) which did not carry this marker. Similarly, the L2C guinea
      pig leukemia, a known B cell leukemia, yielded a low percent of virus plaque
      forming cells (<2%). However, MOPC-104, a plasma cell tumor presumed to be of B
      cell origin, was found to be an efficient virus producer. There was a wide
      variation in the efficiency of VSV replication among human lymphoblastoid lines.
      One line, Wil-2, produced 80% infectious centers after 24 h of exposure to VSV,
      and all cells were associated with virus at the EM level. The relationship
      between the virus-producing cells and different lymphocyte subpopulations as well
      as the efficiency of the two assays for studying virus-producing lymphocytes is
      discussed.

PMID- 4348278
TI  - Induction of arginase activity with the Shope papilloma virus in tissue culture
      cells from an argininemic patient.
AB  - Inoculation of the Shope virus in tissue cultures of human fibroblasts from a
      patient with a deficiency of the enzyme arginase results in an induction of
      arginase activity, apparently virus coded.

PMID- 4348277
TI  - The effect of Bordetella pertussis on lymphocyte cyclic AMP metabolism.
AB  - Bordetella pertussis culture fractions produce decreased metabolic responses to
      isoproterenol and epinephrine in mice and rats, suggesting the possibility of
      systemic beta adrenergic blockade. The present study was undertaken to elucidate
      the mechanism of the alteration in adrenergic responsiveness and to clarify its
      relationship to other biological effects of the organism. Lymphocytes were
      selected as a suitable tissue because of the marked alteration in lymphocyte
      distribution in pertussis-treated mice and rats, suggesting a change in the
      surface properties of these cells. Human peripheral blood lymphocytes, purified
      by nylon fiber chromatography, were studied. In short incubation experiments (20
      min or less) B. pertussis did not alter the cyclic AMP response to isoproterenol,
      prostaglandin E (PGE(1)), or methacholine. However, when cells were preincubated
      with B. pertussis for 90 min at 37 degrees C, the responses to all three agents
      were markedly inhibited. Although these observations provide direct confirmation
      of the ability of B. pertussis to inhibit catecholamine responsiveness, the fact
      that PGE(1) and methacholine responses were also inhibited suggests that blockade
      at the level of the beta adrenergic receptor is doubtful. The inhibitory activity
      was localized in a nondialyzable, protein-rich fraction that is precipitated from
      B. pertussis culture fluid by ammonium sulfate at 90% of saturation. The bulk of
      the activity was obtained in the load volume after 50,000 g centrifugation in a
      cesium chloride gradient, density 1.2-1.5 (fraction 4). Fraction 4 produced a
      change in lymphocyte hormonal responsiveness at concentrations as low as 5 ng/ml.
      The relationship between cyclic AMP inhibitory activity in isolated human cells
      and leukocytosis-producing activity in intact mice was studied. The two
      activities seemed to parallel one another quite closely until the final Sephadex
      G-150 fractionation step, in which the two activities were obtained in the same
      column fraction, but a greater recovery of the leukocytosis-producing activity
      was obtained. Additional purification will be required to establish conclusively
      whether the same macromolecule is responsible for both activities. The
      availability of a bacterial product that markedly inhibits cyclic AMP
      accumulation in purified lymphocytes may help to clarify the role of cyclic AMP
      in lymphocyte activation by antigen and nonspecific mitogens.

PMID- 4348279
TI  - Relation of chromosome 4 (linkage group 8) to murine leukemia virus-associated
      antigens of AKR mice.
AB  - Genes specifying or controlling the expression of G(IX) (cell surface), GCSA
      (cell surface), and gs (internal viral) antigens are located in chromosome 4
      (linkage group [LG] VIII) of the AKR mouse. All three antigens may exhibit
      mendelian inheritance, mice being antigen positive or antigen negative, but each
      may also appear in leukemic cells of mice whose inherited genotype was antigen
      negative. The G(IX)-determining gene in LG VIII of AKR mice apparently is
      equivalent to Gv-1, which determines expression of the same antigen in 129 strain
      mice, but which in the latter strain is located in LG IX. As the estimated
      distance of Gv-1 from H-2 in 129 mice is considerable (37 units) further tests
      are now indicated to assess the possibility of pseudolinkage in this case. The Fv
      1 locus, also located in LG VIII, influences the mouse's titer of MuLV, and might
      thereby be thought to regulate the G(IX) and gs phenotypes of AKR backcross
      segregants. But the data indicate a discrete LG VIII locus for G(IX), since
      expression of this antigen is mendelian and independent of infectious virus
      titer. Since the G(IX) and GCSA phenotypes of AKR backcross segregants were
      invariably concordant, these two antigens must be specified or controlled by
      closely linked genes, and the latter also is presumably independent of virus
      titer. The question as to what extent expression of gs antigen in the segregants
      is secondary to virus production is undecided.

PMID- 4348280
TI  - Radiographic and physiologic patterns among workers engaged in manufacture of
      asbestos cement products: a preliminary report.

PMID- 4348281
TI  - Antagonism of peripheral and central effects of angiotensin II by (1-sarcosine, 8
      isoleucine)angiotensin II.

PMID- 4348282
TI  - Inhibition of lysosomal enzyme release by adenosine 5' triphosphate and N 6 ,O 2 
      dibutyryl cyclic 3',5'-adenosine monophosphate.

PMID- 4348283
TI  - Metabolic factors involved in the interaction between pyrazole and butane-1,4
      diol and 4-hydroxybutyric acid.

PMID- 4348284
TI  - Effects of denervation and lack of calcium on the action of Latrodectus venom on
      rat sympathetic ganglion.

PMID- 4348285
TI  - Effect of mineralocorticoid agonists and antagonists on binding of  3 H
      aldosterone to adrenalectomized rat kidney plasma membranes.

PMID- 4348286
TI  - The inhibitory effects of theophylline feeding on gluconeogenic enzymes in rat
      liver.

PMID- 4348287
TI  - Stimulation of mitochondrial DNA synthesis in HeLa cells by Herpes simplex virus.

PMID- 4348288
TI  - Cyclic-AMP binding sites on the cell surface of thymic lymphocytes.

PMID- 4348289
TI  - Aortic proline hydroxylase in hypoxia induced arteriosclerosis in rabbits.

PMID- 4348290
TI  - Isosmotic intracellular regulation and redox changes in the respiratory chain
      components of Callinectes sapidus isolated muscle fibers.

PMID- 4348291
TI  - Increased phosphofructokinase concentration in hepatoma 3924-A: enzymic and
      immunological evidence.

PMID- 4348292
TI  - Hepatic surgery.

PMID- 4348293
TI  - Association of cervical cytomegaloviruses with venereal disease.

PMID- 4348294
TI  - Hepatocyte specificity for  -foetoprotein production.

PMID- 4348295
TI  - A study on the levels of nucleic acids, protein and phosphatases in normal and X
      irradiated guinea pigs.

PMID- 4348296
TI  - [Animal experiments on the effect of vitamin A on Walker carcinoma of the rat].

PMID- 4348297
TI  - [Presence of enteric viruses in soil].

PMID- 4348298
TI  - [Granular cell myoblastoma].

PMID- 4348299
TI  - [Vitamin D. Fascinating research results in relation to the anti-epileptics].

PMID- 4348300
TI  - Interactions of components of human rhinovirus type 2 with Hela cells.

PMID- 4348301
TI  - Ribonucleases of Rous sarcoma virus.

PMID- 4348302
TI  - The nucleic acid of an SV40-like virus isolated from a patient with progressive
      multifocal leukoencephalopathy.

PMID- 4348303
TI  - Simian virus 40 DNA integration within the genome of virus-transformed mammalian
      cells.

PMID- 4348304
TI  - An analysis of the physical and chemical factors involved in the reactivation of
      neutralized poliovirus by the method of freezing and thawing.

PMID- 4348305
TI  - Host cell DNA synthesis as a possible factor in the enhancement of replication of
      human adenoviruses in simian cells by SV40.

PMID- 4348306
TI  - Adenosine 3',5'-cyclic monophosphate regulation of chloramphenicol
      acetyltransferase synthesis in vitro from P1CM DNA.

PMID- 4348307
TI  - Polyacrylamide gel electrophoresis of fowlpox and vaccinia virus proteins.

PMID- 4348308
TI  - Studies of SV40 DNA. VI. Cleavage of SV40 DNA by restriction endonuclease from
      Hemophilus parainfluenzae.

PMID- 4348309
TI  - Morphological aspects of the hypothalamic-hypophyseal system. IV. Medial basal
      hypothalamus. An experimental morphological study.

PMID- 4348310
TI  - Ultrastructural aspects of the nucleus infundibularis dorsalis in the caudal
      hypothalamus of Xenopus laevis.

PMID- 4348311
TI  - Profound cystic colitis. Colitis cystica profunda.

PMID- 4348312
TI  - Adenosine 3',5'--cyclic monophosphate dependent protein kinase and phosphoprotein
      phosphatase activities in rat islets of Langerhans.

PMID- 4348313
TI  - The preparation of a modified GTP-sepharose derivative and its use in the
      purification of dihydroneopterin triphosphate synthetase, the first enzyme in
      folate biosynthesis.

PMID- 4348314
TI  - Effect of histamine of lipolysis and adenosine 3',5'-monophosphate levels in
      canine adipose tissue.

PMID- 4348315
TI  - The mechanism of the nicotinamide adenine dinucleotide stimulation of lipid
      phosphorylation in a rat liver microsome-cytosol system.

PMID- 4348316
TI  - Effect of phospholipids on lipoprotein lipase activation in vitro.

PMID- 4348317
TI  - Cell density dependent glycolipids in NILz hamster cells, derived malignant and
      transformed cell lines.

PMID- 4348318
TI  - Lipid composition, Ca 2+  uptake and Ca 2+ -stimulated ATPase activity of
      sarcoplasmic reticulum of the cardiomyopathic hamster.

PMID- 4348319
TI  - Production of cholinesterase by Pseudomonas aeruginosa, its regulation by glucose
      and cyclic AMP and inhibition by antiserum.

PMID- 4348320
TI  - Corticosteroid binding macromolecules in the nucleus and cytosol of rat thymus
      cells.

PMID- 4348321
TI  - [Estradiol-17  receptors in the liver of chicken and the amphibian Discoglossus
      pictus].

PMID- 4348322
TI  - Endogenous production of steroids by subcellular fractions from total rat testis
      and from isolated interstitial tissue and seminiferous tubules.

PMID- 4348323
TI  - Involvement of thiol enzymes in the lysosomal breakdown of native and denatured
      proteins.

PMID- 4348325
TI  - [Effect of ionizing radiation on copper complexes with amino acids].

PMID- 4348324
TI  - [EPR study of photosensitized reactions in peptides].

PMID- 4348326
TI  - Isolation of oncornaviruses from chemically induced murine leukemias.

PMID- 4348328
TI  - [Variations in oncogenicity of the adenovirus transformed cell line Ad12-C3H
      under conditions of immunosuppression].

PMID- 4348327
TI  - [The production of an enhancing factor].

PMID- 4348329
TI  - NADH-cytochrome C reductase activity of antigen-stimulated macrophages.

PMID- 4348330
TI  - [The effect of alpha-staphylococcal toxin on in vitro cultured cells. I.
      Cytochemical study].

PMID- 4348332
TI  - Submandibular duct lithiasis associated with a mixed salivary gland tumor. A case
      report.

PMID- 4348331
TI  - Phospholipids in artificially induced muscular dystrophy of calves.

PMID- 4348333
TI  - Proteinaceous precipitate in nodular (follicular) lymphomas.

PMID- 4348334
TI  - Correlation of suspicious mammograms and x-rays of breast biopsies during
      surgery. Results in 60 cases.

PMID- 4348335
TI  - Sclerosing stromal tumors of the ovary.

PMID- 4348336
TI  - Carcinoma of the kidney in a 15-year-old boy. Unusual histologic features with
      formation of microvilli.

PMID- 4348337
TI  - Primary thymic seminoma--a neoplasm ultrastructurally similar to testicular
      seminoma and distinct from epithelial thymoma.

PMID- 4348338
TI  - The intracellular site of surfactant synthesis. Autoradiographic studies on
      murine and avian lung explants.

PMID- 4348339
TI  - Ultrastructure of the renal arterial bifurcation of rabbits.

PMID- 4348340
TI  - Enzyme activity in the fluid of the human ovarian follicle.

PMID- 4348342
TI  - Cinemicrography of pyrene perchlorate crystal formation by electrolysis.

PMID- 4348341
TI  - [Pronator teres syndrome and brachialgia].

PMID- 4348343
TI  - Renal sodium- and potassium-activated adenosine triphosphatase and sodium
      reabsorption in the hypothyroid rat.
AB  - The relationship between net tubular reabsorption of sodium and renal microsomal
      sodium- and potassium-activated adenosine triphosphatase (Na-K-ATPase) was
      evaluated in hypothyroid and hyperthyroid rats and in age-matched euthyroid
      controls. Tubular sodium reabsorption per gram of kidney was lower in
      thyroidectomized rats than in controls (186+/-14 vs. 246+/-12 mueq/min; P <
      0.005) and was accompanied by a quantitatively similar reduction in Na-K-ATPase
      specific activity (49.4+/-2.4 vs. 65.8+/-2.3 mumol inorganic phosphate (P(t))/mg
      protein per h; P < 0.001). This decrement was present in both cortex and outer
      medulla, and was limited to Na-K-ATPase since other representative enzymes not
      involved in sodium transport (magnesium-dependent adenosine triphosphatase [Mg
      ATPase], glucose-6-phosphatase, 5'-nucleotidase) remained unchanged or increased
      in the hypothyroid animals. Conversely, Na-K-ATPase rose when sodium reabsorption
      increased in euthyroid rats treated with triiodothyronine. Subsequent experiments
      were performed to determine to what extent the decrease in Na-K-ATPase is due to
      lack of thyroid hormone per se or to an adaptive response to decreased
      reabsorptive sodium load. Triiodothyronine in concentrations of 10(-12) to 10(-5)
      M had no effect in vitro on microsomal Na-K-ATPase of either thyroidectomized or
      euthyroid rats. When hypothyroid rats were uninephrectomized or treated with
      methylprednisolone, sodium reabsorption per gram kidney increased markedly and
      was similar to that of intact controls. Despite persistence of the hypothyroid
      state, Na-K-ATPase specific activity also increased to levels not significantly
      different from euthyroid animals. These data suggest that decreased tubular
      sodium transport is a major determinant of the reduction in renal Na-K-ATPase in
      thyroid deficiency since the latter can be reversed by increasing sodium
      reabsorption during continuing hypothyroidism. Furthermore, the modest sodium
      leak of hypothyroid animals does not appear to be due to decreased Na-K-ATPase
      since it was not corrected by uninephrectomy despite restoration of both cortical
      and medullary Na-K-ATPase activity to normal by this maneuver. The close
      correlation between net sodium reabsorption and Na-K-ATPase in all the
      experimental situations described here demonstrates that renal Na-K-ATPase
      changes adaptively in hyper- or hypothyroidism as it does in numerous situations
      in the normal animal, in accord with its postulated role in the active transport
      of sodium across the renal tubule.

PMID- 4348344
TI  - Comparative effects of angiotensin and ACTH on cyclic AMP and steroidogenesis in
      isolated bovine adrenal cells.
AB  - The comparative effects of angiotensin II and adrenocorticotropic hormone (ACTH)
      on cyclic AMP and steroidogenesis were investigated employing isolated bovine
      adrenal cells from the zona fasciculata. Like ACTH, angiotensin produced a prompt
      increase in cyclic AMP which preceded the increase in corticosteroid production.
      Although this increase in cyclic AMP was small when compared to that induced by
      ACTH, it correlated with the amount of steroidogenesis. This observation is
      consistent with the view that cyclic AMP is the intracellular mediator of the
      steroidogenic action of angiotensin. Angiotensin acted synergistically with ACTH
      on cyclic AMP levels. This synergism was not explained by inhibition of
      phosphodiesterase activity. Unlike ACTH, angiotensin failed to stimulate
      adenylate cyclase in broken cell preparations. The observations suggest that more
      than one mechanism may be involved in effects of ACTH and angiotensin on cyclic
      AMP levels.

PMID- 4348345
TI  - Effects of a false neurotransmitter, p-hydroxynorephedrine, on the function of
      adrenergic neurons in hypertensive patients.
AB  - Previous studies have shown that amphetamine and p-hydroxyamphetamine impair
      adrenergic transmission, and it has been suggested that this effect is mediated
      by an active metabolite, p-hydroxynorephedrine (PHN). Studies in experimental
      animals have shown that PHN can deplete and substitute for norepinephrine (NE) in
      the transmitter pool, thus meeting the criteria of a false neurotransmitter. The
      pharmacologic effects of PHN on adrenergic function and NE synthesis were studied
      in eight hypertensive patients and compared with placebo. Mean erect and supine
      blood pressure (BP) decreased 22/14 and 9/6 mm Hg, respectively, during PHN 600
      mg daily. The post-Valsalva diastolic overshoot was abolished. The pressor
      sensitivity to tyramine decreased whereas the pressor response to NE was
      enhanced. A mild natriuresis occurred. The 24 h urinary excretion of
      catecholamines and catecholamine metabolites during the administration of PHN
      compared with placebo changed as follows: vanillylmandelic acid (VMA), 42%
      decrease; NE. 42% decrease; normetanephrine (NM), 400% increase: metanephrine,
      unchanged; dopamine, 40% decrease; while homovanillic acid was unchanged. The sum
      of VMA, NE, and NM decreased 23%. The posttreatment urinary excretion of PHN was
      biexponential with first and second phase half-lives of 13 and 55 h.
      respectively. The time of the second phase closely approximated the recovery of
      the changes in BP and excretion of VMA. No effects of PHN on the central nervous
      system were observed. These studies show that PHN acts peripherally to interfere
      with adrenergic function and NE synthesis in hypertensive patients with a
      resultant decrease in BP.

PMID- 4348347
TI  - Tuberculosis--manifestations at uncommon sites.

PMID- 4348346
TI  - Evidence for stimulation of renal gluconeogenesis by catecholamines.
AB  - Isoproterenol and norepinephrine (10(-4) M) significantly increased cyclic AMP
      formation and glucose production by the isolated tubules of the renal cortex of
      the rat. These effects were abolished by propranolol. Theophylline diminished the
      effects of the catecholamines on gluconeogenesis despite a marked augmentation in
      cyclic AMP concentration. In the absence of calcium ion in the incubation medium,
      isoproterenol stimulates cyclic AMP production, but has no effect on
      gluconeogenesis. It is concluded that catecholamines enhance gluconeogenesis in
      renal cortical tubules by the stimulation of beta adrenergic receptors. This
      effect is probably mediated through adenyl cyclase-cyclic AMP system and requires
      an adequate level of ATP and the presence of calcium ion.

PMID- 4348348
TI  - Intestinal absorption of phosphate in the chick: effect of vitamin D and other
      parameters.

PMID- 4348349
TI  - Influence of dietary protein and carbohydrate levels on liver enzyme activities
      in quail.

PMID- 4348350
TI  - Pre- and post-junctional effects of 1-fluoro-2,4-dinitrobenzene at the frog
      neuromuscular junction.
AB  - 1. FDNB increased by 60-90% the depolarization of the end-plate produced by
      applied carbachol in frog sciatic nerve-sartorius muscle preparations.2. In
      partially curarized preparations, FDNB (0.4 mM) increased the amplitude of the
      end-plate potential by a factor of 1.8.3. The quantal content of end-plate
      potentials was increased by FDNB (2 mM) as determined by the method of
      failures.4. After approximately 25-35 min, neuromuscular transmission was blocked
      by 0.4 mM-FDNB, as evidenced by abolition of neurally elicited end-plate
      potentials. At this stage miniature end-plate potentials could still be recorded,
      which indicates that the neuromuscular block was presynaptic.5. FDNB (0.4 mM)
      increased miniature end-plate potential frequency several hundred-fold when the
      Ringer solution contained normal calcium concentration (1.8 mM) or 0.45 mM
      calcium and 5.4 mM magnesium.6. During the first 60 min of exposure to 0.4 mM
      FDNB there was a slight drop (4-6 mV) in resting potentials of muscle fibres.
      During this period directly initiated action potentials showed a marked decrease
      in the rate of repolarization and a small decrease in the amplitude and rate of
      rise.7. Using the technique of point voltage clamping in tetrodotoxin-treated
      muscles, it has been found that FDNB almost completely abolished the active
      increase in g(K) during stepwise depolarization of the nonjunctional muscle fibre
      membrane from -90 to 0 mV. The passive outward leakage current appeared
      unaffected by FDNB.

PMID- 4348351
TI  - Changes in the statistics of transmitter release during facilitation.
AB  - 1. The statistical nature of transmitter release during facilitation was studied
      at single synaptic sites by recording extracellular excitatory junctional
      potentials from the claw opener muscle in crayfish.2. At low temperatures, single
      quanta could be counted in the responses to nerve impulses. The distribution of
      the number of quanta observed (x) was most accurately described by assuming that
      x is a binomial random variable.3. A quantitative estimate was made of the
      effects of errors in counting quanta due to the simultaneous release of quanta
      and the release of quanta which were not individually detectable above the noise
      of the recording system. Such errors of observation cannot account for the
      deviation of quantal release from a Poisson distribution.4. Facilitated release
      occurred in the responses to the second of two closely following nerve impulses
      and in the responses to successive impulses in a tetanus. In both cases, the
      increase in the average number of quanta released (m) could be attributed
      entirely to an increase in the probability (p) that available quanta were
      released.5. The results can be interpreted most easily in terms of a model in
      which the maximum number of releasable quanta is limited by a finite number of
      discrete release sites within recording distance of the microelectrode. In this
      model, the binomial parameter n is an estimate of the number of these sites, and
      the statistical parameter p is a compound probability depending on the rate of re
      occupying sites after a nerve discharge and the probability that an impulse
      activates an occupied site.

PMID- 4348352
TI  - [Neurology in daily life. 1. Problems of patients with so-called Parinaud's
      syndrome].

PMID- 4348354
TI  - Plasma aldosterone regulation in anephric man.

PMID- 4348353
TI  - [Age difference in the cortisone induced changes of the hepatic cells in mice. 2.
      Ultramicromeasurement and enzymatic cytochemistry by electron microscopy].

PMID- 4348355
TI  - [Do viruses cause tumors in human beings?].

PMID- 4348356
TI  - Influence of lymphography in determining extent of disease in patients with
      lymphoma.

PMID- 4348357
TI  - Crystalloid intracytoplasmic inclusions in lymphocytes of a patient with chronic
      lymphocytic leukemia.

PMID- 4348358
TI  - Effect of Rho on transcription of bacterial operons.

PMID- 4348359
TI  - Human embryonic lung cells abortively infected with Herpes virus hominis type 2
      show some properties of cell transformation.

PMID- 4348360
TI  - Mechanotransduction in insect neurones.

PMID- 4348361
TI  - Skin as aid to neurology.

PMID- 4348362
TI  - Seventeenth Bowditch lecture. Neural and humoral factors in the temporal
      organization of behavior.

PMID- 4348363
TI  - The diagnostic significance of enzyme estimations in clinical medicine.

PMID- 4348364
TI  - Stimulation of splenic prostaglandin release by angiotensin and specific
      inhibition by cysteine 8-AII.

PMID- 4348365
TI  - [Glomus jugular tumors].

PMID- 4348366
TI  - [Is all chronic neurosensory deafness irreversible?].

PMID- 4348367
TI  - Steroids and related products. 38. 11-Aza steroids. 3. The synthesis of 11-aza 9 
      steroids. I.

PMID- 4348368
TI  - An androgen binding protein in the testis cytosol fraction of adult rats.
      Comparison with the androgen binding protein in the epididymis.

PMID- 4348369
TI  - Steroid modifications. II. The effect of ruthenium tetroxide on several aromatic
      steroids.

PMID- 4348370
TI  - [Mechanism of action of the pituitary hormones].

PMID- 4348371
TI  - [Regulation of gonadotropin secretion].

PMID- 4348372
TI  - [The hypothalamo--pituitary--adrenal axis].

PMID- 4348373
TI  - [The role of the pituitary gland in lactation].

PMID- 4348375
TI  - [The role of the pituitary gland in the pathogenesis of Cushing's syndrome].

PMID- 4348374
TI  - [Pituitary function in the fetus].

PMID- 4348376
TI  - Recognition of leprosy.

PMID- 4348377
TI  - [Reversible liver dysfunction in patients with cancer of the kidney].

PMID- 4348378
TI  - Ultrastructure of the pars distalis of the lizard Anolis carolinensis with
      special reference to the identification of the gonadotropic cell.

PMID- 4348379
TI  - The ultrastructure of the accessory sex organs of the male rat. I. Normal
      structure.

PMID- 4348380
TI  - Ultrastructure of the rat neural lobe during recovery from hypertonic saline
      treatment.

PMID- 4348381
TI  - [Giant mitochondria in urinary bladder transitional epithelium of the mole].

PMID- 4348382
TI  - Purification and properties of nucleases from pig pituitary gland.

PMID- 4348383
TI  - Localization of oestradiol receptors in the rat hypothalamus.

PMID- 4348384
TI  - Compartmental arrangement of steroids formed from (1- 14 C)acetate by rat adrenal
      zona glomerulosa and the effect of corticotrophin.

PMID- 4348386
TI  - Early variations of plasma cortisol after pulse intravenous injection of
      dibutyryl cyclic adenosine 3',5'-monophosphate in normal subjects.

PMID- 4348385
TI  - The biosynthesis and secretion of aldosterone by the rat adrenal zona
      glomerulosa, and the significance of the compartmental arrangement of steroids.

PMID- 4348387
TI  - Effects of gonadotrophins and cyclic 3',5'-AMP on in vitro incorporation of ( 3
      H)uridine into RNA of the prepubertal rat ovary.

PMID- 4348388
TI  - Managing the menopause.

PMID- 4348389
TI  - Pathogenicity of low-virulence strains of two canine adenovirus types.

PMID- 4348390
TI  - Chronic superficial keratitis in dogs: negative results of isolation procedures
      for Chlamydia.

PMID- 4348391
TI  - Isolation of parainfluenza type 3 virus from the prepuce of bulls in Northern
      Queensland.

PMID- 4348392
TI  - The influence of age and barbital treatment on the content of cytochrome P-450
      and b 5  and on the activity of glucose-6-phosphatase in microsomes of the rat
      liver and kidney.

PMID- 4348393
TI  - Activation of a specific human plasma kininogenase with trypsin and plasmin.

PMID- 4348395
TI  - Cell-bound antiglial immunity in patients with malignant tumors of the brain.

PMID- 4348394
TI  - Adenosine 3',5'-cyclic monophosphate phosphodiesterase in guinea-pig lung-
      properties and effect of adrenergic drugs.

PMID- 4348396
TI  - Regulatory role of reducing-equivalent transfer from substrate to oxygen in the
      hepatic metabolism of glycerol and sorbitol.

PMID- 4348397
TI  - Differences in nucleotide sequences of ribosomal RNA between the liver and a
      hepatoma of C3H-He mice.

PMID- 4348398
TI  - The effects of thioketo substitution upon uracil-adenine interactions in
      polyribonucleotides. Synthesis and properties of poly (2-thiouridylic acid) and
      poly(2,4-dithiouridylic acid).

PMID- 4348399
TI  - The induction of translocators for di- and tricarboxylic-acid anions in
      Azotobacter vinelandii.

PMID- 4348400
TI  - The role of lysosomal enzymes in skeletal tissues.

PMID- 4348401
TI  - Estimation of virus-neutralizing antibody in microplates.
AB  - A simple and rapid method for the titration of virus-neutralizing antibody is
      described. The micro-apparatus and reagents are readily available from commercial
      sources. Results are included from selected cases which illustrate various
      conditions of immune status and response.

PMID- 4348403
TI  - Frequency of intraendothelial 'virus-like' particles: an electron microscopy
      study of 376 human renal biopsies.
AB  - Intraendothelial ;virus-like' particles were found in all cases requiring a renal
      biopsy: in 89% of patients with systemic lupus erythematosus (SLE), in 73% of
      those receiving renal transplants more than one year before, and in 24.5% of all
      other renal biopsies.

PMID- 4348402
TI  - FL 1060: a new beta-lactam antibiotic with novel properties.
AB  - The effect of FL 1060, a newly described beta-lactam antibiotic, on three strains
      of Escherichia coli was studied. The agent showed extraordinarily high activity
      as judged by conventional titrations, but inoculum size, osmolality of the
      medium, and length of the incubation period were all found to have a marked
      effect on the result. Continuous turbidimetric monitoring and microscopical
      observation of cultures of E. coli exposed to FL 1060 showed the effect of the
      antibiotic to have many novel features. Exposed bacterial rods converted to
      spherical forms, but in a different manner from that of classical penicillin
      mediated transformation. Furthermore, although FL 1060 was bactericidal for the
      majority of the bacterial population, a fraction not only survived its lethal
      action but grew in high concentrations of the agent thereby producing a
      phenotypically resistant population which nonetheless continued to show
      characteristic morphological deformities. Possible reasons for this anomalous
      behaviour are discussed.

PMID- 4348404
TI  - Serial nitroblue tetrazolium tests in the management of infection.
AB  - Two cases are described in which extensive use was made of the nitroblue
      tetrazolium (NBT) test. In the first case the advantages of using this technique
      to diagnose and control infection is shown; in the second the considerable
      advantage of the speed of the technique. In both of these cases the test made a
      material contribution to the management of the patient, and it is concluded that
      the test brings bacteriological control of the patient within the immediate
      clinical area, thus overcoming one of the principal disadvantages of the
      classical bacteriological methods.

PMID- 4348405
TI  - Cardiac mitochondrial activity in acute and chronic cyanosis.

PMID- 4348407
TI  - [Nursing of a patient requiring special care following discharge from the
      hospital].

PMID- 4348406
TI  - Relationship of cyclic AMP to secretin stimulation of the pancreas.

PMID- 4348408
TI  - Fatal measles infection in children with leukemia.

PMID- 4348409
TI  - Effects of 3',5'-cyclic nucleotides on adrenocortical cells of hypophysectomized
      rats. A stereologic and autoradiographic study.

PMID- 4348410
TI  - Arsenic intoxication from well water in the United States.

PMID- 4348411
TI  - Adrenocortical response to ACTH in Addison's disease.

PMID- 4348412
TI  - Neuropathy of long-distance running.

PMID- 4348413
TI  - Intranuclear inclusion bodies.

PMID- 4348414
TI  - The amino-acid sequence of cytochrome c from Euglena gracilis.

PMID- 4348416
TI  - A preliminary investigation of the swine vesicular disease epidemic in Britain.

PMID- 4348415
TI  - The properties and amino-acid sequence of cytochrome c from Euglena gracilis.

PMID- 4348417
TI  - Electron microscopic study of liver lesions, especially hepatic megalocytosis
      induced by 1-(4-dimethylamino-benzylidene)-indene (DABI) in mice.

PMID- 4348418
TI  - [Neuropsychologic analysis and differentiation of amnesia syndromes].

PMID- 4348419
TI  - [Quadridistal amyotrophic neuropathy caused by hyperinsulinism: improvement after
      excision of a langerhansian pancreatic adenoma].

PMID- 4348420
TI  - The role of reticular formation in integration.

PMID- 4348421
TI  - Studies on the tardigrades. 3. Fine structure of the esophagus of Milnesium
      tardigradum Doyere.

PMID- 4348422
TI  - The digital pads of the tree frog, Hyla cinerea. I. The epidermis.

PMID- 4348423
TI  - Treatment of amoebic liver abscess and amoebic dysentery with metronidazole.

PMID- 4348424
TI  - Australia antigen in liver disease in Zambia.

PMID- 4348425
TI  - [Detection of viral antigens in bone marrow cells].

PMID- 4348426
TI  - [Interference phenomenon in detection of the avian bronchitis virus].

PMID- 4348427
TI  - [Camel pox caused by pox vaccine (detritus)].

PMID- 4348428
TI  - Sterol and phospholipid biosynthesis in phytohemagglutinin stimulated human
      lymphocytes.

PMID- 4348429
TI  - A new method for measuring ultrasonic velocity.

PMID- 4348430
TI  - Pseudomonas cytochrome c peroxidase. V. Absorption spectra of the enzyme and of
      its compounds with ligands. Inhibition of the enzyme by cyanide and azide.

PMID- 4348431
TI  - Recurring digital fibrous tumour of childhood. Case report and survey.

PMID- 4348432
TI  - [Pectoral aplasia and dysdactylia syndrome (Poland). Apropos of 2 cases].

PMID- 4348433
TI  - [Brachysyndactylia with agenesis of the pectoralis major].

PMID- 4348434
TI  - Fine structure of human pituitary adenoma.

PMID- 4348435
TI  - Encephalomyocarditis virus (E variant) in mice. Pancreatic changes.

PMID- 4348436
TI  - Nuclear DNA in salivary gland tumors. II. Adenocystic carcinomas.

PMID- 4348438
TI  - Delayed cutaneous metastases of mucus-producing cell carcinoma of the stomach.

PMID- 4348437
TI  - Treatment of vaginal trichomoniasis with a new anti-protozoal compound ( 
      chloromethyl-2-methyl-5-nitro-1-imidazole-ethanol).

PMID- 4348440
TI  - Conformational studies on lipoamide dehydrogenase from pig heart. 2.
      Spectroscopic studies on the apoenzyme and the monomeric and dimeric forms.

PMID- 4348439
TI  - Conformational studies on lipoamide dehydrogenase from pig heart. I.
      Interconversion of dissociable and non-dissociable forms.

PMID- 4348441
TI  - Conformational studies on lipoamide dehydrogenase from pig heart. 3. The binding
      of sodium dodecylsulphate.

PMID- 4348442
TI  - Conformational studies on lipoamide dehydrogenase from pig heart. 4. The binding
      of NAD +  to non-equivalent sites.

PMID- 4348443
TI  - The initiation of protein synthesis directed by the RNA from encephalomyocarditis
      virus.

PMID- 4348444
TI  - Slow conformational changes of the inorganic pyrophosphatase from bakers' yeast
      induced by divalent metal ions.

PMID- 4348445
TI  - Binding of ligands to the inorganic pyrophosphatase of bakers' yeast.

PMID- 4348446
TI  - Suppression of testicular androgen synthesis in the rat by ethylene
      dimethanesulphonate.

PMID- 4348447
TI  - Antagonists of trophic hormones.

PMID- 4348448
TI  - Temperature studies of the hand and its claw deformities due to peripheral nerve
      paralysis in leprosy.

PMID- 4348449
TI  - Sarcoma of tendon sheath.

PMID- 4348450
TI  - Influence of time factor on the restoration of adrenal weight and cortical
      functions in hypophysectomized rats.

PMID- 4348451
TI  - Lipolytic enzymes and the action of ACTH on lipid metabolism in rat adrenals.

PMID- 4348452
TI  - Viral-host relationships in chronic diseases of man.

PMID- 4348453
TI  - On the aetiology of whooping cough.
AB  - The results of routine bacterial and viral studies on 483 patients with whooping
      cough, investigated at one hospital over a five year period are presented. The
      possible role of respiratory viruses in the aetiology of the disease is
      discussed.

PMID- 4348454
TI  - Social class and infectious mononucleosis.
AB  - The socio-economic status of 80 patients with infectious mononucleosis was
      compared with the socio-economic distribution of the general population in the
      same area of south-west London. An excess incidence of infectious mononucleosis
      was observed among subjects from upper socio-economic groups. A possible
      relationship between this observation and the epidemiology of the Epstein-Barr
      virus is discussed.

PMID- 4348455
TI  - Epstein-Barr virus antibody in cases and contacts of infectious mononucleosis; a
      family study.
AB  - Serological investigations were carried out on 147 patients with Paul-Bunnell
      positive infectious mononucleosis (IM) from the general population. All possessed
      antibody to the Epstein-Barr virus (EBV) and 63% showed serological evidence of
      recent infection. Contacts of 132 patients, 306 in all, were followed
      serologically; within 6 months of the index cases' illness twenty one contacts
      developed evidence of EBV infection or re-infection and of these five developed
      overt IM. The secondary attack rate of EBV infection among susceptible contacts
      was at least 19%; the corresponding figure for clinically apparent IM was 6%. EBV
      antibody prevalence among patients' siblings was significantly lower than among
      age-matched controls, suggesting that cases of IM come from families with a lower
      than normal previous experience of the virus. Of thirteen patients with
      persistently Paul-Bunnell negative ;glandular fever' four had serological
      evidence of recent EBV infection and two had probable cytomegalovirus
      mononucleosis. Recent EBV infection may have been associated with the illnesses
      of five of the remaining patients.

PMID- 4348456
TI  - Pertussis antibodies in the sera of children exposed to Bordetella pertussis by
      vaccination or infection.
AB  - Low agglutinin titres to pertussis suspensions were found in 99% of sera from a
      group comprising healthy adults and non-vaccinated, non-infected infants of 1-6
      months of age. These are attributable to agglutinins to heat-stable antigens
      and/or heat labile agglutinogen 1, and cross-absorption tests must be done on the
      sera in order to distinguish between the two. Agglutinins to agglutinogens 2 and
      3 were found in only about 20% of adult sera. Bactericidal antibody was low in
      titre or absent in all sera from non-exposed individuals.Raised bactericidal
      antibody titres and the presence of agglutinins 2 and 3 were attributed to
      exposure to Bordetella pertussis antigens, either as vaccine or as infection. The
      variation, amongst both vaccinated and infected children, was very great. A
      vaccinated child who became ill responded to the infection in much the same way
      as a non-vaccinated child. We were unable to relate the immunity of the child to
      the titres either of agglutinins or of the bactericidal antibody.The protective
      ability of sera from vaccinated or infected children measured in mice against
      small, lethal brain infections was also unrelated to the state of immunity in the
      children, but this protective ability was correlated with the complement-mediated
      bactericidal antibody titres of the sera.The distribution of agglutinins,
      bactericidal antibody, and anti-haemagglutinin in serum IgG and IgM was different
      in vaccinated and infected children.

PMID- 4348457
TI  - An analog computer study of fast, isolated movements.

PMID- 4348458
TI  - Homology between Epstein-Barr virus DNA and viral DNA from Burkitt's lymphoma and
      nasopharyngeal carcinoma determined by DNA-DNA reassociation kinetics.

PMID- 4348460
TI  - Effect of magnesium on horizontal cell activity in the skate retina.

PMID- 4348459
TI  - Cell fusion induced by a virus within the zona pellucida of mouse eggs.

PMID- 4348461
TI  - Differentiation between necrotic ulcerative gingivitis and primary herpetic
      gingivostomatitis.

PMID- 4348462
TI  - [Mechanism of action of a bronchodilator agent. (Comprehensive review)].

PMID- 4348463
TI  - 1 -Hydroxy derivative of vitamin D 3 : a highly potent analog of 1 ,25
      dihydroxyvitamin D 3 .
AB  - The 1alpha-hydroxy derivative of vitamin D(3) has been chemically synthesized and
      tested for its biological activity. This analog has comparable biological
      activity on a weight basis to 1,25-dihydroxyvitamin D(3) in the stimulation of
      intestinal calcium transport and bone calcium mobilization in normnal and
      anephric rats. Because the 1alpha-hydroxy derivative is synthesized from
      cholesterol, it is easier and less expensive to prepare than 1alpha,25-dihydroxy
      derivative, making it attractive as a drug in the treatment of renal
      osteodystrophy and hypopara-thyroidism.

PMID- 4348464
TI  - Natural abundance carbon-13 nuclear magnetic resonance spectra of human serum
      lipoproteins.
AB  - Human serum lipoproteins have been studied by Fourier transform nuclear magnetic
      resonance of carbon-13 in natural abundance. Spectra of highdensity, low-density,
      and very-low-density lipoproteins were recorded and partly assigned. The
      prominent features of these spectra reflect the qualitative and quantitative
      composition of the lipid moiety of these complexes. The results suggest that
      carbon-13 nuclear magnetic resonance will be a useful technique for studies of
      the structural and dynamic parameters of lipoproteins.

PMID- 4348465
TI  - [Ultrasonic diagnosis in obstetrics and perinatology].

PMID- 4348466
TI  - Extraction of equine infectious anemia immunodiffusion antigen with the aid of
      the chaotropic agent, thiocyanate.
AB  - Immunodiffusion antigen from spleens of horses infected with equine infectious
      anemia virus was prepared by methods employing freeze-thaw cycles and thiocyanate
      treatment. Thiocyanate (0.5 M) permitted the recovery of the greatest amount of
      antigen. Furthermore, it was most effective for recovery of immunodiffusion
      antigen from spleens which yielded unsatisfactory concentrations of antigen by
      the conventional freeze-thaw or water-extraction methods. The reactivity of the
      antigen did not appear to be affected by this chemical treatment.

PMID- 4348467
TI  - Virus susceptibility of a new simian cell line of fetal origin.
AB  - The cultivation and characterization of a cell line derived from the foreskin of
      a fetal, rhesus monkey (rhfs2) are described. This cell line has proven
      satisfactory for isolation and assay of a variety of viral agents of human and
      simian origin. Virus titrations performed on foreskin cells yielded titers
      comparable to, or higher than, those obtained in rhesus monkey kidney cells (LLC
      MK2). Replicate isolation attempts in our laboratory from simian clinical
      specimens have proven rhfs2 superior to LLC-MK2 for ease of detection and
      frequency of isolation.

PMID- 4348468
TI  - Rapid method to determine labeling specificity of radioactive enteroviruses.
AB  - The specificity of labeling enteroviruses with (32)P-labeled NaH(2)PO(4) or (14)C
      leucine can be determined by comparing the percent adsorption of infective
      particles and radioactivity to membrane (Millipore) filters.

PMID- 4348469
TI  - Evaluation of two types of infectious mononucleosis antigen slides by the
      indirect fluorescent-antibody technique.
AB  - The efficiency of two types of antigen slides was compared by using the indirect
      fluorescent-antibody technique. Fifty sera from infectious mononucleosis patients
      were tested concurrently on the two sets of slides for antibody to Epstein-Barr
      virus. The indirect fluorescent-antibody serum titer readings from the epoxy
      slides were either equal to or twofold higher than those from the cover slip
      slides.

PMID- 4348470
TI  - Neuraminidase induced loss in the transplantability of murine leukaemia L 1210,
      induction of immunoprotection and the transfer of induced immunity to normal DBA
      2 mice by serum and peritoneal cells.
AB  - Leukaemia L 1210 cells preincubated in vitro with neuraminidase preparations
      derived either from Vibrio cholerae (VCN) or Clostridium perfringens (CPN) lost
      their i.p. transplantability for normal DBA/2 mice. This loss of
      transplantability could not be observed when the enzyme treated cells were
      implanted in mice whose immune status was suppressed by prior cyclophosphamide
      treatment. Mice receiving i.p. implants of enzyme treated leukaemia cells
      developed immunity to subsequent i.p. challenge with untreated L 1210 cells but
      not to a challenge with Ehrlich ascites tumour cells. The magnitude of immune
      response evoked by L 1210 cells preincubated with 250 u/ml of VCN or 35 MUg/ml of
      CPN for 60 minutes was of relatively low level when compared with the immunity
      induced by leukaemia cells preincubated with 50 u/ml of VCN or 15 MUg/ml of CPN
      for 30 or 60 minutes. Evidence is presented to show that the induced immunity can
      be transferred passively with the serum and with the peritoneal cells from the
      mice implanted with VCN treated L 1210 cells to normal DBA/2 mice. The
      significance of the neuraminidase induced increase in the immunogenicity of
      treated tumour cells is discussed.

PMID- 4348471
TI  - Human peripheral lung tumours: light and electron microscopic correlation.
AB  - Thirteen human peripheral lung tumours have been studied in both light and
      electron microscopy. They were classified as epidermoid carcinoma, mucus
      secreting cell adenocarcinoma, and alveolar cell adenocarcinoma, the latter made
      up of granular pneumocytes. Alveolar cell cancer, as defined by ultrastructural
      features, could assume different gross histological patterns in light microscopy,
      and therefore electron microscopy is required for its identification.Since
      neither squamous nor mucous metaplasia was observed in any alveolar cell tumour,
      it is tentatively suggested that all peripheral lung tumours which lack these
      features may be derived from granular pneumocytes, irrespective of whether they
      appear to be adenocarcinomata or large cell carcinomata when examined by light
      microscopy.

PMID- 4348473
TI  - Glomus tumours.

PMID- 4348474
TI  - Early diagnosis of nephroblastoma.

PMID- 4348472
TI  - Glioblastoma multiforme: a controlled trial to assess the value of specific
      active immunotherapy in patients treated by radical surgery and radiotherapy.
AB  - The results are reported of a randomized prospective clinical trial carried out
      to assess the value of specific active immunotherapy using irradiated autologous
      tumour cells in patients with glioblastoma multiforme treated by radical surgery
      and post-operative irradiation. The results in 62 patients show no statistically
      significant difference in survival between the group receiving adjuvant
      autologous tumour cells and those treated with surgery and radiotherapy alone.
      All 27 patients receiving tumour cells were dead at 30 months, whereas 7 of the
      35 controls were alive at this time. The results were considered sufficiently
      discouraging to abandon the trial at this stage on the grounds that there was
      sufficient evidence in this study that the administration of irradiated
      autologous cells was of no benefit to patients with high grade astrocytomata.

PMID- 4348475
TI  - Comparative trial of P1496, a new non-steroidal oestrogen analogue.
AB  - The results are reported of a preliminary trial of P1496, a new non-steroidal
      oestrogen analogue, compared with a conjugated equine oestrogen and a placebo.
      The oestrogenicity of both substances was well substantiated by vaginal
      epithelial maturation indices. P1496 was superior to conjugated equine oestrogen
      in producing a significant reduction of plasma calcium levels and a possible
      reduction in serum cholesterol. Conjugated oestrogen caused slightly more nausea
      than P1496 but there were no notable side effects from either drug. P1496 is
      considered to be at least as effective an oestrogenic substance as conjugated
      oestrogen and worthy of further therapeutic evaluation.

PMID- 4348476
TI  - Persistent haemagglutination for infectious mononucleosis in rheumatoid
      arthritis.

PMID- 4348477
TI  - Infection with E.B. virus.

PMID- 4348478
TI  - Recovery of adrenal function after substitution of beclomethasone dipropionate
      for oral corticosteroids.
AB  - Of 16 steroid-dependent asthmatic patients oral treatment has been discontinued
      in six and reduced in four after the introduction of beclomethasone dipropionate.
      Substitution of inhaled beclomethasone for oral steroids was unsuccessful in the
      remaining six patients. Serial adrenal function studies in the patients whose
      oral treatment was discontinued showed progressive recovery, and five out of six
      had a normal response to tetracosactrin stimulation after two months.

PMID- 4348479
TI  - Glomus tumours.

PMID- 4348480
TI  - Herpes simplex and zoster.

PMID- 4348481
TI  - [10-year survival after nephrectomy for rupture of Wilms' tumor].

PMID- 4348482
TI  - [Selective bronchial arteriography in bronchogenic carcinomas].

PMID- 4348483
TI  - Determination of IgG heavy chains by electroimmunodiffusion in the nanogram
      range: simultaneous application to serum and CSF of neurological patients.

PMID- 4348484
TI  - Plasma lipids in patients with chronic renal failure.

PMID- 4348485
TI  - The diagnostic value of thrombocytic glucose-6-phosphatase in patients with von
      Gierke's disease and its heterozygotes.

PMID- 4348486
TI  - [Sex-specific differences of serum proteins in adults and influence of oral
      hormonal contraceptives on serum protein composition].

PMID- 4348487
TI  - Histochemical and histological studies of rat myocardium following mechanical
      compression.

PMID- 4348488
TI  - Crystalloid inclusions in mitochondria of renal tubules.

PMID- 4348490
TI  - Growth and its regulation in the healthy child.

PMID- 4348489
TI  - [Development of enzyme pattern in the ependyma of the 3rd ventricle in the chick
      embryo].

PMID- 4348491
TI  - Electron spin resonance of spin labels in organic inclusion crystals. Models for
      anisotropic motion in biological membranes.

PMID- 4348492
TI  - A theoretical model for the effects of local nonpolar heme environments on the
      redox potentials in cytochromes.

PMID- 4348493
TI  - A convenient synthesis of 1 -hydroxy-vitamin D 3 .

PMID- 4348495
TI  - Different patterns of neurologic involvement with herpes simplex virus types 1
      and 2: isolation of herpes simplex virus type 2 from the buffy coat of two adults
      with meningitis.

PMID- 4348494
TI  - Hindlimb muscle fiber populations of five mammals.

PMID- 4348496
TI  - The limited effect of nasal interferon induced by rhinovirus and a topical
      chemical inducer on the course of infection.

PMID- 4348497
TI  - Inhibition of oral shedding of herpes simplex virus by cytosine arabinoside.

PMID- 4348498
TI  - Impaired production of interferon in lymphocytes from immunosuppressed patients.

PMID- 4348499
TI  - Leukocyte-transforming agent: prolonged excretion by patients with mononucleosis
      and excretion by normal individuals.

PMID- 4348500
TI  - Adenoid cystic carcinoma of the ear canal.

PMID- 4348502
TI  - Survey for antibodies to canine viruses in selected wild mammals.

PMID- 4348501
TI  - Lipid metabolism in pregnancy. I. Changes in lipoprotein triglyceride and
      cholesterol in normal pregnancy and the effects of diabetes mellitus.

PMID- 4348503
TI  - Ultrasonic visualization in determination of tumor growth rate.

PMID- 4348504
TI  - [Radical surgery in tumors of the thoracic trachea].

PMID- 4348505
TI  - Prism adaptation and brain damage.

PMID- 4348506
TI  - [Collagen peptidase as a measure of collagen turnover in sarcoidosis].

PMID- 4348507
TI  - [Results of radiotherapy of brain tumors (1960-1970)].

PMID- 4348508
TI  - Indium-113 m generator using alumina or silica gel.

PMID- 4348509
TI  - RNA-directed DNA synthesis and RNA tumor viruses.

PMID- 4348510
TI  - Virus-erythrocyte interactions.

PMID- 4348511
TI  - Characteristics of tumors induced in mammals, especially rodents, by viruses of
      the avian leukosis sarcoma group.

PMID- 4348512
TI  - Oxygenated cytochrome P-450 as an intermediate in hydroxylation reactions.

PMID- 4348513
TI  - [Biological properties of Clostridium, isolated from food products during
      preservation].

PMID- 4348514
TI  - Association between malignant disease in children and maternal virus infections.
AB  - The possibility of an association between virus infections during pregnancy and
      subsequent malignant disease in the child has been investigated using
      retrospective data from the Oxford Survey of Childhood Cancers. Such an
      association appears to exist for influenza, chickenpox, and possibly rubella. For
      influenza and rubella the estimated risk is small; the data do not permit an
      estimate to be made directly in the case of chickenpox. It is suggested that
      there may be a specific association between maternal chickenpox and tumours of
      the nervous system.It is important to emphasize that, even if the relative risk
      associated with these viruses is fairly large, the number of cases of childhood
      cancer and leukaemia actually attributable to them is probably very small.

PMID- 4348516
TI  - Proteolytic activity of Entamoeba histolytica. 3. Some properties of the enzyme.

PMID- 4348515
TI  - Dipyrone in bronchial asthma.

PMID- 4348517
TI  - [Action mechanism of androgen on the prostate].

PMID- 4348518
TI  - [Long term treatment of multiple myeloma].

PMID- 4348519
TI  - Antipsychotic drug actions: a clue to the neuropathology of schizophrenia?

PMID- 4348520
TI  - [The technique of pancreato-cholangiography (PCG)].

PMID- 4348521
TI  - [The diagnostic value of pantomosialography].

PMID- 4348522
TI  - [Transfemoral arteriography for diseases in childhood. Report of 1174 cases from
      the literature and 68 personal cases].

PMID- 4348523
TI  - [New radiological-surgical concepts in the primary treatment of malignant
      melanomas].

PMID- 4348524
TI  - [The value of lymphography for malignant processes above the diaphragm].

PMID- 4348525
TI  - [Two examples of gas emboli in the portal vein system due to gastric volvulus].

PMID- 4348526
TI  - [Roentgenologic follow-up studies of the remaining rectal space following sacro
      abdominal rectum extirpation].

PMID- 4348527
TI  - [Value of combination liver scintigraphy and needle aspiration biopsy in liver
      metastases].

PMID- 4348528
TI  - [The value of the isotope nephrogram for study of compensatory hyperplasia of the
      remaining kidney following nephrectomy].

PMID- 4348529
TI  - [113m-indium-albumin micro-spheres for perfusion scintigraphy of the lungs].

PMID- 4348530
TI  - [Rare benign cystic changes in the female breast].

PMID- 4348531
TI  - [Arteriographic findings in a cystic osteoid sarcoma of the breast].

PMID- 4348532
TI  - [Angiographic findings in synovial sarcoma].

PMID- 4348533
TI  - [Angiographic demonstration of an excessive thoracic-abdominal aortic aneurysm].

PMID- 4348535
TI  - [Missing major pectoral muscle].

PMID- 4348534
TI  - [Abnormal opening of right hypogastric vein].

PMID- 4348536
TI  - [Phytobezoar of the stomach (case report0].

PMID- 4348537
TI  - [Double anterior atlas arch].

PMID- 4348538
TI  - [Defect of lambda suture: typical change in Recklinghausen's neurofibromatosis].

PMID- 4348539
TI  - [Herbert Junghanns' 70th birthday].

PMID- 4348540
TI  - A proton magnetic resonance study of the conformations of 3',5'-cyclic
      nucleotides.

PMID- 4348541
TI  - A  13 C and  1 H nuclear magnetic resonance study of the conformations of 2',3'
      cyclic nucleotides.

PMID- 4348542
TI  - Enzymatic preparation of an optically active phosphotriester, asymmetric only at
      phosphorus.

PMID- 4348543
TI  - The effect of cycloheximide on the interaction between mitochondrial respiration
      and gluconeogenesis in guinea pig and rat liver.

PMID- 4348545
TI  - A class I (Schiff base) fructose diphosphate aldolase of prokaryotic origin.
      Purification and properties of Micrococcus aerogenes aldolase.

PMID- 4348544
TI  - The regulation of nicotinamide adenine dinucleotide-linked substrate oxidation in
      isolated liver mitochondria.

PMID- 4348546
TI  - Structural comparisons between the class I fructose diphosphate aldolases from
      Micrococcus aerogenes and rabbit.

PMID- 4348547
TI  - Enzymatic epoxidation. II. Comparison between the epoxidation and hydroxylation
      reactions catalyzed by the  -hydroxylation system of Pseudomonas oleovorans.

PMID- 4348548
TI  - Formation of monoenoic fatty acids by desaturation in rat brain homogenate. Some
      properties of the enzyme system of 10-day-old brain.

PMID- 4348549
TI  - Purification and properties of the colicin E3 receptor of Escherichia coli.

PMID- 4348550
TI  - Regulation of adenosine 3',5'-monophosphate-dependent protein kinase. I.
      Preliminary characterization of the adipose tissue enzyme in crude extracts.

PMID- 4348552
TI  - Squalene synthetase. II. Purification and properties of bakers' yeast enzyme.

PMID- 4348551
TI  - Regulation of adenosine 3',5'-monophosphate-dependent protein kinase. II.
      Hormonal regulation of the adipose tissue enzyme.

PMID- 4348553
TI  - Squalene synthetase. 3. Mechanism of the reaction.

PMID- 4348554
TI  - Conditionally lethal mutations in Chinese hamster cells. I. Isolation of a
      temperature-sensitive line and its investigation by cell cycle studies.

PMID- 4348555
TI  - Investigations of the mechanism of decreased tumorigenicity of cells grown in
      BrdU.

PMID- 4348556
TI  - The ability of calcium to change cyclic AMP from a stimulator to an inhibitor to
      thymic lymphoblast proliferation.

PMID- 4348557
TI  - Differential blood lipid pattern in diabetics and atherosclerotics.

PMID- 4348558
TI  - Viruses causing common respiratory infections in man.

PMID- 4348559
TI  - Endocrine causes of hypertension.

PMID- 4348560
TI  - Ultrastructural cytopathology of mouse myocardium associated with EMC viral
      infection.

PMID- 4348562
TI  - Patient participation in ward program planning.

PMID- 4348563
TI  - Aspects of the Petrie test in psychiatric patients.

PMID- 4348561
TI  - Adenylate kinase in human tissue. II. Serum adenylate kinase and myocardial
      infarction.

PMID- 4348564
TI  - The institutional milieu as a work environment.

PMID- 4348565
TI  - Conjoint therapy as an adjunct to individual therapy.

PMID- 4348566
TI  - Automated nursing notes in a psychiatric institution.

PMID- 4348567
TI  - Phobia: a private experience.

PMID- 4348568
TI  - Constraints and opportunities in a nursing career.

PMID- 4348570
TI  - Medicare--nursing home benefits.

PMID- 4348569
TI  - An old fashioned method to deal with delinquent behavior: more effective than
      courts?

PMID- 4348571
TI  - Nurses' attitude toward heroin addicts.

PMID- 4348572
TI  - Identification of laboratory animals: freeze marking.

PMID- 4348573
TI  - Immunologic renal disease in laboratory animals.

PMID- 4348574
TI  - [Paradoxical sleep and memory. Polygraphic study of night sleep and of oniric
      activity in Korsakoff's syndrome].

PMID- 4348575
TI  - The plasmid of Salmonella typhimurium LT2.

PMID- 4348576
TI  - Catecholamine and Ca 2+  activation of adenylate cyclase systems in synaptosomal
      fractions from rat cerebral cortex.

PMID- 4348577
TI  - [Histamine and the stomach secretion in the rat. Adenosine-3',5'-monophosphate as
      "second messenger"].

PMID- 4348578
TI  - A patient with multiple insulinomata.

PMID- 4348579
TI  - Thymidine kinase activity in Burkitt lymphoblastoid somatic cell hybrids after
      induction of the EB virus.

PMID- 4348580
TI  - Syncytial giant cell focus assay for viruses derived from feline leukemia and a
      simian sarcoma.

PMID- 4348581
TI  - Effect of zinc on the viability and phagocytic capacity of peritoneal
      macrophages.

PMID- 4348582
TI  - Study on plasma cyclic nucleotide concentrations in fasting rats.

PMID- 4348583
TI  - The effects of an acid pH upon the induction of antiviral resistance in vitro by
      interferon.

PMID- 4348584
TI  - Virus resistance in rabbit kidney cell cultures contaminated by a protozoan
      resembling Encephalitozoon cuniculi.

PMID- 4348585
TI  - Regulation of myocardial prostaglandin dehydrogenase activity. The role of cyclic
      3',5'-AMP and calcium ions.

PMID- 4348586
TI  - Charge heterogeneity of human low density lipoprotein (LDL).

PMID- 4348587
TI  - [Study of the sinus network in lymphographic diagnosis of malignant lymph nodes].

PMID- 4348588
TI  - Effect of angiotensin II on plasma free fatty acids in hypertensive subjects with
      and without overweight.

PMID- 4348589
TI  - Luxation and ligamentous injuries of the elbow of the dog.

PMID- 4348590
TI  - [The functional state of the adrenal cortex in lymphogranulomatosis patients].

PMID- 4348591
TI  - [Tissue respiration in liver mitochondria of rats with tumors].

PMID- 4348592
TI  - [The influence of mecytosine on the antiblastic effect of radiation].

PMID- 4348593
TI  - [Unusual spread of primary liver cancer (1 case)].

PMID- 4348594
TI  - [The electron paramagnetic resonance spectrum of blastomogenic metabolites of
      tryptophan and tyrosine].

PMID- 4348595
TI  - [Molecular basis of the relation between the cytotoxic effect of antineoplastic
      compounds and the cell cycle phase].

PMID- 4348596
TI  - [Use of optical quantum generators (lasers) in oncology].

PMID- 4348597
TI  - Vitamin D. Metabolism and mechanism of action.

PMID- 4348598
TI  - Immunity and immunopathology in virus infections.

PMID- 4348600
TI  - Double drug-dependence in a poliovirus strain.

PMID- 4348599
TI  - On the prevention of virus induced blockade of cell protein synthesis by specific
      inhibitors of poliovirus growth.

PMID- 4348601
TI  - Effect of chlorophenoxyisobutyric acid (CPIB) on fat-mobilizing lipolysis and
      cyclic AMP levels in rat epididymal fat.

PMID- 4348603
TI  - [Diffusion of  45 Ca,  85 Sr, and  32 P in hydroxyapatite].

PMID- 4348602
TI  - A case of massive hypertriglyceridemia corrected by nicotinic acid or
      nicotinamide therapy.

PMID- 4348604
TI  - Electromagnetic measurement of iliac artery blood flow in the rat: on-line
      integration of flow.

PMID- 4348605
TI  - [Pseudohyperparathyroidism as a paraneoplastic syndrome in a care of carcinoma of
      the stomach].

PMID- 4348606
TI  - Multiple sclerosis: an immunologic reassessment.

PMID- 4348607
TI  - Chemical stimulation of the brain: relationship between neural activity and water
      ingestion in the rat.

PMID- 4348608
TI  - Mapping and characerization of mutants of Pseudomonas aeruginosa affected in
      nitrate respiration in aerobic or anaerobic growth.

PMID- 4348609
TI  - Localized muscle fatigue--definiton and measurement.

PMID- 4348610
TI  - Metastatic carcinomas involving the testis: a review.

PMID- 4348611
TI  - Serological survey of rhinovirus infections in Japan.

PMID- 4348612
TI  - Antagonism of non-inducer ribonucleic acid against induction of antiviral cell
      resistance and interferon by inducer ribonucleic acid.

PMID- 4348613
TI  - Isolation and immunological characterization of human glomerular basement
      membrane antigens.

PMID- 4348614
TI  - The effect of a reversed cycle of sleep and wakefulness on diurnal EEG patterns
      in rhesus monkeys.

PMID- 4348615
TI  - Damage to microsomal membrane by lipid peroxidation.

PMID- 4348616
TI  - Carcino-foetal human liver ferritins.

PMID- 4348617
TI  - The use of phospholipid film for shaping cell cultures.

PMID- 4348618
TI  - Comparison of ribosomal protein synthesis in Becker and Duchenne muscular
      dystrophies.

PMID- 4348619
TI  - Cerebral dysautoregulation in central neurogenic orthostatic hypotension (Shy
      Drager syndrome).

PMID- 4348620
TI  - On thalamic substrates of cortical synchrony.

PMID- 4348621
TI  - [Case of adenocarcinoma in uterine adenomyosis. Role of gynecography (GC) in
      detecting unpalpable lesions in myometrium].

PMID- 4348622
TI  - The REM sleep-inducing action of a naturally occurring organic bromine compound
      in the encephale isole cat.

PMID- 4348623
TI  - Electron spin resonance studies of  -irradiated dinucleotides and related
      compounds at 77 degrees K.

PMID- 4348624
TI  - Hepatic tumours in infancy and childhood.

PMID- 4348625
TI  - Neurophysiological studies on muscle function in the stump of above-knee
      amputees.

PMID- 4348626
TI  - [X-ray diagnosis of esophageal stenosis of inflammatory origin].

PMID- 4348627
TI  - [Ultrastructure of mixed mammary gland tumours in bitches. I. The incidence of
      myoepithelial cells in myxoid areas].

PMID- 4348632
TI  - Multiple virus isolations from a pregnant patient.

PMID- 4348633
TI  - [Invagination in adults and its problems].

PMID- 4348634
TI  - [Respiratory function during physiological sleep].

PMID- 4348635
TI  - Polygraphic aspects of sleep in man.

PMID- 4348636
TI  - Apnoeic periods and the respiratory related arousal patterns during sleep in the
      Pickwickian syndrome. A polygraphic study.

PMID- 4348637
TI  - Hypersomnia with periodic breathing: periodic apneas and alveolar hypoventilation
      during sleep.

PMID- 4348638
TI  - Insomnia, narcolepsy, and sleep apneas.

PMID- 4348639
TI  - Continuous recording of the pulmonary and systemic arterial pressure during sleep
      in syndromes of hypersomnia with periodic breathing.

PMID- 4348640
TI  - Tracheostomy in hypersomnia with periodic breathing.

PMID- 4348641
TI  - Hydrochlorothiazide therapy in nephrolithiasis. Effect on the urinary activity
      product and formation product of brushite.

PMID- 4348642
TI  - Principles of automatic analysis of sleep records with a hybrid system.

PMID- 4348643
TI  - Hereditary neuronal abiotrophy in the Swedish Lapland dog.

PMID- 4348644
TI  - [Action mechanism of steroid hormones].

PMID- 4348645
TI  - Multiple effects of glucocorticoids on TSH secretion in unanesthetized rats.

PMID- 4348646
TI  - Stimulation of the adenyl cyclase-cyclic AMP system in the thyroid of the rat.

PMID- 4348647
TI  - Corticosteroid feedback control of ACTH secretion: effect of stress-induced
      corticosterone ssecretion on subsequent stress responses in the rat.

PMID- 4348648
TI  - Effects of estrogen treatment on plasma renin parameters in the rat.

PMID- 4348649
TI  - The binding of 18-hydroxydeoxycorticosterone and 18-hydroxycorticosterone to
      mineralocorticoid and glucocorticoid receptors in the rat kidney.

PMID- 4348650
TI  - Pinealectomy and brain myelination.

PMID- 4348651
TI  - Evidence for a new class of corticosterone receptors in the rat kidney.

PMID- 4348652
TI  - Role of pancreatic monoamines in the impaired insulin secretion of the fasting
      state.

PMID- 4348653
TI  - Nuclear receptor-estrogen complex: relationship between concentration and early
      uterotrophic responses.

PMID- 4348654
TI  - Effect of adrenocorticotropic hormone on extracellular adenosine 3',5'
      monophosphate in the hypophysectomized rat.

PMID- 4348655
TI  - The metabolism of perchlorate in the rat.

PMID- 4348657
TI  - Peripheral levels of estrogen in the PMS-primed cycling hamster.

PMID- 4348656
TI  - Effect of hypophysectomy on serum dopamine-beta-hydroxylase activity in rat.

PMID- 4348658
TI  - Ouabain stimulation of  45 CA ++  accumulation in the rat pituitary.

PMID- 4348659
TI  - Hormonal factors influencing ovarian uptake of human chorionic gonadotropin.

PMID- 4348660
TI  - Anomalous prolactin release in vitro in response to cold and its specific
      blockade by a purified hypothalamic-inhibiting factor.

PMID- 4348662
TI  - Discharge plans--the weakest link.

PMID- 4348661
TI  - Characterization of human corneal collagenase.

PMID- 4348663
TI  - Study of cellular inclusion in the human foetal intestinal neuron.

PMID- 4348664
TI  - Prevalence of amoebiasis and other intestinal parasitic infections in a selected
      community.

PMID- 4348666
TI  - Does entrapment neuropathy contribute to nerve damage in leprosy?

PMID- 4348665
TI  - Evaluation of laboratory methods in the detection of E. histolytica and other
      intestinal parasites.

PMID- 4348667
TI  - The use of cord serum and indirect viral immunofluorescence as a method of
      evaluating the immunological specificity of fluorescein-labelled anti-human IgA
      conjugate.

PMID- 4348668
TI  - Coagulation and renal disease.

PMID- 4348670
TI  - [Phenylalanine hydroxylase activity in cell extracts of Anabaena variabilis blue
      gree algae].

PMID- 4348669
TI  - [Characteristics of Micrococcus lysodeikticus membranes in relation to the growth
      phase of the cell culture].

PMID- 4348671
TI  - A comparison of the antilipolytic effects of nicotinic acid, methylisoxazole
      carboxylic acid, methylpyrazole carboxylic acid and insulin in isolated fat
      cells.

PMID- 4348672
TI  - A novel assay for erythrocyte carbonic anhydrase and certain sulfonamide drugs
      employing spin-labels.

PMID- 4348673
TI  - The effect of corticotrophin on the compartmental arrangement of steroids, and
      the control of steroid hormone secretion by the rat adrenal cortex in vitro.

PMID- 4348675
TI  - [Giant cell fascial histiocytosarcoma of the abdominal wall].

PMID- 4348674
TI  - Preparation of oestriol-6-(O-carboxymethyl) oxime and oestrone-6-(carboxymethyl)
      oxime-bovine serum albumin conjugates.

PMID- 4348676
TI  - On the oscillatory potentials of the human electroretinogram in light and dark
      adaptation.

PMID- 4348677
TI  - [Semisynthetic penicillins. X. Synthesis of 6-formamidinopenicillanic acid
      derivatives of cyclic secondary amines].

PMID- 4348678
TI  - A reappraisal of histopathology in lung cancer and correlation of cell types with
      antecedent cigarette smoking.

PMID- 4348679
TI  - [Electrophoretic separation of oxacillin from its inactivation products and their
      separation].

PMID- 4348680
TI  - [Products of partial acid hydrolysis of ristomycin aglycon].

PMID- 4348681
TI  - [Effect of antibiotics on the microaerophilic causative agents of actinomycosis
      in vitro].

PMID- 4348683
TI  - Subcellular location of the kininogenase in the coagulating gland of the guinea
      pig.

PMID- 4348682
TI  - [Results of cooperative clinical studies of the antineoplastic antibiotic
      dactinomycin].

PMID- 4348685
TI  - Studies on cytochrome c. VI. Synthesis of the protected pentadecapeptide
      (sequence 64-81) of Baker's yeast iso-1-cytochrome c.

PMID- 4348686
TI  - Studies on cytochrome c. VII. Synthesis of the protected undecapeptide (sequence
      82-92) of Baker's yeast iso-1-cytochrome c.

PMID- 4348684
TI  - Studies on cytochrome c. V. Synthesis of the protected decapeptide (sequence 57
      66) of Baker's yeast iso-1-cytochrome c.

PMID- 4348687
TI  - Studies on cytochrome c. 8. Synthesis of the protected hexadecapeptide (sequence
      93-108) of Baker's yeast iso-1-cytochrome c.

PMID- 4348688
TI  - Actinomycin D for Wilm's tumor.

PMID- 4348689
TI  - Glomus tumours.

PMID- 4348690
TI  - Vincristine neuropathy. Clinical and electrophysiological observations.

PMID- 4348691
TI  - Phagocytosis by alveolar macrophages: pharmacologic features.

PMID- 4348692
TI  - Retarded clearance of macroaggregated albumin from the lung of asthmatic
      patients.

PMID- 4348693
TI  - Role of viral infection and host factors in acute episodes of asthma and chronic
      bronchitis.

PMID- 4348694
TI  - [Effect of perchlorate and thiocyanate anions on the PBI level and exogenous  125
      I-thyroxine binding to the blood plasma proteins and diaphragm muscle of the rat
      in vivo and in vitro].

PMID- 4348696
TI  - Quantitative analysis of phenolic compounds after thin-layer chromatographic
      separation.

PMID- 4348697
TI  - Thin-layer chromatography for quantitative polychlorinated biphenyl analysis.

PMID- 4348695
TI  - Development of a diploid cell line from fetal rhesus monkey lung for virus
      vaccine production.

PMID- 4348698
TI  - The juvenile angiofibroma of the nasopharynx.

PMID- 4348699
TI  - Effect of hypophysectomy, isletectomy and ACTH on glycemia and hematocrit in the
      bullhead, Ictalurus melas.

PMID- 4348700
TI  - Studies on carcinogenic bifunctional aminoazo dyes. IV. Progressive microscopic
      alternation in the livers of rats fed the carcinogenic bifunctional aminoazo
      dyes: (N', N'-dimethyl-4'-amino)-N-acetyl-N-monomethyl-4-aminoazobenzene.

PMID- 4348701
TI  - Cyclic AMP and its binding protein in the stimulated thyroid of the rat.

PMID- 4348702
TI  - 3',5'-cyclic AMP phosphodiesterases in cytosol of uterine smooth muscle; effects
      of angiotensin.

PMID- 4348703
TI  - Thermoregulatory effects of prostaglandins E 1 , E 2 , F 1   and F 2   in the
      sheep.

PMID- 4348704
TI  - [Myxedema caused by iodine (apropos of a case due to amiodarone)].

PMID- 4348705
TI  - Role of hormones of adrenal cortex and ovaries of pregnant mother in stress
      reaction of rat fetus.

PMID- 4348706
TI  - Tumor immunology.

PMID- 4348708
TI  - Induction of specific unresponsiveness with the aid of Bordetella pertussis.

PMID- 4348707
TI  - Histocompatibility antigens and species-specific antigens.

PMID- 4348709
TI  - Isolation of islets of Langerhans for transplantation.

PMID- 4348710
TI  - Role of virus infections in immunosuppressed renal transplant patients.

PMID- 4348711
TI  - Cytotoxicity of Rous sarcoma cells by lymphoid cells in Japanese quails.

PMID- 4348712
TI  - Depressed allograft immunity in leukemia virus infected mice.

PMID- 4348713
TI  - [Use of dimexide for diseases of the peripheral nervous system].

PMID- 4348714
TI  - Hepatocarcinoma with biliary obstruction. Report of a case and review of the
      literature.

PMID- 4348715
TI  - [Serum alpha-fetoproteins and cancer of the liver].

PMID- 4348716
TI  - The Epstein-Barr Virus (EBV) and Marek's Disease.

PMID- 4348717
TI  - Optimal growth conditions for (Ibadan) strains of Entamoeba histolytica.

PMID- 4348718
TI  - The extra-articular features of rheumatoid arthritis. A systematic analysis of
      127 cases.

PMID- 4348719
TI  - A mucopolysaccharide storage disease with involvement of the renal glomerular
      epithelium.

PMID- 4348720
TI  - Corticosteroidogenesis in isolated adrenal cell preparations of vitamin E
      deficient rats.

PMID- 4348721
TI  - The dynamics of vitamin E transport in the human erythrocyte.

PMID- 4348722
TI  - The cellular mechanisms of vitamin E action: direct and indirect effects of  
      tocopherol on mitochondrial respiration.

PMID- 4348723
TI  - Pathogenesis of demyelination induced by a mouse hepatitis.

PMID- 4348724
TI  - Nuclear DNA in salivary gland tumors. I. Warthin tumors, benign mixed tumors, and
      mucoepidermoid carcinomas.

PMID- 4348725
TI  - Fine structure of Toxoplasma in the human brain.

PMID- 4348726
TI  - Peliosis hepatis. Possible etiologic role of anabolic steroids.

PMID- 4348727
TI  - Nicotinic acid and nicotinamide adenine dinucleotide (NAD) therapy in
      schizophrenia: a review.

PMID- 4348728
TI  - Urea-induced inactivation and dissociation of NAD-specific glutamate
      dehydrogenase of Neurospora and its reversal by substrates.

PMID- 4348729
TI  - The electron paramagnetic resonance spectrum of ferricytochrome c and lysine
      modified derivatives at alkaline pH.

PMID- 4348730
TI  - The pH-induced transition of iodinated ferricytochrome c: electron paramagnetic
      resonance and absorption spectra.

PMID- 4348731
TI  - A comparison of the secretion of two components of very low density lipoproteins
      by perfused rat liver.

PMID- 4348732
TI  - The technique and applications of lymphography.
AB  - The technique of radiographic examination by lymphography of normal lymphatic
      structures regional to the hind limbs is described in the rabbit, dog and rhesus
      monkey. Radiographic appearances of normal lymph nodes and possible applications
      to veterinary science are indicated.Normal lymph node microstructure is
      illustrated using in vivo intralymphatic injection of a brightly colored
      radiopaque silicone rubber. Angiogenesis in active germinal follicles during the
      period of an immune response is displayed. Further applications of the casting
      technique are suggested.

PMID- 4348734
TI  - Effect of morphine on the transport of dopamine into mouse brain slices.

PMID- 4348733
TI  - Collagenolytic activity of gingivae from alloxan-diabetic rats.

PMID- 4348736
TI  - The biphasic response of the isolated guinea-pig ileum by bradykinin.

PMID- 4348735
TI  - Effects of angiotensin-II on myocardial mechanics and contractile state of heart
      muscle.

PMID- 4348737
TI  - Effect of angiotensin on the response to norepinephrine and peri-arterial
      stimulation of the isolated perfused cat terminal ileum.

PMID- 4348738
TI  - N-methyl bicuculline and primary afferent depolarization.

PMID- 4348739
TI  - [Disorders of the central and peripheral nervous system in hyperinsulinism].

PMID- 4348740
TI  - The cytomegaloviruses and the eye.

PMID- 4348741
TI  - Isolation and partial characterization of temperature-sensitive mutants of the
      SAT-1 strain of foot-and-mouth disease virus.

PMID- 4348742
TI  - Characterization of bovine serum lipoproteins.

PMID- 4348743
TI  - Preparation and metabolism of isolated cells from bovine adipose tissue.

PMID- 4348744
TI  - Double antibody radioimmunoassay of renin activity and angiotensin II in human
      peripheral plasma.

PMID- 4348745
TI  - Electron microscopic study of ATPase activity in human brain tumors.

PMID- 4348747
TI  - Myoneural and intermuscular junctions in a molluscan smooth muscle.

PMID- 4348746
TI  - Stereotaxic diagnosis and treatment of intracranial tumors including an initial
      experience with cryosurgery for pinealomas.

PMID- 4348748
TI  - The effect of Triton X-100 on the ultrastructure of ejaculated bovine sperm.

PMID- 4348749
TI  - Lithium-induced ADH resistance in toad urinary bladders.

PMID- 4348750
TI  - The choice of therapy in the treatment of malignancy.

PMID- 4348751
TI  - Amyloid in endocrine tumors.

PMID- 4348752
TI  - The use of drugs in combination for the treatment of cancer: rationale and
      results.

PMID- 4348753
TI  - Marginal vitamin B 12  intake during gestation in the rat has long term effects
      on the offspring.

PMID- 4348754
TI  - [Effect of vitamin D-3 and its metabolites on calcium transport].

PMID- 4348755
TI  - [Change in the ultrastructure of peripheral blood lymphocytes of healthy subjects
      in the process of short-term cultivation with phytohemagglutinin].

PMID- 4348756
TI  - [Effect of environment on sleep].

PMID- 4348757
TI  - [The strange story of a discovery (Otto Loewi)].

PMID- 4348758
TI  - A simple method for estimating H 1  in ESR experiments--the microwave power
      saturation of  -irradiation induced glycylglycine radicals.

PMID- 4348759
TI  - [Comparative statistical study of the evolution of intercritical foci discharges
      induced by various epileptogenic agents].

PMID- 4348760
TI  - [Deprivation of phase IV sleep in epileptic persons].

PMID- 4348761
TI  - [Polygraphic studies of nocturnal sleep of subjects with phobic-obsessive
      neuroses treated with a new benzodiazepine (RO 5-3350)].

PMID- 4348762
TI  - [Various aspects of Lennox's syndrome (report on 100 cases)].

PMID- 4348763
TI  - [Use of synthetic ACTH (Synacthen depot) in the treatment of various forms of
      epilepsy in children].

PMID- 4348764
TI  - Effect of dieldrin on hepatic carbohydrate metabolism and protein biosynthesis in
      vivo.

PMID- 4348765
TI  - Effect of colloidal silicic acid on lecithin bilayers.

PMID- 4348766
TI  - Bilayer lipid membrane as a model for vasopressin, prostaglandin and Ca 2+ 
      effects on water permeability.

PMID- 4348767
TI  - Plasma membranes from fibroblastic cells in culture. Isolation, morphological and
      enzymatic identification.

PMID- 4348768
TI  - Enzyme activities in membranes from three phenotypes of the murine plasmocytoma
      MOPC 173, cultivated in vitro.

PMID- 4348769
TI  - Metabolically controlled hemolysis of chicken erythrocytes.

PMID- 4348770
TI  - Isolation of pig platelet membranes and granules. Distribution and validity of
      marker enzymes.

PMID- 4348771
TI  - Studies of neoplastic myelomonocytic cells in BALB-c mice producing infectious C
      type viruses.

PMID- 4348772
TI  - Ultrastructural studies of histiocyte-tumor cell interactions during tumor
      regression after intralesional injection of Mycobacterium bovis.

PMID- 4348773
TI  - Characterization of glycogen synthetases and phosphorylases in transplantable rat
      hepatomas.

PMID- 4348774
TI  - Enhancement of virus-induced leukemias and sarcomas in F 1  hybrid mice
      inoculated with parental spleen cells.

PMID- 4348775
TI  - Independence of pituitary tumor-mediated suppression of growth hormone secretion
      and cyclic 3',5'-adenosine monophosphate production.

PMID- 4348777
TI  - Sulfated mucopolysaccharide production by synovial sarcoma cells in vivo and in
      tissue culture.

PMID- 4348776
TI  - Suppression of pituitary tumor growth and function by ergot alkaloids.

PMID- 4348779
TI  - [Structural transitions in spin-labeled DNA].

PMID- 4348780
TI  - [Electron transfer between microsomal and mitochondrial membranes].

PMID- 4348781
TI  - [Experience with a new combined open-stereotactic transsphenoidal operation for
      pituitary tumors].

PMID- 4348778
TI  - Chromatographic studies of tyrosyl and phenylalanyl transfer RNA's of liver and
      tumor cells.

PMID- 4348782
TI  - [Cytomegalovirus infection in the adult].

PMID- 4348783
TI  - Effects of age on patterns of enzyme adaptation in male and female rats.

PMID- 4348784
TI  - Octahedral crystals in Phycomyces. II.
AB  - "Phycomyces blakesleeanus" sporangiophores contain octahedral crystals throughout
      their cytoplasm and vacuole. More octahedral crystals were found in the wild-type
      strain G5 (+) than in the beta-carotene-deficient mutant C5 (-), and much more
      than in the mutant C141 (-), which is sensitive to only high light intensity. In
      the wild type, the number of crystals per sporangiophore increased until the
      sporangiophore reached stage IV, and then decreased. Stage I contained the most
      crystals per unit volume. Cultures grown in darkness had the maximum number of
      crystals. Under high light intensity, there was an overall reduction of crystals.
      The crystals are regular octahedrons. The crystals were isolated from the
      sporangiophores by a method of sucrose density-gradient centrifugation. They
      contain nearly 95% protein, are stable in organic solvents, but can be
      solubilized in buffer solution above pH 9.5 and below 2.5. The crystals weakly
      fluoresce with an emission peak at 540 nm, which is affected by irradiation with
      white light. Absorption spectra of freshly prepared crystals show absorption
      maxima around 265-285 nm, 350-380 nm, and 450-470 nm. These absorption peaks for
      the crystals are close to those of the phototropic and light-growth action
      spectra. These data suggest that the crystals may contain a flavoprotein which
      may be the photoreceptor pigment of "Phycomyces".

PMID- 4348785
TI  - Appearance and distribution of ferritin in mouse peritoneal macrophages in vitro
      after uptake of heterologous erythrocytes.
AB  - Mouse peritoneal macrophages have been studied in vitro after ingestion of
      treated rat, rabbit, or sheep erythrocytes. Under light microscopy, phagocytic
      vacuoles persist up to 24 h. Macrophages lose benzidine reactivity about 5 h
      after red cell ingestion, and they become prussian blue positive at 2 days.
      Ultrastructural studies show little or no ferritin in control macrophages not fed
      erythrocytes. In contrast, after red cell ingestion, ferritin is widely
      distributed in the cytoplasmic matrix and in some cytoplasmic granules by 48 h.
      The Golgi complex, pinocytic vacuoles, endoplasmic reticulum, nuclei, and
      mitochondria do not contain ferritin. Between 2 and 4 days, ferritin in
      cytoplasmic granules increases, concomitant with decrease in the ferritin in the
      cytoplasmic matrix. Evidence is presented suggesting that ferritin in the
      cytoplasmic matrix is translocated into cytoplasmic granules by autophagy.
      Polyacrylamide gel studies on macrophages after uptake of red blood cells labeled
      with radioiron confirm that macrophages produce radiolabeled ferritin by 4 days.

PMID- 4348786
TI  - Evidence for recycling of synaptic vesicle membrane during transmitter release at
      the frog neuromuscular junction.
AB  - When the nerves of isolated frog sartorius muscles were stimulated at 10 Hz,
      synaptic vesicles in the motor nerve terminals became transiently depleted. This
      depletion apparently resulted from a redistribution rather than disappearance of
      synaptic vesicle membrane, since the total amount of membrane comprising these
      nerve terminals remained constant during stimulation. At 1 min of stimulation,
      the 30% depletion in synaptic vesicle membrane was nearly balanced by an increase
      in plasma membrane, suggesting that vesicle membrane rapidly moved to the surface
      as it might if vesicles released their content of transmitter by exocytosis.
      After 15 min of stimulation, the 60% depletion of synaptic vesicle membrane was
      largely balanced by the appearance of numerous irregular membrane-walled
      cisternae inside the terminals, suggesting that vesicle membrane was retrieved
      from the surface as cisternae. When muscles were rested after 15 min of
      stimulation, cisternae disappeared and synaptic vesicles reappeared, suggesting
      that cisternae divided to form new synaptic vesicles so that the original vesicle
      membrane was now recycled into new synaptic vesicles. When muscles were soaked in
      horseradish peroxidase (HRP), this tracerfirst entered the cisternae which formed
      during stimulation and then entered a large proportion of the synaptic vesicles
      which reappeared during rest, strengthening the idea that synaptic vesicle
      membrane added to the surface was retrieved as cisternae which subsequently
      divided to form new vesicles. When muscles containing HRP in synaptic vesicles
      were washed to remove extracellular HRP and restimulated, HRP disappeared from
      vesicles without appearing in the new cisternae formed during the second
      stimulation, confirming that a one-way recycling of synaptic membrane, from the
      surface through cisternae to new vesicles, was occurring. Coated vesicles
      apparently represented the actual mechanism for retrieval of synaptic vesicle
      membrane from the plasma membrane, because during nerve stimulation they
      proliferated at regions of the nerve terminals covered by Schwann processes, took
      up peroxidase, and appeared in various stages of coalescence with cisternae. In
      contrast, synaptic vesicles did not appear to return directly from the surface to
      form cisternae, and cisternae themselves never appeared directly connected to the
      surface. Thus, during stimulation the intracellular compartments of this synapse
      change shape and take up extracellular protein in a manner which indicates that
      synaptic vesicle membrane added to the surface during exocytosis is retrieved by
      coated vesicles and recycled into new synaptic vesicles by way of intermediate
      cisternae.

PMID- 4348787
TI  - Enhancement of Sendai virus-mediated cell fusion by cupric ions.
AB  - The effect of divalent cations on cell fusion by concentrated Sendai virus,
      inactivated by beta-propiolactone, was investigated using Vero and mouse L-929
      cells in monolayers. With both cell lines, which are normally resistant to
      exogenous viral fusion, Cu(2+) in sublethal concentrations was found to promote
      polykaryon formation to a marked degree. The simultaneous presence of Cu(2+) and
      virus was required for this effect, which was thought to be related to the
      cytotoxic action of Cu(2+) on the cell membrane. Accordingly, under standard
      conditions and in the absence of virus, leakage of isotopically labeled
      intracellular protein was shown to bear a quantitative relationship to Cu(2+)
      concentration. Concomitant changes in the membrane were seen electron
      microscopically to consist of loss of microvilli and the appearance of numerous
      vesicles on, or adjacent to, the membrane. The relationship of enhanced
      fusibility to these toxic changes was not further elucidated. The fusion
      promoting effect of Cu(2+) far exceeded that of Ca(2+); and other cations tested
      had no effect.

PMID- 4348788
TI  - Growth inhibition of murine tumor cells, in vitro, by puromycin, ( 6 N)O 2 '
      dibutyryl 3',5'-adenosine monophosphate, or adenosine: evidence of commitment for
      cell division.
AB  - The cytostatic effects of puromycm, [(6)N]O(2')-dibutyryl 3',5'-adenosine
      monophosphate, and adenosine on asynchronous and synchronous cultures of the
      murine mastocytoma, P815Y, have been studied. Cell growth was arrested after a
      minimum of one further division. A model is proposed for the inhibition of cell
      division in which the periods of inhibition and growth arrest are separated in
      time by one cell cycle.

PMID- 4348789
TI  - Subcellular morphometric and biochemical analysis of developing rat hepatocytes.
AB  - Livers of rats between the 16th gestational and 100th postnatal day of age were
      subjected to quantitative biochemical and electron microscope, morphometric
      analyses. The amount of total mitochondrial protein per gram of liver remained at
      34% of the adult level throughout the last 4 days of gestation but this was the
      period of rapid rise in the levels of cytochrome c oxidase, aspartate
      aminotransferase, and glutamate dehydrogenase in mitochondria; the nuclear
      fraction also acquired some glutamate dehydrogenase but lost most of it during
      postnatal development. During early postnatal life the amount of mitochondrial
      protein rose in parallel with the levels of cytochrome c oxidase and glutamate
      dehydrogenase but the upsurges of glutaminase and, later, of ornithine
      aminotransferase were accompanied by relatively little change in total
      mitochondrial protein. The surface area of rough endoplasmic reticulum per unit
      volume of hepatocyte cytoplasm (S(v) (RER)) did not change significantly
      throughout the period of development studied. From the 16th day of gestation to
      term the surface area of smooth ER (S(v) (SER)), the volume occupied by
      mitochondria (V(v) (MT)) and their number (N(v) (MT)) remained at 30, 66, and 45%
      of their adult values, respectively. V(v) (MT) and N(v) (MT) attained their
      maximal levels by the 2nd postnatal day and S(v) (SER) between days 2 and 12.
      Mitochondria of adult liver are thus smaller and contain more protein per unit
      volume than do those of fetal liver. After the 12th postnatal day, hepatocytes
      treble their size; they acquire more cytoplasm with additional enzymes but
      without further change in organelle concentration. The data reveal several
      distinct phases in the differentiation of hepatocytes. Each phase can be
      characterized by the extent to which the quantity and composition of various
      subcellular compartments evolve.

PMID- 4348790
TI  - The effect of poly-L-lysine on the uptake of reovirus double-stranded RNA in
      macrophages in vitro.
AB  - The effect of polycations on cultured mouse peitoneal macrophages has been
      examined. Polycations, at concentrations greater than 5 microg/ml, are toxic for
      macrophages) as measured by failure of the cells to exclude vital dyes. At toxic
      concentrations polycations bind in large amounts to nuclei and endoplasmic
      reticulum, while at nontoxic levels polycations bind selectively to the cell
      surface. Nontoxic concentrations of polycations stimulate binding of reovirus
      double-stranded (ds) RNA to the macrophages by forming polycation-dsRNA complexes
      either in the medium or at the cell surface. These complexes enter the cell in
      endocytic vacuoles and are concentrated in secondary lysosomes. Despite exposure
      to the acid hydrolases within this cell compartment, the dsRNA and the polycation
      (poly-L-lysine) are conserved in a macromolecular form within the vacuolar
      system. The mechanism(s) by which the uptake of infectious nucleic acids and the
      induction of interferon by dsRNA are stimulated by polycations are discussed.

PMID- 4348791
TI  - Turnover of transmitter and synaptic vesicles at the frog neuromuscular junction.
AB  - Curarized cutaneous pectoris nerve-muscle preparations from frogs were stimulated
      at 10/s or at 2/s for periods ranging from 20 min to 4 h. End plate potential
      were recorded intracellularly and used to estimate the quantity of transmitter
      secreted during the period of stimulation. At the ends of the periods of
      stimulation the preparations were either fixed for electron microscopy or treated
      with black widow spider venom to determine the quantities of transmitter
      remainind in the terminal. Horseradish peroxidase or dextran was added to the
      bathing solution and used as a tracer to detect the formation of vesicles from
      the axolemma. During 4 h of stimulation at 2/s many new vesicles were formed from
      the axolemma and the quantity of transmitter secreted was several times greater
      than the quantity in the initial store. After this period of stimulation, the
      terminals were severely depleted of transmitter, but not of vesicles, and their
      general morphological organization was normal. During 20 min of stimulation at
      10/s the nerve terminals swelled and were severely depleted both of vesicles and
      of transmitter. During a subsequent hour of rest the changes in morphology were
      largely reversed, many new vesicles were formed from the axolemma and the stores
      of transmitter were partially replenished. These results suggest (a) that
      synaptic vesicles fuse with, and re-form from, the membrane of the nerve terminal
      during and after stimulation and (b), that the re-formed vesicles can store and
      release transmitter.

PMID- 4348792
TI  - Cyclic adenosine monophosphate in phagocytizing granulocytes and alveolar
      macrophages.

PMID- 4348793
TI  - [Functional and serial lipiodol bronchography in the study of bronchiectasic
      disease in children and adolescents (apropos of 665 cases)].

PMID- 4348794
TI  - Transmission of maternal antibodies to Sendai virus in mice and its significance
      in enzootic infection.

PMID- 4348795
TI  - The possible nature of the chance-event in initiation of virus infection at the
      cellular level.

PMID- 4348796
TI  - Genetic studies with herpes simplex virus type 1. The isolation of temperature
      sensitive mutants, their arrangement into complementation groups and
      recombination analysis leading to a linkage map.

PMID- 4348797
TI  - Genetic interactions between temperature-sensitive mutants of types 1 and 2
      herpes simplex viruses.

PMID- 4348798
TI  - A practical and quantitative microtest for determination of neutralizing
      antibodies against Epstein-Barr virus.

PMID- 4348799
TI  - Oncogenicity of non-transforming mutants of avian sarcoma viruses.

PMID- 4348800
TI  - An infectious centres technique for the assay of infectious polyoma virus DNA.

PMID- 4348801
TI  - Comparative studies of the mitochondrial properties of Longissimus dorsi muscles
      of Pietrain and Large White pigs.

PMID- 4348802
TI  - The effect of diarrhoea on low density beta lipoproteins and cholesterol in
      protein calorie malnutrition.

PMID- 4348803
TI  - [Derivation of microphone potentials in mice with "waltzing syndrome" and
      "shakers with syndactylism"].

PMID- 4348804
TI  - [A manageable transistorized nerve stimulation device for the operating room].

PMID- 4348806
TI  - Metaplastic breast carcinoma. Rare form of mammary cancer.

PMID- 4348805
TI  - Low-renin hypertension.

PMID- 4348807
TI  - Hemochromatosis, hepatoma, erythrocytosis, and erythropoietin.

PMID- 4348808
TI  - Gentamicin therapy for liver abscesses due to P. aeruginosa and S. marcescens.

PMID- 4348809
TI  - [The role of hormones, serotonin and cyclic adenosine-3 1 ,5 1 -monophosphate in
      uterine muscle cell contraction].

PMID- 4348810
TI  - Ultraviolet photobleaching of free radicals created in  -irradiated amino acids.

PMID- 4348812
TI  - Electron spin resonance of x-irradiated single crystals of L-threonine at 77
      degrees K.

PMID- 4348811
TI  - Free radicals in irradiated nitro-substituted pyrimidines.

PMID- 4348813
TI  - [Biosynthesis of false proteins: incorporation of p-chlorophenylalanine into
      enzymes of the exocrine pancreas].

PMID- 4348814
TI  - [Retroperitoneal tumors (personal experience)].

PMID- 4348815
TI  - [Staff education for continuity of care].

PMID- 4348816
TI  - Investigation of the metabolism of 3-methoxy-17-epioestriol.

PMID- 4348817
TI  - Effect of FSH on the in vivo uptake of  3 H-testosterone by rat seminiferous
      tubules.

PMID- 4348818
TI  - Studies of the potency of polypeptides with ACTH action by a new method based on
      continuous measurement of plasma corticosterone.

PMID- 4348819
TI  - [Metastasis of hepatocellular cancer to a hypophysis with chromophobe adenoma and
      tumor embolism of the pulmonary artery].

PMID- 4348820
TI  - Ceroid-lipofuscinosis (Batten's disease). First ophthalmological report of
      cytoplasmic inclusions in the Schwann's cell of the sural nerve in two patients
      with an amaurotic familial idiocy.

PMID- 4348821
TI  - Mitochondrial crystals in muscles of a patient with spastic entropion.

PMID- 4348822
TI  - Return of goblet cells after vitamin A therapy in xerosis of the conjunctiva.

PMID- 4348823
TI  - Hydrolytic enzyme substrates. I. Chemical synthesis and characterization.

PMID- 4348824
TI  - Hydrolytic enzyme substrates. II. A new method for measuring periodate.

PMID- 4348825
TI  - Hydrolytic enzyme substrates. 3. Phosphomonoesterase substrates.

PMID- 4348826
TI  - Room-temperature chromatography of nucleic acids on hydroxylapatite columns in
      the presence of formamide.

PMID- 4348827
TI  - Predictability of response to endocrine ablation in advanced breast carcinoma. A
      correlation to estrogen receptor and steroid sulfurylation.

PMID- 4348829
TI  - Model studies on the effects of neutral salts on the conformational stability of
      biological macromolecules. II. Effects of vicinal hydrophobic groups on the
      specificity of binding of ions to amide groups.

PMID- 4348828
TI  - Control of glucose-metabolizing enzymes in preneoplastic rat liver.

PMID- 4348830
TI  - Model studies on the effects of neutral salts on the conformational stability of
      biological macromolecules. 3. Solubility of fatty acid amides in ionic solutions.

PMID- 4348831
TI  - Model studies on the effects of neutral salts on the conformational stability of
      biological macromolecules. IV. Properties of fatty acid amide micelles.

PMID- 4348832
TI  - Interaction of an apolipoprotein (apoLP-alanine) with phosphatidylcholine.

PMID- 4348833
TI  - Oxidative modification of proteins in the presence of ferrous ion and air. Effect
      of ionic constituents of the reaction medium on the nature of the oxidation
      products.

PMID- 4348834
TI  - Respiration of rat lung mitochondria and the influence of Ca 2+  on substrate
      utilization.

PMID- 4348835
TI  - Cyanogen bromide peptides from insoluble skin and dentin bovine collagens.

PMID- 4348836
TI  - Ionic partition between surface and bulk water in a silica gel. A biological
      model.
AB  - Distribution of the biologically important ions between two aqueous phases of
      different structure has been used as a model for ionic distribution in living
      tissue. When other sources of specificity had been eliminated or corrected for,
      surface-oriented water in a silica gel was found to have increased solvent power
      for water-structure-breaking ions and decreased solvent power for water-structure
      making ions; and the relative solubility of an ion in the phase of enhanced
      structure increased regularly with the water-structure-breaking powers of the
      ion. The ionic selectivity was decreased in the presence of urea. The selectivity
      of the gel water for potassium relative to sodium increased to a maximum when the
      gel surface was partially ionized so that distribution of cations was not linked
      to distribution of anions, and then decreased as the surface changed from a
      hydrogen bonding to an ionic surface. It is pointed out that the distribution of
      ions across most living cell membranes is qualitatively the same as that found in
      this silica gel, and it is suggested that the membrane separates two aqueous
      phases of different structure, and that the enhanced structure of cell water
      contributes to the observed ionic distributions.

PMID- 4348837
TI  - Identification of a viral inhibitor in ground beef.

PMID- 4348838
TI  - Rapid extraction and physical detection of polyoma virus.

PMID- 4348839
TI  - Inhibition of polyoma virus development in mouse-hamster heterokaryons.

PMID- 4348841
TI  - [Therapy of shock using vaso- and coagulation-active substances. Behavior of
      tissue oxygen in the dog kidney under the influence of vaso- and coagulation
      active substances].

PMID- 4348840
TI  - The secondary effects of sterilization of the rifampicin by gamma irradiation.

PMID- 4348842
TI  - Interactions between calcium and barium on the spontaneous release of transmitter
      from mammalian motor nerve terminals.

PMID- 4348843
TI  - Correlation between amplitudes and rise times of the miniature endplate
      potentials in frog muscle.

PMID- 4348844
TI  - 'Hallucinogenic drugs and central transmitter substances'.

PMID- 4348845
TI  - A neural network with a background level of excitation in the cat hippocampus.

PMID- 4348846
TI  - Interference of uranyl chloride with structure and function of molecules active
      at the central nervous system level.

PMID- 4348847
TI  - Metabolite levels and enzyme activities in the bovine mammary gland at different
      stages of lactation. I. Metabolite levels related to energy production.

PMID- 4348848
TI  - Cytomegalovirus latency in cultured human cells.

PMID- 4348849
TI  - An investigation of factors influencing the susceptibility of Balb-c 3T3 cells to
      polyoma virus.

PMID- 4348850
TI  - Cyclic variation in susceptibility of Balb-c 3T3 cells to polyoma virus.

PMID- 4348851
TI  - The kinetics of DEAE-dextran-induced cell sensitization to transfection.

PMID- 4348853
TI  - The production of infective virus by SV40-transformed human renal cells.

PMID- 4348852
TI  - Virus antigens on the surface of infected cells: binding and elution of ( 125 I)
      labelled antivirus antibody.

PMID- 4348854
TI  - Distortion of poliovirus particles by fixation with formaldehyde.

PMID- 4348855
TI  - Angiotensin antagonism and antihypertensive activity of phosphodiesterase
      inhibiting agents.

PMID- 4348856
TI  - The behavioral effects of dibutyryl cyclic AMP in mice.

PMID- 4348857
TI  - Estradiol-17 , cyclic AMP and prostaglandins: in vivo and in vitro studies on the
      cervicovaginal epithelium from neonatal mice.

PMID- 4348858
TI  - Estrogens and the menopausal patient.

PMID- 4348859
TI  - Galactose metabolism and its regulation.

PMID- 4348860
TI  - Phosphodiesterase in tongue epithelium: activation by bitter taste stimuli.

PMID- 4348861
TI  - [The influence of interruption of the descending connections of the cortex on the
      effects of extracellular polarization of the lateral geniculate body neurons].

PMID- 4348863
TI  - Significance of clostridia in the female reproductive tract.

PMID- 4348862
TI  - Subcellular distribution, age dependent variation and species differences of
      brain pyridoxal phosphate phosphatase.

PMID- 4348864
TI  - Effect of oral contraceptive therapy on the renin-angiotensin system in
      normotensive and hypertensive women.

PMID- 4348865
TI  - Gonadotropin producing hepatoma.

PMID- 4348866
TI  - Malignant mixed mullerian tumor of the uterine tube.

PMID- 4348867
TI  - Granular cell myoblastoma of the vulva.

PMID- 4348868
TI  - EEG patterns in relation to respiratory rate and body movement in Macaca mulatta.

PMID- 4348869
TI  - Water and sodium chloride intake following microinjections of angiotensin II into
      the septal area of the rat brain.

PMID- 4348870
TI  - Instrumental learning without proprioceptive feedback.

PMID- 4348871
TI  - Effect of adrenocorticotropic hormone on appetitive discrimination learning in
      the rat.

PMID- 4348872
TI  - Arousal from sleep: responsiveness to different auditory frequencies equated for
      loudness.

PMID- 4348874
TI  - The programme of the World Health Organization in medical virology.

PMID- 4348873
TI  - Viruses of the respiratory tract.

PMID- 4348875
TI  - Advances in the serodiagnosis of viral infections.

PMID- 4348876
TI  - Helper-dependent bacteriophage P4: a model satellite virus and its implications
      for animal virology.

PMID- 4348878
TI  - Cytomegaloviruses of man and animals.

PMID- 4348877
TI  - Electron microscopy of viruses in thin sections of cells grown in culture.

PMID- 4348879
TI  - [Significance of brain scanning in neoplasm recurrence].

PMID- 4348880
TI  - [Cytochrome oxidase isoenzymes of the kidneys and blood serum normally and in
      renal insufficiency].

PMID- 4348881
TI  - [Sphingolipid level and the activity of their hydrolases in the organs of rats
      with vitamin A deficiency].

PMID- 4348882
TI  - [The effect of lysozyme, ribonuclease and cytochrome C on the activation of one
      of the blood coagulation factors--the Hageman factor--by adrenaline].

PMID- 4348883
TI  - [Separation of the products of nicotinic acid metabolism on DEAE-cellulose
      paper].

PMID- 4348884
TI  - [Biosynthesis of saturated and unsaturated higher fatty acids in normal
      structures].

PMID- 4348885
TI  - [Ultrastructural bases of vascular permeability].

PMID- 4348886
TI  - [The different picture of organ-specific structures in the carotid body and
      adrenal medulla].

PMID- 4348887
TI  - Rectal ultrastructure in salt- and freshwater mosquito larvae in relation to
      physiological state.

PMID- 4348888
TI  - Filament bundles and contractility of endothelial cells in coronary arteries.

PMID- 4348889
TI  - The ultrastructure of the sinuatrial ring bundle and of the caudal extension of
      the sinus node in the right atrium of the rabbit heart.

PMID- 4348890
TI  - [Treatment of certain aspects of stuttering].

PMID- 4348891
TI  - On the regional metabolism of beef heart ventricles.

PMID- 4348892
TI  - On the descending control of the lumbosacral spinal cord from the "mesencephalic
      locomotor region".

PMID- 4348893
TI  - Estrogen for older women.

PMID- 4348894
TI  - Some pathologic and biochemical aspects of Coats' disease.

PMID- 4348895
TI  - Conservative management of congenital eversion of the eyelids.

PMID- 4348896
TI  - [Acylation of 6-aminopenicillanic acid with levomycetin monoesters].

PMID- 4348897
TI  - [Experimental study of the antibacterial action of 7-chloro-7-deoxylincomycin].

PMID- 4348898
TI  - [Antibiotics in the treatment scheme of peritonitis of appendicular origin].

PMID- 4348899
TI  - The structure of a lipid-cytochrome c membrane.
AB  - In the preceding paper a theory has been developed for the X-ray diffraction
      pattern from a lipid bilayer coated with protein molecules. In this paper the
      validity of the theory is tested. After adding cytochrome c to a preparation of
      lipid vesicles both vesicles and, in lesser amount, a multilayered structure are
      found. The expected cross-interference ripple is evident, and a computed profile
      shows the added protein at the surface of an unchanged lipid bilayer. The results
      confirm the structure proposed by others on the basis of rather indirect chemical
      and X-ray data. Protein coating a lipid bilayer is a possible structure for
      natural membranes. These results demonstrate that globular protein molecules can
      be detected at the surfaces of a lipid bilayer.

PMID- 4348900
TI  - Striate-peristriate cortico-cortical connections in the albino and gray rat.

PMID- 4348901
TI  - Patterns of degeneration after intrinsic lesions of the visual cortex (area 17)
      of the monkey.

PMID- 4348902
TI  - Descending influences on spinocervical tract cell discharges evoked by non
      myelinated cutaneous afferent nerve fibres.

PMID- 4348903
TI  - Interactions of cutaneous myelinated (A) and non-myelinated (C) fibres on
      transmission through the spinocervical tract.

PMID- 4348904
TI  - Effect of calcium and magnesium on spontaneous transmitter release accelerated by
      raised potassium.

PMID- 4348905
TI  - Accumulation of adenosine 3',5'-monophosphate induced by catecholamines in the
      rat superior cervical ganglion in vitro.

PMID- 4348906
TI  - [Morphology and biochemistry of Parkinson's syndrome].

PMID- 4348907
TI  - [Health evaluation of working conditions in the manufacture of
      adrenocorticotropic hormone (ACTH)].

PMID- 4348908
TI  - [Role of free silicon dioxide in the development of chronic dust bronchitis].

PMID- 4348909
TI  - [Radionuclide treatment of lymph node metastases in malignant melanoma].

PMID- 4348911
TI  - Some subcortical determinants of visual cortical excitability in the cat.

PMID- 4348910
TI  - Serum magnesium, serum cholesterol and serum lipoproteins in cases of coronary
      artery disease.

PMID- 4348912
TI  - The effect of pertinent and non-pertinent stimuli on the secretions on
      thyrotropin and corticotropin.

PMID- 4348913
TI  - Platelet aggregation in atopic and normal patients.

PMID- 4348914
TI  - Effect of training on enzyme activity and fiber composition of human skeletal
      muscle.

PMID- 4348915
TI  - A comparison of the major apolipoprotein from pig and human high density
      lipoproteins.

PMID- 4348916
TI  - The purine nucleotide cycle. 3. Oscillations in metabolite concentrations during
      the operation of the cycle in muscle extracts.

PMID- 4348917
TI  - Stimulation of steroid secretion by antimicrotubular agents.

PMID- 4348918
TI  - Adenosine 3',5'-monophosphate in glial tumor cells. Alterations by 5
      bromodeoxyuridine.

PMID- 4348919
TI  - Enzymes of pentose biosynthesis. II. Evidence that the proposed control of
      glucose 6-phosphate dehydrogenase by reduced diphosphopyridine nucleotide is an
      instrumental artifact.

PMID- 4348920
TI  - The purification and properties of the flavoprotein melilotate hydroxylase.

PMID- 4348921
TI  - The mechanism of action of the flavoprotein melilotate hydroxylase.

PMID- 4348923
TI  - Fibrous histiocytoma or xanthoma of the lung with bronchial involvement.

PMID- 4348922
TI  - Pituitary-adrenal interaction and growth of the embryonic avian adrenal gland.

PMID- 4348924
TI  - The role of specific IgM globulin estimations in the diagnosis of acquired
      rubella.

PMID- 4348925
TI  - Systemic corticosteroid therapy.

PMID- 4348926
TI  - Characterization of chemically induced mutations in the ad-I locus of
      Schizosaccharomyces pombe.

PMID- 4348927
TI  - Genetic analysis of purple adenine (ad-3) mutants induced by methyl
      methanesulfonate in Neurospora crassa.

PMID- 4348928
TI  - Production of cyclic inositol phosphate in stimulated tissues.

PMID- 4348929
TI  - Levels of cyclic AMP in sparse and dense cultures of growing and quiescent 3T3
      cells.

PMID- 4348930
TI  - Cyclic AMP and growth of fibroblasts: effect of environmental pH.

PMID- 4348931
TI  - [Effect of hemodilution and dehydration on regional cerebral circulation].

PMID- 4348933
TI  - [Perirenal abscess due to uncommon causes].

PMID- 4348932
TI  - [Epidemiological study of infections due to cytomegaloviruses. I. Serological
      studies of 434 patients with tumors].

PMID- 4348934
TI  - Some factors controlling the secretion of antidiuretic hormone and renin.

PMID- 4348935
TI  - [Carcinoma of the renal pelvis following phenacetin abuse].

PMID- 4348936
TI  - Cylindroma of the sphenoid sinus. A study of two cases.

PMID- 4348937
TI  - Bovine virus diarrhea associated with severe pneumotropism.

PMID- 4348938
TI  - Biochemical lesions of respiratory enzymes and configurational changes of
      mitochondria in vivo. I. The effect of fluoroacetate: a study by phase-contrast
      microscopy and time-lapse cinemicrography.

PMID- 4348940
TI  - [Ultrastructure of the ovary of Viviparus contectus (Millet, 1813) (Gastropoda,
      Prosobranchia). II. Oocytes].

PMID- 4348939
TI  - A radioautographic study of the transport of  125 I-labeled serum lipoproteins in
      rat aorta.

PMID- 4348941
TI  - [Significance of pathologic secretion in the diagnosis of breast carcinoma].

PMID- 4348942
TI  - Quantitative correlation of plasma and myocardial quinidine concentrations with
      biochemical and electrocardiographic changes.

PMID- 4348943
TI  - Altered morphology and increased acid hydrolase content of pulmonary macrophages
      from cigarette smokers.

PMID- 4348944
TI  - Bronchioloalveolar carcinoma. Clinicopathologic relationships, natural history,
      and prognosis in 29 cases.

PMID- 4348945
TI  - Effect of pyrazinamide on nicotinamide adenine dinucleotide glycohydrolase of
      tuberculous host.

PMID- 4348946
TI  - Alveolar cell carcinoma. Diagnosis by lobar lavage.

PMID- 4348947
TI  - Effects of pneumonia on intrapulmonary distribution of inhaled particles.

PMID- 4348948
TI  - Treating friction blisters with alkyl- -cyanoacrylates.

PMID- 4348949
TI  - Multiple cylindromas.

PMID- 4348950
TI  - Carcinoma of mammary crease "simulating basal cell epithelioma".

PMID- 4348951
TI  - [Bronchial adenomas].

PMID- 4348952
TI  - Reticuloendotheliosis virus (strain T). VI. An immunogen versus
      reticuloendotheliosis and Rous sarcoma.

PMID- 4348953
TI  - Avian encephalomyelitis: pathogenesis and histologic features of dorsal root
      ganglia lesions in chicks.

PMID- 4348954
TI  - Studies on fowlpox viruses. I. Plaque formation of fowlpox virus on chick embryo
      cell culture.

PMID- 4348956
TI  - Para-fluorophenylalanine as an inhibitor of parainfluenza 3 virus multiplication.

PMID- 4348955
TI  - Studies on fowlpox viruses. II. Plaque-neutralization test.

PMID- 4348957
TI  - Differences between B. pertussis and propranolol induced histamine
      hypersensitivity in mice.

PMID- 4348958
TI  - I. Pharmacology of angiotensin antagonists.

PMID- 4348959
TI  - II. Pharmacology of angiotensin antagonists.

PMID- 4348960
TI  - Inactivation of exogenous and neural noradrenaline by elastic and muscular
      arteries.

PMID- 4348961
TI  - Some aspects of sarcoidosis.

PMID- 4348962
TI  - Hydroxyproline-rich wall protein (extensin): biosynthesis and accumulation in
      growing pea epicotyls.

PMID- 4348963
TI  - Increased toxicity of double-stranded ribonucleic acid in virus-infected animals.
AB  - Virus-infected mice were significantly more susceptible to the toxic effects of
      double-stranded ribonucleic acid (RNA) than uninfected mice. A dramatic increase
      in mortality was observed after injection of either synthetic
      (polyriboinosinic.polyribocytidylic acid) or natural (mycophage) double-stranded
      RNA in mice infected with Newcastle disease virus (NDV) or vesicular stomatitis
      virus (VSV). With the exception of endotoxin, interferon inducers other than
      double-stranded RNA, such as tilorone-hydrochloride and chlorite-oxidized
      oxyamylose, did not show this increased toxicity in virus-infected animals. The
      increased susceptibility of virus-infected animals to the toxic effects of double
      stranded RNA appears to be related to the levels of interferon induced by the
      virus infection, either systemically, in the blood stream (after inoculation of
      NDV), or locally, in the brain (after infection with VSV).

PMID- 4348964
TI  - Enhancement, by two carboxylic acid interferon inducers of resistance stimulated
      in mice by foot-and-mouth disease vaccine.
AB  - Simultaneous injection of divinyl ether-maleic amhydride (DVE/MA) or itaconic
      acrylic acid and foot-and-mouth disease virus vaccine enhanced the survival of
      infant mice to subsequent injections of virus. This enhanced resistance was
      obtained even with doses of interferon inducers which, when administered alone,
      failed to protect the mice. There was some increase in serum-neutralizing
      antibody in mice 7 days after injection of DVE/MA and vaccine, as compared with
      mice given vaccine alone, but there was no clear connection between antibody
      level and amount of DVE/MA administered.

PMID- 4348965
TI  - In vivo studies with collagenase from Pseudomonas aeruginosa.
AB  - An extracellular protease from Pseudomonas aeruginosa having collagenase activity
      was assayed in vivo. The lethality of the enzyme for white female mice was
      determined by use of intravenous, intraperitoneal, intranasal, and subcutaneous
      routes, respectively. The collagenase exhibited the following 72-hr mean lethal
      dose values: intranasally, 55 collagenase units; intraperitoneally, 148
      collagenase units; and intravenously, 288 collagenase units. In the
      concentrations tested, no lethality was obtained when the subcutaneous route was
      employed. Gross and microscopic studies revealed that the collagenase was capable
      of eliciting a variety of tissue responses in mice depending upon its route of
      administration. Intranasal instillation resulted in confluent pulmonary
      hemorrhage, whereas intraperitoneal injections resulted in severe abdominal
      hemorrhage with foci on the intestinal serosa. Intravenous injections elicited
      abdominal hemorrhage and petechial hemorrhage with focal necrosis of the lungs,
      whereas subcutaneous injections resulted in necrotic, ulcerating lesions.

PMID- 4348967
TI  - Assay of cortisol, corticosterone, 11-deoxycortisol and cortisone in ovine
      peripheral and adrenal venous plasma.

PMID- 4348966
TI  - Pathogenesis of herpetic neuritis and ganglionitis in mice: evidence for intra
      axonal transport of infection.
AB  - The pathogenesis of acute herpetic infection in the nervous system has been
      studied following rear footpad inoculation of mice. Viral assays performed on
      appropriate tissues at various time intervals indicated that the infection
      progressed sequentially from peripheral to the central nervous system, with
      infectious virus reaching the sacrosciatic spinal ganglia in 20 to 24 hr. The
      infection also progressed to ganglia in mice given high levels of anti-viral
      antibody. Immunofluorescent techniques demonstrated that both neurons and
      supporting cells produced virus-specific antigens. By electron microscopy,
      neurons were found to produce morphologically complete virions, but supporting
      cells replicated principally nucleocapsids. These results are discussed in the
      context of possible mechanisms by which herpes simplex virus might travel in
      nerve trunks. They are considered to offer strong support for centripetal
      transport in axons.

PMID- 4348969
TI  - Morphological responses to corticotrophin and cyclic AMP by adult rat
      adrenocortical cells in monolayer culture.

PMID- 4348968
TI  - Distribution of adrenocorticotrophic hormone-stimulated adenylate cyclase in the
      adrenal cortex.

PMID- 4348970
TI  - The steroidogenic response of adult rat adrenocortical cells in monolayer
      culture.

PMID- 4348971
TI  - A comparison of procedures for the isolation of adrenocorticotrophin from human
      pituitary glands.

PMID- 4348972
TI  - Virus-like particles associated with the mycoplasmas of clover phyllody in the
      plant and in the insect vector.

PMID- 4348973
TI  - Decline in mixed lymphocyte reactivity of spleen cells from aged mice of a long
      lived strain.

PMID- 4348974
TI  - Lymphocyte activation. 3. The prolonged requirement for mitogen in
      phytohaemagglutinin- and concanavalin A-stimulated cultures.

PMID- 4348975
TI  - Host defenses during primary Venezuelan equine encephalomyelitis virus infection
      in mice. I. Passive transfer of protection with immune serum and immune cells.

PMID- 4348976
TI  - Oat cell carcinoma of bronchus associated with carcinoid syndrome and intestinal
      carcinoid.

PMID- 4348977
TI  - Congenital epulis.

PMID- 4348978
TI  - Cervical cancer.

PMID- 4348979
TI  - Development and characteristics of the histamine-induced accumulation of cyclic
      AMP in the rabbit cerebral cortex.

PMID- 4348980
TI  - Modulators of glutaminase activity.

PMID- 4348981
TI  - Purification and characterization of an NADH-linked aldehyde reductase from
      bovine brain.

PMID- 4348983
TI  - Angiotensinase activity in rat and dog brain.

PMID- 4348982
TI  - Distribution and properties of angiotensin converting enzyme of rat brain.

PMID- 4348984
TI  - An ATP pool associated with adenyl cyclase of brain tissue.

PMID- 4348985
TI  - [Herpes simplex virus and its infections].

PMID- 4348986
TI  - Serum inhibitors of A 2 -Hong Kong influenza virus haemagglutination.

PMID- 4348987
TI  - Interaction of Sendai virus with human erythrocytes: a system for the study of
      membrane fusion.

PMID- 4348989
TI  - Viral infections and demyelinating diseases.

PMID- 4348988
TI  - Lung cancer in chloromethyl methyl ether workers.

PMID- 4348991
TI  - [The prostaglandins].

PMID- 4348990
TI  - Treatment of tuberculosis today in Nebraska.

PMID- 4348992
TI  - [Radiotherapy of rectal carcinomaa].

PMID- 4348993
TI  - [Experimental intrauterine transmission of adenoviruses].

PMID- 4348994
TI  - [Cytochemical indices of luekocyte enzyme activity in patients with rheumatic
      defects].

PMID- 4348995
TI  - Responsivity in infants during sleep.

PMID- 4348996
TI  - Cerebral responses to flickering light in clinical research.

PMID- 4348997
TI  - Effect of diphenylhydantoin on paroxysmal EEG activity induced by cortical cobalt
      focus.

PMID- 4348998
TI  - Diagnosis and management of hyperlipoproteinemia in infants and children.

PMID- 4348999
TI  - Pressure reversal of anesthesia: the extent of small-molecule exclusion from spin
      labeled phospholipid model membranes.

PMID- 4349000
TI  - The electromyogram and the mechanical response of indirectly stimulated muscle in
      anesthetized man following curarization.

PMID- 4349001
TI  - Covalent and noncovalent control of glycogen synthesis.

PMID- 4349002
TI  - Glycogen metabolism during differentiation in Dictyostelium discoideum.

PMID- 4349003
TI  - Preliminary studies of the neurones of Auerbach's plexus using intracellular
      microelectrodes.

PMID- 4349004
TI  - Factors determining colony forming efficiency in agar suspension cultures.

PMID- 4349005
TI  - The structure and function of adrenal autotransplants.

PMID- 4349006
TI  - On the neuronal organization of the acoustic middle ear reflex. A physiological
      and anatomical study.

PMID- 4349007
TI  - Quantitative neural and psychophysical data for cutaneous mechanoreceptor
      function.

PMID- 4349008
TI  - Nature of the midbrain influences upon thalamic neurons.

PMID- 4349009
TI  - The quantitative relation between extracellular calcium and acetylcholine release
      at the frog neuromuscular junction.

PMID- 4349010
TI  - A comparison of the binding of ( 14 C) -aminobutyric acid and ( 3 H)acetylcholine
      to particulate fractions of 4 regions of rat brain in the presence of 40 mM NaCl.

PMID- 4349011
TI  - A possible role for mast cells in controlling the diameter of arterioles on the
      surface of the brain.

PMID- 4349012
TI  - Dynamic single unit simulation of a realistic cerebellar network model.

PMID- 4349014
TI  - The study of cellular "microexudates" by ellipsometry and their relationship to
      the cell coat.

PMID- 4349013
TI  - Periodate-induced lymphocyte transformation. II. Character of response and
      comparison with phytohemagglutinin and pokeweed mitogen stimulation.

PMID- 4349015
TI  - Use of a serum gradient for separation of polykaryocytes from single cells after
      fusion with Sendai virus.

PMID- 4349016
TI  - Comparative effects of caffeine, its analogues and calcium deficiency on
      cytokinesis.

PMID- 4349017
TI  - Morphology and growth rate changes in Chinese hamster cells cultured in presence
      of sodium butyrate.

PMID- 4349018
TI  - Inhibition of DNA synthesis of synchronized cells by liver extracts acting in G1
      phase.

PMID- 4349019
TI  - Resistance of amoeba cytoplasm to cycloheximide.

PMID- 4349020
TI  - Release of fibrinolytic activators from human tumours cultured in vitro.

PMID- 4349021
TI  - Cyclic AMP of blood platelets: accumulation in organelles storing 5
      hydroxytryptamine and ATP.

PMID- 4349022
TI  - Cyclic AMP: its effect on an estrogen-sensitive antigen in organ cultures of the
      cervicovaginal epithelium from neonatal mice.

PMID- 4349023
TI  - Possible role of glucose-6-phosphate in the anti-anaphylactic mechanism mediated
      by cyclic AMP.

PMID- 4349024
TI  - A roentgenometric study of the process of ossification of the human sternum.

PMID- 4349025
TI  - A new analysis of neuronal interspike intervals based on inequality tests.

PMID- 4349026
TI  - A multistage transduction model for information processing in the nervous system.

PMID- 4349028
TI  - Selection of respiratory mutants of Neurospora crassa.
AB  - A method is described that permits the isolation of mutants that are defective in
      mitochondrial respiration. The techniques of inositol-less death and overlay with
      2,3,5-triphenyl-2H-tetrazolium chloride are utilized to select for mutant
      colonies. Colonies that survive inositol-less death and fail to reduce the
      tetrazolium dye are then tested polarographically for cyanide-sensitive
      respiration. A preliminary characterization of three mutants obtained by this
      method is presented. The mutants have been characterized by their cyanide
      sensitive respiration rate, growth rate, the state III respiration rate of
      isolated mitochondria, inhibition of the respiration of isolated mitochondria by
      cyanide and antimycin A, and cytochrome spectra. All of the mutants described
      differ from the parent strain in some of these aspects.

PMID- 4349027
TI  - Recognition of a gene involved in the regulation of nicotinamide adenine
      dinucleotide biosynthesis.
AB  - Mutations affecting the biosynthesis of quinolinic acid, a precursor of
      nicotinamide adenine dinucleotide (NAD) in Escherichia coli K-12, are either near
      min 17 (nadA mutants) or near min 49 on the chromosome. These nad mutants all
      exhibit a phenotypic requirement for NAD or one of its immediate precursors. The
      mutants with lesions near min 49 can be separated into two groups based on in
      vitro complementation analysis. One group (nadB) exhibits complementation with
      nadA mutants, whereas the other group fails to do so. The latter group is
      tentatively designated nadR based on its regulation of the unlinked nadA gene.
      The nadR gene maps adjacent to nadB between purI and tyrA.

PMID- 4349029
TI  - Saccharomyces mutants with invertase formation resistant to repression by
      hexoses.
AB  - Production of invertase by many strains of yeast is repressed in the presence of
      hexoses. This phenomenon interferes with studies on the secretion of invertase
      and with the preparation of large quantities of the enzyme for examination of its
      chemical and physical characteristics. Saccharomyces strain 303-67, a diploid
      carrying the single gene SUC-2 for (hexose repressible) invertase production, was
      subjected to ultraviolet irradiation. No single-step mutations to high level
      resistance were detected. By a two-step irradiation process mutants were obtained
      with differing degrees of resistance. The biochemical and genetic characteristics
      of these mutants are summarized with particular emphasis on FH4C (the most
      resistant). Although the steady state level of cyclic 3', 5'-adenosine
      monophosphate (cyclic AMP) was usually slightly higher in cells grown in low-
      rather than in high-glucose media, the level of cyclic AMP was not correlated
      with the sensitivity of invertase synthesis to glucose repression. In mutant
      FH4C, 1 to 2% of the total cell protein is present as invertase; synthesis of
      alpha-glucosidase is also resistant to repression by hexoses. This mutant does
      not sporulate and is probably a haploid of a-mating type with low frequency of
      conjugation and poor viability of conjugants. Mutants 1016 and 1710 are
      substantially resistant to hexose repression and still sporulate well. They may
      be useful for genetic analysis of hexose resistance.

PMID- 4349030
TI  - Physiological modifications in the production and repair of methyl methane
      sulfonate-induced breaks in the deoxyribonucleic acid of Escherichia coli K-12.
AB  - The medium in which Rec(+) strains of Escherichia coli K-12 are grown affected
      their sensitivity to treatment with methyl methane sulfonate (MMS). Rec(+) cells
      grown to the stationary phase in glucose-enriched nutrient broth (GNB) were more
      resistant to MMS than cells grown in nutrient broth (NB). The repair of MMS
      induced breaks (or alkali-labile bonds) in the deoxyribonucleic acid (DNA) from
      E. coli K-12 strains AB1157, AB1886 uvrA6, and SR111 recA13 recB21 grown in GNB
      and NB media was examined by means of alkaline sucrose gradient centrifugation.
      It appeared that essentially all of the repair of breaks that occurred, as
      evidenced by an increase in "molecular weight," took place within 10 min after
      treatment with MMS under our conditions. Cell survival was highest in cells for
      which the size of the DNA after the post-treatment incubation was the largest.
      The largest DNA after post-treatment incubation was found in Rec(+) cells grown
      in GNB medium. The results suggest that these cells may have an enhanced capacity
      for repairing breaks in DNA.

PMID- 4349031
TI  - Fate of transforming deoxyribonucleic acid after uptake by competent Bacillus
      subtilis: phenotypic characterization of radiation-sensitive recombination
      deficient mutants.
AB  - A collection of 16 isogenic recombination-deficient strains of Bacillus subtilis
      isolated on the basis of sensitivity to methyl methane sulfonate (MMS) or
      mitomycin C (MC) were characterized phenotypically. All were found to be somewhat
      sensitive to ultraviolet irradiation, MC, and MMS. The mutants were all blocked
      in "late" steps in the transformation process and were provisionally grouped into
      four categories on the basis of the various properties examined. Class I mutants
      were deficient in transformation and heterologous transduction with phage PBS1
      but were transducible with homologous donors at nearly the wild-type frequency.
      They were blocked in donor-recipient complex (DRC) formation but formed
      essentially normal amounts of double-strand fragments (DSF) and single-strand
      fragments (SSF). The class IIa strain was deficient in transformation and PBS1
      transduction, and formed DRC which was normal by all available physical and
      biological criteria. Class IIb mutants were deficient in transformation and PBS1
      transduction, and failed to form DRC. They did produce DSF and SSF. Class III
      mutants were deficient in transformation, were normal in PBS1 transduction, and
      formed DRC which was physically indistinguishable from that of the Rec(+) parent
      although with slightly lowered donor-type transforming activity. Class IV strains
      were deficient in PBS1 transduction but were transformed at nearly the wild-type
      efficiency. None of the mutant strains was deficient in the adenosine
      triphosphate-dependent deoxyribonuclease.

PMID- 4349033
TI  - CO 2  reduction to formate in Clostridium acidi-urici.
AB  - Cell-free lysates of Clostridium acidi-urici catalyze the reduction of CO(2) to
      formate in the presence of reduced ferredoxin and nicotinamide adenine
      dinucleotide, reduced form.

PMID- 4349032
TI  - Methanol metabolism in pseudomonad C.
AB  - Cell suspensions of pseudomonad C, a bacterium capable of growth on methanol as
      sole carbon source, were able to oxidize methanol, formaldehyde, and formate,
      although the rates of oxidation for the latter two compounds were much slower.
      The latter compounds also could not serve as sole carbon sources. Through the use
      of labeled compounds, it was shown that in the presence of methanol,
      formaldehyde, formate, and bicarbonate were incorporated into trichloroacetic
      acid-precipitable material. Hexose phosphate synthetase activity was found,
      indicating the assimilation of methanol via an allulose pathway. No
      hydroxypyruvate reductase activity was found, nor was any complex membrane
      structure observed. Such a combination of characteristics has been observed in an
      obligate methylotroph (Pseudomonas W1), but pseudomonad C can utilize a variety
      of non-methyl substrates.

PMID- 4349034
TI  - Oligosaccharides produced by acetolysis of blood group active(A + H)sulfated
      glycoproteins from hog gastric mucin.

PMID- 4349036
TI  - Kinetics of the glucose 6-phosphate-glucose exchange activity and glucose
      inhibition of glucose 6-phosphatase of intact and disrupted rat liver microsomes.

PMID- 4349035
TI  - The crystal structure of a riboflavin-metal complex. Ribofalavin silver
      perchlorate hemihydrate.

PMID- 4349038
TI  - Steroidogenesis and cyclic adenosine 3',5'-monophosphate accumulation in rat
      adrenal cells. Divergent effects of adrenocorticotropin and its o-nitrophenyl
      sulfenyl derivative.

PMID- 4349037
TI  - Evaluation of the rate-determining steps and the relative magnitude of the
      individual rate constants for the hydrolytic and synthetic activities of the
      catalytic component of liver microsomal glucose 6-phosphatase.

PMID- 4349040
TI  - Mitochondrial D- -hydroxybutyrate dehydrogenase. IV. Kinetic analysis of reaction
      mechanism.

PMID- 4349039
TI  - Human adenine phosphoribosyltransferase. Purification, subunit structure, and
      substrate specificity.

PMID- 4349041
TI  - Mitochondrial-cytosolic interactions in perfused rat heart. Role of coupled
      transamination in repletion of citric acid cycle intermediates.

PMID- 4349042
TI  - Some properties of the catalytic sites of imidazoleglycerol phosphate dehydratase
      histidinol phosphate phosphatase, a bifunctional enzyme from Salmonella
      typhimurium.

PMID- 4349043
TI  - Collagenase and hyaluronidase stimulation by dibutyryl adenosine cyclic 3':5'
      monophosphate.

PMID- 4349044
TI  - Biochemical observations in functioning human thyroid adenomas.

PMID- 4349045
TI  - Urinary excretion of cyclic-3',5'-adenosine monophosphate in hyperthyroidism.

PMID- 4349046
TI  - New in vitro tests to detect the thyroid stimulator in sera from hyperthyroid
      patients by measuring colloid droplet formation and cyclic AMP in human thyroid
      slices.

PMID- 4349048
TI  - A comparison of the  -melanocyte-stimulating hormone and corticotropin response
      to hypoglycemia.

PMID- 4349047
TI  - Male pseudohermaphroditism due to testicular 17 -hydroxysteroid dehydrogenase
      deficiency.

PMID- 4349049
TI  - Plasma cortisone concentration as measured by radioimmunoassay.

PMID- 4349050
TI  - Syndrome of hyporeninemic hypoaldosteronism and hyperkalemia in renal disease.

PMID- 4349051
TI  - Proinsulin and insulin release with a human insulinoma and adjacent
      nonadenomatous pancreas.

PMID- 4349052
TI  - Alterations in lipid composition of plasma lipoproteins during deposition of egg
      yolk.
AB  - The profiles of total lipids and of the molecular species of individual lipid
      classes were compared among corresponding lipoproteins of plasma and yolk of the
      laying hen. A close qualitative correspondence was found in the makeup of the
      molecular species of glycerophospholipids and triglycerides of the very low
      density lipoproteins and the high density lipoproteins of plasma and yolk. There
      was a lower proportion of the trienoic triglycerides and of the dienoic
      glycerophospholipids in the egg yolk than in the plasma lipoproteins, and the
      greatest differences (20-30%) were noted between the high density lipoproteins.
      It was also observed that the plasma high density lipoproteins lost their
      cholesteryl esters upon entering the yolk. On the basis of these and comparable
      analyses of the plasma lipoproteins of the nonlaying hen, it is concluded that
      the laying hen synthesizes specific lipoproteins for deposition in the yolk, and
      these are carried in plasma and selectively transferred to the developing ovum
      without significant equilibration with the other plasma lipoproteins.

PMID- 4349053
TI  - Biosynthesis of lymph and plasma lipoprotein apoproteins by isolated perfused rat
      liver and intestine.
AB  - The ability of rat intestine and liver to synthesize the various apoproteins of
      plasma lipoproteins was investigated. After the individual isolated organs were
      perfused with blood containing [(3)H]lysine, chylomicrons plus very low density
      lipoproteins (VLDL), low density lipoproteins (LDL), and high density
      lipoproteins (HDL) were isolated from the perfusates and the intestinal lymph.
      After lipoprotein delipidation, apoproteins were separated by polyacrylamide gel
      electrophoresis and the (3)H content was determined. Livers incorporated
      [(3)H]lysine into all apoprotein bands of VLDL and HDL. The (3)H content was
      greater in large proteins that remained in the stacking gel (group I,
      predominantly beta-apoprotein) than in proteins with apparent molecular weights
      near 50,000 (group II) or in the smaller peptides (molecular weights near 10,000,
      group III). In the intestine, (3)H was incorporated into group I and, in larger
      amounts, into group II apoproteins of lymph VLDL. No labeled VLDL appeared in the
      perfusate. (3)H was also incorporated into group II apoproteins of lymph and
      perfusate HDL. Significantly, no [(3)H]lysine was found in the group III peptides
      of any lymph or intestinal perfusate lipoproteins. Since these peptides were
      always present in VLDL from mesenteric lymph collected in vivo, the results
      suggest that nascent VLDL of gut origin acquires group III peptides from other
      lipoproteins that penetrate lymph from plasma.

PMID- 4349055
TI  - Phospholipid metabolism in light and dark adapted excised retina.

PMID- 4349054
TI  - Lipolysis and reesterification: effects of some inhibitors of adenosine 3',5'
      cyclic monophosphate phosphodiesterase.
AB  - Theophylline and three lipolytic agents, 2,5-bis(2-chloroethylsulfonyl)-pyrrole
      3,4-dicarbonitrile (substituted pyrrole), 2,4-diamino-6-butoxy-s-triazine
      (substituted triazine), and 2,3-dihydro-5,6-dimethyl-3-oxo-4
      pyridazinecarbonitrile (substituted pyridazine), stimulate basal lipolysis in
      adipose tissue in vitro. They also cause an increased release of free fatty
      acids, but not glycerol, from adipose tissue in which lipolysis is already
      maximally stimulated by epinephrine. The four compounds also inhibit cyclic AMP
      phosphodiesterase and the conversion of [1-(14)C]glucose to (14)CO(2). Evidence
      is presented that free fatty acids accumulate as the result of inhibited
      reesterification. The substituted pyridazine and triazine, but not the pyrrole,
      elevate plasma free fatty acids after oral or intraperitoneal administration in
      rats.

PMID- 4349056
TI  - Evidence for involvement of Ca 2+  in the incorporation of  32 P i  into the
      phosphatidylinositol of rat diaphragm.

PMID- 4349058
TI  - Analysis of background firing of single sympathetic preganglionic neurons of cat
      cervical nerve.

PMID- 4349057
TI  - Action of neuraminidase (EC 3.2.1.18) from Clostridium perfringens on brain
      gangliosides in the presence of bile salts.

PMID- 4349059
TI  - A comparison of electrical properties of neurons in Necturus retina.

PMID- 4349060
TI  - Computer-aided statistical analysis of the scintillation camera 131I-hippuran
      renogram.

PMID- 4349061
TI  - Hypoglycemia in infancy and childhood. II.

PMID- 4349062
TI  - The association of viral and bacterial respiratory infections with exacerbations
      of wheezing in young asthmatic children.

PMID- 4349063
TI  - Metabolic and biochemical studies in fructose 1,6-diphosphatase deficiency.

PMID- 4349064
TI  - [Aging of the bronchial tree and the bronchial vascular system. 2. Changes in the
      bronchial vascular system tone due to aging].

PMID- 4349065
TI  - [Composition of lipoprotein--influence of high carbohydrate and high fat diet on
      the composition of very low density lipoprotein].

PMID- 4349067
TI  - Scoliosis treatment. Skeletal maturity evaluation.

PMID- 4349066
TI  - Ultrastructural changes in adrenal, spleen and liver tissue, induced by
      chlorphentermine.

PMID- 4349068
TI  - [Isotope studies in childhood tumors].

PMID- 4349069
TI  - [Essential hypertension: biochemical analysis--selective treatment].

PMID- 4349071
TI  - [Remote results of surgical treatment of insulin-producing tumors of the
      pancreas].

PMID- 4349070
TI  - [Treatment of Itsenko-Cushing disease (review of the literature)].

PMID- 4349074
TI  - [Cell changes in the rat adrenal cortex during repeated administration of ACTH].

PMID- 4349072
TI  - [Effect of hormones on bone metabolism].

PMID- 4349075
TI  - Immunological aspects of silicosis: possible implications.

PMID- 4349073
TI  - [Morphological aspects of the problem of hypophyseal regulation of the glomerular
      zone of the adrenal gland. I. Reaction of glomerular cells to ACTH and
      hypophysectomy].

PMID- 4349076
TI  - [Statement of the possible role of adenyl cyclase system and cyclic adenosine
      monophosphate in the carcinogenesis process].

PMID- 4349077
TI  - [Hereditary forms of rickets].

PMID- 4349078
TI  - [Adrenocortical activity in piglets at weaning in comparison with exogenous
      stimulation with ACTH].

PMID- 4349079
TI  - [The concentration of cytotoxins in rat serum during the development of ascitic
      tumors].

PMID- 4349080
TI  - [A rapid method of inducing liver tumors in rats].

PMID- 4349081
TI  - Carcinomas of the anorectal region of extramucosal origin with special reference
      to the anal ducts.

PMID- 4349082
TI  - Angiosarcoma following radical mastectomy. Report on two cases.

PMID- 4349083
TI  - Mechanisms of central transmission of respiratory reflexes.
AB  - Several types of respiratory reflex actions can be discerned according to the
      reactions of typical respiratory neurons in the efferent part of the central
      rhythmogenic structure. Whereas respiration runs closely parallel with
      inspiratory neuron activity the behaviour of expiratory neurons cannot be derived
      from the resulting reflex changes of respiration. So expiratory apnoea can be
      combined with continuous activity or with inactivation of expiratory neurons.
      Extracellular records from a closed uniformly reacting population of expiratory
      neurons and from neighbouring reticular neurons allowed experimental
      differentiation between different types of central respiratory reflex actions. In
      experiments on anaesthetized dogs the responses to chemoreceptor and baroreceptor
      excitation and to pulmonary inflation were investigated. Chemoreceptor excitation
      leads to activation of inspiratory, expiratory, and reticular neurons, whereas
      the baroreceptor afferents act in the opposite direction. In contrast moderate
      lung inflation causes more specific effects: activation of expiratory neurons,
      inactivation of inspiratory neurons. But if a certain degree of lung inflations
      is exceeded a more general inhibition of both inspiratory and expiratory neurons
      takes place. These results only apply to the "typical" respiratory neurons. The
      principles used to distinguish between the different types of reflexes are
      proposed for a basis of classification also of other neural, chemical or
      pharmacological influences on breathing.

PMID- 4349086
TI  - [Introductory remarks to the 4th seminar on amebiasis].

PMID- 4349084
TI  - The significance of cytoplasmic inclusions in late infantile and juvenile
      amaurotic idiocy. An ultrastructural study.

PMID- 4349085
TI  - Granular cell myoblastoma of stomach.

PMID- 4349088
TI  - [Juxtanuclear spherules of Entamoeba histolytica. Morphological and dynamic
      study].

PMID- 4349087
TI  - [Biological relations between Entamoeba histolytica and other cells. I. Ameba
      leukocyte association complex].

PMID- 4349089
TI  - [Pinocytosis as anabolic expression of Entamoeba histolytica].

PMID- 4349090
TI  - [Phagocytosis of human erythrocytes by Entamoeba histolytica].

PMID- 4349091
TI  - [Enzymatic activity of Entamoeba histolytica in experimental lesions in rabbits].

PMID- 4349092
TI  - [Erythrophagocytosis by Entamoeba histolytica].

PMID- 4349093
TI  - [Short range action of inactivated hyperimmune human serum on the trophozoite of
      Entamoeba histolytica].

PMID- 4349094
TI  - [Histopathological test of liver lesions in hamsters inoculated with an axenic
      culture of Entamoeba histolytica].

PMID- 4349095
TI  - [Sequence of amebic hepatic lesions in the rabbit].

PMID- 4349096
TI  - [Production of amebic meningoencephalitis in the rabbit].

PMID- 4349097
TI  - [Advances in the counter-immuno-electrophoresis technic for the serologic study
      of amebiasis].

PMID- 4349098
TI  - [Serologic survey in children of Mexico City. VII. Study of antibodies against
      Entamoeba histolytica].

PMID- 4349099
TI  - [Current status of the radiological diagnosis of amebiasis].

PMID- 4349100
TI  - [Development of scintillography in the diagnosis of amebic liver abscess].

PMID- 4349101
TI  - [Medical treatment of amebiasis].

PMID- 4349102
TI  - [Surgical treatment of invasive amebiasis].

PMID- 4349103
TI  - [Hemodynamic and cardiovascular studies in patients with severe hepatic amebiasis
      and state of shock. Preliminary report].

PMID- 4349105
TI  - The seroepidemiology of amebiasis.

PMID- 4349104
TI  - [Studies on the viruses of Entamoeba histolytica: a progress report].

PMID- 4349107
TI  - Trial of gaviscon in the treatment of gastro-oesophageal reflux of infancy.

PMID- 4349106
TI  - Hyperlipoproteinaemia in childhood.

PMID- 4349108
TI  - Proton translocation by rat liver mitochondria with quinones as terminal
      acceptors.

PMID- 4349109
TI  - Bases methylated in vitro by cell-free extracts of adenovirus-18-induced tumours.
AB  - The tRNA methylase activity in vitro of adenovirus-18-induced tumour was studied.
      The activity expressed per mg of protein was the same for extracts of tumours
      induced by either adenovirus-12 or adenovirus-18. The methylated bases isolated
      after incubation with extract from adenovirus-18-induced tumour were N(1)
      methylguanine, 1-methyladenine, 3-methyladenine and N(6)-methyladenine.

PMID- 4349110
TI  - Differences in the patterns of methylation in rat liver ribosomal ribonucleic
      acid after reaction in vivo with methyl methanesulphonate and NN
      dimethylnitrosamine.
AB  - 1. rRNA was isolated from rat liver at short intervals after the intraperitoneal
      injection of [(14)C]methyl methanesulphonate (50mg/kg) or NN
      di[(14)C]methylnitrosamine (2mg/kg). These doses were chosen to minimize the
      effects of toxicity. 2. The following methods of hydrolysis of [(14)C]methylated
      rRNA were employed: enzymic digestion to nucleosides at pH8; alkaline hydrolysis
      and conversion into nucleosides; acid hydrolysis to bases. 3. The methylation
      products were analysed by chromatography on columns of Dowex-50 (H(+) form) and
      Dowex-50 (NH(4) (+) form). 4. With both methylating agents the principal product
      of methylation was 7-methylguanine. Differences were obtained, however, in the
      molar proportions of the minor bases 3-methylcytosine, 1-methyladenine and 7
      methyladenine. Methylation at the O-6 position of guanine was a significant
      feature of rRNA obtained from the NN-di[(14)C]methylnitrosamine-treated animals
      but was not detected in rRNA after treatment with [(14)C]methyl
      methanesulphonate.

PMID- 4349111
TI  - The mode of action of adenosine 3':5'-cyclic monophosphate in mammalian islets of
      Langerhans. Preparation and properties of islet-cell protein phosphokinase.
AB  - 1. A protein was demonstrated in mammalian islets of Langerhans that after
      purification appeared as a single component possessing both cyclic-AMP (adenosine
      3':5'-cyclic monophosphate)-binding and cyclic-AMP-dependent protein
      phosphokinase activities. 2. The protein had an intrinsic association constant
      for cyclic AMP of 1.15x10(-8)m, which was similar to the K(m) for cyclic AMP
      (1.11x10(-8)m) of the protein phosphokinase activity. 3. Incubation of the
      protein in the presence of cyclic AMP resulted in its dissociation into cyclic
      AMP-independent protein phosphokinase (catalytic) and cyclic-AMP-binding
      (receptor) subunits, which could be separated on Sephadex G-200. 4. The cyclic
      AMP-dependent protein phosphokinase was capable of phosphorylating a variety of
      proteins, the most readily phosphorylated being histone, casein and protein
      components of sub-cellular fractions prepared from islets of Langerhans. 5. The
      cyclic-AMP-dependent phosphorylation of histone had a K(m) for ATP of 1.1x10(
      5)m. 6. The endogenous protein phosphokinase activity in rat islets incubated
      with agents that are known to alter the intracellular concentration of cyclic AMP
      was investigated. Theophylline and 3-isobutyl-1-methylxanthine, agents that raise
      cyclic AMP concentrations in islets, increased the activity of the protein
      phosphokinase, whereas adrenaline, which lowers islet cyclic AMP concentrations,
      decreased its activity. 7. It is suggested that cyclic AMP may exert its effects
      on insulin release by increasing the activity of a protein phosphokinase and may
      thereby promote the phosphorylation and activity of a rate-determining component
      of the secretory mechanism.

PMID- 4349112
TI  - The primary structure of cytochrome c from the rust fungus Ustilago sphaerogena.
AB  - 1. The complete amino acid sequence of cytochrome c from the basidiomycete
      Ustilago sphaerogena was determined from the amino acid compositions and
      sequences of either tryptic or chymotryptic peptides, and in homology with at
      least thirty other established sequences of cytochrome c. 2. The primary
      structure of the molecule bears all of the characteristics of a mammalian-type
      cytochrome c, showing the typical clustered distribution of hydrophobic and basic
      residues with a single polypeptide chain of 107 residues. 3. Like all other
      fungal cytochromes c, it possesses a free N-terminus, and one less residue at the
      C-terminus than vertebrate cytochromes c. The region of residues 70-80 is
      strictly conserved, as is histidine at position 18. Position 26 is occupied by an
      asparagine residue, in contrast to histidine which occurs at this location in
      most of the known sequences of mammalian-type cytochromes c. 4. In contrast to
      some other fungal and plant cytochromes c of known primary structures, the
      Ustilago cytochrome c molecule does not contain trimethyl-lysine. 5. The sequence
      of Ustilago cytochrome c differs from the sequences of human, horse, chicken,
      tuna, wheat, and baker's yeast proteins at loci 47, 43, 44, 44 and 38
      respectively.

PMID- 4349113
TI  - The metabolism of cyclopentanol by Pseudomonas N.C.I.B. 9872.
AB  - 1. Pseudomonas N.C.I.B. 9872 grown on cyclopentanol as carbon source oxidized it
      at a rate of 228mul of O(2)/h per mg dry wt. and the overall consumption of
      5.9mumol of O(2)/mumol of substrate. Cyclopentanone was oxidized at a similar
      rate with the overall consumption of 5.2mumol of O(2)mumol of substrate. Cells
      grown with sodium acetate as sole source of carbon were incapable of significant
      immediate oxidation of these two substrates. 2. Disrupted cells catalysed the
      oxidation of cyclopentanol to cyclopentanone by the action of an NAD(+)-linked
      dehydrogenase with an alkaline pH optimum. 3. A cyclopentanolinduced
      cyclopentanone oxygenase (specific activity 0.11mumol of NADPH oxidized/min per
      mg of protein) catalysed the consumption of 1mumol of NADPH and 0.9mumol of O(2)
      in the presence of 1mumol of cyclopentanone. NADPH oxidation did not occur under
      anaerobic conditions. The only detectable reaction product with 100000g
      supernatant was 5-hydroxyvalerate. 4. Extracts of cyclopentanol-grown cells
      contained a lactone hydrolase (specific activity 7.0mumol hydrolysed/min per mg
      of protein) that converted 5-valerolactone into 5-hydroxyvalerate. 5.
      Cyclopentanone oxygenase fractions obtained from a DEAE-cellulose column were
      almost devoid of 5-valerolactone hydrolase and catalysed the formation of 5
      valerolactone in high yield from cyclopentanone in the presence of NADPH. 6.
      Incubation of 5-hydroxyvalerate with the 100000g supernatant, NAD(+) and NADP(+)
      under aerobic conditions resulted in the consumption of O(2) and the conversion
      of 5-hydroxyvalerate into glutarate. 7. The high activity of isocitrate lyase in
      cyclopentanol-grown cells suggests that the further oxidation of glutarate
      proceeds through as yet uncharacterized reactions to acetyl-CoA. 8. The reaction
      sequence for the oxidation of cyclopentanol by Pseudomonas N.C.I.B. 9872 is:
      cyclopentanol --> cyclopentanone --> 5-valerolactone --> 5-hydroxyvalerate -->
      glutarate --> --> acetyl-CoA.

PMID- 4349115
TI  - Complete amino acid analysis of peptides and proteins after hydrolysis by a
      mixture of sepharose-bound peptidases.
AB  - Incubation with a mixture of Sepharose-bound peptidases was shown to result in
      the quantitative release of amino acids from certain peptides and S
      aminoethylated proteins. Subtraction of the low background values of amino acids
      generated by the enzymes enables amino acid ratios of corticotrophin-(1-24)
      tetracosapeptide to be determined with a standard deviation on repeat digestions
      of 3-5%. Good values were obtained for amino acids that are completely or
      partially destroyed on acid hydrolysis, i.e. tryptophan, tyrosine, serine,
      asparagine and glutamine. Experiments with peptides containing d-amino acids
      showed that the enzyme mixture is stereospecific and could therefore be used to
      detect the presence of d-residues in peptides. The enzyme mixture completely
      hydrolyses peptide fragments obtained after Edman degradation and should
      therefore be useful for determining sequences of peptides containing acid-labile
      amino acid residues. The activities of the bound enzymes were unaltered over a
      period of 7 months and they provide a simple, reproducible procedure for the
      quantitative determination of amino acids in peptides and proteins containing l
      amino acids.

PMID- 4349114
TI  - The acid and enzymic hydrolysis of O-acetylated sialic acid residues from rabbit
      Tamm-Horsfall glycoprotein.
AB  - Rabbit Tamm-Horsfall glycoprotein and bovine submaxillary glycoprotein were both
      found to contain sialic acid residues which are released at a slow rate by the
      standard conditions of acid hydrolysis. These residues are also resistant to
      neuraminidases from Vibrio cholerae and Clostridium perfringens. This behaviour
      was attributed to the presence of O-acetylated sialic acid, since the removal of
      O-acetyl groups by mild alkaline treatment normalized the subsequent release of
      sialic acid from rabbit Tamm-Horsfall glycoprotein by acid and by enzymic
      hydrolysis. Determination of the O-acetyl residues in rabbit Tamm-Horsfall
      glycoprotein indicated that on average two hydroxyl groups of sialic acid are O
      acetylated, and these were located on the polyhydroxy side-chain of sialic acid
      or on C-4 and C-8. These findings confirm the assumption that certain O
      acetylated forms of sialic acid are not substrates for bacterial neuraminidases.
      Several explanations have been suggested to explain the effect of O-acetylation
      of the side-chain on the rate of acidcatalysed hydrolysis of sialic acid
      residues.

PMID- 4349116
TI  - A study of the phosphate linkages in phosphomannan in cell walls of Saccharomyces
      cerevisiae.
AB  - 1. The phosphomannan of Saccharomyces cerevisiae was released by Pronase
      digestion of cell walls and isolated by chromatography on DEAE-cellulose or by
      precipitation with borate-Cetavlon solutions. Mannose and phosphorus were present
      in the molar ratio 18:1 and the phosphate groups were in the diester form. 2.
      Hydrolysis with acid gave mannose 6-phosphate. Under mild acid conditions
      (autohydrolysis) the phosphate groups were converted into the monoester form,
      mannose was released and the molecular size of the phosphomannan was
      substantially decreased. 3. Hydrolysis with alkali also gave a monoester
      phosphate and a similar decrease in molecular weight. Under mild alkaline
      conditions the serine and threonine content of the phosphomannan was decreased by
      about 80%. The phosphate content was not altered. 4. Treatment with 40% (v/v) HF
      removed 70% of the phosphorus from the phosphomannan with no detectable decrease
      in molecular weight. 5. Periodate oxidation gave an oxophosphomannan from which
      80% of the phosphorus was eliminated under mild alkaline conditions. 6. The
      properties of the phosphomannan are consistent with a structure in which the
      phosphate groups are located on the outside of the molecule and link C-1 of a
      terminal mannose unit with C-6 of another mannose unit, which is in turn attached
      to the polysaccharide backbone of the molecule. 7. The implications of this
      structure are discussed in relation to flocculation.

PMID- 4349117
TI  - The binding of ribosomal subunits to endoplasmic reticulum membranes.
AB  - The binding of ribosomes and ribosomal subunits to endoplasmic reticulum
      preparations of mouse liver was studied. (1) Membranes prepared from rough
      endoplasmic reticulum by preincubation with 0.5m-KCl and puromycin bound 60-80%
      of added 60S subunits and 10-15% of added 40S subunits. Membranes prepared with
      pyrophosphate and citrate showed less clear specificity for 60S subunits
      particularly when assayed at low ionic strengths. (2) Ribosomal 40S subunits
      bound efficiently to membranes only in the presence of 60S subunits. The
      reconstituted membrane-60S subunit-40S subunit complex was active in synthesis of
      peptide bonds. (3) No differences in binding to membranes were seen between
      subunits derived from free and from membrane-bound ribosomes. (4) It is concluded
      that the binding of ribosomes to membranes does not require that they be
      translating a messenger RNA, and that the mechanism whereby bound and free
      ribosomes synthesize different groups of proteins does not depend on two groups
      of ribosomes that differ in their ability to bind to endoplasmic reticulum.

PMID- 4349118
TI  - The oxidation of nicotinic acid by Pseudomonas ovalis Chester. The terminal
      oxidase.
AB  - In cell-free extracts of Pseudomonas ovalis nicotinic acid oxidase is confined to
      the wallmembrane fraction. It is associated with an electron-transport chain
      comprising b- and c-type cytochromes only, differing proportions of which are
      reduced by nicotinate and NADH. CO difference-spectra show two CO-binding
      pigments, cytochrome o (absorption maximum at 417nm) and another component
      absorbing maximally at 425nm. Cytochrome o is not reduced by NADH or by succinate
      but is by nicotinate, which can also reduce the ;425' CO-binding pigment. The
      effects of inhibitors of terminal oxidation support the idea of two terminal
      oxidases and a scheme involving the ;425' CO-binding pigment and the other
      components of the electron-transport chain is proposed.

PMID- 4349119
TI  - A comparative study of the molecular structures of the plasma membranes and the
      smooth and the rough endoplasmic-reticulum membranes from rat liver.
AB  - Plasma-membrane as well as smooth-, rough- and degranulated-endoplasmic-reticulum
      membrane fractions were isolated from the microsomal pellet of rat liver. The
      purity of these fractions, as determined by marker-enzyme activities, electron
      microscopy, cholesterol content and RNA content, was found to be adequate for a
      comparative structural study. Major differences in lipid and protein composition
      were found to exist between the plasma membrane and the endoplasmic reticulum,
      but not between the smooth and the rough fractions of the endoplasmic reticulum.
      Differences in the location of membrane protein thiol groups and the mobility of
      the membrane phospholipids were observed between the plasma membranes and the
      endoplasmic reticulum, and these could be explained by differences in protein and
      lipid composition. However, by employing fluorescence and spin-labelling
      techniques structural changes were also observed between the smooth and the rough
      endoplasmic-reticulum fractions. These results suggest that the structural
      heterogeneity existing between the two latter membrane fractions occurs near or
      on their membrane surfaces and is not due to the greater number of ribosomes
      bound to the rough endoplasmic-reticulum fraction.

PMID- 4349120
TI  - [Regulation of the renin-angiotensin system].

PMID- 4349121
TI  - Theophylline compounds and myasthenia gravis. II. Clinical report of nine cases.

PMID- 4349123
TI  - Effects of cryogenic blocking of pulvinar upon visually evoked responses in the
      cortex of the cat.

PMID- 4349122
TI  - Actions of glutamic acid on spinal neurones.

PMID- 4349124
TI  - Neuronal hyperactivity following deafferentation of the lateral cuneate nucleus.

PMID- 4349125
TI  - [Trophoblastic disorders in Istael].

PMID- 4349126
TI  - [Clinical pathological study of granulosatheca cell tumor].

PMID- 4349127
TI  - [The feminizing ovarian tumor].

PMID- 4349128
TI  - [A comparison between cell-lines transformed by DNA tumor viruses and lysogenic
      bacteria].

PMID- 4349129
TI  - Retardation of peripheral nerve myelination in mice treated with inhibitors of
      cholesterol biosynthesis. A quantitative electron microscopic study.
AB  - The effect of two inhibitors of cholesterol biosynthesis, triparanol and AY 9944,
      on peripheral nerve myelination, was studied. Suckling mice were
      intraperitoneally injected with both drugs on 3 consecutive days and were
      sacrificed 6 hr after the last injection; others were suckled by an injected
      mother and sacrificed at 2(1/2) days of age. A single mouse which had been
      injected with both drugs at 1, 2, and 3 days of age was sacrificed 2 wk after the
      last injection. Membranous and crystalline intracytoplasmic inclusions were
      observed in the Schwann cells of the sciatic nerves of all the experimental
      animals. Both the number of unmyelinated single axons and the number of myelin
      lamellae around each myelinating axon in the sciatic nerves were recorded for
      treated mice and of mice suckled by treated mothers. The sciatic nerve of the
      experimental mice contained a larger proportion of unmyelinated single axons and
      smaller numbers of myelin lamellae around the myelinating axons, when compared
      with age-matched controls. The results suggest that a decrease of endogenous
      cholesterol in suckling mice may affect peripheral nerve myelination in two ways:
      by retarding the "triggering" of myelination in unmyelinated axons and by
      decreasing the rate of myelination already in progress.

PMID- 4349130
TI  - The intrarenal distribution of tritiated para-aminohippuric acid determined by a
      modified technique of section freeze-dry radioautography.
AB  - Section freeze-dry radioautography has been used to examine the intrarenal
      distribution of a water-soluble organic acid (para-aminohippuric acid (PAH-3H))
      under constant-infusion, steady-state conditions in mouse and rat kidney in vivo.
      The technique described here has the following advantages: (a) Sectioning and
      freeze-drying are accomplished in a closed cryostat at temperatures below -40
      degrees C; (b) Handling of the section is facilitated by mounting of the section
      to-be on adhesive-coated Saran Wrap prior to cutting; (c) Unembedded freeze-dried
      sections are attached to photographic film at ambient temperature in the dark
      room; (d) Fixation follows completion of radioautographic exposure and precedes
      photographic development; (e) Permanent close contact is maintained between
      tissue and film. Morphologic preservation compared favorably with that obtained
      by optimal fixation techniques, which, however, permit diffusion. Cellular
      accumulation of PAH-3H during secretion was demonstrated in the proximal tubule
      under steady-state conditions in vivo. The cellular concentration of PAH-3H was
      uniform throughout the length of the proximal tubule in mouse and rat kidney.

PMID- 4349131
TI  - Basal body replication and cilogenesis in a suctorian, Tokophrya infusionum.
AB  - Basal body replication and ciliogenesis in Tokophrya infusionum were studied in
      synchronized cultures. Basal body replication occurs during the 1st hr of
      reproduction, which in Tokophrya is by internal budding. The number of basal
      bodies increases from about 20 to over 300 within this period. New basal bodies
      develop in association with mature basal bodies; they are formed at right angles
      to the mature basal body as short "probasal" bodies, which elongate, slant
      upward, become parallel to the mature basal body, and elongate to the mature
      size. Ciliogenesis occurs only during reproduction; the nonreproducing adult is
      not ciliated, and has only 18-25 barren basal bodies. Cilia first appear as short
      bulges above the basal body. The axonemal structure is incomplete at first, with
      one or both central microtubules absent, and occasionally the B fibers of the
      outer doublets are missing. Several accessory fibers are associated with the
      basal bodies, both in the adult and during reproduction. One of the fibers
      appears only after the cilia have sprouted. The scheme of basal body replication
      and ciliogenesis in Tokophrya is compared to that reported in other organisms,
      and the role of the accessory fibers is discussed.

PMID- 4349133
TI  - Nuclear and organelle RNA synthesis in ochromonas: the effects of light.

PMID- 4349132
TI  - A new method for the preparation of rat liver lysosomes. Separation of cell
      organelles of rat liver by carrier-free continuous electrophoresis.
AB  - A combination of differential centrifugation and carrier-free continuous
      electrophoresis is introduced as a new method for the isolation of animal cell
      organelles. Various buffers were systematically checked in order to find the
      system which preserves the organelles and gives as well a good separation in the
      free-flow electrophoresis apparatus. Triethanolamine-acetate buffer (10 mM), pH
      7.4 was used. The isolated lysosomes were pure according to marker enzymes and
      electron micrographs. A heterogeneity of the lysosomes in electrophoretic
      mobility was demonstrated with respect to the marker enzymes arylsulfatase and
      beta-glucuronidase. The lysosomes with higher mobility showed a maximum
      enrichment of 240-fold with respect to arylsulfatase. The lysosomes with lower
      electrophoretic mobility showed a 65-fold enrichment with respect to beta
      glucuronidase. The ratio of beta-glucuronidase to arylsulfatase varied from 2:1
      to 1:2 in lysosomes of different mobility. The yield amounted to approximately 1
      mg of lysosomal protein per gram of liver protein. 5-8 mg of lysosomes can be
      obtained in one experiment. The electrophoretic separation proves to be an
      effective tool in obtaining pure and well preserved lysosomes.

PMID- 4349135
TI  - Patterns of cytomegaloviral complement-fixing antibody activity: a longitudinal
      study of blood donors.

PMID- 4349134
TI  - Photooxidation of diaminobenzidine (DAB) by chloroplast lamellae.

PMID- 4349136
TI  - The relationship between insulin secretion and triglyceride concentration in
      endogenous lipemia.

PMID- 4349137
TI  - Complement as a mediator of inflammation in acute gouty arthritis. I. Studies on
      the reaction between human serum complement and sodium urate crystals.

PMID- 4349138
TI  - The use of polyacrylamide gel electrophoresis in differentiating type 3
      hyperlipoproteinemia.

PMID- 4349139
TI  - Some practical innovations in the biological assay of adrenocorticotropic hormone
      (ACTH).

PMID- 4349140
TI  - [Abdominal tumors in childhood].

PMID- 4349141
TI  - [Circumoperative and postoperative cytostatic therapy in neuroblastomas and Wilms
      tumors in childhood].

PMID- 4349142
TI  - [Use of tissue extracts in the treatment of cancer].

PMID- 4349143
TI  - [Pathogenetic considerations on the etiology of cancer].

PMID- 4349145
TI  - [Radiological diagnosis of hormonally active tumors. Radiologic report].

PMID- 4349146
TI  - [Hormonally active tumors. Surgical report].

PMID- 4349144
TI  - [Hormone-active tumors].

PMID- 4349149
TI  - Participation of macrophages in tumor immunity.

PMID- 4349148
TI  - Relationship between blocking and unblocking activity and tumor growth in vivo.

PMID- 4349150
TI  - Augmented immunogenicity of tumor cell homogenates produced by infection with
      influenza virus.

PMID- 4349147
TI  - [Organ transplantation. With special reference to the liver].

PMID- 4349151
TI  - Introduction: diagnosis and immunotherapy of cancer.

PMID- 4349152
TI  - Histopathology of Mycobacterium bovis (BCG)-mediated tumor regression.

PMID- 4349153
TI  - Alpha-1-fetoprotein: serologic marker of human hepatoma and embryonal carcinoma.

PMID- 4349154
TI  - In vitro methods for assessment of antibody-mediated tumor immunity.

PMID- 4349155
TI  - Relationship between catecholamines and ACTH: effects of 6-hydroxy-dopamine.

PMID- 4349156
TI  - Determination of the nucleotide sequence of a fragment of bacteriophage phiX 174
      DNA.

PMID- 4349157
TI  - Influence of adeno-associated satellite virus on adenovirus-induced tumours in
      hamsters.

PMID- 4349158
TI  - Supercoiling of SV40 DNA can occur independently of replication.

PMID- 4349159
TI  - Occurrence of aminoacyl-tRNA synthetase in an RNA oncogenic virus.

PMID- 4349160
TI  - [Neurophysiologic methods in psychopharmacology].

PMID- 4349161
TI  - Studies on endoneoplastic transformation of glial tumors in vitro in long-term
      tissue cultures and subcultures.

PMID- 4349163
TI  - [Value of lymphography as complemetary examination in the diagnosis of
      rectosigmoideal cancer].

PMID- 4349164
TI  - Carcinoma of the pancreas.

PMID- 4349165
TI  - Glomus jugalare tumors: review and report of two cases.

PMID- 4349162
TI  - Laboratory evaluation of hypertension: renal mechanisms.

PMID- 4349166
TI  - The clinical laboratory in the investigation of patients with head injury.

PMID- 4349167
TI  - Effects of a week of ACTH or corticosteroid treatment on the diuretic response to
      water intake. A probably neuropostpituitary response to corticosteroid load.

PMID- 4349168
TI  - [Ultrastructural studies on changes in the synaptic structure and perikaryon of
      the central nervous system in the guinea pig (Cavia porcellus L.) during oxygen
      deficiency].

PMID- 4349169
TI  - On the fine structure of free nerve endings in human digital skin, oral cavity
      and rectum.

PMID- 4349170
TI  - Lysosomal structures in the stratum corneum of the ruminal epithelium of the
      sheep.

PMID- 4349171
TI  - Studies on the trophoblastic nidation of the mouse ovum.

PMID- 4349172
TI  - Platelets in the cytoplasm of adrenocortical cells injured by temporary ischemia.

PMID- 4349173
TI  - Hydrosmotic effect of angiotensin II: isolated toad bladder.

PMID- 4349174
TI  - Effects of ACTH and salt on blood pressure and steroid secretion in rats.

PMID- 4349176
TI  - Renal gluconeogenesis and mitochondrial NAD+-NADH ratios in nursing and adult
      rats.

PMID- 4349177
TI  - Mechanism of action of antiotensin II and antidiuretic hormone on renin
      secretion.

PMID- 4349175
TI  - Constrictor activity of angiotensins I and II on perfused vascular circuits of
      the dog.

PMID- 4349178
TI  - Effects of altitude stress on mitochondrial function.

PMID- 4349179
TI  - Renin-angiotensin system in primitive bony fishes and a holocephalian.

PMID- 4349181
TI  - Cavitating pulmonary metastatic disease in children.

PMID- 4349180
TI  - The roentgenographic manifestations of pulmonary opportunistic infections.

PMID- 4349182
TI  - Improved cryostat for spectrophotometry of cytochromes.

PMID- 4349183
TI  - Immobilized enzymes: a prototype apparatus for oxidase enzymes in chemical
      analysis utilizing covalently bound glucose oxidase.

PMID- 4349184
TI  - Human leukocyte interferon produced by use of an antibody-free human serum
      fraction.
AB  - An antibody-free human serum fraction has been prepared by ammonium sulfate
      precipitation. This fraction can be substituted for whole serum in the production
      of optimal yields of interferon by induced human leukocytes.

PMID- 4349186
TI  - Procedure for drying leptospiral antibody on sand and sugar for serological
      studies in leptospirosis.
AB  - A simple technique is described for drying sera on washed, dry sand or ordinary
      sugar cubes for the sero-diagnosis of leptospirosis. The results are shown to be
      very similar to those obtained with fluid sera or sera dried on filter paper
      discs. Sera adsorbed on sand or absorbed in sugar eliminated some of the problems
      associated with sera dried on paper. This method is suitable for use in the field
      and is expected to be of value in epizootiological studies where contamination
      and chemical denaturation of fluid serum samples held without refrigeration is a
      problem.

PMID- 4349185
TI  - Production and purification of large amounts of Rous sarcoma virus.
AB  - Procedures are described for production and purification of large amounts of Rous
      sarcoma virus. The virus was produced by Rous sarcoma virus-transformed chicken
      embryo fibroblasts in roller culture which produced up to 6 mg of virus per day
      per liter of supernatant fluid. Various methods of concentrating virus were
      evaluated; pelleting yielded the best results in terms of recovery of infectious
      virus. Purification was achieved by means of successive velocity and equilibrium
      density centrifugation by using sucrose solutions made in low-salt buffer. A
      rapid method for the optical density measurement of virus concentration was also
      developed.

PMID- 4349187
TI  - Method for detecting mycoplasma and bacterial L-form colonies in relief with an
      ordinary light microscope by means of oblique light.
AB  - A simple method is described for obtaining images in relief of fresh preparations
      with an ordinary light microscope by lowering the condenser and displacing the
      objective at an "off-clicked" position.

PMID- 4349188
TI  - [Histocompatibility antigens and trophoblastic tumors].

PMID- 4349189
TI  - [Basal plate of the mature human placenta. 3. Connective tissue and decidua
      cells].

PMID- 4349190
TI  - Sleep-wakefulness, EEG and behavioral studies of chronic cats without neocortex
      and striatum: the 'diencephalic' cat.

PMID- 4349191
TI  - Sleep-wakefulness, EEG and behavioral studies of chronic cats without the
      thalamus: the 'athalamic' cat.

PMID- 4349193
TI  - [Cosmic roentgen rays].

PMID- 4349192
TI  - [Immunobiology of cancer].

PMID- 4349194
TI  - [Value of retrograde pancreato-cholangiography in clinical diagnosis].

PMID- 4349195
TI  - [Normal and pathological emptying of the pancreatic duct, particularly in the
      presence of papillary stenosis].

PMID- 4349196
TI  - [Lipiodol ultra fluid hepatography, a critical evaluation].

PMID- 4349197
TI  - [Percutaneous transhepatic cholangiography. Recent experiences and findings].

PMID- 4349198
TI  - [Peritoneography with urovison before the introduction of radio-active gold].

PMID- 4349199
TI  - [Technic of hypotonic double contrast duodenography without duodenal intubation].

PMID- 4349200
TI  - [Radiological diagnosis of lactase deficiency].

PMID- 4349201
TI  - [Radiological and clinical features of intussusception].

PMID- 4349202
TI  - [Upper oesophageal varices due to thyroid enlargement].

PMID- 4349203
TI  - [Radiographic findings in the globus syndrome. I. Conventional radiographic
      examination of the esophagus and stomach, with the additional use of acid
      barium].

PMID- 4349205
TI  - [Morphology of mastopathy and mammary calcification in the radiographic
      examination of the breast].

PMID- 4349204
TI  - [Coeliac compression syndrome. A contribution on its etiology].

PMID- 4349206
TI  - [Puncture biopsy for mammary carcinoma].

PMID- 4349207
TI  - [Origin of an artery supplying the vertebral region, descending from the cervical
      sector of the right internal carotid artery].

PMID- 4349208
TI  - [Accidental thoracic myelography using Dimer X].

PMID- 4349209
TI  - [Post-traumatic pneumoencephalography].

PMID- 4349210
TI  - A theoretical model of the cerebral cortex.

PMID- 4349211
TI  - The interdependence series matrix; a method for determining the serial dependence
      of neuronal interspike intervals.

PMID- 4349212
TI  - On the transduction of visual, mechanical, and chemical stimuli.

PMID- 4349213
TI  - Action of ATP on the neural tissue-limb deplant of the salamander.

PMID- 4349214
TI  - Activity of enzymes related to neurotransmission in neuronal and glial fractions.

PMID- 4349215
TI  - Radiation damage to proteins--an e.s.r. study of a single crystal of glycyl
      glycine at low temperatures.

PMID- 4349216
TI  - Formation and trapping of radical pairs in irradiated thymine.

PMID- 4349217
TI  - E.p.r. of free radicals formed in DNA and its constituents after exposure to
      discharge-excited inert gases. I. Thymine and thymidine.

PMID- 4349218
TI  - [Free radicals induced by radiolysis of frozen solutions of thymidine-5'
      monophosphate].

PMID- 4349219
TI  - Diagnosis of upper and mid inferior vena caval obstruction.

PMID- 4349220
TI  - Ultrastructural localization of phospholipid synthesis in the rat trigeminal
      nerve during myelination.
AB  - A method for the ultrastructural localization of acyltransferase enzymes involved
      in phospholipid metabolism has been applied to the developing rat trigeminal
      nerve. Determination of acyltransferase levels in the nerve indicated that a peak
      of activity occurs at the 8th day after birth with gradual declines of activity
      up to 15 days. Morphological surveys and determinations of cholesterol levels
      suggested that heavy myelin formation occurs in the nerve during this latter
      period. Fixed nerves incubated in a medium for localization of acyltransferases
      indicated deposition of reaction product associated with Golgi cisternae,
      intracellular smooth vesicles, and the plasma membrane of the Schwann cell in the
      incipient stages of myelin formation. Golgi-derived vesicles appeared to move
      toward the Schwann cell surface and fuse with the plasma membrane. Activity
      continued to be detectable in the plasma membrane of the internal mesaxon as long
      as cytoplasm was evident and mature myelin membrane was not yet formed. Cells in
      which myelin formation appeared advanced showed little or no enzyme marker.
      Consistent with cytochemical observations were biochemical determinations of
      acyltransferases which showed high levels of the enzymes in microsomes, while no
      activity could be detected in the myelin fraction. Acyltransferase reaction
      product was also observed in the Golgi apparatus of ganglion cell bodies,
      axoplasmic smooth vesicles, and the axolemma. Localization of acyltransferase
      enzymes in Schwann cells, ganglion cell bodies, and axons during development of
      the nerve is discussed in relation to membrane biogenesis in the nervous system.

PMID- 4349221
TI  - Localization of Na + , K + -ATPase and other enzymes in teleost pseudobranch. I.
      Biochemical characterization of subcellular fractions.
AB  - In an effort to determine the subcellular localization of sodium- and potassium
      activated adenosine triphosphatase (Na(+), K(+)-ATPase) in the pseudobranch of
      the pinfish Lagodon rhomboides, this tissue was fractionated by differential
      centrifugation and the activities of several marker enzymes in the fractions were
      measured. Cytochrome c oxidase was found primarily in the mitochondrial-light
      mitochondrial (M+L) fraction. Phosphoglucomutase appeared almost exclusively in
      the soluble (S) fraction. Monoamine oxidase was concentrated in the nuclear (N)
      fraction, with a significant amount also in the microsomal (P) fraction but
      little in M+L or S. Na(+), K(+)-ATPase and ouabain insensitive Mg(2+)-ATPase were
      distributed in N, M+L, and P, the former having its highest specific activity in
      P and the latter in M+L. Rate sedimentation analysis of the M+L fraction
      indicated that cytochrome c oxidase and Mg(2+)-ATPase were associated with a
      rapidly sedimenting particle population (presumably mitochondria), while Na(+),
      K(+)-ATPase was found primarily in a slowly sedimenting component. At least 75%
      of the Na(+), K(+)-ATPase in M+L appeared to be associated with structures
      containing no Mg(2+)-ATPase. Kinetic properties of the two ATPases were studied
      in the P fraction and were typical of these enzymes in other tissues. Na(+), K(+)
      ATPase activity was highly dependent on the ratio of Na(+) and K(+)
      concentrations but independent of absolute concentrations over at least a
      fourfold range.

PMID- 4349222
TI  - Two actions of cyclic AMP on melanosome movement in frog skin. Dissection by
      cytochalasin B.
AB  - Photomicrography and reflectance microphotometry were used to monitor melanosome
      movement in frog skin melanocytes in vitro in response to hormonal stimulation
      and cytochalasin B (CB). Melanocyte-stimulating hormone (MSH), theophylline, and
      dibutyryl cyclic AMP (DiBcAMP) induced melanosome dispersion (darkening) which
      was promptly arrested by cytochalasin B in concentrations of 5-20 microg/ml.
      Melanosome aggregation (skin lightening) occurred only after removal of the
      darkening agent (MSH, theophylline, or DiBcAMP) and proceeded in the presence or
      absence of CB. When CB was added to darkened skins, they did not lighten and
      melanosomes remained in the dispersed state. Use of CB has permitted the
      dissection of cyclic AMP-mediated melanosome dispersion into two distinct events.
      The first, induction of melanosome dispersion, is CB sensitive. The second action
      of intracellular cyclic AMP involves an uncoupling of the centripetal motive
      force, and is CB insensitive. In the latter process, production of cyclic AMP
      appears to produce the same result as application of microtubule-disrupting
      agents.

PMID- 4349223
TI  - Retinal structure in the smooth dogfish, Mustelus canis: light microscopy of
      photoreceptor and horizontal cells.

PMID- 4349224
TI  - The responses of the sebaceous glands of the hypophysectomized-castrated male rat
      to 5 -androstanedione and 5 -androstane-3 ,17 -diol.

PMID- 4349225
TI  - Chemotherapy of cutaneous herpesvirus infection of hairless mice.

PMID- 4349226
TI  - Congenital adrenal hypoplasia: an isolated defect of organogenesis.

PMID- 4349227
TI  - Detection of heterozygous carriers of the Lesch-Nyhan syndrome by electrophoresis
      of hair root lysates.

PMID- 4349228
TI  - A Y-autosome translocation 46,X,t(Yq-7q+) associated with multiple congenital
      anomalies.

PMID- 4349229
TI  - Antidiuretic therapy in Bartter's syndrome.

PMID- 4349230
TI  - Familial glucocorticoid insufficiency.

PMID- 4349231
TI  - Tracheostomy in primary herpetic gingivostomatitis.

PMID- 4349232
TI  - Poland's syndrome associated with leukemia.

PMID- 4349233
TI  - [After-treatment of alcoholics in the department of Vienna in France].

PMID- 4349234
TI  - [COFAL Test. 2. Demonstration of group specific antigens in avian sarcoma and
      leukosis viruses using chick embryo fibroblast tissue culture].

PMID- 4349235
TI  - Reactions between an insect picornavirus and naturally occurring IgM antibodies
      in several mammalian species.

PMID- 4349236
TI  - Vascular permeability factor: dissociation from the angiotensin II induced
      pressor and drinking responses.

PMID- 4349237
TI  - Cyclic AMP does not affect the rate at which cells attach to a substratum.

PMID- 4349238
TI  - Comparison of the redox assay for ACTH with previous assays.

PMID- 4349239
TI  - Nitrofurantoin polyneuropathy.

PMID- 4349240
TI  - On the state of the nervous system.

PMID- 4349241
TI  - [Total plasma angiotensinase activity in essential hypertension].

PMID- 4349242
TI  - The effect of ACTH administration on plasma testosterone, dihydrotestosterone and
      serum LH concentrations in normal men.

PMID- 4349243
TI  - [Allergic dermatitis following 2,4-dinitrochlorbenzol in childhood leukemia and
      solid tumors].

PMID- 4349244
TI  - [Malignant tumors of the upper respiratory tracts in the Tunisian Republic from
      1965 to 1969].

PMID- 4349245
TI  - [Hypereosinophilia of the blood and eosinophilia of the C.S.F. accompanying the
      development of cerebral glioblastoma].

PMID- 4349246
TI  - Regulation of staphylococcal enterotoxin B: effect of anaerobic shock.
AB  - The metabolism of glucose during enterotoxin B synthesis in Staphylococcus aureus
      S-6 was examined under anaerobic conditions in the presence and absence of
      nitrate. The repression of enterotoxin synthesis which occurs during the
      oxidative metabolism of glucose was relieved after a shift to anaerobic
      conditions; glucose was then converted primarily to lactic acid and was
      metabolized more rapidly, presumably to obtain the equivalent amount of energy
      available aerobically. A greater proportion of oxidized end products and
      evidently more energy per glucose molecule was produced in the presence of
      oxygen. Thus, available energy as judged by a change in the type and proportion
      of end products appears to be related to the degree of toxin repression. As
      expected, the addition of nitrate during anaerobic glucose metabolism prevented
      derepression of toxin synthesis.

PMID- 4349247
TI  - Comparison of direct and indirect solid-phase microradioimmunoassays for the
      detection of viral antigens and antiviral antibody.
AB  - Viral antigens were fixed to the surface of microtiter wells, and serial
      dilutions of antiviral antibody were added. The amount of antiviral antibody
      bound to viral antigens was determined by measuring the extent to which the
      antiviral antibody either inhibited the specific binding of (125)I-labeled
      antiviral immunoglobulin G (IgG) (direct technique) or enhanced the specific
      binding of (125)I-labeled anti-IgG (indirect technique). Immune complexes
      composed of viral antigens and antiviral antibody (human) could be detected by
      the binding of (125)I-labeled rheumatoid factor. Specific binding was influenced
      by the concentration of protein in the diluents used during the different steps
      of the procedure. A high concentration of protein in the diluent used with the
      viral antigens decreased specific binding, whereas a high concentration of
      protein in the diluent used with (125)I-labeled anti-IgG increased specific
      binding by decreasing nonspecific attachment of the labeled anti-IgG. Under the
      conditions employed, the titer of a given antiviral serum was several hundredfold
      greater by the indirect than by the direct technique.

PMID- 4349248
TI  - Quantitative assessment of hemadsorption by myxoviruses: virus hemadsorption
      assay.
AB  - The standardization and quantitative evaluation of an assay for myxoviruses,
      based on the enumeration of individual infected clone 1-5C-4 cells manifesting
      hemadsorption within 24 h of infection, are described. Hemadsorption was
      detectable earlier than immunofluorescence in infected cells or hemagglutinins in
      culture medium. The relationship between virus concentration and cells exhibiting
      hemadsorption was linear. The assay was highly precise, sensitive, and
      reproducible.

PMID- 4349249
TI  - Quantitative assessment of hemadsorption by myxoviruses: anti-immunoglobulin G
      hemadsorption-inhibition test.
AB  - A quantitative hemadsorption-inhibition test was developed to estimate myxovirus
      serum antibodies within 24 h by determining the serum dilution inhibiting
      hemadsorption in 50% of the infected cells. The test depends on the interactions
      of virus-infected cell monolayers with antiviral serum and of the resultant
      complexes with antiimmunoglobulin G serum. The incorporation of species-specific
      anti-immunoglobulin G serum into the test significantly increased sensitivity.

PMID- 4349250
TI  - Flocculant and chemical properties of a polysaccharide from Pullularia pullulans.
AB  - An extracellular polysaccharide, PP-floc, was synthesized from glucose by
      Pullularia pullulans (or Aureobasidium pullulans) in a pilot plant batch
      fermentor containing 175 liters of culture medium. At 58 h of fermentation, the
      concentration of PP-floc was 1.03 g/100 ml, giving a 25.8% conversion of initial
      glucose to polysaccharide. The flocculant activity of the culture medium
      increased during the fermentation process and reached its maximum at 50 h of
      culture age. Less PP-floc (0.33 lb/ton of slimes [approximately 149.7 g/0.907 t])
      was required to give the same flocculant activity as a synthetic polymer of
      acrylamide, Separan NP-10 (0.5 lb/ton of slimes [approximately 226.8 g/0.907 t]),
      at all temperatures from 25 to 100 C. The degree of inactivation of PP-floc and
      Separan NP-10 at elevated temperatures was almost identical, and they were
      completely inactivated at about the same temperature (80 C). PP-floc also gave
      better compaction of slimes than Separan NP-10 at all temperatures tested. PP
      floc was soluble in water and its specific optical rotation was [alpha](D) (25) +
      194 degrees in water (c, 0.4). PP-floc contained 83.3% carbohydrate, 3.2%
      protein, and 8.1% water. Glucose was found to be the principal sugar monomer with
      traces (>5%) of galactose and mannose present. Structural studies on the
      fractions of purified polysaccharide by methylation and by periodate oxidation
      techniques prove that PP-floc is linear and composed of alpha-(1 --> 4) and alpha
      (1 --> 6) glucopyranosyl units in the approximate ratio of 2:1. The action of
      pullulanase on crude PP-floc suggested the ordered arrangement of two consecutive
      alpha-(1 --> 4)-linked glucopyranosyl units flanked by alpha-(1 --> 6)-linked
      glucopyranose residues.

PMID- 4349251
TI  - Experience with an image-analyzing computer in virus plaque measurements.
AB  - Due to the extremely fast and reliable plaque-number determinations, the image
      analyzing computer is most useful for large screening programs involving plaque
      reduction tests.

PMID- 4349252
TI  - Fish viruses: buffers and methods for plaquing eight agents under normal
      atmosphere.
AB  - A universal procedure was sought for plaque assay of eight fish viruses (bluegill
      myxovirus, channel catfish virus, eel virus, Egtved virus, infectious
      hematopoietic necrosis virus, infectious pancreatic necrosis virus, lymphocystis
      virus, and the agent of spring viremia of carp (Rhabdovirus carpio), in dish
      cultures of various fish cells. Eagle minimal essential medium with sodium
      bicarbonate-CO(2) buffer (Earle's salt solution) was compared with minimal
      essential medium buffered principally with tris (hydroxymethyl)aminomethane or N
      2-hydroxyethylpiperazine-N'-2'-ethanesulfonic acid at a pH or in the range of 7.6
      to 8.0 depending upon temperature. Five fish cell lines collectively capable of
      replicating all fish viruses thus far isolated were tested and quantitatively
      found to grow comparably well in the three media. Two-phase (gel-liquid) media
      incorporating the various buffer systems allowed plaquing at 15 to 33 C either in
      partial pressures of CO(2) or in normal atmosphere, but greater efficiency and
      sensitivity were obtained with the organic buffers, and, overall, the best
      results were obtained with tris(hydroxymethyl)aminomethane. Epizootiological
      data, specific fish cell line response, and plaque morphology permit presumptive
      identification of most of the agents. At proper pH, use of organic buffers
      obviates the need for CO(2) incubators.

PMID- 4349253
TI  - Nuclear magnetic resonance studies of alcohol dehydrogenases. Binding of
      inhibitors to the yeast and liver enzymes.

PMID- 4349254
TI  - Interaction of chloride ion with horse liver alcohol dehydrogenase-reduced
      nicotinamide adenine dinucleotide complexes.

PMID- 4349256
TI  - In vitro adenylylation of lysine-sensitive aspartylkinase from Escherichia coli
      TIR-8.

PMID- 4349255
TI  - Simultaneous binding of competitive ligands to horse liver alcohol dehydrogenase.

PMID- 4349257
TI  - Spectroscopic and magnetic studies of iron (3) phosvitins.

PMID- 4349258
TI  - A complex of cytochrome c and mixed mitochondrial phospholipids.

PMID- 4349261
TI  - The purification of lysosomes from HeLa cells by centrifugation in colloidal
      silica density gradients.

PMID- 4349260
TI  - Rapid two-channel microfluorimetry: a method for comparative study of metabolism,
      phase differences or transport in the cytoplasm and nucleus.

PMID- 4349262
TI  - Magnetic properties of potassium dithioferrate: a linear chain antiferromagnet
      and model compound for the exchange interactions in two-iron ferredoxins.

PMID- 4349259
TI  - Cofactor activity of protein components of human very low density lipoproteins in
      the hydrolysis of triglycerides by lipoproteins lipase from different sources.

PMID- 4349263
TI  - On the mechanism of superoxide dismutase. Reaction of the bovine enzyme with
      hydrogen peroxide and ferrocyanide.

PMID- 4349264
TI  - The reaction of nitric oxide with ceruloplasmin.

PMID- 4349265
TI  - Adenosine 3',5'-monophosphate-dependent protein kinase of bovine tracheal smooth
      muscle.

PMID- 4349266
TI  - The phytases. II. Properties of phytase fractions F 1  and F 2  from wheat bran
      and the myoinositol phosphates produced by fraction F 2 .

PMID- 4349268
TI  - Cerebral metabolic effects of hyperventilation and deliberate hypotension.

PMID- 4349267
TI  - The metabolic and endocrine response to injury: a review.

PMID- 4349269
TI  - Effects of anaesthetic agents on metabolic pathways: fuel utilization and supply
      during anaesthesia.

PMID- 4349270
TI  - Endocrine responses to anaesthetic agents.

PMID- 4349271
TI  - [Steroid diagnosis of adrenal cortex disorders. IV. Factors influencing the
      quality of examination].

PMID- 4349272
TI  - Indirect inhibition of the biosynthesis of 1,25-dihydroxycholecalciferol in rats
      treated with a diphosphonate.

PMID- 4349274
TI  - Two sites of cardiovascular action of angiotensin II in the brain of the dog.

PMID- 4349273
TI  - Plasma volume, extracellular fluid volume and exchangeable sodium concentrations
      in the New Zealand strain of genetically hypertensive rat.

PMID- 4349275
TI  - A preliminary attempt to measure continuity of care in a community mental health
      center.

PMID- 4349276
TI  - Evaluation of chronic pain in children.

PMID- 4349277
TI  - The pathophysiology of pain.

PMID- 4349278
TI  - [Clinical evaluation of Peridontone ointment for topical treatment of oral mucosa
      erosions and small ulcerations].

PMID- 4349279
TI  - Problems of information processing in the nervous system.

PMID- 4349280
TI  - Transfer of information within the cockroach central nervous system during shock
      avoidance learning: is there a nerve impulse code(s) for learned information?

PMID- 4349281
TI  - Medical schools and teaching hospitals should become involved in development and
      operation of PSROs.

PMID- 4349282
TI  - An electrophysiological investigation of skeletal muscle in Parkinson's disease.

PMID- 4349283
TI  - Ultrastructure of a human spinal neuroma.

PMID- 4349284
TI  - Amyloidosis.

PMID- 4349285
TI  - Gout.

PMID- 4349286
TI  - Chondrocalcinosis and pseudogout.

PMID- 4349287
TI  - Primary neoplasms of joints.

PMID- 4349288
TI  - Mechanism of the enzymatic reaction catalyzed by UDPG dehydrogenase. I. Study of
      the initial rate and kinetic mechanism of the reaction.

PMID- 4349290
TI  - Investigation of conformational transitions of cytochrome c by the spin-tag
      method.

PMID- 4349289
TI  - Investigation of electrostatic charges in proteins by the paramagnetic probe
      method.

PMID- 4349291
TI  - Modification of E. coli B RNA-polymerase by 2,2,6,6-tetramethyl-4
      chloromercuricarbobenzoxypiperidine-1-oxyl.

PMID- 4349292
TI  - The secondary structure of collagenase.

PMID- 4349293
TI  - Single fibre EMG in juvenile myasthenia gravis.

PMID- 4349294
TI  - The relationship between maternal and neonatal sleep.

PMID- 4349295
TI  - Eye movements in infants using DC recording.

PMID- 4349296
TI  - Involvement of sural nerve in neuronal ceroid-lipofuscinoses: report of two
      cases.

PMID- 4349297
TI  - Papaverine antagonism of prostaglandin E 2 -induced contraction of rabbit aortic
      strips.

PMID- 4349298
TI  - Sex-dependent effects of cyclic AMP on the hepatic mixed function oxidase system.

PMID- 4349299
TI  - Effect of theophylline on alkaline phosphatase activity of denervated skeletal
      muscle fibers.

PMID- 4349300
TI  - [Cycl AMP and function of the hypothalamo-hypophyseal thyroid system].

PMID- 4349301
TI  - [A case of biliary cirrhosis of the liver caused by metastasis of hormono-active
      arrhenoblastoma into hepatic duct].

PMID- 4349302
TI  - [Changes in blood cholinesterase activity in cerebrovascular disorders].

PMID- 4349303
TI  - [Dopaminergic conception of Parkinsonism and its treatment with L-DOPA].

PMID- 4349304
TI  - Inclusion bodies in cells from a hydatidiform mole.

PMID- 4349305
TI  - Intranuclear cytoplasmic inclusions in some types of thyroid cancer.

PMID- 4349306
TI  - Cytology of diffuse liver disorders.

PMID- 4349307
TI  - Cytologic changes of the respiratory tract in young adults as a consequence of
      high levels of air pollution exposure.

PMID- 4349308
TI  - Bronchial brushing technique for the cytologic diagnosis of peripheral lung
      lesions. A review of 693 cases.

PMID- 4349310
TI  - [Immunodynamics of lupus erythematodes].

PMID- 4349311
TI  - Cyclic AMP.

PMID- 4349309
TI  - Cytologic detection of vaginal parasitosis.

PMID- 4349313
TI  - Rural emergency psychiatric services.

PMID- 4349312
TI  - Collagenase debridement.

PMID- 4349315
TI  - Immunohistochemical and histochemical studies of pituitary beta-lipotrophs.

PMID- 4349314
TI  - Are stages of sleep related to waking behavior?

PMID- 4349317
TI  - A Novel function of cytochrome C (555, Chlorobium thiosulfatophilum) in oxidation
      of thiosulfate.

PMID- 4349316
TI  - Cytochrome oxidase and NADH cytochrome c. Reductase distribution during skin
      wound healing in rats of various ages.

PMID- 4349318
TI  - Diadenosine tetraphosphate splitting by rat liver extracts.

PMID- 4349319
TI  - An alternate enzymic route for the synthesis of the alkyl analog of phosphatidic
      acid involving alkylglycerol.

PMID- 4349320
TI  - Clustering of lecithin molecules in phosphatidylserine membranes induced by
      calcium ion binding to phosphatidylserine.

PMID- 4349321
TI  - On the structure of NADH-X.

PMID- 4349322
TI  - The effect of starvation on tissue adenosine 3'-5' monophosphate levels.

PMID- 4349323
TI  - Incorporation in vitro of purified cytochrome b 5  into liver microsomal
      membranes.

PMID- 4349324
TI  - Ribonuclease H activity present in purified DNA polymerase from avian
      myeloblastosis virus.

PMID- 4349325
TI  - Reversible inactivation by NADH and ADP on Chlorella fusca nitrate reductase.

PMID- 4349326
TI  - Fluorescence studies of a cytochrome C mixed phospholipid complex.

PMID- 4349327
TI  - Heme modification studies of myoglobin. I. Purification and some optical and EPR
      characteristics of synthesized myoglobins containing unnatural hemes.

PMID- 4349328
TI  - Kinetics and equilbria among the multiple forms of ferricytochrome.

PMID- 4349329
TI  - The effect of the sialyl residues on the thermodynamic and hydrodynamic
      properties of   1 -acid glycoprotein.

PMID- 4349330
TI  - A rat-specific lysine-rich histone.

PMID- 4349331
TI  - Alkaline sucrose sedimentation studies of DNA from P388F lymphoma cells treated
      with disfunctional alkylating agents.

PMID- 4349332
TI  - Differences in the transfer RNA methyltransferases from normal rat liver and
      Novikoff hepatoma.

PMID- 4349333
TI  - Structural analyses of mammalian ribosomal ribonucleic acid and its precursors.
      The distribution of polypyrimidine sequences in ribosomal 18-S RNA.

PMID- 4349334
TI  - Value of an ACTH test in assessing hypothalamic-pituitary-adrenocortical function
      in glucocorticoid-treated patients.
AB  - Forty-eight patients receiving glucocorticoid treatment were tested with ACTH
      stimulation using alpha(1, 24) ACTH (tetracosactrin). All patients subsequently
      underwent non-acute major surgery without any glucocorticoid administration, and
      their clinical course and plasma corticosteroids were followed closely. No case
      of adrenocortical insufficiency was observed. A highly significant correlation
      was found between the pre-operative adrenocortical response to ACTH and the
      hypothalmic-pituitary-adrenocortical (H.P.A.) response to surgery. A normal
      response to ACTH stimulation was never followed by a greatly impaired H.P.A.
      response to surgery. It seems that a simple ACTH stimulation test is reliable in
      predicting the integrated H.P.A. response to major stress in glucocorticoid
      treated patients.

PMID- 4349335
TI  - Persistence of tanapox in Tana River valley.
AB  - Sera collected from inhabitants of the Tana River valley in 1971 were examined
      for antibody to tanapox virus. Neutralizing antibody was present in 16.3%. The
      levels of antibody and its presence in two children under the age of 10 years
      indicated that infection had been occurring in the area since the reported
      outbreak in 1962. A comparison of the incidence and distribution of antibodies in
      the same sera to West Nile virus revealed marked similarities suggesting that
      tanapox, like West Nile virus infections, might be transmitted in the same way
      namely, by a culicine mosquito.

PMID- 4349336
TI  - Outbreak in Bristol of conjunctivitis caused by adenovirus type 8, and its
      epidemiology and control.
AB  - In an investigation of an outbreak of adenovirus type 8 infection involving over
      40 people it was found that the infection spread initially within the eye
      hospital, but subsequently involved several family contacts and two local
      hospitals for mentally subnormal patients. Presumptive diagnosis should be
      possible before subepithelial opacities have developed provided an adequate
      history is taken, and had that been done in this outbreak it is reasonable to
      suppose that many cases could have been prevented.

PMID- 4349337
TI  - Enterovirus infections.

PMID- 4349338
TI  - Zollinger-Ellison syndrome reclassified.

PMID- 4349339
TI  - A spin probe study of the influence of cholesterol on motion and orientation of
      phospholipids in oriented multibilayers and vesicles.

PMID- 4349340
TI  - Effects of intravenous neuraminidase on the turnover of fibrinogen.

PMID- 4349341
TI  - Studies with a mass balance method of measuring fibrinogen synthesis.

PMID- 4349342
TI  - Future developments in prophylaxis.

PMID- 4349343
TI  - Intrauterine infections: chairman's summary.

PMID- 4349344
TI  - Congenital cytomegalovirus infections.

PMID- 4349345
TI  - Foetal interferon responses induced by rubella virus.

PMID- 4349346
TI  - Serum lipoprotein patterns in patients with coronary atherosclerosis.

PMID- 4349347
TI  - Choice of conditions for the gradient flotation of serum lipoproteins in swing
      out rotors.

PMID- 4349348
TI  - Pathological effects of lead.

PMID- 4349350
TI  - Ultrastructural alterations in X-irradiated epidermis.

PMID- 4349349
TI  - The role of renal factors in the pathogenesis of experimental hypertension.

PMID- 4349351
TI  - An ultrastructural study of embryonal rhabdomyosarcoma (Sarcoma botryoides) of
      the bladder.

PMID- 4349352
TI  - Studies on the neutralization of herpes simplex virus. VI. The mode of action of
      complement upon antibodysensitized virus.

PMID- 4349354
TI  - Plaque formation by herpes simplex virus in established calf kidney cells.

PMID- 4349353
TI  - Origin of thymidine kinase in the cells infected with infectious canine hepatitis
      virus.

PMID- 4349355
TI  - Adenovirus infection in intussusception of Japanese infants.

PMID- 4349356
TI  - Narcolepsy.

PMID- 4349357
TI  - Stimulation by cyclic AMP and ppGpp of chloramphenicol acetyl transferase
      synthesis.

PMID- 4349358
TI  - Phospholipid incorporation into plasma membrane of lactating mammary cell with
      special reference to sphingomyelin.

PMID- 4349359
TI  - Australian tiger snake venom--an inhibitor of transmitter release.

PMID- 4349360
TI  - Effect of lysine vasopressin and ACTH 4-10  on conditioned avoidance behavior of
      hypophysectomized rats.

PMID- 4349361
TI  - Effect of stress and hypothalamic deafferentation on the secretion of growth
      hormone in the rat.

PMID- 4349362
TI  - Evidence for a diurnal fluctuation in plasma corticosterone levels after fornix
      transection in the rat.

PMID- 4349363
TI  - Basal-cell adenoma of the upper lip. Report of a case.

PMID- 4349364
TI  - Malignant fibrous histiocytoma of the soft tissues of the mandible.

PMID- 4349365
TI  - [Functional and histochemical studies of the liver in hemorrhagic shock and in
      posthemorrhagic states].

PMID- 4349366
TI  - [Kinetic methods of determination of serum enzymatic activity].

PMID- 4349367
TI  - Metabolism of ethanol and its effects upon the liver.

PMID- 4349368
TI  - Electron spin resonance and pulse radiolysis studies of irradiated aqueous
      solutions of 5-nitrouracils. Oxidative denitration by OH radicals.

PMID- 4349369
TI  - [Hemolytic anemia associated with hepatocarcinoma].

PMID- 4349370
TI  - [Sympathetic participation in the regulation of the adrenal cortex].

PMID- 4349371
TI  - Endocrine liver tumours.

PMID- 4349372
TI  - Carcinoma in a Hamman-Rich lung. A case report.

PMID- 4349373
TI  - Angiotensin, aldosterone and DOC in hypertensive disease of pregnancy.

PMID- 4349375
TI  - [Renovascular hypertension: conditions of superiority of surgical treatment and
      their effects on various diagnostic investigations].

PMID- 4349374
TI  - [Hemolytic anemia induced by penicillin during agranulocytosis with plasmocytic
      reaction of the bone marrow. Apropos of a case. Review of the literature].

PMID- 4349377
TI  - [Thoracic pains. Rhomboideus "pedicle" syndrome].

PMID- 4349376
TI  - [Paraneoplastic syndrome with multiple manifestations revealing hypernephroma
      with presence of alpha-feto-protein].

PMID- 4349378
TI  - "Fingerprint inclusions" in muscle fibres in dystrophia myotonica.

PMID- 4349379
TI  - Mechanism of demyelination in JHM virus encephalomyelitis. Electron microscopic
      studies.

PMID- 4349380
TI  - A piezoelectric cascade impactor for aerosol monitoring.

PMID- 4349381
TI  - The digestion of lung tissue for mineral dust recovery.

PMID- 4349383
TI  - Spontaneous regression of a putative childhood hepatoma. A reappraisal.

PMID- 4349382
TI  - Growth in children following renal transplantation.

PMID- 4349384
TI  - An alternative in trophoblastic disease follow-up.

PMID- 4349385
TI  - Taurodont, pyramidal and fused molar roots associated with other anomalies in a
      kindred.

PMID- 4349386
TI  - Growth and skeletal maturation in British Columbia Indian Populations.

PMID- 4349387
TI  - Carpal tunnel syndrome in rheumatoid arthritis.

PMID- 4349388
TI  - Primary malignant tumors of the esophagus other than typical epidermoid
      carcinoma.

PMID- 4349389
TI  - [Several aspects of the predentin role in the differentiation of ameloblasts].

PMID- 4349390
TI  - Biological activity of 2-phenylethanol and its derivatives. 8. Influence on
      herpesvirus DNA-synthesis in rabbit kidney cells.

PMID- 4349391
TI  - In situ fragmentation of RNA in poliovirus.

PMID- 4349392
TI  - Thermosensitive events in adenovirus transformed cells. I. Resistance to herpes
      simplex virus.

PMID- 4349393
TI  - Thermosensitive events in adenovirus transformed cells. II. Helping of adenovirus
      associated viruses.

PMID- 4349394
TI  - Effect of phleomycin on the replication of mengovirus in novikoff hepatoma cells.

PMID- 4349395
TI  - Interferon induction by rice dwarf virus RNA. Antiviral activity in vitro and its
      stability.

PMID- 4349396
TI  - DEAE-dextran enhancement of in vivo infection with murine leukemia virus.

PMID- 4349397
TI  - Ultrastructural study on the sequence of human cytomegalovirus infection in human
      diploid cells.

PMID- 4349398
TI  - [Cellular origin or rabbit serum interferon induced by Newcastle disease virus].

PMID- 4349400
TI  - Lyophilization of varicella virus. Brief report.

PMID- 4349399
TI  - Experimental corneal infection of the cebus monkey with herpesvirus hominis type
      1 and type 2.

PMID- 4349401
TI  - Hypertension with adrenal, genital, renal defects, and deafness. A new familial
      syndrome.

PMID- 4349403
TI  - Glomus jugulare tumour: a case report.

PMID- 4349402
TI  - The substitution of corticotrophin for corticosteroid in the treatment of
      children and adults with chronic asthma.

PMID- 4349405
TI  - Kinetics of refolding of guanidine hydrochloride denatured cytochrome c.
      Temperature dependence.

PMID- 4349404
TI  - Monkeypox virus.

PMID- 4349406
TI  - Synthesis, biological activity, and  19 F nuclear magnetic resonance spectra of
      angiotensin II analogs containing fluorine.

PMID- 4349407
TI  - Measurement of fast lateral diffusion of lipids in vesicles and in biological
      membranes by  1 H nuclear magnetic resonance.

PMID- 4349409
TI  - Effects of catecholamines on ammoniagenesis and gluconeogenesis by renal cortex
      in vitro.

PMID- 4349410
TI  - Preovulatory changes in the synthesis of cyclic AMP by rabbit Graafian follicles.

PMID- 4349408
TI  - Stimulation of renal gluconeogenesis by inhibition of the sodium pump.

PMID- 4349411
TI  - Structural studies on avian myeloblastosis virus: conditions for isolation and
      biochemical characteristics of the core component.

PMID- 4349412
TI  - Hormone- and fluoride-sensitive adenylate cyclases in human fetal tissues.

PMID- 4349413
TI  - Studies on a peptidase acting on a synthetic collagenase substrate. Developmental
      pattern in rat granuloma tissue and distribution of enzyme in the tissues of
      various animals.

PMID- 4349414
TI  - Two anti-anxiety drugs: a psychoneuroendocrine study.
AB  - Eight males were studied during 27 weeks, including two periods of five weeks
      during which they received clinical doses of sodium amylobarbitone and
      benzoctamine. Substitution of placebo for either drug caused raised anxiety and
      impairment of mental concentration. The drugs reduced restlessness during sleep
      and reduced paradoxical sleep. By the fifth week of sodium amylobarbitone,
      although sleep was still less restless in the early night it was more restless
      than normal in the late night.Blood samples were taken half-hourly during sleep
      by indwelling venous catheter. Plasma growth hormone concentration was little
      affected during drug administration but rose temporarily after withdrawal. There
      was a reduction of plasma corticosteroid concentration during sleep throughout
      administration of the drugs and a rebound above normal during the first
      withdrawal week.

PMID- 4349415
TI  - Acute respiratory virus infections.

PMID- 4349416
TI  - Clarke's column and the dorsal spinocerebellar tract: a review.

PMID- 4349417
TI  - [Treatment of extensive 3d degree burns].

PMID- 4349418
TI  - Critical periods in brain development. In: lipids, malnutrition & the developing
      brain.

PMID- 4349419
TI  - The phylogenetic evolution of the corneal stroma. Distribution of carbohydrates
      in the macromolecular complexes of the primate baboon (Cynocephalus papio-papio)
      corneal stroma.

PMID- 4349420
TI  - Studies on enzymes from parasitic helminths. 3. Purification and properties of
      lactate dehydrogenase from the tapeworm, Hymenolepis diminuta.

PMID- 4349421
TI  - Temperature-sensitive mutations in Drosophila melanogaster. XII. The genetic and
      developmental effects of dominant lethals on chromosome 3.
AB  - Out of 25,000 EMS-treated third chromosomes examined, ten dominant temperature
      sensitive (DTS) lethal mutations which are lethal when heterozygous at 29 degrees
      C but survive at 22 degrees C were recovered. Seven of the eight mutations mapped
      were tested for complementation; these mutants probably define eight loci. Only
      DTS-2 survived in homozygous condition at 22 degrees C; homozygous DTS-2 females
      expressed a maternal effect on embryonic viability. Two of the mutant-bearing
      chromosomes, DTS-1 and DTS-6, exhibited dominant phenotypes similar to those
      associated with Minutes. Each of the seven mutants examined exhibited a
      characteristic phenotype with respect to the time of death at 29 degrees C and
      the temperature-sensitive period during development. Only DTS-4 exhibited
      dominant lethality in triploid females.

PMID- 4349422
TI  - Methadone in a 30-day detoxification program for narcotic addicts: a critical
      review.

PMID- 4349423
TI  - Action in primary afferent fibers in the spinal cord.

PMID- 4349424
TI  - A mode control model of a neuron's axon and dendrites.

PMID- 4349425
TI  - Excitability changes during the sleep cycle in the cat.

PMID- 4349426
TI  - A model of hippocampal CA3 circuitry.

PMID- 4349428
TI  - Energy and signal.

PMID- 4349427
TI  - Synaptic inhibition in the spinal cord.

PMID- 4349429
TI  - Integration in the nervous system: the starch for its mechanisms.

PMID- 4349430
TI  - Effects of the electrophoretic application of sulfhydryl reagents to the end
      plate receptors.

PMID- 4349431
TI  - Statistical analysis of sleep in rats.

PMID- 4349432
TI  - Radiologic manifestations of mongolism.

PMID- 4349433
TI  - [Psychotherapy for schizophrenic patients within the framework of hospital social
      psychiatry].

PMID- 4349434
TI  - Induction of polyoma virus by fluorescent (visible) light in polyoma-transformed
      cells pretreated with 5-bromodeoxyuridine.

PMID- 4349435
TI  - Genetic control of the group-specific antigen of murine leukaemia virus.

PMID- 4349436
TI  - Binding of N-acetyl-neuraminic acid by wheat-germ agglutinin.

PMID- 4349437
TI  - Ribonucleoprotein binding of steroid-"receptor" complexes.

PMID- 4349438
TI  - Control of phenotypic expression of cultured melanoma cells by melanocyte
      stimulating hormones.

PMID- 4349439
TI  - Chronic stress effects on adrenocortical responsiveness in young and aged rats.

PMID- 4349441
TI  - Control of staphylococcal infections and disease in the newborn through the use
      of hexachlorophene bathing.

PMID- 4349442
TI  - [Recurrent Abrikosov's myoblastic myoma of the female breast].

PMID- 4349440
TI  - Amino acids and polypeptides in neuronal function.

PMID- 4349443
TI  - [Ectopic hormonal syndromes].

PMID- 4349444
TI  - [Addison's disease followed-up for 11 years. Comatose episodes, development of
      polyendocrine diseases. Pathogenetic and therapeutic considerations].

PMID- 4349445
TI  - [Sheehan's disease followed by severe arterial hypertension with right renal
      artery stenosis. Discussion of the role of hypopituitarism in atherogenesis].

PMID- 4349446
TI  - [Long-term prognosis in treated Cushing's disease in the child. Apropos of a case
      followed-up for 10 years].

PMID- 4349447
TI  - [Clinical, hematological and virological aspects of cytomegalovirus diseases].

PMID- 4349448
TI  - [Some observations on amebiasis in the Armenian SSR].

PMID- 4349449
TI  - [Experience in using hysterosalpingography and hydrotubation for the diagnosis of
      sterility in ambulatory patients].

PMID- 4349450
TI  - Improved gel-filtration method for analysis of estrogen receptor binding.

PMID- 4349451
TI  - Continuous fractionation of proteins and mucopolysaccharides by simultaneous two
      dimensional gel filtration and electrophoresis.

PMID- 4349452
TI  - Problems in the measurement of bile acids with 3 -hydroxysteroid dehydrogenase.

PMID- 4349454
TI  - A simplified radiometric assay for plasma norepinephrine and epinephrine.

PMID- 4349455
TI  - A new, sensitive method for the determination of streptomycin.

PMID- 4349453
TI  - Separation and identification of Neurospora phosphatases by polyacrylamide gel
      electrophoresis.

PMID- 4349457
TI  - [Tumor of the pharyngeal extension of the parotid].

PMID- 4349456
TI  - [Association of cirrhosis and cancer. Contribution of laparoscopy and biopsy
      (apropos of 26 cases)].

PMID- 4349459
TI  - Interference with polyoma virus replication by homologous incomplete virus.

PMID- 4349458
TI  - [Results of radiotherapy of non-fixed vocal cord carcinomas: correlation with a
      classification].

PMID- 4349460
TI  - Cell surface antigen on quail cells infected with herpesvirus of turkey or
      Marek's disease virus.

PMID- 4349461
TI  - Photo-oxidative modification of the heme ligands in horse heart ferricytochrome
      c: conformational and functional studies.

PMID- 4349462
TI  - Activation of leucocyte collagenase proenzyme by rheumatoid synovial fluid.

PMID- 4349464
TI  - Actinomycin D for Wilm's tumour.

PMID- 4349463
TI  - Investigation of crosslinks in collagen following an enzymic hydrolysis.

PMID- 4349465
TI  - Hyperlipidaemia in asthmatic patients receiving long-term steroid therapy.
AB  - Plasma lipids were measured in 100 female asthmatic patients receiving long-term
      steroid therapy. A significant increase in the incidence of endogenous
      hypertriglyceridaemia but not of hypercholesterolaemia was found. The
      hypertriglyceridaemia was not due to obesity or diabetes. Neither the dose of
      steroid, duration of therapy, nor the addition of corticotrophin gel or depot
      tetracosactrin influenced the prevalence of hypertriglyceridaemia.

PMID- 4349466
TI  - Studies on the replication of polyoma DNA: physicochemical properties of viral
      DNA synthesized when protein synthesis is inhibited.

PMID- 4349467
TI  - The mechanism of a host-dependent abortive bacteriophage infection in
      Caulobacter.

PMID- 4349468
TI  - Antigenic homogeneity of enterotoxin from different agglutinating serotypes of
      Clostridium perfringens.

PMID- 4349469
TI  - A study of phagocytosis of radio-labeled Staphylococcus epidermidis and on
      structural events during intracellular degradation.

PMID- 4349470
TI  - Degradation of poliovirus RNA in vivo.

PMID- 4349471
TI  - Enhancement of interferon production of murine peritoneal leukocytes by mineral
      oil: the effect of experimental EMC infection in mice.

PMID- 4349472
TI  - Further studies on a glycolipid formed from dolichyl-D-glucosyl monophosphate.

PMID- 4349473
TI  - [Vaccination of a large cattle herd against infectious pustular vulvovaginitis
      and rhinotracheitis].

PMID- 4349474
TI  - [Demonstration of an ectromelia enzootic in hairless mice].

PMID- 4349475
TI  - [The effect of copper ions on the functional state of the neuromuscular
      apparatus].

PMID- 4349477
TI  - Sexual dimorphism in hand and wrist ossification.

PMID- 4349476
TI  - Stimulation of intestinal mucosal proliferation by vitamin D.

PMID- 4349478
TI  - Hexose transport in normal and in Rous sarcoma virus-transformed cells.

PMID- 4349479
TI  - On the role of heme in the formation of the structure of cytochrome c.

PMID- 4349480
TI  - Evidence for an androgen-independent mechanism regulating the levels of receptor
      in target tissue.

PMID- 4349481
TI  - Studies on the relationship between androgen receptors and the transport of
      androgens in rat prostate.

PMID- 4349482
TI  - Activation of a guanosine triphosphate-specific protein kinase by adenosine 3':5'
      monophosphate-dependent protein kinase in rat cells of the rat.

PMID- 4349483
TI  - Evidence for delayed development of the glucagon receptor of adenylate cyclase in
      the fetal and neonatal rat heart.
AB  - The effects, in vivo, of epinephrine, glucagon, and dibutyryl cyclic adenosine
      3',5'-monophosphate (cyclic AMP) on the glycogen content of rat heart and liver
      and, in vitro, upon adenylate cyclase activity in homogenates of rat heart and
      liver were determined during the latter third of gestation and the neonatal
      period. Hepatic glycogen was depleted by epinephrine, glucagon, and dibutyryl
      cyclic adenosine 3',5'-monophosphate, but myocardial glycogen was depleted only
      by epinephrine and dibutyryl cyclic AMP in the neonates. Hepatic adenylate
      cyclase activity was augmented by both epinephrine (10(-5) M) and glucagon (10(
      5) M), and myocardial cyclase was increased only by epinephrine in tissue
      obtained from 16, 18, and 20 day fetal rats. Myocardial adenylate cyclase
      responsiveness to glucagon was present in tissue obtained from rats 4 wk of age
      and older. It is concluded that in contrast to hepatic adenylate cyclase,
      myocardial adenylate cyclase in the rat is not responsive to glucagon during
      gestation and that responsiveness to glucagon and the associated ability of
      glucagon to deplete myocardial glycogen do not develop until well after birth.

PMID- 4349484
TI  - Plasma lipoproteins in familial lecithin: cholesterol acyltransferase deficiency.
      Further studies of very low and low density lipoprotein abnormalities.
AB  - Plasma lipoproteins of d<1.006 g/ml, d 1.006-1.019 g/ml, and d 1.019-1.063 g/ml
      from patients with familial lecithin:cholesterol acyltransferase deficiency
      yielded abnormal subfractions upon being separately filtered through 2% agarose
      gel. A subfraction that emerged with the void volume and contained unusually
      large amounts of unesterified cholesterol and phosphatidylcholine was present in
      each lipoprotein group, and in each group this subfraction was less prominent in
      the nonlipemic plasma of one patient than in the lipemic plasma of other
      patients. A subfraction containing smaller lipoproteins also was present in each
      lipoprotein group. These lipoproteins were of the same size as normal
      lipoproteins of the corresponding density, but contained abnormally small amounts
      of cholesteryl ester. The lipoproteins of 1.019-1.063 g/ml contained abnormal
      components of intermediate molecular weight as well as large and small abnormal
      components similar to those described previously. The intermediate components
      were more prominent in the nonlipemic plasma but were easily recognized in the
      hyperlipemic plasma as a peak of S(f) 20-30 in the analytical ultracentrifuge.
      Also they could be recognized, upon electron microscopy of the lipoproteins of d
      1.019-1.063 g/ml, as particles 340-1000 A in diameter. The data suggest that
      related large, abnormal particles pervade the patients' very low and low density
      lipoproteins, and that the large particles are affected by, but are not dependent
      on, the lipemia that frequently accompanies the disease. The smaller very low and
      low density lipoproteins appear to be counterparts of lipoproteins present in
      normal plasma. Their abnormal composition is compatible with the possibility that
      lecithin:cholesterol acyltransferase normally decreases the triglyceride and
      phosphatidylcholine and increases the cholesteryl ester of very low density and
      low density plasma lipoproteins in vivo.

PMID- 4349485
TI  - Specific biologic effects of intestinal glucagon-like materials.
AB  - It has been demonstrated that gastrointestinal extracts contain substances which
      react immunologically with antibodies prepared to pancreatic glucagon. These
      extracts have been termed intestinal GLI for glucagon-like immunoreactivity, or
      enteroglucagon. To determine whether GLI has specific biological effects, studies
      were designed using the criterion of effect with antiglucagon antibodies. These
      antibodies did not cross-react with either secretin or pancreozymin. Rat
      intestinal extracts were prepared and filtered on Sephadex G-50 columns eluted in
      0.02 M ammonium carbonate buffer pH 8.8. Two peaks of GLI (I, II) were
      consistently found, and the in vitro effects of these peaks on two biological
      systems were tested: (a) immunoreactive insulin (IRI) release by rat pancreas
      pieces, and (b) free fatty acid (FFA) release and 3',5'-cyclic adenosine
      monophosphate (cAMP) levels in adipose tissue. Both GLI peaks increased IRI
      release in the absence of glucose and also enhanced the glucose effects.
      Antiglucagon antibody suppressed only peak II GLI activity. Both peaks increased
      FFA release and cAMP levels in adipose tissue. Only peak II GLI activity was
      suppressed by antibody. These findings support a specific IRI-releasing and
      lipolytic action for Peak II GLI. Hypotheses are presented concerning the
      structure and possible physiologic role of peak II GLI.

PMID- 4349487
TI  - Study of the pedigree of a patient with type 3 hyperlipoproteinaemia and sinking
      prebeta lipoprotein.
AB  - A 49-year-old woman, suffering from peripheral vascular disease, was found to
      have two lipoprotein abnormalities, namely, type III hyperlipoproteinaemia and
      sinking prebeta lipoprotein. Twenty-one members of the kindred were investigated
      in an attempt to determine the pattern of inheritance of both of these
      abnormalities. In a 21-year-old son of the proband plasma electrophoresis was in
      keeping with a type V hyperlipoproteinaemia. It is suggested that this may be a
      stage in the development of the characteristic type III pattern. If this is so it
      is consistent with previous suggestions of an incompletely penetrant single
      autosomal allele. Sinking prebeta lipoprotein was found in the plasma of two
      other members of the family. If this abnormality is also inherited as a single
      autosomal allele it must have a very low penetrance and the possibility that the
      abnormality is acquired cannot be excluded.

PMID- 4349488
TI  - Simple economical anaerobiosis.

PMID- 4349486
TI  - Glucagon release induced by pancreatic nerve stimulation in the dog.
AB  - A direct neural role in the regulation of immunoreactive glucagon (IRG) secretion
      has been investigated during stimulation of mixed autonomic nerves to the
      pancreas in anesthetized dogs. The responses were evaluated by measurement of
      blood flow and hormone concentration in the venous effluent from the stimulated
      region of pancreas. Electrical stimulation of the distal end of the discrete
      bundles of nerve fibers isolated along the superior pancreaticoduodenal artery
      was invariably followed by an increase in IRG output. With 10-min periods of
      nerve stimulation, the integrated response showed that the higher the control
      glucagon output, the greater was the increment. Atropinization did not influence
      the response to stimulation. That the preparation behaved in physiologic fashion
      was confirmed by a fall in IRG output, and a rise in immunoreactive insulin (IRI)
      output, during hyperglycemia induced by intravenous glucose (0.1 g/kg). The
      kinetics of this glucose effect on IRG showed characteristics opposite to those
      of nerve stimulation: the lower the control output, the less the decrement.
      Furthermore, during the control steady state, blood glucose concentration was
      tightly correlated with the IRI/IRG molar output ratio, the function relating the
      two parameters being markedly nonlinear. Injection or primed infusion of glucose
      diminished the IRG response to simultaneous nerve stimulation. Measurement of IRG
      was inferred to reflect response of pancreatic glucagon secretion on the basis of
      the site of sample collection (the superior pancreaticoduodenal vein), the
      absence of changes in arterial IRG, and similar responses being obtained using an
      antibody specific for pancreatic glucagon. THESE STUDIES SUPPORT A ROLE FOR THE
      AUTONOMIC NERVOUS SYSTEM IN THE CONTROL OF GLUCAGON SECRETION: direct nerve
      stimulation induces glucagon release. Such sympathetic activation may be
      interpreted as capable of shifting the sensitivity of the A cell to glucose in
      the direction of higher glycemia for a given glucagon output. The experimental
      model employed is valid for further studies of regulatory mechanisms of endocrine
      pancreatic function in vivo.

PMID- 4349489
TI  - Inhibition of replication of lactic dehydrogenase virus by actinomycin.
AB  - Lactic dehydrogenase virus replicated rapidly in monolayers of primary mouse
      embryo cells and reached a titer of 10(8) mean infective dose per ml within 18 h
      after infection. Despite the high virus yield, cytopathology was not observed.
      Examination of the tissue culture media failed to reveal any evidence of
      interferon, but the virus was found to be as sensitive to mouse interferon as
      vesicular stomatitis virus. Incubation of mouse embryo cells with actinomycin D
      markedly inhibited viral replication, whereas cytosine-beta-d-arabinofuranoside
      and 5-fluorodeoxyuridine had no effect on replication. These findings indicate
      that new DNA synthesis is not required but suggest that the intact function of
      cellular DNA may be required for lactic dehydrogenase virus replication.

PMID- 4349490
TI  - Initiation and direction of RNA transcription by vesicular stomatitis virus
      virion transcriptase.
AB  - The initiation of RNA transcription by the virion-bound RNA transcriptase of
      vesicular stomatitis virus has been examined. Multiple initiation sequences have
      been observed, two of which have been characterized (pppApCpGp... and pppGpCp...)
      suggestive of a transcription process which can start at different sites along
      the template RNA. By the use of sequential labeling techniques and exonucleases,
      it has been determined that there is a 5' to 3' direction of product RNA
      synthesis.

PMID- 4349491
TI  - Analysis of simian virus 40 DNA with the restriction enzyme of Haemophilus
      aegyptius, endonuclease Z.
AB  - Limited digestion of simian virus 40 (SV40) DNA from both small- and large-
      plaque strains with the restriction endonuclease Z from Haemophilus aegyptius
      yielded 10 specific fragments. The number of nucleotide pairs for each fragment,
      determined by co-electrophoresis with phiX174 RF fragments produced by
      endonuclease Z, ranges from 2,050 to 80. The difference in the pattern between
      the large- and small-plaque strains is the disappearance of one fragment
      containing approximately 255 nucleotide pairs and the appearance of a new
      fragment with 145 nucleotide pairs. This finding can be explained either by
      deletions or insertions totaling 110 nucleotide pairs. Complementary RNA
      synthesized in vitro from the adeno-SV40 hybrid virus, strain ND-1, hybridized
      preferentially to four of the fragments of SV40 DNA.

PMID- 4349492
TI  - Surface antigens on cat leukemic cells induced by feline leukemia virus: area
      density and antibody-binding affinity.
AB  - The binding of autologous bovine antibody to feline leukemia virus-induced cell
      surface antigens (FeCSA) on cat leukemia cells was studied by performing certain
      titration procedures with a mixture of immune and normal sera labeled with
      different iodine radioisotopes (paired-label technique). By using plots of
      titration data which conformed to linear equations derived from the mass action
      law, we determined the following constants. (i) The density of FeCSA was 2.03 x
      10(6) sites per cell, or 5,230 sites per mum(2). (ii) The equilibrium constant of
      the FeCSA-antibody reaction was 2.67 x 10(7), from which the antibody binding
      affinity or standard free energy of the FeCSA-antibody bond was determined to be 
      10.48 kcal (-43,869.28 J) per mol. The use of the techniques described to
      measure the concentration of antibody in antiserum, in micrograms per milliliter,
      is discussed.

PMID- 4349493
TI  - Identification of the vesicular stomatitis virus large protein as a unique viral
      protein.
AB  - Previous studies have noted the existence of a 190,000-dalton vesicular
      stomatitis virus (VSV) protein called the large (L) protein. To determine whether
      this protein is a nonspecific aggregate, a precursor to the other VSV proteins,
      or a unique viral protein, its synthesis relative to the other VSV proteins was
      studied under conditions of inhibition of initiation of protein synthesis. Also,
      its tryptic peptides were compared to those of the other VSV proteins. In both
      cases the results were consistent with the identification of the large protein as
      a unique viral protein.

PMID- 4349494
TI  - Synthesis of type 2 adenovirus DNA in the presence of cycloheximide.
AB  - Adenovirus type 2 DNA synthesis, either in permissive human cells or
      nonpermissive monkey cells, becomes independent of protein synthesis after the
      appearance of progeny viral DNA. In the presence of cycloheximide,
      semiconservative replication and initiation of progeny molecules can occur.

PMID- 4349496
TI  - Intracytoplasmic A particles: mouse mammary tumor virus nucleoprotein cores?
AB  - A rapid method for the isolation of intracytoplasmic A particles, the putative
      intracellular nucleoprotein cores of mouse mammary tumor virus (MTV), is
      presented. Spontaneous C3H/He mouse mammary tumors and transplantable mouse
      Leydig cell tumor were used as source material. Large aggregations of
      intracytoplasmic A particles were separated from cellular contaminants on
      discontinuous sucrose gradients and subsequently further purified by isopycnic
      banding in linear sucrose gradients. The purified particles were solubilized in
      sodium dodecyl sulfate, and the structural proteins were analyzed by sodium
      dodecyl sulfate-polyacrylamide gel electrophoresis. Purified mouse mammary tumor
      virions were solubilized, and their proteins were analyzed in the same way.
      Comparison of co-electrophoretic gels indicated a lack of correlation in the
      molecular size of the major structural proteins in intracytoplasmic A particles
      and MTV. The three major proteins of the A particles were calculated to be
      80,000; 35,000; and 20,000 daltons. Five major polyacrylamide gel electrophoresis
      bands were obtained with purified MTV; these were 90,000; 69,000; 55,000; 37,000;
      and 27,500 daltons. These figures showed good correlation with those published
      for MTV by Nowinski et al. These results suggest the need for the reexamination
      of the current tenet that intracytoplasmic particles represent intracellular MTV
      nucleoprotein cores.

PMID- 4349497
TI  - Purification by oligo(dT)-cellulose of viral-specific RNA from sarcoma virus
      transformed mammalian nonproducer cells.
AB  - Viral-specific RNA has been purified by oligo(dT)-cellulose chromatography from
      sarcoma virus-transformed nonproducer cells. This RNA comprises approximately 3%
      of the purified RNA, as judged by RNA-DNA hybridization.

PMID- 4349495
TI  - New intermediate subviral particles in the in vitro uncoating of reovirus virions
      by chymotrypsin.
AB  - Reovirus virions, grown in suspension cultures of L cells and extensively
      purified by density gradient and velocity gradient centrifugation after their
      release from cell debris by fluorocarbon extraction, are characterized by a mean
      particle diameter of 73 nm and a density in CsCl of 1.36 to 1.37 g/cm(3).
      Treatment of intact virions by chymotrypsin (CHT) digestion in vitro converts
      them to subviral particles (SVP) having characteristics which are determined by
      the species of monovalent cation present during the digestion. In the presence of
      Cs(+) ions, CHT converts the virions to SVP of mean diameter 51 nm and density
      1.43 to 1.44 g/cm(3). In the presence of K(+) ions, the conversion is to SVP of
      diameter 51 nm and density 1.39 to 1.40 g/cm(3). The SVP made in the presence of
      either Cs(+) or K(+) possess an extremely active RNA polymerase and nucleoside
      triphosphate phosphohydrolase (NTPase) activity in vitro and are resistant to
      further digestion by CHT. Treatment of intact virions with CHT in the presence of
      Na(+) or Li(+) ions results in their conversion to SVP of mean diameter 64 nm and
      density 1.37 to 1.38 g/cm(3). Such SVP are not active in in vitro RNA synthesis
      or NTP hydrolysis and are resistant to further digestion by CHT even during
      prolonged exposure to high concentrations of enzyme. Addition of Cs(+) or K(+)
      ions to the digestion mixture allows conversion of the 64-nm diameter SVP to 51
      nm diameter SVP in which the RNA polymerase and NTPase are active in vitro.
      Analysis of the proteins present in intact virions and in the different SVP
      reveals clear differences which indicate that the conversions are accomplished by
      removal or cleavage of particular species of polypeptides.

PMID- 4349498
TI  - Effect of isotopic label on buoyant density determinations of viral DNA in the
      preparative ultracentrifuge.
AB  - The buoyant density of herpes simplex virus DNA may be significantly increased by
      isotopic labeling, particularly with (14)C. The apparent increase in buoyant
      density may be readily calculated from the specific activity of the DNA and is
      easily demonstrated by isopycnic centrifugation in both the preparative and
      analytical centrifuge.

PMID- 4349499
TI  - A genetic model of the host range restriction of murine leukemia viruses: a
      review and a hypothesis.

PMID- 4349500
TI  - Purification of commercially available fluorescein isothiocyanate by silicic acid
      column chromatography.

PMID- 4349501
TI  - Properties of a cytopathic agent isolated from a patient with subacute sclerosing
      panencephalitis in Japan.

PMID- 4349502
TI  - Effect of dibutyryl cyclic AMP on nucleic acid and protein synthesis in neuronal
      and glial tumor cells.

PMID- 4349503
TI  - [Dissemination of enteroviruses in human environment. II. Occurrence and survival
      of poliovirus in above-the-ground parts of vegetable plants grown on infected
      soil].

PMID- 4349504
TI  - Case records of the Massachusetts General Hospital. Weekly clinicopathological
      exercises. Case 23-1973.

PMID- 4349505
TI  - Trigeminal neuralgia and herpesvirus.

PMID- 4349506
TI  - Drug receptors and the haemopoietic stem cell.

PMID- 4349507
TI  - [Renin producing tumors].

PMID- 4349508
TI  - Hyaluronate inhibition of chondrogenesis: antagonism of thyroxine, growth
      hormone, and calcitonin.
AB  - The formation of cartilage-like aggregates in high-density stationary cultures of
      trypsinized chick embryo precartilage cells is blocked by low concentrations of
      hyaluronate. Thyroxine (and triiodothyronine), growth hormone, calcitonin, and
      adenosine 3',5'-monophosphate prevented this inhibition by hyaluronate, whereas
      other hormones tested did not.

PMID- 4349509
TI  - Cyclic AMP phosphodiesterase in cloned astrocytoma cells: norepinephrine induces
      a specific enzyme form.
AB  - The soluble supernatant fraction of homogenates of cloned rat astrocytoma cells
      (linle C-2A) was subjected to polyacrylamide gel electrophoresis. Two peaks of
      adenosine 3',5'-monophosphate phosphodiesterase activity were found,
      corresponding to peaks I and IV of a similarly prepared homogenate of rat brain.
      Incubating cells with norepinephrine (0.3 mullimolar) caused about a threefold
      increase in the activity of peak IV but no change in peak I. This increase was
      completely inhibited by prior inclubation with propranolol (0.1 millimnolar), a
      beta-adrenergic blocking agent, or with cyclohexamnine (40 micromolar). a protein
      synthesis inhibitor. Induction of a specific phosphodiesterase form by
      norepinephrine sitggests another feedback control mechanism whereby an organism
      can prevent the effects of excessive sympathetic activity.

PMID- 4349510
TI  - Octopamine-sensitive adenylate cyclse: evidence for a biological role of
      octopamine in nervous tissue.
AB  - An adenylate cyclase that is activated specifically by very low concentrations of
      octopamine has been identified both in homogenates and in intact cells of the
      thoracic ganglia of an insect nervous system. This enzyme appears to be distinct
      from two other adenylate cyclases present in the same tissue, which are activated
      by dopamine and by 5-hydroxytryptamine, respectively. The data raise the
      possibility of a role of octopamine-sensitive adenylate cyclase in the physiology
      of synaptic transmission.

PMID- 4349511
TI  - Leukemia virus activation during homograft rejection.
AB  - Activation of murine leukemia viruses, as detected by the mixed culture
      cytopathogenicity (XC) assay, followed the transplantation of A/J skin onto
      immunosuppressed BALB/c mice. Virus was found in most of the mice receiving both
      skin grafts and antilymphocyte serum, but not in animals receiving either the
      serum alone, skin graft alone, or no treatment.

PMID- 4349512
TI  - Genetic mapping of the Fv-1 lcous of the mouse.
AB  - The Fv-l locus of the mouse, a major determinant of the biology of murine
      leukemia virus, is very closely linked to Gpd-1 on chromosome 4 (linkage group
      VIII).

PMID- 4349513
TI  - [Recurrent jaundice in pregnancy and chronic isolated cholangiolitis or Hanot-Mac
      Mahon disease].

PMID- 4349514
TI  - [Fuso-cellular thymoma associated with erythroblastopenia, megakaryocytopenia and
      cytomegalic inclusion disease].

PMID- 4349515
TI  - [Functional clinical and infrastructural study of a case of primary elastosic
      pulmonary sclerosis].

PMID- 4349516
TI  - [Association of myeloma and hyperlipidemia with xanthomatous eruption].

PMID- 4349517
TI  - [Notched patella (a type of hyperostosis of ligament insertion)].

PMID- 4349518
TI  - [Tuberculous osteitis and osteo-arthritis in displaced black Africans. Apropos of
      50 cases].

PMID- 4349519
TI  - [Intra-arterial cholesterol crystals].

PMID- 4349520
TI  - [Doctor Tchekhov].

PMID- 4349521
TI  - [The morbid universe of Marcel Proust].

PMID- 4349522
TI  - [The medical dynasty of the Pelletans].

PMID- 4349523
TI  - [The functional state of the adrenal cortex in congenital heart defects of the
      pale type].

PMID- 4349525
TI  - [An automatic apparatus for the determination of kinetic parameters of enzymatic
      reactions].

PMID- 4349524
TI  - Cholesterol content and phospholipid composition of Morris hepatoma microsomes.

PMID- 4349526
TI  - [Treatment of epilepsy in children].

PMID- 4349528
TI  - Height and weight of United States children: second report.

PMID- 4349527
TI  - Gangliosidosis with total hexosaminidase deficiency: clinical, biochemical and
      ultrastructural studies and comparison with conventional cases of Tay-Sachs
      disease.

PMID- 4349529
TI  - Control of vasopressin stimulation of sodium transport in the toad bladder.

PMID- 4349530
TI  - Response of frog muscle spindle system to whole-muscle input parameters.

PMID- 4349531
TI  - Angiotensin I conversion in the kidney and its modulation by sodium balance.

PMID- 4349533
TI  - Extra-adrenal effect of ACTH on fibrinogen synthesis.

PMID- 4349532
TI  - Effects of parathyroid hormone on renal tubular reabsorption of calcium, sodium,
      and phosphate.

PMID- 4349534
TI  - Influence of hypophysectomy and training on size of isolated fat cells.

PMID- 4349535
TI  - Angiotensin, vasopressin, and cyclic AMP: effects on sodium and water fluxes in
      rat colon.

PMID- 4349536
TI  - GABA-transaminase inhibitors and presynaptic inhibition in the amphibian spinal
      cord.

PMID- 4349537
TI  - Research utilization, a problem in goal setting: what is the question?

PMID- 4349538
TI  - Premorbid adjustment, paranoid diagnosis, and remission. Acute schizophrenics
      treated in a community mental health center.

PMID- 4349539
TI  - [A case of primary bronchiolo-avleolar cancer].

PMID- 4349541
TI  - Electrical activity in neocortical projection and association areas during slow
      wave sleep.

PMID- 4349540
TI  - Production of histamine-like and prostaglandin-like substances from serum
      incubated with rat, dog, mouse or human tumours.

PMID- 4349542
TI  - [Identification of foot-and-mouth disease virus types].

PMID- 4349543
TI  - [Identification of foot-and-mouth disease virus types].

PMID- 4349544
TI  - The prevention and treatment of varicella-zoster infection in patients at high
      risk.

PMID- 4349545
TI  - [Alternating corticosteroid therapy in chronic polyarthritis].

PMID- 4349547
TI  - On the subunit structure of cytochrome oxidase from beef heart mitochondria.

PMID- 4349546
TI  - Control by TSH of a phospholipase A 2  activity, a limiting factor in the
      biosynthesis of prostaglandins in the thyroid.

PMID- 4349548
TI  - Hydrolysis of sphingomyelin liposomes by sphingomyelinase.

PMID- 4349549
TI  - Conformational differences in the myosin-ADP complex in myofibrils and isolated
      myosin.

PMID- 4349550
TI  - Oxytocin receptor in frog bladder epithelial cells. Relationship of ( 3
      H)oxytocin binding to adenylate cyclase activation.

PMID- 4349551
TI  - On the regulatory properties of a halophilic citrate synthase.

PMID- 4349552
TI  - Ethanol-induced fatty liver: effect of intestinal lymph fistula.

PMID- 4349554
TI  - Optokinetic nystagmus in diseases of the central nervous system.

PMID- 4349555
TI  - Renal renin in experimental nephrosclerosis.

PMID- 4349553
TI  - Facial nerve preservation in relation to tumour size in acoustic nerve tumour
      surgery.

PMID- 4349556
TI  - Causes of elevated perilymph protein concentrations.

PMID- 4349557
TI  - [Infectious mononucleosis].

PMID- 4349558
TI  - [Etiopathogenesis of the psoriatic disease].

PMID- 4349559
TI  - Morphological and biochemical alterations in foetal rat brain cells cultured in
      the presence of monobutyryl cyclic AMP.

PMID- 4349561
TI  - Cholera enterotoxin: failure of anti-inflammatory agents to prevent cyclic AMP
      accumulation.

PMID- 4349560
TI  - Thymus and bone marrow derived lymphatic leukaemia in mice.

PMID- 4349562
TI  - SV40 protection in myeloma oncogenesis.

PMID- 4349563
TI  - Transfer RNA activities of Rous sarcoma and Rous associated viruses.

PMID- 4349564
TI  - Specificity in initiation of protein synthesis in a fractionated mammalian cell
      free system.

PMID- 4349565
TI  - Satellite DNA replication in baby mouse kidney cells infected with polyoma virus.

PMID- 4349566
TI  - F1-histone phosphorylation in metaphase chromosomes of cultured Chinese hamster
      cells.

PMID- 4349567
TI  - Glucocorticoid binding proteins in human leukaemic lymphoblasts.

PMID- 4349568
TI  - Periodic breathing in premature and neonatal babies: incidence, breathing
      pattern, respiratory gas tensions, response to changes in the composition of
      ambient air.

PMID- 4349569
TI  - Studies on ciliary dyskinesia factor in cystic fibrosis. II. Short term leukocyte
      cultures and long term lymphoid lines.

PMID- 4349570
TI  - Poly(adenosine diphosphate ribose).

PMID- 4349571
TI  - [Endoscopic catheterization of the pancreatic ducts. Apropos of 160 cases].

PMID- 4349572
TI  - [Myoid tumors of the stomach (leiomyoblastoma). Apropos of 5 cases].

PMID- 4349574
TI  - [Fibroscopy of the operated stomach. Apropos of 253 patients].

PMID- 4349573
TI  - [The fate of 165 hemorrhagic ulcers treated in a special intensive care unit].

PMID- 4349575
TI  - [Primary biliary cirrhosis with scleroderma, Raynaud's syndrome, telangiectasis
      and thyroid disease].

PMID- 4349576
TI  - [Respective role of microbial growth and resection in diarrhea pathogenesis after
      ileotomy for Regional enteritis. Effects of antibiotic-cholestyramine
      association].

PMID- 4349577
TI  - [Trial treatment of 5 cases of acute Crohn's ileitis with BCG].

PMID- 4349578
TI  - [Rhumatoid rosette phenomenon. (Apropos of 191 cases)].

PMID- 4349579
TI  - [Hyperglycemic coma without keto-acidosis in 2 hypertensive patients treated with
      intravenous diazoxide].

PMID- 4349580
TI  - [Intra-osseous circulation investigation. Medullary function investigation].

PMID- 4349581
TI  - [Tasks of cardiologic dispensaries in the after care for myocardial infarct].

PMID- 4349583
TI  - [Forensic osteology. 3. Determination of individual age by means of skull cap
      thickness, with special reference to hyperostosis frontalis interna (Morgagni
      Henschen)].

PMID- 4349582
TI  - [Current status of antibiotic therapy].

PMID- 4349584
TI  - Calcification in a gastric mucinous adenocarcinoma.

PMID- 4349586
TI  - Preparative-scale synthesis of (1R)-and (1S)-monodeuteriopropanol by enzymatic
      exchange reactions.

PMID- 4349588
TI  - Isolation of DNA and DNA polymerase from MC 29  tumor virus.

PMID- 4349587
TI  - [The ulcerogenic effect of the adrenal cortex and 1,2-dehydrocortisone implanted
      into the stomach walls of rabbits (a histochemical study)].

PMID- 4349589
TI  - [Myocardial function in chronic pulmonary diseases. Fonction of the left
      ventricle in chronic bronchopneumopathies].

PMID- 4349591
TI  - [Poliomyelitis in the Federal Republic of Germany. Sporadic infections by
      imported wild poliovirus].

PMID- 4349590
TI  - Radioisotope brain scans in the diagnosis of brain tumors: technic and
      applications. With emphasis on recognition of lesions outside of the posterior
      fossa.

PMID- 4349592
TI  - [Lipid cytoplasmic inclusions in the interstitial cells of the renal medulla. 1.
      A study of the level of lipid inclusions in experimental neurogenic
      hypertension].

PMID- 4349593
TI  - [Comparative study of the lipid fractions and  32 P-orthophosphate incorporation
      in individual phospholipids from experimental lung tumors and from normal lungs].

PMID- 4349594
TI  - [Epithelial changes of the portio and cervix mucosa with and without the
      influence of ovulation inhibitors].

PMID- 4349595
TI  - Immunological relationship of Brucella with microorganisms of other genera.

PMID- 4349596
TI  - The secretion of dehydroepiandrosterone and dehydroepiandrosterone sulphate in
      man.

PMID- 4349597
TI  - A poxvirus isolated from silvereyes (Zosterops lateralis) from Lower Hutt, New
      Zealand.

PMID- 4349598
TI  - Herpesvirus infection in the black rat (Rattus rattus).

PMID- 4349599
TI  - Stimulation of endogenous respiration of ejaculated ram sperm by dibutyryl cyclic
      AMP.

PMID- 4349600
TI  - Stimulation of division of density inhibited fibroblasts by glucocorticoids.

PMID- 4349601
TI  - Poly (A) and poly (U) in poliovirus double stranded RNA.

PMID- 4349602
TI  - Implications of chemoautotrophism in Mycobacterium leprae.

PMID- 4349603
TI  - Factor in acidified serum toxic for malignant cells in culture.

PMID- 4349604
TI  - [Supervision of the progress of treated malignant cerebral tumours by gamma
      encephalography. (Double labelling technique].

PMID- 4349605
TI  - Collagenase inhibition with penicillamine. Case report.

PMID- 4349607
TI  - Treatment of bilateral breast carcinomas in a patient with silicone-gel breast
      implants. Case report.

PMID- 4349606
TI  - Surgical decisions in the treatment of major salivary gland tumors.

PMID- 4349608
TI  - Effect of 3,7-dimethyl-1-(5-oxo-hexyl)xanthine and 1-hexyl-3,7-dimethyl xanthine
      on cyclic AMP phosphodiesterase of the human umbilical cord vessels.

PMID- 4349609
TI  - A comparison of the effects of methyl methanesulfonate in various reproductive
      toxicity screening tests.

PMID- 4349610
TI  - Actions of lithium on cerebral carbohydrate metabolism.

PMID- 4349611
TI  - Apparent suppression of the tumorigenicity of human cancer cells by cyclic AMP.

PMID- 4349613
TI  - Retinal anlage tumour. A case report.

PMID- 4349612
TI  - [Rapid method for radio-immunochemical determination of plasma renin activity].

PMID- 4349614
TI  - [Osteomalacia, intestinal malabsorption, polyadenopathy and inflammatory
      polyarthritis due to stagnant loop syndrome].

PMID- 4349615
TI  - [Anemia, intestinal hemorrhage and blind loop syndrome].

PMID- 4349616
TI  - [Acquired dysfibrinogenemia and hepatic disorders. Apropos of 30 cases].

PMID- 4349617
TI  - [Prostate cancer and disseminated intravascular blood coagulation].

PMID- 4349618
TI  - [A case of embolic subacute cor pulmonale].

PMID- 4349619
TI  - [Progressive thrombosis of portal system in the course of non-alcoholic
      cirrhosis].

PMID- 4349620
TI  - Genetics of hyperlipidemia in coronary heart disease.

PMID- 4349621
TI  - Nature of defect responsible for familial vitamin D-resistant rickets (VDRR)
      based on radioimmunoassay for parathyroid hormone (PTH).

PMID- 4349622
TI  - In vitro demonstration of iodide-trapping defect but normal thyrotropin (TSH)
      responsiveness in benign and malignant "cold" thyroid nodules.

PMID- 4349623
TI  - The syndrome of hypertension, hyperreninemia and secondary aldosteronism
      associated with renal juxtaglomerular cell tumor (primary reninism).

PMID- 4349624
TI  - Clinical experiences with tumours of the lacrimal gland.

PMID- 4349625
TI  - Pathology of some lacrimal gland tumours.

PMID- 4349626
TI  - Studies on biosynthesis of polymyxin E (colistin). II. Biosynthesis of polymyxin
      E by mutants m-5 and d-13 of Bacillus polymyxa K-1.

PMID- 4349627
TI  - A new approach to hyperlipoproteinemia phenotyping.

PMID- 4349628
TI  - Clarification of some basic vocabulary: terminology today.

PMID- 4349629
TI  - Experimental herpes simplex encephalitis. Treatment with pyrimidine nucleosides.

PMID- 4349630
TI  - Motor nerve terminal and muscle membrane stabilization by diphenylhydantoin
      administration.

PMID- 4349632
TI  - Herpetic meningitis (type 1) in a case of acute leukemia.

PMID- 4349631
TI  - Cerebral arterial spasm. Modification by inhibition of platelet function.

PMID- 4349633
TI  - Spinal ganglion in herpes zoster. A light and electron microscopic study.

PMID- 4349635
TI  - [Cytochemical characteristics of the neurons and neuroglia of the visual region
      of the cat cerebral cortex].

PMID- 4349636
TI  - [Electron paramagnetic resonance spectra of non-oriented free radicals of sulfur
      containing amino acids].

PMID- 4349634
TI  - Genetics and colon cancer.

PMID- 4349637
TI  - [Molecular structure and mechanism of functioning of cytochrome P-450].

PMID- 4349638
TI  - [Electric interaction of parallel non-myelinated nerve fibers. 3. Interaction in
      nerve trunks].

PMID- 4349639
TI  - [Complexity of the primary structure of cytochromes].

PMID- 4349640
TI  - [Characteristics of the thermomechanical parameters of supramolecular DNP-systems
      from neoplastic cells].

PMID- 4349641
TI  - [Study of structural transitions of DNA in a complex with RNA polymerase by the
      spin-label method].

PMID- 4349642
TI  - The glycosaminoglycans of articular cartilage in calcium pyrophosphate dihydrate
      (CPPD) crystal deposition disease (chondrocalcinosis articularis or pyrophosphate
      arthropathy).

PMID- 4349643
TI  - Subcellular fractionation of the enterocyte with special reference to peptide
      hydrolases.

PMID- 4349644
TI  - Comparison of steroidogenic effects of cAMP and dbcAMP in the rat adrenal gland.

PMID- 4349645
TI  - Evidence for a role of adenosine 3',5'-monophosphate in parathyroid hormone
      release.

PMID- 4349646
TI  - Cyclic 3'5'-adenosine monophosphate in isolated bone cells. Response to low
      concentrations of parathyroid hormone.

PMID- 4349647
TI  - On the mechanism of action of luteinizing hormone-releasing factor and prolactin
      release inhibiting factor.

PMID- 4349648
TI  - Regional responses of the pituitary to corticotropin-releasing factor (CRF) and
      ammonium ions.

PMID- 4349649
TI  - Biologic action of 1,25-dihydroxy-vitamin D3 in the rachitic dog.

PMID- 4349651
TI  - Effects of calcium and theophylline on ACTH- and dibutyryl cyclic AMP-stimulated
      steroidogenesis and glycolysis by intact mouse adrenal glands in vitro.

PMID- 4349650
TI  - Effects of some modifiers of insulin secretion on insulin biosynthesis.

PMID- 4349653
TI  - Lack of specificity for the extra-ovarian prolactin effect on vaginal
      mucification in rats.

PMID- 4349652
TI  - Luteinization of transplanted ovarian follicles in the rat induced by dibutyryl
      cyclic AMP.

PMID- 4349654
TI  - The subunit structure of rabbit-skeletal-muscle phosphorylase kinase, and the
      molecular basis of its activation reactions.

PMID- 4349655
TI  - Luminescence quenching in azurin.

PMID- 4349656
TI  - Spin-labelled phosphofructokinase and its interactions with ATP and metal-ATP
      complexes as studied by magnetic-resonance methods.

PMID- 4349658
TI  - Diacetyl (acetoin) reductase from Aerobacter aerogenes. Kinetic studies of the
      reduction of diacetyl to acetoin.

PMID- 4349657
TI  - Transport of lactate and succinate by membrane vesicles of Escherichia coli,
      Bacillus subtilis and a pseudomonas species.

PMID- 4349659
TI  - [Antibiotic therapy. 3. Neomycin derivatives, polymyxins, erythromycins].

PMID- 4349660
TI  - Isolation of viruses, bacteria and other organisms from venereal disease clinic
      patients: methodology and problems associated with multiple isolations.

PMID- 4349661
TI  - Serum lipoproteins of normal and cholesterol-fed rats.
AB  - The density distribution of lipoproteins in rats fed chow or chow containing 1%
      cholesterol and 10% olive oil was studied. Lipoprotein fractions were prepared in
      the ultra-centrifuge between narrow density bands within the density range of
      1.006-1.21 and were analyzed by chemical, electrophoretic, and immunological
      methods. In serum from normal rats there were three major lipoprotein fractions,
      with densities less than 1.006, 1.030-1.063, and 1.063-1.21. Almost no
      lipoprotein was found between d 1.006 and 1.030. Most of the low density
      lipoprotein appeared between a density of 1.04 and 1.05. In the density range
      1.05-1.07, small amounts of both low density and high density lipoprotein were
      found. Feeding a diet high in cholesterol resulted in a marked increase in the
      concentration of lipoproteins of density less than 1.006, and a new lipoprotein
      fraction appeared between d 1.006 and 1.030; this fraction contained
      immunologically demonstrable low density and high density lipoproteins. In
      addition, there was a decrease in the high density lipoprotein fraction between d
      1.070 and 1.21.

PMID- 4349662
TI  - Early changes in plasma lipoprotein structure and biosynthesis in cholesterol-fed
      rabbits.
AB  - Plasma lipoproteins of d < 1.063 g/ml from rabbits fed a diet containing 1%
      cholesterol for 4 days showed changes in concentration and rates of flotation as
      determined by analytical ultracentrifugation. A marked increase in cholesteryl
      ester content of lipoprotein with d < 1.019 g/ml was the most prominent change in
      rabbits fed the diet for 21 days. Gel electrophoresis and immunochemical
      procedures demonstrated that in control and hypercholesterolemic rabbits there
      were some common apolipoproteins found in all lipoproteins with density < 1.063
      g/ml. In control rabbits, there were also apolipoproteins specific to the
      lipoprotein fraction with d < 1.019 and to the fraction with d 1.019-1.063 g/ml.
      However, in rabbits fed the hypercholesterolemic diet for 21 days, the
      apolipoproteins characteristic of fraction 1.019-1.063 were the most abundant in
      the fraction with d < 1.019 g/ml. Liver slices from rabbits fed the high
      cholesterol diet for 7 and 21 days incorporated more l-[(14)C]leucine into very
      low density and low density lipoproteins than controls. The results suggest that
      cholesterol feeding leads to an increase in biosynthesis of lipoproteins with d <
      1.063 g/ml. The newly synthesized lipoprotein contains apolipoproteins similar to
      those found in controls but with a higher lipid-to-protein ratio. From the
      apoprotein composition, it is concluded that the very low density fraction
      present in cholesterol-fed animals is more structurally related to low density
      lipoproteins than to the very low density lipoproteins isolated from control
      animals.

PMID- 4349664
TI  - Identification of mountebank healing artists.

PMID- 4349663
TI  - Effects of ethanol on the metabolism of free fatty acids in isolated liver cells.
AB  - Ethanol inhibited the oxidation and enhanced the esterification of albumin-bound
      [1-(14)C]palmitate incubated with isolated rat liver cells. Ethanol decreased the
      conversion of [1-(14)C]palmitate to (14)CO(2) and (14)C-labeled ketone bodies and
      enhanced the incorporation of [1-(14)C]palmitate into glycerolipids, especially
      triglyceride; cholesteryl ester synthesis was unaffected. The half-maximal
      effective ethanol concentration for each of these processes was 6-10 micro g/ml
      and a maximum effect was produced by about 50 micro g/ml. Ethanol oxidation was
      required for each of these alterations, since the effects were completely
      abolished by pyrazole. The energy obtainable from ethanol oxidation was in excess
      of the energy deficit from decreased fatty acid oxidation. However, ethanol did
      not affect O(2) consumption, indicating that ethanol oxidation replaced the
      oxidation of both fatty acids and other substrates. Ethanol inhibited the citric
      acid cycle in the intact liver cells by 20-30%. The major site of inhibition was
      alpha-ketoglutarate oxidation. Results suggest that ethanol inhibited alpha
      ketoglutarate dehydrogenase in the mitochondria of hepatocytes by elevating the
      mitochondrial NADH:NAD ratio. A minor site of inhibition of ethanol oxidation was
      detected between succinate and citrate. It is suggested that ethanol inhibits
      fatty acid oxidation in hepatocytes by competitive substrate oxidation, resulting
      in an increased availability of long-chain free fatty acids; this thereby
      enhances esterification, leading to accumulation of liver triglyceride.

PMID- 4349665
TI  - [Hypothalamo-anterior pituitary-adrenal cortex system under continuous
      alternating and circadian fluocortolone therapy following kidney
      transplantation].

PMID- 4349666
TI  - Human tumours grown in mice.

PMID- 4349669
TI  - Polymorphism of natural DNA.

PMID- 4349667
TI  - Effects of cytochrome c on liver functions of old rats.

PMID- 4349668
TI  - Forssman reactivity and cell contacts in cultured hamster cells.

PMID- 4349670
TI  - Regulation of phospho-enol-pyruvate carboxykinase during starvation and glucose
      repression.

PMID- 4349671
TI  - Inhibition of adenovirus type 12 induced DNA synthesis in G1-arrested BHK21 cells
      by dibutyryl adenosine cyclic 3':5'-monophosphate.

PMID- 4349672
TI  - Growth control and cyclic alterations of cyclic AMP in the cell cycle.

PMID- 4349673
TI  - Cell line derived from Balb-3T3 that is transformed by murine leukaemia virus: a
      focus assay for leukaemia virus.

PMID- 4349674
TI  - Inhibition of MLV-induced transformation in Balb-3T3 derived cells.

PMID- 4349675
TI  - Sub-clinical involvement of peripheral nerves in Hodgkin's disease.

PMID- 4349676
TI  - The incidence and significance of Australia antigen in cancer patients.

PMID- 4349677
TI  - Stimulation and retardation of limb regeneration by adenosine 3',5'-monophosphate
      and related compounds.

PMID- 4349678
TI  - The neurophysiologic basis of pain.

PMID- 4349679
TI  - Fundamental considerations of chronic pain therapy.

PMID- 4349680
TI  - [Effect of the method of disintegration of Escherichia coli cells on the yield of
      L-asparaginase].

PMID- 4349681
TI  - [Effect of cold treatment of meat on the NAD and NADH2 content and lactate
      dehydrogenase activity in the medial gluteal and greater psoas beef muscles].

PMID- 4349682
TI  - [Free nucleotide content of autolyzing muscles of fish during gamma irradiation].

PMID- 4349683
TI  - [Spontaneous organic hypoglycemia due to pancreatic tumor (functional exploration
      of organic hyperinsulinism)].

PMID- 4349684
TI  - [Hypoglycemia due to extrapancreatic tumor].

PMID- 4349685
TI  - [Parotid tumors].

PMID- 4349686
TI  - [Tumors of the accessory salivary glands of the buccal cavity].

PMID- 4349687
TI  - [Therapeutic experiences with a myotinolytic agent (orphenadrine citrate) in
      vertebral, radicular disorders].

PMID- 4349688
TI  - [Electron microscopy study of the neurohypophysis in normal rats or after
      bilateral adrenalectomy. Study of the pituitary cells and on the mode of release
      of the neurosecretion].

PMID- 4349690
TI  - Chemodectomas of the head and neck.

PMID- 4349689
TI  - [Tumours of the central grey nuclei. A neuro-radiological study with anatomical
      verification].

PMID- 4349691
TI  - Cytomegalic inclusion disease. Report of a case diagnosed radiologically.

PMID- 4349692
TI  - The Tecumseh study of respiratory illness. V. Patterns of infection with the
      parainfluenzaviruses.

PMID- 4349693
TI  - The epidemiology of hepatitis B antigen in a high prevalence area.

PMID- 4349694
TI  - A seroepidemiological study of Epstein-Barr virus and other viral antigens in
      sarcoidosis.

PMID- 4349696
TI  - [Ring layers (annulate lamellae) in the ultrastructure of glioblastoma multiforme
      of the human brain].

PMID- 4349695
TI  - Stimulation of granulation tissue growth in burns.

PMID- 4349697
TI  - [Benign glomus tumors of the stomach].

PMID- 4349698
TI  - [Mixed tumors of the breast].

PMID- 4349699
TI  - [Acquired cytomegalovirus infections. Critical review].

PMID- 4349700
TI  - A mathematical evaluation of tumour growth curves in rapid, intermediate and slow
      growing rat hepatomata.

PMID- 4349702
TI  - [Significance of intranuclear crystalloid inclusions found in human
      oligodendroglioma cells].

PMID- 4349701
TI  - [Development of central monoaminergic neurons in the guinea pig fetus].

PMID- 4349704
TI  - [Effect of PMS and HCG on testicular ascorbic acid content in Bufo arenarum
      Hensel].

PMID- 4349703
TI  - [Mechanism of oxidations in Pseudomonas fluorescens. VII. Oxidation of NADH by
      nonproliferating S type suspensions].

PMID- 4349705
TI  - [Effects of exogenous mineral silicium on inorganic components of different
      tissues in atheromatous rabbits].

PMID- 4349706
TI  - Conformational and biological properties of partial sequences of glucagon.

PMID- 4349707
TI  - Expectancy and the pituitary-adrenal system.

PMID- 4349708
TI  - Coexistent herpes simplex encephalitis and malignant astrocytoma. A
      clinicopathologic study of three cases.

PMID- 4349709
TI  - Immunoglobulins and EB virus antibodies in infectious mononucleosis.

PMID- 4349710
TI  - Serum autoantibodies in hepatitis associated antigen (HAA) positive patients. A
      possible index of cell-mediated immunity to the associated-infective agent.

PMID- 4349711
TI  - Intracellular IgA immunoglobulin crystals in chronic lymphocytic leukaemia.

PMID- 4349712
TI  - Enzymic degradation of cartilage in osteoarthritis.

PMID- 4349713
TI  - [On the antigenicity of some injectable tissue extracts. II].

PMID- 4349714
TI  - A comparative study of five laboratory tests for foeto-placental dysfunction in
      late pregnancy.
AB  - Five foeto-placental function tests were studied in parallel in normal and
      abnormal late pregnancies with a view to establishing which test or tests is most
      satisfactorily able to identify the mother whose foetus is in danger.A critical
      examination of the levels in blood serum of two enzymes, placental phosphatase
      isoenzyme and cystine aminopeptidase, the polypeptide hormone placental lactogen
      (chorionic somatomammotrophin), and the oestrogen oestriol-17beta is described.A
      correlation was attempted beween clinical data and the results of the above
      laboratory analyses and also with the daily urine oestrogen output. The plasma
      and urine oestriol levels proved generally to be the more useful warning tests in
      late pregnancy, whilst the plasma cystine aminopeptidase was the least sensitive
      indicator of foeto-placental dysfunction.

PMID- 4349715
TI  - Selective media in the isolation of tubercle bacilli from tissues.
AB  - Direct culture on Lowenstein-Jensen slopes and on three media made selective for
      tubercle bacilli by the addition of four antibacterial agents was compared with
      guinea-pig inoculation on 490 tissue specimens. Tubercle bacilli were obtained
      from 15 specimens by culture and 14 by guinea-pig inoculation; only one specimen
      was positive by guinea-pig and not by culture. The most efficient culture medium
      was a selective 7H11 slope. Routine guinea-pig inoculation has been replaced by a
      wider range of culture procedures.

PMID- 4349716
TI  - Distribution of  14 C-isoxazole in adrenals, ovaries, and breast carcinoma.

PMID- 4349717
TI  - Caval-portal shunting as a cause of a focal increase in radiocolloid uptake in
      normal livers.

PMID- 4349718
TI  - Localization of  99m Tc in the choroid plexus of the fourth ventricle.

PMID- 4349720
TI  - Evidence for naturally occurring murine sarcoma virus.

PMID- 4349719
TI  - Concentration of selected intravenously administered antibiotics in experimental
      surgical wounds.

PMID- 4349721
TI  - Puromycin stimulation of rat liver ornithine decarboxylase activity.

PMID- 4349722
TI  - Prostaglandin E2: effects on aggregation, shape change and cyclic AMP of rat
      platelets.

PMID- 4349723
TI  - Effects of a prostaglandin antagonist, polyphloretin phosphate, on basal and
      stimulated thyroid function.

PMID- 4349724
TI  - Properties of 15-hydroxy prostaglandin dehydrogenase: structural requirements for
      substrate binding.

PMID- 4349725
TI  - Reversibility of 15-OH prostaglandin dehydrogenase from swine lung.

PMID- 4349726
TI  - Radioimmunoassay of prostaglandins, angiotensin, digoxin, morphine and adenosine
      3',5'-cyclic-monophosphate with nitrocellulose membranes.

PMID- 4349728
TI  - Pitfalls of local excision in the treatment of carcinoma of the breast.

PMID- 4349727
TI  - Resection of the inferior vena cava for adjacent malignant diseases.

PMID- 4349729
TI  - Long term survivors after resection of bronchial carcinoma.

PMID- 4349730
TI  - Summary of recent abstracts. II. Amoebiasis and intestinal protozoal infections.

PMID- 4349731
TI  - [Clinical aspects, diagnosis and treatment of influenza and other acute
      respiratory diseases].

PMID- 4349732
TI  - [Glomus tumors of the stomach (2 observations)].

PMID- 4349733
TI  - [Toxicity and antineoplastic activity of a new thio-TEPA analog].

PMID- 4349734
TI  - [Morphological changes in the liver of Lebistes reticulatus fish due to the
      administration of diethyl- and dimethylnitrosoamines].

PMID- 4349735
TI  - [Infectious complications in disorders of granulopoiesis].

PMID- 4349736
TI  - [Roentgen diagnosis of tumors of the jugular glomus].

PMID- 4349737
TI  - A therapeutic aftercare setting for "refractory" chronic schizophrenic patients.

PMID- 4349738
TI  - Proteoglycans-collagen interactions in human costal cartilage.

PMID- 4349739
TI  - Primary structure of cytochrome c from the emu, Dromaeus novaehollandiae.

PMID- 4349740
TI  - [Scopolamine in the emergency treatment of respiratory failure in very severe
      encephalitis B].

PMID- 4349741
TI  - Cyclic adenosine monophosphate and cardiac contractility.

PMID- 4349743
TI  - Isolation and identification of phospholipids from root tip cell plasmalemma of
      Phaseolus limensis.

PMID- 4349742
TI  - Substrate requirements for angiotensin I conversion in vivo and in vitro.

PMID- 4349744
TI  - Comparative studies on the effects of aminoglutethimide, metopirone, ACTH and
      hydrocortisone on the adrenal cortex of adult male rats. II. Histological and
      histochemical studies.

PMID- 4349746
TI  - [Arterial hypertension and mineralocorticoids].

PMID- 4349747
TI  - Effect of angiotensin on water and electrolyte excretion in normal and cirrhotic
      rats.

PMID- 4349745
TI  - [Binding of 17-alpha-ethinyl estradiol and mestranol to uterine and pituitary
      gland receptors of the rat in vitro].

PMID- 4349748
TI  - Histochemical alterations in tissue culture produced by enteroviruses.

PMID- 4349749
TI  - Cytomegalovirus infection of two neonates with evidence of lympho-proliferation.

PMID- 4349750
TI  - Inhibition of macrophage migration by a proteoglycan extracted from Kurloff cells
      of the guinea-pig.

PMID- 4349751
TI  - Virus-induced diabetes mellitus. I. Hyperglycemia and hypoinsulinemia in mice
      infected with encephalomyocarditis virus.
AB  - Infection of DBA/2N male mice with encephalomyocarditis virus resulted in a
      diabeteslike syndrome characterized by hyperglycemia, glycosuria,
      hypoinsulinemia, polydipsia, and polyphagia. Blood glucose levels were elevated
      within 4 days after infection and reached a maximum mean level of 320 mg/100 ml
      within 12 days. Approximately 60-80% of the animals developed a transient
      hyperglycemia while 10-15% of the animals remained hyperglycemic for well over 6
      mo. The remaining animals failed to become hyperglycemic but many had abnormal
      glucose tolerance curves. Hyperglycemia was most pronounced when animals were
      allowed free access to food, and the incidence of byperglycemia was related both
      to the strain and sex of the animals, with few females developing hyperglycemia.
      The amount of immunoreactive insulin in the plasma of infected hyperglycemic mice
      was significantly lower than in appropriate controls, and injection of exogenous
      insulin resulted in a rapid drop in the blood glucose levels. Despite the fact
      that certain animals were hyperglycemic for many months, virus could not be
      recovered from the pancreas after the first 10 days of the infection.

PMID- 4349752
TI  - The influence of the partner cell on the production of L virus and the expression
      of viral surface antigen in hybrid cells.
AB  - The C-type particles produced by the A9 and A9HT sublines of mouse L cells were
      shown to infect C3H (N type), but not C57BL (B type), mouse embryo fibroblasts.
      Infection was indicated by distinct single giant cell formation in the XC
      monolayer used to overlay the mouse embryo fibroblasts. On the basis of these
      results it was concluded that the L cell virus is N tropic. A9 and A9HT cells
      were fused to various mouse cells derived from tumors and normal tissues. The
      ability to produce the Moloney-type surface antigen and to release infectious
      virus was introduced by the A9 component into the hybrid cell. Virus production,
      measured by antigen induction on JLS-V9 cells, was suppressed in those hybrids in
      which the partner cell had a genotype determining low infectibility with that
      particular virus (B-type cell). It thus appears that the major genetic locus
      affecting resistance to infection with leukemia viruses, the Fv-1 locus,
      regulates infectious virus production in somatic cell hybrids also. The same
      genetic locus did not seem to govern the expression of all virus-related
      functions, for the virus-determined membrane antigen was demonstrated in many of
      the N x B-type hybrids in which production of infectious virus was suppressed.

PMID- 4349755
TI  - [A case of isolated ACTH deficiency].

PMID- 4349756
TI  - Studies on polynucleotides. CXVI. A further study of the T4 ligase-catalyzed
      joining of DNA at base-paired ends.

PMID- 4349757
TI  - Replication of polyoma DNA in isolated nuclei. I. Characterization of the system
      from mouse fibroblast 3T6 cells.

PMID- 4349758
TI  - Replication of polyoma DNA in isolated nuclei. II. Evidence for semi-conservative
      replication.

PMID- 4349759
TI  - Polypeptide conformation of cytoplasmic malate dehydrogenase from an electron
      density map at 3.0 angstrom resolution.

PMID- 4349761
TI  - Isolation and some distinctive properties of a new type of recombination
      deficient mutant of Bacillus subtilis.

PMID- 4349762
TI  - Antigen expression and colony formation of lymphoblastoid cell lines after
      superinfection with Epstein-Barr virus.

PMID- 4349760
TI  - Regulation of skeletal muscle contraction. II. Structural studies of the
      interaction of the tropomyosin-troponin complex with actin.

PMID- 4349763
TI  - DNA polymerase activity and DNA synthesis in preneoplastic nodule outgrowths of
      BALB-c and C3H mouse mammary gland.

PMID- 4349764
TI  - Production and characterization of human cell-adapted murine Rauscher virus
      pseudotype of murine sarcoma virus.

PMID- 4349765
TI  - Induction of bladder cancer in hamsters by repeated intratracheal administrations
      of 2-acetylaminofluorene.

PMID- 4349766
TI  - Comparative studies on Visna, progressive pneumonia, and Rous sarcoma viruses by
      electron microscopy.

PMID- 4349767
TI  - Occurrence of a primary liver carcinoma in a Rhesus monkey fed aflatoxin B 1 .

PMID- 4349768
TI  - Cyclic adenosine 3',5'-monophosphate in the control of melanoma cell replication
      and differentiation.

PMID- 4349769
TI  - Release of mouse leukemia-sarcoma virus from synchronized cells.

PMID- 4349770
TI  - Hepatoma with unusual associations.

PMID- 4349771
TI  - Malignant, non-functional, non-chromaffin paraganglioma of the retroperitoneum.

PMID- 4349773
TI  - Phospholipids of marine origin. VI. The octopus (Octopus vulgaris).

PMID- 4349772
TI  - The action of calcium at spinal neurones of the frog.
AB  - 1. The action of Ca on membrane excitability and synaptic transmission at
      motoneurones of the isolated spinal cord of the frog has been studied.2. Impulse
      propagation along presynaptic fibres was unaffected by [Ca] in the range of 0-10
      mM in the presence of 1 mM-Mg.3. Motoneurone membrane excitability was within
      normal ranges when the cord was bathed in low or 0 Ca solutions containing 1 mM
      Mg but was depressed in 5 or 10 mM-Ca solutions.4. Spontaneous miniature synaptic
      potentials were recorded in the presence of tetrodotoxin. The frequencies were
      reduced but not abolished in the absence of bath Ca, but were increased greater
      than twofold in 5 or 10 mM-Ca in comparison to those in normal Ringer solution (1
      mM-Ca).5. Iontophoretic application of Ca both near to and remotely from the
      intracellular recording site (presumably in the soma) caused facilitation of
      elicited post-synaptic potentials.6. It is concluded that the action of Ca at
      these central synapses is identical to that described at the neuromuscular
      junction.

PMID- 4349775
TI  - Synthesis of the arabinose operon regulator protein in a cell-free system.

PMID- 4349774
TI  - [Current concepts concerning the pathogenesis and treatment of Itsenko-Cushing
      disease].

PMID- 4349776
TI  - Superinfection with Epstein-Barr virus of human lymphoid cell lines of different
      origin.

PMID- 4349777
TI  - Foetal liver tRNA phe  in rat hepatoma.

PMID- 4349778
TI  - Extraction of soluble gonadotrophin receptors from rat testis.

PMID- 4349779
TI  - Androgen "receptor" in rat liver: cytosol "receptor" deficiency in
      pseudohermaphrodite male rats.

PMID- 4349780
TI  - Dopamine: excitatory and inhibitory transmission from a giant dopamine neurone.

PMID- 4349781
TI  - Chlorophyll interactions and light conversion in photosynthesis.

PMID- 4349782
TI  - In vivo binding of tritiated actinomycin to cellular chromatin.

PMID- 4349783
TI  - Effect of human calcitonin on the sarcoplasmic reticulum of the human heart.

PMID- 4349784
TI  - Recovery of cerebral energy metabolism after complete ischemia of one hour's
      duration.

PMID- 4349785
TI  - Carcinogenicity of  -hydroxylated dipropylnitrosamine.

PMID- 4349786
TI  - Calcium transport and mobilization mediated by 1,25-dihydroxycholecalciferol.

PMID- 4349787
TI  - [Epithelial tumors of the salivary glands containing lymphatic tissue. 3. Remarks
      on the pathogenesis of lymphoepithelial tumors of the salivary glands].

PMID- 4349788
TI  - Medical and surgical management of stroke.

PMID- 4349790
TI  - [Pathogenesis and treatment of lightning and nutatory seizures].

PMID- 4349789
TI  - [Inhibitors of immunopoiesis in the complex therapy of childhood cerebral palsy].

PMID- 4349791
TI  - A possible explanation for spontaneous breast development in XY gonadal
      dysgenesis.

PMID- 4349793
TI  - Arterial baroreceptor fibers in the recurrent laryngeal nerve.

PMID- 4349792
TI  - Mucociliary function during experimentally induced rhinovirus infection in man.

PMID- 4349794
TI  - Idiopathic facial palsy and pregnancy.

PMID- 4349795
TI  - Oxidation of formate and oxalate in peroxisomal preparations from leaves of
      spinach beet (Beta vulgaris L.).

PMID- 4349796
TI  - Cyclic AMP-dependent diphosphoinositide kinase.

PMID- 4349797
TI  - Cyclic AMP levels in various tissues of the domestic fowl (Gallus domesticus) as
      affected by glucagon, epinephrine and insulin.

PMID- 4349798
TI  - Adenylate cyclase and the function of cyclic adenosine 3':5'-monophosphate in the
      leucocidin-treated leucocyte.

PMID- 4349799
TI  - The effect of adenine nucleotides and dehydroepiandrosterone on the isoenzymes of
      NADP + -and NAD + -glucose-6-phosphate dehydrogenase and 6-phosphogluconate
      dehydrogenase from rat adipose tissue.

PMID- 4349800
TI  - [Changes in the normal ECG during sleep. Simultaneous ECG-EEG leads during
      wakefulness and during the 1st sleep-cycle].

PMID- 4349802
TI  - [Cyclic AMP].

PMID- 4349801
TI  - [Dietary plans in the treatment of hyperlipoproteinemia].

PMID- 4349803
TI  - The antiquity of age-associated bone demineralization in man.

PMID- 4349804
TI  - Adenohypophysis of foetal sheep: correlation of ultrastructure with functional
      activity.

PMID- 4349805
TI  - Structure and physiology of denervated and re-innervated cockroach muscle.

PMID- 4349806
TI  - Prevention by angiotensin II antiserum of drinking induced by intracranial
      angiotensin.

PMID- 4349807
TI  - Early and late facilitation of transmission through a sympathetic ganglion and
      the influence of preganglionic B and C fibres.

PMID- 4349808
TI  - Calcium release and vasopressin action in toad bladder.

PMID- 4349810
TI  - Surgical treatment of juvenile nasopharyngeal angiofibroma.

PMID- 4349809
TI  - Electrophysiological identification of cell bodies of the tubero-infundibular
      neurones in the rat.
AB  - 1. Electrical stimulation of the median eminence induced unit responses in the
      suprachiasmatic, the ventromedial and the arcuate nuclei of the hypothalamus in
      the female rat anaesthetized with urethane.2. Arcuate units with constant latency
      responded in one to one fashion to repetitive stimuli up to 286 Hz.3. A
      conditioning stimulus just above threshold increased the threshold and latency
      for responses produced by a test stimulus given within 6 msec after the
      conditioning stimulus. Absolute refractory period was 1.4-2.0msec.4. A
      conditioning stimulus just below threshold did not alter the threshold and
      latency of the responses to test stimuli at any interval.5. A stimulus given
      within a time period following a spontaneously occurring spike failed to induce a
      unit response.6. It is concluded that the arcuate nucleus of the hypothalamus
      includes cell bodies of origin of the tubero-infundibular axons in the rat.

PMID- 4349811
TI  - Radiographic evaluation of the prevertebral space.

PMID- 4349814
TI  - [Ultrastructural studies of the fusion of human erythrocytes with Sendai virus].

PMID- 4349813
TI  - The arterial wall and the process of atherosclerosis.

PMID- 4349812
TI  - Effects on self-stimulation behavior of drugs influencing dopaminergic
      neurotransmission mechanisms.

PMID- 4349815
TI  - [Are tumors caused by DNA viruses?].

PMID- 4349816
TI  - Changes in neuron structure during action potential propagation and synaptic
      transmission.

PMID- 4349817
TI  - The in vitro assay of the herpesvirus of turkeys.

PMID- 4349818
TI  - Karyological characterization of primary dog kidney cells in regard to
      acceptability of the cells as substrate of virus vaccines.

PMID- 4349819
TI  - New trends in the preparation of cell substrates for the production of virus
      vaccines.

PMID- 4349820
TI  - Replacement of serum by a soybean protein fraction in a basal tissue culture
      medium.

PMID- 4349821
TI  - Consideration of immunological prophylaxis of tumours.

PMID- 4349822
TI  - General discussion the papers of session 3. Developments with viral vaccines.

PMID- 4349824
TI  - Carcinogenesis in germ-free animals.

PMID- 4349823
TI  - Problems in the detection of the oncogenic potential of viruses or cell cultures.

PMID- 4349826
TI  - Search for oncogenes in human rhabdomyosarcoma cells.

PMID- 4349825
TI  - Natural history studies of the feline RNA tumor virus genoma. I. Detection of
      group specific antigen and C-type particles.

PMID- 4349827
TI  - Cell tumourigenicity detected by heterotransplantation into mice immunosuppressed
      with anti-lymphocytic serum.

PMID- 4349828
TI  - Study of two double-stranded ribonucleic acids of viral origin: interferon
      inducing and antiviral activities.

PMID- 4349829
TI  - A bacterial protein inducing antiviral resistance and high titers of interferon.

PMID- 4349830
TI  - Antiviral properties of five strains of Corynebacterium.

PMID- 4349831
TI  - The development of different vaccine types against parainfluenza-3 in cattle.

PMID- 4349833
TI  - Developments with bacterial vaccines: cholera.

PMID- 4349832
TI  - Safety and potency of parainfluenza-3 vaccines for cattle and test procedures.

PMID- 4349834
TI  - Possible reasons for the inefficiency of Gram-negative bacterial vaccines.

PMID- 4349835
TI  - In vitro infection of sera containing Australia antigen.

PMID- 4349836
TI  - Brief latency click-evoked potentials during waking and sleep in man.

PMID- 4349837
TI  - The effect of methotrexate and folinic acid therapy on the platelet count.

PMID- 4349838
TI  - [Alpha 1 antitrypsin homozygous deficiency associated with chronic respiratory
      diseases. Report of 7 cases observed among 600 subjects examined].

PMID- 4349839
TI  - [Tuberculin hypersensitivity].

PMID- 4349840
TI  - [Routine search for inappropriate secretion of antidiuretic hormone in primary
      bronchial cancers].

PMID- 4349841
TI  - [Asthmatic bronchitis and asthma-like bronchitis in adults].

PMID- 4349842
TI  - [Functional criteria of disodium cromoglycate effects. Value of the measurement
      of the dynamic respiratory work].

PMID- 4349843
TI  - [Bronchotracheal localizations of granular cell tumors or Abrikossoff tumors].

PMID- 4349844
TI  - [Growth hormone and diabetic microangiopathy].

PMID- 4349845
TI  - The inhibition of a p-nitrophenylphosphatase of Streptococcus mutans by fluoride
      ions.

PMID- 4349847
TI  - [Stochastic analysis of eye movements during sleep and neurological syndromes].

PMID- 4349846
TI  - [Kinetics of radioactive iron in blood donors].

PMID- 4349848
TI  - Pancreatic glucagon in health and disease.

PMID- 4349849
TI  - Mammary adenoid cystic carcinoma with unusual features.

PMID- 4349850
TI  - Myofiber inclusions.

PMID- 4349852
TI  - Traumatic optic neuritis.

PMID- 4349851
TI  - Collagenase inhibitors (penicillamine).

PMID- 4349853
TI  - [Demonstration of perchlorate in the urine].

PMID- 4349854
TI  - [Combination of the Rh-deletion type and silent Fy-gene].

PMID- 4349856
TI  - Subacute demyelinating disease in an adult (diffuse-disseminated sclerosis).
      Electron microscopic findings.

PMID- 4349855
TI  - Effects of (H + ), (Na + ), (K + ) and certain membrane-active drugs on
      glycolysis, motility, and ATP synthesis by human spermatozoa.

PMID- 4349857
TI  - Responses evoked from the thalamic centrum medianum by painful input: suppression
      by dorsal funiculus conditioning.

PMID- 4349858
TI  - Epstein-Barr virus in human tumor cells.

PMID- 4349859
TI  - The biology of the mouse mammary tumor virus.

PMID- 4349860
TI  - Properties and mode of action of a partially purified deoxyribonucleic acid
      polymerase from the mitochondria of HeLa cells.

PMID- 4349861
TI  - Synthesis of mitochondrial deoxyribonucleic acid with a partially purified
      deoxyribonucleic acid polymerase from the mitochondria of HeLa cells.

PMID- 4349862
TI  - Orientation of the cell membrane in ghosts and electron transport particles of
      Mycobacterium phlei.

PMID- 4349863
TI  - A comparison of associated enzyme activities in various deoxyribonucleic acid
      polymerases.

PMID- 4349865
TI  - Horse liver alcohol dehydrogenase. Amino groups and rate-limiting steps in
      catalysis.

PMID- 4349864
TI  - Cyanide-insensitive respiration. I. The steady states of skunk cabbage spadix and
      bean hypocotyl mitochondria.

PMID- 4349866
TI  - Mechanism of control of hepatic glycogenesis by insulin.

PMID- 4349867
TI  - Nicotinate phosphoribosyltransferase of human erythrocytes. Purification and
      properties.

PMID- 4349868
TI  - Interaction of concanavalin A and wheat germ agglutinin with the insulin receptor
      of fat cells and liver.

PMID- 4349869
TI  - Anthranilate synthetase of Acinetobacter calcoaceticus. Separation and partial
      characterization of subunits.

PMID- 4349870
TI  - The endometrial adenosine cyclic 3':5'-monophosphate-dependent protein kinase.
      Distribution, subunit structure, and kinetics of adenosine cyclic 3':5'
      monophosphate binding.

PMID- 4349871
TI  - Influence of glucagon on the metabolism of xylitol and dihydroxyacetone in the
      isolated perfused rat liver.

PMID- 4349872
TI  - Structure-function relationships at the active site of nuclease-T'.

PMID- 4349873
TI  - Myocardial ultrastructure of young and senescent rats.

PMID- 4349874
TI  - Periodic fibrillar material in membrane-bound bodies in notochordal epithelium of
      the early chick embryo.

PMID- 4349875
TI  - Ultrastructure of sinus venosus innervation in Petromyzon marinus.

PMID- 4349876
TI  - Electron microscopical study on the influence of the preparative conditions on
      contour length and structure of mitochondrial DNA of mouse liver.

PMID- 4349877
TI  - From vitamin to hormone.

PMID- 4349878
TI  - Synergistic role of intestinal flagellates and normal intestinal bacteria in a
      post-weaning mortality of mice.

PMID- 4349879
TI  - Age related changes of hematologic values in infant Macaca mulatta.

PMID- 4349880
TI  - Review of recent epizootics in nonhuman primate colonies and their relation to
      man.

PMID- 4349881
TI  - Filariasis in New World monkeys: histochemical differentiation of circulating
      microfilariae.

PMID- 4349882
TI  - Relationship of the vaginal smear to ovarian follicles and the uterus in
      postpartum Mongolian gerbils.

PMID- 4349883
TI  - Infections among Thai gibbons and humans caused by atypical Microsporum canis.

PMID- 4349884
TI  - Investigations into the diagnosis and spread of epizootic simian tubrculosis.

PMID- 4349885
TI  - Immune and pathologic consequences of spontaneous Cuterebra myiasis in domestic
      rabbits (Oryctolagus cuniculus).

PMID- 4349886
TI  - The Afghan pika (Ochotona refescens rufescens): a new laboratory animal.

PMID- 4349887
TI  - Collection of chimpanzee semen with an artificial vagina.

PMID- 4349888
TI  - A simple method for skin grafting in germfree mice.

PMID- 4349889
TI  - Pneumothorax associated with lung mite lesions in a rhesus monkey.

PMID- 4349890
TI  - Growth, longevity, and reproductive life of the Mongolian gerbil.

PMID- 4349891
TI  - A simple endotracheal intubation technic for inhalation anesthesia of the rat.

PMID- 4349892
TI  - Subclinical otitis media associated with Pasteurella multocida infections in New
      Zealand white rabbits (Oryctolagus cuniculus).

PMID- 4349893
TI  - Adamantinoma in a spider monkey (Ateles fusciceps).

PMID- 4349894
TI  - A collapsible restraint apparatus for cardiac bleeding of rabbits.

PMID- 4349895
TI  - Tattooing rabbits' ears for identification.

PMID- 4349897
TI  - Thorns of South American clump palm trees in the thoracic organs of owl monkeys
      (Aotus trivirgatus).

PMID- 4349896
TI  - Microsporidiosis (encephalitozoonosis) in the guinea pig.

PMID- 4349898
TI  - Note on the rabbit ovary.

PMID- 4349899
TI  - Pathogenesis of intrauterine infections in rats due to reovirus type 3. I.
      Virologic studies.

PMID- 4349900
TI  - Protein and messenger RNA requirements for superhelicity of polyoma virus DNA.

PMID- 4349901
TI  - DNA virus inhibitory activity of 1- -D-arabinofuranosylcytosine-3',5'-cyclic
      phosphate.

PMID- 4349902
TI  - Differential effect of cytochalasin B on normal and transformed mouse cells.

PMID- 4349903
TI  - [Pseudorheumatic pain conditions in disorders of the peripheral nervous system].

PMID- 4349904
TI  - [Oral contraceptives and hypertension].

PMID- 4349905
TI  - Management of tumors of the parotid gland.

PMID- 4349906
TI  - Management of cancer of the parotid gland.

PMID- 4349908
TI  - [Glomangioma of the vulva. A painful benign tumor in the vulva].

PMID- 4349907
TI  - Nasopharyngeal cancer.

PMID- 4349909
TI  - [Growth regulation of hematopoiesis and humoral control of cell division].

PMID- 4349910
TI  - Bile acid excretion after disappearance of jaundice in intrahepatic cholestasis
      of infancy.

PMID- 4349911
TI  - Collagenolytic activity in periodontal disease.

PMID- 4349912
TI  - Aunt Libby and her cure-alls.

PMID- 4349913
TI  - [Nuclear inclusions in neuropathology].

PMID- 4349914
TI  - [Modifications of the lumbar sympathetic system in aged diabetic patients.
      Histochemical and ultrastructural study].

PMID- 4349915
TI  - Water and cytochrome oxidation-reduction reactions.

PMID- 4349916
TI  - The interaction between the mitochondrial ATPase (F 1 ) and the ATPase inhibitor.

PMID- 4349917
TI  - Cytochrome oxidase from Pseudomonas aeruginosa. I. Purification and some
      properties.

PMID- 4349918
TI  - Cytochrome c-556, a di-heme protein from Pseudomonas aeruginosa.

PMID- 4349919
TI  - Electron paramagnetic resonance studies on nitrogenase. II. Interaction of
      adenosine 5'-triphosphate with azoferredoxin.

PMID- 4349920
TI  - Electron paramagnetic resonance studies on nitrogenase. 3. Function of magnesium
      adenosine 5'-triphosphate and adenosine 5'-diphosphate in catalysis by
      nitrogenase.

PMID- 4349921
TI  - [Studies of cytochrome b-563 and P700 in three non-photosynthetic mutants of
      Chlamydomonas reinhardti].

PMID- 4349922
TI  - The EPR spectrum of isolated complex 3.

PMID- 4349923
TI  - Nuclear magnetic resonance study of the interaction of cytochrome c with
      cytochrome c peroxidase.

PMID- 4349924
TI  - Biochemical basis for the toxic effects of triethyl lead.

PMID- 4349925
TI  - Malignancy of bronchial adenoma.

PMID- 4349926
TI  - [Chronic bronchitis and bronchoscopy].

PMID- 4349927
TI  - [Place of chemotherapy in the treatment of primary bronchial cancers].

PMID- 4349928
TI  - The role of heparin in the chemotherapy of solid tumors: preliminary clinical
      trial in carcinoma of the lung.

PMID- 4349929
TI  - Influence of hormones on the growth of hepatomas and induction of adenylate and
      pyruvate kinases.

PMID- 4349930
TI  - Effect of alkylating antitumor agents on the binding of DNA to protein.

PMID- 4349931
TI  - The mineral content and water compartments of liver and of Morris hepatomata
      5123tc and 3924A and the changes of composition occurring during necrosis in
      hepatoma 3924A.

PMID- 4349932
TI  - The net extrusion of calcium and its temporal relation to the accumulation of
      potassium in slices of rat liver and of Morris hepatomata 5123tc and 3924A.

PMID- 4349933
TI  - Lysosomal hyaluronidase activity in normal rat liver and in chemically induced
      hepatomas.

PMID- 4349934
TI  - Orotate phosphoribosyl transferase and orotidylic acid decarboxylase activities
      in liver and Morris hepatomas.

PMID- 4349935
TI  - A morphological and histochemical study of carcinogenesis of the liver in rats
      fed 3'-methyl-4-dimethylaminoazobenzene.

PMID- 4349936
TI  - Partial characterization of the DNA-dependent DNA polymerases of rat liver and
      hepatoma.

PMID- 4349937
TI  - Carcinoma of the rectum: treatment by anterior resection or abdominoperineal
      excision?

PMID- 4349938
TI  - The influence of dibutyryl cyclic adenosine monophosphate and other substances on
      human bronchial mucous gland discharge.

PMID- 4349939
TI  - Arterial endothelial permeability and vascular disease. The "trap door" effect.

PMID- 4349940
TI  - [Plasma renin in patients with congestive heart failure].

PMID- 4349942
TI  - [Wilms' tumor in an adult].

PMID- 4349941
TI  - The ageing pattern of human intervertebral disc.

PMID- 4349943
TI  - Formation of H adduct radicals in cytosine and its derivatives.

PMID- 4349944
TI  - Pseudoachondroplastic dwarfism. A rough-surfaced endoplasmic reticulum storage
      disorder.

PMID- 4349945
TI  - Metaphyseal dysotosis: description of an ultrastructural defect in the epiphyseal
      plate chondrocytes.

PMID- 4349946
TI  - Alterations in cyclic AMP metabolism in human bronchial asthma. II. Leukocyte and
      lymphocyte responses to prostaglandins.
AB  - In an effort to clarify the basis for the reduced cyclic AMP response to
      catecholamines in leukocytes and lymphocytes from asthmatic donors the response
      of these cells to prostaglandins has been examined. Cells with an impaired beta
      adrenergic response had an essentially unaltered response to prostaglandin E(1)
      (PGE(1)) indicating the presence of selective beta adrenergic blockade. In
      contrast to what was observed with cells from asthmatic individuals, in normal
      control leukocytes with reduced catecholamine responsiveness PGE(1) responses
      were usually reduced as well, suggesting a different mechanism. The excellent
      cyclic AMP response to PGE(1) in cells from asthmatic donors would suggest that
      the defect in catecholamine responsiveness is at the level of the beta adrenergic
      receptor although a contributory role of altered substrate concentrations or
      increased phosphodiesterase activity is not formally excluded.

PMID- 4349947
TI  - Alterations in cyclic AMP metabolism in human bronchial asthma. 3. Leukocyte and
      lymphocyte responses to steroids.
AB  - On the basis of serial studies the responsiveness of leukocytes and lymphocytes
      from asthmatic donors to catecholamines was increased during high dose
      corticosteroid therapy. Similar changes were observed in the cells of normal
      control subjects given 200 mg of hydrocortisone intravenously. The increase in
      responsiveness did not appear to be due to changes in lymphocyte subpopulations
      although this may be a contributing factor. In an effort to elucidate the basis
      for the improved response, in vitro effects of glucocorticoids on lymphocyte
      cyclic AMP concentrations were investigated. Glucocorticoids (prednisolone
      succinate, hydrocortisone, hydrocortisone phosphate, and hydrocortisone
      succinate) stimulated cyclic AMP accumulation in asthma and normal control
      lymphocytes, increases occurring within the first 2 min of incubation. In the
      absence of theophylline, responses were regularly obtained at 10 muM
      hydrocortisone and usually at 1 muM hydrocortisone but not at submicromolar
      steroid concentrations. Theophylline potentiated the cyclic AMP response to
      glucocorticoids and also increased the percentage of positive responses in the
      0.01-1.0 muM corticosteroid range. Combinations of 1 muM hydrocortisone and 1 muM
      epinephrine were sometimes additive or synergistic but in many instances higher
      glucocorticoid concentrations were needed to obtain augmentation of the
      catecholamine response. The in vitro glucocorticoid effects may not fully explain
      their potentiating action in vivo.

PMID- 4349949
TI  - Effect of conjugated dihydroxy bile salts on electrolyte transport in rat colon.
AB  - The mechanism by which excess quantities of bile salts in the colon produce
      diarrhea is not known. Therefore, experiments were performed in which the effect
      of conjugated dihydroxy bile salts on ion transport was evaluated in the in vitro
      short-circuited rat colon. 2 mM glycochenodeoxycholic acid (GCDC),
      taurochenodeoxycholic acid (TCDC), or taurodeoxycholic acid caused a prompt
      increase in short-circuit current (I(sc)) and electrical potential difference
      (PD). Similar results were obtained when theophylline was added. Removal of
      HCO(2) and C1 prevented the effects of both bile salts and theophylline.
      Pretreatment with theophylline blocked the increase in I(sc) and PD produced by
      TCDC and pretreatment with either TCDC or GCDC inhibited the expected
      theophylline response. Na fluxes in the presence of both TCDC and theophylline
      demonstrated a decrease in net absorption; and TCDC decreased net C1 absorption
      and theophylline caused a reversal of net C1 absorption to net C1 secretion. It
      is proposed that the diarrhea associated with cholerheic enteropathy is produced
      by active anion secretion possibly mediated by cyclic AMP.

PMID- 4349948
TI  - Effects of cycloheximide on the response of intestinal mucosa to cholera
      enterotoxin.
AB  - Prior studies have indicated that effects of cholera enterotoxin (CT) on the
      small intestine are delayed in onset and involve an interaction with adenyl
      cyclase in the mucosa. It has also been shown that the administration of
      cycloheximide to rabbits in doses which inhibit crypt cell mitoses (20 mg/kg),
      diminishes CT-induced fluid production in jejunal loops. These latter studies
      have been interpreted as indications that CT-related intestinal secretion is a
      crypt cell function and that it is mediated by a CT-induced protein. The present
      study was undertaken to delineate more precisely the nature of the interaction in
      the intestine between cycloheximide and cholera toxin. Pretreatment of rabbits
      with cycloheximide reduced by 60% the secretory response to CT in isolated ileal
      loops with intact blood supply. Sodium and chloride flux measurements on mucosa
      isolated from these and control loops indicated that this antisecretory effect of
      cycloheximide persists in vitro. Measurements of radioactive leucine
      incorporation into mucosal protein indicated that the dose of cycloheximide
      employed inhibited protein synthesis by 90%. This inhibitory effect was shown to
      be independent of any effect of cycloheximide on amino acid uptake across the
      brush border. Measurements of adenyl cyclase activity and cyclic AMP levels in
      ileal mucosa of cycloheximide pretreated and control animals indicated that
      cycloheximide did not diminish the CT-induced increases in these parameters.
      These observations demonstrate that cycloheximide reduces CT-induced intestinal
      fluid production without interfering with the CT-induced augmentation of adenyl
      cyclase activity or the consequent rise in cyclic. AMP concentration. Since the
      antisecretory effect of cycloheximide persists in vitro, it probably involves a
      direct interaction of the antibiotic with mucosal cell ion transport mechanisms
      rather than an indirect effect mediated by other humoral or neurogenic factors.
      The present observations also suggest that the secretory response of the
      intestine to CT involves neither the synthesis of new adenyl cyclase nor that of
      a protein modifying its activity.

PMID- 4349951
TI  - Effect of oestrogen upon parturition, maternal behaviour and lactation in
      ovariectomized pregnant rats.

PMID- 4349950
TI  - The interconversion of oestrone and oestradiol-17  and the concentration of
      oestradiol-17  receptors in cultured rabbit uterus.

PMID- 4349952
TI  - The relationship of the splanchnic, hepatic and renal clearance rates to the
      metabolic clearance rate of cortisol in conscious sheep.

PMID- 4349953
TI  - The role of transcortin in the regulation of corticotrophin secretion.

PMID- 4349954
TI  - Morphological differentiation of adrenal cortical cells induced by a 40-minute
      exposure to corticotrophin.

PMID- 4349956
TI  - [Malignant tumors of the nasal fossae].

PMID- 4349955
TI  - Effect of adrenocorticotrophin on 21- and 11 -hydroxylase activity in the
      biosynthesis of cortisol.

PMID- 4349957
TI  - The innervation of the juxtaglomerular apparatus and surrounding tubules: a
      quantitative analysis by serial section electron microscopy.

PMID- 4349958
TI  - Ultrastructural features of cellular maturation and aging in human trophoblast.

PMID- 4349959
TI  - [Evidence for the evolution of a phytolysosomal system in various parts of the
      cells of the radical nodules of the pea (Pisum sativum L.). Elementary
      heterophagy].

PMID- 4349960
TI  - Association between endoplasmic reticulum and vacuoles in frozen-etched root
      tips.

PMID- 4349961
TI  - [Diagnosis and differential diagnosis of bile duct adenomas (microhemartomas) of
      the liver].

PMID- 4349962
TI  - Effect of organic phosphates on the magnetic susceptibility of human
      deoxyhaemoglobin.

PMID- 4349963
TI  - Tripeptide in human serum which prolongs survival of normal liver cells and
      stimulates growth in neoplastic liver.

PMID- 4349964
TI  - The role of the community nurse concerned with after-care.

PMID- 4349965
TI  - [The virulence of dysenteric amebae for laboratory rats irradiated with different
      doses of Roentgen rays].

PMID- 4349966
TI  - [Etiology and prophylaxis of central nervous system injuries developing in fetal
      life].

PMID- 4349967
TI  - Serum total corticoid and cortisol levels in premature infants with respiratory
      distress syndrome.

PMID- 4349969
TI  - Silica urolithiasis in dogs fed an atherogenic diet.

PMID- 4349968
TI  - Corticoids and respiratory distress.

PMID- 4349970
TI  - Antiviral immune hemolysis.

PMID- 4349971
TI  - Interferon induction by rhinoviruses and effect of interferon on rhinovirus
      yields in human cell lines.

PMID- 4349973
TI  - The cytotoxic effect of human immune sera on Herpesvirus hominis infected cells.

PMID- 4349972
TI  - Uranyl nitrate induced acute renal failure in the rat: effect of varying doses
      and saline loading.

PMID- 4349974
TI  - Collagenase activity in tissues of selenium responsive myopathic lambs.

PMID- 4349975
TI  - Effect of adrenal arterial infusion of different Mg 2+  concentrations on the
      spontaneous release of catecholamines in the anesthetized dog.

PMID- 4349977
TI  - Angiotensins lung converting enzyme.

PMID- 4349976
TI  - Ovarian weight changes in immature female rats as a function of dose and exposure
      time to PMS.

PMID- 4349978
TI  - Differentiation of nephrotensin from angiotensin I and II.

PMID- 4349979
TI  - An artifact resembling silver grains found in microautoradiography of lettuce
      fruits.

PMID- 4349980
TI  - [Stimulating effect of the adrenocorticotrophic hormone on human blood
      lymphocytes in cell cultures].

PMID- 4349981
TI  - Partial mastectomy for carcinoma of the breast.

PMID- 4349982
TI  - Subcutaneous glomus tumors.

PMID- 4349983
TI  - A comparison of the treatment of gas gangrene with and without hyperbaric oxygen.

PMID- 4349984
TI  - Comparative study of experimental Clostridium perfringens infection in dogs
      treated with antibiotics, surgery, and hyperbaric oxygen.

PMID- 4349985
TI  - Scanning electron microscopy of erythrocytes adsorbed by ribonucleic acid virus
      infected cells in vitro.

PMID- 4349987
TI  - C-type virus particles in avian bursa of Fabricius cells grown in vitro.

PMID- 4349986
TI  - Naturally occurring infection of calves with a bovine adenovirus.

PMID- 4349989
TI  - Some current concepts of the pneumoconioses.

PMID- 4349990
TI  - [Glomus tumor with aggressive local behavior].

PMID- 4349988
TI  - Distribution of thyroid, parathyroid, and ultimobranchial hypocalcemic factors in
      birds. II. Morphology, histochemistry, and hypocalcemic activity of pigeon
      thyroid glands.

PMID- 4349991
TI  - Kinetic and electrophoretic abnormality of cyclic AMP phosphodiesterase in
      genetically obese mouse adipocytes.

PMID- 4349992
TI  - Effects of progesterone on the binding of estradiol-receptor to rabbit uterine
      chromatin.

PMID- 4349993
TI  - Reactive lysine residues in horse liver alcohol dehydrogenase.

PMID- 4349994
TI  - Topography of nucleic acid helices in solutions. 28. Evidence for a dynamic
      structure of DNA in solution.

PMID- 4349995
TI  - Inhibitor of adenosine 3',5'-monophosphate binding and protein kinase activity in
      leucocyte lysosomes.

PMID- 4349996
TI  - Lack of influence of mitochondrial genetical information on the multiplication of
      Herpes simplex virus in HeLa cells.

PMID- 4349997
TI  - Resonance Raman scattering on the haem group of cytochrome c.

PMID- 4349998
TI  - The presence of  -mannosidic linkage in acidic glycopeptide from porcine
      thyroglobulin.

PMID- 4349999
TI  - Two-dimensional polyacrylamide gel electrophoresis of acid extractable nuclear
      proteins of normal rat liver and Novikoff hepatoma ascites cells.

PMID- 4350000
TI  - Differences in the metabolism of phospholipids depending on cell population
      density.

PMID- 4350001
TI  - Effect of ribosomal protein L12 upon initiation factor IF-2 activities.

PMID- 4350002
TI  - Assembly and secretion of very low density lipoproteins by rat liver following
      inhibition of protein synthesis with cycloheximide.

PMID- 4350004
TI  - Foot-and-mouth disease circulating antibodies in convalescent cattle.

PMID- 4350003
TI  - Colchicine-induced inhibition of very low density lipoprotein release by rat
      liver in vivo.

PMID- 4350005
TI  - [Trivalent vaccine against foot-and-mouth disease of swine. Industrial and
      zootechnical aspect].

PMID- 4350006
TI  - Pathogenesis of foot-and-mouth disease in experimentally infected pigs.

PMID- 4350007
TI  - [Identification of epizootic strains of foot-and-mouth disease virus in the
      U.S.S.R].

PMID- 4350008
TI  - [Antigenic properties of strains of A 22  foot-and-mouth disease virus isolated
      in epizootic conditions].

PMID- 4350009
TI  - [Changes in antigen properties of foot-and-mouth disease virus during several
      passages].

PMID- 4350010
TI  - [Foot-and-mouth disease virus titration using the Color-test technic on IBR'S2
      line cells].

PMID- 4350011
TI  - [Hypertrophy of the corneal nerves in a case of bilateral congenital corneal
      opacity].

PMID- 4350012
TI  - Methanesulfonates: the relationship of structure to antitumor activity.

PMID- 4350014
TI  - Ventilatory effects of aerosolized kanamycin and polymyxin.

PMID- 4350013
TI  - Effect of compounds on a spectrum of rat tumors.

PMID- 4350016
TI  - Rapid method for screening for galactosemia and galactokinase deficiency by
      measuring galactose in whole blood spotted on paper.

PMID- 4350015
TI  - Granular cell myoblastoma of trachea associated with pregnancy.

PMID- 4350017
TI  - Stability of erythrocytic enzymes for screening tests.

PMID- 4350019
TI  - A genically determined abnormality in the number and arrangement of basal bodies
      in a ciliate.

PMID- 4350018
TI  - Effects of a partially purified factor from chick embryos on macromolecular
      synthesis of embryonic pancreatic epithelia.

PMID- 4350020
TI  - Decreased formation of syncytial plaques in the XC-test with a double-cloned
      hypotetraploid XC-cell line and evidence of budding C-type particles in this and
      ordinary hypodiploid XC-cell lines.

PMID- 4350022
TI  - Diffusion of pyrimethamine from silicone rubber and flexible epoxy drug capsules.

PMID- 4350021
TI  - A method of recording nerve terminal activity in the frog.

PMID- 4350024
TI  - Brief communication: specific transplantation antigens of murine neoplasms
      induced by visna and progressive pneumonia viruses.

PMID- 4350023
TI  - Alteration of immunocompetence by mammary tumor virus.

PMID- 4350025
TI  - Question: do herpesviruses cause cancer? Answer: of course they do.

PMID- 4350026
TI  - L-asparaginase-induced alterations of Burkitt's lymphoma cells.

PMID- 4350028
TI  - Inhibition of growth and transformation of human cells by interferon.

PMID- 4350027
TI  - Isolation of plasma membrane antigens from Epstein-Barr virus-infected lymphoid
      cells.

PMID- 4350029
TI  - Ultrastructural and complement-fixation studies on suspension cultures derived
      from human solid tumors.

PMID- 4350030
TI  - Induction of tumors in the liver of hamsters by an avian adenovirus (CELO).

PMID- 4350031
TI  - Mouse strain-related differences in the biologic and immunologic responses to a
      murine sarcoma virus.

PMID- 4350032
TI  - Lipid composition of Quaking mouse myelin: comparison with normal mouse myelin in
      the adult and during development.

PMID- 4350034
TI  - Serum glucose-6-phosphatase levels in normal pregnancy.

PMID- 4350033
TI  - GABA transport by nerve ending fractions of cat brain.

PMID- 4350035
TI  - A case of genital herpesvirus infection in pregnancy.

PMID- 4350036
TI  - Schistosome motility measurements: response to drugs.

PMID- 4350037
TI  - Cyclic adenosine monophosphate antagonism of morphine analgesia.

PMID- 4350038
TI  - Effects of cyclic 3',5'-adenosine monophosphate on morphine tolerance and
      physical dependence.

PMID- 4350039
TI  - Characterization of the adrenergic receptors mediating a rise in cyclic 3'-5'
      adenosine monophosphate in rat cerebral cortex.

PMID- 4350040
TI  - Study of phosphodiesterase inhibitors on lipolysis, phosphodiesterase activity
      and cyclic 3',5'-adenosine monophosphate levels in isolated fat cells.

PMID- 4350042
TI  - Intravenously given conjugated estrogens. Lack of effect of capillary stability.

PMID- 4350041
TI  - A possible etiology of contractility impairment of vascular smooth muscle from
      spontaneously hypertensive rats.

PMID- 4350043
TI  - Vitamin D: a reawakening.

PMID- 4350044
TI  - [Antalgic effect of cobamamide in the course of peripheral neuropathies of
      different etiopathogenesis].

PMID- 4350045
TI  - The effect of variations in LET and cell cycle on radiation hepatocarcinogenesis.

PMID- 4350046
TI  - [Changes of hepatic glycogen, lactic acid, glucose-6-phosphatase activity and
      succinate dehydrogenase in the sourse of tumor development under the influence of
      B thymus extract].

PMID- 4350047
TI  - [Action of myocardial peptide preparation on ovarian function in mice].

PMID- 4350048
TI  - [Enzyme-histochemical studies following a transversal section of the spinal
      cord].

PMID- 4350049
TI  - A qualitative and quantitative analysis of cuneate and gracile nuclei and of the
      dorsal column fibres.

PMID- 4350050
TI  - [Histochemical studies of the activity of various phosphatases and fructose-1,6
      diphosphate aldolase in the juxtaglomerular apparatus of rat kidney].

PMID- 4350051
TI  - [Enzyme histochemistry of the growing placenta in cattle].

PMID- 4350052
TI  - [Drug-induced lipidosis. IV. Morphological aspect of leukocytes and bone marrow
      cells in human cases and animal experiments induced by 4,4'-diethylaminoethoxy
      hexestrol].

PMID- 4350053
TI  - The sleep polygram: a potentially useful tool for clinical assessment in human
      infants.

PMID- 4350055
TI  - Fetal renal hamartoma--a benign tumor to be distinguished from Wilms' tumor.
      Report of 3 cases.

PMID- 4350054
TI  - On the significance of curvilinear bodies in late infantile lipidosis.

PMID- 4350056
TI  - Reduction of the tetrazolium salts in cells and tissue sections incubated without
      substrate.

PMID- 4350057
TI  - [Caustic burns of the esophagus in African children].

PMID- 4350058
TI  - Endometriosis of the bowel: role of bowel resection, superficial excision and
      oophorectomy in treatment.

PMID- 4350060
TI  - Diphosphoglycerate mutase and 2,3-diphosphoglycerate phosphatase activities of
      red cells: comparative electrophoretic study.

PMID- 4350059
TI  - Significance of postoperative estrogen therapy on the occurrence and clinical
      course of cancer.

PMID- 4350061
TI  - On the regulation of cyclic 3',5' adenosine monophosphate levels in bacteria.
      Stimulation of adenyl cyclase activity in vitro by glucose in a mutant of E. coli
      B-r.

PMID- 4350062
TI  - pH profiles of proline transport with membrane vesicles from Mycobacterium phlei
      with artificial and natural electron donors.

PMID- 4350063
TI  - Electron paramagnetic resonance of single crystal deoxycobaltohemoglobin.

PMID- 4350064
TI  - The detection of a bound ferredoxin in the photosynthetic lamellae of blue-green
      algae and other oxygen evolving photosynthetic organisms.

PMID- 4350065
TI  - Chain non-equivalence in nitric oxide binding to hemoglobin.

PMID- 4350066
TI  - Differences in the physical properties of collagenases isolated from rheumatoid
      synovium and human skin.

PMID- 4350067
TI  - Ion and pH gradients across the transport membrane of mitochondria following Mn
      ++  uptake in the presence of acetate.

PMID- 4350068
TI  - Site of impairment of oxidative phosphorylation in irradiated rats.

PMID- 4350069
TI  - Studies on the accessibility barrier of NADH to cytochromes b in pigeon-heart
      mitochondria.

PMID- 4350070
TI  - [The influence of various proton donors on the redox properties of ubiquinone-6
      in organic medium].

PMID- 4350071
TI  - Studies on electron transport associated with photosystem I. I. Functional site
      of plastocyanin: inhibitory effects of HgCl 2  on electron transport and
      plastocyanin in chloroplasts.

PMID- 4350072
TI  - The use of ketamine hydrochloride anaesthesia for radiotherapy in young children.

PMID- 4350074
TI  - Prevalence of deformities and disabilities among leprosy patients in an endemic
      area. II. Nerve involvement in the limbs.

PMID- 4350075
TI  - Fat mobilizing lipase in relation to fatness in lambs.

PMID- 4350076
TI  - Effects of methallibure on early pregnancy in swine.

PMID- 4350078
TI  - Corticosteroidogenesis in isolated adrenal cells: effect of adrenocorticotrophic
      hormone, adenosine 3',5'-monophosphate and   1-24  adrenocorticotrophic hormone
      diazotized to polyacrylamide.

PMID- 4350079
TI  - The zona glomerulosa and corticotrophin: a genetic study in mice.

PMID- 4350077
TI  - Interference of some pesticides in the milk phosphatase pasteurization test.

PMID- 4350080
TI  - Regulation of the permeability to water in toad urinary bladder: the effect of
      copper.

PMID- 4350082
TI  - Promotion of pituitary prolactin release in rats by dibutyryl adenosine 3',5'
      monophosphate.

PMID- 4350083
TI  - The conversion of angiotensin I to angiotensin II by rabbit glomeruli.

PMID- 4350081
TI  - A comparison of the effects of pituitary hormones and aminophylline on
      progestational hormone production by the rabbit ovary in vivo.

PMID- 4350084
TI  - Adrenal and testicular contribution to plasma oestrogens.

PMID- 4350085
TI  - Quantitative study on RNA metabolism in mononucleate and Sendai virus-induced
      multinucleate cells.

PMID- 4350086
TI  - Sleep and activity in a psychotic depression.

PMID- 4350087
TI  - Multiple pulmonary metastases from adenoid cystic carcinoma of ceruminous glands
      of external auditory canal. A case report and review of the literature.

PMID- 4350088
TI  - [Alpha feto protein or fetuin and its value in human biology].

PMID- 4350089
TI  - [Current studies on the role of lysosomes in the liberation of thyroid hormones].

PMID- 4350090
TI  - [Influencing of Parkinson's syndrome via intervention in the dopamine
      metabolism].

PMID- 4350091
TI  - [X-ray treatment of postoperative recurrences of malignant salivary gland
      neoplasms].

PMID- 4350092
TI  - [Dematoses and pregnancy].

PMID- 4350093
TI  - [Polygraphic study of nocturnal sleep in Parkinsonian syndromes. Effects of
      treatment levo-dopa].

PMID- 4350095
TI  - [Interactions in the avian oncornavirus group].

PMID- 4350094
TI  - [Optimal irradiation planning in deep  60 Co-therapy. Deliberations on the
      focusing technic in kidney malighomas].

PMID- 4350096
TI  - [Genetic analysis of animal viruses. II. Results. Prospects].

PMID- 4350097
TI  - [Ship drinking water disinfection using UV irradiation. II].

PMID- 4350098
TI  - Cholestyramine: factors limiting its antidiarrheal effect in patients resected
      for regional enteritis.

PMID- 4350099
TI  - Surgical treatment of amebic  liver abscess. Surgical treatment of hepatic 
      amebiasis.

PMID- 4350100
TI  - Calcifying mucinous adenocarcinoma of the gallbladder.

PMID- 4350101
TI  - Aortic mitochondrial function in experimentally induced atherosclerosis in swine
      and rabbits.

PMID- 4350102
TI  - Interaction of a spin-labeled analog of acetyl coenzyme A with citrate synthase.
      Paramagnetic resonance and proton relaxation rate studies of binary and ternary
      complexes.

PMID- 4350104
TI  - Chemistry of the adenosine monophosphate site of rabbit muscle glycogen
      phosphorylase. II. Properties of 8-(m-(m-gluorosulfonylbenzamido)
      benzylthio)adenine-modified phosphorylase.

PMID- 4350103
TI  - Effect of insulin and growth hormone on rat liver cyclic nucleotide
      phosphodiesterase.

PMID- 4350105
TI  - Dilatometry biological membranes.

PMID- 4350106
TI  - Structure of the lipid phase in cell envelope vesicles from Halobacterium
      cutirubrum.

PMID- 4350107
TI  - Composition and structure of the O-specific side chain of endotoxin from Serratia
      marcescens 08.

PMID- 4350108
TI  - Nuclear double-stranded ribonucleic acid of mammalian cells. Characteristics and
      biosynthesis.

PMID- 4350109
TI  - A marker for medullary carcinoma of thyroid.

PMID- 4350110
TI  - Prospective study of cytomegalovirus infection in pregnancy.
AB  - In a prospective study of cytomegalovirus infection in 1,040 pregnant women in
      London 319 (42%) of the white Englishwomen but only 28 (10%) of the immigrant
      Asian women were without antibodies at the onset of pregnancy. Out of 254
      susceptible white women and 16 susceptible Asian women 8 (3%) and 3 (16%)
      respectively experienced primary infection during the course of pregnancy. The
      overall incidence of fetal infection after primary infection in the mother was
      almost 50%, and was higher in early pregnancy. One out of the five infected
      infants was found to be mentally retarded.Reactivation of latent infection was
      recognized in 0.7-2.9% of pregnant women; this occurred without involving the
      fetus.

PMID- 4350111
TI  - Sarcoma after injection of intramuscular iron.
AB  - Two cases are presented of sarcomata arising at the site of previous iron dextran
      injections. One of the tumours showed a histological pattern associated with iron
      dextran administration in animal experiments.

PMID- 4350112
TI  - Serum alkaline phosphatase and rickets.

PMID- 4350114
TI  - Care of the patient with inoperable lung cancer.

PMID- 4350115
TI  - Dream recall: facts and perspectives.

PMID- 4350113
TI  - Immunological destruction in vitro of cytomegalovirus infected cells.

PMID- 4350116
TI  - [RNA-dependent RNA-polymerase in virions of Rous sarcoma virus].

PMID- 4350117
TI  - [Mechanism of the antineoplastic action of the inhibitor of free radical
      processes 2,6-di-tert-butyl-4-methylphenol (ionol)].

PMID- 4350118
TI  - [Possibilities of protraction of murine viral hepatitis. An experimental study].

PMID- 4350120
TI  - Consumer participation in mental health programs.

PMID- 4350119
TI  - Critical issues in psychiatry: a call for a reassessment of our nation's mental
      health care.

PMID- 4350122
TI  - Counteractions of the blocking of cell-mediated tumor immunity by inoculation of
      unblocking sera and splenectomy: immunotherapeutic effects on primary polyoma
      tumors in rats.

PMID- 4350121
TI  - Action of miracil D and related compounds on DNA and RNA synthesis in
      regenerating liver and hepatomas.

PMID- 4350123
TI  - Antibodies to EB virus capsid antigen and to soluble antigen of lymphoblastoid
      cells in infectious mononucleosis patients.

PMID- 4350124
TI  - Purification of antibodies to membrane antigens of hamster cells transformed by
      SV40 and binding of the radioiodinated, purified antibodies to intact cells.

PMID- 4350126
TI  - SV40-induced transformation of cells of the lizard Gekko gecko.

PMID- 4350125
TI  - Genetic stability of the sarcoma viruses in murine and avian sarcoma virus
      transformed nonproducer cells.

PMID- 4350127
TI  - Effects of SV40 virus on the chromosomes of poikilothermic cells (Gekko gecko)
      cultivated at different temperatures.

PMID- 4350128
TI  - [Study on the oncogenicity of U.V. irradiated SV40 for syrian hamster].

PMID- 4350129
TI  - Radioimmunoassay of carcinoembryonic antigen in extracts of human colon and
      stomach.

PMID- 4350130
TI  - The inducible alkaline phosphatase of rat heart: partial purification of the
      enzyme and its substrate specificity.

PMID- 4350131
TI  - [Thoracic pain observed at the pain clinic].

PMID- 4350132
TI  - [Kaliopenic endocrine diseases].

PMID- 4350134
TI  - Study of the ability of a DNA polymerase mutant E. coli K12 pol A1 for
      elimination of single-stranded breaks in DNA caused by methyl methanesulfonate.

PMID- 4350133
TI  - Plasma cortisol during normal glucose tolerance.

PMID- 4350135
TI  - Investigation of the mechanism of spectral changes in carotenoids in the
      chromatophores of Rhodospirillum rubrum.

PMID- 4350136
TI  - Study of the interaction of  -glycerophosphate dehydrogenase and NAD-H by the
      methods of circular dichroism and fluorimetry.

PMID- 4350137
TI  - Nature of the changes in the protein fluorescence of the mitochondria during a
      change in their functional state.

PMID- 4350139
TI  - Hepatoma originated in the retroperitoneal space. Report of a case.

PMID- 4350138
TI  - Biosynthesis of collagen in a chick embryo cell-free microsomal system.

PMID- 4350141
TI  - Mixed tumors of the lower lip.

PMID- 4350140
TI  - Fructose-1,6-diphosphatase in DMBA-induced rat mammary tumours.

PMID- 4350142
TI  - Correlations between mood, weight, and electrolytes during the menstrual cycle: a
      renin-angiotensin-aldosterone hypothesis of premenstrual tension.

PMID- 4350143
TI  - Biochemical effects of 1,1-dichloroethylene in rats: dissociation of its
      hepatotoxicity from a lipoperoxidative mechanism.

PMID- 4350144
TI  - Primary gastric neoplasia in the dog: a clinico-pathological study.

PMID- 4350145
TI  - [Changes in nerve cell ultrastructure in hypoxia].

PMID- 4350146
TI  - [Blood phospholipids in psychoses].

PMID- 4350147
TI  - The regeneration of skeletal muscle. A review.

PMID- 4350148
TI  - Biological effects of Corynebacterium parvum. IV. Adjuvant and inhibitory
      activities on B lymphocytes.

PMID- 4350149
TI  - Gradient gel electrophoresis of human plasma lipoproteins.

PMID- 4350150
TI  - A common error in measurements of 340 nm.

PMID- 4350152
TI  - [The effect of vagotomy on the impulse activity of the respiratory neurons].

PMID- 4350153
TI  - [The effect of extirpation of the thymus on adrenal cortical function].

PMID- 4350151
TI  - [Diagnosis and therapy of tumors and pseudotumors of the temporomandibular
      joint].

PMID- 4350154
TI  - Oestrogen and oestrogen conjugate concentrations in late pregnancy plasma.

PMID- 4350155
TI  - The specificity of the estrogen receptor of human uterus.

PMID- 4350157
TI  - [Streptozotocin in hormone-active metastasizing islet-cell carcinoma].

PMID- 4350156
TI  - Testosterone "receptors" in purified nuclei of rat anterior hypophysis.

PMID- 4350158
TI  - [Physiopathology of hypoglycemia in the newborn].

PMID- 4350159
TI  - [Plasma kininases in acute pneumonia in young children].

PMID- 4350161
TI  - Vasospasm in ischemic heart disease--a hypothesis.

PMID- 4350160
TI  - [Outbreaks of adenovirus infections among the newborn].

PMID- 4350162
TI  - [The effect of monovalent cations on the inhibition of the phosphorylated form of
      brain Na + , K + -ATPase by ouabain].

PMID- 4350163
TI  - [The content and metabolism of separate phospholipid fractions in the rat brain
      in insulin hypoglycemia and electrical skin stimulation].

PMID- 4350164
TI  - [Comparative evaluation of the acylphosphatase activity of various muscles].

PMID- 4350166
TI  - [Aldolase and  -glycerolphosphate and 3-phosphoglycerol aldehyde dehydrogenase
      activity of rabbit muscles in experimental atherosclerosis].

PMID- 4350165
TI  - [The effect of the dystrophic process on phospholipid metabolism in the
      myocardium].

PMID- 4350167
TI  - [Cytochemical determination of phosphodiesterase localizaton in blood and bone
      marrow cells].

PMID- 4350168
TI  - [Benign liver cholangioma. Apropos of a case of cholangiomatosis with
      laparoscopic and vascular studies].

PMID- 4350169
TI  - [The effect of low temperatures on the ultrastructure of brown fat tissue cells].

PMID- 4350170
TI  - Contrasting effects of plastocyanin on the photoreduction and photooxidation of
      cytochrome f in chloroplasts.

PMID- 4350171
TI  - In vitro studies on yeast cytochrome c peroxidase and its possible function in
      the electron transfer and energy coupling reactions.

PMID- 4350173
TI  - Electron transfer in cytochrome c: role of the polypeptide chain.

PMID- 4350172
TI  - Nitrogenase. 3. Nitrogenaseless mutants of Azotobacter vinelandii: activities,
      cross-reactions and EPR spectra.

PMID- 4350174
TI  - Nature of the activation of succinate dehydrogenase by various effectors and in
      hypobaria and hypoxia.

PMID- 4350175
TI  - Oxidative phosphorylation in mitochondria isolated from human fibroblasts.

PMID- 4350176
TI  - Freeze-fracture studies on mitochondria from wild-type and respiratory-deficient
      yeasts.

PMID- 4350177
TI  - [The cellular biology of the exocrine pancreas].

PMID- 4350178
TI  - Pigmented skin tumors.

PMID- 4350180
TI  - Sodium retention versus renin-angiotensin system in experimental renal
      hypertension.

PMID- 4350179
TI  - Effect of adrenocorticotropin (ACTH) upon the drug response of intact and
      adrenalectomized rats.

PMID- 4350181
TI  - Electron microscopy in the diagnosis of pleural mesotheliomas.

PMID- 4350182
TI  - Histology and ultrastructure of an oncocytic adenoma of the human pituitary.

PMID- 4350183
TI  - Pathogenesis of Hodgkin's disease: separation and culture of different kinds of
      cells from Hodgkin's disease in a sterile isokinetic gradient of Ficoll in tissue
      culture medium.

PMID- 4350185
TI  - Posterior hypothalamus and the regulation of body temperature.

PMID- 4350184
TI  - Addison's disease secondary to metastatic carcinoma: an example of adrenocortical
      and adrenomedullary insuffiency.

PMID- 4350186
TI  - Embryonic antigen expression in chemically induced rat hepatomas and sarcomas.

PMID- 4350188
TI  - The transformation of BHK 21 hamster cells by simian virus 40.

PMID- 4350187
TI  - Carcinoembryonic antigen (CEA) in gastrointestinal and extragastrointestinal
      tumors and its relationship to tumor-cell differentiation.

PMID- 4350189
TI  - Variations in sarcoma and leukemia virus activity in somatic cell hybrids.

PMID- 4350190
TI  - Australia antigen in Singapore Chinese patients with hepatocellular carcinoma and
      comparison groups: influence of technique sensitivity on differential
      frequencies.

PMID- 4350191
TI  - The SV40 S antigen; a carcinoembryonic-type antigen of the hamster?

PMID- 4350192
TI  - Human cancer in households containing cats with malignant lymphoma.

PMID- 4350193
TI  - Feline malignant lymphoma: environmental factors and the occurrence of this viral
      cancer in cats.

PMID- 4350194
TI  - Dietary aspects of hyperlipidemia.

PMID- 4350195
TI  - Effect of certain biologic and antibacterial agents on development of acute
      respiratory tract disease in weaned beef calves.

PMID- 4350196
TI  - Chemical studies on tuberactinomycin. 3. The chemical structure of viomycin
      (tuberactinomycin B).

PMID- 4350197
TI  - Relationships between antimicrobial activities and chemically reactive functions
      in viomycin.

PMID- 4350198
TI  - Cyclic AMP phosphodiesterase activity in the midgut of Manduca sexta.

PMID- 4350199
TI  - Effects of dietary manipulation on adipose tissue glycerokinase activity and
      plasma metabolite levels in the chicken (Gallus domesticus).

PMID- 4350201
TI  - Single unit responses in the neospinothalamic system of the cat.

PMID- 4350200
TI  - Effects of blunted sympathetic nervous system response on regional tissue
      perfusion in experimental endotoxic shock.

PMID- 4350202
TI  - Parasitization of the parasite.

PMID- 4350203
TI  - [The enzyme histochemistry of Ammon's horn in white rats].

PMID- 4350204
TI  - [Study of intramitochondrial inclusions by enzyme digestion].

PMID- 4350205
TI  - Central control of movement. VI. Strategies and tactics in research on central
      control of movement.

PMID- 4350206
TI  - Central control of movement. IV. Control systems operating on spinal reflex
      mechanisms.

PMID- 4350208
TI  - [Anatomoclinical considerations on several cases of nephroblastoma in children].

PMID- 4350207
TI  - [Anti-lipoprotein and anti-emulsive activity of monoclonal IgM. "A series of
      specific anti-emulsive antibodies"].

PMID- 4350209
TI  - [Care after cure of leg ulcer: a phlebology lesson for the bandagery].

PMID- 4350210
TI  - Cranio-orbital resection and neck dissection for a recurrent mixed tumor of the
      lacrimal gland. Case report.

PMID- 4350211
TI  - [Virilizing adrenal tumor with a borderline increase in urinary 17-ketosteroid
      levels].

PMID- 4350212
TI  - [Clinical and polygraphic study of a case of Kleine-Levin Critchley syndrome
      during a 24-hour period].

PMID- 4350213
TI  - Actomyosin-like protein in brain.

PMID- 4350214
TI  - Epstein-Barr virus: detection of genome in somatic cell hybrids of Burkitt
      lymphoblastoid cells.
AB  - Somatic cell hybrids of Burkitt lymphoblastoid cells, from which Epstein-Barr
      virus can be recovered, were examined for the presence of virus DNA by DNA-RNA
      hybridization. Four clones of hybrid cells, each negative for virus antigens by
      immunofluorescence, contained virus DNA in varying genomic equivalents. The
      number of virus genome equivalents increased in the hybrid cells after induction
      of virus with iododeoxyuridine.

PMID- 4350215
TI  - The metabolism in vivo 4,16-androstadien-3-one in man. Occurrence of 16-dehydro C
      19  steroids, androstane-3,16,17-triols and other metabolites in urine.

PMID- 4350216
TI  - Isolation and identification of 16alpha, 18-dihydroxydeoxycorticosterone from
      human adrenal gland incubations.

PMID- 4350217
TI  - The occurrence and subcellular localization of 3 -hydroxysteroid dehydrogenase in
      adult rat brain.

PMID- 4350218
TI  - [Role of cortical-subcortical interrelations in the mechanism of auditory
      adaptation].

PMID- 4350219
TI  - Adenovirus type 12 surface antigen detected by immunofluorescence in infected KB
      cells.

PMID- 4350221
TI  - Interaction of genes controlling resistance to RSV(RAV-O).

PMID- 4350220
TI  - Transcriptive functions of Sendai firus nucleocapsid in infected cells.

PMID- 4350222
TI  - Properties of an SV40 transformed African green monkey kidney (BSC-1) cell line:
      interactions between SV40 and cellular DNA metabolism.

PMID- 4350223
TI  - The identification of the circular forms of SV40 DNA in whole infected cell
      preparations.

PMID- 4350225
TI  - Effect of actinomycin D on potato virus X multiplication in Datura stramonium
      leaves.

PMID- 4350224
TI  - Effects of 2-deoxy-D-glucose on herpes simplex virus replication.

PMID- 4350226
TI  - Isolation of the structural polypeptides of foot-and-mouth disease virus and
      analysis of their C-terminal sequences.

PMID- 4350227
TI  - A temperature-sensitive mutant of simian virus 40 affecting transforming ability.

PMID- 4350228
TI  - Genetic recombinants and heterozygotes derived from endogenous and exogenous
      avian RNA tumor viruses.

PMID- 4350229
TI  - Incorporation of 5-iodo-2'-deoxyuridine (IUdR) into SV40 DNA.

PMID- 4350230
TI  - Control of group-specific antigen synthesis by the defective Gazdar murine
      sarcoma virus genome.

PMID- 4350232
TI  - Base specific methylase activity in RNA tumor viruses: avian leukosis virion
      associated RNA methylase(s).

PMID- 4350231
TI  - Iodination of vesicular stomatitis virus with lactoperoxidase.

PMID- 4350233
TI  - [Comparative observations of the level of antibodies to respiratory syncytial
      virus and parainfluenza virus type 3 in children at a children's home].

PMID- 4350234
TI  - [The use of the immunofluorescence method for detecting specific membrane antigen
      induced by Rous virus in different classes of animals].

PMID- 4350235
TI  - [Study of the pathways of intrauterine transmission of the herpes simplex virus
      in an experiment on rabbits].

PMID- 4350236
TI  - [Study of that portion of the population of Leningrad that is immune to
      cytomegalovirus].

PMID- 4350237
TI  - [The ultrastructure of RK-13 cells infected by rubella virus].

PMID- 4350238
TI  - [Serological control of the state of immunity in children inoculated with live
      poliomyelitis vaccine].

PMID- 4350239
TI  - [Study of the effectiveness of the action of polyvinylpyrrolidone, polyvinyl
      alcohol and their combinations with interferon in various manifestations of
      herpetic infection].

PMID- 4350240
TI  - [Study of the interfering activity of the Vnukovo-32 vaccinal strain of the
      rabies virus].

PMID- 4350241
TI  - [A second immunological test for detecting minimal amounts of OV40 monkey virus].

PMID- 4350242
TI  - [Study of the viral flora in viral hepatitis patients].

PMID- 4350243
TI  - [Interferonogenic activity and sensitivity of rhinoviruses to interferon].

PMID- 4350244
TI  - Laboratory calibration of a technique for determination of respirable quartz in
      mine air.

PMID- 4350246
TI  - An oxygen magnetic resonance study of water in frog skeletal muscle.

PMID- 4350245
TI  - Cooperative onset of a different state of water in the presence of
      macromolecules.

PMID- 4350247
TI  - Supramolecular biology: a solid state physical approach to ion and electron
      transport.

PMID- 4350248
TI  - Implications of diffusion coefficient measurements for the structure of cellular
      water.

PMID- 4350249
TI  - The diffusion of water in striated muscle.

PMID- 4350250
TI  - The effect of GTP hydrolysis by the peptide elongation enzymes on the
      sedimentation of ribosomes bearing peptidyl-tRNA and on the susceptibility of
      ribosome-bound tRNA to hydrolysis by  ribonuclease.

PMID- 4350252
TI  - Effect of substrate on the spin state of cytochrome P-450 in hepatic microsomes.

PMID- 4350251
TI  - The oxidation of N,N'-bis(4-aminophenyl)-N,N'-dimethylethylenediamine (BED) by
      rat liver.

PMID- 4350253
TI  - The inactivation of lactoperoxidase and the acyl phosphatase activity of oxidized
      glyceraldehyde-3-phosphate dehydrogenase by phenlyhydrazine and phenyldiimide.

PMID- 4350254
TI  - 31 P and  13 C nmr measurements of a fructose-1-phosphate, Mn (II) and fructose
      1,6-diphosphatase complex.

PMID- 4350255
TI  - Hippocampal EEG and behavior: changes in amplitude and frequency of RSA (theta
      rhythm) associated with spontaneous and learned movement patterns in rats and
      cats.

PMID- 4350256
TI  - Incremental and decremental processes in Limulus ganglia: stimulus frequency and
      ganglion organization influences.

PMID- 4350257
TI  - Circular dichroism of cytochrome oxidase, cytochrome b 566 , and cytochrome c in
      beef heart mitochondrial membrane fragments.

PMID- 4350258
TI  - Cytochrome oxidase from Pseudomonas aeruginosa. I. Reaction with copper protein.

PMID- 4350259
TI  - Iron protein content of Thiocapsapfennigii, a purple sulfur bacterium of atypical
      chlorophyll composition.

PMID- 4350260
TI  - Primary events in the photosynthetic reaction centre from Rhodopseudomonas
      spheroides strain R26: triplet and oxidized states of bacteriochlorophyll and the
      identification of the primary electron acceptor.

PMID- 4350261
TI  - A peroxide-dependent reduction of cytochrome c by NADH.

PMID- 4350262
TI  - Hydrogen peroxide generating system in hog thyroid microsomes.

PMID- 4350263
TI  - Studies on the metabolites of phylloquinone (vitamin K 1 ) in the urine of man.

PMID- 4350264
TI  - Adenylate cyclase activity in normal and leukemic human leukocytes as determined
      by a radioimmunoassay for cyclic AMP.

PMID- 4350265
TI  - Regulation of renal glycogen synthase. Interconversion of two forms in vitro.

PMID- 4350267
TI  - Occurrence of a galactofuranose disaccharide in immunoadjuvant fractions of
      Mycobacterium tuberculosis (Cell walls and wax D).

PMID- 4350266
TI  - Regulation of glycogen phosphorylase a phosphatase in Neurospora crassa.

PMID- 4350268
TI  - Adenosine 3':5'-monophosphate-dependent and independent histone kinases isolated
      from human tonsillar lymphocytes.

PMID- 4350270
TI  - Adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate: concentrations
      in Morris hepatomas of different growth rates.

PMID- 4350271
TI  - Firing patterns of Purkinje cells in the cat cerebellum for different maintained
      positions of the limbs.

PMID- 4350269
TI  - Inhibition of metabolic effects of growth hormone by various inhibitors of cyclic
      nucleotide phosphodiesterase.

PMID- 4350272
TI  - Temporal sequence of cerebellar Purkinje and nuclear activity in relation to the
      acoustic startle  response.

PMID- 4350273
TI  - Attempted suicide: a description of the pre and post suicidal states.

PMID- 4350274
TI  - Baroreceptor activity in normotensive and hypertensive uremic patients.

PMID- 4350275
TI  - Liberal telephone policy in treatment and aftercare helps reduce readmissions.

PMID- 4350276
TI  - Central response to infra-red stimulation of the pit receptors in a crotaline 
      snake, Trimeresurus flavoviridis.

PMID- 4350277
TI  - Integration of sensory and centrally programmed components in generation of
      cyclical feeding activity of Helisoma trivolvis.

PMID- 4350278
TI  - Color and spatial specificity of single units in Rhesus monkey foveal striate
      cortex.

PMID- 4350279
TI  - [Experimental approach to the pathogenesis of systemic lupus erythematosus].

PMID- 4350280
TI  - [Radiological measurement of compact bone thickness in children with generalized
      bone disease].

PMID- 4350281
TI  - Histamine and cyclic 3',5'-AMP in gastric acid secretion.

PMID- 4350282
TI  - Influence of cell-free ascites fluid and adenosine 3'5'-cyclic monophosphate upon
      the cell kinetics of Ehrlich's ascites carcinoma.

PMID- 4350283
TI  - Oestrogen receptor binding is not restricted to target nuclei.

PMID- 4350284
TI  - Epstein-Barr virus in human disease.

PMID- 4350285
TI  - Thrombosthenin, the contractile protein of blood platelets. New facts and
      problems.

PMID- 4350286
TI  - ESR study of a new anthraquinone glycoside.

PMID- 4350287
TI  - [Diabetes in patients treated surgically for pancreatic carcinoma].

PMID- 4350288
TI  - Psychiatry, through mental health to human services--what next?

PMID- 4350289
TI  - The planned obsolescence of psychiatric research.

PMID- 4350290
TI  - Cellular biochemistry of narcotic analgesic drugs in the central nervous system
      of the rat.

PMID- 4350291
TI  - [Poisoning by a fungicide, hexachlorbenzene, contaminating wheat grains].

PMID- 4350292
TI  - [Method for appraisal and measurement of extrapyramidal symptoms and signs.
      Clinical evaluation of Parkinsonism. Value in the evaluation of severeness, in
      the estimation of the evolutive potential, in the appreciation as strict as
      possible of the effectiveness of antiparkinson therapy].

PMID- 4350293
TI  - [Is the glucoamylasemic test useful in clinical medicine? I. Hydrotherapy at
      Vichy and the glucoamylasemic test].

PMID- 4350294
TI  - [Is the glucoamylase test useful in clinical medicine? II. Critical study of the
      glucoamylasemic test].

PMID- 4350296
TI  - Effect of cortisol on neuraminic acid concentration of normal and polyoma
      transformed mouse cells in culture.

PMID- 4350295
TI  - [Porphyria cutanea tarda. (Apropos of 2 cases associated with cancer of the
      liver)].

PMID- 4350297
TI  - Bovine herpes mammillitis virus and vulvo-vaginitis.

PMID- 4350298
TI  - [Results using ciclacillin with special reference to tolerance and adverse
      effects].

PMID- 4350299
TI  - [Secretion of growth hormone and insulin in patients with acromegaly].

PMID- 4350300
TI  - [Lupus type tubular inclusions in malignant melanoma].

PMID- 4350301
TI  - In vivo effect of adenosine 3',5'-monophosphate on Ehrlich ascites tumour cells.

PMID- 4350302
TI  - Endocrine control of fetal lung development in the rabbit.

PMID- 4350303
TI  - Neurologic complications following lymphangiography. Possible mechanisms and a
      case of blindness.

PMID- 4350304
TI  - Reticular units: relations between responses to sensory stimulation and responses
      to neurohumors.

PMID- 4350305
TI  - Pupillary inhibition of delay during Pavlovian conditioning of paralyzed cats.

PMID- 4350306
TI  - 4'-Thioadenosine 3'5'-cyclic phosphate and derivatives. Chemical synthesis and
      hydrolysis by phosphodiesterase.

PMID- 4350307
TI  - Biosynthesis of glutamate dehydrogenase in rat liver. Demonstration of its
      microsomal localization and hypothetical mechanism of transfer to mitochondria.

PMID- 4350309
TI  - The mechanism of polymyxin B action and selectivity toward biologic membranes.

PMID- 4350308
TI  - The lactate dehydrogenase catalyzed reduction of pyruvate. Active substrate and
      substrate inhibition.

PMID- 4350310
TI  - Isolation and partial chemical characterization of cell-surface glycopeptides
      from AS-30D rat hepatoma which possess binding sites for wheat germ agglutinin
      and concanavalin A.

PMID- 4350311
TI  - Estrogen receptors in the rat uterus. Relationship between cytoplasmic and
      nuclear forms of the estrogen binding protein.

PMID- 4350312
TI  - [Free radicals characteristic of thymidine 5'-phosphate photosensitized by
      proflavine].

PMID- 4350313
TI  - Reaction of diethyl pyrocarbonate with nucleic acid components. Adenosine
      containing nucleotides and dinucleoside phosphates.

PMID- 4350314
TI  - Role of silicon in diatom metabolism. II. Endogenous nucleoside triphosphate
      pools during silicic acid starvation of synchronized Cylindrotheca fusiformis.

PMID- 4350315
TI  - Role of silicon in diatom metabolism. 3. The effects of silicic acid on DNA
      polymerase, TMP kinase and DNA synthesis in Cylindrotheca fusiformis.

PMID- 4350316
TI  - Fractionation of denatured bacterial DNA on methylate albumin kieselguhr columns.
      Is it strand separation?

PMID- 4350317
TI  - The discharge from primary endings of muscle spindles during reflex activation of
      fusimotor neurones in the lightly anaesthetised and spinal cat.

PMID- 4350318
TI  - Spinal and medullary reflex components of the somatosympathetic reflex discharges
      evoked by stimulation of the group IV somatic afferents.

PMID- 4350319
TI  - The adenosine 3',5'-monophosphate content of brain tissue obtained by an ultra
      rapid freezing technique.

PMID- 4350320
TI  - Synaptic delay: its effect on information transmission in the crayfish caudal
      photoreceptor system.

PMID- 4350321
TI  - Development of binocular single units in the optic tectum of frogs raised with
      disparate stimulation to the eyes.

PMID- 4350322
TI  - Excitatory and inhibitory inputs to single neurones in the solitary tract nucleus
      and adjacent reticular formation.

PMID- 4350323
TI  - Sleep patterns related to rearing rats in enriched and impoverished environments.

PMID- 4350324
TI  - Effects of chlorpromazine on sleep in cats pretreated with para
      chlorophenylalanine.

PMID- 4350326
TI  - Unit responses recorded from cervical spinal cord of awake monkey.

PMID- 4350325
TI  - Responses of red nucleus neurones to cutaneous afferent inputs.

PMID- 4350328
TI  - The joint peristimulus-time scatter diagram is an index of the operational
      significance of a synapse.

PMID- 4350329
TI  - Action of penicillin on inhibitory processes in the cat's cortex.

PMID- 4350327
TI  - Habituation of the flexor reflex: inhibitory build-up or synaptic depression?

PMID- 4350330
TI  - Convulsant actions of penicillin: effects on inhibitory mechanisms.

PMID- 4350331
TI  - Metastatic mammary carcinoma in the eyelid with histiocytoid appearance.

PMID- 4350332
TI  - Lateral inhibition in ambylopia: VER and metacontrast.

PMID- 4350333
TI  - Centrifugal effects on the cat electroretinogram after section of one optic
      nerve.

PMID- 4350334
TI  - [Calcification of the adrenal gland and cytomegalovirus infection in early
      childhood].

PMID- 4350336
TI  - Personal styles of program implementors: a case study in community mental health
      failure.

PMID- 4350335
TI  - [Uniform theory on the etiology and development of somatic, psychosomatic and
      mental diseases].

PMID- 4350337
TI  - Will success spoil mental health care?

PMID- 4350339
TI  - The synovitis of acute gouty arthritis. A light and electron microscopic study.

PMID- 4350338
TI  - Pathology of the adventitial dermis. Anatomic observations and biologic
      speculations.

PMID- 4350340
TI  - Florid subareolar duct papillomatosis (nipple adenoma) and mammary carcinoma:
      report of three cases.

PMID- 4350341
TI  - Interference and two-tone inhibition.

PMID- 4350343
TI  - Stimulation by cyclic adenosine monophosphate of plasmid deoxyribonucleic acid
      replication and catabolite repression of the plasmid deoxyribonucleic acid
      protein relaxation complex.
AB  - Colicinogenic factors ColE1 and ColE2 are bacterial plasmids that exist in
      Escherichia coli as supercoiled deoxyribonucleic acid (DNA) and as strand
      specific, relaxation complexes of supercoiled DNA and protein. Newly replicated
      ColE1 DNA becomes complexed with protein after the replication event. This
      association of DNA and protein can take place under conditions in which DNA or
      protein synthesis is arrested. The addition of cyclic adenosine monophosphate (c
      AMP) to normal cells growing in glucose medium results in a six- to tenfold
      stimulation in the rate of synthesis of the protein component(s) of the complex
      and a three- to fivefold stimulation in the rate of ColE1 DNA replication.
      Employing mutants deficient in catabolite gene activator protein or adenylate
      cyclase, it was shown that synthesis of both the plasmid-determined protein
      colicin E1 and the protein component(s) of the ColE1 relaxation complex is
      mediated through the c-AMP-catabolite gene activator protein system. Addition of
      c-AMP to ColE2-containing cells results in the stimulation of synthesis of ColE2
      DNA and relaxation protein(s) as well as in the production of a protein component
      of the ColE2 relaxation complex that renders it sensitive to induced relaxation
      by heat treatment. In the case of ColE2, synthesis of the relaxation protein(s)
      is not dependent upon catabolite gene activator protein.

PMID- 4350342
TI  - Characterization of a cold-sensitive hisW mutant of Salmonella typhimurium.
AB  - A cold-sensitive mutant of Salmonella typhimurium LT2 that grows at 37 C but not
      at 20 C has altered repression regulation in at least two amino acid biosynthetic
      pathways (histidine and isoleucine). The lesion conferring cold sensitivity that
      is linked with hisW is recessive. Assays for the acceptance of some amino acids
      by transfer ribonucleic acid (tRNA) reveal a decreased ability of the mutant tRNA
      to accept arginine, phenylalanine, and histidine. A mutation in a gene for tRNA
      maturation is a likely possibility for the mutation producing these effects on
      growth, regulation, and amino acid acceptance.

PMID- 4350344
TI  - Cyclic adenosine monophosphate-independent mutants of the lactose operon of
      Escherichia coli.
AB  - In Escherichia coli the transcription of the lactose operon, like other
      catabolite-sensitive operons, requires catabolite gene activator protein and
      3',5'-cyclic adenosine monophosphate in addition to ribonucleic acid polymerase.
      We isolated and analyzed lac(+) revertants from a crp(-) strain of E. coli. We
      found that revertants with a higher level of expression only for the lac operon
      lie in the lac promoter region. These promoter mutations have no effect on
      operator or repressor function. Two of the revertants in which the lesions have
      been more precisely mapped carry mutations in the operator proximal segment of
      the promoter.

PMID- 4350346
TI  - [Statistical study (500 cases of ano-rectal cancers). Therapeutic indications.
      Long-term results].

PMID- 4350345
TI  - A paracrystalline inclusion formed during sporulation of enterotoxin-producing
      strains of Clostridium perfringens type A.
AB  - A large paracrystalline inclusion is formed by certain strains of Clostridium
      perfringens type A during spore morphogenesis. In most cell thin sections, the
      inclusion appeared rod-shaped when sectioned at an angle perpendicular to its
      longer axis, and circular or oval-shaped when sectioned at an angle parallel to
      its longer axis. Measurements performed on electron micrographs of inclusions
      sectioned to reveal the rod shape indicated a fairly consistent thickness (width)
      of 192 +/- 23 nm. The length of the inclusions varied considerably with a maximum
      of approximately 2,120 nm being observed. Ultrastructurally, the inclusion was
      composed of closely packed, periodically spaced, parallel layers. Usually a
      single inclusion was randomly located in the cytoplasm of the cell. Two
      inclusions per cell were rarely observed. The inclusion was formed only by ent(+)
      strains of C. perfringens. Mutants of the ent(+) strain NCTC 8798 that were
      altered in their sporulating and enterotoxin-producing capacities and revertants
      of these mutants were tested for inclusion formation. The results indicate that,
      as with the ent(+) trait, a direct relationship exists between inclusion
      formation and spore formation. The synthesis of enterotoxin, formation of a
      morphologically distinct inclusion, and the initial deposition of discontinuous
      coat fragments around the forespore appear to be events closely related in time
      during spore morphogenesis.

PMID- 4350347
TI  - [Primary cancers of the liver (P.C.L.). Basis for therapeutic indications.
      Results. Classification].

PMID- 4350348
TI  - ACTH and cortisol secretory patterns in man.

PMID- 4350349
TI  - Chorionic gonadotropin sensitive adenylate cyclase in human term placenta.

PMID- 4350350
TI  - Studies on calciferol metabolism. VII. The renal production of the biologically
      active form of vitamin D, 1,25-dihydroxycholecalciferol; species, tissue and
      subcellular distribution.

PMID- 4350351
TI  - Endemic goiter prevention by iodized oil: a reassessment.

PMID- 4350352
TI  - Differential effect of cyclic adenosine monophosphate on the secretion of human
      placental lactogen and human chorionic gonadotropin.

PMID- 4350353
TI  - The ascending fiber projections from the principal sensory trigeminal nucleus in
      the rat.

PMID- 4350354
TI  - Reciprocal point-to-point connections between parastriate and striate cortex in
      the squirrel monkey (Saimiri).

PMID- 4350355
TI  - Injection of ACTH induces recovery from shuttle-box avoidance deficits in rats
      with amygdaloid lesions.

PMID- 4350356
TI  - Correlations of neuronal spike discharges produced by monosynaptic connections
      and by common inputs.

PMID- 4350357
TI  - Changes in polarization of central branches of myelinated mechanoreceptor and
      nociceptor fibers during noxious and innocuous stimulation of the skin.

PMID- 4350358
TI  - Convergence of cutaneous and preoptic region thermal afferents on posterior
      hypothalamic neurons.

PMID- 4350359
TI  - Distributed neuronal oscillators and efference copy in the feeding system of
      Pleurobranchaea.

PMID- 4350360
TI  - Peripheral somatic activation of neurons in the cat red nucleus.

PMID- 4350361
TI  - Physiology of vision in the mollusk Lima scabra.

PMID- 4350362
TI  - [Physical training in the home following myocardial infarct--the Hamburg model].

PMID- 4350363
TI  - [Experimental induction of obesity in animals].

PMID- 4350365
TI  - Electrical transmission between symmetrical neurons in leech ganglia.

PMID- 4350364
TI  - Cerebellar unit responses to repetitive stimulation of somatic nerves.

PMID- 4350366
TI  - On the use of psychiatric diagnosis for comparing psychiatric populations.

PMID- 4350367
TI  - Evaluation of community psychiatric practice.

PMID- 4350368
TI  - Virus-induced transformation without cell division.
AB  - Interference with the cell cycle by vinblastine sulfate immediately after cells
      were infected with Rous sarcoma virus had little effect on the a development of
      two metabolic changes that occur in transformed cells. These results, along with
      an earlier demonstration of morphological changes developing in infected
      nondividing cells, demonstrate that the phenotypic development of the malignant
      state can occur without the intervention of cell divisions after infection by
      Rous sarcoma virus.

PMID- 4350369
TI  - [Effect of oral administration of L-dopa on plasma levels of TSH, ACTH and GH in
      normal subjects].

PMID- 4350370
TI  - [Paralytic syndrome of the 4 limbs during neurogenic hypernatremia].

PMID- 4350371
TI  - [Application of cytochemical methods to 47 cases of acute leukemia. Cytochemical
      chages during development].

PMID- 4350373
TI  - [Late enteromesenteric metastasis of a tumor of the granulosa].

PMID- 4350372
TI  - [Paradoxical menstruation and resistant ascites due to granulosa cell tumor in
      postmenopause. Value of the cytogenetic study of the ascitic fluid].

PMID- 4350374
TI  - [Immunofluorescence in clinical and laboratory studies on Herpes simplex virus].

PMID- 4350375
TI  - [E-B virus infection and its relationship to infectious mononucleosis].

PMID- 4350376
TI  - [Laboratory diagnosis of congenital cytomegalovirus infections].

PMID- 4350377
TI  - [Cytomegalic inclusion disease in mice. Lesions produced in the generalized
      form].

PMID- 4350378
TI  - [Distribution of some dehydrogenases in macroglial type tumors].

PMID- 4350379
TI  - [Radiological method for determining linear and volumetric blood flow in organic
      lesions of the brain].

PMID- 4350380
TI  - An evaluation of immunological indicators for amebic disease prevalence.

PMID- 4350381
TI  - [Histoenzymologic study of cirrhosis provoked by carbon tetrachloride in rats].

PMID- 4350382
TI  - [Cylindromatous adenocardinoma of the breast].

PMID- 4350383
TI  - Mucinous (adenocystic) carcinoma of the eyelid.

PMID- 4350384
TI  - Studies of SV 40 DNA. V. Conversion of circular to linear SV 40 DNA by
      restriction endonuclease from Escherichia coli B.

PMID- 4350385
TI  - The identification of different structural classes of nucleic acids by
      electrophoresis in polyacrylamide gels of different concentration.

PMID- 4350386
TI  - In vivo and in vitro effects of thyrotropin on ribosomal pattern of dog thyroid.

PMID- 4350388
TI  - Biosynthesis of mitochondrial enzymes.

PMID- 4350387
TI  - The primary electron acceptor of photosystem. I.

PMID- 4350389
TI  - Lipoproteins in relation to skin disease.

PMID- 4350390
TI  - Conversion of angiotensin I into angiotensin II in the isolated perfused rat
      kidney.

PMID- 4350391
TI  - Structure of normal and pathological lipoproteins.

PMID- 4350392
TI  - Beta lipoprotein protein turnover: an approach to the understanding of drug and
      disease mechanisms.

PMID- 4350393
TI  - Carbohydrate metabolism of larval Schistosoma mansoni.

PMID- 4350394
TI  - The intranuclear bodies of Entamoeba.

PMID- 4350395
TI  - The surface active lysosome of Entamoeba histolytica.

PMID- 4350396
TI  - Action of prostaglandin E 2  and of luteinizing hormone on ovarian adenylate
      cyclase, protein kinase and ornithine decarboxylase activity during postnatal
      development and maturity in the rat.

PMID- 4350397
TI  - The estimation of human renin-substrate concentration by radioimmunoassay of
      angiotensin I.

PMID- 4350398
TI  - Steroid hormones and their receptors.

PMID- 4350400
TI  - Subcutaneous growth of human tumours in mice.

PMID- 4350399
TI  - The regulation of intestinal calcium transport by vitamin D.

PMID- 4350401
TI  - [Alpha foetoprotein].

PMID- 4350402
TI  - [Survival of poliovirus in stools of poliomyelitis patients following various
      storage periods].

PMID- 4350403
TI  - Macrophage nonimmunologic recognition: target cell factors related to contact
      inhibition.
AB  - Activated mouse macrophages were not cytotoxic to contact-inhibited
      nontumorigenic 3T3 fibroblasts, but caused marked destruction to non-contact
      inhibited, tumorigenic 3T12 and simian virus 40-transformed fibroblasts.
      Nonimmunologic recognition and destruction of target cells by activated
      macrophages is independent of altered morphology, abnormal karyotype, and ability
      for continuous multiplication in vitro-all characteristics of 3T3 fibroblasts. A
      modification e f the target cell surface that results in a high in vitro
      saturation density, agglutinability by plant lectins, and tumorigenicity appears
      to evoke a cytotoxic response by activated macrophages.

PMID- 4350404
TI  - Thyrotropin and cyclic nucleotide effects on prostaglandin levels in isolated
      thyroid cells.
AB  - Thyrotropin increases prostaglandin levels in isolated thyroid cells. Since
      comparable results were obtained with butyrated cyclic adenosine monophosphate
      derivatives as well as with the phosphodiesterase inhibitors quazodine and
      theophylline, it appears that cyclic adenosine monophosphate mediates this effect
      of thyrotropin. These observations suggest that intracellular prostaglandins play
      a role in modulating thyrotropin action on thyroid.

PMID- 4350405
TI  - Radioreceptor assay for prolactin and other lactogenic hormones.
AB  - A radioreceptor assay with a sensitivity of 5 nanograms per milliliter has been
      developed for mammalian and avian pituitary prolactin, placental lactogenic
      hormones, and humnan growth hormone, using a membrane receptor preparation
      isolated from rabbit mammary glands. Prolactin preparations inhibited the binding
      of [(125)I]prolactin to receptors in direct proportion to the biological potency
      of these preparations. Thus, the radioreceptor assay provides a convenient and
      simnple assay for hormones which have lactogenic activity.

PMID- 4350406
TI  - Effects of deep-sea pressures on microbial enzyme systems.

PMID- 4350407
TI  - [Fluorometric determination of enolase, pyruvate kinase and lactate dehydrogenase
      activity in individual isolated nerve cells].

PMID- 4350409
TI  - Morphometry of dog liver: normal base-line data.

PMID- 4350408
TI  - Chlorphentermine-induced ultrastructural alterations in foetal tissues.

PMID- 4350410
TI  - Genesis of foam cells: study in rats after administration of Cloforex.

PMID- 4350411
TI  - Participation of monocytes in transient glomerular hypercellularity in
      poststreptococcal glomerulonephritis.

PMID- 4350412
TI  - In vitro assembly of polioviruses. 3. Assembly of 14 S particles into empty
      capsids by poliovirus-infected HeLa cell membranes.

PMID- 4350413
TI  - HeLa cell nucleolar RNA synthesis after poliovirus infection.

PMID- 4350414
TI  - Temperature-sensitive avian sarcoma viruses: a physiological comparison of twenty
      mutants.

PMID- 4350415
TI  - Integration of viral into chromosomal deoxyribonucleic acid in an inducible line
      of polyoma-transformed cells.

PMID- 4350417
TI  - Measurement of endogenous leukosis virus nucleotide sequences in the DNA of
      normal avian embryos by RNA-DNA hybridization.

PMID- 4350416
TI  - Appearance of virus-specific RNA, virus particles, and cell surface changes in
      cells rapidly transformed by the murine sarcoma virus.

PMID- 4350418
TI  - Comparison of oligonucleotides produced by RNase T1 digestion of 7 S RNA from
      avian and murine oncornaviruses and from uninfected cells.

PMID- 4350419
TI  - On neural inhibition, contrast effects and visual sensitivity.

PMID- 4350420
TI  - Chemodectoma with distant metastasis: case report and review of the literature.

PMID- 4350422
TI  - Experimental study of interactions between pneumoconiosis and mycobacterial
      infections.

PMID- 4350421
TI  - The other side of marihuana research.

PMID- 4350423
TI  - The role of quartz in the development of coal workers' pneumoconiosis.

PMID- 4350424
TI  - Inhalation studies of coal-quartz dust mixture.

PMID- 4350425
TI  - The pulmonary response to coal dust.

PMID- 4350426
TI  - Antagonistic factors in the pathogenesis of coal workers' pneumoconiosis.

PMID- 4350427
TI  - Prevalence of coal workers' pneumoconiosis in Yugoslavia.

PMID- 4350428
TI  - Coal workers' pneumoconiosis in South Africa.

PMID- 4350429
TI  - Factors influencing dust retention in the pulmonary parenchyma.

PMID- 4350430
TI  - Types of fibrosis in coal workers' pneumoconiosis.

PMID- 4350431
TI  - Relation of lung dust content to radiological changes in coal workers.

PMID- 4350432
TI  - Roentgen pathological correlations in coal workers' pneumoconiosis.

PMID- 4350433
TI  - Validation of classifications of pneumoconiosis.

PMID- 4350434
TI  - Treatment of pneumoconiosis caused by coal-quartz dusts with polyvinylpyridine-N
      oxide (P 204).

PMID- 4350435
TI  - Sampling and evaluating respirable coal mine dust.

PMID- 4350436
TI  - Perspectives in current research for control of airborne dust in coal mines.

PMID- 4350437
TI  - Recent advances in the analysis of respirable coal dust for free silica, trace
      elements, and organic constituents.

PMID- 4350438
TI  - Investigative techniques in the laboratory study of coal workers' pneumoconiosis:
      recent advances at the cellular level.

PMID- 4350439
TI  - [Hypocalcemic pseudo-deficient vitamin resistant rickets].

PMID- 4350440
TI  - The physiology of renin.

PMID- 4350442
TI  - Glomus jugulare tumours--radiotherapy or surgery?

PMID- 4350441
TI  - Liver-cell carcinoma presenting as bile-duct tumour.

PMID- 4350443
TI  - Multiple renal silica calculi.
AB  - Investigation of a patient with a history of renal colic, who had taken the
      equivalent of 2 g magnesium trisilicate after every meal for many years, showed
      that he was forming silica calculi. The nature of the stone was diagnosed only
      after quantitative analysis.

PMID- 4350444
TI  - The denatured states of lysozyme.

PMID- 4350445
TI  - Comparative study of the development of alkaline phosphodiesterase I and alkaline
      phosphatase in mucosa of rat jejunum and ileum.

PMID- 4350446
TI  - Studies on glycogen metabolism in normal and diabetic rat heart in vivo.

PMID- 4350447
TI  - Thymidine as one of the factors in a beef liver extract decreasing  3 H-thymidine
      incorporation into DNA.

PMID- 4350448
TI  - Ribonucleic acid polymerase induced in L-cells infected with vesicular stomatitis
      virus.

PMID- 4350449
TI  - [Pathomorphology and treatment of macrodactyly].

PMID- 4350450
TI  - Let us stay near our patients.

PMID- 4350451
TI  - [Malignancy of the middle lobe syndrome].

PMID- 4350452
TI  - [Bronchial carcinoma. A retrospective study on 2200 patients].

PMID- 4350453
TI  - Ultrastructural and biochemical changes in the liver of monkeys given butylated
      hydroxytoluene and butylated hydroxyanisole.

PMID- 4350454
TI  - Relative eye-injury potential of heavy-duty phosphate and non-phosphate laundry
      detergents.

PMID- 4350455
TI  - Hypophysis and function of pancreatic islets. 3. Secretion and biosynthesis of
      insulin in isolated pancreatic islets of intact and hypophysectomized rats in the
      presence of growth hormone, corticotrophin and human chorionic somatotrophin in
      vitro.

PMID- 4350456
TI  - Fasting in obese females: plasma renin after glucose refeeding.

PMID- 4350458
TI  - ACTH inhibition of dehydration-induced changes in the hypothalamic neurosecretory
      system of the musk shrew, suncus murinus L.

PMID- 4350457
TI  - Thyroid hormone binding to the anterior pituitary gland.

PMID- 4350459
TI  - Sero-epidemiology of cytomegalovirus infection in and around Chandigarh (Northern
      India).

PMID- 4350460
TI  - The epidemiology of amoebiasis in an urban area.

PMID- 4350461
TI  - Direct amoebicidal action of known antiamoebic drugs against axenically grown
      Entamoeba histolytica.

PMID- 4350462
TI  - Adrenergic neurone blocking actions of procaine and lignocaine.

PMID- 4350463
TI  - [Exploration of glomus jugulare tumors by means of selective angiography of the
      external carotid with subtraction].

PMID- 4350464
TI  - [Gastric pseudotumors in infants].

PMID- 4350465
TI  - [Simplified determination of bone age from the surface of large bones].

PMID- 4350466
TI  - Nondysenteric intestinal amebiasis. Treatment with diloxanide furoate.

PMID- 4350467
TI  - Dibutyryl cyclic AMP and adrenaline increase contractile force and  45 Ca uptake
      in mammalian cardiac muscle.

PMID- 4350468
TI  - Effect of acute transection on the synthesis and turnover of 5-HT in the rat
      spinal cord.

PMID- 4350469
TI  - Non-competitive and competitive inhibition of mixed function oxidase in rat liver
      microsomes by metyrapone.

PMID- 4350472
TI  - Effects of stress and REM sleep deprivation on the patterns of avoidance learning
      and brain acetylcholine in the mouse.

PMID- 4350471
TI  - [Screening of anticytomegalovirus antibodies in the course of prenatal
      examination].

PMID- 4350470
TI  - Effects on shock-elicited aggression in mice of preferentially protecting brain
      monoamines against the depleting action of reserpine.

PMID- 4350473
TI  - Interaction of oxotremorine with atropine, chlorpromazine, cyproheptadine,
      imipramine and phenoxybenzamine on the flexor reflex of the chronic spinal dog.

PMID- 4350474
TI  - Enzyme release from polymorphonuclear leukocyte lysosomes: regulation by
      autonomic drugs and cyclic nucleotides.
AB  - Osmotic release of beta-glucuronidase from polymorphonuclear leukocyte lysosomes
      is inhibited by catecholamines and adenosine 3',5'-monophosphate, and accelerated
      by cholinergic agents and guanosine 3',5'-monophosphate. These actions are
      specific for the sympathetic and parasympathetic neurotransmitters and for the
      two cyclic nucleotides, as phenylephrine, tyramine, choline, adenosine 5'
      monophosphate and guanosine 5'-monophosphate do not inodify lysosomal enzyme
      release.

PMID- 4350475
TI  - [Oncogenic DNA viruses: the role of viral genes in cell transformation].

PMID- 4350476
TI  - [Viral gene expression in transformed cells].

PMID- 4350477
TI  - [Cell transformation by the EB herpetic virus].

PMID- 4350478
TI  - Endothelial inclusions in congenital infantile nephrosis.

PMID- 4350479
TI  - Cellular autophagy and cell atrophy in the rat liver during long-term starvation.
      A quantitative morphological study with regard to diurnal variations.

PMID- 4350480
TI  - The development of cholangiofibrosis and hepatomas in galactosamine induced
      cirrhotic rat livers.

PMID- 4350481
TI  - [Human phosphofructokinase isozymes].

PMID- 4350482
TI  - The primary structure of tRNA trp  from brewer's yeast. I. Complete digestion
      with pancreatic ribonuclease and T 1  ribonuclease.

PMID- 4350483
TI  - The primary structure of tryptophan transfer ribonucleic acid from brewer's
      yeast. II. Partial digestion with pancreatic ribonuclease and derivation of
      complete sequence.

PMID- 4350484
TI  - Accessibility of Escherichia coli 5S RNA base residues to chemical reagents.
      Influence of chemical alterations on the affinity of 5S RNA for the 50S subunit
      structure.

PMID- 4350485
TI  - In vivo studies of the possible role of cholesteryl esters as precursors of bile
      acids.

PMID- 4350486
TI  - [Analytical study of phospholipids from chicken erythrocytes].

PMID- 4350487
TI  - [Description of an electrophoretic technic for isolation of cyclic AMP from its
      metabolites. Application to adenylclyclase activity determination].

PMID- 4350488
TI  - Retinal embolism after hysterosalpingography.

PMID- 4350489
TI  - [Effect of cAMP and of regulator protein on the in vitro action of human
      chorionic gonadotropin (HCG) on the corpus luteum].

PMID- 4350490
TI  - [Localization of ribonucleic acids in a murine oncornavirus].

PMID- 4350491
TI  - [Study of the corticotropic secretion during compensatory hypertrophy of the
      adrenal gland].

PMID- 4350492
TI  - [Application of the occupation theory to renal receptors of lysine vasopressine
      coupled to adenylcyclase. Study using tritiated vasopressin].

PMID- 4350493
TI  - [Preliminary study of X-ray diffraction diagrams of different high humidity DNA
      fibers].

PMID- 4350494
TI  - [Viruses and interferon].

PMID- 4350495
TI  - [Myelopathies due to cervical stenosis and cervicarthrosis (apropos of 50 cases
      operated and reviewed with follow-up of 2 to 10 years].

PMID- 4350496
TI  - Ultrastructural observations on the calcification of human dental pulp.

PMID- 4350497
TI  - Scanning electron microscopic observations on bone from patients with
      hypophosphataemic (vitamin D resistant) rickets.

PMID- 4350498
TI  - The binding of pyrophosphate and two diphosphonates by hydroxyapatite crystals.

PMID- 4350500
TI  - The swinging flashlight test in multiphasic screening for eye disease.

PMID- 4350499
TI  - Factors affecting the precipitation of calcium phosphate in vitro.

PMID- 4350501
TI  - The effects of bacterial collagenase in rabbit vitreous.

PMID- 4350502
TI  - Preparation and specificity of antiserum to synthetic secretin and its use in a
      radioimmunoassay (RIA).

PMID- 4350503
TI  - Dissociation of gonadotropin-induced ovulation and steroidogenesis in immature
      rats.

PMID- 4350504
TI  - Incorporation of orthophosphate 32Pi into the phospholipids of slices of gonads,
      anterior pituitary and liver of calf.

PMID- 4350505
TI  - Characteristics of the nuclear RNA polymerase from rat anterior pituitary tissue.

PMID- 4350507
TI  - Compared action of a polyoma-virus-specific inhibitor on the formation of polyoma
      capsid antigen and of polyoma tumor antigen.

PMID- 4350508
TI  - Cellular reactions against Burkitt Lymphoma cells. I. Colony inhibition with
      effector cells from patients with Burkitt's lymphoma.

PMID- 4350506
TI  - Amoebiasis in pediatric age group.

PMID- 4350509
TI  - Spontaneous appearance of cytopathology and rat C-type virus (WF-1) in a rat
      embryo cell line.

PMID- 4350510
TI  - Studies on type-H virus-like particles in hamster: their role in oncogenesis.

PMID- 4350511
TI  - Cytomegalovirus infections in leukaemic children.

PMID- 4350512
TI  - [Delayed hypersensitivity reactions in patients bearing malignant brain tumors
      with human tumor cell lines grown in vitro].

PMID- 4350513
TI  - Cellular immunity in Wilm's tumour and neuroblastoma.

PMID- 4350514
TI  - The formation of variants with a reversion of properties of transformed cells.
      VII. Chromosome numbers and re-reversion in subtetraploid variants.

PMID- 4350515
TI  - Is the brain behind the eye? Implications of processing by the retina.

PMID- 4350516
TI  - [EM-autoradiographic studies on the inflammatory cells in the experimental
      Japanese encephalitis].

PMID- 4350517
TI  - A varicella-like disease in macaque monkeys.

PMID- 4350518
TI  - Host defense mechanisms against herpes simplex virus. II. Protection conferred by
      sensitized spleen cells.

PMID- 4350519
TI  - Failure to induce fetal infection by inoculation of pregnant immune heifers with
      bovine parainfluenza 3 virus.

PMID- 4350520
TI  - Spontaneous Herpesvirus saimiri lymphoma in an owl monkey.

PMID- 4350521
TI  - Incidence of antibody to envelope antigen of herpes simplex virus type 2 among
      patients with cervical carcinoma and matched controls.

PMID- 4350523
TI  - [Translienal hepatography with iophendylate].

PMID- 4350522
TI  - The effects of endogenous compounds on ovine myometrial contractility and adenyl
      cyclase system.

PMID- 4350524
TI  - [Role of entero- and adenoviruses in the etiology of appendicitis in children].

PMID- 4350525
TI  - [Morphofunctional changes in the endocrine system during hypoxia].

PMID- 4350526
TI  - [Phosphate metabolism].

PMID- 4350527
TI  - Transmission of rhinovirus colds by self-inoculation.

PMID- 4350528
TI  - Inapparent congenital cytomegalovirus infection. A follow-up study.

PMID- 4350529
TI  - Infant of the addicted mother.

PMID- 4350531
TI  - Congenital cytomegalovirus infection.

PMID- 4350530
TI  - Median-nerve neuropathy after percutaneous puncture of the brachial artery in
      patients receiving anticoagulants.

PMID- 4350533
TI  - [Disorders of interhemispheric transfer (callosal disonnection). 3 cases of tumor
      of the corpus callosum. The strange hand sign].

PMID- 4350532
TI  - Isolation of human amnion cells transformed by rescuable murine sarcoma virus.

PMID- 4350535
TI  - Studies on the fine structure of the protozoan Cyclidium, with special reference
      to the mitochondria, pellicle and surface-associated bacteria.

PMID- 4350534
TI  - [Biogenic amine mediators and proteinase activity in various sections of the rat
      brain during sleep and deprivation of its paradoxical phase].

PMID- 4350536
TI  - [Blood vessels of the basal plate of the human placenta at term. Light and
      electron microscopical studies].

PMID- 4350538
TI  - [Ultrastructure of the dorsal giant fibre system in the ventral nerve cord of the
      earthworm. II. Synaptic connections of the proximal collaterals of the giant
      fibres].

PMID- 4350537
TI  - [Ultrastructure of the dorsal giant fibre system in the ventral nerve cord of the
      earthworm. I. Somata of the giant fibres].

PMID- 4350539
TI  - The ultrastructure of the caecal epithelium of the intraredial cercaria of
      Neophasis lageniformis (Lebour, 1910) (Trematoda, Acanthocolpidae).

PMID- 4350540
TI  - The synaptic ribbons of the guinea-pig pineal gland under normal and experimental
      conditions.

PMID- 4350541
TI  - Arrhenoblastoma: in vivo and in vitro studies.

PMID- 4350542
TI  - Mortality, antibody development, and viral persistence in porcine fetuses
      incubated in utero with SMEDI (entero-) virus.

PMID- 4350543
TI  - Feline virus-induced tumors and the immune response: recent developments.

PMID- 4350544
TI  - Vaccination against Marek's disease: possible causes of failure of herpesvirus of
      turkeys (strain FC126) to protect chickens against Marek's disease.

PMID- 4350545
TI  - A simple method for obtaining undiluted nasal secretions from cattle.

PMID- 4350546
TI  - Abdominal-muscle rigidity induced by morphine and nitrous oxide.

PMID- 4350547
TI  - [Clinical, morphological and histogenetic problems concerning mixed tumours of
      the salivary glands].

PMID- 4350548
TI  - [Abrikossoff's tumor of the larynx. Apropos of a case].

PMID- 4350549
TI  - The mitotic apparatus of a zygomycete, Phycomyces blakesleeanus.

PMID- 4350550
TI  - Cell wall composition and synthesis via Golgi-directed scale formation in the
      marine eucaryote, Schizochytrium aggregatum, with a note on Thraustochytrium sp.

PMID- 4350551
TI  - Comparison of early injury to liver endoplasmic reticulum by halomethanes,
      hexachloroethane, benzene, toluene, bromobenzene, ethionine, thioacetamide and
      dimethylnitrosamine.

PMID- 4350552
TI  - Effect of cyclic 3',5'-monophosphate on edema and granuloma induced by
      carrageenin.

PMID- 4350553
TI  - Effect of protein deficiency on the inducibility of the hepatic microsomal drug
      metabolizng enzyme system. II. Effect of enzyme kinetics and electron transport
      system.

PMID- 4350554
TI  - Inhibition of some mitochondrial functions by acrolein and methylvinylketone.

PMID- 4350555
TI  - Inhibition by cysteamine of steroid 11  -hydroxylation.

PMID- 4350556
TI  - Importance of the route of administration of ccl 4 in the protective effect of
      promethazine.

PMID- 4350557
TI  - Magnetic resonance studies on membrane and model membrane systems. 3. Fatty acid
      motions in aqueous lecithin dispersions.

PMID- 4350558
TI  - Effect of proteins on the motion of spin-labeled fatty acids in mycoplasma
      membranes.

PMID- 4350560
TI  - Platelet dysfunction in glycogen storage disease type I.

PMID- 4350559
TI  - Preparation of plasma membranes from isolated cells of newborn rat brain.

PMID- 4350561
TI  - [Uterine metastasis from a colloid epithelioma of the appendix].

PMID- 4350563
TI  - [5 S estradiol receptor, acid protein of the nucleus and nucleoplasmic RNA
      polymerase in cow endometrium].

PMID- 4350564
TI  - [Secretion of insulin and glucagon by the pancreas in newborn rats: effect of
      glucose and 3'-5'cyclic AMP adensine monophosphate].

PMID- 4350562
TI  - [Case of ovarian thecoma].

PMID- 4350565
TI  - [Chemical structure of fibrinogen in modified chickens].

PMID- 4350566
TI  - [Existence of a nucleotide pyrophosphatase in germinated fenugreek seeds].

PMID- 4350567
TI  - Heterogeneity of acid phosphatase activity in human polymorphonuclear leukocytes.

PMID- 4350568
TI  - Neuroradiology of juxtasellar mass lesions.

PMID- 4350569
TI  - [Severe rachitic osteopathy during long-term anticonvulsant treatment].

PMID- 4350570
TI  - [Calcium metabolism disorders in antiepileptic therapy].

PMID- 4350571
TI  - [Oral contraceptives in excessive longitudinal growth].

PMID- 4350572
TI  - Communication for child mental health: 1973 NIMH information interchange.

PMID- 4350573
TI  - The fate of mestranol (17 -ethynylestradiol-3-methyl ether) in the isolated
      perfused rat liver.

PMID- 4350574
TI  - Effect of insulin on cerebral adenyl cyclase and phosphodiesterase.

PMID- 4350575
TI  - The influence of deamidation on the biological activity of porcine
      adrenocorticotropic hormone (ACTH).

PMID- 4350576
TI  - Inhibitors of proteolysis and glucose uptake by diaphragm muscle in vitro under
      insulin action.

PMID- 4350577
TI  - Further studies with precipitation in gel test in diagnosis of smallpox. I.
      Studies on detection of antibodies in sera by pig test.

PMID- 4350578
TI  - Aflatoxin hepatic carcinogenesis: an experimental comparative study.

PMID- 4350579
TI  - Comparative drug trials in symptomatic and asymptomatic non-dysenteric amoebic
      colitis.

PMID- 4350580
TI  - Minor salivary gland tumors: a survey of 64 cases.

PMID- 4350581
TI  - Malignant mixed tumor of parotid gland with a solitary metastasis to the radius.

PMID- 4350582
TI  - [Metabolism of blood platelets: biochemical aspects of its release reaction].

PMID- 4350583
TI  - [Reciprocal action of nonfunctional coenzyme binding sites in dehydrogenases with
      (nicotinamide-ribofuranosyl)-(omega-(adenine-9-yl)-n-alkyl)-pyrophosphates].

PMID- 4350584
TI  - [Detection of complement fixing antibodies against Herpes simplex virus (and
      other neurotropic viruses) in patients with multiple sclerosis].

PMID- 4350585
TI  - [Medical therapy of hyperadrenalism].

PMID- 4350586
TI  - [Cytomegalovirus disease in childhood. (Clinical and epidemiological
      considerations)].

PMID- 4350587
TI  - Aminoacyl-tRNA synthetase activity in virions of avian myeloblastosis virus.

PMID- 4350588
TI  - Transfer of the B77 virus genome from virogenic mammalian cells to other
      mammalian cells by cell fusion.

PMID- 4350589
TI  - Monoclonal macroglobulinemia and cytomegalic inclusion disease.

PMID- 4350590
TI  - Electron microscopic demonstration of adenovirus in appendix vermiformis in a
      case of ileocecal intussusception.

PMID- 4350591
TI  - Cancer of the colon and disseminated intravascular coagulation.

PMID- 4350592
TI  - A sensitive cell culture system for the virus of porcine inclusion body rhinitis
      (cytomegalic inclusion disease).

PMID- 4350593
TI  - Tests in sheep of attenuated sheep pox vaccines.

PMID- 4350594
TI  - Factors associated with the production of attenuated sheep pox vaccines.

PMID- 4350595
TI  - Antagonists of angiotensin. Effect on the blood pressure of normal and
      hypertensive rats.

PMID- 4350596
TI  - Presence and stimulation of adenyl cyclase in pancreas homogenate.

PMID- 4350597
TI  - [Effect of different antimetabolites on the lethal activity of colicin K on
      Escherichia coli K-12].

PMID- 4350598
TI  - [Does ACTH have a place in rheumatology?].

PMID- 4350599
TI  - [Acute hypercaldemic episodes due to parathyroid disorder].

PMID- 4350600
TI  - [Metastatic calcifications in primary hyperparathyroidism].

PMID- 4350601
TI  - [Secondary hyperparathyroidism in patients with chronic kidney failure].

PMID- 4350602
TI  - [Myelomonocytic leukemia and pulmonary alveolar proteinosis].

PMID- 4350603
TI  - [Emergency laparoscopy in the diagnosis of jaundice associated with acute kidney
      failure. Its value apropos of 25 cases].

PMID- 4350604
TI  - [Microcrystals and their cytopathogenic implication in arthritis].

PMID- 4350605
TI  - [Tumors and pseudo-tumoral diseases of the synovial membrane: classification and
      review of the literature].

PMID- 4350606
TI  - [Hly plasmid in R-plasmid carrying strains of Escherichia coli].

PMID- 4350607
TI  - Generalized cytomegalic inclusion disease presenting an infectious mononucleosis
      syndrome (so-called cytomegalovirus mononucleosis) in a previously healthy adult-
      an autopsy study.

PMID- 4350609
TI  - Pathological studies on viral pneumonia and interstitial pneumonitis caused by
      unknown etiology.

PMID- 4350608
TI  - Post-traumatic hypothalamic obesity--an autopsy case.

PMID- 4350611
TI  - Lipoproteins and the relative importance of plasma cholesterol and triglycerides
      in peripheral arterial disease.

PMID- 4350610
TI  - Role of the small intestine in cholesterol metabolism.

PMID- 4350612
TI  - Indetification and characterization of pulmonary dust burden in pneumoconiosis.

PMID- 4350614
TI  - CNS: afferent mechanisms with emphasis on physiological and behavioral
      correlations.

PMID- 4350613
TI  - Separation of plasma lipids by thin-layer chromatography.

PMID- 4350616
TI  - Hypothalamic control of adenohypophysial secretions.

PMID- 4350615
TI  - Biochemical physiology of central synapses.

PMID- 4350617
TI  - Repeated oral ingestion of 5-hydroxytryptophan. The effect on behavior and sleep
      processes in two schizophrenic children.

PMID- 4350618
TI  - Wakefulness and feeding in human newborns.

PMID- 4350619
TI  - [Ocular myopathy with mitochondrial abnormalities. Clinical and ultrastructural
      study].

PMID- 4350620
TI  - [Ultrastructure, histoenzymology and micro-angiotectonics of the human iris].

PMID- 4350622
TI  - Hexachlorobenzene and rat liver.

PMID- 4350621
TI  - Biochemical studies of liver tumors of children.

PMID- 4350624
TI  - Grouped muscle action potential area.

PMID- 4350623
TI  - Congenital mesoblastic nephroma and its recurrence.

PMID- 4350625
TI  - Peripheral nerve damage resulting from local hemorrhage and ischemia.

PMID- 4350627
TI  - Antibodies to viral and synthetic double-stranded RNA in discoid lupus
      erythematosus.

PMID- 4350626
TI  - Fine structural analysis of rabbit synovial cells. I. The normal synovium and
      changes in organ culture.

PMID- 4350628
TI  - [Effect of an unspecific stimulating drug on embryonic cells and tissues in
      vitro].

PMID- 4350629
TI  - Rat mammary gland nuclear RNA polymerases in late pregnancy and lactation.

PMID- 4350630
TI  - Interaction of 6-thioguanylic acid homologues with ribonuclease T 1 .
      Spectrophotometric and gel filtration studies.

PMID- 4350631
TI  - Degradation of ribosomal RNA during chicken lens development.

PMID- 4350632
TI  - [Glomangiomatosis].

PMID- 4350633
TI  - Lack of significant visible C-type virus activation in the bone marrow and thymus
      of mice given a leukaemogenic dose of methylnitrosourea.

PMID- 4350635
TI  - [Diagnostic significance of electromyography in nervous system diseases].

PMID- 4350634
TI  - [Clinical application of evoked potentials of the cerebrum].

PMID- 4350636
TI  - Tracheotomy in infants and children.

PMID- 4350637
TI  - [Change in the free radical content of body tissues due to the toxic effect of
      chemical compounds].

PMID- 4350638
TI  - [Role of the physico-biochemical uncoupling mechanism of bicameral synapses in
      the evolution of their rapid action].

PMID- 4350640
TI  - [Economical neural inhibition].

PMID- 4350639
TI  - [Myoneural conduction blockade by choline esters in the presence of
      cholinesterase inhibitors and restoration of conduction by cholinesterase
      reactivators].

PMID- 4350641
TI  - Effects of ethanol on afferent transmission in the central visual pathway of
      cats.

PMID- 4350642
TI  - Partial reduction of ferricytochrome c by cyanide mediated by disulphide
      compounds.

PMID- 4350643
TI  - Iron binding in human liver ferritin.

PMID- 4350644
TI  - Origin of the milk fat globule.

PMID- 4350645
TI  - The requirement of membrane sialic acid in the stimulation of phagocytosis by the
      natural tetrapeptide, tuftsin.

PMID- 4350646
TI  - Hormonal regulation of adipocyte enzymes. The effects of epinephrine and insulin
      on the control of lipase, phosphorylase kinase, phosphorylase, and glycogen
      synthase.

PMID- 4350647
TI  - The role of acidic phospholipids in glucagon action on rat liver adenylate
      cyclase.

PMID- 4350648
TI  - Glucocorticoid receptors in lung. I. Specific binding of glucocorticoids to
      cytoplasmic components of rabbit fetal lung.

PMID- 4350649
TI  - The enzymatic cleavage of 5'-triphosphate termini from ribonucleic acid
      polymerase products.

PMID- 4350650
TI  - The structure of oxidized cytochrome c 2  of Rhodospirillum rubrum.

PMID- 4350651
TI  - Complex formation between bacitracin peptides and isoprenyl pyrophosphates. The
      specificity of lipid-peptide interactions.

PMID- 4350653
TI  - Studies on rat liver phenylalanyl transfer ribonucleic acid synthetase. II.
      Further purification, substrate specificity, and effects of substrates on heat
      inactivation.

PMID- 4350652
TI  - Studies on enzymes involved in the catabolism of phospholipids in Escherichia
      coli.

PMID- 4350654
TI  - Purification and properties of Ascaris cytochrome b 560.

PMID- 4350655
TI  - Novel phosphoglucans from the cytoplasm of Phytophthora palmivora and their
      selective occurrence in certain life cycle stages.

PMID- 4350656
TI  - Leukocytic response to adrenocorticotrophic hormone as influenced by the
      infectious history of the mammary gland.

PMID- 4350657
TI  - Effects of stress on serum zinc and plasma corticoids in dairy cattle.

PMID- 4350658
TI  - Reduction of iodine transfer to milk of cows after perchlorate ingestion.

PMID- 4350660
TI  - Epidemiology of cancer of the pancreas.

PMID- 4350661
TI  - Correlation between tumor invasiveness and content of A-type particles in Ehrlich
      ascites tumor: a model of quantitative electron microscopy.

PMID- 4350659
TI  - Primary pulmonary neoplasms in beagle dogs exposed to aerosols of  144 Ce in
      fused-clay particles.

PMID- 4350662
TI  - Mammary tumor virus (MTV) infection of CBA/Bln mice involving production of
      antibodies to MTV.

PMID- 4350663
TI  - Spontaneous tumors of aging wild house mice. Incidence, pathology, and C-type
      virus expression.

PMID- 4350664
TI  - Histoproliferative effect of Rauscher leukemia virus on lymphatic tissue. IV.
      Lactic dehydrogenase virus and erythropoietin potentiation of the eythroid
      response.

PMID- 4350665
TI  - Increased oncogenicity and synthesis of herpesvirus antigens in hamster cells
      exposed to herpes simplex type-2 virus.

PMID- 4350666
TI  - Oncogenicity of plaque variants of CELO virus in newborn hamsters.

PMID- 4350667
TI  - Suppression of growth of P-815 mastocytoma cells in vitro by drugs increasing
      cellular cyclic 3',5'-adenosine monophosphate.

PMID- 4350668
TI  - Soluble and membrane-bound adenylate cyclase activity in Yoshida ascites
      hepatoma.

PMID- 4350669
TI  - Ketone body oxidation by mouse hepatoma BW7756.

PMID- 4350670
TI  - [Influence of room temperature of night-sleep].

PMID- 4350672
TI  - [Mechanism of the p-chlorophenylalanine (PCPA) inhibited pancreas secretion].

PMID- 4350671
TI  - [Importance of selective angiography of the external carotid with subtraction in
      the diagnosis of tumors of the jugular glomus. Apropos of 5 cases].

PMID- 4350673
TI  - [The cerebrospinal fluid lactate dehydrogenase isoenzymes of neuro-oncologic
      patients].

PMID- 4350674
TI  - [A study of lipid metabolism in multiple sclerosis].

PMID- 4350675
TI  - [Determination of 3-hydroxyacetylindole in rat tissues].

PMID- 4350676
TI  - Detailed hormonal studies during and after pregnancy in a previously
      hypophysectomized patient.

PMID- 4350677
TI  - Corticotrophin-releasing factor activity in hypothalamic extracts of man.

PMID- 4350678
TI  - Iodide perchlorate discharge test in lithium-treated patients.

PMID- 4350679
TI  - Bioassay of calcitonin by determinations of blood calcium-45 levels in rats and
      mice.

PMID- 4350680
TI  - Remitting signs in cerebral mass lesions.

PMID- 4350681
TI  - Studies in children with impetigo. Bacteriology, serology, and incidence of
      glomerulonephritis.

PMID- 4350682
TI  - Guillain-Barre syndrome. Occurrence following combined mumps-rubella vaccine.

PMID- 4350683
TI  - Hereditary recurrent brachial neuropathy.

PMID- 4350684
TI  - [Adenosarcoma of the breast, case report].

PMID- 4350686
TI  - [Release of medical records to physicians for continued treatment].

PMID- 4350687
TI  - Decrease in HCG--binding capacity of target tissues influenced by hypophysectomy.

PMID- 4350688
TI  - Vascular damage and lipid peroxidation in choline-deficient rats.

PMID- 4350685
TI  - [Therapy of primary hyperlipoproteinemia types IIa, IIb and IV using beta
      pyridylcarbinol Study on three phases under ambulatory conditions].

PMID- 4350689
TI  - The phosphorylases system of the cardiac muscle of normal and reserpinized rats
      poisoned with 2,4-dinitrophenol.

PMID- 4350690
TI  - Alterations in lipid metabolism following trauma in rabbits.

PMID- 4350691
TI  - Distribution of a renin-like enzyme in the bovine adrenal gland.

PMID- 4350692
TI  - The reaction of Ca ++ with the inner and outer membrane of mitochondria.

PMID- 4350694
TI  - pH-dependent nuclear magnetic resonance spectra of  15 N-enriched glycine. Line
      shape and relaxation studies.

PMID- 4350693
TI  - [Sodium thioglycolate and hypothalamo-neurohypophysial hormones].

PMID- 4350695
TI  - Crystal and molecular structure of the salt (1-methylnicotinamide)(+) aden-9
      ylacetate(-) dihydrate. A model for the intramolecular interactions of oxidized
      nicotinamide adenine dinucleotide.

PMID- 4350696
TI  - Synthesis of 6'-cyano-6'-deoxyhomoadenosine-6'-phosphonic acid and its phosphoryl
      and pyrophosphoryl anhydrides and studies of their interactions with adenine
      nucleotide utilizing enzymes.

PMID- 4350697
TI  - Antibody affinity chromatography of hog and bovine spleen DNase II.

PMID- 4350698
TI  - Analysis of corticosteroids in mixtures by gradient elution liquid
      chromatography.

PMID- 4350699
TI  - Differential responses of crab neuromuscular synapses to cesium ion.
AB  - Excitatory postsynaptic potentials (EPSP's) generated in crab muscle fibers by a
      single motor axon, differ in amplitude and facilitation. Some EPSP's are large at
      low frequencies of stimulation and show little facilitation; others are smaller
      and show pronounced facilitation. When K(+) is replaced by Cs(+) in the
      physiological solution, all EPSP's increase in amplitude, but small EPSP's
      increase proportionately more than large ones. Quantal content of transmission,
      determined by external recording at single synaptic regions, undergoes a much
      larger increase at facilitating synapses. The increase in quantal content of
      transmission is attributable to prolongation of the nerve terminal action
      potential in Cs(+). After 1-2 h of Cs(+) treatment, defacilitation of synaptic
      potentials occurs at synapses which initially showed facilitation. This indicates
      that Cs(+) treatment drastically increases the fraction of the "immediately
      available" transmitter store released by each nerve impulse, especially at
      terminals with facilitating synapses. It is proposed that facilitating synapses
      normally release less of the "immediately available" store of transmitter than
      poorly facilitating synapses. Possible reasons for this difference in performance
      are discussed.

PMID- 4350700
TI  - The action of streptolysin S on mouse-liver mitochondria.

PMID- 4350701
TI  - Prevalence of cytomagalovirus antibodies in the population of Northern Greece.

PMID- 4350702
TI  - Functional changes in motoneurones of hemiparetic patients.
AB  - Forty-six patients have been studied after upper motor neurone lesions of
      cerebrovascular origin. The numbers of functioning motor units in extensor
      digitorum brevis muscles were reduced to approximately half between the second
      and sixth months after a hemiplegic episode. The surviving motor units tended to
      have slow twitches and appeared to increase their sizes after the lesions had
      been present for about 20 months. The findings are explained on the basis of
      transsynaptic changes in alpha-motoneurones after degeneration of corticospinal
      fibres.

PMID- 4350703
TI  - Neuromuscular block after intra-arterially injected acetylcholine. 1.
      Introduction, methods, and technique.
AB  - The neuromuscular depolarizing block induced by intra-arterially injected ACh was
      studied to determine the variability in the same subject and in different
      subjects without disorders at the motor end-plate. Amplitude of action potentials
      of the opponens pollicis muscle evoked by intermittent repetitive supramaximal
      stimulation of the median nerve at the wrist were recorded for one hour from the
      beginning of ACh injection. The features of prompt and late depression stages
      after the injection were analysed statistically. Re-testing of the same subjects
      after a while shows that, in spite of all efforts to maintain the same
      experimental conditions, variations do occur in late depression. Time course and
      duration are particularly affected, while the degree of depression is altered but
      slightly. The presence of such variations limits this test to evaluation of the
      influence of other factors only within their already established statistical
      limits.

PMID- 4350704
TI  - Neuromuscular block after intra-arterially injected acetylcholine. 2. Effects of
      ACTH treatments as possible detectors of desensitization level in the receptor
      site.
AB  - It has been suggested that the effect of ACTH in myasthenia gravis may be
      ascribed to an action involving neuromuscular transmission which favours
      repolarization processes, with a tendency towards hyperpolarization of the
      membranes of muscle fibres and motor nerve endings. A similar mechanism has been
      postulated for the action of ACTH in epilepsy (Klein, 1970). A direct or indirect
      action on nerve membrane would interfere with depolarization. There is evidence
      of raised concentration of intracellular potassium and increased outflow of
      sodium ions which would cause hyperpolarization of the membrane. This paper
      studies the effect of ACTH on the late block of neuromuscular transmission caused
      by acetylcholine (ACTH).

PMID- 4350705
TI  - Recruitment order of motor units in man: significance of pre-existing state of
      facilitation.
AB  - It has been shown in previous investigations that the recruitment order of motor
      units is different in tonic and in phasic voluntary activity. The significance of
      the pre-existing state of facilitation in the motoneurone pool for the
      recruitment of units is studied, using the phasic flexion reflex in the anterior
      tibial muscle as test reflex. It is shown that the recruitment order of units in
      a series of reflexes (1) is unstable if the subject does not expect the stimulus;
      (2) is stable and identical with that in tonic activity if the subject
      subliminally facilitates the motoneurone pool before the reflex activation; (3)
      is stable and almost identical with that in tonic activity if the subject expects
      the stimulus and therefore involuntarily influences the motoneurone pool; (4) is
      stable and similar to that in phasic voluntary activity if the subject inhibits
      the motoneurone pool before the activation and the stimulus strength thus
      consequentially is increased; and (5) is influenced by blockade of the
      proprioceptive afferent impulses from the muscle. It is concluded that normal man
      can select in advance the recruitment order of motor units most appropriate for
      the work intended.

PMID- 4350706
TI  - Post-ischaemic paraesthesiae in diabetes mellitus.
AB  - A quantitative assessment of post-ischaemic paraesthesiae has been made in 50
      diabetic subjects and in a group of healthy age-matched controls. The results
      show a highly significant diminution of the paraesthetic response in the diabetic
      subjects. The degree of depression of the paraesthetic response was associated
      with the duration of the disease and the severity of the metabolic abnormality as
      determined by the degree of insulin dependence. Diabetics with the juvenile onset
      type of the disease were more adversely affected than those with the maturity
      onset type. There was no consistent relationship between the degree of depression
      of the paraesthesiae and the presence of peripheral neuropathy. The significance
      of these results is discussed in relation to the factors which determine the
      composition of the ionic micro-environment of myelinated nerve and the level of
      electrical excitability of the nerve fibre.

PMID- 4350707
TI  - Molecular weight determination of Sendai RNA by dimethyl sulfoxide gradient
      sedimentation.
AB  - The molecular weight of the large RNA of Sendai virus has been determined by
      sedimentation analysis in sucrose gradients containing 99% dimethyl sulfoxide
      (DMSO) to be 2.3 x 10(6). Sendai RNA recovered from 99% DMSO was found to
      cosediment with nondenatured Sendai RNA at 46 to 48s in ordinary sucrose
      gradients. The molecular weight value of 2.3 x 10(6) is considerably smaller than
      the estimates of 6 x 10(6) to 7 x 10(6) determined under nondenaturing
      conditions, suggesting a unique structure for Sendai RNA.

PMID- 4350708
TI  - Growth of coliphage T7 in Salmonella typhimurium.
AB  - A mutant of Salmonella typhimurium was found to be sensitive to killing by
      coliphage T7 because of an alteration in its surface properties. However, the
      infections were abortive and studies with (32)P-labeled T7 grown in Escherichia
      coli B (T7.B) indicated that the phage DNA was restricted by S. typhimurium. When
      a mutant T7 which survived the restriction and produced plaques on Salmonella
      (T7.S) was passed through one cycle of growth in E. coli B, its ability to grow
      in Salmonella was lost, indicating that host-controlled restriction and
      modification are operative in this system. Restrictionless S. typhimurium mutants
      were isolated that permit the growth of not only T7.S but also T7.B and coliphage
      T3. The physiology of T7 production in the restrictionless host is nearly
      identical to that in Escherichia coli.

PMID- 4350709
TI  - Infectivity and RNA patterns as functions of high- and low-dilution passage of
      murine sarcoma-leukemia virus: evidence for autointerference within an
      oncornavirus population.
AB  - Heterogeneity of buoyant density and RNA content of virions of Moloney murine
      leukemia-sarcoma complex [MSV (MLV)] was the result of passage at low dilution.
      Heterogeneous stocks revealed two major RNA components in the population, with
      the smaller component, apparent mol wt 4 x 10(6) to 5 x 10(6), becoming
      predominant upon serial passage at low dilution. Concomitantly, infectivity
      titers of both MLV and MSV decreased upon serial passage at low dilution. MSV
      (MLV) passaged at high dilution retained high titers and a rather homogeneous
      high-molecular-weight RNA population characteristic of high-buoyant-density
      virions. Interference of both MLV and MSV replication was demonstrated by
      employing mixed inocula containing both low- and high-dilution passage stocks of
      MSV (MLV). In contrast to results with MSV (MLV), MLV freed of MSV by limit
      dilution did not show heterogeneity of buoyant density or of RNA when propagated
      at low dilution.

PMID- 4350710
TI  - Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. V. Isolation
      of additional hybrids which differ in their simian virus 40-specific biological
      properties.
AB  - Four new nondefective adenovirus 2 (Ad2)-simian virus 40 (SV40) hybrid viruses
      have been isolated. Although these viruses (designated Ad2(+)ND(2), Ad2(+)ND(3),
      Ad2(+)ND(4), and Ad2(+)ND(5)) were clonal derivatives of the same Ad2-SV40 hybrid
      population, they differ significantly from each other and from the previously
      isolated nondefective hybrid, Ad2(+)ND(1), in their biological properties or in
      the amount of SV40-specific RNA induced during lytic infection.Like Ad2(+)ND(1),
      Ad2(+)ND(2), and Ad2(+)ND(4) pass serially in both human embryonic kidney (HEK)
      and primary African green monkey kidney cells. In contrast, Ad2(+)ND(3) and
      Ad2(+)ND(5) pass serially only in HEK cells. Ad2(+)ND(2) is like Ad2(+)ND(1) in
      that it induces the SV40 U antigen, but not SV40 T antigen; however, in contrast
      to the perinuclear SV40 antigen induced by Ad2(+)ND(1), the SV40 antigen induced
      by Ad2(+)ND(2) is located peripherally in the cytoplasm as well as in the
      perinuclear region of infected cells. Ad2(+)ND(4) induces both the SV40 T and U
      antigens. Ad2(+)ND(3) and Ad2(+)ND(5) do not induce serologically detectable SV40
      antigens and are distinguished from each other on the basis of the relative
      quantities of SV40-specific RNA which they induce. The induction of different
      SV40-specific functions suggests the incorporation of different segments of SV40
      DNA within the genomes of the respective hybrid viruses.

PMID- 4350711
TI  - Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. VI.
      Characterization of the DNA from five nondefective hybrid viruses.
AB  - Certain biophysical characteristics of the DNA from each of the five nondefective
      adenovirus 2 (Ad2)-simian virus 40 (SV40) hybrid viruses (Ad2(+)ND(1),
      Ad2(+)ND(2), Ad2(+)ND(3), Ad2(+)ND(4), Ad2(+)ND(5)) have been determined. The
      guanine plus cytosine content varied from 55 to 57% and was not significantly
      different from that of nonhybrid Ad2 (56%), and the hybrid DNA molecules had mean
      molecular lengths which were similar to that of the standard, Ad2. The Ad2 and
      SV40 components of each hybrid were linked by alkali-resistant, presumably
      covalent bonds. The percentage of SV40 DNA in each hybrid virus was determined by
      hybridization with SV40 complementary RNA in a calibrated system. The results
      indicate that each hybrid virus DNA contains a different percentage of SV40
      nucleotide sequences. The estimated size of the SV40 DNA component varies from
      48,000 daltons for Ad2(+)ND(3) to 840,000 daltons for Ad2(+)ND(4), the latter
      being equivalent to between one-fourth and one-third of the SV40 genome.

PMID- 4350712
TI  - Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. VII.
      Characterization of the simian virus 40 RNA species induced by five nondefective
      hybrid viruses.
AB  - Five nondefective adenovirus 2 (Ad2)-simian virus 40 (SV40) hybrid viruses have
      been isolated and found to contain segments of SV40 DNA covalently linked to Ad2
      DNA. The quantity of SV40 DNA present is a stable characteristic of each hybrid
      virus, and varies from less than 5% (in Ad2(+)ND(3)) to more than 30% (in
      Ad2(+)ND(4)) of the SV40 genome. We have characterized the SV40 portions of these
      hybrids by relating the SV40-specific RNA sequences transcribed in cells infected
      with each hybrid virus to those transcribed in cells infected with each of the
      other hybrid viruses and with SV40 itself. RNA-DNA hybridization-competition
      experiments indicate that the number of unique SV40 RNA sequences transcribed in
      infected cells is proportional to the size of the SV40 DNA segment contained
      within each hybrid and, in the case of the three hybrids which induce detectable
      SV40-specific antigens, to the number of SV40 antigens induced. Furthermore, the
      SV40-specific RNA sequences transcribed from any one of the hybrids are
      completely represented in the RNA transcribed from all other hybrids with longer
      SV40 segments. Thus, the SV40 DNA regions in the five hybrid viruses appear to
      contain some nucleotide sequences in common. The SV40-specific RNA transcribed
      from Ad2(+)ND(4), the hybrid containing the largest SV40 segment, is
      qualitatively similar to the SV40-specific RNA transcribed early (i.e., prior to
      viral DNA replication) in SV40 lytic infection. Thus, it appears that no
      significant amount of late SV40 DNA is transcribed during infection by any of the
      five nondefective Ad2-SV40 hybrid viruses.

PMID- 4350713
TI  - Preferred site for initiation of RNA transcription by Escherichia coli RNA
      polymerase within the simian virus 40 DNA segment of the nondefective adenovirus
      simian virus 40 hybrid viruses Ad2 + ND 1  and Ad2 + ND 3 .
AB  - The DNA of simian virus 40 (SV40) was transcribed into RNA by Escherichia coli
      RNA polymerase at 18 to 24 C after synchronization of the initiation of RNA
      synthesis. After a brief synthetic period the RNA product contained relatively
      large amounts of sequences derived from a limited segment of SV40 DNA. The source
      for this pulse-labeled RNA was found to be a portion of the segment of SV40 DNA
      included within the nondefective adenovirus (Ad)-SV40 hybrid viruses, Ad2(+)ND(1)
      and Ad2(+)ND(3). After synthesis with [gamma-(32)P] ATP, Ad2(+)ND(1) and
      Ad2(+)ND(3) DNA transcripts contained an initial sequence missing from Ad2
      transcripts. This sequence was identified as an initiation sequence for
      polymerase transcription of the SV40 DNA. Thus, there is a preferred site for
      initiation of in vitro transcription on the segment of SV40 DNA common to the
      nondefective Ad2(+)ND(1) and Ad2(+)ND(3) hybrid viruses.

PMID- 4350714
TI  - Temperature-sensitive simian virus 40-transformed cells: phenomena accompanying
      transition from the transformed to the "normal" state.
AB  - Temperature-sensitive simian virus (SV 40)-transformed 3T3 cells (tsSV3T3), which
      express the transformed phenotype when growing at 32 C but not at 39 C, were used
      to study changes in growth behavior during shift-up or shift-down experiments. In
      cultures of tsSV3T3 cells which had reached or were beyond monolayer density at
      32 C, DNA synthesis reached very low levels within 24 to 48 h after shift-up.
      When cells which had been allowed to grow to high densities at 32 C were shifted
      to 39 C, not only cell growth stopped, but within two to three days the cultures
      shed a large number of cells into the medium. These cells were nonviable, and
      shedding stopped only when the number of cells attached had been reduced to that
      characteristic of the saturation density at 39 C. The remaining attached cells
      were viable and after the shift to 32 C were again able to grow from the
      monolayer to high cell densities. This behavior has been compared with that of
      normal 3T3 and wild-type SV3T3 cells under different conditions. We have also
      isolated new tsSV3T3 lines, using cells which had been infected with non
      mutagenized wild-type SV40. This further demonstrates that the temperature
      sensitivity of these lines is due to a cellular rather than a viral mutation.

PMID- 4350715
TI  - Structural rearrangement and subunit composition of RNA from released Soehner
      Dmochowski murine sarcoma virions.
AB  - Two types of genomic, high-molecular-weight RNA species were found in Soehner
      Dmochowski murine sarcoma virions released from virus-induced rat tumor cells
      grown in tissue culture. The type of RNA species observed depended on the length
      of exposure of the tumor cells to radioactive precursor. Early RNA of virions
      labeled up to 4 h with radioactive uridine had a sedimentation coefficient of
      50S, and late RNA of virions labeled for 24 h had a sedimentation coefficient of
      58S. Thermal transitions of early and late RNA indicated a difference in the
      configuration or structure of these two types of RNA. The late RNA may represent
      either a different configurational state of the early RNA or an aggregate
      molecule of two early RNA components joined together. Heat dissociation revealed
      that the major subunit of both RNA types was a 28S species, which was not
      susceptible to degradation by the addition of micrococcal nuclease to virions. A
      transitional, intermediate RNA species with a sedimentation coefficient of 37 to
      40S was detected when early RNA was dissociated by dimethyl sulfoxide or heat at
      temperatures suboptimal for complete conversion. No free RNA subunit components
      were detected in virions harvested at intervals as short as 30 s or 5 min. A
      model for the assembly of genomic RNA from 28S RNA subunits is proposed.

PMID- 4350716
TI  - Inhibition in the joining of DNA intermediates to growing simian virus 40 chains.
AB  - Viral DNA synthesis was inhibited for 1 h by the addition of 5-fluorodeoxyuridine
      (FUdR) to simian virus 40 (SV40)-infected cultures at 28 to 30 h postinfection.
      The subsequent addition of (3)H-thymidine to the inhibited cultures reverses the
      effect of the inhibitor, and during a 1-min labeling period there is rapid
      synthesis of SV40 DNA. By alkaline sedimentation analysis, it is observed that in
      FUdR-treated cultures there is synthesis of 4S SV40 DNA intermediates but there
      is a block in the joining of these intermediates to growing SV40 chain cultures.
      In addition to 4S fragments that are associated with replicating SV40 molecules,
      there is accumulation of SV40 DNA in the 6 to 8S region which is observed in
      neutral sucrose gradients. In an inhibited culture that is pulsed for 1 min with
      (3)H-thymidine and then chased for 10 min, accumulation of a Component II (Comp.
      II)-like material is observed. This Comp. II has the same neutral sedimentation
      characteristics and yields the same R(I) restriction endonuclease product as does
      authentic Comp. II. However, in alkali it is seen that it is composed of
      fragmented SV40 DNA. The basis for the failure of 4S fragments to join to growing
      SV40 chains is discussed. A model in which there is a requirement for two DNA
      polymerases and a ligase to permit SV40 DNA chain growth is proposed which is
      consistent with the data presented.

PMID- 4350717
TI  - Avian oncornavirus group-specific antigen: detection and quantification by
      radioimmunoassay.
AB  - A double-antibody competitive-inhibition radioimmunoassay for avian group
      specific antigen is described. A viral protein preparation, consisting primarily
      of gs-1, was labeled with radioiodine. Hamster and rabbit antisera were reacted
      with the labeled antigen, and the resultant antibody-antigen complexes were
      precipitated with the appropriate antiglobulin. Standard curves based on the
      inhibition of binding of labeled antigen to antibody after preincubation with
      unlabeled antigen were prepared. These showed the lower limit of sensitivity to
      be 2 to 10 ng of unlabeled protein when labeled antigen of 2,000 to 5,000 counts
      per min per ng of specific activity was used in the assay. Extracts of avian
      oncornavirus-infected cells, likewise, were able to inhibit binding of labeled
      antigen. This technique will be very useful for the quantification of small
      amounts of oncornavirus group-specific protein.

PMID- 4350718
TI  - Relationship of reticuloendotheliosis virus to the avian tumor viruses: nucleic
      acid and polypeptide composition.
AB  - The RNA content and polypeptide composition of reticuloendotheliosis virus (REV)
      was compared to that of C-type RNA tumor viruses. Two RNA species with
      approximate sedimentation values of 64S and 4S were observed after sucrose
      gradient centrifugation of RNA extracted from purified REV. The high-molecular
      weight RNA species of REV sedimented slightly faster than that of the Bryan
      strain of Rous sarcoma virus (RSV). Although these characteristics were
      consistent with those of other C-type RNA tumor viruses, significant differences
      were observed when the polypeptide composition of REV was compared with that of
      RSV possessing envelope determinants of Rous-associated virus RAV-2 and RAV-3.
      Five polypeptides of which two were glycosylated were resolved by polyacrylamide
      gel electrophoresis. The major nonglycosylated polypeptide of REV did not
      comigrate with that of RSV (RAV-2)-RSV(RAV-3). The majority of the group-specific
      antigen reactivity resides in this major nonglycosylated polypeptide of avian
      tumor viruses and comigrates when proteins of several avian tumor viruses are
      subjected to coelectrophoresis. This difference in the migration of the major
      polypeptide of REV and RSV(RAV-2)-RSV(RAV-3) may explain the absence of avian
      tumor virus group-specific antigen in REV.

PMID- 4350719
TI  - Quantitative determination and location of newly synthesized virus-specific
      ribonucleic acid in chicken cells infected with Rous sarcoma virus.
AB  - A sensitive and quantitative nucleic acid hybridization assay for the detection
      of radioactively labeled avian tumor virus-specific RNA in infected chicken cells
      has been developed. In our experiments we made use of the fact that DNA
      synthesized by virions of avian myeloblastosis virus in the presence of
      actinomycin D (AMV DNA) is complementary to at least 35% of the sequences of 70S
      RNA from the Schmidt-Ruppin strain (SRV) of Rous sarcoma virus. Annealing of
      radioactive RNA (either SRV RNA or RNA extensively purified from SRV-infected
      chicken cells) with AMV DNA followed by ribonuclease digestion and Sephadex
      chromatography yielded products which were characterized as avian tumor virus
      specific RNA-DNA hybrids by hybridization competition with unlabeled 70S AMV RNA,
      equilibrium density-gradient centrifugation in Cs(2)SO(4) gradients, and by
      analysis of their ribonucleotide composition. The amount of viral RNA synthesized
      during pulse labeling with (3)H-uridine could be quantitated by the addition of
      an internal standard consisting of (32)P-labeled SRV RNA prior to purification
      and hybridization. This quantitative assay was used to determine that, in SRV
      infected chicken cells labeled for increasing lengths of time with (3)H-uridine,
      labeled viral RNA appeared first in a nuclear fraction, then in a cytoplasmic
      fraction, and still later in mature virions. This observation is consistent with
      the hypothesis that RNA tumor virus RNA is synthesized in the nucleus of infected
      cells.

PMID- 4350720
TI  - [The effect of L-aspartic acid in isoproterenol necrosis of cardiac muscle].

PMID- 4350721
TI  - [Histamine-sensitizing action of Bordetella pertussis strains isolated from
      patients].

PMID- 4350722
TI  - [Dissemination of enteroviruses in the human environment. I. Presence of
      poliovirus in various parts of vegetable plants grown on infected soil].

PMID- 4350723
TI  - Stimulation of the collagen biosynthetic pathway by factors isolated from
      experimentally-injured liver.

PMID- 4350724
TI  - Action of intracerebroventricular dibutyryl cyclic AMP on amobarbital anaesthesia
      in rats.

PMID- 4350725
TI  - Amniotic fluid phospholipids in early gestation.

PMID- 4350726
TI  - Pulmonary surfactant. Is the fetal adrenal necessary?

PMID- 4350727
TI  - Tectal activity and eye movements during paradoxical sleep in cats.

PMID- 4350728
TI  - The effects of conditioned behaviour and environmental factors on plasma
      corticosteroid levels in pigs.

PMID- 4350729
TI  - Electrographic correlates of sleep behavior in a primitive mammal, the armadillo
      Dasypus novemcinctus.

PMID- 4350730
TI  - Rewarding and aversive brain stimulation opposite effects on medial thalamic
      units.

PMID- 4350731
TI  - The role of the dorsal nerves of the penis in the sexual behaviour of the male
      rhesus monkey.

PMID- 4350732
TI  - Path neuron system of medial forebrain bundle as a possible substrate for
      hypothalamic self-stimulation.

PMID- 4350733
TI  - Drinking to intracerebral angiotensin II and carbachol: dose-response
      relationships and ionic involvement.

PMID- 4350734
TI  - Cellular responses to cyclic AMP.

PMID- 4350735
TI  - Enzymatic properties of a repressible acid phosphatase in Neurospora crassa.

PMID- 4350737
TI  - [Recurrent digital fibromas in childhood].

PMID- 4350736
TI  - [Titrations of Herpes simplex virus in cell cultures derived from normal uterine
      cervix and from cervical cancer].

PMID- 4350738
TI  - [Fourteen-year-old contrast media deposits in both Fallopian tubes following
      hysterosalpingography].

PMID- 4350739
TI  - Neoplasms of the sella turcica region in Ibadan, Nigeria.

PMID- 4350740
TI  - [Intracranial expansive processes in children in Senegal].

PMID- 4350741
TI  - [Nervous system tumors in Ivory Coast].

PMID- 4350742
TI  - Homogenous immunochemical drug assays.

PMID- 4350743
TI  - Immunological assays for drugs in biological samples.

PMID- 4350744
TI  - Comparative evaluation of methods for laboratory diagnosis of herpetic eye
      disease.

PMID- 4350746
TI  - [Glomus jugulare tumor].

PMID- 4350748
TI  - Subcellular distribution of adenyl cyclase and phosphodiesterase in Acanthamoeba
      palestinensis.

PMID- 4350745
TI  - Incisional and peritoneal infection after emergency celiotomy.

PMID- 4350747
TI  - Quillaiate of choline iodide: a new monoquaternary neuromuscular blocking agent.

PMID- 4350749
TI  - Studies with phosphodiesterase. 3. Two forms of the enzyme from human blood
      platelets.

PMID- 4350750
TI  - Substrate specificity of hog plasma angiotensin-converting enzyme.

PMID- 4350752
TI  - [Aldolase isoenzymes in regenerating liver].

PMID- 4350753
TI  - [Changes in karyotype of oncogenic BHK 21 clone 13 strain when put upon
      adaptation to culture in suspension].

PMID- 4350751
TI  - [Therapeutic effect of the (+)-catechin on biochemical disorders of the liver in
      the ethanol intoxicated rat].

PMID- 4350754
TI  - [Fractionation of phospholipid extracted from tubercle bacillis and serological
      specificity of its components].

PMID- 4350755
TI  - [Purine phosphoribosylphosphate transferase in erythrocytes of chickens].

PMID- 4350757
TI  - Histamine sensitizing activity of lentinan, an antitumour polysaccharide.

PMID- 4350758
TI  - A quantitative investigation of the response to injury of the central nervous
      system of rats treated with ACTH and triiodothyronine.

PMID- 4350756
TI  - The renin-angiotensin system in urinephrectomized adrenalectomized rats.

PMID- 4350759
TI  - The primary tissue culture of rat adult decapsulated adrenal glands:
      radioautographic studies on the metabolic effects of   1-24 -ACTH.

PMID- 4350760
TI  - Radioimmunoassay of angiotensin II in rat plasma.

PMID- 4350762
TI  - [Islet cell tumor of the pancreas].

PMID- 4350761
TI  - [Benign hepatic tumors].

PMID- 4350764
TI  - Further studies on the chromatographic behaviour of dinucleoside monophosphates.

PMID- 4350763
TI  - Strength modification of polycarboxylate cement with fillers.

PMID- 4350766
TI  - Application of direct spectrophotometry to the analysis of chromatograms. 3. A
      new micro thin-layer chromatoplate and its application to the analysis of
      tocopherols.

PMID- 4350765
TI  - Preparative argentation column chromatography for separation of sterols from
      orange vesicles.

PMID- 4350767
TI  - Detection of naturally fluorescent pesticides on silica gel layers.

PMID- 4350768
TI  - [Separation of nucleosides-3'-monophosphates by ion exchange chromatography].

PMID- 4350769
TI  - The formation of synapses in reinnervated and cross-reinnervated adult avian
      muscle.
AB  - 1. A study has been made of the formation of synapses in spontaneously
      reinnervated and cross-reinnervated anterior latissimus dorsi (ALD) and posterior
      latissimus dorsi (PLD) muscles of adult fowls.2. Denervated ALD and PLD muscle
      fibres have a uniform and high sensitivity to iontophoretically applied
      acetylcholine (ACh). During early reinnervation the sensitivity distribution to
      ACh of the ALD muscle fibres begins to return to normal before synaptic
      potentials can be evoked. The normal ACh sensitivity distribution of PLD muscle
      fibres is also restored after reinnervation. After cross-reinnervation of the ALD
      and PLD muscles the ACh sensitivity distribution of many of the muscle fibres is
      again restored to normal.3. Reinnervating and cross-reinnervating ALD nerve
      terminals showed a greater than normal degree of facilitation of transmitter
      release when a test impulse was applied at various intervals after a conditioning
      impulse. Cross-reinnervating PLD nerve terminals showed facilitation of
      transmitter release rather than the normal depression in a conditioning-test
      impulse sequence.4. The distribution of nerve terminals over the surface of
      spontaneously reinnervated and cross-reinnervated ALD and PLD muscle fibres has
      been determined from an examination of the sensitivity distribution to applied
      ACh, the graded versus all-or-none nature of the evoked potential and the
      distribution of cholinesterase stained synapses.5. The results suggest that the
      innervation pattern of individual ALD and PLD muscle fibres is restored both
      after spontaneous reinnervation and cross-reinnervation.

PMID- 4350770
TI  - The orderly recruitment of human motor units during voluntary isometric
      contractions.
AB  - 1. The contractile properties of human motor units from the first dorsal
      interosseus muscle of the hand were studied during voluntary isometric
      contractions using recently developed techniques.2. The twitch tensions produced
      by motor units varied widely from about 0.1-10 g. The twitch tension of a motor
      unit varied nearly linearly as a function of the level of voluntary force at
      which it was recruited over the entire range of forces studied (0-2 kg).3. The
      number of additional motor units recruited during a given increment in force
      declined sharply at high levels of voluntary force. This suggests that even
      though the high threshold units generate more tension, the contribution of
      recruitment to increases in voluntary force declines at higher force levels.4.
      Contraction times for these motor units varied from 30 to 100 msec. Over 80% had
      contraction times less than 70 msec, and might be classed as fast twitch motor
      units. The larger motor units, which were recruited at higher threshold forces,
      tended to have shorter contraction times than the smaller units.

PMID- 4350771
TI  - Effects of muscle stretch on transmitter release at end-plates of rat diaphragm
      and frog sartorius muscle.
AB  - 1. Miniature end-plate potentials (m.e.p.p.s) and end-plate potentials were
      recorded intracellularly at neuromuscular junctions of the frog sartorius muscle
      and the rat diaphragm before, during and after muscle stretch.2. Stretch
      increased the frequency of the m.e.p.p.s and the mean quantum content (m) at end
      plates of the sartorius muscle.3. Stretch enhanced m.e.p.p. frequency of the
      sartorius muscle in normal Ringer solution as well as in solutions high in
      magnesium and low in calcium content. In addition, an increase in frequency
      occurred in the presence of tetrodotoxin and in the absence of neostigmine
      methylsulphate.4. The magnitude of the increase in m.e.p.p. frequency in the
      sartorius muscle was negatively correlated with the control frequency.5. In
      contrast to the above findings at sartorius end-plates, muscle stretch did not
      affect the frequency of m.e.p.p.s or the m values at end-plates of the rat
      diaphragm.

PMID- 4350772
TI  - [Use of a synthetic corticostimuline in patients with severe respiratory
      insufficiency treated by assisted ventilation].

PMID- 4350773
TI  - Maternal infections and the developing foetus.

PMID- 4350774
TI  - [Body height increase and secretion of somatotropin in children with variously
      treated hephrotic syndromes].

PMID- 4350775
TI  - Maternal cytomegalovirus excretion and perinatal infection.

PMID- 4350776
TI  - Patterning mechanisms, patterned reflexes, and attack behavior in cats.

PMID- 4350777
TI  - Influence of levodopa on serum levels of anterior pituitary hormones in man.

PMID- 4350778
TI  - Neural pathways mediating adrenocortical responses to photic and acoustic
      stimuli.

PMID- 4350779
TI  - Management of nursing care on a psychiatric service.

PMID- 4350780
TI  - Patterns of development of adenyl cyclase activity and norepinephrine
      responsiveness in the rat.

PMID- 4350781
TI  - Sleep patterns in hyperphenylalaninemia: a lesson on serotonin to be learned from
      phenylketonuria.

PMID- 4350782
TI  - Characterization of guinea pig C-type virus.

PMID- 4350783
TI  - Inhibition of glucose oxidation and fatty acid synthesis in liver slices from
      fed, fasted and fasted-refed rats by glucagon, epinephrine and cyclic adenosine
      3',5'-monophosphate.

PMID- 4350784
TI  - Effect of the synthetic peptide, Sq 20,881, on distribution of blood flow in the
      rat.

PMID- 4350785
TI  - Estrogen-topographical localization of estrogen-concentrating cells in the rat
      spinal cord following  3 H-estradiol administration.

PMID- 4350786
TI  - HL-A antigens of human tumor-derived cell lines and viral transformed fibroblasts
      in culture.

PMID- 4350787
TI  - Adrenal and plasma corticosterone and pituitary and plasma ACTH in alloxan
      diabetic rats.

PMID- 4350788
TI  - Immunosuppression and increased susceptibility to Japaneses B encephalitis virus
      in Trichinella spiralis-infected mice.

PMID- 4350789
TI  - Effects of prostaglandins PGE 2  and PGF 2   on the adenyl cyclase activity of
      various segments of the immature rabbit oviduct and uterus.

PMID- 4350790
TI  - Endogenous triglyceride and glycogen in perfused rat hearts.

PMID- 4350791
TI  - B-scan ultrasound in the evaluation of pediatric abdominal masses.

PMID- 4350792
TI  - The incidence of osseous involvement in lung cancer, with special reference to
      the development of osteoblastic changes.

PMID- 4350793
TI  - Mammary duct injection.

PMID- 4350794
TI  - [Distribution of the smallpox vaccine virus in the body of irradiated and
      nonirradiated rabbits].

PMID- 4350795
TI  - [Clinical and neurological aspects of 2 cases of leucine-sensitive idiopathic
      hypoglycemia in the evolutional age].

PMID- 4350796
TI  - Evidence on the constitutive nature of a p-nitrophenylphosphatase of
      Streptococcus mutans.

PMID- 4350797
TI  - Significance of a p-nitrophenylphosphatase for Streptococcus mutans.

PMID- 4350798
TI  - Epidemiologic characteristics of presumed ocular histoplasmosis.

PMID- 4350799
TI  - Changes in lipid values and lipoprotein patterns of serum samples contaminated
      with bacteria.

PMID- 4350800
TI  - Automated stopped-flow kinetic analysis of serum enzymes.

PMID- 4350801
TI  - pH dependence of the renin reaction: a modification of commercial renin activity
      radioimmunoassay kits.

PMID- 4350802
TI  - Antiviral activity of isoprinosine in vitro and in vivo.

PMID- 4350803
TI  - Corneal degeneration.

PMID- 4350804
TI  - Effect of the pH of the incubation medium on glycolysis and respiration in
      Saccharomyces cerevisiae.

PMID- 4350805
TI  - Microsomal electron transport: tetrazolium reduction by rat liver microsomal
      NADPH-cytochrome c reductase.

PMID- 4350806
TI  - Bovine hepatic fructose 1,6-diphosphatase: modification of the catalytic and
      allosteric properties by sulfhydryl reagents.

PMID- 4350807
TI  - Protein synthesis directed by encephalomyocarditis virus mRNA. 3. Discrete
      polypeptides translated from a monocistronic messenger in vitro.

PMID- 4350808
TI  - Interaction of viral RNA with Escherichia coli. 3. Synthesis of poliovirus
      specific RNA directed by isolated poliovirus RNA.

PMID- 4350809
TI  - Purification and properties of cyclic phosphodiesterase: 3'-nucleotidase, a
      periplasmic enzyme of Haemophilus influenzae.

PMID- 4350810
TI  - On the source of GABA-containing terminals in the substantia nigra. Electron
      microscopic autoradiographic and biochemical studies.

PMID- 4350811
TI  - Neuronal activity in the association cortex of the cat during sleep, wakefulness
      and anesthesia.

PMID- 4350812
TI  - Compensatory changes in REM sleep time of cats during ad libitum sleep and
      following brief REM sleep deprivation.

PMID- 4350813
TI  - Miniature end-plate potentials: evidence that the intervals are not fit by a
      Poisson distribution.

PMID- 4350814
TI  - Some effects of vinblastine and colchicine on neuromuscular transmission.

PMID- 4350816
TI  - Scorpion venom-induced discharge of catecholamines accompanied by hypertension.

PMID- 4350815
TI  - Action of a GABA-derivative on postsynaptic potentials and membrane properties of
      cats' spinal motoneurones.

PMID- 4350817
TI  - [Comparative study of enzymes produced by 2 kinds of mycelium composing the
      thallus of Corticium rolfsii (Sacc.) Curzi].

PMID- 4350819
TI  - [Cyclic AMP, mediator of glucagon secretion due to amino acids].

PMID- 4350818
TI  - [Increase in the activity of 5 alpha-steroid reductase and 3 alpha-hydroxysteroid
      deshydrogenase in anterior pituitary cytoplasm in the castrated rat].

PMID- 4350820
TI  - [High molecular weight rapidly labelled ribonucleic acid (RNA) and virus
      production in chick fibroblasts infected with avian myeloblastosis virus].

PMID- 4350822
TI  - [Demonstration and histologic localization, by means of an electronic catheter,
      of a natural accumulation of aluminum and silicium in the liver of Rana
      temporaria (vertebrates, amphibians)].

PMID- 4350821
TI  - [Isolation and ultrastructural study of a Papova type virus not neutralized by
      the anti SV 40 reference serum during progressive multifocal
      leukoencephalopathy].

PMID- 4350823
TI  - Ribosome-covered vesicles associated with synthesis and secretion of invertase in
      yeast.

PMID- 4350824
TI  - The long-acting thyroid stimulator.

PMID- 4350826
TI  - Effects of ovarian hormones at the subcellular level.

PMID- 4350825
TI  - Endocrinological implications of prostaglandins.

PMID- 4350827
TI  - Steroid hormones and the differentiation of the central nervous system.

PMID- 4350828
TI  - Polygraphic profile of oral tardive dyskinesia and of rabbit syndrome: for
      quantitative and qualitative evaluation.

PMID- 4350829
TI  - [Psychopharmacology of sleep].

PMID- 4350830
TI  - Gout and pseudogout.

PMID- 4350831
TI  - [Circular resection of the trachea].

PMID- 4350832
TI  - Ultrastructural and lipid biochemical comparisons of human eruptive, tuberous and
      planar xanthomas.

PMID- 4350833
TI  - Virus-induced changes in the endogenous pathway of thymidine in animal cells.

PMID- 4350834
TI  - An ultrastructural analysis of the photoreceptors of the squid and their synaptic
      connections. II. Intraretinal synapses and plexus.

PMID- 4350835
TI  - Identification of a major basic protein in guinea pig eosinophil granules.
AB  - Elucidation of the functions of the eosinophil might be accomplished by analysis
      of the granule constituents. We have purified eosinophils (93% or greater) from
      the peritoneal cavity of the guinea pig and have investigated a variety of
      methods to disrupt cells and liberate intact granules. Lysis in 0.34 M sucrose
      gave the best yield of granules and these had the characteristic morphology of
      eosinophil granules when examined by electron microscopy. Granules were
      solubilized by a variety of treatments and the solutions analyzed by
      polyacrylamide electrophoresis at pH 3 in 6 M urea. Comparison of the
      electrophoretic patterns of solubilized eosinophil and neutrophil granules
      revealed a difference: a major portion (53+/-3%; x +/-1 SE) of the protein from
      the eosinophil granule migrated as a single component. This major band protein
      has a molecular weight between 6,000 and 12,000 daltons and a pI of 10 or
      greater. Analysis of eosinophil granule constituents on Sephadex G-50 revealed
      two main peaks; peak 1 possessed peroxidase activity and peak 2 contained the
      major band protein. These studies indicate that eosinophil granules contain a
      cationic protein of low molecular weight which lacks peroxidase activity and
      which accounts for greater than 50% of granule protein.

PMID- 4350836
TI  - Indirect haemagglutination reaction with varicella-zoster virus antigen.

PMID- 4350837
TI  - An analysis of cylindroma of the head and neck.

PMID- 4350838
TI  - Plasma renin activity during levodopa therapy. Significance of long- and short
      term treatment.

PMID- 4350839
TI  - Stand up and be diagnosed.

PMID- 4350840
TI  - [Neural information for quality of tastes].

PMID- 4350841
TI  - [Pattern formation of movements].

PMID- 4350842
TI  - [A model of the conditioned reflex and its responses].

PMID- 4350843
TI  - [Information processing in the auditory system].

PMID- 4350844
TI  - Reversible inactivation of liver microsomal pyrophosphatase.

PMID- 4350845
TI  - Effect of clofibrate on arginine-induced insulin and glucagon secretion.

PMID- 4350847
TI  - Precursors of plasma triglyceride fatty acids in obesity.

PMID- 4350846
TI  - Effects of a purified growth hormone releasing factor on growth hormone secretion
      and pituitary cyclic nucleotide content.

PMID- 4350848
TI  - Increase of microsomal glucose-6-phosphatase activity after chronic ethanol
      administration.

PMID- 4350849
TI  - Triglyceride removal efficiency and lipoprotein lipases: effects of Oxandrolone.

PMID- 4350850
TI  - Brain, speech and consciousness.

PMID- 4350851
TI  - Sensory transduction. II. Visual receptors. Quantum efficiency of isomerization.

PMID- 4350852
TI  - [Primary herpetic stomatitis in young children].

PMID- 4350853
TI  - [Pathogenesis of the ECG changes in respiratory viral infections in children].

PMID- 4350854
TI  - [Dispensary observation and treatment of children and adolescents with physical
      and sexual retardation].

PMID- 4350856
TI  - Immunization of chickens for the control of infectious bursal disease.

PMID- 4350855
TI  - [Activity of some blood serum enzymes in the treatment of alcoholic hallucinosis,
      alcoholic paranoia and depression syndrome in chronic alcoholism].

PMID- 4350857
TI  - The inheritance of resistance to subgroup C leukosis-sarcoma viruses in New
      Hampshire chickens.

PMID- 4350860
TI  - Conversion of glutamic acid to proline in the chick.

PMID- 4350859
TI  - Modification of high temperature and ACTH induced immunodepression by metyrapone.

PMID- 4350858
TI  - Horizontal transmission of turkey herpesvirus to chickens. 2. Some factors
      affecting transmission.

PMID- 4350861
TI  - Regression of Rous sarcomas in two lines of chickens.

PMID- 4350862
TI  - [Catecholamines and the development of the hypophyseal-adrenocortical system in
      the newborn].

PMID- 4350863
TI  - [Interrelationship of the thyroid gland and adrenal cortex postoperatively].

PMID- 4350864
TI  - [Electroencephalograms of insulinoma patients before and in the late periods
      after operation].

PMID- 4350865
TI  - [Participation of vasopressin in the development of compensatory adrenal
      hypertrophy].

PMID- 4350867
TI  - Characteristics of physicians interested in psychiatric education.

PMID- 4350866
TI  - [Effect of some hormones on the "drumstick" nuclei of the neutrophils of female
      and male guinea pigs].

PMID- 4350869
TI  - [Primary epithelioma of the liver revealed by a vertebral metastasis and invasion
      of the adjacent soft tissues].

PMID- 4350868
TI  - [Unusual histological appearance of a tumor of the palm of the hand (mixed tumor
      of the sweat glands?)].

PMID- 4350871
TI  - [Protein structure and optical activity].

PMID- 4350870
TI  - [Kinetic characteristics of biological catalysis and the dynamic structure of
      enzymes].

PMID- 4350872
TI  - [Tumor induction in grey (Armenian) hamsters by the SV40 virus].

PMID- 4350873
TI  - Ovarian tumors in pregnancy. A private hospital ten year survey.

PMID- 4350874
TI  - Carbohydrate metabolism during differentiation (sclerotization) of the myxomycete
      Physarum flavicomum.

PMID- 4350875
TI  - Cortico-fugal facilitation of thalamic transmission.

PMID- 4350876
TI  - Discussion: functional studies of thalamic internuclear interactions.

PMID- 4350877
TI  - The second international standard for polymyxin B.
AB  - Since supplies of the first International Standard for Polymyxin B were
      exhausted, it was replaced by a second international standard the potency of
      which was estimated from the results of a collaborative assay carried out by 5
      laboratories in 4 countries. The wide variations in the results probably resulted
      from difficulties experienced in handling the first international standard. The
      potency finally agreed upon by the collaborating laboratories, on the basis of
      the overall mean values obtained after rejection of the most discrepant assays,
      was 8 403 IU/mg. That value was accepted by the WHO Expert Committee on
      Biological Standardization (1970), which consequently defined the International
      Unit of polymyxin B as the activity contained in 0.000119 mg of the second
      international standard.

PMID- 4350878
TI  - Intraaortic balloon pumping for ventricular septal defect or mitral regurgitation
      complicating acute myocardial infarction.

PMID- 4350879
TI  - Effects of infections on pregnancy risk.

PMID- 4350880
TI  - Antibody tests in streptococcal pharyngitis. Streptozyme versus conventional
      methods.

PMID- 4350881
TI  - Labial fusion: a cause of recurrent urinary tract infections.

PMID- 4350882
TI  - Differentiation of human cortical neurons: proteins of subcellular particles.

PMID- 4350883
TI  - [Contribution of stimulation and detection electrodiagnosis in the study and
      evaluation of long term peripheral nerve lesions].

PMID- 4350884
TI  - The kinetics of transmitter release in myasthenia gravis. I. An
      electrophysiological analysis of the storage of transmitter.

PMID- 4350885
TI  - Stepwise accumulation of autoregulated enzyme activities during the cell cycle of
      the eucaryote Chlorella.

PMID- 4350886
TI  - Enhancement of senescence in low passage human embryonic lung cells by an agent
      extracted from phase 3 cells.

PMID- 4350887
TI  - The effect of photosensitizing dyes on the  3 H-tymidine incorporation of cells
      growth in vitro.

PMID- 4350888
TI  - Myogenic cells derived from murine sarcoma virus induced mouse tumours: DNA
      synthesis and the effects of Simian virus 40 infection.

PMID- 4350889
TI  - Activation of nuclear chromatin and the release from contact-inhibition of 3T3
      cells.

PMID- 4350890
TI  - Maturation-stimulating effect of brain extract and dibutyryl cyclic AMP on
      dissociated embryonic brain cells in culture.

PMID- 4350891
TI  - Citric acid-sonication method for the isolation of nucleoli.

PMID- 4350892
TI  - Deoxyribonuclease in sea urchin embryos. Comparison of the activity present in
      developing embryos, in nuclei, and in mitochondria.

PMID- 4350893
TI  - Differential sensitivity of antigen- and mitogen-stimulated human leucocytes to
      prolonged inhibition of potassium transport.

PMID- 4350895
TI  - Phosphatases from rice bran.

PMID- 4350896
TI  - Inhibition of hexosephosphate aminotransferase activity in vitro by tolbutamide.

PMID- 4350894
TI  - Semipermeable membranes for improving the histochemical demonstration of enzyme
      activities in tissue sections. 3. Lactate dehydrogenase.

PMID- 4350897
TI  - Studies on L-glycerol-3-phosphate dehydrogenases in Japanese Quail, Coturnix
      coturnix japonica. II. Comparison of activity of mitochondrial and cytoplasmic L
      glycerol-3-phosphate dehydrogenases in testes and liver of developing male
      Japanese quail.

PMID- 4350898
TI  - DNA-dependent RNA polymerase from Ehrlich ascites tumor cells. I. Partial
      purification and characterization of RNA polymerase II.

PMID- 4350901
TI  - Synthetic analogues of polynucleotides. IX. Synthesis of 3'-O-carboxymethyl-2'
      deoxyribonucleosides and their use in the synthesis of an analogue of 2'
      deoxyadenylyl-(3' leads to 5'-)-thymidine 3'-phosphate.

PMID- 4350900
TI  - The crystal structure of bonito (Katsuo) ferrocytochrome c at 2.3 A resolution.

PMID- 4350899
TI  - Biochemical studies on sulfate-reducing bacteria. XII. Some properties of
      flavodoxin from Desulfovibrio vulgaris.

PMID- 4350902
TI  - The influence of silica gel G on the quantitative analysis of lipid phosphorus.

PMID- 4350904
TI  - Fine-structural aspects of macrogametogenesis in Eimeria magna.

PMID- 4350903
TI  - Effects of liothyronine-induced hypermetabolism on dipyrone metabolism in man.

PMID- 4350905
TI  - The effects of actinomycin D, gibberellin A7, and cyclic AMP on mating of
      Chlamydomonas reinhardtii.

PMID- 4350906
TI  - [Intracellular localization and characterization of 2 types of malate
      dehydrogenases in Trichomonas vaginalis Donne, 1836].

PMID- 4350907
TI  - Growth phase and the number of phosphorylation sites in the mitochondrial
      electron transport chain of Acanthamoeba castellanii.

PMID- 4350908
TI  - Current therapy of Wilms' tumor.

PMID- 4350909
TI  - Juvenile nasopharyngeal angiofibroma.

PMID- 4350910
TI  - [Advances in pulmonology. Theoretical bases for the use of bronchodilator
      agents].

PMID- 4350911
TI  - Otoneurology.

PMID- 4350912
TI  - Peripheral nerve surgery.

PMID- 4350913
TI  - General neurophysiology: bioelectric aspects.

PMID- 4350914
TI  - Regional physiology of the nervous system.

PMID- 4350915
TI  - Neuropathology.

PMID- 4350916
TI  - Clinical neurology.

PMID- 4350917
TI  - Effect of REM sleep deprivation on electric shock threshold in rats.

PMID- 4350918
TI  - [Hypsarrhythmia and synthetic ACTH].

PMID- 4350919
TI  - [Reactivity of the hypothalamo-hypophyseal-adrenal system of the guinea pig in
      relation to age].

PMID- 4350920
TI  - Some aspects of nucleoside and nucleotide metabolism in the peripheral leukocytes
      during kidney allograft rejection.

PMID- 4350922
TI  - Correlations between some economic, social and infectious factors and the
      pathology of pregnancy and of the neonate.

PMID- 4350921
TI  - [The use of the gel immunoelectrodiffusion method in the rapid diagnosis of
      smallpox in man].

PMID- 4350923
TI  - Comparative studies on some herpes simplex virus strains with different
      locations. II. Study of the virulence character.

PMID- 4350924
TI  - The action of human immunoglobulins in experimental herpes infection in the
      newborn rat.

PMID- 4350925
TI  - [Pulmonary hemangiopericytomas (apropos of 3 cases)].

PMID- 4350926
TI  - Atherosclerosis and the arterial smooth muscle cell: Proliferation of smooth
      muscle is a key event in the genesis of the lesions of atherosclerosis.

PMID- 4350927
TI  - Slow viruses: role in persistent disease.

PMID- 4350928
TI  - Postlesion axonal growth produces permanent functional connections.
AB  - Lesions of the entorhinal cortex in neonatal rats cause the commissural
      projections to the dentate gyrus to spread from their normal location in the
      inner molecular layer into the outer molecular layer, a region normally occupied
      by afferents from the entorhinal cortex. These lesions also cause the short
      latency response to commissural stimulation to spread into the outer molecular
      layer, a result suggesting that these abnormally located connections are
      operative.

PMID- 4350929
TI  - Delta 9 -tetrahydrocannabinol and ethanol: differential effects on sympathetic
      activity in differing environmental setting.
AB  - Serum dopamine beta-hydroxylase activity, a useful biochemical index of
      peripheral sympathetic nervous activity, was measured in rats treated with
      Delta(9)-tetrahydrocannabinol or ethanol or both substances. After 7 days of
      treatment with either substance, serum dopamine beta-hydroxylase activity
      decreased significantly. Combined treatment with both agents enhanced the effects
      of each given alone. In rats subjected to immobilization stress, treatment with
      Delta(9)- tetrahydrocannabinol appeared to potentiate the stress-induced increase
      in serum enzyme activity. Treatment with ethanol, with or without Delta(9)
      tetrahydrocannabinol, effectively blocked this increase in enzyme activity. These
      results show that both substances have significant effects on the sympathetic
      nervous system which are critically influenced by environmental setting.

PMID- 4350930
TI  - Angiotensin-sodium interaction in blood pressure maintenance of renal
      hypertensive and normotensive rats.
AB  - A specific inhibitor of angiotensin II was used in rats to investigate whether
      angiotensin is involved in the maintenance of blood pressure in one-kidney
      Goldblatt hypertension, in which plasma renin levels are not usually increased.
      The inhibitor produced marked falls in blood pressure, often down to normal
      levels in the hypertensive animals only when they were depleted in sodium and not
      after sodium repletion. Much lesser but still significant falls in blood pressure
      were also produced in normotensive sodium-depleted rats but not in repleted rats.
      We conclude that the importance of angiotensin for maintaining blood pressure is
      largely determined by its relation to available sodium or fluid volume, since the
      renin component in maintenance of either the hypertensive or the normotensive
      state could be exposed only by sodium deprivation. Therefore, volume expansion
      per se or other pressor factors may be involved in maintaining blood pressure of
      these sodium-replete normotensive or hypertensive animals.

PMID- 4350931
TI  - [Change in brain alkaline and acid phosphatase activity under the action of
      adrenocorticotrophic hormone and hydrocortisone in experimental transplanted
      cancer of the rat mammary gland].

PMID- 4350932
TI  - [Effect of methylmercaptoimidazole on the enzyme activity in the myocardium of
      normal and thyroidectomized guinea pigs].

PMID- 4350934
TI  - [Detection and some properties of Pichia guillermondii phosphatases that
      hydrolyze flavin mononucleotide].

PMID- 4350933
TI  - [Effect os serotonin and calcium on the cyclic 3',5'-AMP level in the smooth
      uterine muscle and in other rabbit tissues].

PMID- 4350935
TI  - The effect of iodine prophylaxis on the incidence of endemic cretinism.

PMID- 4350936
TI  - Effect of iodine correction early in fetal life on intelligence quotient. A
      preliminary report.

PMID- 4350937
TI  - Prophylaxis of endemic goiter with iodized oil in rural Peru.

PMID- 4350938
TI  - The optimal program for prophylaxis of endemic goiter with iodized oil.

PMID- 4350939
TI  - IQ tests and intelligence in endemic cretinism.

PMID- 4350940
TI  - Tetrahydroisoquinoline alkaloids: uptake, storage, and secretion by the adrenal
      medulla and by adrenergic nerves.

PMID- 4350941
TI  - Experimental study of sleep in chronic alcoholics before, during, and after four
      days of heavy drinking with a nondrinking comparison.

PMID- 4350942
TI  - The effects of alcohol on dreams and hallucinations in alcohol addicts.

PMID- 4350943
TI  - Certain validity problems in computer analysis of clinical EEGS.

PMID- 4350944
TI  - Electroencephalographic and other evidence for mixed depressant and stimulant
      actions of alcoholic beverages.

PMID- 4350945
TI  - Recent studies in man and animal of peripheral nerve and muscle dysfunction
      associated with chronic alcoholism.

PMID- 4350946
TI  - [Heterogeneity of glycogenosis type VI. Study of leukocyte phosphorylase activity
      in 2 families].

PMID- 4350947
TI  - [Critical study of hypophosphatemia for genetic study of familial
      hypophosphatemic vitamin-resistant rickets].

PMID- 4350948
TI  - Seryl transfer ribonucleic acid synthetase of Escherichia coli B. Purification,
      subunit structure, and behavior in the acylation reaction.

PMID- 4350949
TI  - Seryl transfer ribonucleic acid synthetase of Escherichia coli B, Enzyme
      substrate interactions.

PMID- 4350950
TI  - Characterization and poly(adenylic acid) content of Ehrlich ascites cell
      ribonucleic acids fractionated on unmodified cellulose columns.

PMID- 4350951
TI  - Two physically and functionally distinct forms of eukaryotic 40S ribosomal
      subunits.

PMID- 4350952
TI  - A filter assay for steroid hormone receptors.

PMID- 4350953
TI  - Phospholipid biosynthesis in the membranes of immature and mature red blood
      cells.

PMID- 4350954
TI  - Oxidation of 3,3'-diaminobenzidine by rat liver mitochondria.

PMID- 4350956
TI  - Thorotrast-induced hepatoma presenting as hyperparathyroidism.

PMID- 4350955
TI  - Lipid model membranes. Characterization of mixed phospholipid vesicles.

PMID- 4350957
TI  - Radiation-induced extraskeletal osteosarcoma.

PMID- 4350958
TI  - Ultrastructure of bronchial oncocytoma.

PMID- 4350959
TI  - Structure and size prognosis in nephroblastoma.

PMID- 4350961
TI  - [Radioimmunoassay of plasma renin activity--comparison with biological method
      (improved Skinner's method)].

PMID- 4350960
TI  - Oat cell carcinoma of the pancreas with ectopic ACTH secretion.

PMID- 4350962
TI  - [Case of hepatoblastoma in an infant with ectopic gonadotropin production].

PMID- 4350963
TI  - [Effects of continuous administration of ACTH on the function of the adrenal
      cortex and pituitary body].

PMID- 4350964
TI  - Cytoplasmic and mitochondrial NAD + -NADH 2  ratios in rat brain and liver:
      effect of hypoxia.

PMID- 4350965
TI  - An electrophoretic study of some hydrolases from an OP-susceptible and an OP
      resistant strain of the green peach aphid, Myzus persicae (Sulz.).

PMID- 4350966
TI  - Enhancement of potassium influx, in baby hamster kidney cells and chicken
      erythrocytes, during adsorption of parainfluenza 1 (Sendai) virus.

PMID- 4350967
TI  - Phosphatidylinositol metabolism in cells receiving extracellular stimulation.

PMID- 4350968
TI  - Formation of 2,3-pentanediol from 2,3-pentanedione and acetylethylcarbinol by
      diacetyl(acetoin)reductase from Aerobacter aerogenes. A possible new pathway.

PMID- 4350969
TI  - DNA synthesis in isolated nuclei and isolated mitochondria of herpes simplex
      virus infected HeLa cells.

PMID- 4350970
TI  - Structural properties of the ligand binding sites of murine myeloma proteins.

PMID- 4350971
TI  - [Combination of glomus tumor of the esophagus and diaphragmatic hernia].

PMID- 4350972
TI  - The variable influence of host microflora and intercurrent infections on
      immunological competence and carcinogenesis.

PMID- 4350973
TI  - Specific killing of RSV-transformed cells in vitro by lymphoid cells from RSV
      tumor-bearing chickens.

PMID- 4350974
TI  - Analysis of cell membrane antigens using radioiodinated, purified antibodies. I.
      Solubilization and preliminary fractionation of membrane antigens of cells
      transformed by SV 40  virus.

PMID- 4350976
TI  - [Voice disorders of neurological or neuropsychiatric origin].

PMID- 4350975
TI  - Analysis of cell membrane antigens using radioiodinated, purified antibodies. II.
      A factor in the serum of hamsters bearing SV 40 -induced tumors which reacts with
      antibodies to SV 40 -transformed cell membranes.

PMID- 4350977
TI  - Measurement of plasma renin activity by angiotensin I radioimmunoassay. II.
      Clinical results.

PMID- 4350978
TI  - Nutritional effectiveness of 1,25-dihydroxycholecalciferol in preventing rickets
      in chicks.

PMID- 4350980
TI  - [Present status of drug-induced asthma].

PMID- 4350979
TI  - [Drug-induced pulmonary vascular accidents].

PMID- 4350981
TI  - [X-ray picture of the thyroid gland, especially lymphography of the thyroid
      gland, and its use for the diagnosis of cervical lymph node metastases].

PMID- 4350983
TI  - [The diagnosis of adenovirus infection in cattle].

PMID- 4350982
TI  - [Hypercalcemia as a complication in the hormonal treatment of carcinoma of the
      breast with metastases and the hormone activity of tumors].

PMID- 4350984
TI  - [Serological properties of enteroviruses isolated from swine].

PMID- 4350985
TI  - [Avian influenza (a survey of the literature)].

PMID- 4350986
TI  - Ultrastructure of the proximal convoluted tubules during repair following
      hormonally induced necrosis in rat kidney.

PMID- 4350988
TI  - Histochemical and ultrastructural investigation on the endocrine cells of the
      stomach in hypersecreting (pylorus-ligated) rats.

PMID- 4350987
TI  - Experimental Listeria cystitis. II. Further evidence of the epithelial phase in
      experimental Listeria infection. An electron microscopic study.

PMID- 4350989
TI  - Primary carcinoma of the extrahepatic bile ducts.

PMID- 4350990
TI  - Metastases and primary neoplasms of the stomach in patients with breast cancer.

PMID- 4350991
TI  - [Extraction of crystalline nuclear inclusions induced by type 5 adenovirus in KB
      cells].

PMID- 4350992
TI  - [Practical problems of the isolation and identification of staphylococci in the
      laboratory].

PMID- 4350993
TI  - Rabbit red cell cyclic AMP-dependent protein kinase. I. Reversible subunit
      interaction.

PMID- 4350994
TI  - Respiratory control and oxidative phosphorylation of the cytochrome c-cytochrome
      oxidase complex.

PMID- 4350995
TI  - A rapid method for the isolation of large quantities of rat liver parenchymal
      cells with high anabolic rates.

PMID- 4350996
TI  - Cortisol receptors in rabbit fetal lung.

PMID- 4350997
TI  - Purification of anthranilate 5-phosphoribosylpyrophosphate
      phosphoribosyltransferase from Salmonella typhimurium using affinity
      chromatography: resolution of monomeric and dimeric forms.

PMID- 4350998
TI  - Comparison of the Ca ++  requirement for the steroidogenic effect of ACTH acid
      dibutyryl cyclic AMP in rat adrenal cell suspension.

PMID- 4350999
TI  - Demonstration of a glycoprotein which is associated with a purified myelin
      fraction from rat brain.

PMID- 4351000
TI  - Contribution of "substrate shuttles" in hepatic alcohol metabolism in chronic
      alcoholism.

PMID- 4351001
TI  - Mitochondrial DNA and glucose repression in yeast.

PMID- 4351003
TI  - Mossbauer effect in bacterial catalase.

PMID- 4351002
TI  - Chain reversals in proteins.

PMID- 4351004
TI  - A hydrogen-deuterium exchange study of membranous cytochrome oxidase.

PMID- 4351005
TI  - Turbidimetric estimation of chylomicrons and very low density lipoproteins in
      human sera after precipitation by sodium lauryl sulfate.

PMID- 4351006
TI  - [Incidence of some brain tumors with various localization in relationship to the
      relative size of brain lobes].

PMID- 4351007
TI  - [Effect of chemical compounds of varying toxicity on the free-radical content and
      microsomal system of multifunction oxidases in animal liver].

PMID- 4351008
TI  - Electron microscopic evidence of the subviral oncogenic particles (virosomes)
      isolated from the mitochondria of Rous sarcoma cells.

PMID- 4351009
TI  - [Some histochemical aspects of the oogenesis of Betta splendens R. (Teleostean
      Anabantide)].

PMID- 4351010
TI  - The influence of in vivo administered chloramphenicol and oxytetracycline on some
      mitochondrial enzymes of rat-small-intestinal epithelium: histochemical data.

PMID- 4351011
TI  - Status of credentialing for health personnel.

PMID- 4351012
TI  - Regulation of cyclic AMP levels and aggregation in human platelets by
      prostaglandin E   .

PMID- 4351013
TI  - Monolayer cell culture of neonatal rat pancreas: an ultrastructural and
      biochemical study of functioning endocrine cells.

PMID- 4351014
TI  - The structures of the principal glycerolipids of pig liver.

PMID- 4351016
TI  - Case records of the Massachusetts General Hospital. Weekly clinicopathological
      exercises. Case 28-1973.

PMID- 4351015
TI  - Autopsy findings in a long-surviving liver recipient.

PMID- 4351017
TI  - [Cytotoxic stimulation of steroid hormone formation in blockade of various types
      of RNA].

PMID- 4351018
TI  - [Characteristics of the blastomogenesis induced by tryptophan metabolites].

PMID- 4351019
TI  - Epidemiology of slipped capital femoral epiphysis: a review of the literature.

PMID- 4351021
TI  - [Orbital cylindroma].

PMID- 4351020
TI  - Revolutions and cyclical rhythms in prenatal life: fetal respiratory movements
      rediscovered.

PMID- 4351022
TI  - [Granular cell myoblastoma of the tongue].

PMID- 4351023
TI  - [Pulmonary adenomatosis].

PMID- 4351024
TI  - Interstitial pneumonia and cytomegalovirus infection as complications of human
      marrow transplantation.

PMID- 4351025
TI  - A simple method for evaluating the immunosuppressive potency of antimouse
      lymphocytic serum.

PMID- 4351026
TI  - [Thiamine-S 35  binding by the liver mitochondria of white rats in in vitro
      experiments].

PMID- 4351027
TI  - [Lysyl-tRNA-synthetase from E. coli B: the isolation and properties of 2
      enzymatically active forms].

PMID- 4351028
TI  - [Lipid content in dog lung tissue].

PMID- 4351029
TI  - [Organization of the afferent connections of the cerebellar cortex].

PMID- 4351030
TI  - [Role of the analyzers in systemic activity].

PMID- 4351031
TI  - [Diagnosis of the neoplasms of islands of Langerhans].

PMID- 4351032
TI  - Histological and ultrastructural studies of the basal disk of Hydra. II. Nerve
      cells and other epithelial cells.

PMID- 4351033
TI  - Cochlear pathology in viral disease.

PMID- 4351034
TI  - Spiral ganglion virus-like particles of guinea pigs. Further observations.

PMID- 4351035
TI  - Clinical studies in sudden deafness.

PMID- 4351036
TI  - The role of viruses in sudden deafness.

PMID- 4351037
TI  - Clinical measures of 8th nerve function.

PMID- 4351038
TI  - Behavioral studies of noise-induced hearing loss in primates: loudness
      recruitment.

PMID- 4351040
TI  - [Malignant hepatoma with amenorrhea and galactorrhea. Disappearance of the
      endocrine syndrome following right hepatectomy].

PMID- 4351039
TI  - [Angioorganopathy--ischemic neuropathy. An electromyographic study].

PMID- 4351041
TI  - Public policy toward environment 1973: a review and appraisal. The seabed.

PMID- 4351042
TI  - [Preliminary study of puberty in girls in Dakar. Longitudinal study of 110
      African adolescents].

PMID- 4351043
TI  - [Synthesis and antiviral effects of adamantan derivatives].

PMID- 4351044
TI  - Thermal enhancement of DNA damage by an alkylating agent in human cells.

PMID- 4351045
TI  - The role of superoxide and singlet oxygen in lipid peroxidation promoted by
      xanthine oxidase.

PMID- 4351046
TI  - Resonance Raman spectroscopy of cytochrome c oxidase and electron transport
      particles with excitation near the Soret band.

PMID- 4351047
TI  - Translation of AKR-murine leukemia viral RNA in an E. coli cell-free system.

PMID- 4351048
TI  - Pituitary hormone releasing or inhibiting activity of metal ions present in
      hypothalamic extracts.

PMID- 4351049
TI  - Action of methanol on the assocation of ribosomal subunits and its effect on the
      GTPase activity of elongation factor G.

PMID- 4351050
TI  - CRF-stimulated biosynthesis of ACTH in a cell-free system from rat anterior
      pituitaries.

PMID- 4351052
TI  - Simian virus 40 rapidly lowers cAMP levels in mouse cells.

PMID- 4351051
TI  - Effect of pyrimidine and ribose modifications on the antiviral activity of
      synthetic polynucleotides.

PMID- 4351053
TI  - The principal glucocorticoid binding macromolecule in hepatoma cells in culture
      is similar to corticosteroid binder II of rat liver cytosol.

PMID- 4351055
TI  - Detection of three kinetic phases in the thermal unfolding of ferricytochrome c.

PMID- 4351054
TI  - Inhibition of ACTH-stimulated steroidogenesis in isolated rat adrenal cells
      treated with neuraminidase.

PMID- 4351056
TI  - Thermodynamic studies of the opening of the heme crevice of ferricytochrome c.

PMID- 4351057
TI  - Effects of insulin, epinephrine, and cyclic adenosine monophosphate on pyruvate
      dehydrogenase of adipose tissue.

PMID- 4351058
TI  - On the complexation of ferric ions by reduced nicotinamide adenine dinucleotide.

PMID- 4351059
TI  - Lateral phase separation in phospholipid membranes.

PMID- 4351060
TI  - Amino acid sequence of a cyanogen bromide cleavage peptide from hens egg
      phosvitin.

PMID- 4351061
TI  - Proton spin lattice relaxation time measurements at 90MHz and 270 MHz.

PMID- 4351062
TI  - Lactate dehydrogenase: electrophoretic behaviour, electron microscopy and
      structure.

PMID- 4351063
TI  - Isolectins from wax bean with differential agglutination of normal and
      transformed mammalian cells.

PMID- 4351065
TI  - Significance of upward gaze palsy (Parinaud's syndrome) in hydrocephalus due to
      shunt malfunction.

PMID- 4351064
TI  - Anion-binding and the state of copper in caeruloplasmin.

PMID- 4351067
TI  - Synthesis of cholesterol in hypercholesterolemia and its relationship to plasma
      trigylcerides.

PMID- 4351066
TI  - Virological investigations in chronic prostatitis.

PMID- 4351068
TI  - [Viral etiology of human laryngeal papilloma: morphological demonstration of a
      papovavirus].

PMID- 4351069
TI  - Clostridia. Ubiquitous and still lethal.

PMID- 4351070
TI  - [Results of the surgical treatment of malignant liver tumors].

PMID- 4351071
TI  - [6 cases of poliomyelitis associated with oral immunization].

PMID- 4351072
TI  - [Occurrence of blue sclera during mental diseases and its causes].

PMID- 4351073
TI  - Investigation of procedures for subcellular fractionation of rabbit aortic
      tissue.

PMID- 4351074
TI  - Studies on the de novo biosynthesis of NAD in Escherichia coli. V. Properties of
      the quinolinic acid synthetase system.

PMID- 4351075
TI  - Stimulation of sensitivity of the glycogen phosphorylase-converting system in
      skeletal muscle by metabolic inhibitors.

PMID- 4351076
TI  - Concanavalin A as a probe of phosphomannan molecular structure.

PMID- 4351077
TI  - Quantum chemical study of the mechanism of collagen proline hydroxylation.

PMID- 4351078
TI  - Factors affecting the synthesis and release of the extracellular protease of
      Aspergillus oryzae NRRL 2160.

PMID- 4351079
TI  - Basal and hormone-stimulated adenylate cyclase in liver plasma membranes:
      measurement by radioimmunoassay of cyclic AMP.

PMID- 4351080
TI  - Cyclic nucleotide phosphodiesterase activity in the plasma and erythrocytes of
      normal and diabetic rats.

PMID- 4351081
TI  - Polysaccharides of SV 40-transformed green monkey kidney cells.

PMID- 4351082
TI  - Cerebral amino acids of rats deprived of paradoxical sleep.

PMID- 4351083
TI  - The effect of placebo and drugs on human sleep.

PMID- 4351084
TI  - The distribution of free myo-inositol in fluids, spermatozoa, and tissues of the
      bull genital tract and observations on its uptake by the rabbit epididymis.

PMID- 4351085
TI  - [Endocrine exophthalmos].

PMID- 4351086
TI  - Calcium transport through carbon tetrachloride solutions of vitamin D 3 .

PMID- 4351087
TI  - Mastocalcergy in the mouse.

PMID- 4351088
TI  - The early ambulation of patients after myocardial infarction.

PMID- 4351089
TI  - [Endogenous uveitis in childhood].

PMID- 4351090
TI  - A study of the direct o-toluidine blood glucose determination.

PMID- 4351092
TI  - Inhibitors of the growth and aggregation of calcium oxalate crystals in vitro.

PMID- 4351091
TI  - A stable plasma lipoprotein and lecithin cholesterol acyltransferase control
      material.

PMID- 4351094
TI  - Glycogen metabolism in human hormone-producing trophoblastic cells in continuous
      culture--II. Characterization of BeWo glycogen phosphorylase.

PMID- 4351093
TI  - Increased bone formation in rabbits following intravenous and intra-osseous
      injection of zinc beryllium silicate.

PMID- 4351095
TI  - Rhythmic heart rate variability (sinus arrhythmia) related to stages of sleep.

PMID- 4351096
TI  - Difficulties of the differential diagnosis in a medulloblastoma. A casuistic
      contribution.

PMID- 4351097
TI  - [Indole group alkaloids and indole derivatives in various species of periwinkle].

PMID- 4351098
TI  - The adnormal biochemistry of inherited disorders of lipid metabolism.

PMID- 4351099
TI  - Metabolic oscillations and food intake.

PMID- 4351100
TI  - Current enigmas in cancer research.

PMID- 4351101
TI  - Genetic control of melanin metabolism within the melanin unit of mammalian
      epidermis.

PMID- 4351102
TI  - Dermatoglyphics.

PMID- 4351103
TI  - Ophthalmologic, biochemical, platelet, and ultrastructural defects in the various
      types of oculocutaneous albinism.

PMID- 4351105
TI  - Primary glioblastoma multiforme of the spinal cord in infancy and childhood.

PMID- 4351104
TI  - The inheritance of psoriasis.

PMID- 4351106
TI  - Divalent ion metabolism and the kidney.

PMID- 4351107
TI  - Combination chemotherapy in the treatment of advanced Hodgkin's disease.

PMID- 4351108
TI  - A possible relationship between persistent hepatitis B antigenaemia and renal
      disease in Southern African Bantu.

PMID- 4351109
TI  - The paricipation of phospholipids in the extrinsic pathway of the coagulation
      process.

PMID- 4351110
TI  - [Seasonal rhythms in the functioning of the endocrine system of hibernating
      mammals].

PMID- 4351111
TI  - [Sleep disorders with erection].

PMID- 4351112
TI  - [Therapy of warts using nitrogen and salicylic acid controlled by electron
      microscopy].

PMID- 4351113
TI  - [The concentration of various microelements and the activity of a series of
      oxidative enzymes in the blood and osseous tissue of patients with chronic
      suppurative otitis].

PMID- 4351114
TI  - [Detection and treatment of extra-organic tumors of the neck].

PMID- 4351115
TI  - Comparison of equivalent spherical volume and aerodynamic diameters for
      irregularly shaped particles.

PMID- 4351117
TI  - Gastrointestinal neuropathy in familial amyloidosis. Report of a case with severe
      diarrhea without steatorrhea or malabsorption.

PMID- 4351116
TI  - Oral fat tolerance studies in chronic pancreatitis.

PMID- 4351119
TI  - Microbiological assay of purines.

PMID- 4351118
TI  - A rapid and sensitive assay for pyrimidine dimers in DNA.

PMID- 4351120
TI  - A method of measuring protein dry weight in solutions of unknown salt
      concentration and an application to lipoproteins.

PMID- 4351121
TI  - A sensitive mechanized determination of ATP+ADP.

PMID- 4351122
TI  - Recommendations concerning the use of bacterial collagenase for isolating
      collagen-associated molecules from tissues.

PMID- 4351123
TI  - An enzymatic cycling method for nicotinamide-adenine dinucleotide with malic and
      alcohol dehydrogenases.

PMID- 4351124
TI  - Autoimmune progesterone dermatitis of pregnancy.

PMID- 4351125
TI  - Contraceptive conundrum. II. Hypertension.

PMID- 4351126
TI  - The quest for instant mental health.

PMID- 4351127
TI  - [Various features of the ultrastructure of cerebral cortex macroglial cells].

PMID- 4351128
TI  - [Typification and sources of development of nerve cells].

PMID- 4351130
TI  - [Muscular blood flow during inhibition of 3', 5'-AMP-phosphodiesterase. Clinical
      and experimental studies using 3,7-dimethyl-1-(5-oxo-hexyl)-xanthine].

PMID- 4351129
TI  - [Posttraumatic endothelial histogenesis].

PMID- 4351131
TI  - [Adrenocorticotropic effect of beta-1-23-corticotropin compared with beta-1-24
      corticotropin].

PMID- 4351132
TI  - An investigation of viral and bacterial agents associated with ovine perinatal
      mortality.

PMID- 4351133
TI  - Australian exotic animal disease control plans.

PMID- 4351134
TI  - Inhibition by avidin of the ATP-Pi enchange activities associated with
      preparations of energy transfer factors A and A-D.

PMID- 4351135
TI  - Inability of detect cyclic AMP in vegetative or sporulating cells or dormant
      spores of Bacillus megaterium.

PMID- 4351136
TI  - Structure of the flavin site of Chromatium flavocytochrome c -552 .

PMID- 4351137
TI  - Irreversible inhibition of ribonucleotide reductase from Ehrlich tumor cells by a
      modulator analog.

PMID- 4351138
TI  - Substrate specificity of glycogen synthase phosphatase from bovine heart: action
      on phosphorylase a and histone.

PMID- 4351139
TI  - Stability and function of mengovirus RNA in cell-free protein synthesis.

PMID- 4351140
TI  - Loss of hepatoma ribosomal RNA during warfarin therapy.

PMID- 4351141
TI  - The fully-active nature of synthetic and hydrolytic activities of glucose-6
      phosphatase of intact nuclear membrane.

PMID- 4351142
TI  - Glucose metabolism in mixed glioblastoma and neuroblastoma cultures.

PMID- 4351143
TI  - Kinetics of poliovirus replication in HeLa cells infected by isolated RNA.

PMID- 4351145
TI  - A study of transfer RNA methylation.

PMID- 4351144
TI  - Analysis of a crosslinked peptide from calf bone collagen: evidence that
      hydroxylysyl glycoside participates in the crosslink.

PMID- 4351146
TI  - Kinetics of synthesis of cytochromes a and a 3  during respiratory adaptation of
      yeast.

PMID- 4351147
TI  - K + -stimulated ATPase in purified microsomes of bullfrog oxyntic cells.

PMID- 4351148
TI  - Rheologic hysteresis curve shape specificity of mixed lipid films.

PMID- 4351149
TI  - Pure and mixed monomolecular films of 12-nitroxide stearate.

PMID- 4351150
TI  - SH-groups on the surface of pancreas cells involved in secretin stimulation and
      glucose-mediated secretion.

PMID- 4351151
TI  - Effects of glucagon, 3',5'-AMP and 3',5'-GMP on ion fluxes and transmembrane
      potential in perfused livers of normal and adrenalectomized rats.

PMID- 4351152
TI  - Aminoacyl transfer RNA formation. 3. Mechanism of aminoacylation stimulated by
      polyamines.

PMID- 4351153
TI  - Synthesis and properties of an alternating polydeoxynucleotide containing 4
      thiodeoxyuridine: poly (d(A S 4 U)-d(A-S 4 U)).

PMID- 4351155
TI  - [Brief report of sanitary conditions and methods of prophylaxis applied in Ivory
      Coast].

PMID- 4351154
TI  - [Current status of husbandry developmental projects in Ivory Coast, notably those
      concerning the creation of disease-free zones].

PMID- 4351156
TI  - [Rules of sanitary policy for animals in Ivory Coast].

PMID- 4351157
TI  - Preparation and properties of phosphatidal ethanolamine from bovine white matter.

PMID- 4351158
TI  - Spin labeled lipid probes in serum lipoproteins.

PMID- 4351159
TI  - Two forms of microsomal palmitoyl-coenzyme A synthetase.

PMID- 4351160
TI  - The free lipids of Brucella melitensis and Bordetella pertussis.

PMID- 4351161
TI  - The kinetics of the redox reactions of ubiquinone related to the electron
      transport activity in the respiratory chain.

PMID- 4351162
TI  - [Structural and mechanical properties of aerosil-stabilized liniments].

PMID- 4351163
TI  - Liver scintiphotography as an index of liver abnormality.

PMID- 4351164
TI  - In vivo neutron activation analysis for calcium in man.

PMID- 4351165
TI  - Intravenous perchlorate in brain scanning: effects on choroid plexus and lesion
      visibility.

PMID- 4351167
TI  - [The value of avafortan in a general surgery service].

PMID- 4351166
TI  - Embryonal rhabdomyosarcoma of the head and neck in children.

PMID- 4351168
TI  - [Distribution of I-131 labeled somatotropic and adrenocorticotropic hormones and
      their conjugates with alkylating compounds in rats].

PMID- 4351169
TI  - Frequent association of IgMlambda with crystalline inclusions in chronic
      lymphatic leukemic lymphocytes.

PMID- 4351170
TI  - Herpetic manifestations.

PMID- 4351171
TI  - Comparison of nucleolar proteins of normal rat liver and Novikoff hepatoma
      ascites cells by two-dimensional polyacrylamide gel electrophoresis.
AB  - A two-dimensional polyacrylamide gel electrophoresis technique is presented for
      separation of acid-extracted proteins of isolated nucleoli of normal rat liver
      and Novikoff hepatoma ascites cells. About 100 distinct protein spots were
      resolved. Comparison of the patterns for normal liver and Novikoff hepatoma
      revealed nine spots with markedly different intensities in the two patterns. Two
      spots were found that were unique to the normal liver pattern, and one spot was
      found that was unique to the hepatoma pattern.

PMID- 4351172
TI  - Genetic control of development in Volvox: isolation and characterization of
      morphogenetic mutants.
AB  - Morphogenetic mutants of the colonial green alga, Volvox carteri f. nagariensis,
      were induced by chemical mutagenesis. The 68 independent mutants are classified
      into 12 readily identifiable phenotypes affecting various stages of asexual
      development. Nine of the mutants are temperature sensitive with normal
      development at 25 degrees and mutant development occurring at 35 degrees . Some
      mutant genes appear to be involved in the regulation of differentiation or the
      stability of the differentiated state. Other mutations occur in genes apparently
      responsible for structural components of dividing cells or adult colonies. Two
      mutants affect different aspects of the posterior-anterior polarization of the
      mature colony. One mutation affects a gene which acts very early in colonial
      development, but affects the appearance of the mature colony. The mutants
      isolated demonstrate the feasibility of using Volvox to study the genetic control
      of early steps in embryogenesis.

PMID- 4351173
TI  - Sequence homology at the 5'-termini of insect messenger RNAs.
AB  - Treatment of insect polyribosomes with 1 M KCl released a messenger
      ribonucleoprotein with a pronounced 16S peak. Phenol extraction resulted in a
      defined peak of 10S RNA, which was judged as mRNA by the following criteria: it
      showed specificity for binding to ribosomes, and the formation of initiation
      complex was dependent on protein initiation factors, GTP, mRNA, and aminoacyl
      tRNA. The complex directed protein synthesis upon the addition of elongation
      factors. mRNA was treated with phosphatase and phosphorylated at the 5'-end with
      [(32)P]cyanoethylphosphate. [(32)P]mRNA was digested by T1 ribonuclease to
      completion and chromatographed on DEAE-cellulose. The only fragment with (32)P
      was 15 nucleotides long; it was treated with pancreatic ribonuclease and
      fingerprinted. Fractions of AC, AAC, and AAAC were found. Initiation signal AUG
      or GUG in these mRNAs does not begin immediately at the 5'-end and may be at a
      distance greater than 15 nucleotides. Alkaline hydrolysis of mRNAs labeled in
      vivo with [(14)C]adenosine revealed Ap and pppAp. Alkaline hydrolysis of mRNA
      labeled with (32)P at the 5'-terminus resulted in pAp. Hence, these results
      suggest that in a heterogeneous population of mRNAs from insects, all start with
      A and have sequence homology at the 5'-termini. This sequence may reflect the
      signal for RNA polymerase on the gene or may promote the binding of mRNA to
      ribosomes.

PMID- 4351174
TI  - Cell-free synthesis of procollagen: L-929 fibroblasts as a cellular model for
      dermatosparaxis.
AB  - A cell-free system that actively synthesizes collagen was prepared from L-929
      fibroblasts. Chromatographic and electrophoretic techniques were used to
      demonstrate that the only collagenous products are pro alpha(1) and pro alpha(2)
      chains. The collagen synthesized by the cell-free system was also compared to the
      collagen extracted from the cells. The cellular collagen was composed of
      aggregates of pro-alpha chains, while no alpha chains were found. Procollagen
      peptidase activity could not be detected in the cells, and the activity present
      in the medium was low, comparable to that in dermatosparaxic cell cultures. These
      properties indicate that L-929 cells may be a model system for dermatosparaxis.

PMID- 4351175
TI  - Stimulation of eukaryotic DNA-dependent RNA polymerase by protein factors.
AB  - Protein factors that stimulate DNA-dependent RNA polymerase activity in vitro
      have been purified from Novikoff ascites cells. These factors are not adsorbed by
      the diethylaminoethylcellulose column used for RNA polymerase purification and
      appear in the flow-through fraction. They can be fractionated into two classes by
      chromatography on carboxymethylcellulose. The first peak of activity elutes at
      0.1 M NH(4)Cl, is stable to heat treatment of 100 degrees for 5 min, and is
      designated heat-stable factor; the second peak of activity elutes at 0.3 M
      NH(4)Cl, is heat labile, and is designated heat-labile factor. Heat-labile factor
      can be further resolved into two components by chromatography on
      phosphocellulose. The heat-stable factor and second heat-labile factor stimulate
      the activity of (Novikoff ascites) RNA polymerase B by several-fold, and appear
      to function independently. RNA synthesis is stimulated only with native DNA as a
      template. No stimulation of Escherichia coli RNA polymerase is observed with any
      of the factors.

PMID- 4351176
TI  - Effect of insulin on the growth pattern and adenylate cyclase activity of BHK
      fibroblasts.
AB  - BHK 21/13 fibroblasts grown in the presence of insulin show some characteristics
      of a transformed strain. Cells broaden, cross each other intricately, and form
      colonies on both polystyrene dishes and soft agar. The effect of insulin is
      prevented by addition of N(6)-butyryl adenosine 3':5'-cyclic monophosphate and
      theophylline to the culture medium. Insulin causes a decrease in the
      concentration of intracellular adenosine 3':5'-cyclic monophosphate and
      inhibition of adenylate cyclase activity in BHK fibroblast membranes. This
      inhibition is observed at insulin concentrations of 0.1 nM or higher.

PMID- 4351177
TI  - Orientation and motion of amphiphilic spin labels in hexagonal lipid phases.
AB  - The acyl chain of spin-labeled fatty acids intercalates between the lipid
      hydrocarbon chains in hexagonal and micellar phases with the carboxyl group
      anchored at the lipid water interface. The spectra are characteristic of
      anisotropic motion and cannot be distinguished from the spectra of these probes
      in lamellar dispersions. In the hexagonal and micellar phases the molecular
      motion of the spin label increases as it is moved further away from the carboxyl
      group, similar to the behavior in the lamellar phase (Jost et al. (1971) J. Mol.
      Biol. 59, 77-98). The similarity in packing of the acyl chains in the hexagonal
      and lamellar phases suggests that localized regions of hexagonal phase are
      compatible with a bilayer matrix.

PMID- 4351178
TI  - Pleiotypic control by adenosine 3':5'-cyclic monophosphate: a model for growth
      control in animal cells.
AB  - The effects of serum deprivation on several general cellular biochemical
      processes ("pleiotypic response") related to the growth of normal fibroblasts can
      be mimicked by treatment of these cells with prostaglandin E(1) in the presence
      of serum. N(6),O(2)'-Dibutyryl adenosine 3':5'-cyclic monophosphate and
      theophylline inhibit the membrane transport processes without much effect on
      other pleiotypic reactions such as overall protein and RNA synthesis and protein
      degradation. The amount of intracellular cyclic AMP increases during serum
      starvation and returns to the initial concentration in unstarved cells when
      growth is initiated again upon addition of serum. Fibroblasts transformed by
      simian virus 40 have a lower cyclic AMP content than their untransformed parents.
      Serum deprivation neither increases cyclic AMP content nor significantly affects
      the pleiotypic reactions in transformed cells. Cycloheximide causes a decrease in
      cyclic AMP content of normal fibroblasts coincidentally with the ability of this
      inhibitor to stimulate uridine transport and slow protein degradation in cells
      deprived of serum.

PMID- 4351179
TI  - Determination of natural host taxonomy of RNA tumor viruses by molecular
      hybridization: application to RD-114, a candidate human virus.
AB  - The lysogenic bacteriophages and the RNA tumor viruses have in common the ability
      to add their genetic information to the genome of their host cells. The
      biological similarity extends further; data summarized here indicate that they
      both possess homology to the DNA of their uninfected indigenous hosts. Sharing of
      common sequences with normal host DNA has been established with avian, murine,
      feline, and primate oncornaviruses. This finding provides a method for
      determining the taxonomic position of the natural host of any new RNA tumor virus
      isolated. Application of this approach to RD-114 revealed extensive hybridization
      to normal cat DNA and little, if any, hybridization to human DNA. We conclude
      that the data assign a feline origin rather than a human origin to RD-114.

PMID- 4351181
TI  - A tumor antigen in tissue cultures derived from patients with Hodgkin's disease.
AB  - Pellets obtained from supernatant fluids of monolayer cultures of cells from
      patients with Hodgkin's disease were fractionated by isopycnic density
      sedimentation. Material in a peak of specific gravity 1.15-1.21 g/ml from two
      Hodgkin's disease cultures was used to immunize rabbits, and the antisera
      obtained in this manner were reacted by agar-gel diffusion and
      immunoelectrophoresis with antigens from the purified peaks and the
      unfractionated pellets of centrifuged culture medium from all the cultures. The
      antisera reacted with material from 9 of 10 lines derived from spleens of
      patients with Hodgkin's disease, 2 of 8 cell lines from histologically negative
      spleens from patients with Hodgkin's disease and with 3 of 6 lymphoma cell lines
      not diagnosed as Hodgkin's disease. The antisera did not react with 12 cell
      cultures prepared from normal adult and fetal spleen and thymus. The antigen from
      cultures from patients with Hodgkin's disease was not found in material
      sedimenting at lower specific gravities; it resisted Tweenether solubilization,
      and migrated as a single band by immunoelectrophoresis. The antigen was not found
      in disrupted, noncultured tumor cells from patients with Hodgkin's disease, and
      an antiserum against noncultured, minced tumor tissue did not react with the
      Hodgkin's disease tissue-culture material. No immunological relationship was
      found between the tissue culture antigen and Epstein-Barr, RD-114, or Rauscher
      murine leukemia viruses. The Hodgkin's disease antigen may be a tumorrelated
      antigen or a component of an oncogenic virus.

PMID- 4351180
TI  - Host-gene control of type-C RNA tumor virus expression and tumorigenesis in
      inbred mice.
AB  - We analyzed the relationship of genetic factors determining the expression of
      endogenous type-C RNA tumor viruses and other host-gene markers to tumorigenesis.
      A hybridization experiment was performed with mice of strains AKR/J and C57L, the
      first filial (F(1)) generation hybrids, the second filial (F(2)) generation
      hybrids, and the backcrosses to the two parental strains. The results
      demonstrated a highly significant and predictable association between the
      expression of complete infectious virus or the viral group-specific (gs) antigen
      in spleens of young mice and tumorigenesis later in life. Most of the tumors were
      thymic leukemia and reticulum sarcoma, but other mesenchymal, as well as
      epithelial, tumors were also observed. Tumors occurred preferentially in gs
      antigen- or virus-positive mice of all crosses; in the C57L-backcross and F(2)
      mice segregating for gs-antigen and virus expression, a few gs-antigen-negative
      mice developed reticulum cell sarcomas. At the time of their occurrence, the mice
      were all gs-antigen-positive, and most had virus as well.A minor effect of the
      major histocompatibility locus, H-2, on leukemogenesis was found in the F(2)
      mice. Several tumor types were also found that we have never observed in the two
      parental strains. Our data provide the most direct biological evidence in favor
      of the viral oncogene theory. Thus, from the presence or absence of expression in
      early life of splenic gs antigen or virus, we can predict whether or not a tumor
      is likely to develop later in life. These findings suggest that the genome of
      endogenous type-C RNA viruses is the major determinant for tumorigenesis although
      they provide no clues about the factors responsible for the various histological
      types.

PMID- 4351182
TI  - A quantitative assay for intercellular adhesion.
AB  - Intercellular adhesion is measured by a new method based on determination of the
      rates of attachment of single cells to confluent cell monolayers. The procedure
      is simple, rapid, and reproducible. Specific and nonspecific intercellular
      adhesions can be quantitated and distinguished from each other, and from the
      adhesion to glass (or plastic). The rate of adhesion of single cells to the
      monolayer is characteristic of more than 80% of the single-cell population. This
      method, therefore, provides a means for study of the molecular basis of
      intercellular adhesion.

PMID- 4351183
TI  - Conformations of diphosphopyridine coenzymes upon binding to dehydrogenases.
AB  - The binding of oxidized as well as reduced coenzyme to some dehydrogenases has
      been studied under different concentration ratios and temperatures by nuclear
      magnetic resonance spectroscopy. A significant difference in the spectral
      behavior between DPN(+) and DPNH upon binding is interpreted in terms of fast and
      slow on-off rates relative to the nuclear magnetic resonance time scale in the
      binding of these two coenzymes. Significant downfield shifts of DPN(+) were
      observed upon binding, comparable in magnitude to those expected upon opening
      (destacking) of the coenzymes in the case of chicken-muscle and lobster-tail
      lactate dehydrogenase (EC 1.1.1.27) and yeast alchol dehydrogenase (EC 1.1.1.1.).
      A preliminary survey of several other dehydrogenases is consistent with these
      findings. In the case of 3-phosphoglyceraldehyde dehydrogenase, there is a
      possibility that the coenzyme exists in the folded form.

PMID- 4351185
TI  - The fine structure of human lymph nodes under reactive conditions.

PMID- 4351184
TI  - Antigenic properties of endogenous type-C viruses from spontaneously transformed
      clones of BALB-3T3.
AB  - During long-term tissue culture of spontaneously transformed clones from BALB/c
      3T3 mouse-embryo cells, some clones spontaneously begin to produce high titers of
      endogenous murine type-C viruses. The antigenic properties of these viruses have
      been analyzed by indirect immunoelectronmicroscopy and can be classified into two
      distinguishable populations: (a) BALB/c murine myeloma-associated extracellular
      viruses that carry a specific envelope antigen, xVEA, different from the typical
      murine leukemia viral envelope antigens; and (b) previously uncharacterized type
      C viruses that have neither xVEA nor the murine leukemia viral envelope antigens.
      The former produces PC1 antigen and the latter might induce a new cell-surface
      antigen. Neither of these two populations of BALB/3T3 endogenous type-C viruses
      was able to infect BALB/c cells but both could infect NIH Swiss cells. A single
      BALB/3T3 clone, then, can release infectious endogenous type-C viruses with at
      least two different antigenic properties. We conclude that BALB/c somatic cells
      contain preexisting genetic information for production of at least closely
      related but, nevertheless, distinct type-C viruses.

PMID- 4351186
TI  - [Lipoatrophic diabetes. A case description].

PMID- 4351187
TI  - [Transcortin in health and disease].

PMID- 4351188
TI  - [Diagnostic value of serum ACTH in certain endocrine diseases].

PMID- 4351190
TI  - Autonomic defects in paralysis agitans and in the Shy-Drager syndrome.

PMID- 4351189
TI  - [Australia (SH) antigen and viral hepatitis (a survey of the literature)].

PMID- 4351191
TI  - Biochemical and pharmacological aspects of Parkinsonism.

PMID- 4351192
TI  - Cerebrocerebellar pathways. Anatomical data and some functional implications.

PMID- 4351193
TI  - Functional aspects of cerebellar signs in clinical neurology.

PMID- 4351194
TI  - On the possible role of cyclic AMP in the neuromuscular transmission and in the
      treatment of myasthenia gravis.

PMID- 4351195
TI  - Polyneuropathy caused by unknown universal intracellular deposits
      paraamyloidosis? Clinical, light microscopic and electron microscopic study.

PMID- 4351196
TI  - Clinical applications of hypothalamic-releasing factors.

PMID- 4351197
TI  - Clinical syndromes associated with EB virus infection.

PMID- 4351198
TI  - Viral hepatitis.

PMID- 4351199
TI  - Fine structure of acinar cells of human parotid gland.

PMID- 4351200
TI  - Metabolic activity during the degenerative and early regenerative stages of
      minced skeletal muscle.

PMID- 4351201
TI  - Regional variations in endoplasmic reticulum in the vas deferens of normal and
      vasectomized rats.

PMID- 4351202
TI  - Tissue explants used for enhancement of herpesvirus isolations.
AB  - Herpesvirus recovery from normal and experimentally infected simian tissues
      prepared into 10 to 20% homogenates was compared with that obtained by explanting
      these same tissues. The explant procedure was by far the more sensitive of the
      two methods. As a result, 8 herpesvirus isolations were obtained by conventional
      virus isolation procedures in contrast to 74 isolates when explants were made
      from these same tissue sources. There is also evidence to suggest that the
      explant method is more sensitive than the use of tissue homogenates for recovery
      of other viruses as well.

PMID- 4351203
TI  - Purification and properties of yeast histidinol phosphate phosphatase.

PMID- 4351204
TI  - Adenosine 3',5'-monophosphate and protein kinase dependent phosphorylation of
      ribosomal protein.

PMID- 4351205
TI  - Application of laser self-beat spectroscopic technique to the study of solutions
      of human plasma low-density lipoproteins.

PMID- 4351206
TI  - Electron paramagnetic resonance study of iodine-induced radicals of benzo( )
      pyrene and other polycyclic hydrocarbons.

PMID- 4351208
TI  - [Asteroid and filamentous intranuclear inclusions (electron microscopical
      studies)].

PMID- 4351207
TI  - Photochemical systems of Rhodospirillum rubrum. Light-induced reactions and
      biological functions of c-type cytochromes in relation to P-870.

PMID- 4351209
TI  - [Pituitary hormones].

PMID- 4351210
TI  - [Isolation of cyclic AMP using an alumina column and the improvement of its
      method: application of adenyl-cyclase assay].

PMID- 4351212
TI  - Dysfunction patterns analogous to frontal lobe system and caudate nucleus
      syndromes in some groups of minimal brain dysfunction.

PMID- 4351211
TI  - [Effectiveness of intermittent corticoid therapy in tuberculosis in children and
      adolescents].

PMID- 4351213
TI  - Is anatomy destiny? Panel: the changing role of women psychiatrists.

PMID- 4351214
TI  - New Jersey women physicians--their opinions on today's world.

PMID- 4351215
TI  - Clinical application of fluorescent staining of chromosomes.

PMID- 4351216
TI  - Purification and properties of a mutant bifunctional enzyme from the HisB gene of
      Salmonella typhimurium.

PMID- 4351217
TI  - Studies on the reconstitution of bovine erythrocyte superoxide dismutase. IV.
      Preparation and some properties of the enzyme in which Co(II) is substituted for
      Zn(II).

PMID- 4351218
TI  - Assembly of the mitochondrial membrane system. IX. Purification,
      characterization, and subunit structure of yeast and beef cytochrome oxidase.

PMID- 4351219
TI  - Assembly of the mitochondrial membrane system. X. Mitochondrial synthesis of
      three of the subunit proteins of yeast cytochrome oxidase.

PMID- 4351220
TI  - Binding of ( 3 H)concanavalin A to normal and transformed cells.

PMID- 4351221
TI  - Interactions of 3-aminopyridine adenine dinucleotide with dehydrogenases.

PMID- 4351222
TI  - Sialidase activity in transformed cells.

PMID- 4351223
TI  - Intraventricular septations complicating neonatal meningitis.

PMID- 4351224
TI  - Metastases of glioblastoma multiforme to cervical lymph nodes. Report of two
      cases.

PMID- 4351225
TI  - [Antitumor activities of sulfonates of methanesulfonic acid esters of eminoglycol
      on experimental tumors in mice and rats].

PMID- 4351227
TI  - [Studies on the autoxidation of carbohydrate and its derivatives. VII. Formation
      of the pigments in amino-carbonyl reaction of glucose].

PMID- 4351226
TI  - [Thin-layer chromatography on precoated adsorbents fixed with fused glass. V.
      Thin-layer chromatography on Kieselguhr sintered plate].

PMID- 4351228
TI  - [Plasma renin activity measurement by radioimmunoassay of angiotensin I. Critical
      study of the method and results as a function of sex and orthostatism].

PMID- 4351229
TI  - [Subacute form of herpetic meningoencephalitis. Apropos of 4 cases].

PMID- 4351231
TI  - [Statistical approach to the evaluation by various enzymatic characteristics of
      the potential pathogenicity of Staphylococcus].

PMID- 4351232
TI  - Gastrointestinal hormones.

PMID- 4351234
TI  - [Mammography in breast cancer].

PMID- 4351233
TI  - Metabolic aspects of alcohol and their biological significance.

PMID- 4351235
TI  - Enhanced release of dopamine  -hydroxylase and norepinephrine from sympathetic
      nerves by dibutyryl cyclic adenosine 3', 5'-monophosphate and theophylline.

PMID- 4351236
TI  - The specific binding of vitamin A acid to equine liver alcohol dehydrogenase.

PMID- 4351237
TI  - Mechanism of inactivation of rabbit muscle glyceraldehyde 3-phosphate
      dehydrogenase by ethacrynic acid.

PMID- 4351239
TI  - Xanthoma types in relation to the type of hyperlipoproteinemia.

PMID- 4351238
TI  - Increased binding of transfer ribonucleic acid species to ribosomes under
      conditions interfering with their aminoacylation.

PMID- 4351241
TI  - Early diagnosis of familial type II hyperlipoproteinemia.

PMID- 4351240
TI  - Acrokeratoelastoidosis mimicking palmo-plantar xanthomata.

PMID- 4351243
TI  - Atherosclerosis of heart valves and the formation of the corneal arcus as models
      for the study of atherosclerosis.

PMID- 4351242
TI  - Experiences with the homozygous cases of familial hypercholesterolemia. A report
      of 52 patients.

PMID- 4351244
TI  - The role of altered vascular permeability in the induction of experimental
      xanthomata.

PMID- 4351245
TI  - Advances in lipoprotein research. Biochemical and clinical aspects.

PMID- 4351246
TI  - [Serum alpha lipoprotein deficiency: study of a abnormal apo HDL].

PMID- 4351247
TI  - [Blood volume receptors and neuro-hormonal regulation of blood volume].

PMID- 4351248
TI  - [Cortical evoked potentials in optic nerve diseases].

PMID- 4351249
TI  - [Uptake and inactivation of ACTH in isolated fat cells].

PMID- 4351251
TI  - [Transplacental transmission of parainfluenza virus, type 3, in guinea pigs and
      mice].

PMID- 4351250
TI  - Endocrine profile of a specific prolactin inhibitor: Br-ergocryptine (CB 154). A
      preliminary report.

PMID- 4351252
TI  - [Hyperinsulinism: effect of a pancreatic insuloma and its extirpation on the
      blood coagulation system].

PMID- 4351253
TI  - [Metabolism during physical exertion].

PMID- 4351254
TI  - The problem-oriented medical synopsis. Applications to patient care, education,
      and research.

PMID- 4351255
TI  - The lysosome: a role in disease.

PMID- 4351256
TI  - Mechanisms of the crystal deposition diseases--gout and pseudogout.

PMID- 4351257
TI  - Hereditary sensory neuropathy, type II. Clinical, electrophysiologic, histologic,
      and biochemical studies of a Quebec kinship.

PMID- 4351258
TI  - Inositol dehydrogenase from the yeast Cryptococcus melibiosum.

PMID- 4351259
TI  - Evidence for the existence of lactate dehydrogenase X in embryonic chick liver.

PMID- 4351260
TI  - The ratio of type-I and -2 Cu(II) in human ceruloplasmin.

PMID- 4351261
TI  - Specificity and mode of action of acid carboxypeptidase from Aspergillus saitoi.

PMID- 4351263
TI  - Multiple thoracic nodules in a young asymptomatic woman.

PMID- 4351262
TI  - Inhibition of homogeneous angiotensin-converting enzyme of rabbit lung by
      synthetic venom peptides of Bothrops jararaca.

PMID- 4351264
TI  - Karyological analysis of Rous sarcoma virus-producing rat-kangaroo cell lines.

PMID- 4351265
TI  - [Unusual nuclear inclusions in lymphocytes and basal cells of the skin in lupus
      erythematosus].

PMID- 4351266
TI  - Sleep continuity changes in depression.

PMID- 4351267
TI  - Determination of anionic surfactants in water.

PMID- 4351268
TI  - Determination of particulate phosphorus by alkaline persulfate digestion.

PMID- 4351270
TI  - [Comparative research on silica metabolism in soft and calcified tissues in
      mammals].

PMID- 4351269
TI  - Analysis of chlorinated aromatic hydrocarbons by exhaustive chlorination:
      qualitative and structural aspects of the perchloro-derivatives of biphenyl,
      naphthalene, terphenyl, dibenzofuran, dibenzodioxin and DDE.

PMID- 4351271
TI  - [Electrophysiological study of the anterior olfactory bulb].

PMID- 4351272
TI  - [Antagonism between cyclic AMP and calcium on isolated depolarized aorta in the
      rat].

PMID- 4351273
TI  - [Fixation of tritiated female gonadal hormones in the hypothalamus of the rabbit:
      microelectrophysiological correlations].

PMID- 4351274
TI  - [Mechanism of masseter reflex inhibition started in the amygdaloid body and the
      lenticular loop. Mediator role of the trigeminal nerve spinal root nucleus].

PMID- 4351275
TI  - [Calorigenic effects of theophylline and cyclic dibutyryl-AMP in the rat adapted
      to different temperatures].

PMID- 4351276
TI  - [Circadian variations of the hypophyso-adrenal response to metopirone].

PMID- 4351277
TI  - [Characteristics of a locomotor type rhythm in the acute spinal cat].

PMID- 4351278
TI  - [Entrance as a function of the auditory system: physiological and ultrastructural
      correlations].

PMID- 4351279
TI  - [Effects of central gray matter lesions of the mesencephalon on switch-off and
      self stimulation responses in the hypothalamus].

PMID- 4351280
TI  - [Course of the occurrence of intranuclear inclusions of sympathic neurons after
      electric stimulation].

PMID- 4351281
TI  - [Fluctuations in excitability of precentral cortex interneurons in the monkey
      free of its movements during slow sleep and awakening].

PMID- 4351282
TI  - A rapid in vivo test for chromosomal damage.

PMID- 4351284
TI  - A note on the specific fixation, specific deactivation and non-specific
      inactivation of bacterial toxins by gangliosides.

PMID- 4351283
TI  - The mechanism of action of tetanus toxin: effect on synaptic processes and some
      particular features of toxin binding by the nervous tissue.

PMID- 4351285
TI  - Local tetanus in cats: the influence of neuromuscular activity on spinal
      distribution of  125 I labelled tetanus toxin.

PMID- 4351286
TI  - Vagal ascent and distribution of  125 I-tetanus toxin after injection into the
      anterior wall of the stomach.

PMID- 4351287
TI  - [Pulmonary neoplasms and adrenal gland insufficiency: study of a case and
      hypothesis on an ACTH-inhibiting factor (ACTH-IF) or an abnormal ACTH secreted by
      the tumor].

PMID- 4351288
TI  - [Insulinoma: report of 2 cases and classification of hypoglycemia].

PMID- 4351289
TI  - [Evolution of the afferent input into the cerebellum: its onto- and phylogenetic
      aspects].

PMID- 4351290
TI  - [Ontogenesis of the reflex activity of the spinal cord].

PMID- 4351291
TI  - [Histology of the suctorial disc of the sucking fish, Echeneis naucrates L. with
      remarks on the systematics of sustentacular tissue].

PMID- 4351292
TI  - [Electron microscopy and histochemical studies on the function of the branchial
      gland in cephalopods].

PMID- 4351293
TI  - Ultrastructural changes in the coronet cells of the saccus vasculosus from
      rainbow trout, Salmo gairdneri (Richardson), kept in sea water.

PMID- 4351295
TI  - Prejunctional depressant actions of strychnine on soleus neurotransmission in the
      cat.

PMID- 4351296
TI  - Sodium depletion and postcaval vein constriction on steroid secretion in the
      bullfrog.

PMID- 4351294
TI  - [The etiologic role of latent adenoviruses in fetal pathology and subsequent
      development of an infectious-allergic state in children with otorhinolaryngologic
      diseases].

PMID- 4351297
TI  - Energy metabolism of working muscle: concentration profiles of selected
      metabolites.

PMID- 4351298
TI  - Specific stimulation and inhibition of renal prostaglandin release by angiotensin
      analogs.

PMID- 4351299
TI  - Carcinoma of the sphenoid sinus.

PMID- 4351300
TI  - [Spinal and bulbar reflexes during sleep in man. Differences between the
      orbicularis oculi reflex, masseter reflex, and flexor reflex in REM sleep].

PMID- 4351301
TI  - Cyclic-3', 5'-AMP-dependent and independent protein kinase levels in normal and
      feline sarcoma virus transformed cells.

PMID- 4351302
TI  - Differences in macromolecular binding between cyclic AMP and its dibutyryl
      derivative in vitro.

PMID- 4351303
TI  - Effects of lipids on cyclic-nucleotide phosphodiesterases.

PMID- 4351304
TI  - A novel nucleolytic activity associated with rabbit liver tRNA
      nucleotidyltransferase.

PMID- 4351306
TI  - Storage cells of spleen and bone marrow in thalassemia: an ultrastructural study.

PMID- 4351305
TI  - In vitro activation of leukocyte glycogen synthetase.

PMID- 4351307
TI  - Recurrent Kaposi's varicelliform eruption in Darier's disease.

PMID- 4351308
TI  - Steroidogenesis and RNA synthesis in rat adrenal gland in vitro.

PMID- 4351310
TI  - Plasma growth hormone in the anesthetized rat. Effects of dibutyryl cyclic AMP,
      prostaglandin E 1 , adrenergic agents, vasopressin, chlorpromazine, amphetamine
      and L-dopa.

PMID- 4351309
TI  - Effect of LH on steroidogenesis and cyclic AMP accumulation in rat Leydig cell
      preparations and mouse tumor Leydig cells.

PMID- 4351312
TI  - Interaction of growth hormone and ACTH in the regulation of adrenocortical
      secretion in rats.

PMID- 4351311
TI  - Plasma LH changes following cortical spreading depression in female rats.

PMID- 4351313
TI  - The action of a human uterine protease on the estrogen receptor.

PMID- 4351314
TI  - Mechanism of action of gonadotropin. 3. Binding of adenosine 3',5'-monophosphate
      by the 105,000 X g supernatant fraction from homogenates of calf ovaries.

PMID- 4351315
TI  - TRF and thyroid hormones on prolactin secretion by rat anterior pituitary cells
      in vitro.

PMID- 4351317
TI  - Potentiation by angiotensin II of the vasopressin response to an increasing
      plasma osmolality.

PMID- 4351316
TI  - Stimulation of cyclic AMP accumulation in rat ovaries in vitro.

PMID- 4351318
TI  - Intranuclear receptor for androgens in rat epididymis.

PMID- 4351319
TI  - Minimal O 2  consumption as an index of thyroid status: standardization of
      method.

PMID- 4351320
TI  - Progesterone and corticosterone binding in rabbit uterine cytosols.

PMID- 4351321
TI  - [Effect of lipolytic hormones on release of FFA from adipose tissue of
      thyroidectomized rats and treated with thyroxine in vitro].

PMID- 4351322
TI  - [Paget's carcinoma].

PMID- 4351323
TI  - Goat-pox: an anthropozoonosis.

PMID- 4351324
TI  - Evoked cortical potentials in experimental spinal cord trauma.

PMID- 4351327
TI  - Subacute cerebellar degeneration and Eaton-Lambert syndrome with bronchogenic
      carcinoma. A case report.

PMID- 4351329
TI  - A pleomorphic adenoma (so-called mixed tumor) in the wall of a dentigerous cyst.

PMID- 4351328
TI  - Rod (nemaline) bodies in the skeletal muscle of an acute schizophrenic patient.

PMID- 4351330
TI  - [Tracheo-bronchography: rare complication of angiography].

PMID- 4351331
TI  - Considerations on the correlation between the blood groups and the incidence of
      cerebral tumours.

PMID- 4351332
TI  - [Use of cytochrome "C" in treating acute massive hemorrhage].

PMID- 4351341
TI  - A study of the relationship of reticuloendotheliosis virus to the avian leukosis
      sarcoma complex of viruses.

PMID- 4351342
TI  - A temperature-sensitive mutant of Rous sarcoma virus that is defective for
      replication.

PMID- 4351343
TI  - Studies on the mechanism of neuromuscular transmission in insects. The effect of
      glutamic acid.

PMID- 4351344
TI  - Two different activities of alkaline phosphatase in cultured mammalian cells.

PMID- 4351345
TI  - The purification of pig vitamin D-induced intestinal calcium binding protein.

PMID- 4351346
TI  - Studies on phosphodiesterase from oxyntic cells of bullfrog gastric mucosa. I.
      Intracellular localization, partial purification, and properties.

PMID- 4351347
TI  - Vitamin D 3 -25-hydroxylase: tissue occurrence and apparent lack of regulation.

PMID- 4351348
TI  - Covalent attachment of fluorescent groups to the 5'-end of transfer RNA.

PMID- 4351349
TI  - A rate-zonal centrifugation procedure for screening particle populations by
      sequential product recovery utilizing edge-unloading zonal rotors.

PMID- 4351350
TI  - Effect of osmolality and phosphate, 'tris', 'tes', 'mes', and 'hepes' hydrogen
      ion buffers on the motility of bull spermatozoa stored at 37 or 5 degreesC.

PMID- 4351351
TI  - A polymeric form of haemoglobin-binding protein in sheep following metabolic and
      hormonal disturbance.

PMID- 4351352
TI  - Sudden and unexpected deaths in infants: histology and virology.
AB  - The histological appearance of lungs of children whose death had been sudden and
      unexpected has been studied in relation with the viruses found at necropsy. Fifty
      one children were investigated and in 33 the lungs had the histological
      appearance widely accepted as characteristic of the condition previously termed
      "cot death." Sixteen had the histological appearance of lymphocytic
      bronchiolitis, and it was from this group only that viruses were isolated. The
      viruses isolated were those associated with respiratory infections. Two patients
      showed the histological appearance of bacterial bronchopneumonia. Viruses are
      probably responsible for a substantial proportion of unexpected sudden deaths in
      infancy.

PMID- 4351353
TI  - Actinomycin D for Wilm's tumour.

PMID- 4351354
TI  - Antibiotic sensitivity of Clostridium perfringens and L-forms of C. perfringens
      induced by bacteriocin.

PMID- 4351355
TI  - Radioimmunoassay. Practices and pitfalls.

PMID- 4351356
TI  - Use of angiotensin II antagonists in experimental hypertension.

PMID- 4351357
TI  - Effects of a specific competitive antagonist of angiotensin II on arterial
      pressure and adrenal steroid secretion in dogs.

PMID- 4351358
TI  - Importance of potassium in the regulation of aldosterone production.

PMID- 4351359
TI  - Physiological receptors as physicochemical entities.

PMID- 4351360
TI  - A model of the human circulation. Regulation by autonomic nervous system and
      renin-angiotensin system, and influence of blood volume on cardiac output and
      blood pressure.

PMID- 4351361
TI  - Simultaneous competitive protein binding assay for cortissol, cortisone, and
      prednisolone in plasma, and its clinical application.

PMID- 4351362
TI  - Kinetic colorimetric measurement of serum lactate dehydrogenase activity.

PMID- 4351363
TI  - Hippocampal epilepsy produced by ouabain. Studies of cerebral circulation and
      ionic metabolism.

PMID- 4351364
TI  - Relationship of epithelial membrane potentials to corneal potential.

PMID- 4351365
TI  - Ion pumps in the cornea and their stimulation by epinephrine and cyclic-AMP.

PMID- 4351366
TI  - [The use of thin-layer chromatography for the quantitative evaluation and
      determination of the purity of medicinal agents].

PMID- 4351367
TI  - Regulation of electrolyte balance in marine birds with special reference to the
      role of the pituitary-adrenal axis in the duck (Anas platyrhynchos).

PMID- 4351369
TI  - Prolactin and osmoregulation in fishes.

PMID- 4351368
TI  - Lungfishes and amphibians: endocrine adaptation and the transition from aquatic
      to terrestrial life.

PMID- 4351370
TI  - Herpesviruses and cancer: introduction.

PMID- 4351371
TI  - Herpesvirus and the frog renal adenocarcinoma.

PMID- 4351372
TI  - Role of herpesviruses in malignant lymphoma in rabbits.

PMID- 4351373
TI  - Herpesviruses saimiri and ateles--their role in malignant lymphomas of monkeys.

PMID- 4351375
TI  - In vitro cell transformation by herpesviruses.

PMID- 4351374
TI  - Possible role of Herpesvirus hominis, type 2, in human cervical cancer.

PMID- 4351376
TI  - Biochemical transformation of L-cells with ultraviolet-irradiated herpes simplex
      virus.

PMID- 4351377
TI  - Role of Epstein-Barr virus in infectious mononucleosis and malignant lymphomas in
      man.

PMID- 4351378
TI  - Electron spin resonance studies on aqueous methylene blue solutions.

PMID- 4351379
TI  - [Viral hepatitis].

PMID- 4351380
TI  - Maori art and pseudo-hypoparathyroidism--a medical contribution to prehistoric
      anthropology.

PMID- 4351382
TI  - Bone case of the month.

PMID- 4351381
TI  - Treatment of oral syndrome obesity with non-traditional appetite control plan.

PMID- 4351383
TI  - Day care: Pandora's box?

PMID- 4351384
TI  - Role of cyclic adenosine 3',5'-monophosphate in the in vivo expression of the
      galactose operon of Escherichia coli.
AB  - Studies of levels of galactokinase in Escherichia coli with mutations affecting
      synthesis of, or response to, cyclic adenosine 3',5'-monophosphate show that this
      nucleotide does not play a major role in expression of the galactose operon,
      causing at most a twofold stimulation. The discrepancy between our in vivo
      results and the marked stimulation by cyclic adenosine 3',5'-monophosphate in in
      vitro systems indicates that current cell-free systems lack a factor which allows
      efficient expression of the galactose operon even in the absence of cyclic
      adenosine 3',5'-monophosphate or of the binding protein for this nucleotide.

PMID- 4351385
TI  - Genetic mutations affecting the respiratory electron-transport system of the
      photosynthetic bacterium Rhodopseudomonas capsulata.
AB  - Alternative energy-converting systems permit the nonsulfur purple photosynthetic
      bacterium Rhodopseudomonas capsulata to grow either with light or (dark)
      respiration as the source of energy. Respiratory mutants, unable to grow
      aerobically in darkness, can be readily isolated and the defective step(s) in
      their respiratory mechanisms can be identified by study of biochemical activities
      in membrane fragments derived from photosynthetically grown cells. Such analysis
      of appropriate mutants and revertants permits construction of a model for the
      respiratory electron-transport system of the wild type. The results obtained
      indicate differential channeling of electrons derived from succinate and reduced
      nicotinamide adenine dinucleotide, and are interpreted in terms of a branched
      electron-transport scheme. The scheme provides a guide for further, more refined
      analysis of the respiratory mechanisms through biochemical genetic approaches,
      and several of the mutants isolated can be exploited for investigation of
      unsolved problems relating to interactions between respiratory and photosynthetic
      electron transport and the mechanism of inhibition of bacteriochlorophyll
      synthesis by molecular oxygen.

PMID- 4351386
TI  - Cyclic adenosine 3',5'-monophosphate in Escherichia coli.
AB  - The concentration of cyclic adenosine 3',5'-monophosphate (c-AMP) in Escherichia
      coli growing on different sources of carbon was studied. Cultures utilizing a
      source of carbon that supported growth relatively poorly had consistently higher
      concentrations of c-AMP than did cultures utilizing sugars that supported rapid
      growth. This relationship was also observed in strains defective in c-AMP
      phosphodiesterase and simultaneously resistant to catabolite repression; in such
      strains the c-AMP concentration was slightly higher for several sources of carbon
      tested. Cultures continued to synthesize c-AMP and secreted it into the medium,
      under conditions that brought about an inhibition of the intracellular
      accumulation of the cyclic nucleotide. Transient repression of the synthesis of
      beta-galactosidase was not associated with an abrupt decrease in the cellular
      concentration of c-AMP.

PMID- 4351388
TI  - Isolation and characterization of plasmid deoxyribonucleic acid from
      Streptococcus mutans.
AB  - A small plasmid with a molecular weight of approximately 3.0 x 10(6) and present
      to the extent of about 16 copies per chromosomal genome equivalent was isolated
      from Streptococcus mutans strain LM-7.

PMID- 4351387
TI  - Glucose fermentation products in Ruminococcus albus grown in continuous culture
      with Vibrio succinogenes: changes caused by interspecies transfer of H 2 .
AB  - The influence of a H(2)-utilizing organism, Vibrio succinogenes, on the
      fermentation of limiting amounts of glucose by a carbohydrate-fermenting, H(2)
      producing organism, Ruminococcus albus, was studied in continuous cultures.
      Growth of V. succinogenes depended on the production of H(2) from glucose by R.
      albus. V. succinogenes used the H(2) produced by R. albus to obtain energy for
      growth by reducing fumarate in the medium. Fumarate was not metabolized by R.
      albus alone. The only products detected in continuous cultures of R. albus alone
      were acetate, ethanol, and H(2). CO(2) was not measured. The only products
      detected in the mixed cultures were acetate and succinate. No free H(2) was
      produced. No formate or any other volatile fatty acid, no succinate or other
      dicarboxylic acids, lactate, alcohols other than ethanol, pyruvate, or other keto
      acids, acetoin, or diacetyl were detected in cultures of R. albus alone or in
      mixed cultures. The moles of product per 100 mol of glucose fermented were
      approximately 69 for ethanol, 74 for acetate, 237 for H(2) for R. albus alone and
      147 for acetate and 384 for succinate for the mixed culture. Each mole of
      succinate is equivalent to the production of 1 mol of H(2) by R. albus. Thus, in
      the mixed cultures, ethanol production by R. albus is eliminated with a
      corresponding increase in acetate and H(2) formation. The mixed-culture pattern
      is consistent with the hypothesis that nicotinamide adenine dinucleotide (reduced
      form), formed during glycolysis by R. albus, is reoxidized during ethanol
      formation when R. albus is grown alone and is reoxidized by conversion to
      nicotinamide adenine dinucleotide and H(2) when R. albus is grown with V.
      succinogenes. The ecological significance of this interspecies transfer of H(2)
      gas and the theoretical basis for its causing changes in fermentation patterns of
      R. albus are discussed.

PMID- 4351389
TI  - Purinergic autonomic neurones.

PMID- 4351390
TI  - Enzymes in bovine milk: a review.

PMID- 4351391
TI  - Comparative study of two RD 114 virus-indicator cell lines, KC and KB.

PMID- 4351393
TI  - Lifespan and incidence of cancer and other diseases in selected long-lived inbred
      mice and their F 1  hybrids.

PMID- 4351392
TI  - Patterns of antibodies to Epstein-Barr virus-induced early antigens in Burkitt's
      lymphoma. Comparison of dying patients with long-term survivors.

PMID- 4351394
TI  - Spontaneous tumors in C3H-A vy  and C3H-A vy fB mice: high incidence in the
      United States and low incidence in Australia.

PMID- 4351395
TI  - Lysis of tumor cells by antibody and complement. 1. Lack of correlation between
      antigen content and lytic susceptibility.

PMID- 4351396
TI  - Thymic dependency of tumor-induced immunodepression.

PMID- 4351397
TI  - Induction of lymphocytic leukemia, lymphosarcoma, reticulum cell sarcoma, and
      osteogenic sarcoma in the Syrian golden hamster by oncogenic DNA simian virus 40.

PMID- 4351399
TI  - Adjuvants for a tumor-specific vaccine: Bordetella pertussis or mycobacterial
      cell walls attached to oil droplets.

PMID- 4351398
TI  - Carcinoembryonic antigen in normal human saliva.

PMID- 4351400
TI  - Immunosuppression and experimental lymphoma.

PMID- 4351401
TI  - 4-Methanesulfonyloxybutanol: hydrolysis of busulfan.

PMID- 4351402
TI  - Electrophysiologic effects of diphenidol in isolated cardiac tissue.

PMID- 4351403
TI  - Blockade of adrenergic potentiating effect of angiotensin by 1-Sar-8-Ala
      angiotensin II.

PMID- 4351405
TI  - [Knowledge of drugs. 3. Drugs acting on the peripheral nerves].

PMID- 4351404
TI  - Pharmacology of cyanate. II. Effects on the endocrine system.

PMID- 4351406
TI  - Heredity and cancer in man.

PMID- 4351407
TI  - The familial dyslipoproteinemias.

PMID- 4351408
TI  - [Primary multiple cancer of the large intestine and other organs].

PMID- 4351409
TI  - [Cancer of the large intestine].

PMID- 4351410
TI  - The funding crisis: an opportunity for growth.

PMID- 4351411
TI  - The background and promise of tumor virology, immunology, and chemotherapy and a
      challenge to radiotherapy. Janeway Memorial lecture.

PMID- 4351412
TI  - Reliability of skeletal age assessments.

PMID- 4351413
TI  - The enlarge foramen ovale.

PMID- 4351415
TI  - Simple vulvectomy--a 10-year review.

PMID- 4351414
TI  - Immune response in families of children with acute lymphoblastic leukaemia.

PMID- 4351417
TI  - Adenovirus infection and disease. I. Some characteristics of an isolate from
      chickens in Indiana.

PMID- 4351416
TI  - Studies on differentiation of avian pox viruses.

PMID- 4351418
TI  - Adenovirus infection and disease. II. Histopathology of natural and experimental
      disease.

PMID- 4351419
TI  - Characterization of two reoviruses isolated from turkeys with infectious
      enteritis.

PMID- 4351420
TI  - Isolation and characterization of a virus associated with arthritis of chickens.

PMID- 4351421
TI  - Isolation and characterization of viruses associated with transmissible enteritis
      (bluecomb) of turkeys.

PMID- 4351422
TI  - The role of dermal blood vessels in the pathogenesis of malignant atrophic
      papulosis (Degos' disease). A study of two cases using enzyme histochemical,
      fibrinolytic, electron-microscopical and immunological techniques.

PMID- 4351423
TI  - Effect of ADP-induced aggregation on  32 PO 4  incorporation into phosphatidic
      acid and the phosphoinositides of rabbit platelets.

PMID- 4351424
TI  - [Adult Kala-azar observed on the Ivory Coast].

PMID- 4351425
TI  - Human growth hormone: a comparison of the results of plasma and serum assays
      using double-antibody techniques.

PMID- 4351426
TI  - A procedure for the determination of a renin inhibitor in human plasma.

PMID- 4351427
TI  - Effect of ampicillin on the urinary output of steroidal hormones in pregnant and
      non-pregnant women.

PMID- 4351428
TI  - Purine metabolism in primitive erythrocytes.

PMID- 4351429
TI  - Biochemical studies in the vole, Microtus montanus. I. The daily variation of
      hepatic glucose-6-phosphatase and liver glycogen.

PMID- 4351430
TI  - Biochemical studies in the vole, Microtus montanus. II. The effects of a
      Trypanosoma brucei gambiense infection on the diurnal variation of hepatic
      glucose-6-phosphatase and liver glycogen.

PMID- 4351431
TI  - Hydrolytic enzymes of the hepatopancreas of the ascidian, Pyura stolonifera.

PMID- 4351432
TI  - Wax ester biosynthesis by isolated membrane fractions from calanoid copepods.

PMID- 4351433
TI  - Enzymes in facultative anaerobiosis of molluscs. I. Malic enzyme of oyster
      adductor muscle.

PMID- 4351434
TI  - [D-altronate: NAD-oxidoreductase from Escherichia coli K12. Kinetic studies].

PMID- 4351436
TI  - Arginyl-transfer ribonucleic-acid synthetase from Bacillus stearothermophilus.
      Purification, properties and mechanism of action.

PMID- 4351435
TI  - [D-mannonate: NAD-oxidoreductase from Escherichia coli K12. Kinetic studies of
      the enzymatic mechanism].

PMID- 4351437
TI  - Energy-dependent changes in membranes of Rhodospirillum rubrum chromatophores as
      measured by 8-anilino-naphthalene-1-sulfonic acid.

PMID- 4351438
TI  - Structure of the parasporal inclusion of Bacillus thuringiensis Berliner:
      characterization of a repetitive subunit.

PMID- 4351440
TI  - The subunit structure of the pyruvate-dehydrogenase complex from Escherichia coli
      K-12. The core complex.

PMID- 4351439
TI  - Studies on the interaction of ligands with phosphorylase b using a spin-label
      probe.

PMID- 4351441
TI  - Benzene metabolism of Moraxella species.

PMID- 4351442
TI  - Characterization of the native and denatured conformations of tRNA Ser and tRNA
      Phe from yeast.

PMID- 4351443
TI  - Effect of strychnine on the primary evoked response and on the corticofugal
      reflex discharge.

PMID- 4351444
TI  - Reflexes involving triceps surae from the ankle joint of the cat.

PMID- 4351445
TI  - Peripheral neuropathies in diseases of internal organs.

PMID- 4351446
TI  - The development of the chick tertiary bronchus. I. General development and the
      mode of production of the osmiophilic inclusion body.

PMID- 4351448
TI  - Increased metabolic clearance of cortisol by stress-susceptible swine.

PMID- 4351447
TI  - The development of the chick tertiary bronchus. II. The origin of the surface
      lining system.

PMID- 4351449
TI  - Corneal immune response to Herpes simplex virus antigens.

PMID- 4351450
TI  - Prevention of MIF activity by agents known to increase cellular cyclic AMP.

PMID- 4351451
TI  - The effects of tetanus toxin on the motor end-plates of the mouse. An electron
      microscopic study.

PMID- 4351452
TI  - [Ultrastructural aspects and biochemical significance of metachromatic
      granulations and other inclusions in cultured fibroblasts from lipidosis and
      mucopolysaccharidosis].

PMID- 4351453
TI  - Follow-up after hydatidiform mole: studies using radioimmunoassay for urinary
      human chorionic gonadotrophin (HCG).

PMID- 4351454
TI  - Fusion of erythrocytes by Sendai virus studied by immuno-freeze-etching.
AB  - Extensive fusion of human erythrocytes agglutinated by Sendai virus was observed
      after 30 s of incubation at 37 C. Electron microscopy of thin sections failed to
      reveal the presence of virions, viral fragments, or discrete viral antigens
      reactive with ferritin-labeled antibody at the sites of fusion. Immuno
      freezeetching of membrane surfaces demonstrated the dispersal of viral envelope
      antigens from what appeared to be original sites of viral attachment. Virus
      induced clustering of membrane glycoproteins was interpreted as resulting from
      interaction of viral antigens with membrane receptor proteins and forming the
      structural basis for fusion of membranes with one another.

PMID- 4351455
TI  - Lack of sequence homology between the 70S RNA of various RNA tumor viruses and
      the DNA of simian virus 40 or polyoma virus.
AB  - No significant hybridization was detected of DNA from simian virus 40 or polyoma
      virus, and of 70S RNA from avian myeloblastosis virus, murine leukemia virus
      (Rauscher), murine sarcoma virus (Kirsten), RD-114B, simian sarcoma virus-1, or
      Mason-Pfizer virus.

PMID- 4351456
TI  - Virus-induced proteins in pseudorabies-infected cells. I. Acid-extractable
      proteins of the nucleus.
AB  - Three basic proteins have been identified in chromatin preparations from
      pseudorabies virus-infected cells. They appear to be virus specified and are
      similar in size and charge to host histones; one difference however is that they
      contain tryptophan. All are produced by 3 h postinfection, and two (IP II and
      III) seem to be arginine rich. Three similar proteins are also found in herpes
      simplex MP 17-infected cells, and two of these co-electrophorese with two of the
      pseudorabies proteins. Partially purified preparations of pseudorabies virus
      contain low amounts of all three proteins.

PMID- 4351457
TI  - Polioviruses, coxsackieviruses, and echoviruses comparison of the genomes by RNA
      hybridization.
AB  - Hybridization of single-stranded RNA from virions of human enteroviruses with
      denatured double-stranded RNA from infected cells indicates that a minimum of
      about 5% of the genome is shared by these viruses. Polynucleotide sequence
      relationships, furthermore, are consistent with the biologic classification into
      polioviruses, coxsackieviruses groups A and B, and echoviruses. In general, about
      30 to 50% of the nucleotide sequences are shared by different serotypes of virus
      within each of these major groups, whereas among different groups less than 20%
      homology is observed. Coxsackievirus B4 appears to be more closely related to
      echoviruses than to group A coxsackieviruses, whereas polioviruses are only
      distantly related to any of the other agents.

PMID- 4351458
TI  - RNA synthesis in cells infected with herpes simplex virus. VII. Control of
      transcription and of transcript abundancies of unique and common sequences of
      herpes simplex virus 1 and 2.
AB  - Analysis of the kinetics of hybridization in liquid of labeled herpes simplex
      virus (HSV) 1 and 2 DNAs with excess unlabeled RNA extracted at 2 (early) and 8
      (late) h postinfection revealed the following. (i) The RNA transcripts present in
      the HSV-1-infected cells at 2 and 8 h postinfection are complementary to 44 and
      48% of HSV-1 DNA. The RNA transcripts present in the HSV-2-infected cells at 2
      and 8 h postinfection are complementary to 21 and 50% of HSV-2 DNA. (ii) The
      transcripts present in 2-h HSV-1- or HSV-2-infected cells treated with
      cycloheximide are complementary to 44 and 45% of the respective DNAs. (iii) The
      RNA transcripts present in the HSV-1-infected cells at 2 h postinfection and in
      HSV-2-infected cells at 8 h postinfection form 2 classes, abundant and scarce,
      differing in molar concentrations. The RNA transcripts present in the HSV-2
      infected cells at 2 h postinfection form only one abundance class. (iv) The
      transcripts present in the HSV-1-infected cells at 8 h postinfection are
      complementary to 24% of HSV-2 DNA and therefore 50% of the transcribed HSV-1
      sequences are shared by the two viruses. Of the RNA sequences complementary to
      HSV-2 DNA, 13% arise from HSV-1 templates specifying abundant RNA and 11% arise
      from HSV-1 templates specifying scarce RNA. Thus, the DNA sequences shared in
      common by HSV-1 and HSV-2 DNAs constitute 71% of the HSV-1 templates specifying
      abundant RNA and 39% of sequences specifying scarce RNA.

PMID- 4351459
TI  - Radioimmunoassay for avian C-type virus group-specific antigen: detection in
      normal and virus-transformed cells.
AB  - A radioimmunoassay has been developed for detection of avian C-type virus (30,000
      mol wt) group-specific (gs) antigen. The method is 10- to 1,000-fold more
      sensitive than immunological methods previously available. By the
      radioimmunoassay technique, normal chicken embryo cells, which have previously
      been classified as gs negative or weakly gs positive, contain clearly detectable
      amounts of gs antigen. The assay has been used to study the effect of chemical
      induction and superinfection by mammalian C-type viruses on the expression of
      avian gs antigen in mammalian cells nonproductively transformed by avian sarcoma
      viruses.

PMID- 4351460
TI  - Complementary RNA species isolated from vesicular stomatitis (HR strain)
      defective virions.
AB  - The wild-type strain of vesicular stomatitis virus (VSV) contains in its complete
      virion (VSV-1, B particles) a minus strand RNA. The principle defective particle
      of the wild-type strain (VSV-111, T particles) contains a shorter minus strand,
      homologous to part of the VSV-1 genome. Neither virion contains any detectable
      complementary (plus) strand RNA. In contrast, a preparation of a heat-resistant
      (HR) strain of VSV containing defective virions was found to contain both plus
      (21%) and minus strand RNA, present in several distinct size classes. It was
      found that the RNA in the HR virion preparation was at least 94% single-stranded
      and principally (96%) in ribonucleoprotein complexes. On extraction the plus and
      minus strand RNA species partially annealed to give a population of double- and
      multistranded RNA species. A small amount of RNA polymerase activity was
      associated with the HR defective virus preparation.

PMID- 4351462
TI  - Electrophoretic differences in the capsid proteins of simian virus 40 plaque
      mutants.
AB  - The structural proteins of three mutants of simian virus 40 (SV40) which differ
      in plaque size, temperature sensitivity, oncogenicity, host cell restriction, and
      immunological properties were studied. The polypeptide components of these SV40
      strains could not be distinguished by their polyacrylamide gel electrophoretic
      patterns. When the dissociated virions of two of the mutants were analyzed by the
      isoelectric focusing technique in a urea gradient, the capsid protein peaks were
      found to differ significantly in their isoelectric points. The capsid protein of
      the small-plaque mutant had an isoelectric point of pH 6.51 as compared with pH
      6.28 for the large-plaque strain. Isoelectric focusing of the isolated capsid
      protein revealed three components, a single major subunit and two minor forms.
      The coat proteins of two of the mutants, small-plaque and minute-plaque strains,
      were indistinguishable by this technique. The capsid protein peaks obtained by
      isoelectric focusing were further analyzed by polyacryalmide gel electrophoresis.

PMID- 4351461
TI  - Suppression of amber mutations of bacteriophage T4 gene 43 (DNA polymerase) by
      translational ambiguity.
AB  - The growth properties of twelve different amber (am) mutants of bacteriophage T4
      gene 43 (DNA polymerase) were examined by using nonpermissive (su(-)) as well as
      permissive (su(+)) Escherichia coli hosts. It was found that most of these
      mutants were measurably suppressed in su(-) hosts by translational ambiguity
      (misreading of codons during protein synthesis). The ability of these mutants to
      grow in response to this form of weak suppression probably means that the T4 gene
      43 DNA polymerase can be effective in supporting productive DNA replication when
      it is supplied in small amounts. By similar criteria, studies with other phage
      mutants suggested that the products of T4 genes 62 (uncharacterized), 44
      (uncharacterized), 42 (dCMP-hydroxymethylase), and 56 (dCTPase) are also
      effective in small amounts. Some T4 gene products, such as the product of gene 41
      (uncharacterized), seem to be partially dispensable for phage growth since am
      mutants of such genes do propagate, although weakly, in streptomycin-resistant
      su(-) hosts which appear to have lost the capacity to suppress am mutations by
      ambiguity.

PMID- 4351463
TI  - Cytomegalovirus replication in cells pretreated with 5-iodo-2'-deoxyuridine.
AB  - The replication of human cytomegalovirus (CMV) in cells pretreated with 5-iodo-2'
      deoxyuridine (IUdR) was studied. Pretreatment of cells with IUdR enhanced several
      parameters of virus replication. Virus grown in drug-treated cells exhibited a
      shorter eclipse period and the cells produced more infectious virus sooner than
      did untreated cells. There was an approximate fivefold increase in virus yield
      per cell in the drug-treated samples when compared to control cultures. The time
      required for plaque development was shortened by 6 days in drug-treated cultures.
      Pretreatment of cells with IUdR also increased plaquing efficiency of the virus
      by approximately 10-fold. The enhancement of virus replication by IUdR was
      further demonstrated by varying the multiplicity of infection. In a 7-day period
      there was a 100-fold increase in sensitivity of the cultures for virus detection
      when the cells had been previously exposed to IUdR. The data presented indicate
      the possibility that IUdR interferes with the production of a cellular product
      inhibitory for CMV replication.

PMID- 4351464
TI  - Growth characteristics of cytomegalovirus in human fibroblasts with demonstration
      of protein synthesis early in viral replication.
AB  - In high-multiplicity infection of human fibroblasts, human cytomegalovirus of WI
      38 human diploid cells produced early cell rounding 6 to 24 h after inoculation.
      This early cell rounding was caused only by inoculation with infectious virions.
      Inhibitors of protein synthesis, but not DNA inhibitors, prevented this
      cytopathic effect. Apparently, a new protein is synthesized in infected
      fibroblasts from about 2 h postinoculation. Infectivity of cell-associated and
      supernatant infectious virus reached maximal levels at 5 to 7 and 10 days
      postinoculation, respectively. Synthesis of DNA, infectious virus, complement
      fixing antigen, and precipitin antigen all began between 24 and 48 h, with the
      bulk of synthesis occurring 48 to 96 h postinoculation.

PMID- 4351466
TI  - Intrauterine infection with herpes simplex virus. Resultant congenital
      malformations.

PMID- 4351465
TI  - Nonproductive infection of guinea pig cells with human cytomegalovirus.
AB  - Human cytomegalovirus was capable of adsorbing to and penetrating guinea pig
      cells, but was unable to replicate new virus. Cultures infected with virus
      inoculum of high titer showed a cytopathic effect (CPE) characterized by cell
      rounding. This CPE depended upon the presence of infectious virus, and its extent
      was directly related to the multiplicity of infection. Staining by indirect
      immunofluorescence by using human convalescent sera was positive as early as 4 h
      postinfection. Maximal fluorescence was observed 24 h postinfection when 50% of
      the cells contained fluorescent antigens both in nuclei and cytoplasm. No
      evidence for viral replication was found, and no defective particles were
      detected by electron microscopy. Treatment with actinomycin D or with
      cycloheximide strongly inhibited both the fluorescent antigens and the CPE,
      whereas 5-fluorodeoxyuridine and bromodeoxyuridine were ineffective.

PMID- 4351467
TI  - Benign intrathoracic lesions mimicking recurrent cancer.

PMID- 4351468
TI  - Hematologic and serum electrolyte values of the C57BL-6J male mouse in maturity
      and senescence.

PMID- 4351470
TI  - Breeding the African green monkey, Cercopithecus aethiops, in a laboratory
      environment.

PMID- 4351469
TI  - Methodology and management of simian toxicology studies with emphasis on special
      technics.

PMID- 4351471
TI  - Pathogenic properties of Molineus torulosus in capuchin monkeys, Cebus apella.

PMID- 4351473
TI  - Response of mice to Corynebacterium kutscheri on footpad injection.

PMID- 4351472
TI  - Cataract development in streptozotocin-diabetic monkeys (Macaca nemestrina).

PMID- 4351475
TI  - Some observations on the circadian rhythm of Choloepus hoffmanni, the two-toed
      sloth.

PMID- 4351474
TI  - Comparison of old tuberculin and purified protein derivative in Macaca mulatta.

PMID- 4351476
TI  - Amino acid levels in the plasma of fasting macaques (Macaca cyclopis, M.
      fascicularis, and M. mulatta).

PMID- 4351477
TI  - Isolation and in vitro characterization of a herpesvirus from field mouse
      (Microtus pennsylvanicus).

PMID- 4351478
TI  - Production of hyperimmune serum with mature rabbits.

PMID- 4351480
TI  - Fibrosarcoma associated with Cysticercus fasciolaris.

PMID- 4351479
TI  - Effect of anesthetic agents on exercised, atropinized rats.

PMID- 4351481
TI  - Some characteristics of strain SJL-JDg mice.

PMID- 4351482
TI  - Differential diagnosis of an obscure bone disease in an infant rhesus monkey.

PMID- 4351484
TI  - Meckel's diverticulum in a rat.

PMID- 4351483
TI  - A method for preventing oral ingestion of topically applied materials.

PMID- 4351485
TI  - A mouse bleeding technic yielding consistent volume with minimal hemolysis.

PMID- 4351486
TI  - Basal-cell tumor in a Virginia opossum (Didelphis marsupialis).

PMID- 4351487
TI  - Spontaneous lesions seen at necropsy in 7 owl monkeys (Aotus trivirgatus).

PMID- 4351488
TI  - Solomon A. Berson and Rosalyn S. Yalow: a scientific appreciation.

PMID- 4351489
TI  - Radioimmunoassay of human plasma ACTH and the pathogenesis of Cushing's disease.

PMID- 4351490
TI  - The assay of ACTH in plasma.

PMID- 4351491
TI  - Observations on the control and release of growth hormone in plasma.

PMID- 4351492
TI  - Berson and Yalow's radioimmunoassay for parathyroid hormone (PTH): a clinical
      progress report.

PMID- 4351493
TI  - Secondary hyperparathyroidism.

PMID- 4351494
TI  - Possible clues in the continuing search for the subcellular basis of thyroid
      hormone action.

PMID- 4351495
TI  - Nonsegregated acute psychiatric admissions to general hospitals--continuity of
      care within the community hospital.

PMID- 4351496
TI  - Proteins of human cortical neurons during development.

PMID- 4351497
TI  - The effects of arterial blood pressure on the regional cerebral blood volume by X
      ray fluorescence.

PMID- 4351498
TI  - [Central nervous system and the secretion of ACTH (a review of the literature)].

PMID- 4351499
TI  - [Age and sex distribution in urolithiasis with special reference to the nature of
      calculi].

PMID- 4351500
TI  - Concentrations of human chorionic gonadotropin, progesterone, and unconjugated
      and total estriol in umbilical artery and vein plasma at term.

PMID- 4351502
TI  - Fibrous histiocytoma of the paranasal sinuses. Report of a case.

PMID- 4351501
TI  - The influence of oral contraceptive steroids on serum lipids.

PMID- 4351503
TI  - Synovial sarcoma of the head and neck.

PMID- 4351504
TI  - Bilateral glomus tumors of the temporal bone. Report of a case.

PMID- 4351505
TI  - Lipid composition of selected strains of Yersinia pestis and Yersinia
      pseudotuberculosis.

PMID- 4351506
TI  - The enzymic synthesis of disialoganglioside: rat brain cytidine-5'-monophospho-N
      acetylneuraminic acid: monosialoganglioside (G M1 ) sialyltransferase.

PMID- 4351507
TI  - Lipids in tissues of the eye. 8. Sphingomyelinase of the lens.

PMID- 4351508
TI  - Gonadotropin receptor of a mouse luteoma: interactions with luteinizing hormone
      (LH) and its   and   subunits.

PMID- 4351509
TI  - The stimulation of bovine epididymal sperm metabolism by cyclic nucleotide
      phosphodiesterase inhibitors.

PMID- 4351510
TI  - The effects of cyclic nucleotide phosphodiesterase inhibitors on ejaculated
      porcine spermatozoan metabolism.

PMID- 4351511
TI  - Cell-mediated immunity and antibodies to Herpesvirus hominis type 1 in oral
      leukoplakia and carcinoma.
AB  - Cell-mediated and humoral immune responses to Herpesvirus hominis type 1 (HVH1)
      and Candida albicans were studied in patients with leukoplakia, showing a
      histological spectrum of changes from epithelial keratosis to acanthosis and
      atypia, and in patients with carcinoma. The results were ranked according to
      increasing values of stimulation indices of lymphocyte transformation to HVH1,
      and the corresponding macrophage migration inhibition indices, and complement
      fixing antibody titres of each patient were correlated. This revealed that most
      patients with epithelial atypia were clustered to that end of the spectrum which
      had the highest stimulation and migration indices to HVH1; this relationship was
      not evident with C. albicans. In patients with keratosis and acanthosis there was
      a significant lack of correlation between lymphocyte transformation and migration
      inhibition to both HVH1 and C. albicans. In carcinoma the indices of lymphocyte
      transformation and migration inhibition to HVH1 and C. albicans were depressed.
      Furthermore, a significant negative correlation was found between lymphocyte
      transformation and migration inhibition to HVH1, unlike the positive correlation
      in control subjects. Complement fixing antibodies to HVH1, HVH2, cytomegalovirus
      and adenovirus, and fluorescent antibodies to C. albicans failed to show a
      significant change in titre in any one group of subjects tested. The results
      suggest a cell-mediated immune defect in leukoplakia, with a dissociation between
      lymphocyte transformation and macrophage migration inhibition to HVH1 and C.
      albicans in cases of keratosis or acanthosis. A specific increase in cell
      mediated immunity to HVH1 in leukoplakia with epithelial atypia and the
      sequential changes argue in favour of a possible participation of HVH1 in
      carcinomatous transformation of some leukoplakias.

PMID- 4351513
TI  - Tomography of the cavernous sinuses.

PMID- 4351512
TI  - Excretion of alpha-foetoprotein in the urine of pregnant rats and hepatoma
      bearing animals.
AB  - Urine of normal rats, pregnant animals and animals bearing chemically induced
      hepatoma was tested with antisera to foetoproteins by the double immunodiffusion
      technique. Antigens were not detected in the urine of normal rats. Alpha
      foetoprotein was demonstrated in the urine of pregnant rats and hepatomabearing
      animals.

PMID- 4351515
TI  - The neural pathways relaying reflex inhibition from semicircular canals to
      extraocular muscles of rabbits.

PMID- 4351516
TI  - Thalamic regulation of synaptic transmission in the ventrolateral nucleus during
      natural sleep and waking.

PMID- 4351514
TI  - [Sleep and cerebral temperature in rat during chronic heat exposure].

PMID- 4351517
TI  - Two negative dorsal root potentials evoke a positive dorsal root potential.

PMID- 4351518
TI  - Influence of the locus coeruleus on transmission in the spinal trigeminal nucleus
      neurons.

PMID- 4351519
TI  - Slow synaptic inhibition: evidence for synaptic inactivation of sodium
      conductance in sympathetic ganglion cells.

PMID- 4351520
TI  - Acetylcholine and slow synaptic inhibition in frog sympathetic ganglion cells.

PMID- 4351521
TI  - Angiotensin as a possible intrarenal hormone in isolated dog kidneys.

PMID- 4351522
TI  - Metastatic ovarian cancer.

PMID- 4351523
TI  - [Case reports of cylindromas].

PMID- 4351524
TI  - Purification of a messenger-specific initiation factor from ascites-cell
      supernatant.

PMID- 4351525
TI  - Reduced Bohr effect in NO-ligated chironomus haemoglobin.

PMID- 4351526
TI  - Interactions of substrates with a purified 4-methoxybenzoate monooxygenase system
      (O-demethylating) from Pseudomonas putida.

PMID- 4351527
TI  - Structure of protocollagen proline hydroxylase from chick embryos.

PMID- 4351529
TI  - IUPAC-IUB commission on biochemical nomenclature (CBN). Nomenclature of iron
      sulfur proteins. 1973 recommendations.

PMID- 4351528
TI  - Biosynthesis of cartilage procollagen.

PMID- 4351531
TI  - Kinetics of the interaction between pig-plasma benzylamine oxidase and substrate.

PMID- 4351530
TI  - Electron-transport chains of Escherichia coli. Reconstitution of respiration in a
      5-aminolaevulinic acid-requiring mutant.

PMID- 4351532
TI  - 86 Rb transport, water and cation concentrations in lenses exposed to polymyxin B
      sulfate.

PMID- 4351533
TI  - [Herpes simplex virus, type II: microbiology and clinical experiences with
      attenuated vaccine].

PMID- 4351534
TI  - EMS-induced mitotic recombination in a diploid, heterozygous for two
      complementing ade2 alleles of Saccharomyces cerevisiae.

PMID- 4351535
TI  - Isozymes of experimentally induced primary sarcomas in the rat.

PMID- 4351536
TI  - Lymphocyte and antibody cytotoxicity to tumor cells measured by a micro- 51
      chromium release assay.

PMID- 4351537
TI  - Periodate induced lymphocyte transformation. I. Inhibition by sulfhydryl reducing
      agents and sugars.

PMID- 4351538
TI  - Induction of systemic delayed hypersensitivity during experimental viral
      infection of the respiratory tract with a myxovirus or paramyxovirus.

PMID- 4351539
TI  - Effects of pyran copolymer on leukemogenesis in immunosuppressed AKR mice.

PMID- 4351540
TI  - Tumors of minor salivary glands. A study of 23 cases.

PMID- 4351541
TI  - Gastrointestinal bleeding and hepatoma. Diagnostic value of celiac angiography.

PMID- 4351542
TI  - Insulinoma in an eighty-year old.

PMID- 4351543
TI  - An attempt to evaluate the influence of neighboring amino acids (n-1) and (n+1)
      on the backbone conformation of amino acid (n) in proteins. Use in predicting the
      three-dimensional structure of the polypeptide backbone of other proteins.

PMID- 4351544
TI  - Spreading depression, sustained potential shifts, and metabolic activity of
      cerebral cortex of cats.

PMID- 4351545
TI  - Bilateral nephroblastoma.

PMID- 4351546
TI  - Fibrous histiocytoma of the scrotum in an infant.

PMID- 4351547
TI  - [Symptoms and therapy of juvenile nasopharyngeal fibroma in childhood].

PMID- 4351548
TI  - Occurrence of (+)-erythro-2,3-dihydroxyhexacosanoic acid in cerebrin from the
      yeast Saccharomyces cerevisiae.

PMID- 4351549
TI  - Sarcomas of the breast.

PMID- 4351550
TI  - Diagnosis of mammary cancer.

PMID- 4351551
TI  - Pathology of mammary carcinoma.

PMID- 4351552
TI  - [Study of the mutability of the ade-1 and ade-2 loci in Saccharomyces cerevisiae
      under the action of ethyl methanesulfonate].

PMID- 4351553
TI  - Segregation kinetics of colicinogenic factor col E1 from a bacterial population
      temperature sensitive for DNA polymerase I.

PMID- 4351554
TI  - [Hereditary defects of fructose and galactose metabolism].

PMID- 4351555
TI  - Kinetics of phosphorylation and dephosphorylation of testis histones and their
      possible role in determining chromosomal structure.

PMID- 4351556
TI  - Stimulation of cAMP synthesis by glucose in a mutant of E. coli B-r.

PMID- 4351557
TI  - [Hormonal determination of human androgenicity. Value of urinary determination of
      androstanediol and testosterone].

PMID- 4351558
TI  - [Bilateral giant lobular emphysema. Radical treatment by simultaneous double
      thoracotomy in a one-month-old infant].

PMID- 4351559
TI  - [Infectious mononucleosis].

PMID- 4351560
TI  - [Erythrocytic dyslipemias. Preclinical aspect].

PMID- 4351562
TI  - Health hazards of silicious material.

PMID- 4351561
TI  - Psychiatric complications of everyday drugs.

PMID- 4351563
TI  - [Hematuria in the infant].

PMID- 4351564
TI  - [Leukemias Fundamental data. Leukemias and viruses].

PMID- 4351565
TI  - [Endocrinology in 1973].

PMID- 4351567
TI  - [Paraneoplasic endocrinopathies].

PMID- 4351566
TI  - [Current data on plasmatic androgens].

PMID- 4351568
TI  - Metabolic alterations after chronic exposure to  -chlordane.

PMID- 4351569
TI  - [Ultrastructural study of anterior pituitary secretion].

PMID- 4351570
TI  - [Effects of metopirone on growth hormone, glycemia, and plasma insulin].

PMID- 4351571
TI  - Stereophotogrammetric techniques for measurements of the eye ground. An analysis
      of the correlation and variation of parameters measured from the optic cup and
      disc in 115 subjects.

PMID- 4351572
TI  - Hydrosmotic effect of angiotensin II: isolated toad skin.

PMID- 4351573
TI  - Increased cardiovascular reactivity after bilateral nephrectomy in the rat.

PMID- 4351574
TI  - The action of trypan blue on intraparticulate hydrolysis in liver phagolysosomes
      and on a lysosomal enzyme. The linking of the dye to proteins.

PMID- 4351575
TI  - Age factor and the pattern of change in craniofacial structures.

PMID- 4351576
TI  - Growth standards for the tibia and radius in children aged one month through
      eighteen years.

PMID- 4351577
TI  - Norms of size and annual increments of six anatomical measures of the cranium in
      boys and girls from four to fifteen years of age.

PMID- 4351578
TI  - Osteoporotic bone loss in two prehistoric Indian populations.

PMID- 4351579
TI  - The dating of Lantian man and his significance for analyzing trends in human
      evolution.

PMID- 4351581
TI  - Parathyroid hormone receptor in bovine kidney cortex plasma membranes.

PMID- 4351580
TI  - Uptake of vitamin B 12  by phytohaemagglutinin-transformed lymphocytes.

PMID- 4351582
TI  - A function of synovial membrane of normal and diseased humans in relation to the
      movement of small-molecular-weight ions.

PMID- 4351584
TI  - Stimulation of H-3-leucine incorporation into the proinsulin and insulin fraction
      of isolated pancreatic mouse islets in the presence of glucagon, theophylline and
      cyclic AMP.

PMID- 4351583
TI  - Pancreatic islet transplantation in the rat.

PMID- 4351585
TI  - Cross relationships among 37 rhinoviruses demonstrated by virus neutralization
      with potent monotypic rabbit antisera.
AB  - Antisera produced in rabbits to 37 rhinovirus (RV) types have been examined for
      antibody to the 36 corresponding heterologous types. Reciprocal neutralization
      was noted between RV types 2 and 49 and RV types 13 and 41. Five additional
      monotypic rhinoviral rabbit antisera neutralized one heterologous rhinovirus.
      Neutralizing antibody titers against heterologous RV serotypes were similar to
      those shown in the RV 1A, 1B and RV 9, 32 reciprocal cross-reactions, and would
      not be expected to result in false identification of serotypes. Comparison of
      neutralizing antibody titers and neutralization rate constants in serial serum
      specimens of immunized rabbits showed that antibody response to the immunizing RV
      type and the cross-reacting type followed a similar time pattern.

PMID- 4351586
TI  - Guinea pig herpes-like virus infection. I. Antibody response and virus
      persistence in guinea pigs after experimental infection.
AB  - Guinea pigs, experimentally infected with guinea pig herpes-like virus produced
      antibodies which were detectable by indirect hemagglutination (IHA), complement
      fixation (CF), and neutralization tests. The IHA test appeared to be a more
      sensitive method than the CF or neutralization test for determining antibody
      response in guinea pigs immediately after infection, but the IHA method was not
      suitable for the detection of antibody in animals receiving small doses of virus.
      Antibody titers obtained by CF tests were generally higher than those obtained by
      the neutralization test, and they followed the same time course when individual
      animals were studied serially. Intracardiac inoculation produced the best
      antibody response in guinea pigs when compared with other routes of infection.
      Guinea pigs infected by the intraperitoneal, intranasal, or oral route showed
      rising antibody titers but the levels were low. Infectious virus was isolated
      from and persisted in all inoculated animals in the presence of antibody
      regardless of the route of inoculation. Recovery of infectious virus required
      cultivation or cocultivation of tissue cells containing virus. The administration
      of antilymphocyte sera delayed the appearance of IHA antibody but had no effect
      on antibodies determined by the CF- and neutralization tests.

PMID- 4351587
TI  - Guinea pig herpes-like virus infections. II. Antibody response and virus
      persistence in mice and rabbits.
AB  - Mice inoculated with guinea pig herpes-like virus produced minimal, if any,
      antibody response, and no virus was isolated from the inoculated animals 64 days
      after administration. The antibody response in rabbits inoculated with the same
      virus was prompt and reached a high level within 14 to 29 days regardless of the
      site of inoculation. Long-term persistence of viremia was observed only in
      intravenously inoculated rabbits; a brief period of viremia was observed in
      intraperitoneally inoculated rabbits, but no viremia was obtained in rabbits
      inoculated by the subcutaneous route. Maternal antibody was transferred readily
      to offspring; however, transference of infectious virus from mother to offspring
      was demonstrable in only one of 75 fetuses tested.

PMID- 4351588
TI  - Interaction of lymphoid and nonlymphoid cells with the lymphocytosis-promoting
      factor of Bordetella pertussis.
AB  - The activity of soluble lymphocytosis-promoting factor (LPF) from Bordetella
      pertussis decreased after brief in vitro incubation with lymphoid cells or
      erythrocytes. The LPF activity was found to be associated with the cells used,
      and injection of the cells produced a leukocytosis and lymphocytosis which
      completely accounted for the loss of soluble activity. Attachment of LPF to cells
      was found to be reversible in vitro. It is suggested that reversible binding
      occurs in vivo.

PMID- 4351590
TI  - A calcium-sensitive lanthanum inhibition of amoeboid movement.

PMID- 4351589
TI  - Naloxone and the narcotic abuser: a low-dose maintenance program.

PMID- 4351591
TI  - Colony formation by chicken hematopoietic cells and virus-induced myeloblasts.

PMID- 4351592
TI  - [Differential diagnosis of peripheral nerve diseases in children].

PMID- 4351593
TI  - [Diagnosis and therapy of hair diseases. Trichography for the differential
      diagnosis of alopecia].

PMID- 4351594
TI  - [Some physiological differences between saprophytic and phytopathogenic
      fluorescent bacteria of the genus Pseudomonas].

PMID- 4351595
TI  - [Immunofluorescent analysis of the structural proteins of type I Adenovirus].

PMID- 4351596
TI  - Immune status of children one to four years of age as determined by history and
      antibody measurement.

PMID- 4351598
TI  - Conference and workshop on cellular immune reactions to human tumor-associated
      antigens. Introduction.

PMID- 4351597
TI  - Mechanisms of lithium action.

PMID- 4351600
TI  - Neurilemmoma of the facial nerve.

PMID- 4351599
TI  - [Experimental clinical study of leukocyte interferon and aminoadamantane in
      adenoviral conjunctivitis].

PMID- 4351602
TI  - [Responses of fungiform papilla of frog's tongue to tactile and electrical
      stimulation--on the receptor synapse of taste organ].

PMID- 4351601
TI  - Effectiveness of extended aftercare in the treatment of alcoholism.

PMID- 4351604
TI  - [Facial angiography in neoplasms of the ear, nose and throat].

PMID- 4351605
TI  - [Neurologic symptoms in juvenile angiofibromas of the base of the skull].

PMID- 4351606
TI  - [Insulomas. Value of precise morphologic diagnosis].

PMID- 4351603
TI  - [General and local hormone therapy in otorhinolaryngology].

PMID- 4351607
TI  - Subgroup classification of feline leukemia and sarcoma viruses by viral
      interference and neutralization tests.

PMID- 4351608
TI  - Analysis on the reproducing and cell-transforming capacities of a temperature
      sensitive mutant (ts 334) of avian sarcoma virus B77.

PMID- 4351609
TI  - Immunological characterization of a low molecular weight polypeptide of murine
      leukemia virus.

PMID- 4351610
TI  - RNA species obtained from clonal lines of avian sarcoma and from avian leukosis
      virus.

PMID- 4351612
TI  - Complementation of transforming functions by temperature-sensitive mutants of
      avian sarcoma virus.

PMID- 4351611
TI  - Poly(rI) more important than poly(rC) in the interferon induction process by
      poly(rI)-poly(rC).

PMID- 4351613
TI  - The synthesis of complementary ribonucleic acid during infection with LSc
      poliovirus.

PMID- 4351614
TI  - Characterisation of temperature-sensitive mutants of herpes simplex virus type 2.
      Growth and DNA synthesis.

PMID- 4351616
TI  - Prophage deletion mapping of bacteriophage Mu-1.

PMID- 4351615
TI  - A structural model for picornaviruses as suggested from an analysis of urea
      degraded virions and procapsids of coxsackievirus B3.

PMID- 4351617
TI  - Cytomegalovirus infection: a seroepidemiologic study of a recruit population.

PMID- 4351618
TI  - Epidemiologic and clinical observations in six outbreaks of viral disease in a
      kibbutz, 1968-1971.

PMID- 4351619
TI  - Variant angina associated with angiographically demonstrated coronary artery
      spasm and REM sleep.

PMID- 4351621
TI  - [Aminomethylation of geminal dialkyl sulfonylakanes. 40. Alpha halogenated
      amines. 19. N-alpha halogenalkyl-carbonic acid amides].

PMID- 4351620
TI  - Ultrastructural study of two gonadotrophs in rats bearing an adrenocortical
      carcinoma (Snell 494).
AB  - Two morphologically distinct gonadotrophs have been identified in the anterior
      pituitary of rats bearing the Snell 494 tumor. Type 1 gonadotrophs first showed
      ultrastructural alterations at 4 weeks after implantation of the tumor. Numerous
      large 300 to 600 mmu granules appeared in type 1 cells. The opacity of the
      granules was variable, and they sometimes contained non-membrane-bounded
      spherical inclusions. These granules were dispersed among more electron-opaque,
      200-mmu granules usually seen in gonadotrophs. A third granule approximately 500
      to 600 mmu in diameter was apparently a lysosome-derived structure. Type 2
      gonadotrophs first showed changes after 4 weeks, but the alterations were
      especially prominent by 8 to 10 weeks. No large granules characteristic of type 1
      cells were seen in type 2 cells. By 8 to 10 weeks, very few 200-mmu granules were
      observed in the cytoplasm of type 2 cells. The endoplasmic reticulum was dilated
      in most type 2 cells; frequently, the cisternae were dilated considerably,
      forming large lake-like areas. Hypertrophic rough endoplasmic reticulum and the
      presence of intracisternal granules within cisternae of the rough reticulum
      suggest that type 2 cells were stimulated by the tumor. Changes in gonadotrophs
      were undoubtedly produced by the large amount of corticosterone secreted by the
      tumor. The corticosterone secreted by the tumor. The corticosterone may well act
      directly on the hypothalamo-hypophyseal axis or it could act indirectly on the
      ovary; ovarian steroids would then exert a feedback effect. The ovary was
      atrophic and did not contain maturing Graafian follicles or corpora lutea. In
      somatotrophs, the number of secretory granules increased, probably reflecting
      suppression of hormonal release by corticosterone.

PMID- 4351622
TI  - [Alkoxymethyl-disulfone-alkanes].

PMID- 4351623
TI  - Virus cross-infection in paediatric wards.
AB  - In a survey of virus cross-infection in paediatric wards there were 15 cross
      infections due to respiratory syncytial (R.S.) virus and 16 due to influenza A,
      both during a four-month period, and 19 due to parainfluenza viruses over two
      years. The illnesses produced by these infections acquired in hospital ranged
      from a slight cold to severe pneumonia: in 17 of the 50 cases the illness
      involved the lower respiratory tract. A measure of cross-infection frequency in
      the form of a "cross-infection rate" has been devised, and it is suggested that
      this can be used to assess the influence of factors such as ward design and
      admission policy on the frequency of cross-infection.

PMID- 4351624
TI  - Herpes simplex virus type 2 in acute aseptic meningitis.

PMID- 4351625
TI  - Differences between cerebellar mossy and climbing fibre responses to natural
      stimulation of forelimb muscle proprioceptors.

PMID- 4351626
TI  - Visual cortical units associated with phasic activity in REM sleep and
      wakefulness.

PMID- 4351627
TI  - Glial metabolism: alteration by potassium levels comparable to those during
      neural activity.

PMID- 4351628
TI  - Enhanced striatal acetylcholine release by chlorpromazine and its reversal by
      apomorphine.

PMID- 4351629
TI  - Cholinergic neurons: effect of acute septal lesion on acetylcholine and choline
      content of rat hippocampus.

PMID- 4351631
TI  - Propagation of afterdischarges elicited in thin brain sections in artificial
      media.

PMID- 4351630
TI  - [Xanthomatosis as a symptom of hyperlipidemic metabolic disorders. Relationship
      of the morphological picture to the lipid of three patients].

PMID- 4351632
TI  - Effects of neuromuscular activity on choline acetyltransferase and
      acetylcholinesterase.

PMID- 4351634
TI  - Relationships between pre- and postsynaptic effects of A and C fiber inputs to
      dorsal horn of M. mulatta.

PMID- 4351633
TI  - Olivo-cochlear inhibition during physostigmine-induced activity in the pontine
      reticular formation in the decerebrate cat.

PMID- 4351635
TI  - In vivo destruction of tumor cells by an indirect cell-mediated immune mechanism.

PMID- 4351636
TI  - Biological testing of leukaemic lesions of ICRC mice for possible viral activity.

PMID- 4351637
TI  - Delayed effects of a single treatment of hydroxyurea to newborn mice.

PMID- 4351638
TI  - Comparison of in vitro antiamoebic activity of MK 910 with metronidazole,
      intestopan and enterovioform.

PMID- 4351639
TI  - Antibodies to phospholipids in human tuberculous sera.

PMID- 4351640
TI  - Basement membrane antigens combining with antisera to human glomerular asement
      membrane and lymphocytes.

PMID- 4351641
TI  - Neoplasm of mixed mesenchymal and neuroepithelial origin: liposarcomatous
      meningioma combined with gliomas.
AB  - A case is reported of an intracranial neoplasm of mixed mesenchymal and
      neuroepithelial (glial) origin occurring in the parieto-parasagittal region of
      the brain of a 19 year old man. A meningioma with liposarcomatous and
      psammomatous components comprised the mesenchymal part of the combined tumour.
      The neuroepithelial portion was composed of mixed ependymoma and astrocytoma. The
      combined neoplasm had the gross appearances and several microscopic features of
      giant-celled glioblastoma, giant cell sarcoma, and monstrocellular sarcoma. The
      findings suggest that these tumours have a mixed mesenchymal and neuroepithelial
      origin.

PMID- 4351643
TI  - False-positive monospot or rubella and mononucleosis.

PMID- 4351642
TI  - Constituents of Cannabis sativa L. 3. Clear and discrete separation of
      cannabidiol and cannabichromene.

PMID- 4351644
TI  - The initiation of a "metabolic window" in the surface of host erythrocytes by
      Plasmodium berghei NYU-2.

PMID- 4351646
TI  - Epithelial tumours of the salivary glands.

PMID- 4351645
TI  - Regulation of cholesterol biosynthesis in rat liver after the administration of N
      2-fluorenylacetamide.

PMID- 4351647
TI  - [Effect of biotin and desthiobiotin on the growth and formation of polymyxin M by
      Bacillus polymyxa Ross].

PMID- 4351648
TI  - [Lethal action of ultraviolet and gamma irradiation on some species of
      Dematiaceae].

PMID- 4351650
TI  - [Impulse reactions of neurons of the frog midbrain auditory center to exposure to
      acoustic stimuli of different duration].

PMID- 4351649
TI  - [Enterovirus inhibitors in human sera].

PMID- 4351651
TI  - [The dynamic characteristics of cat superior colliculus evoked potentials].

PMID- 4351653
TI  - [Synaptic processes in neurons of the cervical division of the cat spinal cord
      upon stimulation of the propriospinal tracts of the dorsolateral funiculus].

PMID- 4351652
TI  - [Short-latent responses of rat lateral geniculate body neurons to electrical
      stimulation of the optic tract].

PMID- 4351654
TI  - [The multiplicity of pacemaker zones in snail neurons].

PMID- 4351655
TI  - [Value of the capillary and venous phases in the diagnosis of the type of brain
      tumors].

PMID- 4351656
TI  - [Angiographic picture of supratentorial gliomas in capillary and venous phases].

PMID- 4351657
TI  - [Experimental myasthenia. Electrophysiological studies].

PMID- 4351658
TI  - [New procedure for the standardization of angiotensin].

PMID- 4351659
TI  - [Studies on the amount of plasma antidiuretic activity and of Porter-Silver
      chromogens in alcoholic delirium and in acute phenothiazine poisoning].

PMID- 4351660
TI  - Brief exposure of bacteria to topical antibiotics.

PMID- 4351661
TI  - Tissue response to ceramic foam dust following intratracheal and intraperitoneal
      administration.

PMID- 4351663
TI  - [Scientific principles of the prevention of foot-and-mouth disease].

PMID- 4351664
TI  - [Study of transformation in microorganisms].

PMID- 4351662
TI  - Effects of drugs or hepatotoxins on the relation between drug-metabolizing
      activity and phospholipids in hepatic microsomes during choline deficiency.

PMID- 4351665
TI  - [Properties of Cl. perfringens type A isolated from chickens].

PMID- 4351666
TI  - [Change in some properties of adenovirus type 12 following UV irradiation].

PMID- 4351667
TI  - [Immunological characteristics of the blood serum of animals receiving beta
      naphthylamine].

PMID- 4351668
TI  - [Effect of group or isolated maintenance of mice on the development of
      transplantable tumors].

PMID- 4351669
TI  - [Comparative electron microscopy studies on the macrogametes of Isospora felis
      and I. rivolta].

PMID- 4351670
TI  - Effects of prostaglandins E 1 , A 1 , and F 2   on renal handling of salt and
      water.

PMID- 4351671
TI  - Control of gluconeogenesis and glycogenolysis in perfused livers of normal mice.

PMID- 4351672
TI  - Micropharmacology of vertebrate neuromuscular transmission.

PMID- 4351674
TI  - Sympathetic mechanisms in blood vessels: nerve and muscle relationships.

PMID- 4351673
TI  - Drug research and human sleep.

PMID- 4351675
TI  - Radioimmunoassay.

PMID- 4351676
TI  - Renal pharmacology, with special emphasis on aldosterone and angiotensin.

PMID- 4351677
TI  - Glucagon infusion following phosphodiesterase inhibition: an experimental study
      of the hemodynamic effects.

PMID- 4351678
TI  - Endocrine disorders of growth in stature.

PMID- 4351679
TI  - Enzyme activity of antigen-stimulated macrophages.

PMID- 4351680
TI  - Photodynamic inactivation in the treatment of experimental herpes simplex
      keratitis.

PMID- 4351681
TI  - Epidemic keratoconjuctivitis.

PMID- 4351682
TI  - Stimulation of corticotropin release.

PMID- 4351683
TI  - [Detection of lipotropin-synthesizing cells by the fluorescent antibody technic].

PMID- 4351684
TI  - [Membrane adenyl cyclase activity in adipose tissue of obese hyperglycemic Bar
      Harbor mice].

PMID- 4351685
TI  - [Comparison between DNA synthesized by enzyme fractions extracted from foot-and
      mouth disease virus and from atypical rat epithelioma cells].

PMID- 4351687
TI  - [Pleomorphic adenocarcinoma].

PMID- 4351689
TI  - [The impotance of direct neural impulses in the regulation of the thyroid gland].

PMID- 4351688
TI  - [Pathology of Cushing's syndrome].

PMID- 4351690
TI  - [Differential diagnosis of the "burning tongue"].

PMID- 4351691
TI  - Mechanism of hypertriglyceridaemia associated with contraceptive steroids.

PMID- 4351692
TI  - A micro-method for the measurement of pharmacologically induced changes in purine
      derivatives.

PMID- 4351693
TI  - Effect of collagenase on human growth hormone and ACTH.

PMID- 4351694
TI  - The prevalence of hyperlipidemia in a natural community.

PMID- 4351695
TI  - A physico-chemical sub-grouping of the mammalian picornaviruses.

PMID- 4351696
TI  - Mobius syndrome with Poland's anomaly.

PMID- 4351697
TI  - Effects of cortisol on evoked potentials and recovery cycles in the rat
      hypothalamus.

PMID- 4351699
TI  - [Immunologic disorders and biochemical disorders in psoriasis].

PMID- 4351698
TI  - Malakoplakia: an electron-microscope and chemical study.

PMID- 4351700
TI  - Pituitary-adrenal influences on behavior: responses to test situation with or
      without electric footshock.

PMID- 4351701
TI  - The climacteric.

PMID- 4351702
TI  - [Illustration of an original radioimmunological method for the determination of a
      renin inhibitor in human plasma].

PMID- 4351703
TI  - [Enzymatic diagnosis of glycolipidosis].

PMID- 4351704
TI  - [Human hepatic alcohol-dehydrogenase heterogeneity, regulation and clinical
      significance of the enzymatic changes].

PMID- 4351705
TI  - [Use of LKB 8600 analyzer for semiautomatic measuring of enzyme kinetics in
      clinical chemistry].

PMID- 4351706
TI  - [Concept of lysosomal damage].

PMID- 4351707
TI  - [Epilepsy and perinatal injury].

PMID- 4351708
TI  - [Cylindroma of the oral cavity (11 cases)].

PMID- 4351711
TI  - [Pathomorphology in infectious rhinotracheitis of calves].

PMID- 4351709
TI  - [Spontaneous and induced neoplasms in aquarium fish].

PMID- 4351710
TI  - Cell culture propagated fowl pox vaccine.

PMID- 4351712
TI  - A comparative ultrastructural study of the effects of chlorphentermine and
      triparanol in rat lung and adrenal gland.

PMID- 4351713
TI  - [Method of selective protection of the gastrointestinal tract in the methotrexate
      treatment of trophoblastic tumors].

PMID- 4351714
TI  - [Importance of tissue culture in the differential diagnosis of pigmented villose
      nodular synovitis and synoviomas].

PMID- 4351715
TI  - [Isoenzyme spectrum of serine transoxymethylase in the liver and in hepatomas].

PMID- 4351716
TI  - Monkeypox and its relevance to smallpox eradication.

PMID- 4351717
TI  - Virilizing adrenal adenoma.

PMID- 4351718
TI  - Microbiochemical analysis of the arterial wall. I. Phosphofructokinase.

PMID- 4351720
TI  - Studies of the mechanisms of carbohydrate-induced lipaemia in normal man.

PMID- 4351719
TI  - [Serum lipoproteins and antilipemic drugs related to clofibrate. Their in vitro
      interaction].

PMID- 4351721
TI  - Functional overlap between "chylomicra" and "very low density lipoproteins" of
      human plasma during alimentary lipaemia.

PMID- 4351722
TI  - Collagen synthesis in thoracic aortas of rabbits with epinephrine-thyroxine
      induced arteriosclerosis.

PMID- 4351723
TI  - An evaluation of cellulose acetate electrophoresis for the determination of human
      plasma lipoprotein patterns.

PMID- 4351724
TI  - Attempt to influence viral mouse leukaemia by simultaneous infection with
      influenza A1 virus.

PMID- 4351726
TI  - The effect of parachlorophenylalanine on the sleep of a methadone addict.

PMID- 4351725
TI  - [Erythrocytic enzymes and chromosome aberrations. Contribution to the
      establishment of the human factorial chart].

PMID- 4351727
TI  - 'Psychopathia Sexualis'.

PMID- 4351728
TI  - Actinomycin D for Wilms's tumour.

PMID- 4351729
TI  - Temperature-induced phase changes in membranes of heart: a contrast between the
      thermal response of poikilotherms and homeotherms.

PMID- 4351730
TI  - Using inpatient staff for aftercare of severely disturbed chronic patients.

PMID- 4351731
TI  - Malignant hepatoma.

PMID- 4351732
TI  - 'Sclerosing haemangioma' of the lung: an alternative view of its development.

PMID- 4351733
TI  - Spin-labeled analogs of local anesthetics.

PMID- 4351734
TI  - Synthesis of 5-trifluoromethyl-2'-deoxyuridine 5'-phosphate and 5-trifluoromethyl
      2'-deoxyuridine 5'-triphosphate.

PMID- 4351735
TI  - DNA synthesis in nucleotide-permeable Escherichia coli cells. VII. Conversion of
      phi chi-174 DNA to its replicative form.

PMID- 4351736
TI  - Reciprocal effects of change of subunit structure on ligand equilibria of
      haemoglobin valency hybrids. Attempted correlation with electron paramagnetic
      resonance spectra.

PMID- 4351737
TI  - Electron paramagnetic studies of nitric oxide haemoglobin derivatives: isolated
      subunits and nitric oxide hybrids.

PMID- 4351739
TI  - "Polymyositis" with involvement of facial and distal musculature. One form of the
      fascioscapulohumeral syndrome?

PMID- 4351738
TI  - Interaction between lambda or phi80 prophage induction and gal operon expression.

PMID- 4351740
TI  - Mental health nursing consultations: some distinctions.

PMID- 4351741
TI  - Anxiety as a manifestation of associated drives and events in a female
      schizophrenic patient.

PMID- 4351742
TI  - The yellow brick road: a legitimate educational pursuit.

PMID- 4351744
TI  - Mental illness and the state (Roche report).

PMID- 4351743
TI  - Development of the co-therapy relationship.

PMID- 4351745
TI  - Speaking out on: second career adds to nurse supply.

PMID- 4351746
TI  - Psychiatric drugs and trends: long acting tranquilizer.

PMID- 4351747
TI  - Delivery of mental health services to children of "resistive" parents.

PMID- 4351748
TI  - Leisure time for the elderly.

PMID- 4351750
TI  - Unilateral ureteral obstruction. A caue of reversible high renin content
      hypertension.

PMID- 4351749
TI  - Small group method on a general hospital nursing unit.

PMID- 4351751
TI  - Uptake and effect of 17 -estradiol on pineal hydroxy-indole-O-methyl transferase
      (HIOMT) activity.

PMID- 4351752
TI  - Thyroidal K + -activated p-nitrophenylphosphatase activity.

PMID- 4351753
TI  - [Use of Tc 99m  as a basis for therapy of toxic goiter].

PMID- 4351754
TI  - Non-repetitive DNA transcription in mouse cells grown in tissue culture.

PMID- 4351756
TI  - Two distinct antigenic components in an Epstein-Barr virus-related early product
      induced by halogenated pyrimidines in non-producing human lymphoblastoid cells.

PMID- 4351755
TI  - Polyadenylate synthesis by extracts from L cells infected with vesicular
      stomatitis virus.

PMID- 4351757
TI  - Quantitative determination of drugs by means of densitometry of thin-layer
      chromatograms. 3. Determination of vitamins D 2  and D 3  in oil and aqueous
      injection solutions in the presence of decomposition products.

PMID- 4351758
TI  - Leprosy--an alternative viewpoint.

PMID- 4351759
TI  - [Extrahepatic biliary duct carcinoma caused by thorotrast].

PMID- 4351760
TI  - Abrasive blasting protective practices study--preliminary survey results.

PMID- 4351761
TI  - The effect of pyrimidine compounds on the potentiation of adenosine inhibition of
      aggregation, on adenosine phosphorylation and phosphodiesterase activity of blood
      platelets.

PMID- 4351762
TI  - Alexia without agraphia or hemianopsia. Anatomical analysis of an autopsied case.

PMID- 4351763
TI  - Hyperlipaemic neuropathy, Experimental study.

PMID- 4351764
TI  - [Primary cancer of the liver in children in Senegal].

PMID- 4351765
TI  - Genetic influence on the renin-angiotensin system: low renin activities in
      hypertension-prone rats.

PMID- 4351766
TI  - Intrarenal role of angiotensin II. Homeostatic regulation of renal blood flow in
      the dog.

PMID- 4351767
TI  - Variations in adrenergic innervation and contractile responses of the rabbit
      saphenous artery.

PMID- 4351768
TI  - The sudden infant death syndrome.

PMID- 4351769
TI  - [Cyclic adenosine-3',5'-monophosphate as the intracellular mediator of hormonal
      action].

PMID- 4351770
TI  - The action and interaction of diphenhydramine (Benadryl) hydrochloride at the
      neuromuscular junction.

PMID- 4351771
TI  - Measurement of plasma renin substrate by radioimmunoassay of angiotensin. I.
      Concentration in syndromes associated with steroid excess.

PMID- 4351772
TI  - Studies about unconjugated androstenediol in human peripheral plasma.

PMID- 4351773
TI  - Effect of hypopituitarism and ACTH on the urinary excretion of norepinephrine in
      man.

PMID- 4351774
TI  - Adenosine 3',5'-monophosphate in amniotic fluid from normal pregnancy.

PMID- 4351775
TI  - Nocturnal patterns of serum gonadotropins during the menstrual cycle.

PMID- 4351776
TI  - Effect of hydrocortisone and corticotropin on glucose-induced insulin and
      proinsulin secretion in man.

PMID- 4351778
TI  - Inference of refractory period, temporal summation, and adaptation from behavior
      in chronic implants: midbrain pain systems.

PMID- 4351777
TI  - Dexamethasone-suppressible hyperaldosteronism.

PMID- 4351779
TI  - Behavioral measurements of the neural poststimulation excitability cycle in the
      lateral hypothalamic eating system of the rat.

PMID- 4351780
TI  - The role of type specific and cross reacting structural antigens in the
      neutralization of herpes simplex virus types 1 and 2.

PMID- 4351781
TI  - Further evidence for two loci which control susceptibility of fowl to RSV(RAV-O).

PMID- 4351782
TI  - 2,3-Erythro-dihydroxyhexacosanoic acid and homologs: isolation from yeast
      cerebrin phosphate and determination of their structures.
AB  - Homologs of methyl esters of very polar fatty acids were obtained by methanolysis
      of cerebrin phosphate isolated from baker's yeast. The major ester component was
      isolated by preparative gas-liquid chromatography and was found to be 2,3
      dihydroxyhexacosanoic acid as deduced from the mass spectra of its trimethylsilyl
      ether and isopropylidene derivative, reaction with periodate, and comparison of
      its chromatographic behavior with that of synthetic erythro- and threo-dihydroxy
      acids. Its infrared spectrum supported the above conclusions. From their
      retention times by gas-liquid chromatography, the homologs were found to be
      saturated, unbranched 2,3-dihydroxy fatty acids with 24-27 carbon atoms. The
      synthesis of the new fatty acids, erythro- and threo-2,3-dihydroxyhexacosanoic
      acids, is also reported. A method for separating trans-2-hexacosenoic acid, a key
      intermediate of the above synthesis, and its isomer, trans-3-hexacosenoic acid,
      both formed by dehydrobromination of 2-bromohexacosanoic acid, is also described.

PMID- 4351783
TI  - Metabolic fate of rat and human lipoprotein apoproteins in the rat.
AB  - The fate of (125)I-labeled apolipoproteins was studied in vivo in rats that had
      received intravenous injections of (125)I-labeled rat HDL and (125)I-labeled
      human HDL, LDL, and VLDL. Plasma decay curves of rat and human HDL were
      exponential with similar half-lives in the circulation (11-12 hr). After
      injection, low molecular weight apolipoproteins (apoLP-alanine of human HDL and
      fraction HS-3 of rat HDL) were found to redistribute to other lipoproteins,
      predominantly VLDL. Decay curves of individual HDL proteins were constructed
      after lipoprotein fractionation, delipidation, and polyacrylamide gel
      electrophoresis. It was found that the half-lives of the different HDL
      apoproteins were not identical. A major rat HDL protein (52% of total counts) had
      a circulating half-life (t((1/2))) of 12.5 hr. Two others had a t((1/2)) of 8-9
      hr while the t((1/2)) of several others was 11-12 hr. The t((1/2)) of three well
      characterized human HDL apoproteins, apoLP-glutamine I, apoLP-glutamine II, and
      apoLP-alanine, were 13.5, 9.0, and 15.0 hr, respectively. The fate of (125)I
      labeled human VLDL and LDL apoproteins in rats was similar to that described
      previously in humans. After injection of (125)I-labeled human VLDL into rats,
      apoLP-glutamic acid and apoLP-alanine rapidly transferred to rat HDL and were
      lost thereafter from the circulation from both VLDL and HDL. The apoLDL moiety of
      human VLDL moved metabolically to the LDL density range (d = 1.019-1.063) through
      a lipoprotein of intermediate density (d = 1.006-1.019).

PMID- 4351784
TI  - Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in
      homogenates of hog aorta.
AB  - Homogenates and subcellular fractions of the intimamedia of hog aorta have been
      prepared and examined for the presence of the enzymes catalyzing the conversion
      of acetyl CoA to squalene. Enzyme activities effecting the conversion of acetyl
      CoA to 3-hydroxy-3-methylglutarate (HMG); HMG CoA to mevalonic acid; mevalonic
      acid to 5-phosphomevalonic acid, 5-pyrophosphomevalonic acid, and isopentenyl
      pyrophosphate; isopentenyl pyrophosphate to farnesyl pyrophosphate; and farnesyl
      pyrophosphate to squalene have been demonstrated in these homogenates. The
      overall conversion of mevalonate to squalene has also been demonstrated with
      recombined fractions of hog aorta homogenates. Data are also presented that
      suggest that phosphatases present in the crude homogenates act to cleave farnesyl
      pyrophosphate to farnesol, and phospho- and pyrophosphomevalonate to mevalonate.

PMID- 4351786
TI  - Release of transmitters into the perfused third cerebral ventricle.

PMID- 4351787
TI  - Evoked transmitter release at the frog neuromuscular junction in very low calcium
      solutions.

PMID- 4351785
TI  - A comparison of the effects of adenosine triphosphate with noradrenaline and with
      the inhibitory potential of the guinea-pig taenia coli.
AB  - 1. The response of the smooth muscle of the guinea-pig taenia coli to adenosine
      triphosphate (ATP) and related substances was compared with that to noradrenaline
      and dopamine. The effect of these substances on the inhibitory potential was
      investigated.2. ATP in concentration of 10(-6)-10(-5)M suppressed the spontaneous
      spike and relaxed the preparation. ATP in a concentration higher than 10(-4)M
      hyperpolarized the membrane, reduced the membrane resistance and decreased the
      inhibitory potential.3. Effects of noradrenaline (5 x 10(-6)M) and of dopamine (5
      x 10(-4)M) were similar to those of ATP (10(-3)M). However, the effects of
      catecholamines were reduced in Cl-deficient solution and blocked by phentolamine
      (3.5 x 10(-6)M), while the effects of ATP were unaffected.4. A high concentration
      of phentolamine (3.5 x 10(-4)M) almost abolished the inhibitory potential as well
      as the effects of ATP. The inhibitory potential and the effect of high
      concentration of ATP (10(-3)M) were not impaired by imidazole (50 mM).5.
      Adenosine diphosphate, adenosine monophosphate and adenosine produced effects
      essentially similar to those of ATP. However, their potency was less compared
      with ATP.6. These electrophysiological observations support the hypothesis that
      ATP may be the transmitter of the non-adrenergic inhibitory nerves in the taenia
      coli. No evidence against the hypothesis was obtained.

PMID- 4351788
TI  - Advances in lipoprotein research: biochemical and clinical aspects.

PMID- 4351789
TI  - [Chlorpropamide in diabetes insipidus].

PMID- 4351790
TI  - Biochemical mechanisms in myelin deficient mutants.

PMID- 4351792
TI  - [Umbilical hepatography with an oily contrast medium].

PMID- 4351791
TI  - Adenosine release from isolated fat cells and its significance for the effects of
      hormones on cyclic 3',5'-AMP levels and lipolysis.

PMID- 4351793
TI  - [Association of congenital malformation and cytomegalic inclusion disease.
      Anatomo-clinical study of 18 cases].

PMID- 4351794
TI  - [Estradiol binding in normal and neoplastic tissue].

PMID- 4351795
TI  - [Value of radiotherapy in malignant salivary gland tumors].

PMID- 4351796
TI  - [Pre-invasive breast cancer detected by way of cytological examination of nipple
      discharge].

PMID- 4351797
TI  - [The use of ion-selective electrodes in the Lipiodol test for the study of fat
      absorption].

PMID- 4351798
TI  - Sugar transport in normal and Rous sarcoma virus-transformed chick-embryo
      fibroblasts.
AB  - 3-O-methylglucose (3-OMeG) is a nonmetabolizable glucose analog and is,
      therefore, suitable for transport studies. 3-OMeG and glucose compete for entry
      into normal and Rous sarcoma virus (RSV)-transformed chick-embryo fibroblasts.
      Therefore, 3-OMeG can be used to study the transport of glucose in these cells.
      Chickembryo fibroblasts infected and transformed by RSV take up 3-OMeG at a
      faster rate than uninfected cells when both cell types are growing at the same
      rate. The rate of efflux of 3-OMeG also increases after transformation. When the
      uptake and the efflux reach a steady state, the intracellular concentration of 3
      OMeG is equal to the concentration in the medium. This finding indicates that
      glucose is transported across the plasma membrane by facilitated diffusion. The
      V(max) of the transport system for 3-OMeG increases after transformation, while
      the affinity or K(m) of the system remains unchanged. We conclude that viral
      transformation causes a change in the plasma membrane of the infected cells by
      increasing either the number of molecules or the mobility of the glucose carrier.

PMID- 4351799
TI  - Conversion of neutral to alkaline liver fructose 1,6-bisphosphatase: changes in
      molecular properties of the enzyme.
AB  - Removal of the NH(2)-terminal region of fructose 1,6-bisphosphatase from rabbit
      liver by digestion with subtillisin, or changes in conformation in this region of
      the protein produced by exposure to low concentrations of urea, result in similar
      changes in catalytic and allosteric properties of the enzyme. These changes
      include shift of the pH optimum to more alkaline pH, and loss of sensitivity to
      inhibition by AMP. The conformation changes are monitored by changes in the
      fluorescence of the single tryptophan residue, which is located near the NH(2)
      terminus. Thus, the tryptophan-containing peptide appears to determine the
      functional properties of the native enzyme.

PMID- 4351800
TI  - Roles of calcium, serum, plasma, and folic acid in the control of proliferation
      of normal and Rous sarcoma virus-infected chicken fibroblasts.
AB  - In a culture medium of pH 7.4 and a folic acid concentration of 100 mug/liter
      that contains 5% heat-inactivated chicken plasma rather than serum, the rate of
      proliferation of normal chicken fibroblasts is determined by the concentration of
      calcium. Proliferation, rapid when the calcium concentration is physiological,
      decreases when the calcium concentration is reduced. At a very low calcium
      concentration, in this culture medium, normal fibroblasts are maintained without
      proliferation, whereas those infected with Rous sarcoma virus proliferate
      rapidly. This proliferative inactivity of normal fibroblasts does not involve
      contact-inhibition, since the effect is observed at low, as well as higher,
      culture densities. When a physiological amount of calcium is added to cultures of
      normal fibroblasts that have been maintained in very low calcium-plasma medium
      for 3 days, labeled thymidine uptake and protein synthesis are strongly
      stimulated, and cell division follows. The use of heat-inactivated chicken serum,
      instead of plasma, in this medium appears to strongly sensitize normal
      fibroblasts to the mitogenic action of calcium. In a plasma-containing culture
      medium of physiological calcium concentration and a folate concentration of 5
      mug/liter, neither normal nor Rous sarcoma virus-infected fibroblasts proliferate
      to an appreciable extent. The use of serum, however, instead of plasma results in
      rapid proliferation of both normal and infected cells, as does increase in the
      folate concentration of the plasma-containing medium to 100 mug/liter.The fact
      that while normal fibroblasts are maintained without proliferation in low calcium
      plasma medium, Rous sarcoma virus-infected fibroblasts proliferate rapidly,
      indicates that the effect of calcium is regulatory rather than permissive. These
      results suggest that the proliferation of normal fibroblasts is initiated by a
      cellular function involving calcium, and that the autonomous proliferation of the
      neoplastic fibroblasts results either from increased calcium uptake or from an
      alteration or a hypass of that function. The results also suggest that serum
      contains a mitogenic factor(s) not present in plasma, possibly a "wound hormone"
      for fibroblasts.

PMID- 4351802
TI  - Demonstration of a cell-surface antigen associated with murine sarcoma virus by
      immunoelectron microscopy.
AB  - Cells transformed by murine sarcoma virus have been examined for the presence of
      a new virus-associated cell-surface antigen by immunoelectron microscopy. A
      common antigen has been detected on the surface of nonproductively transformed
      cells that were induced by two different strains of murine sarcoma virus, Kirsten
      and Moloney. This antigen shows crossreaction with cell lines transformed by
      murine sarcoma virus that were produced in two different mammalian species, rats
      and mice. Further, this antigen is distinct from previously described antigens on
      the surfaces of cells infected by murine leukemia virus, on the viral envelope,
      and on the surfaces of spontaneously transformed cell lines or cell lines
      transformed by x-irradiation.

PMID- 4351801
TI  - Nucleation, rapid folding, and globular intrachain regions in proteins.
AB  - Distinct structural regions have been found in several globular proteins composed
      of single polypeptide chains. The existence of such regions and the continuity of
      peptide chain within them, coupled with kinetic arguments, suggests that the
      early stages of three-dimensional structure formation (nucleation) occur
      independently in separate parts of these molecules. A nucleus can grow rapidly by
      adding peptide chain segments that are close to the nucleus in aminoacid
      sequence. Such a process would generate three-dimensional (native) protein
      structures that contain separate regions of continuous peptide chain. Possible
      means of testing this hypothesis are discussed.

PMID- 4351803
TI  - Pineal protein kinase: effect of enzymic phosphorylation on actinomycin D binding
      by, and template activity of, chromatin.
AB  - The ability of protein kinase from bovinepineal gland to phosphorylate calf
      thymus chromatin and thereby to alter the association between chromatin DNA and
      histones was investigated. Phosphorylation of calf-thymus chromatin by pineal
      protein kinase results in an apparent decreased binding between the histones and
      DNA in chromatin, as indicated by (i) an increase in actinomycin D-binding sites
      after phosphorylation and (ii) an increase in the template capacity of the calf
      thymus chromatin after phosphorylation. F(1) histone and F(3) histone are the
      major histone classes in the chromatin that are phosphorylated by the protein
      kinase. These results support the hypothesis that pineal protein kinase may
      function at the transcriptional level.

PMID- 4351805
TI  - Chemotaxis by the nematode Caenorhabditis elegans: identification of attractants
      and analysis of the response by use of mutants.
AB  - The nematode Caenorhabditis elegans is attracted by at least four classes of
      attractants: by cyclic nucleotides, cAMP and cGMP; by anions, Cl(-), Br(-), I(-);
      by cations, Na(+), Li(+), K(+), Mg(+); and by alkaline pH values. The nematode's
      behavioral response to gradients of these attractants involves orientation and
      movement up the gradient, accumulation, and then habitutation. Comparison of the
      tracks of wild-type and mutant animals responding to gradients of attractants
      indicates that sensory receptors in the head alone mediate the orientation
      response and that the direction of orientation is determined by the lateral
      motion of the head. Therefore, the orientation response is a klinotaxis.

PMID- 4351804
TI  - Affinity binding of intact fat cells and their ghosts to immobilized insulin.
AB  - Immobilized insulin, prepared by coupling insulin directly to agarose or through
      hydrocarbon "connecting arms," was demonstrated to be capable of firmly binding
      intact adipocytes and their ghosts. Various lines of evidence indicate that the
      insulin receptor on the plasma membrane, in addition to the insulin coupled to
      the agarose, was responsible for the observed binding. This evidence includes:
      (a) the finding that increasing the "arm" length increased the binding capacities
      of insulin-Sepharose affinity chromatographic columns, (b) specific inhibition
      and reversal by insulin and antiserum to insulin of the binding, as compared to
      lesser effects by other peptide hormones, (c) the indication that only the plasma
      membrane sacs, not the other cellular contaminants in the crude ghosts, are
      capable of binding, and (d) the impairment and restoration of trypsin-sensitive
      membrane binding sites that are also required for insulin biosensitivity. These
      findings support the idea that the insulin receptor is the trypsin-sensitive
      site. By use of the differential buoyant densities of the various cell-bead
      complexes that resulted from the interaction of adipocytes with insulin
      Sepharose, a new procedure was developed to demonstrate and study the binding.
      These complexes could also be demonstrated by interference contrast microscopy.
      Binding readily occurred under conditions favorable for insulin stimulation of
      the cells. By coupling tracer amounts of [(125)I]insulin to Sepharose or insulin
      Sepharose, the effects of anti-insulin antisera, free insulin, and other peptide
      hormones and supplemental factors on the buoyant-density distribution of the
      complexes could be measured, as well as the effects of other ligands coupled to
      Sepharose.

PMID- 4351806
TI  - Carbohydrate catabolism and the enhancement of uptake of galactose in hamster
      cells transformed by polyoma virus.
AB  - Untransformed as well as polyoma virus-transformed hamster cells can be grown
      equally well on a slow catabolite like galactose as on a rapid catabolite like
      glucose. The rate of uptake of galactose is greatly enhanced in the transformed
      cells as compared with untransformed cells, and this enhancement of entry was as
      markedly expressed in galactose-grown cultures as in glucose-grown cultures.
      Since the transformed cultures grown in glucose medium consume practically all of
      their carbohydrate, contrary to the galactose-grown cultures, problems dealing
      with regulation of transport by substrate concentrations have to be dealt with
      also. The galactose captured by the cells accumulates initially as galactose,
      alpha-galactose-1-phosphate, and UDP-galactose. However, after a 24-hr growth on
      a galactose growth medium, the product accumulated was almost exclusively
      galactitol. In spite of the enhancement of entry of galactose into the
      transformed cells, the metabolic pathway becomes stalled even before it has
      reached the stage of glucose-1-phosphate, largely due to a choke of the enzyme
      UDP-galactose-4-epimerase (EC 5.1.3.2). Among the sparse amounts of catabolic
      products generated by the transformed cells from galactose, carbon dioxide
      (allebeit no D-xylose) and lactic acid were found, both of them in much smaller
      amounts than seen if glucose is the carbohydrate source. Also, growth of
      transformed cells on a galactose medium gradually tends to become oriented, a
      phenomenon that could be called "contact promotion." Subsequent addition of
      glucose disturbs the oriented growth and interferes with contact promotion.

PMID- 4351807
TI  - Cytochalasin B: effect on lysosomal enzyme release from human leukocytes.
AB  - The morphological and biochemical consequences of treatment of human peripheral
      blood leukocytes with cytochalasin B were studied. Incubation of human polymorphs
      with cytochalasin B resulted in nuclear and cytoplasmic spreading, but not in
      spontaneous release of lysosomal enzymes. Cytochalasin B inhibited particle
      uptake. Consequently, phagocytic vacuoles were not observed; instead, granule
      contents were discharged directly into the surrounding medium when cytochalasin B
      treated cells were challenged with zymosan particles. Cytochalasin B enhanced the
      release of lysosomal enzymes from human polymorphonuclear leukocytes whether
      these encountered zymosan particles or immune complexes on a nonphagocytosable
      Millipore filter. Cytochalasin B-treated leukocytes thus constitute a model
      system for quantitative study of lysosome fusion. Augmented enzyme release was
      blocked by prior treatment of cells with pharmacological doses of agents that
      influence the accumulation of cyclic nucleotides (cyclic nucleotides themselves,
      prostaglandin E(1)) or by compounds that interfere with microtubule function
      (e.g., colchicine, vinblastine). These observations suggest that one action of
      cytochalasin B on phagocytic cells is to remove the normal constraints to merger
      of granules, either with each other or with the plasma membrane, and that intact
      microtubule function is required for translocation of lysosomes.

PMID- 4351808
TI  - Minor base composition of "70S-associated" 4S RNA from avian myeloblastosis
      virus.
AB  - Using a chemical isotope derivative method, we have determined the minor base
      composition of the "70S-associated" 4S RNA isolated from avian myeloblastosis
      virus. The minor base composition of this "70S-associated" 4S RNA is strikingly
      similar to that of the corresponding "free" 4S RNA of the virion. This minor base
      content, plus the capacity to esterify amino acids, establishes that both of
      these virion 4S RNA fractions contain transfer RNA. The percentage of minor bases
      in virion "70S-associated" 4S RNA is, however, much lower than in "free" 4S
      virion RNA and in myeloblast 4S RNA. The implication is that the "70S-associated"
      4S RNA fraction as isolated herein also contains RNA that is not transfer RNA.
      This latter RNA may represent either degradation products of high molecular
      weight RNA or indigenous 4S RNA of undetermined function.

PMID- 4351809
TI  - Regulation of phosphorylation of a specific protein in toad-bladder membrane by
      antidiuretic hormone and cyclic AMP, and its possible relationship to membrane
      permeability changes.
AB  - Phosphorylation of a specific protein was decreased in intact toad bladders by
      exposure to either antidiuretic hormone or monobutyryl cyclic AMP. The decrease
      in phosphorylation caused by these agents preceded the change in electrical
      potential difference (an indicator of the rate of sodium ion transport) observed
      in response to the same compounds. The addition of cyclic AMP to homogenates of
      toad bladder led to a decrease in phosphorylation of the same, or a similar,
      protein. In subcellular fractionation studies, the effect of cyclic AMP on the
      phosphorylation of this protein was observed in those fractions rich in membrane
      fragments, but not in the nuclear or cell-sap fractions. These and other results
      are compatible with the possibility that the regulation by vasopressin and cyclic
      AMP of sodium and/or water transport in toad bladder may be mediated through
      regulation of the phosphorylation of this specific protein.

PMID- 4351812
TI  - [Etiology of ulnar nerve lesions, an electromyographic analysis of 150 cases].

PMID- 4351810
TI  - A transmissible plasmid controlling camphor oxidation in Pseudomonas putida.
AB  - Earlier papers demonstrated an extensive genetic exchange among fluorescent
      Pseudomonads; this one documents for genes specifying enzymes of peripheral
      dissimilation an extrachromosomal array, segregation, and frequent interstrain
      transfer. An hypothesis is presented of a general mechanism for the formation and
      maintenance of metabolic diversity. The example used, the path of oxidative
      cleavage of the carbocyclic rings of the bicyclic monoterpene D- and L-camphor,
      terminates in acetate release and isobutyrate chain debranching. By transduction,
      two gene linkage groups are shown for the reactions before and after isobutyrate.
      The group for reactions before isobutyrate is plasmid borne, contransferable by
      conjugation, mitomycin curable, and shows a higher segregation rate from cells
      that are multiplasmid rather than carrying a single plasmid. The genes that code
      for isobutyrate and essential anaplerotic and amphibolic metabolism are
      chromosomal. By conjugation plasmid-borne genes are transferred at a higher
      frequency than are chromosomal, and are transferred in homologous crosses more
      frequently than between heterologous species. Most isobutyrate-positive
      fluorescent pseudomonad strains will accept and express the camphor plasmid.

PMID- 4351811
TI  - Acetylcholine receptor and ion conductance modulator sites at the murine
      neuromuscular junction: evidence from specific toxin reactions.
AB  - The perhydro derivative of histrionicotoxin reversibly blocks the excitatory
      ionic transduction system in the synaptic and sarcolemmal membranes of mammalian
      skeletal muscle cells. The efficacy of perhydrohistrionicotoxin as an antagonist
      at the post-synaptic membrane is increased by the transient presence of
      acetylcholine in the endplate of innervated muscles and at extrajunctional
      receptors in denervated muscles. alpha-Bungarotoxin and [(3)H]monoacetyl-alpha
      bungarotoxin block the endplate acetylcholine receptors, each binding to the same
      extent. The effect of bungarotoxin is partially reversible. These
      electrophysiological results, together with the effects of
      perhydrohistrionicotoxin and/or d-tubocurarine on the binding of [(3)H]monoacetyl
      alpha-bungarotoxin at endplates of murine diaphragm muscle and on the
      bungarotoxin-elicited irreversible blockade of neuromuscular transmission,
      suggest that at least two types of sites participate in the synaptic excitation
      by acetylcholine. One site, competitively blocked by bungarotoxin and by curare,
      is presumably the acetylcholine receptor. Binding of bungarotoxin at this site is
      responsible for an irreversible blockade of neuromuscular transmission. The
      second site, competitively blocked by bungarotoxin and perhydrohistrionicotoxin,
      is proposed to be part of the cholinergic ion conductance modulator. Binding of
      bungarotoxin to this site does not result in an irreversible blockade.

PMID- 4351813
TI  - [Pseudotumor cerebri. Benign intracranial pressure].

PMID- 4351815
TI  - Activity of glucoso-6-phosphage gluconeogenesis and dehydrogenase enzymes in
      fertilized and unfertilized loach ova.

PMID- 4351814
TI  - Clinical management of advanced gastrointestinal cancer.

PMID- 4351816
TI  - Biological activities contaminating preparations of phospholipase C ( -toxin)
      from Clostridium perfringens.

PMID- 4351818
TI  - Isolation of Gymnodinium breve toxin from Florida red tide water.

PMID- 4351817
TI  - Venoms and enzymes: effects of permeability of isolated single electroplax.

PMID- 4351819
TI  - Colchicine in avian sodium urate and calcium pyrophosphate microcrystal
      arthritis.

PMID- 4351820
TI  - Application of the technique os isoelectric focusing to the study of human serum
      lipoproteins and their apoproteins.

PMID- 4351821
TI  - Proliferation of vesicular stomatitis virus in leucocytes from rheumatoid
      patients.

PMID- 4351822
TI  - Clinical and laboratory aspects of raised virus antibody titres in systemic lupus
      erythematosus.

PMID- 4351823
TI  - Effect of some adrenal steroid hormones on skin fibroblast replication in vitro.

PMID- 4351824
TI  - 2',3'-Cyclic nucleotide 3'-phosphohydrolase in the developing human brain.

PMID- 4351825
TI  - [Apparently primary myocardiopathies in black Africa].

PMID- 4351826
TI  - Human erythrocyte phosphoribosylpyrophosphate synthetase mutationally altered in
      regulatory properties.

PMID- 4351828
TI  - Activation of endogenous C-type on oncornavirus by 5-bromodeoxyuridine in
      cultured embryonic rat fibroblasts.

PMID- 4351827
TI  - Direct stimulant effect of cyclic AMP and dibutryl cAMP on glycogenolysis by
      hepatocytes in histiotypic culture.

PMID- 4351829
TI  - [Alpha l-fetoprotein in liver diseases and metabolic disorders in children].

PMID- 4351830
TI  - Comment on Wei's theory of synaptic conduction.

PMID- 4351831
TI  - Preganglionic sympathetic activity and baroreceptor responses during hypothermia.

PMID- 4351832
TI  - Postsynaptic potentials in the mesencephalic and pontomedullar reticular regions
      underlying descending limbic influences.

PMID- 4351833
TI  - Antagonistic effects of semicarbazide and pyridoxine on cuneate presynaptic
      inhibition.

PMID- 4351834
TI  - Effect of potassium ions on glucose and phospholipid metabolism in the rat's
      cervical sympathetic ganglia with and without axotomy.

PMID- 4351835
TI  - Regional differences within the caudate nucleus for suppression of extralemniscal
      thalamic units.

PMID- 4351836
TI  - Spontaneous bioelectric activity in long term cultures of the embryonic insect
      central nervous system.

PMID- 4351838
TI  - [Regulation by progesterone of the concentration of its uterine receptors].

PMID- 4351837
TI  - A nucleoside diphosphate phosphohydrolase present in a coated-vesicle fraction
      from synaptosomes of guinea-pig whole brain.

PMID- 4351839
TI  - [Bacteriocin production linked to the presence of a plasmid, in Clostridium
      perfringens, type A].

PMID- 4351840
TI  - [Effects of butter yellow on 6-phosphorylglucose phosphatase activity. Choice of
      the reference basis and interpretation of hypoglycemia].

PMID- 4351841
TI  - [Demonstration of corticotropic cells in the pituitary gland of the green frog,
      Rana esculenta L., by the immunofluorescent technic].

PMID- 4351842
TI  - [Effects of porcine ACTH on arterial hypertension due to norepinephrine in rats].

PMID- 4351843
TI  - Syncardial massage in diabetic and other neuropathies of lower extremities.

PMID- 4351845
TI  - [Psychopharmacology of sleep. II].

PMID- 4351844
TI  - [Vitamin D metabolism and chronic kidney insufficiency].

PMID- 4351846
TI  - The kinetics of the anaerobic reduction of fungal laccase B.

PMID- 4351847
TI  - Specificity of aeromonas aminopeptidase toward oligopeptides and polypeptides.

PMID- 4351848
TI  - Assay of yeast enzymes in situ. A potential tool in regulation studies.

PMID- 4351849
TI  - The inhibitory effect of AMP on the activation reactions of the amino acids
      involved in gramicidin S biosynthesis.

PMID- 4351850
TI  - Enzymes of Bacillus licheniformis in the biosynthesis of Bacitracin A.

PMID- 4351851
TI  - Reaction of sulfenyl halides with cytochrome c. A novel method for heme cleavage.

PMID- 4351852
TI  - Selective cleavage of the single tryptophanyl peptide bond in horse heart
      cytochrome c.

PMID- 4351854
TI  - Cytoplasmic DNA's consisting of unique nuclear sequences in hamster cells. A
      possible role in cell differentiation and oncogenesis.

PMID- 4351853
TI  - An intermediate in the reaction of reduced laccase with oxygen.

PMID- 4351855
TI  - Glycolipid synthesis in baby-hamster-kidney fibroblasts transformed by a
      thermosensitive mutant of polyoma virus.

PMID- 4351856
TI  - Effects of hormones on cyclic AMP release in perfused rat livers.

PMID- 4351858
TI  - In vitro studies on the acylation of 1-O-alkenyl glycero-3-phosphorylethanolamine
      by rat brain preparations.

PMID- 4351857
TI  - Evidence for an insulin receptor in muscle.

PMID- 4351859
TI  - Implications of psychological research for smoking control clinics.

PMID- 4351860
TI  - The impacts of NIMH grants to improve state hospitals.

PMID- 4351861
TI  - The influence of state regulatory processes on mental health programs.

PMID- 4351863
TI  - The proton relaxation enhancement properties of concanavalin A.

PMID- 4351862
TI  - [G.I.P. (gastric inhibitory polypeptide) and the WDHA (Verner-Morrison)
      syndrome].

PMID- 4351864
TI  - Characterization of the specific androgen receptors in the human prostate gland.

PMID- 4351866
TI  - Effect of perphenazine during late pregnancy on prolactin production and
      lactogenesis in the rat.

PMID- 4351865
TI  - Effect of stress and environmental temperature on adrenal function in Rana
      esculenta.

PMID- 4351867
TI  - Effect of human chorionic gonadotrophin on testicular 5 -adnrostane-3 
      hydroxysteroid dehydrogenase, 3 -hydroxydehydroepiandrosterone dehydrogenase and
      alcohol dehydrogenase of immature rats.

PMID- 4351868
TI  - Further studies on the trophic effect of cyclic GMP on rat adrenal cortex.

PMID- 4351869
TI  - Intrarenal teratoma occurring in infancy: report of a case with discussion of
      extragonodal germ cell tumors in infancy.

PMID- 4351871
TI  - Isolation and identification of trachoma and inclusion conjunctivitis agents in
      Melbourne, 1966 to 1972.

PMID- 4351870
TI  - Gas gangrene--a ten-year survey from the Royal Adelaide Hospital.

PMID- 4351872
TI  - [Adenoviral diseases of the eye].

PMID- 4351873
TI  - [Isolation of respiratory syncytial virus. Apropos of a study of an epidemic
      outbreak].

PMID- 4351874
TI  - Treatment of testicular tumors.

PMID- 4351875
TI  - Mesodermal mixed tumor of the corpus uteri.

PMID- 4351876
TI  - [Reticulospinal and propriospinal monosynaptic influences on frog motor neurons].

PMID- 4351877
TI  - [Synaptic processes evoked by intracortical microstimulation in the lumbar motor
      neurons of rats].

PMID- 4351878
TI  - [Loss of information during central summation of local postsynaptic potentials].

PMID- 4351879
TI  - [Biphasic synaptic potentials and the effects of prolonged post-stimulatory
      hyperpolarization in the neurons of the grape snail].

PMID- 4351881
TI  - [The measurement of dust. The physics of dust].

PMID- 4351880
TI  - ECS produced disruption or facilitation of discriminated active avoidance
      performance in rats.

PMID- 4351882
TI  - [The measurement of dust. The physics of dust].

PMID- 4351883
TI  - [Combating dust in iron mines].

PMID- 4351884
TI  - Estrogen-binding to pancreas.

PMID- 4351885
TI  - [Problems of long-term therapy of chronic pyelonephritis].

PMID- 4351886
TI  - [Transfer factor of cellular immunity. Preliminary therapeutic trials during
      specific immunologic deficiencies of an antigen in human clinical practice].

PMID- 4351887
TI  - Modified hormonal control of enzymatic activity in tumors.

PMID- 4351888
TI  - Studies on uterine flushings in the baboon. II. The effect of an intrauterine
      contraceptive device on certain biochemical parameters.

PMID- 4351889
TI  - Trypsin aerosol treatment of pulmonary alveolar proteinosis. Case report.

PMID- 4351890
TI  - [Effects of synthetic TRH in normal subjects].

PMID- 4351891
TI  - [Effect of intravenous injection of synthetic TRH in hypophyseal pathology].

PMID- 4351893
TI  - [Secretion of growth hormone and ACTH in pituitary tumors].

PMID- 4351892
TI  - [Action of neuroleptics on hypothalamo-hypophyso-corticotropic and hypothalamo
      somatotropic functions].

PMID- 4351894
TI  - [Direct investigation of hypophyseal corticotropic function].

PMID- 4351896
TI  - [Dynamic investigations of pituitary function in patients with chromophobe
      pituitary adenoma or with acromegaly].

PMID- 4351895
TI  - [Peripheral myxedema; amenorrhea-galacorrhea; radiologic image of hypophyseal
      adenoma; inhibitable hyper-TSH secretion].

PMID- 4351897
TI  - [Renin-angiotensin-aldosterone system and arterial hypertension in acromegaly].

PMID- 4351898
TI  - [Extensive pituitary tumors with corticotropic secretion (ultrastructural
      study)].

PMID- 4351899
TI  - [Diaphragmatic adrenocortical tumor].

PMID- 4351900
TI  - Effect of sodium n-dipropylacetate on audiogenic seizures and brain  
      aminobutyric acid level.

PMID- 4351902
TI  - The uptake of (14 C) glucose into rabbit ear cartilage proteoglycans isolated by
      differential extraction and by collagenase digestion.

PMID- 4351901
TI  - Isoproterenol and glucagon effects in perfused hearts from spontaneously
      hypertensive and normotensive rats.

PMID- 4351903
TI  - [Statistical analysis of the neuronal reactions of the sensorimotor area of the
      cortex in the development of a temporary connection].

PMID- 4351904
TI  - The biochemistry of ferritin.

PMID- 4351905
TI  - A genetically determined disorder with features both of thalassaemia and
      congenital dyserythropoietic anaemia.

PMID- 4351906
TI  - The Hermansky-Pudlak syndrome: inclusions in circulating leucocytes.

PMID- 4351907
TI  - Hypophysis and function of pancreatic islets. II. The effect of substitution with
      growth hormone and corticotrophin on insulin secretion and biosynthesis of
      proinsulin and insulin in isolated pancreatic islets of hypophysectomized rats.

PMID- 4351908
TI  - [Metabolism of amidopyrine and barbiturates in the liver in toxic hepatitis].

PMID- 4351909
TI  - Toxicology's need for new analytical methods.

PMID- 4351911
TI  - A radiographic study of the growth of the rat pelvis.

PMID- 4351912
TI  - Antiparasitic nitroimidazoles. 3. Synthesis of 2-(4-carboxystyryl)-5-nitro-1
      vinylimidazole and related compounds.

PMID- 4351910
TI  - Distribution and localization of sites of gamma aminobutyric acid metabolism in
      the adult rat brain.

PMID- 4351913
TI  - Synthesis and biological evaluation of LH and FSH releasing hormone and its
      analogs.

PMID- 4351914
TI  - Synthesis and biological effects of 13-dehydro derivatives of natural
      prostaglandin F 2   and E 2  and their l5-epi enantiomers.

PMID- 4351915
TI  - Influence of protein under- and overnutrition on spontaneous tumor prevalence in
      the rat.

PMID- 4351916
TI  - The effects of corticosterone, 18-OH-DOC, DOC and 11 -hydroxyprogesterone on the
      adrenal pituitary axis of the stressed rat.

PMID- 4351917
TI  - In vivo and in vitro testosterone metabolism by the androgen insensitive rat.

PMID- 4351919
TI  - Gas chromatographic determination and mass spectrometric identification of
      oestrogens in normal human placental tissue at term.

PMID- 4351918
TI  - Differences between rats and chickens in response to synthetic
      glucocorticosteroid.

PMID- 4351920
TI  - Metabolism of ( 3 H)-testosterone by the adrenal of the dog: the action of ACTH.

PMID- 4351921
TI  - Tumours of the glomus jugulare.

PMID- 4351922
TI  - [Behavior of corticotropinemia and cortisolemia in insulin-induced hypoglycemia.
      Evaluation of plasma ACTH with a radioimmunological method].

PMID- 4351923
TI  - [Neurogenic tumors of the mediastinum].

PMID- 4351924
TI  - Hydrocortisone and vascular reactivity in dogs with hemorrhagic shock.

PMID- 4351925
TI  - Right-sided abscess in the region of the diaphragm associated with
      bronchiectasis.

PMID- 4351927
TI  - [Embolism of the lungs and changes in their function following lymphography
      (review of the Soviet and foreign literature)].

PMID- 4351926
TI  - Humoral factors influencing cell-mediated immune responses to tumour-associated
      antigens.

PMID- 4351929
TI  - [Chemical characteristics of DDII phage and its nucleic acid].

PMID- 4351928
TI  - [Activation of latent adenovirus infection of human tonsil cell cultures by
      superinfection with adenoviruses of the latent subgroup].

PMID- 4351930
TI  - [Experimental study of the action of different interferonogens in herpetic
      infection].

PMID- 4351931
TI  - [Capacity of ribosomes to despiralize paramyxovirus nucleocapsid in in vitro
      experiments].

PMID- 4351932
TI  - [Detection of minimal concentrations of viruses in large volumes by
      ultrafiltration through soluble Lanthanum-aluminum-alginate ultrafilters].

PMID- 4351933
TI  - Descending pathways in the spinal cord affecting sympathetic activity in
      spinalized cats.

PMID- 4351934
TI  - The problem of "sympathetic tone" with particular respect to sleep.

PMID- 4351935
TI  - Mathematical model of the neuron used for analysis of periodically modulated
      patterns of discharges.

PMID- 4351936
TI  - The changes of noradrenaline in sympathetic ganglia and in the brain under reflex
      and humoral influences.

PMID- 4351937
TI  - Quantitative aspects of the release of noradrenaline from peripheral adrenergic
      neurones.

PMID- 4351938
TI  - Muscarinic inhibition of the release of the adrenergic transmitter from
      peripheral sympathetic fibres.

PMID- 4351939
TI  - Importance of axonal transport of new amine granules for  3 H-noradrenaline
      retention capacity of adrenergic nerve terminals.

PMID- 4351941
TI  - Frequency response analysis of inotropic nerve action upon the isolated
      sympathetically innervated guinea-pig atrium.

PMID- 4351940
TI  - Morpho-physiological consideration on synaptic transmission in the amphibian
      sympathetic ganglion.

PMID- 4351942
TI  - A possible role of the catecholamine-containing neurons of the brain-stem of the
      cat in the sleep-waking cycle.

PMID- 4351943
TI  - Optimization aspects in biological control theory.

PMID- 4351944
TI  - A rapid electrophoretic technique for identification of subunit species of
      apoproteins in serum lipoproteins.

PMID- 4351945
TI  - Atomic absorption determination of zinc, copper, cadmium, and lead in tissues
      solubilized by aqueous tetramethylammonium hydroxide.

PMID- 4351946
TI  - Alternative methods of preparation and analysis of quasicrystalline protein from
      Neurospora crassa.

PMID- 4351947
TI  - Preparation of protohemin monomethyl ester.

PMID- 4351948
TI  - An improved cycling assay for nicotinamide adenine dinucleotide.

PMID- 4351949
TI  - A new electrophoretic-autoradiographic method for the visual detection of
      phosphotransferases.

PMID- 4351950
TI  - A note on the functional significance of phosphatases in the club cells of a
      fresh-water teleost, Saccobranchus fossilis.

PMID- 4351951
TI  - Inhibition of ACTH-induced differentiation of cortical cells and their
      mitochondria by corticosterone in tissue culture of fetal rat adrenals.

PMID- 4351952
TI  - Ablation therapy for hormone-dependent tumors.

PMID- 4351953
TI  - Chemical mediation of hormone action.

PMID- 4351955
TI  - Femoral neuropathy due to retroperitoneal bleeding. An unusual complication of
      heparin therapy.

PMID- 4351954
TI  - The reaction of products of sequential periodate oxidation of human erythrocyte
      glycoproteins with hemagglutinin from Helix pomatia.

PMID- 4351956
TI  - Articular chondrocalcinosis. Microanalysis of pyrophosphate (PPi) in synovial
      fluid and plasma.

PMID- 4351957
TI  - Experimental viral arthritis induced with herpes simplex.

PMID- 4351958
TI  - A review of arthropod-borne virus infections affecting man and animals in
      Australia.

PMID- 4351959
TI  - The utilization of zwitterionic buffer system in the plaque assay of a feline
      calicivirus.

PMID- 4351960
TI  - The recognition of viruses of the avian leucosis-sarcoma group and other viruses
      that interfere with Marek's disease research.

PMID- 4351961
TI  - [The immunosuppressive effect of cytostatics on delayed allergic reactions].

PMID- 4351962
TI  - [Cyclic 3',5'-adenosinemonophosphate (c-AMP)].

PMID- 4351964
TI  - [The synthesis of dihydroxy-25,26 cholecalciferol, a metabolite of vitamin D3].

PMID- 4351963
TI  - [Problems of oral smallpox vaccination].

PMID- 4351965
TI  - Analytical methods for mycotoxins.

PMID- 4351968
TI  - A radioimmunoassay for alpha 1 -foetoprotein.

PMID- 4351966
TI  - Lesions of renal glomeruli in mice with virus-induced diabetes mellitus-like
      disease.

PMID- 4351967
TI  - Biochemical and morphological investigations of 30 human insulinomas. Correlation
      between the tumour content of insulin and proinsulin-like components and the
      histological and ultrastructural appearance.

PMID- 4351969
TI  - Antigenic relationships among four herpesviruses.
AB  - Common viral antigens were detected, by fluorescent-antibody studies, in cells
      infected with herpes simplex virus 1, squirrel monkey herpesvirus 1, bovine
      rhinotracheitis, and equine abortion viruses. The two primate viruses showed
      slight cross-neutralization.

PMID- 4351970
TI  - Host defense mechanisms against Herpes simplex virus. I. Control of infection in
      vitro by senstized spleen cells and antibody.
AB  - Sensitized mouse spleen cells decrease the spread of herpes simplex virus
      infection in cell culture lines derived from human and murine tissues. These
      washed, sensitized cells act alone and additively in combination with antibody to
      diminish the ability of single virus-infected cells to spread infection to
      contiguous cells. This control of infection is not species specific, unlike
      interferon, and appears to be distinct from the effect of antibody. Lymphotoxin
      was not detected in this lymphocyte-mediated response. This control of herpes
      simplex virus infection in vitro by sensitized lymphoid cells is immunologically
      specific; spleen cells from donor animals immunized with a heterotypic virus do
      not cause herpesvirus plaque size reduction. The ratio of spleen cells from
      immunized animals to target monolayer cells needed to produce this effect is >
      4:1. Plaque size reduction of herpes simplex virus by spleen cells requires
      intact, immune, non-glass-adhering lymphoid cells.

PMID- 4351971
TI  - Isolation and characterization of an Avian adenovirus-associated virus.
AB  - An 18- to 20-nm virus particle was isolated from the Olson strain of quail
      bronchitis, an avian adenovirus. On density gradient separation the small virions
      were primarily found at densities of 1.39 and 1.42 g/cm(3). The majority of the
      infectious particles were at the heavier density. The virus had a hexagonal
      outline and contained single-stranded deoxyribonucleic acid. It was resistant to
      heating at 56 C for more than an hour and was not inactivated by treatment with
      chloroform or low pH. Purified virus did not agglutinate erythrocytes of various
      avian and mammalian species. Replication of the small particles occurred either
      in chicken embryos or in cultures of embryo kidney cells coinfected with an
      adenovirus helper. Antigenically the virus was distinct from the adeno-associated
      viruses types 1, 2, 3, and 4. The virus is the avian equivalent of the adeno
      associated viruses of primates and lower animals.

PMID- 4351972
TI  - Leukocytosis-promoting factor of Bordetella pertussis. II. Biological properties.
AB  - The leukocytosis-promoting factor (LPF), purified from materials extracted from
      agar in which Bordetella pertussis was grown, caused leukocytosis and an
      increased sensitivity to histamine when as little as 0.04 mug of protein was
      given intravenously to mice. LPF was adsorbed onto erythrocytes, causing
      hemagglutination. As little as 0.03 mug of LPF protein agglutinated chicken
      erythrocytes in 0.05 ml of a 0.5% suspension. The physicochemical, biological,
      and immunological properties indicated that leukocytosis, increased sensitivity
      to histamine in mice, and agglutination of erythrocytes are functions of a single
      substance.

PMID- 4351973
TI  - Antimetabolites of coenzyme Q. XV. Inhibition of mitochondrial reductase systems
      by naphthoquinone and quinolinequinone analogs.

PMID- 4351974
TI  - Cytomegalovirus infections during acute childhood leukemia.

PMID- 4351975
TI  - Isolation and comparison of bovine parvoviruses.

PMID- 4351976
TI  - Responses of gibbons to inoculation of Epstein-Barr virus.

PMID- 4351977
TI  - Dynamics of the splenic erythrocyte reservoir in the dog.

PMID- 4351978
TI  - The in vitro sensitivity of fish brain ATPases to organochlorine acaricides.

PMID- 4351979
TI  - Activation and inhibition of blood platelet adenylate cyclase by adenosine or by
      2-chloroadenosine.

PMID- 4351980
TI  - Diet in the prevention of heart disease.

PMID- 4351981
TI  - Rhinoviruses.

PMID- 4351982
TI  - [Influencing of side-effects of cytostatic drugs using metoclopramide].

PMID- 4351983
TI  - [Therapy of breast carcinoma in old age. Question 63,
      Munch.med.Wschr.114(1972)48,2122].

PMID- 4351984
TI  - Specificity of the control of protein synthesis by haemin.

PMID- 4351985
TI  - Comparison of free and 80S RNA-associated RNAs of mouse L cell virions.

PMID- 4351986
TI  - Influence of dibutyryl cyclicAMP and theophylline on cell surface antigens on
      oncornavirus transformed cells.

PMID- 4351987
TI  - Induction of steroidogenesis in tissue culture by cholera enterotoxin.

PMID- 4351988
TI  - Adrenergic receptors of the heart.

PMID- 4351989
TI  - Molecular mechanisms of hormone receptors.

PMID- 4351990
TI  - Isolation and characterization of hormone receptors.

PMID- 4351991
TI  - [Mitochondria].

PMID- 4351992
TI  - Reduced high affinity 5 -dihydrotestosterone receptor capacity in the ventral
      prostate of the aging rat.

PMID- 4351993
TI  - [Pathogenesis of the septic-toxic shock].

PMID- 4351994
TI  - [Angiochondrofibroma of the maxillary sinus].

PMID- 4351995
TI  - [Hormonal preparation of rheumatic fever and chronic tonsillitis patients,
      treated with corticosteroids, for tonsillectomy].

PMID- 4351996
TI  - Polydactyly in American negroes and whites.

PMID- 4351998
TI  - Crisis, conversion, and cult formation: an examination of a common psychosocial
      sequence.

PMID- 4351997
TI  - Follow-up of adolescents treated in a psychiatric hospital. I. A review of
      studies.

PMID- 4351999
TI  - Criterion approach to patient care evaluation.

PMID- 4352000
TI  - Urinary cyclic AMP in periodic catatonia.

PMID- 4352001
TI  - Collaborative provision of aftercare services.

PMID- 4352002
TI  - [The ultrastructure of the human corpus luteum. I. Evolution during the menstrual
      cycle].

PMID- 4352003
TI  - Role of the lung in angiotensin metabolism.

PMID- 4352004
TI  - Hormone producing tumors of the lung.

PMID- 4352005
TI  - Cytologic diagnosis of lung lesions by bronchial brushing.

PMID- 4352006
TI  - [Biochemical evolution of vitamin B1 deficiency. A comparative study of blood
      pyruvic acid and transketolase].

PMID- 4352007
TI  - Device for automatic rapid harvest of roller culture supernatant fluid.
AB  - A machine has been designed to remove and replace supernatant fluids
      automatically from roller culture bottles at frequent intervals.

PMID- 4352008
TI  - Evaluation of agar-gel double diffusion for the diagnosis of adenovirus
      infection.
AB  - Agar-gel double diffusion was compared to the Laboratory Branch complement
      fixation test. The efficacy of the agar-gel double diffusion test for the
      semiquantitation of group-specific adenovirus antibody and its usefulness as a
      serodiagnostic aid for the evaluation of adenovirus infection was determined.

PMID- 4352010
TI  - Intrawell absorption of antisera in a template thin-film gel diffusion method.
AB  - This report describes a method for in situ absorption of antisera within the
      template wells used in thin-film microgel diffusion. The intrawell absorption of
      antisera offers several advantages over previously reported techniques for
      detecting the presence of given antigens in biological preparations. The
      procedure is time saving, antigens are conserved, optimum antigen-antibody ratios
      are easily determined, and tests of several different absorbing antigens can be
      made on a single plate.

PMID- 4352009
TI  - Gentamicin blood agar used as a general-purpose selective medium.
AB  - The potential value of a blood agar medium containing a final concentration of
      5.5 mug of gentamicin per ml was assessed in a diagnostic laboratory over an 8
      week period. The medium gave increased isolation rates of beta-hemolytic
      streptococci, other streptococci, Bacteroides, clostridia, and yeasts. It also
      proved valuable in detecting gentamicin-resistant gram-negative bacilli when
      these were present in heavy mixed culture.

PMID- 4352011
TI  - Changes in the acetylcholine content in the rat brain after lesions of the
      septum, fimbria and hippocampus.

PMID- 4352012
TI  - Bilateral effects of the afferent impulses from the masseteric muscle on the
      trigeminal motoneuron of the cat.

PMID- 4352013
TI  - Some observations on the pathway of the vestibular rapid transmission system.

PMID- 4352014
TI  - Uptake of ( 14 C)glutamate into dorsal and ventral roots of spinal nerves of the
      rat.

PMID- 4352015
TI  - The effect of cyclic N-2-O-dibutyryl-adenosine-3',5'-monophosphate, adenosine
      triphosphate and butyrate on the body temperature of conscious cats.

PMID- 4352016
TI  - Origin and central pathways of crossed inhibitory effects of afferents from the
      masseteric muscle on the masseteric motoneuron of the cat.

PMID- 4352017
TI  - [Intracisternal 6-hydroxydopamine and sleep in the rat].

PMID- 4352018
TI  - Ectopic production of human chorionic gonadotropin in Ugandan patients with
      hepatocellular carcinoma.

PMID- 4352020
TI  - Dependence of human erythrocyte PRPP synthetase specific activity on
      concentration.

PMID- 4352019
TI  - Adriamycin--an antitumor antibiotic in the treatment of neoplastic diseases.

PMID- 4352021
TI  - Neurospora crassa pyruvate dehydrogenase: interconversion by phosphorylation and
      dephosphorylation.

PMID- 4352022
TI  - The interaction of yeast inorganic pyrophosphatase with bivalent cations and
      pyrophosphate.

PMID- 4352023
TI  - Inhibition of cyclic 3',5'-nucleotide phosphodiesterase in bovine taste papillae
      by bitter taste stimuli.

PMID- 4352024
TI  - In vitro synthesis rat serum lipoproteins and proteins by Morris hepatoma 7777.

PMID- 4352025
TI  - In vitro synthesis of rat serum lipoproteins and proteins by Morris hepatoma
      7777.

PMID- 4352026
TI  - Structure-activity studies of MSH-release-inhibiting hormone.

PMID- 4352027
TI  - Biosynthesis of mannan in Saccharomyces cerevisiae, isolation of a lipid
      intermediate and its identification as a mannosyl-1-phosphoryl polyrenol.

PMID- 4352028
TI  - Some observations on the cofactor requirement for partially purified DNA ligase
      from Escherichia coli.

PMID- 4352029
TI  - [Time-related changes in some effects of Bordeaux S and butter yellow in the
      rat].

PMID- 4352031
TI  - A histochemical study on some enzyme changes in the kidney, liver and brain after
      chronic mercury intoxication in the rat.

PMID- 4352030
TI  - Antioxidants and carcinogenesis: butylated hydroxytoluene, but not diphenyl-p
      phenylenediamine, inhibits cancer induction by N-2-fluorenylacetamide and by N
      hydroxy-N-2-fluorenylacetamide in rats.

PMID- 4352032
TI  - An improved sulphur assay applied to a problem of isethionate metabolism in squid
      axon and other nerves.

PMID- 4352033
TI  - Cyclic AMP and phosphodiesterase in synaptic vesicles from mouse brain.

PMID- 4352035
TI  - [Arterial hypertension associated with segmental compression of the renal artery
      by a chemodectoma: recovery after removal of the tumor and heminephrectomy].

PMID- 4352034
TI  - Effect of growth hormone on glycogenesis in cerebral cortical slices.

PMID- 4352036
TI  - Intracellular cyclic adenosine 3', 5'-monophosphate and relaxing effects of
      isoprenaline and papaverine on smooth muscle of intestine.

PMID- 4352037
TI  - Agarose-gel electrophoresis of soluble proteins from bronchial mucosa and
      bronchogenic carcinoma.

PMID- 4352038
TI  - Cells, intracells and schizogeny. 3. Formation of intracells in human amnion
      cells and SV40 virus-transformed mouse embryo cells cultured in vitro.

PMID- 4352039
TI  - Interferon induction by bluetongue virus and bluetongue virus ribonucleic acid.

PMID- 4352040
TI  - Clinical foot-and-mouth disease in the African buffalo (Syncerus caffer).

PMID- 4352041
TI  - Viruses and myocarditis.

PMID- 4352043
TI  - [Genetic analysis of skeletal diseases. Genetic report].

PMID- 4352042
TI  - Marijuana and ethanol: effects on sleep.

PMID- 4352044
TI  - [Treatment of peripheral facial paralysis and post-parotidectomy with ACTH-GEL.
      Report of 17 cases].

PMID- 4352045
TI  - [Significance of cytomegalovirus diseases in adult internal-medicine patients].

PMID- 4352046
TI  - [Lymphography of the retrosternal lymphatics].

PMID- 4352047
TI  - Endocrine studies during a 14-day continuous exposure to 5.2 per cent O 2  in N 2
      at pressure equivalent to 100 FSW (4 ATA).

PMID- 4352048
TI  - [Muscular glycogenosis. A biochemical study].

PMID- 4352049
TI  - Anaesthesia and toxicity of angiotensin and 5-hydroxytryptamine in rats.

PMID- 4352050
TI  - Rise in plasma angiotensin II and of blood pressure induced by 5
      hydroxytryptamine in rats.

PMID- 4352051
TI  - [Action of combinations of streptomycin with other antibiotics on intestinal
      bacilli in vitro].

PMID- 4352053
TI  - Cyclic AMP inhibition of reactions of glyceraldehyde 3-phosphate dehydrogenase.

PMID- 4352052
TI  - [Comparative study of the IR spectra of semisynthetic penicillins].

PMID- 4352054
TI  - Reaction of celite-bound fluorescein isothiocyanate with the 50S E. coli
      ribosomal subunit.

PMID- 4352055
TI  - Cuticlin: a noncollagen structural protein from Ascaris cuticle.

PMID- 4352056
TI  - Modification by bovine growth hormone of liver plasma membrane enzymes,
      phospholipids, and circular dichroism.

PMID- 4352057
TI  - Role of modifications in tyrosine transfer RNA. II. Ribothymidylate-deficient
      tRNA.

PMID- 4352058
TI  - Studies of the copper and heme cofactors of pseudomonad L-tryptophan-2,3
      dioxygenase by electron paramagnetic resonance spectroscopy.

PMID- 4352059
TI  - Studies on the properties of 1,N 6 -ethenoadenine derivatives of various
      coenzymes.

PMID- 4352061
TI  - Failure of actinomycin D to inhibit the induction of SV 40 viral antigen in BSC 1
      transformed cells.

PMID- 4352060
TI  - Virogenic properties of AKR mouse sarcoma cells induced by rous sarcoma virus.

PMID- 4352062
TI  - Physicochemical studies of equine infectious anemia virus. V. Effect of
      ultraviolet irradiation on virus infectivity.

PMID- 4352063
TI  - A new species of poliovirus top component.

PMID- 4352064
TI  - Avian sarcoma virus transformed hamster cells resistant to bromodeoxyuridine and
      deficient in thymidine kinase activity.

PMID- 4352065
TI  - Orthophosphate and amino acids as nutritional factors stimulating
      diethylaminoethyl-dextran-induced cell sensitization to transfection.

PMID- 4352066
TI  - Experiences from investigations of virus isolations from sewage over a two year
      period with special regard to polioviruses.

PMID- 4352067
TI  - Stimulation in vitro of prostatic ribonucleic acid polymerase by 5 
      dihydrotestosterone-receptor complexes.

PMID- 4352068
TI  - Lateral phase separations in binary mixtures of cholesterol and phospholipids.

PMID- 4352069
TI  - Phosphodiesterase activity and the potentiation by theophylline of
      adrenocorticotrophin stimulated steroidogenesis and adenosine 3',5'-monophosphate
      levels in isolated rat adrenal cells.

PMID- 4352071
TI  - Phosphorylcholine: a specific promoter of reparin and serum  -lipoprotein
      interaction.

PMID- 4352070
TI  - Activation of the template activity of isolated rat liver nuclei for DNA
      synthesis and its inhibition by NAD.

PMID- 4352072
TI  - A spin label study of E. coli membrane vesicles.

PMID- 4352073
TI  - The sequence and optical configuration of the amino acids xentoxin.

PMID- 4352074
TI  - Allosteric and isosteric modifiers of NADH binding to cytoplasmic malic
      dehydrogenase.

PMID- 4352076
TI  - Phospholipid hydrolysis by phospholipase A 1  and A 2  in plasma membranes and
      microsomes of rat liver.

PMID- 4352075
TI  - Electrostatic interactions in the binding of fluorescent probes to lipid
      membranes.

PMID- 4352078
TI  - Proteins and glycoproteins in plasma membrane fractions of avian leukosis-sarcoma
      virus susceptible and resistant chicken embryo fibroblasts.

PMID- 4352077
TI  - Isolation and properties of skeletal muscle plasma membrane.

PMID- 4352080
TI  - The use of a PMR probe for studying the hydrophobic properties of Micrococcus
      lysodeikticus membranes and membrane fractions.

PMID- 4352079
TI  - Structural properties of the membrane of intact human spermatozoa. A study with
      fluorescent probes.

PMID- 4352081
TI  - Ouabain binding sites and the (Na + ,K + )-ATPase of brain microsomal membranes.

PMID- 4352082
TI  - Heart rate variability during sleep and wakefulness in low-birthweight infants.

PMID- 4352084
TI  - Some pharmacological effects of the nematocide, morantel.
AB  - 1. In isolated nerve-muscle preparations as well as in nerve-muscle preparations
      in intact anaesthetized animals, morantel exhibited neuromuscular blocking
      properties similar to those of depolarizing blockers. The drug also caused
      spastic paralysis of 3 day-old chicks and contracture of the isolated toad rectus
      abdominis muscle.2. Morantel caused contraction of the guinea-pig and rabbit
      isolated small intestine. This effect was antagonized by atropine and
      hexamethonium.3. Morantel caused an increase in the blood pressure of the
      anaesthetized rat and cat and contraction of the nictitating membrane of the
      anaesthetized cat. These effects were antagonized by hexamethonium.4. It was
      concluded that morantel (like the related compound pyrantel) has acetylcholine
      like action and that its structure is consistent with such action.

PMID- 4352085
TI  - Effects of an isolated toxin from Australian tiger snake (Notechis scutatus
      scutatus) venom at the mammalian neuromuscular junction.
AB  - 1. The acute effects of a purified toxin from Australian Tiger snake (Notechis
      scutatus scutatus) venom have been investigated at the mammalian neuromuscular
      junction.2. The toxin was injected into the tail vein of mice. Death was due to
      respiratory paralysis.3. The resting membrane potential, and action potential of
      muscle fibres in muscles from in vivo intoxicated animals were normal.4. The
      frequency of miniature end plate potentials (m.e.p.p.s) from intoxicated nerve
      muscle preparations was reduced, although m.e.p.p. amplitude was unaltered.5.
      Nerve stimulation resulted in end plate potentials (e.p.p.s) of quantal
      amplitude; only rarely was the e.p.p. large enough to give rise to an action
      potential.6. High (20 mM) K(+) did not increase m.e.p.p. frequency in intoxicated
      preparations.7. The toxin was largely ineffective in vitro.8. The similarities
      and differences between this toxin, beta-bungarotoxin and botulinum toxin are
      discussed.

PMID- 4352083
TI  - The prejunctional actions of some non-depolarizing blocking drugs.
AB  - 1. Trains of end-plate potentials (e.p.p.s) have been recorded from the isolated
      tenuissimus of the cat. The muscle was paralyzed either by transversely cutting
      the muscle fibres or by non-depolarizing blocking drugs.2. The following
      parameters of transmitter synthesis, storage and release have been calculated:
      the quantal content of the first e.p.p. in the train, the size of the available
      store, fractional release, quantum size, and the rate of refilling of the
      available store.3. Tubocurarine and benzoquinonium depressed the rate of
      refilling of the available store causing its depletion at high rates of
      stimulation. This was offset by an increase in fractional release, which in the
      case of tubocurarine was sufficient for the quantal content of the first e.p.p.
      to be unchanged.4. Dimethyltubocurarine and pancuronium had a similar effect to
      tubocurarine on the rate of refilling of the store and depletion of the store at
      high rates of stimulation but did not increase fractional release. There was,
      therefore, a decrease in the quantal content of the first e.p.p.5. Lignocaine
      depressed the rate of refilling of the store and depleted the store at high rates
      of stimulation. Fractional release was also depressed.6. It is suggested that the
      non-depolarizing drugs have a weak local anaesthetic action retarding the influx
      of sodium into the nerve terminal which slows the rate of refilling of the store.
      This effect is due to the quaternary ammonium head. The presence of a phenolic
      group increases fractional release due either to an increased influx of calcium
      into the nerve terminal or to a potentiation of the actions of calcium.

PMID- 4352086
TI  - Pharmacological properties of centrally-administered agents which interfere with
      neurotransmitter function: a comparison with the central depressant effects of
      ouabain.
AB  - 1. Centrally administered sodium diethyldithiocarbamate (DDC) produced
      hypothermia, central nervous depression and potentiation of the antinociceptive
      effect of morphine. These effects resemble those seen with centrally administered
      ouabain. Furthermore, the interactions of (+)-amphetamine, desmethylimipramine
      and nialamide with DDC and ouabain were similar.2. 6-Hydroxydopamine by the same
      route also produced central nervous depressant effects including hypothermia,
      decreased locomotor activity and catalepsy but not ptosis.3. Both ouabain and
      chlorpromazine produced similar effects on behaviour and body temperature
      including selective abolition of a conditioned avoidance response.4. Although
      centrally administered tetrabenazine produced ptosis, decreased locomotor
      activity and catalepsy, it had no significant effect on body temperature.
      However, the hypothermia produced by peripherally administered reserpine was
      reversed by centrally administered dibutyryl cyclic 3',5'-adenosine
      monophosphate.5. Centrally administered cocaine and desmethylimipramine produced
      no depressant effects but an increased excitability and responsiveness were
      apparent in both cases.6. Although the observed behavioural depression and
      hypothermia can occur independently both seem to involve an interference with
      dopaminergic systems.

PMID- 4352087
TI  - Some effects of inhibiting endogenous prostaglandin formation on the responses of
      the cat spleen.
AB  - 1. Cat isolated spleens release prostaglandins into the venous effluent in
      response to stimuli such as nerve stimulation, noradrenaline and angiotensin
      II.2. The release of prostaglandins is abolished by pre-treatment of the spleen
      with indomethacin (0.3-5 mug/ml).3. The capsular and vascular responses to the
      different stimuli are augmented after inhibition of prostaglandin release.4. The
      prevention of prostaglandin release, as well as the augmentation of vascular and
      capsular responses, are reversible after indomethacin treatment is stopped.5. The
      role of prostaglandins as modulators of the responses to several stimuli is
      discussed.

PMID- 4352089
TI  - The surgical management of primary hepatocellular carcinoma in Uganda.

PMID- 4352088
TI  - Renin-like activity of the rat submaxillary gland: characterization and the
      effect of several drugs and stimuli.
AB  - 1. Renin-like activity was found in rat submaxillary glands.2. This activity was
      destroyed by boiling, was non-dialyzable and showed an optimum at approximately
      50 degrees C.3. Renin-like activity in the submaxillary gland was not diminished
      24 h after nephrectomy but was considerably reduced after ligature of the
      submaxillary duct.4. Renin-like activity in the submaxillary gland was reduced
      following food-deprivation, water-deprivation or hypovolemia.5. Renin-like
      activity in the rat submaxillary gland was increased after isoproterenol
      administration but not following pilocarpine.6. Renin-like activity in the rat
      submaxillary gland was increased considerably by administration of NaCl or KCl,
      as well as following adrenalectomy.7. Chlorothiazide and ouabain increased
      submaxillary renin-like activity but diazoxide did not affect this activity.

PMID- 4352090
TI  - Effects of exercise, training, and diet on muscle citric acid cycle enzyme
      activity.

PMID- 4352091
TI  - Activity and positional specificity of a rat plasma phospholipase on
      phosphatidylethanolamine.

PMID- 4352092
TI  - Dog kidney phospholipids and the question of renin inhibition.

PMID- 4352093
TI  - A spin-labelled fluorescent probe for membranes.

PMID- 4352094
TI  - Interrelationship between serum  -lipoprotein and cholinesterase.

PMID- 4352095
TI  - Chromatin low molecular weight RNA components.

PMID- 4352096
TI  - Translational control of protein synthesis in rat anterior pituitary by N 6 -2'-O
      dibutyryl adenosine 3',5'-monophosphate.

PMID- 4352097
TI  - Tumor and plasma ACTH concentrations in patients with and without the ectopic
      ACTH syndrome.

PMID- 4352098
TI  - ACTH secretion by bronchial carcinoid tumours.

PMID- 4352099
TI  - Steroid 17,20-desmolase deficiency: a new cause of male pseudohermaphroditism.

PMID- 4352100
TI  - [Effects of beta 1-24 ACTH and cycloheximide on the steroid production. The
      mechanism of the cation of so-called "regulator protein"].

PMID- 4352101
TI  - [Experimental studies on the mechanism of ACTH secretion following acute
      stimulation].

PMID- 4352102
TI  - [Organ culture of the parathyroid gland].

PMID- 4352103
TI  - Herpes simplex encephalitis: a light and electron microscopic study in a fatal
      case.

PMID- 4352104
TI  - Forefoot reconstruction. A case study.

PMID- 4352106
TI  - Stress relaxation in rat skin after treatment with hormones.

PMID- 4352105
TI  - Autogenous immunity to endogenous RNA tumor virus. Radioimmune precipitation
      assay of mouse serum antibody levels.
AB  - The radioimmune precipitation assay using (3)H-labeled AKR leukemia virus was
      applied to the detection and quantitation of natural serum antibodies directed
      against endogenous murine leukemia virus (MuLV) envelope antigens B6C3F(1) and
      BALB/c mice, which have low natural incidences of leukemia and lymphoma, and AKR
      mice, which have a high incidence, were used in this study. Sera from mice of
      various age groups were assayed. A marked difference in age-associated levels of
      the autogenous immune response to endogenous murine leukemia virus was detected,
      and the quantitative differences among these strains were inversely related to
      the incidence of lymphoma. The radioimmune precipitation test as applied was 500
      times more sensitive than virus neutralization. That the reactions we have
      observed are specific is suggested by several lines of evidence, including the
      nonreactivity of normal hamster and absorbed rat serum, the positive reaction of
      absorbed rat anti-AKR serum, the inhibition of precipitation of labeled virus by
      purified unlabeled virus, and isopycnic gradient analysis of the reactive
      products.

PMID- 4352107
TI  - Influence of chronic neostigmine treatment on the number of acetylcholine
      receptors and the release of acetylcholine from the rat diaphragm.
AB  - 1. Rats were treated twice daily for 7 days with neostigmine and the diaphragm
      was isolated for study of its acetylcholine content, release upon nerve
      stimulation and the number of receptors in the end-plate.2. While the content of
      total acetylcholine was unchanged, the release of acetylcholine on stimulation
      with trains of 500 pulses at 100 Hz every 20 sec was reduced by about 50%. Five
      days after the end of neostigmine treatment the release of acetylcholine
      recovered to normal.3. The total number of acetylcholine receptors in the end
      plate as measured from the binding of N, O-di[(3)H]acetyl alpha-bungarotoxin was
      reduced from 2.1 x 10(7) to 1.2 x 10(7) per end-plate.4. The above-mentioned
      changes are not due to acute pharmacological effects of neostigmine, nor to an
      immediate effect of cholinesterase inhibition but presumably due to chronic
      accumulation of acetylcholine at the neuromuscular junction.

PMID- 4352108
TI  - Effects of proteolytic enzymes on function and structure of frog neuromuscular
      junctions.
AB  - 1. Frog cutaneous pectoris nerve-muscle preparations were incubated with
      collagenase and protease and examined with electrophysiological and electron
      microscopic techniques.2. The physiological properties and intracellular
      ultrastructural appearance of individual muscle and nerve cells were not affected
      by the enzyme treatment. However, neuromuscular transmission and the morphology
      of the nerve-muscle junction were altered.3. Collagenase produced an irreversible
      loss of activity of end-plate cholinesterase and a partial loss of stainable
      ;synaptic cleft material'.4. Protease produced these changes and, in addition,
      the entire basement membrane was digested, which led to ;synaptic disjunction' of
      nerve terminals and muscle end-plates.

PMID- 4352109
TI  - Descending and segmental inhibition of transmission through the spinocervical
      tract.
AB  - 1. Micro-electrode recordings were made from axons of the spinocervical tract in
      unanaesthetized decerebrate-spinal cats.2. The effects of stimulation of (1)
      descending systems at the level of the upper cervical spinal cord and (2) hind
      limb cutaneous nerves, on discharges of spinocervical tract neurones were
      examined.3. Effects were obtained from bilateral spinal cord regions in the
      dorsolateral funiculi and the most medial and ventral parts of the ventral
      funiculi and also from the dorsal columns in the upper cervical region even
      though the columns had been transected at low thoracic and upper lumbar levels.4.
      Stimulation of either descending or segmental systems inhibited spontaneous and
      evoked responses. Facilitation was not seen. The inhibition had a time course of
      up to 250 msec, with maximal action at 20-40 msec and was greatest for
      polysynaptic responses or those evoked from the smaller myelinated cutaneous
      axons.5. It is suggested that the descending and segmental systems converge on to
      common inhibitory interneurones.

PMID- 4352110
TI  - Carcinogenesis in tissue culture. 21. Changes in back-transplantability of the
      population of rat ascites hepatoma JTC-15 cells during a long-term of
      cultivation.

PMID- 4352111
TI  - Nasopharyngeal carcinoma and Epstein-Barr virus. I. Factors related to the anti
      VCA antibody.

PMID- 4352113
TI  - Clostridium perfringens exotoxins. I. Purification and properties of  -toxin.

PMID- 4352112
TI  - Nasopharyngeal carcinoma and Epstein-Barr virus. II. Clinical course and the anti
      VCA antibody.

PMID- 4352115
TI  - [Wilm's tumor of large dimensions in a 4-year-old child].

PMID- 4352114
TI  - [The compensatory character of peripheral vessel reactions under conditions of
      tonic vascular wall tension].

PMID- 4352116
TI  - [Treatment of peripheral nerve injuries].

PMID- 4352117
TI  - [Pipe smoking less dangerous than cigarettes?].

PMID- 4352118
TI  - [Alimentary toxinfection caused by Clostridium perfringens].

PMID- 4352120
TI  - Mode of action of hallucinogenic molecules.

PMID- 4352119
TI  - Adenyl cyclase of polymorphonuclear leukocytes.

PMID- 4352121
TI  - Assignment of codons to arginine residues in vertebrate proteins.

PMID- 4352122
TI  - Influence of cyclization and acyl substitution on the inotropic effects of
      adenine nucleotides.

PMID- 4352123
TI  - Effects of flow-stop on the metabolism of noradrenaline released by nerve
      stimulation in the perfused spleen.

PMID- 4352124
TI  - Alterations produced by cortisol in the spontaneous activity and responsiveness
      to sensory stimuli of single cells in the tuberal hypothalamus of the rat.

PMID- 4352125
TI  - Studies on the in vitro and the in vivo transcription of the bluetongue virus
      genome.

PMID- 4352126
TI  - Visualization of the extracapsid coat in certain bluetongue-type viruses.

PMID- 4352127
TI  - Phagocytic activity of peritoneal exudate cells from mice.

PMID- 4352128
TI  - Therapeutic planning for patients with lung cancer.

PMID- 4352129
TI  - Lung biopsy: transbronchoscopic, percutaneous, open.

PMID- 4352130
TI  - Mediastinal tumors and cysts in the pediatric patient.

PMID- 4352131
TI  - Alveolar and tissue phospholipids of rat lung.

PMID- 4352132
TI  - Effects of changes in sodium balance and of experimental renal hypertension on
      plasma angiotensin I converting enzyme activity of rabbits.

PMID- 4352134
TI  - Treatment of adenovirus type 8 kerato-conjunctivitis.

PMID- 4352133
TI  - The disinfection of instruments and hands during outbreaks of epidemic
      keratoconjunctivitis.

PMID- 4352135
TI  - Pseudomalignant cutaneous amoebiasis in Uganda.

PMID- 4352136
TI  - [Organization of the receptor fields of the forebrain cortical neurons in the
      tortoise, Emysorbicularis].

PMID- 4352137
TI  - Riboflavin carrier protein from egg yolk. Spectral and other properties observed
      upon binding of flavin to apoprotein.

PMID- 4352138
TI  - [Interference-microscopy dry-mass studies on the nucleus, plasma and nucleolus of
      diploid mouse embryonal cells infected with adenovirus type 5].

PMID- 4352139
TI  - The effects of nitrofuranfuradroxyl on the phosphatase enzymes in kidney and
      liver of rats.

PMID- 4352141
TI  - Probable explanation for differential inhibition of hepatoma growth in liver upon
      carbohydrate deprivation.

PMID- 4352140
TI  - Complex conformations in mitochondrial DNA isolated from rat ascites hepatoma
      cells.

PMID- 4352142
TI  - Studies on urinary infections in diabetics. IV. Significant bacteriuria in
      pregnancy in relation to age of onset, duration of diabetes, angiopathy and
      urological symptoms.

PMID- 4352144
TI  - Studies on arterial and renal venous plasma renin activity in hypertensive
      patients.

PMID- 4352145
TI  - Lipoprotein lipase activity of human adipose tissue in health and in some
      diseases with hyperlipidemia as a common feature.

PMID- 4352146
TI  - Cell size and lipolysis by human subcutaneous adipose tissue.

PMID- 4352148
TI  - A philosophy of relaxation. Eleventh annual Baxter-Travenol lecture.

PMID- 4352147
TI  - Primary epithelial neoplasms of the lacrimal sac.

PMID- 4352149
TI  - Do maternally administered neuromuscular blocking agents interfere with fetal
      neuromuscular transmission?

PMID- 4352150
TI  - The effect of renal failure and hyperkalemia on the duration of pancuronium
      neuromuscular blockade in man.

PMID- 4352152
TI  - A new short-acting antagonist of angiotensin II.

PMID- 4352151
TI  - Parenteral long-acting corticosteroids: effect on hypothalamic-pituitary-adrenal
      function.

PMID- 4352153
TI  - Mechanism of acetylcholine release by drugs and its blockade.

PMID- 4352154
TI  - Influence of vasoactive hormones on mammary arterial blood flow in lactating
      cows.

PMID- 4352156
TI  - Interaction of lipids with acid-soluble bovine skin collagen.

PMID- 4352155
TI  - Effect of sulfur compounds on various sulfhydryl-dependent enzyme systems.

PMID- 4352157
TI  - Neonatal diseases in dogs and cats.

PMID- 4352159
TI  - Chronic benign familial pemphigus. Induction of lesions by Herpesvirus hominis.

PMID- 4352158
TI  - Analysis of human hypoxanthine-guanine phosphoribosyl transferase isozymes by
      isoelectric focusing in polyacrylamide gel.

PMID- 4352160
TI  - Pulmonary cavitary lesion with productive cough.

PMID- 4352161
TI  - Cervical chemodectoma with extensive pulmonary metastases.

PMID- 4352162
TI  - Delayed granuloma following bronchography.

PMID- 4352163
TI  - Wilms tumor: diagnosis by thoracentesis.

PMID- 4352164
TI  - Mediastinal xanthoma with familial hyperlipoproteinemia.

PMID- 4352165
TI  - Clinical staging of primary lung cancer.

PMID- 4352166
TI  - The spectrum of diffuse pulmonary infiltration in malignant disease.

PMID- 4352167
TI  - Clinical significance of hemodynamic findings in hypertension.

PMID- 4352168
TI  - ACTH and calcitonin secreting medullary carcinoma of the thyroid.

PMID- 4352169
TI  - The effect of chlorpromazine on pituitary function.

PMID- 4352170
TI  - Hydrolytic enzymes of the hepatopancreas of the ascidian, Pyura stolonifera.

PMID- 4352171
TI  - A radioimmunoassay for MTV-antigens.

PMID- 4352172
TI  - Carcinoma associated with fistula in ano.

PMID- 4352173
TI  - Gas gangrene of the anterior abdominal wall.

PMID- 4352174
TI  - Histidyl-transfer ribonucleic acid synthetase mutants requiring a high internal
      pool of histidine for growth.
AB  - Mutants that require histidine due to an altered structural gene for the histidyl
      transfer ribonucleic acid synthetase (hisS) have been isolated by a general
      selection for histidine-requiring strains in which the mutation producing
      histidine auxotrophy is unlinked to the histidine operon. One of the mutants has
      been shown to require an abnormally high internal histidine pool for growth owing
      to an altered synthetase that is unstable at low histidine concentrations. It is
      difficult to determine accurately the K(m) for histidine of the synthetase enzyme
      from the mutant because of the instability of the enzyme at limiting histidine
      concentrations; however, a histidine K(m) value has been estimated that is
      approximately 100 times higher than the histidine K(m) of the wild-type enzyme.
      For the mutant strains to achieve the high internal pool of histidine required
      for growth, all the systems that transport histidine from the growth medium must
      be functioning to capacity. Amino acids that interfere with histidine transport
      strongly inhibit the growth of the mutants. The mutants have been useful in
      providing a selective genetic marker for transductional mapping in the hisS
      region. The mutants are discussed as representative of a general class of curable
      mutants that have an altered enzyme with poor affinity for a substrate or
      coenzyme.

PMID- 4352175
TI  - Common enzymes of branched-chain amino acid catabolism in Pseudomonas putida.
AB  - Two types of Pseudomonas putida PpG2 mutants which were unable to degrade
      branched-chain amino acids were isolated after mutagenesis and selection for
      ability to grow on succinate, but not valine, as a sole source of carbon. These
      isolates were characterized by growth on the three branched-chain amino acids
      (valine, isoleucine, and leucine), on the corresponding branched-chain keto acids
      (2-ketoisovalerate, 2-keto-3-methylvalerate, and 2-ketoisocaproate), and on other
      selected intermediates as carbon sources, and by their enzymatic composition. One
      group of mutants lost 2-ketoisovalerate-inducible branched-chain keto acid
      dehydrogenase that was active on all three keto acids. There was also a
      concomitant loss of ability to grow on all three branched-chain amino acids as
      well as on all three corresponding keto acids, but there was retention of ability
      to use subsequent intermediates in the catabolism of branched-chain amino acids.
      Another type of mutant showed a marked reduction in branched-chain amino acid
      transaminase activity and grew poorly at the expense of all three amino acids,
      but it utilized subsequent intermediates as carbon sources. Both the transaminase
      and branched-chain keto acid dehydrogenase mutants retained the ability to
      degrade camphor. These findings are consistent with the view that branched-chain
      amino acid transaminase and branched-chain keto acid dehydrogenase are common
      enzymes in the catabolism of valine, isoleucine, and leucine.

PMID- 4352176
TI  - Genetic and biochemical investigation of the Escherichia coli mutant hfl-1 which
      is lysogenized at high frequency by bacteriophage lambda.
AB  - The Escherichia coli mutant hfl-1 is lysogenized at very high frequency by
      bacteriophage lambda. The normal requirement for the lambdacIII gene product in
      the establishment of repression is not observed in hfl-1 strains. These
      phenotypic characteristics are specified by a single locus at 82.5 min on the E.
      coli map in extremely close proximity to the purA gene, cotransduction
      frequencies ranging from 97 to 100% depending on the particular purA marker used.
      The lactose operon is shown to function normally in this strain, and there are
      also no demonstrable differences in ribonucleic acid polymerase activity or
      cyclic-adenosine monophosphate levels. Alterations in the cell envelope are
      indicated by a slight rifamycin resistance, which is reversible by pretreating
      the cells with ethylenediaminetetraacetic acid, and by a resistance to penicillin
      and a sensitivity to high concentrations of sodium dodecyl sulfate. It is not
      known whether this change in cell surface is the primary lesion, or a pleiotropic
      effect of some more basic metabolic shift.

PMID- 4352177
TI  - Metabolism of the pyridine nucleotides involved in nicotinamide adenine
      dinucleotide biosynthesis by Clostridium butylicum.
AB  - In order to elucidate the mechanism of the accumulation of considerable amounts
      of free nicotinic acid (NA) in the culture medium of Clostridium butylicum, this
      organism was investigated with regard to its ability to metabolize nicotinamide
      adenine dinucleotide (NAD) and its immediate biosynthetic precursors, nicotinic
      acid mononucleotide (NAMN) and nicotinic acid adenine dinucleotide (deamido-NAD).
      Cell-free extracts of C. butylicum were found to degrade NAMN and deamido-NAD to
      NA. NAMN, in the presence of adenosine triphosphate (ATP), was converted to
      deamido-NAD, but only at high concentrations of ATP (20 mM) was significant
      synthetic activity observed in competition with NAMN degradation. Degradation of
      both NAMN and deamido-NAD was activated by ATP at concentrations of 5 and 10 mm.
      Anaerobiosis markedly enhanced the degradation of the nucleotides. The data
      indicate that the synthesis of NAMN and deamido-NAD prevails over their
      degradation only in the presence of high concentrations of ATP. NAD was degraded
      to nicotinamide mononucleotide (NMN) by a pyrophosphatase. Phosphate markedly
      inhibited both the deamido-NAD and NAD pyrophosphatases. Under anaerobic
      conditions there was practically no further degradation of NMN to NA, whereas
      barely measurable amounts of NA were formed under aerobic conditions. All of
      these observations suggest that, under the given conditions of anaerobiosis and
      physiological phosphate concentrations, there is very little degradation of NAD
      to NMN and practically no degradation to NA by C. butylicum. Thus, NAD represents
      an insignificant source of the NA accumulated in the culture medium. The
      intermediates in the biosynthetic pathway (NAMN and deamido-NAD) have been shown
      to be the major source of the NA which is accumulated by C. butylicum.

PMID- 4352178
TI  - Relationship of adenosine 3',5'-monophosphate to growth and metabolism of
      Tetrahymena pyriformis.
AB  - The concentration of adenosine 3',5'-monophosphate (cyclic AMP) and the activity
      of adenylate cyclase were determined for the first time in conjuncation with
      cyclic 3',5'-nucleotide phosphodiesterase (phosphodiesterase) during the growth
      cycle of Tetrahymena pyriformis. High levels of cyclic AMP observed during early
      exponential and late stationary phases were associated with elevated adenylate
      cyclase and decreased phosphodiesterase activities. Adenylate cyclase and cyclic
      AMP were decreased and phosphodiesterase was increased in cells grown in glucose
      supplemented medium. In contrast to findings in mammalian liver, cyclic AMP was
      decreased during active gluconeogenesis in Tetrahymena. This suggests a different
      modulation of carbohydrate metabolism in the two species. The results illustrate
      that both the content of cyclic AMP and its action as a regulatory agent in
      Tetrahymena are uniquely suited to the metabolism of this organism.

PMID- 4352179
TI  - Respiratory development in Saccharomyces cerevisiae grown at controlled oxygen
      tension.
AB  - Saccharomyces cerevisiae was grown in batch culture over a wide range of oxygen
      concentrations, varying from the anaerobic condition to a maximal dissolved
      oxygen concentration of 3.5 muM. The development of cells was assayed by
      measuring amounts of the aerobic cytochromes aa(3), b, c, and c(1), the cellular
      content of unsaturated fatty acids and ergosterol, and the activity of
      respiratory enzyme complexes. The half-maximal levels of membrane-bound
      cytochromes aa(3), b, and c(1), were reached in cells grown in O(2)
      concentrations around 0.1 muM; this was similar to the oxygen concentration
      required for half-maximal levels of unsaturated fatty acid and sterol. However,
      the synthesis of ubiquinone and cytochrome c and the increase in fumarase
      activity were essentially linear functions of the dissolved oxygen concentration
      up to 3.5 muM oxygen. The synthesis of the succinate dehydrogenase, succinate
      cytochrome c reductase, and cytochrome c oxidase complexes showed different
      responses to changes in O(2) concentration in the growth medium. Cyanide
      insensitive respiration and P(450) cytochrome content were maximal at 0.25 muM
      oxygen and declined in both more anaerobic and aerobic conditions. Cytochrome c
      peroxidase and catalase activities in cell-free homogenates were high in all but
      the most strictly anaerobic cells.

PMID- 4352182
TI  - An iron-containing superoxide dismutase from Escherichia coli.

PMID- 4352183
TI  - Fractionation of the C-apoproteins from human plasma very low density
      lipoproteins.

PMID- 4352181
TI  - Inhibition by fluoride ion of hormonal activation of fat cell adenylate cyclase.

PMID- 4352184
TI  - Effects of ethanol and fat on the transport of reducing equivalents into rat
      liver mitochondria.

PMID- 4352180
TI  - Structure-function unitization model of biological membranes.

PMID- 4352186
TI  - Studies on the role of ribosomal proteins L 7  and L 12  in the in vitro
      synthesis of  -galactosidase.

PMID- 4352185
TI  - Comparative biological chemistry of cobalt hemoglobin.

PMID- 4352187
TI  - Glucocorticoid receptors in lung. II. Specific binding of glucocorticoids to
      nuclear components of rabbit fetal lung.

PMID- 4352188
TI  - Properties of the luteinizing hormone receptor of isolated bovine corpus luteum
      plasma membranes.

PMID- 4352189
TI  - Preparation and characterization of plasma membranes from bovine corpus luteum.

PMID- 4352190
TI  - The plasma membrane of isolated fat cells. I. Identification of trypsin-sensitive
      membrane peptides by sodium dodecyl sulfate polyacrylamide gel electrophoresis.

PMID- 4352191
TI  - Perifused fat cells. Effect of lipolytic agents.

PMID- 4352193
TI  - Function of phosphorylated ribosomes. The activity of ribosomal subunits
      phosphorylated in vitro by protein kinase.

PMID- 4352192
TI  - The distribution of carbohydrate groups in rat skin collagen.

PMID- 4352194
TI  - The dynamic equilibrium of folding and unfolding of nuclease-T.

PMID- 4352195
TI  - Positional specificities of acyl coenzyme A: glycerophosphate and acyl coenzyme
      A: monoacylglycerophosphate acyltransferases in Escherichia coli.

PMID- 4352196
TI  - Glucagon stimulation of adenylate cyclase sulfhydryl reactivity. Evidence for
      hormone-induced conformational changes.

PMID- 4352197
TI  - The valence and spin state of iron in oxyhemoglobin as inferred from resonance
      Raman spectroscopy.

PMID- 4352198
TI  - Modification of the rat's startle reaction by termination of antecedent acoustic
      signals.

PMID- 4352199
TI  - Localization of phosphatase activity on the membranes of the mammalian sperm
      head.

PMID- 4352200
TI  - Neuraminidase "unmasking" and failure of trypsin to "unmask"  -D-galactose-like
      sites on erythrocyte, lymphoma, and normal and virus-transformed fibroblast cell
      membranes.

PMID- 4352201
TI  - Anaerobic glycolysis in spontaneous and transplanted liver tumors of mice.

PMID- 4352202
TI  - Distinctive cells similar to fetal hepatocytes associated with liver
      carcinogenesis by diethylnitrosamine. Electron microscopic study.

PMID- 4352204
TI  - Types B and C RNA virus in breast tissue and milk of wild mice.

PMID- 4352205
TI  - Infection of embryonic myogenic cells with murine sarcoma virus in vitro.

PMID- 4352203
TI  - Unusually high incidence of spontaneous lymphomas in wild house mice.

PMID- 4352206
TI  - Immunologic studies of pertussis. Development of precipitins.

PMID- 4352207
TI  - Acceleration of growth and bone maturation in childhood thyrotoxicosis.

PMID- 4352208
TI  - Insulin secretion in children with constitutional familial short stature.

PMID- 4352210
TI  - Central modulation of baroreceptor reflex by angiotensin.

PMID- 4352209
TI  - Intravenous alimentation in patients with cancer and neutropenia.

PMID- 4352211
TI  - Complications of influenza and their management.

PMID- 4352212
TI  - Sexual differences in the hypothalamic cholinergic system before and after
      puberty: inductory effect of testosterone.

PMID- 4352213
TI  - The relationship between maternal and neonatal sleep.

PMID- 4352214
TI  - Serum total lipids and lipid fractions in marasmus.

PMID- 4352215
TI  - Abnormalities of carbohydrate and lipid metabolism in experimentally induced
      acute uremia.

PMID- 4352216
TI  - Open-field behavior, habituation and passive avoidance learning: effect of ACTH
      and hydrocortisone on normal and adrenalectomized rats.

PMID- 4352217
TI  - A mutant transcription factor that is activated by 3':5'-cyclic guanosine
      monophosphate.
AB  - We report here the isolation of an extragenic suppressor of a promoter mutation
      in the lactose operon of Escherichia coli. Genetic data have indicated that the
      suppressor of the P(-) mutation maps in the structural gene for the transcription
      factor catabolite activator protein. Biochemical studies suggest that the mutant
      molecules of catabolite activator protein are altered in such a way that they are
      activated by 3':5'-cyclic GMP in addition to their normal effector, 3':5'-cyclic
      AMP.

PMID- 4352218
TI  - Interaction of amines with ketone aldehydes and unsaturated aldehydes.
AB  - The optical changes occurring during the interaction of amines with ketone
      aldehydes or unsaturated aldehydes are accompanied by strong electron spin
      resonance signals, and can thus be explained as due to the transfer of one whole
      electron in the ground state.

PMID- 4352219
TI  - Nonvirion antigens produced by herpes simplex viruses 1 and 2.
AB  - Of nine herpes simplex virus 1 strains (from lip, mouth, throat, cornea, or
      brain) only five produced enough nonvirion antigen (i.e., not a structural
      component of the virus) to be detected by complement fixation with specially
      prepared, virion-absorbed, type-1 guinea pig antisera, while the remaining four
      strains produced only enough of the same antigen to induce specific antibody in
      hyperimmunized guinea pigs. While the type 1 virion antiserum used reacted
      equally well by complement fixation with the type 1 and type 2 strains, the type
      1 nonvirion antisera failed to react with nonvirion antigens produced by three
      type-2 (genital) strains. However, type 2 nonvirion antiserum reacted equally
      well with the three type 2 and four type 1 nonvirion antigens that were tested.
      It appears, therefore, that while herpes simplex virus 1 codes only for type 1
      nonvirion antigen, herpes simplex 2 codes not only for an immunologically
      distinct type 2 nonvirion antigen but also for enough type 1 nonvirion antigen to
      stimulate antibody production for it. Herpes simplex 2 nonvirion antigen
      exhibited the same properties as type 1, i.e., its activity was lost on storage
      at 4 degrees for 15 days, it was sedimented by centrifugation at 33,360 x g for 1
      hr, and the maximum concentration was found at 3 hr in guinea pig kidney culture
      cells, but at 24 hr in HEp 2 and rabbit kidney culture cells. Sera from patients
      with genital lesions caused by herpes simplex virus 2, as well as from randomly
      selected adults, failed to react with either type 2 or type 1 nonvirion antigens.
      Accordingly, the basic information is now available to permit the use of these
      nonvirion antigens to determine the possible role of the herpes simplex viruses
      in certain human cancers.

PMID- 4352220
TI  - Purification of mouse interferon by affinity chromatography on a solid-phase
      immunoadsorbent.
AB  - A solid-phase immunoadsorbent capable of binding mouse interferon has been
      prepared. Starting from crude tissue-culture material, interferon could be
      purified 1990 times in a single step of affinity chromatography. Overall recovery
      ranged from 55 to 103% with tissue culture and mouse-brain interferon; however,
      only 5% was obtained with Sendai virus-induced interferon from mouse serum.

PMID- 4352221
TI  - Evidence for the absence of the G-T-psi-C sequence from two mammalian initiator
      transfer RNAs.
AB  - Analyses were performed on the purified initiator tRNA from rabbit liver to test
      for the presence of Psip and Tp in this molecule. Neither of these nucleotides
      could be detected after hydrolysis by piperidine, NaOH, or T2 RNase. Similarly
      digestion with venom phosphodiesterase plus phosphatase failed to release any
      pseudourdine or ribothymidine. Identical results were obtained with the initiator
      tRNA from sheep mammary gland. The absence of these nucleosides was confirmed by
      pancreatic and T1 RNase digestion of the rabbit-liver initiator tRNA. The
      classical G-T-Psi-C sequence was not detected in this molecule. An A-U-C-G
      sequence has been identified; it may possibly replace the G-T-Psi-C sequence.

PMID- 4352223
TI  - Effects of adrenal glucocorticoids on polyoma virus replication.
AB  - Treatment of polyoma virus-infected fibroblasts from mouse embryos and virus
      infected 3T3 cells with physiological concentrations of the glucocorticoids
      enhances plaque formation at least 10-fold. The data suggest that this effect
      results from an increased rate of virus production. Steroid specificity studies
      indicate that the cytoplasmic receptors that mediate the physiological actions of
      these hormones are also involved in the present effect.

PMID- 4352222
TI  - Transformation of chick-embryo fibroblasts by wild-type and temperature-sensitive
      Rous sarcoma virus alters adenylate cyclase activity.
AB  - The activity of the enzyme adenylate cyclase, a component of the plasma membrane,
      has been determined in chick-embryo fibroblasts and in cells transformed by
      either Bryan high-titer strain of Rous sarcoma virus (RSV-BH) or a temperature
      sensitive mutant of this virus (RSV-BH-Ta). Adenylate cyclase activity is reduced
      in cells transformed by the wild-type virus and also by the temperature-sensitive
      mutant when the cells are grown at the permissive temperature (37 degrees ).
      Transformation results in an altered affinity (K(m)) for the substrate (Mg ATP).
      The apparent K(m) ATP is 0.23 mM in normal cells and 1.1 mM in cells transformed
      with wild-type virus. The K(m) ATP of the cells infected with RSV-BH-Ta is 0.67
      1.0 mM at 37 degrees and 0.28 mM at 42 degrees . The enzyme from normal cells
      appears to have two binding sites for Mg(++), one at the catalytic site and a
      second at a regulatory site. Transformation by RSV-BH or RSV-BH-Ta (37 degrees )
      apparently alters this second Mg(++) site. A decrease in adenylate cyclase
      activity occurs within 10 min after cells infected with RSV-BH-Ta are shifted
      from 42 degrees to 37 degrees ; the activity falls to one-half that of normal
      cells 30 min after the temperature shift. Our observations indicate that a viral
      function lowers cyclic AMP content by lowering the activity of adenylate cyclase,
      probably through some modification of the plasma membrane.

PMID- 4352224
TI  - Activation of prolyl hydroxylase in L-929 fibroblasts by ascorbic acid.
AB  - The addition of ascorbate to the culture medium of early log-phase mouse
      fibroblasts (L-929 cells) resulted in a 5-fold increase of prolyl hydroxylase
      activity. Maximal activity was reached within 2 hr after addition of 5 muM
      ascorbate. The total amount of enzyme-related antigen did not change on treatment
      with ascorbate and the activation was shown to be independent of RNA and protein
      synthesis. The increase in activity caused by ascorbate is therefore due to the
      activation of a preformed precursor. Enzyme (molecular weight 260,000-300,000)
      and putative precursor (molecular weight 85,000-105,000) were separated by
      chromatography on DEAE-Sephadex. Treatment of intact cells with dithiothreitol
      resulted in an almost quantitative conversion of the enzyme to the smaller
      inactive protein. When these cells were treated with ascorbate or incubated
      overnight in fresh medium the enzyme reappeared and precursor concentrations
      decreased proportionately. Ascorbate may act by bringing about aggregation of
      enzymatically inactive subunits.

PMID- 4352225
TI  - Amino-acid acceptor activity of the "70S-associated" 4S RNA from avian
      myeloblastosis virus.
AB  - The "70S-associated" 4S RNA from avian myeloblastosis virus contains transfer
      RNA, as determined by aminoacylation. The various amino acids esterified, plus
      the great number of minor bases found in this "70S-associated" 4S RNA indicate
      that a sizeable fraction, but not all, of this RNA is transfer RNA.

PMID- 4352227
TI  - A physiological mechanism for Hebb's postulate of learning.
AB  - Hebb's postulate of learning envisages that activation or inactivation of extant
      synaptic contacts in plastic neural networks depends on the synchronous impulse
      activity of pre- and postsynaptic nerve cells. The physiological mechanism
      proposed here for this process posits that at synapses acting according to Hebb's
      postulate, the receptors for the neurotransmitter are eliminated from the
      postsynaptic membrane by the transient reversals of the sign of membrane
      polarization that occur during action potential impulses in the postsynaptic
      cell. But, since the release of neurotransmitter drives the membrane potential of
      the synaptic zone towards a level about half-way between the negative-inside
      resting potential and the positive-inside action potential, it would follow that
      the membrane patches surrounding the receptors of a synapse whose activity has
      contributed to setting off the postsynaptic impulse would be spared the full
      extent of the noxious polarity reversal. This mechanism can account for a
      neurophysiologically documented example of the operation of Hebb's postulate,
      namely the plasticity of the connections between fourth- and fifth-order neurons
      in the visual cortex of cats.

PMID- 4352226
TI  - Continuous propagation of radiation leukemia virus on a C57BL mouse-embryo
      fibroblast line, with attenuation of leukemogenic activity.
AB  - The radiation leukemia virus (RadLV), a murine leukemia virus derived from thymic
      lymphomas induced by x-irradiation in strain C57BL/Ka mice, has been successfully
      propagated in sustained high titer in vitro in a newly established line, BL-5, of
      C57BL/Ka mouse-embryo fibroblasts. In addition, the production of endogenous
      virus, presumed to be RadLV, has been induced and sustained through multiple
      serial passages after treatment of BL-5 cell cultures with 5-bromodeoxyuridine.
      The chronically RadLV-infected subline, designated BL-5 (RadLV), sheds virus into
      the supernatant culture fluids that is biologically active in vitro in the XC
      cell plaque assay, in interference assays for focus-formation by murine sarcoma
      virus, and in the intracellular induction of group-specific antigens detectable
      by immunofluorescence, but is apparently devoid of leukemogenic activity after
      intrathymic inoculation into neonatal or immunosuppressed C57BL/Ka mice. Although
      BL-5 cells exhibited morphological alterations suggestive of transformation in
      vitro and gave rise to fibrosarcomatous ascites tumors after intraperitoneal
      inoculation with C57BL/Ka mice, the chronically infected BL-5(RadLV) cells
      remained normal in morphology and failed to yield fibrosarcomas in vivo.

PMID- 4352228
TI  - Pituitary-adrenal responsiveness in surgical patients on acute and chronic
      corticosteroid therapy: plasma corticosterone assay.

PMID- 4352229
TI  - On the fine structure of horse sweat glands.

PMID- 4352230
TI  - The effect of aminophylline on pentagastrin-induced gastric secretion in the dog.

PMID- 4352231
TI  - Sequential immunization procedure against Group B arboviruses using living
      attenuated 17D yellow fever virus, living attenuated Langat E5 virus, and living
      attenuated dengue 2 virus (New Guinea C isolate).

PMID- 4352232
TI  - Passive immunity for arbovirus infection. II. Quantitative aspects of naturally
      and artificially acquired protection in mice for Japanese (B) encephalitis virus.

PMID- 4352233
TI  - Axillary metastases from unknown primary sites.

PMID- 4352235
TI  - Crystalloid inclusions in the Schwann cell cytoplasm.

PMID- 4352236
TI  - Evidence that endogenous cyclic AMP does not modulate serum sulfation factor
      action on embryonic chicken cartilage.

PMID- 4352234
TI  - The evaluation of a new peritoneoscope as a diagnostic aid to the surgeon.

PMID- 4352237
TI  - Induction of serine dehydratase activity by cyclic AMP is restricted to S phase
      in synchronized CHO cells.

PMID- 4352238
TI  - Amino acid compositions of simian virus 40 structural proteins.

PMID- 4352239
TI  - Inhibition of Escherichia coli growth by cyclic adenosine 3', 5'-monophosphate.

PMID- 4352241
TI  - Adenylate cyclase activity is decreased in chick embryo fibroblasts transformed
      by wild type and temperature sensitive Schmidt-Ruppin Rous sarcoma virus.

PMID- 4352240
TI  - Association of prolyl hydroxylase activity with membranes.

PMID- 4352242
TI  - Occurrence of cis-7-tetradecenoic acid in the envelope phospholipids of
      Escherichia coli K12.

PMID- 4352244
TI  - The inhibition of the avian myeloblastosis virus DNA polymerase by poly(U)
      fractions of varying chain length.

PMID- 4352243
TI  - Polyriboadenylate synthesizing activity in chromatin of wheat seedlings.

PMID- 4352245
TI  - Identification and extent of fluid bilayer regions in membranous cytochrome
      oxidase.

PMID- 4352246
TI  - A rapid method for the isolation of rat liver plasma membranes using an aqueous
      two-phase polymer system.

PMID- 4352247
TI  - Localization of an RNA-degrading system of enzymes on the rat liver plasma
      membrane.

PMID- 4352249
TI  - [Electric interaction of parallel non-myelinated nerve fibers. IV. Role of
      anatomic non-uniformities of the nerve trunks].

PMID- 4352248
TI  - [Secondary free-radical reactions in irradiated frozen aqueous solutions of amino
      acids and peptides].

PMID- 4352250
TI  - [Light-induced EPR signals in the photoreduction and photo-oxidation of
      chlorophyll and its analogs].

PMID- 4352251
TI  - Space-time clustering of limb defects in Cardiff.

PMID- 4352252
TI  - Infectious mononucleosis.

PMID- 4352253
TI  - Settlement of Mr. Kenneth Robinson's libel action.

PMID- 4352254
TI  - Cell-mediated immunity to Varicella-Zoster antigen in acute Herpes zoster
      (shingles).

PMID- 4352256
TI  - Magnetic-circular-dichroism studies of cytochrome c and cytochrome b 2 .

PMID- 4352255
TI  - Immunoconglutinin response in patients with acute viral respiratory disease.

PMID- 4352257
TI  - Oxidation of acetaldehyde by rat-liver mitochondria in relation to ethanol
      oxidation and the transport of reducing equivalents across the mitochondrial
      membrane.

PMID- 4352258
TI  - Molecular weight and subunit structure of the malate-lactate transhydrogenase.

PMID- 4352259
TI  - Studies on metabolism of lung flukes of the genus Paragonimus. VI. Succinoxidase
      system in homogenates of eggs, larvae, and adults.

PMID- 4352261
TI  - Limb-girdle muscular dystrophy. Case report with electron microscopic study of a
      muscle biopsy.

PMID- 4352260
TI  - Plasma renin studies in patients with traumatic spinal cord injuries.

PMID- 4352263
TI  - The detection of Clostridium welchii in the differential reinforced clostridial
      medium technique.

PMID- 4352262
TI  - Growth and development of children with Legg-Calve-Perthes syndrome in Israel.

PMID- 4352264
TI  - [Morphologic studies on the action of ethidium bromide on in vitro cultured
      Pleurodeles waltlii embryonic cells].

PMID- 4352265
TI  - Nitroblue tetrazolium reduction by neutrophils: biochemical and ultrastructural
      effects of methylene blue.

PMID- 4352266
TI  - Studies on the mechanism of inflammation induced by calcium pyrophosphate
      crystals.

PMID- 4352267
TI  - Dose-response to lead ingestion in rats fed low dietary calcium.

PMID- 4352269
TI  - [Primary septic cholecystitis due to Clostridium perfringens. A case report].

PMID- 4352268
TI  - Intrathecal gentamicin in treatment of bacterial meningitis.

PMID- 4352270
TI  - Twenty-four hour patterns of plasma luteinizing hormone and follicle-stimulating
      hormone in sexual precocity.

PMID- 4352271
TI  - Clinical dermatology (third of three parts).

PMID- 4352272
TI  - Case records of the Massachusetts General Hospital. Weekly clinicopathological
      exercises. Case 32-1973.

PMID- 4352273
TI  - [Figure painting as a cerebral function test].

PMID- 4352274
TI  - [Role of cyclic AMP in the mechanical activity of smooth muscle].

PMID- 4352277
TI  - [Articular cartilage. 1. Physiology in the adult].

PMID- 4352276
TI  - [Gestagens and uterine neoplasms].

PMID- 4352275
TI  - [Colpocytogram abnormalities during anemia due to folic acid deficiency].

PMID- 4352278
TI  - [Disseminated intravascular coagulation (D.I.V.C.) after lipiodol
      splenotomography].

PMID- 4352279
TI  - [Receptors of steroid hormones].

PMID- 4352280
TI  - [Cytochrome oxidase, structure and function].

PMID- 4352281
TI  - [Genuine and false primary tumors of the thoracic wall (apropos of 24 cases)].

PMID- 4352282
TI  - [Attempt at prolonged stimulation of adrenocortical insufficiency by long-acting
      beta-1-24-corticotrophin].

PMID- 4352283
TI  - Lead inclusion bodies in osteoclasts.
AB  - Inclusion bodies occur frequently in the nuclei and rarely in the cytoplasm of
      osteoclasts in pigs with experimental lead poisoning. The light and electron
      microscope pictures of undemineralized sections are similar to those described
      for liver cord cells and renal tubular cells.

PMID- 4352284
TI  - The prolactin cell of the white-crowned sparrow, Zonotrichia leucophrys
      pugetensis.

PMID- 4352285
TI  - Ultrastructure of the aesthetase hairs of the littoral decapod, Paragrapsus
      gaimardii.

PMID- 4352286
TI  - The fine structure of the lutein cells in the mink (Mustela vison) with special
      reference to the secretory activity during pregnancy.

PMID- 4352287
TI  - The ultrastructural arrangement of thrombosthenin in glycerol extracted
      thrombocytes.

PMID- 4352288
TI  - Progressive external ophthalmoplegia--some clinical associations.

PMID- 4352290
TI  - Degeneration activity in the rat urinary bladder.

PMID- 4352289
TI  - An attempt to explain nervous transmitter release as due to nerve impulse-induced
      cation exchange.

PMID- 4352291
TI  - Afferent discharges via the laryngeal communicans related to respiration in the
      rat.

PMID- 4352292
TI  - High-pressure anion exchange chromatography and enzymatic isotope displacement
      assays for cyclic AMP and cyclic GMP.

PMID- 4352293
TI  - Determination of relative levels of cyclic AMP in tissues or cells prelabeled
      with radioactive adenine.

PMID- 4352294
TI  - Saturation assay for cyclic AMP using endogenous binding protein.

PMID- 4352295
TI  - An assay method for cyclic AMP and cyclic GMP based upon their abilities to
      activate cyclic AMP-dependent and cyclic GMP-dependent protein kinases.

PMID- 4352296
TI  - Radioimmunoassay for the measurement of cyclic nucleotides.

PMID- 4352297
TI  - Analysis of cyclic AMP and cyclic GMP by enzymic cycling procedures.

PMID- 4352298
TI  - The luminescence assay of cyclic AMP.

PMID- 4352300
TI  - Protein binding assays for cyclic nucleotides.

PMID- 4352299
TI  - Firefly luminescence in the assay of cyclic AMP.

PMID- 4352301
TI  - Herpesvirus type 2 in genitourinary tract infections.

PMID- 4352302
TI  - Effects of sonication on physicochemical and biological properties of synthetic
      double-stranded polyribonucleotides as interferon inducer.

PMID- 4352303
TI  - Inhibitory effect of N-phenyl-N'-aryl or alkylthiourea derivatives on the
      multiplication of some picornaviruses (Coxsackie B 1, ECHO 19, and foot-and-mouth
      disease virus) in cell cultures.

PMID- 4352304
TI  - [The use of CrCl 3  for coupling of foot-and-mouth disease virus to erythrocytes,
      and the ability of these sensitized erythrocytes to react in passive
      hemagglutination (PHA) and passive immunohemolysis (PIH)].

PMID- 4352305
TI  - Infection of chick embryo tracheal organ cultures with influenza A2 (Hong Kong)
      virus. II. Electron microscopy.

PMID- 4352306
TI  - The use of frozen cells in the agar-cell suspension titration technique. A
      reproducible system. Brief report.

PMID- 4352307
TI  - Bovine virus diarrhoea virus: acquired resistance to acriflavine. Brief report.

PMID- 4352308
TI  - The ultrastructure of acute silicosis.

PMID- 4352310
TI  - Multifocal granular cell myoblastoma. Report of a case involving trachea,
      stomach, and anterior abdominal wall.

PMID- 4352309
TI  - Morphological effects of Compound 48-80, polymyxin B sulfate, and dextran on rat
      skeletal muscle.

PMID- 4352312
TI  - The use of tetanic and single twitch stimuli to assess neuromuscular block in
      man.

PMID- 4352311
TI  - Possible role of cyclic AMP in gastric acid secretion in rat. Activation of
      carbonic anhydrase.

PMID- 4352313
TI  - The effects of oestrogen, ACTH and cortisone administration and hypophysectomy on
      histological changes induced by unilateral renal pedicle clamping.

PMID- 4352314
TI  - Immunological assessment of mice with chronic jaundice and runting induced by
      reovirus 3.

PMID- 4352316
TI  - Oestrogen receptor in human breast cancer tissue and response to endocrine
      therapy.
AB  - Oestrogen receptor determinations were done in metastatic breast cancer tissue of
      patients with advanced breast cancer. In 37 patients with progressive disease
      evaluation of the response to endocrine treatment was possible, following the
      criteria of the E.O.R.T.C. Co-operative Breast Cancer Group. In 20 patients with
      receptor-negative tumours two objective remissions were noted; in 17 patients
      with receptor-positive tumours 14 objective remissions were seen. There seems to
      be a striking correlation between the presence or absence of oestrogen receptor
      in tumour tissue and the clinical response to hormonal therapy.

PMID- 4352315
TI  - Significance of high plasma renin activity in patients on maintenance
      haemodialysis therapy.
AB  - Blood pressure and plasma renin activity were remeasured after an interval of 8
      to 17 months in 16 patients on maintenance haemodialysis previously found to have
      high renin activity. Continuing intermittent haemodialysis changed the plasma
      renin activity and blood pressure but no consistent pattern was seen. This
      confirmed our previous finding that adequate dialysis can control blood pressure
      in the presence of high renin activity. We therefore conclude that bilateral
      nephrectomy should be approached with renewed caution.

PMID- 4352318
TI  - [On Paget's disease].

PMID- 4352317
TI  - The vanishing chronic. The reduction of the resident patient population of a
      large urban Ontario mental hospital from 1950 to 1970 with an analysis of
      associated administrative and therapeutic changes.

PMID- 4352319
TI  - Radioimmunoassay for plasma renin activity.

PMID- 4352320
TI  - A sensitive bioassay for adrenocorticotrophic hormone in human plasma.

PMID- 4352321
TI  - Urinary pregnanediol and pregnanetriol in the salt-losing and nonsalt-losing
      forms of C-21-hydroxylase deficiency.

PMID- 4352322
TI  - Cystosarcoma phyllodes.

PMID- 4352323
TI  - Effect of 1-naphthyl isothiocyanate and 3-methylcholanthrene on
      hepatocarcinogenesis in rats treated with diethylnitrosoamine.

PMID- 4352324
TI  - Relations between postnatal days of mice and carcinogenic effect of cycasin.

PMID- 4352325
TI  - Influence of vascular permeability on blood-borne metastasis.

PMID- 4352326
TI  - Inhibitory effect of a streptococcal preparation (OK-432) on the nucleic acid
      synthesis in tumor cells in vitro.

PMID- 4352327
TI  - Virus-like particles observed in transplantable intrahepatic bile duct carcinomas
      and hepatoma of Syrian golden hamsters.

PMID- 4352328
TI  - Carcinoma of the large intestine of rats induced by rectal infusion of
      methylazoxymethanol.

PMID- 4352330
TI  - A new method for the investigation of the kinetics of the capture reaction in
      phosphatase cytochemistry. I. Theoretical aspects of the local formation of
      crystalline precipitates.

PMID- 4352329
TI  - What a dietitian should know about hyperlipidemia.

PMID- 4352331
TI  - A new method for the investigation of the kinetics of the capture reaction in
      phosphatase cytochemistry. II. Theoretical and experimental study of phosphate
      diffusion from thin polyacrylamide films.

PMID- 4352332
TI  - Neutralizing activity in human sera against the leukocyte-transforming agent.

PMID- 4352333
TI  - Angiotensin II analogs. 10. Stereochemical factors in the 5 position influencing
      pressor activity.

PMID- 4352334
TI  - 6-Substituted 5-chloro-1,3-dihydro-2H-imidazo(4,5-b)pyrazin-2-ones with
      hypotensive activity.

PMID- 4352335
TI  - [Motor functions and control of sensory messages of somatic origin].

PMID- 4352336
TI  - [Immunologic exploration of cancer patients. 1. Nontumoral immunity].

PMID- 4352337
TI  - Antibiotics and the kidney.

PMID- 4352339
TI  - Electroneuroprostheses: past and present uses in man.

PMID- 4352340
TI  - Ceramics, glasses, and composites in medicine.

PMID- 4352341
TI  - Further study on acute hemorrhagic cystitis due to adenovirus type 11.

PMID- 4352342
TI  - Viral cystitis.

PMID- 4352344
TI  - Stomach contractions at REM sleep in goats and sheep.

PMID- 4352343
TI  - Transplantability of avian lymphoid tumor cells.

PMID- 4352345
TI  - Acetylcholine-dependent molecular receptor. Activation of triphosphoinositide
      phosphomonoesterase.

PMID- 4352346
TI  - Oral tumours in Kenya.

PMID- 4352347
TI  - Normal structure, ultrastructure and enzyme content of glomic cells.

PMID- 4352348
TI  - Roentgen and telecobalt therapy of tumors of the brain.

PMID- 4352349
TI  - [Electromyographic characteristics of motor disorders in tumors of the posterior
      portions of the cerbral hemispheres].

PMID- 4352350
TI  - Cerebral hemodynamics in carotid surgery.

PMID- 4352351
TI  - Is there a vestibulo-spinal reflex contribution to running?

PMID- 4352353
TI  - Experimental cerebellar uvulonodular lesions in the squirrel monkey.

PMID- 4352352
TI  - The vestibular thalamus in the rhesus monkey.

PMID- 4352354
TI  - Galvanic body sway in normals and patients with 8th nerve lesions.

PMID- 4352356
TI  - [Paget's disease of the breasts].

PMID- 4352355
TI  - Studies on methanol-oxidizing bacteria. I. Isolation and growth studies.

PMID- 4352357
TI  - [Ultrastructural organ specificity of the cells of human cancerous tumors].

PMID- 4352358
TI  - [Histochemistry of the placental enzymes normally and in antenatal fetal death].

PMID- 4352359
TI  - [Congenital tumors of the newborn: fibrosarcoma of the soft tissues of the upper
      extremities and adenoma of the adrenal cortex].

PMID- 4352360
TI  - Long-acting phenothiazines in the prevention of relapse of schizophrenic
      patients.

PMID- 4352361
TI  - Potentiation of rifampicin, rifampicin analogs, and tetracycline against animal
      cells by amphotericin B and polymyxin B.

PMID- 4352362
TI  - A comparative study of some properties of chromatin from two "minimal deviation"
      hepatomas.

PMID- 4352363
TI  - DNA polymerases I and II in regenerating rat liver and Morris hepatomas.

PMID- 4352364
TI  - Viropexis of type B particles in reticulum cell sarcoma of R3-Dm strain mice.

PMID- 4352365
TI  - Vincristine treatment of advanced cancer: a cooperative study of 392 cases.

PMID- 4352366
TI  - Separable DNA polymerase activities in host liver and Morris hepatomas.

PMID- 4352367
TI  - Poly(adenosine diphosphate ribose) synthesis during the cell cycle of transformed
      hamster lung cells.

PMID- 4352369
TI  - Rapid arrest of DNA synthesis by N 6 ,O 2' -dibutyryl cyclic adenosine 3',5'
      monophosphate in cultured hepatoma cells.

PMID- 4352368
TI  - Protein turnover in microsomal subfractions of liver and Morris hepatomas 7800
      and 9618A.

PMID- 4352370
TI  - Protection against radiation leukemogenesis by repeated injections of immune and
      nonimmune foreign sera.

PMID- 4352371
TI  - A comparison review of key epidemiological studies in cervical cancer related to
      current searches for transmissible agents.

PMID- 4352372
TI  - A selective review of experimental studies in cervical carcinoma.

PMID- 4352373
TI  - Latent infections induced by herpes simplex viruses.

PMID- 4352374
TI  - The transcription and state of herpes simplex virus DNA in productive infection
      and in human cervical cancer tissue.

PMID- 4352375
TI  - Summary of informal discussion on general aspects of herpesviruses.

PMID- 4352376
TI  - Evidence for an oncogenic potential of the Epstein-Barr virus.

PMID- 4352377
TI  - Simian herpesviruses.

PMID- 4352378
TI  - Oncogenicity of rabbit herpesvirus.

PMID- 4352380
TI  - Summary of informal discussion on oncogenicity of other herpesviruses.

PMID- 4352379
TI  - Oncogenic potential of guinea pig herpes- and C-type viruses.

PMID- 4352381
TI  - Clinical features of herpes genitalis.

PMID- 4352382
TI  - Relation of cytohistopathology of genital herpesvirus infection to cervical
      anaplasia.

PMID- 4352383
TI  - Summary of informal discussion of part I of genital herpesvirus.

PMID- 4352384
TI  - A review of the identification and titration of antibodies to herpes simplex
      viruses type 1 and type 2 in human sera.

PMID- 4352385
TI  - An analysis of seroepidemiological studies of herpesvirus type 2 and carcinoma of
      the cervix.

PMID- 4352386
TI  - Possible etiologies of cancer of the cervix other than herpesvirus.

PMID- 4352387
TI  - Prospective studies of the association of genital herpes simplex infection and
      cervical anaplasia.

PMID- 4352388
TI  - Effect of herpesvirus type 2 and hormonal imbalance on the uterine cervix of the
      mouse.

PMID- 4352389
TI  - Herpesvirus and cervical cancer studies in experimental animals.

PMID- 4352390
TI  - Summary of informal discussion of part 3 of genital herpesvirus and of in vivo
      animal studies.

PMID- 4352391
TI  - Transformation of hamster embryo fibroblasts by herpes simplex viruses type 1 and
      type 2.

PMID- 4352392
TI  - Human embryonic lung cells transformed by herpes simplex virus.

PMID- 4352393
TI  - Virions and antigens of herpes virus type 2 in cervical carcinoma.

PMID- 4352394
TI  - Nucleic acid hybridization and the relationship between cervical cancer and
      herpes simplex virus type 2.

PMID- 4352396
TI  - Symposium on herpesvirus and cervical cancer. Epilog.

PMID- 4352395
TI  - Summary of informal discussion of experimental approaches.

PMID- 4352397
TI  - Summary of papers delivered at the Conference on Herpesvirus and Cervical Cancer
      (Key Biscayne, Florida).

PMID- 4352398
TI  - Epithelial cell surfaces and the basement membrane in the ocular lens, studied
      with the scanning electron microscope.

PMID- 4352399
TI  - Cataracts induced by the polypeptide antibiotic polymyxin B sulfate.

PMID- 4352400
TI  - [Dependence of magnesium-activated inosine phosphatase activity of the actomyosin
      on the ionic strength].

PMID- 4352401
TI  - Effect of some drugs on the chemotaxis of rabbit neutrophils in vitro.

PMID- 4352402
TI  - Immunohistochemical demonstration of glucagon in an A 2 -cell carcinoma.

PMID- 4352403
TI  - Distribution of vitamin D 3 : evidence of accumulation in renal proximal tubuli
      and thyroid parafollicular cells.

PMID- 4352404
TI  - Effects of hypophysectomy on lactate metabolism in the perfused rat liver.

PMID- 4352405
TI  - 4-Uloses as intermediates in enzyme-nicotinamide adenine dinucleotide-mediated
      oxidoreductase mechanisms. I. Uridine diphosphate-galactose-4-epimerase.

PMID- 4352406
TI  - 4-Uloses as intermediates in enzyme-nicotinamide adenine dinucleotide-mediated
      oxidoreductase mechanisms. II. Regulation of enzymatic activity by reductive
      inhibition.

PMID- 4352407
TI  - Further studies of the interaction of cyclic adenosine 3':5'-monophosphate with
      endometrial protein kinase.

PMID- 4352408
TI  - The pH dependence of the steady state kinetic parameters for staphylococcal
      nuclease-catalyzed hydrolysis of deoxythymidine-3'-phosphate-5'-p
      nitrophenylphosphate in H 2  O and D 2  O.

PMID- 4352409
TI  - The vasopressin-sensitive adenylate cyclase of the rat renal medulla.

PMID- 4352410
TI  - Studies on the kinetic mechanism of lipoamide dehydrogenase from rat liver
      mitochondria.

PMID- 4352411
TI  - Assembly of the vesicular stomatitis virus envelope: incorporation of viral
      polypeptides into the host plasma membrane.

PMID- 4352414
TI  - Bone cell response to calcium active drugs.

PMID- 4352413
TI  - Variable response of renin activity in primary and secondary hypertension.

PMID- 4352415
TI  - The influence of psychiatry in medical education.

PMID- 4352412
TI  - Transmural gradient of NAD-NADPH ratio in their canine left ventricular
      myocardium, and effects of coronary dilators on the transmural gradient.

PMID- 4352416
TI  - Methal-induced granulomatous hypersensitivity in man.

PMID- 4352417
TI  - Streptozotocin-induced lactic acidosis. A case report and some experimental
      observations.

PMID- 4352418
TI  - A low-temperature EPR study of partially purified, soluble ferric cytochromes P
      450 and P-448 from rat liver microsomes.

PMID- 4352419
TI  - Thermal transitions of proteins.

PMID- 4352420
TI  - The use of gel chromatography to study rapid equilibria of the type A + B forms
      and is formed from C + D.

PMID- 4352421
TI  - Effects of preparation method on reversible conformational changes induced by
      neutral salts in spin-labeled erythrocyte membranes.

PMID- 4352422
TI  - Proton relaxation rate and fluorometric studies of manganese and rare earth
      binding to concanavalin A.

PMID- 4352423
TI  - A comparison of kinetic parameters obtained with three major non-interconvertible
      isozymes of rat pyruvate kinase.

PMID- 4352424
TI  - Observations on the ultrastructure of the buccal epithelium of the rat.

PMID- 4352425
TI  - Ultrastructure of rat odontoblasts in various stages of their development and
      maturation.

PMID- 4352426
TI  - Partial purification and properties of rat liver mitochondrial polynucleotide
      phosphorylase.
AB  - 1. Polynucleotide phosphorylase was partially purified from the inner membrane of
      rat liver mitochondria. 2. The partially purified particulate enzyme catalyses
      phosphorolysis of poly(A), poly(C), poly(U) and RNA to nucleoside diphosphates.
      3. It is devoid of nucleoside diphosphate-polymerization activity. 4. Variable
      amounts of ADP/P(i)-exchange activity are associated with the polynucleotide
      phosphorylase and are probably due to a different enzyme. 5. ADP is the preferred
      substrate for exchange, and little or no reaction occurs with other nucleoside
      diphosphates, but ATP/P(i)-exchange takes place at one-third the rate observed
      with ADP. 6. The partially purified enzyme is free from the phosphatases found in
      the crude mitochondrial inner membrane, but is associated with an endonuclease
      activity and some adenylate kinase activity; no cytidylate kinase activity
      analogous to the latter was detectable.

PMID- 4352427
TI  - Induction of bacterial enzymes.

PMID- 4352428
TI  - Mechanism of action of cortisol in rat liver.

PMID- 4352430
TI  - Nitrogenase of Klebsiella pneumoniae: electron-paramagnetic-resonance studies on
      the catalytic mechanism.

PMID- 4352429
TI  - Preparation and some properties of a suspension of fragmented tubules from rat
      kidney.
AB  - A method is described whereby short fragments of rat kidney tubule were obtained
      when kidney slices were gently dispersed by exposure to collagenase and
      hyaluronidase. When suspended in buffered saline the fragmented tubules respired
      actively over a period of several hours, the rate of oxygen consumption being
      proportional to the amount of cell protein. Oxygen uptake was stimulated by the
      addition of glucose, lactate, butyrate, alpha-oxoglutarate and other substrates
      and was decreased by the omission of Ca(2+) from the suspending medium. With
      alpha-oxoglutarate as the added substrate, dinitrophenol strongly stimulated
      oxygen uptake. Dinitrophenol had a less-marked stimulatory effect when glucose
      was the added substrate, and inhibited respiration in the absence of added
      substrate. Oligomycin inhibited respiration and this inhibition was partially
      reversed by dinitrophenol. Fragmented tubules synthesized glucose from lactate at
      a high rate but this capacity for gluconeogenesis was abolished by dinitrophenol
      and by physically damaging the cells.

PMID- 4352432
TI  - The induction of ornithine decarboxylase in cultured hepatoma cells.

PMID- 4352431
TI  - Regulation of L-serine dehydratase in developing rat liver.

PMID- 4352433
TI  - Creatine kinase activity in cultures of differentiating myoblasts.

PMID- 4352434
TI  - The effect of calcium on temperature-induced phase changes in liquid-crystalline
      cardiolipin structure.

PMID- 4352436
TI  - B-cell amplification by dibutyryl cyclic AMP in mice.

PMID- 4352435
TI  - Membrane reconstitution in chl-r mutants of Escherichia coli K 12. V. ATPase
      incorporation into particles formed by complementation.

PMID- 4352437
TI  - Basic concepts underlying recent developments in the field of Parkinson's
      disease.

PMID- 4352438
TI  - [A new and simplified method for the detection of LP-X, a cholestasis specific
      lipoprotein].

PMID- 4352439
TI  - [Certainty and suspicions of herpetic encephalitis. Electroencephalographic
      aspects].

PMID- 4352440
TI  - The relationship of rapidly labeled adrenal RNA synthesis to steroidogenesis in a
      superfusion system: effect of ACTH.

PMID- 4352441
TI  - Endogenous gonadotropin requirements for follicular growth and maintenance in
      immature rats pretreated with PMS.

PMID- 4352442
TI  - Acute effects of altered photoperiods on the onset of ovulation in gonadotropin
      treated immature rats.

PMID- 4352443
TI  - Inhibition of adrenocorticotropic hormone production by glucocorticoids in mouse
      pituitary tumor cells.

PMID- 4352444
TI  - The effect of phenformin on lipolysis and the concentration of cyclic AMP and ATP
      in white fat cells.

PMID- 4352445
TI  - Adrenal cells in tissue culture. X. On the mechanism of the stimulation of
      steroidogenesis by cyclic cytidine monophosphate.

PMID- 4352446
TI  - Interaction of glucagon and catecholamines in the regulation of serine
      dehydratase.

PMID- 4352447
TI  - Effects of p-chlorophenoxyisobutyrate (CPIB) on serum insulin levels, insulin
      sensitivity, and adipose tissue cyclic AMP concentration.

PMID- 4352448
TI  - Control of insulin secretion by catecholamines, stress, and the sympathetic
      nervous system.

PMID- 4352449
TI  - Insulin receptor of liver and fat cell membranes.

PMID- 4352450
TI  - The problem of identifying the glucagon receptor.

PMID- 4352452
TI  - Control of free radical mechanisms in nucleic acid systems: studies in
      radioprotection and radiosensitization.

PMID- 4352451
TI  - Lipid peroxidation damage to cell components.

PMID- 4352453
TI  - Falcon Herpesvirus, the etiologic agent of inclusion body disease of falcons.
AB  - A viral agent has been isolated from five fatal cases of naturally occurring
      inclusion body disease in three different falcon species, namely, the prairie
      falcon (Falco mexicanus), the red-headed falcon (F. chiquera), and the peregrine
      falcon (F. peregrinus). The virus has been shown to possess the physical,
      chemical, and biological properties of a herpesvirus and has been used to
      reproduce inclusion body disease in the prairie falcon, merlin (F. columbarius),
      and American kestrel (F. sparverius). A similar disease was also produced with
      this virus in the great horned owl (Bubo virginianus), screech owl (Otus asio),
      and ring-necked turtle dove (Streptopelia risoria). Serological comparison of the
      falcon herpesvirus with other known avian herpesviruses revealed that the virus
      is antigenically closely related to a pigeon herpesvirus and an owl herpesvirus
      while differing from the former in host range. No antigenic relationship to
      infectious laryngotracheitis virus, duck virus enteritis, or Marek's disease
      virus could be demonstrated.

PMID- 4352454
TI  - Hemagglutination-inhibition test in rhinovirus infections of volunteers.
AB  - The hemagglutination-inhibition (HI) test for antirhinovirus antibody was carried
      out on paired sera from volunteers inoculated with rhinovirus type 3 or type 4
      (RV4). The HI test gave results which paralleled the neutralization test and was
      at least as sensitive as a microneutralization method for detection of serotype
      specific antibody. Although high levels of HI antibody in the serum were
      associated with protection from infection, in the case of RV4 low serum HI
      antibody levels did not necessarily imply susceptibility to challenge with small
      doses of virus. HI activity could be measured in concentrated nasal-washing
      fluids, and this antibody also seemed relevant to protection against infection.

PMID- 4352455
TI  - Surface antigens produced by Herpesviruses Varicella-Zoster virus.
AB  - Surface antigen(s) was demonstrated by the mixed agglutination technique on cell
      cultures infected with varicella-zoster virus (V-Z). The reactions appeared to be
      specific for V-Z, and no cross-reaction was obtained with herpes simplex virus
      (HSV). V-Z surface antigen had similar physicochemical properties to that of HSV.
      It was stable to heating at 56 C and treatment with 1% Formalin, 2,4
      dinitrophenol, and periodate, whereas it was undetectable after exposure to
      acetone or ethanol. Antibodies detecting surface antigen were present in high
      titer in sera from varicella or herpes zoster patients and paralleled titers
      obtained by the complement fixation test.

PMID- 4352457
TI  - The clinical significance of pituitary-adrenal suppression by exogenous
      corticosteroids.

PMID- 4352456
TI  - immunoglobulin and histamine-sensitivity response of mice to live Bordetella
      pertussis.
AB  - Mice injected intranasally (it.n.) and intraperitoneally (i.p.) with a nonlethal
      dose (2.5 x 10(5) colony-forming units) of live Bordetella pertussis were
      examined for 50 days for infection, respiratory tract immunoglobulins (Ig),
      changes in serum Ig, and histamine sensitivity. With mice infected it.n.,
      respiratory infection markedly declined between day 20 and day 30. Ig classes (A,
      G(1), G(2a), G(2b), but no M), which had specificity for B. pertussis, were
      present in tracheobronchial wash (TBW) by day 15; by day 50, TBW immunodiffusion
      and immunoelectrophoretic precipitin bands were more intense. A sharp rise in
      serum IgA after day 30 was the only significant change relative to controls among
      the five serum Ig examined. A high degree of histamine sensitivity developed by
      day 15 to 20 and persisted for the 50 days. With mice inoculated i.p., no
      bacteria were recovered, no Ig or only traces were found in TBW and IgA only was
      specific, and no significant changes in the serum Ig relative to controls
      occurred. Histamine sensitivity developed somewhat more slowly and to a lesser
      degree than in it.n.-injected mice but persisted for the 50 days. A similar small
      number of killed bacteria (pertussis vaccine) injected it.n. or i.p. likewise
      induced slowly developing histamine sensitivity in contrast to published reports
      of 4 to 5 day peak sensitivity and decline following i.p. injection of 10(9) or
      more killed bacteria.

PMID- 4352458
TI  - Hyperlipidemia in coronary heart disease. 3. Evaluation of lipoprotein phenotypes
      of 156 genetically defined survivors of myocardial infarction.
AB  - Although analysis of lipoprotein phenotypes is widely used to diagnose and
      classify the familial hyperlipidemias, an evaluation of this system as a method
      for genetic classification has hitherto not been published. The present study of
      156 genetically defined survivors of myocardial infarction was therefore designed
      to examine the relationship between lipoprotein phenotypes and genetic lipid
      disorders. The lipoprotein phenotypes of each survivor was determined primarily
      by measurement of his plasma triglyceride and low density lipoprotein (LDL)
      cholesterol concentrations; his genetic disorder was identified by analysis of
      whole plasma cholesterol and triglyceride levels in relatives. The mean levels of
      LDL-cholesterol discriminated statistically among the three monogenic lipid
      disorders; it was highest in survivors with familial hypercholesterolemia (261+/
      61 mg/100 ml [mean +/-SD]); intermediate in those with familial combined
      hyperlipidemia (197+/-50); and lowest in those with familial hypertriglyceridemia
      (155+/-36) (P < 0.005 among the three groups). However, on an individual basis no
      lipoprotein pattern proved to be specific for any particular genetic lipid
      disorder; conversely, no genetic disorder was specified by a single lipoprotein
      pattern. This lack of correlation occurred for the following reasons: (a)
      individual LDL-cholesterol levels frequently overlapped between disorders; (b) in
      many instances a small quantitative change in the level of either LDL-cholesterol
      or whole plasma triglyceride caused qualitative differences in lipoprotein
      phenotypes, especially in individuals with familial combined hyperlipidemia, who
      showed variable expression (types IIa, IIb, IV, or V); (c) lipoprotein phenotypes
      failed to distinguish among monogenic, polygenic, and sporadic forms of
      hyperlipidemia; (d) clofibrate treatment of some survivors with genetic forms of
      hyperlipidemia caused their levels of triglyceride and LDL-cholesterol to fall
      below the 95th percentile, thus resulting in a normal phenotype; and (e) beta
      migrating very low density lipoproteins (beta-VLDL), previously considered a
      specific marker for the type III hyperlipidemic disorder, was identified in
      several survivors with different lipoprotein characteristics and familial lipid
      distributions. These studies indicate that lipoprotein phenotypes are not
      qualitative markers in the genetic sense but instead are quantitative parameters
      which may vary among different individuals with the same genetic lipid disorder.
      It would therefore seem likely that a genetic classification of the individual
      hyperlipidemic patient with coronary heart disease made from a quantitative
      analysis of lipid levels in his relatives may provide a more meaningful approach
      than determination of lipoprotein phenotypes.

PMID- 4352459
TI  - Evidence for a common, saturable, triglyceride removal mechanism for chylomicrons
      and very low density lipoproteins in man.
AB  - Hypertriglyceridemic subjects were fed diets in which dietary fat calories were
      held constant, but carbohydrate calories were varied. Three subjects with fasting
      chylomicronemia (Type V) were given less carbohydrate and four subjects without
      fasting chylomicronemia (Type IV) were fed diets with more calories as
      carbohydrate. The restricted carbohydrate intake led to disappearance of
      chylomicronemia in those subjects who had chylomicronemia on a normal diet (Type
      V to IV). In those subjects without chylomicronemia, chylomicronemia appeared in
      response to increased carbohydrate intake (Type IV to V). Thus chylomicron
      concentrations in plasma were altered even though fat intake and presumably
      chylomicron input into plasma was kept constant. These findings provide evidence
      for saturation of chylomicron removal mechanisms by alteration of endogenous
      triglyceride-rich lipoprotein concentrations. They suggest that chylomicrons
      compete with very low density lipoproteins for similar removal mechanisms. The
      relationship between endogenous triglyceride concentration and the lipolytic
      activity in plasma following heparin was then evaluated with the use of long-term
      heparin infusions to release and maintain lipolytic activity in the circulation.
      10 subjects were placed on fatfree diets to remove circulating dietary fat. The
      plasma lipolytic rate during the heparin infusion was measured consecutively on
      different days in individuals whose triglyceride concentrations were varied by
      either increasing or decreasing calories. The lipolytic rate was curvilinearly
      related to the plasma triglyceride concentrations. This curvilinear relationship
      followed Michaelis-Menton saturation kinetics over a wide range of triglyceride
      concentrations on fat-free, high-carbohydrate diets, in multiple studies in a
      group of individuals. These studies suggest that endogenous and exogenous
      triglyceride compete for a common, saturable, plasma triglyceride removal system
      related to lipoprotein lipase.

PMID- 4352460
TI  - Identification of inorganic pyrophosphate in human platelets and its release on
      stimulation with thrombin.
AB  - Serum inorganic pyrophosphate (PPi) levels were consistently two- to threefold
      higher than plasma PPi prepared from the same blood. PPi was found in platelets
      in amounts ranging from 1.4 to 3 nmol/10(8) cells, using three different
      techniques for quantification. These levels are approximately 800 times higher
      than the mean PPi concentration in normal plasma and approximate the levels of
      ADP found in platelets by other workers. About 50% of platelet PPi was
      specifically released extracellularly after stimulation with thrombin. Timed
      release experiments showed a pattern of release that resembled that described for
      ADP and ATP. This pattern was clearly different from that shown by platelet
      calcium, serotonin, or beta-glucuronidase. Platelet inorganic pyrophosphatase was
      not released into the supernate in detectable amounts. Platelets from patients
      with nucleotide storage pool deficiency showed greatly reduced levels of PPi as
      compared with control. There was no detectable release of PPi into extracellular
      medium after thrombin addition to a suspension of these platelets.

PMID- 4352461
TI  - Glucocorticoid-binding proteins in human acute lymphoblastic leukemic blast
      cells.
AB  - The first known step in steroid hormone action is the association of the steroid
      with specific cytoplasmic steroid-binding proteins (SBP). Using a competitive
      binding assay, we detected, quantified, and partially characterized such a SBP in
      cytosol from glucocorticoid-sensitive human lymphoblastic leukemic blasts. The
      affinity of steroids for the SBP was directly related to their known killing
      potency. For example, steroids without glucocorticoid effect such as
      androstenedione, etiocholanolone, and tetrahydrocortisol were unable to displace
      radiolabeled dexamethasone from the SBP in the binding reaction. The dose
      response curve for in vitro inhibition of [(3)H]thymidine uptake in leukemic
      blasts correlated closely with the binding affinity of glucocorticoids to the
      SBP, providing additional support for an essential physiologic role for SBP in
      steroid action. SBP activity was either greatly diminished or absent in
      glucocorticoid-resistant cells. Six patients who intially had SBP in their blasts
      and were responsive to combinations of drugs including glucocorticoids no longer
      had SBP activity detectable at a time when they no longer responded to
      combinations of drugs including glucocorticoids. In vitro [(3)H]thymidine uptake
      was not inhibited by steroids in leukemic blast cells lacking SBP activity. Other
      patients who had received some antileukemic therapy including glucocorticoids and
      who still had SBP in their leukemic blasts, were still responsive to drug
      combinations that included glucocorticoids. This appears to be the first study
      demonstrating glucocorticoid receptors in a human tissue.

PMID- 4352462
TI  - Hemoglobin Abraham Lincoln, beta32 (B14) leucine leads to proline. An unstable
      variant producing severe hemolytic disease.
AB  - An unstable hemoglobin variant was identified in a Negro woman with hemolytic
      anemia since infancy. A splenectomy had been performed when the patient was a
      child. The anemia was accompanied by erythrocyte inclusion bodies and excretion
      of darkly pigmented urine. Neither parent of the proposita demonstrated any
      hematologic abnormality, and it appeared that this hemoglobin variant arose as a
      new mutation. Erythrocyte survival in the patient was greatly reduced: the
      erythrocyte t(1/2) using radiochromium as a tag was 2.4 days, and a reticulocyte
      survival study performed after labeling the cells with L-[(14)C]leucine indicated
      a t(1/2) of 7.2 days. When stroma-free hemolysates were heated at 50 degrees C,
      16-20% of the hemoglobin precipitated. The thermolability was prevented by the
      addition of hemin, carbon monoxide, or dithionite, suggesting an abnormality of
      heme binding. An increased rate of methemoglobin formation was also observed
      after incubation of erythrocytes at 37 degrees C. The abnormal hemoglobin could
      not be separated from hemoglobin A by electrophoresis or chromatography, but it
      was possible to isolate the variant beta-chain by precipitation with p
      hydroxymercuribenzoate. Purification of the beta-chain by column chromatography
      followed by peptide mapping and amino acid analysis demonstrated a substitution
      of proline for beta32 leucine. It appears likely that a major effect of this
      substitution is a disruption of the normal orientation of the adjacent leucine
      residue at beta31 to impair heme stabilization.

PMID- 4352463
TI  - Biologic and immunologic characterization and physical separation of ACTH and
      ACTH fragments in the ectopic ACTH syndrome.
AB  - Extracts of tumors from 32 patients with the ectopic ACTH syndrome were subjected
      to simultaneous bioassay and radioimmunoassays for ACTH. Radioimmunoassays were
      performed using three antisera, one of which reacts with the extreme N-terminal 1
      13 amino acid sequence of ACTH, the second with the N-terminal 1-23 sequence of
      the ACTH molecule, and the third with the C-terminal 25-39 amino acid sequence of
      ACTH. There was, in general, good correlation between bioactivity and N-terminal
      ACTH immunoreactivity. However, there were large excesses of both extreme N
      terminal and C-terminal immunoreactive materials in most tumor extracts, which
      were not found in extracts of three human pituitaries. Three tumor extracts were
      subjected to molecular sieve chromatography on Sephadex G-50 fine resin. The
      bioactive ACTH eluted in the same fractions as pituitary ACTH (mol wt
      approximately 4,500 daltons) and reacted equally in all three ACTH
      radioimmunoassay systems. The bioactive tumor ACTH was neutralized by incubation
      with the C-terminal antiserum, indicating it has an intact C-terminal sequence of
      amino acids. The next several fractions from the Sephadex column contained a
      material, mol wt approximately 3,100, which was biologically inactive and had C
      terminal immunoreactivity but no N-terminal or extreme N-terminal
      immunoreactivity. Incubation with the N-terminal 1-23 ACTH antiserum did not
      adsorb these C-terminal fragments, indicating they lacked an intact sequence of
      amino acids in this region. A smaller ACTH fragment (mol wt approximately 1,800
      daltons) eluted in still later fractions and reacted with the extreme N-terminal
      antiserum but not with the N-terminal or C-terminal antisera. It had no
      steroidogenic activity, but appeared to have significant melanocyte-stimulating
      activity. It is concluded that, in addition to an ACTH similar, if not identical,
      to pituitary ACTH, tumors of patients with the ectopic ACTH syndrome contain both
      N-terminal and C-terminal ACTH fragments.

PMID- 4352464
TI  - Evidence for complement activation via the alternate pathway in skin diseases, I.
      Herpes gestationis, systemic lupus erythematosus, and bullous pemphigoid.
AB  - A patient with herpes gestationis, 6 of 6 patients with bullous pemphigoid, and 5
      of 25 patients with systemic lupus erythematosus were found to have properdin
      deposited along the skin basement membrane.The patient with herpes gestationis
      demonstrated by immunofluorescence basement membrane deposition of C3 and C5 in
      the absence of C1q, immunoglobulins, and light chains. A second patient with
      herpes gestationis had C3 deposition with no demonstrable immunoglobulins or
      light chains. A thermolabile humoral factor(s) capable of depositing C3 (without
      C1q or C4) on normal skin basement membrane was found in the sera of both
      patients with herpes gestationis. No anti-basement membrane antibodies could be
      demonstrated in the sera of these patients.The patients with systemic lupus
      erythematosus and bullous pemphigoid who manifested properdin deposition also
      showed skin basement membrane deposits of C1q, C4, C3, C5, and immunoglobulins.
      C3 proactivator (C3PA) was also found deposited along the skin basement membrane
      of three patients with systemic lupus erythematosus and all six bullous
      pemphigoid patients. This study provides suggestive evidence that activation of
      complement is occurring via the alternate pathway in herpes gestationis. In
      systemic lupus erythematosus and bullous pemphigoid, both the classical
      (antibody) mediated activation of complement as well as the alternate pathway may
      be operative.

PMID- 4352465
TI  - Septicaemia due to Pasteurella pneumotropica.
AB  - The literature concerning Pasteurella pneumotropica infection in animals and man
      is briefly reviewed and a case presented in which the organism was the cause of
      septicaemia in a patient receiving chemotherapy for myeloid leukaemia.
      Bacteriological findings are recorded and compared with those of other authors.

PMID- 4352471
TI  - Cytomegalovirus infection. A case with meningoencephalitis.

PMID- 4352472
TI  - Malignant pulmonary neoplasms predisposing to spontaneous pneumothorax.

PMID- 4352473
TI  - In vitro effect of human lymphotoxin on microorganisms.

PMID- 4352474
TI  - On the mechanism of antiatherosclerotic agents: microchemical studies on the in
      vitro effects of pyridinol carbamate and estrogen (premarin) on
      phosphofructokinase and malate dehydrogenase in the arterial wall.

PMID- 4352475
TI  - [Use of distamycin A in the therapy of various viral cutaneous diseases due to
      VZ].

PMID- 4352476
TI  - Electron microscopic detection of simian-type virus particles in human milk.

PMID- 4352477
TI  - Psychophysiological parallels in dreams.

PMID- 4352478
TI  - REM sleep in four-month infants under home and laboratory conditions.

PMID- 4352479
TI  - The effect of intra-arterial contrast media on the small intestine of rabbits. An
      electron-microscopic study.

PMID- 4352480
TI  - [Tumors of the septum pellucidum (apropos of 7 observations)].

PMID- 4352481
TI  - Cyclic adenosine monphosphate, metabolites, and phosphorylase in neural tissue: a
      comparison a methods of fixation.
AB  - Fixation of rat brain tissue by freeze-blowing, microwave irradiation, immersion
      of whole rats in liquid nitrogen, and decapitation into liquid nitrogen indicates
      that postmortem changes in metabolites and enzyme forms are minimal in freeze
      blown brains. Cyclic adenosine monophosphate levels are lowest in microwave
      irradiated brains, which has been interpreted by some investigators to indicate
      rapid fixation and minimal anoxia. However, the changes in phosphocreatine,
      adenosine triphosphate, lactate, and phosphorylase clearly demonstrate that
      fixation by freeze-blowing or immersion in liquid nitrogen more closely
      approximate the state in vivo.

PMID- 4352483
TI  - [Leukosis and heredity].

PMID- 4352482
TI  - Biochemical and endocrinological studies in parasite-infested patients with and
      without infantilism.

PMID- 4352484
TI  - Fungal genetics.

PMID- 4352485
TI  - Synthesis and biological activity of some purine 5'-thio-5'-deoxynucleoside 3',5'
      cyclic phosphorothioates.

PMID- 4352486
TI  - Studies on the active-site sulfhydryyl groups of yeast alcohol dehydrogenase.

PMID- 4352487
TI  - An interacting spin label study of the fluidizing and condensing effects of
      cholesterol on lecithin bilayers.

PMID- 4352488
TI  - Optical analysis of electron micrographs of cytochrome oxidase membranes.

PMID- 4352489
TI  - Studies on cell-coat macromolecules in normal and virus-transformed BHK 21-C13
      cells.

PMID- 4352490
TI  - Effect of anionic surfactants, nonionic surfactants and neutral salts on the
      conformation of spin-labeled erythrocyte membrane proteins.

PMID- 4352491
TI  - The effect of different fatty acid and sterol composition on the erythritol flux
      through the cell membrane of Acholeplasma laidlawii.

PMID- 4352493
TI  - The stoichiometry of the paramagnetic copper and the oxidation-reduction
      potentials of type I copper in human ceruloplasmin.

PMID- 4352492
TI  - Characterization of hydrophobic regions in proteins by spin labeling technique.

PMID- 4352494
TI  - Purification of c-type cytochromes from Nitrosomonas europaea.

PMID- 4352496
TI  - Genital herpes simplex virus infection and gonorrhoea. Association and analogies.

PMID- 4352495
TI  - The purification and some properties of the molybdenum-iron protein of Chromatium
      nitrogenase.

PMID- 4352498
TI  - Vasopressor-induced natriuresis and altered intrarenal haemodynamics in cirrhotic
      man.

PMID- 4352497
TI  - Plasma renin activity, plasma angiotensin and plasma and urinary electrolytes in
      normal and toxaemic pregnancy, including a prospective study.

PMID- 4352499
TI  - The measurement of arginine vasopressin in human plasma by radioimmunoassay.

PMID- 4352500
TI  - Adipose tissue cellularity and metabolism in newly diagnosed juvenile diabetics.

PMID- 4352501
TI  - Interaction of tellurite with the respiratory chain in rat liver mitochondria.

PMID- 4352502
TI  - Size of the RNA's synthesized by purified calf thymus DNA-dependent RNA
      polymerases on SV40 DNA.

PMID- 4352503
TI  - The oxidation of acetate by liver mitochondria.

PMID- 4352504
TI  - A study of tRNA methylase action.

PMID- 4352505
TI  - Specific effect of estrogens on an interaction between the uterine estradiol
      receptor and DNA.

PMID- 4352506
TI  - Submitochondrial localization of DNA polymerase in rat liver tissue.

PMID- 4352507
TI  - Purification of virus glycoproteins by affinity chromatography using Lens
      culinaris phytohaemagglutinin.

PMID- 4352508
TI  - Effects of manganese on the activity of glycolytic and gluconeogenic enzymes in
      the perfused rat liver.

PMID- 4352510
TI  - [Association of scleroderma and Paget's disease].

PMID- 4352509
TI  - The significance of enzyme histochemical patterns in carcinomas of the large
      intestine in man.
AB  - The activities of 13 enzymes in 40 carcinomas of the large bowel have been
      studied using histochemical techniques. Five enzymes-non-specific esterase,
      monoamine oxidase, succinate dehydrogenase, cytochrome oxidase, and acid
      phosphatase-commonly show much less activity in the tumours than in adjacent
      normal colon. The tumours have been classified based upon the number of enzymes
      which show marked reduction in activity in each tumour (types 1-5). The enzyme
      histochemical type and the size of the tumours have been jointly correlated with
      the presence of lymph node metastasis. Small type 1 or 2 tumours do not appear to
      be associated with metastatic disease. Small type 5 tumours were commonly
      associated with secondary carcinoma in the lymph nodes. Large tumours (greater
      than 25 sq cm surface area) of any histochemical type were frequently associated
      with lymph node metastasis. Discussion of the possible reasons for these findings
      and their clinical significance is presented.

PMID- 4352511
TI  - E.P.R. of free radicals formed in DNA and its constituents after exposure to
      discharge-excited inert gases. II. Purines and DNA.

PMID- 4352512
TI  - Dysphagia, vomiting and obdurate constipation as a metabolic manifestation of
      malignancy.

PMID- 4352513
TI  - Water-soluble and pentanol-extractable proteins in human brain normal tissue and
      human brain tumours, with special reference to S-100 protein.

PMID- 4352514
TI  - The effect of ionizing radiation upon mitochondria of the central nervous system.

PMID- 4352515
TI  - Myelin subfractions in developing rat brain: characterization and sulphatide
      metabolism.

PMID- 4352516
TI  - The occurrence of a glycine cleavage system in mammalian brain.

PMID- 4352518
TI  - Availability to neuraminidase of gangliosides and sialoglycoproteins in neuronal
      membranes.

PMID- 4352517
TI  - Mitochondrial cytochrome oxidase and monoamine oxidase activities in the
      developing chick cerebral hemispheres.

PMID- 4352519
TI  - [Malignant synovialoma of the cotyle roof].

PMID- 4352520
TI  - [Role of 67Ga-citrate in the diagnosis of hepatic tumor].

PMID- 4352521
TI  - [Cholinergic transmission in the central nervous system].

PMID- 4352523
TI  - [Clinical evaluation of a preparation containing nucleosides in antineuritis
      therapy].

PMID- 4352522
TI  - Electron microscopic identification of papova virus in laryngeal papilloma.

PMID- 4352524
TI  - [Histochemical study of mixed salivary gland tumors].

PMID- 4352526
TI  - Infantile polymyoclonia.

PMID- 4352525
TI  - Bicuculline, GABA and central inhibition.

PMID- 4352527
TI  - Hyperkalaemic periodic paralysis associated with Addison's disease.

PMID- 4352528
TI  - Dysaesthesia-dyskinesia: a syndrome of painful legs and moving toes.

PMID- 4352529
TI  - Spontaneous regression of leukemia in chickens infected with avian myeloblastosis
      virus.

PMID- 4352530
TI  - Isolated pituitary cells: CRF-like activity of neurohypophysial and related
      polypeptides.

PMID- 4352531
TI  - Calcification of a lysozyme-inositol phosphatide complex in vitro.

PMID- 4352532
TI  - The effect of riboflavin deficiency on key gluconeogenic enzyme activities in rat
      liver.

PMID- 4352533
TI  - Suppression of established Friend virus leukemia by statolon. VII. Relative roles
      of interferon and the immune response in development of FV-dormant infections.

PMID- 4352534
TI  - Enhanced growth of a polyoma transformed tumor cell in Spirometra mansonoides
      infected hamsters.

PMID- 4352535
TI  - Further studies of viral antibodies in the cerebrospinal fluid of patients with
      multiple sclerosis: vaccinia and parainfluenza type 1.

PMID- 4352536
TI  - Propagation of Rauscher leukemia virus to human lymphoblastoid cells by in vivo
      diffusion chamber cultivation.

PMID- 4352537
TI  - The effect of LATS and TSH on protein and RNA synthesis in isolated thyroid
      cells.

PMID- 4352538
TI  - Body movements during sleep after sleep loss.

PMID- 4352539
TI  - Carotid body chemodectomas: recent experience at University of Alabama hospitals.

PMID- 4352540
TI  - Trans-sphenoidal surgery for pituitary lesions.

PMID- 4352541
TI  - DNA polymerases in RNA tumor viruses and possible "protoviruses".

PMID- 4352542
TI  - The presence and expression of RNA tumor virus genes in normal and infected
      cells: detection by molecular hybridization.

PMID- 4352543
TI  - Introductory review. Molecular mechanisms in viral neoplasia of animals and their
      implications in the origin of cancer in man.

PMID- 4352544
TI  - Evidence for viral involvement in murine and human mammary adenocarcinoma.

PMID- 4352545
TI  - Evidence for 30-40S RNA as precursor of the 60-70S RNA of Rous sarcoma virus.

PMID- 4352546
TI  - Molecular evidence for a viral etiology of human leukemias, lymphomas, and
      sarcomas.

PMID- 4352547
TI  - Molecular probes in studies of the relationship of viruses to human neoplasia.

PMID- 4352548
TI  - Animal model of human disease: primary hepatocellular carcinoma.

PMID- 4352551
TI  - Duodenal wall tumors and the Zollinger-Ellison syndrome. Surgical management.

PMID- 4352550
TI  - Gastrontestinal cytomegalovirus infection.

PMID- 4352549
TI  - Interaction of angiotensin with disseminated intravascular coagulation: a
      possible mechanism in the genesis of acute renal failure.
AB  - Because of the importance of the renin-angiotensin system in renal homeostatic
      mechanisms, the effect of angiotensin administration upon disseminated
      intravascular coagulation has been studied in rabbits. An infusion of angiotensin
      II (0.1 mug/kg/min for 2 hours) produced neither histologic abnormalities in the
      kidneys nor an elevation of creatinine. After an infusion of thrombin (2.0
      units/kg/min for 2 hours) only 3 of 10 rabbits, when sacrified 24 hours later,
      showed histologic lesions comprised of occasional fibrin thrombi and foci of
      tubular necrosis. Creatinine levels did not rise. In contrast, the combination of
      angiotensin and thrombin resulted in renal lesions in 12 of 14 animals. Four had
      frank cortical necrosis, while combinations of tubular necrosis, glomerular
      thrombosis and segmental glomerular infarction occurred in the others, together
      with elevated creatinine levels. Blockade of alpha-adrenoreceptors with
      phenoxybenzamine in 12 animals did not prevent either these histologic changes or
      creatinine elevation, showing that the effect of angiotensin was independent of
      alpha-adrenoreceptor stimulation. The synergistic interaction between angiotensin
      and disseminated intravascular coagulation was not explained by differences in
      the consumption of plasma fibrinogen but apparently was due to localization of
      fibrin thrombi within glomerular capillaries by the vasomotor actions of
      angiotensin, as has previously been shown to occur with alpha-adrenoreceptor
      simulation. Such a mechanism might contribute to renal glomerular deposition of
      fibrin in acute ischemic renal failure.

PMID- 4352552
TI  - A soluble CO-binding c-type cytochrome from the marine bacterium Beneckea
      natriegens.

PMID- 4352553
TI  - Biochemical and biophysical studies on cytochrome c oxidase. X. Spectral and
      potentiometric properties of the hemes and coppers.

PMID- 4352554
TI  - [Distribution of enzymes and cytochromes in Candida tropicalis cultured on
      alkanes].

PMID- 4352555
TI  - Inhibition of 5 -reductase activity of rat prostate by estradiol derivatives.

PMID- 4352556
TI  - [Course and control of sexual development in female swine. 3. Induction of
      ovulation and the isolation of ova in female swine of the German Land breed at
      the age of 15 weeks].

PMID- 4352557
TI  - [Contrast flow rates in the superior mesenteric arterial territory].

PMID- 4352559
TI  - [The effect of pregnancy on function of the upper urinary tracts, as shown by
      excretion urography].

PMID- 4352558
TI  - [Differential diagnosis of hypervascularized kidney tumors].

PMID- 4352560
TI  - [Radiography of colonic anastomoses and of recurrences at the anastomoses
      following colonic cancer resection].

PMID- 4352561
TI  - [Significance of metaphyseal ossification disorders in infancy, with special
      reference to infectious fetal diseases].

PMID- 4352563
TI  - [Thanatophoric dwarfism].

PMID- 4352562
TI  - [Radiodiagnosis of skeletal changes in the Ellis-van-Creveld syndrome during the
      growth period. (Analysis of the literature and report of 2 personal
      observations)].

PMID- 4352564
TI  - [The lymphographic diagnosis of multiple bone lymphangiomatosis].

PMID- 4352566
TI  - [Value of detail enhancement in the diagnosis of navicular bone fractures].

PMID- 4352565
TI  - [Objectification of a lymphographic finding of hypoplastic lymph nodes by the
      Elke volume determination method].

PMID- 4352568
TI  - [Problems of the "normal" liver scan].

PMID- 4352567
TI  - [Radiological determination of mineral equivalents in bone. 3. A universally
      available exact mineral-equivalent measuring device for the determination of
      decalcification processes in finger bones].

PMID- 4352569
TI  - [Follow-up studies on liver injuries using scintiscans].

PMID- 4352570
TI  - [The principle for the geometric method of quantitative double detector scans.
      Further attempts at complete correction of attenuation].

PMID- 4352571
TI  - [Gastroesophageal invagination. Case report and review of literature].

PMID- 4352572
TI  - [Intraluminal duodenal diverticulum with concomitant pancreatitis and
      simultaneous ascariasis].

PMID- 4352573
TI  - [Pneumatosis cystoides intestinalis. 2 cases with colonic involvement].

PMID- 4352574
TI  - [Gardner's syndrome. Radiography and clinical contribution].

PMID- 4352575
TI  - The pneumonocytes in the lung of Xenopus laevis.

PMID- 4352576
TI  - Measurement of inorganic pyrophosphate in biological fluids. Elevated levels in
      some patients with osteoarthritis, pseudogout, acromegaly, and uremia.
AB  - A rapid and relatively simple method for measurement of inorganic pyrophosphate
      (PPi) in biological samples has been described. The mean +/-SEM of plasma samples
      from 94 normal subjects was 1.8+/-0.06 muM, giving a normal range (99% confidence
      limits) of 0.16 - 3.40 mumol/liter. Analysis of 17 plasma samples in duplicate
      showed a standard deviation of 0.18, giving a 99% probability that a single
      determination of plasma PPi would be +/-0.68 muM of the true value. The mean PPi
      levels in plasma from subjects with osteoarthritis, pseudogout, acromegaly, and
      uremia were significantly greater than the normal mean (P < 0.01). Samples from
      rheumatoid arthritis showed PPi levels distributed about a mean identical to the
      normal mean. Plasma inorganic orthophosphate levels correlated positively with
      PPi levels in samples from normal subjects and in samples from patients with
      osteoarthritis, pseudogout, and uremia, but not with acromegaly. This correlation
      was statistically significant only in the normal samples and in those from
      patients with osteoarthritis.

PMID- 4352577
TI  - Simulation of tissue properties in irreversible diffuse obstructive pulmonary
      syndromes. Enzyme digestion.
AB  - The length-tension properties of alveolar wall from normal cats were studied
      before and after exposure to enzymes naturally found in mammals (elastase,
      trypsin, collagenase, hyaluronidase). Hyaluronidase effected little change while
      all the proteolytic enzymes altered the mechanical properties of lung tissue.
      Collagenase removed the "mechanical stop" and the alveolar walls fractured at low
      forces. The properties of wall exposed to trypsin resembled those of elastase
      treated tissue. Elastase increased the extension necessary to reach a given force
      and increased the maximum length (L(max)) and resting length (L(o)). Maximum
      extensibility (lambda(max)), the ratio of L(max) to L(o), fell with both elastase
      and trypsin digestion. A reduction in lambda(max) simulates the changes in
      alveolar wall properties seen in the lungs of the aged and in those with an
      irreversible diffuse obstructive pulmonary syndrome (DOPS(I)). Unlike these
      states, however, the energy loss in stretching alveolar wall increased with
      elastolysis. Furthermore, the changes in L(o) necessary to effect a change in
      lambda(max) of alveolar wall comparable to that seen in DOPS(I) were excessive.
      The altered tissue properties that occur in man with obstructive pulmonary
      syndromes could not be produced with these proteolytic enzymes or with
      hyaluronidase.

PMID- 4352578
TI  - Regulation of adrenal ornithine decarboxylase by adrenocorticotropic hormone and
      cyclic AMP.
AB  - Adrenal ornithine decarboxylase activity was stimulated in a dose-related manner
      after administration of ACTH or dibutyryl ((6)N-2'-O-dibutyryl) cyclic AMP to
      hypophysectomized rats. Little effect was observed for 2 h, but striking
      increases in enzyme activity were observed 4 h after administration of these
      substances. Effects of ACTH and dibutyryl cyclic AMP were not secondary to
      stimulation of steroidogenesis, since hydrocortisone had no effect on adrenal
      ornithine decarboxylase although it did stimulate activity of the enzyme in the
      liver and kidney.ACTH, given subcutaneously to hypophysectomized rats, induced
      striking increases in adrenal cyclic AMP levels within 15-30 min with a fall
      towards the base line in 1 h. Increases in ornithine decarboxylase activity lag
      several hours after this endogenous cyclic AMP peak, in contrast to the
      stimulatin of steroidogenesis by the nucleotide that requires only 2-3 min. After
      graded doses of ACTH, increases in adrenal cyclic AMP levels at 30 min were
      paralleled by proportional increases in adrenal ornithine decarboxylase activity
      4 h after hormone treatment. Whereas maximal levels of adrenal steroidogenesis
      have been observed at tissue cyclic AMP levels of 6 nmol/g. ACTH is capable of
      inducing increases in nucleotide levels up to 200 nmol/g or more. These high
      tissue levels of cyclic AMP, although unneccessary for maximal steroidogenesis,
      appear to stimulate adrenal ornithine decarboxylase activity. Several results in
      addition to the time lag in the stimulation of ornithine decarboxylase activity
      suggest a mechanism involving accumulation of the enzyme or some factor needed
      for its activity rather than direct activation of the enzyme by cyclic AMP. Thus,
      the addition of cyclic AMP directly to the ornithine decarboxylase assay mixture
      in vitro was without stimulatory effect. In addition, actinomycin D or
      cycloheximide in doses sufficient to block adrenal RNA and protein synthesis,
      respectively inhibited the stimulation of ornithine decarboxylase activity by
      ACTH in vivo. An adrenocortical cancer was found to maintain ornithine
      decarboxylase activity at very high levels, but did so at much lower cyclic AMP
      levels than those of ACTH-stimulated adrenals. It is concluded that ACTH
      stimulates adrenal ornithine decarboxylase activity and that this effect may be
      mediated by cyclic AMP. However, cyclic AMP be mediated by appear to be a
      determinant of the high level of enzyme activity found in adrenocortical cancer.

PMID- 4352581
TI  - An experimental radiopaque composite material.

PMID- 4352580
TI  - Disparate enzyme activity in erythocytes and leukocytes. A variant of
      hypoxanthine phosphoribosyl-transferase deficiency with an unstable enzyme.
AB  - A family is reported in which each of two sisters has a son with no detectable
      hypoxanthine phosphoribosyltransferase (HPRT) (EC 2. 4. 2. 8) in his
      erythrocytes, a finding considered pathognomonic of Lesch-Nyhan disease. However,
      neither has the stigmata of the disease. One boy is neurologically normal, and
      the other is moderately retarded. There was only a slight increase in urinary
      uric acid, but the amounts of hypoxanthine and xanthine, and their ratios, were
      similar to those found in Lesch-Nyhan disease, strongly indicating that excesses
      of these last two oxypurines are not responsible for the symptomatology in that
      disease. In contrast to the nondetectable HPRT activity in the red blood cells,
      leukocyte lysates from the two boys have 10-15% of normal activity, possibly
      reflecting continuing synthesis of an unstable enzyme. This hypothesis is
      supported by the demonstration that at 4 degrees C HPRT activity was rapidly lost
      in the propositus while the activity increased in control subjects. The mother's
      cells were intermediate between the two. The intact and disrupted leukocytes of
      the hemizygote, in the absence of added phosphoribosyl converted as much
      hypoxanthine to inosinate as the normal cell, and appropriate tests indicated
      that under these circumstances enzyme concentration is not rate limiting whereas
      the concentration of the cosubstrate, phosphoribosyl pyrophosphate, is. The
      capacity for normal function in the intact mutant cell is more representative of
      in vivo conditions than the lysate, which may explain the important modification
      of clinical symptomatology, the relatively mild hyperuricosuria, and the presence
      of mosaicism in the circulating blood cells of the heterozygotes. A similar
      explanation may apply to other genetic diseases in which incomplete but severe
      enzyme deficiencies are found in clinically normal individuals. An associated
      deficiency in glucose-6-phosphate dehydrogenase in this family permitted
      confirmation of previous observations on linkage with hypoxanthine
      phosphoribosyltransferase.

PMID- 4352579
TI  - Development of intestinal adenyl cyclase and its response to cholera enterotoxin.
AB  - Adenyl cyclase activity in intestinal membranes has been studied during
      development in the rabbit fetus from fetal day 17 to 10 days postnatally and in
      the human fetus from the 10th to the 17th wk of gestation. In the rabbit, the
      enzyme was already present by fetal day 17 and showed a fourfold peak rise in
      specific activity by 22 days. By 28 days, the specific activity had fallen toward
      adult levels and remained constant throughout gestation and the 1st wk of life.
      Fluoridestimulated activity showed a similar curve, and was 2.5-5 times the basal
      values. Activities in jejunum and ileum were comparable at all time points
      studied. Phosphodiesterase activity did not change during gestation. When fetal
      intestinal segments were incubated in vitro with purified cholera enterotoxin,
      adenyl cyclase activity in subsequently prepared membranes was increased two- to
      threefold. This level was not regularly further elevated by fluoride ion. Lithium
      ion inhibited both the basal and fluoride-stimulated enzyme activity in membranes
      prepared from rabbit fetuses at term. Lactase activity (reflecting the
      development of the microvilli) in either whole intestinal homogenates or in the
      membrane fractions showed a differnet pattern of development, with a rise
      beginning on fetal day 24 and a plateau just after birth. In intestinal membranes
      prepared from human fetuses, the activity of both basal and fluoride-stimulated
      adenyl cyclase tripled from the 10th to the 17th wk of gestation. The data both
      in the rabbit and in man show that intestinal adenyl cyclase is capable of
      responding to cholera enterotoxin quite early in gestation. In the rabbit, this
      occurs before the time of appearance or ville or of an enzyme marker (lactase)
      for microville. The results support the concept that adenyl cyclase is present in
      plasma membrane other than the brush border.

PMID- 4352582
TI  - Petrographic study of the refractory performance of high-fusing dental alloy
      investments. II. Silica-bonded investments.

PMID- 4352583
TI  - Mutants of nonproducer cell lines transformed by murine sarcoma viruses. I.
      Induction, isolation, particle production, and tumorigenicity.
AB  - A variety of cell mutants were obtained by a single 5'-bromodeoxyuridine (BrdU)
      treatment of an nonproducer (NP) cell line transformed by the Kirsten strain of
      murine sarcoma virus (Ki-MSV). Isolation procedures of these cell See PDF for
      Structure mutants are described. The cell mutants obtained were classified by
      tumorigenic potential and shedding of Type C virus particles. The cell mutants
      were classified into four groups: (A) tumorigenic, without particles; (B)
      tumorigenic, with Type C particles; (C) nontumorigenic, without particles; and
      (D) nontumorigenic, with Type C particles. The tumorigenic cell lines showed
      variability in morphology with both flat and typical transformed appearing cell
      lines showing equal transplantability.

PMID- 4352584
TI  - The modulating influence of cyclic nucleotides upon lymphocyte-mediated
      cytotoxicity.
AB  - The capacity of allosensitized thymus-derived lymphocytes to destroy target cells
      bearing donor alloantigens is modulated by the cellular levels of cyclic AMP and
      cyclic GMP. Increases in the cyclic AMP levels of attacking lymphocytes by
      stimulation with prostaglandin E(1), isoproterenol, and cholera toxin inhibit
      lymphocyte-mediated cytotoxicity; whereas, depletion of cyclic AMP with imidazole
      enhances cytotoxicity. The augmentation of cytotoxicity produced by cholinergic
      stimulation with carbamylcholine is not associated with alterations in cyclic AMP
      levels and is duplicated by 8-bromo-cyclic GMP. The effects of activators of
      adenylate cyclase, cholinomimetic agents, and 8-bromocyclic GMP are upon the
      attacking and not the target cells and occur at the time of initial interaction
      of attacking and target cells. Indeed, the level of cyclic nucleotide (cyclic AMP
      and cyclic GMP) at the time of initial cell-to-cell interaction determines the
      extent of cytotoxicity.

PMID- 4352585
TI  - Observations on the microbiological flora of canned Parma ham.
AB  - A significant proportion of a consignment of branded Parma Ham was found to have
      ;blown' tins; the associated bacterial flora was therefore investigated. No
      Salmonella or Shigella were found. Clostridium welchii type A and Clostridium
      bifermentans were isolated in moderate numbers only from enrichment cultures of
      the ham. Staphylococcus spp. and coryneform bacteria were obtained from all tins
      and Group D streptococci were present in a few. No food-poisoning cases were
      associated with this ham.

PMID- 4352586
TI  - Lipid A: chemical structure and biological activity.

PMID- 4352587
TI  - Immunologic and antineoplastic effects of endotoxin: role of membranes and
      mediation by cyclic adenosine-3',5'-monophosphate.

PMID- 4352588
TI  - Effects of endotoxin on macrophages and other lymphoreticular cells.

PMID- 4352589
TI  - Radiotherapy of glioblastoma multiforme.

PMID- 4352590
TI  - Intravenous radionuclide hepatography in the differential diagnosis of
      intrahepatic mass lesions.

PMID- 4352591
TI  - Evaluation of vitamin D supplements by biological assay using the turkey.

PMID- 4352592
TI  - The in-vitro effects of silica-treated hamster macrophages on collagen production
      by hamster fibroblasts.

PMID- 4352593
TI  - Triple carcinoma of the breast, one arising within a fibro-adenoma.

PMID- 4352594
TI  - Androblastoma of the ovary with heterotopic elements.

PMID- 4352596
TI  - Secretion and uptake of peroxidase by rat adenohypophyseal cells.

PMID- 4352597
TI  - Conservative management of the infected pacemaker pulse generator.

PMID- 4352598
TI  - Studies of the myocardial metabolism of free radicals in the myocardial
      infarction (with electron spin resonance (ESR) spectrometry).

PMID- 4352595
TI  - Lactic dehydrogenase and other enzymes in the mouse uterus during the peri
      implantation period of pregnancy.

PMID- 4352599
TI  - [Calcitonin. Physiology; therapeutic importance].

PMID- 4352601
TI  - Delayed dermal hypersensitivity to autologous lymphocytes in multiple sclerosis.

PMID- 4352600
TI  - [Glomus jugulare tumors].

PMID- 4352602
TI  - Myasthenia gravis lacking response to cholinergic drugs.

PMID- 4352603
TI  - Nervous system lesions after sting by yellow jacket. A case report.

PMID- 4352604
TI  - [Acquired cytomegalic inclusion disease with autoimmune hemolytic anemia].

PMID- 4352605
TI  - [Anticytomegalovirus antibody in children from Teheran].

PMID- 4352606
TI  - [Changes in the structure of irradiated phosphofructokinase].

PMID- 4352607
TI  - [Virological study of residual waters. Its importance in epidemiology].

PMID- 4352608
TI  - [Progressive systemic sclerosis (scleroderma) associated with pulmonary cancer.
      Report of 4 further cases].

PMID- 4352610
TI  - [Mediators of biological responses at the cellular level. The cyclic
      nucleotides].

PMID- 4352609
TI  - Vasopressin: possible role of microtubules and microfilaments in its action.
AB  - Colchicine, vinblastine, podophyllotoxin, and cytochalasin B inhibit the action
      of vasopressin and cyclic adenosine monophosphate on osmotic water movement
      across the toad bladder. The findings suggest that microtubules, and possibly
      microfilaments, play a role in the action of vasopressin, perhaps through
      involvement in the mechanism of release of secretory material from the bladder
      epithelial cells.

PMID- 4352611
TI  - Poliomyelitis vaccination of infants: preimmunization status and seroconversion.
AB  - A study was carried out in Delhi on the preimmunization status of infants aged 2
      6 months with regard to poliomyelitis and on seroconversion after the
      administration of oral poliomyelitis vaccine. It was found that 30.3% of the 204
      infants included in the study excreted enteroviruses, 58% of which were found to
      be polioviruses. Of 197 sera examined for neutralizing antibodies against
      different types of poliovirus, 73% were found to be triple negative and only 4.0%
      triple positive. Three doses of oral poliomyelitis vaccine were administered at
      intervals of 1 month. It was found that 71.8% of the vaccinated infants excreted
      cytopathogenic agents in the 7 days following the first dose; 80.4% of these
      agents were found to be polioviruses. Seroconversion was studied in 71 infants,
      and good antibody responses to all three types of poliovirus were observed.

PMID- 4352612
TI  - The second international reference preparation of viomycin.
AB  - The first International Reference Preparation of Viomycin was replaced by the
      second international reference preparation, consisting of material from the batch
      that provided the second Working Standard of the US Food and Drug Administration.
      The International Unit of viomycin was redefined as the activity contained in
      0.0012285 mg of the second international reference preparation. Examination of
      batches of viomycin sulfate from the various sources of production showed that
      the second international reference preparation was suitable for their assay,
      whereas a sample previously proposed as the international standard of viomycin
      was unsatisfactory.

PMID- 4352613
TI  - Pyruvate carboxylase in the developing chick embryo.

PMID- 4352615
TI  - Adenocarcinoma of the colon associated with ureterosigmoidostomy: report of a
      case.

PMID- 4352614
TI  - Causes and prevention of colonic anastomotic breakdown.

PMID- 4352616
TI  - [For patient and parents in apparent recurrence of urinary tract infection in the
      child. 2. Significance of in apparent recurrence in the convalesence of children
      following acute urinary tract infection].

PMID- 4352617
TI  - [Isolation of FMD virus type A carrier from cattle].

PMID- 4352618
TI  - [Clinical experience with immunotherapy of malignant tumors].

PMID- 4352619
TI  - Effect of pentagastrin on adult rat duodenal cells in culture.

PMID- 4352620
TI  - Hepatic changes in adult alpha-1-antitrypsin deficiency.

PMID- 4352621
TI  - [Adenolymphography and endolymphatic radiotherapy in malignant lymphoma].

PMID- 4352622
TI  - Induction of tryptophan oxygenase in Cicer arietinum seedlings by indole-3-acetic
      acid & cyclic 3',5'-adenosine monophosphate.

PMID- 4352623
TI  - Mechanisms of inhibition and activation of beef liver D-glycerate dehydrogenase
      by inorganic anions.

PMID- 4352624
TI  - Kinetic studies on the G-factor-dependent uncoupled GTPase of ribosomes.

PMID- 4352626
TI  - Purification and some properties of G-factor from the silk gland of silkworm.

PMID- 4352627
TI  - Effect of calcium ion on lipase-fat complex formation.

PMID- 4352625
TI  - Isolation and characterization of glycopeptides from rat liver nuclear membrane.

PMID- 4352628
TI  - Studies on proteolytic enzymes (pronase) of Streptomyces griseus K-1. 3.
      Purification and proteolytic specificity of alkaline proteinase C from pronase.

PMID- 4352629
TI  - DNA dependent RNA polymerase from Ehrlich ascites tumor cells. II. Factors
      stimulating the activity of RNA polymerase II.

PMID- 4352630
TI  - Serum thyrotropin (TSH) in pituitary and-or hypothalamic hypothyroidism: normal
      or elevated basal levels and paradoxical responses to thyrotropin-releasing
      hormone.

PMID- 4352632
TI  - Maternal-fetal ACTH relationship in man.

PMID- 4352631
TI  - Oat-cell carcinoma of the lung simultaneously producing ACTH and serotonin.

PMID- 4352634
TI  - [Transmission block in neuromuscular diseases--my research method and theory].

PMID- 4352633
TI  - Radioreceptor assay for growth hormone.

PMID- 4352635
TI  - [Transmission block in neuromuscular diseases--our research methods and theory].

PMID- 4352636
TI  - [Harvey-Masland test].

PMID- 4352637
TI  - [Clinicopathological conference: a case presenting symptoms of cognition disorder
      and spasm and resulting in sudden death due to gastrointestinal hemorrhage].

PMID- 4352638
TI  - [Comparative evaluation of the tolbutamide and leucine tests in insulinoma].

PMID- 4352639
TI  - Catecholamine transmitter for salivary secretion in the cockroach.

PMID- 4352641
TI  - Gonadotropin and steroid hormone excretion in trophoblastic neoplasia.

PMID- 4352642
TI  - Spontaneous regression of Bowenoid atypia of the vulva.

PMID- 4352640
TI  - Neoplasm induction by murine type-C viruses passaged directly from spontaneous
      non-lymphoreticular tumours.

PMID- 4352643
TI  - Metastatic and secondary tumors of the vulva.

PMID- 4352644
TI  - A comparative evaluation of the distribution of concanavalin A-binding sites on
      the surfaces of normal, virally-transformed, and protease-treated fibroblasts.
AB  - The topographical distributions of concanavalin A-binding sites on the surfaces
      of 3T3, proteasetreated 3T3, and simian virus 40-transformed 3T3 cultured mouse
      fibroblasts appear to be different, as shown by a shadow-cast replica technique
      using concanavalin A and a hemocyanin marker, or as shown previously on isolated
      membranes with concanavalin A coupled to ferritin. However, chemical fixation of
      cells before labeling with concanavalin A and hemocyanin, or labeling exclusively
      at 4 degrees , allows one to distinguish between inherent concanavalin A-binding
      site topography and potential rearrangement of sites induced by the action of the
      multivalent concanavalin A molecule itself. The inherent distribution of binding
      sites on 3T3, protease-treated 3T3, and transformed cells is actually the same on
      all cells, i.e., dispersed and random. Treatment of unfixed transformed or
      protease-treated 3T3 cells, but not normal 3T3 cells, with concanavalin A and
      hemocyanin at 37 degrees (or at 4 degrees with subsequent warming to 37 degrees
      ), however, results in clustering of binding sites, presumably due to
      crosslinking of neighboring lectin-binding sites by the quadrivalent concanavalin
      A. Thus, the underlying difference between concanavalin A-binding sites on normal
      as compared with transformed or protease-treated normal cells lies not in the
      inherent topography of binding sites, but rather in the susceptibility of the
      sites to aggregation by concanavalin A. The latter may reflect an increased
      mobility of lectin-binding sites on transformed or protease-treated cells.

PMID- 4352645
TI  - Response of Dictyostelium plasma membranes to adenosine 3':5'-cyclic
      monophosphate.
AB  - Myxamoebae of the cellular slime mold Dicytostelium discoideum aggregate in
      response to a chemotactic substance identified as adenosine 3':5'-cyclic
      monophosphate. Upon aggregation cell division is suppressed, the cells become
      adhesive, and differentiation is initiated. Freeze-fracture studies of myxamoebae
      were conducted to determine the effect of cyclic AMP and calcium on plasma
      membrane ultrastructure. The inner surfaces of the plasma membranes exhibited
      particulate structures whose sizes (43-187 A) and frequency distribution were
      determined. Cyclic AMP and calcium induced within 2 hr the formation of particles
      having average diameters 1.7-times and 1.5-times greater, respectively, than
      those of the vegetative myxamoebae controls. These data suggest that cyclic AMP
      mobilizes the intracellular calcium which may be effective in changing plasma
      membrane structure.

PMID- 4352646
TI  - "Early" virus-specific RNA may contain information necessary for chromosome
      replication and mitosis induced by Simian Virus 40.
AB  - Simian Virus 40 (SV40) induces in "contact-inhibited" tissue culture cells of
      mouse kidney an abortive infection that leads to the appearance of intra-nuclear
      SV40-specific tumor (T-) antigen, followed by replication of the mouse-cell
      chromatin and mitosis, while no viral progeny DNA or capsid protein is produced.
      Synthesis of "early" SV40-specific RNA ("19S RNA") begins a few hours before the
      appearance of T-antigen and appears to be switched off after the onset of
      chromatin replication. As the most simple working hypothesis that can account for
      the experimental results available, we assume that early SV40 RNA contains
      information necessary for production of T-antigen and that this antigen (or an
      unknown early virus-specific function that would simply parallel the appearance
      of T-antigen) activates or de-inhibits a cellular regulatory element that governs
      chromosome replication and mitosis. The experimental results agree with the idea
      that SV40 acts primarily as a mitogen.

PMID- 4352647
TI  - Pleiotypic control by cyclic AMP: interaction with cyclic GMP and possible role
      of microtubules.
AB  - Previous studies have shown that exogenous dibutyryl cyclic AMP inhibits the
      uptake of uridine, leucine, and 2-deoxyglucose by cultured mouse fibroblasts.
      3':5'-cyclic GMP is shown here to counteract these inhibitory effects as well as
      the inhibition of precursor transport and leucine incorporation into proteins
      produced by prostaglandin E(1). We conclude, therefore, that cyclic GMP
      antagonizes the "pleiotypic" effects of cyclic AMP in these cells. Colcemid and
      vinblastine, but not cytochalasin B, reverse the transport inhibition caused by
      cyclic AMP without affecting the intracellular concentrations of cyclic AMP.
      These results suggest the possibility that cyclic AMP regulates the membrane
      transport of certain substrates by influencing the organization of microtubules.

PMID- 4352648
TI  - Cell contact-dependent increase in membrane D-galactopyranosyl-like residues on
      normal, but not virus- or spontaneously-transformed, murine fibroblasts.
AB  - Ricinus communis agglutinin (a lectin specific for beta-D-galactopyranosyl-like
      oligosaccharide residues) was used to investigate differences in lectin-binding
      sites on normal 3T3 and transformed SV3T3 and 3T12 cells grown to various cell
      densities in culture. The agglutinability of SV3T3 cells by R. communis
      agglutinin decreased when cells were grown to confluency or to a point where the
      cells were in contact. The agglutinability of 3T3 cells also decreased at
      confluency, but this result was variable and not as dramatic as with SV3T3 cells.
      Saturation-binding experiments performed at 4 degrees with (125)I-labeled R.
      communis agglutinin were used to monitor the number of lectin-binding sites on
      cells grown to different densities. Transformed cells (SV3T3 and 3T12) did not
      show cell-culture density-dependent changes in R. communis sites; sparse,
      touching, and confluent transformed cells had equivalent numbers of sites.
      However, touching (or confluent) 3T3 cells possessed 2.5-times the number of R.
      communis sites per cell compared to growing, sparsely populated 3T3 cells. When
      growing sparse 3T3 cells are compared to growing SV3T3 or 3T12 cells, there are 5
      times R. communis sites per unit surface area on the transformed cells. The
      change in R. communis sites during cell growth in culture is discussed in
      relation to membrane fluidity and topography of plasma membrane oligosaccharides
      and glycosyl transferases, which can modify cell surfaces at contact.

PMID- 4352649
TI  - A general method of gene isolation.
AB  - A general method of gene isolation has been developed that involves the chemical
      linkage of RNA to cellulose by a water-soluble carbodiimide, and the continuous
      circulation of DNA containing specific sequences complementary to the RNA. The
      temperature of the cellulose matrix is maintained at 37 degrees (50% formamide,
      0.3 M NaCl-0.03 M Na(3) citrate) to allow efficient DNA-RNA interaction in the
      stationary phase, while unreacted and any reassociated DNA is denatured at 90
      degrees and then recirculated into the hybridization chamber. Between 40 and 45%
      of fragmented (32)P-labeled simian virus (SV)40 DNA was removed from the
      circulating solution when cellulosebound SV40-specific RNA, assymmetrically
      transcribed in vitro with Escherichia coli RNA polymerase, was used. In the
      presence of 10(4)-fold excess of sheared E. coli DNA, nearly half of the
      [(32)P]SV40 DNA was recovered from the mixture as a DNA-RNA hybrid with
      negligible contamination by bacterial DNA. The isolation procedure is almost
      quantitative for the complementary DNA. The efficiency and selectivity of this
      method permit the isolation of a defined DNA sequence from a large and complex
      genome.

PMID- 4352651
TI  - A new enzymatic assay for guanosine 3':5'-cyclic monophosphate and its
      application to the ductus deferens of the rat.
AB  - A sensitive enzymatic procedure has been developed for the determination of
      guanosine 3':5'-cyclic monophosphate (cyclic GMP). It is based on the conversion
      of cyclic GMP to GMP by cyclic nucleotide phosphodiesterase and on the transfer
      of (32)P from [gamma-(32)P]ATP to GMP by the action of a specific ATP:GMP
      phosphotransferase (EC 2.7.4.8). The [(32)P]GDP is separated from the remaining
      [(32)P]ATP by enzymatic degradation of ATP by myosin and by precipitation of the
      (32)P(i) formed. The reaction blank, which is mostly caused by the nucleotide
      content of the enzymes, is doubled by about 0.1 pmol of cyclic GMP. The procedure
      has advantages in speed and/or accuracy over other methods in current use. Cyclic
      nucleotide concentrations were studied in the ductus deferens of the rat; two
      agents were used, carbachol and norepinephrine, which cause contraction.
      Incubation with 0.1 mM carbachol caused a 3-fold increase in cyclic GMP content,
      which was maximal about 2 min after carbachol addition. Cyclic AMP concentrations
      were not significantly changed. Addition of 0.01 mM norepinephrine increased
      cyclic GMP content by about 25% within 1 min and by 40% within 3 min; cyclic AMP
      concentrations were only slightly increased. A 3-min incubation with the
      phosphodiesterase inhibitor 1-methyl-3-isobutylxanthine (0.1 mM) doubled the
      cyclic GMP content and increased cyclic AMP concentration by 50%.

PMID- 4352650
TI  - Reduction of ferricytochrome c by dithionite ion: electron transfer by parallel
      adjacent and remote pathways.
AB  - The kinetics of the reduction of horseheart ferricytochrome c by sodium
      dithionite (phosphate buffer-sodium chloride; pH 6.5, mu = 1.0, 25 degrees )
      features two reaction pathways; one with the rate constant k(3) = 1.17 x 10(4) M(
      1) sec(-1), the other with the rate constant k(1)k(2)/k(-1) = 6.0 x 10(4) M(-1)
      sec(-1). These pathways are interpreted in terms of remote attack (possibly by
      way of the exposed edge of the porphyrin system) and adjacent attack (requiring
      the opening of the heme crevice). The limiting rate for the adjacent pathway
      (k(1) = 30 sec(-1)) is in good agreement with the rate of heme-crevice opening of
      ferricytochrome c determined in other studies. The implication of the adjacent
      attack pathway to the function of cytochrome c in vivo is discussed.

PMID- 4352652
TI  - Cytochalasin blocks sympathetic ganglionic transmission: a presynaptic effect
      antagonized by pyruvate.
AB  - The mold metabolite cytochalasin B blocked transmission through the perfused
      superior cervical sympathetic ganglion of the cat. Acetylcholine injected close
      arterially during block continued to excite the ganglion cells so that failure
      was presynaptic and, by inference, due to reduced output of acetylcholine from
      the preganglionic nerves. This blocking effect of cytochalasin was reduced by
      pyruvate. It is concluded that cytochalasin inhibits cholinergic nervous function
      and it does so, at least in part, by depressing energy production at some stage
      before pyruvate formation. One possibility is a block of glucose uptake for which
      there is evidence from other cell types. A more general conclusion is that
      inhibitory effects of cytochalasin on other secretory systems may also involve
      such a metabolic component and do not necessarily reflect an interaction of the
      drug with microfilaments as has been commonly supposed.

PMID- 4352653
TI  - Identification of a large polypeptide precursor of avian oncornavirus proteins.
AB  - Antibody to partially disrupted avian myeloblastosis virus was used to
      selectively precipitate newly synthesized intracellular viral polypeptides from
      extracts of infected chicken cells. When analyzed by sodium dodecyl sulfate-gel
      electrophoresis, immune precipitates from extracts of cells pulse-labeled for 10
      min with [(35)S]methionine contain none of the major virion polypeptides. Instead
      they show prominent viral specific polypeptides of molecular weight 76,000 and
      12,000, as well as minor quantities of other labeled polypeptides. From pulse
      chase kinetics and two-dimensional tryptic finger-prints it appears that the
      large polypeptide is a precursor of at least the two major virion proteins of
      molecular weights 24,000 and 11,000, while the smaller is a precursor of the
      11,000-dalton virion protein.

PMID- 4352654
TI  - Membrane changes and adenosine triphosphate content in normal and malignant
      transformed cells.
AB  - Transformed fibroblasts had a low content of ATP when grown at a high cell
      density and a high content of ATP when grown at a low cell density. Concanavalin
      A agglutinated transformed cells with a low, but not those with a high, ATP
      content. Transformed cells with a high ATP content gained agglutinability after
      ATP depletion by inhibitors of the energy-generating systems, and those with a
      low ATP content lost their agglutinability after restoration of a high ATP
      content by glucose. Fixation of the surface membrane by formaldehyde,
      glutaraldehyde, or LaCl(3), inhibited agglutination of cells with an ATP content
      that allows agglutination. Normal fibroblasts grown at a high or a low cell
      density were not agglutinated by concanavalin A. Depletion of the cellular ATP
      content of normal cells induced agglutination only in cells grown at a high, but
      not at a low, cell density. A similar number of concanavalin A molecules was
      bound to the surface membrane of agglutinating and nonagglutinating fibroblasts.
      It is suggested that a high content of ATP inhibits the movement of concanavalin
      A binding sites, and that a low content of ATP allows, in transformed cells, a
      new distribution of binding sites to form the clusters required for cell
      agglutination. Agglutinability of transformed cells is determined by ATP content,
      and in normal cells changes in the content of ATP are by themselves not
      sufficient to induce agglutination. Transformed cells, therefore, do not have a
      control, presumably for membrane stability, that exists in normal cells.

PMID- 4352656
TI  - Induction of lymphocyte transformation by sequential treatment with neuraminidase
      and galactose oxidase.
AB  - Treatment of mouse-spleen cells with galactose oxidase (EC 1.1.3.9) after
      incubation with neuraminidase (EC 3.2.1.18) induced extensive blastogenesis.
      Treatment of the cells with galactose oxidase before incubation with
      neuraminidase had very little stimulatory effect. Either of these enzymes alone
      had practically no effect on the cells. The lymphocyte transformation induced by
      galactose oxidase in neuraminidase-treated cells was decreased upon reacting the
      cells with borohydride or hydroxylamine, whereas treatment with these compounds
      did not affect transformation of cells by concanavalin A. It is suggested that
      galactosyl residues exposed by the action of neuraminidase on the cell membrane
      are oxidized by galactose oxidase, and the aldehyde moiety thus formed is
      involved in the induction of blastogenesis.

PMID- 4352655
TI  - A temperature-sensitive change in the energy of activation of hormone-stimulated
      hepatic adenylyl cyclase.
AB  - We describe an abrupt increase (at 32 degrees ) in the energy of activation for
      the reaction of hepatic adenylyl cyclase in the presence of glucagon or
      epinephrine. This increase is not seen in the presence of fluoride, prostaglandin
      E(1), or 1-propanol, or in the absence of cyclase stimulators. The change in
      energy of activation found with hormones is abolished by 1-propanol. This change
      does not represent differences in hormone or substrate binding at different
      temperatures, but seems to reflect interactions among elements of the cyclase
      stimulation sequence. Similar changes in energy of activation were not observed
      for alkaline phosphatase, cyclic AMP-phosphodiesterase, 5'-nucleotidase, or
      ouabain-sensitive ATPase. Since the mole fraction of cholesterol in liver
      membranes is sufficiently high to preclude a phase change in bulk membrane
      lipids, our observation suggests either that cyclase is restricted to cholesterol
      poor membrane regions or that the change in its energy of activation is largely
      restricted to protein components of the cyclase apparatus. The data are
      compatible with fundamental differences in the stimulation process(es) for the
      hormones (glucagon and epinephrine) as compared with those for fluoride and
      prostaglandin E(1).

PMID- 4352657
TI  - Activation by adenosine 3':5'-monophosphate of a membrane-bound phosphoprotein
      phosphatase from toad bladder.
AB  - Adenosine 3':5'-monophosphate (cyclic AMP) caused a decrease in the net rate of
      incorporation of radioactive phosphate into a specific protein (protein D) in a
      membrane fraction from toad bladder. Moreover, when the membrane protein was
      prelabeled with radioactive phosphate, cyclic AMP caused an increase in the net
      rate of removal of radioactive phosphate from this specific protein. Certain
      agents were shown to be selective inhibitors of membrane-bound protein D kinase
      or protein D phosphatase. With the help of these agents, it was concluded that
      cyclic AMP caused the activation of membrane-bound protein D phosphatase. The
      present data, together with earlier studies, are compatible with the possibility
      that the cyclic AMP-induced activation of a membrane-bound phosphoprotein
      phosphatase in toad bladder, with the consequent dephosphorylation of protein D,
      may be responsible for the physiological effects of antidiuretic hormone on
      sodium and/or water transport in this tissue.

PMID- 4352658
TI  - Spin-state correlations in near infrared spectroscopy of cytochrome c'.
AB  - Characteristic absorption spectra in the ultraviolet, visible, and near infrared
      regions are correlated with spin state in ferriheme proteins. Weak, diffuse bands
      in the near infrared exhibit maxima at about 1000-1100 nm (high spin) and at
      about 1450-1750 nm (low spin). In these and earlier studies such correlations
      have been established for several ferriheme proteins, but less extensively than
      in the more well-known cases of Soret and visible band maxima. We have
      strengthened the correlation in the near infrared by measurements of absorption
      spectra in Rhodospirillum rubrum cytochrome c', a variant c-type cytochrome that
      exhibits a pH-induced transition from high-spin to low-spin state as the pH
      varies from 6.3 to 13.1. Data are provided on extinction coefficients of
      characteristic absorption bands at various pH values, obtained by comparison with
      those measured under the same conditions for horse-heart ferricytochrome c. It is
      concluded that good correlations of spin state with absorption behavior exist
      over the entire spectroscopic range from 250 to 2500 nm and that the basic
      assignments of absorption bands to in-plane charge transfer processes are
      consistent with these correlations.

PMID- 4352659
TI  - Protein kinase activity in erythrocyte ghosts of patients with myotonic muscular
      dystrophy.
AB  - Myotonic muscular dystrophy is a disorder of humans that involves many organ
      systems. Physiological studies have suggested that the fundamental defect is of
      membrane origin. Heretofore, no reproducible metabolic abnormalities have been
      demonstrated. In the present studies we used erythrocyte ghosts as a convenient
      source of purified membranes that do not possess changes of denervation,
      dystrophy, and fibrosis that might complicate the interpretation of muscle
      membrane changes. Our experiments demonstrated a significant difference in the
      phosphorylation of erythrocyte ghost protein by [gamma-(32)P]ATP, with endogenous
      protein kinase of erythrocyte membrane as the enzyme source. After ghosts were
      kept for 1 week at -20 degrees , phosphorylation of membrane protein in eight
      controls was twice as high as endogenous protein kinase activity measured in
      fresh preparations. No stimulation was seen in preparations from seven myotonic
      dystrophy patients from three different families. This reproducible difference in
      normal and myotonic membranes may represent an important new approach to studies
      of this debilitating inborn error of metabolism.

PMID- 4352661
TI  - Glia-induced morphological differentiation in neuroblastoma cells.
AB  - Glial cells release a factor into their culture medium that induces a high degree
      of morphological differentiation in neuroblastoma cells under normal growth
      conditions. This phenomenon is not correlated with a change in intracellular
      adenosine 3':5'-cyclic monophosphate or in the rate of cell growth. Media from
      other cell lines tested induce less morphological differentiation or have no
      effect.

PMID- 4352660
TI  - Common cell-surface antigen associated with murine and feline C-type RNA leukemia
      viruses.
AB  - A new common cell-surface antigen associated with murine and feline C-type RNA
      leukemia viruses was demonstrated by the use of rabbit antiserum against feline
      leukemia virus and the indirect membrane immunofluorescence test. Common cell
      surface antigen was found in all leukemias of all strains of mice tested, in
      normal lymphoid tissues of Gross-positive (high incidence of leukemia) mouse
      strains AKR, AKR.H-2(b), C58, and NZB, in cultured rat fibroblasts infected with
      Rauscher virus, in cultured feline fibroblasts infected with feline leukemia
      virus, and in spontaneous feline lymphosarcoma. The antigen was not demonstrable
      in normal adult and fetal tissues of Gross-negative mouse strains or in tissues
      and cultured fibroblasts derived from normal rats and normal cats. The
      immunoferritin study of murine leukemia cells revealed that the antigen was
      located on the cell surface in discrete areas; budding and C-type RNA viral
      envelope was not labeled as antigen site. The distribution of common cell-surface
      antigen on murine and feline leukemias, as well as on normal lymphoid tissues of
      Gross-positive mouse strains, indicates the presence of an antigen distinct from
      any cell-surface antigen heretofore shown to be associated with, or specified by,
      mammalian C-type RNA viruses.

PMID- 4352662
TI  - Primary carcinomas of the liver in Hong Kong: some possible aetiological factors.

PMID- 4352663
TI  - Detection and assessment of case clustering in Burkitt's lymphoma and Hodgkin's
      disease.

PMID- 4352664
TI  - Epidemiologic and immunologic considerations on the pathogenesis of Burkitt's
      Tumor.

PMID- 4352665
TI  - Etiology of Burkitt's lymphoma.

PMID- 4352666
TI  - Multiplicity of lung tumour classifications.

PMID- 4352667
TI  - Investigation on the epidemiological significance of detailed cancer data-
      preliminary results.

PMID- 4352669
TI  - [Resorption of iodized oil labeled with I-125 in intramuscular administration in
      rats].

PMID- 4352668
TI  - Histoenzymologic and biochemical investigations into the nervous tissue round an
      experimentally-induced cerebral hemorrhagic focus.

PMID- 4352670
TI  - Plasma lipoproteins and hyperlipoproteinemia.

PMID- 4352671
TI  - Comparative metabolic and clinical studies of sexual ateliotic dwarfs and
      diabetics.

PMID- 4352672
TI  - Ophthalmoscopic findings and changes in hormonal and metabolic parameters in
      "protodiabetes".

PMID- 4352673
TI  - Kidney structural abnormalities in early diabetes.

PMID- 4352674
TI  - Ultrastructural pathology of periperal nervous system in early diabetes.

PMID- 4352675
TI  - Neurological findings in chemical diabetes.

PMID- 4352676
TI  - Neurological changes in early diabetes.

PMID- 4352677
TI  - Clinical features of peripheral neuropathy associated with hypoglycemia.

PMID- 4352679
TI  - Lymphography and patients' reactions.

PMID- 4352678
TI  - Malakoplakia of the skin: report of a case.

PMID- 4352680
TI  - Initial psychological research related to the Occupational Safety and Health Act
      of 1970.

PMID- 4352682
TI  - [Physiological significance of prostaglandins].

PMID- 4352681
TI  - Anesthetic effects on cerebral metabolism.

PMID- 4352684
TI  - [Physiology and metabolism of cholecalciferol].

PMID- 4352683
TI  - [Prostaglandins, blood platelets, and thrombosis].

PMID- 4352686
TI  - Electroretinogram and afferent visual transmission in the epileptic baboon Papio
      papio. Effects of drugs influencing monoaminergic systems.

PMID- 4352685
TI  - Treatment of infantile spasms and Lennox-Gastaut syndrome with clonazepam
      (Rivotril).

PMID- 4352687
TI  - Preparation and purification of a structural sialofucoglycoprotein from the
      bovine lens capsule.

PMID- 4352688
TI  - Lens polyol dehydrogenase.

PMID- 4352689
TI  - Morphology and biological properties of transplantable tumours induced by polyoma
      virus.

PMID- 4352690
TI  - Relationships among pollution indicator bacteria isolated from raw water and
      distribution systems by the presence-absence (P-A) test.

PMID- 4352691
TI  - Effect of anaerobiosis on respiratory rate, cytochrome oxidase activity and
      mitochondrial structures in coleoptiles of rice (Oryza sativa L.).

PMID- 4352692
TI  - Studies on contract inhibition of growth in the mouse fibroblast, 3T3. I. Changes
      in cell size and composition during 'unrestricted' growth.

PMID- 4352693
TI  - Studies on contact inhibition of growth in the mouse fibroblast, 3T3. II. Effects
      of amino acid deprivation and serum on growth rate.

PMID- 4352694
TI  - Relapsing peripheral neuropathy in association with renal carcinoma.

PMID- 4352695
TI  - The future of medical practice.

PMID- 4352696
TI  - [Active vasomotor reactions of the coronary vessels during the action of certain
      humoral stimuli].

PMID- 4352697
TI  - [Effect of antidotal therapy on the functional state of the cardiovascular system
      in chronic mercury poisoning].

PMID- 4352698
TI  - [Effect of preliminary adaptation to physical load on the state of the myocardium
      in experimental heart defect].

PMID- 4352699
TI  - Purification of oestradiol receptors by affinity chromatography.

PMID- 4352700
TI  - Genetic origin of RD114 and other RNA tumour viruses assayed by molecular
      hybridization.

PMID- 4352701
TI  - Extensive homology of RD114 virus DNA with RNA of feline cell origin.

PMID- 4352702
TI  - Partial characterization of RD114 virus by DNA-RNA hybridization studies.

PMID- 4352703
TI  - Measurement of RD114 virus nucleotide sequences in feline cellular DNA.

PMID- 4352704
TI  - [Correlation between laboratory evaluation of vaccines in animals and reactions
      to vaccination and serologic response in children vaccinated against pertussis].

PMID- 4352705
TI  - [Japanese B encephalitis].

PMID- 4352706
TI  - [Hydatidiform mole in a clinical material covering a 10-year period].

PMID- 4352707
TI  - A practitioner's experiences with adenoviral infection in Arabian foals.

PMID- 4352708
TI  - [Use of sorbents of natural origin for the treatment of internal radiocesium
      contamination in pigs].

PMID- 4352709
TI  - Intensification of hypertriglyceridemia by either alcohol or carbohydrate.

PMID- 4352710
TI  - Absorption of fortification iron in bread.

PMID- 4352711
TI  - Cyclic AMP in digestive physiology.

PMID- 4352712
TI  - Evaluation of live-virus vaccine against avian encephalomyelitis in turkey
      breeder hens.

PMID- 4352713
TI  - Ultrastructural comparison of morphogenesis and fate of Marek's disease and
      infectious laryngotracheitis viruses in chicken kidney cells.

PMID- 4352714
TI  - A polymer of N-acetylglucosamine 1-phosphate in the wall of Staphylococcus lactis
      2102.
AB  - 1. Walls of Staphylococcus lactis 2102 contain about 40% of a phosphorylated
      polysaccharide, which was isolated by extraction with cold trichloroacetic acid,
      with dilute NaOH, and also by digestion with a Flavobacterium peptidase. 2. The
      purified polymer contained equimolar proportions of N-acetylglucosamine and
      phosphate as its sole constituents and was readily hydrolysed under gentle acidic
      conditions to N-acetylglucosamine 6-phosphate. 3. Studies on the intact polymer
      showed that it is linear and that adjacent acetamido sugar units are joined by
      phosphodiester bonds between their 1- and 6-positions, the glycosidic linkages
      having the alpha-configuration. This polymer is thus the simplest of the known
      microbial wall polymers possessing sugar 1-phosphate linkages. 4. Alkali
      degradation of the extracted polymer proceeds predominantly in a stepwise manner
      from the reducing end, but evidence was obtained for the direct hydrolysis of
      some of the inter-unit phosphodiester groups.

PMID- 4352715
TI  - Isolation and characterization of C1q, a subcomponent of the first component of
      complement, from human and rabbit sera.
AB  - 1. C1q, a subcomponent of the first component of complement, has been isolated,
      in a haemolytically active and soluble form, by ion-exchange chromatography and
      gel filtration, from human and rabbit sera. Yields ranged from 10 to 25mg/litre
      of serum and the activity of final preparations was consistently in the range
      5x10(3)-15x10(3) C1qH(50) units/mg. 2. The molecular weights of human and rabbit
      subcomponent C1q were 409600 and 417600, as determined by sedimentation
      equilibrium studies. 3. Subcomponent C1q from both species was shown to be
      composed of non-covalently linked subunits of approximately 57000 molecular
      weight as determined by gel-filtration or sedimentation equilibrium studies in
      5.3m-guanidinium chloride. Reduction or oxidation of human and rabbit
      subcomponent C1q yielded three chains each having a molecular weight of
      approximately 23000 and which differed slightly in amino acid composition but
      markedly in carbohydrate content. The oxidized chains were separated, on a
      preparative scale, by ion-exchange chromatography in 8m-urea on DEAE-cellulose.
      4. Both human and rabbit subcomponent C1q contained hydroxyproline,
      hydroxylysine, a high percentage of glycine and approximately 8% carbohydrate.
      Glutamic acid and aspartic acid were the free N-terminal amino acids of human
      subcomponent C1q whereas only serine was found in rabbit subcomponent C1q. 5.
      Collagenase digestion of human or rabbit subcomponent C1q caused a rapid loss of
      haemolytic activity which correlated with the breakdown of collagenous regions in
      the molecule.

PMID- 4352716
TI  - Anthranilate synthase-anthranilate 5-phosphoribosyl 1-pyrophosphate
      phosphoribosyltransferase from Aerobacter aerogenes.
AB  - 1. Anthranilate synthase and phosphoribosyltransferase from Aerobacter aerogenes
      purify simultaneously and sediment together on sucrose gradients, showing that
      they occur as an enzyme aggregate. Both activities of the intact aggregate are
      subject to inhibition by tryptophan. 2. By using appropriate auxotrophic mutants
      it was shown that an intact active enzyme aggregate is formed when the components
      come from separate mutant strains. An intact active aggregate can also be formed
      when one component is from Escherichia coli and the other from A. aerogenes. 3.
      Phosphoribosyltransferase of A. aerogenes is active when not in an aggregate with
      anthranilate synthase, but is not subject to tryptophan inhibition, indicating
      that the inhibitor site is on the anthranilate synthase component. 4.
      Anthranilate synthase can be active and sensitive to tryptophan inhibition when
      complexed with an inactive phosphoribosyltransferase. 5. Kinetic studies on the
      anthranilate synthase activity show that tryptophan is a competitive inhibitor
      with respect to chorismate and a non-competitive inhibitor with respect to either
      glutamine or NH(4) (+) ions. This is consistent with a sequential mechanism of
      the ordered type in which chorismate is the first reactant.

PMID- 4352717
TI  - A membrane-bound activity catalysing phosphatidylinositol breakdown to 1,2
      diacylglycerol, D-myoinositol 1:2-cyclic phosphate an D-myoinositol 1-phosphate.
      Properties and subcellular distribution in rat cerebral cortex.
AB  - 1. Breakdown of phosphatidylinositol was studied in homogenates and subcellular
      fractions of rat cerebral cortex by using both membrane-bound and externally
      added [(32)P]phosphatidylinositol as substrate. 2. In the presence of
      deoxycholate breakdown followed first-order kinetics at low substrate
      concentrations ([unk]1mm) and zero-order kinetics at higher concentrations (6
      9mm). 3. Maximum breakdown by cerebral-cortex homogenates was approximately
      0.5mumol/h per mg of protein and occurred at pH7.0 in the presence of 8mm
      phosphatidylinositol, 2mm-CaCl(2) and 2mg of deoxycholate/ml. Activity was
      abolished by 1mm-ethanedioxybis(ethylamine)tetra-acetate. 4. The products of
      phosphatidylinositol breakdown were 1,2-diacylglycerol and a mixture of d
      myoinositol 1:2-cyclic phosphate (55%) and d-myoinositol 1-phosphate (45%). The
      two phosphate esters appeared to be produced together and in constant
      proportions. 5. Some 51% of the activity was particle-bound, with the highest
      activities in small nerve endings, microsomal material and two synaptic membrane
      fractions (fractions Mic(20), Mic(100), M(1) 1.0 and M(1) 0.9 respectively), all
      of which were also rich in acetylcholinesterase and which have been shown to be
      rich in other surface-membrane enzymes. Much of the particle-bound activity
      therefore appears to be present in cerebral-cortex plasma membranes. 6. The
      results are discussed in relation to previously described soluble activities that
      catalyse the same reaction, and to a possible role of the membrane-bound enzyme
      in enhanced phosphatidylinositol turnover in externally stimulated cells.

PMID- 4352718
TI  - The amino acid sequences of cytochromes c-551 from three species of Pseudomonas.
AB  - The amino acid sequences of the cytochromes c-551 from three species of
      Pseudomonas have been determined. Each resembles the protein from Pseudomonas
      strain P6009 (now known to be Pseudomonas aeruginosa, not Pseudomonas
      fluorescens) in containing 82 amino acids in a single peptide chain, with a haem
      group covalently attached to cysteine residues 12 and 15. In all four sequences
      43 residues are identical. Although by bacteriological criteria the organisms are
      closely related, the differences between pairs of sequences range from 22% to
      39%. These values should be compared with the differences in the sequence of
      mitochondrial cytochrome c between mammals and amphibians (about 18%) or between
      mammals and insects (about 33%). Detailed evidence for the amino acid sequences
      of the proteins has been deposited as Supplementary Publication SUP 50015 at the
      National Lending Library for Science and Technology, Boston Spa, Yorks. LS23 7BQ,
      U.K., from whom copies can be obtained on the terms indicated in Biochem. J.
      (1973), 131, 5.

PMID- 4352719
TI  - The nature of polydisperse ribonucleic acid in plants.
AB  - The aggregation of ribosomal RNA species during chromatography on methylated
      albumin on kieselguhr was decreased from 50 to 15% by the lower salt
      concentrations made possible by the use of higher pH values. The polydisperse RNA
      was resolved into two fractions. About 50% was eluted with the rRNA whereas the
      remainder was bound to the column, and was recovered only by solubilization of
      the methylated albumin. Both fractions of polydisperse RNA were similar in size
      range, but the bound fraction was considerably richer in AMP. No D-RNA (DNA-like
      RNA) peak was resolved under these conditions of column fractionation. However,
      the properties of the bound RNA were consistent with it containing both D-RNA and
      TB-RNA (tenaciously bound RNA). The relationship between these two fractions of
      AMP-rich RNA was considered. The bound RNA and ribosomal RNA responded
      differently to various treatments. The salt concentration required to elute
      ribosomal RNA was halved by increasing the pH of the fractionation, but the
      amount of bound RNA was in fact increased. Denaturation by hot urea decreased the
      binding of ribosomal RNA to the methylated albumin, but did not facilitate
      elution of bound RNA. The high affinity between the AMP-rich polydisperse RNA and
      the methylated albumin does not therefore appear to arise for the secondary
      structure conferred by the high AMP content.

PMID- 4352720
TI  - Nucleotide sequence analysis with polynucleotide kinase and nucleotide "mapping"
      methods. 5'-Terminal sequences of deoxyribonucleic acid from bacteriophages
      lambda and 424.
AB  - The polynucleotide kinase reaction was used in analyses of complex mixtures of
      oligodeoxynucleotides which were fractionated by various two-dimensional
      nucleotide ;mapping' procedures. Parallel ionophoretic analyses on DEAE-cellulose
      paper, pH2, and AE-cellulose paper, pH3.5, of venom phosphodiesterase partial
      digests of 5'-terminally labelled oligonucleotides enabled the sequence of the
      nucleotides to be deduced uniquely. A ;diagonal ionophoresis' method has been
      used with mixtures of nucleotides. Application of these methods to 5'-terminally
      labelled DNA from bacteriophage lambda gave the terminal sequences pA-G-G-T-C-G
      and pG-G-G-C-G. Identical 5'-terminal sequences were found with DNA from
      bacteriophage 424.

PMID- 4352723
TI  - The effects of supplements varying in carotene and calcium content on the
      physical, biochemical and skeletal status of preschool children.

PMID- 4352722
TI  - Iron metabolism in the veal calf. 2. Iron requirements and the effect of copper
      supplementation.

PMID- 4352724
TI  - Site of latent herpes.

PMID- 4352721
TI  - A sequence of seventy-three nucleotides from the coliphage R17 genome.
AB  - 1. A sequence of 73 nucleotides of the RNA genome from coliphage R17 was
      determined. It can be read through in only one translational frame. The fragment
      is not part of the coatprotein cistron (Min Jou et al., 1972), nor does it come
      from the untranslated sequences described previously (Steitz, 1969; Nichols,
      1970; Cory et al., 1970; de Wachter et al., 1971; Contreras et al., 1971; Cory et
      al., 1972). It contains two sequences of 23 and 24 nucleotides, 22 of which are
      identical. This kind of reiteration is the first one found in bacteriophage
      nucleic acid. 2. Improved conditions were found and tested for blocking
      oligonucleotides with carbodi-imide and cleaving by ribonuclease A at cytidylate
      residues. 3. A synthetic medium is described which allows labelling in vivo with
      (32)P to give specific radioactivities higher than those obtained in the
      procedures used previously.

PMID- 4352725
TI  - Infantile herpes zoster after intrauterine exposure to varicella.

PMID- 4352726
TI  - Beclomethasone dipropionate steriod aerosol in treatment of perennial allergic
      asthma in children.
AB  - Thirty-one chronic perennial asthmatics aged from 2(1/2) to 16 years were treated
      with beclomethasone dipropionate pressurized aerosols for up to 20 months. Of
      these, 16 patients dependent on oral corticosteroid or corticotrophin for up to
      11 years were successfully transferred to this treatment, with one exception.
      Steroid withdrawal symptoms were slight. Loss of weight, disappearance of
      Cushingoid features, and resumption of growth indicated lack of systemic side
      effects. Fifteen others inadequately controlled on bronchodilators or disodium
      cromoglycate, were also effectively treated, and no clinical evidence of adrenal
      suppression was noted.

PMID- 4352727
TI  - Inhibitory interaction between X and Y units in the cat lateral geniculate
      nucleus.

PMID- 4352728
TI  - A cholinergic inhibitory system in the frog optic tectum: its role in visual
      electrical responses and feeding behavior.

PMID- 4352729
TI  - [Analysis of the effects of learning and the level of acquisition on consecutive
      paradoxical sleep].

PMID- 4352730
TI  - Synaptogenesis and the development of neurotransmitter enzymes in organotypic
      cultures of chick spinal cord.

PMID- 4352731
TI  - Characterization of central angiotensin II receptors involved in the elicitation
      of drinking in the rat.

PMID- 4352732
TI  - Tetanus toxin blocks the efferent endings in the cochlea.

PMID- 4352733
TI  - d-Tubocurarine does not antagonize the inhibitory effects of GABA at the
      crustacean neuromuscular junction.

PMID- 4352734
TI  - Antagonism of neuronal excitation by 1-hydroxy-3-aminopyrrolidone-2.

PMID- 4352735
TI  - Comparison of effects of noradrenaline and histamine with cyclic AMP on brain
      stem neurones.

PMID- 4352736
TI  - Effects of intracerebral injections of 5,6-dihydroxytryptamine on central
      monoamine neurons: evidence for selective degeneration of central 5
      hydroxytryptamine neurons.

PMID- 4352737
TI  - Effect of two ACTH-analogs on noradrenaline metabolism in rat brain.

PMID- 4352738
TI  - Cytosol-modulated transport of messenger RNA from isolated nuclei.

PMID- 4352739
TI  - A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross
      linking agents.

PMID- 4352740
TI  - Anemia virus as a distinct component of the murine leukemia-sarcoma complex of
      viruses.

PMID- 4352741
TI  - Cholesterol metabolism in rats bearing Morris hepatoma 7777.

PMID- 4352742
TI  - Modification of hexosaminidase isozymes in rat hepatoma.

PMID- 4352743
TI  - Glucagon and prostaglandin E1 stimulation of cyclic adenosine 3', 5'
      monophosphate levels and adenylate cyclase activity in benign hyperplastic
      nodules and malignant hepatomas of ethionine-treated rats.

PMID- 4352744
TI  - Development of an analytical system based around a miniature fast analyzer.

PMID- 4352746
TI  - Herpesvirus saimiri: experimental infection of squirrel monkeys (Saimir
      sciureus).

PMID- 4352745
TI  - Viral investigations in ulcerative colitis and regional enteritis.

PMID- 4352747
TI  - Tumorigenicity assays in nonhuman primates treated with antithymocyte globulin.

PMID- 4352748
TI  - Effects of the antifertility drug enovid in five strains of mice, with particular
      regard to carcinogenesis.

PMID- 4352749
TI  - C-type virus particles in placentas and fetal tissues of Rhesus monkeys.

PMID- 4352750
TI  - Inhibition of human rhabdomyosarcoma-cell growth in agar by dibutyryl cyclic AMP.

PMID- 4352751
TI  - Rejection of polyoma virus-induced neoplasms in mice inoculated with complement
      and antiserum.

PMID- 4352752
TI  - Blastogenic transformation assay for detection of immunologic reactivity to avian
      oncornaviruses.

PMID- 4352753
TI  - Antibodies associated with Epstein-Barr virus in Burkitt's lymphoma during
      injections of BCG or irradiated autochthonous tumor cells.

PMID- 4352754
TI  - Relationship between nuclear pockets in bovine peripheral blood lymphocytes and C
      type virus particles in cultures of these cells.

PMID- 4352755
TI  - Lymphosarcomas in two gibbons (Hylobates lar) with associated C-type virus.

PMID- 4352756
TI  - Amino acid distribution in the nervous system of the crab, Carcinus maenas (L.).

PMID- 4352758
TI  - Accumulation of adenosine 3', 5'-monophosphate in incubated slices from discrete
      regions of squirrel monkey cerebral cortex: effect of norepinephrine, serotonin
      and adenosine.

PMID- 4352757
TI  - Effects of acetylcholine on the incorporation of (32P)orthophosphate in vitro
      into the phospholipids of subsynaptosomal, membranes from guinea-pig brain.

PMID- 4352760
TI  - Metastasising chondroid syringoma.

PMID- 4352759
TI  - Enzymatic regulation of adenosine 3',5'-monophosphate (cyclic AMP) in the
      freezing epileptogenic lesion of rat brain and in homologous contralateral
      cortex.

PMID- 4352761
TI  - Histologically benign mixed parotid tumour with hepatic metastasis.

PMID- 4352762
TI  - Auto-antibodies in acute viral hepatitis, yellow fever, and hepatocellular
      carcinoma: clinical and experimental findings.

PMID- 4352763
TI  - Pigmented progonoma in a dermoid cyst of the ovary.

PMID- 4352764
TI  - The effect of isoprenaline on cyclic AMP concentrations in skeletal muscle.

PMID- 4352765
TI  - An inhibition of post-ganglionic motor transmission in the mammalian vas deferens
      by D-lysergic acid diethylamide.
AB  - 1. Under certain conditions D-lysergic acid diethylamide (LSD), 10(-9)-10(-6)
      g/ml., exerted an immediate, prolonged and slowly reversible inhibitory effect
      upon the post-ganglionic motor transmission in desheathed guinea-pig vas deferens
      preparations.2. The most critical factor influencing this action of LSD appeared
      to be the train length. With short trains of less than 4 or 5 pulses the twitch
      inhibition produced by LSD was often total. With longer trains (5-20 pulses), the
      degree of inhibition declined with increase in train length. These results
      suggest the existence of two components in the motor response to post-ganglionic
      stimulation, distinguished by their susceptibility to LSD.3. The inhibition of
      the LSD-susceptible component was related to the dose of LSD in the range 10(-9)
      10(-6) g/ml., reaching a maximum at 0.5-1 x 10(-6) g/ml. The response remnants
      elicited by trains of more than 5 pulses under these conditions could not be
      reduced further by a ten- to twenty-fold increase in LSD concentration to 10(-5)
      g/ml. and were in fact slightly potentiated.4. The inhibition of post-ganglionic
      motor transmission by LSD was not explicable on the basis of an alpha
      adrenoceptor blockade because it was not associated with any reduction in motor
      responses to noradrenaline.5. The use of propranolol excluded mediation of the
      LSD-inhibition by beta-adrenoceptors.6. The LSD effect was not due to a non
      specific smooth muscle depression because it was not associated with any
      reduction in motor responses to acetylcholine, ATP or bradykinin.7. The
      inhibitory effect of LSD on post-ganglionic transmission resembled that of
      noradrenaline in that it was antagonized by phentolamine; another alpha
      adrenoceptor blocking agent, phenoxybenzamine, was less effective than
      phentolamine in this respect.8. The LSD-inhibition was obtained in preparations
      taken from reserpinized guinea-pigs.9. The inhibition of motor transmission in
      the vas deferens by LSD was confirmed in rats, Meriones shawii and rabbits.10.
      The inhibition of post-ganglionic transmission by LSD was unrelated to its
      ability to antagonize 5-hydroxytryptamine (5-HT), to which the longitudinal
      muscle of the guinea-pig vas deferens is insensitive. The more potent 5-HT
      antagonists, methysergide and BOL 148 were either virtually inactive or
      considerably weaker than LSD.

PMID- 4352768
TI  - The effect of procaine hydrochloride and insulin on the cyclic AMP mediated
      responses in rat adipose tissue.

PMID- 4352767
TI  - Effects of membrane depolarization on light scattering by cerebral cortical
      slices.
AB  - 1. A system is described for simultaneously measuring the respiration and the
      reflectance of a tissue slice and is applied to a study of guinea-pig cerebral
      cortical slices.2. Reducing bathing medium osmolarity led to a reversible
      decrease in reflectance of these slices (as well as slices from liver and kidney
      cortex). In half isotonic solutions reflectance was reduced by 31%.3. Anoxia led
      to a decreased reflectance which was eliminated if all the Cl was substituted by
      the larger glucuronate anion.4. It is concluded that slice reflectance is lowered
      when cellular volumes are increased by water or isotonic solution influx.5.
      Membrane depolarization effected by ouabain, high (60 mM) K bathing medium,
      veratridine or repeated electrical pulses led to rapid decreases in reflectance
      of 25, 27, 31 and 7.5% respectively. Turning off the electrical pulses caused
      reflectance to return to control values. Reversibility of the chemical effectors
      was not tested.6. Substitution of Cl by glucuronate abolished the reflectance
      changes, although it did not inhibit the increased respiration induced by the
      depolarizing stimuli.7. Tetrodotoxin abolished both the respiratory and
      reflectance effects of veratridine and electrical pulses but had no effect upon
      those of high K or ouabain.8. The decrease in reflectance began about 1 sec after
      initiation of the pulses and was half maximal by 8 sec.9. Titrating reflectance
      against [K] showed that an increase of 5 mM-K led to a 4% decrease in reflectance
      and that reflectance became minimal between 60 and 80 mM-K(+).10. It is concluded
      that membrane depolarization in excitable cells of the cerebral cortex (and also,
      possibly, in the glia) causes rapid increases in cell volume due to influx of
      isotonic solution.11. The results indicate, more specifically, that changes in
      intercellular K concentrations of size and duration thought to occur following
      nervous activity in the C.N.S. cause cell volume changes large enough to
      drastically reduce the intercellular volumes and so, transiently, increase
      extracellular molecular and ionic concentrations. Increases of extracellular [K]
      and [Ca] have significant effects upon synaptic transmission and upon spontaneous
      nervous activity. It is suggested that nervous activity in one cell (or portion
      of it) might, in this way, strongly influence function in neighbouring elements.

PMID- 4352766
TI  - Pancreatic acinar cells: ionic dependence of the membrane potential and
      acetycholine-induced depolarization.
AB  - 1. Intracellular recordings of membrane potentials have been made in vitro from
      the exocrine acinar cells of the mouse pancreas using glass micro-electrodes.2.
      The mean membrane potential of the acinar cells during superfusion with Krebs
      Henseleit solution was -39.2 mV. Increasing [K](o) tenfold decreased the membrane
      potential by 28 mV when [K](o) was above 10 mM. This depolarization was not
      affected by atropine (1.4 x 10(-6)M). Strophanthin-G (10(-3)M) slowly depolarized
      the cells at about 10 mV hr(-1).3. Brief exposure to acetylcholine (ACh), 5.5 x
      10(-5)M, or pancreozymin resulted in a short lasting depolarization of the acinar
      cells. Atropine (1.4 x 10(-6)M) blocked the depolarizing action of ACh but not
      that of pancreozymin. Adrenaline (5.5 x 10(-5)M) or cyclic AMP (10(-3)-10(-4)M)
      did not influence the membrane potential.4. The amplitude of the ACh-induced
      depolarization was not dependent on the presence of CO(2)/HCO(3) in the bathing
      fluid, but it was closely dependent on the extracellular Na concentration.
      However, ACh was still able to evoke a small depolarization even after prolonged
      exposure of the tissue to a Na-free solution.5. During exposure of the tissue to
      a Ca-free solution the resting membrane potential was decreased and the ACh
      induced depolarization was significantly reduced. Some substances which are known
      in other tissues to inhibit membrane Ca(2+) currents, i.e. La(3+), D-600 and
      tetracaine, were able to reduce, but never abolish, the ACh-induced
      depolarization.6. These results suggest that the effect of ACh on the pancreatic
      acinar cell is to increase the permeability of the membrane to commonly occurring
      ions with a consequent Na-influx and a small Ca-influx.

PMID- 4352769
TI  - In vitro production of apolipoproteins in rat liver slices.

PMID- 4352770
TI  - The rabbit rectococcygeus, a smooth muscle preparation with an atropine
      susceptible cholinergic motor transmission.

PMID- 4352771
TI  - Adenoid cystic carcinoma of the trachea. Response to colbalt-60.

PMID- 4352773
TI  - [Gradual synthesis of oligonucleotides. The specificity of the synthetic function
      of Penicillium brevicompactum RNAase and the structure of the phosphate donor].

PMID- 4352772
TI  - Carcinoembryonic antigen in patients with carcinoma of the lung.

PMID- 4352774
TI  - [Gradual synthesis of oligonucleotides. The specificity of the synthetic function
      of Penicillium brevicompactum ribonuclease and the structure of the phosphate
      acceptor].

PMID- 4352776
TI  - The dependence of thoracic surgery on radiology.

PMID- 4352775
TI  - Management of the acute burn patient--1973.

PMID- 4352777
TI  - Virus-induced cholesterol crystals.
AB  - One of the crystal types induced in cell cultures by a new feline herpesvirus was
      identified as cholesterol by crystal structure, polarized light microscopy, and
      mass spectroscopy.

PMID- 4352778
TI  - Neurologic findings in retroperitoneal mass lesions.

PMID- 4352779
TI  - [On the problem of emergency supply with drinking water by way of a Seitz
      filter].

PMID- 4352780
TI  - [The therapeutic efficacy of human leukocyte interferon in the treatment of viral
      diseases of the genitalia].

PMID- 4352781
TI  - [Cytochrome oxidase histochemistry in cilioepithelial cystomas undergoing
      malignant change].

PMID- 4352782
TI  - Pseudomonas endocarditis.

PMID- 4352783
TI  - Pancreatic islet cell carcinoma. I. Clinical features of 52 patients.

PMID- 4352784
TI  - Pancreatic islet cell carcinoma. II. Results of therapy with streptozotocin in 52
      patients.

PMID- 4352785
TI  - Segmental renal-vein renin sampling for segmental renal infarction. Studies in a
      hypertensive patient.

PMID- 4352786
TI  - Viral disease of the labyrinth. II. An experimental model using mouse
      cytomegalovirus.

PMID- 4352787
TI  - Optic neuropathy of Graves disease, hyperthyroidism, and ocular myasthenia
      gravis.

PMID- 4352788
TI  - Demonstration of a glucocorticoid hormone-receptor complex in the cytoplasm of a
      hormone-responsive tumour.
AB  - Specific substances binding [(3)H]-triamcinolone acetonide have been demonstrated
      in the cytoplasmic fraction of the R3230AC mammary carcinoma using sucrose
      gradient centrifugation. These receptors, which exhibit sedimentation
      coefficients of 8-9 Svedberg units, are relatively specific for glucocorticoid
      ligands and possess a high affinity for triamcinolone acetonide (K(d)~7 * 10(-8)
      mol/1).

PMID- 4352789
TI  - The induction of tumours in the guinea-pig with methylcholanthrene and
      diethylnitrosamine and their propagation in vivo and in vitro.
AB  - Tumour induction with diethylnitrosamine (DEN) and methylcholanthrene (MCA) has
      been studied in 3 strains of guinea-pig. A DEN concentration of 80 MUg/ml
      drinking water daily proved too toxic but reasonable survival was obtained with
      20 MUg/ml 3 times per week in Hartley guinea-pigs and a local inbred strain.
      Heston Strain 13 guinea-pigs were particularly susceptible to the toxic effects
      of the diethylnitrosamine. In all3strains, 100% of the animals which survived the
      early toxic effects subsequently developed hepatomata, the mean time being 15
      months. Methylcholanthrene was less toxic but more erratic as a carcinogen, the
      incidence of tumours in Hartley guinea-pigs varying from 18 to 100% in different
      experiments, the mean time of tumour development being 10 months.Three
      transplantable hepatomata and 3 transplantable sarcomata have been developed. The
      hepatomata are all predominantly hepatocellular carcinomata and the sarcomata
      comprise two liposarcomata and a fibrosarcoma. Successful shortterm primary
      cultures of hepatomata, sarcomata and of normal liver tissues have been
      accomplished. Established cell lines in tissue culture have been developed from
      one cholangiocarcinoma from an outbred guinea-pig and one transplanted
      hepatocellular carcinoma from an inbred guinea-pig.

PMID- 4352790
TI  - Increased carcinogenic action of dimethylnitrosamine after prior administration
      of carbon tetrachloride.
AB  - Rats were given a single dose of dimethylnitrosamine (DMN, 20 mg/kg body weight)
      alone or 42 or 60 hours after a non-lethal hepatotoxic dose of carbon
      tetrachloride (CC1(4)) and killed 12 months later. DMN alone produced no tumours
      in the kidney and a few in the liver, but when given 42 hours after CC1(4),
      tumours formed in the kidneys and the number in the liver was increased. When
      given after 60 hours, the incidence of kidney tumours was less but that of liver
      tumours was further increased. A larger dose of DMN (40 mg/kg) was tolerated 42
      hours after CC1(4) and enhanced the number of kidney and liver tumours, the
      latter apparently due to an increased proportion of cholangiomata. Numerous small
      focal proliferations of atypical liver cells and of bile duct epithelium were
      observed after treatment with DMN. The incidence of these lesions in the
      different experimental treatments varied in a similar manner to the liver
      tumours.

PMID- 4352791
TI  - Inhibition of malignant cell invasion in vitro by a proteinase inhibitor.
AB  - The inhibitory effect of the protease inhibitor aprotinin (Trasylol) on the
      invasion of mouse kidney explants by polyoma virus transformed BHK21 cells was
      investigated using a mixed cell/organ culture technique. The extent of invasion
      was monitored by following the changes in LDH isoenzyme pattern in the explants
      and by histological assessment. The kidney explants containing aprotinin were
      found to maintain a normal kidney LDH pattern and to suffer considerably less
      invasion than the explants not containing the drug. These results support the
      idea that proteolytic enzymes are associated with invasion and that inhibitors of
      protease activity could possibly be useful in the management of clinical cancer.

PMID- 4352792
TI  - Cystathionine excess in children with hepatic cancer.

PMID- 4352793
TI  - Age- and sex-associated diethylnitrosamine dealkylation activity of the mouse
      liver and hepatocarcinogenesis.

PMID- 4352794
TI  - Structural and functional changes in Novikoff hepatoma mitochondria.

PMID- 4352796
TI  - Carcinogenesis by urethan via mother's milk and its enhancement of transplacental
      carcinogenesis in mice.

PMID- 4352795
TI  - Competitive RNA-DNA hybridization of nuclear and microsomal RNA during
      diethylnitrosamine hepatocarcinogenesis.

PMID- 4352797
TI  - The metabolism and binding of testosterone in androgen-dependent and autonomous
      transplantable mouse mammary tumors.

PMID- 4352798
TI  - Fine structure of primary liver tumors and tumor-bearing livers in man.

PMID- 4352799
TI  - Specific antigens in human alveolar cell carcinoma.

PMID- 4352800
TI  - Further observations on the effects of trypsin on the volume and functions of
      mitochondria isolated from normal liver and AH-130 Yoshida ascites hepatoma.

PMID- 4352801
TI  - Modification of rabbit adrenal steroid biosynthesis by prolonged ACTH
      administration.

PMID- 4352803
TI  - Reversible inhibition of ACTH-induced corticosteroid release by cycloheximide:
      evidence for an unidentified cellular messenger.

PMID- 4352802
TI  - Adrenocortical control of catecholamine metabolism in the dog adrenal medulla:
      relationship to protein synthesis.

PMID- 4352804
TI  - Dynamics of insulin release by perfused rat pancreases: effects of
      hypophysectomy, growth hormone, adrenocorticotropic hormone, and hydrocortisone.

PMID- 4352805
TI  - Thyrotropin releasing hormone (TRH): neurotransmitter regulation of secretion by
      mouse hypothalamic tissue in vitro.

PMID- 4352806
TI  - Indomethacin, lipolysis, and cyclic AMP accumulation in white fat cells.

PMID- 4352807
TI  - Regulation of steroidogenesis by ACTH in a superfusion system for isolated
      adrenal cells.

PMID- 4352808
TI  - Nuclear receptor estrogen complex: accumulation, retention and localization in
      the hypothalamus and pituitary.

PMID- 4352809
TI  - Vitamin D and intestinal transport of calcium: effects of prednisolone.

PMID- 4352810
TI  - The gonadotropin-primed rat: a model for testing agents that influence steroid
      biosynthesis.

PMID- 4352811
TI  - Effects of estrogens on renin substrate and uterine weights in rats.

PMID- 4352813
TI  - Desquamative interstitial pneumonia: progression to the end-stage lung and the
      unusual complication of alveolar cell carcinoma: case report.

PMID- 4352812
TI  - The chest roentgenogram in babies of 1000 grams or less.

PMID- 4352816
TI  - [Therapeutic indications in breast cancer].

PMID- 4352817
TI  - [Adrenergic system in the ontogenetic development of experimental animals].

PMID- 4352815
TI  - The actions of penicillin and other antibiotics on bacterial cell wall synthesis.

PMID- 4352818
TI  - [Cyclic nucleotides].

PMID- 4352814
TI  - The activation of coagulation by extracts of mucus: a possible pathway of
      intravascular coagulation accompanying adenocarcinomas.

PMID- 4352819
TI  - [The conformation of natural peptides and their biological activity].

PMID- 4352820
TI  - [Adenyl cyclase and cyclic adenosine-3',5'-monophosphate].

PMID- 4352821
TI  - Lateral inhibition and cognitive masking: a neuropsychological theory of
      attention.

PMID- 4352823
TI  - Arteriographic demonstration of two islet-cell tumors in a patient with Zollinger
      Ellison syndrome.

PMID- 4352822
TI  - [Effect of 25 Mev betatron irradiation on the activity of certain enzymes of the
      liver and corticoadrenal system in rats].

PMID- 4352825
TI  - [Temporal tumor as a diagnostic problem].

PMID- 4352824
TI  - Urinary excretion of cyclic adenosine monophosphate in the detection and
      diagnosis of primary hyperparathyroidism.

PMID- 4352826
TI  - Bilateral carcinoma of the breast.

PMID- 4352827
TI  - [Primary lung adenocarcinoma. Study of a series of 42 cases confirmed by
      autopsy].

PMID- 4352828
TI  - [Giant mixed parotid tumor].

PMID- 4352829
TI  - Genetic regulatory systems in Neurospora.

PMID- 4352830
TI  - The operon revisited.

PMID- 4352831
TI  - The genetics of transmissible plasmids.

PMID- 4352832
TI  - [Changes in various biochemical values in the blood and liver of Xenopus laevis
      females treated with estrogens].

PMID- 4352834
TI  - Confirmation of the 1-20 amino acid sequence of human adrenocorticotrophin.
AB  - The tryptic fragments of natural human adrenocorticotrophin, were separated by
      countercurrent distribution and a correction in positions 25, 26, 27 and 30 was
      made by Riniker et al. (1972) in a study of the fragment containing residues 22
      39. We have purified the remaining tryptic fragments, namely residues 1-8, 9-15,
      16-21 and 17-21, by using ion-exchange chromatography on CM-cellulose and have
      carried out sequence determination by using the subtractive Edman degradation
      procedure and digestion with aminopeptidase M and carboxypeptidase B. These
      results have confirmed the proposed sequence for human adrenocorticotrophin in
      regions 6-7, 10-14 and 17-20, which had previously been arrived at only by
      analogy with the invariant sequence found in the three other mammalian
      adrenocorticotrophin species that had been investigated.

PMID- 4352833
TI  - The effects of glucagon and insulin on adenosine 3':5'-cyclic monophosphate
      concentrations in an organ culture of mature rat liver.
AB  - 1. A modified radioimmunoassay for cyclic AMP was developed from the method of
      Steiner et al. (1969). Cyclic [(3)H]AMP was used as the radioactive tracer. Free
      and antibody-bound nucleotides were separated by adsorption of protein to
      Millipore filters. The assay was used to measure amounts of cyclic AMP down to
      0.1pmol in 50mul. 2. The effect of glucagon on cyclic AMP content in pieces of
      mature rat liver maintained for 6 days in organ culture was studied. 3. Cyclic
      AMP content in the tissue reached a maximum in 5-15min and then decreased. This
      may have been partly due to an inhibitor of glucagon action formed in the tissue.
      Small amounts of cyclic AMP were released into the incubation medium. 4. The
      maximal increase in cyclic AMP content produced by glucagon decreased over 6 days
      in culture. However, liver pieces cultured for 2 and 6 days were more sensitive
      to low concentrations of glucagon than were fresh liver pieces. Glucagon
      concentrations for half-maximal effects were approx. 1mum and 0.05mum for fresh
      liver and 2-day cultured liver respectively. 5. Insulin (3.5mum) lowered the
      cyclic AMP content by 30% in the presence of a submaximal glucagon concentration
      in liver cultured for 2 days. No effect of insulin was demonstrated on fresh
      liver pieces. 6. Insulin and glucagon were rapidly destroyed by fresh liver
      pieces.

PMID- 4352835
TI  - D-3-hydroxybutyrate dehydrogenase from Rhodopseudomonas spheroides. Kinetic
      mechanism from steady-state kinetics of the reaction catalysed by the enzyme in
      solution and covalently attached to diethylaminoethylcellulose.
AB  - 1. The reversible NAD(+)-linked oxidation of d-3-hydroxybutyrate to acetoacetate
      in 0.1m-sodium pyrophosphate buffer, pH8.5, at 25.0 degrees C, catalysed by d-3
      hydroxybutyrate dehydrogenase (d-3-hydroxybutyrate-NAD(+) oxidoreductase, EC
      1.1.1.30), was studied by initial-velocity, dead-end inhibition and product
      inhibition analysis. 2. The reactions were carried out on (a) the soluble enzyme
      from Rhodopseudomonas spheroides and (b) an insoluble derivative of this enzyme
      prepared by its covalent attachment to DEAE-cellulose by using 2-amino-4,6
      dichloro-s-triazine as coupling agent. 3. The insolubilized enzyme preparation
      contained 5mg of protein/g wet wt. of total material, and when freshly prepared
      its specific activity was 1.2mumol/min per mg of protein, which is 67% of that of
      the soluble dialysed enzyme. 4. The reactions catalysed by both the enzyme in
      solution and the insolubilized enzyme were shown to follow sequential pathways in
      which the nicotinamide nucleotides bind obligatorily first to the enzyme.
      Evidence is presented for kinetically significant ternary complexes and that the
      rate-limiting step(s) of both catalyses probably involves isomerization of the
      enzyme-nicotinamide nucleotide complexes and/or dissociation of the nicotinamide
      nucleotides from the enzyme. Both catalyses therefore are probably best described
      as ordered Bi Bi mechanisms, possibly with multiple enzyme-nicotinamide
      nucleotide complexes. 5. The kinetic parameters and the calculable rate constants
      for the catalysis by the soluble enzyme are similar to the corresponding
      parameters and rate constants for the catalysis by the insolubilized enzyme.

PMID- 4352836
TI  - D-3-hydroxybutyrate dehydrogenase from Rhodopseudomonas spheroides. Kinetics of
      radioisotope redistribution at chemical equilibrium catalysed by the enzyme in
      solutions.
AB  - 1. The reversible NAD(+)-linked oxidation of d-3-hydroxybutyrate to acetoacetate
      in 0.1m-sodium pyrophosphate buffer, pH8.5, at 25.0 degrees C, catalysed by d-3
      hydroxybutyrate dehydrogenase (d-3-hydroxybutyrate-NAD(+) oxidoreductase, EC
      1.1.1.30), was studied kinetically at chemical equilibrium by monitoring
      radioisotope redistribution with sodium dl-hydroxy[3-(14)C]butyrate and [4
      (3)H]NAD(+)(labelled in the nicotinamide ring). 2. When all substrates are
      maintained at concentrations approaching saturation (approx. 3-50 times the K(m)
      values) the first-order rate constant for the enzyme-catalysed interconversion of
      NAD(+) and NADH is much smaller than that for the enzyme-catalysed
      interconversion of d-3-hydroxybutyrate and acetoacetate. 3. The rate of
      interconversion of NAD(+) and NADH increases initially with increasing
      concentrations of d-3-hydroxybutyrate and acetoacetate (ratio of concentrations
      maintained constant), passes through a maximum and approaches closely to zero at
      saturating concentrations of the latter substrates. 4. The rates of
      interconversion of NAD(+) and NADH and of d-3-hydroxybutyrate and acetoacetate
      increase with increasing concentration of NAD(+) (up to 66 times its K(m) value)
      and NADH (up to 180 times its K(m) value) (ratio of the concentrations of the
      nicotinamide nucleotides maintained constant). 5. These findings support the
      description of this catalysis as an ordered Bi Bi mechanism with no detectable
      alternative pathway, in which the interconversion of the central ternary
      complexes is not rate-limiting, and provide no evidence for the formation of dead
      end complexes. 6. The solubility of 2,4-dinitrophenylhydrazine in HCl exhibits an
      acidity optimum, the maximum solubility at 25.0 degrees C (3.8mg/ml, 19mm)
      occurring at 2.29m-HCl; in solutions of this acidity acetone 2,4
      dinitrophenylhydrazone is relatively insoluble (0.098mg/ml, 0.413mm).

PMID- 4352837
TI  - The effect of modifying lysine-126 on the physical, catalytic and regulatory
      properties of bovine liver glutamate dehydrogenase.
AB  - 1. The reaction of 4-iodoacetamidosalicylate with bovine liver glutamate
      dehydrogenase is dependent on pH. The pH-activity curve is bell-shaped and can be
      described by apparent pK values of 7.8+/-0.2 and 9.1+/-0.2. 2. Enzyme in which
      lysine-126 has been modified by 4-iodoacetamidosalicylate has unaltered
      sedimentation characteristics except when measured in the presence of GTP and
      NADH. 3. GTP binding to the inhibited enzyme is unaltered. However, GTP can no
      longer promote the binding of a second molecule of NADH, since this is already
      bound to the inhibited enzyme without GTP. 4. The equilibrium binding of ADP,
      GTP, NAD-sulphite and NADH (when measured at low concentrations) was largely
      unchanged by modification. 5. The number of binding sites for 2-oxoglutarate to
      the enzyme-NADH complex were decreased by 60% in an enzyme that has been
      inhibited by 70%.

PMID- 4352838
TI  - The reaction of a histidine residue in glutamate dehydrogenase with diethyl
      pyrocarbonate.
AB  - 1. One mol of diethyl pyrocarbonate will react with one mol of glutamate
      dehydrogenase polypeptide chains to form one mol of N(1)-carbethoxyhistidine.
      Reaction is prevented by NADH. 2. The 1:1 complex has an increased specific
      activity (1.4-2.0-fold). 3. The reason for the activation is discussed. The
      results are not consistent with NADH dissociation from the enzyme-glutamate-NADH
      complex being rate-limiting in the steady state measured. 4. The effects of
      modification on the properties of the enzyme were investigated. The effects of
      GTP and NAD(+) on the enzyme activity are unaltered by activation. NADH binding
      is unaltered and there is no apparent change in the molecular weight. However,
      the activated enzyme can still be further activated by ADP. K(s) for ADP is
      decreased fivefold.

PMID- 4352839
TI  - [Use of 4-aminoazobenzene for studying the activity of the acetylating and
      succinylating systems].

PMID- 4352841
TI  - "If a man have a strong faith".

PMID- 4352840
TI  - [Arterio-scinti-electroradiography, a new diagnostic technic].

PMID- 4352842
TI  - Excitation-contraction coupling in heart. IX. Changes in the intracellular stores
      of calcium in failing hearts due to lack of substrate and oxygen.

PMID- 4352844
TI  - Evaluation of a rapid competitive protein binding assay for progesterone in
      pregnancy and some of its complications.

PMID- 4352843
TI  - Effect of cyclic 3',5'-AMP on the (Na+K)-ATPase of myocardial sarcolemma.

PMID- 4352845
TI  - [Radiological aspects of breast cancer (apropos of 234 cases in women)].

PMID- 4352846
TI  - Location of heme a in cytochrome a. I. Combination of alkyl isonitriles with
      cytochrome a.

PMID- 4352847
TI  - Kinetic studies on hydrogenase. Parahydrogen-orthohydrogen conversion and
      hydrogen-deuterium exchange reactions.

PMID- 4352848
TI  - [The clinical picture and surgical treatment of glomus tumors].

PMID- 4352849
TI  - [Cortisone treatment of mediastinal-pulmonary sarcoidosis: necessity of early
      treatment and place of A.C.T.H. therapy (apropos of an evaluation of 75 cases)].

PMID- 4352850
TI  - [Acute gastroenteritis].

PMID- 4352852
TI  - [Histoautoradiography of digestive tumors. I. Study of a gastric leiomyoma with
      35SO4 and 35S-cysteine].

PMID- 4352851
TI  - [Gastritis, intestinal metaplasia and cancer].

PMID- 4352853
TI  - [Pathological IGG and wart-like endocarditis during cancer of the kidney].

PMID- 4352854
TI  - [Clinical characteristics of secondary polycythemia (apropos of 21 cases)].

PMID- 4352855
TI  - L-amino acid oxidase, phosphodiesterase, total protein and other properties of
      juvenile timber rattlesnake (C. H. horridus) venom at different stages of growth.

PMID- 4352856
TI  - Hypersensitivity to different ACTH peptides.

PMID- 4352857
TI  - Suprailiac lymphography.

PMID- 4352858
TI  - Evolution of cytochrome C molecule.

PMID- 4352859
TI  - Actions of transmitter substances on the neuromuscular junctions of vertebrates
      and invertebrates.

PMID- 4352861
TI  - [Comparative effects of isoproterenol, glucagon, angiotensin and amyl nitrite on
      the 1st derivative of the apex cardiogram].

PMID- 4352860
TI  - [242 cases of acute diarrhea in children in Kinshasa].

PMID- 4352862
TI  - [Progressive myoclonic epilepsy. Clinical, polygraphic and histopathological
      aspects of a case].

PMID- 4352863
TI  - [Serological studies in cattle in the Kabete area (Kenya). 1. Occurrence of
      antibodies against para influenza-3-,IBR-,BDD-virus, chlamydia and Coxiella
      burneti].

PMID- 4352864
TI  - Partial reactions of D-glucose 6-phosphate-1L-myoinositiol 1-phosphate cyclase.
AB  - After removal of tightly bound NAD(+) by using charcoal, a preparation of d
      glucose 6-phosphate-1 l-myoinositol 1-phosphate cyclase catalysed the reduction
      of 5-keto-d-glucitol 6-phosphate and 5-keto-d-glucose 6-phosphate by [4-(3)H]NADH
      to give [5-(3)H]-glucitol 6-phosphate and [5-(3)H]glucose 6-phosphate
      respectively. The position of the tritium atom in the latter was shown by
      degradation. Both enzyme-catalysed reductions were strongly inhibited by 2-deoxy
      d-glucose 6-phosphate, a powerful competitive inhibitor of inositol cyclase. The
      charcoal-treated enzyme preparation also converted 5-keto-d-glucose 6-phosphate
      into [(3)H]myoinositol 1-phosphate in the presence of [4-(3)H]NADH, but less
      effectively. These partial reactions of inositol cyclase are interpreted as
      providing strong evidence for the formation of 5-keto-d-glucose 6-phosphate as an
      enzyme-bound intermediate in the conversion of d-glucose 6-phosphate into 1 l
      myoinositol 1-phosphate. The enzyme was partially inactivated by NaBH(4) in the
      presence of NAD(+). Glucose 6-phosphate did not increase the inactivation, and
      there was no inactivation in the absence of NAD(+). There was no evidence for
      Schiff base formation during the cyclization. d-Glucitol 6-phosphate (l-sorbitol
      1-phosphate) was a good inhibitor of the overall reaction. It did not inactivate
      the enzyme. The apparent molecular weight of inositol cyclase as determined by
      Sephadex chromatography was 2.15x10(5).

PMID- 4352865
TI  - Kinetic properties of the partially purified pyruvate dehydrogenase complex of ox
      brain.
AB  - The properties of a purified preparation of the pyruvate dehydrogenase complex
      from ox brain have been compared with those of a similar preparation from ox
      kidney. A broad pH optimum around 7.8, similar dependence on ionic strength, and
      independence of the nature of the buffer anions or cations characterized
      preparations from both tissues. Michaelis constants for the binding of pyruvate,
      thiamin pyrophosphate, NAD(+) and CoA were also similar. Enzyme from both tissues
      was inhibited by NADH, by copper and other heavy metals, by high concentrations
      of tricarboxylic acid-cycle intermediates, and by preincubation with ATP. Acetyl
      CoA itself did not appear to inhibit these preparations, although some commercial
      preparations of acetyl-CoA did contain an inhibitor. Although oxaloacetate and
      alpha-oxobutyrate were weak inhibitors, a number of other alpha-oxo acids
      including phenylpyruvate did not inhibit. The properties of the pyruvate
      dehydrogenase complex from brain and kidney appeared similar.

PMID- 4352866
TI  - The significance of abrupt transitions in Lineweaver-Burk plots with particular
      reference to glutamate dehydrogenase. Negative and positive co-operativity in
      catalytic rate constants.
AB  - 1. Lineweaver-Burk plots for glutamate dehydrogenase, glucose 6-phosphate
      dehydrogenase and several other enzymes show one or more abrupt transitions
      between apparently linear sections. These transitions correspond to abrupt
      increases in the apparent K(m) and V(max.) with increasing concentration of the
      varied substrate. 2. The generalized reciprocal initial-rate equation for a multi
      site enzyme requires several restrictions to be put on it in order to generate
      such plots. These mathematical conditions are explored. 3. It is shown that the
      effective omission of a term in the denominator of the reciprocal initial-rate
      equation represents a minimal requirement for generation of abrupt transitions.
      This corresponds in physical terms to negative co-operativity followed by
      positive co-operativity affecting the catalytic rate constant for the reaction.
      4. Previous models for glutamate dehydrogenase cannot adequately account for the
      results. On the other hand, the model based on both negative and positive co
      operativity gives a good fit to the experimental points. 5. The conclusions are
      discussed in relation to current knowledge of the structure and mechanism of
      glutamate dehydrogenase.

PMID- 4352867
TI  - The release of spasmogenic substances from human chopped lung tissue and its
      inhibition.
AB  - 1. Human lung tissue, passively sensitized with reaginic antibodies, released
      prostaglandins E(1), E(2) and F(2alpha) in addition to histamine and slow
      reacting substance (SRS-A), when exposed to the appropriate antigen. No rabbit
      aorta contracting substance (RCS) was detected.2. Experiments with rats and
      guinea-pigs showed that the release of RCS is not confined to anaphylactic
      reactions mediated by non-reaginic antibodies but may be a feature of anaphylaxis
      in guinea-pigs alone.3. Human lung tissue gently agitated with a blunt nylon rod
      liberated an E-type prostaglandin and RCS in addition to histamine and SRS-A.4.
      Human isolated bronchial muscle was contracted by RCS.5. Disodium cromoglycate
      antagonized the release of prostaglandins during anaphylaxis but not during
      agitation of human lung tissue, whereas indomethacin blocked the release of
      prostaglandins during agitation and anaphylaxis.6. The release of an E-type
      prostaglandin during anaphylaxis in human lung tissue, which inhibits the further
      release of histamine could be another example of the regulatory role of
      prostaglandins in body functions.

PMID- 4352868
TI  - Inhibition of functional vasodilatation and prostaglandin formation in rabbit
      adipose tissue by indomethacin and aspirin.
AB  - 1. The epigastric adipose depot of rabbits has been used to examine the effect of
      indomethacin, aspirin and nicotinic acid on the free fatty acid release and blood
      flow in fat tissue.2. The prostaglandin formation which occurs in adipose tissue
      during lipolysis is prevented by indomethacin and aspirin. The corresponding
      functional vasodilatation which occurs after infusions of lipolytic substances is
      also abolished by these two anti-inflammatory compounds.3. This finding is
      consistent with the theory that prostaglandin E(2) is the mediator of functional
      vasodilatation in adipose tissue.4. Nicotinic acid sometimes inhibits the release
      of free fatty acids from adipose tissue by preventing activation of the tissue
      lipase. In those experiments in which this inhibition occurred, the
      vasodilatation was also prevented.5. This finding is consistent with the view
      that the prostaglandin E(2) which mediates the functional vasodilatation,
      originates in the triglycerides of the fat tissue.

PMID- 4352869
TI  - Effects of angiotensin, catecholamines and cyclic AMP on calcium storage in
      aortic microsomes.
AB  - 1. The binding of calcium observed in microsomal membranes derived from the
      intimal-medial layer of rabbit aorta was specifically increased by the magnesium
      salt of adenosine triphosphate (Mg-ATP). This calcium uptake was inhibited by
      potassium and sodium.2. Angiotensin II, both in the presence and in the absence
      of Mg-ATP, reduced the binding of calcium and increased the release of membrane
      incorporated calcium. These effects were dose-dependent. Analogues of angiotensin
      II devoid of intrinsic activity, failed to alter the release of calcium.3.
      Dibutyryl-cyclic AMP increased the binding of calcium and reduced the rate of its
      release. The maximal effect was observed at the concentration of 10(-5)M.4. (-)
      Noradrenaline reduced the binding of calcium; this effect was inhibited by
      phenoxybenzamine. Conversely, adrenaline like cyclic AMP, increased the calcium
      binding; the effect of adrenaline was suppressed by a beta-adrenoceptor blocking
      agent.5. These observations demonstrate the existence of membranes in rabbit
      aorta capable of storing calcium. Excitatory drugs seem to affect directly and
      specifically the binding and release of calcium in these membranes.

PMID- 4352870
TI  - Action of botulinum toxin on transmission from sympathetic nerves to the vas
      deferens.
AB  - Botulinum toxin (Type A) depressed or abolished transmission from postganglionic
      nerves to smooth muscle of isolated preparations of guinea-pig and mouse vas
      deferens. The time course of blockade was 2 to 6 times slower than that observed
      with the same concentration of the same batch of toxin on the rat diaphragm.
      Spontaneous excitatory junction potentials were still observed after 7 h
      exposure, indicating that the smooth muscle membrane was still able to respond to
      noradrenaline. Depression of transmission is probably due to a presynaptic action
      of unknown nature.

PMID- 4352871
TI  - Indolealkylamine nerve terminals in cerebral ventricles: identification by
      electron microscopy and fluorescence histochemistry.

PMID- 4352872
TI  - Corticosterone binding to hippocampus: nuclear and cytosol binding in vitro.

PMID- 4352873
TI  - Properties of corticosterone-binding macromolecules from rat brain cytosol.

PMID- 4352874
TI  - Inhibition and excitation of units in paraventricular nucleus after stimulation
      of the septum, amygdala and neurohypophysis.

PMID- 4352875
TI  - [Problems of viruses in the etiology of middle ear inflammation in children].

PMID- 4352876
TI  - Post mortem characteristics of the hepatic microsomal drug oxidising enzyme
      system.

PMID- 4352877
TI  - The mechanism of action of aflatoxin B1 on protein synthesis: observations on
      malignant viral transformed and untransformed cells in culture.

PMID- 4352878
TI  - A new synthesis of furanoid fatty acids: isomerisation of hydroxy-cis-enynoic
      acids by alkali, and on argentous silica gel.

PMID- 4352879
TI  - Early reciprocal inhibition in athetosis.

PMID- 4352880
TI  - [Arrhenoblastoma.  Report of 2 cases].

PMID- 4352881
TI  - Metabolism of NAD after whole-body irradiation. IV. Incorporation of nicotinamide
      by isolated perfused liver and by intact rats.

PMID- 4352882
TI  - [Resistance of Dematiceae and their mutants to various types of irradiation].

PMID- 4352883
TI  - [Continuous prevention of rickets].

PMID- 4352884
TI  - [Adrenal cortex function tests in children with rheumatic fever].

PMID- 4352885
TI  - [Intracytoplasmic collagen fibers].

PMID- 4352886
TI  - [Determination of the age of the fetus by the developmental morphology of bones
      of the base of the skull].

PMID- 4352887
TI  - Pituitary peptide.

PMID- 4352888
TI  - Characterization of murine leukaemia virus-specific DNA present in normal mouse
      cells.

PMID- 4352889
TI  - Similar growth of Chinese hamster cells in the presence of phenethyl alcohol or
      dibutyryl cyclic AMP.

PMID- 4352890
TI  - Fucose-containing glycopeptides from the cell surface of Chinese hamster ovary
      cells grown in the presence or absence of cyclic AMP.

PMID- 4352891
TI  - The role of calcium in insulin secretion.

PMID- 4352893
TI  - [Effect of blood loss on the structure of the peripheral nerve].

PMID- 4352894
TI  - [Determination of para-influenza 3 virus antibodies in the serum and nasal
      secretion of calves and cattle with special reference to hemagglutination-
      inhibiting antibodies].

PMID- 4352892
TI  - [Cytochemical studies of peripheral leukocytes in rheumatoid arthritis].

PMID- 4352895
TI  - The gonadotropin receptor of the human corpus luteum.

PMID- 4352896
TI  - Subclinical peripheral nerve involvement in unilateral Bell's palsy.

PMID- 4352897
TI  - Aerobic and anaerobic energy metabolism in compensatory renal hypertrophy.

PMID- 4352898
TI  - Influence of cadmium ions on contractile response of isolated aortas to
      stimulatory agents.

PMID- 4352899
TI  - Coupled sodium-chloride influx across the brush border of rabbit ileum.

PMID- 4352900
TI  - Sodium dependence of base-line and ADH-stimulated short-circuit current in toad
      bladder.

PMID- 4352901
TI  - Carcinoma of the hepatic ducts: review of 11 cases.

PMID- 4352902
TI  - Inherited constriction fragility of chromosome 2.

PMID- 4352903
TI  - The effect of a lipid-rich diet on the properties and composition of lipoprotein
      particles from the Golgi apparatus of guinea-pig liver.
AB  - 1. A cell fraction rich in Golgi apparatus was isolated from the livers of guinea
      pigs fed on a lipid-rich diet (1.6% cholesterol, 15% corn oil). 2. The Golgi
      cisternae and secretory vesicles contained electron-dense particles which were
      tentatively identified as VLD (very-low-density) and LD (low-density)
      lipoproteins. Particles of moderate electron density, 150-500nm in diameter, were
      seen associated with membranous elements of the Golgi-apparatus cell fraction.
      Disruption of this cell fraction permitted the release of these three species of
      particles, which were separated into particulate lipid, and VLD and LD
      lipoproteins. 3. The large particles of moderate electron density, isolated as
      particulate lipid, were distinct from both species of Golgi particles in their
      chemical composition and in possessing an immunochemically unreactive
      apolipoprotein(s). Morphological observations suggest that the particulate lipid
      arose from cytoplasmic lipid droplets which were present as contaminants of the
      Golgi-rich fraction. 4. The chemical and immunochemical results are consistent
      with the suggestion that the Golgi LD particles are precursors of the VLD
      particles, into which they may be transformed by the addition of both
      triglyceride and cholesteryl ester. The present results provide further support
      for the proposal that the Golgi VLD particles are precursors of the serum VLD
      lipoproteins in the guinea pig. 5. Hepatic Golgi VLD particles isolated from
      guinea pigs fed on the lipid-rich diet contained significantly higher molar
      amounts (relative to protein) of both cholesteryl ester and triglyceride than
      similar particles from animals fed on a normal diet. These results suggest that
      the type of Golgi VLD particle produced from the LD particle is a direct
      consequence of the amount and composition of the dietary lipid. 6. Hepatic Golgi
      LD particles isolated from guinea pigs fed on different diets were similar in
      chemical composition and contained approx. 50% by weight of phospholipid. We
      conclude that the Golgi LD particle is normally present in the Golgi-apparatus
      cell fraction from guinea-pig liver, and may represent the end product of
      lipoprotein biosynthesis in the smooth endoplasmic reticulum. 7. The serum LD
      lipoproteins and Golgi LD particles were quite distinct in chemical composition.
      However, these two lipoprotein species were immunochemically identical and
      exhibited a similar range of flotation rate. It appears unlikely that the Golgi
      LD particles are secreted as the precursors of the serum LD lipoproteins.

PMID- 4352904
TI  - Milk xanthine oxidase type D (dehydrogenase) and type O (oxidase). Purification,
      interconversion and some properties.
AB  - 1. The xanthine oxidase of cow's milk, crude or purified, appears as an oxidase
      (type O), and can be converted almost completely into a NAD(+)-dependent
      dehydrogenase (type D) by treatment with dithioerythritol or dihydrolipoic acid,
      but only to a small extent by other thiols. 2. The D form of the enzyme is
      inhibited by NADH, which competes with NAD(+). 3. The kinetic constants of the
      two forms of the enzyme are similar to those of the corresponding forms of rat
      liver xanthine oxidase. 4. Milk xanthine oxidase is converted into an
      irreversible O form by pretreatment with chymotrypsin, papain or subtilisin, but
      only partially with trypsin. 5. The enzyme as purified shows a major faster band
      and a minor slower band on gel electrophoresis. The slower band is greatly
      reinforced after xanthine oxidase is converted into the irreversible O form by
      chymotrypsin.

PMID- 4352905
TI  - The amino acid sequence of cytochrome c from Allium porrum L. (leek).
AB  - The amino acid sequence of leek cytochrome c was determined with 0.4mumol of
      protein. The sequence was deduced solely from a chymotryptic digest. The
      cytochrome was homologous with other plant cytochromes c of mitochondrial origin.
      Leek cytochrome c has an N-acetylated ;tail' as compared with mammalian
      cytochrome c, and two residues of epsilon-N-trimethyl-lysine. Unlike other plant
      cytochromes c, leek cytochrome c has glutamic acid or glutamine in position 11,
      leucine in position 20 and alanine in position 51. 4-Hydroxyproline partially
      substitutes for proline in position 79. Experimental details are given in a
      supplementary paper that has been deposited as Supplementary Publication SUP
      50012, at the National Lending Library for Science and Technology, Boston Spa,
      Yorks. LS23 7BQ, U.K., from whom copies can be obtained on the terms indicated in
      Biochem. J. (1973) 131, 5.

PMID- 4352906
TI  - The amino acid sequence of cytochrome c from Spinacea oleracea L. (spinach).
AB  - The amino acid sequence of spinach (Spinacea oleracea L., var. Monster Viroflay)
      cytochrome c was determined on 1mumol of protein. The molecule consists of 111
      residues and is homologous with other mitochondrial cytochromes c. Experimental
      details are given in a supplementary paper that has been deposited as
      Supplementary Publication SUP 50013, at the National Lending Library for Science
      and Technology, Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies can be
      obtained on the terms indicated in Biochem. J. (1973), 131, 5.

PMID- 4352907
TI  - The preparation and analysis of a new trinucleotide from yeast ribonucleic acid,
      containing two adjacent 2'-O-methylpentose residues.
AB  - Quantities of the order of 10mg of three alkali-stable trinucleotides were
      prepared from yeast ribonucleic acid. Analyses showed that they were of the type
      N1m-N2m-N3p, where m signifies 2'-O-methylation of the pentose residue. One, Am
      Um-Gp, is newly described.

PMID- 4352908
TI  - A study of the kinetics and mechanism of yeast alcohol dehydrogenase with a
      variety of substrates.
AB  - 1. The kinetics of oxidation of ethanol, propan-1-ol, butan-1-ol and propan-2-ol
      by NAD(+) and of reduction of acetaldehyde and butyraldehyde by NADH catalysed by
      yeast alcohol dehydrogenase were studied. 2. Results for the aldehyde-NADH
      reactions are consistent with a compulsory-order mechanism with the rate-limiting
      step being the dissociation of the product enzyme-NAD(+) complex. In contrast the
      results for the alcohol-NAD(+) reactions indicate that some dissociation of
      coenzyme from the active enzyme-NAD(+)-alcohol ternary complexes must occur and
      that the mechanism is not strictly compulsory-order. The rate-limiting step in
      ethanol oxidation is the dissociation of the product enzyme-NADH complex but with
      the other alcohols it is probably the catalytic interconversion of ternary
      complexes. 3. The rate constants describing the combination of NAD(+) and NADH
      with the enzyme and the dissociations of these coenzymes from binary complexes
      with the enzyme were measured.

PMID- 4352909
TI  - Protein kinase activity in commercially available crystalline yeast alcohol
      dehydrogenase.
AB  - Commercially available crystalline yeast alcohol dehydrogenase contained protein
      kinase activity. Casein and phosvitin were readily phosphorylated, but whole calf
      thymus histone was not. The protein kinase activity was inhibited by KCl, was not
      stimulated by cyclic AMP and could be separated from the alcohol dehydrogenase
      activity by sucrose density centrifugation.

PMID- 4352910
TI  - Interaction between polyuridylic acid and rabbit globin messenger ribonucleic
      acid.
AB  - Poly(U) binds to globin mRNA in 0.1m-NaCl. Studies with ribonuclease digestion of
      this complex suggest that there are polyadenylate-rich sequences in the mRNA
      containing about 30-40 adenylate residues. The sequences appear to be homogenous
      and of approximately the same length for both alpha- and beta-globin mRNA. They
      are most likely located at the 3' terminus of the molecule.

PMID- 4352912
TI  - Equilibrium binding of nicotinamide nucleotides to lactate dehydrogenases.
AB  - 1. No discontinuities were observed during the continuous titration with NADH of
      the lactate dehydrogenases of ox muscle, pig heart, pig muscle, rabbit muscle,
      dogfish muscle or lobster tail muscle. The binding was monitored by either the
      enhanced fluorescence of bound NADH or the quenched fluorescence of the protein.
      A single macroscopic dissociation constant, independent of protein concentration,
      could be used to describe the binding to each enzyme, and there was no need to
      postulate the involvement of molecular relaxation effects. 2. The affinity for
      NADH decreases only threefold between pH6 and 8.5. Above pH9 the affinity
      decreases more rapidly with increasing pH and is consistent with a group of about
      pK9.5 facilitating binding. Muscle enzymes bind NADH more weakly than does the
      pig heart enzyme. 3. Increasing temperature and increasing concentrations of
      ethanol both weaken NADH binding. 4. NADH binding is weakened by increasing ionic
      strength. NaCl is more effective than similar ionic strengths derived from sodium
      phosphate or sodium pyrophosphate. 5. Commercial NAD(+) quenches the protein
      fluorescence of the heart and muscle isoenzymes. Highly purified NAD(+) does not,
      and its binding was monitored by competition for the NADH-binding sites. A single
      macroscopic dissociation constant is sufficient to describe NAD(+) binding at the
      concentrations tested. The dissociation constant is about 0.3mm and is not
      sensitive to changed ionic strength and to changed pH in the range pH6-8.5.

PMID- 4352911
TI  - The inhibition of pig kidney alkaline phosphatase by oxidized or reduced
      nicotinamide-adenine dinucleotide and related compounds.
AB  - 1. The inhibition of alkaline phosphatase by NAD(+), NADH, adenosine and
      nicotinamide was studied. 2. All of these substances except NAD(+) act as
      uncompetitive inhibitors, i.e. double-reciprocal plots are parallel. NAD(+),
      however, is a ;mixed' inhibitor of alkaline phosphatase and is less potent than
      NADH. 3. Inhibition studies with pairs of the inhibitors suggest that, in spite
      of the difference in type of inhibition, NAD(+) and NADH bind to alkaline
      phosphatase at a common site. Adenosine and nicotinamide also seem to bind at the
      NAD site and the binding of adenosine is facilitated by nicotinamide, and vice
      versa. 4. The facilitation may indicate the occurrence of an induced fit for
      NAD(+) and NADH. Attempts to desensitize alkaline phosphatase to NAD(+) and NADH
      inhibition by partial denaturation were unsuccessful. 5. The results are
      discussed in terms of a two-site model in which separate, but interacting,
      regions exist on the enzyme to accommodate the adenosine and nicotinamide
      moieties of NAD, and a single-site model in which the adenosine part of the
      molecule is bound preferentially and this interacts with the nicotinamide
      fraction. 6. The activity of alkaline phosphatase can be changed fourfold by
      alteration of the NAD(+)/NADH ratio. This sensitivity to the redox state of the
      coenzyme could be a means of controlling phosphatase activity.

PMID- 4352913
TI  - Ionic properties of an essential histidine residue in pig heart lactate
      dehydrogenase.
AB  - 1. Pig heart lactate dehydrogenase is inhibited by addition of one equivalent of
      diethyl pyrocarbonate. The inhibition is due to the acylation of a unique
      histidine residue which is 10-fold more reactive than free histidine. No other
      amino acid side chains are modified. 2. The carbethoxyhistidine residue slowly
      decomposes and the enzyme activity reappears. 3. The essential histidine residue
      is only slightly protected by the presence of NADH but is completely protected
      when substrate and substrate analogues bind to the enzyme-NADH complex. The
      protection is interpreted in terms of a model in which substrates can only bind
      to the enzyme in which the histidine residue is protonated and is thus not
      available for reaction with the acylating agent. 4. The apparent pK(a) of the
      histidine residue in the apoenzyme is 6.8+/-0.2. In the enzyme-NADH complex it is
      6.7+/-0.2. 5. Acylated enzyme binds NADH with unchanged affinity. The enzyme is
      inhibited because substrates and substrate analogues cannot bind at the acylated
      histidine residue in the enzyme-NADH complex.

PMID- 4352914
TI  - The use of ternary complexes to study ionizations and isomerizations during
      catalysis by lactate dehydrogenase.
AB  - 1. The binding of oxamate to pig heart and pig muscle isoenzymes of lactate
      dehydrogenase in the presence of NADH was studied by fluorescence titration. The
      dissociation constant of oxamate from the heart enzyme complex is 3mum and from
      the muscle isoenzyme 25mum at pH5. These values quantitatively increase with pH
      as predicted if oxamate can bind only to the enzyme-NADH complex if a group with
      pK6.9 is protonated. There are four non-interacting oxamate-binding sites per
      tetramer. 2. o-Nitrophenylpyruvate is a poor substrate for both isoenzymes but
      has a reasonable affinity to the heart isoenzyme. Initially, it forms an enzyme
      NADH-substrate complex, which can be detected either by protein-fluorescence
      quenching or by NADH-fluorescence quenching. The pH-dependence of the
      dissociation constant of nitrophenylpyruvate also shows that this ternary complex
      can only form if a group with pK6.8 is protonated. Taken with the results of
      chemical-modification experiments, these results allow the pK of 6.8 to be
      assigned to a system probably involving the imidazole side chain of histidine
      195. Formation of a ternary complex from a binary one at pH8 is predicted to
      result in a proton being taken up from solution. 3. Isotope-effect studies with
      NADH and its deuterium analogue show that the rapidly formed ternary complex with
      o-nitrophenylpyruvate slowly isomerizes to give an active ternary complex, which
      then rapidly decomposes to NAD(+). The isomerization is pH-independent, and it is
      suggested that histidine-195 is still protonated in the activated ternary
      complex, which is present before hydride transfer. 4. All four subunits of the
      enzyme are kinetically equivalent with respect to the oxidation of bound NADH by
      o-nitrophenylpyruvate. 5. A partial mechanism for the enzyme is described which
      emphasizes the isomerizations and ionizations involved in forming the reduced
      ternary complex at pH6 and 8.

PMID- 4352915
TI  - A sensitive and accurate gel osmometer.
AB  - 1. A bilayer strip, cut from a thin layer of cross-linked polyacrylamide gel cast
      on to cellulose tissue, forms an open circular loop whose ends are close
      together. Shrinkage of the gel, in response to the osmotic pressure of a non
      penetrating solution, causes a proportional separation of the ends of the loop.
      This is measured with a microscope and micrometer eyepiece. 2. The resulting
      effective sensitivity is about 30 times that of the Sephadex-bead osmometer
      (Ogston & Wells, 1970), i.e. of the order of 5Pa, comparable with that of a
      membrane osmometer. Use of gel up to 70% (w/v) allows the measurement of
      molecular weights, as low as 1500 in favourable cases, with an accuracy of 1-2%.
      The useful range of osmotic pressure is up to 5kPa. A single measurement requires
      0.5ml of solution. Equilibration is completed in 20-30min. 3. The method is
      illustrated by measurements on human serum albumin, ovalbumin, cytochrome c,
      samples of dextrans, polyvinyl alcohol, and polyethylene glycols 6000 and 1000.

PMID- 4352916
TI  - The characterization of a non-histone protein isolated from histone F1
      preparations.
AB  - A non-histone protein was obtained by extraction of nuclei derived from rat liver
      or thymus or ascites-hepatoma cells with 5% (w/v) HClO(4). Separation from
      histone F1 was achieved by chromatography on DEAE-cellulose. The purified
      component P1 was characterized and the formation of complexes with histone F1 and
      polylysine was studied.

PMID- 4352917
TI  - Effect of steady illumination on the binding of carbon monoxide by
      carboxymethylated cytochrome c.
AB  - The quantum yield, [unk], is reported for the photodissociation of CO from
      reduced carboxymethylated cytochrome c. The values of [unk] obtained are low
      relative to that for myoglobin and are pH-independent, being 0.23 at pH6.1 and
      0.27 at pH9.7.

PMID- 4352918
TI  - Relationships between in vivo and in vitro inhibition of acetylcholinesterase
      (AChE) and impairment of neuromuscular transmission in the rat phrenic-nerve
      diaphragm by a tertiary anticholinesterase and its quaternary analogue.

PMID- 4352919
TI  - Glycolytic mechanisms in Ehrlich ascites tumor cells-effects of disulfide
      derivatives of pyridine.

PMID- 4352920
TI  - Phospholipids and phospholipase D in the true slime mold Physarum polycephalum.

PMID- 4352921
TI  - Age differences in the acyl group composition of phosphoglycerides in myelin
      isolated from the brain of the rhesus monkey.

PMID- 4352922
TI  - The retention of arachidonic acid in ethanolamine plasmalogens of rat testes
      during essential fatty acid deficiency.

PMID- 4352923
TI  - Fatty acid amide of glycerylphosphorylethanolamine-a lytic lipid from hog
      stomach.

PMID- 4352924
TI  - Kinetics of lipoprotein lipase activity: effects of the substrate apoprotein on
      reaction velocity.

PMID- 4352925
TI  - Glucose stimulation of fatty acid desaturation in liver of newly-hatched chicks.

PMID- 4352927
TI  - Haemonchus contortus: enzymes. 3. Glutamate dehydrogenase.

PMID- 4352926
TI  - Angiography of the primary retroperitoneal tumors.

PMID- 4352928
TI  - Studies on metabolism of lung fluke genus Paragonimus. VII. Action of bithionol
      on glycolytic and oxidative metabolism of adult worms.

PMID- 4352929
TI  - Reactivity with oxygen of bacterial cytochrome oxidases a1, aa3 and o.

PMID- 4352930
TI  - Effect of luteinizing hormone on 3',5'-cyclic AMP and testosterone production in
      isolated interstitial tissue of rat testis.

PMID- 4352931
TI  - Interaction of transfer RNA with the 30 S subunits of ribosomes in the absence of
      messenger.

PMID- 4352932
TI  - Role of split proteins from 30 S subunits in the ribosome-EF-T GTPase reaction.

PMID- 4352933
TI  - Continuous directional degradation. A novel method for sequence analysis of
      polyribonucleotides.

PMID- 4352935
TI  - Routine isolation of the 70 S RNA of a murine oncornavirus by use of an
      unesterified cellulose column.

PMID- 4352934
TI  - The primary structure of oligonucleotides. Partial apurinization as a method to
      determine the positions of purine and pyrimidine residues.

PMID- 4352936
TI  - Protein phosphokinases of bound and free thyroid polyribosomes.

PMID- 4352937
TI  - Studies on the structure of lipoprotein A of human high density lipoprotein HDL3:
      the spherically averaged electron density distribution.

PMID- 4352938
TI  - The management of bleeding intraductal papilloma of the breast.

PMID- 4352939
TI  - Primary malignant tumors of the liver.

PMID- 4352940
TI  - Corticosteroid release by adrenal tissue from foetal and newborn lambs in
      response to corticotrophin stimulation in a perifusion system in vitro.

PMID- 4352941
TI  - The effect of adrenalectomy on blood corticotrophin in the rat.

PMID- 4352942
TI  - Adrenocortical function in the Australian brush-tailed possum Trichosurus
      vulpecula (Kerr).

PMID- 4352943
TI  - The effect of pyridine nucleotides and cyclic AMP on the synthesis of
      progestational steroids in subcellular fractions of rabbit ovarian interstitial
      tissue.

PMID- 4352944
TI  - The relationship between cortisol and adrenocorticotrophin levels in human
      plasma.

PMID- 4352945
TI  - The effect of intravenous catecholamines on circulating levels of growth hormone,
      corticotrophin and cortisol in man.

PMID- 4352946
TI  - The effect of increased K+ concentration and serotonin on cyclic AMP and
      corticosterone output by dispersed adrenal zona glomerulosa cells.

PMID- 4352947
TI  - Characterization of corticotrophin-like intermediate lobe peptides from rat and
      pig pituitaries, and identification of alpha-melanocyte-stimulating hormone in
      the rat pituitary.

PMID- 4352948
TI  - Studies on proteolytic activity of mycoplasmas: gelatinolytic property.

PMID- 4352949
TI  - Halotolerant collagenolytic activity of Achromobacter iophagus.

PMID- 4352950
TI  - Intersensory interactions in Hermissenda.
AB  - Hair cells of the Hermissenda statocyst respond to photic stimulation. This
      response requires the presence of at least one of the two eyes. Two principal
      hair cell responses to light were observed. The activity of photoreceptors in
      response to a light step is interrupted during firing of contralateral hair
      cells. The intersensory interactions between the statocyst and visual pathway
      underlying these responses were examined with simultaneous intracellular
      recordings. Evidence is presented that the statocyst of Hermissenda is an
      important channel for visual information.

PMID- 4352951
TI  - The quantal nature of synaptic transmission at the neuromuscular junction of a
      spider.
AB  - Spontaneous and evoked release of transmitter at neuromuscular junctions in three
      different leg muscles of a tarantula (Dugesiella hentzi) was investigated. In
      most cases the spontaneous miniature potentials were released independently,
      although bursts from single synaptic junctions occasionally occurred. In contrast
      to recent findings in other arthropod muscles, focal extracellular recording from
      junctional areas revealed that the evoked release of transmitter quanta followed
      Poisson's theorem at low quantal content synaptic junctions in arachnid muscles.

PMID- 4352952
TI  - Evidence for the lack of glycoprotein in the encephalomyocarditis virus particle.

PMID- 4352953
TI  - Ultraviolet irradiation of herpes simplex virus: action spectrum for the survival
      of infectivity in relation to the small-plaque effect.

PMID- 4352954
TI  - The polypeptides of three rhinoviruses.

PMID- 4352955
TI  - The subunits of murine sarcoma-leukaemia virus RNA.

PMID- 4352956
TI  - Interference as a measure of cross-relationships in the vesicular stomatitis
      group of rhabdo viruses.

PMID- 4352957
TI  - The infectivity of the nucleic acid of aerosol-inactivated poliovirus.

PMID- 4352958
TI  - Evaluation of a program of aftercare for patients discharged from the hospital.

PMID- 4352959
TI  - Herpesvirus hominis type I encephalitis treated with cytarabine, an unresolved
      problem in encephalitis.

PMID- 4352961
TI  - Radical artery occlusion by a carpal ganglion. Case report.

PMID- 4352960
TI  - [Effect of chemotherapy on cell kinetics. II. Rauscher and Moloney murine
      leukemias].

PMID- 4352962
TI  - Herpes simplex virus as a source of thymidine kinase for thymidine kinase
      deficient mouse cells: suppression and reactivation of the viral enzyme.
AB  - Thymidine kinase (EC 2.7.1.21)-deficient mouse cells were infected with
      inactivated herpes simplex virus, after which "transformed" cells that produce
      viral thymidine kinase were isolated. Shortly after transformation, the
      expression of the viral enzyme could be suppressed and reactivated with high
      efficiency. On continued multiplication in nonselective medium, the proportion of
      cells producing the viral enzyme decayed exponentially. This decay seemed to
      represent a change in the expression of the viral gene for thymidine kinase
      rather than the loss of the gene from the cells, since the viral enzyme could be
      apparently reactivated in every cell, albeit at a very low frequency.

PMID- 4352963
TI  - Relationship of replication and transcription of Simian Virus 40 DNA.
AB  - RNA produced by the Simian Virus 40 (SV40) mutant tsA30 during lytic infection of
      kidney cells of African green monkeys was examined by RNA-DNA competition
      hybridization. This mutant is temperature-sensitive in a function (gene A) that
      regulates synthesis of viral DNA. No detectable difference between mutant RNA
      synthesized at the permissive temperature (33 degrees ) and wild-type viral RNA
      was found. During continuous infection with the mutant at the restrictive
      temperature (41 degrees ) only early viral RNA was produced. When mutant DNA and
      late RNA synthesis were initiated at the permissive temperature, a shift to the
      restrictive temperature rapidly terminated synthesis of viral DNA but not that of
      late viral RNA. The data indicate that the function of gene A is required before
      synthesis of late viral RNA and that after initiation, the production of late RNA
      continues without further expression of gene A or concomittant viral DNA
      synthesis.

PMID- 4352965
TI  - Interferon: evidence for its glycoprotein nature.
AB  - In an attempt to understand the structure of rabbit interferon, the possibility
      of carbohydrate being part of the molecule was tested. Interferon incubated with
      neuraminidase from Vibrio cholera is homogeneous in charge as revealed by
      isoelectric focusing. Treatment of "asialointerferon" with galactose oxidase (EC
      1.1.3.9) from Dactylium dendroides and subsequent reduction with tritiated sodium
      borohydride yields labeled material with unimpaired antiviral activity. Enzymic
      incorporation of N-[(14)C]acetylneuraminic acid into tritiated asialointerferon
      restores the original charge heterogeneity. The newly generated sialointerferon
      contains both (3)H and (14)C activity. Asialointerferon is retained by an
      affinity column containing phytohemagglutinin from Phaseolus vulgaris and can be
      displaced from the adsorbent by a glycoprotein of known structure. It is
      concluded that rabbit interferon is a glycoprotein containing the terminal
      oligosaccharide sequence sialic acid --> galactose.

PMID- 4352964
TI  - Collagen and procollagen production by a clonal line of Schwann cells.
AB  - A well-characterized line of rat Schwann cells has been examined for its ability
      to produce collagen. About 14% of the [(3)H]proline in the proteins that were
      secreted into the culture medium by the cells was hydroxylated, while only 1% of
      the labeled proteins in the cell layer contained [(3)H]hydroxyproline. Three
      sizes of procollagen polypeptides, of molecular weights about 105,000, 120,000,
      and 155,000, were present in the medium, as well as tropocollagen molecules that
      contained the usual alpha1 and alpha2 chains. Subsequently, the Schwann cells
      ceased producing the smaller collagenous polypeptides, although the total
      [(3)H]hydroxyproline content of the medium was unchanged. The
      [(3)H]hydroxyproline was almost entirely accounted for by the polypeptide of
      155,000 daltons; this peptide was rapidly digested by collagenase or pepsin or
      chymotrypsin. The destruction by pepsin and chymotrypsin indicates that the large
      polypeptide, in contrast to procollagen and tropocollagen, is not in the
      collagenous (helical) conformation. Possibly, this substance is a very early form
      of procollagen that does not fold into the collagen conformation. The data show
      that cells of neuroectodermal origin can synthesize collagen, and also suggest
      that Schwann cells may be responsible for a large proportion of the collagen seen
      in peripheral neurinomas in vivo.

PMID- 4352966
TI  - Primary dysbetalipoproteinemia: predominance of a specific apoprotein species in
      triglyceride-rich lipoproteins.
AB  - Lipoproteins of very low density that are unusually rich in cholesteryl esters
      accumulate in blood plasma in a characteristic primary form of human
      hyperlipoproteinemia. These lipoproteins, which are thought to be products of the
      initial catabolic step in the metabolism of normal triglyceride-rich
      lipoproteins, have beta rather than pre-beta mobility on electrophoresis,
      presumably because they have lost certain protein components from their surface.
      In this study, we have used polyacrylamide gel electrophoresis of apoprotein
      components that are soluble in tetramethylurea to show that the very low-density
      lipoprotein fraction of blood serum from seven patients with hyperlipoproteinemia
      contains unusually large amounts of an arginine-rich protein. Pre-beta migrating,
      very low-density lipoproteins separated from serum of post-absorptive patients
      and chylomicrons obtained after a fat-rich meal contain normal amounts of this
      arginine-rich protein, but beta-migrating, very low-density lipoproteins and
      chylomicron-like particles separated from serum of post-absorptive patients
      contain more than twice as much. These apparently partially degraded lipoproteins
      also contain more tetramethylurea-insoluble protein and smaller amounts of the
      other soluble protein components than their normal counterparts.

PMID- 4352967
TI  - A tumor-associated antigen in human nephroblastomas.
AB  - Antisera prepared against extracts of human nephroblastomas (Wilms' tumors)
      allowed the characterization in these extracts, and in a few extracts of tumors
      of other organs, of a tumor-associated antigen. This antigen is different from
      all previously described antigens, and was named W antigen (W for Wilms). It does
      not seem to be a carcinoembryonic antigen, and hence it could be of viral origin.

PMID- 4352968
TI  - Independent segregation of loci for activation of biologically distinguishable
      RNA C-type viruses in mouse cells.
AB  - Two genetic loci for induction of RNA C-type virus in BALB/c mouse embryo cells
      segregate independently in backcross embryo cell lines. The viruses at these loci
      are shown to be biologically distinguishable. The first, described previously,
      codes for activation of a virus that grows preferentially in NIH Swiss embryo
      cells. The newly detected locus codes for activation of a virus that grows
      poorly, if at all, in NIH Swiss or BALB/c cells, but replicates well in a rat
      cell line. Its serologic properties are different from those of viruses of the
      two major serologic subgroups of murine leukemia virus. The present findings
      provide support for the hypothesis that the loci for virus induction in BALB/c
      cells represent genetic information for C-type viruses and that the endogenous
      viruses are subject to different cellular genetic controls.

PMID- 4352969
TI  - Virus-specific messenger RNA and nascent polypeptides in polyribosomes of cells
      replicating murine sarcoma-leukemia viruses.
AB  - We present evidence that virus-specific RNA is present in polyribosomes of
      transformed cells replicating the murine sarcoma-leukemia virus complex and that
      it serves as messenger RNA for the synthesis of viral-coded proteins. Both virus
      specific RNA (detected by hybridization with the [(3)H]DNA product of the viral
      RNA-directed DNA polymerase) and nascent viral polypeptides (measured by
      precipitation with antiserum to purified virus) were found in membrane-bound and
      free polyribosomes. Membrane-bound polyribosomes contained a higher content of
      both virus-specific RNA and nascent viral polypeptides. From 60 to 70% of viral
      RNA sequences were released from polyribosomes with EDTA, consistent with a
      function as messenger RNA. Maximum amounts of both virus-specific RNA and nascent
      viral polypeptides were found in the polyribosome region sedimenting at about 350
      S.

PMID- 4352970
TI  - Activation of a covalent enzyme-substrate bond by noncovalent interaction with an
      effector.
AB  - The absorption spectrum of an activesite specific chromophoric acyl enzyme,
      sturgeon beta-(2-furyl)-acryloyl-glyceraldehyde-3-phosphate dehydrogenase, is
      reported. This acyl enzyme undergoes all of the catalyzed reactions
      characteristic of the intermediate of the physiological acyl enzyme, 3-phospho-D
      glyceroyl-glyceraldehyde-3-phosphate dehydrogenease. The rates of reactions of
      both these acyl enzymes depend strongly on the extent of interaction of the acyl
      enzyme with the oxidized coenzyme, NAD(+), even where the "redox" properties of
      the coenzyme are not required. Likewise, the spectral properties of chromophoric
      acyl enzyme are affected by the extent of bound NAD. Under the
      pseudophysiological conditions reported herein, there is a stoichiometric
      limitation of two furylacryloyl-acyl groups per enzyme molecule containing four
      covalently-equivalent subunits. The binding of NAD both to the apoenzyme and to
      the diacyl enzyme is heterogeneous: at low extents of NAD occupancy, NAD binding
      is stronger. The binding to acyl enzyme can be quantitatively described by an
      enzyme model involving a tetramer with 2-fold symmetry, and consequently
      containing equal numbers of two classes of sites. NAD binding to difurylacryloyl
      enzyme occurs virtually discretely, first to the two unmodified (tight-binding)
      sites, followed by looser binding to the two acyl-sites. NAD occupancy at these
      latter sites transforms the chromophoric acyl spectrum from that characteristic
      of a model furylacryloyl-thiol ester in H(2)O to a highly perturbed furylacryloyl
      spectrum characteristic of monomeric native "active-thiol" furylacryloyl-enzymes.
      Likewise the acyl reactivity towards arsenolysis depends on the extent of NAD
      bound to the loose sites. Elimination of the tight binding of NAD to the
      difurylacryloyl enzyme tetramer by alkylation of the remaining two free SH groups
      with iodoacetate has no apparent influence on the NAD-dependent furylacryloyl
      spectral perturbation at the "two equivalent acyl sites," even though it
      eliminates the apparent "negative cooperativity" in NAD binding.

PMID- 4352971
TI  - Relationship between post-transcriptional adenylation of herpes virus RNA and
      messenger RNA abundance.
AB  - Analysis of the hybridization kinetics of labeled DNA of herpes simplex virus
      with unlabeled excess RNA from infected cells showed that viral RNA sequences
      form two classes differing in molar concentration. The abundant class constituted
      93.5-99.3% of total virus-specific RNA and was complementary to 14-16% of the
      early DNA (2 hr after infection) and to 19-22% of the late DNA (8 hr after
      infection) in the reproductive cycle of the virus. The early RNA sequences were
      found to be a subset of the late sequences. The scarce sequences constituted 0.7
      6.5% of total virus-specific RNA and were complementary to 28-30% of DNA both
      early and late in the reproductive cycle. In this study, abundant and scarce
      sequences were quantitatively separated on the basis of the finding that abundant
      species are adenylated, i.e., contain post-transcriptionally added poly(A),
      whereas the scarce RNA is not. Thus, nuclear and polyribosomal adenylated RNA
      were complementary to 24 and 22%, respectively, of viral DNA and, in abundance
      competition tests, were found to compete with each other and with abundant RNA
      from infected cells after 8 hr. The nonadenylated polyribosomal RNA was
      complementary to 27% of total viral DNA of which 6% was also complementary to
      adenylated polyribosomal RNA. Hybridization kinetics indicated that each of the
      fractionated adenylated RNA formed two classes complementary to 6 and 21% of
      viral DNA.

PMID- 4352972
TI  - Prophylaxis and immunization in mice by use of virus-free defective T particles
      to protect against intracerebral infection by vesicular stomatitis virus.
AB  - Defective interfering T particles of vesicular stomatitis virus provide
      remarkable protection against viral disease and death when introduced
      intracerebrally in large numbers along with an otherwise rapidly fatal low dose
      of standard infectious virus. This profound prophylactic effect of defective T
      particles is due to homologous autointerference since it is serotype-specific and
      interferon is not induced. This protective effect can be demonstrated only with
      preparations of T particles that have been purified completely free of infectious
      virions. When pure T particles are injected intracerebrally along with large
      doses of infectious virus, they convert an otherwise rapidly fatal disease
      process to a slowly progressing virus infection that generally terminates in
      death after many days of wasting disease and paralysis. Intracerebral injection
      of virus-free T particles alone is apparently innocuous to mice and stimulates
      immunity to massive doses of homologous infectious virus. In vitro, virus-free T
      particles at extremely high multiplicities depress cellular RNA and protein
      synthesis and kill BHK21 cells in culture, but do not exhibit such effects at
      moderately high multiplicities.

PMID- 4352973
TI  - Chemical synthesis and biochemical properties of peptide fragments of
      apolipoprotein-alanine.
AB  - Apolipoprotein-alanine is an apolipoprotein isolated from very-low-density
      lipoproteins of human plasma. This protein contains 79 amino acids and binds
      phosphatidyl choline. Four fragments of this molecule corresponding to sequence
      positions 41-79 (I), 48-79 (II), 55-79 (III), and 61-79 (IV) have been
      synthesized by standard solid-phase methods. The resulting peptides were cleaved
      from the resin and deblocked with liquid HF, then purified by chromatography on
      Sephadex G-50 and DEAE-cellulose. Each purified peptide eluted as a single,
      symmetrical peak, exhibited a single band on polyacrylamide gel electrophoresis,
      and gave an amino-acid analysis in good agreement with the theoretical value.
      Circular dichroism studies indicated that only fragments I and II became more
      helical in the presence of phosphatidyl choline and significantly inhibited the
      reactivation of delipidated beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30), an
      enzyme that requires phosphatidyl choline for activity. When subjected to
      ultracentrifugation at density 1.064 g/ml in the presence of phosphatidyl
      choline, fragments I, II, III, and IV floated to the top of the tube to the
      extent of 85, 50, 13, and 9%, respectively. These results indicate that residues
      55-79 do not contain the minimum determinants required for the binding of
      phospholipid. However, extension of the peptide's N-terminus by seven residues
      produces a molecule that does bind phosphatidyl choline.

PMID- 4352974
TI  - Discrimination between messenger ribonucleic acids by a mammalian translation
      initiation factor.
AB  - A factor from rabbit-reticulocyte ribosome, which stimulates by 5-fold initiation
      of hemoglobin mRNA translation in Krebs ascites cell extracts, was purified to
      homogeneity. The factor, a protein of about 65,000 molecular weight in sodium
      dodecyl sulfate, discriminates between various mRNAs: it stimulates translation
      of alpha globin mRNA and of tobacco mosaic virus RNA, but has only a small effect
      on beta globin mRNA and no effect at all on Mengo virus RNA translation.

PMID- 4352975
TI  - Measurements of rates of adenosine 3':5'-cyclic monophosphate synthesis in intact
      Escherichia coli B.
AB  - A method for labeling adenosine 3':5'-cyclic monophosphate in vivo from precursor
      adenosine followed by quantitative analysis of the labeled nucleotide is
      described. When the labeling period is short and the specific activity of the ATP
      pool is determined, the rate of incorporation of radioactivity corresponds to a
      determination of adenylate cyclase activity in vivo. In E. coli B the specific
      activity of adenylate cyclase in vivo varies under different growth conditions.
      Under all conditions tested, the adenylate cyclase activity in vivo is great
      enough to account for the pattern of accumulation of cyclic AMP. This is in
      contrast to previous adenylate cyclase assays in vitro, where the measured enzyme
      activities were insufficient to account for the amounts of cyclic AMP
      accumulated.

PMID- 4352976
TI  - Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human
      fibroblasts by lipoproteins.
AB  - The activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase (EC 1.1.1.34),
      the rate-limiting enzyme of hepatic cholesterol biosynthesis, is suppressed in
      human fibroblasts cultured in the presence of serum. This enzyme activity
      increases by more than 10-fold after the removal of serum from the medium. The
      rise in enzyme activity requires de novo protein synthesis and is not accompanied
      by changes in the activities of several other cellular enzymes. The factor
      responsible for the suppression of 3-hydroxy-3-methylglutaryl coenzyme A
      reductase activity in cultured fibroblasts is present in the sera of at least
      four mammalian species, and in human serum it is found in the low-density
      lipoproteins. Human high-density lipoproteins, very low-density lipoproteins from
      chicken egg yolk, and the fraction of human serum containing no lipoproteins do
      not suppress the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase.

PMID- 4352978
TI  - ESR and INDO-MO studies of radicals and radical reactions in irradiated single
      crystals of 5-nitro-6-methyluracil.

PMID- 4352979
TI  - Electron spin resonance studies of electron irradiated peptides. A single crystal
      of N-acetylglycine at 77 K.

PMID- 4352977
TI  - Variation of type-B DNA x-ray fiber diagrams with base composition.
AB  - Eight natural DNAs of widely differing base composition have been studied by x
      ray diffraction in fibers at high relative humidity. The resulting type B
      diffraction diagrams showed that all of the DNAs had a 34-A pitch and 3.4-A
      interbase pair separation. However, the intensity distribution on the inner three
      layer lines was a strong function of the base content. In diffraction diagrams of
      very AT-rich DNA, the intensity of the first and third layer line was 2- or 3
      times stronger than in the patterns of GC-rich DNA. These high humidity
      diffraction patterns agree with x-ray scattering from solutions of DNA. The
      results are interpreted to imply that each AT base pair may have a different
      cross section than a GC pair. If this is so, it would appreciably alter the
      currently held ideas concerning DNA recognition.

PMID- 4352980
TI  - [Experimental cerebral tumors of viral etiology in dogs. Their histological
      similarity to human tumors demonstrated by an ultrastructural study of 44
      meningiomas, 19 spongioblastomas and 1 ependymoma].

PMID- 4352981
TI  - [Zieve's syndrome (apropos of 2 cases)].

PMID- 4352982
TI  - [Serum cholinesterase, test of liver cell failure].

PMID- 4352983
TI  - [Emergency laparoscopy (study of 1265 cases)].

PMID- 4352984
TI  - [Nephrotic syndrome due to gold salts (apropos of 4 cases)].

PMID- 4352985
TI  - Dreams and the social environment.

PMID- 4352987
TI  - Lipid metabolism in uremia and the effects of dialysate glucose and oral androgen
      therapy.

PMID- 4352986
TI  - Microlymphangiography of human gastric musosa for the interpretation of early
      spread of gastric cancer.

PMID- 4352989
TI  - Considerations of the middle molecular hypothesis. II. Neuropathy in
      nehprectomized patients.

PMID- 4352988
TI  - An approach to "middle molecules" identification in artificial kidney dialysate,
      with reference to neuropathy prevention.

PMID- 4352990
TI  - Nerve excitability in chronic renal disease.

PMID- 4352991
TI  - Role of pyrophosphate in renal osteodystrophy.

PMID- 4352992
TI  - Viraemia and antibody development in chicks following the administration of
      turkey herpesvirus.

PMID- 4352993
TI  - [State of the childbearing function following chemotherapy for trophoblastic
      disease].

PMID- 4352994
TI  - [Functional state of the adrenal cortex in malignant tumors of the ovaries during
      thio-TEPA treatment].

PMID- 4352996
TI  - Development of a pharmacy care plan.

PMID- 4352995
TI  - [Characteristics of the carcinogenic action of dibutylnitrosamine].

PMID- 4352997
TI  - Adenovirus in the sinuses of an asthmatic patient with apparent selective
      antibody deficiencies.

PMID- 4352998
TI  - Acute ulcerative colitis associated with cytomegalic inclusion virus.

PMID- 4352999
TI  - Bone collagen metabolism in vitamin D deficiency.
AB  - Radioisotope studies have shown that collagen synthesized in the shafts of bones
      from rachitic rats and chicks is similar in chain composition to that normally
      synthesized. However, the extent of lysine hydroxylation in both alpha1- and
      alpha2-chains is increased, by approx. 15-30% in the rat and by 50% in the chick.

PMID- 4353001
TI  - The effect of glucose, insulin and noradrenaline on lipolysis, and on the
      concentrations of adenosine 3':5'-cyclic monophosphate and adenosine 5'
      triphosphate in adipose tissue.
AB  - Glycerol release and tissue concentrations of ATP and cyclic AMP were followed
      during the incubation of adipose tissue with or without glucose, insulin and
      noradrenaline. Glucose plus insulin or, to a lesser extent, glucose alone
      increased the accumulation of glycerol during incubations both with and without
      noradrenaline by slowing the decline in the rate of glycerol release with time.
      Insulin alone decreased the accumulation by accelerating the fall in glycerol
      release. In the absence of noradrenaline, ATP and cyclic AMP concentrations were
      not significantly affected by insulin or glucose. With noradrenaline or
      noradrenaline plus insulin the ATP concentration gradually fell. With
      noradrenaline plus glucose the ATP concentration fell rapidly and then
      stabilized, or, if insulin was also present, returned to the control value. In
      the presence of noradrenaline, the concentration of cyclic AMP rose during the
      first 20min and then fell. Insulin lowered the peak concentration of cyclic AMP,
      but glucose had no effect either on the peak value or the fall in the
      concentration of the nucleotide. The increase and fall in the concentration of
      cyclic AMP with noradrenaline or noradrenaline plus insulin bore similarities to
      the increase and decline in the lipolytic rate in incubations without glucose. It
      is proposed that glucose stimulates ATP production by furnishing glycerol 1
      phosphate and thus removing free fatty acids, but that it can influence lipolysis
      by a mechanism which is distinct from any which is mediated by free fatty acids,
      possibly by inhibiting the inactivation of the lipase.

PMID- 4353000
TI  - Hepatic redox state and gluconeogenesis from lactate in vivo in the rat.
AB  - 1. To examine the role of the hepatic redox state on the rate of gluconeogenesis
      the effects of sodium crotonate injection (6mmol/kg body wt.) on rat liver
      metabolite concentrations and gluconeogenesis from lactate were studied in vivo.
      2. Crotonate caused a marked oxidation of cytoplasmic and mitochondrial redox
      couples; decreases were observed in the ratios of [lactate]/[pyruvate], [glycerol
      3-phosphate]/[dihydroxyacetone phosphate], [hydroxybutyrate]/[acetoacetate] and
      measured [NAD(+)]/[NADH]. 3. Increases occurred in the liver concentrations of
      all gluconeogenic intermediates from pyruvate through to glucose 6-phosphate, but
      there was no change in lactate concentration. 4. To determine whether
      gluconeogenesis from lactate was altered by the more-oxidized hepatic redox state
      l-[2-(14)C]lactic acid was infused into the inferior vena cava (50mumol/min per
      kg body wt.) and the incorporation of radioactivity into blood glucose was
      measured. 5. Administration of crotonate transiently decreased the rate of
      lactate incorporation into glucose but within a few minutes the rate of
      incorporation returned to that of the controls. 6. The results indicate that in
      these experiments alteration of the NAD(+)-NADH systems of cytoplasm and
      mitochondria to a more-oxidized state did not change the rate of gluconeogenesis.

PMID- 4353003
TI  - The analysis of polydeoxyribonucleotides by digestion with phosphatase and
      phosphodiesterases.

PMID- 4353002
TI  - The absence of an integrated copy of mitochondrial DNA in the nuclear genome of
      Tetrahymena pyriformis.

PMID- 4353005
TI  - [Intrarenal localization of tritiated angiotensin in the mesangial cells, using
      radioautography].

PMID- 4353004
TI  - Ribosomal RNA cistron topography in Escherichia coli.

PMID- 4353006
TI  - [Possibilities offered by new indomonocarbocyanines for functional exploration of
      the liver].

PMID- 4353007
TI  - [Presence of cellular antigens in the serum of hamsters with tumors caused by the
      subcutaneous injection of hamster fibroblasts transformed by the SV40 virus].

PMID- 4353008
TI  - [Action of noradrenaline, isoprenaline, angiotensin and various adrenergic
      inhibitors on rat cardiac output measured by the dilution method].

PMID- 4353009
TI  - [Effect of an early ACTH injection on mammary and adrenal gland development in
      the mouse fetus in utero].

PMID- 4353010
TI  - [Cells of the reticuloendothelial system of the splenic pulp revealed by
      histoenzymatic methods in various rodents].

PMID- 4353011
TI  - [Adenosine triphosphate (ATP), cyclic adenosine 3'5' monophosphate (cycl 3'5'
      AMP) and insulin secretion].

PMID- 4353013
TI  - Radiologic evaluation of soft tissue tumors. A retrospective study.

PMID- 4353012
TI  - A clinicopathologic analysis of adriamycin cardiotoxicity.

PMID- 4353014
TI  - Perineural invasion and anaplastic transformation of verrucous carcinoma.

PMID- 4353016
TI  - Cirrhosis and hepatoma occurring at Boston City Hospital (1917-1968).

PMID- 4353015
TI  - Sinus histiocytosis with massive lymphadenopathy. Report of a case associated
      with elevated EBV antibody titers.

PMID- 4353017
TI  - Benign liver cell tumors. Classification and ultrastructural pathology.

PMID- 4353018
TI  - Malignant mixed tumor of the gallbladder.

PMID- 4353019
TI  - Pituitary insufficiency, inappropriate antidiuretic hormone (ADH) secretion, and
      carcinoma of the bronchus.

PMID- 4353020
TI  - Benign lipoblastomatosis. An analysis of 35 cases.

PMID- 4353021
TI  - Studies on the relationship between the catecholamine distribution in the atrium
      and the specific granules present in atrial muscle cells. 1. Isolation of a
      purified specific granule subfraction.

PMID- 4353022
TI  - Techniques for studying adrenergic transmitter release in an isolated perfused
      artery.

PMID- 4353023
TI  - New approaches to treatment of osteogenesis imperfecta.

PMID- 4353024
TI  - [Potential generation in bilayer lipid membranes in the system NAD-H-flavin-Q6
      02].

PMID- 4353026
TI  - Synaptic frequency demodulation.

PMID- 4353025
TI  - Thermal activation of the cyclic AMP stimulated sodium transport across isolated
      toad bladder and Na+-K+ ATPase in toad bladder homogenates.

PMID- 4353028
TI  - Sleep in parabiosis.

PMID- 4353027
TI  - Crayfish neuromuscular junction: facilitation with constant nerve terminal
      potential.

PMID- 4353029
TI  - Sleep in the giant South American armadillo Priodontes giganteus (Edentata,
      Mammalia).

PMID- 4353030
TI  - Induction of ingestive responses by cAMP applied into the rat hypothalamus.

PMID- 4353031
TI  - Vesicle hypothesis: effect of nerve stimulation on the synaptic vesicles of motor
      endplates.

PMID- 4353032
TI  - The influence of some biogenic amines and cyclic N-2-O-dibutyryl-adenosine-3',5'
      monophosphate on glycogen content in rat brain slices.

PMID- 4353033
TI  - The influence of propranolol and dibenzyline on glycogenolytic effects of some
      biogenic amines in rat brain slices.

PMID- 4353034
TI  - Milk microsomes, viruses, and the milk fat globule membrane.

PMID- 4353035
TI  - Pea phytohemagglutinin selective agglutination of tumour cells.

PMID- 4353036
TI  - Radioimmunological determination of plasma cortisol.

PMID- 4353037
TI  - Behaviour of a guanidine-dependent strain of poliovirus 1 in sucrose density and
      pH gradients.

PMID- 4353038
TI  - Thiopyrimidines: specific inhibitors of poliovirus induced early cell damages.

PMID- 4353039
TI  - Gas-liquid and thin-layer chromatography of some 3- and 3,x-substituted pyrenes.

PMID- 4353041
TI  - Layer pre-loading in partition thin-layer chromatography of amino acids.

PMID- 4353040
TI  - Circular thin-layer chromatography for diagnosis and follow-up of neural crest
      tumours.

PMID- 4353043
TI  - Acquisition of parainfluenza 3 virus infection by hospitalized children. I.
      Frequencies, rates, and temporal data.

PMID- 4353042
TI  - Generation of ATP during cytochrome-linked anaerobic electron transport in
      propionic acid bacteria.

PMID- 4353044
TI  - Viral interference with exoerythrocytic forms of malaria (Plasmodium gallinaceum)
      in ovo.

PMID- 4353045
TI  - Interference mediated by a variant of Sindbis virus. II. Actinomycin D-sensitive
      interference in the absence of interferon.

PMID- 4353046
TI  - An outbreak of a febrile disease (Izumi fever) associated with high anti-eb virus
      antibody titers.

PMID- 4353048
TI  - Some biochemical studies on the nonspecific acid phosphomonoesterases of
      Dirofilaria immitis.

PMID- 4353047
TI  - The establishment of cultured cell lines from the patients with Izumi fever and
      infectious mononucleosis like diseases.

PMID- 4353049
TI  - Basic mechanisms of aging in the neuromuscular system.

PMID- 4353050
TI  - Alterations in lipoprotein pattern in liver plasma membranes from rats of
      different ages.

PMID- 4353051
TI  - Some properties of seryl-tRNA synthetase from rat liver.

PMID- 4353052
TI  - Biosynthesis of collagen (14C)hydroxyproline and (14C)hydroxylysine during
      maturation of chick embryos.

PMID- 4353053
TI  - Rearing experience, stress and adrenocorticosteroids in the rhesus monkey.

PMID- 4353054
TI  - Influence of environmental temperature on the sleep-wakefulness cycle in the rat.

PMID- 4353056
TI  - [News in virology].

PMID- 4353057
TI  - [Therapeutic results with Iruxol in ulcus cruris, decubitus ulcer and burns].

PMID- 4353055
TI  - [Pulmonary metastases of salivary gland cylindromas (apropos of 3 cases)].

PMID- 4353059
TI  - [Acute disseminated intravascular coagulation in an obstetrical unit. Study of 9
      cases. Diagnostic criteria. Therapeutic management].

PMID- 4353058
TI  - [Clinical and therapeutic study of 14 cases of eclampsia in an intensive care
      unit].

PMID- 4353060
TI  - [Osmotic nephropathy. Specific iatrogenic disease or nonspecific tubular
      reaction?].

PMID- 4353061
TI  - [Amniotic embolism].

PMID- 4353062
TI  - [Myxedema coma. Study of 3 cases].

PMID- 4353063
TI  - [Diagnosis and treatment of pelvic pain of genital origin in women].

PMID- 4353064
TI  - Does the desert black snake venom inhibit release of acetylcholine from motor
      nerve endings?

PMID- 4353065
TI  - [Analysis of the tumorous transformation of tissues. 3. Comparison of the changes
      in creatine kinase activity during embryogenesis and blastomogenesis].

PMID- 4353066
TI  - [Effect of the carcinogens dimethylnitrosamine and 1,2,5,6-dibenzanthracene and
      of the non-carcinogenic substance 1,2,3,4-dibenzanthracene on the enzyme activity
      in a cell culture of primary neonatal rat explants].

PMID- 4353068
TI  - Cytologic diagnosis of salivary gland tumors by aspiration biopsy.

PMID- 4353067
TI  - Cytologic detection of minute ovarian, endometrial and breast carcinomas, with
      emphasis on clinical-pathological approaches.

PMID- 4353069
TI  - The mechanisms of testosterone action of the sebaceous glands of the Syrian
      hamster.

PMID- 4353070
TI  - Three sites for hormonal control of the pigment cell.

PMID- 4353071
TI  - Complications of antimicrobial therapy.

PMID- 4353072
TI  - Microbiologic studies on young infants with lower respiratory tract disease.

PMID- 4353073
TI  - Amebic liver abscess in childhood. A case study of a 21-month-old Thai child and
      a literature review.

PMID- 4353075
TI  - False positive roentgenologic diagnosis of small intracanalicular acoustic
      neurinomas.

PMID- 4353074
TI  - Pneumonia and massive pleural effusion associated with adenovirus type 7.

PMID- 4353076
TI  - Radiation therapy of the glomus jugulare tumor.

PMID- 4353077
TI  - [Case of transitory gynecomasty with hyperestrogenism of non-tumoral testicular
      origin].

PMID- 4353078
TI  - [Radioimmunoassays of aldosterone and plasma renin activity. Application to the
      diagnosis of primary aldosteronism].

PMID- 4353079
TI  - An 18-month longitudinal lymphographic study of filarial diseases in dogs
      infected with Brugia pahangi (Buckley and Edeson, 1956).

PMID- 4353080
TI  - A study of some enzymes of glycerolipid biosynthesis in rat liver after subtotal
      hepatectomy.
AB  - 1. The accumulation of triglyceride in the liver remnant after subtotal
      hepatectomy (removal of 82% of the liver) exceeded that described for partial
      hepatectomy (removal of 70% of the liver). 2. Palmitoyl-CoA synthetase, glycerol
      phosphate acyltransferase and diglyceride acyltransferase activities were
      measured in the microsomal fraction, and phosphatidate phosphohydrolase activity
      was measured in the particle-free supernatant fraction, prepared from the liver
      remnant at various times after subtotal hepatectomy. 3. The only enzyme showing a
      significant change in specific activity was phosphatidate phosphohydrolase. The
      specific activity was approximately fivefold that of the control value at 6h
      after operation and threefold that of the control at 10, 16 and 24h after
      operation. A smaller increase in the specific activity of the enzyme in sham
      operated animals occurred only at 6h after operation. 4. However, at this time
      the total phosphohydrolase activity of the remaining liver in the sham-operated
      rats was approximately threefold that in hepatectomized rats. 5. Injection of
      actinomycin D prevented the increase in activity of phosphatidate
      phosphohydrolase but did not prevent the accumulation of triglyceride.

PMID- 4353081
TI  - The use of deoxyribonucleic acid-cellulose chromatography and isoelectric
      focusing for the characterization and partial purification of steroid-receptor
      complexes.
AB  - 1. Two characteristic properties of the specific high-affinity steroid-binding
      proteins or receptors, their ability to bind to DNA-cellulose and their
      relatively acidic isoelectric point, have been exploited as a means of
      purification. These two fundamental properties distinguish the receptors from the
      steroid-binding proteins in serum and the non-specific low-affinity steroid
      binding proteins in hormone-responsive cells. 2. A significant degree of
      purification of both cytoplasmic and nuclear steroid-receptor complexes can be
      achieved with practical facility by these procedures. The purity of the receptor
      complexes is sufficient to enable studies on their possible control of metabolic
      processes to be investigated in the future. 3. After extensive purification the
      physicochemical properties of the cytoplasmic androgen-receptor complex, such as
      sedimentation coefficient, were unchanged. Further, the purified complex fully
      retained at least one of its fundamental physiological properties, namely the
      ability to transfer 5alpha-dihydrotestosterone (17beta-hydroxy-5alpha-androstan-3
      one) into chromatin in vitro. 4. The methods may also be employed for studying
      the changes in the structure and properties of the receptor complexes that are an
      essential prerequisite for the transfer of cytoplasmic receptor complexes into
      nuclear chromatin. The temperature-dependence of the binding of androgen-receptor
      complexes into chromatin is essentially due to a major change in cytoplasmic
      receptor complex before its attachment to nuclear chromatin. 5. The resolution of
      these analytical procedures was sufficient to enable a critical comparison of the
      receptor proteins from different male accessory glands to be undertaken. From
      these studies, no substantial evidence in support of the tissue specificity of
      androgen receptors could be established; rather the receptors from different
      androgen-dependent glands were remarkably similar in physicochemical properties.
      6. Although the methods were initially developed for the partial purification of
      androgen-receptor complexes, they are equally suitable for the prompt and
      extensive purification of oestrogen-receptor and progesterone-receptor complexes.

PMID- 4353082
TI  - A reappraisal of the effects of adenosine 3':5'-cyclic monophosphate on the
      function and morphology of the rat prostate gland.
AB  - 1. A comparison was made of the binding of 5alpha-dihydrotestosterone (17beta
      hydroxy-5alpha-androstan-3-one) and cyclic AMP in the rat prostate gland.
      Distinct binding mechanisms exist for these compounds, and cyclic AMP cannot
      serve as a competitor for the 5alpha-dihydrotestosterone-binding sites and vice
      versa. In contrast with the results obtained with 5alpha-dihydrotestosterone,
      very small amounts of cyclic AMP are retained in nuclear chromatin and the
      overall binding of this cyclic nucleotide is not markedly affected by castration.
      2. Androgenic stimulation does not lead to major increases in the adenylate
      cyclase activities associated with any subcellular fraction of the prostate
      gland. Accordingly, changes in the concentration of cyclic AMP in the prostate
      gland after hormonal treatment are likely to be small, but these were not
      measured directly. 3. When administered to whole animals in vivo, small amounts
      of non-degraded cyclic AMP are found in the prostate gland but sufficient to
      promote an activation of certain carbohydrate-metabolizing enzymes in the cell
      supernatant fraction. The stimulatory effects of cyclic AMP were not evident with
      cytoplasmic enzymes engaged in polyamine synthesis or nuclear RNA polymerases.
      These latter enzymes were stimulated solely by the administration of
      testosterone. 4. By making use of antiandrogens, a distinction can be drawn
      between the biochemical responses attributable to the binding of 5alpha
      dihydrotestosterone but not of cyclic AMP. Evidence is presented to suggest that
      the stimulation of RNA polymerase, ornithine decarboxylase and S-adenosyl-l
      methionine decarboxylase is a consequence of the selective binding of 5alpha
      dihydrotestosterone. Only the stimulation of glucose 6-phosphate dehydrogenase
      can be attributed to cyclic AMP or other metabolites of testosterone. 5. Overall,
      this study indicates that the formation of cyclic AMP is not a major feature of
      the androgenic response and affects only a restricted number of biochemical
      processes. Certainly, cyclic AMP cannot be considered as interchangeable with
      testosterone and its metabolites in the control of the function of the prostate
      gland. This difference is additionally emphasized by the failure of cyclic AMP to
      restore the morphology of the prostate gland in castrated animals; morphological
      restoration only follows the administration of androgens.

PMID- 4353083
TI  - Induction and suppression of the key enzymes of glycolysis and gluconeogenesis in
      isolated perfused rat liver in response to glucose, fructose and lactate.
AB  - 1. Measurements were made of the activities of the four key enzymes involved in
      gluconeogenesis, pyruvate carboxylase (EC 6.4.1.1), phosphoenolpyruvate
      carboxylase (EC 4.1.1.32), fructose 1,6-diphosphatase (EC 3.1.3.11) and glucose 6
      phosphatase (EC 3.1.3.9), of serine dehydratase (EC 4.2.1.13) and of the four
      enzymes unique to glycolysis, glucokinase (EC 2.7.1.2), hexokinase (EC 2.7.1.1),
      phosphofructokinase (EC 2.7.1.11) and pyruvate kinase (EC 2.7.1.40), in livers
      from starved rats perfused with glucose, fructose or lactate. Changes in
      perfusate concentrations of glucose, fructose, lactate, pyruvate, urea and amino
      acid were monitored for each perfusion. 2. Addition of 15mm-glucose at the start
      of perfusion decreased the activity of pyruvate carboxylase. Constant infusion of
      glucose to maintain the concentration also decreased the activities of
      phosphoenolpyruvate carboxylase, fructose 1,6-diphosphatase and serine
      dehydratase. Addition of 2.2mm-glucose initially to give a perfusate sugar
      concentration similar to the blood sugar concentration of starved animals had no
      effect on the activities of the enzymes compared with zero-time controls. 3.
      Addition of 15mm-fructose initially decreased glucokinase activity. Constant
      infusion of fructose decreased activities of glucokinase, phosphofructokinase,
      pyruvate carboxylase, phosphoenolpyruvate carboxylase, glucose 6-phosphatase and
      serine dehydratase. 4. Addition of 7mm-lactate initially elevated the activity of
      pyruvate carboxylase, as also did constant infusion; maintenance of a perfusate
      lactate concentration of 18mm induced both pyruvate carboxylase and
      phosphoenolpyruvate carboxylase activities. 5. Addition of cycloheximide had no
      effect on the activities of the enzymes after 4h of perfusion at either low or
      high concentrations of glucose or at high lactate concentration. Cycloheximide
      also prevented the loss or induction of pyruvate carboxylase and
      phosphoenolpyruvate carboxylase activities with high substrate concentrations. 6.
      Significant amounts of glycogen were deposited in all perfusions, except for
      those containing cycloheximide at the lowest glucose concentration. Lipid was
      found to increase only in the experiments with high fructose concentrations. 7.
      Perfusion with either fructose or glucose decreased the rates of ureogenesis;
      addition of cycloheximide increased urea efflux from the liver.

PMID- 4353084
TI  - Regulation of renal gluconeogenesis by calcium ions, hormones and adenosine 3':5'
      cyclic monophosphate.
AB  - 1. The effect of Ca(2+), glucagon, adrenaline and adenosine 3':5'-cyclic
      monophosphate on gluconeogenesis by rat kidney-cortex slices was studied. 2.
      Glucose formation from a range of substrates, with the exception of glycerol, was
      increased by an increase in extracellular Ca(2+) concentration. 3. Hormones and
      adenosine 3':5'-cyclic monophosphate, at low Ca(2+) concentrations, stimulated
      glucose production from several substrates, but not from glycerol, fructose,
      malate or fumarate. 4. Hormonal stimulation was not detected in the absence of
      Ca(2+) or at 2.5mm-Ca(2+). 5. Ca(2+), hormones and adenosine 3':5'-cyclic
      monophosphate had no effect on phosphoenolpyruvate carboxylase activity. 6. It is
      proposed that Ca(2+) and adenosine 3':5'-cyclic monophosphate-mediated hormone
      action activate the same rate-limiting step in gluconeogenesis: this step is
      tentatively identified as the rate of transfer of substrates across the
      mitochondrial membrane.

PMID- 4353085
TI  - Adenosine 3':5'-cyclic monophosphate concentrations and phosphodiesterase
      activities during axenic growth and differentiation of cells of the cellular
      slime mould Dictyostelium discoideum.
AB  - During growth of myxamoebae of Dictyostelium discoideum (strain Ax-2) in axenic
      medium, the myxamoebae secrete cyclic AMP. As the cells leave the exponential
      phase of growth and enter the stationary phase, there is an approximate doubling
      of the intracellular cyclic AMP content, but the amount of extracellular cyclic
      AMP remains proportional, at all times, to the number of myxamoebae present.
      During development of axenically grown myxamoebae, there is first a rise in the
      intracellular concentration of cyclic AMP, followed by a rise in the amount of
      extracellular cyclic AMP, which reaches a peak at the time of aggregation and
      then declines. There is a second peak in the amount of extracellular cyclic AMP
      found at the time of fruiting-body formation, but this second peak is not
      associated with a rise in the intracellular cyclic AMP concentration. Controls
      thus exist over the synthesis and secretion of cyclic AMP. Evidence is presented
      for the belief that the activity of the adenylate cyclase enzyme controls the
      amount of cyclic AMP synthesized rather than the activity or amount of cyclic AMP
      phosphodiesterase present. Similar changes occur in extracellular cyclic AMP and
      phosphodiesterase concentrations during incubation of myxamoebae in buffered
      suspensions to those occuring during the first few hours of development of such
      cells on solid media, but the timing of these changes is different.

PMID- 4353086
TI  - The mode of action of adenosine 3':5'-cyclic monophosphate in mammalian islets of
      Langerhans. Effects of insulin secretagogues on islet-cell protein kinase
      activity.
AB  - 1. Protein kinase activity was measured in islets of Langerhans that had been
      incubated in the presence of agents known to affect insulin release. 2. Glucagon,
      theophylline, caffeine and 3-isobutyl-1-methylxanthine, agents that raise cyclic
      AMP concentrations in islet cells and stimulate insulin release, increased
      protein kinase activity. Adrenaline and diazoxide, agents that decrease cyclic
      AMP concentrations and inhibit insulin secretion, decreased the activity. 3. The
      increase in protein kinase activity produced by different concentrations of 3
      isobutyl-1-methylxanthine was apparently related to the increase in intracellular
      concentrations of cyclic AMP. 4. The sulphonylureas, tolbutamide and
      glibenclamide, agents that increase insulin release, also increased the protein
      kinase activity; however, leucine, arginine and xylitol, which also stimulate
      insulin release, were without effect on the kinase activity. 5. Increasing the
      glucose concentration of the incubation medium from 2 to 20mm had no effect on
      protein kinase activity. Further, the ability of 3-isobutyl-1-methylxanthine to
      increase the protein kinase activity was not affected by the glucose
      concentration of the incubation medium. 6. These results suggest that agents
      which affect insulin secretion by altering cyclic AMP concentrations may exert
      their effects on hormone release by altering the activity of a cyclic AMP
      dependent protein kinase in islet cells.

PMID- 4353087
TI  - Comparative studies on the carbohydrate-containing membrane components of normal
      and adenosine 3':5'-cyclic monophosphate-treated Chinese hamster ovary cells.
AB  - 1. We investigated some of the changes in plasma-membrane composition that
      accompany the alteration in cell growth and morphology induced by treating
      Chinese-hamster ovary cells with dibutyryladenosine 3':5'-cyclic monophosphate
      (dibutyryl cyclic AMP). 2. A double-labelling technique was employed in which
      normal cells were given (14)C-labelled precursor, and those treated with
      dibutyryl cyclic AMP were given (3)H label. l-Leucine, d-glucosamine, and l
      fucose were used to label the membranes. 3. After 3 days growth, the two
      populations of cells were harvested by trypsin treatment, the cells were pooled,
      and plasma membranes isolated. Proteins and glycoproteins of the membranes were
      separated by electrophoresis on sodium dodecyl sulphate-polyacrylamide gels, and
      the radioactive profiles for (14)C and (3)H and the staining patterns with Amido
      Black were compared. 4. Although certain components of the membrane from treated
      cells showed marked quantitative changes, there was neither major addition nor
      major deletions of components. 5. Complete proteolysis of the mixed membranes, of
      the material released from the cell surface by trypsin, and of the glycoproteins
      released from the cells into the medium, gave a series of radioactive
      glycopeptides when either fucose or glucosamine was employed as precursor. 6.
      After such glycopeptides were fractionated on columns of Sephadex G-50, marked
      differences in the elution profiles of (3)H and (14)C were noted. Dibutyryl
      cyclic AMP evidently causes alterations in the overall composition of the
      carbohydrate components of the cell surface. It was not possible to decide
      whether this was solely the result of the same glycoproteins being formed but in
      different proportions, or the result of modifications of oligosaccharide side
      chains on some of the glycoproteins. 7. Some of the changes were not unlike the
      reverse of those that accompany the transformation of fibroblasts by oncogenic
      viruses, and our results lend credence to the idea that the lowered amount of
      cyclic AMP noted in transformed cells is responsible for their altered surface
      properties.

PMID- 4353088
TI  - A comparison of D-inositol 1:2-cyclic phosphate 2-phosphohydrolase with other
      phosphodiesterases of kidney.
AB  - 1. The ability to hydrolyse various phosphodiesterase substrates was examined in
      subcellular fractions of rat kidney and in serial slices of the kidneys of mouse,
      rat, guinea pig and ox cut from the cortex perimeter inwards. 2. d-Inositol 1:2
      cyclic phosphate 2-phosphohydrolase could be clearly distinguished from
      phosphodiesterases which hydrolyse 2':3'- and 3':5'-cyclic AMP and p-nitrophenyl
      thymidine 5'-phosphate (phosphodiesterase I). The hydrolysis of sn-glycero-3
      phosphorylcholine showed a distribution identical with that of particle-bound d
      inositol 1:2-cyclic phosphate 2-phosphodiesterase, but there was a 30-fold
      difference in the ratio of enzyme activities between the rat and guinea pig. 3.
      In rat and mouse kidney, d-inositol 1:2-cyclic phosphate 2-phosphohydrolase is
      virtually all membrane bound and in the outer cortex, whereas in guinea-pig
      kidney the enzyme is almost entirely soluble and located throughout the kidney
      tissue. Some properties of the soluble enzyme are described. 4. Distribution and
      histochemical studies indicated that in the rat and mouse, phosphodiesterase I is
      associated with the brush borders of the straight portion (pars recta) of the
      proximal tubule, whereas inositol 1:2-cyclic phosphate 2-phosphohydrolase and
      probably glycerylphosphorylcholine diesterase are associated with the brush
      borders of the convoluted part of the tubule (pars convoluta).

PMID- 4353089
TI  - Heterogeneous distribution of glucose 6-phosphatase in rat liver microsomal
      fractions as shown by adaptation of a cytochemical technique.
AB  - 1. A novel technique for the subfractionation of rat liver smooth and rough
      microsomal fractions according to their content of glucose 6-phosphatase is
      described. This technique, based on the Gomori lead histochemical procedure,
      involves incubation of smooth and rough microsomal fractions with low
      concentrations of Pb(NO(3))(2) and glucose 6-phosphate. Control experiments, in
      which enzyme was assayed in the presence of various amounts of Pb(NO(3))(2) or in
      which microsomal fractions were reisolated after incubation with low
      concentrations of Pb(NO(3))(2) and glucose 6-phosphate, showed that lead does not
      interfere with glucose 6-phosphatase activity. 2. Discontinuous sucrose-density
      gradient centrifugation of microsomal fractions which had previously been
      incubated with various amounts of Pb(NO(3))(2) and glucose 6-phosphate showed
      that it is possible to subfractionate both smooth- and rough-microsomal fractions
      into several bands, owing to a differential modification of the density of the
      microsomal vesicles by the trapping of lead phosphate within them. 3. When the
      material in the bands obtained by density-gradient centrifugation of incubated
      microsomal fractions was assayed for glucose 6-phosphatase activity, it was found
      that the modification of the density of the microsomal fractions was directly
      related to their relative enrichment in glucose 6-phosphatase activity. Control
      experiments, in which microsomal fractions were incubated with Pb(NO(3))(2) and
      glucose 6-phosphate and then treated with EDTA, showed that the subfractionation
      was not due to aggregation of microsomal vesicles, lead and glucose 6-phosphate.
      Thus the resolution of microsomal preparations into subfractions with different
      glucose 6-phosphatase activities is interpreted as indicating heterogeneity of
      glucose 6-phosphatase distribution in the microsomal vesicles. 4. Electron
      micrographs of both smooth- and rough-microsomal subfractions show deposits of
      lead phosphate within the microsomal vesicles. The frequency and extent of these
      deposits correlate with the different amounts of glucose 6-phosphatase activity
      measured biochemically. 5. The nature of the heterogeneous distribution of
      glucose 6-phosphatase is discussed and the more general applicability of the
      technique for studying membrane fractions containing a heterogeneous distribution
      of phosphatases is indicated.

PMID- 4353090
TI  - Studies on the biosynthesis of cytochrome c.
AB  - A soluble cytochrome was isolated and purified from the slime mould Physarum
      polycephalum and identified as cytochrome c by room-temperature and low
      temperature (77 degrees K) difference spectroscopy. A close similarity between P.
      polycephalum and mammalian cytochromes c was suggested by a comparison of the
      initial rates of oxidation of both proteins by mammalian mitochondria. This
      similarity was further emphasized by redox titrations and gel-electrophoretic
      studies which indicated that P. polycephalum cytochrome c has an oxidation
      reduction midpoint potential of +257mV at pH7.0 and a molecular weight of 12500+/
      1500 (mean+/-maximum deviation for a set of six measurements). P. polycephalum
      exhibits an absolute requirement for protohaemin for growth. The (59)Fe-labelled
      haemin was prepared by chemical synthesis from protoporphyrin. The purified
      product had a specific radioactivity of 0.8+/-0.02muCi/mol. Growth of P.
      polycephalum in the presence of [(59)Fe]haemin resulted in the incorporation of
      (59)Fe into the plasmodial cytochrome c. The specific radioactivity of the
      cytochrome c haem was 0.36+/-0.02muCi/mol. The high specific radioactivity of the
      cytochrome haem indicates that synthesis of the holoenzyme must proceed by direct
      attachment of haem to the apoprotein rather than by the intermediate formation of
      a protoporphyrinogen-apoprotein complex. The observed decrease in the specific
      radioactivity of the haem group is attributed to exchange of the (59)Fe with
      unlabelled iron in the plasmodia either before or during attachment of the haem
      group to the apoprotein.

PMID- 4353091
TI  - The pattern of methylated purines formed in DNA of intact and regenerating liver
      of rats treated with the carcinogen dimethylnitrosamine.

PMID- 4353092
TI  - The synthesis of DNA associated with the nuclear membrane of guinea pig adrenal
      cells.

PMID- 4353093
TI  - An investigation of the phosphoprotein of the bovine dentin matrix.

PMID- 4353094
TI  - Protein hydrophobicity and lipid--protein interaction.

PMID- 4353095
TI  - The interrelationships between vitamin D parathyroid hormone and calcitonin.

PMID- 4353096
TI  - Some indicators of myocardial metabolism in complications caused by heterogeneous
      blood transfusion.

PMID- 4353097
TI  - The ATP pool in Escherichia coli K 12 strains bearing the R1 plasmid.

PMID- 4353098
TI  - Effect of contraceptive suture on biochemical composition of uterine fluid of
      protein deficient rats.

PMID- 4353099
TI  - Pregnant donkey's serum-induced ovulation in immature mice.

PMID- 4353100
TI  - Isolation of enteroviruses from sheep.

PMID- 4353101
TI  - Effects of some divalent cations on sympathetic ganglion function.

PMID- 4353102
TI  - Release of enzymes from a rat liver lysosome fraction: inhibition by
      catecholamines and cyclic3', 5'-adenosine monophosphate, stimulation by
      cholinergic agents and cyclic 3', 5'-guanosine monophosphate.

PMID- 4353103
TI  - [Our experience in the treatment of parotid gland neoplasms].

PMID- 4353105
TI  - Biochemical aspects concerning adenine nucleotides and some related enzymes in
      the concomitant action of cephalin and serotonin of the blood platelets.

PMID- 4353106
TI  - [A series of 17 cases of acute bacterial meningitis observed in a non-specialized
      unit].

PMID- 4353104
TI  - [Azathioprine and hepatic functional structures (clinical and experimental
      studies)].

PMID- 4353107
TI  - [Attempt to determine morbidity causing absenteeism in an active population].

PMID- 4353108
TI  - [Bronchial dilatations and bronchial tumor with granulous cells. Apropos of
      Kartagener's syndrome].

PMID- 4353109
TI  - [2 new cases of septicemia due to Campylobacter fetus].

PMID- 4353111
TI  - [A series of 14 cases of Klebsiella pneumoniae septicemia observed in a general
      medical unit].

PMID- 4353110
TI  - [Non-puerperal infections, without hemolysis or anuria due to Welchia
      perfringens. Apropos of 7 cases].

PMID- 4353112
TI  - [Respiratory manifestations of Gougerot-Sjogren syndrome].

PMID- 4353113
TI  - [Amyloid neuropathy with osteonecrosis of the medial tibial condyle].

PMID- 4353115
TI  - [Remarks on abortion].

PMID- 4353114
TI  - [Hypercalcemia and thiazides].

PMID- 4353116
TI  - [Hemoptysis revealing adrenal gland cancer with fibrinolytic activity].

PMID- 4353117
TI  - [A case of mucosal diaphragm of the lower 3d of the esophagus].

PMID- 4353118
TI  - [40 cases of primary lung abscess in adults studied in a 5 to 10 year follow-up].

PMID- 4353119
TI  - [Thyroid index method in clinical diagnosis of thyrotoxicosis].

PMID- 4353121
TI  - [Role of the duodenum in insulin secretion].

PMID- 4353120
TI  - [Urinary excretion of catecholamines and vanilmandelic acid in spasmophilia:
      statistical analysis of 77 samples].

PMID- 4353122
TI  - [Cecal plasmocytosarcoma appearing after 4 years of development of multiple
      myeloma].

PMID- 4353123
TI  - [Management of myocardial infarct during the initial period ("pre-hospital"
      phase)].

PMID- 4353124
TI  - [Ocular contusions].

PMID- 4353125
TI  - [Manifestations of the hypercalcemic syndrome].

PMID- 4353126
TI  - [Arterial hypertension in adults with congenital segmental renal hypoplasia].

PMID- 4353128
TI  - [Recurrent purulent meningitis].

PMID- 4353129
TI  - [Biliary ileus].

PMID- 4353127
TI  - [Acute hemolytic anemia with methemoglobinemia due to phenacetin: a case].

PMID- 4353130
TI  - [Hypothyroid myopathy: ultrastructural study].

PMID- 4353131
TI  - [Removal of 48 kidneys from subjects with brain death].

PMID- 4353132
TI  - [Myoblastomyoma of the maxilla in a newborn].

PMID- 4353134
TI  - A modified pancreaticoduodenectomy.

PMID- 4353135
TI  - [Australia antigen and its significance in the etiology and pathogenesis of acute
      and chronic diseases of the liver].

PMID- 4353136
TI  - [Negative inotropic effect of antiarrhythmic agents: effect of lidocaine on
      myocardial adenylate cyclase].

PMID- 4353133
TI  - The origin, hormonal nature, and action of hepatotrophic substances in portal
      venous blood.

PMID- 4353137
TI  - [Experimental studies on the Sabin-Feldmann test in mouse virus leukemias].

PMID- 4353138
TI  - [Measurement of steroid excretion in rats during ACTH administration for the
      induction of experimental atheromatosis].

PMID- 4353139
TI  - [Mechanism of action of insulin in adipose tissue: antagonism between insulin and
      lipolytic hormones in the adenyl cyclase activation system].

PMID- 4353140
TI  - Some functional aspects of the plasma apolipoproteins.

PMID- 4353141
TI  - [Early diagnosis of familial hyperlipoproteinemia type II (umbilical cord blood
      beta cholesterol)].

PMID- 4353142
TI  - [Incorporation of 4-14C-cholesterol into cholesterol ester fractions of HDL, LDL
      and VLDL in liver cirrhosis].

PMID- 4353143
TI  - [Significance of nicotinic acid amide for the biosynthesis of NAD in the isolated
      perfused rat liver].

PMID- 4353144
TI  - [Stimulation and suppression of angiotension I and II in arterial hypertension].

PMID- 4353145
TI  - [Exact measurement of subnormal renin concentrations in primary aldosteronism
      using radioimmunologic demonstration of angiotension I].

PMID- 4353146
TI  - Renin-angiotensin in extrarenal tissues.

PMID- 4353147
TI  - [Functional diagnosis of the hypothalamo-hypophyseal-adrenal system using
      radioimmunologic ACTH determination].

PMID- 4353148
TI  - [In-vitro and in-vivo studies on the effect of hyperthermia on malignant
      neoplasms and normal tissues].

PMID- 4353149
TI  - [Quantitative determination of ifosfamide and an ifosfamide metabolite in the
      human urine].

PMID- 4353150
TI  - [Collagen proline hydroxylase; proenzyme, activation mechanisms and clinical
      significance].

PMID- 4353152
TI  - [Effect of highly purified D-thyroxine ("Dyno") in hyperlipoproteinemias type II
      a and II b].

PMID- 4353151
TI  - [Therapy of hyperlipoproteinemias type II a and II b using dextro-thyroxine or
      D,L-alpha-methyl-thyroxine-ethylester].

PMID- 4353153
TI  - [Experiences with single high dosage iphosphamide therapy in metastasizing
      malignant neoplasms].

PMID- 4353155
TI  - [Immune reaction to neoplasm antigens].

PMID- 4353154
TI  - [Molecular endocrinology].

PMID- 4353157
TI  - [Significance of the Epstein-Barr virus and cytomegalovirus antibody
      demonstration in the diagnosis of infectious mononucleosis].

PMID- 4353156
TI  - [Demonstration of cytomegalovirus antibodies in Australia-antigen-positive and
      Australia-antigen-negative hepatitis].

PMID- 4353159
TI  - Effects of different hormones on the zoning and sinusoids of the adrenal gland.

PMID- 4353158
TI  - Ultrastructural studies on cell degeneration in the mouse uterovaginal anlage.

PMID- 4353160
TI  - The actions of cyclic nucleotides on the toad bladder.

PMID- 4353161
TI  - Regulation of gene transcription in Escherichia coli by cyclic AMP.

PMID- 4353162
TI  - Role of cyclic AMP in the action of neurohypophyseal hormones on kidney.

PMID- 4353164
TI  - Role of cyclic AMP in the regulation of gastric secretion in dogs and humans.

PMID- 4353165
TI  - The effect of cholera toxin on intestinal adenyl cyclase.

PMID- 4353163
TI  - The role of cyclic AMP in the control of fluid secretion.

PMID- 4353166
TI  - Cyclic AMP and vascular smooth muscle.

PMID- 4353167
TI  - Cyclic AMP as a first messenger.

PMID- 4353168
TI  - Studies on the possible role of cyclic AMP in drug-induced coronary
      vasodilatation.

PMID- 4353169
TI  - Role of cyclic AMP and Ca++ in metabolic and mechanical events in smooth muscle.

PMID- 4353170
TI  - Role of cyclic AMP in platelet function.

PMID- 4353171
TI  - The positive inotropic effect of cyclic AMP.

PMID- 4353172
TI  - The role of cyclic AMP in the inotropic response to isoprenaline and glucagon.

PMID- 4353173
TI  - Effect of dibutyryl cyclic GMP on cultured beating rat heart cells.

PMID- 4353174
TI  - Inotropic and chronotropic effects of dibutyryl cyclic AMP.

PMID- 4353175
TI  - The role of cyclic AMP in visual excitation.

PMID- 4353176
TI  - On the mechanism of action of cyclic AMP and its role in synaptic transmission.

PMID- 4353178
TI  - Neuroendocrine control of the cyclic AMP system of brain and pineal gland.

PMID- 4353177
TI  - Cyclic AMP-dependent protein kinases from skeletal muscle and liver.

PMID- 4353179
TI  - Regulation of cyclic AMP metabolism in cultured cells of the nervous system.

PMID- 4353180
TI  - Cyclic AMP-mediated adrenergic synapses to cerebellar Purkinje cells.

PMID- 4353181
TI  - Cyclic AMP in the rat brain: microwave irradiation as a means of tissue fixation.

PMID- 4353182
TI  - Regulation of brain phosphodiesterase activity: Ca++ plus Mg++ -dependent
      phosphodiesterase and its activating factor from rat brain.

PMID- 4353184
TI  - The role of cyclic AMP in activation of hormone-sensitive lipase of adipose
      tissue.

PMID- 4353183
TI  - Prostaglandin--adenyl cyclase relationships.

PMID- 4353185
TI  - Cyclic AMP and prostaglandins in hormone action.

PMID- 4353186
TI  - Functional relations between cyclic AMP, prostaglandins, and luteinizing hormone
      in rat pituitary and ovary.

PMID- 4353187
TI  - A study of the bioloical activity and resistance to phosphodiesterase of some
      derivatives and analogues of cyclic AMP.

PMID- 4353188
TI  - The role of cyclic AMP in lysosome mobilization and their nucleotropic
      translocation in steroid hormonal target cells.

PMID- 4353190
TI  - Levels of cyclic AMP and rate of fat mobilizing lipolysis in human adipose tissue
      in response to different adrenergic stimulators.

PMID- 4353189
TI  - Studies on the role of cyclic AMP in human lipolysis.

PMID- 4353191
TI  - The role of cyclic AMP in the control of hepatic glucose production by glucagon
      and insulin.

PMID- 4353192
TI  - Determination of alpha-quartz in the respirable portion of airborne particulates
      by X-ray diffraction.

PMID- 4353193
TI  - Immunologic properties of ferritin.

PMID- 4353196
TI  - [Ribonucleic acid and protein metabolism following infection of chick embryo
      cells with vesicular stomatitis virus: studies with thermosensitive mutants].

PMID- 4353195
TI  - The functional significance of surface structures on lymphocytes.

PMID- 4353194
TI  - Animal model of human disease. Liver cell carcinoma, hepatocellular carcinoma,
      hepatoma.

PMID- 4353197
TI  - [Circulating toxin, an aid in the diagnosis of type B botulism in man].

PMID- 4353198
TI  - Muscular tumors of the stomach: clinical and pathological study of 113 cases.

PMID- 4353199
TI  - Hepatic arterial patency and complications after catheterization for infusion
      chemotherapy.

PMID- 4353200
TI  - [Isolation of hydrolysis products from the glomerular basal membrane of rats
      after clostridiopeptidase A action].

PMID- 4353201
TI  - [Transcription of the adenovirus genome: early proteins and transcription of the
      viral DNA].

PMID- 4353202
TI  - [Description of structures analogous to the Annulate lamellae in normal or
      pathological cells of the human and rat exocrine pancreas].

PMID- 4353203
TI  - [Temporary suppression of the quaternary structure of plasma alphalipoproteins
      (HDL) in the early stage of common viral hepatitis].

PMID- 4353204
TI  - [Inhibition of interferon activity by ouabain].

PMID- 4353205
TI  - Abdominal aortography in the newborn via the umbilical artery.

PMID- 4353206
TI  - Murine erythroblastosis by a novel viral agent.

PMID- 4353207
TI  - Chemotherapy of lymph node metastasis by thigh and footpad inoculation of mouse
      leukemia L-1210 cells.

PMID- 4353208
TI  - Molecular weight of cytochrome oxidase.

PMID- 4353210
TI  - Temperature-sensitive mutants of vesicular stomatitis virus; homology and
      nomenclature.

PMID- 4353209
TI  - A rabies-induced serum factor inhibiting Rous sarcoma virus in chicks.

PMID- 4353211
TI  - Host range conversion of the murine sarcoma-leukaemia complex.

PMID- 4353212
TI  - The role of antibody and host cells in the resistance of mice against infection
      by coxsackie B-3 virus.

PMID- 4353213
TI  - Evidence for a group protein in foot-and-mouth disease virus particles.

PMID- 4353214
TI  - Haemagglutination by type SAT 2 foot-and-mouth disease viruses.

PMID- 4353215
TI  - Properties of mouse embryo cells infected with murine sarcoma virus and simian
      virus 40 simultaneously in vitro.

PMID- 4353216
TI  - Restoration of the fusion activity of L cell-borne Sendai virus by trypsin.

PMID- 4353217
TI  - Primary carcinoma of the liver: a study of 282 cases in Ugandan Africans.

PMID- 4353218
TI  - Actions of 1,25-dihydroxycholecalciferol in patients with hypophosphatemic,
      vitamin-D-resistant rickets.

PMID- 4353219
TI  - Familial hypophosphatemia: the dilemma of treatment.

PMID- 4353220
TI  - [Scintigraphy with Se-75 Na selente in brain tumors and cardiovascular attacks].

PMID- 4353222
TI  - Metabolism of the myocardium at cellular level.

PMID- 4353221
TI  - Time course of decrease in blood pressure and in blood pressure response to
      vasopressor agents during pregnancy in the rat.

PMID- 4353223
TI  - The role of diet in the management of hyperlipoproteinaemias.

PMID- 4353225
TI  - Delay in bone age in children with cyanotic congenital heart disease.

PMID- 4353224
TI  - Ventilatory pumping of human pulmonary lymphatic vessels.

PMID- 4353226
TI  - Use of ultrasonography to follow regression of theca lutein cysts.

PMID- 4353227
TI  - [Pigmented villo-nodular synovitis. Apropos of 4 cases].

PMID- 4353228
TI  - Granuloma formation.

PMID- 4353230
TI  - [Relationship between neurotically induced hypertension and the contents of
      pancreatic B-cell granules in albino rats].

PMID- 4353231
TI  - [The pathogenetic significance of "autoantibodies" in the NZB-W-F1 hybrids. II.
      Morphological studies].

PMID- 4353229
TI  - Contraception.

PMID- 4353232
TI  - Suppression of the defect in cell division in the histidine regulatory mutants of
      Salmonella typhimurium.

PMID- 4353233
TI  - A case of juvenile angiofibroma.

PMID- 4353234
TI  - The amino acid sequence of cytochrome c from Nigella damascena L. (love-in-a
      mist).
AB  - The amino acid sequence of cytochrome c from Nigella damascena L. was determined
      on 0.2mumol of protein. Peptides from a single chymotryptic digest were analysed
      by the dansyl-Edman procedure. These peptides were ordered by reference to the
      sequences of other plant cytochromes c, assuming that the Nigella cytochrome is
      homologous with the other cytochromes. Many of the Nigella peptides were one or
      two residues short when compared with the corresponding chymotryptic peptides
      from other plant cytochromes c. These residues are assumed to have been removed
      by an endogenous carboxypeptidase, and the identification and placing of these
      residues is entirely based on homology. These residues are numbered 3, 18, 42,
      43, 44, 54, 67, 72, 73, 82 and 105. A number of other positions are almost
      entirely placed by homology. These are positions which could not be placed
      definitely by dansyl-Edman analysis or by dansylation after digestion with
      carboxypeptidase A, and are numbered 14, 15, 16, 39, 40, 85, 86, 87 and 88.
      Except for residue 15, all residues based entirely, or nearly so, on homology
      have been previously found invariant in sequences of plant cytochromes c.
      Experimental details are given in a supplementary paper that has been deposited
      as Supplementary Publication SUP 50017, at the National Lending Library for
      Science and Technology, Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies can
      be obtained on the terms indicated in Biochem. J. (1973) 131, 5.

PMID- 4353235
TI  - The formation of a  -(1 leads to 4)-D-galactan chain catalysed by a Phaseolus
      aureus enzyme.
AB  - With a particulate enzyme preparation from Phaseolus aureus hypocotyls, UDP-alpha
      d-[U-(14)C]galactose served as a precursor for a number of products. One of these
      products was characterized as a beta-(1-->4)-linked galactan. The ADP-, GDP-, TDP
      and CDP- derivatives of alpha-d-galactose did not serve as biosynthetic
      precursors for any products insoluble in 70% ethanol, nor as substrates for a
      sugar nucleotide 4-epimerase which is present in the particulate enzyme
      preparation. The (14)C-labelled beta-(1-->4)-galactan is alkali-insoluble and was
      characterized by analysis of partial acetolysis products. The labelling pattern
      of the [(14)C]oligosaccharides derived from acetolysis indicates that (1) only
      slightly more than two [(14)C]galactose moieties are added to the growing
      polysaccharide chain on average, and (2) these additions take place at the
      reducing end of the polysaccharide chain. The radioactive beta-(1-->4)-linked
      galactan chain represented 8.5% of the radioactivity initially added, and 20% of
      the water- and butanol-insoluble products derived from UDP-alpha-d
      [(14)C]galactose. Total hydrolysis of the alkali-insoluble fraction of Phaseolus
      aureus hypocotyl yielded d-glucose and d-mannose in a 5:1 ratio but no detectable
      quantities of d-galactose. A trace quantity of a radioactive disaccharide,
      identified as (1-->3)-linked galactobiose, was isolated from the partial
      acetolysate of the alkali-insoluble [(14)C]polysaccharide material. Also isolated
      from this partial acetolysate was a C-1 derivative of [(14)C]galactose, which
      could not be identified. An alkali-soluble galactose-containing polysaccharide
      was also synthesized in this enzymic reaction, and represented 20% of the water-
      and butanol-insoluble products derived from UDP-alpha-d-[(14)C]galactose. The
      spectrum of radioactive oligosaccharides produced by partial acetolysis of this
      alkali-soluble polysaccharide material was different from that obtained from the
      alkali-insoluble polysaccharide, indicating a different structure.

PMID- 4353236
TI  - The association between phosphatidylinositol phosphodiesterase activity and a
      specific subunit of microtubular protein in rat brain.
AB  - 1. Supernatant proteins from rat brain were separated into two fractions
      containing phosphatidylinositol phosphodiesterase activity by chromatography on
      DEAE-Sephadex A-50. 2. The first fraction sediments in linear sucrose density
      gradients in two bands corresponding to molecular weights of 66000 and 36000.
      There was presumptive evidence that the lighter protein constituted the monomeric
      form of the enzyme. The second fraction sediments predominantly as a single
      protein of molecular weight 86000. 3. Treatment of rat brain supernatant with
      [(3)H]colchicine abolished the second DEAE-Sephadex peak and removed the lighter
      protein from the first peak. These proteins emerged in the same position as the
      protein binding [(3)H]colchicine at high salt concentration; phospholipase
      activity was recovered from linear sucrose density gradients in positions
      corresponding to molecular weights 88000 and 43000, together with an aggregate of
      molecular weight 140000. Electrophoresis on sodium dodecyl sulphate-urea
      polyacrylamide gels of this fraction revealed only three proteins: the alpha and
      beta-subunits of microtubular protein, of molecular weights 56000 and 52000
      respectively, and a protein of molecular weight 38000. 4. A sample of
      microtubular protein from mouse, labelled in vivo with [(3)H]proline and
      (32)P(i), was added to rat brain supernatant together with an equal amount of the
      same microtubular protein treated with cyclic AMP and [gamma-(32)P]ATP and the
      mixture subsequently characterized by ion-exchange chromatography. Some
      phospholipase activity characteristic of the second peak from DEAE-Sephadex was
      associated with one fraction of added microtubular protein. This fraction was
      identified on the basis of the (3)H:(32)P ratio as the beta subunit of the
      protein treated with ATP and cyclic AMP. The subunit of added microtubular
      protein untreated with nucleotides was not associated with phospholipase
      activity.

PMID- 4353237
TI  - A collagenase in extracts of the invertebrate Bipalium kewense.
AB  - The localization, isolation and partial characterization of a collagenolytic
      enzyme from the land planarian Bipalium kewense is described. This enzyme can be
      obtained by direct extraction of the organism, and can be separated from non
      collagenous proteolytic activity by (NH(4))(2)SO(4) precipitation and Sephadex
      gel chromatography. Its mode of attack on collagen and sensitivity to a variety
      of inhibitors indicate that this enzyme differs from vertebrate collagenases and
      a previously described invertebrate collagenase.

PMID- 4353239
TI  - Lack of temperature-sensitivity of rat liver pyruvate kinase.
AB  - Rat liver pyruvate kinase, prepared by Sephadex treatment of a 10(5)g supernatant
      in phosphate buffer, is quite stable and gives reproducible results when a
      variety of parameters are altered in the enzyme assay. Incubation of this
      preparation at 25 degrees C or 0-2 degrees C has no effect on the activation by
      fructose 1,6-diphosphate or inhibition by ATP or alanine.

PMID- 4353238
TI  - A comparaive study of the effects of chemical modification on the immunochemical
      and optical properties of human plasma low-density lipoprotein(s) and
      apoproteins.
AB  - 1. The structure of human plasma low-density lipoprotein(s) [LD lipoprotein(s)]
      was investigated by several immunological and optical techniques. The effects of
      delipidation and of chemical modification by 3-carboxypropionylation,
      acetylation, diazotization and amidination were examined. A sensitive double
      antibody radioimmunoassay for human LD lipoproteins is presented and is used to
      assess the extent of immunochemical modification. A computer best-fit analysis is
      used to analyse circular-dichorism (c.d.) spectra. These methods permit
      comparisons of the relative effects of chemical modification and delipidation of
      LD lipoprotein under similar experimental conditions. 2. 3-Carboxypropionylation,
      acetylation or diazotization produces qualitative and quantitative changes in the
      immunochemical properties of LD lipoprotein. Amidination causes minor changes
      detected by radioimmunoassay but not by double-diffusion experiments. In general,
      the order of effectiveness in displacing (125)I-labelled LD lipoprotein is
      amidinated>diazo or acetyl>3-carboxypropionyl derivatives. 3. The order of the
      extent of conformational alteration induced in apoLD lipoprotein and LD
      lipoprotein, as judged by c.d. analyses, was 3
      carboxypropionylation>diazotization>acetylation or amidination. 4. Delipidation
      of LD lipoprotein results in immunological alterations that are qualitatively
      detected by antisera to LD lipoprotein. Four of five antisera to apoLD
      lipoprotein form precipitin lines of identity between native LD lipoprotein and
      apoLD lipoprotein in double-diffusion experiments. An anti-(apoLD lipoprotein)
      serum that forms precipitin lines of complete identity between LD lipoprotein and
      apoLD lipoprotein reacts differently with these two antigens in radioimmunoassay.
      ApoLD lipoprotein is only one-fourth to one-half as effective as LD lipoprotein,
      on a protein basis, in the displacement of (125)I-labelled LD lipoprotein from
      this anti-(apoLD lipoprotein). 5. Conformational analysis indicates that apoLD
      lipoprotein retains a high proportion of the structural integrity of the native
      lipoprotein. Delipidation induces a small decrease in the content of beta
      structure and a small increase in disordered structure, without greatly affecting
      the alpha-helical content. Chemical modification produces more severe
      conformational changes of apoLD lipoprotein than of LD lipoprotein. Computer
      analysis of the c.d. spectra of apoLD lipoprotein indicates that addition of high
      concentrations of sodium decyl sulphate abolishes most of the beta-conformation
      concomitant with increases in alpha-helical and disordered structure. 6. There is
      parallelism between the alteration of the charge of LD lipoprotein and apoLD
      lipoprotein and the extent of immunochemical and conformational changes.

PMID- 4353240
TI  - A radiographic survey of monumental masonry workers in Aberdeen.

PMID- 4353241
TI  - The effects of pargyline on overflow of transmitter and uptake of noradrenaline
      in the cat spleen.
AB  - 1. Twenty minutes after the addition of pargyline (5 x 10(-4)M) to blood
      perfusing the isolated spleen of the cat, the overflow of transmitter resulting
      from stimulation of the sympathetic nerves increased 2.3-3-fold. Lower doses of
      pargyline did not significantly affect overflow.2. Monoamine oxidase activity,
      measured with either radioactively labelled tyramine or noradrenaline as
      substrate, was almost completely inhibited by doses of pargyline in the range of
      10(-4)M to 5 x 10(-4)M. Inhibition of enzyme activity was not correlated with the
      effect on overflow. Pargyline had only a slight inhibitory effect on catechol-O
      methyl transferase.3. Uptake of a 1 mug injection (pulse) of labelled
      noradrenaline, following pargyline (5 x 10(-4)M), was increased to 199.1% of that
      found in control experiments.4. Pargyline significantly reduced the vascular
      responses to nerve stimulation but had no significant effect on capsular
      responses.5. The inhibitor had no effect on resting overflow of labelled
      noradrenaline from the spleen but doubled the overflow of labelled noradrenaline
      following nerve stimulation.6. It is suggested that the effect of pargyline on
      overflow is due to increased release of transmitter during nerve stimulation.7.
      The possible clinical significance of these findings is discussed.

PMID- 4353243
TI  - Does methaqualone cause neuropathy?

PMID- 4353242
TI  - Effect of phospholipase C on calcium release from epithelia treated with
      antidiuretic hormone.
AB  - 1. Addition of antidiuretic hormone (ADH) to the bladders of toads (Bufo marinus)
      preloaded with (45)Ca causes an increase in the rate of calcium efflux.2.
      Pretreatment of the serosal surfaces of bladders with phospholipase C prevents
      the action of ADH on calcium efflux.

PMID- 4353244
TI  - Smooth muscle autoantibodies in infectious mononucleosis.
AB  - Smooth muscle antibodies (S.M.A.) were found in the sera of 81% of 126 patients
      over 10 years old with seropositive infectious mononucleosis tested within one
      month of onset. In 27 patients presenting clinically with infectious
      mononucleosis but having negative Paul-Bunnell tests the incidence of S.M.A. was
      44%. In children 10 years of age or less in these two categories S.M.A. were
      present in 75% and 25% respectively, while in children of similar age not
      suspected of having infectious mononucleosis the incidence of S.M.A. was 10%.
      Among 45 adults with past histories of seropositive infectious mononucleosis more
      than one year before the incidence of S.M.A. was 33%, in contrast to 14% in 98
      subjects with a negative history for infectious mononucleosis.

PMID- 4353245
TI  - [Experiences with 200 total gastrectomies for gastric carcinoma].

PMID- 4353246
TI  - [Experimental reproduction of the inclusions of metachromatic leucodystrophy
      using an overload of sulfatides of sulfatase deficient fibroblasts].

PMID- 4353247
TI  - [Protein kinase activity associated with the vesicular stomatitis virus (VSV)].

PMID- 4353248
TI  - [X-ray diffraction study of metastable states and hysteresis cycles of DNA].

PMID- 4353250
TI  - Effect of sex hormones on the activity of protein kinases in rat ventral prostate
      and uterus.

PMID- 4353249
TI  - Dextran-coated charcoal technique to make the hormone-free serum as a diluent for
      standard curve of radioimmunoassay.

PMID- 4353251
TI  - Effects of ACTH and its synthetic analogues on water balance in rats.

PMID- 4353252
TI  - Improvement by exogenous cyclic AMP of hereditary vasopressin-resistant diuresis
      in mice with normal adenyl cyclase system of the kidney cells.

PMID- 4353253
TI  - Study on the systematic use of serial estimation of human placental lactogen
      (hPL) and human chorionic gonadotropin (hCG) for the management of trophoblastic
      neoplasia.

PMID- 4353254
TI  - Operantly conditioned firing patterns of epileptic neurons in the monkey motor
      cortex.

PMID- 4353255
TI  - Acoustic responses and plasticity of limbic units in cats.

PMID- 4353257
TI  - Spontaneous and evoked bioelectric activity in organized cerebellar tissue
      cultures.

PMID- 4353256
TI  - Intrinsic connections of caudate neurons. Locally evoked intracellular responses.

PMID- 4353258
TI  - Recruitment of motor units in voluntary contraction of a finger muscle in man.

PMID- 4353259
TI  - Firing rate of individual motor units in voluntary contraction of abductor digiti
      minimi muscle in man.

PMID- 4353260
TI  - [Plasma aldosterone levels in primary aldosteronism. 1. Renin-angiotensin system
      and aldosterone].

PMID- 4353261
TI  - [Urinary 6beta-hydroxycortisol. II. Urinary 6beta-hydroxycortisol in different
      diseases and after administration of drugs].

PMID- 4353262
TI  - [Renin-angiotensin-aldosterone system in hyperthyroidism].

PMID- 4353264
TI  - [Preparation and after care in endoscopic examinations].

PMID- 4353263
TI  - [Paradoxical binding phenomenon in radioimmunoassay of ACTH].

PMID- 4353265
TI  - [Primary liver tumors in childhood].

PMID- 4353266
TI  - Formation and decomposition of pyrophosphate related to bacterial
      photophosphorylation.

PMID- 4353267
TI  - The inhibition mechanism of the cytochrome oxidase reaction. IV. The nature of
      the kinetically inactive complex of cytochrome oxidase with cyanide.

PMID- 4353268
TI  - Role of oleate in the regulation of "neutral" rabbit liver fructose 1,6
      diphosphatase activity.

PMID- 4353269
TI  - Interaction between adenosine triphosphate and glyceraldehyde 3-phosphate
      dehydrogenase. 3. Mechanism of action and metabolic control of the enzyme under
      simulated in vivo conditions.

PMID- 4353270
TI  - Regulation of glyceraldehyde 3-phosphate dehydrogenase by phosphocreatine and
      adenosine triphosphate. IV. Factors affecting in vivo control of enzymatic
      activity.

PMID- 4353271
TI  - Effect of beta-adrenergic catecholamines on sodium transport in turkey
      erythrocytes.

PMID- 4353272
TI  - L-Glycerol 3-phosphate dehydrogenases. II. Effects of phosphorylated compounds on
      nicotinamide adenine dinucleotide linked enzyme from rabbit liver.

PMID- 4353273
TI  - Specific binding of phosphorylated non-histone chromatin proteins to
      deoxyribonucleic acid.

PMID- 4353274
TI  - Inactivation of melanocyte-stimulating hormone release-inhibiting factor by a
      manganese-stimulated bovine brain aminopeptidase.

PMID- 4353275
TI  - Arginase isozymes of rat mammary gland, liver, and other tissues.

PMID- 4353276
TI  - Expression of the mitochondrial genome in HeLa cells. XVII. Heterogeneity of
      isolated HeLa cell mitochondria as assayed for their enzymatic and in vivo
      biosynthetic activities.

PMID- 4353277
TI  - Plasma membrane cyclic adenosine 3':5'-monophosphate phosphodiesterase of
      cultured cells and its modification after trypsin treatment of intact cells.

PMID- 4353279
TI  - Early events in glucocorticoid action. Activation of the steroid receptor and its
      subsequent specific nuclear binding studied in a cell-free system.

PMID- 4353278
TI  - Partial resolution of the enzymes catalyzing oxidative phosphorylation. XXXIX.
      Reconstitution of the third segment of oxidative phosphorylation.

PMID- 4353280
TI  - Nature of nuclear acceptor sites for glucocorticoid- and estrogen-receptor
      complexes.

PMID- 4353281
TI  - Neuroendocrine responses to physical and psychological stress.

PMID- 4353282
TI  - Recruitment deafness: functional effect of priming-induced audiogenic seizures in
      mice.

PMID- 4353283
TI  - Genetic and enzymatic characterization of a conditional lethal mutant of
      Escherichia coli K12 with a temperature-sensitive DNA ligase.

PMID- 4353284
TI  - Genetics and function of DNA ligase in Escherichia coli.

PMID- 4353285
TI  - [Mechanism of muscular contraction and its regulation].

PMID- 4353286
TI  - Spontaneous skin potential responses during natural sleep in monkeys.

PMID- 4353287
TI  - Interferon production by Bordetella pertussis components in rabbits and in rabbit
      cell cultures.

PMID- 4353288
TI  - Chronic lead nephropathy.

PMID- 4353289
TI  - [Degenerative changes in the fine structure of the orbicularis oculi muscle].

PMID- 4353291
TI  - Incorporation of (1-14c)-oleic acid into neutral glycerides and phosphoglycerides
      of mouse brain.

PMID- 4353292
TI  - Molecular conformation of guanosine 3,'5-cyclic monophosphate.

PMID- 4353293
TI  - Post-tetanic potentiation and facilitation do not share a common calcium
      dependent mechanism.

PMID- 4353290
TI  - Preferential labeling of phosphatidylcholine during phospholipid synthesis by
      bovine mammary tissue.

PMID- 4353294
TI  - [Wallenberg's syndrome in late radiation injury of the medulla oblongata].

PMID- 4353295
TI  - [Hepatic synthesis of alpha-1-feto protein. Immunofluorescent study of a case of
      juvenile cirrhosis].

PMID- 4353296
TI  - [Acute epidemic hemorrhagic conjunctivitis due to an enterovirus].

PMID- 4353297
TI  - Windowless semiconductor radiation detectors for measurement of low-energy beta
      emitters in vivo and in vitro.

PMID- 4353299
TI  - [Morphological aspects of the problem of hypophyseal regulation of the glomerular
      zone of the adrenal gland. II. Histochemistry of the adrenocortical cells of
      birds and amphibia under ACTH stimulation].

PMID- 4353298
TI  - [Effect of reserpine on the hypothalamo-hypophyseo-adrenal system of the rat in
      the prenatal and early postnatal periods].

PMID- 4353300
TI  - [Experimental data on the adrenocorticolytic activity of m,p
      1dichlorodiphenyldichloroethane and p,p-1-diethyldiphenyldichloroethane].

PMID- 4353301
TI  - Insomnia with sleep apnea: a new syndrome.
AB  - A new clinical syndrome, sleep apnea associated with insomnia, has been
      characterized. Repeated episodes of apnea occur during sleep. Onset of
      respiration is associated with general arousal and often complete awakening, with
      a resultant loss of sleep. An important clinical implication is that patients
      complaining only of insomnia may be suffering from this syndrome.

PMID- 4353302
TI  - Plasma membranes: isolation from naturally fused and lysolecithin-treated muscle
      cells.
AB  - A medium containing bicarbonate and calcium was used to isolate plasma membranes
      of cultured muscle cells. Membranes from differentiated myotubes, as well as the
      labile, largely unfused, lysolecithin-treated cells from the same culture could
      be isolated by identical manipulations. Adenylate cyclase of high specific
      activity was assayed in plasma membranes from both types of cells. Lysolecithin
      treatment apparently interferes with the metabolism and turnover of membrane
      phospholipids and thus prevents the natural fusion of muscle cells.

PMID- 4353303
TI  - Photopic suppression of monkey's rod receptor potential, apparently by a cone
      initiated lateral inhibition.

PMID- 4353304
TI  - [Conventional roentgen diagnosis of the retroperitoneal space in neoplasm after
      care].

PMID- 4353305
TI  - Ultradian rhythms in human telemetered gross motor activity.

PMID- 4353306
TI  - Circadian rhythms of free radical state concentrations in the organs of mice.

PMID- 4353307
TI  - Aftereffects of alcohol on the perception and control of pitch attitude during
      centripetal acceleration.

PMID- 4353308
TI  - Herpes zoster in children with cancer.

PMID- 4353309
TI  - Wilms tumor in right atrium.

PMID- 4353310
TI  - Six year follow-up of a child with Bartter syndrome.

PMID- 4353311
TI  - Benign nasal tumor appearing as neonatal respiratory distress. First reported
      case of nasopharyngeal fibrous histiocytoma.

PMID- 4353313
TI  - Instantaneous decompression and the skin.

PMID- 4353312
TI  - Physiological psychology: sleep.

PMID- 4353314
TI  - [UV-irradiation of the foot-and-mouth disease virus. 1. Inactivation in relation
      to the concentration and purity of the virus and quantal yield at 2537 Angstrom].

PMID- 4353315
TI  - Chinese psychiatry. A visit to a Chinese mental hospital.

PMID- 4353316
TI  - 24-Hour sleep patterns. A comparison between 2- to 3-year-old and 4- to 6-year
      old children.

PMID- 4353317
TI  - Sleep EEG studies in untreated, long-term schizophrenic patients.

PMID- 4353319
TI  - The surgical management of amoebiasis in children.

PMID- 4353320
TI  - [Pain in the area of the upper extremities and its treatment].

PMID- 4353318
TI  - Barbiturate-induced transmitter release at a frog neuromuscular junction.
AB  - 1. The influence of barbiturates on neuromuscular transmission at end-plates of
      frog sartorius muscles was investigated electrophysiologically on preparations
      bathed in Ringer solution containing a low concentration of calcium and a high
      concentration of magnesium.2. Effects of a convulsant barbiturate, 5-(2
      cyclohexylideneethyl)-5-ethyl barbituric acid (CHEB), were compared with those of
      phenobarbitone.3. CHEB and phenobarbitone increased the mean quantum content of
      the end-plate potentials and decreased the mean amplitude of the miniature end
      plate potentials.4. Both barbiturates enhanced the duration of the nerve-terminal
      action potential and had little or no effect on the effective resistance of the
      skeletal muscle membrane.

PMID- 4353321
TI  - [Determination of cyclic adenosine 3',5'-monophosphate (cAMP) in urine for the
      diagnosis of primary hyperparathyroidism].

PMID- 4353322
TI  - [Subacute cerebellar degeneration and Eaton-Lambert syndrome associated with lung
      cancer].

PMID- 4353323
TI  - [Clinical observations of unilateral lesions in the 9th, 10th, 11th, and 12th
      cranial nerves].

PMID- 4353324
TI  - Pituitary ACTH and GH content associated with the loss of acidophils following
      thyroidectomy.

PMID- 4353325
TI  - Relation between changes in the acid-base and the energy metabolism of the brain
      in hepatic coma.

PMID- 4353326
TI  - Changes in collagen with age. V. Modification of mouse skin collagen by whole
      body x-irradiation.

PMID- 4353327
TI  - [Plasma aldosterone levels in primary aldosteronism. II. Aldosterone and ACTH].

PMID- 4353329
TI  - Pathophysiology and diagnosis of tear film abnormalities. Surfacing
      abnormalities.

PMID- 4353328
TI  - Pathophysiology of human tears.

PMID- 4353330
TI  - Renal stone crystals grown in gel systems. A preliminary report.

PMID- 4353331
TI  - The sucrose-gap technique. Autonomic drugs and electrical characteristics of the
      ureter.

PMID- 4353332
TI  - Oxidation of a ferrocytochrome c in the crystalline state--structural change and
      anion binding.

PMID- 4353334
TI  - Ferredoxin-linked nitrate reductase from Clostridium perfringens.

PMID- 4353333
TI  - Inhibitory effect of Na+ on phosphorylation of proteins in brain microsomes and
      synaptic membranes.

PMID- 4353335
TI  - Combined transmission electron microscopy and X-ray micro-analysis of ultrathin
      frozen dried sections--an investigation to determine the normal elemental
      composition of mammalian tissue.

PMID- 4353336
TI  - Fluidity of phospholipid bilayers and membranes after exposure to osmium
      tetroxide and gluteraldehyde.

PMID- 4353337
TI  - Subcellular site of the phosphatidylinositol effect. Distribution on density
      gradients of labelled lipids from resting and active sympathetic ganglia of the
      rat.

PMID- 4353338
TI  - Influence of neuroleptic drugs and apomorphine on dopamine-sensitive adenylate
      cyclase of retina.

PMID- 4353339
TI  - [Susceptibility of pathogens isolated from clinical specimens to lividomycin].

PMID- 4353340
TI  - [Antibacterial activity of lividomycin against anaerobes].

PMID- 4353341
TI  - [Pharmacokinetics of antimicrobial agents. Lividomycin].

PMID- 4353342
TI  - Hexagonal arrangement of filaments in herpes simplex virus type 2-infected cells.

PMID- 4353344
TI  - Effect of angiotensin on blood pressure in normal and cirrhotic rats.

PMID- 4353343
TI  - Pharmacological study of hydroxy bis-[2-(p-chlorophenoxy)-isobutyric acid]
      aluminium. II. The effect of hydroxy bis-[2-(-chlorophenoxy)-isobutyric acid]
      aluminum on lipid metabolism in hypercholesterolimic rats.

PMID- 4353345
TI  - Pituitary-adrenal responsiveness during lactation in rats.

PMID- 4353347
TI  - [Preparation of goiters with toxic manifestations for reduction thyroidectomy.
      Value of cytochrome C].

PMID- 4353346
TI  - Postweaning development of negative feedback in the pituitary-adrenal system of
      the rat.

PMID- 4353348
TI  - Diagnostic problems of trophoblastic disease in women aged 50 or more.

PMID- 4353349
TI  - Ovarian lutein cysts in pregnancy.

PMID- 4353351
TI  - Pregnancy and delivery post radical hemipelvectomy.

PMID- 4353350
TI  - Simultaneous laparoscopy and hysteroscopy for intrauterine adhesions.

PMID- 4353352
TI  - Safety and antigenicity of temperature sensitive (TS) mutant respiratory
      syncytial virus (RSV) in infants and children.

PMID- 4353353
TI  - [The appearance of carcinomas in mice inoculated with Rous sarcoma or with RNA
      extract of the sarcoma].

PMID- 4353354
TI  - Comparative studies on the pathogenicity for mice of tumour homogenates and of
      nucleic acid extracted from chicken sarcomas induced by the Bryan strain of Rous
      sarcoma virus.

PMID- 4353355
TI  - The possibility to overcome species and age resistance in the induction of a
      neoplastic process by an avian tumour virus.

PMID- 4353356
TI  - Particularities of cytomegalovirus (CMV)-induced cytophagia.

PMID- 4353357
TI  - Photoacoustic spectroscopy of biological materials.
AB  - A new technique for performing optical spectroscopy on solids has been developed.
      Photoacoustic spectra of cytochrome c and hemoglobin show how this technique can
      be used to obtain information about optical absorptions and subsequent de
      excitations in solid biological materials, particularly those which cannot
      readily be studied by conventional means.

PMID- 4353358
TI  - Insecticide inhibition of 5alpha-dihydrotestosterone binding in the rat ventral
      prostate.
AB  - The chlorinated hydrocarbon insecticides dieldrin and o,p'-DDT inhibit binding of
      5alpha-dihydrotestosterone to specific receptor proteins in rat prostate cytosol.
      Dieldrin is less inhibitory than o,p'-DDT.

PMID- 4353359
TI  - Murine C-type RNA virus from spontaneous neoplasms: in vitro host range and
      oncogenic potential.
AB  - Strain BALB/c mice harbor at least two host range variants of marine leukemia
      virus. One variant, which is host-cell tropic, is the predominant isolate from
      neoplastic tissues and produced lymphoreticular neoplasms when injected into
      BALB/c newborn mice. A second variant, whicht is isolated throughout life, grows
      poorly in host embryonic cells in culture and was not associated with
      lymphoreticular neoplasm induction when injected into newborn BALB/c mice.

PMID- 4353360
TI  - Human papovavirus (JC): induction of brain tumors in hamsters.
AB  - Eighty-three percent of hamsters inoculated at birth with JC virus, a human
      papovavirus isolated from brain tissue of a case of progressive multifocal
      leukoencephalopathy, developed malignant gliomas within 6 months. Three brain
      tumors have been serially transplanted as subcutaneous tumors. JC virus was
      isolated from five of seven tumors tested. Cells from four tumors were cultivated
      in vitro. These cells contained an intranuclear antigen with the characteristics
      of a T antigen, and this antigen was antigenically related to SV40 T antigen.
      Although virus was not recovered from extracts of serially cultured tumor cells,
      JC virus was rescued when one tumor cell line was fused with permissive cells.

PMID- 4353361
TI  - Alterations in the ontogeny and specific activity of phosphomonoesterases
      associated with abnormal chondrogenesis and osteogenesis in the limbs of fetuses
      from folic acid-deficient pregnant rats.

PMID- 4353362
TI  - Primary pulmonary cavitating carcinomas.

PMID- 4353363
TI  - [On the occurrence of glioblastomas in the caudal brain stem].

PMID- 4353364
TI  - A rapid separation of the four major deoxynucleosides and deoxyinosine by high
      pressure liquid cation-exchange chromatography.

PMID- 4353365
TI  - Quantitation of radio-ligand binding data using a desk-top calculator in the
      program mode.

PMID- 4353366
TI  - Tissue collagenase: a simplified, semiquantitative enzyme assay.

PMID- 4353367
TI  - A sensitive method for estimating 5-phosphoribosyl 1-pyrophosphate in Escherichia
      coli.

PMID- 4353368
TI  - Micro method for determination of borohydride with NAD+.

PMID- 4353369
TI  - Isolation of rat liver microsomes by gel filtration.

PMID- 4353370
TI  - [Variations in the eosionophil count, glucose, free fatty acids, calcium and
      magnesium contents of sheep blood within the period of one day, and effects of
      various hormones on them (ACTH, prednisolone, adrenaline)].

PMID- 4353371
TI  - [Occurrence of Clostridium perfringens and its toxins and Clostridium perfringens
      enterotoxemia in cattle].

PMID- 4353372
TI  - Characterization of neuromuscular block produced by streptomycin.

PMID- 4353373
TI  - The effect of angiotensin II and other vasoactive drugs on isolated portal vein
      preparations.

PMID- 4353374
TI  - [Activation of ifosfamide in man and animal].

PMID- 4353375
TI  - Effect of propranolol on the isolated phrenic nerve-diaphragm preparation of the
      rat.

PMID- 4353376
TI  - [Kinetics of the bactericidal effect of ampicillin, penicillin G, carbenicillin,
      cephalothin, kanamycin, gentamycin, polymyxin B and sulfamethoxazole-trimethoprim
      on Escherichia coli].

PMID- 4353377
TI  - Alkaline ribonuclease and phosphodiesterase activity in rat liver plasma
      membranes.
AB  - The ribonuclease and phosphodiesterase activities of rat liver plasma membranes,
      purified from the crude nuclear fraction by centrifugation in an A-XII zonal
      rotor and flotation, were examined and compared. The plasma membrane is
      responsible for between 65 and 90% of the phosphodiesterase activity of the cell
      and between 25 and 30% of the particulate ribonuclease activity measured at pH8.7
      in the presence of 7.5mm-MgCl(2). Both enzymes were most active between pH8.5 and
      8.9. Close to the pH optimum, both enzymes were more active in Tris buffer than
      in Bicine or glycine buffer. Both plasma-membrane phosphodiesterase and
      ribonuclease were strongly activated by Mg(2+), there being at least a 12-fold
      difference between the activity in the presence of Mg(2+) and of EDTA. There is,
      however, a difference in the response of the enzymes to Mg(2+) and EDTA in that
      the phosphodiesterase is fully activated by 1.0mm-MgCl(2) and fully inhibited by
      1.0mm-EDTA, whereas the ribonuclease requires 7.5mm-MgCl(2) for full activation
      and 5mm-EDTA for full inhibition. Density-gradient centrifugation has indicated
      that on solubilization in Triton X-100 most of the ribonuclease activity is
      released into a small fragment of the same size as that containing the
      phosphodiesterase activity. The relationship between the two activities is
      discussed in view of these results.

PMID- 4353378
TI  - Turnover of protein-bound serine phosphate in respiring slices of guinea-pig
      cerebral cortex. Effects of putative transmitters, tetrodotoxin and other agents.
AB  - 1. The effect of various agents on the turnover of protein-bound phosphorus in
      respiring slices of cerebral cortex was studied. 2. Confirming previous work
      turnover was increased by the application of electrical pulses for 10s to the
      tissue. 3. Turnover was also increased by exposure of the slices for 10min to
      noradrenaline (0.5mm), 5-hydroxytryptamine (1mum) and histamine (0.1mm). 4. When
      slices were stimulated by electrical pulses in the presence of histamine the
      increase in turnover was the sum of the responses given by each agent above,
      suggesting that different phosphorylating systems were involved. 5. Tetrodotoxin
      (0.5mum) blocked the increased turnover due to electrical pulses, but not that
      due to histamine. Tetrodotoxin also prevented the increase in tissue cyclic AMP
      content caused by the application of electrical pulses. 6. Phosphoprotein
      turnover was not affected by adenosine, despite the increase in tissue cyclic AMP
      content given by this agent. 7. Adenosine blocked the phosphoprotein response to
      histamine, but did not affect the response to electrical pulses. 8. The results
      are discussed in relation to the hypothesis that the stimulation of protein
      phosphorus turnover by electrical pulses is secondary to the release of cyclic
      AMP in the tissue.

PMID- 4353379
TI  - Protein kinase activity in membrane preparations from ox brain. Stimulation of
      intrinsic activity by adenosine 3':5'-cyclic monophosphate.
AB  - 1. Properties of the stimulation by cyclic AMP of the intrinsic protein kinase
      activity of membrane fragments from ox brain were studied. 2. Stimulation of
      activity declined from about 100% at 1min to less than 20% at 10min. The time
      course was explained by the observation that cyclic AMP did not stimulate
      turnover of protein-bound serine phosphate once the membrane protein was fully
      phosphorylated. 3. Cyclic AMP accelerated the activity of a component of the
      basal activity rather than activating a different kinase. 4. The pH optimum for
      both the stimulated and basal activities was 7.2-7.4. NaCl (100mm) and KCl (10
      100mm) inhibited the stimulated activity but did not affect the basal activity.
      5. Strychnine and theophylline inhibited both activites equally, but the
      stimulated activity was more sensitive to inhibition by adenosine, bicuculline,
      vinblastin, veratrine, N-ethylmaleimide and cysteine. 6. No firm evidence for a
      role for endogenous cyclic AMP in the basal activity was found, but the
      possibility was not excluded. 7. Some 90% of both the stimulated and basal
      activities remained in an insoluble form after treatment of the membrane
      fragments with Triton X-100 (0.5%).

PMID- 4353380
TI  - The heterogeneous distribution of acid hydrolases within a homogeneous population
      of cultured mammalian cells.
AB  - 1. Chinese-hamster ovary fibroblasts were cultured to provide a homogeneous cell
      population. Homogenates obtained from these cells were fractionated by
      centrifugation techniques and the resulting fractions were analysed for protein
      and for enzymes representative of certain subcellular particles. 2. Unlike those
      in rat liver homogenates, the mitochondrial and lysosomal populations proved
      impossible to separate by differential centrifugation owing to the similarity of
      their sedimentation properties. Their resolution was possible by using isopycnic
      centrifugation in a continuous sucrose density gradient. 3. The mitochondrial
      population equilibrated at a density of 1.17g.cm(-3) as in rat liver homogenates.
      However, the lysosomal population equilibrated at a lower rather than a higher
      density position than the mitochondria and the probable reasons for this are
      discussed. 4. The lysosomal population subdivided into two groups characterized
      by differences in acid hydrolase content and equilibrium densities. The fraction
      with a density of 1.15g.cm(-3) contained the majority of arylsulphatases A and B,
      of cathepsin and of beta-acetylglucosaminidase activities, whereas that with a
      density of 1.09g.cm(-3) contained the majority of the acid phosphatase and acid
      ribonuclease activities. The probable division of the lysosomal population of a
      single cell into a number of distinguishable subgroups is suggested.

PMID- 4353381
TI  - The effects of calcium ions on the activities of trehalase, hexokinase,
      phosphofructokinase, fructose diphosphatase and pyruvate kinase from various
      muscles.
AB  - 1. The effects of Ca(2+) on the activities and regulatory properties of
      trehalase, hexokinase, phosphofructokinase, fructose diphosphatase and pyruvate
      kinase from vertebrate red and white muscle and insect fibrillar and non
      fibrillar muscle have been investigated. These muscles were selected because of
      the possible difference in the role of glycolysis in energy production in the
      vertebrate muscles, and the possible difference in the role of Ca(2+) in the
      control of contraction in the two types of insect muscle. An increase in Ca(2+)
      concentration from 0.001mum to 10mum did not modify the activities nor did it
      modify the regulatory properties of these enzymes from these various muscles. 2.
      Concentrations of Ca(2+) above 0.1mm inhibited the activities of hexokinase and
      phosphofructokinase from the different muscles. It has been suggested that this
      inhibition may provide the basis for a theory of regulation of glycolysis
      (Margreth et al., 1967). If phosphofructokinase is located within the
      sarcoplasmic reticulum, its activity will be inhibited when the muscle is at
      rest, but the release of Ca(2+) from the reticulum during contraction will lead
      to a stimulation of its activity and hence an increase in glycolytic flux. The
      distribution of hexokinase and phosphofructokinase in the various cell fractions
      of these muscles was very variable. In particular, both enzymes were present
      almost exclusively in the 100000g supernatant fraction in the extracts of insect
      flight muscles. Thus there is no correlation between the properties of the
      enzymes and their distribution in muscle. 3. It is concluded that Ca(2+) does not
      control the activities of the important regulatory enzymes of glycolysis in
      muscle. It is suggested that in some muscles the sensitivity of the control
      mechanism at the level of phosphofructokinase to changes in the concentration of
      AMP may be increased by a process known as ;substrate-cycling'.

PMID- 4353383
TI  - Changes in enzyme activities and distributions during glucose de-repression and
      respiratory adaptation of anaerobically grown Saccharomyces carlsbergensis.
AB  - 1. During anaerobic glucose de-repression the respiration rate of whole cells of
      Saccharomyces carlsbergensis remained constant and was insensitive to antimycin A
      but was inhibited by 30% by KCN. Aeration of cells for 1 h led to increased
      respiration rate which was inhibited by 80% by antimycin A or KCN. 2. Homogenates
      were prepared from sphaeroplasts of anaerobically grown, glucose de-repressed
      cells and the distribution of marker enzymes was investigated after zonal
      centrifugation on sucrose gradients containing MgCl(2). These homogenates
      contained no detectable cytochrome c oxidase or catalase activity. The complex
      density distributions of NADH- and NADPH-cytochrome c oxidoreductases and
      adenosine triphosphatase(s) [ATPase(s)] were very different from those of
      anaerobically grown, glucose-repressed cells. 3. The specific activity of total
      ATPase was lowered and sensitivity to oligomycin decreased from 58 to 7% during
      de-repression. 4. Cytochrome c oxidase and catalase activities were detectable in
      homogenates of cells after 10min aeration. Zonal centrifugation indicated
      complex, broad sedimentable distributions of all enzyme activities assayed; the
      peaks of activity were at 1.27g/ml. 5. Centrifugation of homogenates of cells
      adapted for 30min and 3 h indicated a shift of density of the major sedimentable
      peak from 1.25g/ml (30min) to 1.235g/ml (3 h). After 30min adaptation a minor
      zone of oligomycin-sensitive ATPase and 15% of the total cytochrome c oxidase
      activities were detected at rho=1.12g/l; these particles together with those of
      higher density containing cytochrome c oxidase, ATPase and NADH-cytochrome c
      oxidoreductase activities were all sedimented at 10(5)g-min. 6. Electron
      microscopy indicated that the mitochondria-like structures of anaerobically
      grown, glucose-de-repressed cells were similar to those of repressed cells. After
      10min of respiratory adaptation highly organized mitochondria were evident which
      resembled the condensed forms of mitochondria of aerobically grown, glucose-de
      repressed cells. High-density zonal fractions of homogenates of cells after
      adaptation also contained numerous electron-dense vesicles 0.05-0.2mum in
      diameter. 7. The possibility that the ;promitochondria' of anaerobically grown
      cells may not be the direct structural precursors of fully functional
      mitochondria is discussed.

PMID- 4353382
TI  - Developmental changes in microheterogeneity of foetal plasma glycoproteins of
      mice.
AB  - Changes in microheterogeneity of foetal plasma glycoproteins during development
      of mouse embryos were investigated. Analysis of foetal plasma by polyacrylamide
      gel electrophoresis indicated three major zones of proteins: (1) transferrins,
      (2) alpha-foetoproteins and (3) albumin. Three transferrins (Tr1, Tr2, Tr3) and
      five alpha-foetoproteins (Fp1, Fp2, Fp3, Fp4, Fp5) were resolved. Evidence for
      the presence of transferrins was the binding of (59)Fe to the three
      electrophoretic variants. By day 15.5 of gestation, there was a marked increase
      in the more-acidic components (Tr3, Fp4, Fp5) and a decrease in the less-acidic
      ones (Tr1, Tr2, Fp1, Fp2, Fp3). Treatment of foetal plasma with neuraminidase at
      this time of development converted the more acidic components into Tr1 and Tr2
      and Fp1, Fp2 and Fp3. Furthermore, it was shown that early in development (day
      12.5) only the less-acidic components of transferrin and alpha-foetoprotein were
      synthesized; at the later time in development (day 14.5) new synthesis of the
      acidic components of both groups occurred. That these more-acidic components of
      alpha-foetoprotein (Fp4, Fp5) were in fact electrophoretic variants of the less
      acidic alpha-foetoproteins was shown by the immunoprecipitation of labelled Fp4
      and Fp5 with anti-Fp1, anti-Fp2 and anti-Fp3. From these results it is postulated
      that the plasma glycoproteins that are synthesized later in development contain
      increased amounts of sialic acid and that the observed changes in
      microheterogeneity of these proteins represent regulation of glycoprotein
      biosynthesis at the level of carbohydrate attachment.

PMID- 4353384
TI  - Phosphorylation of high-molecular-weight membrane protein species in Chinese
      hamster ovary cells in culture: effect of 6-N,2'-O-dibutyryladenosine 3':5'
      cyclic monophosphate plus testosterone.
AB  - Growth of Chinese-hamster ovary cells in [(32)P]phosphate and [(3)H]leucine and
      subsequent assay of the plasma membranes reveals phosphorylation in two protein
      regions corresponding to molecular weights of 280000 and 195000. Culture in the
      presence of the 6-N,2-O'-dibutyryl derivative of cyclic AMP plus testosterone
      does not stimulate [(32)P]-phosphate incorporation, but determines a modification
      in the qualitative pattern of phosphorylation.

PMID- 4353385
TI  - Pencillin amidase production by Bacillus megaterium.

PMID- 4353386
TI  - Phospholipase-C from Bacillus cereus: production, purification, and properties.

PMID- 4353387
TI  - Detection of circulating hepatoma D23 antigen and immune complexes in tumour
      bearer serum.
AB  - Serum from rats bearing progressively growing aminoazo dye-induced rat hepatomata
      has been fractionated by Sephadex G150 gel filtration chromatography and isolated
      fractions have been examined by indirect membrane immunofluorescence techniques
      to detect tumour specific antigen and antibody. Hepatoma D23-specific antigenic
      activity was associated with material (of approximate molecular weight <150,000)
      isolated in the included volume of the gel at pH 7.3. The fraction excluded from
      the gel (of approximate molecular weight >150,000) was adjusted to pH 3.0 and
      further separated by Sephadex G150 gel filtration chromatography at pH 3.0 into
      gel included and excluded fractions. Hepatoma D23 specific antibody, demonstrable
      by membrane immunofluorescence staining of hepatoma D23 cells, was found to be
      eluted in the excluded volume and specific antigenic activity was retarded into
      the included volume of the gel. These results indicate that hepatoma D23 bearer
      serum contains free circulating tumour specific antigen in excess, together with
      specific immune complexes. The presence of these factors in tumour bearer serum
      is discussed in terms of "blocking" phenomena whereby serum factors may protect
      tumour cells from sensitized lymphocyte cytotoxic attack.

PMID- 4353388
TI  - A new model for inducing malignant ovarian tumours in rats.
AB  - After the implantation of ovarian tissue into the spleen of gonadectomized female
      Sprague-Dawley rats (splenic ovary), luteomata and later benign granulosa or
      granulosa-theca cell tumours develop. Treatment of these rats with 7,12
      dimethylbenz(a)anthracene (DMBA), given intravenously, 2 mg/kg body weight
      weekly, total dosage 40 mg/kg, immediately and especially 25 weeks after
      implantation of ovarian tissue into the spleen, led to malignant, partially
      metastasizing granulosa, and in one case theca cell tumours, 16-46 weeks after
      beginning the carcinogen treatment. No malignant neoplastic growth was seen when
      diethylnitrosamine (DEN), 20 mg/kg once weekly for life, was injected
      subcutaneously immediately or 25 weeks after implanting ovarian tissue.Since the
      normal, non-implanted rat ovary was not affected by DMBA treatment the malignant
      transformation of splenic ovaries in the respective experimental groups may be
      related to the increased stimulation by pituitary gonadotrophins and formation of
      luteomata or beginning granulosa and theca cell proliferations.

PMID- 4353390
TI  - Mammary tumour and hepatoma suppression by dietary restriction in C3H Avy mice.

PMID- 4353389
TI  - Enzyme activated alkylating agents.

PMID- 4353391
TI  - Possible viral aetiology of human breast cancer.

PMID- 4353392
TI  - A comparison of dream content in laboratory dream reports of schizophrenic and
      depressive patient groups.

PMID- 4353393
TI  - Cyclic AMP and adenyl cyclase in the developing rat brain.

PMID- 4353394
TI  - [For patient and parents inapparent recurrence of urinary tract infection in the
      child. 1. Definition and occurrence of the inapparent recurrence following acute
      urinary tract infections].

PMID- 4353395
TI  - [Ethionine-effect on the rat exocrine pancreas in different nutritional
      conditions].

PMID- 4353396
TI  - Two types of response patterns from cat retinal ganglion cells to moving stimuli.

PMID- 4353397
TI  - Cyclic 3',5'-adenosine monophosphate in Tetrahymena pyriformis.

PMID- 4353398
TI  - The effect of semicarbazide pretreatment on the depressant action of
      barbiturates.

PMID- 4353399
TI  - Toxicity of polychlorinated biphenyls increased with simultaneous ingestion of
      alkylbenzene sulfonic acid salt.

PMID- 4353400
TI  - In vitro corticosteroidogenesis by the adrenal gland of the chicken (Gallus
      domesticus).

PMID- 4353401
TI  - [Vestibular recruitment and its demonstration using new neuro-otological graphic
      methods].

PMID- 4353402
TI  - Experimental studies of peribronchography.

PMID- 4353403
TI  - Determining the biological age of the preschool child from a hand-wrist
      radiograph.

PMID- 4353405
TI  - Five classes of visual interneurons in the optic nerve of the hermit crab.

PMID- 4353404
TI  - A psychophysiological study of nightmares and night terrors. I. Physiological
      aspects of the stage 4 night terror.

PMID- 4353406
TI  - Restorative effects of cyclic AMP on complex bioelectric activities of cultured
      fetal rodent CNS tissues after acute CA++ deprivation.

PMID- 4353407
TI  - Chemosensitivity of mouse neuroblastoma cells in vitro.

PMID- 4353408
TI  - Melanotic medulloblastoma of the cerebellum.

PMID- 4353410
TI  - How is the H-reflex modulated during rapid eye movement (REM) sleep?

PMID- 4353412
TI  - Superinfection of simian virus 40 transformed human cells with human adenovirus.

PMID- 4353411
TI  - Studies on bovine para-influenza (type-3) virus.

PMID- 4353409
TI  - Determination of the frequency response of isometric soleus muscle in the cat
      using random nerve stimulation.
AB  - 1. The frequency response of isometric soleus muscle was determined efficiently
      by analysis of the unfused tension generated during short periods of random
      stimulation of the divided ventral roots, in anaesthetized cats.2. Despite the
      complexities of skeletal muscle, the frequency response of soleus, at moderate
      lengths and stimulation rates in the physiological range, is closely approximated
      by the frequency response function for a simple, linear, second-order system near
      critical damping.3. The soleus muscle shows a uniformly high sensitivity to
      fluctuations in nerve activity over a range of frequencies similar to the range
      of frequencies of muscular activity observable during behaviour. The nerve-muscle
      preparation appears to be well suited for smooth and steady motor activity, since
      it is much less responsive to the higher frequency components contained in
      individual action potentials or generated in tremor.4. The second-order
      parameters: low-frequency gain, natural frequency and damping ratio provide
      useful descriptions of the changes in the muscle's response caused by variations
      of muscle length, nerve stimulation rate or number of active motor units.5. A
      reduction in tension incurred, for example, during fatigue can be compensated to
      some extent either by a lengthening of the loaded muscle or through an increase
      in neural spike repetition rate. However, both mechanisms produce concomitant
      increases in the ;sluggishness' (increased damping and lower natural frequency)
      of the preparation. This sluggishness may arise out of limitations imposed by the
      mechanism for the re-uptake of calcium into the sarcotubular system.6. One
      naturally occurring method of increasing tension, by recruitment of more active
      motoneurones, seems to be desirable because tension can be augmented in this way
      without an increase in sluggishness. This is presumably because recruitment
      increases the muscle's response without affecting excitation-contraction coupling
      in fibres already active.

PMID- 4353413
TI  - Characteristic behaviour of the cocultures of the SV40 transformed rabbit kidney
      cells and African green monkey kidney cells.

PMID- 4353415
TI  - Glomerulonephritis associated with immune complex deposits and viral particles in
      spontaneous murine leukemia. An electron microscopic study with
      immunofluorescence.

PMID- 4353414
TI  - [Pathologic anatomy of cytomegaly].

PMID- 4353416
TI  - Ultrastructure of parathyroid glands and plasma immunoreactive parathyroid
      hormone in pregnant cows fed normal and high calcium diets.

PMID- 4353417
TI  - Sulfaguanidine protection of mouse liver from carbon tetrachloride-induced
      necrosis.

PMID- 4353419
TI  - Ultrastructural study of cytochrome oxidase in oncocytoma.

PMID- 4353418
TI  - The effect of vincristine on the calcium transport and phospholipid composition
      of rat skeletal muscle microsomes.

PMID- 4353420
TI  - Polypeptide specific for cells with adenovirus 2-SV40 hybrid Ad2+ND1.

PMID- 4353422
TI  - Identification of two distinct species of procollagen synthesized by a clonal
      line of calf dermatosparactic cells.

PMID- 4353421
TI  - Altered metabolism and endogenous cyclic AMP in cultured cells deficient in
      cyclic AMP-binding proteins.

PMID- 4353423
TI  - Localization of rat liver alpha-foetoprotein by cell affinity labelling with
      tritiated oestrogens.

PMID- 4353424
TI  - Serological evidence for CELO virus infection in chickens and turkeys in Denmark.

PMID- 4353425
TI  - Tumor lipids.

PMID- 4353427
TI  - Cyclic 3',5'-adenosine monophosphate in the rat gastric mucosa after starvation,
      feeding, and pentagastrin.

PMID- 4353426
TI  - [Electroencephalographic study of enuresis].

PMID- 4353428
TI  - MHPG excretion in depressive disorders: relation to clinical subtypes and
      desynchronized sleep.
AB  - The urinary excretion of 3-methoxy-4-hydroxyphenylglycol (MHPG) was significantly
      lower in patients with manic-depressive depressions than in patients with chronic
      characterological depressions. There was an inverse relationship between MHPG
      excretion and the amount of time spent in desynchronized sleep, particularly in
      the manic-depressive disorders. Excretion of MHPG was not related to the degree
      of retardation, agitation, or anxiety in these patients.

PMID- 4353429
TI  - Intracellular receptors for 5alpha-dihydrostestosterone in the epididymis of
      adult rats. Comparison with the androgenic receptors in the ventral prostate and
      the androgen binding protein (ABP) in the testicular and epididymal fluid.

PMID- 4353430
TI  - The metabolism of estriol in rabbits.

PMID- 4353431
TI  - Retro-steroids. I. Metabolism of the progestogen 6-chloro-9 , 10 -pregna-1,4,6
      triene-3,20-dione in man.

PMID- 4353433
TI  - Primary brain tumors: tumor immunity and immunocompetence.

PMID- 4353434
TI  - Granular cell myoblastomas of the pituitary region.

PMID- 4353432
TI  - Progesterone binding in the immature mouse and rat uterus.

PMID- 4353435
TI  - Study of Japanese encephalitis virus in Chiangmai Valley, Thailand. I.
      Introduction and study design.

PMID- 4353437
TI  - Study of Japanese encephalitis virus in Chiangmai Valley, Thailand. 3. Human
      seroepidemiology and inapparent infections.

PMID- 4353436
TI  - Study of Japanese encephalitis virus in Chiangmai valley, Thailand. II. Human
      clinical infections.

PMID- 4353438
TI  - Epidemiology of sudden infant death syndrome and lower respiratory tract disease
      in young children: a comparison.

PMID- 4353439
TI  - Epidemiology of respiratory syncytial virus infection among infants and children
      in Chicago.

PMID- 4353440
TI  - The therapeutic tumult and the ophthalmologist. 35th De Schweinitz lecture.

PMID- 4353441
TI  - The effect of ophthalmic ointments on corneal wound healing.

PMID- 4353442
TI  - Cyclomegalovirus retinitis.

PMID- 4353443
TI  - Studies of nuclei separated by zonal centrifugation from liver of rats treated
      with thioacetamide.
AB  - 1. The effects of the inclusion of thioacetamide in the diet on the properties of
      rat liver nuclei were studied both in adolescent rats, in which the parenchymal
      cells contain diploid nuclei, and in young adult rats, with a high proportion of
      tetraploid nuclei. 2. These investigations included a survey of the sedimentation
      properties of the nuclei, the nuclear volumes, content of DNA, RNA and protein,
      the incorporation in vivo of [(3)H]thymidine into DNA and [(14)C]orotate into
      RNA, and measurements of the activity of RNA polymerase and ribonuclease. These
      studies were conducted on nuclei fractionated by zonal centrifugation. 3. In both
      groups of animals, exposure to thioacetamide produced large numbers of nuclei
      that were abnormal in their chemical composition and enzymic activity. The
      changes were complex as regards both the types of nuclei that were affected and
      in their variation with time. 4. In adolescent rats two waves of synthesis of DNA
      and RNA were observed, one at 3 days and the other after 2 weeks of treatment.
      The first decline in the incorporations into both DNA and RNA coincided with a
      decrease in the pool sizes of some of the precursors. The activity of RNA
      polymerase was not substantially altered. A marked increase in the content of
      protein was observed before the first wave of synthesis. The normal progressive
      increase in tetraploid nuclei was prevented. 5. In young adult rats two waves of
      DNA synthesis were detected. Each was preceded by a large increase in the amount
      of protein per nucleus but was not accompanied by increased RNA synthesis. After
      4 weeks of treatment, the diploid stromal nuclei appeared mainly unaffected and
      large numbers of tetraploid nuclei with a greatly increased quantity of protein
      were observed.

PMID- 4353445
TI  - Adrenal microsomal C19-steroid 5alpha-reductase activity in the Snell
      transplantable rat adrenocortical tumour 494 and the effect of oestradiol,
      testosterone propionate and adrenocorticotrophin in intact and gonadectomized
      rats.
AB  - The C(19)-steroid 5alpha-reductase activity in the microsomal fraction of rat
      adrenal tissue under various hormonal treatments was examined. In intact control
      rats the activity is similar in both males and females, and after gonadectomy it
      is markedly increased. Treatment with oestradiol (150mug/day per animal for 7
      days) or testosterone propionate (2mg/day per animal for 7 days) lowered the
      activity of 5alpha-reductase in castrated animals to approximately the values for
      intact animals in both sexes, and in intact animals the activity was also
      decreased by these treatments. The enzyme activity was also decreased by
      adrenocorticotrophin treatment but to a lesser extent than by the steroid
      hormones. The activity of the 5alpha-reductase enzyme in the Snell adrenocortical
      tumour 494 is very low when incubated as a whole homogenate, but the activity in
      microsomal material of the tumour was measured and unexpectedly found to be
      similar to that in intact controls.

PMID- 4353444
TI  - Isolation and characterization of a rough microsomal fraction from rat kidney
      that is enriched in lysosomal enzymes.
AB  - 1. A special population of rough microsomal material (microsomes) rich in
      lysosomal acid hydrolases was separated by isopycnic centrifugation as a discrete
      fraction (RM(2)) from the bulk of rough microsomal material in rat kidney because
      of its greater density. 2. The specific activities of five acid hydrolases in the
      RM(2) fraction were approximately one-half those of a purified lysosomal (L)
      fraction and 10- to 30-fold greater than those of an ordinary rough microsomal
      (RM(1)) fraction. 3. These special rough microsomes have a distinctive
      ultrastructure and electron-cytochemical properties. Their cisternal content
      resembles the matrix of lysosomes in that it is electron-dense, osmiophilic and
      plumbophilic and gives a positive reaction for acid phosphatase activity. 4.
      Polyacrylamide-gel electrophoresis of soluble proteins from the L fraction
      resolved nine anionic glycoproteins, most of which exhibit acid hydrolase
      activities (Goldstone & Koenig, 1970, 1973; Goldstone et al., 1971a). The most
      anionic glycoprotein is the acidic lipoglycoprotein of the lysosomal matrix
      (Goldstone et al., 1970). 5. Polyacrylamide-gel electrophoresis of soluble
      proteins from the RM(2) fraction resolved two cationic glycoproteins with acid
      hydrolase activities (Goldstone & Koenig, 1973) and an anionic glycoprotein with
      the same electrophoretic mobility as the lysosomal lipoglycoprotein, but without
      its lipid constituents or capacity to bind the basic fluorochrome Acridine
      Orange. These constituents are considered to be the precursors of the lysosomal
      glycoproteins.

PMID- 4353446
TI  - Control of ovarian cholesterol ester biosynthesis.
AB  - 1. Experimental evidence is presented for a role of progesterone and 20alpha
      hydroxypregn-4-en-3-one as inhibitors of cholesterol ester synthetase in the
      acute depletion of ovarian cholesterol ester after trophic stimulation. 2.
      Luteinizing hormone in vitro decreased by 84% the rate of esterification of
      cholesterol with added [(14)C]oleate by slices of rabbit ovarian interstitial
      tissue; this effect was mimicked by cyclic AMP (adenosine 3':5'-cyclic
      monophosphate) in vitro, and occurred without large changes in precursor pool
      sizes or membrane permeability. 3. Cyclic AMP was shown to have no direct effect
      on cholesterol ester synthetase or cholesterol esterase in cell-free extracts of
      rabbit ovarian interstitial tissue, but decreased the activity of cholesterol
      ester synthetase (not that of cholesterol esterase) in extracts prepared from
      slices previously incubated with it. 4. The inhibitory effect of cyclic AMP on
      esterification of cholesterol with added [(14)C]-oleate was prevented by both
      cycloheximide and aminoglutethimide phosphate (which also inhibited steroid
      synthesis in response to cyclic AMP). 5. Cyclic AMP raised the intracellular
      concentrations of progesterone and 20alpha-hydroxypregn-4-en-3-one in incubated
      slices by factors of 2.8 and 3.9 respectively. 6. Cycloheximide and
      aminoglutethimide phosphate administered in vivo blocked cholesterol ester
      depletion in response to luteinizing hormone in rats; in these ovaries
      cycloheximide and aminoglutethimide phosphate decreased the concentrations of
      progesterone and 20alpha-hydroxypregn-4-en-3-one and luteinizing hormone raised
      them. 7. Progesterone and 20alpha-hydroxypregn-4-en-3-one added to cell-free
      extracts of rabbit ovarian interstitial tissue in vitro (at concentrations
      comparable with those found in incubated slices) inhibited cholesterol ester
      synthetase by up to 85%. 8. The results are discussed with reference to the acute
      control of cholesterol ester concentrations in the ovary and adrenal cortex.

PMID- 4353448
TI  - [Modification of the length of gestation in swine after the administration of
      ACTH to the fetus].

PMID- 4353447
TI  - Hepatic lipid droplets. Isolation, morphology and composition.
AB  - The floating lipid layer isolated centrifugation of rat liver was examined for
      composition and ultrastructure. It was chiefly composed of triglycerides and
      cholesterol esters plus much smaller amounts of free cholesterol, diglycerides,
      phospholipid and protein. No free fatty acids were detected. The triglyceride and
      cholesterol ester fractions consisted mostly of esters of linoleic acid, oleic
      acid and palmitic acid. Electron micrographs of the floating lipid layer revealed
      numerous spherical osmiophilic droplets having a mean diameter of 0.5-2mum with a
      very-thin dense outer coat. Similar structures were observed as organelles in
      electron micrographs of the intact liver cell. The amount of triglyceride in the
      layer decreased in rats starved for 72h, but pellet triglyceride (homogenate
      minus the floating lipid layer) was unchanged. These results suggest that the
      floating lipid layer is the representative in vitro of lipid-rich organelles
      which probably function as a depot form of hepatic-cell neutral lipid.

PMID- 4353449
TI  - [Demonstration of an electronic alteration in carcinogenesis].

PMID- 4353450
TI  - The effects of selective interruption and deprivation of sleep in the human
      newborn.

PMID- 4353451
TI  - Hypothyroidism and the maturation of the hypothalamo-hypophyseal-adrenal axis.

PMID- 4353452
TI  - The effect of phentolamine on adenylate cyclase and on isoproterenol stimulation
      in leukocytes from asthmatic and nonasthmatic subjects.

PMID- 4353453
TI  - An epizootic of malignant catarrhal fever in feedlot cattle.

PMID- 4353454
TI  - Evidence of bovine C-type (leukemia) virus in dairy cattle.

PMID- 4353455
TI  - Incidence of Clostridium perfringens in dehydrated soup, gravy, and spaghetti
      mixes.

PMID- 4353456
TI  - [Objectives and diagnostic significance of eye-tracking test and skipping eye
      tracking test].

PMID- 4353457
TI  - Renal hamartomas and nephroblastomatosis with fetal gigantism: a familial
      syndrome.

PMID- 4353458
TI  - Varicella reactivation in nephrotic syndrome treated with cyclophosphamide and
      adrenal corticosteroids.

PMID- 4353460
TI  - [The combined effects of N-butylscopolamine bromide and sulpyrin. I.
      Antispasmodic activity, analgesic activity and acute toxicity].

PMID- 4353459
TI  - Complete analysis of levodopa capsules and tablets by GLC.

PMID- 4353461
TI  - Peripheral neuropathy secondary to isoniazid-induced pyridoxine deficiency.

PMID- 4353462
TI  - [Various aspects of electromyography in current practice].

PMID- 4353463
TI  - Some clinical aspects of non traumatic mechanical lesions of peripheral nerves.
      Analysis of 3465 personal cases.

PMID- 4353464
TI  - Carbohydrate metabolism in the rat uterus during early pregnancy.

PMID- 4353465
TI  - Attempts to propagate human tumor explants in mice inoculated with human thymus
      antiserum.

PMID- 4353466
TI  - An examination of two bovine respiratory disease vaccines.

PMID- 4353467
TI  - Modification of metabolic effects of ethanol by fructose.

PMID- 4353468
TI  - Metabolism of fructose in liver.

PMID- 4353469
TI  - Spectroscopic methods in biology, with application to neurophysiology.

PMID- 4353470
TI  - [Effects of nutrition and infections on bone development of children in a rural
      area of Guatemala].

PMID- 4353471
TI  - Compressive behaviour of a physiological tissue.

PMID- 4353472
TI  - [Neutralization of the infective power of the foot-and-mouth disease virus in
      cell culture by using serums from pigs immunized with a purified viral protein].

PMID- 4353473
TI  - [Gamma-ray inactivation of Escherichia coli MRE 600 ribosomes; demonstration of
      an inhibition factor of their GTPase activity].

PMID- 4353474
TI  - The effects of protein on lipid organization in a model membrane system: a spin
      probe and x-ray study.

PMID- 4353476
TI  - 3-(Tetraacetyl glucopyranos-2-yl)-1-(2-chloroethyl)-1-nitrosourea, an antitumor
      agent with modified bone marrow toxicity.

PMID- 4353477
TI  - Enzymatic and immunological studies on pyruvate carboxylase in livers and liver
      tumors.

PMID- 4353478
TI  - Studies on certain cytoplasmic enzymes and specific estrogen receptors in human
      breast cancer and in nonmalignant diseases of the breast.

PMID- 4353475
TI  - Filamentous forms of enveloped A particles in cell cultures from chemically
      induced rat hepatomas.

PMID- 4353479
TI  - The isolation and characterization of gallium-binding granules from soft tissue
      tumors.

PMID- 4353480
TI  - Inhibition by N6, O2'-dibutyryl 3',5'-cyclic adenosine monophosphate of phosphate
      transport and metabolism in BHK21C13 and BHK21Py cells.

PMID- 4353481
TI  - Folate deficiency in rats bearing the Walker tumor 256 and the Novikoff hepatoma.

PMID- 4353483
TI  - Patterns of damage and repair of liver DNA induced by carcinogenic methylating
      agents in vivo.

PMID- 4353482
TI  - A method for measuring DNA damage and repair in the liver in vivo.

PMID- 4353484
TI  - A comparative study of the interaction between concanavalin A and mitochondria
      from normal and malignant cells.

PMID- 4353485
TI  - Effect of hydrocortisone on cell viability, Epstein-Barr virus genome expression,
      and interferon synthesis in human lymphoblastoid cell lines.

PMID- 4353486
TI  - The estimation of citrate in serum and urine using a citrate lyase technique.

PMID- 4353487
TI  - Radioimmunoassay of oestriol in pregnancy plasma.

PMID- 4353488
TI  - The response to plant mitogens of two subpopulations of lymphocytes in a case of
      chronic lymphocytic leukaemia.

PMID- 4353489
TI  - Virus-specific immunoglobulins in multiple sclerosis.

PMID- 4353491
TI  - Coordination: the key to rehabilitation.

PMID- 4353492
TI  - Returning long-term patients to the community.

PMID- 4353490
TI  - Reversible blockage of specific synaptic transmission by localized and moderate
      cooling with a vacuum insulated probe connected to a closed circuit apparatus.

PMID- 4353493
TI  - A network of volunteers for community programs.

PMID- 4353494
TI  - A support group for maintaining chronic patients outside the hospital.

PMID- 4353495
TI  - Separation of cocaine, some of its metabolites and congeners on glass fibre
      sheets.

PMID- 4353496
TI  - Agricultural fungicides. I. Identification of systemic fungicides using thin
      layer chromatography.

PMID- 4353497
TI  - Rapid determination of some plasma oxypurines using high-pressure liquid
      chromatography.

PMID- 4353498
TI  - The effect of proteolytic enzymes on the induction of heterotopic bone formation
      by demineralized dentin in guinea pigs.

PMID- 4353499
TI  - Characterization of two simian virus 40-specific RNA molecules from infected BS-C
      1 cells.
AB  - Two discrete simian virus 40 (SV40) RNA species sedimenting at 19 and 16S,
      respectively, that are present in infected BS-C-1 cells were characterized with
      respect to the base composition and the ribonuclease T1 fingerprints. The base
      composition of the 19S SV40 RNA was found to be cytidylic acid (C), 23.0;
      adenylic acid (A), 28.3; guanylic acid (G), 23.9; and uridylic acid (U), 24.8;
      that of the 16S SV40 RNA was C, 19.3; A, 34.0; G, 22.0; and U, 24.7 mol%.
      Analysis of the ribonuclease T1 fingerprints indicated a difference in the base
      sequence of the 19 and 16S SV40 RNA. The presence of long sequences of adenylic
      acid residues (poly A) in these viral RNAs was confirmed.

PMID- 4353500
TI  - Influence of gene 55 on the regulation of synthesis of some early enzymes in
      bacteriophage T4-infected escherichia coli.
AB  - In Escherichia coli B infected with phage T4 with mutations in gene 55 the shut
      off of synthesis of two early enzymes was found to be delayed 10 to 15 min as
      compared to wild-type T4 infection. The kinetics of early enzyme formation was
      very similar to that obtained after DNA-negative mutant infection. The
      transcription of gene 1 (one of the genes coded for early enzymes) ceased at 9 to
      12 min after infection whether the gene 55 product was active or not, as
      determined by the time dependence of fluorouracil rescuability of DNA synthesis
      in cells infected with a gene 1 amber mutant. The synthesis of the major part of
      the early RNA species, determined by pulse-labeling with uracil-5-(3)H, was
      furthermore found to be regulated independently of gene 55. An explanation for
      the extended early enzyme synthesis in DNA-negative and gene 55 mutant infection
      is offered: translation of early messengers is restricted after about 12 min in
      wild-type infection, whereas in cells infected with DNA-negative or gene 55
      mutants, i.e., the absence of late protein synthesis, early messengers direct the
      formation of early enzymes for a longer time.

PMID- 4353501
TI  - Adaptation of plaque assay methods to the in vitro quantitation of the radiation
      leukemia virus.
AB  - A modification of the XC cell procedure for murine leukemia virus assay which
      yields quantitative data over a wide range of virus concentrations is described.
      By using serial passage of infected cell cultures and reversal of the plating
      sequence in the XC procedure, titers of radiation leukemia virus (RadLV) were
      obtained which were about 10-fold higher than those found by using the
      conventional assay. By using the modified procedure, it was observed that, even
      at high multiplicities of infection, less than 10% of the cells function as
      infective centers, although the proportion increases with serial passage. It was
      also observed that exposure of infected cells to UV light, which is commonly used
      to make plaques more visible in the conventional XC cell test, inhibits plaque
      formation in the RadLV system. Substitution of X irradiation for UV exposure
      improved plaque visibility without loss of sensitivity.

PMID- 4353502
TI  - Variants of simian virus 40-transformed 3T3 cells that are resistant to
      concanavalin A.
AB  - By treating populations of simian virus 40 (SV40)-transformed 3T3 cells with
      concanavalin A, variants have been isolated which are resistant to the killing
      action of the lectin. The variants (i) resemble 3T3 cells morphologically and in
      some of their growth characteristics; (ii) are not agglutinated by high
      concentrations of concanavalin A or wheat germ agglutinin, but can be rendered
      agglutinable by treatment with low concentrations of trypsin; (iii) bind the same
      number of concanavalin A molecules as 3T3 or SV3T3 cells; (iv) cannot be
      transformed by SV40 and are resistant to focus formation after infection with
      murine sarcoma virus; (v) contain SV40-specific T antigen and RNA and; (vi) yield
      wild-type SV40 virus after heterokaryon formation with BS-C-1 cells.

PMID- 4353503
TI  - Transcription of simian virus 40. II. Hybridization of RNA extracted from
      different lines of transformed cells to the separated strands of simian virus 40
      DNA.
AB  - The amount of simian virus 40 (SV40) DNA present in various SV40-transformed
      mouse cell lines and "revertants" isolated from them was determined. The number
      of viral DNA copies in the different cell lines ranged from 1.35 to 8.75 copies
      per diploid quantity of mouse cell DNA and from 2.2 to 14 copies per cell. The
      revertants had the same number of viral DNA copies per diploid quantity of mouse
      cell DNA as their parental cell lines. (However, they showed an increased number
      of viral DNA copies per cell due to their increased amount of DNA.) By using
      separated strands of SV40 DNA, the extent of each DNA strand transcribed into
      stable RNA species was determined for the transformed and "revertant" cell lines.
      From 30 to 80% of the "early" strand and from 0 to 20% of the "late" strand was
      present as stable RNA species in the cell lines tested. There was no alteration
      in the pattern of the stable viral RNA species present in three concanavalin A
      selected revertants, whereas in a fluorodeoxyuridine-selected revertant there
      appeared to be less viral-specific RNA present in the cells.

PMID- 4353505
TI  - Simultaneous sudden death in infancy in identical twins.

PMID- 4353504
TI  - Relationship between replication of simian virus 40 DNA and specific events of
      the host cell cycle.
AB  - The relationship between replication of simian virus 40 (SV40) DNA and the
      various periods of the host-cell cycle was investigated in synchronized CV(1)
      cells. Cells synchronized through a double excess thymidine procedure were
      infected with SV40 at the beginning or the middle of S, or in G(2). The first
      viral progeny DNA molecules were in all instances detected approximately 20 h
      after release from the thymidine block, independent of the time of infection. The
      length of the early, prereplicative phase of the virus growth cycle therefore
      depended upon the period of the cell cycle at which the cells were infected.
      Infection with SV40 was also performed on cells obtained in early G(1) through
      selective detachment of cells in metaphase. As long as the cells were in G(1) at
      the time of infection, the first viral progeny DNA molecules were detected during
      the S period immediately following, whereas if infection took place once the
      cells had entered S, no progeny DNA molecule could be detected until the S period
      of the next cell cycle. These results suggest that the infected cell has to pass
      through a critical stage situated in late G(1) or early S before SV40 DNA
      replication can eventually be initiated.

PMID- 4353507
TI  - Experience with the Entamoeba histolytica fluorescent antibody test in Western
      Australia.

PMID- 4353506
TI  - Adrenocortical function and skin pigmentation in idiopathic haemochromatosis.

PMID- 4353508
TI  - Gas gangrene.

PMID- 4353509
TI  - [Radiological pictures of acute primary infectious broncho-pulmonary diseases].

PMID- 4353510
TI  - Histochemistry of nucleic acids and proteins in cells of neuroectodermal tumours
      of different grades of malignancy.

PMID- 4353511
TI  - Increase of EB virus positive cells in cultured Burkitt lymphoma cells after
      short-time exposure to heat.

PMID- 4353512
TI  - [The Niemann-Pick cell. Aspects in optical and ultrastructural cytology].

PMID- 4353513
TI  - Pleomorphic adenoma of the nasal septum.

PMID- 4353514
TI  - Dye staining of neural end-feed for light microscopy after glutaraldehyde
      fixation.

PMID- 4353515
TI  - Effects of adrenocorticotropic hormone and gonadotropins on urinary 17
      ketosteroid production in the male pseudohermaphrodite rat.

PMID- 4353516
TI  - Properties of mouse leukemia viruses. IV. Hemagglutination assay and
      characterization of hemagglutinating surface components.

PMID- 4353517
TI  - Properties of mouse leukemia viruses. V. Hemagglutination-inhibition and indirect
      hemagglutination tests.

PMID- 4353518
TI  - The membrane protein of influenza virus: extraction from virus and infected cell
      with acidic chloroform-methanol.

PMID- 4353519
TI  - The evolution of new species of viral DNA during serial passage of simian virus
      40 at high multiplicity.

PMID- 4353520
TI  - Two types of target cells for transformation with avian myelocytomatosis virus.

PMID- 4353521
TI  - Mapping of base sequence heterologies between genomes from different adenovirus
      serotypes.

PMID- 4353522
TI  - Preferential integration of simian virus 40 deoxyribonucleic acid into a
      particular size class of CV-1 cell deoxyribonucleic acid.

PMID- 4353523
TI  - Symmetrical in vivo transcription of polyoma DNA and the separation of self
      complementary viral and cell RNA.

PMID- 4353524
TI  - Picornavirus receptors and picornavirus multiplication in human-mouse hybrid cell
      lines.

PMID- 4353525
TI  - Nonproducer clones of murine sarcoma virus transformed guinea pig embryo cells.

PMID- 4353526
TI  - [Low density lipoproteins of the rat fetus].

PMID- 4353527
TI  - [Studies on rats with long-term resistance hypertension induced by daily
      administration of delayed-action preparations of angiotensin].

PMID- 4353529
TI  - [Convergence of septal and entorhinal afferences in neurons of the hippocampus
      formation].

PMID- 4353528
TI  - [Studies on the mechanism of action of peptides acting on smooth muscles. I.
      Isolation of a peptide binding cell fraction from muscles of the rat].

PMID- 4353530
TI  - Liquid scintillation counting of 14C- and 3H-labeled samples on solid supports: a
      general solution of the problem.

PMID- 4353531
TI  - A quantitative estimation of degree of purity of preparations of subcellular
      structures.

PMID- 4353532
TI  - Isolation of intact spinach chloroplasts in the CF-6 continuous-flow zonal rotor;
      implications for membrane-bound organelles.

PMID- 4353533
TI  - Detection of methanesulfonic acid in ethyl methanesulfonate.

PMID- 4353534
TI  - A sensitive and specific method for the measurement of monophosphoinositide at a
      microregional level in brain.

PMID- 4353535
TI  - An automated fluorescence method for determination of K+-dependent phosphatase.

PMID- 4353536
TI  - Fatty acid composition of neutral lipids and phospholipids of enamel and dentine
      from rat incisors and molars.

PMID- 4353538
TI  - Some developmental observations on the effects of prolonged deprivation of low
      voltage fast-wave sleep in the deermouse, Peromyscus maniculatus bairdi.

PMID- 4353537
TI  - The alveolar macrophage and its role in toxicology.

PMID- 4353539
TI  - The response of the multiple forms of lactate dehydrogenase to drugs.

PMID- 4353541
TI  - Further studies on the influence of steroids on viral infection in mice.
AB  - Certain steroids have been reported to enhance experimental viral infections,
      whereas others have little or no effect. Interference with the interferon system
      has been suggested as a possible mechanism for the viral infection-enhancing
      (VIE) activity of hormones. In the present study, steroids (prednisolone,
      progesterone, testosterone) which had no effect on MM virus infection
      demonstrated VIE activity against Mayaro virus infection. It is suggested that
      the VIE activity of a hormone may be dependent on the viral agent used for
      challenge. Data are also presented which suggest that, in addition to
      interference with the interferon system, the VIE activity of steroid hormones may
      be the result of at least two other actions: (i) alteration of cell membranes;
      (ii) stimulation of initial viral replication.

PMID- 4353540
TI  - Fatty acid profiles of cells from the insect cell line IPRL-21 (Spodoptera
      frugiperda) and of the tissue culture medium after repeated use.

PMID- 4353542
TI  - Neutralizing antibody response in bovine serum and nasal and salivary secretions
      after immunization with live or inactivated food-and-mouth disease virus.
AB  - Calves develop nasal and salivary neutralizing antibodies against foot-and-mouth
      disease virus after nasal inoculation with live virus. Nasal and salivary
      antibody was not detected after exposure to inactive virus. Serum antibodies were
      induced by live and inactive virus given subcutaneously. Passively acquired
      antibodies were detected as long as 7 months after birth.

PMID- 4353543
TI  - Studies of the antigenic relationships of the new human papovaviruses by electron
      microscopy agglutination.
AB  - Virus-antibody interactions observed by electron microscopy show that new human
      papovavirus isolates are antigenically distinct, but share common antigens.

PMID- 4353544
TI  - Analytical isotachophoresis in capillary tubes. Transformation of pyruvate to
      succinate by calf heart mitochondrial enzymes.

PMID- 4353547
TI  - Inferior venacavograms and renal venograms in the management of renal tumors.

PMID- 4353546
TI  - Polymorphonuclear leukocyte collagenase: localization in granules subjected to
      zonal centrifugation.

PMID- 4353545
TI  - Availability of magnesium: balance studies in rats with various inorganic
      magnesium salts.

PMID- 4353548
TI  - Increasing sensitivity rates of urinary gram-negative bacilli to antimicrobials.

PMID- 4353549
TI  - Arteriography of Wilms tumor.

PMID- 4353550
TI  - Regulation of levels of guanosine cyclic 3',5'-monophosphate in the central
      nervous system: effects of depolarizing agents.

PMID- 4353551
TI  - Thyrotoxic periodic paralysis. Function of sarcoplasmic reticulum and muscle
      glycogen.

PMID- 4353552
TI  - Neurologic manifestations in tropical sprue. A clinical and electrodiagnostic
      study.

PMID- 4353553
TI  - Effect of Mg++ on neuromuscular transmission in the Eaton-Lambert syndrome.

PMID- 4353554
TI  - Correlative insulin and glucagon secretion of the perfused rat pancreas following
      pituitary peptides.

PMID- 4353555
TI  - Early effects of testosterone on phospholipid metabolism in the seminal vesicles
      of immature rats.

PMID- 4353556
TI  - Cyclic AMP and gastrointestinal hormones. Studies in isolated pancreatic islets.

PMID- 4353557
TI  - Differences in the age-dependent development and sexual differentiation of
      soluble and membrane-bound activities of 3alpha- and 3beta-hydroxysteroid
      dehydrogenase in rat liver.

PMID- 4353558
TI  - Long-term ADH-treatment of rats with genetic diabetes insipidus.

PMID- 4353559
TI  - In vivo "radioimmunoassay" of aldosterone in rats.

PMID- 4353560
TI  - A simple and sensitive radioimmunoassay for plasma angiotensin II.

PMID- 4353561
TI  - Response of plasma aldosterone to various stimuli in the angiotensin II-immune
      rabbit.

PMID- 4353562
TI  - Relationships between weight changes and renin, aldosterone, estrogens and
      progesterone in cyclical edema.

PMID- 4353563
TI  - PTH-infusion and estimation of urinary cAMP in hyperparathyroidism.

PMID- 4353564
TI  - Suppression and stimulation of plasma testosterone and DHT in hirsute women.

PMID- 4353566
TI  - Lipolytically active peptides from hog pituitary glands.

PMID- 4353565
TI  - Differential diagnosis of female hirsutism, Cushing's and Conn's syndrome.
      Quantitative sequential scintigraphy of the adrenals with 131-J-19
      iodocholesterol.

PMID- 4353567
TI  - Fine structure of corticotrophic cells and of pituitary adenomas in Cushing's
      syndrome.

PMID- 4353568
TI  - Isolated pituitary cells: ACTH secretion and synthesis.

PMID- 4353569
TI  - Contribution on regulation of corticotrophic partial function. Reference to an
      active negative regulation.

PMID- 4353570
TI  - Human pharmacological studies with a new synthetic corticotrophic peptide
      consisting of 18 amino acids.

PMID- 4353572
TI  - Cortisol, cortisone, and corticosterone in plasma following ACTH-stimulation
      during the first 6 hours of life.

PMID- 4353571
TI  - ACTH determinations before and after selective removal of pituitary adenomas in
      Nelson's syndrome.

PMID- 4353573
TI  - Studies on cyclic adenosine 3':5' monophosphate concentrations in human cervical
      mucus.

PMID- 4353574
TI  - Species differences in luteinizing hormone as infered from slope variations in a
      radioligand receptor assay.

PMID- 4353575
TI  - Radioligand receptor assay for the determination of LH and HCG activities
      utilizing rat ovarian receptors.

PMID- 4353576
TI  - Dihydrotestosterone receptor in human mammary cancer.

PMID- 4353577
TI  - Interrelationship of two microsomal estrogen receptor molecules.

PMID- 4353578
TI  - In-vitro corticosteroid synthesis in rat adrenals. I. Results indicating (an)
      alternative pathway(s) of synthesis without the intermediates cholesterol,
      pregnenolone and progesterone.

PMID- 4353579
TI  - The influence of ACTH and HCG on the steroidogenesis of fetal adrenals in vitro.

PMID- 4353580
TI  - Pathways of carbohydrate metabolism in Tetrahymena. Subcellular distribution and
      properties of hexokinase, aldolase and alpha-glycerophosphate dehydrogenase.

PMID- 4353581
TI  - Oscillatory glycolysis in yeast: the pattern of phase resetting by oxygen.

PMID- 4353582
TI  - Bull semen nicotinamide adenine dinucleotide nucleosidase. IV. Nonpolar
      interactions of inhibitors with the substrate binding site.

PMID- 4353583
TI  - ESR probing of macromolecules: spin-labeling of the active sites of the
      proteolytic serine enzymes.

PMID- 4353584
TI  - ESR probing of macromolecules: spin label study of the conformational integrity
      and transitions in modified alpha-chymotrypsin.

PMID- 4353585
TI  - Mechanism of action of a respiratory inhibitor from the gill tissue of the
      sporulating common mushroom, Agaricus bisporus.

PMID- 4353586
TI  - [Critical view on intra-animal culture of microorganisms, a method for the
      detection of chemically-induced mutations].

PMID- 4353587
TI  - A study of postoperative cytostatic medication in patients with operable
      carcinoma of the lung.

PMID- 4353588
TI  - Comparison of the effects of two phosphodiesterase inhibitors, theophylline and
      papaverine, on blood glucose, plasma FFA and glycerol in the rat.

PMID- 4353589
TI  - [New type of paramagnetic nitrosyl complexes of non-heme iron].

PMID- 4353590
TI  - [Phototransformation of free radicals in polycrystalline proteins due to UV
      radiation. Formation of peptide group radicals].

PMID- 4353591
TI  - [Study of the conformational states of endoplasmic membranes by the method of
      molecular probes].

PMID- 4353592
TI  - [Model of signal processing in neuron assemblies of glomerulus type in the
      lateral geniculate body of the visual system].

PMID- 4353593
TI  - Ocular pathology of GM2 gangliosidosis--Type 2 (Sandhoff's disease).

PMID- 4353594
TI  - Cyclic AMP inhibition of cytotoxin ("lymphotoxin") elaboration by stimulated
      lymphocytes.

PMID- 4353595
TI  - [Double-fiber ribonucleic acid in the treatment of viral dermatoses].

PMID- 4353596
TI  - Calcium metabolism at the cellular level.

PMID- 4353597
TI  - Electron microscopy of endothelial and epithelial components of the lungs:
      correlations of structure and function.

PMID- 4353598
TI  - Mechanism of action of cytochrome c oxidase and its implications for energy
      conservation.

PMID- 4353599
TI  - Electron transfer across membranes and energy coupling.

PMID- 4353601
TI  - Nucleic acids. 14. Synthesis and antiviral activity of some 5'-esters of 9-beta-D
      arabinofuranosyladenine (ara-A).

PMID- 4353603
TI  - Uptake of androgen analogs by prostate tissue.

PMID- 4353602
TI  - Factors that influence the antagonistic properties of angiotensin II antagonists.

PMID- 4353604
TI  - A synthesis of noformycin.

PMID- 4353605
TI  - Seromucoid and albumin levels in maternal and cord serum in relation to obstetric
      stress.

PMID- 4353606
TI  - Cattle and Culicoides biting midges as possible overwintering hosts of bluetongue
      virus.

PMID- 4353607
TI  - Cytomegalovirus: conversion of nonpermissive cells to a permissive state for
      virus replication.
AB  - Human embryonic kidney cells are epithelioid cells which are normally
      nonpermissive for in vitro replication of human cytomegalovirus. These cells were
      converted to a permissive state for the virus by prior treatment with 5-iodo-2'
      deoxyuridine. When this method was used, a nonpermissive cell was made permissive
      to an infecting virus.

PMID- 4353608
TI  - [Experiences with expanded after care].

PMID- 4353609
TI  - [Antibodies to parainfluenza virus serotype 3 in cattle].

PMID- 4353610
TI  - [Inhibiting action of an elective medium for E. coli on gram-positive
      microflora].

PMID- 4353611
TI  - [Endotoxinemia and adrenocortical hemorrhage. Experimental study using ACTH
      treated rats].

PMID- 4353600
TI  - Utilization of somatic cell hybrids for genetic studies in man.

PMID- 4353612
TI  - [Diseases in man and animal caused by Clostridium perfringens and their
      relations].

PMID- 4353614
TI  - [Some sulfonated derivatives of pyridine. Synthesis and anti-inflammatory
      activity].

PMID- 4353613
TI  - I-cell disease, mucolipidosis II. Pathological, histochemical, ultrastructural
      and biochemical observations in four cases.

PMID- 4353615
TI  - [A trace antibiotic component of viomycin].

PMID- 4353616
TI  - Technetium-99m labelled pyrophosphate: a simple and reproducible bone scanning
      agent.

PMID- 4353617
TI  - Virological studies in Reiter's disease.

PMID- 4353618
TI  - Characterization of genital strains of Herpesvirus hominis.

PMID- 4353619
TI  - Sexual transmission of intestinal parasites.

PMID- 4353620
TI  - Progress in myasthenia gravis.

PMID- 4353622
TI  - Ultrastructure of cysts of E. histolytica.

PMID- 4353621
TI  - Hypothesis: breast cancer regression under oestrogen therapy.
AB  - Recent reports have thrown doubt on both of the major mechanisms which have been
      suggested for the regression of breast cancer under high-dosage oestrogen therapy
      a direct effect on binding sites and an indirect inhibition of prolactin release.
      A searching review on the clinical response of 407 patients with advanced breast
      cancer treated by oestrogen therapy under my direction showed certain anomalies,
      including age determined tumour inhibition and stimulation, dose dependence of
      tumour inhibition and stimulation, differential site sensitivity, and tumour
      regression with oestrogen withdrawal. The hypothesis usually postulated to
      explain these anomalies is that the tumour may in the same individual be composed
      of multiple genetically distinct clones of cells. It is suggested instead that
      the effect of high-dosage oestrogen therapy in breast cancer may depend
      critically on the absolute and relative concentrations of prolactin and oestrogen
      actively available at the tumour. On this basis the clinical manifestation of
      tumour stimulation in response to oestrogen administration suggests that the
      oestrogen concentration at the target is inadequate. Differences in site
      sensitivity in the same patient may depend on tumoral factors such as the level
      of oestradiol and prolactin binding receptors in the tissue.

PMID- 4353623
TI  - Ultrastructure of E. histolytica--strain NIH 200.

PMID- 4353624
TI  - Specific binding of (3H) lysine-vasopressin to pig kidney plasma membranes.
      Relationship of receptor occupancy to adenylate cyclase activation.

PMID- 4353625
TI  - Studies on the mechanism of action of the gal repressor.

PMID- 4353626
TI  - Mechanism of activation of a cyclic adenosine 3':5'-monophosphate
      phosphodiesterase from bovine heart by calcium ions. Identification of the
      protein activator as a Ca2+ binding protein.

PMID- 4353627
TI  - Studies on calciferol metabolism. 8. Evidence for a cytoplasmic receptor for 1,25
      dihydroxy-vitamin D3 in the intestinal mucosa.

PMID- 4353629
TI  - Succinic semialdehyde dehydrogenase from a Pseudomonas species. II. Physical and
      immunochemical properties of the enzyme.

PMID- 4353628
TI  - Succinic semialdehyde dehydrogenase from a Pseudomonas species. I. Purification
      and chemical properties.

PMID- 4353630
TI  - The oxidation of catechols by reduced flavins and dehydrogenases. An electron
      spin resonance study of the kinetics and initial products of oxidation.

PMID- 4353632
TI  - Kinetic studies on the substrate reduction of xanthine oxidase.

PMID- 4353631
TI  - The kinetics and mechanism of reduction of electron transfer proteins and other
      compounds of biological interest by dithionite.

PMID- 4353633
TI  - Steroid structure and androgenic activity. Specificities involved in the receptor
      binding and nuclear retention of various androgens.

PMID- 4353634
TI  - Receptors for thyrotropin-releasing hormone in prolactin producing rat pituitary
      cells in culture.

PMID- 4353635
TI  - Stimulatory and inhibitory effects of guanyl nucleotides on fat cell adenylate
      cyclase.

PMID- 4353636
TI  - Estrogen receptor in a human cell line (MCF-7) from breast carcinoma.

PMID- 4353637
TI  - Inhibition of cellular differentiation by phospholipase C. I. Effects of the
      enzyme on myogenesis and chondrogenesis in vitro.
AB  - In cell culture, a partially purified commercial preparation of phospholipase C
      (PLC) from Clostridium welchii inhibited fusion of myoblasts at concentrations of
      12-50 microg per ml. At lower concentrations, PLC-treated cultures were
      indistinguishable from controls, and at concentrations above 100 microg per ml,
      PLC-treated cells detached from their substrates. The effect was reversible and
      fusion resumed approximately one cell cycle time after removal of the enzyme.
      Neither the percent of cells in the mitotic cycle nor the duration of the
      different phases of the cycle were altered by PLC at concentrations which
      inhibited fusion. Cell motility was not reduced by the enzyme. Unfused, PLC
      treated myoblasts were virtually indistinguishable in ultrastructure from
      untreated cells just before fusion. In the presence of PLC, mononucleated
      myogenic cells did not synthesize thick (150 A) filaments. Treatment of culture
      medium with insolubilized commercial PLC did not abolish the capacity of the
      medium to support myogenesis. Chondrocytes treated with PLC divided repeatedly
      but failed to synthesize metachromatic matrix and failed to incorporate labeled
      sulfate into chondroitin sulfate. PLC was further purified by chromatography on
      Sephadex G-100. The resulting preparation was free of detectable protease,
      yielded one band on SDS-acrylamide gel electrophoresis, and displayed all of the
      biological activities of the less pure material.

PMID- 4353640
TI  - A radioimmunoassay for beta-melanocyte-stimulating hormone in human plasma.

PMID- 4353638
TI  - Establishment and characterization of ethidium bromide resistance in simian virus
      40-transformed hamster cells. Effects on mitochondria in vivo.
AB  - This study describes the isolation and subsequent characterization of four
      mammalian cell lines resistant to ethidium bromide (EB). Treatment of the simian
      virus 40- (SV40) transformed hamster cell line F5-1 first led to the
      establishment of the F2 cell line, which is resistant to 2 microg EB/ml. At this
      concentration cytochromes c and b are present in almost normal or only slightly
      diminished amounts, whereas cytochromes a + a(3) show an obvious decrease. The
      mitochondria of the F2 cell show a normal ultrastructure, not distinct from the
      parental cell line F5-1, and contain closed circular DNA. The sensitive parental
      F5-1 cells, however, when exposed to the same dye concentration exhibit the
      typical EB-induced ultrastructural changes in the mitochondria, and no more
      component I mitochondrial DNA can be demonstrated. 1 yr after establishment we
      derived from the F2 cell three more cell lines, resistant against 4, 8, and 16
      microg of EB/ml. These cell lines, termed F4, F8, and F16, respectively, also
      revealed relatively intact-appearing mitochondria, although distinguishable from
      F5-1 and F2 mitochondria by a more condensed or unorthodox cristae conformation.
      F4, F8, and F16 cell lines contained closed circular mitochondrial DNA in the
      same position as that of the parental F5-1 cells, when analyzed in an isopycnic
      CsCl-EB gradient. A small shoulder at the lower density side of the DNA I peaks
      was observed. The newly acquired drug resistance of the F cells is hereditarily
      transmitted to the progeny cells and retained even after a period of growth in EB
      free medium.

PMID- 4353639
TI  - Embryonic chick intestine in organ culture. A unique system for the study of the
      intestinal calcium absorptive mechanism.
AB  - Duodena from 20-day-old chick embryos can be maintained in large scale organ
      culture on specially designed stainless-steel grids in contact with serum-free
      medium for 48 h with excellent preservation of mucosal structure at both the
      light and electron microscope levels. Although mitotic rate was subnormal,
      several other factors attest to the essential viability of the cultured
      intestine: L-leucine incorporation into protein, as well as the synthesis of a
      specific vitamin D(3)-induced calcium-binding protein (CaBP), increased over a 48
      h culture period, and the electropotential gradient across the intestine was
      maintained throughout the culture period as was a concentration gradient for
      calcium. The tissue responded to vitamin D(3) in the medium by synthesizing the
      calcium-binding protein within 6 h and by exhibiting enhanced (45)Ca uptake
      within 12-24 h. Concentrations of vitamin D(3), or its 25-hydroxylated
      derivative, higher than necessary for CaBP induction, also increased the activity
      of alkaline phosphatase. The 1,25-dihydroxylated derivative of vitamin D(3), at a
      level extremely potent in CaBP induction, did not stimulate alkaline phosphatase.
      Mucosal to serosal transport of (45)Ca could also be measured in everted duodenal
      sacs, subsequent to culture under similar conditions, and was also increased by
      vitamin D(3) in the medium. Other embryonic organs, esophagus, stomach, liver,
      pancreas, lung, skin, and muscle, did not produce CaBP in response to vitamin
      D(3) in the culture medium. However, CaBP-synthesizing capacity was present in
      the entire intestinal tract, exclusive of the rectum. (59)Fe and (32)P uptake by
      cultured duodenum were also stimulated by vitamin D(3). The system has proven
      quite useful in the study of the vitamin D-mediated calcium absorptive mechanism
      but should be applicable to the study of the absorption of other nutrients,
      drugs, hormones, etc., as well as other studies of intestinal function.

PMID- 4353641
TI  - Incorporation of 32P into phospholipids of the hypothalamo-neuro-hypophysial
      system and subcellular distribution of labelled phospholipids in the rat neural
      lobe.

PMID- 4353642
TI  - Distribution of fructose, citric acid, sialic acid and lipids in male accessory
      glands of the hamster, Mesocricetus auratus.

PMID- 4353643
TI  - The influence of carbon dioxide on the growth of obligate and facultative
      anaerobes on solid media.

PMID- 4353645
TI  - Intracellular growth and type variation of Neisseria gonorrhoeae in tissue cell
      cultures.

PMID- 4353644
TI  - Resistotyping of Shigella sonnei.

PMID- 4353646
TI  - Estimation of the concentration of low density lipoprotein cholesterol and very
      low density lipoprotein cholesterol by selective adsorption from serum with
      magnesium compounds.

PMID- 4353647
TI  - Effect of thyrotropin and of LATS on mouse thyroid cyclic AMP.

PMID- 4353648
TI  - Monolayer culture of a human pancreatic beta-cell adenoma.

PMID- 4353649
TI  - [Bone scintigraphy. Technic, indications, results].

PMID- 4353650
TI  - Mutations affecting growth of the Escherichia coli cell under a condition of DNA
      polymerase I-deficiency.

PMID- 4353651
TI  - [Mechanism of action of glucocorticoids].

PMID- 4353652
TI  - [Jugular chemodectoma].

PMID- 4353653
TI  - Subfornical organ: site of drinking elicitation by angiotensin II.
AB  - Angiotensin II applied directly to the subfornical organ in a dose as small as
      0.1 nanogram elicited short-latency drinking behavior in water-sated rats.
      Lesions in the body of this structure blocked drinking induced by angiotensin II
      applied to the basal telencephalon (including preoptic area). These results call
      attention to the subfornical organ as an important central nervous structure
      involved in the conrol of drinking behavior.

PMID- 4353654
TI  - Familial gouty malignant uric acid lithiasis due to mutant
      phosphoribosylpyrophosphate synthetase.

PMID- 4353655
TI  - [Passive hemagglutination reaction for the identification of the foot-and-mouth
      disease virus].

PMID- 4353656
TI  - [Specific cell resistance induced by foot-and-mouth disease virus].

PMID- 4353657
TI  - [Immune ascites fluids for typing the foot-and-mouth disease virus].

PMID- 4353658
TI  - [Detection of the foot-and-mouth disease virus in animal slaughter products].

PMID- 4353659
TI  - Nitrogen transformations in soils. I. In sandy soil under barley and peanut in a
      two years' rotation.

PMID- 4353660
TI  - Nitrogen transformation in soils. II. In sandy soil under horse-bean and sesame
      in a two years' rotation.

PMID- 4353661
TI  - Centrally induced drinking: comparison of angiotensin II- and carbachol-sensitive
      sites in rats.

PMID- 4353662
TI  - pH dependence of reversal potential for acetylcholine-induced currents in
      neurons.

PMID- 4353663
TI  - Spontaneous cytomegalovirus mononucleosis. Clinical and laboratory observations
      in nine cases.

PMID- 4353664
TI  - Cytomegalovirus infection in previously healthy adults.

PMID- 4353665
TI  - Adrenal ablation by venous catheter.

PMID- 4353666
TI  - Effect of ionophorous antibiotics (nigericin, gramicidin and valinomycin) on
      cyclic AMP synthesis in rat adipose tissue.

PMID- 4353667
TI  - Effect of highly specific inhibitors of oxidative phosphorylation,
      dicyclohexylcarbodiimide, antimycin A and piercidin A, on cyclic AMP accumulation
      induced by noradrenaline and theophylline in rat adipose tissue.

PMID- 4353668
TI  - Inhibition of hypoxanthine transport by chlorpromazine and SKF 525-A in cell
      culture.

PMID- 4353669
TI  - Formation of nucleotides of (6-14C)allopurinol and (6-14C)oxipurinol in rat
      tissues and effects on uridine nucleotide pools.

PMID- 4353670
TI  - Interactions of acetaldehyde, ethyl alcohol and oxybarbiturates affecting
      mitochondrial functions.

PMID- 4353672
TI  - Bilateral patellar metastases from carcinoma of the male breast.

PMID- 4353671
TI  - Effect of ethoxyquin on the carbon tetrachloride-induced changes in rat hepatic
      microsomal enzymes.

PMID- 4353673
TI  - [Synthesis of SV 40 tumor antigen in cells with inhibited cell division].

PMID- 4353674
TI  - [Syndrome of minimal peripheral nerve dysfunction].

PMID- 4353675
TI  - [Epidemiological study of intracranial tumors in North Moravia].

PMID- 4353676
TI  - [Lampbrush chromosomes and amphinucleoli in oocyte nuclei of the snail Bithynia
      tentaculata L].

PMID- 4353677
TI  - [Teased-fiber study of peripheral neuropathy--relation between fiber diameter and
      Ranvier internodal length].

PMID- 4353680
TI  - Psychiatric aftercare clinic effectiveness as a function of patient demographic
      characteristics.

PMID- 4353678
TI  - Equine coital exanthema in the United Kingdom.

PMID- 4353679
TI  - Diagnosing the state of the diagnostic function: an analysis of the literature.

PMID- 4353681
TI  - [Effect of angiotensin II on autotransplanted kidney].

PMID- 4353683
TI  - Spare gonadotrophin receptors in rat testis.

PMID- 4353682
TI  - Identification of a critical period during the S phase for activation of the
      Epstein-Barr virus by 5-iododeoxyuridine.

PMID- 4353684
TI  - EB viral genomes in epithelial nasopharyngeal carcinoma cells.

PMID- 4353685
TI  - [Growth of transplantable chrysoidinc-induced hepatoma in castrated mice].

PMID- 4353687
TI  - Motor nerve conduction velocity and electromyogram in chronic lead poisoning.

PMID- 4353686
TI  - [Chemical modification of blood flow].

PMID- 4353688
TI  - Congenital hemihypertrophy with oligophrenia. Genetic and Dermatoglyphic data,
      muscle structural and ultrastructural aspects. (Report of a case).

PMID- 4353689
TI  - [Inactivation of the foot-and-mouth disease virus by methylglyoxal].

PMID- 4353690
TI  - [Protein and ribonucleic acid biosynthesis in the cells in the replication of the
      foot-and-mouth disease virus].

PMID- 4353691
TI  - [Antigenic properties of the foot-and-mouth disease virus concentrated by
      polyethylene glycol].

PMID- 4353694
TI  - [Electron microscopic studies of pinocytosis and of the synthesis of polyoma
      virus in cell cultures].

PMID- 4353693
TI  - Improved hemagglutination inhibition assay for mammary tumor virus antigen.
AB  - It is our experience that the use of sheep red blood cells pretreated with
      formaldehyde and pyruvaldehyde before sensitizing with viral antigen yields
      results that are comparable to that obtained by using the tannic acid method. The
      double aldehyde method provides the added advantage of being useful for assaying
      the viral antigen content in substances which contain high levels of interfering
      substances which would preclude the use of other assay methods.

PMID- 4353692
TI  - Assay methods for Clostridium perfringens type A enterotoxin.
AB  - Enterotoxin produced by a sporulating culture of Clostridium perfringens type A
      NCTC 8798 was purified to a level of 3,500 mouse mean lethal doses per mg of
      nitrogen. High-titer sera were obtained from rabbits injected with enterotoxin
      and used to compare the sensitivity of serological tests and bioassays for C.
      perfringens enterotoxin. Reversed passive hemagglutination was by far the most
      sensitive test, followed by microslide diffusion, single gel diffusion and
      electroimmunodiffusion, guinea pig skin test, mouse test, and rabbit ileal loop
      test.

PMID- 4353696
TI  - The role of phospholipids in TSH stimulation of adenylate cyclase in thyroid
      plasma membranes.

PMID- 4353695
TI  - Studies on the postnatal development of responses of hepatic histidase to
      endocrine control.

PMID- 4353697
TI  - Evidence for a peptidic factor in spermatozoa inhibiting the ovarian maturation.

PMID- 4353698
TI  - The chemotactic effect of 5'-amido analogues of adenosine cycle 3',5'
      monophosphate in the cellular slime moulds.

PMID- 4353699
TI  - The role of the anion-binding site of transferrin in its interaction with the
      reticulocyte.

PMID- 4353700
TI  - The physical chemistry of hemes and hemopeptides. I. Physiochemical properties
      and reduction of chlorodeuterohemin in organic solvent.

PMID- 4353701
TI  - Distribution of glutamine hexosephosphate aminotransferase in rat tissues;
      changes with state of differentiation.

PMID- 4353702
TI  - Phosphatidyldiglucosyl diglyceride from Streptococci and its relationship to
      other polar lipids.

PMID- 4353703
TI  - Phospholipids of a moderately halophilic halotolerant bacterium. Isolation and
      identification of glucosylphosphatidylglycerol.

PMID- 4353705
TI  - Synthesis in vivo of phospholipids of liver mitochondria and endoplasmic
      reticulum from glycerol and fatty acids.

PMID- 4353704
TI  - [Possible unmasking of noradrenaline receptors by linoleic acid-rich
      phospholipids in fat cell membranes. II. Adenylate cyclase and phosphodiesterase
      activities].

PMID- 4353706
TI  - The response of diphosphoinositide and triphosphoinostitide to perturbations of
      the adenylate energy charge in cells of Saccharomyces cerevisiae.

PMID- 4353708
TI  - A method for the determination of the initial rate of reaction of lecithin:
      cholesterol acyltransferase in human plasma.

PMID- 4353707
TI  - The exchange of phospholipids between plasma lipoproteins and rapidly dividing
      human cells grown in tissue culture.

PMID- 4353709
TI  - Uncoiling and protein cleavage of paramyxovirus nucleocapsid after incubation
      with ribosomes in vitro.

PMID- 4353711
TI  - Gaucher-like cells and congenital dyserythropoietic anaemia, type II (HEMPAS).

PMID- 4353710
TI  - Studies on bovine pancreatic deoxyribonuclease A. II. The effect of different
      bivalent metals on the specificity of degradation of DNA.

PMID- 4353712
TI  - Effect of isopropyl methane sulphonate (IMS) on haemopoietic colony-forming
      cells.

PMID- 4353713
TI  - Considerations in the radiation therapy of Wilms' tumor.

PMID- 4353714
TI  - Treatment of Wilms' tumor and factors affecting prognosis.

PMID- 4353715
TI  - Wilms' tumor--an interdisciplinary treatment program with and without
      dactinomycin.

PMID- 4353716
TI  - Serial catecholamines in the radiation management of children with neuroblastoma.

PMID- 4353718
TI  - Type 3 hyperlipoproteinaemia and sinking prebeta lipoprotein.

PMID- 4353717
TI  - Some nonspecific morphological changes in neuromuscular diseases.

PMID- 4353719
TI  - Release factor regulating termination of complete protein in a eukaryotic
      organism.

PMID- 4353720
TI  - Association of polyadenylic acid with messenger RNA of vesicular stomatitis
      virus.

PMID- 4353721
TI  - Self-annealing of 4 S strands from replicating simian virus 40 DNA.

PMID- 4353722
TI  - The storage and release of transmitter substances from Helix neurones.

PMID- 4353723
TI  - Effects of various secretagogues upon 42K and 22NA uptake during in vitro hormone
      release from the rat adenohypophysis.
AB  - 1. The in vitro uptake of (22)Na and (42)K was measured simultaneously in rat
      adenohypophyses during hormone release produced by several secretagogues and
      during inhibition of hormone release in Ca-free media.2. Intracellular
      adenohypophysial [Na(+)] and [K(+)] changed only slightly when the uptake
      changed. This would indicate that relative permeability changes were the primary
      effect of the treatments.3. The uptake of (42)K was increased by elevated
      external [K(+)], but was unaffected by the presence or absence of Ca(2+). Acid
      extracts of hypothalamus-stalk-median eminence or cerebellum also increased the
      (42)K uptake.4. The uptake of (22)Na or (24)Na was decreased by elevated [K(+)].
      Uptake was increased in Ca-free Krebs-Ringer bicarbonate; but was unaltered when
      [K(+)] was concurrently increased.5. Neither purified growth hormone releasing
      hormone, synthetic lysine-vasopressin, dibutyryl cyclic AMP nor theophylline had
      an effect on the uptake of either K(+) or Na(+).6. The rapid uptake of (22)Na and
      its smaller volume of distribution compared to absolute measurements of
      intracellular [Na(+)] suggest that the plasma membrane of adenohypophysial cells
      is relatively impermeable to Na(+).7. We conclude that changes in the uptake of
      Na(+) and K(+) associated with hormone release are incidental to the release
      process.8. Hormone release produced by elevated external [K(+)] is most likely
      due to a non-specific increase in permeability of the cell membranes,
      facilitating Ca(2+) entry into the cytoplasm.9. The results suggest that the low
      resting transmembrane potentials of adenohypophysial cells may be due to their
      conjoint relatively high permeability to both K(+) and Ca(2+), rather than K(+)
      and Na(+).

PMID- 4353724
TI  - Renal vasodilation and the antinatriuretic effect of angiotensin in the rat.

PMID- 4353725
TI  - Individualization of angiotensin receptors in smooth muscle cell membranes.

PMID- 4353726
TI  - The effect of divalent cations on angiotensin stimulation of fluid transport by
      rat colon.

PMID- 4353727
TI  - Evidence for two corticosteroid receptor mechanisms in the feedback control of
      corticotrophin secretion.

PMID- 4353728
TI  - Mechanism of excitation of uterine smooth muscle. Changes in ionic fluxes induced
      by angiotensin.

PMID- 4353729
TI  - The physiological role of prostaglandins in parturition.

PMID- 4353730
TI  - Effects of intrafollicular injection of hormones and drugs.

PMID- 4353732
TI  - -Autoradiography of 10B compound distribution in tissue by use of superimposition
      technique.

PMID- 4353731
TI  - Nature, role and control of the gonadotrophins.

PMID- 4353733
TI  - [Repercussion of the portal injection of ultrafluid Lipidol in hepatic cellular
      microrespiration].

PMID- 4353734
TI  - [A rare type of association of glomus tumors--tumor of the glomus jugulare and
      paraganglioma of the pneumogastric nerve. Angiographic aspect; therapeutic
      problems].

PMID- 4353736
TI  - [Roentgenological study of the parotid glands under conditions of double
      contrasting].

PMID- 4353737
TI  - [Studies on the prevention of milk fever in dairy cattle by oral administration
      of vitamin D3].

PMID- 4353735
TI  - Hepatitis B antigenemia. Clinical implications.

PMID- 4353738
TI  - [Diagnostical difficulties and possibilities in the determination of adenovirus
      infections during epidemics of acute respiratory tract].

PMID- 4353739
TI  - [Experiences with the use if Iruxol ointment in burns].

PMID- 4353740
TI  - Pituitary and gonadal function in hypogonadotrophic hypogonadism.

PMID- 4353741
TI  - Hypothalamic-pituitary-adrenal function in patients with pituitary tumours.

PMID- 4353742
TI  - The effect of dihydroergotamine on ACTH-stimulated lipolysis in rat adipocytes.

PMID- 4353743
TI  - Evidence for the internal feedback phenomenon in human subjects: effects of ACTH
      on plasma CRF.

PMID- 4353744
TI  - Differential action of parathyroid and thyroid hormones on effective intestinal
      absorption of calcium. In vivo studies with 47calcium in rats.

PMID- 4353745
TI  - Oestriol conjugates in amniotic fluid. Qualitative and quantitative aspects,
      including preliminary studies in Rh isoimmunization.

PMID- 4353746
TI  - Inhibition of the noradrenaline-induced adenyl cyclase stimulation by augmented
      alpha-adrenergic response in subcutaneous adipose tissue from hypothyroid
      subjects.

PMID- 4353747
TI  - Review of treatment of Meniere's syndrome.

PMID- 4353748
TI  - The effect of betahistine hydrochloride in Meniere's disease.

PMID- 4353749
TI  - The effect of Serc (betahistine hydrochloride) on the circulation of the inner
      ear in experimental animals.

PMID- 4353750
TI  - Meniere's disease: subjective and objective evaluation of medical treatment with
      betahistine HCl.

PMID- 4353751
TI  - A study of the efficacy of betahistine in Meniere's syndrome.

PMID- 4353752
TI  - Factors influencing the cure rate in nephroblastoma. A review of 335 cases.

PMID- 4353753
TI  - [Neurolysis in the post-traumatic phase].

PMID- 4353754
TI  - [Sympathetic ophthalmia and antilymphocyte serum].

PMID- 4353755
TI  - Formation of the native structure of proteins: inferences from the kinetics of
      denaturation and renaturation.

PMID- 4353756
TI  - Mechanisms in the chemical syntheses of polypeptides and polynucleotides.

PMID- 4353757
TI  - The kinetics of transmitter release in myasthenia gravis. II. An
      electrophysiological analysis of the replenishment of transmitter stores.

PMID- 4353758
TI  - [Titer of antibodies against Burkitt's lymphoma virus in Burkitt's lymphoma and
      other diseases].

PMID- 4353759
TI  - [Oncogenesis by herpesvirus].

PMID- 4353760
TI  - [Definition of the methods for propagation of the virus of herpes simplex
      (herpesvirus hominis) in cell cultures].

PMID- 4353761
TI  - [The role of herpesvirus hominis type 2 as a possible causative factor in
      cervical carcinoma].

PMID- 4353762
TI  - [Perspectives for the treatment of hydatidiform mole and chorionic epithelioma].

PMID- 4353763
TI  - Metabolic abnormalities in asthma--decreased urinary cycle AMP.

PMID- 4353764
TI  - Adjuvant induced formation of lysophosphatides and their role in the immune
      response.

PMID- 4353765
TI  - The effects of adjuvants and stress on the production of IgE antibody in rats.

PMID- 4353766
TI  - Studies on surface antigens of mammalian cells.

PMID- 4353767
TI  - The relationship between the viruses causing hepatitis and autoimmunity in liver
      disease.

PMID- 4353768
TI  - Studies on the mechanism of T lymphocyte-mediated cytolysis.

PMID- 4353769
TI  - The mechanism of action of macrophage migration inhibitory factor (MIF).

PMID- 4353770
TI  - Immunological properties of carbohydrate and protein fractions of Timothy grass
      pollens.

PMID- 4353771
TI  - Cerebrocortical adenyl cyclase activity following neonatal thyroid hormone
      deficiency.

PMID- 4353772
TI  - Enhanced effects of prostaglandin E1 and dibutyryl cyclic AMP upon human
      lymphocytes in the presence of cortisol.
AB  - The combined effects of cortisol and agents acting through a cyclic AMP-mediated
      mechanism have been studied in cultures of highly purified human peripheral
      lymphocytes. Incubation with prostaglandin E(1) (PGE(1)), dibutyryl cyclic AMP,
      or cortisol results in a concentration-dependent inhibition of [(3)H]-thymidine
      incorporation by both unstimulated and phytohemagglutinin (PHA)-stimulated
      lymphocytes, and PHA-induced morphologic transformation is prevented. When
      cortisol and PGE(1) (or dibutyryl cyclic AMP) are added together to lymphocyte
      cultures, enhanced inhibitory effects are observed. Incubation of unstimulated or
      PHA-stimulated lymphocytes with PGE(1) results in an elevation of intracellular
      cyclic AMP levels within 20 min. The concentration of cyclic AMP gradually
      returns to base-line levels over a 1-6 h period of time. Cortisol alone does not
      significantly alter cyclic AMP concentrations. However, incubation with PGE(1) in
      the presence of cortisol results in a greater stimulation of intracellular cyclic
      AMP levels than that observed with PGE(1) alone. These findings suggest that
      cortisol may act synergistically with PGE(1) to elevate lymphocyte cyclic AMP
      levels and to regulate [(3)H]thymidine incorporation and transformation.

PMID- 4353773
TI  - Mechanism of the hypolipemic effect of clofibrate in postabsorptive man.
AB  - Splanchnic metabolism of triglycerides and other major substrates was studied in
      the postabsorptive state in normotriglyceridemic and hypertriglyceridemic human
      subjects who received (1/2) g of clofibrate four times daily for 3 wk. Transport
      in blood plasma of triglycerides produced in the splanchnic region was quantified
      by three methods: (a) measurement of the transsplanchnic gradient of (14)C
      labeled triglycerides during constant intravenous infusion of [1- (14)C]
      palmitate (b) chemical measurement of the transplanchnic gradient in
      concentration of triglycerides of very low density lipoproteins; and (c)
      determination of clearance of (14)C-labeled triglycerides in extrasplanchnic
      tissues. The first method measures only triglycerides derived from free fatty
      acids and the last two measure total splanchnic production. In
      hypertriglyceridemic subjects treated with clofibrate, average rates of total
      splanchnic production of triglycerides and production from free fatty acids were
      the same as those of comparable untreated subjects despite a consistent fall in
      plasma triglyceride levels. The hypotriglyceridemic effect of the drug was
      therefore accompanied by improved disposal of triglycerides in extrasplanchnic
      tissues. In treated normotriglyceridemic subjects, unlike their untreated
      counterparts, total splanchnic production was significantly higher than
      production from free fatty acids. Failure of clofibrate to reduce triglyceride
      levels in normotriglyceridemic subjects may have been related to increased total
      splanchnic production, coupled with improved extrasplanchnic disposal. Systemic
      transport and net splanchnic uptake of free fatty acids were similar in treated
      and control subjects but the fraction of [1-(14)C]palmitate converted to
      acetoacetate in splanchnic tissues was significantly higher in treated subjects.
      Net splanchnic extraction of plasma amino acids that enter the glucogenic pathway
      via pyruvate was increased in treated subjects and their arterial concentrations
      were reduced.

PMID- 4353774
TI  - Hypoxanthine-guanine phosphoribosyltransferase variant associated with
      accelerated purine synthesis.
AB  - We have previously described a 14-yr-old boy with hyperuricemia, renal failure,
      and accelerated purine production resistant in vivo and in vitro to purine
      analogs. This patient demonstrated normal red cell hypoxanthine-guanine
      phosphoribosyltransferase (HPRT) heat stability, electrophoresis at high pH, and
      activity at standard substrate levels. In the present report an abnormal HPRT
      enzyme was demonstrated by enzyme kinetic study with phosphoribosylpyrophosphate
      (PRPP) as the variable substrate and inhibitory studies with sodium fluoride.
      Apparently normal HPRT activity in a patient with hyperuricemia and gout does not
      exclude a functionally significant HPRT mutation.

PMID- 4353776
TI  - Circadian rhythm of plasma aldosterone concentration in patients with primary
      aldosteronism.
AB  - Plasma aldosterone, cortisol, and renin activity were measured in nine recumbent
      patients with hyperaldosteronism, including seven with adenomas, one with
      idiopathic hyperplasia, and one with glucocorticoid suppressible hyperplasia. All
      had peak values of plasma aldosterone concentration from 3 a.m. to noon and
      lowest values at 6 p.m. or midnight. This rhythm was similar to the circadian
      pattern of plasma cortisol in the same patients. When these data were normalized
      to eliminate the wide variation in ranges of plasma aldosterone and cortisol
      between individuals, there was an excellent correlation (r = + 0.87, P < 0.005)
      between the two hormones. In contrast, plasma aldosterone concentrations did not
      correlate with plasma renin activity before or after normalization of data. Short
      term suppression of ACTH by administration of dexamethasone eliminated the
      circadian variation of plasma aldosterone in both patients with hyperplasia and
      in four of five patients with adenomas, while it markedly altered the rhythm in
      the fifth. Similar doses of dexamethasone were administered to four normal
      subjects and did not flatten the circadian rhythm of plasma aldosterone. These
      data suggest that patients with primary aldosteronism have a circadian rhythm of
      plasma aldosterone mediated by changes in ACTH.

PMID- 4353775
TI  - Maturation of responsiveness to cardioactive drugs. Differential effects of
      acetylcholine, norepinephrine, theophylline, tyramine, glucagon, and dibutyryl
      cyclic AMP on atrial rate in hearts of fetal mice.
AB  - Freshly isolated hearts of fetal mice of gestational ages ranging between 12 and
      22 days (term) were exposed to several concentrations of a variety of
      chronotropic agents. Acetylcholine (10(-4)-10(-2) M) caused marked bradycardia in
      all hearts, even after only 12-14 days' gestation (i.e., even before cardiac
      innervation had occurred), and the intensity of the response increased steadily
      with advancing age throughout gestation. Responsiveness to norepinephrine was
      present but minimal at 12-14 days, so that mean atrial rate rose by < 10% with a
      maximal concentration of the drug (10(-5) M); responsiveness became more marked
      by 15-16 days (just after the time atrial innervation is thought to begin) and
      still greater effects appeared just before term. Glucagon had no effect in hearts
      of < 17 days' gestational age, but caused tachycardia thereafter, indicating that
      cardiac responsiveness to glucagon differentiates later than does responsiveness
      to norepinephrine. Responses to theophyl-line in 12-14 day hearts exceeded those
      to norepinephrine, indicating that the drug can affect heart rate independently
      of its ability to cause release of endogenous catecholamines. In contrast,
      tyramine caused no response until 21-22 days, well after the time the beta
      receptor has differentiated and after innervation is fairly well developed,
      suggesting that the drug's primary sympathomimetic effect is indirect rather than
      direct. Dibutyryl cyclic AMP did not cause tachycardia at any fetal age. It is
      concluded that maturation of responsiveness of the mouse heart to cardioactive
      drugs develops in specific patterns for different agents. The identification of
      differential patterns of maturation for various drugs may provide valuable means
      for characterizing the differentiation of specific receptors and for
      investigating possible mechanisms of action of the drugs.

PMID- 4353778
TI  - [Cyclic AMP--a metabolic regulator of life ranging from bacteria to higher
      animals].

PMID- 4353777
TI  - Cyclic AMP and sodium transport. Quantitative and temporal relationships in toad
      urinary bladder.
AB  - The effects of oxytocin upon tissue cAMP content and short-circuit current (SCC)
      were measured in the urinary bladder of the toad, Bufo marinus. Tissue cAMP
      levels doubled before any increment in SCC was observed, the two hormone
      responses were quantitatively related, and a threshold level for an effect of
      cAMP upon sodium transport was demonstrated. The period of time over which cAMP
      levels continued to rise after the threshold level had been attained seemed
      invariant with hormone concentration. The rate at which cAMP levels rose
      increased with hormone concentration yielding hormone concentration-dependent
      maximal levels. The decay of cAMP levels was delayed when sodium influx was
      curtailed, suggesting a sodium-regulatory effect upon tissue cAMP levels.

PMID- 4353779
TI  - [Germination and heat resistance of bacterial spores].

PMID- 4353780
TI  - [Immunological study of fish using the toxin of Clostridium perfringens].

PMID- 4353781
TI  - [Evaluation of the rapid ACTH test and blood cortisol determination by
      fluorescence method in hepatobiliary diseases].

PMID- 4353782
TI  - Infection with herpes-simplex viruses 1 and 2. II.

PMID- 4353783
TI  - The chemotherapy of viral infections.

PMID- 4353784
TI  - Potassium, angiotensin and the dual control of aldosterone secretion.

PMID- 4353785
TI  - Endocrine complications of malignancy.

PMID- 4353786
TI  - Clinical and epidemiologic clues to the diagnosis of respiratory infections.

PMID- 4353787
TI  - [Glomic and pseudo-glomic tumors. Clinical and therapeutic aspects].

PMID- 4353789
TI  - [X-ray manifestations of pigmented villonodular synovitis].

PMID- 4353788
TI  - Herpes viruses and cancer.

PMID- 4353790
TI  - [X-ray characteristics of calcification in malignant synovioma].

PMID- 4353791
TI  - Immunohistological, microscopical and neurochemical studies on encephalitides. 7.
      Subacute sclerosing panencephalitis. Susceptibility of dogs to the virus, and
      characterization of host response.

PMID- 4353792
TI  - Differential sensitivity of virulent and attenuated strains of type 1 poliovirus
      to polyethylene glycol as a possible new genetic marker.

PMID- 4353794
TI  - Haemadsorption-negative assay of rubella virus in baby hamster kidney cells.

PMID- 4353793
TI  - Differential growth of MHV (PRI) and MHV (C3H) in genetically resistant C3H mice
      rendered susceptible by eperythrozoon infection.

PMID- 4353795
TI  - The isolation and partial characterization of a herpesvirus from a case of bovine
      metritis.

PMID- 4353796
TI  - Ultrastructural examination of phytohemagglutinin stimulated lymphocytes infected
      with vesicular stomatitis virus.

PMID- 4353797
TI  - Genetic studies of respiratory syncytial virus temperature-sensitive mutants.

PMID- 4353799
TI  - Multiplication of the virus of epizootic haemorrhagic disease of deer in
      culicoides species (Diptera, Ceratopogonidae).

PMID- 4353798
TI  - Electron microscopic studies of respiratory syncytial temperature-sensitive
      mutants.

PMID- 4353800
TI  - Elevation of the intracellular levels of cyclic adenosine monophosphate during in
      vitro infection of transmissible gastroenteritis virus. Brief report.

PMID- 4353801
TI  - Location of Rous sarcoma viral structural polypeptides on the virion surface.
      Brief report.

PMID- 4353802
TI  - Effects of hycanthone on rapidly proliferating cells.

PMID- 4353803
TI  - Preservation of structural integrity of liver lysosomes and membrane-stabilizing
      action of anti-inflammatory drugs, catecholamines and cyclic adenosine
      monophosphate in isotonic salt media.

PMID- 4353804
TI  - Effects of quinidine on some reactions and ion translocations catalyzed by the
      Na+, K+ -ATPase complex.

PMID- 4353805
TI  - Leukokinin-forming system in the ascitic fluid of a murine mastocytoma.

PMID- 4353806
TI  - Carbohydrate metabolism in the plasmodium of the myxomycete Physarum flavicomum.

PMID- 4353807
TI  - [Significance of lipoprotein-X and serum cholinesterase in preoperative diagnosis
      of obstructive jaundice].

PMID- 4353808
TI  - Plasma enzyme levels and erythrocyte G6P-DH activity in ducks and chicken.

PMID- 4353809
TI  - Isolation and some characteristics of liver plasma membranes from rainbow trout.

PMID- 4353810
TI  - Intermediary metabolism in Dicrocoelium dendriticum (Trematoda).

PMID- 4353811
TI  - Metabolism in porifera. I. Some studies on the biosynthesis of fatty acids,
      sterols and bromo-compounds by the sponge Verongia aerophoba.

PMID- 4353812
TI  - Characterization of ubiquinone from vegetative amoebae and mature sorocarps of
      the cellular slime mold, Dictyostelium discoideum.

PMID- 4353813
TI  - Identification of astaxanthin in Scottish salmon.

PMID- 4353814
TI  - The management of oral ulceration.

PMID- 4353816
TI  - [Behavior of the circadian rhythm of adrenal cortex secretion in anorexia nervosa
      in relation to the duration of amenorrhea].

PMID- 4353815
TI  - Growth hormone regulation and hypothalamic-pituitary-adrenal function in anorexia
      nervosa.

PMID- 4353817
TI  - [Adrenal glycoative function in congestive heart failure. I. Changes in blood and
      urinary cortisol and the ACTH loading test].

PMID- 4353818
TI  - Characterization of an avian reovirus isolated in Queensland.

PMID- 4353820
TI  - Latent herpes simplex virus in the central nervous system of rabbits and mice.
AB  - Herpes simplex virus (HSV) type 1 induces a long-standing latent infection in the
      central nervous system of mice and rabbits. The infection was extablished in the
      brain stems of rabbits after corneal inoculation of the virus, and in the spinal
      cords of mice after rear footpad infection. In these animals, infectious virus
      could not be recovered by direct isolation from tissues; it was detected only
      after the tissues were maintained as organ cultures in vitro.

PMID- 4353819
TI  - Cytostatic elimination of syngeneic rat tumor cells in vitro by nonspecifically
      activated macrophages.
AB  - Syngeneic tumor cell lines induced in inbred DA rats by polyoma virus,
      dimethylbenzanthracene, or methylcholanthrene were interacted in vitro with
      syngeneic effector cells. Glycogen-induced peritoneal exudate cells,
      predominantly polymorphonuclear leukocytes, and proteose peptone-induced
      peritoneal cells, principally macrophages, were the effector cells employed.
      Activated, nonimmune macrophages or exudative polymorphonuclear leukocytes
      produced pronounced morphological changes in syngeneic tumor cells as evidenced
      by a substantial reduction in tumor cell numbers and appearance of shrunken
      cells, even though there was no increase in cell debris. Polymorphonuclear
      leukocytes exerted a generally similar but quantitatively much diminished effect.
      These effector cells constantly produced a decrease in the incorporation by tumor
      cells of DNA precursors such as [(3)H]thymidine and of RNA precursors such as
      [(3)H]uridine. In this regard, the effector cells were quite refractory to high
      doses of X-irradiation. Interaction of target cells with activated, nonimmune
      macrophages yielded low but consistent signs of cytotoxicity, whereas
      polymorphonuclear leukocytes gave no such effects. Elimination of functional
      macrophages by silica, an agent specifically toxic for macrophages, resulted in
      unrestricted tumor cell proliferation despite continued generation of
      cytotoxicity. Accordingly, cytostatic mechanisms appear to play a predominant
      role in the elimination of tumor cells by nonimmune phagocytes. Evidence from a
      variety of experimental approaches suggest that the cytostatic effect is
      dependent on cell-to-cell contact.

PMID- 4353822
TI  - Stimulation of glucose-6-phosphatase activity in the mucosal cells of the mouse
      intestine.

PMID- 4353821
TI  - A characterization of nucleoside diphosphatase in the onion root tip.

PMID- 4353823
TI  - Ultrastructural comparison of transformed human cells and their normal
      counterparts at various passage levels.

PMID- 4353824
TI  - [Primary cylindroma of lacrimal gland].

PMID- 4353826
TI  - Technical problems with agarose-hormone linkage.

PMID- 4353825
TI  - Infection with herpes-simplex viruses 1 and 2. 1.

PMID- 4353828
TI  - Primary visual experience and secondary cognitive elaboration in stage REM: a
      modest confirmation and an extension.

PMID- 4353827
TI  - The male as a reservoir of infection with cytomegalovirus, herpes and mycoplasma.

PMID- 4353829
TI  - Sleep learning and progressive blurring of perception during sleep.

PMID- 4353830
TI  - Actions of glucagon and dibutyryl cyclic 3',5'-AMP on chronotropic responses to
      vagal stimulation and acetylcholine.

PMID- 4353831
TI  - Localization of the cyclic AMP system in the arterial wall.

PMID- 4353832
TI  - The morphological consequences and the significance of cytomegalovirus infection
      in renal transplant patients.

PMID- 4353833
TI  - A method for inducing unilateral silicosis in rabbits by an injection technique
      with some observations on lung clearance and quantitative evaluation of
      experimental silicosis.

PMID- 4353834
TI  - Early effects of quartz and titanium dioxide dust on pulmonary function and
      tissue. An experimental study on rabbits.

PMID- 4353835
TI  - [Study on the collagenase activity of oral strains of Bacteroides
      melaninogenicus].

PMID- 4353836
TI  - [The neurogenic tumors of the face and jaws].

PMID- 4353837
TI  - [Frey's syndrome. Cases].

PMID- 4353838
TI  - Glomus jugulare tumors: effect of irradiation.

PMID- 4353839
TI  - The isolation and transmission of the virus of infectious bovine rhinotracheitis
      infectious pustular vulvo-vaginitis.

PMID- 4353840
TI  - Diagnosis of mixed infections with myxovirus influenzae A equi 2 and herpes virus
      equi 1 among Danish stud horses.

PMID- 4353841
TI  - The role of the platelet membrane in platelet function. I. Blood coagulation.

PMID- 4353842
TI  - Benign mixed mesodermal tumors of the uterus: a histogenetic study.

PMID- 4353843
TI  - Agar plate dilution method for routine antibiotic susceptibility testing in a
      hospital laboratory.

PMID- 4353844
TI  - Antacids before obstetric anaesthesia. A clinical evaluation of the effectiveness
      of mist. magnesium trisilicate BPC.

PMID- 4353845
TI  - The locus of pathogenicity of asbestos dust: a theory.

PMID- 4353846
TI  - Terminal innervation ratio in neuromuscular disease. I. Methods and controls.

PMID- 4353847
TI  - Terminal innervation ratio in neuromuscular disease. II. Disorders of lower motor
      neuron, peripheral nerve, and muscle.

PMID- 4353848
TI  - Herpesvirus hominis encephalitis. Virus isolation from brain biopsy in seven
      patients and results of therapy.

PMID- 4353849
TI  - The use of chronic catheterization techniques in foetal sheep.

PMID- 4353851
TI  - Neuromuscular junction defect in diabetes.

PMID- 4353850
TI  - Enhanced release of insulin by prostaglandins in isolated pancreatic islets.

PMID- 4353852
TI  - Protein synthesis in the rat anterior pituitary. 3. The fate of total protein,
      prolactin and growth hormone labeled in an in vitro incubation.

PMID- 4353853
TI  - Estrogen receptor in a prolactin secreting pituitary tumor (MtTW5).

PMID- 4353854
TI  - Electrically stimulated ACTH release in pharmacologically blocked rats.

PMID- 4353855
TI  - An increase of thyroid hormone secretion in response to excess iodide in rats
      treated with thyroxine.

PMID- 4353856
TI  - Role of microtubules in basal and stimulated release of growth hormone and
      prolactin in rat adenohypophysis in vitro.

PMID- 4353857
TI  - Influence of alpha- and beta-subunits on the kinetics of formation and activity
      of native and hybrid molecules of LH and human chorionic gonadotropin.

PMID- 4353859
TI  - [Modifications of the gas chromatographic pattern of urinary corticosteroids
      induced by various doses of beta 1-24 corticotropin].

PMID- 4353858
TI  - Corticosteroidogenesis and its relation to ACTH dependence of mitochondrial
      components.

PMID- 4353860
TI  - [Influence of the protein level of the diet on some effects of amaranth and
      butter yellow in the rat].

PMID- 4353861
TI  - The toxicology of dieldrin (HEOD). I. Long-term oral toxicity studies in mice.

PMID- 4353862
TI  - Metabolism of Aflatoxin B1 by the guinea-pig.

PMID- 4353864
TI  - Hepatoblastoma in children.

PMID- 4353863
TI  - Pulmonary adenomatosis in guinea pigs exposed to coal dust inhalation.

PMID- 4353865
TI  - An experimental Wilms' tumor suitable for therapeutic and biologic studies. II.
      The inhibition of renal compensatory hypertrophy by a transplantable tumor.

PMID- 4353866
TI  - [Study of the wetting and drying processes in capsular and non capsular forms of
      Cryptococcus albidus var. diffluens by the NMR-spin echo methods].

PMID- 4353867
TI  - The effects of gamma irradiation on the structure and reactivity of native and
      cross-linked collagen fibres.

PMID- 4353868
TI  - Characterization of invertase activity from cariogenic Streptococcus mutans.
AB  - Invertase activity from Streptococcus mutans GS-5 has been partially purified and
      shown to possess beta-fructofuranosidase specificity. The enzyme has a broad pH
      optimum between pH 5.5 and 7.5 and exhibits maximal activity at 37 C. Fructose,
      but not the glucose analogue alpha-methyl-d-glucoside, acts as a competitive
      inhibitor of the enzyme. None of the common glycolytic intermediates or adenine
      nucleotides had any significant effect on enzyme activity. A molecular weight of
      approximately 47,000 was estimated for the enzyme. The enzyme does not appear to
      be catabolically repressed by glucose nor inducible by sucrose. Higher specific
      activities of the enzyme are observed in fructose or glucose-grown cells compared
      to sucrose-grown cells. These results are discussed in terms of the regulation of
      invertase activity in vivo.

PMID- 4353869
TI  - Physiological effects of menaquinone deficiency in Bacillus subtilis.
AB  - Several aspects of the respiratory physiology of a mutant of Bacillus subtilis
      deficient in menaquinone-7 (MK-7) and in cytochromes were investigated. The
      mutant, an aromatic amino acid auxotroph blocked at dehydroshikimate reductase,
      is unable to synthesize MK-7 unless grown in the presence of the common aromatic
      amino acid intermediate, shikimate. The inability to synthesize MK-7 prevents the
      mutant from expressing the normal postexponentialphase cytochrome phenotype. When
      grown in the presence of shikimate, normal levels of these electron transport
      components are formed. It was found that the intracellular concentration of MK-7
      could be predictably regulated by growing the cells with known concentrations of
      exogenous shikimate. When the mutant was grown under conditions where MK-7
      biosynthesis was severely limited, there was a decrease in oxygen uptake and in
      membrane-associated reduced nicotinamide adenine dinucleotide (NADH) oxidase and
      succinate oxidase activity. NADH oxidase, but not succinoxidase, could be
      restored in membrane preparations by the addition of menadione to the reaction
      mixture. Reduced-minus-oxidized cytochrome difference spectra indicate that an MK
      7 deficiency limits electron flow through the cytochrome chain. Furthermore,
      oxidation-reduction patterns suggest that MK-7 functions between the primary
      dehydrogenases and the cytochromes. Although the mutant is asporogenous when
      grown under conditions where MK-7 biosynthesis is limited, the inability to
      sporulate does not appear to result from lesions in the electron transport
      system.

PMID- 4353870
TI  - Isolation of a mutant of Escherichia coli defective in cytosine-specific
      deoxyribonucleic acid methylase activity and in partial protection of
      bacteriophage lambda against restriction by cells containing the N-3 drug
      resistance factor.
AB  - A mutant (designated mec(-)) of Escherichia coli F(+) 100 endo I(-)su(+) r(K) (
      )m(K) (+) has been isolated which is defective in cytosine-specific
      deoxyribonucleic acid (DNA) methylase activity. The DNA of this mutant, as well
      as the DNA of phages lambda and fd propagated in it, is virtually devoid of 5
      methyl-cytosine (MeC); in contrast, the mutation has no significant effect on the
      level of N(6)-methyladenine in DNA. Phage lambda grown on the mec(-) mutant is
      more strongly restricted by N-3-containing cells than is lambda grown on the
      mec(+) parent. These results suggest that methylation of certain cytosine
      residues by the E. coli K-12 enzyme partially protects lambda DNA from either the
      N-3 restriction nuclease or against secondary degradation subsequent to N-3
      specific degradation. Analysis of the MeC level in viral and cellular DNA
      obtained from mec(+), mec(+) (m(N3) (+)), and mec(-) (m(N3) (+)) strains has led
      to the conclusion that the R-factor controlled DNA-cytosine methylase may be
      capable of methylating a sequence(s) which is a substrate for the K-12 enzyme.

PMID- 4353872
TI  - Studies on mitochondria membrane proteins in Saccharomyces cerevisiae under
      different degrees of glucose repression.
AB  - Mitochondrial membrane proteins synthesized in vivo in the presence of
      cycloheximide were analyzed on electrofocusing polyacrylamide gels. Five of the
      six protein bands observed have their isoelectric points below pH 7. The six
      proteins are not synthesized when both cycloheximide and chloramphenicol are
      present, and they are absent in a petite mutant lacking mitochondrial
      deoxyribonucleic acid (DNA), leading to the conclusion that the proteins are
      synthesized on mitochondrial ribosomes. By labeling cells of Saccharomyces
      cerevisiae cultivated in a chemostat under different degrees of glucose
      limitation, the effect of glucose repression on the synthesis of the
      mitochondrial membrane proteins was determined. Two of the protein bands showed a
      relatively reduced synthesis under the strongest glucose repression tested. The
      specific activity of the cytochrome oxidase and the percentage of mitochondrial
      DNA in the total DNA were found to be influenced at a lower level of glucose
      repression.

PMID- 4353871
TI  - Effects of ethylenediaminetetraacetate and chloramphenicol on mitochondrial
      activity and morphogenesis in Mucor rouxii.
AB  - The present study demonstrates the importance of mitochondrial activities in
      controlling Mucor rouxii morphogenesis. The respiratory capacity of the spores of
      this facultatively anaerobic, dimorphic fungus becomes repressed if germination
      and growth take place in the absence of oxygen. The level of activity of
      mitochondrial enzymes such as cytochrome oxidase and malate dehydrogenase is
      lower in the anaerobic yeastlike cells than it is in ungerminated spores and in
      aerobic hyphae, but the reverse is true for glycolytic enzymes such as pyruvate
      kinase and alcohol dehydrogenase. Following exposure to air, yeastlike cells
      convert into hyphae after a lag period corresponding to aerobic adaptation.
      Anaerobic cultures grown in the presence of ethylenediaminetetraacetate (EDTA) at
      a concentration of 10(-4) M exhibit hyphal morphology. These cells, which are
      fully adapted to anaerobic fermentation, nevertheless have potentially active
      mitochondria with the same levels of respiratory enzymes as ungerminated spores.
      These cells are able to grow immediately after aeration, without an adaptation
      lag. Evidence is presented which indicates that the morphogenetic effect of EDTA
      is not the result of elimination of free metals. Additional evidence proving
      mitochondrial control of morphogenesis in M. rouxii is that chloramphenicol (4
      mg/ml) induced the formation of respiratory-deficient, yeastlike cells in aerobic
      cultures.

PMID- 4353873
TI  - Regulation of aspartokinase activity in Clostridium perfringens.
AB  - Cells of Clostridium perfringens type D apparently possess only a single species
      of aspartokinase. This enzyme has been partially purified and shown to be
      feedback inhibited by meso-diaminopimelate in an allosteric manner. The inhibitor
      exerts its action noncompetitively with respect to both substrates. The kinetic
      analysis further indicates that no homotropic cooperative interactions occur
      between either multiple substrate or inhibitor sites. Like aspartokinases from
      other bacteria, the clostridial enzyme is stimulated by the presence of either
      potassium or ammonium cations. A molecular weight of 102,000 was estimated for
      the enzyme following gel-filtration chromatography. Enzyme activity remains
      relatively constant throughout the growth cycle of the organism even well into
      the stationary growth phase. These results are discussed in terms of the role of
      the enzyme in the growth of the organism.

PMID- 4353874
TI  - Cross-feeding of Escherichia coli mutants defective in the biosynthesis of
      nicotinamide adenine dinucleotide.
AB  - Mutants of Escherichia coli defective in the biosynthesis of nicotinamide adenine
      dinucleotide (NAD) are able to grow in a Casamino Acids medium lacking NAD and
      its immediate precursors, nicotinic acid and nicotinamide. This property has
      allowed the development of a system to measure cross-feeding between a nadA and a
      nadB mutant. This system provides a means of isolating the intermediate,
      prequinolinic acid, as well as a biological assay for the compound. The nadB
      mutant feeds the nadA mutant, indicating that the nadA enzyme occurs first in the
      pathway and the nadB enzyme second. No cross-feeding was detected between nadA
      and nadC or between nadB and nadC.

PMID- 4353876
TI  - Factors in the identification of human skeletal remains.

PMID- 4353875
TI  - The gua operon of Escherichia coli K-12: evidence for polarity from guaB to guaA.
AB  - Guanine auxotrophs of Escherichia coli K-12 were isolated after mutagenesis with
      N-methyl-N'-nitro-N-nitrosoguanidine, ethyl methane sulfonate, or the acridine
      mustard ICR 372. guaA (xanthosine 5'-monophosphate [XMP] aminase-less) mutants
      were distinguished from guaB (inosine 5'-monophosphate [IMP] dehydrogenase-less)
      mutants by their growth response to xanthine and by enzyme assay. Mutations were
      classified as base substitutions or frameshift on the basis of mutagen-induced
      reversion patterns. All guaA strains, including three frameshift mutants,
      produced derepressed levels of IMP dehydrogenase when cultured with a growth
      limiting concentration of guanine. The guaB strains were of two types: (i) those
      producing derepressed levels of XMP aminase, and (ii) those producing basal
      levels of XMP aminase when grown under conditions of guanine starvation. In the
      guaB strains of the second type, the expression of the adjacent guaA gene is
      reduced. It is proposed that this pleiotropic effect of some guaB mutations is a
      result of polarity. The orientation of polarity suggests the gene order
      "operator"-guaB-guaA. Gel diffusion studies with IMP dehydrogenase antiserum
      showed that strains carrying polar guaB mutations do not produce cross-reacting
      material (CRM). The remaining guaB mutants were either CRM(+) or CRM(-). Mapping
      the mutations by three-factor crosses showed that polar and nonpolar guaB sites
      are clustered in a small genetic region cotransducible with guaA. The relative
      positions of the guaB mutational sites established that the polar mutations lie
      within the structural gene for IMP dehydrogenase.

PMID- 4353878
TI  - The effect of synthetic peptide on chronic renal hypertension in the rat.

PMID- 4353877
TI  - Elevated circulating renin activity in rats following doses of cadmium known to
      induce hypertension.

PMID- 4353879
TI  - Cord-blood low-density lipoprotein cholesterol: estimation versus measurement
      with the preparative ultracentrifuge.

PMID- 4353881
TI  - The nature of the granules within sulcular epithelial cells.

PMID- 4353880
TI  - A dual precipitation method for quantitative plasma lipoprotein measurement
      without ultracentrifugation.

PMID- 4353882
TI  - Hycanthone-induced hepatic changes in mice infected with Schistosoma mansoni.

PMID- 4353883
TI  - Adrenergic-adenosine 3',5'-monophosphate regulation of serotonin N
      acetyltransferase activity and the temporal relationship of serotonin N
      acetyltransferase activity synthesis of 3H-N-acetylserotonin and 3H-melatonin in
      the cultured rat pineal gland.

PMID- 4353884
TI  - Comparative study of the action of phenothiazine and para-fluorobutyrophenone
      derivatives on rat brain membranes using the spin label technique.

PMID- 4353885
TI  - Renin-angiotensin system in human hypertension due to segmental renal ischemia.

PMID- 4353886
TI  - Enhancement of the inotropic action of glucagon by small concentration of
      angiotensin.

PMID- 4353887
TI  - Ultrastructure of a human chorionic gonadotropin-and adrenocorticotropin
      responsive functioning Sertoli-Leydig cell tumor (type I).

PMID- 4353888
TI  - Bursa-dependent and thymus-dependent "surveillance" of a virus-induced tumour in
      the chicken.

PMID- 4353889
TI  - Fucosylglycolipid metabolism in oncornavirus-transformed cell lines.

PMID- 4353890
TI  - Oestrogenic stimulation of macromolecular synthesis is correlated with nuclear
      hormone-receptor complex in neonatal rat uterus.

PMID- 4353891
TI  - Variations among sublines of inbred AKR mice.

PMID- 4353892
TI  - The intestinal flora of pigs with special reference to Clostridium perfringens.

PMID- 4353893
TI  - Secretion of growth hormone in the rat.

PMID- 4353894
TI  - Prostaglandin receptors in the hamster uterus during the estrous cycle.

PMID- 4353895
TI  - [Ammonia, glycogen and Porter-Silber chromogens in peripheral blood in cases of
      alcoholic delirium].

PMID- 4353896
TI  - Correlation between measures of the rapid eye movements of wakefulness and sleep.

PMID- 4353897
TI  - REM sleep interruption: experimental shortening of REM period duration.

PMID- 4353898
TI  - [Oxidation-reduction properties of aryl derivatives of triazole and tetrazole and
      their effect on the free-radical state of animal tissues].

PMID- 4353900
TI  - Brain tumor types induced by the Schmidt-Ruppin strain of Rous sarcoma virus in
      inbred Fischer rats.

PMID- 4353899
TI  - Light and electron microscopic studies of mouse CNS after subcutaneous
      administration of the E and M variants of the encephalomyocarditis virus.

PMID- 4353901
TI  - [Congenital hypophosphatasia and odontogenesis].

PMID- 4353902
TI  - Tear flow in man.

PMID- 4353903
TI  - The effects of methoxyflurane on sympathetic ganglionic transmission.

PMID- 4353904
TI  - [Contribution of the indirect fluorescence technic to the immunological diagnosis
      of human cysticercosis].

PMID- 4353905
TI  - Interrelationship between the kinds of dietary carbohydrate and fat in
      hyperlipoproteinemic patients. 1. Sucrose and starch with polyunsaturated fat.

PMID- 4353906
TI  - Interrelationship between the kinds of dietary carbohydrate and fat in
      hyperlipoproteinemic patients. 2. Sucrose and starch with mixed saturated and
      polyunsaturated fats.

PMID- 4353907
TI  - Interrelationship between the kinds of dietary carbohydrate and fat in
      hyperlipoproteinemic patients. 3. Synergistic effect of sucrose and animal fat on
      serum lipids.

PMID- 4353908
TI  - Effect of dietary starches on the serum, aorta and hepatic lipid levels in
      cholesterol-fed rats.

PMID- 4353909
TI  - Plasma phospholipids in type IV hyperlipoproteinemia.

PMID- 4353911
TI  - Phase transitions in lipids.

PMID- 4353910
TI  - Effect of a hypolipidaemic drug (CH 13,437) on plasma and tissue lipids, and on
      the intravenous fat tolerance in man.

PMID- 4353912
TI  - Motion of spin labeled fatty acids in membrane structures.

PMID- 4353913
TI  - Membrane lipid pattern and non-electrolytes permeability in Salmo trutta L. red
      blood cells.

PMID- 4353914
TI  - [Structure-activity relationships in acetylcholinesterase reactivators inhibited
      by organophosphorus compounds. IV. N-hydroxyimidazole-3-oxides and their
      quaternary salts].

PMID- 4353915
TI  - Inhibitory effect of chick interferon and interferon inducer (rI:rC) on the
      induction of cellular DNA synthesis and transformation of chick embryo
      fibroblasts infected in culture with Rous sarcoma virus.

PMID- 4353916
TI  - [Current views and prospects about the interactions between catecholamines and
      sex hormones in the regulation of the secretion of gonadotropins].

PMID- 4353918
TI  - Sperm velocity and morphology in 1727 ejaculates with normal sperm count.

PMID- 4353917
TI  - The prevention of postoperative pelvic adhesions following conservative operative
      treatment for human infertility. A final 3-year follow-up report.

PMID- 4353919
TI  - Plasma LH-HCG, 17 -estradiol, estrone and progesterone monitoring around
      ovulation and subsequent nidation.

PMID- 4353920
TI  - Penetration of spermatozoa into the uterine mucosa: a possible cause of
      infertility in the human.

PMID- 4353921
TI  - Clomifen in the treatment of anovulatory women.

PMID- 4353922
TI  - Sonographic visualization of coexisting gestation sac and I.U.D. in the uterus
      and a consideration of a causative factor of accidental pregnancy.

PMID- 4353924
TI  - Reactions between nitroxyls and radiation-induced long-lived DNA-transients.

PMID- 4353923
TI  - The effect of synthetic luteinizing hormone-releasing hormone on blood levels of
      luteinizing hormone and follicle stimulating hormone in Klinefelter patients.

PMID- 4353925
TI  - H-adduct radicals in x-irradiated frozen solutions of uracil derivatives.

PMID- 4353926
TI  - Radical yield in x-irradiated biological molecules. I. Glycine.

PMID- 4353927
TI  - Role of cyclic AMP in mitogen induced transformation of human peripheral
      leukocytes.

PMID- 4353928
TI  - The pathogenesis of corneal inflammation due to Herpes simplex virus. I. Corneal
      hypersensitivity in the rabbit.

PMID- 4353929
TI  - Neutralizing antibodies to Epstein-Barr virus in healthy populations and patients
      with infectious mononucleosis.

PMID- 4353930
TI  - Herpesvirus hominis infection in newborn mice. I. An experimental model and
      therapy with iododeoxyuridine.

PMID- 4353931
TI  - Experimental animal model for encephalitis due to herpes simplex virus.

PMID- 4353932
TI  - Isolation of herpesviruses from trigeminal ganglia of man, monkeys, and cats.

PMID- 4353933
TI  - Viruses causing common respiratory infections in man. II. Enteroviruses and
      paramyxoviruses.

PMID- 4353935
TI  - Relation between the reaction cytochrome oxidase-oxygen and oxygen uptake in
      cells in vivo. The role of diffusion.

PMID- 4353934
TI  - The role of water in the origin of life and its function in the primitive gene.

PMID- 4353936
TI  - [Essential hereditary shrinking of the conjunctive associated with multiple
      malformations].

PMID- 4353937
TI  - [Functional disorders of the optic nerve in patients on oral contraceptives].

PMID- 4353938
TI  - [Effect of vasoactive drugs on intra-ocular pressure].

PMID- 4353940
TI  - [Adrenoviral conjunctivitis, keratoconjunctivitis].

PMID- 4353941
TI  - Infection with herpes-simplex viruses 1 and 2. 3.

PMID- 4353942
TI  - Virus specific surface antigen in cells productively infected with polyoma virus.

PMID- 4353939
TI  - [Posttraumatic orbital meningocele].

PMID- 4353943
TI  - Intracranial tumors of apoplectiform onset.

PMID- 4353944
TI  - Resistance of rabbit corneal epithelium to herpes simplex virus.

PMID- 4353945
TI  - [Role of collagen in the pathogenesis of rheumatoid arthritis].

PMID- 4353947
TI  - Immunosuppression and virus infections.

PMID- 4353946
TI  - Bacterial infections in immunosuppressed patients: diagnosis and management.

PMID- 4353948
TI  - Histocompatibility antigens of human plasma. Localization to the HLD-3
      lipoprotein fraction.

PMID- 4353949
TI  - Transduction by bacteriophage MU-1.

PMID- 4353950
TI  - Polyoma gene function required for viral DNA synthesis.

PMID- 4353951
TI  - Testing by the "paired-label" antibody binding technique for feline leukemia
      virus-induced cell surface antigens (FeLV-CSA) on the surface of human
      rhabdomyosarcoma cells releasing RD-114 virus.

PMID- 4353952
TI  - Murine mammary tumor cell clones with varying degrees of virus expression.

PMID- 4353953
TI  - Effect of 2-deoxy-D-glucose on cell fusion induced by Newcastle disease and
      herpes simplex viruses.

PMID- 4353954
TI  - Structural components of Sendai virus. Serological and physicochemical
      characterization of hemagglutinin subunit associated with neuraminidase activity.

PMID- 4353955
TI  - Studies on herpes simplex virus DNA: denaturation properties.

PMID- 4353957
TI  - Synthesis of Epstein-Barr virus antigens and DNA in activated Burkitt somatic
      cell hybrids.

PMID- 4353956
TI  - Malignant transformation of hamster embryo fibroblasts following exposure to
      ultraviolet-irradiated human cytomegalovirus.

PMID- 4353958
TI  - Fine structural alterations with age in the fat body of the adult male housefly,
      Musca domestica.

PMID- 4353959
TI  - Quantitative microscopical studies of the mouse peritoneal macrophage following
      stimulation in vivo.

PMID- 4353960
TI  - The development of synapses in vitro between previously dissociated chick spinal
      cord neurons.

PMID- 4353961
TI  - [The innervation of the lophophore in a chilostome. Electra pilosa (L.)].

PMID- 4353962
TI  - Ultrastructural localization of glycogen in erythrocytes and developing
      erythrocytic cells in normal human bone marrow.

PMID- 4353963
TI  - Fine structure of the adenohypophysis in immature sockeye salmon, Oncorhynchus
      nerka.

PMID- 4353964
TI  - Ultrastructure of the pseudohermaphrodite rat testis.

PMID- 4353965
TI  - An analysis of some aspects of synaptosomal ultrastructure by the use of serial
      sections.

PMID- 4353966
TI  - Observations on skin structure and sloughing in the stone fish Synanceja
      verrucosa and related fish species as a functional adaptation to their mode of
      life.

PMID- 4353967
TI  - [Alveolar-cell carcinoma. 1. Classification, clinical data and macromorphology].

PMID- 4353968
TI  - [Current status of general antibiotic therapy].

PMID- 4353969
TI  - Small-sized haemagglutinin of vesicular stomatitis virus released spontaneously
      and with Nonidet P 40.

PMID- 4353970
TI  - Typing of Herpesvirus hominis strains by indirect immunofluorescence and
      biological markers.

PMID- 4353971
TI  - Spin changes in hemoproteins.

PMID- 4353972
TI  - Granular cell myoblastoma of multicentric origin involving the vulva: a case
      report.

PMID- 4353974
TI  - Evolving behavior in the clinical and experimental amphetamine (model) psychosis.

PMID- 4353973
TI  - The Chediak-Higashi syndrome. Fine structure of giant inclusions in freeze
      fractured neutrophils.
AB  - The technic of freeze-fracture and etching has been used in the present study to
      examine the fine structure of giant inclusions in circulating leukocytes from a
      patient with the Chediak-Higashi syndrome (CHS). The surface granularity of the
      membranes enclosing the giant inclusions differed slightly from that of normal
      sized organelles. Two types of giant granules were distinguished in replicas of
      freeze-fractured CHS neutrophils. The difference in fine structure suggests that
      one variety is a massively enlarged, but essentially unaltered primary lysosome,
      while the other develops as a result of continued fusion of small organelles with
      huge inclusions throughout the stages of polymorphonuclear leukocyte maturation.

PMID- 4353975
TI  - The dream-protein hypothesis.

PMID- 4353976
TI  - Alterations of liver metabolism associated with experimental acute pancreatitis.

PMID- 4353977
TI  - Diarrheogenic tumor of the pancreas.

PMID- 4353978
TI  - [Serology of treponemal infections among the Lobi of the Ivory Coast].

PMID- 4353979
TI  - Nonbacterial pneumonitis with antineoplastic therapy.

PMID- 4353981
TI  - Enuresis.

PMID- 4353982
TI  - Active, water-insoluble derivatives of D-glucose oxidase and alginic acid,
      chitin, and Celite.

PMID- 4353983
TI  - Automated primary screening for hyperlipoproteinemias.

PMID- 4353980
TI  - Etiology of breast cancer. II. Epidemiologic aspects.
AB  - The epidemiology of breast cancer is reviewed with particular emphasis on its
      etiology. A number of studies suggest that differences in breast cancer incidence
      are associated with differences in marital status, number of pregnancies, age at
      menarche, age at menopause, height and weight, socioeconomic status, geographic
      location and residence. However, in no case is the evidence adequate to establish
      a "cause and effect" relationship. The genetic component of these associations
      may be of primary importance, while other conditions such as marital status are
      probably indirect reflections of the operation of more fundamental factors.There
      is a general consensus that endocrine factors play an important part in mammary
      cancer occurrence. At present, the association between breast cancer and the
      presence of the virus-like (type B) particles in human milk is not established.

PMID- 4353984
TI  - Measurement of urinary aldosterone by a simplified radioimmunoassay procedure.

PMID- 4353985
TI  - The effects of hemicholinium-3 in an insect neuromuscular preparation.

PMID- 4353986
TI  - Action of imipramine on a serotonergic synapse.

PMID- 4353988
TI  - Glycogenolysis and lipolysis in Gallus domesticus during the perinatal period.

PMID- 4353989
TI  - Pituitary-adrenal axis activation as a function of hypothalamic 5
      hydroxytryptamine titre.

PMID- 4353987
TI  - Acetylcholine receptors and the diphasic action of nicotine in the American
      cockroach, Periplaneta americana (L.).

PMID- 4353990
TI  - Neuromuscular block in insects caused by the venom of the digger wasp Philanthus
      triangulum F.

PMID- 4353991
TI  - Transmitter substances in insects: a review.

PMID- 4353993
TI  - High resolution deuterium magnetic resonance: an approach to the study of
      molecular organization in biological membranes and model systems.

PMID- 4353992
TI  - Anaerobic cilio-excitation and metabolic stimulation by 5-hydroxytryptamine in
      bivalve gill.

PMID- 4353994
TI  - Activation by glucose of adenyl cyclase in pancreatic islets of the rat.

PMID- 4353995
TI  - Intracranial tumors in India: incidence and variations.

PMID- 4353996
TI  - Incidence and behavior pattern of intracranial tumors in Ceylon.

PMID- 4353997
TI  - Nerve sheath tumors.

PMID- 4353998
TI  - Demonstration of iodide transport defect but normal iodide organification in
      nonfunctioning nodules of human thyroid glands.
AB  - Benign and malignant nodules in human thyroid glands, which did not concentrate
      iodide in vivo, were also unable to accumulate iodide in vitro. The mean thyroid
      to-medium ratio (T/M) in seven benign nodules was 0.8+/-0.2 compared with 7+/-2
      in adjacent normal thyroid tissue. In four malignant thyroid nodules, the mean
      T/M was 0.5+/-0.1 compared with 11+/-4 in adjacent normal thyroid. Despite the
      inability of such nodules to concentrate iodide, iodide organification was
      present but was only one-half to one-third as active as in surrounding normal
      thyroid. Thyroid-stimulating hormone (TSH) increased iodide organification
      equally in both benign nodules and normal thyroid although it had no effect in
      three of the four malignant lesions. The reduction in organification is probably
      related to the absence of iodide transport, since incubation of normal thyroid
      slices with perchlorate caused similar diminution in iodide incorporation but no
      change in the response to TSH. Monoiodotyrosine (MIT) and di-iodotyrosine (DIT)
      accounted for most of the organic iodide in both the nodules and normal tissue.
      The MIT/DIT ratio was similar in normal and nodule tissue. The normal tissue
      contained much more inorganic iodide than the nodules, consistent with the
      absence of the iodide trap in the latter tissue. The thyroxine content of normal
      thyroid was 149+/-17 mug/g wet wt and 18+/-4 mug/g wet wt in the nodules. The
      transport defect in the nodules was not associated with any reduction in total,
      Na(+)-K(+)- or Mg(++)-activated ATPase activities or the concentration of ATP.
      Basal adenylate cyclase was higher in nodules than normal tissue. Although there
      was no difference between benign and malignant nodules, the response of adenylate
      cyclase to TSH was greater in the benign lesions. These studies demonstrate that
      nonfunctioning thyroid nodules, both benign and malignant, have a specific defect
      in iodide transport that accounts for their failure to accumulate radioactive
      iodide in vivo. In benign nodules, iodide organification was increased by TSH
      while no such effect was found in three of four malignant lesions, suggesting
      additional biochemical defects in thyroid carcinomas.

PMID- 4354001
TI  - AY-9944 inhibition of sterol biosynthesis in Chlorella emersonii.

PMID- 4354000
TI  - Collagen-mediated platelet aggregation. Effects of collagen modification
      involving the protein and carbohydrate moieties.
AB  - In an effort to elucidate the nature of the collagen-platelet interaction, the
      effects of collagen modification on platelet aggregation have been studied. We
      have shown that purified rat skin (salt) soluble collagen is effective at about
      20 nM in mediating platelet aggregation in human platelet-rich plasma. This
      concentration is somewhat greater than that required of several skin insoluble
      collagens (ca. 10 nM). Both the alpha1(I) and alpha2 chains from rat skin soluble
      collagen produced platelet aggregation, but only at concentrations of about 13
      muM and 55 muM, respectively. In contrast, heat-denatured collagen and chains
      (e.g., 65 muM alpha1(I) and 160 muM alpha2) failed to induce platelet aggregation
      and to inhibit platelet aggregation by native collagen. Glycopeptides were
      prepared from human skin insoluble collagen by extended digestion with bacterial
      collagenase and trypsin, and were purified by gel filtration into two classes.
      One class of higher molecular weight contained sialic acid, glucosamine,
      galactosamine, fucose, mannose, galactose, and glucose, and the other of lower
      molecular weight consisted primarily of a mixture of galactose and galactosyl
      glucose units O-glycosidically linked to hydroxylysine-containing peptides. We
      found that, after the residual tryptic activity contaminating the higher
      molecular weight fraction was inhibited, neither of the glycopeptide classes
      produced nor inhibited native human skin insoluble collagen-mediated platelet
      aggregation at the highest concentration examined (ca. 1-2 mg glycopeptide per ml
      of platelet-rich plasma). Highly purified samples of the hydroxylysyl glycosides,
      hydroxylysylgalactose and hydroxylysylgalactosylglucose (Hyl-Gal and Hyl-Gal-Glc,
      respectively), were prepared from human urine and labeled at galactose using
      galactose oxidase followed by reduction with tritiated borohydride. Binding
      studies with platelet-rich plasma showed that, at concentrations greater than 50
      nM, Hyl-Gal gives apparent binding to platelets, but there was no evidence of Hyl
      Gal-Glc binding to platelets at concentrations up to 250 nM. At concentrations
      several hundredfold higher than the equivalents present in the minimum
      concentration of rat skin soluble collagen required for platelet aggregation,
      neither Hyl-Gal (at 29 muM) nor Hyl-Gal-Glc (at 18 muM) caused platelet
      aggregation or inhibited platelet aggregation by native collagen. Also, at a
      concentration of 85 muM (which represents a concentration about two thousandfold
      higher than the equivalents in the minimum concentration of soluble collagen
      required for platelet aggregation) the Gal-Glc-containing 36 residue rat skin
      soluble collagen alpha1(I)cyanogen bromide #5 peptide had no platelet aggregating
      or inhibiting activity. Modification of at least 90% of the rat skin soluble
      collagen carbohydrate by mild periodate oxidation had no effect on the platelet
      aggregating activity. Human skin insoluble collagen was reacted with periodate
      under the same conditions, and this had no demonstrable effect on its ability to
      induce platelet aggregation. This indicates that the normal carbohydrate side
      chains of these collagens are not required for the platelet interaction that
      produces the release of ADP and other metabolic constituents and leads to
      aggregation.Thus, collagen-platelet interactions appear to involve at least two
      distinct binding sites on the platelet plasma membrane. One is a protein binding
      site that activates platelet aggregation and has high specificity and affinity
      for the collagen triple-helical fold or perhaps even for a particular amino acid
      sequence in the triple helix.

PMID- 4353999
TI  - The kinetics of intramolecular distribution of 15N in uric acid after
      administration of (15N) glycine. A reappraisal of the significance of
      preferential labeling of N-(3+9) of uric acid in primary gout.
AB  - THE CONCEPT OF AN ABNORMALITY OF GLUTAMINE METABOLISM IN PRIMARY GOUT WAS FIRST
      PROPOSED ON THE BASIS OF ISOTOPE DATA: when [(15)N]glycine was administered to
      gouty subjects, there was disproportionately great enrichment of N-(3 + 9) of
      uric acid, which derive from the amide-N of glutamine. An unduly high
      concentration of (15)N in glutamine was postulated, and attributed to a
      hypothetical defect in catabolism of glutamine. Excess glutamine was proposed as
      the driving force of uric acid overproduction. WE HAVE REEXAMINED THIS
      PROPOSITION IN FOUR GOUTY SUBJECTS: one mild overproducer of uric acid with
      "idiopathic gout," one marked overproducer with high-grade but "partial"
      hypoxanthine-guanine phosphoribosyl-transferase deficiency, and two extraordinary
      overproducers with superactive phosphoribosylpyrophosphate synthetases. In the
      last three, the driving force of excessive purine biosynthesis is a known surplus
      of alpha-5-phosphoribosyl-1-pyrophosphate. Disproportionately high labeling of N
      (3 + 9) was present in all four gouty subjects, most marked in the most
      flamboyant overproducers. The precursor glucine pool was sampled by periodic
      administration of benzoic acid and isolation of urinary hippuric acid. Similarly,
      the precursor glutamine pool was sampled by periodic administration of
      phenylacetic acid and isolation of the amide-N of urinary phenylacetylglutamine.
      The time course of (15)N enrichment of hippurate differed from that of the amide
      N of glutamine. Whereas initial enrichment values of hippurate were very high,
      those of glutamine-amide-N were low, increasing to a maximum at about 3 h, and
      then declining less rapidly than those of hippurate. However, enrichment values
      of hippurate and of phenacetyl glutamine were normal in all of the gouty subjects
      studied. Thus, preferential enrichment of N-(3 + 9) in gouty overproducers given
      [(15)N]glycine does not necessarily reflect a specific abnormality of glutamine
      metabolism, but rather appears to be a kinetic phenomenon associated with
      accelerated purine biosynthesis per se.In addition, greater enrichment of N-9
      than of N-3 on days 1 and 2 provided suggestive evidence for a second pathway for
      synthesis of the initial precursor of purine biosynthesis, phosphoribosylamine,
      perhaps utilizing ammonia rather than the amide-N of glutamine as nitrogen donor.
      In this limited study, the activity of this potential second pathway did not
      appear to be selectively increased in gout.

PMID- 4354002
TI  - Search for prostaglandin A1 in onion.

PMID- 4354003
TI  - The effect of adenosine and adenine nucleotides on the cyclic adenosine 3', 5'
      phosphate content of guinea pig cerebral cortex slices.

PMID- 4354005
TI  - A kinetic model of a cyclic system for the fluorometric microdetermination of
      adenosine triphosphatase activity.

PMID- 4354004
TI  - Analogues of adenosine 3',-5'-cyclic phosphate as activators of phosphorylase b
      kinase and as substrates for cyclic 3',5'-nucleotide phosphodiesterase.

PMID- 4354006
TI  - Study of the mechanism of renal vacuologenesis induced in the rat by
      ethylenediaminetetraacetate. Comparison of the cellular activities of calcium and
      chromium chelates.

PMID- 4354007
TI  - Adverse effect of cytosine arabinoside on disseminated zoster in a controlled
      trial.

PMID- 4354008
TI  - Stimulation of yeast RNA synthesis by cycloheximide and 3',5'-cyclic AMP.

PMID- 4354009
TI  - ATP requirement for release of adenovirus mRNA from isolated nuclei.

PMID- 4354010
TI  - Alkaline phosphatase in vascular smooth muscle.

PMID- 4354011
TI  - Angiotensin receptors in smooth muscle cell membranes.

PMID- 4354012
TI  - Plasma membrane proteins of normal and Rous sarcoma virus-transformed chick
      embryo fibroblasts.

PMID- 4354014
TI  - Antisynaptosome antibodies affect synaptosomal permeability to neurotransmitters.

PMID- 4354013
TI  - Stimulation of calcitonin release in vitro by purine and pyrimidine nucleotides.

PMID- 4354016
TI  - Long-term results of breast cancer treatment during 1959-1966.

PMID- 4354017
TI  - REM sleep deprivation impairs latent extinction in rats.

PMID- 4354015
TI  - Modification of expression of the testicular feminization (Tfm) gene of the mouse
      by a "controlling element" gene.

PMID- 4354018
TI  - The brain scan.

PMID- 4354019
TI  - Serum levels of parathyroid hormone in the Zollinger-Ellison syndrome.

PMID- 4354021
TI  - Effects of adenosine-3',5'-monophosphate and 5-hydroxytryptamine on the secretory
      activity of the canine testis.

PMID- 4354020
TI  - On the development of insulin sensitivity by mouse mammary gland in vitro.

PMID- 4354022
TI  - Suppurative perichondritis of the auricle.

PMID- 4354023
TI  - Management of nasopharyngeal angiofibroma.

PMID- 4354024
TI  - Quantitative differential thermal analysis of small dust samples containing
      quartz.

PMID- 4354025
TI  - Bureau of Mines procedure for analysis of respirable dust from coal mines.

PMID- 4354026
TI  - A monumental study--reconstruction of a 1920 granite shed.

PMID- 4354027
TI  - [Elimination of sigma virus, by temperature or by ethylmethane-sulfonate feeding,
      from the germ cells of female Drosophila melanogaster flies stabilized for the
      virus].

PMID- 4354028
TI  - Isolation of polypeptides containing the intermolecular cross-link  , '
      dihydroxylysinonorleucine from dentin collagen.

PMID- 4354029
TI  - Respiratory activation of 2,4-dinitrophenol-stimulated ATPase activity in plant
      mitochondria.

PMID- 4354031
TI  - Interconversion of the A and B forms of ceramide trihexosidase from human plasma.

PMID- 4354030
TI  - Energy dependent changes in the cytochromes of the mitochondrial respiratory
      chain.

PMID- 4354033
TI  - Gadolinium asa probe of the alkaline earth and ATP-metal binding sites in
      pyruvate kinase.

PMID- 4354032
TI  - Nucleoside diphosphatase from pig liver: purification and some properties.

PMID- 4354034
TI  - Incorporation of glucosamine into rhodopsin in isolated bovine retina.

PMID- 4354035
TI  - Superoxide dismutase: a comparison of rate constants.

PMID- 4354039
TI  - Radiation therapy for cancer of the lung: previous experience and definition of
      current issues.

PMID- 4354036
TI  - Immunological studies on glucose 6-phosphate dehydrogenase of rat liver.

PMID- 4354040
TI  - A clinical trial of cyclophosphamide (NSC-26271) and radiation therapy for oat
      cell carcinoma of the lung.

PMID- 4354041
TI  - Combination chemotherapy and radiation therapy for small cell carcinoma of the
      lung.

PMID- 4354042
TI  - Should initial treatment of small cell carcinoma include systemic chemotherapy
      and brain irradiation?

PMID- 4354044
TI  - A follow-up survey of out-patients in a medical clinic for Africans at Harare
      Hospital in Rhodesia.

PMID- 4354043
TI  - Observer variability and reliability in lung cancer diagnosis.

PMID- 4354045
TI  - Arousing effects of trophic hormones in hibernating Citellus lateralis.

PMID- 4354046
TI  - Behr's syndrome: familial optic atrophy, spastic diplegia and ataxia.

PMID- 4354047
TI  - The problem of the Lennox syndrome.

PMID- 4354048
TI  - [Spectroscopic study on folic acid. Demonstration of intramolecular effects].

PMID- 4354049
TI  - Stimulation of ribonucleic-acid synthesis in chick-embryo fibroblasts by
      exogenous adenosine 3':5'-monophosphate.

PMID- 4354050
TI  - Microbial transformation of cholesterol into coprostanol. Properties of a 3-oxo-
      4-steroid-5 beta-reductase.

PMID- 4354051
TI  - Effect of pH on electron-paramagnetic-resonance spectra of ceruloplasmin.

PMID- 4354052
TI  - [Cyclopeptin and dehydrocyclopeptin. Intermediates in the biosynthesis of
      cyclopeptin-viridicatin alkaloids in Penicillium cyclopium Westling].

PMID- 4354054
TI  - Electron spin resonance spectra of white, cardiac and various red skeletal
      muscles of the carp, Cyprinus carpio L.

PMID- 4354053
TI  - Effect of Bordetella pertussis vaccine on plasma corticosterone level and on ACTH
      induced corticosterone secretion in rats.

PMID- 4354055
TI  - Shortened duration of drug-induced behavioral excitation in rats with septal
      lesions.

PMID- 4354056
TI  - Effect of prostaglandins on cyclic AMP concentrations in toad bladder and rat
      kidney.

PMID- 4354057
TI  - Reaction of rabbit muscle apo-glyceraldehyde-3-P-dehydrogenase with pyridoxal-5'
      phosphate.

PMID- 4354058
TI  - The binding of divalent cations by purified gangliosides.

PMID- 4354059
TI  - Steroid metabolism in testis tissue. Concentrations of testosterone, pregnenolone
      and 5 -androst-16-en-3 -ol in normal and cryptorchid rat testis, and in isolated
      interstitial and tubular tissue.

PMID- 4354060
TI  - The characterization of glycolipids derived from long-chain polyprenols: chemical
      synthesis of  -D-mannopyranosyl dolichyl phosphate.

PMID- 4354062
TI  - On the specificity of cyclic AMP action in Escherichia coli.

PMID- 4354061
TI  - The unambiguous characterization of dolichol phosphate mannose as a product of
      mannosyl transferase in pig liver endoplasmic reticulum.

PMID- 4354063
TI  - Correlation between (3H)dexamethasone binding to a rat liver cytosol receptor
      protein and stimulation of RNA synthesis by glucocorticosteroids.

PMID- 4354064
TI  - Cholesterol and phospholipid composition of mitochondria and microsomes isolated
      from morris hepatoma 5123 and rat liver.

PMID- 4354065
TI  - Stimulation of RNA synthesis in Cicer arietinum seedlings by cyclic 3':5'
      adenosine monophosphate.

PMID- 4354066
TI  - [Morphologic and histochemical studies of vaginal lining epithelium in women in
      term pregnancy].

PMID- 4354067
TI  - [Pattern of some phosphatases and aminopeptidases in tissues of adenocarcinoma of
      the uterus].

PMID- 4354068
TI  - Ganglioside patterns and phenotypic characteristics in a normal variant and a
      transformed back variant of a simian virus 40-induced hamster tumor cell line.
AB  - Ganglioside patterns of a cloned Simian virus 40- (SV40) induced hamster tumor
      cell (Cl(2)TSV(5)-S), its normal variant (Cl(2)TSV(5)-R) which are Cl(2)TSV(5)-S
      gradually adapted to grow in the presence of 2 microg/ml actinomycin D and
      exhibit certain normal phenotypic characteristics, and its back variant
      (Cl(2)TSV(5)-RR), which are Cl(2)TSV(5)-R cells grown in the absence of
      actinomycin D for more than 60 passages and which exhibit greater phenotypic
      similarity to Cl(2)TSV(5)-S cells, have been analyzed. All three cell lines
      contain N(acetylneuraminyl) galactosylglycosyl ceramide (hematoside, GM(3)), N
      acetylgalactosaminyl (N-acetylneuraminyl) galactosylglucosyl ceramide (GM(2)),
      and a higher ganglioside tentatively identified as disialohematoside. However,
      Cl(2)TSV(5)-R have more GM(2) than Cl(2)TSV(5)-S whereas Cl(2)TSV(5)-RR contain
      an intermediate amount of GM(2). The amount of GM(2) is correlative with the
      activity of UDP-N-acetylgalactosamine: hematoside N-acetylgalactosaminyl
      transferase in the extract of the three cell lines and with their agglutination
      by wheat germ agglutinin.

PMID- 4354069
TI  - Cell cycle-dependent changes in the surface membrane as detected with
      (3H)concanavalin A.

PMID- 4354070
TI  - The effect of environmental pH on the growth of normal and malignant cells.

PMID- 4354071
TI  - Cell division, ciliary regeneration and cyclic AMP in a unicellular system.

PMID- 4354072
TI  - Isolation and characterization of revertant cell lines. II. Growth control of a
      polyploid revertant line derived from SV40-transformed 3T3 mouse cells.

PMID- 4354073
TI  - Post-transcriptional regulation of catalase synthesis in rat liver and hepatoma:
      factors activating and inhibiting catalase synthesis.

PMID- 4354074
TI  - Post-transcriptional regulation of catalase synthesis in rat liver and hepatoma:
      binding of inhibiting factor(s) with polyribosomes synthesizing catalase.

PMID- 4354075
TI  - Defective cyclic adenosine-3', 5'-phosphate-phosphodiesterase regulation in
      morphogenetic mutants of Dictyostelium discoideum.

PMID- 4354076
TI  - Synthesis of polyoma proteins in vitro.

PMID- 4354077
TI  - Length measurements of RNA synthesized in vitro by Escherichia coli RNA
      polymerase.

PMID- 4354079
TI  - [Pattern of recruitment of phrenic motor neurons].

PMID- 4354078
TI  - SV40 DNA: quantitative conversion of closed circular to open circular form by an
      ethidium bromide-restricted endonuclease.

PMID- 4354080
TI  - Clostridium infection after intra-amniotic hypertonic saline injection for
      induced abortion.

PMID- 4354081
TI  - Australia antigen in liver tissue--an immunofluorescent and immunoelectron
      microscopic study.

PMID- 4354082
TI  - Effect of myoinositol and other polyols on  -galactosidase of mammarian tissues.

PMID- 4354083
TI  - [Changes of the renin-angiotensin system in fasting rats].

PMID- 4354084
TI  - Primary herpetic gingivostomatitis of adult onset. Clinical, laboratory, and
      ultrastructure correlations identifying viral etiology.

PMID- 4354085
TI  - Effects of PGF2  infusion on human cortisol biosynthesis.

PMID- 4354086
TI  - Effects of thyrotropin and N6,02'-dibutyryl cyclic 3'.5'-adenosine monophosphate
      on prostaglandin levels in thyroid.

PMID- 4354087
TI  - Antagonism of prostaglandin-promoted pituitary cyclic AMP accumulation and growth
      hormone secretion in vitro by 7-oxa-13-prostynoic acid.

PMID- 4354088
TI  - Prostaglandin release by the isolated perfused rabbit heart.

PMID- 4354090
TI  - Renomedullary interstitial cells (RIC), prostaglandins (PG) and the
      antihypertensive function of the kidney.

PMID- 4354089
TI  - The effect of PGE1 on ADP-induced aggregation in refractory platelets.

PMID- 4354091
TI  - Differential inhibition by prostaglandins of the renal actions of pressor
      stimuli.

PMID- 4354092
TI  - Significance of the effects of prostaglandins on renal and adrenal function in
      man.

PMID- 4354093
TI  - An essay: prostaglandins and toxemia of pregnancy.

PMID- 4354094
TI  - Inotropic effects of prostaglandins, fatty acids and adenosine phosphates on
      hypodynamic frog hearts.

PMID- 4354095
TI  - [Influence of analogs of cyclic AMP on serum insulin concentration in rats].

PMID- 4354096
TI  - [Aspects of the role of cyclic AMP in the nervous system].

PMID- 4354098
TI  - [Psychotropic drugs and neurotransmitter substances].

PMID- 4354097
TI  - [Monoamines and corticotropin secretion].

PMID- 4354099
TI  - Further studies on the antigenicity of some injectable tissue extracts.

PMID- 4354100
TI  - [Protective action of polyinosinic-polycytidylic acid in viral and transplanted
      leukemia in mice].

PMID- 4354101
TI  - [Report of 2 cases of hemolytic microangiopathic anemia associated with mucin
      producing adenocarcinoma of the stomach].

PMID- 4354102
TI  - [Correlation between the histopathology and natural history of intestinal
      adenocarcinoma and diffuse undifferentiated carcinoma of the stomach].

PMID- 4354103
TI  - [Enzyme histochemical studies on metabolism of steroids and steroid conjugates in
      the juxtamedullary X-zone of the mouse].

PMID- 4354104
TI  - Evaluation of the effectiveness of treatment on adult height prognosis in
      disorders with advanced and retarded bone age. Height and height velocity related
      to chronological or to bone age.

PMID- 4354105
TI  - Improvement of adult height prognosis in precocious puberty by cyproterone
      acetate.

PMID- 4354106
TI  - Uptake and degradation of 3H-phenoxymethylpenicillin in rat liver slices.

PMID- 4354107
TI  - Cyclic AMP as a mediator of the relaxing action of papaverine, nitroglycerine,
      diazoxide and hydralazine in intestinal and vascular smooth muscle.

PMID- 4354108
TI  - The effect of guanethidine pretreatment on transmission in the superior cervical
      ganglion.

PMID- 4354109
TI  - Pox in wild birds.

PMID- 4354110
TI  - Abnormal biochemistry in myocardial failure.

PMID- 4354111
TI  - Toxemia of pregnancy. Mechanism and therapeutic management.

PMID- 4354112
TI  - An assessment of "free" and conjugated estriol in uncomplicated and complicated
      pregnancy plasma.

PMID- 4354113
TI  - Trophoblastic disease in Uganda.

PMID- 4354115
TI  - Clinical and metabolic features of anorexia nervosa.

PMID- 4354114
TI  - Primary amenorrhea: a simplified approach to diagnosis.

PMID- 4354117
TI  - Exercise of normal muscle: biochemical effects.

PMID- 4354116
TI  - Carcinoma of the extrahepatic biliary tract.

PMID- 4354118
TI  - Complementation of theta-toxinogenicity between mutants of two groups of
      Clostridium perfringens.

PMID- 4354119
TI  - Fluorescence studies on polyoma virus.

PMID- 4354120
TI  - A "spot-infection technique" for titration and neutralization of poliovirus.

PMID- 4354121
TI  - Serial propagation of varicella virus in primary rabbit kidney cells.

PMID- 4354122
TI  - Influence of fasting and hemin on microsomal cytochromes and enzymes.

PMID- 4354123
TI  - Interaction of cytochrome c with lipid monolayers.

PMID- 4354124
TI  - Characterisation of the surface of bovine milk fat globule membrane using
      microelectrophoresis.

PMID- 4354125
TI  - The isolation and characterization of plasma membrane from cultured cells. V. The
      chemical composition of plasma membranes isolated from chicken tumors initiated
      with virus-transformed cells.

PMID- 4354126
TI  - Isolation of plasma membranes from Ehrlich ascites tumor cells. Influence of
      amino acids on (Na++K+)-ATPase and K+-stimulated phosphatase.

PMID- 4354127
TI  - Binding of proteins to mycoplasma membranes.

PMID- 4354128
TI  - Mobility of spin-labelled sulfhydryl sites in excitable tissue.

PMID- 4354129
TI  - Preparation of inverted plasma membrane vesicles from isolated adipocytes.

PMID- 4354130
TI  - Spin labels as enzyme substrates. Heterogeneous lipid distribution in liver
      microsomal membranes.

PMID- 4354131
TI  - The effects of long-chain alcohols on membrane lipids and the (Na++K+)-ATPase.

PMID- 4354133
TI  - The purification of membrane-associated tumour antigens by preparative
      polyacrylamide gel electrophoresis.

PMID- 4354132
TI  - Deoxycytidine uptake by isolated membrane vesicles from Escherichia coli K 12.

PMID- 4354135
TI  - Effect of guanosine 3':5'-monophosphate on the hydroosmotic activity of adenosine
      3':5'-monophosphate in toad urinary bladder.

PMID- 4354134
TI  - Dibutyryl cyclic adenosine monophosphate enhancement of alpha-methyl-D-glucoside
      accumulation by kidney cortex slices.

PMID- 4354136
TI  - Alveolar adenocarcinoma complicating pulmonary fibrosis due to mitral stenosis.

PMID- 4354137
TI  - Inhibition by lithium of prostaglandin E1 and norepinephrine effects on cyclic
      adenosine monophosphate production in human platelets.

PMID- 4354139
TI  - Factors affecting proton magnetic resonance linewidths of water in several rat
      tissues.

PMID- 4354138
TI  - Urinary corticosteriod and diphenylhydantoin metabolite patterns in neonates
      exposed to anticonvulsant drugs in utero.

PMID- 4354140
TI  - The control of phosphorylase kinase phosphatase by "second site phosphorylation";
      a new form of enzyme regulation.

PMID- 4354142
TI  - Correlation of substrate specificity of cAMP-phosphodiesterase in Dictyostelium
      discoideum with chemotactic activity of cAMP-analogues.

PMID- 4354141
TI  - Isolation of acidic lipoproteins from brain chromatin. Their relation to the
      acidic nonhistone proteins.

PMID- 4354143
TI  - Stimulation by prostaglandin E1 of adenosine 3':5'-cyclic monophosphate formation
      in neuroblastoma cells in the presence of phosphodiesterase inhibitors.

PMID- 4354144
TI  - [In vitro perfusion of the human utero-tubo-ovarian unit. 1. Evaluation of
      experimental conditions and the studies of the early stage of preganacy and
      trophoblastic neoplasia].

PMID- 4354145
TI  - Studies of carcinoembryonic antigen activity of whole and extracted serum in
      ulcerative colitis.
AB  - The present study has used a microradioimmunoassay to detect carcinoembryonic
      antigen(s) (CEA) in whole and extracted serum in 77 patients with ulcerative
      colitis, two of whom had coexisting colonic carcinoma, and 69 patients with
      carcinoma of the colon or rectum. Taking 5 ng/ml as the level of positivity, the
      CEA assay on whole serum showed positive results in patients with ;active'
      ulcerative colitis (15 of 17) but not in those with ;inactive' disease (0 of 23).
      In two patients, levels fell during drug-induced remission. Our results also
      indicated that a positive result for CEA on extracted serum was associated with
      carcinomatous changes in ulcerative colitis in contrast to uncomplicated
      ulcerative colitis in which positive results were obtained only with whole serum.

PMID- 4354147
TI  - Studies on the mechanism of the priming effect of interferon on interferon
      production by cell cultures exposed to poly(rI)-poly(rC).
AB  - Interferon induction by poly(rI).poly(rC) in primary rabbit kidney and mouse L
      929 cell cultures was markedly increased if the cells were previously treated
      with homologous interferon. This priming effect has been established with
      different times of exposure of the cells to poly(rI).poly(rC), and was most
      pronounced for short pulses of contact of the polynucleotide with the cells (10
      s, 1 min). Treatment of the cells with pancreatic ribonuclease immediately after
      their exposure to poly(rI).poly(rC) brought about a relatively greater reduction
      of the interferon response in interferon-primed cells than it did in unprimed
      cell cultures. Priming of the cells with interferon did not increase cell-binding
      of poly(rI).poly(rC), whether this cell-binding was measured quantitatively (by
      radioactivity, upon exposure of the cells to radiolabeled polymer) or
      qualitatively (by antiviral activity, by assaying the cell extract for virus
      plaque reduction). Similarly, interferon priming did not alter the sensitivity of
      cell-associated poly(rI).poly(rC) to extraneous ribonuclease treatment. Finally,
      priming with interferon did not decrease the rate of degradation of cell-bound
      poly(rI).poly(rC) by cellular nucleases nor did it increase the anti-nuclease
      potency of the cells. The exact mechanism by which previous exposure of the cells
      to interferon enhances subsequent interferon production, induced by either
      synthetic polynucleotides or viruses, has not yet been resolved.

PMID- 4354146
TI  - Hypersecretion of zymogen granules in the pathogenesis of cystic fibrosis.
AB  - In the submandibular saliva of 10 cystic fibrosis subjects and 10 controls the
      turbidity and elevated calcium, protein, and amylase concentrations of the cystic
      fibrosis secretions, and precipitation of calcium and phosphate in a ratio
      consistent with hydroxyapatite have been confirmed. By electron microscopy the
      centrifuged deposits of the cystic fibrosis saliva were seen to be composed
      predominantly of round or oval subcellular corpuscles. By comparison with
      submandibular gland, these corpuscles have been identified as inclusion bodies
      (spherules) from within zymogen granules. Hydroxyapatite crystals formed on
      standing in the cystic fibrosis saliva. Polyacrylamide gel disc electrophoresis
      of the cystic fibrosis centrifuged deposits showed five bands, one of which, band
      4, was more prominent in the deposit than in the supernatant gels. Comparisons
      have been made between these results and other studies and have shown (1)
      elevated calcium and protein in cystic fibrosis exocrine secretions; (2)
      simultaneous secretion of calcium and enzymes from salivary glands, stomach, and
      pancreas; and (3) increased salivary secretion of calcium and protein in response
      to parasympathomimetic and sympathomimetic drugs. Hypersecretion of calcium
      containing zymogen granules is postulated as the cause of obstruction in cystic
      fibrosis.

PMID- 4354148
TI  - Inhibition of enzymes by human salivary immunoglobulin A.
AB  - Human whole saliva inhibited bacterial neuraminidases and the inhibition was
      found to reside in the salivary IgA fraction. Further, salivary immunoglobulin
      (Ig)A inhibited various bacterial enzymes and toxins: neuraminidases from
      Streptococcus mitis, Streptococcus sanguis, and Clostridium perfringens,
      hyaluronidase and chondroitin sulfatase from oral bacteria, diphtheria toxin, and
      streptolysin O. The inhibitory activity of salivary IgA did not correlate with
      that of serum on the basis of minimum inhibitory dose. A small amount of salivary
      IgA was required to inhibit oral bacterial neuraminidases, whereas a large amount
      was required to inhibit other bacterial neuraminidase. Therefore, it is concluded
      that the absence of neuraminidase activity of oral bacteria in whole saliva may
      be due to specific inhibition by salivary IgA.

PMID- 4354149
TI  - Role of zinc in the production of Clostridium perfringens alpha toxin.
AB  - Clostridium perfringens was found to produce alpha toxin in a synthetic medium
      containing zinc; in medium containing no zinc, a little toxin was detected in the
      early logarithmic phase of growth and it disappeared rapidly. No intracellular
      accumulation of alpha toxin protein occurred whether or not zinc was present in
      the medium. In zinc-deficient medium, the organisms produced and released into
      the surrounding medium the protein specifically precipitable with alpha antitoxin
      in an amount comparable to that of alpha toxin produced in the zinc-containing
      medium. The protein combined rapidly in some unknown way with zinc to form the
      active and stable alpha toxin.

PMID- 4354150
TI  - Interferon responsiveness of rabbit synovial cells and chondrocytes.
AB  - Rabbit synovial cells (SC), articular chondrocytes (AC), and epiphyseal (EC)
      chondrocytes were grown in vitro. A portion of the spectrum of human pathogenic
      viruses infective for the cells was determined. Responses of the cells to
      different viruses or a chemical inducer of interferon varied, with EC responding
      vigorously and with high titers, AC responding only to chemical inducer and
      influenza virus, and SC producing no detectable interferon. All cells supported
      prolonged growth of influenza virus without showing microscopic cytopathology.

PMID- 4354152
TI  - Visna virus infection of sheep and human cells in vitro--an ultrastructural
      study.

PMID- 4354153
TI  - The effect of x-radiation on spermatogenesis and the fertility of Schistocerca
      gregaria (Forsk.).

PMID- 4354151
TI  - Ultrastructural characterization of genome of epizootic hemorrhagic disease
      virus.
AB  - Purified epizootic hemorrhagic disease (EHD) virus preparations were treated with
      urea and sodium perchlorate. The viral ribonucleic acid (RNA) released when
      spread on protein monolayers according to the Kleinschmidt technique was examined
      by rotary shadow-casting electron microscopy. The viral RNA released by urea
      treatment had filaments which frequently formed three to five loop-shaped figures
      of varied length. In 80% of the virus particles the lengths of the viral RNA
      released were 2.5 to 4.5 mum. The sodium perchlorate-released viral nucleic acid
      also appeared linear, and about 70% had lengths of 0.1 to 2.0 mum, the longest
      filament measuring 5.8 mum. Evidence was obtained that EHD virus contains double
      stranded RNA as its genetic material and the molecular weight of the EHD viral
      RNA was calculated to be 12.2 x to 10(6) to 15.1 x 10(6) daltons.

PMID- 4354154
TI  - Glycerolipid synthesis in rat adipose tissue. II. Properties and distribution of
      phosphatidate phosphatase.
AB  - The properties and subcellular distribution of phosphatidate phosphatase (EC
      3.1.3.4) from adipose tissue have been investigated. The enzyme was assayed using
      both aqueous phosphatidate and membrane-bound phosphatidate as substrates. When
      measured with aqueous substrate, activity was detected in the mitochondria, the
      microsomes, and the soluble fraction. Mg(2+) at low concentration stimulated the
      phosphatidate phosphatase from soluble and microsomal fractions but had no effect
      on the mitochondrial phosphatidate phosphatase. At higher concentration Mg(2+)
      was inhibitory. In the presence of Mg(2+), the phosphatidate phosphatase from
      soluble and microsomal fractions was active against membrane-bound phosphatidate.
      No activity was demonstrated with membrane-bound substrate in the absence of
      Mg(2+). Mitochondria did not contain activity toward the membrane-bound
      substrate. The rate of utilization of aqueous phosphatidate was always higher
      than that of membrane-bound substrate. These results indicate that there are at
      least two different phosphatidate phosphatases in adipose tissue.

PMID- 4354155
TI  - A regional survey of myelin development: some compositional and metabolic
      aspects.
AB  - A survey of differences in composition and metabolism of myelin from five areas
      of the central nervous system was made in brain and spinal cord slices of the rat
      from 20 days to 20 months postnatal age. Purified myelin from the forebrain areas
      showed a composition characteristic of immaturity longer than did myelin from the
      hindbrain and spinal cord. The trend of chemical maturity is in agreement with
      the anatomical observations that myelination begins in the hindbrain and proceeds
      rostrally. Myelin recovery per 100-mg slice increased continually from 20 days to
      20 months of age, while the uptake of [1-(14)C]acetate into myelin lipid and of
      [1-(14)C]leucine into myelin protein decreased precipitously with age. Taking
      into account the continuous increase in myelin during maturation, a calculation
      was made of the total amount of incorporation of labeled material into lipids or
      proteins per 100-mg slice for each region at each age. The metabolic
      characteristics of myelin from the cerebral cortex (including the corpus
      callosum), the thalamic area, and the cerebellum were very similar, while myelin
      from brainstem and spinal cord was metabolically more active, especially at the
      early ages. Synthesis of lipid in the myelin sheath represents about 50% of the
      lipid synthesis of the whole brain and about 75% of that of the spinal cord. The
      proportion of myelin-related protein synthesis is much less, probably less than
      10% of the protein synthesis occurring in whole brain and about 15% of that in
      the spinal cord except at early ages.

PMID- 4354156
TI  - Regulation by dietary choline of hepatic fatty acid synthetase in the rat.
AB  - Fatty acid synthetase activity was measured in the high-speed supernatant
      fraction of liver homogenates from rats fed a semisynthetic diet low in
      lipotropic factors. If choline was omitted from the diet, a significant increase
      of fatty acid synthetase activity was observed after two feedings of the
      deficient diet. Compared with controls, the increase of fatty acid synthetase
      activity was of a magnitude that could account for the amount of triglyceride
      accumulating in the hepatic floating lipid fraction. Gas-liquid chromatographic
      analysis of the floating lipid triglycerides showed an increased content of
      palmitic acid due to choline deficiency; this increase could be predicted from
      the increased fatty acid synthetase activity and its known characteristic yield
      of palmitic acid.

PMID- 4354157
TI  - A hypothesis relating lymphocyte phosphorylation and transport of ara-C
      (cytarabine) to its antiviral activity.

PMID- 4354158
TI  - Diffusion models for firing of a neuron with varying threshold.

PMID- 4354159
TI  - Contribution of the free energy of mixing of hydrophobic side chains to the
      stability of the tertiary structure of proteins.

PMID- 4354160
TI  - Clostridium welchii enterocolitis in arteriosclerotic patients.

PMID- 4354161
TI  - Application of radioimmunoassay to the renin-angiotensin system and to
      aldosterone.

PMID- 4354162
TI  - Peptide hormone binding to receptors: a review of direct studies in vitro.

PMID- 4354163
TI  - Measurement of steroid hormones using intracellular receptor proteins.

PMID- 4354164
TI  - Application of competitive ligand-binding radioassays to the nucleotides.

PMID- 4354165
TI  - The impact of radioimmunoassay on our understanding of human adrenal physiology.

PMID- 4354166
TI  - Radioimmunoassay methodology: application to problems of heterogeneity of peptide
      hormones.

PMID- 4354167
TI  - Measurements of renin-angiotensin-aldosterone.

PMID- 4354170
TI  - Gelatin: a poor substrate for a mammalian collegenase.
AB  - A rabbit tumor collagenase was purified more than 5000-fold. In this form it
      degrades native collagen in helical conformation at 37 degrees C, pH 7.6, into
      two fragments, but it had little capacity to cleave gelatin, an indication of the
      importance of higher-order structure of substrate for this enzyme in pure form.
      It is likely that, in vivo, enzymes other than collagenase degrade gelatin
      polypeptides produced by primary collagenolysis.

PMID- 4354169
TI  - Thyrotropin- and prostaglandin E2-responsive adenyl cyclase in thyroid plasma
      membranes.

PMID- 4354168
TI  - Role of the renal lymph in relation to the renin-angiotensin system in the rat.

PMID- 4354172
TI  - Gamma-aminobutyric acid antagonism in visual cortex: different effects on simple,
      complex, and hypercomplex neurons.
AB  - Intravenous bicuculline was used to examine how removing gamma-aminobutyric acid
      mediated inhibition affects the visual response properties of single cortical
      neurons. Simple neurons were depressed and complex neurons showed increase in the
      vigor and range of responses. Hypercomplex cells were no longer inhibited by
      elongated stimuli. The results are consistent with present evidence concerning
      the origin and distribution of inhibitory connections within the cortex.

PMID- 4354171
TI  - Nerve growth factor: relationship to the cyclic AMP system of sensory ganglia.
AB  - Nerve growth factor and N(6),O(2)' dibutyryl adenosine 3',5'-monophosphate both
      stimulate neurite elongation by explanted ganglia. However, the addition of nerve
      growth factor does not lead to increased amounts of adenosine 3',5'-monophosphate
      in intact ganglia, nor does it stimulate adenylate cyclase activity in broken
      ganglia cells.

PMID- 4354173
TI  - Estrogen-receptor interaction.
AB  - The interaction of estradiol with uterine cells involves the association of the
      hormone with an extranuclear receptor protein, followed by temperature dependent
      translocation of the resulting complex to the nucleus. During this process, the
      steroid binding unit of the protein undergoes an alteration, called "receptor
      transformation," that can be recognized by an increase in its sedimentation rate
      from 3.8S to 5.2S, and by its acquisition of the ability to bind to isolated
      uterine nuclei and to alleviate a tissue specific deficiency in the RNA
      synthesizing capacity of such nuclei. Receptor transformation can be effected in
      the absence of nuclei by warming uterine cytosol with estradiol. This preparation
      of transformed complex resembles that extracted from nuclei both in its
      sedimentation rate (5.3S) and in its ability to bind to uterine nuclei and
      augment RNA synthesis, properties that are not shown by the native complex. It is
      proposed that receptor transformation is an important step in estrogen action and
      that a principal role of the hormone is to induce conversion of the receptor
      protein to a biochemically functional form.

PMID- 4354174
TI  - Mutations in immunoglobulin-producing mouse myeloma cells.
AB  - Three mouse myeloma cell lines were cloned in soft agar and screened by an
      antiserum overlay method for variants defective in secretion of the myeloma
      protein. Variants that had lost the capacity to synthesize heavy chains arose
      spontaneously at a high rate of about 10(-3) per cell per generation. Such
      variants lost the capacity to produce light chains at a similarly high rate.
      After cells were treated with the acridine half mustard ICR-191, variants
      occurred with an even higher incidence, and some of these synthesized heavy
      chains differing from that of the parent.

PMID- 4354175
TI  - Neural micro- and macrostates.

PMID- 4354176
TI  - Evaluation of recovery from nondepolarizing neuromuscular block, using a digital
      neuromuscular transmission analyzer: preliminary report.

PMID- 4354177
TI  - [A quartz controlled threshold pacemaker using intensive integrated circuit
      technic].

PMID- 4354178
TI  - Mesotheliomata in rats after inoculation with asbestos and other materials.
AB  - Four experiments in which SPF Wistar rats were inoculated intrapleurally with
      asbestos or other materials are described. Mesotheliomata were observed in a
      considerable proportion of animals with all the samples of asbestos used and with
      a sample of brucite. A few were produced with synthetic aluminium silicate fibres
      and single ones with barium sulphate, glass powder and aluminium oxide. The risk
      of developing a mesothelioma at a given time after injection was approximately
      proportional to the dose. Of the UICC standard reference samples, crocidolite was
      the most carcinogenic and removal of the oils by benzene extraction did not alter
      the carcinogenicity of these samples. Chemical properties also seem unlikely to
      be the main factor producing mesotheliomata but the results support the
      hypothesis that the finer fibres are the more carcinogenic, and this is
      additional to the known aerodynamic advantage which the finer fibres have in
      penetrating to the periphery of the lung.

PMID- 4354180
TI  - Pediatric antimicrobial therapy IV.

PMID- 4354179
TI  - Human polyomavirus infection in renal allograft recipients.
AB  - Cytological and virological studies on 74 patients with functioning renal
      allografts were undertaken to detect polyomavirus infection of the renal tract.
      Ten patients (13.5%) were excreting polyomavirus. Virus particles were seen in
      the electron microscope in urine samples from eight patients. B.K. polyomavirus
      was isolated from four patients. Infection with a different polyomavirus was
      probable in one patient. Virus isolation was most readily achieved when large
      numbers of intact virus particles were seen in the urine. Patients who were
      excreting large amounts of polyomavirus shed numerous inclusion-bearing cells
      which could be detected by cytology. A serological study showed that the
      prevalence of B.K. antibody was similar to that found in the general population
      and 38% of this series of transplant patients had evidence of active infection
      with B.K. virus.

PMID- 4354181
TI  - [Incubation of gamma-cells, mother cells of the pituitary anterior lobe: with
      special reference to transformation of alpha-cells with addition of CRF and
      synthesis of ACTH].

PMID- 4354182
TI  - [Application of tissue culture to the study of ectopic hormone producing tumors].

PMID- 4354183
TI  - [Action of pantethine on the adrenal cortex of hypophysectomized rats].

PMID- 4354184
TI  - Growth impairment following irradiation in one of a pair of monozygotic twins.

PMID- 4354185
TI  - The effects of inactivity, programmed stimulation, and denervation on the
      histochemistry of skeletal muscle fiber types.

PMID- 4354186
TI  - Drug inhibition of PAH transport from cerobrospinal fluid in rabbits.

PMID- 4354188
TI  - Acute antiepileptic effects of 9-tetrahydrocannabinol in rats with kindled
      seizures.

PMID- 4354187
TI  - Effects of atropine, reserpine, 6-hydroxydopamine, and handling on seizure
      development in the rat.

PMID- 4354189
TI  - Magnetic resonance methods in membrane research.

PMID- 4354190
TI  - Adenyl cyclase activity in non-nucleated red blood cells: evidence for its
      localization in the reticulocytes.

PMID- 4354191
TI  - Intracellular enzymes in renal lymph as a measure of anoxic injury of the kidney.

PMID- 4354192
TI  - Depolarization by acetylcholine (ACH activation of triphosphoinositide
      phosphomonoesterase).

PMID- 4354193
TI  - Alkylating esters. VII. The metabolism of iso-propyl methanesulphonate and iso
      propyl iodide in the rat.

PMID- 4354194
TI  - Ineffectiveness of adrenocorticosteroids and adrenocorticotropin in altering Na-K
      currents in squid giant axon.

PMID- 4354195
TI  - A quantitative investigation of the response to injury of the central nervous
      system of rats treated with ACTH and triiodothyronine.

PMID- 4354197
TI  - Inhibition of cell proliferation caused by oncogenic DNA-polyoma virus.

PMID- 4354196
TI  - On mitochondrial inclusions in granulosa lutein cells of pregnant cows.

PMID- 4354198
TI  - Induction of active immune state by multinucleate tumour cells in mice.

PMID- 4354199
TI  - Splenic cellular responses in vitro after tumour-immunization.

PMID- 4354200
TI  - [Bronchial carcinoma associated with pulmonary tuberculosis].

PMID- 4354201
TI  - Hair tissue in the diagnosis of marasmus and kwashiorkor.

PMID- 4354202
TI  - Bone case of the month: fibrosarcoma.

PMID- 4354203
TI  - Congenital multiple hemivertebrae.

PMID- 4354204
TI  - Perspective: mental health.

PMID- 4354206
TI  - Phosphorylation of lysine-rich histone in the isolated perfused rat liver.
      Effects of glucagon, cyclic adenosine 3':5'-monophosphate, and insulin.

PMID- 4354205
TI  - Characterization of herpes simplex virus-induced deoxyribonucleic acid
      polymerase.

PMID- 4354207
TI  - N-methyl-2-anilinonaphthalene-6-sulfonyl peptides as fluorescent probes for
      pepsin-substrate interaction.

PMID- 4354208
TI  - Nucleotide sequence determination of bacteriophage T4 leucine transfer
      ribonucleic acid.

PMID- 4354209
TI  - Mechanisms regulating the concentration and the conformation of progesterone
      receptor(s) in the uterus.

PMID- 4354210
TI  - Electron paramagnetic resonance studies of manganese (II)-pyruvate kinase
      substrate complexes.

PMID- 4354211
TI  - Characterization of a proposed oxytocin receptor in rat mammary gland.

PMID- 4354212
TI  - Substrate-dependent, thiol-dependent, inactivation of pig brain nicotinamide
      adenine dinucleotide glycohydrolase.

PMID- 4354213
TI  - Malate dehydrogenase. XII. Initial rate kinetic studies of substrate activation
      of porcine mitochondrial enzyme by malate.

PMID- 4354214
TI  - Cell-free collagen synthesis on membrane-bound polysomes of chick embryo
      connective tissue and the localization of prolyl hydroxylase on the polysome
      membrane complex.

PMID- 4354215
TI  - Affinity chromatography and the purification of estrogen receptors.

PMID- 4354216
TI  - Pituitary growth retardation in children.

PMID- 4354217
TI  - The effect of high-frequency vibration on the activity of some enzymes
      (cytochrome oxidase, talase, peroxidase) participating in biological oxidation in
      experiment.

PMID- 4354218
TI  - Reaction of mice on infection with mycoplasma and leukosis viruses.

PMID- 4354219
TI  - Immunogenic properties of formalin herpes antigen prepared from cell cultures.

PMID- 4354220
TI  - Pituitary apoplexy in a child. Case report.

PMID- 4354221
TI  - [Antiviral activity of benzimidazole derivatives. 3. Benzimidazolyl methylketone
      and phenylketone derivatives].

PMID- 4354222
TI  - [Studies on the metabolism of cytochrome c heme octapeptide (CHP). 1.
      Preparations of 3H-labeled CHP and 35S-labeled CHP, and absorption, distribution
      and excretion of these compounds in the rats and mice by means of tracer
      technique and whole body autoradiography].

PMID- 4354223
TI  - [Functional state of the renin-hypertension-aldosterone system in chronic
      circulatory insufficiency].

PMID- 4354224
TI  - [Mixed tumor of the parotid gland of enormous dimensions].

PMID- 4354225
TI  - Attenuation of the morphine EEG continuum following a repeat dose within 16 days:
      delayed tolerance in the rat.

PMID- 4354226
TI  - Behavioural effects of dibutyryl cyclic 3',5' AMP, noradrenaline and cyclic 3',5'
      AMP in rats.

PMID- 4354227
TI  - [Significance of radiodiagnostical examinations of retroperitoneal neoplasms in
      early childhood].

PMID- 4354228
TI  - Isolation of a neurotropic type C virus.
AB  - A neurogenic paralysis of the lower limb can be induced and serially transmitted
      in mice by a nontransforming type C virus strain that originated in an embryo of
      a wild mouse. The virus exerted a neurotropic effect on the anterior horn
      neurons.

PMID- 4354229
TI  - Regulation of phosphodiesterase synthesis: requirement for cyclic adenosine
      monophosphate-dependent protein kinase.
AB  - Endogenous cyclic adenosine monophosphate (AMP) and its dibutyryl derivative
      increase cyclic AMP phosphodiesterase activity in cultured lymphoma cells. This
      effect is prevented by cycloheximide. A variant population of cells deficient in
      cyclic AMP-dependent protein kinase contains lower basal phosphodiesterase
      activity, which cannot be induced by cyclic AMP.

PMID- 4354230
TI  - Comparative studies on bacterial 5S ribosomal RNA.

PMID- 4354231
TI  - Protein binding of nicotinamide adenine dinucleotide and regulation of
      nicotinamide adenine dinucleotide glycohydrolase activity in homogenates of
      rabbit skeletal muscle.

PMID- 4354232
TI  - Activity of foot-and-mouth disease virus RNA-dependent RNA polymerase in vitro:
      inhibition by polyamines and poly(amino acid)s.

PMID- 4354233
TI  - Ligand-induced conformational states of rabbit liver fructose 1,6-bisphosphatase
      as revealed by digestion with subtilisin.

PMID- 4354234
TI  - Bull semen nicotinamide adenine dinucleotide nucleosidase. VI. Fluorescence
      studies of the enzyme with reduced nicotinamide adenine dinucleotide.

PMID- 4354235
TI  - Carbohydrate composition of rat hepatocyte nuclear membrane as compared to
      normal, Morris hepatoma 7800, and phenobarbital-induced microsomal membranes.

PMID- 4354236
TI  - Relation between the time at which cytopathic endpoint occurs in infected
      cultures and the initial infective virus dose, with application to the study of
      inhibitors of cytopathic effect.

PMID- 4354238
TI  - Enhancement of immunizing potency of a foot-and-mouth disease vaccine for cattle
      by treatment of the antigen with formaldehyde.

PMID- 4354237
TI  - Electron microscopy of porcine cytomegalovirus. Viral crystalline arrays and
      viral forms in the nasal mucosa of piglets.

PMID- 4354239
TI  - Growth of rhinovirus type 14. Brief report.

PMID- 4354240
TI  - A simple viability test of cells producing viral antigen. Brief report.

PMID- 4354241
TI  - The significance of failure to isolate infectious viruses in cases of subacute
      sclerosing panencephalitis. Brief report.

PMID- 4354242
TI  - Physical adsorption of respiratory viruses to polystyrene tubes. Brief report.

PMID- 4354244
TI  - Bile duct carcinoma in chronic ulcerative colitis.

PMID- 4354245
TI  - Auto-antibodies in cirrhosis and hepatocellular carcinoma.

PMID- 4354246
TI  - The chemical diagnosis of ganglioneuroma and neuroblastoma using random specimens
      of urine.

PMID- 4354243
TI  - [Pregnancy-induced leukocyte-(HL-A) antibodies].

PMID- 4354247
TI  - Lesch-Nyhan syndrome: absence of the mutant enzyme in erythrocytes of a
      heterozygote for both normal and mutant hypoxanthine-guanine phosphoribosyl
      transferase.

PMID- 4354248
TI  - Electrophoretic properties of hypoxanthine-guanine phosphoribosyl transferase in
      erythrocytes of subjects with Lesch-Nyhan syndrome.

PMID- 4354249
TI  - Transmembrane potentials and phospholipid flip-flop in excitable membrane
      vesicles.

PMID- 4354250
TI  - Detection of two restriction endonuclease activities in Haemophilus
      parainfluenzae using analytical agarose--ethidium bromide electrophoresis.

PMID- 4354251
TI  - Ascites tumor ribonucleic acid polymerases. Isolation, purification, and factor
      stimulation.

PMID- 4354252
TI  - Specific cytoplasmic glucocorticoid hormone receptors in lactating mammary
      glands.

PMID- 4354253
TI  - Specific estrogen receptors in the lactating mammary gland of the rat.

PMID- 4354254
TI  - Cyclic adenosine 3',5'-monophosphate dependent phosphorylation of ribosomal
      proteins from bovine anterior pituitary gland.

PMID- 4354255
TI  - Purification of particulate glucose-6-phosphatase.

PMID- 4354256
TI  - Decline in glucose-6-phosphatase activity during prolonged postfixation washing.

PMID- 4354257
TI  - A survey of the different methods used. Experimental study on the application of
      some methods found suitable to our country.

PMID- 4354258
TI  - Inhibition and enhancement of the noradrenaline constrictor response by
      methylxanthines.

PMID- 4354259
TI  - Evidence for an angiotensinogen-stimulating factor after nephrectomy.

PMID- 4354260
TI  - Nonspecific entry of thoracic duct immunoblasts into intradermal foci of
      antigens.

PMID- 4354261
TI  - Nuclear differentiation and nucleic acid synthesis in well-fed exconjugants of
      Paramecium aurelia.

PMID- 4354262
TI  - [Brain tumors in the aged].

PMID- 4354263
TI  - [Biochemical shifts in rats during muscular activity under different temperature
      conditions].

PMID- 4354264
TI  - [Participation of the hypophysis and adrenals in regulation of intraocular
      pressure].

PMID- 4354265
TI  - [Participation of the cholinoreactive structures of the cortex in reproduction of
      the electrical "signs" of a temporal connection].

PMID- 4354266
TI  - [Radiologically recognisable local complications of alloplastic hip replacement
      (total prosthesis)].

PMID- 4354267
TI  - [Degenerative changes in the costo-transverse and costovertebral joints].

PMID- 4354268
TI  - [Radiographic studies of the esophagus with Buscopan hypotension].

PMID- 4354269
TI  - [Optimal tomographic demonstration of the inner ear canal].

PMID- 4354270
TI  - [Unusual course of localised myositis ossificans with radiation therapy].

PMID- 4354271
TI  - [Radiation therapy of the Kasabach-Merritt syndrome].

PMID- 4354272
TI  - [Combined anomaly of inferior vena cava as a cause of recurring pelvic vein
      thromboses].

PMID- 4354273
TI  - [Isometry of aortic arch].

PMID- 4354274
TI  - [Primary melanoma of nasal cavity].

PMID- 4354275
TI  - [Rare tumours of the duodenum and their differential diagnosis].

PMID- 4354276
TI  - [Angiographic control of peripheral spleno-renal anastomosis for portal
      hypertension].

PMID- 4354277
TI  - [The radiological findings due to infection by Yersinia pseudotuberculosis and
      Yersinia enterocolitica--observation of five cases].

PMID- 4354279
TI  - [Lympho-venous anastomoses: diagnosis, differential diagnosis and drainage].

PMID- 4354278
TI  - [Lymphographic findings following lymphadenectomy. A contribution to the problem
      of lymph vessel regeneration].

PMID- 4354280
TI  - [Roentgenologic signs of disturbed calcium metabolism in dialysis patients. I.
      Frequency of roentgenologic skeletal changes].

PMID- 4354281
TI  - [Tumour induced, non-specific cortical reactions].

PMID- 4354282
TI  - [The radiology and nomenclature of metaphyseal bone defects in adolescence].

PMID- 4354283
TI  - [Positive arthrography for the demonstration of pathological changes in the
      popliteal bursa].

PMID- 4354284
TI  - [The local kinetics of 87m Sr in joint diseases in comparison with the results of
      113M In].

PMID- 4354285
TI  - Carcinogenic effect of N-methyl-N'-nitro-N-nitrosoguanidine with various kinds of
      surfactant in the glandular stomach of rats.

PMID- 4354286
TI  - Effect of adenosine3', 5'-monophosphate on thymidine kinase in tumor cells.

PMID- 4354287
TI  - Heterogeneity of ferritin from 3'-methyl-4-(dimethylamino) azobenzene-induced
      hepatomas.

PMID- 4354288
TI  - Mucopolysaccharides of rat ascites hepatoma cells.

PMID- 4354289
TI  - Production of growth-and differentiation-stimulating factors for mouse leukemia
      cells by different cell species.

PMID- 4354290
TI  - Immuno-electron microscopic studies on cell surface antigens of Friend virus
      induced tumor in the rat.

PMID- 4354292
TI  - Multinucleated giant cell formation in cultured cells by murine leukemia virus
      infection.

PMID- 4354291
TI  - Chromosomal aberrations of a lymphoblastoid cell line by experimental infection
      with Epstein-Barr virus.

PMID- 4354294
TI  - Human plasma iron responses following test doses of iron from known sources.

PMID- 4354293
TI  - [Influence of ACTH, metopirone and cortisone on central regulatory centers].

PMID- 4354295
TI  - [Effect of garlic extract in prevention of virus infections].

PMID- 4354296
TI  - [Acute gastroduodenal ulcer (review of the literature)].

PMID- 4354297
TI  - Comparison of glucose-6-phosphatase activity in unfertilized and fertilized sea
      urchin egg fractions.

PMID- 4354298
TI  - Reconstruction of the primary sequence of a protein from peptides of known
      sequence.

PMID- 4354299
TI  - [Hepatoma with serum alpha-1-fetoprotein simulating secondary liver carcinoma].

PMID- 4354300
TI  - [Immunoglobulin M and congenital infectious abnormalities].

PMID- 4354301
TI  - [30 cases of Crohn's disease].

PMID- 4354302
TI  - [Lupus associated with ileocolitis following tuberculostatic treatment ( lupus
      and Crohn's disease )].

PMID- 4354303
TI  - [Liver tolerance of antitubercular treatment including rifampicin. Study on 214
      cases].

PMID- 4354304
TI  - [Kidney function tests in medical practice].

PMID- 4354305
TI  - [Diagnosis of jaundice].

PMID- 4354306
TI  - [Hemangiolymphoma with malignant course. Apropos of a case].

PMID- 4354307
TI  - [Medical causes of mental retardation].

PMID- 4354309
TI  - Smooth muscle-like cells in ovaries of the hamster and gerbil.

PMID- 4354308
TI  - [Demonstration of specific antibodies in the amniotic fluid].

PMID- 4354310
TI  - Fluorescence and electron microscopy of the monoamine-containing cells in the
      turtle heart.

PMID- 4354311
TI  - A quantitative electron microscopic analysis of myelination in the optic nerve of
      suckling rats treated with an inhibitor of cholesterol biosynthesis.

PMID- 4354312
TI  - Mediastinoscopic observations of metastatic spread in pulmonary carcinoma.

PMID- 4354313
TI  - Mechanism of enzyme action.

PMID- 4354314
TI  - Toward molecular mechanisms of developmental processes.

PMID- 4354315
TI  - The cell surface membrane: biochemical aspects and biophysical probes.

PMID- 4354316
TI  - Stimulation of polypeptide synthesis by cyclic 3'-5'-guanosine monophosphate.

PMID- 4354318
TI  - Effects of 2,4-substituents of deuteroheme upon peroxidase functions. II.
      Reactions of peroxidases and metmyoglobin with azide, cyanide and fluoride.

PMID- 4354317
TI  - Studies on calciferol metabolism. VII. The effects of actinomycin D and
      cycloheximide on the metabolism, tissue and subcellular localization, and action
      of vitamin D3.

PMID- 4354319
TI  - The b cytochromes in succinate--cytochrome c reductase from pigeon breast
      mitochondria.

PMID- 4354320
TI  - Bull semen nicotinamide adenine dinucleotide nucleosidase. VII. Nonenzymatic
      basis of apparent transglycosidation with histamine.

PMID- 4354322
TI  - Cytochrome c interaction with membranes. II. Comparative study of the interaction
      of c cytochromes with the mitochondrial membrane.

PMID- 4354321
TI  - Receptors for glucocorticoids in lung tissue.

PMID- 4354324
TI  - [Zollinger-Ellison syndrome with carcinoid islet endocrine tumor with primary
      gallbladder localization].

PMID- 4354323
TI  - The effects of actin on the electron spin resonance of spin-labeled myosin.

PMID- 4354325
TI  - The activities of pyruvate carboxylase, phosphoenolpyruvate carboxylase and
      fructose diphosphatase in muscles from vertebrates and invertebrates.
AB  - 1. The activities of pyruvate carboxylase, phosphoenolpyruvate carboxylase and
      fructose diphosphatase in crude homogenates of vertebrate and invertebrate
      muscles are reported. 2. Pyruvate carboxylase activity was present in all insect
      flight muscles that were investigated: in homogenates of bumble-bee flight muscle
      the activity was inhibited by ADP and activated by acetyl-CoA, and it was
      distributed mainly in the mitochondrial fraction. This is the first demonstration
      of pyruvate carboxylase activity in muscle. However, the activity appears to be
      restricted to insect flight muscle, since it was not found in other invertebrate
      or vertebrate muscles. 3. Since the three enzymes were never found together in
      the same muscle, it is concluded that these enzymes cannot provide a pathway for
      the synthesis of glycogen from lactate or pyruvate in muscle. Other roles for
      these enzymes in muscle are suggested. In particular, pyruvate carboxylase may be
      present in insect flight muscle for the provision of oxaloacetate to support the
      large increase in activity of the tricarboxylic acid cycle which occurs when an
      insect takes flight.

PMID- 4354326
TI  - Effects of Naja nivea venom on nerve, cardiac and skeletal muscle activity of the
      frog.
AB  - 1. The effects of 1 mg/ml whole Naja nivea (Cape cobra) venom, and of three
      different toxins isolated from it, on spinal reflex excitability and cardiac and
      skeletal muscle activity of the frog (Xenopus laevis), were studied. Isolated
      spinal cords, sciatic nerve-gastrocnemius muscle units and isolated heart
      preparations were used.2. Synaptic efficiency and/or motoneurone excitability
      ceased totally and irreversibly after the application of whole venom within 18.5
      minutes. The application of alpha toxin caused polysynaptic reactivation of the
      motoneurones after the monosynaptic response elicited by electrical stimulation,
      i.e. it had an excitatory effect, which was retained after washing off the toxin.
      The effect of beta toxin resembled that of alpha toxin, except that the effect
      was lost after the toxin was washed off. The delta toxin abolished all nervous
      reactivity irreversibly and was found to be 2.64 times more effective in this
      respect than whole venom.3. Responses of the gastrocnemius muscle to electrical
      stimulation of its motor nerve ceased 10 to 20 min after application of the
      venom. The muscle usually still responded slightly to direct stimulation for a
      few minutes. The effect was irreversible. The venom did not only block
      neuromuscular transmission, but also affected the muscle fibre itself. Nerve
      conductivity was relatively resistant to the venom; alpha and beta toxins
      produced similar results but were less effective.4. The application of whole
      venom (1 mg/ml) to the isolated heart resulted in complete spasm of the ventricle
      within 3 to 8 minutes. The atria continued contracting long after the ventricle
      ceased. When the venom was washed off, contractions of the atria were restored,
      while the ventricle remained irreversibly in a state of spasm. The alpha, beta
      and delta toxins weakened the contractions of the ventricle, but did not produce
      spasm. The effect on the ventricle was reversible. Contractions of the atria
      remained apparently unaltered.

PMID- 4354327
TI  - Atropine sulphate absorption from an intramuscular injection of a mixture of the
      oxime, P2S, and atropine in exercising humans.

PMID- 4354328
TI  - Specificity of adenosine on transmitter output at the neuromuscular junction.

PMID- 4354330
TI  - Chronic dorsal root section on free amino acid levels in the rabbit spinal cord.

PMID- 4354329
TI  - Analysis of labile brain constituents using a technique for the instantaneous
      fixation of brain tissue in vivo.

PMID- 4354331
TI  - An antibody survey of children in an Ottawa public school.

PMID- 4354332
TI  - [Use of HeLa cells in the color microtest for the determination of serum
      neutralizing antibodies against polioviruses. I].

PMID- 4354333
TI  - Evidence for a catalytic-centre heterogeneity of molybdoferredoxin from
      Clostridium pasteurianum.

PMID- 4354334
TI  - Fixation of a Salmonella minnesota R-form glycolipid on the membrane of normal
      and transformed rat-embryo fibroblasts.

PMID- 4354335
TI  - The flux of pyruvate in perfused rat heart.

PMID- 4354336
TI  - The effect of insulin and growth hormone on the flux of tracer from labelled
      lactate in perfused rat heart.

PMID- 4354337
TI  - Adenylate-cyclase receptors for adrenergic neurotransmitters in rat cerebral
      cortex.

PMID- 4354339
TI  - The neutral proteases of human granulocytes. Isolation and partial
      characterization of two granulocyte collagenases.

PMID- 4354338
TI  - Relationships between intracellular contents of nucleotides and 5-phosphoribosyl
      1-pyrophosphate in Escherichia coli.

PMID- 4354340
TI  - Formation of the yeast mitochondrial membrane. 1. Effects of inhibitors of
      protein synthesis on the kinetics of enzyme appearance during glucose
      derepression.

PMID- 4354341
TI  - ATP-controlled fatty-acid synthesis in cultured arterial fibroblasts.

PMID- 4354342
TI  - Magnetic-resonance studies of the interactions between bovine-serum albumin and
      surfactants. 1. Nature of binding site.

PMID- 4354343
TI  - Magnetic-resonance studies of the interactions between bovine-serum albumin and
      surfactants. 2. Effect of surfactants on the structure of bovine-serum albumin.

PMID- 4354344
TI  - Tyrosine substitutions resulting from suppression of amber mutants of iso-1
      cytochrome c in yeast.

PMID- 4354345
TI  - Confirmation of UAG as a nonsense codon in bakers' yeast by amino acid
      replacements of glutamic acid 71 in iso-1-cytochrome c.

PMID- 4354347
TI  - Evolution of transfer RNA.

PMID- 4354346
TI  - DNA synthesis in polyoma virus infection. II. Relationship between viral DNA
      replication and initiation of cellular DNA replicons.

PMID- 4354348
TI  - [Central nervous diseases and enzyme activity of the cerebrospinal fluid].

PMID- 4354349
TI  - [Autonomic neuronal system and "neurodystonia"].

PMID- 4354350
TI  - An in vitro assay for corticotropin releasing factor(s) using suspensions of
      isolated pituitary cells.

PMID- 4354353
TI  - [Current aspects of research on the physiology of the duodenal junction].

PMID- 4354354
TI  - [Preliminary report on eye-frequenting butterflies in the Ivory Coast].

PMID- 4354355
TI  - Autoimmune thrombocytopenia occurring in a young woman with idiopathic
      haemochromatosis.

PMID- 4354356
TI  - [Periodic respiration].

PMID- 4354358
TI  - [Hodgkin's disease with principal hepatic localization and peliosis lesions.
      Apropos of a case].

PMID- 4354357
TI  - [Pancreatic cancer with parathormone secretion. 2 new cases].

PMID- 4354359
TI  - [Transfusional malaria. Value of serodiagnosis for prevention].

PMID- 4354361
TI  - [Lymphoid myelofibrosis. Apropos of 4 new cases].

PMID- 4354360
TI  - [Various aspects of eye injuries].

PMID- 4354362
TI  - [Value of epsilon-aminocaproic acid in radiological examinations].

PMID- 4354363
TI  - [Physiopathological mechanisms of post-traumatic epilepsy].

PMID- 4354364
TI  - [Total pancreatectomy in Japan].

PMID- 4354365
TI  - Interaction of glucocorticoids with rat liver nuclei. I. Role of the cytosol
      proteins.

PMID- 4354366
TI  - Interaction of glucocorticoids with rat liver nuclei. II. Studies on the nature
      of the cytosol transfer factor and the nuclear acceptor site.

PMID- 4354367
TI  - Purification of (14C) protocollagen and its hydroxylation by prolyl-hydroxylase.

PMID- 4354368
TI  - Synthesis of four undecanucleotides complementary to a region of the coat protein
      cistron of phage fd.

PMID- 4354369
TI  - Circular dichroism of liver alcohol dehydrogenase complexes with auramine O.

PMID- 4354370
TI  - Effect on coenzyme on the bis(8-anilino-1-naphthalenesulfonate)-linked
      association of beef muscle lactic dehydrogenase.

PMID- 4354371
TI  - Lanthanide ions activate alpha-amylase.

PMID- 4354372
TI  - Cooperativity in human erythrocyte phosphofructokinase.

PMID- 4354373
TI  - Elevated levels of acceptor activity of hepatoma transfer ribonucleic acid.

PMID- 4354374
TI  - Spectrophotometric assay of 2',3'-cyclic nucleotide 3'-phosphohydrolase:
      application to the enzyme in bovine brain.

PMID- 4354376
TI  - Increased shock sensitivity in rats with experimental allergic encephalomyelitis
      and reversal by 5-hydroxytryptophan.

PMID- 4354375
TI  - Excitatory effects of 5-hydroxytryptamine in the hippocampal-septal circuit.

PMID- 4354377
TI  - Bicuculline and picrotoxin sensitive inhibition in interpositus neurones of cat.

PMID- 4354378
TI  - A simple preparation of bicuculline methiodide, a water-soluble GABA antagonist.

PMID- 4354380
TI  - Short-term changes in the firing pattern of hypothalamic neurons during Pavlovian
      conditioning.

PMID- 4354379
TI  - Subarachnoid versus ventricular perfusion in the rabbit.

PMID- 4354381
TI  - Hypothermia--a practical aid in veterinary surgery.

PMID- 4354382
TI  - [Brain metabolism with reduced blood perfusion volume].

PMID- 4354383
TI  - Synthesis and evaluation of the anticancer activity of a new series of
      methanesulfonates.

PMID- 4354384
TI  - Focal rhythmic EEG slowing with temporal lobe tumors. Report of six cases.

PMID- 4354385
TI  - The influence of topically applied D-tubocurarine on the taste-induced electrical
      nerve activity in the frog.

PMID- 4354386
TI  - [Viability of enteroviruses in the alkaline and acid effluents of Gaiskii Ore
      Dressing Combine].

PMID- 4354387
TI  - [Sanitary virological study of the effectiveness of sewage decontamination on
      agricultural irrigation fields].

PMID- 4354388
TI  - Lipolytic activity of rat pituitaries in vitro.

PMID- 4354389
TI  - The role of transcortin in the distribution of corticosterone in the rat.

PMID- 4354390
TI  - Plasma calcitonin-like activity and urinary cyclic adenosine monophosphate during
      pregnancy, parturition, and lactation in cows with parturient hypocalcemia.

PMID- 4354391
TI  - Influence of median eminence extracts on neosynthesis and release of ACTH.

PMID- 4354392
TI  - Biological ACTH activity of lipid mobilizing peptide fractions from hog
      pituitaries.

PMID- 4354393
TI  - Fatty changes and hepatic cell excretion in avian liver. An electron
      microscopical study of Kepone toxicity.

PMID- 4354395
TI  - Lipid characterization of bovine serum lipoproteins throughout gestation and
      lactation.

PMID- 4354394
TI  - Experimental infections with Pasteurella septica (sero-group A) and an adeno-or
      enterovirus in gnotobiotic piglets.

PMID- 4354396
TI  - Inhibition of urea on the hepatocarcinogensis induced by N, N-dimethyl-4
      aminoazobenzene in rats.

PMID- 4354397
TI  - Multiple cerebral gliomas in multiple sclerosis.
AB  - A patient with multiple sclerosis and a multicentric anaplastic astrocytoma is
      described. The evidence suggests that the relationship is not coincidental and
      that the astrocytomas originate in multiple sclerosis plaques.

PMID- 4354398
TI  - Modulation of postural reflexes by voluntary movement. II. Modulation at an
      inactive joint.
AB  - We have observed that there is a brief, 400 msec period of widespread
      facilitation of both the Hoffmann and the tendon-jerk reflexes associated with
      the initiation of a variety of local, voluntary, isometric efforts. It is
      suggested that the site of this facilitation lies within the spinal cord. We have
      also observed that this period is followed, for the Hoffmann reflex, by a period
      of spinal inhibition. By contrast, the tendon-jerk is facilitated, at a reduced
      level, for at least another 500 msec by mechanisms probably working at the muscle
      spindle. These results are discussed in comparison with experiments involving
      activation of the reflex agonist and antagonist muscles. It is proposed that
      voluntary control of the locomotor system is organized through separate
      mechanisms for muscle recruitment and for regulation of the sensitivity of the
      myotatic reflex loop.

PMID- 4354399
TI  - Comparison of the tonic stretch reflex in athetotic patients during rest and
      voluntary activity.
AB  - An electromyographic technique was used to record the tonic stretch reflex (TSR)
      responses to passive sinusoidal stretching of biceps brachii muscle in athetotic
      patients. The TSR transmission characteristics measured while the patient was in
      a relaxed state were compared with those measured while the patient was
      voluntarily active. The resting TSR and action TSR were found to differ markedly.
      Sensitivity, pattern, duration, and timing of the TSR responses were all changed
      during voluntary activity. The results suggest that the TSR in athetosis is
      functionally reorganized by supraspinal influences during voluntary activity. It
      is proposed that athetoid movements and action tremor may be a manifestation of
      abnormal action TSR caused by faulty supra-spinal control during activity.

PMID- 4354400
TI  - Significance of plasma lysolecithin in patients with multiple sclerosis: a
      longitudinal study.
AB  - Five patients with multiple sclerosis and four normal subjects have been followed
      for over two years. Plasma phospholipid levels and phospholipid fatty acid
      composition have been assayed periodically. The increased amount of plasma
      lysolecithin already described by us has been confirmed in this longitudinal
      study. A significant increase in saturated fatty acids of lysolecithin has also
      been demonstrated. In contrast, the lecithin concentration and fatty acid
      composition do not show any significant variations. The lysolecithin
      saturated/unsaturated fatty acid ratio was different in the same patients at
      different times, but no correlation was established between these variations and
      the clinical symptoms measured using the Kurtzke scale. The possible significance
      of saturated fatty acid increase in lysolecithin in the pathogenetic mechanisms
      of multiple sclerosis is discussed.

PMID- 4354401
TI  - Renshaw cell activity in man.
AB  - The H-reflex elicited in triceps surae by percutaneous stimulation of the
      posterior tibial nerve was conditioned by stimuli applied through the same
      electrode. The differential sensitivity of motor and sensory fibres to duration
      of the stimulus pulse made it possible to condition the H-reflex with either a
      motor or a sensory stimulus. With both types of conditioning, the H-reflex was
      inhibited at conditioning-test intervals of 2-3 msec and was then facilitated,
      the peak of facilitation occurring at 5-8 msec with motor conditioning and 6-10
      msec with sensory conditioning. The phase of facilitation was followed by further
      inhibition. We have concluded (1) that the effects of motor conditioning on the H
      reflex result from the discharge of Renshaw cells activated by the antidromic
      volley in the motor axons, and (2) that the effects of sensory conditioning (at
      the times used in these experiments) are largely due to the activation of Renshaw
      cells secondary to the discharge of alpha motoneurones by the conditioning
      volley.

PMID- 4354402
TI  - Some effects of chloramphenicol and ethidium bromide on Tetrahymena pyriformis.

PMID- 4354403
TI  - The enzymic synthesis of dihydropteroate and dihydrofolate by Plasmodium berghei.

PMID- 4354404
TI  - Two improved methods for the determination of soluble carbohydrates.

PMID- 4354405
TI  - An operon for histidine biosynthesis in Streptomyces coelicolor. II. Biochemical
      evidence.

PMID- 4354406
TI  - Cure of the child with cancer.

PMID- 4354408
TI  - Clostridial brain abscess and hyperbaric oxygen.

PMID- 4354409
TI  - Biogenic monoamines in the cyclostome and lower vertebrate brain.

PMID- 4354407
TI  - Bell's palsy and its treatment.

PMID- 4354410
TI  - Understanding biochemical pathology of depressive illness. An overview.

PMID- 4354411
TI  - [Immunity and tumors. Immunologic diagnosis of onco-fetal antigenic tumors].

PMID- 4354412
TI  - [Study of tachyphylaxis due to angiotensin on the isolated aorta in rats. Effect
      of norepinephrine, tyramine, reserpine and phenoxybenzamine].

PMID- 4354414
TI  - [Etiology of diseases of the respiratory organs in calves].

PMID- 4354413
TI  - Paraneoplastic syndromes. A clinically relevant concept in cancer.

PMID- 4354415
TI  - [Spread of the fowl pox virus by D. gallinae ticks].

PMID- 4354416
TI  - [Method for the presentation of the thoracic duct by means of enteral resorption
      of iodized oils (experiments with dogs and cats)].

PMID- 4354417
TI  - [Significance of tryptophan-perchloric acid reaction in malignant tumors].

PMID- 4354420
TI  - Mechanism of the short-term poststimulatory depression of the cochlear
      microphonics (hysteresis).

PMID- 4354419
TI  - [Relationship between Herpes simplex virus type 2 and carcinoma of the uterine
      cervix].

PMID- 4354421
TI  - [The biological activities of cytochrome c hemeoctapeptide (CHP). 1. The effects
      of CHP against the tissue damage caused by experimental hypoxia].

PMID- 4354422
TI  - [Values and limitation of clinical electroencephalography. Supplement 3. Future
      possibility of electroencephalographic test during all night sleep--partial sleep
      interruption and simultaneous administration of L-dopa].

PMID- 4354423
TI  - [Case of mediastinal hemangiofibroma].

PMID- 4354424
TI  - [Seeding of ponds and carp with Clostridium perfringens bacilli].

PMID- 4354425
TI  - Faith healing-Pennsylvania style.

PMID- 4354426
TI  - Granulomatous disease of the lungs.

PMID- 4354428
TI  - The radiographic presentation of pulmonary opportunistic inflammatory disease.

PMID- 4354427
TI  - The radiology of bacterial and viral pneumonias.

PMID- 4354430
TI  - Homeostasis and the prostaglandins.

PMID- 4354431
TI  - [Studies of the free fatty acid pattern in blood plasma in experimental
      neurogenic-interoceptive hypertension and during administration of angiotension
      II in the rabbit].

PMID- 4354429
TI  - Bronchographic criteria of inflammatory disease and radiologic lung biopsy
      techniques.

PMID- 4354432
TI  - [The hippocampus and inhibitory processes].

PMID- 4354434
TI  - [Conditioned reactions to time in neurons of the amygdaloid complex].

PMID- 4354433
TI  - [Participation of the structures of the hippocampal circle in the formation of
      external inhibition].

PMID- 4354435
TI  - [The significance of intervals between "conditioned" and "unconditioned" stimuli
      in the process of elaboration of cellular analogs of temporary connections].

PMID- 4354436
TI  - [A decrease in uncertainty in the flow of impulses from hippocampal neurons in
      response to a stimulus].

PMID- 4354437
TI  - Proline hydroxylase in injury-induced arteriosclerosis.

PMID- 4354438
TI  - Polyol pathway activity in aorta.

PMID- 4354439
TI  - Clinical amoebiasis syndrome and case reports of a few unusual cases of
      amoebiasis.

PMID- 4354440
TI  - The identification and semi-quantitative assay of some fat-soluble vitamins and
      antioxidants in pharmaceutical products and animal feeds by thin-layer
      chromatography.

PMID- 4354441
TI  - Hormones and gene expression.

PMID- 4354442
TI  - Netherlands Society for Microbiology meeting at Delft on 25 October 1972.
      Homologies in the amino acid sequences of cytochrome c-555 from the green
      photosynthetic bacteria "Chloropseudomonas ethylica" and Chlorobium
      thiosulfatophilium.

PMID- 4354443
TI  - Effects of ACTH, adrenalectomy and time of day on emotional activity of the rat.

PMID- 4354444
TI  - Lymphocyte activation: the dualistic effect of cAMP.

PMID- 4354446
TI  - A novel monosialoganglioside synthesized by a rat brain cytidine-5'-monophospho-N
      acetylneuraminic acid: galactosyl-N-acetylgalactosaminyl-galactosyl
      glucosylceramide sialyltransferase.

PMID- 4354445
TI  - Cyclic 3',5'-AMP phosphodiesterase of Neurospora crassa.

PMID- 4354447
TI  - Quiescent SV40 virus transformed 3T3 cells in culture.

PMID- 4354448
TI  - The activation of adenylate cyclase. II. The postulated presence of (A) adenylate
      cyclase in a phospho (inhibited) form (B) a dephospho (activated) form with a
      cyclic adenylate stimulated membrane protein kinase.

PMID- 4354449
TI  - The occurrence of fluoride stimulated membrane phosphoprotein phosphatase.

PMID- 4354451
TI  - Evidence for RNA-linked nascent strands in polyoma virus DNA replication.

PMID- 4354452
TI  - Decreased binding of insulin to its receptors in rats with hormone induced
      insulin resistance.

PMID- 4354453
TI  - A 5'-amino analog of adenosine diphosphate.

PMID- 4354450
TI  - Synthesis of the E. coli pyruvate dehydrogenase complex: non-dependence on 3'-5'
      cyclic AMP.

PMID- 4354454
TI  - Studies on the in vitro effects of insulin on glycogen synthesis and
      ultrastructure in isolated rat liver hepatocytes.

PMID- 4354456
TI  - Changes of the activities of adenyl cyclase and cAMP-phosphodiesterase and of the
      level of 3'5' cyclic adenosine monophosphate in rat mammary gland during
      pregnancy and lactation.

PMID- 4354455
TI  - The messenger-directed synthesis of the alpha-fragment of the enzyme beta
      galactosidase.

PMID- 4354457
TI  - Kinetic and molecular characteristics of allosteric pyruvate kinase from muscle
      tissue of the sea mussel Mytilus edulis L.

PMID- 4354458
TI  - Glucose-6-phosphatase activity in a soluble fraction from cotyledon tissue of
      Brassica nigra.

PMID- 4354459
TI  - Effects of sulfhydryl reagents on synthetic and hydrolytic activities of
      multifunctional glucose-6-phosphatase.

PMID- 4354460
TI  - Properties of adenylate cyclase in mucosal cells of the rabbit ileum and the
      effect of cholera toxin.

PMID- 4354461
TI  - Collagenase activity in homogenates of the involuting rat uterus.

PMID- 4354462
TI  - Effect of spermine on the reaction catalyzed by threonyl-tRNA synthetase from rat
      liver.

PMID- 4354464
TI  - Prostaglandin E1 and platelets.

PMID- 4354463
TI  - Comparative morphometric study of the human pancreas in its normal state and in
      primary chronic calcifying pancreatitis.

PMID- 4354465
TI  - Effect of pyrazole on ACTH stimulated lipolysis "in vivo".

PMID- 4354466
TI  - Study of steatosis induced in the rat by orotic acid.

PMID- 4354467
TI  - Prognosis of early bronchogenic carcinoma. Survival curves of 451 patients after
      resection of lung cancer in relation to the results of pre-operative tuberculin
      skin test.

PMID- 4354469
TI  - Activation of endogenous C-type oncornavirus by 5-bromodeoxyuridine in cultured
      embryonic rat fibroblasts.

PMID- 4354468
TI  - Direct stimulant effect of cyclic AMP and dibutyryl cAMP on glycogenolysis by
      hepatocytes in histiotypic culture.

PMID- 4354470
TI  - [Alpha 1-fetoprotein in liver diseases and metabolic disorders in children].

PMID- 4354471
TI  - [Fluorescence serological and histological studies on CELO-virus infected chick
      embryos].

PMID- 4354472
TI  - [Seroepidemiology of 10 infectious diseases in children in Mexico City. Measles,
      rubella, parotitis, typhoid, whooping cough, amebiasis, influenza and adenovirus
      infections, Mycoplasma pneumoniae and herpes simplex].

PMID- 4354473
TI  - Immunological responses of rabbits artificially infested with the cattle grubs
      Hypoderma bovis (L.) and H. Lineatum (De Vill.) (Diptera: Oestridae).

PMID- 4354474
TI  - Experimental genital herpes infection of the marmoset.

PMID- 4354475
TI  - Production of non-defective and defective oligomers of viral DNA in mouse 3T3
      cells transformed by a thermosensitive mutant of polyoma virus.

PMID- 4354476
TI  - Nuclear magnetic resonance study of exchangeable protons in ferrocytochrome c.

PMID- 4354477
TI  - Defective interfering particles of poliovirus. II. Nature of the defect.

PMID- 4354478
TI  - Defective interfering particles of poliovirus. 3. Interference and enrichment.

PMID- 4354479
TI  - [Clinical study of ophthalmoplegia--differential diagnosis of central and
      peripheral nervous system diseases].

PMID- 4354480
TI  - Localization of free radicals on irradiated deoxyribonucleohistone.

PMID- 4354481
TI  - Renal failure, uncontrollable thirst, and hyperreninemia. Cessation of thirst
      with bilateral nephrectomy.

PMID- 4354482
TI  - [Mechanism of neuromuscular transmission. The effect of succinylcholine chloride
      on phase II block, with special reference to the effect of a small amount of d
      tubocurarine on preparalytic facilitation].

PMID- 4354483
TI  - [Calcification in abdominal x-ray photographs and its significance. 2].

PMID- 4354484
TI  - [A forgotten sign. "Brush" picture of Egas Moniz].

PMID- 4354485
TI  - Snoring.

PMID- 4354486
TI  - [Nonchromaffin paraganglioma of the orbit].

PMID- 4354487
TI  - [Blood hydrocortisone and corticosterone level in dogs with experimental
      tuberculosis].

PMID- 4354488
TI  - Computerized axial tomography of the head: the EMI-scanner, a new device for
      direct examination of the brain "in vivo". Special article.

PMID- 4354489
TI  - Intraocular penetration of Ara A and idu-therapeutic implications in clinical
      herpetic uveitis.

PMID- 4354490
TI  - Ophthalmic ointment.

PMID- 4354492
TI  - [A personal case of congenital malformations possibly due to LSD 25. Review of
      the literature].

PMID- 4354491
TI  - Surgery on only-hearing ears.

PMID- 4354493
TI  - [Group dynamics among Biafran refugees].

PMID- 4354494
TI  - [Effect of motor neurons on the functional characteristics of vertebrate skeletal
      muscles (effects of denervation and cross re-innervation)].

PMID- 4354496
TI  - Cochlear summating potentials. Descriptive aspects.

PMID- 4354495
TI  - [Skeletal growth disorders following radiotherapy and their treatment].

PMID- 4354497
TI  - Vestibular disturbances in clinical otosclerosis.

PMID- 4354498
TI  - Cyclic AMP and calcium ions in mechanical and metabolic responses of smooth
      muscles; influence of some hormones and drugs.

PMID- 4354499
TI  - Adrenergic, cholecystokinetic and morphine-induced effects on extra-hepatic
      biliary motility.

PMID- 4354500
TI  - The metabolic role of lecithin: cholesterol acyltransferase: perspectives form
      pathology.

PMID- 4354501
TI  - Lipids in viruses.

PMID- 4354502
TI  - Acute renal failure in obstetric septic shock. Current views on pathogenesis and
      management.

PMID- 4354503
TI  - Detection of a single, metal-independent aminopeptidase activity in polymyxin
      extracts from Escherichia coli B.

PMID- 4354504
TI  - Roentgen diagnosis of naso-pharyngeal masses.

PMID- 4354505
TI  - Chronic marijuana usage and sleep-wakefulness cycles in cats.

PMID- 4354506
TI  - Studies on dream recall in chronic schizophrenic patients after prefrontal
      lobotomy.

PMID- 4354507
TI  - L-dopa and REM sleep in normal and mentally retarded subjects.

PMID- 4354508
TI  - Effects of alpha-methyltyrosine on REM sleep and brain amine levels in the cat.

PMID- 4354509
TI  - A high activity divalent cation ATPase from the distal, caudal epididymis of
      bulls.

PMID- 4354511
TI  - Alkylated pyrimidine derivatives as antiviral agents. 3. Synthesis and antiviral
      effect of 5-ethyluracil nucleosides.

PMID- 4354512
TI  - [Action mechanism of releasing factors].

PMID- 4354510
TI  - Alternate immunoprophylactic and biologic techniques in the control of viral
      respiratory tract diseases.

PMID- 4354513
TI  - [Renin-angiotensin system and vascular sensitivity in hyperthyroidism].

PMID- 4354514
TI  - [Comparative studies of characteristics of cytochrome C preparations].

PMID- 4354515
TI  - [Neurogenic changes of electromyography in the general population].

PMID- 4354516
TI  - Respiratory syncytial and adenovirus infections of the lower respiratory tract in
      infanCY.

PMID- 4354517
TI  - Chronic renal failure.

PMID- 4354518
TI  - [The malignant degeneration of mixed parotid gland tumors].

PMID- 4354519
TI  - [Carcinomas in mixed palatal tumors].

PMID- 4354520
TI  - [Results in the conservative parotidectomy in pleomorphous adenomas--report on
      110 cases].

PMID- 4354521
TI  - [184 cases of mixed tumors of the salivary glands at the Northwest German Dental
      Clinic from 1946-1967].

PMID- 4354522
TI  - [Salivary gland adenomas in the infant].

PMID- 4354523
TI  - [Tumors of aberrant salivary gland tissue].

PMID- 4354524
TI  - [Mixed tumors of the soft tissues of the mouth].

PMID- 4354525
TI  - [Cylindromas of the maxillofacial region].

PMID- 4354526
TI  - [Pathology and therapy of cylindromas].

PMID- 4354528
TI  - [Results of cylindroma therapy].

PMID- 4354527
TI  - [The radical treatment of cylindromas].

PMID- 4354529
TI  - [Cylindromas in the jaw bones].

PMID- 4354530
TI  - [Results of katamnestic studies on 41 cases of cylindroma].

PMID- 4354531
TI  - [Surgical consequences in a cylindroma of the submandibular gland with invasion
      of the common carotid artery].

PMID- 4354532
TI  - [Preliminary results in the study of velocity of the nervous conduction in
      chronic uremia by means of a new electronic apparatus].

PMID- 4354533
TI  - Conversion of angiotensin 1 to angiotensin 2 in the isolated perfused dog lung.

PMID- 4354534
TI  - Starvation and human slow-wave sleep.

PMID- 4354535
TI  - Observations on the growth of varicella-zoster virus in human diploid cells.

PMID- 4354536
TI  - Homogeneous murine myeloma protein-315 and spin-labeled DNP as a model system for
      spin-labeled hapten titration technique and spin immunoassay.

PMID- 4354537
TI  - Radioimmunoelectroosmophoresis, a technique combining immunoelectroosmophoresis
      with autoradiography; applications to virology.

PMID- 4354538
TI  - X-ray of the month.

PMID- 4354539
TI  - [A case of Hb M Saki; diagnosed as Hb M Hyde Park by the use of ESR method].

PMID- 4354540
TI  - [Intravenous inoculation direct challenge method for potency test of Japanese
      encephalitis vaccine on suckling mice].

PMID- 4354541
TI  - [Radioimmunoassay of alpha fetoprotein].

PMID- 4354542
TI  - When should you consider a cortisone prep?

PMID- 4354543
TI  - [Transient(?) pluristimulinic pituitary insufficiency due to synthetic beta 1-24
      corticotropin in a subject with prior serious neonatal brain disease].

PMID- 4354545
TI  - [Vasoactive substance and the lung].

PMID- 4354544
TI  - Effect of catecholamines, histamine and oxyfedrine on isotonic contraction and
      cyclic AMP in the guinea-pig heart.

PMID- 4354546
TI  - [Morphological basis and use in clinical neurology of changes in the rate of
      motor nerve conduction].

PMID- 4354547
TI  - [Hyposecretory myeloma].

PMID- 4354548
TI  - [Prevention of infectious complications of acute leukemias: place of general and
      intestinal antibiotic therapy].

PMID- 4354550
TI  - [3 cases of Schwartz-Bartter syndrome during bronchial cancers observed in a
      department of general medicine in less than one year].

PMID- 4354549
TI  - [Botulism].

PMID- 4354551
TI  - [Existence of false antistreptolysins in leprosy].

PMID- 4354553
TI  - Cross-species transmission of mammalian RNA tumor viruses.

PMID- 4354554
TI  - Methods of differentiation between virulent and attenuated strains of infectious
      canine hepatitis.

PMID- 4354552
TI  - Pseudogout.

PMID- 4354555
TI  - [Activation of Rous virus replication in a naturally resistant human embryonic
      cell culture].

PMID- 4354556
TI  - [Barr's cell nuclear body in the mammary duct epithelium].

PMID- 4354557
TI  - [Gastrin: recent physiopathological advances].

PMID- 4354558
TI  - [NDPase and TPPase in normal and pathological human glia cells].

PMID- 4354559
TI  - Structure-activity relationships for inhibitors of phosphodiesterase from
      erythrocytes and other tissues.

PMID- 4354560
TI  - Response of the eye to a flash of light.

PMID- 4354561
TI  - Absent posterior arch of the atlas.

PMID- 4354563
TI  - [Parotid mixed tumor-epithelioma association. Apropos of 23 cases].

PMID- 4354562
TI  - [Myoepithelial cell breast tumor. Ultrastructural study].

PMID- 4354565
TI  - Rat uterine contractility and the activities of uterine adenyl cyclase and
      phosphodiesterase during the estrus cycle.

PMID- 4354564
TI  - Purine nucleotide synthesis in lymphoblasts cultured from normal subjects and a
      patient with Lesch-Nyhan syndrome.

PMID- 4354566
TI  - Roy Hertz (1909- ).

PMID- 4354567
TI  - Chemotherapy of choriocarcinoma and related trophoblastic tumors in women.

PMID- 4354568
TI  - [Titration in nonaqueous media. IV. Analytic behavior of dosulepin chloride
      during titration using perchloric acid in acetic acid medium and its anhydride].

PMID- 4354569
TI  - [Alpha-fetoprotein].

PMID- 4354570
TI  - [Cyclic AMP].

PMID- 4354571
TI  - [Receptor of gonadotropin].

PMID- 4354572
TI  - [Basedow's disease and cyclic AMP].

PMID- 4354573
TI  - The kinetics of transmitter release in myasthenia gravis. 3. An
      electrophysiological analysis of the release of transmitter.

PMID- 4354574
TI  - Muscle tone abnormality and tonic vibration reflex (TVR).

PMID- 4354575
TI  - Modulation of adenyl cyclase action in toad bladder by chlorpropamide: antagonism
      to prostaglandin E.

PMID- 4354576
TI  - The action of reserpine on teleost melanophores.

PMID- 4354577
TI  - Studies on the bradycardia induced by (-)- -trans-tetrahydrocannabinol in
      anesthetized dogs.

PMID- 4354579
TI  - Acute effects of morphine on dopamine synthesis and release and tyrosine
      metabolism in the rat striatum.

PMID- 4354578
TI  - Interaction of vasoactive agents and micro-emboli on the pulmonary circulation.

PMID- 4354580
TI  - [The use of the reaction of the formation of metallic hydroxamic acids and
      hydroxamates in the analysis of drugs and biologically active substances].

PMID- 4354581
TI  - [Benign tumors of the esophagus (review of the literature)].

PMID- 4354582
TI  - [Clinical aspects of cytomegaly].

PMID- 4354583
TI  - [Epidemiology, virology and virological diagnosis of cytomegaly].

PMID- 4354584
TI  - Overview of gestational trophoblastic neoplasia.

PMID- 4354586
TI  - Multiplication, O2 consumption and cytochrome oxidase activity of a cold-adapted
      L cell line.

PMID- 4354585
TI  - Cardiogenic shock. Recent advances in pharmacologic management. II.

PMID- 4354587
TI  - [Occurrence of alpha-fetoprotein in various forms of hepatitis, cirrhosis and
      primary hepatic cancer].

PMID- 4354588
TI  - [Advances in endocrinology. Hormonal regulation of the synthesis of biologically
      active vitamin D metabolites. (Experimentation and clinical problems)].

PMID- 4354589
TI  - [Encephalomyeloneuropathy following carbon monoxide poisoning].

PMID- 4354590
TI  - [Value of angiography in the exploration of bronchial or bronchiolar tumors].

PMID- 4354591
TI  - Synthesis of 2-hydroxy-ethynylestradiol and 4-hydroxy-ethynylestradiol.

PMID- 4354592
TI  - [Ulcerative colitis. Principles and therapy].

PMID- 4354593
TI  - The relationship between the viruses causing hepatitis and autoimmunity in liver
      disease.

PMID- 4354595
TI  - [Histochemical studies of the urinary tract in guinea pigs infected with T.
      vaginalis].

PMID- 4354596
TI  - Syndactyly in a German shepherd dog.

PMID- 4354594
TI  - [3-dimensional electron microscopy of biological macromolecules].

PMID- 4354597
TI  - Intranuclear fibrillar bundles in functioning beta-cell adenoma of pancreas.

PMID- 4354598
TI  - Effect of cyclic 3'-5'-adenosine monophosphate and theophylline on renal
      function.

PMID- 4354599
TI  - Reinvestigation of the anaerobic glycolytic potential of the regenerating rat
      liver.

PMID- 4354601
TI  - Isoelectric focusing of human fetoprotein: an aid in purification and
      characterization of microheterogeneity.

PMID- 4354600
TI  - A review of clinical applications and methods for cholinesterase.

PMID- 4354602
TI  - [Mesotheliomas in Syrian hamster. I. Macroscopical, histological, and
      electronmicroscopical observations].

PMID- 4354603
TI  - Yeast inorganic pyrophosphatase. II. Magnetic resonance and steady-state kinetic
      studies of metal ion and pyrophosphate analog binding.

PMID- 4354604
TI  - Circular dichroism studies of the conformation of synthetic peptides in the
      carboxyl-terminal region of cytochrome c.

PMID- 4354605
TI  - Proton magnetic resonance studies of horse cytochrome c.

PMID- 4354606
TI  - A molecular weight determination of the 16S ribosomal ribonucleic acid from
      Escherichia coli.

PMID- 4354607
TI  - Effects of deoxyribonucleic acid and histone on the number and length of chains
      of poly(adenosine diphosphate-ribose).

PMID- 4354608
TI  - Magnetic resonance studies of substrate and inhibitor binding to porcine muscle
      adenylate kinase.

PMID- 4354609
TI  - Kinetic effects of inorganic pyrophosphate analogs on several inorganic
      pyrophosphate hydrolyzing enzymes.

PMID- 4354610
TI  - [Determination of cyclic AMP by binding competition: application to biologic
      fluids].

PMID- 4354611
TI  - [Comparison of partial pressure of 0-2 and CO-2 and 0-2 consumption in 3
      experimental ascitic tumors].

PMID- 4354612
TI  - Estradiol receptors in benign and malignant disease of the breast.

PMID- 4354613
TI  - Free radicals and neoplasia--some experimental findings and some possible
      implications.

PMID- 4354616
TI  - Studies on the bacteriophage MS2. An internal nucleotide fragment resembling some
      ribosomal binding sites.

PMID- 4354614
TI  - Calcium and gastrointestinal secretion.

PMID- 4354617
TI  - Oxidative phosphorylation in bacteria which contain different cytochrome
      oxidases.

PMID- 4354619
TI  - The effect of fluoride on the spectral and catalytic properties of the three
      copper-containing oxidases.

PMID- 4354620
TI  - Microbial assimilation of methanol. The ethanol- and methanol-oxidizing enzymes
      of the yeast Candida boidinii.

PMID- 4354618
TI  - Studies on the mechanism of the oxygen-induced synthesis of cytochrome oxidase in
      yeast. Specific effects of benzimidazole on cytochrome-oxidase anabolism.

PMID- 4354622
TI  - Solubility requirements for cholesterol esters in human plasma: role of high
      density lipoprotein protein and phospholipids.

PMID- 4354621
TI  - Subcellular location of superoxide dismutase in spinach leaves and preparation
      and properties of crystalline spinach superoxide dismutase.

PMID- 4354623
TI  - [Autonomic nervous system and secretion of insulin. II. Effect of adrenergic
      blockaders on the insulin secretion in response to tolbutamide].

PMID- 4354624
TI  - Zollinger-Ellison syndrome.

PMID- 4354625
TI  - An enzyme variation in a case of congenital methemoglobinemia.

PMID- 4354626
TI  - Infective agents in the causation of Hodgkin's disease. A review of the
      epidemiological evidence.

PMID- 4354628
TI  - Afferent lung denervation by brief inhalation of steam.

PMID- 4354627
TI  - [Change in the level of free radicals and the activity of certain enzymes in the
      mammary gland tissues of mice during the development of spontaneous cancer].

PMID- 4354629
TI  - Isomer subfractionation effects in the study of longer chain monoethylene fatty
      acids in hydrogenated oils.

PMID- 4354631
TI  - Note on the activity of angiotensinase in exercise proteinuria.

PMID- 4354630
TI  - The component triglycerides of rat adipose tissue. I. As studied after
      fractionation into classes by silver ion-thin layer chromatography.

PMID- 4354632
TI  - Electron microscope studies on aldehyde-fixed, unstained microbial cells.

PMID- 4354633
TI  - Whipple's disease.

PMID- 4354634
TI  - Histochemical studies on thyroid adenoma built of C cells.

PMID- 4354635
TI  - The mode of action and clinical use of spirolactones.

PMID- 4354636
TI  - [Current views on the etiology, pathogenesis and epidemiology of whooping cough].

PMID- 4354637
TI  - Studies on the antilipolytic effect of adenosine and related compounds in
      isolated fat cells.

PMID- 4354638
TI  - Frequency dependent decrease of quantal content in a drug-treated neuromuscular
      junction.

PMID- 4354639
TI  - Effects of antilipolytic drugs on cyclic 3',5'-AMP dependent protein kinase.

PMID- 4354640
TI  - Michaelis-Menten kinetics of secretion of sympathetic neurotransmitter as a
      function of external calcium: effect of graded alpha adrenoceptor blockade.

PMID- 4354641
TI  - Micropuncture investigations on the effect of angiotensin on the inorganic
      phosphate reabsorption in the proximal tubule of the rat.

PMID- 4354643
TI  - Microphysiology of vertebrate neuromuscular transmission.

PMID- 4354642
TI  - Copper homeostasis in the mammalian system.

PMID- 4354644
TI  - [Primary hyperparathyroidism].

PMID- 4354645
TI  - [Stomatitis in children with influenza, parainfluenza and adenoviral infection].

PMID- 4354646
TI  - [Chemodectoma of carotid paraganglia].

PMID- 4354647
TI  - [RNA content in neurons and their cell satellites in the supraoptic nucleus of
      the rat brain in natural sleep, its REM phase deprivation, and amphetamine
      insomnia].

PMID- 4354648
TI  - [Some new aspects of the renin-angiotensin system].

PMID- 4354650
TI  - [Excretion of cyclic AMP in arterial hypertension].

PMID- 4354649
TI  - [Morphodynamic study on the ontogenesis of the renin-angiotensin system].

PMID- 4354651
TI  - [Effect of glucagon on cholesterol esterification and on blood cholesterol levels
      in normal and hyperlipidemic subjects].

PMID- 4354652
TI  - [Effect of angiotensin II in vitro on RNA, protein, cyclic AMP and aldosterone
      biosynthesis, using a cell suspension system from the zona glomerulosa of the
      adrenals].

PMID- 4354653
TI  - [Changes in regional concentrations of cerebral monoamines induced by
      angiotensin].

PMID- 4354654
TI  - Spontaneous and virus induced transformation in cell culture.

PMID- 4354656
TI  - Brain tumors during the first year of life.

PMID- 4354655
TI  - Tissue response to a single intraperitoneal injection of various substances in
      rats.

PMID- 4354657
TI  - The inhibitory effect of diethylaminoethyl diphenylvalerate (SKF 525-A) on
      glucuronidation by cultures of rat hepatoma cells.

PMID- 4354659
TI  - Disorders due to enzyme defects in the red blood cell.

PMID- 4354660
TI  - Biology of the trophoblast.

PMID- 4354661
TI  - Tumours of the central nervous system in Zambia.

PMID- 4354662
TI  - Prostaglandins and asthma.

PMID- 4354663
TI  - Enterotoxic diarrheal syndromes.

PMID- 4354664
TI  - Insulin receptors.

PMID- 4354665
TI  - Review of reviews.

PMID- 4354667
TI  - [The cornea (inflammatory keratitis)].

PMID- 4354666
TI  - Experimental studies on cobalt cardiopathy.

PMID- 4354669
TI  - [Incompatibility groups of plasmids confering resistance to gentamicin].

PMID- 4354668
TI  - Cytology of the corpus luteum.

PMID- 4354671
TI  - Some interface phenomena in parasitic protozoa and platyhelminths.

PMID- 4354672
TI  - [Cerebral angiography and cerebral death].

PMID- 4354670
TI  - The mystique of the herpesviruses.
AB  - Probing the biologic mystique of the herpesvirus family, we find elements of
      antigenic similarity, the capacity of virions to persist within our cells in
      complete form, and the potential at some later time for these virions to undergo
      renewed replication. A venereal mode of transmission from one host to another may
      be characteristic of some of these viruses. Similar patterns of illness may be
      produced by several of the herpesviruses. Within the cellular framework of
      inflammation and necrosis which infective virus may evoke in the host, there may
      also reside the capability of neoplastic transformation.

PMID- 4354673
TI  - [The "empty sella"--a problem in differential diagnosis].

PMID- 4354674
TI  - [The diagnosis of arachnoid cysts by peneumo-encephalography].

PMID- 4354676
TI  - [The value of scintigraphy in the diagnosis of C.S.F. fistulae].

PMID- 4354675
TI  - [Duplication of the vertebral artery].

PMID- 4354677
TI  - [Endo-lumbar radiculography during myelography].

PMID- 4354678
TI  - [Can angiografin be used for lumbar myelography?].

PMID- 4354679
TI  - [The value of various projections for the evaluation of arterio-sclerotic changes
      in the abdominal aorta and iliac arteries].

PMID- 4354680
TI  - [Angiography of the feet].

PMID- 4354681
TI  - [Post-operative angiography for the evaluation of reconstructive surgery of the
      lower limb vessels].

PMID- 4354682
TI  - [Aspects of transluminal catheter-recanalisation and the treatment of
      recurrences].

PMID- 4354683
TI  - [Coarctation of the abdominal aorta combined with stenoses of the origins of the
      coeliac trunk, superior mesenteric artery and both renal arteries].

PMID- 4354684
TI  - [The angiographic examination of hepatic vessels in chronic hepatitis].

PMID- 4354686
TI  - [Radiation dose received by personnel during radiological diagnostic procedures;
      current criteria for its evaluation].

PMID- 4354685
TI  - A clinical comparison between monochrome color film and black and white RP-film
      as a universal x-ray film. A preliminary report.

PMID- 4354687
TI  - [Posttraumatic epidural hematoma with arteriovenous fistula of medial meningeal
      artery].

PMID- 4354688
TI  - [Bilateral carotis-sinus-cavernosus fistula].

PMID- 4354689
TI  - [Extraventricular and extramedullary metastases of a cerebellar medulloblastoma].

PMID- 4354690
TI  - [Myeloscintigraphy and pantopaque myelography in traumatic cervical root
      extraction--diagnostic contribution].

PMID- 4354692
TI  - An electron microscopic study of synaptic organization in the medial superior
      olive of normal and experimental chinchillas.

PMID- 4354693
TI  - Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral
      agents. 1. Bisalkamine esters of fluorenone-, fluorenol-, and
      fluorenedicarboxylic acids.

PMID- 4354691
TI  - [Professor Dr. Erich Zdansky's 80th anniversary].

PMID- 4354694
TI  - The N6-(dimethylamino)methylene derivative of 9-beta-D-arabinofuranosyladenine as
      an antiviral agent.

PMID- 4354697
TI  - Regeneration of the endometrium in rabbits after curettage. II. Pretreatment with
      progesterone.

PMID- 4354696
TI  - Regeneration of the endometrium in rabbits after curettage. I. Pretreatment with
      estrogens.

PMID- 4354695
TI  - Phenocopies.

PMID- 4354698
TI  - [Antibacterial activities of lincomycin and clindamycin against anerobic
      bacteria].

PMID- 4354700
TI  - Malignant uterine mesotheliomas in squirrel monkeys following diethylstilbestrol
      administration.

PMID- 4354701
TI  - Use of neotropical rodents in protein efficiency studies.

PMID- 4354702
TI  - An automatic data processing system for long-term toxicological study utilizing
      the beagle dog.

PMID- 4354703
TI  - Serum thyroxine levels in the perinatal guinea pig (Cavia porcellus).

PMID- 4354705
TI  - Stability of resistance-susceptibility characteristics in 2 inbred mouse strains.

PMID- 4354704
TI  - Tuberculin testing in rhesus monkeys (Macaca mulatta): a comparative study using
      experimentally sensitized animals.

PMID- 4354706
TI  - Characterization of a fibroma virus isolated from naturally-occurring skin tumors
      in domestic rabbits.

PMID- 4354699
TI  - [Ectopic paraneoplastic endocrinopathies associated with water-electrolyte
      balance disorders].

PMID- 4354707
TI  - Neoplasms and proliferative lesions in 1065 nonhuman primate necropsies.

PMID- 4354708
TI  - Edentate diets. I. Armadillos.

PMID- 4354709
TI  - Edentate diets. II. Two-toed sloths.

PMID- 4354710
TI  - Repair of a mandibular fracture in an irradiated monkey using intraoral
      immobilization and intraosseous metal mesh fixation.

PMID- 4354711
TI  - A vacuum-assisted technic for repetitive blood sampling in the rat.

PMID- 4354712
TI  - Technic for collecting blood from neonatal rats.

PMID- 4354713
TI  - The use of succinylcholine in the handling and restraint of rhesus monkeys
      (Macaca mulatta).

PMID- 4354714
TI  - Spontaneous Lancefield group G streptococcal infection in a random source cat
      colony.

PMID- 4354716
TI  - A simplified technic for preparing sterile chicken serum.

PMID- 4354715
TI  - A clinical laboratory study of conditioned mongrel dogs and Laborador retrievers.

PMID- 4354717
TI  - Comparative organ weights for 8 standardized wild rodent species.

PMID- 4354719
TI  - A case of spontaneous congenital pyloric stenosis in a rabbit.

PMID- 4354718
TI  - Baseline blood determinations of the Taiwan macaque (Macaca cyclopis).

PMID- 4354720
TI  - Long-term rabbit restraint--a simple method.

PMID- 4354721
TI  - [The state of and prospects for elaboration of methods for early diagnosis of
      radiation disease].

PMID- 4354722
TI  - Enzyme induction by viruses.

PMID- 4354723
TI  - [Diagnosis of brain tumors. Accuracy of ambulatory feasible supplemental
      studies].

PMID- 4354724
TI  - [Vital cytology of mammary cancer].

PMID- 4354726
TI  - Neurotropic viruses and the developing brain.

PMID- 4354727
TI  - Purification of 9 -tetrahydrocannabinol, an active constituent of marihuana, by
      accelerated microparticulate gel chromatography.

PMID- 4354728
TI  - Electroencephalography.

PMID- 4354729
TI  - [Specificity of enzymatic reactions].

PMID- 4354732
TI  - Adrenal response to synthetic adrenocorticotrophic hormone during pregnancy and
      after delivery, with special reference to pre-eclamptic and hypertensive
      pregnancy.

PMID- 4354730
TI  - [Contribution of hemodynamic studies to the diagnosis and treatment of arterial
      hypertension].

PMID- 4354731
TI  - On the pathogensis of renovascular hypertension.

PMID- 4354733
TI  - Long-chain acyl-CoA synthetase activity in blood platelets and some human
      tissues.

PMID- 4354734
TI  - Bluetongue virus.

PMID- 4354735
TI  - [Marek's disease].

PMID- 4354736
TI  - Biological significance of molecular chirality in energy balance and metabolism.

PMID- 4354737
TI  - The results of prophylaxis of endemic cretinism with iodized oil in rural Andean
      Ecuador.

PMID- 4354738
TI  - Increased aldosterone secretion during sodium depletion with inhibition of renin
      release.

PMID- 4354739
TI  - Some parameters relevant to affinity chromatography on immobilized nucleotides.
AB  - 1. The suitability of cellulose and Sepharose as supports for affinity
      chromatography of two groups of cofactor-linked enzymes, dehydrogenases and
      kinases, was examined. Sepharose was found to be superior. 2. The selective
      capacities of the columns were measured by frontal analysis and are discussed in
      relation to the nucleotide contents. 3. The effect of various concentrations of
      enzyme and of non-specific protein on the performance of the affinity columns,
      and the effects of equilibration time, flow rate, sample volume and dilution of
      the nucleotide were examined. 4. The effect of interposing polymethylene and
      polyglycine extension arms between the matrix backbone and the nucleotide was
      investigated for several cofactor-dependent enzymes. Maximum binding was observed
      with an extension arm 0.8-1nm long.

PMID- 4354740
TI  - Affinity chromatography of lactate dehydrogenase on immobilized nucleotides.
AB  - The interaction of two isoenzymes of lactate dehydrogenase from pig heart muscle
      (H(4)) and rabbit skeletal muscle (M(4)), with immobilized nucleotides was
      examined: the effects of pH and temperature on the binding of lactate
      dehydrogenase were studied with immobilized NAD(+) matrices. The influence of
      substrate, product and sulphite on the binding of heart muscle lactate
      dehydrogenase to immobilized NAD(+) was investigated. The interaction of both
      lactate dehydrogenase isoenzymes with immobilized pyridine and adenine
      nucleotides and their derivatives were measured. The effects of these parameters
      on the interaction of lactate dehydrogenase with immobilized nucleotides were
      correlated with the known kinetic and molecular properties of the enzymes in free
      solution.

PMID- 4354742
TI  - Adenosine 3':5'-cyclic monophosphate-binding protein from the cellular slime
      mould Dictyostelium discoideum.
AB  - During the differentiation of myxamoebae of Dictyostelium discoideum strain Ax-2
      grown in axenic medium there is a seven- to ten-fold increase in the specific
      activity of cyclic AMP-binding protein(s). Evidence is presented for the belief
      that cyclic AMP phosphodiesterase and cyclic AMP-binding protein are distinct
      molecular species.

PMID- 4354741
TI  - The mechanism of inhibition of rat liver tryptophan pyrrolase activity by 4
      hydroxypyrazolo(3,4-d)pyrimidine (Allopurinol).
AB  - 1. Allopurinol (4-hydroxypyrazolo[3,4-d]pyrimidine) selectively inhibits the
      apotryptophan pyrrolase activity in homogenates of rat liver in vitro and after
      intraperitoneal administration. The inhibition is abolished by an excess of
      haematin. The allopurinol metabolite alloxanthine has no effect on the pyrrolase
      activity in vitro or after administration. Allopurinol also inhibits the
      activation of the enzyme in vitro by ascorbate, ethanol plus NAD(+), NADH,
      hypoxanthine or xanthine. It is suggested that these agents cause the conversion
      of a latent form of the pyrrolase into the apoenzyme, and that xanthine oxidase
      is not involved in this process. 2. The raised total pyrrolase activity observed
      after the administration of cortisol, cyclic AMP, tryptophan, salicylate or
      ethanol is lowered by allopurinol in vitro to the corresponding holoenzyme
      values. A similar effect is observed when allopurinol is administered shortly
      before cortisol or cyclic AMP. Pretreatment of rats with allopurinol completely
      prevents the enhancement of the pyrrolase activities by tryptophan, salicylate or
      ethanol. 3. It is suggested that allopurinol inhibits rat liver tryptophan
      pyrrolase activity in vitro and after administration by preventing the
      conjugation of the apoenzyme with its haem activator. The possible usefulness of
      combined allopurinol-tryptophan therapy of affective disorders is discussed.

PMID- 4354743
TI  - Inosine 5'-monophosphate dehydrogenase of Escherichia coli K12: the nature of the
      inhibition by guanosine 5'-monophosphate.
AB  - When IMP is the variable substrate, IMP dehydrogenase (EC 1.2.1.14) gives non
      linear Lineweaver-Burk plots in the presence of GMP. At 0.1mm-GMP the Hill
      coefficient n=1.15 and at 0.2mm-GMP n=1.34. In the absence of GMP n=1.0. The fact
      that n exceeds 1.0 in the presence of GMP indicates that the enzyme possesses
      regulatory (allosteric) properties. The inhibition by GMP is competitive with
      respect to IMP and non-competitive with respect to NAD(+).

PMID- 4354744
TI  - Infection with E.B. virus.

PMID- 4354747
TI  - Late clinical and roentgen observations following Thorotrast administration.

PMID- 4354746
TI  - The radiological and scintigraphic investigation of spontaneous hypoglycaemia.

PMID- 4354748
TI  - [Resistance of German chicken lines against avian myeloblastosis virus (AMV)].

PMID- 4354749
TI  - Sensitivity to mutagens of Rumex acetosa chromosomes.

PMID- 4354750
TI  - Enhancement of ethylemethane sulfunate-induced frequency in Drosophila by
      dimethyl sulphoxide.

PMID- 4354751
TI  - Inhibition of angiotensin-coverting enzyme by analogs of peptides from Bothrops
      jararaca venom.

PMID- 4354752
TI  - Isolation of different thermophilic enzymes from Bacillus stearothermophilus.

PMID- 4354753
TI  - Phosphatases. IX. Differences in sialic acid content of rat liver alkaline
      phosphatase isoenzymes.

PMID- 4354754
TI  - Enzyme-polymer adducts of aldolase, glyceraldehydephosphate dehydrogenase, and
      fructosediphosphatase.

PMID- 4354756
TI  - The lung in relation to vasoactive hormones.

PMID- 4354757
TI  - Digestive physiology with reference to enzymes in the alimentary canal of
      coridius janus Fabr. (Heteroptera: Dinidoridae).

PMID- 4354755
TI  - Effect of chemical sympathectomy on pressor responses to norepinephrine,
      angiotensin and tyramine.

PMID- 4354759
TI  - Observations in an aftercare group.

PMID- 4354758
TI  - Hormone: receptor interactions. Biological activities of (phenylalanine,
      norvaline)-adrenocorticotropin-(1-24)-tetrakosipeptide and its 4,5-dehydro-4,5
      ditritio-norvaline analogue in isolated rat lipocytes and adrenal cortex cells:
      lipolysis, corticosterone and cyclic adenosine-3',5'-monophosphate production.

PMID- 4354760
TI  - Absorption of fortification iron by the rat: comparison of type and level of iron
      incorporated into mixed grain cereal.

PMID- 4354761
TI  - Simultaneous quantitative comparison of the optical changes at 700 nm (p700) and
      electron spin resonance signals in system I of green plant photosynthesis.

PMID- 4354762
TI  - Myasthenia gravis.

PMID- 4354763
TI  - Chloroethyl-cyclohexyl-nitrosourea (CCNU) in the treatment of malignant brain
      tumors.

PMID- 4354764
TI  - Postoperative intracavitary chemotherapy of malignant gliomas. A preliminary
      study using methotrexate.

PMID- 4354765
TI  - Ventriculoatrial shunt blockage by previous positive contrast ventriculography.

PMID- 4354766
TI  - Analysis of Mauthner cell responses to iontophoretically delivered pulses of
      GABA, glycine and L-glutamate.
AB  - 1. The intracellularly recorded responses of goldfish Mauthner neurones to
      iontophoretically applied pulses of amino acids have been analysed: their time
      courses have been compared with each other, and with those predicted from
      diffusion theory.2. The rise time of the response to GABA is slower than that to
      glycine or L-glutamate. The response curves of the latter substances were very
      similar, and unlike that of GABA were markedly affected by increasing the
      distance of pipette-tip from the membrane. The results suggest that the time
      course of the responses to glycine and L-glutamate are determined mainly by free
      diffusion in the brain tissue (at least within about 200 mum of the cell), while
      that to GABA must be rate-limited by other factors, e.g. drug-receptor activation
      time.3. The possibility that the responses are influenced by some desensitizing
      process was investigated by applying a second (test) drug pulse during the
      response to a prior conditioning one. In the case of glycine and of L-glutamate
      there was no attenuation of the response to a second pulse at any time. With
      GABA, however, the second response was reduced during the period of the
      conditioning response; the reduction was progressively less marked the later the
      test pulse occurred. A similar effect with GABA was seen when glycine was used as
      the test pulse. The responses to long-maintained drug pulses also indicated that
      for GABA, but not for glycine or glutamate, there seems to be some desensitizing
      process present.4. Calculated time courses of responses to brief pulses of
      glycine and of L-glutamate (based upon diffusion theory) differed somewhat from
      the observed curves, largely during the falling phase. However, when the
      calculations were based upon second-order reactions (two molecules of drug per
      receptor) the diffusion model gave results very like the observed ones.5.
      Possible implications of these results for the role these three amino acids may
      have as neuro-transmitters are mentioned.

PMID- 4354767
TI  - Relationship of end-plate morphology to junctional chemosensitivity.

PMID- 4354769
TI  - The effect of nicotinic acid and alloxan on the secretion of electrolytes and
      amylase by the isolated saline perfused pancreas of the cat.

PMID- 4354768
TI  - Spontaneous quantal transmitter release: a statistical analysis and some
      implications.
AB  - 1. Miniature end-plate potentials (m.e.p.p.s) were intra- and extracellularly
      recorded from neuromuscular junctions in rat phrenic nerve-diaphragm preparations
      in vitro.2. Statistical analysis of the intervals between m.e.p.p.s showed that
      when the mean number of events in time t was plotted as a function of the
      variance of the events in time t there was a significant deviation from the
      straight line relationship expected for a Poisson process. Computer simulation
      showed that this deviation is explicable if release was generated by the random
      phasing of the activity of a number of releasing sites.3. There was no indication
      that release of one quantum influences the probability of release of remaining
      quanta (drag, clustering). It is suggested that m.e.p.p.s whose amplitude is
      larger than the mode result from the release of the contents of vesicles whose
      volume is also supramodal.4. The effects of depolarization of nerve terminals
      upon the variance-mean curve suggest an increase in the activity of sites rather
      than an increase in their number.5. Statistical analysis indicated at least 200
      +/- 100 (mean +/- 1 S.E.) releasing sites. This number is of the same order as
      the number of sites of vesicle aggregation and presynaptic membrane density seen
      in electron micrographs of nerve terminals of this preparation.

PMID- 4354771
TI  - Small cell carcinoma of the lung. Clinicopathological studies.

PMID- 4354770
TI  - The membrane effects, and sensitivity to strychnine, of neural inhibition of the
      Mauthner cell, and its inhibition by glycine and GABA.
AB  - 1. Anionic conductance changes in Mauthner neurones of goldfish were measured
      during synaptically evoked inhibition and inhibition caused by iontophoretic
      application of the putative inhibitory transmitters glycine and gamma
      aminobutyric acid (GABA).2. The effects of either amino acid were
      indistinguishable from those of the neural inhibitory transmitter(s). The
      membrane permeability during the neural or drug response was increased to Br(-),
      Cl(-), I(-), SCN(-), NO(3) (-), ClO(3) (-), and formate (HCOO(-)), but not to
      HCO(3) (-), BrO(3) (-), IO(3) (-), SO(4) (-), HPO(4) (-), H(2)PO(4) (-), acetate
      and citrate.3. Strychnine was injected intramuscularly, iontophoretically, or
      applied topically to the exposed brain in order to compare quantitatively its
      ability to prevent inhibition evoked by synaptic activation and by
      pharmacological means. Inhibitions were measured by the increase in membrane
      conductance.4. Strychnine, at concentrations just adequate to block completely
      the late collateral inhibition (LCI) and crossed VIII nerve inhibition, had
      little effect on the pharmacological inhibition caused by glycine, and sometimes
      there was no detectable effect at all. In one experiment even a local
      iontophoretic application of strychnine in a sufficient dose to diffuse over the
      cell and block the LCI almost completely, merely halved the effect of a small
      dose of glycine applied to the same localized region of the membrane.5. Higher
      concentrations of strychnine than those necessary to block synaptically evoked
      inhibition would reduce the effect of glycine but not that of GABA. The evidence
      indicated that any apparent effect of strychnine upon GABA could be explained by
      displacement of the GABA-containing iontophoretic pipette.6. The glycine-blocking
      action of iontophoretic pulses of strychnine was of relatively very slow onset
      and long duration compared to the effects of pulses of glycine and GABA.7. These
      findings can be interpreted as either (1) strychnine has a presynaptic action,
      preventing the release of inhibitory neurotransmitter, in addition to its less
      potent post-synaptic one in blocking pharmacological inhibition, or (2)
      strychnine acts entirely post-synaptically, but the physiological transmitter
      action differs from that of glycine and GABA in being considerably more sensitive
      to strychnine antagonism. In either case, the use of strychnine as evidence for
      the claim that glycine is an inhibitory neurotransmitter at the Mauthner cell is
      questionable.

PMID- 4354772
TI  - Correlation of the clinical response to ACTH treatment with the endocrine status
      in myasthenia gravis.

PMID- 4354773
TI  - Primary mucinous adenocarcinoma of the urinary bladder.

PMID- 4354774
TI  - [Morphologic analysis of 1,356 cases of stomach cancer].

PMID- 4354775
TI  - Buoyant densities of mitochondrial DNA from tumour and normal tissues.

PMID- 4354776
TI  - [Leading criteria of reticulocyte maturation. II. Behavior of cytochrome oxidase
      and of the respiratory chain inhibition agent F in reticulocyte maturation].

PMID- 4354777
TI  - Beclomethasone aerosol in childhood asthma.

PMID- 4354778
TI  - Beclomethasone dipropionate aerosol in childhood asthma.

PMID- 4354779
TI  - Control of fetal lung development in the rabbit.

PMID- 4354781
TI  - Serological studies in asymptomatic congenital cytomegalovirus infection.

PMID- 4354780
TI  - Effect of human growth hormone treatment on adipose tissue in children.

PMID- 4354782
TI  - [Esophageal lesions in neonatal herpes].

PMID- 4354783
TI  - Action of propranolol on lipolysis induced by catecholamine, dibutyryl cyclic AMP
      and serum.

PMID- 4354784
TI  - Effect of intracellular accumulation of inert carbon particles on the cytochromes
      P-450 and b5 levels of rat liver microsomes.

PMID- 4354785
TI  - Effects of sodium salicylate and acetylsalicylic acid on cyclic 3',5'-AMP
      dependent protein kinase.

PMID- 4354786
TI  - Cytochrome c stimulated oxidation of ethanol by liver mitochondria.

PMID- 4354787
TI  - Selective inhibition of nicotinamide adenine dinucleotide dependent oxidations by
      piperazinothioureas.

PMID- 4354788
TI  - Comparative study of cytochromes between virus-transformed and untransformed
      cells.

PMID- 4354790
TI  - Energy conservation capacity and morphological integrity of mitochondria in
      hypotonically treated rabbit epididymal spermatozoa.

PMID- 4354789
TI  - Studies on the activation of purified mitochondrial ATPase by phospholipids.

PMID- 4354791
TI  - Low-temperature spectral properties of the respiratory chain cytochromes of
      mitochondria from Crithidia fasciculata.

PMID- 4354792
TI  - Oxidative phosphorylation and effects of aerobic conditions on Rhodopseudomonas
      viridis.

PMID- 4354794
TI  - Pigment content and molar extinction coefficients of photochemical reaction
      centers from Rhodopseudomonas spheroides.

PMID- 4354793
TI  - Cyanide-resistant respiration and a branched cytochrome system in
      Kinetoplastidae.

PMID- 4354795
TI  - The oxidation-reduction potential of membrane-bound chloroplast plastocyanin and
      cytochrome f.

PMID- 4354796
TI  - Evidence for the identity of P430 of Photosystem I and chloroplast-bound iron
      sulfur protein.

PMID- 4354797
TI  - Anion-exchange chromatography on reversed-phase columns: isolation and assay of
      nucleosides, nucleotides, and oligonucleotides from nucleic acids and from
      cytoplasm.

PMID- 4354798
TI  - Purine nucleotide biosynthesis in gastrointestinal mucosa.

PMID- 4354799
TI  - Interaction between picrotoxin and 5-hydroxytryptamine in the superior cervical
      ganglion of the cat.
AB  - 1. Electrophysiological techniques were utilized to study the actions of 5
      hydroxytryptamine (5-HT) and picrotoxin on the superior cervical ganglion of the
      cat.2. The intra-arterial administration of 5-HT to the ganglion elicited both
      depressant and excitatory actions. In low doses (0.01-0.5 mug) the amine produced
      a depression of ganglionic transmission. In larger doses (2-50 mug) it produced
      an excitation of ganglion cells (early discharge) and an initial enhancement of
      transmission, which was followed by depression. Picrotoxin (25-500 mug, i.a.)
      blocked the initial excitatory effects of 5-HT but did not block the depression.
      Picrotoxin did not antagonize the excitatory actions of injected cholinomimetic
      agents or potassium chloride.3. In ganglia conditioned by repetitive stimulation
      of the preganglionic nerve (30 Hz for 30 s) 5-HT also elicited a late-occurring
      and very prolonged discharge on certain postganglionic nerves (;spinal') but not
      on others (external carotid). The late discharge was only partially depressed by
      picrotoxin.4. Recordings from the surface of the superior cervical ganglion
      revealed that 5-HT produced three types of ganglionic potentials: (1) an initial
      transient depolarization which coincided with the early discharge, (2) a late
      occurring, prolonged depolarization which coincided with the late discharge, and
      (3) a hyperpolarization which in some experiments accompanied the depression of
      transmission. The late depolarization and hyperpolarization were not observed in
      every experiment. Picrotoxin (25-500 mug) blocked the initial depolarization, but
      did not block the late depolarization or the hyperpolarization.5. It is concluded
      the 5-HT can produce three distinct responses in the superior cervical ganglion:
      a depressant effect and two types of excitation. It seems likely that depression
      and excitation occur via the activation of different receptors, since picrotoxin
      selectively blocks the latter. The finding that picrotoxin is a 5-HT antagonist
      in peripheral ganglia raises the possibility that picrotoxin might also influence
      tryptaminergic mechanisms in the central nervous system.

PMID- 4354801
TI  - The effect of glibenclamide on two enzymes important in gluconeogenesis.

PMID- 4354802
TI  - Potentiation by angiotensin II of noradrenaline-induced contractions of a rabbit
      isolated thoracic aorta.

PMID- 4354800
TI  - Characterization of angiotensin receptors in vascular and intestinal smooth
      muscles.
AB  - 1. A series of analogues of angiotensin II (AT(II)) has been used in the present
      experiments to characterize receptors for AT(II) in intestinal (rat stomach
      strip, rat colon) and vascular (rabbit aorta) smooth muscles. Two types of
      compounds have been chosen: (a) agonists with reduced potency, in which 4-Tyr, 6
      His or 7-Pro had been substituted with L-Ala or with Gly and 1-amino-cyclopentane
      carboxylic acid (Acpc) and (b) competitive antagonists (8-Gly-AT(II), 8-Leu
      AT(II)).2. Replacement of 4-Tyr, 6-His and 7-Pro with L-Ala decreases the
      potency, but does not influence the maximum effect of the analogue, while
      substitution of the same residue with Gly and Acpc reduces both potency and
      maximum effect.3. Compounds showing full size maximum responses were chosen to
      establish the following order of potency on the three preparations: AT(II)>4-Phe
      AT(II)>7-Ala-AT(II)>6-Ala-AT(II)>4-Ala-AT(II).4. The four derivatives of AT(II)
      were completely inactive on tissues desensitized with AT(II). The responses to 5
      hydroxytryptamine, acetylcholine and noradrenaline were not significantly
      modified, except for the rat colon.5. pA(2) values for the two competitive
      antagonists against AT(II) and 4-Phe-AT(II) were estimated in the three
      preparations by the use of the cascade superfusion technique. For comparison,
      pA(2) values were also estimated in rat stomach strips and rabbit aortas
      suspended in a normal organ bath, according to the method of Schild (1947). The
      similarities of the pA(2) values obtained in two series of experiments indicate
      that (a) the cascade superfusion technique is suitable for this type of study and
      (b) the receptor for AT(II) in the three tissues may be the same.6. It is
      suggested that receptors for AT(II) in intestinal and vascular smooth muscles may
      be the same, because (a) the order of potency of various agonists follows the
      same pattern, (b) the agonists are inactive on tissues desensitized with AT(II),
      (c) pA(2) values for competitive antagonists are similar in the three
      preparations.

PMID- 4354803
TI  - Atropine sensitivity of transmission and facilitation in the rabbit superior
      cervical ganglion.

PMID- 4354804
TI  - Drugs influencing plasma and brain tryptophan.

PMID- 4354806
TI  - Plasma renin and the antihypertensive effect of 1-Sar-8-Ala-angiotensin II.

PMID- 4354805
TI  - In vivo changes in the concentration of cerebral cyclic AMP, phosphorylase a and
      glycogen induced by biogenic amines.

PMID- 4354807
TI  - Effect of propranolol and theophylline on renin release caused by furosemide in
      the cat.

PMID- 4354808
TI  - Inhibition by SQ 20881 of vasopressor response to angiotensin I in conscious
      animals.

PMID- 4354809
TI  - The effects of theophylline and cyclic AMP on intestinal smooth muscle
      contractions.

PMID- 4354810
TI  - In vitro inhibition by synthetic phospholipids of pressor responses to renin.

PMID- 4354811
TI  - Behaviour of enzymes at high concentration. Use of permeabilised cells in the
      study of enzyme activity and its regulation.

PMID- 4354812
TI  - Stereochemistry of the hydrogen transfer to the coenzyme by octopine
      dehydrogenase.

PMID- 4354814
TI  - Histone phosphorylation in the regenerating rat liver independent of diurnal
      rhythmicity.

PMID- 4354813
TI  - Enzyme kinetic parameters of the fluorescent ATP analogue, 2-aminopurine
      triphosphate.

PMID- 4354815
TI  - Identification of 5-fluorocytidine in RNA from Escherichia coli grown in the
      presence of 5-fluorouracil.

PMID- 4354816
TI  - Phosphorylase phosphatase: molecular configuration and activity.

PMID- 4354817
TI  - Effects of long-acting thyroid stimulator on the reorganization into follicles of
      isolated thyroid cells and on the binding of radioiodinated thyrotropin to
      reassociated cells.

PMID- 4354819
TI  - Glutathione reductase and glutathione peroxidase activities in hepatomous livers
      of rats treated with diethylnitrosamine.

PMID- 4354818
TI  - The superoxide dismutase activity of human erythrocuprein.

PMID- 4354820
TI  - Carbohydrate composition and sequence analysis of cell surface components by mass
      spectrometry. Characterization of the major monosialoganglioside of brain.

PMID- 4354821
TI  - Cytochrome c linked nicotinic acid hydroxylase in Pseudomonas ovalis Chester.

PMID- 4354823
TI  - Preparation of antisera to alpha-fetoprotein making use of estradiol affinity
      column.

PMID- 4354822
TI  - Estrogen receptor: loss of DNA binding ability following trypsin or Ca2+
      treatment.

PMID- 4354824
TI  - [Influence of adrenalectomy on emotional behavior and brain methamphetamine
      concentration in rats--effect of chronic administrations of ACTH].

PMID- 4354825
TI  - Electron microscopic examination of hepatic subcellular fractions for
      phosphatases.

PMID- 4354826
TI  - The production of IgE and IgG1 antibodies in guinea-pigs immunized with antigen
      and bacterial lipopolysaccharides.

PMID- 4354827
TI  - Stimulation of transplantation immunity and plasma cell reaction by interferon in
      mice.

PMID- 4354828
TI  - Guinea-pig reaginic antibody. II. Physicochemical and biological properties.

PMID- 4354829
TI  - The redox behavior of metallo octaethylporphyrins.

PMID- 4354830
TI  - Structure of analogs of nicotinamide-adenine dinucleotide. I. Crystal structure
      of N-(3-(aden-9-yl)propyl)-3-carbamoylpyridinium bromide trihydrate, (Ade-C3
      Nic+)Br-3H2O.

PMID- 4354831
TI  - Structures of analogs of nicotinamide-adenine dinucleotide. II. Crystal structure
      of N-(3-(Aden-9-yl) propyl)-3-carbamoylpyridinium bromide hydrobromide dihydrate,
      (AdeH plus-C3-Nic+)2Br-2H2O.

PMID- 4354832
TI  - Structures of analogs of nicotinamide-adenine dinucleotide. 3. Crystal structure
      of 1,1'-trimethylenebisnicotinamide dichloride monohydrate, (Nic plus-C3-Nic+)2CL
      H2O.

PMID- 4354833
TI  - Chemical evolution of a nitrogenase model. VI. The reduction of CN-, N3-, N2O,
      N2, and other substrates by molybdocysteine catalysts in the presence of
      nucleoside phosphates.

PMID- 4354834
TI  - Transmethylation from toxoflavines to nucleophiles.

PMID- 4354835
TI  - Rotamer stability of histidine and histidine derivatives.

PMID- 4354836
TI  - Spectral characteristics of yeast cytochrome c's at the temperature of liquid
      nitrogen.

PMID- 4354837
TI  - Carboxamidomethylation of yeast inorganic pyrophosphatase.

PMID- 4354838
TI  - Effect of carboxyl group modification on some of the enzymatic properties of L
      glutamate dehydrogenase.

PMID- 4354840
TI  - The analysis of estrogenic steroids in urine by high-speed liquid chromatography.

PMID- 4354839
TI  - High-pressure liquid chromatography of modified purine mononucleotides and
      nucleosides.

PMID- 4354842
TI  - Phospholipids and their metabolism.

PMID- 4354841
TI  - Odontogenic myxoma: ultrastructural and histochemical studies.
AB  - An odontogenic myxoma of a maxilla has been examined. Histochemistry of the
      mucosubstance indicated that hyaluronic acid and chondroitin sulphate were
      present. On ultrastructural examination many of the cells in the myxomatous
      tissue were seen with prominent rough endoplasmic reticulum, suggesting a
      secretory function, and possibly the myxomatous ground substance was produced by
      these cells. Cells containing collagen fibrils were found. Epithelial islands
      with intercellular spaces producing an arrangement similar to the stellate
      reticulum of the enamel organ were found, and possibly had developed from
      odontogenic epithelial rests. These islands were surrounded by a clear zone,
      outside which were cells with an increased prominence of adenosine
      triphosphatase, nucleoside-diphosphatase, thiamine-pyrophosphatase, and often
      arylamidase reaction products. This probably represents a reaction of the
      mesodermal tissue to the epithelial islands. Possibly the epithelium exerts an
      inductive effect on the mesodermal tissue, and the myxomatous appearance may be
      the result of an aberrant development of mesodermal cells into ;myxoblasts' which
      secrete the myxomatous ground substance.

PMID- 4354843
TI  - Lipid methodology.

PMID- 4354845
TI  - Classification of lipoproteins and lipoprotein disorders.

PMID- 4354844
TI  - Cholesterol metabolism.

PMID- 4354846
TI  - Lipoprotein fractionation.

PMID- 4354848
TI  - Benzyl 6-oxopenicillanate and derivatives. II.

PMID- 4354849
TI  - [L-dopa therapy of narcolepsy. Observation of clinical course and polygraphic EEG
      night sleep and day leads].

PMID- 4354847
TI  - Plasma triglyceride metabolism.

PMID- 4354850
TI  - [Endothelial tubular inclusions in insuloma with amyloid stroma].

PMID- 4354851
TI  - Electron carriers of cytochrome oxidase detectable by electron paramagnetic
      resonance and their relationship to those traditionally recognized in this
      enzyme.
AB  - On the basis of oxidoreductive rapid kinetic and titration experiments with
      purified cytochrome c oxidase (EC 1.9.3.1), monitored by electron paramagnetic
      resonance (EPR) at 13 degrees K and by spectrophotometry at 100 degrees K, a new
      assignment of EPR signals is proposed. The bulk of both the low-spin (g = 3.0;
      2.2; 1.5) and highspin (g = 6; 2) signals is attributed to the component with the
      properties of traditional cytochrome a. It is further proposed that the
      absorption band at 655 nm represents the most unambiguous manifestation of the
      a(3) component.

PMID- 4354852
TI  - Malignant lymphoma in cottontop marmosets after inoculation with Epstein-Barr
      virus.
AB  - Neoplasia resembling human malignant lymphoma, reticulum cell sarcoma type,
      occurred in cottontop marmosets inoculated with materials containing Epstein-Barr
      virus. One of four monkeys that received autologous cells transformed in vitro by
      Epstein-Barr virus developed lymphoma in mesenteric lymph nodes 7.5 months after
      inoculation. Three of four marmosets inoculated with cell-free Epstein-Barr virus
      developed lymphoma. The latent period for detectable tumor formation after
      addition of virus was 31-46 days. Immunosuppressive drugs given with the virus
      accelerated the course of disease. Nevertheless, malignant lymphoma occurred in
      an animal given only cell-free virus. Six of eight marmosets inoculated with the
      virus demonstrated antibodies to the virus. Four marmosets not exposed to the
      virus, including two that received immunosuppressive drugs, developed neither
      tumors nor antibodies to Epstein-Barr virus. Virus antigen detectable by
      immunofluorescence was found in 5% of cells shed from one tumor maintained in
      organ culture. These results imply that Epstein-Barr virus is capable of inducing
      malignant lymphoma in at least one primate species. Additional evidence is
      required before its oncogenic capacity in this host can be accepted without
      reservation.

PMID- 4354853
TI  - Independent segregation of the H-2 locus and the locus for responsiveness to
      histamine-sensitizing factor.
AB  - The inheritance of responsiveness to histamine-sensitizing factor of pertussis
      bacilli was examined in (SWR/J x CBA/J)F(1) x CBA/J backcross mice. We found that
      about half of the backcross mice inherited this responsiveness in both sexes.
      There was no linkage between the inheritance of responsiveness to histamine
      sensitizing factor and the H-2(q) locus from the sensitive SW/J progenitor.

PMID- 4354854
TI  - Cyclic adenosine monophosphate receptor: loss of cAMP-dependent DNA binding
      activity after proteolysis in the presence of cyclic adenosine monophosphate.
AB  - The cAMP receptor requires cAMP for DNA binding at pH 8.0 but shows cAMP
      independent DNA binding at pH 6.0. Incubation of the cAMP receptor with
      proteolytic enzymes in the presence of cAMP results in loss of DNA-binding
      ability at pH 8, while it is still able to bind cAMP and DNA at pH 6. Incubation
      with proteolytic enzyme in the absence of cAMP does not affect the DNA-binding
      properties of the cAMP receptor. After proteolysis in the presence of cAMP,
      analysis by sodium dodecyl sulfateacrylamide-gel electrophoresis shows that the
      22,500-dalton subunit characteristic of the untreated protein has been completely
      replaced by a 12,500-dalton fragment.

PMID- 4354856
TI  - Host restriction of Friend leukemia virus. Role of the viral outer coat.
AB  - Host restriction of oncogenesis of RNA tumor viruses in vivo is associated with
      several gene loci. One of these genes, the Fv-1 locus in mice, is expressed in
      vitro and may be studied in mouse-embryo cultures that are restrictive or
      permissive for replication of Friend leukemia virus. Two strains of Friend
      leukemia virus, N-or B-tropic, show reciprocal ability to replicate successfully
      in either NIH Swiss (N-type) or BALB/c (B-type) cells that differ at the Fv-1
      locus. These two strains of virus and two cell lines form a system to measure
      host restriction in vitro. Measurement of adsorption of Friend leukemia virus to
      permissive or restrictive cells reveals no difference in rate or total amount of
      virus bound. Furthermore, studies with virions of vesicular stomatitis virus
      phenotypically mixed within an envelope containing Friend leukemia virus protein
      show no differences in penetration or replication of vesicular stomatitis virus.
      These results strongly suggest that host restriction of Friend leukemia virus is
      due to an intracellular event in the viral replication cycle.

PMID- 4354855
TI  - An immobilized three-enzyme system: a model for microenvironmental
      compartmentation in mitochondria.
AB  - An immobilized three-enzyme system, malate dehydrogenase (EC 1.1.1.37)-citrate
      synthase (EC 4.1.3.7)-lactate dehydrogenase (EC 1.1.1.27), was investigated as a
      model for the rate of oxalacetate production and utilization in mitochondria.
      Lactate dehydrogenase is included to mimic the NADH-utilizing system of
      mitochondria. This three-enzyme system was immobilized in three different ways
      (1) on Sephadex G-50 (surface coupling), (2) on Sepharose 4B (internal-external
      coupling), and (3) entrapped in polycrylamide gel. The rate of citrate production
      from malate, NAD(+), and acetyl CoA was determined continuously in a flow system.
      Up to about 100% rate enhancements were observed when the immobilized system was
      compared to identical systems of free enzyme. An even more pronounced increase of
      rate of up to about 400% compared to the soluble system was measured after
      addition of pyruvate (to reoxidize formed NADH). These results are interpreted in
      relation to microenvironmental changes of oxalacetate production and the possible
      organization of enzymes of the Krebs cycle.

PMID- 4354857
TI  - Reexpression of the rat hypoxanthine phosphoribosyltransferase gene in rat-human
      hybrids.
AB  - Fusion of hypoxanthine phosphoribosyltransferase (HPRT)(-) rat hepatoma cells
      with HPRT(+) human fibroblasts yielded hybrid clones that grew in HAT selective
      medium and contained all the rat chromosomes and one to nine human chromosomes.
      Among the retained chromosomes was the human X chromosome. In all clones
      backselected in medium containing 8-azaguanine, human X chromosome was absent.
      Electrophoretic analysis revealed that, without exception, hybrid clones growing
      in HAT medium had an active HPRT enzyme, either human or rat, or both. When these
      clones were backselected in 8-azaguanine, they did not show HPRT enzyme activity.
      Hybrids that contained the human X chromosome also had human glucose-6-phosphate
      dehydrogenase. The observed reexpression of rat HPRT in hybrid cells derived from
      HPRT(-) rat cells suggests that a genetic factor from the human cell determined
      the expression of the rat structural gene for HPRT.

PMID- 4354858
TI  - Replacement of the sequence G-T-phi-C-G(A)- by G-A-U-C-G- in initiator transfer
      RNA of rabbit-liver cytoplasm.
AB  - Eukaryotic cytoplasmic initiator tRNAs lack the sequence G-T-Psi-C-G(A)-, which
      is in every tRNA of known sequence that is active in protein biosynthesis. In
      initiator tRNA of yeast cytoplasm, which is the only eukaryotic initiator tRNA of
      known sequence, this sequence is replaced by G-A-U-C-G-. We now report the
      sequence of a 30-nucleotide-long, 3'-terminal fragment of cytoplasmic initiator
      tRNA of rabbit liver obtained by specific cleavage of the tRNA at the site
      occupied by the modified nucleoside, 7-methyl guanosine. We show (i) that in
      rabbit-liver initiator tRNA also, the sequence G-T-Psi-C-G(A)- is replaced by G-A
      U-C-G- and (ii) that the sequences of loop IV of both the yeast and rabbit-liver
      cytoplasmic initiator tRNAs are identical, A-U-C-G-m(1)-A-A-A-.

PMID- 4354859
TI  - Enzyme loading of erythrocytes.
AB  - We demonstrated that beta-glucosidase and beta-galactosidase can be trapped
      inside erythrocytes by rapid hemolysis of the cell in the presence of these
      enzymes. Enzyme enters only during hemolysis, and optimum uptake occurs within 60
      sec. There is no loss in cell number after hemolysis-induced enzyme uptake, and
      the ghosts have only a slightly increased mean cell volume. Smaller proteins
      enter more readily than larger proteins, although enzymes with a molecular weight
      of at least 180,000 can be readily entrapped by erythrocytes. This finding may
      provide a useful approach to the problem of enzyme replacement in certain
      diseases, including Gaucher's disease.

PMID- 4354860
TI  - Pituitary extracts and steroid hormones in the control of 3T3 cell growth.
AB  - Results are reported showing that pituitary extracts stimulate growth of 3T3
      cells, an established line of mouse fibroblast. Cells were cultured in medium
      containing an organic buffer (HEPES; N-2-hydroxyethylpiperazine-N'-2
      ethanesulfonic acid), which increases the serum requirement for cell growth. The
      pituitary growth-prompting activity is (a) not dialyzable; (b) thermolabile; (c)
      protease sensitive; and (d) enhanced by hydrocortisone (a steroid hormone).
      Activity was quantitatively assayed by measurement of stimulation of cell
      division or [(3)H]thymidine uptake into DNA. The active species is probably
      different from pituitary protein hormones and it seems to be effective at
      concentrations observed for protein hormones in vivo. 3T3 cells transformed by
      simian virus 40 are not responsive to this activity.

PMID- 4354861
TI  - [Cyclic nucleotide-dependent protein kinases--the enzymological aspects and roles
      in the biological system (author's transl)].

PMID- 4354862
TI  - Toward a comparative biochemistry of the cytochromes.

PMID- 4354863
TI  - [Pharmaco-angiography of the kidney].

PMID- 4354864
TI  - Production of hemorrhagic necrosis in guinea pigs with anti-streptococcal
      antisera.

PMID- 4354865
TI  - Non-specific arthralgia and myalgia with subclinical neuropathy. A histochemical
      and histological study.

PMID- 4354866
TI  - Selective secretion of lysosomal enzymes of the Yoshida hepatoma AH 130 in the
      peritoneal fluid.

PMID- 4354867
TI  - Calcium binding to phospholipids from experimental tumors.

PMID- 4354868
TI  - Pseudomonas cytochrome c peroxidase. IX. Molecular weight of the enzyme in
      dodecyl sulfate-polyacrylamide gel electrophoresis.

PMID- 4354869
TI  - Calcification in adenocarcinoma.

PMID- 4354870
TI  - Ultrastructure of the obligately anaerobic bacteria Clostridium kluyveri and Cl.
      acetobutylicum.

PMID- 4354871
TI  - Acute effects of actinomycin D on the binding of tritiated oestradiol by the
      mouse vagina.

PMID- 4354872
TI  - The membrane ATPase of Escherichia coli. I. Release into solution, allotopic
      properties and reconstitution of membrane-bound ATPase.

PMID- 4354873
TI  - Polycation inhibition of chloroplast photosystem I.

PMID- 4354874
TI  - On the triple localization of creatine kinase in heart and skeletal muscle cells
      of the rat: evidence for the existence of myofibrillar and mitochondrial
      isoenzymes.

PMID- 4354875
TI  - Nitrogenase. IV. Simple method of purification to homogeneity of nitrogenase
      components from Azotobacter vinelandii.

PMID- 4354876
TI  - Acylation of Escherichia coli tRNAtrp with 5-methyltryptophan by E. coli
      tryptophanyl-tRNA ligase.

PMID- 4354877
TI  - Regulation of RNA synthesis in Escherichia coli. I. Characterization of cells
      subjected to simultaneous temperature and osmotic shock.

PMID- 4354879
TI  - Superficial hydradenoma of the cheek.

PMID- 4354880
TI  - Activity of adenosine 3',5'-cyclic monophosphate phosphodiesterase in tissues of
      adult locust Schistocerca gregaria L. (Orthoptera).

PMID- 4354881
TI  - The lipid core model of lipoproteins.

PMID- 4354878
TI  - Evidence for de novo synthesis of collagenase by tadpole skin explant.

PMID- 4354882
TI  - [Early gastric carcinoma. Morphological observations and problems].

PMID- 4354883
TI  - [Peripheral nerve damage in dermatozoa hallucinations].

PMID- 4354884
TI  - Effect of aldosterone on cyclic-AMP metabolism in the urinary bladder of the
      toad.

PMID- 4354885
TI  - Cyclic-AMP in the aqueous humor: the effects of repeated topical epinephrine
      administration and sympathetic denervation.

PMID- 4354886
TI  - Cyclic nucleotides and photoreception.

PMID- 4354887
TI  - [Pyoderma gangrenosum, trichopytosis superficialis, eczema herpeticatum, lupus
      vulgaris, acne urticaria, hypertrichosis faciei due to glucocorticoids, malignant
      reticulosis, dyskeratosis follicularis].

PMID- 4354888
TI  - [Letter: Herpes progenitalis caused by Herpes simplex virus type I?].

PMID- 4354889
TI  - Cytotoxic compounds. XVI. Reactions of the bismethanesulphonates of 3-(N
      methylanilino)propane-1,2-diol and of 2-(N-methylanilino)-propane-1,3-diol with
      nucleophiles.

PMID- 4354890
TI  - Isoindole.

PMID- 4354891
TI  - Sizes of end plate compartments, densities of acetylcholine receptor and other
      quantitative aspects of neuromuscular transmission.

PMID- 4354892
TI  - Cellular events in tolerance. I. Failure to demonstrate activation of
      lymphocytes, blocking factors, or suppressor cells during the induction of
      tolerance to a soluble protein.

PMID- 4354893
TI  - Histological and ultrastructural changes in the blastocyst and reproductive tract
      of the roe deer, Capreolus capreolus, during delayed implantation.

PMID- 4354895
TI  - [Serum renin activity and serum angiotensin II--interpretation of the test
      results].

PMID- 4354894
TI  - A re-examination of the role of phospholipids as energy substrates during
      incubation of ram spermatozoa.

PMID- 4354896
TI  - [ACTH--interpretation of test results].

PMID- 4354897
TI  - [Biosynthesis of proinsulin and insulin].

PMID- 4354898
TI  - [Conduction of insulin action: the receptor and transmitter].

PMID- 4354899
TI  - [A focus of familial amyloid polyneuropathy].

PMID- 4354900
TI  - Hormone receptors.

PMID- 4354902
TI  - [Lipiodol ultra fluid hepatography].

PMID- 4354901
TI  - A mutant of Escherichia coli K12 deficient in the 5'-3' exonucleolytic activity
      of DNA polymerase I. I. General characterization.

PMID- 4354903
TI  - Pollicization for congenital deformities of the hand.

PMID- 4354905
TI  - [Cellular immunity in viral infections (author's transl)].

PMID- 4354904
TI  - Associated carcinomata of colon and anus.

PMID- 4354906
TI  - [Protein kinase and cyclic AMP (author's transl)].

PMID- 4354907
TI  - [Artificial assembly of envelope particles of HVJ (Sendai virus) (author's
      transl)].

PMID- 4354909
TI  - [Cell fusion (author's transl)].

PMID- 4354908
TI  - [Interaction of hormone with its receptors (author's transl)].

PMID- 4354910
TI  - [Adenyl cyclase and cyclic AMP in the regulation of myocardial contractility.
      Biochemical and physiological correlations].

PMID- 4354911
TI  - Radiographic appearance of bronchial carcinoid.

PMID- 4354912
TI  - [Viability of the foot-and-mouth disease virus in the body of wild birds].

PMID- 4354913
TI  - [Effect of multiple infection on the reproduction of the virus of foot-and-mouth
      disease].

PMID- 4354914
TI  - [Effect of antibiotics on the properties of the causative agents of anaerobic
      infections].

PMID- 4354915
TI  - [Diagnosis of fowl pox using a hemagglutination inhibition reaction].

PMID- 4354916
TI  - Calcitonin- and ACTH-producing cells in a case of medullary carcinoma of the
      thyroid. Immunofluorescence investigations.

PMID- 4354918
TI  - Liver necrosis, adenovirus type 2 and thymic dysplasia.

PMID- 4354917
TI  - [Occurrence and localization of the carcino-embryonic antigen (CEA) and of a
      perchloric acid-soluble antigen of normal colonic mucosa (NC) in carcinomas and
      polyps of the large bowel (author's transl)].

PMID- 4354919
TI  - [Histochemical findings in trophoblast tumors].

PMID- 4354920
TI  - RNAs as amplifiers of specific signals in immunity.

PMID- 4354921
TI  - Various enzymes involved with putative neurotransmitters. Regional distribution
      in the brain of deceased mentally normal, chronic schizophrenics or organic brain
      syndrome patients.

PMID- 4354922
TI  - [Cross reaction between human breast cancer, mastopathy and murine mamma
      carcinoma: localization of the antigen in type-A-particle-virus].

PMID- 4354923
TI  - Electron microscopy of selectively stimulated microconidiogenesis in wild type
      Neurospora crassa.

PMID- 4354924
TI  - Structure and plugging of septa of wild type and spreading colonial mutants of
      Neurospora crassa.

PMID- 4354925
TI  - The regulation of liver glycogen synthetase D phosphatase by ATP and glucose.

PMID- 4354926
TI  - Modification of polynucleotides by a fragment produced by enzymatic cleavage of S
      (1, 2-dichlorovinyl)-L-cysteine.

PMID- 4354927
TI  - A preliminary immunochemical study of E. coli aspartokinase I-homoserine
      dehydrogenase I.

PMID- 4354928
TI  - Binding of progesterone by rat uterus in vitro.

PMID- 4354929
TI  - Subunits of oncornavirus high-molecular-weight RNA. I. Stepwise conversion of 60
      S AMV (avian myeloblastosis virus) RNA to subunits.

PMID- 4354930
TI  - Low temperature electron paramagnetic resonance studies on two iron-sulfur
      centers in cardiac succinate dehydrogenase.

PMID- 4354931
TI  - 13C nuclear magnetic resonance studies of the conformation of the X-pro bond in
      the oligopeptide hormones, thyrotropin-releasing hormone, luteinizing hormone
      releasing factor, angiotensin and melanocyte-stimulating hormone release
      inhibiting factor.

PMID- 4354932
TI  - Alanine formation by rat muscle homogenate.

PMID- 4354934
TI  - Adenosine 3', 5'-monophosphate-dependent protein kinase in adipose tissue:
      inhibition by tolbutamide.

PMID- 4354933
TI  - Alternate pathways of D-fructose transport and metabolism in Arthrobacter
      pyridinolis.

PMID- 4354935
TI  - Conversion of DNA polymerase extracted from rat ascites hepatoma cells.

PMID- 4354936
TI  - Effect of cytochalasin B on lymphocyte stimulation induced by concanavalin A or
      periodate.

PMID- 4354937
TI  - Adenosine 3',5' monophosphate binds only to the inner surface of human
      erythrocyte membranes.

PMID- 4354938
TI  - A spin-label for RNA study.

PMID- 4354939
TI  - Binding of thyrotropin releasing hormone by thyrotropin-secreting cells.

PMID- 4354940
TI  - The molecular weight of NADPH-cytochrome C reductase isolated by
      immunoprecipitation from detergent-solubilized rat liver microsomes.

PMID- 4354941
TI  - Gluconate metabolism in Pseudomonas: a novel pathway of glyceraldehyde-3
      phosphate metabolism.

PMID- 4354942
TI  - Cyclic nucleotide-dependent protein kinases of the rat pancreas.

PMID- 4354943
TI  - Control of calcium absorption and intestinal calcium-binding protein synthesis.

PMID- 4354944
TI  - Studies on ATP-dependent deoxyribonuclease of Haemophilus influenzae: involvement
      of the enzyme in the transformation process.

PMID- 4354946
TI  - Protein kinase activity in Morris hepatomas.

PMID- 4354945
TI  - Synthesis in vitro of vesicular stomatitis virus proteins in cytoplasmic extracts
      of L cells.

PMID- 4354947
TI  - Role of 3',5'-cyclic AMP in the control of nuclear protein kinase activity.

PMID- 4354949
TI  - The stability of collagen cross-links when derived from hydroxylsyl residues.

PMID- 4354948
TI  - Endonuclease of high specific activity in a purified mouse interferon
      preparation.

PMID- 4354950
TI  - Effect of catecholamines and ovarian hormones on cyclic AMP accumulation in rat
      hypothalamus.

PMID- 4354951
TI  - Formation of retinol (alpha, beta-32P) pyrophosphate with (gamma-32P) ATP
      catalysed by whole homogenates of rat thyroid.

PMID- 4354952
TI  - An iron tetrahydroporphyrin prosthetic group common to both assimilatory and
      dissimilatory sulfite reductases.

PMID- 4354953
TI  - Similar and opposite effects of dibutyryl cyclic AMP and insulin on glucose
      metabolism in adipose tissue.

PMID- 4354954
TI  - Effects of thyrotropin, prostaglandin E1 and iodide on cyclic 3',5'-AMP
      concentration in dog thyroid slices.

PMID- 4354955
TI  - Development of cyclic AMP metabolism in rat liver. A correlative study of tissue
      levels of cyclic AMP, accumulation of cyclic AMP in slices, adenylate cyclase
      activity and cyclic nucleotide phosphodiesterase activity.

PMID- 4354956
TI  - The role of calcium in the steroidogenic response of rat adrenal cells to
      adrenocorticotropic hormone.

PMID- 4354957
TI  - Gonadotropin receptors in the plasma membranes of rat luteal cells.

PMID- 4354958
TI  - [Analysis of the carbohydrate portion of a glycoprotein from sheep gastric mucosa
      by sequential periodate oxidation].

PMID- 4354959
TI  - [Glycoproteins. XLIX. Isolation and structure of oligosaccharides from the
      neutral fraction of acetolysis of glycoproteins from ovomucoid].

PMID- 4354960
TI  - [Chemical analysis of polysaccharides from wild and phage phi 1(40) converted
      Salmonella johannesburg 5.58].

PMID- 4354961
TI  - Enzyme cytochemical observations on the tissue stages of the life cycle of
      Eimeria acervulina and Eimeria necatrix.

PMID- 4354962
TI  - Changes in oxidative metabolism and ultrastructure accompanying differentiation
      of the mitochondrion in Trypanosoma brucei.

PMID- 4354963
TI  - Paracrystalline arrays in mitochondria following ageing of mitochondria in situ.

PMID- 4354964
TI  - Oat cell carcinoma of the trachea.

PMID- 4354965
TI  - [A study on the role of brain for the establishment of adaptation to the repeated
      immobilization stress. II. A role of the limbic-midbrain system in the repeated
      immobilization stress].

PMID- 4354966
TI  - Effect of the local administration of proteolytic enzymes on the rupture of the
      ovarian follicle in the domestic fowl, Gallus domesticus.

PMID- 4354967
TI  - Metabolism of fatty acids by ovine spermatozoa.

PMID- 4354968
TI  - Phospholipid composition of bovine sperm fractions, seminal plasma and
      cytoplasmic droplets.

PMID- 4354969
TI  - Effect of morphine administration on adenyl cyclase and 3',5'-cyclic nucleotide
      phosphodiesterase activities in the brain.

PMID- 4354970
TI  - Modification of Baird-Parker's classification system of Staphylococcus albus.

PMID- 4354972
TI  - The detection of different progenies induced by fractionated infectious
      poliovirus RNA.

PMID- 4354971
TI  - Latent infection of monkeys with oncogenic herpes viruses.

PMID- 4354974
TI  - The role of lysosomes in virus-induced cell fusion. 2. Modification of the cell
      surface.

PMID- 4354973
TI  - Simple preparation of 3H-labelled poliovirus for chromatographic strain
      differentiation with aluminium hydroxide and one-year control of labelled
      reference strains.

PMID- 4354975
TI  - The role of lysosomes in virus-induced cell fusion. 1. Cytochemical studies.

PMID- 4354977
TI  - [Symptoms and treatment of para-neoplastic endocrine diseases].

PMID- 4354976
TI  - A study of the conformational properties of hemoglobin by the method of two
      paramagnetic labels.

PMID- 4354978
TI  - [Paraneoplastic endocrine syndrome with a retroperitoneal paraganglioma].

PMID- 4354979
TI  - [Post-synaptic potentials of facial nerve nucleus motor neurons evoked by
      afferent and corticofugal impulsation].

PMID- 4354980
TI  - [The relationship between the character of synaptic influences and the direction
      of shifts in the concentration of RNA in rat spinal cord motor neurons].

PMID- 4354981
TI  - [The evolution of neuronal systems for suprasegmentary motor control (review)].

PMID- 4354982
TI  - [Cortico-and rubrofugal activation of interneurons forming the propriospinal
      tracts of the dorsolateral funiculus of the cat spinal cord].

PMID- 4354983
TI  - [The origin of the period of post-activation depression in somato-and viscero
      sympathetic reactions].

PMID- 4354985
TI  - [Participation of hippocampal neurons in the generation of theta waves].

PMID- 4354984
TI  - [The functional organization of mechanisms of presynaptic inhibition evoked by
      stimulation of cutaneous afferents].

PMID- 4354986
TI  - ["Habituation" of post-synaptic neuronal reactions of the cat motor cortex to
      multi-modal stimulation].

PMID- 4354987
TI  - [The synaptic nature of the basic components of the evoked potential of the
      general cortex of the turtle forebrain].

PMID- 4354989
TI  - [Synaptic mechanisms of regulating the impulse activity of a receptor neuron in
      the stretch receptor--abdominal nerve chain system of crustacea].

PMID- 4354988
TI  - [A study of the distribution of synaptic inputs on an analogous model of motor
      neurons].

PMID- 4354990
TI  - Some properties of cortisol-receptor complex isolated from cytoplasm of rat liver
      and its effect on biosynthesis of nuclear RNA.

PMID- 4354991
TI  - In vitro effects of ACTH on uridine incorporation into rapidly labelled adrenal
      RNA of normal and dexamethasone-suppressed rats.

PMID- 4354993
TI  - Estrogen receptor protein of pancreas.

PMID- 4354992
TI  - Demonstration of a specific binding protein for testosterone and 5alpha
      dihydrotestosterone in rabbit serum. Separation from the corticosteroid binding
      globulin (CBG).

PMID- 4354994
TI  - [Glomus tumour (so-called chemodectoma) of the lung. Pathological and biochemical
      findings].

PMID- 4354995
TI  - [Ultrastructural study of human clostridial gas gangrene].

PMID- 4354996
TI  - [In vitro effect of hyperthermia on the incorporation rate of nucleic acid
      precursors in tumours and normal tissues].

PMID- 4354997
TI  - [Effect of hyperthermia on the growth of a heterotransplanted human sigma
      carcinoma (tumor GW-39)].

PMID- 4354998
TI  - Water soluble proteins from rat brain and from experimental tumors of rat nervous
      system.

PMID- 4354999
TI  - [Deoxyribonucleases and phosphatases of rat liver carcinomas induced by
      diethylnitrosamine].

PMID- 4355000
TI  - 1-Nitroso-5, 6-dihydrouracil: induction of liver cell carcinomas and kidney
      adenomas in the rat.

PMID- 4355001
TI  - [Electronmicroscopic observations on mouse mammary tumor virus (MTV) with special
      regard to the extrusion of A-particles].

PMID- 4355003
TI  - [Biopsy of the connective branch of the gastrocnemius and posterior cutaneous
      intermediate nerve of the foot as a method of diagnosing various disorders of the
      primary sensory neuron].

PMID- 4355004
TI  - [The basis for various methods of rehabilitative therapy in the early and initial
      residual stages of juvenile cerebral palsy].

PMID- 4355002
TI  - [Lactate dehydrogenase activity and isoenzyme patterns in the diagnosis of benign
      and malignant brain tumors].

PMID- 4355005
TI  - Epidemiology of respiratory syncytial virus infection in Washington, D.C. I.
      Importance of the virus in different respiratory tract disease syndromes and
      temporal distribution of infection.

PMID- 4355006
TI  - Adrenocortical function after major gastric surgery.

PMID- 4355008
TI  - Granular cell myoblastoma of the breast.

PMID- 4355007
TI  - Alteration in liver mitochondrial metabolism in a patient with biliary
      obstruction due to liver carcinoma.

PMID- 4355010
TI  - Bovine respiratory secretion as a two-phase system. Effect of parainfluenza-3
      virus on the rheologic properties of the phases.

PMID- 4355009
TI  - Pentamidine isothionate levels in lungs, livers, and kidneys of rats after
      aerosol or intramuscular administration.

PMID- 4355011
TI  - Persistent infection with parainfluenza type 3 virus in man.

PMID- 4355012
TI  - Pulmonary blastoma.

PMID- 4355013
TI  - Changes in the lipid and fatty acid composition of developing rabbit brain.

PMID- 4355014
TI  - The mechanism of inhibition by fluoride of fatty acid oxidation in uncoupled
      mitochondria.

PMID- 4355015
TI  - Further characterization of fatty acyl monoester lipase from human adipose
      tissue.

PMID- 4355016
TI  - Free and sulphate-conjugated 16-unsaturated C19 steroids in human testis tissue.

PMID- 4355018
TI  - The acyl lipids of highly purified plant mitochondria.

PMID- 4355017
TI  - Tetrahydropteridine-dependent cleavage enzyme for O-alkyl lipids: substrate
      specificity.

PMID- 4355019
TI  - 5'-Nucleotide phosphodiesterase isoenzyme pattern in the serum of human hepatoma.

PMID- 4355020
TI  - Comparison of cell coat acid mucopolysaccharides of normal liver and various
      ascites hepatoma cells.

PMID- 4355021
TI  - Guanosine anabolism for biosynthesis of nucleic acids in Novikoff ascites rat
      tumor cells in culture.

PMID- 4355022
TI  - The effect of pH on the morphology, electrophoretic mobility, and infectivity of
      the mouse mammary tumor virus.

PMID- 4355023
TI  - Virus morphogenesis in a mouse lymphoma.

PMID- 4355024
TI  - Effects of the antineoplastic alkaloid acronycine on the ultrastructure and
      growth patterns of cultured cells.

PMID- 4355025
TI  - Incorporation of 2-deoxy-D-glucose into glucoproteins of normal and Simian virus
      40-transformed hamster cells.

PMID- 4355026
TI  - Tissue culture and animal studies with an oncolytic bovine enterovirus (bovine
      enterovirus 1).

PMID- 4355027
TI  - Purine nucleotide metabolism and nucleotide pool sizes in synchronized lymphoma
      L5178Y cells.

PMID- 4355028
TI  - The protective effect of estradiol-17 beta against polycyclic hydrocarbon
      cytotoxicity.

PMID- 4355029
TI  - Genetic factors in chronic remittent Friend disease.

PMID- 4355030
TI  - Competitive DNA-RNA hybridization of nuclear and microsomal RNA in normal,
      neoplastic, and neonatal liver tissue.

PMID- 4355031
TI  - Electron microscopic study of lymphatic tissues of mice inoculated with a
      leukemogenic extract from radiation-induced tumors.

PMID- 4355032
TI  - Collagenolytic activity in malignant melanoma: physiocochemical studies.

PMID- 4355033
TI  - Transfer RNA methylases and transfer RNA-methylated bases of polyoma virus
      transformed and spontaneously transformed mouse culture cells.

PMID- 4355034
TI  - Expression of tumor-specific antigens in mouse somatic cell hybrids.

PMID- 4355035
TI  - Further observations on the activation and inhibition of lipoprotein lipase by
      apolipoproteins.

PMID- 4355036
TI  - Mechanisms of activation of cardiac glycogen phosphorylase in ischemia and
      anoxia.

PMID- 4355037
TI  - Contribution of intrarenal generation of prostaglandin to autoregulation of renal
      blood flow in the dog.

PMID- 4355038
TI  - Differential response of large and small coronary arteries to nitroglycerin and
      angiotensin. Autoregulation and tachyphylaxis.

PMID- 4355039
TI  - Improved techniques for assessment of serum lipoprotein patterns. II. Rapid
      method for diagnosis of type 3 hyperlipoproteinemia without ultracentrifugation.

PMID- 4355040
TI  - Rapid determination of ammonia in a perchloric acid supernate from blood, by use
      of an ammonia-specific electrode.

PMID- 4355041
TI  - Improved method for determination of triglycerides in serum.

PMID- 4355042
TI  - Measurement of carcinoembryonic antigen.

PMID- 4355043
TI  - Contact sensitivity in vitro. The production of macrophage inhibition factors
      from DNCB sensitized lymphocytes by subcellular organelles obtained from DNCB
      epidermal tissue.

PMID- 4355044
TI  - Simian virus 40-induced retinopathy in the rat.

PMID- 4355045
TI  - Increased sensitivity to theophylline associated with primary open-angle
      glaucoma.

PMID- 4355046
TI  - Bluetongue virus in exotic ruminants.

PMID- 4355047
TI  - An epornitic of duck virus enteritis (duck plague) in California.

PMID- 4355048
TI  - Cheddar cheese as a vehicle for viruses.

PMID- 4355049
TI  - Characterization of brain cerebrosides at early stages of development in the rat.

PMID- 4355050
TI  - Stimulatory effect of L-vasopressin on PMSG-induced ovulation in immature rats.

PMID- 4355051
TI  - Activity of mitochondrial enzymes in mouse embryos.

PMID- 4355052
TI  - Congenital mesoblastic nephroma (leiomyomatous hamartoma): first adult case.

PMID- 4355053
TI  - Granular cell myoblastoma of the bladder: report of an additional case.

PMID- 4355054
TI  - Massive adrenal hemorrhage in the newborn: 2 surviving cases by surgical
      treatment.

PMID- 4355055
TI  - Benign renal tumors in children: report of a case.

PMID- 4355056
TI  - Retroperitoneal lipoblastic tumors in children.

PMID- 4355058
TI  - Pseudohypoparathyroidism type II: a possible defect in the reception of the
      cyclic AMP signal.

PMID- 4355057
TI  - Some observations on the pathogenesis of Bartter's syndrome.

PMID- 4355059
TI  - Letter: Role of microtubules in lipoprotein secretion by the liver.

PMID- 4355060
TI  - Prebiotic activation processes.

PMID- 4355061
TI  - Peptide formation mediated by cyanate.

PMID- 4355062
TI  - Letter: Ribonucleoprotein particle in epidermis cells as the receptor for
      juvenile hormone.

PMID- 4355063
TI  - Guanidine hydrochloride in the Eaton-Lambert syndrome. Electrophysiologic
      improvement.

PMID- 4355064
TI  - Bacterial meningitis. A symposium. 3. Morbid anatomical changes.

PMID- 4355065
TI  - Diagnostic open lung biopsy in the critically ill child.

PMID- 4355067
TI  - Distension dacryocystography.

PMID- 4355066
TI  - Debridement of experimental skin burns of pigs with bromelain, a pineapple-stem
      enzyme.

PMID- 4355068
TI  - Idiopathic intestinal lymphangiectasis (primary protein-losing enteropathy).
      Lymphographic verification of enteric and peritoneal leakage of chyle.

PMID- 4355069
TI  - 99mTc-diphosphonate concentration in primary breast carcinoma.

PMID- 4355071
TI  - Ultrasonic holography. A promising medical imaging tool.

PMID- 4355070
TI  - Suppression of 99mTc-pertechnetate uptake in a choroid plexus papilloma.

PMID- 4355072
TI  - Evaluation of 99mTc-pyrophosphate as a bone imaging agent.

PMID- 4355073
TI  - Comparison of growth acceleration of pituitary dwarfs treated with anabolic
      steroid and thyroid hormone with normal growth spurt.

PMID- 4355074
TI  - Paradoxical response of plasma cortisol to pulse intravenous injection of
      synthetic corticotrophin and dibutyryl cyclic adenosine 3',5'-monophosphate in
      adult panhypopituitarism.

PMID- 4355076
TI  - The simultaneous assay of cortisol and 17alpha-hydroxyprogesterone in the plasma
      of patients with congenital adrenal hyperplasia.

PMID- 4355075
TI  - "In vivo radioimmunoassay" of aldosterone.

PMID- 4355077
TI  - The clinical pattern and prognosis of patients with amebic liver abscess and
      jaundice.

PMID- 4355078
TI  - Studies on human conception.

PMID- 4355079
TI  - Social service casefinding in the hospital--its influence on the utilization of
      social services.

PMID- 4355080
TI  - [Metabolism of ribonucleic acid and proteins in spermatocytes and spermatids of
      the ram (Ovis aries). II. Cytochemical study of protein transformations in old
      spermatids].

PMID- 4355081
TI  - Streptozotocin for malignant insulinomas and carcinoid tumor. Report of eight
      cases and review of the literature.

PMID- 4355082
TI  - Pituitary gigantism. A case report and review.

PMID- 4355083
TI  - Aberrant behavior of phosphofructokinase from otosclerotic stapedes. Biochemical
      evidence and the metabolic consequences.

PMID- 4355084
TI  - Editorial: Extra-articular lesions of rheumatoid arthritis.

PMID- 4355085
TI  - Clinical experience with two new methanesulfonic acid esters of aminoglycols, NSC
      140115 and NSC-140117, in the treatment of malignant lymphoma.

PMID- 4355086
TI  - [Clinical picture and treatment of insulin resistance in primary
      hyperlipoproteinaemia (author's transl)].

PMID- 4355087
TI  - [Ineffectiveness of cytochrome c on experimental death angel poisoning].

PMID- 4355089
TI  - [Annulate lamellae in the cellular structure of glioblastoma Bowmani of the brain
      in man].

PMID- 4355088
TI  - [Early effect of cortisol on glucose phosphatase activity in the rat liver].

PMID- 4355090
TI  - [Qualitative changes in prostaglandins in kidneys of normotonic and hypertonic
      animals under the effect of aspirin-like preparations].

PMID- 4355091
TI  - Estimation of ACTH reserve on normal and hypopituitary subjects: comparison of
      oral and intravenous metyrapone with insulin hypoglycemia.

PMID- 4355092
TI  - Circadian rhythm in the urinary excretion of cyclic 3',5'-adenosine monophosphate
      in man.

PMID- 4355094
TI  - Release of transmitter from degenerating locust motorneurones.

PMID- 4355093
TI  - Isolation of angiotensin II binding proteins from normal human plasma by affinity
      chromatography.

PMID- 4355095
TI  - Cell-associated nonesterified fatty acid levels and their alteration during
      lipolysis in the isolated mouse adipose cell.
AB  - A rapid and flexible method has been developed for measuring cell-associated,
      probably intracellular, nonesterified fatty acids (CAFA) in isolated mouse
      adipose cells. A variety of lipolytic agents as well as various concentrations of
      epinephrine elevate CAFA levels in rough proportion to their stimulation of
      glycerol and fatty acid release. Insulin reduces epinephrine-elevated CAFA
      levels. A detailed, quantitative study of the relationship among lipolytic
      activity, CAFA levels, and the extracellular molar ratio of fatty acids to
      albumin has been carried out. Epinephrine-elevated CAFA levels rise linearly
      with, while epinephrine-stimulated lipolytic activity is independent of, fatty
      acid to albumin ratios below 2-3. As the ratio increases from 3 to 5, CAFA levels
      continue to increase, whereas lipolytic activity decreases. Above ratios of 5,
      fatty acid release almost completely ceases; CAFA levels increase dramatically
      with residual glycerol release. A temperature-dependent efflux of epinephrine
      elevated CAFA can be elicited through blockade of stimulated lipolysis with
      propranolol, but only in the presence of extracellular fatty acid to albumin
      ratios below 3. These observations suggest that during stimulated lipolysis, a
      fatty acid gradient exists between the cell and extracellular serum albumin and
      that CAFA represent the intracellular component of this gradient. In addition,
      these observations support the concept that intracellular fatty acids play a role
      in the feedback regulation of adipose cell function as extracellular fatty acids
      accumulate during the lipolytic response.

PMID- 4355096
TI  - Bimodal effect of insulin on hormone-stimulated lipolysis: relation to
      intracellular 3',5'-cyclic adenylic acid and free fatty acid levels.
AB  - The present study was undertaken to determine the relationship between the
      antilipolytic and lipolytic effects of insulin on hormone-stimulated lipolysis
      and the mechanisms of these reactions. The dose-response curve of norepinephrine
      stimulated lipolysis in rat adipocytes was not sigmoidal but biphasic in nature.
      Intracellular free fatty acid levels were linearly related to lipolytic rate and
      also described a biphasic profile in response to increments in norepinephrine
      concentration. Intracellular 3',5'-cyclic AMP levels measured 10 min after
      addition of increasing concentrations of norepinephrine showed a rise and a
      plateau followed by a secondary rise. Insulin was antilipolytic at low
      concentrations of norepinephrine and distinctly lipolytic at high concentrations.
      The combined antilipolytic and lipolytic effect of insulin is termed the
      "bimodal" effect of insulin on hormone-stimulated lipolysis. The bimodal effect
      of insulin correlated positively with changes in peak intracellular 3',5'-cyclic
      AMP levels. In the presence of glucose, insulin invariably enhanced lipolysis. It
      is suggested that the antilipolytic effect of insulin is achieved by both
      inhibition of adenyl cyclase activity and activation of low-K(m) 3',5'-cyclic AMP
      phosphodiesterase, the net effect being a low accumulation of 3',5'-cyclic AMP.
      On the other hand, the lipolytic effect of insulin probably reflects enhancement
      of adenyl cyclase activity to an extent that overrides any activation of low-K(m)
      3',5'-cyclic AMP phosphodiesterase activity, resulting in an increase in peak
      adipocyte 3',5'-cyclic AMP levels.

PMID- 4355099
TI  - [Holders for silica-gel pearls for removal of cataract (silico-extractors)].

PMID- 4355097
TI  - Fatty acid oxidation and esterification in isolated rat hepatocytes: regulation
      by dibutyryl adenosine 3',5'-cyclic monophosphate.
AB  - Isolated rat hepatocytes rapidly utilized [(14)C]palmitate and, in particular,
      synthesized large amounts of neutral lipids from palmitate. Incorporation into
      cellular lipids occurred at a linear rate proportional to the medium
      concentration of fatty acids. Oxidation of [(14)C]palmitate to CO(2) increased
      with time and was much slower than palmitate esterification. Since [(14)C]acetate
      and [(14)C]glucose were oxidized to CO(2) at a linear rate, the lag in fatty acid
      oxidation to CO(2) did not involve enzymatic steps subsequent to acetate
      formation. The relative contribution of palmitate to esterification and to CO(2)
      formation depended upon the molar ratio of palmitate to albumin (v) and the
      length of incubation. Dibutyryl cyclic AMP (1 mM) reduced the oxidation of
      palmitate and acetate to CO(2) by about 50 and 90%, respectively, but did not
      alter palmitate esterification. However, equivalent concentrations of sodium
      butyrate produced similar decreases in CO(2) formation. Dibutyryl cyclic AMP (1
      mM) also stimulated palmitate oxidation to water-soluble products, principally
      ketone bodies, by 50-100%. Sodium butyrate exerted no effect, while monobutyryl
      cyclic AMP and cyclic AMP both stimulated this pathway significantly. These
      results indicate that both v and dibutyryl cyclic AMP regulate the metabolism of
      fatty acids by isolated hepatocytes and suggest that hormonal stimulation of
      adenyl cyclase controls hepatic lipid metabolism.

PMID- 4355098
TI  - Letter: The role of antimicrobial agents in the treatment of pertussis.

PMID- 4355100
TI  - Cell surface changes in virus-induced cell fusion. 2. Changes in cell coat
      thickness.

PMID- 4355101
TI  - [Therapy of polyneuritis].

PMID- 4355102
TI  - Cyclic AMP and cyclic GMP enhance growth of chick embryo fibroblasts.

PMID- 4355103
TI  - Selective agglutination of pathogenic strains of Entamoeba histolytica induced
      con A.

PMID- 4355104
TI  - Cushing's syndrome and pregnancy.

PMID- 4355105
TI  - Metastatic cancer of the pituitary gland.

PMID- 4355106
TI  - Effects of ethanol on amino-acid uptake and utilization by the liver and other
      organs of rats.

PMID- 4355108
TI  - Adenosine 3',5'-monophosphate metabolism in the liver in experimental hemorrhagic
      shock.

PMID- 4355107
TI  - [Epidemics of leptospirosis and ornithosis in unusual epidemiological
      conditions].

PMID- 4355109
TI  - Spontaneous rupture of the liver caused by hepatomas.

PMID- 4355111
TI  - 5-Bromodeoxyuridine incorporation into simian virus 40 deoxyribonucleic acid.
      Effects on simian virus 40 replication in monkey cells.

PMID- 4355110
TI  - Clinical liver heterotopic (auxiliary) transplantation.

PMID- 4355112
TI  - Transformation of mammalian cells by DNA-containing viruses following
      photodynamic inactivation.

PMID- 4355113
TI  - Crystallization of human rhinovirus 1A.

PMID- 4355114
TI  - Formation of syncytia in human lymphoblastoid cells infected with type C viruses.

PMID- 4355115
TI  - Establishment of repression by bacteriophage lambda: lack of a direct regulatory
      effect of cyclic AMP.

PMID- 4355116
TI  - The effect of cordycepin on cell transformation by RNA tumor viruses.

PMID- 4355117
TI  - Presence of a thermosensitive step in the course of transformation by SE-polyoma
      virus.

PMID- 4355118
TI  - Effects of pH on the structure of vesicular stomatitis virus.

PMID- 4355119
TI  - Polypeptide composition of measles and canine distemper viruses.

PMID- 4355121
TI  - [The fine structure of the cyst stages of Sarcocystis tenella (authors transl)].

PMID- 4355122
TI  - A national view of mental health.

PMID- 4355120
TI  - [Light- and electronmicroscopic studies on mastigote and amastigote stages of
      Trypanosoma cruzi under the influence of Lampit (author's transl)].

PMID- 4355123
TI  - Phosphodiesterase inhibition and vascular activity of papaverine metabolites.

PMID- 4355125
TI  - Renal histology and clinical course of systemic lupus erythematosus. A
      prospective study.

PMID- 4355126
TI  - Letter: Comparing serologic data.

PMID- 4355124
TI  - Analysis of the peristaltic reflex in vitro: effects of some antagonists.

PMID- 4355129
TI  - [Paraneoplastic endocrine syndrome after a voluminous malignant retroperitoneal
      nonchromaffin paraganglioma].

PMID- 4355128
TI  - The presence of a hormone-sensitive cyclase system in the rat aorta and its
      relation to lipolysis.

PMID- 4355130
TI  - Attempts to find a specific intranuclear location for replication polyoma virus
      DNA.

PMID- 4355127
TI  - Acid mucosubstances underlying lipid deposits in ageing tendons and
      atherosclerotic arteries.

PMID- 4355132
TI  - Toxicity, analysis, and production of aspergillic acid and its analogues.

PMID- 4355131
TI  - Intracellular distribution of steroid glycosidases of rabbit liver.

PMID- 4355133
TI  - A comparative study of the corneal graft reaction in allo- and xenogeneic models.

PMID- 4355135
TI  - Renin in hypertension: how important as a risk factor?
AB  - An analysis of the plasma renin levels in relation to the incidence of severe
      cardiovascular complications (coronary thrombosis, stroke, ruptured aortic
      aneurysm) was made in 325 patients with various types of hypertension. These
      patients had one to four measurements of plasma renin activity taken under
      standard conditions of sodium intake and posture in the period 1963-68. The
      follow-up was 5 to 10 years in the four groups of hypertensive patients
      (essential hypertension, malignant hypertension, hypertension secondary to renal
      parenchymatous disease and hypertension caused by, or associated with, renal
      artery obstruction). For all 325 patients, the incidence of such complications
      was 23.6, 20.4 and 44.7% in the low, normal and high renin groups. These findings
      are at variance with the claim that renin constitutes a serious risk factor in
      hypertensive patients, especially if it is isolated from other parameters such as
      the level of diastolic pressure, the adequacy of kidney function, the
      effectiveness of dietary and drug management of hypertension, and especially the
      presence or absence of atherosclerotic lesions of the large vessels at the time
      of the renin determination.

PMID- 4355134
TI  - Editorial: New knowledge of benign essential hypertension.

PMID- 4355136
TI  - Role of cell-mediated immunity in the recovery of cattle from primary and
      recurrent infections with infectious bovine rhinotracheitis virus.
AB  - When cattle infected with infectious bovine rhinotracheitis virus (IBRV) were
      treated 3 months later with a synthetic corticosteroid, consistent recrudescence
      of the infection was observed. Suppression of cell-mediated immunity, as measured
      by lymphocyte transformation responses, could be demonstrated at the time of
      recrudescence. Treatment with adrenocorticotropic hormone and trigeminal
      neurotomy also resulted in recrudescence of IBRV, but immunosuppression was not
      detected in these animals. The detection of specific, antigen-induced, lymphocyte
      transformation responses at the time of recovery from both primary and recurrent
      infections suggests that cell-mediated immunity may be important in determining
      the duration and severity of the recurrent infection. However, immunosuppression
      may not be the direct mechanism of recrudescence. Lesions were not observed in
      untreated animals, and virus could not be detected in either tissues or
      secretions. However, both lesions and virus were found consistently after
      corticosteroid treatment.

PMID- 4355137
TI  - Immunization of mice with live attenuated encephalomyocarditis virus: local
      immunity and survival.
AB  - Mice were vaccinated with an attenuated encephalomyocarditis (EMC) virus strain
      by the intraperitoneal (i.p.) route and by various ways of respiratory
      administration: aerosol exposure and intratracheal (i.t.) and intranasal (i.n.)
      instillation. A linear relationship was found between vaccine dose and the
      resulting serum antibody titer. The effectiveness of the vaccine was determined
      by measuring the 50% protective doses (ED(50) values) after a lethal challenge
      with live virulent virus given by the i.p. route. For all three methods of
      respiratory immunization essentially the same ED(50) value was found, about 200
      plaqueforming units (PFU), but i.p. immunization was less effective, the ED(50)
      value being about 600 PFU. To investigate the protective effect of local
      immunity, mice were vaccinated i.p. or i.n. and challenged by the i.n. route. The
      same ED(50) values were found as after i.p. challenge, indicating that the degree
      of protection afforded by the vaccine depends only on the route of vaccination
      and not on the route of challenge. This means that protection depends largely on
      systemic immunity and that local immunity plays only a minor role in this system.
      The results are discussed in relation to the feasibility of respiratory
      immunization against animal viruses.

PMID- 4355138
TI  - Immunity against parainfluenza-3 virus in cattle: anti-neuraminidase activity in
      serum and nasal secretion.
AB  - The antigenicity of two parainfluenza=3 virus strains, a "neuraminidasestrong"
      and a "neuraminidase-weak," was compared. For both strains the amount of
      hemagglutinin units was equal. The antibody responses to neuraminidase and
      hemagglutinin were measured on samples of serum and nasal secretion and were
      found to be similar, irrespective of the strain used for immunization. Anti
      neuraminidase activity was demonstrated in the gel phase of nasal secretion of
      immunized cattle. Immunglobulin A was found attached to the peplomers of
      inhibited virus by immuno-electron microscopy.

PMID- 4355139
TI  - Persistent Newcastle disease virus infection in embryonic chicken tracheal organ
      cultures.
AB  - The persistent infection of embryonic chicken tracheal organ cultures with
      Newcastle disease virus (NDV) is described. Tracheal explants remained
      morphologically intact and were able to support the replication of NDV for 6
      months. Peak titers of released virus occurred at 1 week postinfection, whereas
      maximal immunofluorescence was not observed until 30 days postinfection. The
      inoculum titer was not critical, and viral persistence resulted with either of
      two strains of NDV tested. Serum was not required in the medium for explant
      viability or to maintain the persistent infection. The presence of a
      contaminating virus morphologically resembling a leukovirus neither altered the
      course of infection nor affected the survivability of explants. Although
      interferon was not detected in the culture medium, persistently infected explants
      were resistant to heterologous viral challenge, and a similar resistant state
      could be induced in uninfected explants with exogenous interferon or ultraviolet
      light-inactivated NDV. No evidence was found to implicate antibody as a
      regulatory factor in the establishment or maintenance of persistence. The results
      from electron microscopy and immunofluorescence suggest the cells of the
      subepithelial connective tissue as the site of NDV persistence.

PMID- 4355141
TI  - Intracellular measurements in a closed hyperbaric chamber.

PMID- 4355142
TI  - A laboratory program for bioinorganic chemistry.

PMID- 4355140
TI  - Protection of rabbits against local vaccinia virus infection by Brucella abortus
      and polyacrylic acid in the absence of systemic interferon production.
AB  - Brucella abortus and polyacrylic acid, two agents whose interferon-inducing
      capacity in the mouse has been well established, failed to stimulate circulating
      interferon production in rabbits, yet protected rabbits against local vaccinia
      virus infection.

PMID- 4355143
TI  - Alveolar cell carcinoma.

PMID- 4355144
TI  - Drug-albumin interactions using spin labeling.

PMID- 4355145
TI  - Effect of stimulation and acetylcholine on 32P and 14C incorporation into
      phospholipids of eel electroplax.

PMID- 4355146
TI  - The mitochondrial derivative of the spermatozoon of Drosophila before and after
      fertilization.

PMID- 4355147
TI  - Correlations in differentiation of protophloem sieve elements of Allium cepa
      root.

PMID- 4355148
TI  - [Automatic maintenance of muscle relaxation during general anesthesia].

PMID- 4355149
TI  - [Cytochrome oxidase and peroxidase of blood leukocytes in emergency surgery of
      the abdominal cavity].

PMID- 4355150
TI  - Sphingolipid fatty acid composition of rat brain "membranous sacs".

PMID- 4355152
TI  - [Hypoglycemic non-insular digestive tumors].

PMID- 4355151
TI  - Effect of biliary obstruction on canine plasma and biliary lipids.

PMID- 4355154
TI  - Structural analysis of the highly hydrogen bonded B3 fragment of 28S rRNA of
      Novikoff hepatoma ascites cells.

PMID- 4355153
TI  - Letter: Electron microscope autoradiography of kidney after administration of
      210Pb in mice.

PMID- 4355155
TI  - Quantitative distribution of lipids in mouse total liver, mitochondria and
      microsomes.

PMID- 4355156
TI  - Electrophysiological and behavioral effects of electrical stimulation  of the
      raphe nuclei in cats.

PMID- 4355157
TI  - The electroencephalogram of sheep and goats with special reference to rumination.

PMID- 4355158
TI  - Ultrastructure of pig tubal ova. The unfertilized and pronuclear stage.

PMID- 4355159
TI  - Evidence for the existence of serotonin-, dopamine-, and noradrenaline-containing
      neurons in the gut of Lampetra fluviatilis.

PMID- 4355160
TI  - The haemocytes of Calliphora erythrocephala (Meig.) (Diptera).

PMID- 4355161
TI  - The rostral pars distalis of the pituitary gland of the freshwater and marine
      alewife (Alosa pseudoharengus). A light and electron microscope study.

PMID- 4355162
TI  - [An electron microscopic study of degenerating autonomic terminals following
      section of postganglionic fibres (author's transl)].

PMID- 4355163
TI  - The neurohypophysis of the crested newt. 3. Fine structure of the median
      eminence.

PMID- 4355164
TI  - [Morphology and cytochemistry of the Harderian gland of Anatidae (author's
      transl)].

PMID- 4355165
TI  - Age changes in the centrally and peripherally located sensory neurons in rat.

PMID- 4355166
TI  - [The state of adrenal cortical function in chronic alcoholism].

PMID- 4355167
TI  - [Oxidative enzyme activity in the peripheral blood leukocytes of patients with
      nuclear schizophrenia].

PMID- 4355168
TI  - [Nuclear inclusion in the steroid-producing cells of the normal ovary and in the
      ovary of women with Stein-Leventhal syndrome].

PMID- 4355169
TI  - Encephalomyocarditis (EMC) virus infection of the mouse aorta. An ultrastructural
      study.

PMID- 4355170
TI  - Epidemiology of respiratory syncytial virus infection in Washington, D.C. II.
      Infection and disease with respect to age, immunologic status, race and sex.

PMID- 4355171
TI  - Rheumatoid pneumoconiosis. Documentation of onset and pathogenic considerations.

PMID- 4355172
TI  - The relationship of erythromonocytic leukemia to other myeloproliferative
      disorders.

PMID- 4355173
TI  - Renin-angiotensin system during labor: evaluation of renin activity in normal,
      pre-eclamptic, and pre-existing hypertensive patients.

PMID- 4355174
TI  - The role of cortisol in human parturition.

PMID- 4355175
TI  - Effects of hyperosmolality on transmural sodium transport in the toad bladder.

PMID- 4355176
TI  - Ion transport in rabbit ileal mucosa. 3. Effects of catecholamines.

PMID- 4355177
TI  - Ion transport in rabbit ileal mucosa. IV. Bicarbonate secretion.

PMID- 4355179
TI  - Mucosal cyclic AMP and secretion in the dog stomach.

PMID- 4355178
TI  - Effects of caffeine on neuromuscular transmission in the rat.

PMID- 4355180
TI  - Ornithine decarboxylase stimulation by 3',5'-cyclic AMP in oviduct of Coturnix
      quail.

PMID- 4355181
TI  - Phosphorylase, calcium, and cyclic AMP in smooth-muscle contraction.

PMID- 4355182
TI  - Carcinoma in pleomorphic adenomas of salivary glands.

PMID- 4355183
TI  - The effects of protein synthesis inhibition on sleep in mice.

PMID- 4355184
TI  - The relationship of REM sleep with learning and memory in mice.

PMID- 4355185
TI  - Skin window macrophages in malignant lymphomas.

PMID- 4355186
TI  - Glucose-mediated insulin release: 3',5' cAMP phosphodiesterase.

PMID- 4355187
TI  - Insulin and insulinlike activity in extracts of tumors associated with
      hypoglycemia.

PMID- 4355188
TI  - Propanidid (Epontol)--a new activation method in electroencephalography.

PMID- 4355189
TI  - Studies of the habenulo-interpeduncular pathway in cats.

PMID- 4355191
TI  - Concerning recurrent collaterals and afferent fibers in the hypoglossal nerve of
      the rat.

PMID- 4355192
TI  - Stature and aging.

PMID- 4355190
TI  - Enzymes of cholesterol ester metabolism in the brain of mutant mice, quaking and
      jimpy.

PMID- 4355193
TI  - The equilibrium constants of the adenosine triphosphate hydrolysis and the
      adenosine triphosphate-citrate lyase reactions.

PMID- 4355194
TI  - Characteristics of a soluble gonadotropin receptor from the rat testis.

PMID- 4355196
TI  - Adenosine cyclic 3':5'-monophosphate-mediated transport of neutral and dibasic
      amino acids in jejunal mucosa.

PMID- 4355195
TI  - The 3'-terminal heptanucleotide sequence of the l strand of T7 deoxyribonucleic
      acid.

PMID- 4355197
TI  - Isolation of a disulfide-stabilized, three-chain polypeptide fragment unique to
      the precursor of human collagen.

PMID- 4355198
TI  - Partial purification and characterization of nicotinamide adenine dinucleotide
      kinase from sea urchin eggs.

PMID- 4355199
TI  - Selective acylation of 1-acylglycerophosphorylinositol by rat brain microsomes.
      Comparison with 1-acylglycerophosphorylcholine.

PMID- 4355200
TI  - Oligomycin resistance of mitochondrial adenosine triphosphatase in a pleiotropic
      chromosomal mutant of a "petite-negative" yeast, Schizosaccharomyces pombe.

PMID- 4355201
TI  - An effect of insulin on cyclic adenosine 3':5'-monophosphate phosphodiesterase
      activity in fat cells.

PMID- 4355202
TI  - Regulation of glutamate metabolism and interactions with the citric acid cycle in
      rat heart mitochondria.

PMID- 4355203
TI  - Substrate-induced difference spectral, electron paramagnetic resonance, and
      enzymatic properties of cholesterol-depleted mitochondrial cytochrome P-450 of
      bovine adrenal cortex.

PMID- 4355204
TI  - Steroid metabolism by adult rat adrenocortical cells in monolayer culture.

PMID- 4355205
TI  - Oestrogen receptors in the mammary gland of the lactating rat.

PMID- 4355206
TI  - Mechanism of oestradiol action on the rat uterus: independence of cyclic AMP,
      prostaglandin E2 and beta-adrenergic mediation.

PMID- 4355207
TI  - Intrinsic stimulatory action of follicle-stimulating hormone on ovarian adenylate
      cyclase.

PMID- 4355208
TI  - Evaluation of the efficacy of ascorbic acid in prophylaxis of induced rhinovirus
      44 infection in man.

PMID- 4355210
TI  - Absence of relationship of fecal Clostridium perfringens to rheumatoid arthritis
      and rheumatoid variants.

PMID- 4355209
TI  - Bactericidal antibody in serum during infection with Bordetalla pertussis.

PMID- 4355211
TI  - Glutamate-mediated respiration in tumors.

PMID- 4355212
TI  - Pathology of intestinal neoplasms and other lesions in rats exposed to
      azoxymethane.

PMID- 4355213
TI  - Brief communication: carcinoembryonic antigen in colon cancer: absence in
      perchloric acid precipitates of plasma.

PMID- 4355214
TI  - Brief communication: antigenic relationship between Mycobacterium bovis (BCG) and
      a guinea pig hepatoma.

PMID- 4355215
TI  - Clinical and laboratory investigations on man: systemic administration of potent
      interferon to man.

PMID- 4355216
TI  - Freeze-etching, scanning, and thin-section electron microscopic studies of the
      "hairy" leukocytes in leukemic reticuloendotheliosis.

PMID- 4355217
TI  - Difference in heat stability of antigens associated with Epstein-Barr virus,
      demonstrated by immunodiffusion.

PMID- 4355218
TI  - Expression of malignancy in interspecies Chinese hamster X mouse cell hybrids.

PMID- 4355219
TI  - Pathogenesis of feline viral fibrosarcomas: dose and age effects.

PMID- 4355220
TI  - A possibility of distinction between normal and neoplastic cells through
      transplantation into chick blastoderms.

PMID- 4355221
TI  - Protective effect of the double-stranded polyribonucleotide, polyinosinic
      polycytidylic acid, against rat erythroblastosis induced by murine
      erythroblastosis virus.

PMID- 4355222
TI  - Cell-associated virions and nucleoids of a murine leukemia virus.

PMID- 4355223
TI  - Tumorigenicity and antigenicity of mouse cells infected with Simian virus 40. I.
      Relationship of growth in vitro and in vivo in immunosuppressed and
      immunocompetent recipients.

PMID- 4355224
TI  - Nonimmune rosette formation by lymphoma and leukemia cells from Herpesvirus
      saimiri-infected owl monkeys.

PMID- 4355225
TI  - Oncogenic Marek's disease herpesvirus in avian encephalitis (temporary
      paralysis).

PMID- 4355226
TI  - Tumors in CF-1 mice exposed for six consecutive generations to DDT.

PMID- 4355227
TI  - Tumors of the kidneys, synovia, exocrine pancreas and nasal cavity in BALB-cf-Cd
      mice.

PMID- 4355228
TI  - Granular cell myoblastoma occurring in the lower lip.

PMID- 4355229
TI  - Alphafetoprotein in testicular tumors.

PMID- 4355231
TI  - How mercurial diuretics work.

PMID- 4355230
TI  - The mineral content of inguinal nodes in barefoot people with and without
      elephantiasis of the legs.

PMID- 4355232
TI  - Parathyroid hormone secretion in familial vitamin-D-resistant rickets.

PMID- 4355233
TI  - Thermal synthesis of amino acids from a simulated primitive atmosphere.

PMID- 4355234
TI  - Specific neutralization of human hepatitis type A in marmoset monkeys.

PMID- 4355235
TI  - Transformation of mammalian cells in vitro by low doses of X-rays.

PMID- 4355236
TI  - Acetylcholine release within the cat striatum during the sleep-wakefulness cycle.

PMID- 4355237
TI  - Complementation analysis of maple syrup urine disease in heterokaryons derived
      from cultured human fibroblasts.

PMID- 4355238
TI  - Role of inositol cyclic phosphate in stimulated tissues.

PMID- 4355239
TI  - Letter: Accelerated substrate cycling of fructose-6-phosphate in the muscle of
      malignant hyperthermic pigs.

PMID- 4355240
TI  - Renin in anesthetized rats.

PMID- 4355242
TI  - Morphologically "differentiated" mouse neuroblastoma cells induced by noncyclic
      AMP agents: levels of cyclic AMP, nucleic acid and protein.

PMID- 4355241
TI  - Analysis of tremorgenic effects of intracaudate serotonin.

PMID- 4355243
TI  - The selective inhibition of secondary IgE antibody response in mice by dibutyryl
      adenosine 3',5'-cyclic monophosphoric acid and theophylline.

PMID- 4355244
TI  - Maturity of the pituitary-adrenal axis in the newborn dog.

PMID- 4355245
TI  - Effects of urethane on pituitary-adrenal function in the rat.

PMID- 4355246
TI  - Induction of immunity in man by crystalline adenovirus type 5 capsid antigens.

PMID- 4355247
TI  - Maternal-fetal endocrine interrelations in the rat: effects of cyclic and
      dibutyryl cyclic AMP on pituitary-thyroid and adrenocortical systems in mother
      and neonate.

PMID- 4355248
TI  - Sites of x-irradiation-induced damage in the microsomal drug metabolizing enzyme
      system of rat liver during development.

PMID- 4355249
TI  - Correspondence: On the ESR spectra of radicals produced by the reaction of OH
      with uracils.

PMID- 4355250
TI  - A semiempirical study of the sugar radicals in irradiated cytidylic acid b and
      deoxyadenosine.

PMID- 4355251
TI  - [The hydrochemical living conditions of the immature stages of Boophthora
      erythrocephala De Geer (Diptera, Simuliidae). 2. Development of a technique for
      rearing under experimental conditions (author's transl)].

PMID- 4355252
TI  - Invasive mole and gestational choriocarcinoma in Denmark, 1940-1969. Biological
      and clinical aspects.

PMID- 4355253
TI  - Primary hepatic tumors in infancy and childhood.

PMID- 4355255
TI  - Successfully treated postoperative Candida parakrusei endophthalmitis.

PMID- 4355256
TI  - Malignant tumors of the submaxillary gland.

PMID- 4355254
TI  - Entrapment of ophthalmic ointment in the cornea.

PMID- 4355257
TI  - Juvenile angiofibroma. Review of 120 cases.

PMID- 4355258
TI  - Current surgical management of functioning islet cell tumors of the pancreas.

PMID- 4355259
TI  - Airborne stability of simian virus 40.
AB  - The influence of relative humidity on the airborne survival of simian virus 40
      (SV40) was studied by allowing virus aerosols to age in rotating drums at 21 or
      32 C and at a relative humidity (RH) value ranging from 22 to 88%. Airborne SV40
      virus was stable at every RH tested at 21 C, but aerosols maintained at 32 C were
      inactivated within 60 min at mid-range RH values. The unusual stability at 21 C
      over a broad RH range indicates that potentially biohazardous situations may
      occur under laboratory conditions if this virus becomes accidentally airborne.

PMID- 4355260
TI  - Filtration methods for recovering enteroviruses from foods.
AB  - A set of simple, rapid filtration methods has been developed for recovering
      enteroviruses from foods. The methods employ quite inexpensive equipment, and the
      resulting extract might be concentrated in any of several ways. Three model
      enteroviruses were apparently recovered with at least 80% efficiency when
      inoculated, at levels ranging from thousands to one plaque-forming unit per 20-g
      sample, into eleven foods representing six major food groups.

PMID- 4355262
TI  - Influence of parabiosis on tumour growth in tumour bearing animals.

PMID- 4355261
TI  - Mass airflow cabinet for control of airborne infection of laboratory rodents.
AB  - A mass airflow cabinet for handling and housing of laboratory rodents has been
      developed and tested. The unit consists of a high-efficiency particulate air
      filter and uniform distribution of air at a vertical velocity of 19 cm per s.
      Animals are maintained without bedding in mesh-bottomed cages that rest on
      rollers for rotation inside the cabinet. There is an air barrier of 90 cm per s
      separating the cabinet air from room air. Sampling for airborne bacteria yielded
      an average of 0.03 colony-forming units (CFU) per ft(3) of air inside the
      cabinet, whereas 28.8 CFU per ft(3) was simultaneously detected outside the
      cabinet during housekeeping, a reduction of almost three logs. The efficiency of
      the air barrier was tested by aerosolization of T3 phage. When phage was
      aerosolized 5 cm outside the cabinet, no phage could be detected 5 cm inside when
      the fans were operating; with the fans off an average of 1.6 x 10(4) plaque
      forming units (PFU) per ft(3) was detected in six tests. Aerosolization of phage
      inside the cabinet yielded an average of 9 x 10 PFU per ft(3) outside; an average
      of 4.1 x 10(6) PFU per ft(3) were detected with the fans not in operation, a
      reduction of more than four logs. In-use studies on effectiveness showed that the
      cabinet significantly reduced the incidence of mice originally titer-free to Reo
      3 virus. Hemagglutination inhibition antibodies to Reo-3 were detected in 9/22
      (42%) mice housed in a conventionally ventilated animal laboratory while no
      seroconversion was detected in any of 22 mice housed in the mass air flow cabinet
      in the same laboratory.

PMID- 4355263
TI  - Herpes zoster myelitis. Evidence for viral invasion of spinal cord.

PMID- 4355264
TI  - Asbestos-induced intrathoracic tissue reactions.

PMID- 4355265
TI  - Cytomegalovirus vasculitis with fatal colonic hemorrhage.

PMID- 4355266
TI  - An ESR study of the active-site conformations of free and immobilized trypsin.

PMID- 4355267
TI  - EPR study of nitric oxide-treated reduced ceruloplasmin.

PMID- 4355268
TI  - Arabinose (fucose) dehydrogenase from pig liver. I. Isolation and
      characterization.

PMID- 4355269
TI  - Multiple forms of adenosine 3',5'-cyclic monophosphate-dependent protein kinase
      from monkey skin.

PMID- 4355270
TI  - Cellular reaction in trophoblastic tumours.
AB  - The presence of a mononuclear cell reaction to 41 gestational choriocarcinomata,
      10 invasive moles and 13 malignant trophoblastic teratomata has been
      investigated. The intensity of the reaction was graded; there was a significantly
      better response to therapy and survival rate in those with a "severe" cellular
      reaction than in those with a "mild" reaction to gestational choriocarcinoma. The
      pathological and clinical features of invasive moles showed no relationship with
      the cellular reaction to the tumour. The cellular reaction to trophoblastic
      teratomata was generally poor but there was a marked cellular reaction to the
      tumour of one patient who has enjoyed a sustained remission.The relationship of
      cellular reaction and response to treatment with other histological and clinical
      features was examined. With the exception of a positive correlation between the
      degree of vascular invasion and response to treatment, none was found.It is
      suggested that an infiltrate of mononuclear cells in gestational choriocarcinoma
      is probably a response to the presence of tumour antigens. The infiltrate
      favourably affects the response to chemotherapeutic agents, suggesting that it
      contributes to tumour cell death and it may be interpreted as an immunological
      response directed at tumour rejection.

PMID- 4355271
TI  - Some EPR signals in tumour tissue.
AB  - Normal and tumour tissues from rats, blood from normal and tumour bearing rats,
      and normal human blood were examined using the electron paramagnetic resonance
      (epr) technique. At low temperature a triplet epr signal, which is known to be
      produced by a NO-haemoprotein complex, was detected in some tumour samples and in
      decaying normal liver. At room temperature all of the tumour samples examined
      gave a doublet signal. This signal was also detected in blood but not in other
      normal tissues. The signal has a g value of 2.0054 +/- 0.0002 and a hyperfine
      splitting of 1.80 +/- 0.05 G and is assigned to the ascorbyl free radical. Model
      experiments suggest that the appearance of detectable concentrations of this
      radical result from a disturbance of the normal state of the ascorbic acid,
      dehydroascorbic acid redox system. It was verified that cell division is not
      responsible for the ascorbyl radical although autolysis may be involved. A
      possible relationship between the formation of ascorbyl radicals and other
      paramagnetic species in tumours is discussed.

PMID- 4355272
TI  - The effect of nociceptive cutaneous stimuli on human motoneurons.

PMID- 4355274
TI  - Radiotherapy for suspected lung cancer not proved by tissue diagnosis.

PMID- 4355273
TI  - Immunologic status in lung cancer.

PMID- 4355275
TI  - Type 4 hyperlipoproteinemia: one theory of atherogenesis.

PMID- 4355276
TI  - Neuro-endocrine correlates of immune response. I. Effects of brain lesions on
      antibody production, Arthus reactivity and delayed hypersensitivity in the rat.

PMID- 4355277
TI  - Studies with two new phosphodiesterase inhibitors (ICI 58, 301 and ICI 63, 197)
      on anaphylaxis in guinea pigs, mice and rats.

PMID- 4355278
TI  - Differentiation of T cells induced by preparations from thymus and by nonthymic
      agents.

PMID- 4355279
TI  - Lymphocyte activation in subacute sclerosing panencephalitis virus and
      cytomegalovirus infections. In vitro stimulation in response to viral-infected
      cell lines.
AB  - Efforts to stimulate lymphocytes from measles seropositive and two patients with
      subacute sclerosing panencephalitis (SSPE) with either commercially available
      measles virus or virus isolated from a known case of SSPE failed to show any
      significant data using a microculture assay. Similar results were obtained using
      lymphocytes from two patients with active cytomegalovirus (CMV) infections and
      CMV seropositive individuals using CMV suspensions. On the other hand,
      lymphocytes from the patients with subacute sclerosing panencephalitis exhibited
      in vitro blastogenesis in culture with SSPE virus-infected HeLa cells. Similarly,
      lymphocytes from the CMV-infected patients demonstrated blastogenesis when
      cocultivated with CMV-infected WI-38 cells. This affords a new method for
      determining the cell-mediated immune capacity of patients with "slow" virus
      diseases.

PMID- 4355280
TI  - Studies on membrane-bound receptors for antigen. Preparation of populations of
      receptor-depleted lymphocytes.
AB  - THE EFFECT OF POLYADENYLIC: polyundylic acid complexes (poly A:U) on the amount
      of antibody on the surface of various populations of mouse lymphoid cells has
      been investigated by means of a sensitive measure of such activity-the binding by
      primed cell populations of beta-galactosidase (betaGZ) as an antigen. The
      sensitivity derives from the liberation of fluorescein from an artificial
      substrate, fluorescein-di-beta-galactopyranoside (FDbetaG). After incubation with
      100 ng/ml of poly A:U, only 40% of the cells previously showing antigen-binding
      were still active. The optimum range of activity lay between 0.01-1.0 microg/ml
      poly A:U. Such cells showed increased RNA and protein synthesis as indicated by
      [(3)H]uridine and [(14)C]amino acid incorporation. The polynucleotide effect was
      abolished by incubation of the cells with sodium azide or iodoacetate, but not by
      puromycin. When the proteins on the cell surface were labeled by (125)I, poly A:U
      caused their release into the medium. Reports by others that the enhancing effect
      of polynucleotides on the immune response involves the adenylcyclase system are
      consistent with the finding reported here that reduction of binding by dibutryl
      5'-cyclic monophosphoric acid (cAMP) and poly A:U were parallel in extent, and
      that theophylline and poly A:U acted synergistically in suboptimal concentrations
      of each.

PMID- 4355281
TI  - Varicella-zoster virus.

PMID- 4355282
TI  - Experimental human reinfection with herpes simplex virus.

PMID- 4355283
TI  - The significance of surface changes in parakeratotic horn.

PMID- 4355284
TI  - Early response of lymph node cells to Abelson leukemia virus.

PMID- 4355285
TI  - Hexachlorophene neuropathy in rats.

PMID- 4355286
TI  - Induced protein synthesis and oestradiol binding to the nuclei in the rat uterus.

PMID- 4355288
TI  - [Genesis and prognostic significance of juvenile hypercorticism].

PMID- 4355287
TI  - Trophic influences of the nervous system: their biochemical basis and disturbance
      in skeletal muscle.

PMID- 4355290
TI  - Ultrastructure of the gonadal wall of the sea cucumber, Leptosynapta clarki
      (Echinodermata: Holothuroidea).

PMID- 4355289
TI  - Cytology and cytochemistry of the scolex gland cells in Diphyllobothrium ditremum
      (Creplin, 1825).

PMID- 4355291
TI  - The granule-containing cell somata in the superior cervical ganglion of the rat,
      as studied by a serial sampling method for electron microscopy.

PMID- 4355293
TI  - On structural patterns of the lamina propria of human seminiferous tubules.

PMID- 4355294
TI  - [Posterior lacerate foramen].

PMID- 4355292
TI  - Electron microscopic identification of several types of endocrine cells in the
      bronchial epithelium of human foetuses.

PMID- 4355295
TI  - The development of a comprehensive treatment programme. Experiences from the
      after-care service of a mental hospital.

PMID- 4355296
TI  - Effects of repeated simulated sonic booms of 1.0 PSF on the sleep behavior of
      young and old subjects.

PMID- 4355297
TI  - Vestibular ototoxicity in primates.

PMID- 4355299
TI  - Quantitation of three subpopulations of human serum very low density
      lipoproteins.

PMID- 4355300
TI  - Practical considerations in angiotensin II antibody production.

PMID- 4355298
TI  - Inner ear concentrations and ototoxicity of different antibiotics in local and
      systemic application.

PMID- 4355301
TI  - Functional and structural changes in liver mitochondria of rats due to CC14
      intoxication. I. Studies on state of electron-transport chain.

PMID- 4355302
TI  - Functional and structural changes in liver mitochondria of rats due to CCl4
      intoxication. II. Respiratory chain and ion transport.

PMID- 4355303
TI  - Some biochemical and pharmacological actions of (-) erythro-meta-(meta
      chlorobenzyloxy)-2-(1-aminoethyl)-benzyl alcohol. A derivative of metaraminol.

PMID- 4355304
TI  - Bradykinin potentiating peptide PCA-Lys-Trp-Ala-Pro. An inhibitor of the
      pulmonary inactivation of bradykinin and conversion of angiotensin I to II.

PMID- 4355305
TI  - Spectrophotometric assay and properties of the angiotensin-converting enzyme of
      rabbit lung.

PMID- 4355306
TI  - Effect of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane on
      adrenocorticotropic hormone-induced steroidogenesis in various preparations in
      vitro of dog adrenal cortex.

PMID- 4355307
TI  - Effect of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane in vivo on
      baseline and adrenocorticotropic hormone-induced steroid production in dog
      adrenal slices.

PMID- 4355308
TI  - Chemical and structural relationships of NAD+ and platinum binding to malate
      dehydrogenase.

PMID- 4355309
TI  - Ferredoxin from Veillonella alcalescens.

PMID- 4355310
TI  - Determination of the zero-field splitting in human acid methemoglobin by
      millimeter and submillimeter ESR experiments.

PMID- 4355311
TI  - Evaluation of dipolar nuclear magnetic resonance shifts in low-spin hemin
      systems: ferricytochrome c and metmyoglobin cyanide.

PMID- 4355313
TI  - [Letter: Hyperemesis gravidarum].

PMID- 4355312
TI  - [Acts of violence commited by mentally deranged persons (author's transl)].

PMID- 4355314
TI  - Chemical modification of Ehrlich ascites tumour cells by periodate and succinic
      anhydride: effects on metabolism and membrane permeability.

PMID- 4355315
TI  - Amino acid dependent ATP-32PPi exchange measurement. A filter paper disk method.

PMID- 4355316
TI  - Light induced H+ uptake catalysed by photochemical reaction centres from
      Rhodopseudomonas spheroides R26.

PMID- 4355317
TI  - Separation of the isoenzymes of lactate dehydrogenase by affinity chromatography
      using an immobilized AMP-analogue.

PMID- 4355318
TI  - Synthesis of antibiotics by enzymes from altered growth conditions by Bacillus
      licheniformis.

PMID- 4355319
TI  - Purification of estradiol receptor by affinity chromatography. Representative
      experiments.

PMID- 4355320
TI  - Spin-spin interaction between iminoxyl radicals localised in antibody combining
      sites.

PMID- 4355321
TI  - Extrachromosomal element delta in Drosophila melanogaster. IX. Induction of delta
      retaining chromosome lines by mutation and gene mapping.
AB  - [Delta b], symbolized as [delta(b)], is retained by S(b) chromosome lines and
      transmitted through the females to their progeny. Transmission through the males
      is not directly demonstrable (Minamori 1969a). [delta r], symbolized as
      [delta(r)], is retained by S(r) chromosome lines and transmitted biparentally
      (Minamori 1971). The multiplication of delta is suppressed at low temperature.
      All descendant lines derived from S(b)-carrying or S(r)-carrying flies in which
      the presence of delta cannot be demonstrated gradually accumulate their specific
      delta factors over many generations (Minamori 1969b, 1972). The delta factors and
      the sensitive chromosomes are inseparably associated. This observation led to the
      assumption that delta may be a copy of a chromosomal gene or a certain agent
      integrated into the chromosome (Minamori 1972). This assumption was examined in
      the present study by experiments designed to induce delta-retaining sensitive
      chromosomes, and to map the gene(s) responsible for delta-retention and/or for
      sensitivity to the killing action of delta factor. One sensitive chromosome which
      retained [delta(b)] (S(b) chromosome) was obtained in the presence of [delta(b)]
      out of 2492 insensitive chromosomes which retained no delta; in addition one S(b)
      chromosome was obtained in the presence of [delta(r)] out of 2131 insensitives.
      The latter finding suggests that S(b) might be induced by a mutation caused by
      [delta(b)] or [delta(r)], but not by integration of either delta into the
      chromosome. Four S(b) chromosomes and one sensitive chromosome which retained
      [delta(r)] (S(r) chromosome) were obtained out of 1970 insensitives when males
      carrying the chromosome were fed an alkylating mutagen, ethyl methane sulfonate
      (EMS). The location of delta-retaining genes was examined by crossing-over
      experiments employing eight S(b) and five S(r) chromosomes. The genes on these
      chromosomes were found to be located in the same region or near one another. The
      gene for [delta(b)], symbolized as Da(b), and the gene for [delta(r)], symbolized
      as Da(r), are assumed to be multiple alleles of a locus at 2-24.9. The
      sensitivity of the chromosomes was modified appreciably by recombination; hence,
      the genes controlling this trait are assumed to be a polygenic system. The
      findings obtained in this study lead to the hypothesis that delta may be produced
      by a chromosomal gene (Da) and transmitted extrachromosomally.

PMID- 4355322
TI  - Temperature-sensitive mutations in Drosophila melanogaster. XVII. Heat- and cold
      sensitive lethals on chromosome 3.
AB  - Ethyl methanesulfonate-treated third chromosome of Drosophila melanogaster were
      tested for the presence of dominant and recessive temperature-sensitive lethal
      mutations at 17 degrees , 22 degrees and 29 degrees C. Out of 1,176 chromosomes
      tested, no dominant ts lethals, 21 heat-sensitive, 22 cold-sensitive and 10 heat
      cold-sensitive lethals were recovered. Heat-cold sensitivity was produced by a
      single mutation in all cases. Sixty-two percent of the ts lethals were fertile as
      homozygotes in both sexes. Surprisingly, 88% of the ts lethals mapped between st
      and Sb, a region straddling the centromere and estimated to comprise 12.9% of the
      genetic length and 55% of the physical length of chromosome 3. All but one of the
      heat- and cold-sensitive lethals complemented with each other at their respective
      restrictive temperatures.

PMID- 4355323
TI  - Xeroradiography of the breast.

PMID- 4355324
TI  - Observations on the intranasal vaccination of pregnant cattle against infectious
      bovine rhinotracheitis and parainfluenza-3 virus infection.

PMID- 4355325
TI  - Separation and identification of food dyes. V. Examination of ponceau 6R dyes:
      extraction of dyes from confectionery products (cakes, cake mixtures and
      pastries).

PMID- 4355326
TI  - The tract of Lissauer in relation to sensory transmission in the dorsal horn of
      spinal cord in the macaque monkey.

PMID- 4355327
TI  - The interaction between Mycoplasma hominis and poliovirus in cell culture.

PMID- 4355328
TI  - Comparison of the aerosol stabilities of foot-and-mouth disease virus suspended
      in cell culture fluid or natural fluids.

PMID- 4355329
TI  - Natural selection of mutants of vesicular stomatitis virus by cultured cells of
      Drosophila melanogaster.

PMID- 4355330
TI  - The fragmentation of cellular DNA and the formation of pseudovirions during SV 40
      infection of African green monkey kidney cells.

PMID- 4355331
TI  - Isolation and characterization of virus-resistant mouse embryo fibroblasts.

PMID- 4355333
TI  - Evaluation of the methods of differentiation of variola and alastrim viruses.

PMID- 4355332
TI  - Concentration of Epstein-Barr virus from cell culture fluids with polyethylene
      glycol.

PMID- 4355334
TI  - Results of a virological study of smallpox convalescents and contacts: short
      communication.

PMID- 4355336
TI  - Large-scale production of clostridial collagenase and lecithinase C: short
      communication.

PMID- 4355335
TI  - Serological types of whooping cough bacteria and their connection with immunity
      in vaccinated children.

PMID- 4355337
TI  - Distribution and relationship of precursor Z material to organizing myofibrillar
      bundles in embryonic rat and hamster ventricular myocytes.

PMID- 4355338
TI  - Glycolytic and tricarboxylic acid cycle intermediates during cardiac arrest and
      recovery in eu-, hyper- and hypothyroid rats.

PMID- 4355339
TI  - Abrupt reoxygenation of the anoxic potassium-arrested perfused rat heart: a study
      of myocardial enzyme release.

PMID- 4355340
TI  - The S-100 protein in water-soluble and pentanol-extractable form in normal human
      brain and tumours of the human nervous system. A quantitative study.

PMID- 4355341
TI  - [Morphological immunological studies on histogenesis of experimental brain
      tumors].

PMID- 4355342
TI  - Hallervorden-Spatz disease and infantile neuroaxonal dystrophy. Ultrastructural
      observations, anatomical pathology and nosology.

PMID- 4355343
TI  - Sporadic acrodystrophic neuropathy.

PMID- 4355344
TI  - Interaction of mouse strain and differential housing upon resistance to
      Plasmodium berghei.

PMID- 4355345
TI  - A radioimmunoassay of the antigen-binding capacity of rabbit antiserum prepared
      with axenically grown Entamoeba histolytica, Laredo strain.

PMID- 4355346
TI  - The effect of beta-lipoprotein on antistreptolysin-O antibody titers.

PMID- 4355347
TI  - Interaction of isonicotinoyl hydrazide-adenine-dinucleotide with dehydrogenases.

PMID- 4355349
TI  - International symposium on Hodgkin's disease. Session 2. Histopathology and
      experimental cytology. Invited discussion: Synthesis and implications for the
      etiology, pathogenesis and spread of Hodgkin's disease.

PMID- 4355348
TI  - The activity of some nitroso compounds in the mouse dominant-lethal mutation
      assay. I. Activity of N-nitroso-N-methylurea, N-methyl-N-nitroso-N'
      nitroguanidine and N-nitrosomorpholine.

PMID- 4355350
TI  - Oncogenic herpesviruses: a selective review and their possible inplications for
      Hodgkin's disease.

PMID- 4355351
TI  - Is Epstein-Barr virus a human tumor virus?

PMID- 4355352
TI  - International Symposium on Hodgkin's Disease. Session 1. Epidemiology and
      etiology. Part 2. Virology and serology--new approaches to identification of an
      etiologic agent.

PMID- 4355353
TI  - Epstein-Barr virus-related serology in Hodgkin's disease.

PMID- 4355354
TI  - Invited discussion: relationship of titers of Epstein-Barr virus to cell-mediated
      immunity in patients with Hodgkin's disease.

PMID- 4355355
TI  - [Importance of sensory nerve action potentials examination in traction injuries
      of brachial plexus roots].

PMID- 4355356
TI  - Burkitt's lymphoma and heredity.

PMID- 4355357
TI  - Evaluation of the hand and its function.

PMID- 4355358
TI  - Rehabilitation of the hand with motor and sensory impairment.

PMID- 4355360
TI  - Freeze-etching electron microscopy of the lung.

PMID- 4355359
TI  - The place of microsurgery in hand surgery.

PMID- 4355361
TI  - Endometrial cancer. Facts and theories.

PMID- 4355362
TI  - Pediatric familial type II hyperlipoproteinemia: therapy with diet and
      cholestyramine resin.

PMID- 4355363
TI  - California arbovirus (La Crosse) infections. I. Clinical and laboratory findings
      in 66 children with meningoencephalitis.

PMID- 4355364
TI  - Stimulation of steroid secretion in adrenal tumor cells by choleragen.
AB  - Choleragen, the pure protein from cholera toxin, stimulates steroid secretion by
      Y-1 adrenal tumor cells in culture. The secreted steroids are the same as seen
      after addition of adrenocorticotropic hormone. Half-maximal stimulation occurs at
      15 pM; stimulation is essentially irreversible by washing and partially
      reversible (for about 1 hr) by antibody, and there is a latent period of about 60
      min before stimulation is seen. Stimulation of adenylate cyclase occurs at about
      30-fold higher choleragen concentrations. Gangliosides inhibit choleragen
      stimulation when added before but not after the toxin. Lipopolysaccharides from
      Escherichia coli, Salmonella typhosa, and Serratia marcescens also stimulate
      steroid secretion, but are less potent than choleragen.

PMID- 4355366
TI  - Familial hypercholesterolemia: identification of a defect in the regulation of 3
      hydroxy-3-methylglutaryl coenzyme A reductase activity associated with
      overproduction of cholesterol.
AB  - The homozygous form of the autosomal dominant disorder, familial
      hypercholesterolemia, is characterized by the presence in children of profound
      hypercholesterolemia, cutaneous planar xanthomas, and rapidly progressive
      coronary vascular disease that usually results in death before age 30 years.
      Cultured skin fibroblasts from three unrelated subjects with this disorder showed
      40- to 60-fold higher activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase
      (EC 1.1.1.34), the rate-controlling enzyme in cholesterol biosynthesis, when
      compared with fibroblasts of seven control subjects. Enhanced enzyme activity
      resulted from a complete absence of normal feedback suppression by low-density
      lipoproteins, which led to a marked overproduction of cholesterol by the mutant
      cells. The demonstration of apparently identical kinetic properties of the
      reductase activity of control and mutant cells, coupled with the evidence that
      this enzyme is normally regulated not by allosteric effectors but by alterations
      in enzyme synthesis and degradation, suggests that the primary genetic
      abnormality does not involve the structural gene for the enzyme itself, but a
      hitherto unidentified gene whose product is necessary for mediation of feedback
      control by lipoproteins. The fibroblasts of two obligate heterozygotes, the
      parents of one of the homozygotes, showed a pattern of enzyme regulation
      intermediate between that of controls and homozygotes.

PMID- 4355365
TI  - Specific recognition of plasma membranes by embryonic cells.
AB  - Methods have been developed for preparation of plasma membrane fractions from
      embryonic neural retina and cerebellum. These membrane fractions are specifically
      bound by intact cells of the original tissue (homotypic binding) and not by cells
      from the other tissue (heterotypic binding). Aggregation of neural retina cells
      and cerebellar cells is prevented by addition of homotypic membranes but not by
      heterotypic membranes. We conclude that, under our assay conditions, these
      embryonic cells specifically recognize homotypic membranes, and that the
      specificity of recognition is the same as in the initial step in the process of
      cellular aggregation.

PMID- 4355367
TI  - Prediction of the amount of secondary structure in a globular protein from its
      aminoacid composition.
AB  - Multiple regression is used to obtain relationships for predicting the amount of
      secondary structure in a protein molecule from a knowledge of its aminoacid
      composition. We tested these relations using 18 proteins of known structure, but
      omitting the protein to be predicted. Independent predictions were made for the
      two subchains of hemoglobin and insulin. The average errors for these 20 chains
      or subchains are: helix +/- 7.1%, beta-sheet +/- 6.9%, turn +/- 4.2%, and coil +/
      5.7%. A second set of relations yielding somewhat inferior predictions is given
      for the case in which Asp and Asn, and Glu and Gln, are not differentiated.
      Predictions are also listed for 15 proteins for which the aminoacid sequence or
      tertiary structure is unknown.

PMID- 4355368
TI  - Methionine transfer ribonucleic acids of avian myeloblastosis virus.
AB  - Chick-embryo cells contain four isoaccepting species of methionine transfer RNA
      (I-IV). One species (I) is the initiator, tRNA(f) (Met), and the others (II, III,
      and IV) are the donors of internal methionyl residues (tRNA(m) (Met)). Over 85%
      of the tRNA(Met) in purified avian myeloblastosis virus consists of one tRNA(m)
      (Met) species, which resembles host-cell tRNA(Met) IV with respect to
      chromatographic properties on RPC-5, electrophoretic mobility of the terminal
      methionyl-oligonucleotide, and activity in cell-free protein synthesis in
      response to synthetic and natural messenger RNAs. Thus, tRNA(Met) IV of avian
      myeloblastosis virus is structurally indistinguishable from the corresponding
      host-cell species, and, although not involved in initiation of viral protein
      synthesis, is able to function in peptide-chain elongation.

PMID- 4355369
TI  - ATPase and GTPase activities associated with a specific 5S RNA-protein complex.
AB  - An RNA-protein complex consisting of 5S RNA and two ribosomal proteins, B-L5 and
      B-L22, was isolated from Bacillus stearothermophilus ribosomes and found to be
      active in GTP hydrolysis. This activity was not influenced by elongation factor
      G. Further analysis of this complex showed that it was also able to hydrolyze
      ATP. Inhibition studies revealed that ATP was a noncompetitive inhibitor of GTP
      and that GTP was also a noncompetitive inhibitor of ATP, indicating that two
      different enzymatic sites were involved. Differences in pH optimum and optimal
      temperature also point to a twosite enzyme complex. Both enzymatic hydrolyses
      were inhibited by thiostrepton and fusidic acid, which are known inhibitors of
      protein synthesis.

PMID- 4355370
TI  - Isolation of circular DNA molecules from whole cellular DNA by use of ATP
      dependent deoxyribonuclease.
AB  - A technique is described for isolation of plasmid DNA in closed and open circular
      double-stranded forms from bacterial cells, by use of ATP-dependent
      deoxyribonuclease purified from Micrococcus luteus. This DNase, acting only upon
      linear DNA molecules, degrades all bacterial chromosomal DNA extracted in the
      linear form. Circular plasmid DNAs are left intact, and are then separated by
      sedimentation through a sucrose gradient. Unlike previous techniques for analysis
      of plasmid DNA, this technique can be used to isolate not only closed circular
      DNA but also open circular DNA. Several plasmids, such as those from phage
      (lambdadv1 and lambdadv21), a colicinogenic factor (Col E2), a sex factor (F(8)'
      gal), and "minicircles" in Escherichia coli 15, in both the open and closed
      circular forms, were well separated from chromosomal DNA by this technique.

PMID- 4355371
TI  - Linear association between cellular DNA and Epstein-Barr virus DNA in a human
      lymphoblastoid cell line.
AB  - High-molecular-weight DNA from cell line Raji (derived from Burkitt's lymphoma),
      which contains 50-60 copies of Epstein-Barr virus DNA per cell, was fractionated
      in neutral solution by several cycles of CsCl gradient centrifugation in fixed
      angle rotors. Under the fractionation conditions used, intact Epstein-Barr virus
      DNA from virus particles can be separated from the less-dense cellular DNA. In
      contrast, a large proportion of the intrinsic Epstein-Barr virus DNA component of
      Raji cells remains associated with cellular DNA, as determined by nucleic acid
      hybridization. This interaction, which is resistant to Pronase and phenol
      treatment, is not the result of aggregation. When the molecular weight of Raji
      DNA is reduced by hydrodynamic shear, the amount of virus DNA associated with
      cell DNA decreases. However, some virus DNA still remains bound to fragments of
      cellular DNA after shearing. The association is completely destroyed in alkaline
      solution. Molecular weight analysis of Raji DNA after denaturation showed that
      the alkali-induced release of Epstein-Barr virus DNA was specific and not the
      result of random single-strand breaks. These data indicate that Epstein-Barr
      virus DNA is linearly integrated into Raji cell DNA by alkali-labile bonds.

PMID- 4355372
TI  - A mutant of 3T3 cells with cyclic AMP metabolism sensitive to temperature change.
AB  - A mutant line of 3T3 (mouse fibroblast) cells with temperature-sensitive cyclic
      AMP (cAMP) metabolism was isolated by selecting for low substratum adhesiveness
      after a change in temperature. Although the mutant is identical in behavior to
      the parent cell at constant temperature, a rise or fall in temperature causes a
      fall in intracellular cAMP levels within seconds, followed by loss of adherence
      to the culture dish and retraction of cell processes. The mechanism of this fall
      in cAMP level is at least in part excretion into the medium. The decrease in
      adhesiveness and retraction of processes can be blocked by analogues of cAMP or
      agents that elevate intracellular cAMP. The properties of this mutant imply that
      cAMP is a direct regulator of cell shape and adhesiveness.

PMID- 4355373
TI  - Isolation of Escherichia coli RNA polymerase binding sites on T5 and T7 DNA:
      further evidence for sigma-dependent recognition of A-T-rich DNA sequences.
AB  - Previous isolation and analysis of E. coli RNA polymerase (EC 2.7.7.6) binding
      sites on lambda DNA had demonstrated the existence of a sigma-dependent process
      of recognition of A-T-rich DNA sequences. We have now extended this finding to T5
      and T7 DNA and have provided evidence for the double-strandedness of the isolated
      binding sites. The possible equation of these sites to the genetically defined
      promoters is discussed.

PMID- 4355374
TI  - Mechanisms of lysosomal enzyme release from human leukocytes: microtubule
      assembly and membrane fusion induced by a component of complement.
AB  - A low-molecular-weight component of complement, similar to or identical with
      human C5a, interacts with human polymorphonuclear leukocytes treated with
      cytochalasin B and provokes extracellular release of lysosomal enzymes from these
      cells. Enzyme release occurs in the absence of particles and is selective in that
      it is not accompained by release of cytoplasmic enzymes. Cell viability is not
      altered. Pharmacologic agents that regulate secretion of other inflammatory
      mediators influenced complement-dependent enzyme release: cAMP and theophylline,
      prostaglandin E(1) and colchicine inhibited, whereas cGMP enhanced release of
      enzymes. Ultra-structural histochemistry of cells exposed to this component of
      complement revealed degranulation, fusion of lysosomal with plasma membranes, and
      transient assembly of microtubules associated with the release of endogenous
      myeloperoxidase. Our findings suggest that these intracellular events are common
      to two important responses of polymorphonuclear leukocytes in inflammation and
      tissue injury: (a) release of lysosomal hydrolases and (b) chemotaxis.

PMID- 4355375
TI  - Dynamics of metabolism of normal and virus-transformed chick cells in culture.
AB  - Application of steady-state tracer technique to normal and transformed cells in
      tissue culture allows quantitation of intracellular pool sizes of many
      metabolites and determination of rate of carbon flow along diverse paths. Using a
      unique apparatus to control the environmental conditions, we show that the
      glucose carbon flow into tricarboxylic acid cycle intermediates and amino acids
      is unchanged upon transformation. The increased glycogen formation and glycolysis
      varies with the glucose concentration in the medium, correlates with the faster
      glucose transport of transformed cells, and cannot be explained by a difference
      in growth rate alone.

PMID- 4355376
TI  - Direct evidence for messenger activity of influenza virion RNA.
AB  - In a cell-free system of Escherichia coli, RNA from influenza virus particles is
      translated into a polypeptide antigenically identical with the ribonucleoprotein
      and several more proteins, some of which correspond in size to viral structural
      components.

PMID- 4355377
TI  - Epidermal growth factor: receptors in human fibroblasts and modulation of action
      by cholera toxin.
AB  - Epidermal growth factor (EGF) stimulates both DNA and RNA synthesis in contact
      inhibited human fibroblasts. Stimulation of DNA synthesis is observed at
      concentrations as low as 3 pM, is half-maximal at 70 pM, and is maximal at 300 pM
      EGF. The action of EGF is similar to that of fetal-calf serum, but is
      distinguished by the time-course of stimulation and by the ability of serum to
      stimulate further those cells maximally stimulated by EGF. Cells that synthesize
      DNA in response to physiological concentrations of EGF (10(-11) to 10(-10) M) are
      insensitive to physiological concentrations of insulin (10(-11) to 10(-10) M) and
      respond only minimally to very high concentrations of this hormone (10(-6) M).
      The biological activity of EGF is paralleled by binding of this peptide to
      fibroblasts in a specific and saturable manner; the dissociation constant is
      about 800 pM. The binding of EGF is unaffected by either insulin or cholera
      toxin. Cholera toxin inhibits the action of both EGF and serum. Suppression of
      DNA synthesis is observed at 0.02 pM toxin, and is maximal at about 2 pM. Cells
      treated with cholera toxin at these concentrations appear to be otherwise viable
      by several criteria. The stimulatory effects of EGF are also inhibited by
      theophylline and dibutyryl cyclic AMP separately or in combination. These
      observations indicate that fibroblasts possess receptors for EGF by biological
      and physicochemical criteria, and suggest that a similar if not identical peptide
      may be amongst those factors in sera which stimulate cell growth. The possibility
      is considered that EGF and cholera toxin modulate the ability of a cell to
      initiate polynucleotide synthesis by way of specific cell-surface interactions
      which in turn alter the levels of intracellular cyclic AMP.

PMID- 4355378
TI  - Linear electric field-induced shifts in electron paramagnetic resonance: a new
      method for study of the ligands of cytochrome P-450.
AB  - The linear electric field shift in paramagnetic resonance has, for the first
      time, been observed in frozen solutions. The magnitude of the shift parameters,
      measured at g(max) of the electron paramagnetic resonance absorption envelope,
      has been used to characterize lowspin ferric heme mercaptide complexes where the
      nonmercaptide ligand was varied. The magnitude of the shift provides a measure of
      the difference between the crystal field contribution of the mercaptide and
      nonmercaptide ligands. In low-spin ferric cytochrome P-450 of rat liver, the
      presence of an electric field shift indicates a deviation from inversion symmetry
      and proves that the axial ligands to the heme are not the same. From the
      magnitude of the shift and its dependence upon the angle between applied electric
      and magnetic fields, it is suggested that the non-axial ligand to the heme has a
      crystal field contribution greater than imidazole and smaller than guanidine.

PMID- 4355379
TI  - Surface antigens common to mouse cleavage embryos and primitive teratocarcinoma
      cells in culture.
AB  - Syngeneic antisera have been produced in mouse strain 129/Sv-CP males against the
      primitive cells of teratocarcinoma. These sera react specifically with the
      primitive cells and are negative on various types of differentiated teratoma
      cells derived from the same original tumor. They are negative on all other mouse
      cells tested, with the exception of male germ cells and cleavage-stage embryos.
      Thus, teratoma cells possess cell-surface antigens in common with normal cleavage
      stage embryos.

PMID- 4355380
TI  - Characterization of RNA from noninfectious virions produced by sarcoma positive
      leukemia negative transformed 3T3 cells.
AB  - RNA from noninfectious virions produced by two established clonal lines of
      sarcoma positive-leukemia negative (S+L-)-transformed 3T3 cells has been
      characterized. RNA from virions or nucleoids of S+L--(C243) cells consisted of
      three to four sizes: +/-44 S (6%), 28 S (17%), 18 S (38%), and <18 S (39%). 28S
      virion RNA contained some virus-specific information demonstrable by RNA.DNA
      hybridization with a DNA probe derived from the RNA-directed DNA polymerase
      product of murine sarcoma-leukemia virus, while parallel studies indicated that
      28S ribosomal RNA from ribosomal subunits of transformed and nontransformed 3T3
      cells did not contain virus-specific information. In contrast to the S+L-(C243)
      virions, RNA from virions or nucleoids of S+L-(D56) cells consisted of five
      sizes: 80 S (6%), 68 S (8%), 56 S (5%), 28 S (28%), and <28 S (53%). Thermal
      dissociation studies suggested that this S+L- genome is comprised of 28S RNA
      subunits. From these studies we postulate that the 28S viral RNA is most probably
      the monomeric genome of S+L- virions.

PMID- 4355381
TI  - [Lipid changes after fasting in obese patients].

PMID- 4355382
TI  - [Determination of plasma renin activity in edematous cirrhosis. Influence of
      various depletive treatments].

PMID- 4355383
TI  - [Bacteriological and epidemiological study of 427 cases of suppurating meningitis
      identified at the Centre Hospitalier Regional, Nancy, during the last 11 years.
      Comparison with a previous study].

PMID- 4355384
TI  - [Acute ethylene glycol and diethylene glycol poisoning in adults. 2 cases with
      recovery].

PMID- 4355385
TI  - [Lupic polyarthritis with gangrene of the fingers due to arterial thrombosis. A
      case with arteriographic and anatomical study].

PMID- 4355386
TI  - [Fatal post-operative meningitis due to Moraxella glucidolytica].

PMID- 4355387
TI  - Development of chloroplast substructures with apparent secretory roles in the
      young tobacco leaf.

PMID- 4355388
TI  - The fine structure of iridosphores in the skin of the Atlantic salmon (Salmo
      salar L.).

PMID- 4355389
TI  - Influence of changes in myocardial contractility on the height and slope of the
      calibrated apex cardiogram.

PMID- 4355391
TI  - The many faces of islet cell tumors.

PMID- 4355390
TI  - Angiographic diagnosis and differential diagnosis of islet-cell tumors.

PMID- 4355392
TI  - Obstructive jaundice, the radiologist, the surgeon, and the patient: Caldwell
      Lecture, 1971.

PMID- 4355393
TI  - Unilobar veno-occlusive disease of the liver. Angiographic demonstration of
      intrahepatic competition simulating hepatoma.

PMID- 4355394
TI  - An improved methodology for preparation of virus-induced double stranded RNA.

PMID- 4355395
TI  - Conformational studies on guanosine nucleotides and polynucleotides. The effect
      of the base on the glycosyl and backbone conformations.

PMID- 4355396
TI  - Parameters of stimulation of RNA synthesis and characterization by hybridization
      in a molluscan neuron.

PMID- 4355398
TI  - Postnatal development of thalamic synaptic events underlying evoked recruiting
      responses and electrocortical activation.

PMID- 4355399
TI  - Specific neural connections for the cerebellar control of vestibulo-ocular
      reflexes.

PMID- 4355397
TI  - Relations between the ventrolateral thalamic nucleus and motor cortex and their
      possible role in the central organization of motor control.

PMID- 4355400
TI  - Comparison of effects of paradoxical sleep deprivation and immobilization stress
      on 5-hydroxyindoleacetic acid in cerebrospinal fluid.

PMID- 4355401
TI  - Lyophilized combination pools of enterovirus equine antisera: preparation and
      test procedures for the identification of field strains of 42 enteroviruses.
AB  - This paper describes the preparation of 8 dried pools (designated A to H) of
      sera. Each pool is composed of 10 or 11 of 42 individual enterovirus equine sera
      and contains 500 antibody units of each serum component per 0.1 ml. Procedures
      for using the antiserum pools are given, and guidance is provided for
      interpreting the results of serum neutralization tests in identifying field
      isolates.

PMID- 4355402
TI  - Immunological problems in leprosy research. 1.
AB  - This Memorandum reviews the present status of knowledge of the immunology of
      leprosy, with particular attention to developments since the publication of a
      similar review in 1970. The different types of lepromin reaction and their
      significance in healthy contacts and in patients with tuberculoid and lepromatous
      leprosy are discussed. The immunological responsiveness of patients with leprosy
      is also considered, with special attention to in vitro methods for evaluating
      this response. Part 2 of the Memorandum will cover possible mechanisms of altered
      immune response in leprosy (including a tentative scheme to explain the possible
      genesis of the lepromatous lesion); genetic, nutritional, and hormonal factors;
      the possibility of vaccination; attempts at immunotherapy; and areas in which
      further research is needed. A detailed protocol for evaluating the effect of
      transfer factor in leprosy will be included as an annex.

PMID- 4355403
TI  - [Relationship between acupuncture analgesia and neurotransmitters in the brain].

PMID- 4355404
TI  - [Etiology and pathology of fatal flaccid paralysis of children].

PMID- 4355405
TI  - [Tracheostomy and respiratory care in epidemic encephalitis B with respiratory
      failure].

PMID- 4355406
TI  - [Interaction among prostaglandins, nerves and hormones].

PMID- 4355407
TI  - Standard reference materials: standard quartz cuvettes for high-accuracy
      spectrophotometry.

PMID- 4355408
TI  - Evaluation of a rapid latex-agglutination test for detection of alpha1
      fetoprotein.

PMID- 4355409
TI  - Plasma retinol assay by elution from silicic acid with cymene (p-lsopropyl
      toluene).

PMID- 4355410
TI  - [Separation of human plasma lipoproteins by polyacrylamide mixed gel
      electrophoresis (author's transl)].

PMID- 4355411
TI  - The effect of phospholipases on the release of enzymes from intact cells.

PMID- 4355412
TI  - Separation of lipoprotein X and beta-lipoprotein by zonal centrifugation or
      hydroxyapatite chromatography.

PMID- 4355413
TI  - Entamoeba histolytica: concurrent irreversible loss of infectivity-pathogenicity
      and encystment potential after prolonged maintenance in axenic culture in vitro.

PMID- 4355414
TI  - Microphallus pygmaeus: effect of long-acting ACTH preparation on establishment
      and retention in alimentary canal of the mouse.

PMID- 4355415
TI  - Inhibition of phosphodiesterase by dihydroergotamine and hydergine in various
      organs of the cat in vitro.

PMID- 4355416
TI  - Stimulation of transcription in HEp-2 cells by UV-inactivated poliovirus type 1.

PMID- 4355417
TI  - Effect of colchicine on long lasting synaptic modifications induced by
      hyperactivity.

PMID- 4355418
TI  - A study of the cytology and cell culture of the canine transmissible veneral
      sarcoma.

PMID- 4355419
TI  - The effect of kidney-bean leucoagglutinin on homograft rejection in mice.

PMID- 4355420
TI  - Herpes-virus and double-stranded RNA.

PMID- 4355421
TI  - Effect of triparanol (mer 29) on rat liver lysosomes: cytochemical and
      biochemical study.

PMID- 4355422
TI  - Effects of cyclic AMP and theophylline on mitogen-induced RNA synthesis in human
      peripheral blood lymphocytes.

PMID- 4355423
TI  - Fibrinolysis associated with oncogenic transformation. Requirement of plasminogen
      for correlated changes in cellular morphology, colony formation in agar, and cell
      migration.
AB  - Fetal bovine and dog serum were selectively freed of plasminogen by affinity
      chromatography. The resulting serum as well as native and reconstituted serum
      (obtained by the addition of purified plasminogen to the plasminogen-depleted
      serum) were used to examine the role of plasminogen in (a) growth of normal and
      SV-40-transformed hamster embryo fibroblasts in liquid medium, (b) growth of SV
      40-transformed hamster embryo fibroblasts in soft agar, (c) aggregation - a
      characteristic morphological change of SV-40-transformed hamster cells, and (d)
      migration of SV-40-transformed and control 3T3 cells from a monolayer into a
      "wound." The results demonstrated that exponential growth of both normal and
      transformed cells in liquid medium proceeded at the same rate in the presence or
      absence of plasminogen. In contrast, removal of plasminogen markedly depressed
      the plating efficiency of transformed cells in soft agar, eliminated their
      characteristic aggregation, and substantially reduced the extent of migration.
      The role of plasminogen and its activation in oncogenic transformation is
      discussed.

PMID- 4355424
TI  - Evidence for a macrophage-mediated effect of poliovirus on the lymphocyte
      response to phytohemagglutinin.

PMID- 4355426
TI  - The role of phosphorus restriction in the prevention of secondary
      hyperparathyroidism in chronic renal disease.

PMID- 4355425
TI  - Role of humoral and cell-mediated immunity on the recovery of chickens from
      fowlpox virus infection.

PMID- 4355428
TI  - Should a paper on the administration of chiropractic have been published in
      Medical Care? With comments on derivative questions.

PMID- 4355427
TI  - Letter: Comments on "The administration of chiropractic in the New York City
      Medicaid program".

PMID- 4355429
TI  - [Type shift in lung cancer during the last decade].

PMID- 4355430
TI  - [Corticoid and ACTH therapy of neurologic diseases].

PMID- 4355431
TI  - [Immunosuppressive therapy of myasthenias].

PMID- 4355434
TI  - Influence of cyclic AMP on early events of the immune induction.

PMID- 4355433
TI  - Effects of lysozyme on normal and transformed mammalian cells.

PMID- 4355432
TI  - [Specific therapy of neurosyphilis].

PMID- 4355436
TI  - Changes in distribution of electric charges in the surface membrane of rat
      ascites hepatocarcinoma cells induced by con A.

PMID- 4355435
TI  - New bioassay for luteinizing hormone.

PMID- 4355438
TI  - Proton magnetic resonance and the composition of proteins.

PMID- 4355440
TI  - Sleep patterns in the owl Strix aluco.

PMID- 4355439
TI  - Delta 9-tetrahydrocannabinol and the sleep-wakefulness cycle in rabbits.

PMID- 4355441
TI  - The relationship between the antidiuretic activity of rat eye plexus blood and
      passive avoidance behaviour.

PMID- 4355442
TI  - Esophagogastric substitution after total gastrectomy and distal esophagectomy for
      locally advanced gastric cancer.

PMID- 4355443
TI  - Amebiasis: newer methods of diagnosis and treatment.

PMID- 4355444
TI  - Studies on cartilage formation. XV. Enzyme histochemical investigation on Krebs
      cycle, terminal oxidation and hexose monophosphate shunt.

PMID- 4355445
TI  - Oxandrolone and human growth hormone. Comparison of growth-stimulating effects in
      short children.

PMID- 4355447
TI  - Chronic idiopathic hyperphosphatasia in an Indian child.

PMID- 4355446
TI  - Cause of acute hemorrhagic cystitis in children.

PMID- 4355448
TI  - Oral-facial dyskinesia and quadriplegia associated with poliomyelitis virus type
      3.

PMID- 4355450
TI  - Neighborhood Extension of Activity Therapy.

PMID- 4355449
TI  - Metastatic carcinoma to the pancreas. Another cause for acute pancreatitis.

PMID- 4355451
TI  - Cardiac afferent activity in depressor nerve of the chicken.

PMID- 4355452
TI  - Avian cardiac receptors: activity changes by blood pressure, carbon dioxide, and
      pH.

PMID- 4355453
TI  - Electrical discharge of single enteric neurons of guinea pig small intestine.

PMID- 4355454
TI  - Effects of angiotensin I and angiotensin II on hindlimb and coronary vascular
      resistance.

PMID- 4355455
TI  - Blast transformation of lymphocytes in amebiasis.

PMID- 4355456
TI  - Epidemiology of the acute fevers of unknown origin in South Vietnam: effect of
      laboratory support upon clinical diagnosis.

PMID- 4355457
TI  - Prostaglandins and the lung.

PMID- 4355458
TI  - Comparison of serum lipid and lipoprotein profiles of tuberculin-positive and
      tuberculin-negative monkeys (Macaca sp).

PMID- 4355459
TI  - [Endocrinological future of hypophysectomized adults, excluding diabetes
      insipidus (study of 25 cases)].

PMID- 4355460
TI  - [Metapirone test after treatment with slow-acting tetracosactide (slow-acting
      synactene)].

PMID- 4355462
TI  - Letter: Herpes simplex of penis and anus.

PMID- 4355464
TI  - Chemodectomas of the middle ear. A comparison of therapeutic modalities.

PMID- 4355463
TI  - [Antibiotic treatment of corneal ulcers due to Pseudomonas aeruginosa].

PMID- 4355461
TI  - [Plasma FSH and LH in neuro-pituitary amenorrhea. Static study and dynamic
      effects of estrogens].

PMID- 4355465
TI  - Comparative biochemical study of otosclerosis and osteogenesis imperfecta.

PMID- 4355466
TI  - Isolation and characterization of surface membranes from chorioallantoic cells
      and chick fibroblasts.

PMID- 4355467
TI  - ATPase in isolated membranes of Bacillus subtilis.

PMID- 4355468
TI  - Suramin: a potent ATPase inhibitor which acts on the inside surface of the sodium
      pump.

PMID- 4355469
TI  - Letter: Methyldopa and depression.

PMID- 4355470
TI  - A three year comparison of acute respiratory disease, shrink and weight gain in
      preconditioned and non-preconditioned Illinois beef calves sold at the same
      auction and mixed in a feedlot.
AB  - During 1969 to 1971, 78 preconditioned (PC) and 79 non-preconditioned (NPC) beef
      calves were purchased at the same auction and mixed in a feedlot. Preconditioned
      calves were weaned 30 days before the sale, used to drinking from a tank, and
      vaccinated against blackleg, malignant edema, infectious bovine rhinotracheitis
      (IBR), parainfluenza-3 (PI3) and bovine virus diarrhea (BVD) in 1970 and 1971,
      and Pasteurella hemolytica and multocida in 1971. All vaccinations were completed
      two to three weeks before the sale. PC calves were given thiabenzadole. PC calves
      had significantly less shrink after shipment and in 1971 significantly more rapid
      daily gain during the first weeks of the feeding period. In 1969 more PC calves
      were treated for acute respiratory disease than NPC calves during an outbreak of
      PI3 and BVD infection. In 1970 and 1971 fewer PC than NPC calves were treated for
      acute respiratory tract disease during outbreaks of PI3 infection. The
      differences in clinical respiratory disease were significant in 1971. Inclusion
      of two doses of P. hemolytica and P. multocida bacterin before the sale in 1971
      and use of an intranasal PI3 vaccine was considered to improve the PC program.
      Fecal egg counts for gastrointestinal nematodes were much lower in PC calves
      treated with thiabenzadole than untreated NPC calves.

PMID- 4355471
TI  - Necrotic enteritis in broiler chickens. I. A review of the literature and the
      prevalence of the disease in Ontario.
AB  - The available literature on necrotic enteritis in broiler chickens is reviewed.
      The records of three poultry diagnostic laboratories in Ontario were examined for
      the years 1969, 1970 and 1971. During this period 855 (7.7%) of 11,076
      consignments of broiler chickens examined were diagnosed as necrotic enteritis.
      The condition was most common in broilers at three weeks of age, with 66% of all
      cases occurring in chickens between two and four and one half weeks. The disease
      occurred throughout the year but it was most common during July, August,
      September and October. Necrotic enteritis often occurred more than once per year
      on a farm.

PMID- 4355472
TI  - Vesicular lesions produced in guinea pigs by a Staphylococcus aureus strain.
AB  - A bacterium isolated from vesicular lesions on foot pads of guinea pigs
      reproduced lesions similar to those seen in experimental infections of guinea
      pigs with foot-and-mouth disease virus. (FMDV). These bacterial lesions were
      produced with an inactivated FMDV suspension. Identification as Staphylococcus
      aureus was determined by growth characteristics on nutrient and blood agar, Gram
      staining, fermentation of mannitol and coagulase positive reactions. In addition,
      the organism was sensitive to concentrations of penicillin and streptomycin
      commonly used in laboratory diluents.

PMID- 4355473
TI  - Catabolism of cholesterol in hypercholesterolemia and its relationship to plasma
      triglycerides.

PMID- 4355474
TI  - Serum glycoproteins in hyperlipoproteinemic patients with and without clinical
      vascular disease.

PMID- 4355475
TI  - The excretion of adenosine 3',5'-cyclic monophosphate by children with burns.

PMID- 4355477
TI  - Induction of 3T3 cell division at the monolayer stage. Early changes in
      macromolecular processes.

PMID- 4355476
TI  - Effect of exposure to quartz dust in vivo on pentose cycle activity in guinea pig
      lung.

PMID- 4355478
TI  - A radioautographic method for the localization of steroid ligands and receptors
      by cell affinity labelling.

PMID- 4355479
TI  - Effects of N6-monobutyryl-cyclic AMP on glutamate decarboxylase activity in fetal
      rat brain cells and glial tumor cells in culture.

PMID- 4355480
TI  - Temperature sensitive cells in the study of SV40 lysis versus SV40
      transformation.

PMID- 4355481
TI  - Subcellular localization of the leucine biosynthetic enzymes in yeast.
AB  - When baker's yeast spheroplasts were lysed by mild osmotic shock, practically all
      of the isopropylmalate isomerase and the beta-isopropylmalate dehydrogenase was
      released into the 30,000 x g supernatant fraction, as was the cytosol marker
      enzyme, glucose-6-phosphate dehydrogenase. alpha-Isopropylmalate synthase,
      however, was not detected in the initial supernatant, but could be progressively
      solubilized by homogenization, appearing more slowly than citrate synthase but
      faster than cytochrome oxidase. Of the total glutamate-alpha-ketoisocaproate
      transaminase activity, approximately 20% was in the initial soluble fraction,
      whereas solubilization of the remainder again required homogenization of the
      spheroplast lysate. Results from sucrose density gradient centrifugation of a
      cell-free particulate fraction and comparison with marker enzymes suggested that
      alpha-isopropylmalate synthase was located in the mitochondria. It thus appears
      that, in yeast, the first specific enzyme in the leucine biosynthetic pathway
      (alpha-isopropylmalate synthase) is particulate, whereas the next two enzymes in
      the pathway (isopropylmalate isomerase and beta-isopropylmalate dehydrogenase)
      are "soluble," with glutamate-alpha-ketoisocaproate transaminase activity being
      located in both the cytosol and particulate cell fractions.

PMID- 4355482
TI  - Isolation and characterization of two protease-producing mutants from
      Staphylococcus aureus.
AB  - Two mutants with increased protease production were isolated after
      nitrosoguanidine treatment of Staphylococcus aureus 8325N. The wild type produces
      low amounts of extracellular proteolytic activity. The enzyme was inducible and
      could only be detected if casein or preferably skim milk powder was used as
      inducer. The optimal pH, salt concentration, and media for enzyme production were
      determined. The mutants differed from the wild type in several phenotypic
      characters. The pattern of extracellular deoxyribonuclease and alkaline
      phosphatase differed between the mutants and the wild type. Several carbohydrates
      such as lactose, galactose, and mannitol were not utilized by the mutants,
      probably owing to a block in the uptake. Glucose could, however, be utilized by
      the mutants. Reversion frequency to wild type with regard to carbohydrate
      utilization was spontaneously high, and all revertants regained the parental
      pattern irrespective of the carbohydrate used for selection. The results suggest
      that a single locus may control the excretion of extracellular enzymes and
      carbohydrate uptake in S. aureus.

PMID- 4355483
TI  - Purification and properties of Lactobacillus plantarum inducible malic enzyme.
AB  - Inducible malic enzyme (l-malate:NAD oxidoreductase [decarboxylating], EC
      1.1.1.39) was isolated from Lactobacillus plantarum and purified about 100-fold
      with 27% yield of the original activity. Kinetic studies with the purified malic
      enzyme yielded the following results: pH optimum, 7.6 to 8.0; K(m) for l-malate,
      0.38 mM; K(m) for NAD, 0.072 mM; and K(m) for MnCl(2), 0.048 mM. It was shown
      that this enzyme was inhibited by high concentrations of substrate and
      nicotinamide adenine dinucleotide (NAD), indicating it may be regulated by
      substrate or NAD. Molecular weight of 130,000 +/- 10,000 was determined by
      Sephadex gel filtration and sodium dodecyl sulfate-polyacrylamide gel
      electrophoresis. The isoelectric point, determined by isoelectrofocusing, was 4.3
      at 7 C. Isoelectrofocusing also resolved three active peaks which focused at pH
      4.19, 4.31, and 4.40.

PMID- 4355484
TI  - Pyrimidine metabolism in Acinetobacter calcoaceticus.
AB  - The metabolism of thymine, thymidine, uracil, and uridine has been investigated
      in five different strains of Acinetobacter calcoaceticus. Attempts to isolate
      thymine and thymidine auxotrophic mutants were not successful. Consistent with
      this finding was the observation that uptake of radioactive thymine or thymidine
      could not be demonstrated. Search for enzymes capable of transforming thymine via
      thymidine to thymidine-5'-monophosphate in crude extracts was performed, and the
      following enzymes were absent judging from enzyme assays: thymidine phosphorylase
      (EC 2.4.2.4), trans-N-deoxyribosylase (EC 2.4.2.6), and thymidine kinase (EC
      2.7.1.21). The enzymes responsible for the phosphorylation of thymidine-5'
      monophosphate to thymidine-5'-triphosphate were present in crude extracts.
      Radioactive uracil was readily incorporated into both ribonucleic acid and
      deoxyribonucleic acid, the ratio being 6:1, and radioactivity was found only in
      pyrimidine bases. No uptake of uridine could be demonstrated. Uridine-5'
      monophosphate pyrophosphorylase (EC 2.4.2.9) activity was detected in crude
      extracts, suggesting that uracil is converted directly to uridine-5'
      monophosphate which is then phosphorylated to uridine-5'-triphosphate or
      transformed to other ribo- and deoxypyrimidine nucleotides.

PMID- 4355485
TI  - Sensitization by ethylenediaminetetraacetate of Clostridium perfringens type A
      spores to germination by lysozyme.
AB  - Clostridium perfringens spores (three strains) were normally resistant to
      germination by lysozyme. In the absence of disulfide bond-breaking reagents,
      tetrasodium ethylenediaminetetraacetate rapidly sensitized the spores to
      lysozyme.

PMID- 4355486
TI  - Isolation and characterization of a mutant of Salmonella typhimurium deficient in
      a major deoxyribonucleic acid polymerase activity.
AB  - A mutant of Salmonella typhimurium strain LT2 that is deficient in a major
      deoxyribonucleic acid (DNA) polymerase activity has been isolated and
      characterized. This mutant resembles the pol mutants of E. coli in that it has
      low DNA polymerase activity and it is sensitive to methyl methane sulfonate as
      well as ultraviolet irradiation. Revertants selected for methyl methane sulfonate
      resistance are no longer sensitive to ultraviolet irradiation and contain normal
      DNA polymerase levels. No direct role in replication can be ascribed to this
      polymerase activity since cells grow well in its absence. In addition, the LT2
      plasmid has been shown to exist in the mutant strain.

PMID- 4355487
TI  - Evidence for proteolytic degradation of histidinol phosphate phosphatase
      specified by nonsense mutants of the hisB gene of Salmonella typhimurium.
AB  - The gene products from hisB nonsense mutants having histidinol phosphate
      phosphatase activity were isolated from Salmonella typhimurium. The enzyme from
      strain TR691 (hisB278 hisT1529 aroD5) was isolated in the presence of
      diisopropylfluorophosphate. Three electrophoretically separable forms were
      demonstrated, and all were shown to have a mol wt of approximately 38,000 and to
      consist of a single polypeptide chain. Previously, two forms of the phosphatase
      enzyme from this strain were isolated without diisopropylfluorophosphate and
      shown to have a different subunit composition. Strain TA387 (hisB2133 his 01242)
      was shown to have two electrophoretically separable phosphatases with a mol wt of
      about 52,000 and consisted of 17,000- to 19,000-mol wt polypeptide chains as
      evidenced by polyacrylamide gel electrophoresis in sodium dodecyl sulfate. The
      results could be explained by proteolytic cleavage of the primary gene product
      which can partially be prevented by the protease inhibitor. Strain TA387
      phosphatase lost all activity in 8 M urea but could be renatured by dialysis. Gel
      filtration showed that it also regained its original molecular weight. The values
      of K(m) of histidinol phosphate and the competition inhibition constant for
      histidinol were determined. The addition of MnCl(2) to the assay was shown to
      shift the optimal pH value to a lower pH value.

PMID- 4355488
TI  - Trehalose metabolism in germinating spores of Streptomyces hygroscopicus.
AB  - Evidence is presented which indicates that utilization of trehalose is an early
      event in spore germination in Streptomyces hygroscopicus. Early in spore
      germination and before any increase in cell mass, the activity of trehalase
      increased more than 15-fold, while the intracellular content of trehalose fell to
      very low levels. On the other hand, increased activity of the trehalose phosphate
      synthetase or disappearance of glycogen did not occur until later in germination,
      during which time cell mass was also increasing.

PMID- 4355489
TI  - Altered mitochondrial respiration in a chromosomal mutant of Neurospora crassa.
AB  - A mutant of Neurospora crassa (cni-1) has been isolated that has two pathways of
      mitochondrial respiration. One pathway is sensitive to cyanide and antimycin A,
      the other is sensitive only to salicyl hydroxamic acid. Respiration can proceed
      through either pathway and both pathways together in this mutant account for
      greater than 90% of all mitochondrial respiration. The cni-1 mutation segregates
      as a nuclear gene in crosses to other strains of Neurospora. Absorption spectra
      of isolated mitochondria from cni-1 show typical b- and c-type cytochromes but
      the absorption peaks corresponding to cytochrome aa(3) are not detectable.
      Extraction of soluble cytochrome c-546 from these mitochondria followed by
      reduction with ascorbate reveals a new absorption peak at 426 nm that is not
      present in wild-type mitochondria. This peak may be due to an altered cytochrome
      oxidase with abnormal spectral properties. Mitochondria from cni-1 have elevated
      levels of succinate-cytochrome c reductase but reduced levels of nicotinamide
      adenine dinucleotide reduced form cytochrome c reductase and of cyanide- and
      azide-sensitive cytochrome c oxidase. These studies suggest that the cni-1
      mutation results in the abnormal assembly of cytochrome c oxidase so that the
      typical cytochrome aa(3) spectrum is lost and the enzyme activity is reduced. As
      a consequence of this alteration, a cyanide-insensitive respiratory pathway is
      elaborated by these mitochondria which may serve to stimulate adenosine 5'
      triphosphate production via substrate level phosphorylation by glycolysis and the
      Krebs cycle.

PMID- 4355490
TI  - Purification and properties of cytoplasmic and mitochondrial malate
      dehydrogenases of Physarum polycephalum.
AB  - Two isoenzymes of malate dehydrogenase (MDH) were demonstrated in plasmodia of
      Physarum polycephalum by polyacrylamide-gel electrophoresis. The more "cathodal"
      form was uniquely associated with mitochondria (M-MDH) and the other form was
      found in the soluble cytoplasm (S-MDH). The isoenzymes were separated by acetone
      fractionation of soluble plasmodial homogenates acidified to pH 5.0. The M-MDH
      was purified 201-fold by cetylpyridinium chloride treatment, fractionation with
      ammonium sulfate, gradient elution from sulfoethyl cellulose at pH 6.0, and
      Sephadex G-100 chromatography. The S-MDH was purified 155-fold by ammonium
      sulfate fractionation, diethylaminoethyl cellulose chromatography, gradient
      elution from sulfoethyl cellulose at pH 5.5, and Sephadex G-100 chromatography.
      The optimal cis-oxalacetate concentrations were 0.35 mM for M-MDH and 0.25 mM for
      S-MDH, and the optimal pH for both isoenzymes was 7.6 for oxalacetate reduction.
      The optimal l-malate concentrations were 5 mM for S-MDH and 6 mM for M-MDH, and
      both isoenzymes exhibited an optimal pH of 10.0 for L-malate oxidation. The
      Michaelis constants of S-MDH and M-MDH served to discriminate between the
      isoenzymes. The S-MDH was more heat-stable than the M-MDH. High concentrations of
      oxalacetate and malate inhibited S-MDH more than M-MDH. The isoenzymes were
      further distinguished by their utilization of analogues of nicotinamide adenine
      dinucleotide. Many properties of the Physarum isoenzymes were similar to those of
      more complex organisms, especially vertebrates.

PMID- 4355491
TI  - Cyclic 3',5'-adenosine monophosphate phosphodiesterase of Escherichia coli.
AB  - The cyclic 3',5'-adenosine monophosphate (c-AMP) phosphodiesterase from
      Escherichia coli has been partially purified. The enzyme has an apparent
      molecular weight of 30,000, a Michaelis constant of 0.5 mM c-AMP, and a pH
      optimum of 7. The partially purified enzyme requires for activity the presence of
      a reducing compound and of either iron or a protein which seemingly acts as iron
      carrier.

PMID- 4355493
TI  - Ultrastructural aspects of a mutant of Schizophyllum commune with continuous
      nuclear migration.
AB  - Study of a mutant of the basidomycete Schizophyllum commune with continuous
      migration of nuclei revealed that the mutant is characterized by vacuolization,
      bundles of fibrillar-like material, and microtubules. The bundles of fibrillar
      like material and microtubules extend through degraded septa to adjacent cells
      and are found in proximity to nuclei.

PMID- 4355492
TI  - Mutants of Escherichia coli K-12 "cryptic," or deficient in 5'-nucleotidase
      (uridine diphosphate-sugar hydrolase) and 3'-nucleotidase (cyclic
      phosphodiesterase) activity.
AB  - Mutants of Escherichia coli have been selected for the absence of 5'-nucleotidase
      (uridine diphosphate-sugar hydrolase) and 3'-nucleotidase (2',3'-cyclic
      phophodiesterase). Mutants selected for the absence of 5'-nucleotidase are of two
      kinds: those that lack detectable activity for the enzyme (Ush(-)), and those
      that possess activity when cell extracts are assayed, but not when intact cells
      are assayed (cryptic; Crp(-)). The latter class is probably identical to a type
      of mutant previously reported by Ward and Glaser. When mutants are selected for
      the absence of 3'-nucleotidase, Crp(-)mutants are also obtained. Thus far,
      however, mutants totally lacking this enzyme have not been found. The location on
      the genetic map of one ush mutation is at position 11 min and that of one crp
      mutation at approximately 67 min. In the crp mutant, 5'-nucleotidase and 3'
      nucleotidase remain located in the periplasm. This mutant is also cryptic for
      alkaline phosphatase but not for acid hexose phosphatase. Treatment of cells with
      ethylenediamine-tetraacetate substantially alleviated crypticity. These data are
      discussed in terms of the organization of periplasmic enzymes and of the outer
      membrane as a permeability barrier.

PMID- 4355494
TI  - Ascorbate oxidase. Spectral characteristics of the enzyme.

PMID- 4355495
TI  - Expression of genes for metabolism of cyclic adenosine 3':5'-monophosphate in
      somatic cells. I. Responses to catecholamines in parental and hybrid cells.

PMID- 4355496
TI  - Expression of genes for metabolism of cyclic adenosine 3':5'-monophosphate in
      somatic cells. II. Effects of prostaglandin E1 and theophylline on parental and
      hybrid cells.

PMID- 4355497
TI  - Cu (II)-carbon bonding in cyanide complexes of copper enzymes. 13C splitting of
      the Cu(II) electron spin resonance.

PMID- 4355498
TI  - High spin and low spin forms of Co(II) carbonic anhydrase. Temperature-dependent
      changes in spin state and coordination geometry.

PMID- 4355499
TI  - Studies on T3-induced ribonucleic acid polymerase. 3. Purification and
      characterization of the T3-induced ribonucleic acid polymerase from bacteriophage
      T3-infected Escherichia coli cells.

PMID- 4355501
TI  - Capacity for steroidogenesis of adrenals in hypophysectomized and
      adrenocorticotropic hormone-treated hypophysectomized rats. Implication of a
      ribonucleic acid for hormone-induced steroidogenesis.

PMID- 4355500
TI  - The nucleotide sequence of a serine transfer ribonucleic acid from Escherichia
      coli.

PMID- 4355502
TI  - Comparison of the effects of adrenocorticotropic hormone on the steroidogenic
      activity and ultrastructure of adrenal cortex.

PMID- 4355503
TI  - 1,24,25-Trihydroxyvitamin D3. A metabolite of vitamin D3 effective on intestine.

PMID- 4355506
TI  - The variety of intraspecific misacylations carried out by isoleucyl transfer
      ribonucleic acid synthetase of Escherichia coli.

PMID- 4355504
TI  - Chemical synthesis of delta 7,24-(3alpha-3H)cholestadien-3beta-ol and its
      conversion to cholesterol in the rat.

PMID- 4355505
TI  - Positional specificity of purified milk lipoprotein lipase.

PMID- 4355508
TI  - Control of steroidogenesis in pre-ovulatory cells. Luteinizing hormone
      stimulation of (14C)-acetate incorporation into sterols.

PMID- 4355507
TI  - A role for the microtubular system in the release of very low density
      lipoproteins by perfused mouse livers.

PMID- 4355509
TI  - Synthesis and antiviral activity of homologs of noformycin.

PMID- 4355510
TI  - Angiotensin II. Synthesis and biological activity of 6-(1-methylhistidine) and 6
      (3-methylhistidine) analogs.

PMID- 4355511
TI  - Effect of dietary protein and magnesium on selected ATP phosphotransferases and
      neuromuscular behavior in young rats.

PMID- 4355512
TI  - Occult carcinoma of second breast following mastectomy.

PMID- 4355514
TI  - Phospholipids and calcium uptake in experimental tumors.

PMID- 4355513
TI  - [8 cases of benign bronchopulmonary tumors].

PMID- 4355515
TI  - Effects of dibutyryl cyclic AMP and related compounds on newt limb regeneration
      blastemas in vitro. I. 3H-thymidine incorporation.

PMID- 4355516
TI  - Effects of dibutyryl cyclic AMP and related compounds on newt limb regeneration
      blastemas in vitro. II. 14C-leucine incorporation.

PMID- 4355517
TI  - Somatosympathetic reflexes: afferent fibers, central pathways, discharge
      characteristics.

PMID- 4355518
TI  - Neural processes in thermoregulation.

PMID- 4355519
TI  - [Role of adenosine 3',5'-monophosphate in the regulation of cell growth in vitro
      (author's transl)].

PMID- 4355520
TI  - [Role of disulfide bond disruption in ultraviolet inactivation of enzymes and
      hormones (author's transl)].

PMID- 4355521
TI  - [Treatment of myasthenia with adrencorticotrophins (ACTH and Synacthen). Apropos
      of 100 treatments in 25 patients].

PMID- 4355522
TI  - Amoebic infection of the female genital tract. A report of three cases.

PMID- 4355523
TI  - Phosphorylation of muscle membranes: identification of a membrane-bound protein
      kinase.
AB  - A membrane-bound protein kinase occurs in membranes derived from rat skeletal
      muscle and appears limited to a surface membrane fraction. The enzyme is
      magnesium dependent, is only minimally stimulated by cyclic nucleotides, and
      phosphorylates serine and to a lesser extent threonine residues of three membrane
      proteins with molecular weights of less than 30,000.

PMID- 4355524
TI  - Oscillation of cyclic adenosine monophosphate concentration during the myocardial
      contraction cycle.
AB  - The concentration of adenosine 3',5'-monophosphate (cyclic AMP) rises and falls
      during each myocardial contraction cycle. Peak concentrations of cyclic AMP
      precede peak development of systolic tension. Epinephrine alters the normal
      oscillation in myocardial cyclic AMP and increases both diastolic and systolic
      concentrations of the cyclic nucleotide. These transient changes in myocardial
      cyclic AMP indicate a potential role for cyclic AMP as a beat-to-beat regulator
      of myocardial contractility.

PMID- 4355525
TI  - Pancreatitis and hyperlipoproteinemia.

PMID- 4355526
TI  - Differences in the response of normal and transformed BHK21 cells to dual virus
      infection. Conditions affecting synergism between vesicular stomatitis virus and
      newcastle disease virus.

PMID- 4355527
TI  - Presence of antigen common to avian tumor viral envelope antigen in normal chick
      embryo cells.

PMID- 4355528
TI  - Evidence for helper independent murine sarcoma virus. I. Segregation of
      replication-defective and transformation-defective viruses.

PMID- 4355530
TI  - Specificity of TMV RNA encapsidation: in vitro coating of heterologous RNA by TMV
      protein.

PMID- 4355529
TI  - Protein metabolism in SV40-infected cells.

PMID- 4355532
TI  - Diffusion coefficients and hydrodynamic radii of three spherical RNA viruses by
      laser light scattering.

PMID- 4355531
TI  - Effects of omentumectomy on production of endotoxin-type interferon in mice.

PMID- 4355533
TI  - Differential expression of transformation in rat and chicken cells infected with
      an avian sarcoma virus ts mutant.

PMID- 4355534
TI  - Effects of dibutyryl-cAMP on adenovirus replication in different cell lines.

PMID- 4355535
TI  - Synthesis of complementary RNA by poliovirus polymerase in vitro.

PMID- 4355536
TI  - Size of gene sequences shared by polioviruses types 1, 2, and 3.

PMID- 4355537
TI  - Analysis of the inhibition of the ACTH release by hypothalamic implants of
      atropine.

PMID- 4355538
TI  - Stimulation of ornithine decarboxylase and nuclear RNA polymerase activity in rat
      liver by glucagon and dibutyryl cyclic amp.

PMID- 4355539
TI  - Effect of D2O and nicotinamide adenine dinucleotide on the sedimentation
      properties and structure of glyceraldehyde phosphate dehydrogenase.

PMID- 4355541
TI  - Nuclear magnetic resonance studies of the interaction of valinomycin with
      unsonicated lecithin bilayers.

PMID- 4355540
TI  - Isolation and characterization of the cyanogen bromide fragments from the high
      density apolipoprotein glutamine I.

PMID- 4355542
TI  - Competitive inhibitors of renin.

PMID- 4355543
TI  - Functional arginyl residues in carboxypeptidase A. Modification with butanedione.

PMID- 4355544
TI  - Interaction of actin with analogs of adenosine triphosphate.

PMID- 4355545
TI  - Correlation between a specific isoaccepting lysyl transfer ribonucleic acid and
      cell division in mammalian tissues.

PMID- 4355546
TI  - Properties of tRNALys4 from various tissues.

PMID- 4355547
TI  - Nature and possible functions of association between glutamate dehydrogenase and
      cardiolipin.

PMID- 4355548
TI  - Uridylic acid synthesis in Ehrlich ascites carcinoma. Properties, subcellular
      distribution, and nature of enzyme complexes of the six biosynthetic enzymes.

PMID- 4355549
TI  - Amino acid sequence of a cytochrome c from the common Pacific lamprey,
      Entosphenus tridentatus.

PMID- 4355550
TI  - Some properties of cross-linked polymers of glutamic dehydrogenase.

PMID- 4355551
TI  - Synthesis and characterization of photoaffinity labels for adenosine 3':5'-cyclic
      monophosphate and adenosine 5'-monophosphate.

PMID- 4355552
TI  - On the photoaffinity labeling of rabbit muscle phosphofructokinase with O2'
      (ethyl-2-diazomalonyl)adenosine 3':5'-cyclic monophosphate.

PMID- 4355553
TI  - Fluorescence properties of octopine dehydrogenase.

PMID- 4355555
TI  - Characterization of modified myosin at low ionic strength. Enzymatic and spin
      label studies.

PMID- 4355554
TI  - Independent protein synthesis in isolated rat tumor nucleoli. Aminoacylation of
      endogenous transfer ribonucleic acid.

PMID- 4355557
TI  - Immune response to the collagen-like synthetic ordered polypeptide (L-Pro-Gly-L
      Pro)n.

PMID- 4355556
TI  - Nuclear magnetic resonance and spin-label studies of hemoglobin Kempsey.

PMID- 4355558
TI  - Heterogeneity of the outer membrane of mitochondria.

PMID- 4355559
TI  - Preparation and active-site specific properties of sturgeon muscle glyceraldehyde
      3-phoshate dehydrogenase.

PMID- 4355560
TI  - Microcalorimetric study of isolated blood platelets in the presence of thrombin
      and other aggregating agents.

PMID- 4355561
TI  - Human chorionic gonadotropin-mediated glycogenolysis in human placental villi: a
      role of prostaglandins.

PMID- 4355562
TI  - Factors affecting the adrenocorticotropic hormone stimulation of rabbit adrenal
      17alpha-hydroxylase activity.

PMID- 4355563
TI  - Prolonged retention of high specific activity by 125I-labeled angiotensin II--a
      consequence of 'decay catastrophe'.

PMID- 4355564
TI  - Photolumazines, new naturally occurring inhibitors of riboflavin synthetase.

PMID- 4355565
TI  - Ionic control of renal gluconeogenesis. II. The effects of Ca2+ and H+ upon the
      response to parathyroid hormone and cyclic AMP.

PMID- 4355566
TI  - Ionic control of renal gluconeogenesis. IV. Effect of extracellular phosphate
      concentration.

PMID- 4355567
TI  - Endogenous ACTH induced remission in myasthenia gravis.

PMID- 4355568
TI  - Evidence for neuropathy in myotonic muscular dystrophy.

PMID- 4355569
TI  - [Treatment of choriocarcinoma and chorioadenoma destruens with high dosage
      chemotherapy].

PMID- 4355571
TI  - [Antilipolytic role of tetracycline. Inhibition of adenylate cyclase in vitro].

PMID- 4355570
TI  - The effect of diazoxide in children with islet cell adenomas.

PMID- 4355572
TI  - The effect of stress induced by ether anaesthesia on cholesterol content and
      cholesteryl-esterase activity in rat-adrenal cortex.

PMID- 4355573
TI  - Baldness: a disease?

PMID- 4355574
TI  - Epidemiological factors in lung cancer among women in El Pasco County, Texas 1944
      1969.

PMID- 4355575
TI  - Women's programs at DHEW.

PMID- 4355576
TI  - Women doctors educating others. 50th anniversary of the American Medical Women's
      Association Scholarship Loan Fund.

PMID- 4355577
TI  - Action of Vibrio cholerae neuraminidase (sialidase) upon the surface of intact
      cells and their isolated sialolipid components.

PMID- 4355578
TI  - Methionyl residue critical for activity and regulation of bovine liver glutamate
      dehydrogenase.

PMID- 4355579
TI  - Extensive incorporation of (2-14C) mevalonic acid into cholesterol precursors by
      human platelets in vitro.

PMID- 4355580
TI  - Effect of exercise on the turnover of cytochrome c in skeletal muscle.

PMID- 4355581
TI  - Effects of insulin on the levels of adenosine 3':5'-monophosphate and lipolysis
      in isolated rat epididymal fat cells.

PMID- 4355582
TI  - Iron and free radical in ribonucleotide reductase. Exchange of iron and Mossbauer
      spectroscopy of the protein B2 subunit of the Escherichia coli enzyme.

PMID- 4355583
TI  - Liver cytosol corticosteroid binder II, a hormone receptor.

PMID- 4355584
TI  - Deoxyribonucleic acid ligase. Isolation and physical characterization of the
      homogeneous enzyme from Escherichia coli.

PMID- 4355585
TI  - Deoxyribonucleic acid ligase. A steady state kinetic analysis of the reaction
      catalyzed by the enzyme from Escherichia coli.

PMID- 4355586
TI  - Metalloflavoenzyme models. The crystal structure of bis (10-methylisoalloxazine)
      copper (II) perchlorate tetrahydrate.

PMID- 4355587
TI  - Alkylation of an essential histidine residue in porcine spleen deoxyribonuclease.

PMID- 4355588
TI  - Receptor for thyrotropin-releasing hormone in plasma membranes of bovine anterior
      pituitary gland. Role of lipids.

PMID- 4355589
TI  - Physical properties of a purified cyclic adenosine 3':5'-monophosphate-dependent
      protein kinase from bovine heart muscle.

PMID- 4355590
TI  - Preliminary report on the electron paramagnetic resonance spectra of single
      crystals of bovine erythrocyte superoxide dismutase.

PMID- 4355591
TI  - Determination of aza-heterocyclic compounds in atmospheric dust by a combination
      of thin-layer and gas chromatography.

PMID- 4355592
TI  - Role of adrenal hormones in incubation behavior of male ring doves (Streptopelia
      risoria).

PMID- 4355593
TI  - Synthesis and antiviral activity of 1,2,4-triazole-3-thiocarboxamide and 1,2,4
      triazole-3-carboxamidine ribonucleosides.

PMID- 4355594
TI  - Synthesis of 5'-phosphates of the naturally occurring 6-ureidopurine
      ribonucleosides and their analogs.

PMID- 4355595
TI  - Different cyclic AMP requirements for induction of the arabinose and lactose
      operons of Escherichia coli.

PMID- 4355597
TI  - Recurrence of the cytochrome fold in a nitrate-respiring bacterium.

PMID- 4355596
TI  - RNA-directed DNA polymerase of Rous sarcoma virus: initiation of synthesis with
      70 S viral RNA as template.

PMID- 4355598
TI  - Mutagenic specificity: reversion of iso-1-cytochrome c mutants of yeast.

PMID- 4355599
TI  - Public health implications of Marek's disease virus and herpesvirus of turkeyes.
      Studies on human and subhuman primates.

PMID- 4355600
TI  - Preparation of membrane fractions with enhanced tumor-transplantation-antigen
      activity from tumor cells infected with influenza virus.

PMID- 4355601
TI  - Lymphomas in BALB-c mice inoculated with supernatants from chemically induced
      sarcomas.

PMID- 4355602
TI  - Differential response of rat tooth germs to a murine sarcoma virus in cell
      culture and syngeneic transplants.

PMID- 4355603
TI  - Prevalence of type-C particles in visceral tissues of embryonic and newborn mice.

PMID- 4355604
TI  - XC cell cytopathogenicity as an assay for murine myeloma C-type virus.

PMID- 4355605
TI  - A spontaneous lower motor neuron disease apparently caused by indigenous type-C
      RNA virus in wild mice.

PMID- 4355606
TI  - Rous sarcoma virus-induced tumors in marmosets: characteristics of tumor cells
      and host cell-virus interrelationships.

PMID- 4355607
TI  - Effect of streptozotocin in the Chinese hamster (Cricetulus griseus).

PMID- 4355608
TI  - Brief communication: circulating antigen-antibody complex associated with Epstein
      Barr virus in recurrent Burkitt's lymphoma.

PMID- 4355609
TI  - Brief communication: In vitro host range and serologic studies on RD-114 virus.

PMID- 4355610
TI  - Stereochemistry in the solvolytic ring contraction of 2,2,4a alpha-trimethyl-1
      decalyl methanesulfonate. A model reaction pertaining to triterpene biogenesis.

PMID- 4355611
TI  - Implications of the incest taboo for nursing practice.

PMID- 4355612
TI  - Managing member silence in family therapy.

PMID- 4355614
TI  - Philosophy and structure of a day treatment center.

PMID- 4355615
TI  - The role of science in the World Health Organization.

PMID- 4355613
TI  - The CVA patient as an indication of general patient need.

PMID- 4355616
TI  - Speaking out on: professional rejection of the longer-term patient??

PMID- 4355617
TI  - Food for the elderly.

PMID- 4355618
TI  - Problems of a nurse group on an inpatient psychiatric unit.

PMID- 4355619
TI  - Organization of emergency services: the crisis nurse in the community mental
      health center.

PMID- 4355620
TI  - Skin test in bronchogenic carcinoma. I. Correlation of the immunological status
      and the extent of the disease.

PMID- 4355621
TI  - Cross-classification and survival characteristics of 5,000 cases of cancer of the
      pancreas.

PMID- 4355622
TI  - Pseudomonas meningitis complicating radical resection for radiorecurrent cancer
      of the paranasal sinuses: report of two patients successfully treated with
      intrathecal polymyxin.

PMID- 4355623
TI  - Water pollution: microbiology of water.

PMID- 4355624
TI  - Microbiology--detection and occurrence of viruses.

PMID- 4355625
TI  - Radiotherapy of adenoid cystic carcinoma of the head and neck.

PMID- 4355626
TI  - [Urine kininase activity in renal diseases].

PMID- 4355628
TI  - [Effective time of eye activity during REM sleep stages].

PMID- 4355627
TI  - [Organization of nocturnal sleep during ontogenesis in the chimpanzee less than
      42 months old].

PMID- 4355629
TI  - Management of alleged sexual assault.

PMID- 4355630
TI  - A comparative follow-up of functional psychoses in women.

PMID- 4355631
TI  - Rapid new soft x-ray technique for determination of quartz in coal mine dusts.

PMID- 4355632
TI  - Epidemiology of respiratory syncytial virus infection in Washington, D.C. 3.
      Composite analysis of eleven consecutive yearly epidemics.

PMID- 4355634
TI  - The road to Shangri-La is paved with vitamins.

PMID- 4355633
TI  - Adrenocortical function in acromegaly.

PMID- 4355636
TI  - Halothane stereoisomers: lack of stereospecificity in two model systems.

PMID- 4355635
TI  - Antagonism of d-tubocurarine- and pancuronium-induced neuromuscular blockades by
      pyridostigmine in man.

PMID- 4355637
TI  - Letter: Standardized technique for transmission studies.

PMID- 4355638
TI  - Postoperative endophthalmitis following cataract surgery. Effects on
      subconjunctival antibiotics and other factrs.

PMID- 4355639
TI  - Chronic ulcerative keratitis caused by herpes simplex virus.

PMID- 4355640
TI  - Endocrine spotlights on brain and behaviour.

PMID- 4355641
TI  - [Cylindroma of the jaw and face. Current aspects of therapy based on long-term
      observations].

PMID- 4355642
TI  - [Cytomegalovirus infection and the Guillain-Barre syndrome (author's transl)].

PMID- 4355643
TI  - An insoluble fibrogenic factor in macrophages from guinea pigs exposed to silica.

PMID- 4355644
TI  - Noradrenergic pathways and sleep-waking states in cats.

PMID- 4355645
TI  - Polarization changes in the terminals of identified primary afferent fibers at
      the gracile nucleus.

PMID- 4355646
TI  - Studies on single neurons in dorsal hippocampal formation and septum in
      unrestrained rats. I. Behavioral correlates and firing repertoires.

PMID- 4355647
TI  - [Changes in the level of the protein content of the motor neurons of the spinal
      cord under the influence of synaptic excitation and inhibition].

PMID- 4355648
TI  - [Evaluation of the quantum content of excitatory postsynaptic potentials in
      neuromuscular synapses of a complex type].

PMID- 4355649
TI  - [Effect of sympatholytin on metabolism in resting and working muscles as related
      to the degree of their adaptation to increased activity].

PMID- 4355650
TI  - [Regulation of calcium and strontium absorption in the small intestine of
      chickens].

PMID- 4355652
TI  - [Neurogenic mediastinal tumors with endocrine activity].

PMID- 4355651
TI  - [Mechanism of the polyuric phase of the action of neurohypophyseal hormones].

PMID- 4355653
TI  - [Islet cell tumor of the pancreas in a 7-year-old girl].

PMID- 4355654
TI  - Molybdenum(IV) in aqueous solutions.

PMID- 4355656
TI  - Is anatomy destiny? Panel: the changing role of women psychiatrists.

PMID- 4355655
TI  - Dysfunction patterns analogous to frontal lobe system and caudate nucleus
      syndromes in some groups of minimal brain dysfunction.

PMID- 4355657
TI  - New Jersey women physicians--their opinions on today's world.

PMID- 4355658
TI  - Hypertension in terminal renal failure. Observations pre and post bilateral
      nephrectomy.

PMID- 4355659
TI  - Renovascular hypertension: incidence, diagnosis, mechanism and treatment.

PMID- 4355660
TI  - Stannous pyrophosphate labeled with technetium-99m for skeletal scintigraphy.

PMID- 4355661
TI  - Antagonism of vasoconstrictor responses by exercise in the gracilis muscle of the
      dog.

PMID- 4355662
TI  - A new technique for treating esophageal varices.

PMID- 4355663
TI  - [Epstein-Barr-virus antibodies in sarcoidosis (author's transl)].

PMID- 4355665
TI  - Nephroblastoma: index cancer of childhood.

PMID- 4355664
TI  - [Diagnosis and treatment of 153 mixed tumors of the parotid gland].

PMID- 4355666
TI  - Low back pain. Differential diagnosis determines treatment: hospitalization
      enables more efficient treatment.

PMID- 4355668
TI  - Vitamin D-like action of Solanum malacoxylon on calcium transport by rat
      intestine.

PMID- 4355667
TI  - Morphine tolerance and supersensitivity to 5-hydroxytryptamine in the myenteric
      plexus of the guinea-pig.

PMID- 4355669
TI  - Effect of cyclic AMP on growth and morphological differentiation of an
      established myogenic cell line.

PMID- 4355670
TI  - Agglutination with con A dependent on cell cycle.

PMID- 4355671
TI  - Depletion of serum growth factors by 3T3 mouse fibroblasts and viral
      transformants.

PMID- 4355672
TI  - Adrenaline-like effects of intracellular iontophoresis of cyclic AMP in cardiac
      Purkinje fibres.

PMID- 4355673
TI  - NMR evidence against gamma turn and beta turn models of angiotensin II in aqueous
      solution.

PMID- 4355674
TI  - Electronic sector scanning in the diagnosis of cerebrovascular disease and space
      occupying processes.

PMID- 4355675
TI  - Serum immunoglobulin and complement (C3) levels: a study in adults with
      idiopathic, chronic polyneuropathies and motor neuron diseases.

PMID- 4355676
TI  - The effect of cold on nerve conduction of human slow and fast nerve fibers.

PMID- 4355677
TI  - Studies on the synaptic facilitatory action of nikethamide.

PMID- 4355678
TI  - Electroencephalographic study of the effects of tetrahydrocannabinols on sleep in
      the rat.

PMID- 4355679
TI  - Functional organelles in prokaryotes: polyhedral inclusions (carboxysomes) of
      Thiobacillus neapolitanus.
AB  - The polyhedral inclusions of Thiobacillus neapolitanus have been isolated; they
      contain ribulose diphosphate carboxylase.

PMID- 4355680
TI  - Rapid viral induction of plasmacytomas in pristane-primed BALB-c mice.
AB  - Strain BALB/c mice were injected intraperitoneally with 0.5 milliliter of
      pristane, and 39 to 56 days later they were infected with Abelson murine leukemia
      virus, which is a lymphosarcomagenic variant of Moloney virus. Fifty-eight
      percent of the mice developed lymphosarcoma, and 28 percent developed
      immunoglobulin-producing plasmacytomas within 20 to 93 days (77 to 149 days after
      the pristane injection). Two of 57 control mice developed plasmacytomas at days
      138 and 166 after a single injection of pristane; no plasmacytomas were found in
      mice treated with virus alone.

PMID- 4355681
TI  - Collagen synthesis: localization of prolyl hydroxylase in tendon cells detected
      with ferritin-labeled antibodies.
AB  - An improved procedure was employed for linking ferritin to antibodies against
      prolyl hydroxylase, the enzyme that synthesizes the hydroxyproline in collagen.
      By electron microscopy, the enzyme was then found to be localized in cisternae of
      the rough endoplasmic reticulum of embryonic tendon cells; this indicates that
      hydroxylation of proline occurs while newly synthesized polypeptides are fed into
      the cisternae.

PMID- 4355682
TI  - [Anatomo-clinical and experimental study of paraquat poisoning. Ultrastructural
      lesions].

PMID- 4355683
TI  - [Histogenetic conclusions concerning diffuse interstitial fibrosis].

PMID- 4355684
TI  - [Diagnosis and educational trend in deafness in infancy].

PMID- 4355685
TI  - [Mediastinal emphysema and spasmophilia].

PMID- 4355687
TI  - [Historical evolution of the concept of the moderator check].

PMID- 4355686
TI  - [On the relations between intracerebral hematoma, mycotic aneurysm,
      staphylococcal septicemias and endocarditis].

PMID- 4355688
TI  - Gastric acid secretion in insulin-secreting tumors of the pancreas.

PMID- 4355689
TI  - Isolation of viable cells from experimental granulation tissue.

PMID- 4355690
TI  - IgM-producing malignant lymphomas without macroglobulinemia. Morphological and
      immunochemical findings.

PMID- 4355691
TI  - [Intranuclear bacteria in experimental listeria monocytogenes infections
      (author's transl)].

PMID- 4355693
TI  - The structure of the gill of the trout, Salmo gairdneri (Richardson).

PMID- 4355694
TI  - Effects of colchicine and vinblastine on neurotubules of the sciatic nerve and
      cholinesterases in the developing myoneural junction of the rat.

PMID- 4355692
TI  - A histochemical study of the inclusion bodies in the small intestine of the
      developing rat.

PMID- 4355695
TI  - Evidence for basal secretion in the subcommissural organ of the adult rabbit.

PMID- 4355696
TI  - Herpesvirus encephalitis following herpes keratitis.

PMID- 4355697
TI  - Congenital anomalies and herpesvirus infection.

PMID- 4355699
TI  - Vasoconstriction-volume analysis for understanding and treating hypertension: the
      use of renin and aldosterone profiles.

PMID- 4355698
TI  - Intracranial arterial occlusion in children. Diagnosis and follow-up by brain
      scanning.

PMID- 4355700
TI  - Searching out low renin patients: limitations of some commonly used methods.

PMID- 4355701
TI  - Renin, angiotensin and hypertensive vascular damage: a review.

PMID- 4355702
TI  - The control of renin release.

PMID- 4355703
TI  - Neurogenic factors in human hypertension: mechanism or myth?

PMID- 4355704
TI  - Hypertension in chronic renal failure. An abnormal relation between sodium and
      the renin-angiotensin system.

PMID- 4355705
TI  - Cushing's syndrome caused by recurrent malignant bronchial carcinod. Case report
      with 12 years' observation.

PMID- 4355707
TI  - Pressure synthesis of thioformamide.

PMID- 4355706
TI  - An experimental study of the effects of drains on colon anastomoses.

PMID- 4355708
TI  - Homogeneous catalysis by transition metal complexes. 3. A new cobalt-cyanide
      catalyst for selective homogeneous hydrogenation of dienes.

PMID- 4355709
TI  - [The antagonism exercised by Sandomigran (BC 105) on some properties of
      bradykinin].

PMID- 4355710
TI  - Dopamine-induced neurogenic vasodilatation: antagonism at the vascular level.

PMID- 4355711
TI  - Mechanism of the antihypertensive effect of 1-Sar-8-Ala-angiotensin II during the
      acute phase of experimental renal hypertension.

PMID- 4355714
TI  - Malignant mixed tumor of the lacrimal gland. Occult source of metastatic
      carcinoma.

PMID- 4355713
TI  - Ocular response to corticotropin in myasthenia gravis.

PMID- 4355712
TI  - Influence of vasoactive hormones on blood flow through the mammary artery in
      lactating cows.

PMID- 4355715
TI  - The role of vitamin D metabolites in bone resorption.

PMID- 4355716
TI  - Repolarization-induced reactivation of contracture tension in frog skeletal
      muscle.

PMID- 4355717
TI  - Pharmacologic receptor activity of rabbit aorta. Effect of dithiothreitol and N
      ethylmaleimide.

PMID- 4355718
TI  - Influence of acute stimuli on plasma aldosterone concentration in anephric man
      and kidney allograft recipients.

PMID- 4355720
TI  - A rapid competitive protein-binding assay of unconjugated oestradiol in late
      pregnancy plasma.

PMID- 4355719
TI  - [Biochemical study of the glycoproteins of the glomerulus basement membrane of
      the human kidney hydrolysed with collagenase (author's transl)].

PMID- 4355721
TI  - Determination of urinary amino acids by gas chromatography.

PMID- 4355722
TI  - Polyacrylamide gel electrophoresis as a method for differentiation and
      quantitation of serum enzymes hydrolysing phosphate monoesters.

PMID- 4355723
TI  - Biochemical properties of normal and neoplastic cell surfaces; a review.

PMID- 4355725
TI  - The cytotoxicity of chlorambucil and its associated effects on NAD metabolism.

PMID- 4355724
TI  - Wilm's tumour treated at the Rotterdam Radiotherapy Institute (1964-1971).

PMID- 4355726
TI  - Content of estrogen receptors in human breast cancer.

PMID- 4355727
TI  - Standards for the assessment of estrogen receptors in human breast cancer. Report
      of a workshop on September 29, 1972, at the Antoni van Leeuwenhoek-Huis,
      Amsterdam.

PMID- 4355728
TI  - The effects of PGE1 on responses to cardiac vagus nerve stimulation and
      acetylcholine release.

PMID- 4355729
TI  - Induction of stimulus-bound repetition in sympathetic ganglia by germine-mono
      acetate.

PMID- 4355730
TI  - Cyclic adenosine 3',5'-monophosphate concentration in rabbit parotid slices
      following stimulation by secretagotues.

PMID- 4355731
TI  - Prostaglandin release from vasculature by angiotensin II: dissociation from
      lipolysis.

PMID- 4355732
TI  - Synaptic biochemistry of amino acids.

PMID- 4355733
TI  - Studies of human amebiasis. I. Clinical and laboratory findings in eight cases of
      acute amebic colitis.

PMID- 4355734
TI  - Studies of human amebiasis. II. Light and electron-microscopic observations of
      colonic mucosa and exudate in acute amebic colitis.

PMID- 4355735
TI  - Rapid serological methods for the demonstration of Entamoeba histolytica
      activity.

PMID- 4355736
TI  - Letter: Effect of beta stimulant on eosinopenic responses.

PMID- 4355737
TI  - Chlorpromazine: effects of antacids on its gastrointestinal absorption.

PMID- 4355738
TI  - Neurite development in vitro. II. The role of microfilaments and microtubules in
      dibutyryl adenosine 3',5'-cyclic monophosphate and nerve growth factor stimulated
      maturation.

PMID- 4355739
TI  - Experimental inhibition of myelination in spinal cord tissue cultures: enzyme
      assays.

PMID- 4355741
TI  - Acute renal failure.

PMID- 4355740
TI  - Fasting hypoglycemia.

PMID- 4355742
TI  - [Therapy of infections with clonorchis sinensis (author's transl)].

PMID- 4355743
TI  - The response to chemical mutagens of the individual haploid and homoallelic
      diploid UV-sensitive mutants of the rad 3 locus of Saccharomyces cerevisiae.

PMID- 4355744
TI  - RNA-directed cell-free synthesis of the galactose enzymes of Escherichia coli.

PMID- 4355745
TI  - Cytoplasmic proteins regulating messenger RNA release from nuclei.

PMID- 4355747
TI  - Immunospecificity to non-histone chromosomal proteins of anti-chromatin
      antibodies.

PMID- 4355746
TI  - Discontinuous elongation of both strands at the replication forks in polyoma DNA
      replication.

PMID- 4355748
TI  - [Irradiation of cerebral gliomas, advantages of synthetic ACTH (synacthen)
      (author's transl)].

PMID- 4355749
TI  - The accumulation of 32P-polyphosphates of calcium, magnesium, lanthanum and
      sodium by tumor bearing animals: its radiotherapeutical significance.

PMID- 4355750
TI  - Photochemical labeling of yeast alcohol dehydrogenase with an azide analog of
      NAD+.

PMID- 4355751
TI  - Energy transfer between nucleic acid bases and tryptophan in aggregates and in
      oligopeptide-nucleic acid complexes.

PMID- 4355752
TI  - Effect of polymyxin B and endotoxin on renal cortical fibrinolysis.

PMID- 4355753
TI  - Evidence for glycosylated crosslinks in body-wall collagen of the sea cucumber,
      Thyome briareus.

PMID- 4355754
TI  - The role of adenine nucleotides and the effect of caffeine and dibutyryl cyclic
      AMP on the metabolism of guinea pig epididymal spermatozoa.

PMID- 4355755
TI  - Acid liability of rhinovirus type 14: effect of pH, time, and temperature.

PMID- 4355756
TI  - The effects of metyrapone and ACTH on the development of gluconeogenesis in the
      neonatal pig.

PMID- 4355757
TI  - Heterologous activity of monkey interferons.

PMID- 4355758
TI  - Nicotinamide adenine dinucleotide (NAD) content of liver with hemorrhagic shock.

PMID- 4355759
TI  - Influence of preinfection of C57BL-L mice with Graffi leukemia virus on 3
      methylcholanthren-induced subcutaneous sarcoma.

PMID- 4355760
TI  - Abortive herpes simplex virus replication in Rous sarcoma virus transformed
      cells.

PMID- 4355761
TI  - Pathogenetic studies of herpes simplex virus infection of the rabbit eye.

PMID- 4355763
TI  - [Therapy of epilepsy in infancy].

PMID- 4355762
TI  - Incorporation of a phospholipid precursor into the subcellular organelles of 9
      methylpteroylglutamic acid-treated rat embryos.

PMID- 4355764
TI  - [The alveolar cell carcinoma. II. Histomorphology, metastases, combination with
      other lung alterations and differential diagnosis (author's transl)].

PMID- 4355765
TI  - [Metabolism of water and sodium during normal pregnancy and pregnancy toxemia].

PMID- 4355766
TI  - [Recent data concerning the corticosteroid hormones].

PMID- 4355767
TI  - Enzymes of arginine and urea synthesis.

PMID- 4355769
TI  - Parainfluenza-3 and bovine enteroviruses as possible important causative factors
      in bovine abortion.

PMID- 4355768
TI  - The amidotransferases.

PMID- 4355770
TI  - Immunogenicity of canine distemper virus vaccine produced in a continuous cell
      line (LLC-MK2 cells).

PMID- 4355771
TI  - Bile duct carcinoma in cattle: three case reports.

PMID- 4355772
TI  - Correlation between TS phenotype and pathogenicity of some animal viruses.

PMID- 4355774
TI  - The effect of different media on maintenance of chick embryo tracheal organ
      cultures and replication of influenza virus. Brief report.

PMID- 4355773
TI  - Studies on reovirus type 2: viral interference with UV-inactived virus.

PMID- 4355775
TI  - [Characterization of membrane antigens from Zajdela-Hepatoma and normal rat liver
      (author's transl)].

PMID- 4355776
TI  - [Experimental study on cancerogenic haematotoxic and hepatotoxic activity of
      phosphor-organic pesticides (author's transl)].

PMID- 4355777
TI  - [The effect of norsteroid treatment on the histologic structure of mastopathic
      breast tissue (author's transl)].

PMID- 4355778
TI  - The influence of dipyridamol on changes in the heart induced with posterior
      pituitary extract.

PMID- 4355779
TI  - Case report of a familial oxalosis (ultrastructural study on the pathogenesis of
      kidney changes).

PMID- 4355780
TI  - Effect of antimycin A on hormone-stimulated lipolysis in vitro.

PMID- 4355782
TI  - Localization and characterization of the inhibitory action of ethacrynic acid on
      glycolysis.

PMID- 4355781
TI  - Effect of a single injection of betamethasone disodium phosphate on the synthesis
      of collagen and noncollagen protein of carrageenin granuloma in rats.

PMID- 4355783
TI  - Identification of (-)-delta 9-6a,10a-trans-tetrahydrocannabinol and two of its
      metabolites in rats by use of combination gas chromatography-mass spectrometry
      and mass fragmentography.

PMID- 4355784
TI  - The mode of action of beta-benzal butyric acid, an hypocholesterolemic drug, in
      affecting mitochondrial respiration.

PMID- 4355785
TI  - Effect of hydrocortisone acetate, fluocinolone acetonide, fluclorolone acetonide,
      betamethasone-17-valerate and fluprednyliden-21-acetate on collagen biosynthesis.

PMID- 4355786
TI  - Hepatic free radical levels in ethanol-treated and carbon tetrachloride-treated
      rats.

PMID- 4355787
TI  - Reaction of cytochrome c with one-electron redox reagents. I. Reduction of
      ferricytochrome c by the hydrated electron produced by pulse radiolysis.

PMID- 4355789
TI  - Electron spin resonance characterization of Chromatium D hemes, non-heme irons
      and the components involved in primary photochemistry.

PMID- 4355788
TI  - CO-binding pigments and the functional terminal oxidase of the trypanosomatid
      hemoflagellate Crithidia fasciculata.

PMID- 4355790
TI  - Nucleoside transport in normal and polyoma-transformed cells: kinetic differences
      following adenosine and serum or insulin stimulation.

PMID- 4355791
TI  - A rapid high yield method for the preparation of rat liver cell plasma membranes.

PMID- 4355793
TI  - Oxidative phosphorylation in immature rat brain mitochondria.

PMID- 4355792
TI  - Purification and properties of a nucleolar endoribonuclease from Novikoff
      hepatoma.

PMID- 4355794
TI  - The lipid composition of plasma lipoprotein density classes of sheep Ovis aries.

PMID- 4355795
TI  - Cyclic nucleotide phosphodiesterase from Tetrahymena.

PMID- 4355796
TI  - [Variation of the membrane potentials of cells of the caudate nucleus and
      thalamus in the presence of barbiturate spindles in rats].

PMID- 4355797
TI  - [The reactions of the large mesocerebral neurons of the mollusc Planorbis corneus
      to peripheral nerve stimulation].

PMID- 4355798
TI  - [Ganglionic behavior under conditions of experimental impairment of acetylcholine
      synthesis].

PMID- 4355800
TI  - Suppression of growth of L cells in suspension culture by dibutyrl adenosine
      3',5'-monophosphate.

PMID- 4355799
TI  - Inhibitory effect of streptonigrin on a murine sarcoma virus-induced tumor cell
      line (MSC) and selection of drug-resistant clones.

PMID- 4355802
TI  - Health planning as a managerial ideology.

PMID- 4355801
TI  - Selective detachment of mitotic cells by hypotonic salt solution.

PMID- 4355803
TI  - Aspects of adrenal function in neonatally estrogenized male mice.

PMID- 4355804
TI  - Active transport of 131-I across the blood-brain barrier.
AB  - The ventricular space of rabbits was perfused with a low-viscosity silicone oil
      for the purpose of (1) collecting freshly secreted cerebrospinal fluid (c.s.f.)
      uninfluenced by diffusional exchanges with the brain and (2) studying passage of
      solutes from the blood into the brain, uncomplicated by exchanges with c.s.f. The
      freshly secreted c.s.f. appeared as fine droplets suspended in the less dense
      silicone, and accumulated at the bottom of the collected silicone. Studies on the
      penetration of (24)Na from blood into this fluid indicated that considerable
      exchanges with the brain had occurred between its secretion and collection, in
      spite of this method of collection. The second objective was attained, in that
      the exchanges between the freshly secreted fluid and the brain were
      quantitatively insufficient to affect the measure of kinetics of uptake by brain
      from the blood. In consequence, it was possible to demonstrate unequivocally that
      the increased uptake by brain of (131)I, when treated with perchlorate, was due
      to inhibition of an active process occurring across the blood-brain barrier.
      Other studies, involving ventriculo-cisternal perfusion with artificial c.s.f.,
      lent further support to this concept. (131)I distribution is some 32% of the
      brain weight, a figure close to the ;chloride-space'.

PMID- 4355805
TI  - On the mechanism of halothane anaesthesia.
AB  - 1. The effects of halothane on the evoked potentials of in vitro preparations of
      guinea-pig olfactory cortex were studied.2. The evoked potentials recorded from
      the cortical surface comprised an initial diphasic wave - the lateral olfactory
      tract (l.o.t.) compound action potential - followed by a negative wave of 1-3 mV
      amplitude and about 10 msec duration. Superimposed on the negative wave was a
      number of positive peaks. The negative wave has been identified as an
      extracellularly recorded, monosynaptic, excitatory post-synaptic potential
      (e.p.s.p.) and the positive peaks have been shown to reflect the discharge of the
      cortical cell population in response to the evoked e.p.s.p. and are therefore
      termed ;population spikes'.3. When halothane (0.4-1.5%) was added to the gas
      stream that superfused the surface of the preparation the evoked e.p.s.p.s became
      smaller in amplitude and the size of the population spikes diminished. The l.o.t.
      compound action potential was unaffected by these levels of halothane. Higher
      levels of halothane (above 2%) further reduced the amplitude of the evoked
      e.p.s.p.s, abolished the population spikes, decreased the amplitude of the l.o.t.
      compound action potential and slowed its time course. The effects of halothane on
      the evoked potentials were dose-related and were independent (after the first 10
      min of treatment) of the duration of the exposure to halothane.4. The decrease in
      the size of the population spike caused by the exposure to halothane implied that
      transmission through the cortical relay had been impaired. This was also shown by
      the decrease in the evoked activity of units in the prepiriform cortex. Of eleven
      units, eight were depressed by halothane (0.5-1.5%) two were unaffected and one
      showed a transient increase in the number of spikes generated in response to a
      l.o.t. volley.5. Halothane (up to 1.5%) had no effect on the threshold of the
      l.o.t. fibres to electrical stimulation or on that of the post-synaptic cells to
      synaptic excitation.6. Post-tetanic potentiation and frequency potentiation of
      the evoked e.p.s.p.s were enhanced in the presence of 1% halothane.7. It is
      concluded that halothane reduces excitatory synaptic transmission not by an
      increase in the electrical threshold of the post-synaptic cells to synaptic
      excitation but by interference with the process of chemical transmission either
      by reducing the output of transmitter from the pre-synaptic nerve terminal or by
      reducing the sensitivity of the post-synaptic membrane to the released
      transmitter substance.

PMID- 4355807
TI  - Subcellular constituents of human placenta. I. Isolation and characterization of
      lysosomes from term tissue.

PMID- 4355806
TI  - Effect of insulin and epinephrine on the carbohydrate metabolism and adenylate
      cyclase activity of rhesus fetal muscle.

PMID- 4355808
TI  - [Alpha-fetoprotein in infectious hepatitis in children].

PMID- 4355809
TI  - Biosynthesis of steroids from cholesterol-14C by human adrenal carcinoma tissue.

PMID- 4355810
TI  - Steroids and steroidases XX (1). Aggregation in aqueous solution of steroids with
      stigmastane type C-17 side chains and its influence on their enzymic
      transformations.

PMID- 4355812
TI  - [Serological methods used in identification and characterization of the
      herpesvirus. I].

PMID- 4355811
TI  - Synthesis of 21-3H-corticosteroids.

PMID- 4355813
TI  - The renin axis in causation, prognosis and treatment of hypertensive disease.

PMID- 4355814
TI  - The carcinoembryonic antigen (CEA) in carcinomata of the stomach.

PMID- 4355816
TI  - [Otto Loewi, discoverer of chemical transmission of nerve impulses (author's
      transl)].

PMID- 4355815
TI  - [Ultrastructural study of the blue histocytes in a case of idiopathic lipidosis
      of the spleen with ceroid overload (author's transl)].

PMID- 4355817
TI  - Effect of ovarian hormones on lipid metabolism in different tissues of rats.

PMID- 4355818
TI  - Effect of imidazole on the adrenal response to ACTH and to stress.

PMID- 4355819
TI  - Investigations on the correlation between abnormalities of neuromuscular
      transmission due to some organophosphates and activity of acetylcholinesterase in
      the skeletal muscle.

PMID- 4355820
TI  - Clinical pharmacology of sleep: a critical review of all-night
      electroencephalographic studies.

PMID- 4355821
TI  - The effects of prostaglandin F2 alpha on the structure and function of the rabbit
      ovary.

PMID- 4355822
TI  - Morphological changes in the corpus luteum correlated with progestin levels in
      the rhesus monkey during early pregnancy.

PMID- 4355823
TI  - Mouse bone collagenase. The effect of heparin on the amount of enzyme released in
      tissue culture and on the activity of the enzyme.

PMID- 4355824
TI  - Propionin B, an antiviral principle of propionibacteria.

PMID- 4355825
TI  - Selective inactivation of the infectivity of freeze-dried Sendai virus by heat.

PMID- 4355826
TI  - [Von Zumbusch's generalized pustulous psoriasis and iodine hypersensitivity].

PMID- 4355827
TI  - Influence of plasma on ACTH stimulated corticosterone production of isolated
      adrenal cells.

PMID- 4355828
TI  - A new dental, ocular and cutaneous syndrome.

PMID- 4355829
TI  - Amoebiasis cutis.

PMID- 4355830
TI  - Rhabdoviruses.

PMID- 4355831
TI  - Viruses with double-stranded RNA genomes.

PMID- 4355832
TI  - A spin-label study of the role of phospholipids in the regulation of membrane
      bound microsomal enzymes.

PMID- 4355833
TI  - Studies of simian virus 40 DNA. VII. A cleavage map of the SV40 genome.

PMID- 4355834
TI  - A map of simian virus 40 transcription sites expressed in productively infected
      cells.

PMID- 4355835
TI  - Letter: Electron microscopic observation of DNA condensates at low pH values.

PMID- 4355837
TI  - Discharge and a discharge group.

PMID- 4355836
TI  - Adenovirus isolation from recurrent oral ulcers.

PMID- 4355838
TI  - Students learn to negotiate for role and demonstrate skill as group.

PMID- 4355839
TI  - Introduction of goal-oriented record keeping on an inpatient drug treatment
      setting.

PMID- 4355840
TI  - Evaluating mental health status with a simplified rating scale.

PMID- 4355841
TI  - The "sectorization" of comprehensive psychiatric services in France.

PMID- 4355842
TI  - Preventive aspects of the comprehensive psychiatric service in USSR.

PMID- 4355843
TI  - Meeting basic needs of the elderly.

PMID- 4355844
TI  - Speaking out: awash in freedom from hospitalization.

PMID- 4355846
TI  - The community mental health professional and the poor.

PMID- 4355845
TI  - Bacterial resistance to antibiotics.

PMID- 4355847
TI  - A forced-choice test for selecting psychiatric personnel.

PMID- 4355848
TI  - Correlation between the antiviral effect of interferon treatment and the
      inhibition of in vitro mRNA translation in noninfected L cells.
AB  - When noninfected L-cell suspension cultures are treated with interferon (specific
      activities superior to 10(6) reference units per mg of protein), the cell-free
      cytoplasmic extracts obtained are inactive for the translation of exogenous
      natural mRNAs. The dose-response curve shows that comparable amounts of
      interferon are required to produce a 50% reduction of Mengo virus multiplication
      in vivo and Mengo RNA translation in vitro. With higher doses of interferon,
      Mengo RNA translation is completely abolished, while poly U translation and
      endogenous protein synthesis are only slightly affected. The inactivation of
      Mengo RNA translation is reversible; after removal of interferon, normal
      translation activity is regained together with the ability to support Mengo virus
      multiplication. Fractionation of the cell-free extracts shows that the effect is
      localized in the fraction which can be washed off the ribosomes by high salt.
      These results establish that interferon induces a block in genetic translation in
      noninfected L cells.

PMID- 4355849
TI  - Chromatographic analyses of isoaccepting tRNAs from avian myeloblastosis virus.
AB  - Avian myeloblastosis virus (AMV) 4S RNA was tested for amino acid acceptor
      activity for 18 of the 20 amino acids. A nonrandom distribution of viral tRNAs
      was found compared with tRNA from normal liver or from AMV-infected leukemic
      myeloblasts, confirming previous reports. Methionine and proline tRNAs were
      considerably enriched, whereas glutamic acid, glutamine, serine, tyrosine, and
      valine tRNAs were markedly depleted in AMV relative to homologous cellular tRNAs.
      The seven AMV tRNAs with the greatest amino acid acceptance capacities, which
      were in order methionine, proline, lysine, arginine, histidine, isoleucine, and
      threonine tRNAs, were compared with homologous tRNAs from leukemic myeloblasts
      and liver by reversed-phase 5 chromatography. Of the 25 isoaccepting
      chromatographic fractions identified, no tRNA species unique to AMV was detected.
      Only methionyl-tRNA showed a substantial quantitative variation in isoaccepting
      species compared with the host cell. Thus, viral selectivity for amino acid
      specific tRNAs is not, generally, paralleled by selectivity for individual
      isoaccepting tRNA species. Qualitative differences in arginyl- and histidyl-tRNA
      isoaccepting species were discovered in virus and leukemic myeloblasts compared
      with liver. This indicates the existence of structural differences in these tRNA
      species which could be related to virus replication or expression.

PMID- 4355851
TI  - Acquisition of sequences homologous to host DNA by closed circular simian virus
      40 DNA. 3. Host sequences.
AB  - A preparation of serially passaged simian virus 40 (SV40) DNA, in which at least
      66% of the molecules contain covalently linked cellular DNA sequences, was
      digested to completion with the Hemophilus influenzae restriction endonuclease.
      Polyacrylamide gel electrophoresis of the digest showed that the majority of the
      cleavage products migrated as nine classes of fragments, each class defined by a
      particular molecular weight. These classes of fragments differ in molecular
      weight from the fragments produced by the action of the same enzyme on plaque
      purified virus DNA. Three classes of fragments were present in less than
      equimolar amounts relative to the original DNA. The remaining six classes of
      fragments each contain more than one fragment per original DNA molecule. DNA-DNA
      hybridization analysis (using the filter method) of the isolated cleavage
      products demonstrated the presence of highly reiterated cell DNA sequences in two
      of the nine classes of fragments. A third class of fragments hybridized with high
      efficiency only to serially passaged SV40 DNA; the level of hybridization to
      plaque-purified virus DNA was low and there was essentially no hybridization with
      cell DNA immobilized on filters. It is suggested that this class of fragments
      contains unique host sequences. It was estimated that at least 27% of the
      sequences in the substituted SV40 DNA molecules studied are host sequences. The
      majority of these are probably of the nonreiterated type.

PMID- 4355850
TI  - Acquisition of sequences homologous to host DNA by closed circular simian virus
      40 DNA. II. Further studies on the serial passage of virus clones.
AB  - Three plaque isolates of SV40 strain 777 and 1 plaque isolate of strain 776 were
      grown to high-titer stocks and serially passaged, undiluted, in monkey BS-C-1
      cells. In each case, the serial passaging procedure resulted in the accumulation
      of closed-circular SV40 DNA molecules containing covalently linked sequences
      homologous to reiterated host cell DNA (called substituted virus DNA). The
      relative yields, at a given passage level, of SV40 DNA with measurable homology
      to host DNA varied in different sets of serial passages, including passages of
      the same virus clone. More reproducible yields of substituted viral DNA progeny
      were obtained when the serial passaging procedure was initiated from earlier
      passages rather than from the original plaque-purified stock. Fractionation of
      closed-circular SV40 DNA molecules on alkaline sucrose gadients indicated that
      the majority of substituted virus DNA molecules are not plaque producers and are
      slightly smaller in size than plaque-forming DNA molecules which display no
      detectable homology to host DNA. Evidence that substituted SV40 DNA molecules
      replicate during serial undiluted passage was obtained from experiments which
      demonstrated (i) the presence of host sequences in replicative forms of the viral
      DNA and (ii) the incorporation of (3)H-thymidine into host sequences isolated
      from the mature substituted virus DNA molecule.

PMID- 4355852
TI  - Phosphorylation of animal virus proteins by a virion protein kinase.
AB  - Compared with several other enveloped viruses, purified virions of frog virus 3
      contained a relatively high activity of a protein kinase which catalyzed the
      phosphorylation of endogenous polypeptides or added substrate proteins. Virions
      also contained a phosphoprotein phosphatase activity which released phosphate
      covalently linked to proteins. It was possible to select reaction conditions
      where turnover of protein phosphoesters was minimal, as the phosphatase required
      Mn(2+) ions for activity whereas the protein kinase was active in the presence of
      Mg(2+) ions. Electrophoretic studies in polyacrylamide gels containing sodium
      dodecyl sulfate indicated that at least 10 of the virion polypeptides were
      phosphorylated in the in vitro protein kinase reaction. Characterization of these
      phosphoproteins demonstrated that the phosphate was incorporated predominantly in
      a phosphoester linkage with serine residues. The protein kinase was solubilized
      by disrupting purified virions with a nonionic detergent in a high-ionic-strength
      buffer and was separated from many of the virion substrate proteins by zonal
      centrifugation in glycerol gradients. The partially purified protein kinase would
      phosphorylate polypeptides of many different animal viruses, and maximal activity
      was not dependent on added cyclic nucleotides. These properties distinguished the
      virion protein kinase from a well characterized cyclic AMP-dependent protein
      kinase which phosphorylated viral proteins only to a small extent.

PMID- 4355854
TI  - Cleavage of poliovirus-specific polypeptide aggregates.
AB  - Zonal electrophoresis resolves two aggregates of poliovirus type 2 cytoplasmic
      polypeptides. The more negatively charged aggregate contains mainly noncapsid
      viral-specific polypeptides (NCVP) 2 and x, whereas the other consists of the
      capsid polypeptides (VP) 0, 1, 2, and 3 (VP0, VP1, VP2, VP3). After treatment
      with sodium deoxycholate (DOC), the aggregates sediment at 5 to 6S. Their
      electrophoretic mobilities are unaffected by DOC or RNase. The capsid polypeptide
      aggregate is similar in mobility to virions but can be converted to a faster
      electrophoretic form, resembling empty capsids, by heating. If infected HeLa
      cells are allowed to synthesize poliovirus polypeptides in the presence of
      iodoacetamide, no capsid polypeptides are produced, but rather NCVP1a (the
      precursor to capsid polypeptides) is accumulated, along with NCVP2 and NCVPx.
      When analyzed by electrophoresis and centrifugation, uncleaved NCVP1a migrates
      with the NCVP2-x aggregate. NCVP1a can be cleaved to capsid-like polypeptides in
      vitro by using extracts of infected cells, but not uninfected cells, indicating
      either a virus-specified protease or a cellular enzyme activated during
      infection. After cleavage of NCVP1a by infected cell extracts, the capsid
      polypeptides which are produced dissociate from the NCVP2-x complex.

PMID- 4355853
TI  - Separation of DNA sequences complementary to the RNA of avian myeloblastosis
      virus from chicken DNA by alkaline cesium chloride density sedimentation.
AB  - Density gradient sedimentation in alkaline cesium chloride of DNA from normal
      chicken embryos or leukemic myeloblasts fragmented to a size of 13S revealed that
      the DNA sequences complementary to 70S avian myeloblastosis virus RNA sedimented
      in the high guanine plus cytosine region ahead of the main peak of cellular DNA.
      When the DNA was fragmented into pieces of 6.6S there was a broader distribution
      of the DNA sequences complementary to the viral RNA. This technique could be
      employed as a step towards the isolation of DNA copies of the entire viral RNA
      genome from the mass of host cellular DNA.

PMID- 4355855
TI  - RNA synthesis in temperature-sensitive mutants of vesicular stomatitis virus.
AB  - T-particle-free stocks of temperature-sensitive mutants representing the four
      Glasgow complementation groups of the Indiana serotype of vesicular stomatitis
      virus were used to study RNA synthesis at the permissive and nonpermissive
      temperatures of 31 and 39 C, respectively. Mutants selected from the four Glasgow
      complementation groups were characterized on the basis of particle and
      ribonucleoprotein formation. Intracellular RNAs were further characterized by
      polyacrylamide gel electrophoresis. ts G22 (group II) and ts G41 (group IV),
      previously characterized as RNA negative at the nonpermissive temperature,
      synthesized low levels of RNA which could not be attributed to contaminating
      levels of revertants. Furthermore, the levels of synthesis could not be reduced
      by the addition of cycloheximide. These data suggest that ts G22 (group II) and
      ts G41 (group IV) contain a thermally stable, virion-encapsidated transcriptase,
      but fail to amplify RNA synthesis due to a thermally labile function presumably
      necessary for the synthesis of viral RNA. ts G31, a group III mutant, synthesized
      intracellular RNA at amplified levels at the nonpermissive temperature.
      Intracellular ribonucleoprotein complexes were isolated in copious amounts;
      however, no particles corresponding in size to finished virions were observed.
      These data suggest a thermally labile maturation factor or envelope associated
      structural protein to be defective in ts G31 (group III). ts G11 (group 1) showed
      no detectable RNA synthesis at the nonpermissive temperature. These data suggest
      ts G11 (group I) contains a thermally labile component involved in early
      transcription. This group may contain a number of mutants defective in different
      components of the transcription apparatus, which may not complement in vivo
      because of the physical improbability of subunit exchange between virion
      particles of the incoming inoculum.

PMID- 4355856
TI  - Gel electrophoresis of avian leukosis and sarcoma viral RNA in formamide:
      comparison with other viral and cellular RNA species.
AB  - Class a and class b 30 to 40S RNA subunits obtained by heat dissociation from the
      60 to 70S RNA complex of avian tumor viruses were compared with several RNA
      standards by electrophoresis in formamide-polyacrylamide gels. Class a RNA was
      found to have a lower electrophoretic mobility and hence probably a higher
      molecular weight than class b RNA. The absolute molecular weight of class a and b
      RNA could not be determined with accuracy, because the relationship between
      logarithm of molecular weight and mobility of the RNA standards was not linear.
      The size of class a RNA fell into the range of 2.4 x 10(6) to 3.4 x 10(6) daltons
      and that of class b into the range of 2.2 x 10(6) to 2.9 x 10(6) daltons,
      depending on the standards used. The possible biological significance of this
      difference is discussed.

PMID- 4355857
TI  - Hydroxyurea-induced accumulation of short fragments during polyoma DNA
      replication. I. Characterization of fragments.
AB  - Hydroxyurea treatment of 3T6 mouse fibroblast cells infected with polyoma virus
      resulted within 15 min in more than a 20-fold reduction of the rate of both viral
      and cellular DNA synthesis. After the initial rapid inhibition, the rate of DNA
      synthesis remained essentially constant for at least 2 h. In the inhibited cells
      viral DNA accumulated as short chains with a sedimentation coefficient of about
      4S (hydroxyurea fragments). A variable proportion of these fragments was released
      from the template strands when the viral DNA was extracted by the Hirt procedure.
      Reannealing experiments demonstrated that hydroxyurea fragments were polyoma
      specific and probably synthesized on both parental strands at the replication
      forks.

PMID- 4355858
TI  - Hydroxyurea-induced accumulation of short fragments during polyoma DNA
      replication. II. Behavior during incubation of isolated nuclei.
AB  - The synthesis of polyoma DNA was studied in isolated nuclei from hydroxyurea
      inhibited 3T6 cells infected with polyoma virus. During incubation of nuclei
      under conditions suitable for polyoma DNA synthesis in vitro, the short DNA
      fragments with a sedimentation coefficient of 4S formed in vivo (hydroxyurea
      fragments) became associated with preformed, replicating DNA strands.
      Centrifugation in dye-buoyant density gradients showed that the fragments formed
      part of the structure of the replicative intermediate of polyoma DNA. The
      proportion of "young" replicative intermediates was larger after hydroxyurea
      inhibition than in uninhibited controls. Hydroxyurea fragments appear to be
      closely related to the 4S fragments formed as normal intermediates during
      discontinuous synthesis of polyoma DNA.

PMID- 4355859
TI  - Envelope of mouse mammary tumor virus studied by freeze-etching and freeze
      fracture techniques.
AB  - As part of a study of the cell surface changes associated with the production of
      murine mammary tumor virus, the structure of the envelope of this virus has been
      examined by using freeze-fracture techniques. Both fracture and deep-etch
      surfaces were examined. The fracture faces contain 10-nm spheres comparable to
      those observed on fractured plasma membranes, although fewer in number. Surfaces
      exposed by etching possess a highly regular hexagonal array of pits 25 nm apart.
      By examining freeze-fracture and freeze-etch preparations of virus with ferritin
      covalently bound to its surface, it has been determined that the surface exposed
      by etching is the outer surface of the virus. The pitted exterior surface of the
      mammary tumor virus appears to be a unique surface structure.

PMID- 4355860
TI  - Human papovavirus, BK strain: biological studies including antigenic relationship
      to simian virus 40.
AB  - Some of the properties of a new human papovavirus, BK, have been examined. Host
      range studies of BK virus (BKV) showed human cells to be more sensitive to
      infection than monkey cells; human fetal brain cells appear to be highly
      sensitive to BKV, with the production of extensive cytopathology characterized by
      cytoplasmic vacuolization. The hemagglutinin of BKV is associated with the virion
      and is resistant to ether or heating at 56 C for 30 min. Fluorescent antibody as
      well as neutralization tests indicated antigenic similarities between simian
      virus 40 (SV40) and BKV. Cells undergoing lytic infection with BKV synthesized
      intranuclear T antigen(s) which reacted with SV40 T antibody demonstrable by
      immunofluorescence. However, BKV did not appear to induce SV40 transplantation
      antigens in transplantation-resistance tests. Evidence was obtained that BKV was
      present in humans prior to the widespread use of polio vaccines, thus ruling out
      the possibility that BKV is an SV40-related monkey virus, introduced into the
      human population by accidental contamination of poliovirus vaccines.

PMID- 4355861
TI  - Use of nondefective adenovirus-simian virus 40 hybrids for mapping the simian
      virus 40 genome.
AB  - A series of viable recombinants between adenovirus 2 (Ad2) and simian virus 40
      (SV40) (nondefective Ad2-SV40 hybrids) have been isolated. The members of this
      series (designated Ad2(+)ND(1) through Ad2(+)ND(5)) differ from one another in
      the early SV40-specific antigens and the SV40-specific RNA species which they
      induce in infected cells. They also contain different amounts of SV40 DNA as
      shown by RNA-DNA hybridization techniques. We have examined the structure of the
      DNA molecules from these hybrids, using electron microscope heteroduplex mapping
      techniques. Each hybrid was found to contain a single segment of SV40 DNA of
      characteristic size covalently inserted at a unique location in the adenovirus 2
      DNA molecule. The SV40 segments of the various hybrids formed an overlapping
      series with a common end point. When the results of the electron microscopic
      study were combined with data on antigen induction, it was found that a self
      consistent map could be constructed which related specific regions of the SV40
      genome to the induction of specific antigens. The order of these early SV40
      antigen inducing regions in the SV40 DNA segments contained in the nondefective
      hybrids is: U antigen, tumor specific transplantation antigen, and T antigen with
      the U antigen region being nearest the common end point.

PMID- 4355862
TI  - Mapping of simian virus 40 early functions on the viral chromosome.
AB  - The simian virus 40 (SV40) DNA segment in the nondefective adenovirus 2-SV40
      hybrid, Ad2(+)ND(4), is colinear with the segment between 0.11 and 0.59 SV40
      fractional length from the site at which the R(1) restriction endonuclease
      cleaves SV40 DNA. This specifies the region of the SV40 DNA molecule which
      induces the early SV40 antigens: U antigen, tumor specific transplantation
      antigen, and T antigen. A variant of Ad2(+)ND(4), called Ad2(+)ND(4del), was
      found which has a deletion of the DNA segment between 0.50 and 0.57 SV40
      fractional length from the R(1) endonuclease cleavage point.

PMID- 4355863
TI  - Growth of pseudotypes of vesicular stomatitis virus with N-tropic murine leukemia
      virus coats in cells resistant to N-tropic viruses.
AB  - Formation of pseudotypes between murine RNA tumor viruses and vesicular
      stomatitis virus (VSV) has been confirmed. Pseudotypes of VSV genomes coated by
      the surface envelope from an N-tropic tumor virus grew equally well in cells
      homozygous for either the Fv-1(n) or Fv-1(b) alleles. Therefore, the product of
      the Fv-1 locus, which restricts growth of murine RNA tumor viruses, must act on
      an intracellular aspect of tumor virus replication, a step after attachment and
      penetration.

PMID- 4355864
TI  - Proposed nomenclature for mutants of adenoviruses.
AB  - In accord with the nomenclature proposed for mutants of simian virus 40 the same
      rules, with minor modifications, are recommended for naming mutants of
      adenoviruses. It is further suggested that these rules, which pertain to a system
      of classification based primarily upon complementation analysis, also be applied
      to mutants of other DNA-containing animal viruses.

PMID- 4355865
TI  - Improved technique for the isolation of temperature-sensitive mutants of foot-and
      mouth disease virus.
AB  - An improved temperature-shift selection and screening method is described for the
      isolation of temperature-sensitive mutants of foot and mouth disease virus.

PMID- 4355866
TI  - [Cytochemical and immunological determinations in chronic lymphocytic leukemia].

PMID- 4355868
TI  - An inexpensive apparatus facilitating the storage of oxygen sensitive compounds.

PMID- 4355869
TI  - Preparative electrophoresis of living mammalian cells in a stationary ficoll
      gradient.

PMID- 4355867
TI  - A rapid and reproducible homogenization procedure for the isolation of plasma
      membranes from rat liver.

PMID- 4355870
TI  - [Karyokinesis and nuclear morphology during hepatocarcinogenesis. II. The fine
      structure of the nuclei in hepatocytes and hepatoma cells of the
      nitrosomorpholine-intoxicated rat liver (author's transl)].

PMID- 4355871
TI  - Chlorphentermine-induced ultrastructural changes in liver tissues of four animal
      species.

PMID- 4355872
TI  - [Parabiosis experiments for demonstrating the origin of fibroblasts within the
      CNS. Autoradiographical studies after siliceous acid implantation (author's
      transl)].

PMID- 4355873
TI  - Vinblastine-induced paracrystals and unusually large microtubules (macrotubules)
      in rat renal cells.

PMID- 4355874
TI  - Intercellular contact in the unincubated chick embryo.

PMID- 4355875
TI  - Fine structure of the developing spore of Nosema apis Zander.

PMID- 4355876
TI  - Fluorescence histochemical and ultrastructural observations on the effects of
      intravenous injections of vinblastine on noradrenergic nerves.

PMID- 4355877
TI  - Effects of parathyroid hormone on osteoclasts in vivo. An ultrastructural and
      histochemical study.

PMID- 4355878
TI  - Structure and innervation of the pineal gland of the rabbit, Oryctolagus
      cuniculus (L.). II. An electron microscopic investigation of the pinealocytes.

PMID- 4355879
TI  - Histological and ultrastructural observations on wound healing in the freshwater
      pulmonate Lymnaea stagnalis.

PMID- 4355880
TI  - Morphologic observations of brain tumors in PD4 hamsters induced by four strains
      of avian sarcoma virus.

PMID- 4355881
TI  - Pseudocroup with stridor.

PMID- 4355882
TI  - Ultrastructural study of the human anterior pituitary. Preliminary results.

PMID- 4355883
TI  - Effects of mammalian corticotrophin on the ultrastructure of presumptive
      interrenal cells in the opisthonephros of the lamprey, Petromyzon marinus L.

PMID- 4355884
TI  - Spontaneous and light-induced compound action potentials in the isolated eye of
      Aplysia: initiation and synchronization.

PMID- 4355885
TI  - Dose effects of cortisol on single unit activity in hypothalamus, reticular
      formation and hippocampus of freely behaving rats correlated with plasma steroid
      levels.

PMID- 4355886
TI  - Microelectrophoretic studies on the depressant action of HA-966 on chemically and
      synaptically excited neurones in the cat cerebral cortex and cuneate nucleus.

PMID- 4355888
TI  - Equivalence of synaptic and injected current in determining the membrane
      potential trajectory during motoneuron rhythmic firing.

PMID- 4355887
TI  - Effects of prostaglandins E1, E2 and F2a on cyclic AMP levels in brain in vivo.

PMID- 4355889
TI  - Masseteric reflex response to reticular stimulation reverses during active sleep
      compared with wakefulness or quiet sleep.

PMID- 4355890
TI  - High affinity uptake of cyclic AMP in rat brain slices.

PMID- 4355891
TI  - Electron paramagnetic resonance (34 and 55 GHz) studies of hemoproteins.

PMID- 4355893
TI  - Nucleotide clusters in deoxyribonucleic acids. 8. The pyrimidine oligonucleotides
      of bacteriophage S13 wild type DNA.

PMID- 4355892
TI  - Synthesis of glycerol-1,3-diphosphonic acid.

PMID- 4355894
TI  - [Reflections on 4 years of medical practice in the African bush].

PMID- 4355895
TI  - Amebiasis: a ten-year review of clinical and epidemiological progress in the
      Saskatchewan endemic area.

PMID- 4355896
TI  - [Demonstration of beta-lipoproteins in patients with chronic hepatitis by beta-L
      test (author's transl)].

PMID- 4355898
TI  - Pseudomonas bacterial endocarditis. A case report.

PMID- 4355897
TI  - Serum phospholipids in children with familial hypercholesterolaemia.

PMID- 4355899
TI  - A role for ferritin in the regulation of iron metabolism.

PMID- 4355900
TI  - Dogfish lactate dehydrogenase. The stereochemistry of hydrogen transfer.

PMID- 4355902
TI  - Inactivation of ADH from yeast and GAPDH from rabbit muscle by structural
      analogues of NAD.

PMID- 4355901
TI  - The presence of lactic acid in purified lactate dehydrogenase.

PMID- 4355903
TI  - [In vitro synthesis of progesterone in human cyclic corpus luteum: action of
      prostaglandin F2alpha].

PMID- 4355904
TI  - A study on the cleavage site specificity of the endonuclease associated with
      purified simian virus 40 particles.

PMID- 4355905
TI  - Studies on the metabolism of cyclic nucleotides by the toad bladder: the
      metabolic products of cAMP.

PMID- 4355906
TI  - The production of cIMP by toad bladder, and its effects on transport of water and
      salt.

PMID- 4355907
TI  - Butanol-soluble glycosyl transferases in Klebsiella aerogenes.

PMID- 4355908
TI  - Cytochrome c (553, Chlorobium thiosulfatophilum) is a sulphide-cytochrome c
      reductase.

PMID- 4355909
TI  - The influence of Mg2+-adenine nucleotide ratios and absolute concentration of
      Mg2+-adenine nucleotide on the observed velocity of some kinase reactions.

PMID- 4355910
TI  - Influence of uncouplers on succinate-cytochrome c reductase.

PMID- 4355912
TI  - The chemotactic effect of cyclic nucleotides with substitutions in the base ring.

PMID- 4355911
TI  - Distribution of insulin receptor sites among liver plasma membrane subfractions.

PMID- 4355913
TI  - Action of human skin collagenase on cartilage collagen.

PMID- 4355914
TI  - Purification by affinity chromatography of thermostable glyceraldehyde 3
      phosphate dehydrogenase from Thermus aquaticus.

PMID- 4355915
TI  - Formation of guanosine tetraphosphate (magic spot I) in homologous and
      heterologous systems.

PMID- 4355916
TI  - Depolarization induced calcium release from sarcoplasmic reticulum membrane
      fragments by changing ionic environment.

PMID- 4355918
TI  - [UV sanitation of the air and surfaces for the purpose of preventing in-hospital
      viral respiratory infections].

PMID- 4355917
TI  - Does formylation of initiator tRNA act as a regulatory signal in E. coli?

PMID- 4355919
TI  - Nutritional correlates of child development in Southern Tunisia. 3. Skeletal
      growth and maturation.

PMID- 4355920
TI  - Collagenase activity in cutaneous scars.

PMID- 4355921
TI  - On the mechanism of radioprotection by cysteamine. II. The significance of cyclic
      3',5'-AMP for the cysteamine-induced radioprotective effects in white mice.

PMID- 4355922
TI  - Letter: E.s.r. studies on gamma-irradiated TAN (triacetoneamine n-oxyl) radicals.

PMID- 4355923
TI  - A rapid technique for obtaining one-step or multi-step antibiotic resistant
      mutants employing mutator strains of Escherichia coli K12.

PMID- 4355924
TI  - Mitochondrial biogenesis during differentiation of Artemia salina cysts.
AB  - Mitochondria isolated from cysts of Artemia salina (brine shrimp) were found to
      be devoid of cristae and to possess a low respiratory capability. Hydration of
      the cysts induces marked biochemical and morphological changes in the
      mitochondria. Their biogenesis proceeds in two stages. The first stage is
      completed within 1 h and is characterized by a rapid increase in the respiratory
      capability of the mitochondria, their cytochrome oxidase, cytochrome b,
      cytochrome c and perhaps some morphological changes. In the second stage there is
      an increase in the protein-synthesizing capacity of the mitochondria as well as
      striking changes in mitochondrial morphology leading to the formation of cristae.

PMID- 4355925
TI  - Antivirals. 1. 2-(Alpha-hydroxybenzyl)imidazo(4,5-C)pyridine.

PMID- 4355926
TI  - Iodination of estrogen receptors in rat uterine eosinophils.

PMID- 4355927
TI  - Effect of ampicillin treatment on the urinary excretion of estriol conjugates in
      pregnancy.

PMID- 4355928
TI  - Oncogenic transformation of hamster embryo cells after exposure to inactivated
      herpes simplex virus type 1.
AB  - The in vitro transformation of hamster embryo fibroblasts by herpes simplex virus
      type 1 (HSV-1) after exposure of the virus to UV irradiation is described. Cell
      transformation was induced by 2 out of 12 strains of HSV-1 that were tested for
      transforming potential. Cells transformed by the KOS strain of HSV-1 were not
      oncogenic when injected into newborn Syrian hamsters. However, cells transformed
      by HSV-1 strain 14-012 induced tumors in 47% of the newborn hamsters injected.
      HSV-specific antigens were found in the cytoplasm of cells transformed by both
      virus strains. Sera from tumor-bearing hamsters contained HSV-1- and HSV-2
      neutralizing antibodies as well as antibodies which reacted specifically with HSV
      antigens by the indirect immunofluorescence technique. Hamster oncornavirus
      antigens were not detected by immunofluorescence methods. These observations
      represent the first evidence of the oncogenic potential of HSV-1.

PMID- 4355929
TI  - Hydroxyapatite chromatography and formamide denaturation of adenovirus DNA.
AB  - Denatured adenovirus DNA was retained by hydroxyapatite columns under conditions
      generally used for selective retention of double-stranded DNA, probably due to
      several partially complementary sequences within single-stranded DNA. It was
      found that addition of formamide reduced the fraction of sonically treated,
      denatured adenovirus DNA bound to hydroxyapatite from about 30% to less than 1%.
      This led to a study of the effect of formamide on the melting temperature (T(m))
      of double-stranded DNA in solution or bound to hydroxyapatite. The T(m) of DNA
      decreases 0.56 C/1% formamide, a value determined in buffered solutions with
      purified formamide.

PMID- 4355930
TI  - RNA synthesis by vesicular stomatitis virus and a small plaque mutant: effects of
      cycloheximide.
AB  - The synthesis of viral RNA by wild-type vesicular stomatitis virus (L(1)VSV) and
      a small, plaque-size mutant (S(2)VSV) was studied in vitro and in chicken embryo
      (CE) and mouse L-cell cultures. Virus-specific RNA synthesized in CE or L cells
      infected with either L(1) or S(2)VSV at low multiplicity was of the same size
      classes, 12 to 15S, 28S, and 38S. The major differences were in the proportion of
      RNA produced of each size class. L(1)VSV always synthesized larger proportions of
      38S RNA, and S(2)VSV produced larger proportions of 12 to 15S RNA. Both S(2) and
      L(1)VSV exhibited RNA transcriptase activity in vitro and in cell culture. The
      products of the in vitro reaction were the same, 12 to 15S for both. The products
      of the virion-associated transcriptase in CE or L-cell cultures in the presence
      of cycloheximide were also the same for both viruses but differed from the in
      vitro products in that 28S and 12 to 15S RNA were made. The effects of addition
      of cycloheximide at various times after infection demonstrated that new protein
      synthesis is required early (0-2 h) for both S(2) and L(1)VSV to initiate and
      maintain the normal rate of viral RNA synthesis. However, the overall rate of RNA
      synthesis in L(1)VSV infections became independent of protein synthesis after 2 h
      whereas the rate in S(2)VSV infections did not. With either virus, synthesis of
      38S RNA did not occur in the absence of protein synthesis. Moreover, continuous
      38S RNA production required continuous protein synthesis. Production of 38S RNA
      ceased within 30 min after addition of cycloheximide to S(2) (-) or L(1)VSV
      infected CE or L cells that had already begun to synthesize the 38S form. The
      cycloheximide-induced cessation of 38S RNA synthesis was accompanied by a marked
      increase in production of 12 to 15S and 28S RNA in L(1)VSV-infected cells, but no
      increase in synthesis of small RNA species occurred in S(2)VSV-infected cells.

PMID- 4355931
TI  - In vitro protein-synthesizing activity of vesicular stomatitis virus-infected
      cell extracts.
AB  - Crude cytoplasmic extracts from vesicular stomatitis virus (VSV)-infected HeLa
      cells incorporate radioactive amino acids into hot trichloroacetic acid
      precipitable material linearly for 10 to 20 min. The material synthesized in
      vitro corresponds in molecular weight to four of the five VSV structural
      proteins. However, synthesis of the viral glycoprotein (G) is significantly
      reduced, whereas the relative amounts of viral structural proteins L and NS
      synthesized are increased compared with the ratio of the proteins found in the
      virion. Fractionation of a VSV-infected crude cytoplasmic extract into a
      cytoplasmic pellet (20,000 x g for 30 min) and a cytoplasmic supernatant results
      in a significant reduction in protein synthesizing activity of both fractions,
      although both contain polysomes. The products synthesized by a cytoplasmic
      supernatant-directed system included all the VSV structural proteins except the
      glycoprotein, whereas in an in vitro system directed by the cytoplasmic pellet
      there is a marked reduction in synthesis of the nucleoprotein (N) and also a
      small relative increase in synthesis of the glycoprotein. Addition of uninfected,
      preincubated HeLa or L-cell S10 or a HeLa ribosomal fraction to the VSV-infected
      cytoplasmic pellet results in a 30- to 60-fold stimulation of (35)S-methionine
      incorporation. However, these uninfected extracts do not stimulate (35)S
      methionine incorporation by the infected crude cytoplasmic extract or the
      cytoplasmic supernatant. The products synthesized by the stimulated cytoplasmic
      pellet now include sizeable amounts of the glycoprotein in addition to the other
      VSV structural proteins.

PMID- 4355932
TI  - Mechanism of oncogenic transformation by Rous sarcoma virus. 3. Role of proviral
      DNA in morphologic conversion of chicken embryo fibroblasts.
AB  - Multiplication of Rous sarcoma virus and morphological conversion of chicken
      embryo fibroblasts are mediated by a DNA provirus. The role of the provirus in
      induction of morphological conversion has been shown by experiments of light
      inactivation of bromodeoxyuridine (BUdR)-sensitized proviral DNA. In the
      experiments reported here, inactivation of focus formation by BUdR and light
      could be obtained in cells in which the ability to produce virus has become
      resistant to X irradiation. This property is considered here to reflect the
      integrated state of the provirus. These experiments indicate that the role of
      proviral DNA extends beyond induction of morphological conversion and that an
      intact provirus is required for the maintenance of the transformed state. These
      experiments also indicate that no irreversible process leading to morphological
      conversion is initiated by a nonintegrated or by an integrated provirus.

PMID- 4355933
TI  - Polypeptide composition of poliovirions, naturally occurring empty capsids, and
      14S precursor particles.
AB  - The three serotypes of poliovirus were compared with respect to their polypeptide
      composition. Type 1, 2, and 3 strains were clearly different from each other in
      the electrophoretic mobilities of their larger structural polypeptides. Some of
      the viral polypeptides formerly identified as single peaks (e.g., VP 2) were
      shown to contain multiple components, indicating that purified virions contain at
      least six polypeptides. Three type 1 strains were indistinguishable in their
      viral polypeptides. A quantitative estimate was made of the polypeptide
      composition of the type 1 Mahoney poliovirion, as well as of naturally occurring
      empty capsids and 14S precursor particles. The data are discussed in light of the
      antigenic differences among polioviruses and the possible modes of virion
      morphogenesis.

PMID- 4355934
TI  - Membrane proteins of uninfected and Rous sarcoma virus- transformed avian cells.
AB  - A method for preparing large membrane fragments and cell ghosts was developed for
      uninfected and Rous sarcoma virus-transformed chicken embryo fibroblasts in
      culture. Membrane proteins were analyzed by electrophoresis in acrylamide gels
      containing sodium dodecyl sulfate. A major amino-acid-containing component of
      uninfected cell membranes was greatly diminished in amount or absent in membranes
      of virus-transformed cells. This component, called MP-1, had an electrophoretic
      mobility in sodium dodecyl sulfate-containing gels similar to that of a protein
      of a mol wt of 1.42 x 10(5). MP-1 was not altered by changes in cell growth rate
      or in cells infected with the nontransforming virus RAV-1.

PMID- 4355935
TI  - Characterization of the low-molecular-weight RNAs associated with the 70S RNA of
      Rous sarcoma virus.
AB  - Two low-molecular-weight RNAs are associated with the 70S RNA complex of Rous
      sarcoma virus: a previously described 4S RNA and a newly identified 5S RNA. The
      4S RNA constitutes 3 to 4% of the 70S RNA complex or the equivalent of 12 to 20
      molecules per 70S RNA. It exhibits a number of structural properties
      characteristic of transfer RNA as revealed by two-dimensional electrophoresis of
      oligonucleotides obtained from a T1 ribonuclease digest of the 4S RNA species.
      The 5S RNA is approximately 120 nucleotides in length, constitutes 1% of the 70S
      RNA complex or the equivalent of 3 to 4 molecules per molecules of 70S RNA, and
      is identical in nucleotide composition and structure to 5S RNA from uninfected
      chicken embryo fibroblasts. Melting studies indicate that the 5S RNA is released
      from the 70S RNA complex at the same temperature required to dissociate 70S RNA
      into its constituent 35S subunits. In contrast, greater than 80% of the 4S RNA is
      released from 70S RNA prior to its conversion into subunits. The possible
      biological significance of these 70S-associated RNAs is discussed.

PMID- 4355936
TI  - Isolation of mutants of bacteriophage T4 unable to induce thymidine kinase
      activity.
AB  - New mutants of T4 have been isolated by using a strain of Escherichia coli
      lacking thymidine kinase activity. These T4 mutants, designated tk, are able to
      grow on this E. coli strain under light on plates containing 5-bromodeoxyuridine
      and were all found to be unable to induce thymidine kinase (ATP: thymidine 5'
      phosphotransferase, EC 2.7.1.21). All of these tk mutants fall into one
      complementation group which maps just to the right of rI on the standard T4
      genetic map, far from most other genes coding for enzymes involved in pyrimidine
      metabolism. The tk mutants grow as well as wild-type T4, indicating that
      thymidine kinase is a non-essential enzyme.

PMID- 4355938
TI  - The use of estrogen as a postcoital contraceptive in North Carolina--trick or
      treatment.

PMID- 4355937
TI  - [On the renal action of angiotensin II in man. Direct and indirect effects].

PMID- 4355939
TI  - [Recurrent Abrikossov's tumor of the vulva].

PMID- 4355940
TI  - Long term survivor in metastatic colonic carcinoma to the brain.

PMID- 4355941
TI  - Effects of sex hormones on sleep patterns of male rats gonadectomized in
      adulthood and in the neonatal period.

PMID- 4355942
TI  - [Polygraphic study of vigilance states in the guinea pig fetus].

PMID- 4355943
TI  - [Temporal characteristics of the augmentation of paradoxal sleep following
      learning in the rat].

PMID- 4355945
TI  - Insulitis in cytomegalovirus infection in a newborn infant.

PMID- 4355944
TI  - Pituitary-adrenocortical activity and intermale aggressiveness in isolated mice.

PMID- 4355946
TI  - Contrast filling of the lymphatic system of the lung through a pulmonary vein in
      the dog.

PMID- 4355947
TI  - Effect of alcohol on albumin synthesis by the isolated perfused rat liver.

PMID- 4355948
TI  - Delayed radiation necrosis of the optic nerve.

PMID- 4355949
TI  - Adult cytomegalic inclusion retinitis.

PMID- 4355950
TI  - Roentgenologic demonstration of spontaneous reversal of portal blood flow in
      cirrhosis and primary carcinoma of the liver.

PMID- 4355951
TI  - A quantitative serologic assay for diagnosing congenital infections of cattle.

PMID- 4355952
TI  - Passive immunity in the foal: measurement of immunoglobulin classes and specific
      antibody.

PMID- 4355953
TI  - Calcium pyrophosphate dihydrate crystal deposition in neuropathic joints. Four
      cases of polyarticular involvement.

PMID- 4355954
TI  - Clinical conference: Essential hypertension: new concepts about mechanisms.

PMID- 4355955
TI  - Letter: Cytomegalovirus mononucleosis with severe thrombocytopenia.

PMID- 4355956
TI  - [Thermosensitive mutants of vesicular stomatitis virus of complementation group
      II (author's transl)].

PMID- 4355957
TI  - Conversion of hydrocortisone to estrogen in carcinoma of the breast after
      oophorectomy and adrenalectomy.

PMID- 4355959
TI  - Breast xeroradiography: an analysis of our first 17 months.

PMID- 4355958
TI  - Role of hepatic bile composition in gallstone formation in baboons.

PMID- 4355960
TI  - Substrate specificity of mammalian D-glucuronolactone dehydrogenase.

PMID- 4355961
TI  - A serological study of bovine foetal immunoglobulins.

PMID- 4355962
TI  - Coccidiosis in chickens: obligate relationship between Eimeria tenella and
      certain species of cecal microflora in the pathogenesis of the disease.

PMID- 4355963
TI  - An experimental study of the pathogenesis of fowlpox infection in chickens.

PMID- 4355964
TI  - Immunization of chickens with an inactivated oil-adjuvant Newcastle disease virus
      vaccine.

PMID- 4355965
TI  - Research note--avian encephalitis virus as a chicken kidney cell-culture
      contaminant and its effect on the growth of infectious bronchitis virus.

PMID- 4355966
TI  - Radiation-induced pair-wise radical formation in single crystals of thymine.

PMID- 4355967
TI  - Structural studies of avian myeloblastosis virus: presence of transfer RNA in
      core component.

PMID- 4355968
TI  - Partial purification of a cyclic AMP phosphodiesterase from soybean callus.
      Isolation of a non-dialysable inhibitor.

PMID- 4355969
TI  - Metabolic enzymes in liver and kidney of the germfree rat.

PMID- 4355970
TI  - The effects of insulin, serum and glucose on total assayable activity and on
      soluble, debris-bound and latent activity of the hexokinase of normal- and
      polyoma virus-transformed BHK 21 cells.

PMID- 4355971
TI  - Long-term aftercare for patients treated for thyrotoxicosis.

PMID- 4355972
TI  - Electron microscope study of antigens in cells of mouse mammary tumor cell lines
      by peroxidase-labeled antibodies in sera of mammary tumor-bearing mice and of
      patients with breast cancer.

PMID- 4355973
TI  - Paramagnetic changes during development of a transplanted AKR-J leukemia in mice
      as measured by electron spin resonance.

PMID- 4355974
TI  - Seroepidemiological studies on carcinoma of the nasopharynx.

PMID- 4355975
TI  - Quantitative estimations of RNA sensitive to mild RNase treatment in sections of
      normal, regenerating, and neoplastic rat livers.

PMID- 4355976
TI  - Effects of dimethylbenz(a)anthracene and dihydrotestosterone on estradiol-17 beta
      binding in rat mammary cytosol fraction.

PMID- 4355977
TI  - Specific glucocorticoid binding in human hemopoietic cell lines and neoplastic
      tissue.

PMID- 4355978
TI  - Absence of aminonucleoside-sensitive steps in the cell cycle of SV40-transformed
      human fibroblasts.

PMID- 4355980
TI  - The content of the principal protein target of a hepatic carcinogen in liver
      tumors.

PMID- 4355979
TI  - Some properties of adenyl cyclase from Ehrlich tumor cells.

PMID- 4355981
TI  - Two-dimensional gel electrophoresis of acid-soluble nucleolar proteins of Walker
      256 carcinosarcoma, regenerating liver, and thioacetamide-treated liver.

PMID- 4355982
TI  - Methylhydrazine tumorigenesis in Syrian golden hamsters and the morphology of
      malignant histiocytomas.

PMID- 4355983
TI  - Specific estrogen binding in vivo in the R3230AC mammary adenocarcinoma of the
      rat.

PMID- 4355984
TI  - Insulin reversal of growth inhibition of plasma cell tumor by prostaglandin or
      adenosine 3',5'-monophosphate.

PMID- 4355985
TI  - Increased sialic acid density in surface glycoprotein of transformed and
      malignant cells--a general phenomenon?

PMID- 4355986
TI  - Catabolism of nuclear proteins in control and phytohemagglutinin-stimulated human
      lymphocytes, leukemic leukocytes, and Burkitt lymphoma cells.

PMID- 4355987
TI  - Spectrophotometric analysis of cytochromes in Morris hepatomas.

PMID- 4355988
TI  - Combined enzyme histochemical and radioautographic studies on areas of
      hyperplasia in the liver of rats fed N-2-fluorenylacetamide.

PMID- 4355990
TI  - Effects of formamidoxime on macromolecular synthesis in regenerating liver and
      hepatomas.

PMID- 4355989
TI  - Effects of riboflavin deficiency upon concentrations of riboflavin, flavin
      mononucleotide, and flavin adenine dinucleotide in Novikoff hepatoma in rats.

PMID- 4355991
TI  - The effect of silica dust on the phospholipid metabolism of macrophages.

PMID- 4355992
TI  - Estimation of inorganic pyrophosphate phosphohydrolytic activity in human blood
      serum. The effects of serum constituents, magnesium and calcium.

PMID- 4355993
TI  - 17(OH) corticosteroid and estrogen excretion with virilizing adrenal tumors.

PMID- 4355994
TI  - Interaction of various stimulators and inhibitors on insulin secretion in vitro.

PMID- 4355995
TI  - Electric stimulation of the olfactory mucosa: a new test for the study of the
      hypothalamic functionality.

PMID- 4355996
TI  - A mechanism for stress-susceptibility in swine.

PMID- 4355997
TI  - A study of angiotensin II pressor response throughout primigravid pregnancy.
AB  - The present study was designed to ascertain sequentially the pressor response to
      angiotensin II in young primigravid patients throughout pregnancy in order a) to
      define when in pregnancy resistance to the pressor effects of angiotensin II
      develops; b) to define the physiologic sequence of events leading to this
      resistance; and c) to ascertain whether sensitivity to infused angiotensin II
      could be detected before the onset of clinical signs of pregnancy-induced
      hypertension. With this prospective approach, two separate groups of patients
      were defined. The first group of patients remained normal throughout pregnancy.
      The second group consisted of those patients who, while clinically normotensive
      during the initial phase of the study, ultimately developed hypertension of
      pregnancy.192 patients were studied; of these, 120 patients remained normotensive
      and 72 developed pregnancy-induced hypertension. In both groups, vascular
      resistance to infused angiotensin II (more than 8 ng/kg/min required to elicit a
      pressor response of 20 mm Hg in diastolic pressure) was demonstrated as early as
      the 10th wk of pregnancy. In the group that remained normotensive, maximum mean
      vascular resistance occurred at 18-30 wk of pregnancy, (mean pressor dose
      required being 13.5 to 14.9 ng/kg/min). In those subjects who developed pregnancy
      induced hypertension, the mean maximum dose required was 12.9 ng/kg/min, which
      was observed at the 18th wk of pregnancy. By the 22nd wk there was a clear
      separation of the two groups, with the mean dose requirement of the subjects
      destined to develop hypertension being progressively less than that of those who
      remained normal. The difference between the two groups became significant (P <
      0.01) by 23-26 wk of pregnancy. Among patients requiring more than 8 ng/kg/min on
      one or more tests done between wk 28-32, 91% remained normotensive. Conversely,
      during the same time period among patients requiring less than 8 ng/kg/min, on at
      least one occasion, 90% developed pregnancy-induced hypertension.

PMID- 4355998
TI  - Culture of human endothelial cells derived from umbilical veins. Identification
      by morphologic and immunologic criteria.
AB  - Endothelial cells were isolated from freshly obtained human umbilical cords by
      collagenase digestion of the interior of the umbilical vein. The cells were grown
      in tissue culture as a homogeneous population for periods up to 5 mo and some
      lines were subcultured for 10 serial passages. During the logarithmic phase of
      cell growth, cell-doubling time was 92 h. Light, phase contrast, and scanning
      electron microscopy demonstrated that cultured human endothelial cells grew as
      monolayers of closely opposed, polygonal large cells whereas both cultured human
      fibroblasts and human smooth muscle cells grew as overlapping layers of parallel
      arrays of slender, spindle-shaped cells. By transmission electron microscopy,
      cultured endothelial cells were seen to contain cytoplasmic inclusions (Weibel
      Palade bodies) characteristic of in situ endothelial cells. These inclusions were
      also found in endothelial cells lining umbilical veins but were not seen in
      smooth muscle cells or fibroblasts in culture or in situ. Cultured endothelial
      cells contained abundant quantities of smooth muscle actomyosin. Cultured
      endothelial cells also contained ABH antigens appropriate to the tissue donor's
      blood type; these antigens were not detectable on cultured smooth muscle cells or
      fibroblasts. These studies demonstrate that it is possible to culture
      morphologically and immunologically identifiable human endothelial cells for
      periods up to 5 mo.

PMID- 4355999
TI  - The metabolism of cholestanol, cholesterol, and bile acids in cerebrotendinous
      xanthomatosis.
AB  - The metabolism of cholesterol and its 5-dihydro derivative, cholestanol, was
      investigated by means of sterol balance and isotope kinetic techniques in 3
      subjects with cerebrotendinous xanthomatosis (CTX) and 11 other individuals. All
      subjects were hospitalized on a metabolic ward and were fed diets practically
      free of cholesterol and cholestanol. After the intravenous administration of [1,2
      (3)H]cholestanol, the radioactive sterol was transported and esterified in plasma
      lipoproteins in an identical manner to cholesterol. In these short-term
      experiments, the specific activity-time curves of plasma cholestanol conformed to
      two-pool models in both the CTX and control groups. However, cholestanol plasma
      concentrations, total body miscible pools, and daily synthesis rates were two to
      five times greater in the CTX than control individuals. The short-term specific
      activity decay curves of plasma [4-(14)C]cholesterol also conformed to two-pool
      models in both groups. However, in the CTX subjects the decay was more rapid, and
      daily cholesterol synthesis was nearly double that of the control subjects.
      Plasma concentrations and the sizes of the rapidly turning over pool of
      exchangeable cholesterol were apparently small in the CTX subjects, and these
      measurements did not correlate with the large cholesterol deposits found in
      tendon and tuberous xanthomas. Despite active cholesterol synthesis, bile acid
      formation was subnormal in the CTX subjects. However, bile acid sequestration was
      accompanied by a rise in plasma cholestanol levels and greatly augmented fecal
      cholestanol outputs. In contrast, the administration of clofibrate lowered plasma
      cholesterol levels 50% and presumably reduced synthesis in the CTX subjects.
      Plasma cholesterol concentrations and fecal steroid excretion did not change
      significantly during this therapy. These findings indicate that the excessive
      tissue deposits of cholesterol and cholestanol that characterize CTX were
      associated with hyperactive neutral sterol synthesis. The demonstration of
      subnormal bile acid formation suggests that defective bile acid synthesis may
      predispose to the neutral sterol abnormalities.

PMID- 4356001
TI  - Immune enhancement of pulmonary bactericidal activity in murine virus pneumonia.
AB  - Bacterial multiplication in the lung associated with murine Sendai virus
      pneumonia is caused by virus-induced defects in pulmonary bactericidal
      mechanisms. The nature of this effect has been studied in animals immunized
      against the challenge bacteria. Mice were immunized against Proteus mirabilis by
      intraperitoneal inoculation and by aerosol inhalation. After the development of
      immunity, mice were infected aerogenically with 10(4) TCID(50) of Sendai virus. 7
      days later, during the height of the bronchial inflammation and pulmonary
      consolidation, the mice were challenged with an aerosol of viable (35)S-labeled
      Proteus mirabilis or (32)P-labeled Staphylococcus aureus.Nonimmunized virus
      infected animals showed marked impairment of pulmonary bactericidal activity with
      subsequent multiplication of the bacterial strain in the case of Proteus
      mirabilis. Immunized nonvirus-infected animals showed enhancement of pulmonary
      bactericidal activity for the homologous and heterologous strains in comparison
      with nonimmunized animals. Virus-infected animals immunized by aerosol showed
      enhanced bactericidal activity against the homologous but not the heterologous
      bacterial strain. Neither virus infection nor immunization had a significant
      effect on the transport of particles in the lung. The data demonstrated that the
      bacterial multiplication associated with the virus pneumonia was prevented by
      preceding immunization against the homologous challenge organism. The data
      suggest a mechanism for controlling bacterial multiplication associated with
      virus pneumonias.

PMID- 4356000
TI  - In vivo suppression of the immune response to alloantigen by cholera enterotoxin.
AB  - The immune response of C57BL/6 mice to allogeneic (DBA/2) mastocytoma cell
      suspensions was profoundly suppressed by intraperitoneal administration of 1 mug
      cholera enterotoxin 4 days after antigenic stimulation. The immune response
      assayed 11 days after antigen showed decreased cytolytically active thymusderived
      (T) lymphocytes and markedly depressed serumagglutinating titers. A comparable
      suppression of the immune response to skin allografts (DBA/2-->C57BL/6) was also
      effected by cholera toxin administration, although there was no prolongation of
      allograft survival. The mechanism of the immune suppression is apparently related
      to the known adenylate cyclase stimulatory activities of choleragen.

PMID- 4356002
TI  - Lymph chylomicron formation during the inhibition of protein synthesis. Studies
      of chylomicron apoproteins.
AB  - The effect of impaired intestinal protein synthesis on chylomicron apoprotein
      composition was studied in mesenteric lymph fistula rats. Lymph was obtained from
      animals with impaired protein synthesis given intraperitoneal
      acetoxycycloheximide (ACH), a potent inhibitor of protein synthesis. Lymph
      chylomicrons were then isolated by ultracentrifugation and purified on agarose
      columns. Purified chylomicrons from control and ACH-treated animals were
      delipidated, and their apoprotein pattern was examined on sodium dodecyl sulfate
      (SDS) polyacrylamide gels. Because we had previously demonstrated a markedly
      increased lymph chylomicron size during the inhibition of protein synthesis, it
      was first necessary to determine whether chylomicron apoprotein composition
      normally varied with chylomicron size. Chylomicrons of varying sizes were
      prepared by differential ultracentrifugation, and their apoprotein composition
      was determined densitometrically on SDS polyacrylamide gels. No significant
      difference in apoprotein composition was found normally with varying chylomicron
      size. In contrast, however, chylomicrons from ACH-treated animals showed a 50%
      decrease in a major apoprotein band with R(1) 0.67. Other chylomicron apoproteins
      were not decreased as a result of impaired protein synthesis, suggesting
      differing rates of synthesis of the various chylomicron apoproteins. In vivo
      incorporation studies of [(3)H]leucine into the various apoproteins of lymph
      chylomicrons demonstrated that this apoprotein (R(1) 0.67) had the most rapid
      synthesis rate and suggested that it seemed most affected by impaired intestinal
      protein synthesis. Immunologic studies indicated that this apoprotein was
      immunologically related to high-density lipoproteins (HDL) and was present in
      chylomicrons isolated directly from small intestinal mucosa. These studies
      demonstrate that impaired intestimal protein synthesis is associated with a
      deficiency in one of the major chylomicron apoproteins and may in part explain
      the impaired lipid absorption seen during states of impaired protein synthesis.

PMID- 4356003
TI  - Alkaline phosphatase. Possible induction by cyclic AMP after cholera enterotoxin
      administration.
AB  - The present studies were undertaken to determine the role, if any, of cyclic
      3',5'-adenosine monophosphate (cyclic AMP) as a chemical inducer of rat liver
      alkaline phosphatase. Cholera enterotoxin, given intravenously to rats, led to a
      rapid rise in the activity of hepatic adenyl cyclase that was 7(1/2) times
      greater than control values in 6 h. Cyclic AMP levels were also significantly
      increased above control values while the activity of cyclic nucleotide
      phosphodiesterase was unchanged. Hepatic alkaline phosphatase activity was
      increased 5(1/2) times above control in 12 h, but its rise followed that of
      adenyl cyclase and cyclic AMP by several hours. Cycloheximide inhibited the rise
      of hepatic alkaline phosphatase but not that of adenyl cyclase. The
      administration of glucagon, a known stimulator of hepatic adenyl cyclase, and of
      dibutyryl cyclic AMP, led to similar striking increases in hepatic alkaline
      phosphatase activity. This alkaline phosphatase increase was blocked by the prior
      administration of cycloheximide. Bile duct ligation, a known stimulator of
      hepatic alkaline phosphatase activity, failed to produce any significant changes
      in adenyl cyclase or cyclic AMP. Concomitant treatment of rats with bile duct
      ligation and cholera enterotoxin or bile duct ligation and glucagon, had no
      additive effect on the increase in hepatic alkaline phosphatase activity,
      although the increase occurred earlier. These results suggest that: (a) cyclic
      AMP may act as an inducer of hepatic alkaline phosphatase: (b) the stimulation of
      hepatic alkaline phosphatase by cholera enterotoxin is mediated by cyclic AMP;
      (c) the rise in hepatic alkaline phosphatase following bile duct ligation is not
      mediated by cyclic AMP; (d) the same alkaline phosphatase in rat liver may be
      induced by two (or more) mechanisms, only one of which requires cyclic AMP.

PMID- 4356004
TI  - Prevention of gram-negative bacillary pneumonia using aerosol polymyxin as
      prophylaxis. I. Effect on the colonization pattern of the upper respiratory tract
      of seriously ill patients.
AB  - A prospective study used polymyxin B by aerosol to reduce colonization of the
      upper respiratory tract with nosocomial gram-negative bacilli. 58 high-risk
      patients from the Respiratory-Surgical Intensive Care Unit entered the trial. 33
      were randomly selected to receive 2.5 mg/kg/day of polymyxin B by hand atomizer
      into the pharynx, and tracheal tube if present. 17 of 25 control patients became
      colonized with gram-negative bacilli as compared with 7 of 33 polymyxin-treated
      patients (p < 0.01). Control patients became colonized with a total of 33 gram
      negative bacilli: 3 were Pseudomonas aeruginosa, 21 were species of
      Enterobacteriaceae. The polymyxin-treated patients became colonized with a total
      of 11 gram-negative bacilli: no P. aeruginosa and only 3 species of
      Enterobacteriaceae were recovered. Colonization increased with duration in
      Respiratory-Surgical Intensive Care Unit and with time of required controlled
      ventilation. Polymyxin most effectively prevented the increase in colonization in
      treated patients who stayed in the Respiratory-Surgical Intensive Care Unit for
      longer than 1 wk and who required controlled ventilation for at least 72 h.

PMID- 4356005
TI  - A study of the androgen receptors in a variety of androgen-sensitive tissues.

PMID- 4356006
TI  - Corticosterone metabolism by rat adrenocortical cell suspensions and monolayer
      cultures: the effect of damage on 11-dehydrogenase activity.

PMID- 4356007
TI  - The episodic nature of changes in ovine plasma cortisol levels and their response
      to adrenaline during adaptation to a new environment.

PMID- 4356009
TI  - Some properties of the hydro-osmotic vasopressin "effector": interactions with N
      ethylmaleimide.

PMID- 4356008
TI  - Properties of a simplified bioassay for adrenocorticotrophic activity using the
      steroidogenic response of isolated adrenal cells.

PMID- 4356010
TI  - Health services on economic development projects.

PMID- 4356011
TI  - Paradoxical blockade by p-chlorophenylalanine of 5-hydroxytryptophan facilitatory
      actions on spinal reflexes.

PMID- 4356012
TI  - Effects of phenoperidine on lamina V cells in the cat dorsal horn.

PMID- 4356013
TI  - Changes in spinal cord neural mechanisms associated with digitalis
      administration.

PMID- 4356014
TI  - Antiarrhythmic and electrophysiologic properties of UM-272, dimethyl quaternary
      propranolol, in the canine heart.

PMID- 4356015
TI  - Phenylephrine-induced increases in cardiac contractility, cyclic adenosine
      monophosphate and phosphorylase a.

PMID- 4356016
TI  - Effects of hycanthone on spermatogonial cells, deoxyribonucleic acid synthesis in
      bone marrow and dominant lethality in rats.

PMID- 4356017
TI  - Mutagenic action of hycanthone and IA-4 on yeast.

PMID- 4356018
TI  - Fine structure of rat uterine eosinophils and the possible role of eosinophils in
      the mechanism of estrogen action.

PMID- 4356019
TI  - Subcellular distribution and binding of (6,7-3H) estradiol in rat uterus, at
      equilibrium, after long-term intravenous infusion.

PMID- 4356020
TI  - Dynamic exchange of (6, 73H) estradiol-17beta at the subcellular level in rat
      uterus.

PMID- 4356021
TI  - Slowly exchangeable pool of estradiol in the rat uterus.

PMID- 4356022
TI  - Evaluation of micropore filter in the extracorporeal circulation.

PMID- 4356024
TI  - [Letter: Acute necrotizing encephalitis. Serological diagnosis in herpesvirus
      infection].

PMID- 4356023
TI  - [Editorial: Anatomical and physiopathological diagnosis of pituitary adenoma.
      Contribution of current anterior pituitary functions tests].

PMID- 4356025
TI  - Pulmonary phospholipids and surface properties of alveolar wash in experimental
      paraquat poisoning.

PMID- 4356026
TI  - Late effects of moderate doses of quartz dust on pulmonary function and tissue.
      An experimental study on rabbits.

PMID- 4356027
TI  - Late effects of large doses of quartz dust on pulmonary function and tissue. An
      experimental study on rabbits.

PMID- 4356028
TI  - Hepatitis A: detection by immune electron microscopy of a viruslike antigen
      associated with acute illness.
AB  - Spherical 27-nanometer particles were visualized in stools obtained from
      hepatitis A patients in the acute phase of the disease. The particle was
      serologically specific for this disease, and every hepatitis A patient tested
      demonstrated a serologic response to this antigen. The findings suggest that it
      is the etiologic agent of hepatitis A.

PMID- 4356029
TI  - Renin-angiotensin role in thirst: paradoxical enhancement of drinking by
      angiotensin converting enzyme inhibitor.
AB  - A competitive angiotensin converting enzyme antagonist SQ 20, 881 (SQ), was used
      to examine the role of the renin-angiotensin system in putative renin-dependent
      thirst in the albino rat. Significant enhancement of "renin-dependent" as well as
      renin-independent drinking was observed in the presence of peripheral SQ.
      Intraventricular SQ obviated this enhancement of drinking but did not affect the
      water intake caused by the original stimulus itself, whereas it sharply reduced
      drinking evoked by peripheral renin in nephrectomized rats. Prior renin depletion
      likewise had no influence on so-called renin-dependent thirst.

PMID- 4356030
TI  - Serological survey on infection with equine rhinopneumonitis virus among soliped
      animals in Iran.

PMID- 4356031
TI  - Ultrastructure of Leydig cell paracrystalline inclusions, possibly related to
      Reinke crystals, in the normal human testis.

PMID- 4356032
TI  - Ultrastructural investigation of the postnatal development of the hamster
      Harderian gland. II. Male and female.

PMID- 4356034
TI  - The structural organization of glomerular neuropile in the olfactory and
      accessory lobes of an Australian freshwater crayfish, Cherax destructor.

PMID- 4356033
TI  - Post-coital depletion of dense-core vesicles from the external layer of the
      rabbit median eminence.

PMID- 4356035
TI  - On the regeneration of the eye in Helix aspersa and Cryptomphallus aspersa.

PMID- 4356036
TI  - Cholinesterase in the posterior and intermediate lobes of the pituitary. Species
      differences as determined by light and electron microscopic histochemistry.

PMID- 4356037
TI  - Fine structure of eyespots in tornarian larvae (phylum: Hemichordata).

PMID- 4356038
TI  - Pinocytotic activity of the uterus of the rat.

PMID- 4356039
TI  - Electron microscopic studies of human pituitary tumors. II. Acidophilic adenomas.

PMID- 4356040
TI  - Kinetics of viral adsorption in singly and multiply infected bovine cells.

PMID- 4356042
TI  - [Amino constituents of tubal secretions in the rabbit. Zymogram--proteins--free
      amino acids].

PMID- 4356041
TI  - Field experiments with formalin-killed-virus vaccine against infectious bovine
      rhinotracheitis, bovine viral diarrhea and parainfluenza-3.

PMID- 4356044
TI  - Foreign cell acantholysis. Electron microscopic study on the pathodynamics of
      exocytosis.

PMID- 4356043
TI  - Distal and proximal sensory responses during stereotactic spinal tractotomy in
      man.

PMID- 4356045
TI  - Ultrastructure of signet ring cells in cutaneous metastases of gastric carcinoma.

PMID- 4356046
TI  - Effects of local anesthetics on glucose-stimulated insulin secretion from rat
      pancreas in vitro.

PMID- 4356048
TI  - Nature of the transport ATPase-digitalis complex. VI. Purification of and ouabain
      binding to a highly active cardiac Na+, K+-ATPase.

PMID- 4356047
TI  - Studies relating to the antihypertensive and antidysrhythmic action of indoramin.

PMID- 4356049
TI  - Two-dimensional polyacrylamide gel electrophoresis of chromatin proteins of
      normal rat liver and Novikoff hepatoma ascites cells.

PMID- 4356050
TI  - Isolation of tissue collagenase from homogenates of embryonic chick bones.

PMID- 4356051
TI  - Evidence for the presence of 3', 5'-cyclic AMP in plant tissues.

PMID- 4356052
TI  - Proline biosynthesis: multiple defects in Chinese hamster ovary cells.

PMID- 4356053
TI  - Effect of concanavalin A on cellular slime mold development: premature appearance
      of membrane-bound cyclic AMP phosphodiesterase.

PMID- 4356054
TI  - Vasoactive intestinal polypeptide and glucagon: stimulation of adenylate cyclase
      activity via distinct receptors in liver and fat cell membranes.

PMID- 4356055
TI  - Effect of concanavalin A on interferon induction by poly IC.

PMID- 4356056
TI  - Analogs of adenosine 3',5'-cyclic phosphate. II. Synthesis and enzymatic activity
      of derivatives of 1,N6-ethenoadenosine 3',5'-cyclic phosphate.

PMID- 4356057
TI  - Effects of protein-modifying reagents on an isoenzyme of potato apyrase.
AB  - Treatment of an isoenzyme of potato apyrase of high adenosine
      triphosphatase/adenosine diphosphatase (ATPase/ADPase) ratio with iodine, N
      acetylimidazole or tetranitromethane inactivates the ATPase activity of this
      enzyme faster than its ADPase activity. There was protection by substrates with
      the two last-named substances. This and the appearance of nitrotyrosine suggests
      the participation of tyrosyl residues in both enzymic activities of potato
      apyrase. The participation of thiol groups is excluded by the insensitivity of
      apyrase to p-chloromercuribenzoate. Also, 2-hydroxy-5-nitrobenzyl bromide or
      carboxymethylation produce the same rate of inactivation of ATPase and ADPase
      activities. Substrates protect both activities from inactivation. Hydrogen
      peroxide and photo-oxidation inactivate ATPase activity faster than ADPase
      activity. There is no protection by substrates. Analysis of pH effects on V(max.)
      and K(m) suggest different pK values for the amino acid residues at the ATP and
      ADP sites.

PMID- 4356059
TI  - Lipids of Crithidia fasciculata. The occurrence and turnover of
      phosphoinositides.

PMID- 4356058
TI  - Direct measurement of proton binding to the active ternary complex of pig heart
      lactate dehydrogenase.
AB  - With the use of a glass electrode it is shown that one proton is taken up from
      the solvent when o-nitrophenylpyruvate forms a ternary complex with lactate
      dehydrogenase and NADH at pH8 and before the complex has rearranged to give
      products.

PMID- 4356061
TI  - Detailed structure of sphingomyelins and ceramides from different regions of
      bovine kidney with special reference to long-chain bases.

PMID- 4356060
TI  - The sphingolipid composition of bovine kidney cortex, medulla and papilla.

PMID- 4356062
TI  - Microbiological optical resolution of a racemic synthetic prostaglandin
      intermediate.

PMID- 4356063
TI  - Effects of antilipolytic agents and alpha-adrenergic antagonists on cyclic AMP
      metabolism in hamster white adipocytes.

PMID- 4356064
TI  - Sialography: past, present, and future.

PMID- 4356065
TI  - Selective inhibition of human distal tubular function by demeclocycline.

PMID- 4356066
TI  - [Viruses and interferon as possible regulators of repair activity in cells of
      higher organisms].

PMID- 4356067
TI  - [Formation of chromosome anomalies, induced by poliovirus RNA, in cells with
      active and defective repair systems].

PMID- 4356068
TI  - [Study of photophosphorylation by the electron paramagnetic resonance method].

PMID- 4356069
TI  - Anti-shock action of steroids other than cortisone.

PMID- 4356070
TI  - Effect of biliary tract obstruction on liver microsomes in the rat.

PMID- 4356071
TI  - Role of immunity in viral-induced bacterial superinfections of the lung.
AB  - Although viral illnesses are predisposing causes for pulmonary bacterial
      infections, the interrelationships of viral virulence and host immunity to
      alterations in susceptibility to bacterial infection are incompletely understood.
      We used two mutant strains of encephalomyocarditis virus (minimally virulent
      Mengo-37A and a highly virulent Columbia SK [Col-SK]) to investigate these
      interrelationships. Mice that had been immunized to Mengo-37A, and nonimmunized
      controls, were challenged with aerosols containing 10(4) plaque-forming units of
      Mengo-37A or Col-SK per liter. The effect of each viral infection on pulmonary
      antibacterial activity was assessed 3 days later by measuring the capacity of the
      lungs to kill inhaled radiophosphorus ((32)P)-labeled Staphylococcus aureus. The
      degree of antibacterial dysfunction found was proportional to the virulence of
      the infecting virus. If the host was immune to the infecting virus, bactericidal
      function was not impaired by viral challenge. Neither mutant caused significant
      pulmonary damage; therefore: (i) viral-induced impairment in bactericidal
      activity reflects, quantitatively, the virulence of the virus and (ii) viral
      immunity protects pulmonary bacterial defenses by preventing damage to the
      phagocyte from the virus or its attendant metabolic abnormalities.

PMID- 4356072
TI  - Synergistic effect in viral-bacterial infection: combined infection of the murine
      respiratory tract with Sendai virus and Pasteurella pneumotropica.
AB  - Synergism was demonstrated between Sendai virus and Pasteurella pneumotropica in
      the respiratory tract of mice showing no evidence of previous infection with
      either agent. Mice aerosol challenged with P. pneumotropica invariably eliminated
      the viable organism from their lungs within 72 h. In contrast, intrapulmonary
      killing was delayed in animals previously infected with Sendai virus. Maximum
      synergism was observed when virus infection preceded bacterial challenge by 6
      days. At this time, a mortality rate of 37% was observed as compared with 0, 10,
      20, and 10%, respectively, in those animals in which the virus infection preceded
      bacterial challenge by 1, 3, 9, and 12 days. Previous immunization with Sendai
      virus completely prevented virus infection and thus the synergistic effect.
      Synergism with endogenous flora was also noted. Six days after virus infection an
      endogenous Pasteurella sp. began to proliferate in the bronchopulmonary tissues.
      Up to 10(4) colony-forming units per lung were recovered but no animals died of
      the endogenous Pasteurella infection.

PMID- 4356073
TI  - Mycoplasma-associated induction of interferon in ovine leukocytes.
AB  - A mycoplasmal species, Acholeplasma laidlawii, isolated as a contaminant from a
      fetal lamb kidney cell line, was shown to be associated with the induction of
      interferon in cultures of ovine peripheral blood leukocytes. Broth cultures of
      the mycoplasma induced between 20 and 230 U of interferon per ml in leukocytes
      from two adult ewes. The amount of interferon produced correlated with the
      inoculum size of mycoplasma. Interferon production was associated with
      replication of the mycoplasma in the leukocyte cultures. Interferon was not
      induced by sterile mycoplasmal broth, a cell-free filtrate of the mycoplasmal
      cultures, or heat-inactivated mycoplasmas. The antiviral substance was
      characterized as interferon by the usual criteria.

PMID- 4356075
TI  - Ultrastructure of the intermediate stages in the reverting L-phase organisms of
      Staphylococcus aureus and Streptococcus faecalis.

PMID- 4356074
TI  - Functional development of the hypothalamo-hypophyseal-adrenal cortex axis in the
      chick embryo, Gallus domesticus.

PMID- 4356076
TI  - Studies on lysosomal acid phosphatase in virus infected HEp-2 cells.

PMID- 4356078
TI  - Changes in myelin following trauma of the spinal cord in monkeys.

PMID- 4356077
TI  - In vitro uptake of active nerve growth factor by dorsal root ganglia of embryonic
      chick.

PMID- 4356079
TI  - Elaidic acid and serum lipoproteins in starved and fed rats.

PMID- 4356080
TI  - Phosphatase systems in Fasciolopsis buski Lankester, 1857 and Gastrodiscus
      aegyptiacus cobbold, 1876.

PMID- 4356081
TI  - The effect of parathyroid hormone on rabbit renal cortex adenyl cyclase during
      development.

PMID- 4356082
TI  - Vitamin D-dependency rickets in institutionalized, mentally retarded children on
      long term anticonvulsant therapy. II. The response to 25-hydroxycholecalciferol
      and to vitamin D2.

PMID- 4356083
TI  - Effects of angiotensin on the central nervous system.

PMID- 4356084
TI  - [State of peripheral endocrine glands 6 months after hypophysectomy, and their
      sensitivity to trophic hormones of the hypophysis].

PMID- 4356085
TI  - [Effect of ACTH on some aspects of cholesterol and cholesterol ester metabolism
      in the rat's adrenal glands].

PMID- 4356086
TI  - Phospholipids of outer mitochondrial membranes. Effect of ascorbate on their
      polyunsaturated fatty acids.

PMID- 4356087
TI  - Endospores of actinomycetes: dormancy and germination.

PMID- 4356089
TI  - Accelerated auto-infection with Strongyloides species complicating terminal
      carcinomatosis.

PMID- 4356090
TI  - Sclerosing capillary hemangioma in a rhesus monkey.

PMID- 4356088
TI  - A parasitological survey in the Jogjakarta area of Central Java, Indonesia.

PMID- 4356091
TI  - The metabolism of crotyl phosphate, crotyl alcohol and crotonaldehyde.

PMID- 4356092
TI  - [Recognising premalignant changes in the larynx (author's transl)].

PMID- 4356093
TI  - Carcinoid-islet cell tumors.

PMID- 4356094
TI  - Pseudotumour cerebri in Africans.

PMID- 4356095
TI  - [Meningiomas in the Ivory Coast].

PMID- 4356096
TI  - ["Gliomas" (neuroectodermal tumors) in Senegal].

PMID- 4356097
TI  - Some aspects of ion movements across the membrane of mitochondria isolated from
      normal and tumour tissues.

PMID- 4356098
TI  - Insulin and ACTH production by a streptozotocin responsive islet cell carcinoma.

PMID- 4356099
TI  - Effects of streptozotocin on an islet cell carcinoma with hypercalcemia.

PMID- 4356100
TI  - Endocrine studies in an arrhenoblastoma responsive to dexamethasone, ACTH and
      human chorionic gonadotropin.

PMID- 4356101
TI  - Systemic lupus erythematosus with adrenal insufficiency.

PMID- 4356103
TI  - One (of)alpha-1-lipoprotein in acute viral hepatitis.

PMID- 4356102
TI  - Bartter's syndrome and erythrocytosis.

PMID- 4356104
TI  - [Metabolism of plasma lipoproteins].

PMID- 4356105
TI  - [Influence of in vivo irradiation on plasma lipoproteins in the rabbit].

PMID- 4356106
TI  - [Possible relationship between hepatic steatosis caused by alpha-amanitine and
      lipoprotein metabolism in the rat].

PMID- 4356107
TI  - Study on pre-beta1 lipoprotein fraction.

PMID- 4356108
TI  - [Lipoprotein metabolism].

PMID- 4356109
TI  - The role of lecithin: cholesterol acyltransferase in the metabolism of plasma
      lipoproteins.

PMID- 4356110
TI  - [Neonatal hyperlipemia due to lipoprotein lipase deficiency].

PMID- 4356111
TI  - Prevalence of lipoprotein abnormalities in patients with peripheral vascular
      disease.

PMID- 4356112
TI  - [Changes in blood lipoproteins during the initial phase of fat embolism.
      Preliminary study].

PMID- 4356113
TI  - [General comments on the structure of normal lipoproteins].

PMID- 4356114
TI  - [Structure of the beta-lipoprotein, used with digitonin and streptolysin as
      specific markers of free cholesterol].

PMID- 4356115
TI  - [Heterogeneity of apolipoprotein A1 of the HDL of human serum].

PMID- 4356116
TI  - [Structure of normal and pathologic lipoproteins].

PMID- 4356117
TI  - Biochemical and clinical aspects of various lipoprotein patterns.

PMID- 4356118
TI  - [Differential diagnosis of hyperlipoproteinemia using simultaneous determination
      of the lipids of the beta-prebeta lipoprotein group and of the lipid (beta and
      pre-beta)-cholesterol ratio].

PMID- 4356119
TI  - [Characterization of pre-beta hyperlipoproteinemias using 3 methods of
      electrophoresis].

PMID- 4356120
TI  - [Properties of heavy (Sf 4-6) carbamylated human betalipoproteins].

PMID- 4356121
TI  - Aspartylglycosaminuria (AGU). Further aspects on its clinical picture, mode of
      inheritance and epidemiology based on a series of 57 patients.

PMID- 4356122
TI  - Biochemical diagnosis of aspartylglycosaminuria.

PMID- 4356123
TI  - Isolation of a murine hepatitis virus from Swiss mice treated with antilymphocyte
      serum.

PMID- 4356124
TI  - The influence of mycoplasmas on the cytopathic effect of varicella virus.

PMID- 4356125
TI  - The electron-transport system of mitochondria from the slime mould Physarum
      polycephalum.
AB  - A method is described for the preparation of mitochondria from the slime mould
      Physarum polycephalum; the mitochondria were not coupled. P. polycephalum
      mitochondria oxidized added NADH via a rotenone-insensitive pathway, but the
      oxidation of malate plus glutamate was rotenone sensitive; both of these
      substrates reduced much less cytochrome b than did succinate, in both aerobic and
      anaerobic steady states. Spectroscopy at 77 degrees K separated three absorption
      maxima in the alpha-band region, at 560nm, 553nm and one at 547nm due to
      cytochrome c. The absorption at 553nm was increased in the aerobic steady state
      by the addition of 2-heptyl-4-hydroxyquinoline N-oxide, suggesting that it was
      due to a b-type cytochrome. All three absorption maxima appeared in the aerobic
      steady state after the addition of a range of substrates. The respiratory
      activity with different substrates and the response to inhibitors of respiration
      were similar to those previously described for fungus mitochondria (Weiss et al.,
      1970; Erickson & Ashworth, 1969). When grown under conditions of haem limitation
      the mitochondria contained a lower concentration of cytochromes than normal.

PMID- 4356126
TI  - Polyprenyl pyrophosphate-p-hydroxybenzoate polyprenyltransferase activity in
      mitochondria of broad-bean seeds and yeast.
AB  - Cell-free homogenates prepared from broad-bean seeds and yeast cells are capable
      of synthesizing 4-carboxy-2-polyprenylphenols from p-hydroxybenzoate and either
      isopentenyl pyrophosphate or protein-bound polyprenyl pyrophosphates (produced by
      incubating a Micrococcus lysodeikticus extract with isopentenyl pyrophosphate).
      The mitochondria contained all the polyprenyl pyrophosphate-p-hydroxybenzoate
      polyprenyltransferase activity; however, unlike the homogenates they could not
      synthesize a side chain from isopentenyl pyrophosphate and had to be provided
      with protein-bound polyprenyl pyrophosphates.

PMID- 4356127
TI  - Hormone-sensitive adenylyl cyclases. Useful models for studying hormone receptor
      functions in cell-free systems.

PMID- 4356128
TI  - [Regulation of the production and utilization of monophosphate nucleosides during
      the growth cycle in B. subtilis].

PMID- 4356129
TI  - [Preliminary experimental morphologic and electron microscopic studies of the
      connection between acupuncture points on the limb and segments of the spinal
      cord].

PMID- 4356130
TI  - The detection of carcinoembryonic antigen in whole serum from patients with
      malignant and nonmalignant disease.

PMID- 4356131
TI  - Alcohol inhibition of cyclic AMP-induced insulin release.

PMID- 4356133
TI  - A post-training survey of community psychiatrists.

PMID- 4356132
TI  - [Adenosine cyclic monophosphate (cycl AMP) and enzymatic secretion of the
      pancreas].

PMID- 4356134
TI  - Community liaison with a mental hospital.

PMID- 4356136
TI  - Control of plasma aldosterone in primary aldosteronism: distinction between
      adenoma and hyperplasia.

PMID- 4356135
TI  - Growth hormone studies before and during catch-up growth in a child with
      emotional deprivation and short stature.

PMID- 4356137
TI  - Urinary cyclic 3',5'-adenosine monophosphate levels in diabetes mellitus before
      and after treatment.

PMID- 4356138
TI  - Synthesis and biological activity of certain carbamoyl and alkoxycarbonyl
      derivatives of adenosine 3',5'-cyclic phosphate.

PMID- 4356140
TI  - Solid-phase synthesis of (3-proline,8-isoleucine)-,(1-sarcosine,3-proline,8
      isoleucine)-, and (4-phenylalanine,8-isoleucine)angiotensin II as the antagonists
      of the parent hormone.

PMID- 4356139
TI  - Pancuronium bromide and other steroidal neuromuscular blocking agents containing
      acetylcholine fragments.

PMID- 4356141
TI  - Reconstitution of cytochrome oxidase vesicles and conferral of sensitivity to
      energy transfer inhibitors.

PMID- 4356142
TI  - Intercellular communication and tissue growth. VI. Failure of exchange of
      endogeneous molecules between cancer cells with defective junctions and
      noncancerous cells.

PMID- 4356144
TI  - Studies on the epidemiology, microbiology and immunology of trachoma among
      children at three centres in Western Australia.

PMID- 4356143
TI  - Molecular sieving of red cell membranes during gradual osmotic hemolysis.

PMID- 4356145
TI  - Familial combined hyperlipoproteinemia: studies in 91 adults and 95 children from
      33 kindreds.

PMID- 4356146
TI  - Cortisol metabolism in glucose-6-phosphate dehydrogenase deficiency.

PMID- 4356148
TI  - Herpes simplex meningitis: isolation of herpes simplex virus type 2 from
      cerebrospinal fluid.

PMID- 4356147
TI  - Etiology of progressive multifocal leukoencephalopathy. Identification of
      papovavirus.

PMID- 4356149
TI  - Case records of the Massachusetts General Hospital. Weekly clinicopathological
      exercises. Case 50-1973.

PMID- 4356151
TI  - Possible involvement of taurine in the genesis of muscular dystrophy.

PMID- 4356150
TI  - Cyclic GMP and cell movement.

PMID- 4356152
TI  - Salting-out in amphiphilic gels as a new approach to hydrophobic adsorption.

PMID- 4356153
TI  - The fluorescence of quinacrine mustard with nucleic acids.

PMID- 4356155
TI  - Intake and excretion patterns of naturally occurring radium-226 in humans.

PMID- 4356154
TI  - Depression of substrate inhibition in gamma irradiated lactic dehydrogenase.

PMID- 4356156
TI  - [Leiomyoma of the esophagus with mediastinal symptoms].

PMID- 4356157
TI  - [Aspect of mega-esophagus overlying gastric linitis].

PMID- 4356158
TI  - [Hiatal hernia and ulcer of the neck of the hernial sac: an unusual case].

PMID- 4356159
TI  - [Polypous polyadenomas of the stomach and Menetrier's mucous adenomatosis].

PMID- 4356160
TI  - [Ulcer-like cancer of the stomach].

PMID- 4356161
TI  - [Double cancer of the stomach at onset].

PMID- 4356162
TI  - [Cancer of the 3d portion of the duodenum with pancreatic point of origin].

PMID- 4356164
TI  - [Tumor of the right iliac fossa caused by appendicular mucocele].

PMID- 4356163
TI  - [Volvulus of the small intestine in perforated Meckel's diverticulum].

PMID- 4356165
TI  - [Case of diffuse colonic Crohn's disease in a young girl].

PMID- 4356166
TI  - [Pelvic appendicitis compressing the rectum].

PMID- 4356167
TI  - [Voluminous cecal ectasia caused by cancer of the right angle of the colon].

PMID- 4356168
TI  - [Enterocyst of the rectum].

PMID- 4356169
TI  - [Microlithiasis of the gallbladder and defective postgastrectomy function or
      "lark-mirror" gallbladder].

PMID- 4356170
TI  - [Invagination of the common bile duct, Wirsung's duct, Vater's ampulla and the
      duodenum caused by an ampullar tumor].

PMID- 4356171
TI  - [Voluminous cavernous angioma of the right lobe of the liver].

PMID- 4356172
TI  - [Giant hemangioma of the liver. Value of scintiscanning, using erythrocytes
      labeled with Tc99m].

PMID- 4356174
TI  - [Fibro-thecoma of the ovary with pleural effusion and ascites].

PMID- 4356173
TI  - [Calcifying pancreatitis and false cyst of the pancreas].

PMID- 4356175
TI  - [Hereditary sacro-coccygeal agenesis with incomplete anal perforation. Mega
      rectum in childhood. Pelvic meningocele in adulthood].

PMID- 4356176
TI  - [Cystic lymphangioma of the mesentery].

PMID- 4356177
TI  - Proteolytic degradation of polymyxins by the enzymes of Bacillus polymyxa.

PMID- 4356178
TI  - [A benign mesenchymal tumor (angiofibroma) of the liver with hypoglycaemia
      (author's transl)].

PMID- 4356179
TI  - The chemistry of porphyrin pi-cations.

PMID- 4356180
TI  - Polarized single crystal absorption spectra of carboxy- and oxyhemoglobin.

PMID- 4356182
TI  - Electron paramagnetic resonance studies of iron porphin and chlorin systems.

PMID- 4356181
TI  - The molecular structure of porphyrin complexes in solution: the interaction of
      metal porphyrins with various steroids.

PMID- 4356183
TI  - ESR studies of porphyrin pi-cations: the 2A1u and 2A2u states.

PMID- 4356184
TI  - Metal-metal interactions involving porphyrins: iron-iron spin exchange and iron
      chromium electron transfer.

PMID- 4356185
TI  - Oxidation of ferric porphyrins.

PMID- 4356186
TI  - Chemistry of type c heme-peptide systems.

PMID- 4356187
TI  - The study of Zn porphin in an n-octane crystal by optical spectroscopy and
      magnetic resonance.

PMID- 4356188
TI  - Proceedings: Linear and skeletal growth in congenital adrenal hyperplasia.

PMID- 4356189
TI  - 1,6-Di-O-methanesulphonyl-2,3-4,5-dianhydro-L-iditol, a new potential antitumour
      agent. Biological investigations.

PMID- 4356192
TI  - [Determination of sedimentation coefficients by the radioactivity partition
      method. Application to trace proteins].

PMID- 4356193
TI  - [Influence of thyroidectomy on the enzyme activities of hepatic mitochondria in
      rats].

PMID- 4356194
TI  - The Cell.

PMID- 4356195
TI  - Entamoeba histolytica.

PMID- 4356196
TI  - The prevalence of entamoeba histolytica cyst-passers among hospital inpatients at
      Princess Tsehai Memorial Hospital.

PMID- 4356197
TI  - Gas chromatographic determination of vitamin D in cod liver oil, pharmaceuticals
      and veterinary preparations.

PMID- 4356198
TI  - Inhibition of pyridoxal kinase from rat liver in vitro by aromatic and aliphatic
      amines.

PMID- 4356199
TI  - Aggregation of Hodgkin's disease.

PMID- 4356200
TI  - Depression in the young.

PMID- 4356201
TI  - Intraosseous malignant mixed tumor of the maxilla: review of the literature and
      report of case.

PMID- 4356202
TI  - [Abdominal neoplasms in childhood].

PMID- 4356203
TI  - Increased production of cyclic AMP in gastric tissue by stimulation of histamine2
      (H2)-receptors.

PMID- 4356204
TI  - Inhibitory effect of gammahydroxybutyric acid and gammaaminobutyric acid on the
      dopamine cells in the substantia nigra.

PMID- 4356205
TI  - Release of prostaglandins from isolated cat spleen by angiotensin and
      vasopressin.

PMID- 4356206
TI  - The work of the primary liver cancer research project: the differential diagnosis
      of primary malignant hepatoma in patients referred to the liver cancer unit.

PMID- 4356207
TI  - Relationship of rapid eye movement density to the prior accumulation of sleep and
      wakefulness.

PMID- 4356208
TI  - Psychophysiology. Computer software.

PMID- 4356209
TI  - Failure of reserpinization to decrease the positive inotropic effect of dibutyryl
      cyclic AMP.

PMID- 4356210
TI  - Dibutyryl cyclic AMP--an effective antidote against lethal amounts of amobarbital
      in the rat.

PMID- 4356211
TI  - The effects of dibutyryl cyclic AMP on the hepatic mixed function oxidase system
      in hormonally altered rats.

PMID- 4356212
TI  - Comparative studies on lipid composition of Zea mays L. and Typha latifolia L.
      pollens.

PMID- 4356213
TI  - Adrenergic supersensitivity during ethanol withdrawal in the rat.

PMID- 4356214
TI  - Interferon induction and suppression of solid tumor growth in rats by tilorone
      hydrochloride.

PMID- 4356215
TI  - Experimental challenge of beef calves vaccinated intranasally with bovine
      myxovirus parainfluenza-3 vaccine.

PMID- 4356216
TI  - [Cirrhosis of the liver and small intestine. Clinical, biological, histological,
      immunological and bacteriological comparisons].

PMID- 4356217
TI  - [Immunological reactions during drug-induced gastritis].

PMID- 4356218
TI  - [The place of radiological exploration in the diagnosis of hydatid cysts of the
      liver].

PMID- 4356219
TI  - [The occipito-atloid functional mass].

PMID- 4356220
TI  - [New method of phlebography: extended carboxyangiography for exploration of the
      venous system and especially for study of the supra-hepatic veins].

PMID- 4356221
TI  - [Hormonal (vasopressin-corticoid) treatment of 16 cases of inoperable cerebral
      tumors with little or no malignant potential].

PMID- 4356222
TI  - [Study of the qualitative cytology and prognosis of chronic lymphoid leukemia
      with cutaneous manifestations].

PMID- 4356223
TI  - [Temporal arteritis and dissecting hematoma of the aorta].

PMID- 4356224
TI  - Hormaonal regulation of cyclic AMP.

PMID- 4356225
TI  - [Ossification times for human extremities].

PMID- 4356227
TI  - Cryosurgery and glomus jugulare tumors of the ear.

PMID- 4356226
TI  - [Sudden death in pulmonary adenomatosis with silent metastases into the brain].

PMID- 4356228
TI  - Primary intracranial germ cell tumours.

PMID- 4356229
TI  - Metastases and recurrences in nephroblastoma.

PMID- 4356230
TI  - Radiation necrosis of the humerus. A report of three cases.

PMID- 4356231
TI  - Physical and chemical properties of respirable coal dust from two United States
      mines.

PMID- 4356233
TI  - Pearly penile papules. Acral angiofibromas.

PMID- 4356232
TI  - The determination of quartz in airborne respirable granite dust by infrared
      spectrophotometry.

PMID- 4356234
TI  - Vincristine neurotoxicity and abnormal secretion of antidiuretic hormone.

PMID- 4356235
TI  - [In vitro study of the relationship between Entamoeba histolytica and Candida
      albicans. I. Aspects of phagocytosis of C. albicans by E. histolytica.
      (Preliminary note)].

PMID- 4356236
TI  - The modified stuart medium. A common transport medium for Entamoeba histolytica
      and enteric bacteria. (Preliminary report).

PMID- 4356237
TI  - Different optimal temperatures for the biologic activity of rabbit and human
      lymphocytes in vitro.

PMID- 4356238
TI  - Threonine-sensitive aspartokinase from Escherichia coli. Magnetic resonance and
      binding studies.

PMID- 4356240
TI  - Biosynthesis of the C18 family of cutin acids: omega-hydroxyoleic acid, omega
      hydroxy-9,10-epoxystearic acid, 9,10,18-trihydroxystearic acid, and their delta12
      unsaturated analogs.

PMID- 4356239
TI  - Amino protons of cytosine. Chemical exchange, rotational exchange, and salt
      induced proton magnetic resonance chemical shifts of aqueous 2',3'-cyclic
      cytidine monophosphate.

PMID- 4356241
TI  - Organization of the lipid phase in viral membranes. Effects of independent
      variation of the lipid and the protein composition.

PMID- 4356242
TI  - Location of aromatic amino acid residues in bovine serum high-density
      lipoprotein.

PMID- 4356243
TI  - Lipid requirements for Rhodopsin regenerability.

PMID- 4356244
TI  - The enzymic phosphorylation of N6-(delta 2-isopentenyl) adenosine in chick liver
      homogenates.

PMID- 4356245
TI  - Comparative study of molecular species of glycerolipids in sarcotubular membranes
      of skeletal muscle of rabbit, rat, chicken, and man.

PMID- 4356247
TI  - Properties of inosinic acid dehydrogenase from Bacillus subtilis. II. Kinetic
      properties.

PMID- 4356246
TI  - Properties of inosinic acid dehydrogenase from Bacillus subtilis. I. Purification
      and physical properties.

PMID- 4356248
TI  - The effect of oxygen on metabolism in Astasia.

PMID- 4356249
TI  - The reaction of N-ethylmaleimide with different forms of cytochrome oxidase.

PMID- 4356250
TI  - Alpha-aminobutyronitrile as an intermediate in cyanide fixation by Rhizoctonia
      solani.

PMID- 4356251
TI  - Diagnosis of Pneumocystis carinii pneumonia by transbronchoscopic lung biopsy.

PMID- 4356253
TI  - The hypothalamic areas involved in the control of mammotrophic and lactotrophic
      processes in sheep.

PMID- 4356252
TI  - Separation of some pituitary proteohormones by disc-electrophoresis.

PMID- 4356254
TI  - Glucocorticoid receptors in pituitary tumor cells. I. Cytosol receptors.

PMID- 4356255
TI  - The serum high density lipoproteins of Macacus rhesus. I. Isolation, composition,
      and properties.

PMID- 4356256
TI  - The serum high density lipoproteins of Macacus rhesus. II. Isolation,
      purification, and characterization of their two major polypeptides.

PMID- 4356257
TI  - Nuclear magnetic resonance studies on pyridine dinucleotides. I. The pH
      dependence of the carbon 13 nuclear magnetic resonance of nicotinamide adenine
      dinucleotide.

PMID- 4356258
TI  - Structural bases for function in cytochromes c. An interpretation of comparative
      x-ray and biochemical data.

PMID- 4356259
TI  - Gluconeogenesis in isolated hepatic parenchymal cells.

PMID- 4356260
TI  - The amino acid sequence of ovine pancreatic ribonuclease A.

PMID- 4356261
TI  - Adrenal mitochondrial cytochrome P-450 and cholesterol side chain cleavage
      activity. Differences in the response of the zona glomerulosa and zona
      fasciculata-reticularis to adrenocorticotropic hormone and its withdrawal.

PMID- 4356262
TI  - Evidence against the natural occurrence of alpha-nicotinamide adenine
      dinucleotide in Azotobacter vinelandii.

PMID- 4356263
TI  - Ferredoxins from Bacillus polymyxa. Low potential iron-sulfur proteins which
      appear to contain single four iron, four sulfur centers accepting a single
      electron on reduction.

PMID- 4356264
TI  - Quantitative relations of fetal and maternal pitiutary-adrenal systems.
AB  - Even though certain aspects of the fetal pituitary-adrenal system have been
      extensively studied, much remains to be learned of its basic development and
      function. In the present work, the effect of maternal hypophysectomy upon
      quantitative pituitary-adrenal relations in mother and fetus was investigated in
      pregnant beagle dogs. At 57 days gestation in each of seven normal animals and
      seven animals 3 wk posthypophysectomy, a cannula for collection of adrenal
      effluent was placed in a single fetus in utero under halothane anesthesia. A
      timed fetal adrenal sample was obtained; ACTH (10 mU) was injected into the
      fetus; 3 min thereafter a second fetal adrenal sample was collected and fetal and
      maternal peripheral arterial samples were drawn. All fetuses and their adrenal
      glands were weighed. Concentrations of cortisol and corticosterone were
      determined by a modification of the double-isotope dilution derivative method of
      Kliman and Peterson. Mean peripheral cortisol concentrations in mother and fetus
      were 92 and 94 ng/ml, respectively (ratio 1.0), in normal pregnancies and 11 and
      54 ng/ml, respectively (ratio 0.2), in maternal hypophysectomy pregnancies.
      Weights of fetal adrenal gland pairs of 32 and 44 mg, respectively, in normal and
      hypophysectomy pregnancies indicate increased fetal ACTH secretion in response to
      lowered circulating cortisol in the fetus secondary to maternal hypophysectomy.
      These data demonstrate the presence of an active pituitary-adrenal feedback
      mechanism in the dog fetus which is partly influenced by maternal pituitary
      adrenal function. The shift in the maternal-fetal ratio of peripheral cortisol
      concentrations from 1.0 to 0.2 occasioned by maternal hypophysectomy neither
      supports nor rules out the presence of specific placental mechanisms affecting
      relative concentrations of cortisol in mother and fetus. It does suggest,
      however, that the relative steroid input into maternal and fetal compartments is
      one of the factors which influences such concentration ratios. Concentrations of
      cortisol were significantly higher in fetal adrenal effluent (pre-ACTH) than in
      fetal peripheral plasma in normal pregnancies, which demonstrates secretion of
      cortisol by the fetus and shows that corticosteroid of maternal origin does not
      lead to complete suppression of fetal pituitary-adrenal function. Cortisol
      secretion rates in response to exogenous ACTH were essentially the same in
      fetuses in normal and hypophysectomy pregnancies (132 and 128 ng/min,
      respectively). Thus, fetal adrenal responsiveness to ACTH, i.e., maximum
      secretory capacity, is not enhanced by increased ACTH stimulation sufficient to
      induce adrenal hypertrophy in the same fetuses.

PMID- 4356265
TI  - Prognostic typing in breast cancer. Further investigation of a necropsy series
      compared with recent surgical specimens.
AB  - A comparison of material from necropsy and surgical series has shown that breast
      carcinoma of cytological types II and III are rare. The majority of cases are of
      type I. Of the latter, tumours in TNM stage I were not found in the necropsy
      series, while infiltrating duct carcinomas of type I TNM stage II were also
      absent. This suggests that the possibility of surgical cure may be better in type
      I duct carcinomas in stage II than with other histological types. Prolonged
      survival in contrast to surgical cure was related to type III tumours
      irrespective of TNM stage.

PMID- 4356266
TI  - "Sclerosing haemangioma" of the lung: an alternative view of its development.
AB  - ;Sclerosing haemangioma' is a name which has been applied to a group of uncommon
      benign pulmonary lesions characterized by their papillary nature, a sclerotic
      stroma containing lipid, and, in some cases, evidence of haemorrhage. There is
      little evidence that these lesions are really angiomatous. Studies of two
      examples removed surgically after being discovered as incidental radiographic
      findings, show that the cells lining the papillae have large vacuoles which
      contain whorled, electron-dense inclusions. These epithelial cells have the
      features of granular pneumonocytes, cells known to contain phospholipid. Both
      lipid and cholesterol are abundant in the stroma of both tumours and the lipid is
      distributed in a nodular fashion. Histochemically the lipid gives a strong
      reaction to stains for phospholipid and it is suggested that the lipid is
      derived, not from the haemorrhage, but is produced by the epithelial element of
      the tumour.

PMID- 4356268
TI  - [Analysis of toxicity in intermittent ethambutol-medication (author's transl)].

PMID- 4356267
TI  - The traditional oriental medicine and acupuncture therapy.

PMID- 4356269
TI  - Methodology for separation of gangliosides from potential water-soluble
      precursors.

PMID- 4356270
TI  - D-galactosamine induced fatty liver. II. Analyses of hepatic lipid compositions.

PMID- 4356272
TI  - Whooping cough in Melbourne.

PMID- 4356271
TI  - Antagonistic effects of Myxococcus xanthus on fungi. II. Isolation and
      characterization of inhibitory lipid factors.

PMID- 4356273
TI  - The mechanism of initiation of parturition in the ewe.

PMID- 4356274
TI  - Protein kinases: aspects of their regulation and diversity.

PMID- 4356275
TI  - The role of phospholipids in hormone activation of adenylate cyclase.

PMID- 4356276
TI  - Hormonal regulation of gene expression in mammary cells.

PMID- 4356277
TI  - Studies on luteinizing hormone and its subunits: development and application of a
      radioligand receptor assay and properties of the hormone-receptor interaction.

PMID- 4356278
TI  - Androgen metabolism and mechanism of action in male pseudohermaphroditism: a
      study of testicular feminization.

PMID- 4356279
TI  - [Dental consequences of a mandibular injury in childhood].

PMID- 4356280
TI  - Bicyclic phosphorus esters: high toxicity without cholinesterase inhibition.
AB  - 4-Isopropyl-2,6,7-trioxa-1-phosphabicyclo[2.2.2]octane 1-oxide has a mouse
      intraperitoneal lethal dose, 50 percent effective, of 0.18 milligram per kilogram
      of body weight. Related compounds used by many chemical researchers are also
      highly toxic. Brain acetylcholinesterase inhibition is not involved in their mode
      of action. The structural similarity of these compounds to adenosine 3',5'
      monophosphate (cyclic AMP) is of interest.

PMID- 4356281
TI  - Xenotropic viruses: murine leukemia viruses associated with NIH Swiss, NZB, and
      other mouse strains.
AB  - Murine leukemia virus activity is present in tissues from NIH Swiss and other
      mouse strains after cocultivation with nonvirus-yielding rat cells transformed by
      Harvey sarcoma virus. The resulting pseudotype sarcoma virus has the same type
      specific coat as the virus previously isolated from New Zealand black (NZB) mice,
      and, like the NZB virus, it is unable to infect mouse cells. The results show
      that this NZB type virus is endogenous in other strains of mice and is
      xenotropic; that is, it grows only in cells foreign to the host. This is the
      first clear demonstration that NIH Swiss mice also carry indigenous infectious
      murine leukemia virus.

PMID- 4356282
TI  - Gas chromatographic analysis of drugs and drug metabolites in biological samples.

PMID- 4356284
TI  - [The lipid composition of healthy and pathological skin areas in Psoriasis
      vulgaris (author's transl)].

PMID- 4356283
TI  - [The differentiation of Lp(a)-lipoprotein with the aid of agarose gel
      electrophoresis (author's transl)].

PMID- 4356286
TI  - [Comparison of different methods for the serological determination of alpha1
      foetoprotein in serum (author's transl)].

PMID- 4356285
TI  - [Homotropic cooperative effects and rising B-F-curves in hormone-antibody
      reactions (author's transl)].

PMID- 4356287
TI  - [Methodological difficulties in the determination of steroid hormones by protein
      binding methods (author's transl)].

PMID- 4356288
TI  - On the estimation of some demographic characteristics on a prehistoric population
      from the American Southwest.

PMID- 4356289
TI  - A new enzymatic method for the determination of inorganic phosphate and its
      application to the nucleoside diphosphatase assay.

PMID- 4356290
TI  - Concentration and purification of two small RNA viruses: mycophage PS-1 and
      bacteriophage phi6.

PMID- 4356291
TI  - Interference by ascorbate-2-sulfate in the dinitrophenylhydrazine assay of
      ascorbic acid.

PMID- 4356292
TI  - The diurnal variation of peptidyl proline hydroxylase activity in different
      tissues of the rat.

PMID- 4356293
TI  - Insulin degradation. 8. Protein thiols as co-substrates for glutathione-insulin
      transhydrogenase.

PMID- 4356294
TI  - Studies on estrogen entry into uterine cells and on estradiol-receptor complex
      attachment to the nucleus--is the entry of estrogen into uterine cells a protein
      mediated process?

PMID- 4356295
TI  - Degradation of thyroxine by microsomal particles from rat liver. II. Purification
      of Fe2+-dependent particles and some of their properties.

PMID- 4356296
TI  - Occurrence and biosynthesis of adenosine 3',5'-cyclic monophosphate in isolated
      Avena etioplasts.

PMID- 4356297
TI  - Biosynthesis of NAD in Haemophilus haemoglobinophilus.

PMID- 4356298
TI  - Myocardial adenosine kinase: activity and localization determined with rapid,
      radiometric assay.

PMID- 4356300
TI  - Improved synthesis of 32P-labelled 3',5'-cyclic GMP and other 3',5'-cyclic ribo-
      and deoxyribonucleotides of high specific activity.

PMID- 4356299
TI  - Iron-ATP, a by-product of acid extraction of whole blood or red blood cells.

PMID- 4356301
TI  - The effects of delta 1-tetrahydrocannabinol on cyclic AMP levels in WI-38
      fibroblasts.

PMID- 4356303
TI  - Phosphoenolpyruvate:fructose phosphotransferase activity in whole cells and
      membrane vesicles of Arthrobacter pyridinolis.

PMID- 4356302
TI  - Stimulation of purified muscle protein kinase by cyclic AMP and its butyrated
      derivatives.

PMID- 4356305
TI  - Model discrimination and nonlinear parameter estimation in the analysis of the
      mechanism of action of beta-hydroxybutyrate dehydrogenase from Rhodopseudomonas
      spheroides.

PMID- 4356304
TI  - On the nature of the serum enzyme catalyzing paraoxon hydrolysis.

PMID- 4356306
TI  - Alterations in the levels of peptide hydrolases and other enzymes in brush-border
      and soluble fractions of rat small intestinal mucosa during starvation and
      refeeding.

PMID- 4356307
TI  - Localization of 3-beta hydroxysteroid dehydrogenase in the inner membrane
      subfraction of rat testis mitochondria.

PMID- 4356308
TI  - Inorganic pyrophosphate-phosphohydrolytic activity in human serum. Catalytic
      properties of the ionic species of PPi and MgPPi complexes.

PMID- 4356310
TI  - Epinephrine- and prostaglandin-sensitive adenyl cyclase in mammary gland.

PMID- 4356309
TI  - Polyphosphate phosphohydrolase from Endomyces magnusii.

PMID- 4356311
TI  - Interactions of succinate dehydrogenase with cyanide.

PMID- 4356312
TI  - Intracellular localization of superoxide dismutase and its relation to the
      distribution and mechanism of hydrogen peroxide-producting enzymes.

PMID- 4356313
TI  - Influence of pyrophosphate on the exchange of calcium and phosphate ions on
      hydroxyapatite.

PMID- 4356314
TI  - Active and passive immunity to bovine viral respiratory diseases in beef calves
      after shipment.
AB  - Fifteen steers were vaccinated after shipment with a modified live virus vaccine
      containing infectious bovine rhinotracheitis (IBR), bovine virus diarrhea (BVD),
      and bovine myxovirus parainfluenza-3 (PI3), and 16 unvaccinated steers were kept
      as controls. Geometric mean titers one month after vaccination were highest to
      BVD, followed by PI3 and IBR. Weight gains were higher during 30 days after
      vaccination in the controls. One case of acute respiratory disease developed in
      one vaccinated calf. Revaccination 79 days after the first dose increased
      antibody to PI3 and BVD virus but not IBR. In a second trial, no clinical
      respiratory disease developed after shipment of 13 heifers that received an
      antibacterial-antiviral antiserum or in the 12 controls. Weight gains 30 days
      after shipment were identical in both groups.

PMID- 4356315
TI  - Infectious bursal disease in New Brunswick.
AB  - A flock of four week old chickens experienced a disease of sudden onset in which
      the only symptoms were those of depression shortly before death, and in which the
      predominant histological lesion was necrosis of lymphocytes in the bursa of
      Fabricius.A virus, designated strain Sk-1, was isolated from pooled bursal tissue
      of affected birds and was serologically identified as a strain of the infectious
      bursal agent. This virus was chloroform resistant, did not hemagglutinate guinea
      pig or chicken erythrocytes and did not produce a cytopathic effect in chick
      embryo tissue cultures. Equivocal results were obtained in filtration studies but
      the agent was less than 100nm in diameter. Four week old chicks inoculated with
      strain Sk-1 developed microscopic lesions in the bursa of Fabricius which were
      similar to those seen in the original field specimens. Inoculated chick embryos
      exhibited characteristic macroscopic lesions and necrosis of vascular tissue was
      a common histological change.A limited serological survey of local poultry flocks
      indicated that infection by this agent had occurred in four of the ten flocks
      examined.

PMID- 4356317
TI  - [A contribution to the diagnostics of whooping cough].

PMID- 4356316
TI  - Observations of cattle, goats and pigs after administration of synthetic
      interferon inducers and subsequent exposure to foot and mouth disease virus.
AB  - Polyriboinosinic-polyribocytidylic acid (poly [rI.rC]) was administered
      intravenously to 11 cattle and 13 goats in doses of 0.25 to 4.0, and 1.0 to 5.0
      mg/kg, respectively. Subsequent exposure of these and untreated control animals
      to foot and mouth disease virus (FMDV) failed to demonstrate any differences in
      either the course or severity of the disease. Serum interferon was detected in
      cattle one hour after the intravenous administration of poly (rI.rC). Six pigs
      given 4, 20, or 100 mg/kg of itaconic-acrylic acid copolymer (IAA, HMW)
      intraperitoneally reacted clinically the same as six untreated control pigs after
      contact exposure to FMDV. Three pigs given 50, 100, or 200 mg/kg of divinyl ether
      maleic anhydride copolymer (DVE/MA, pyran) intraperitoneally similarly failed to
      show any difference in clinical reaction from three untreated control pigs after
      intranasal instillation of FMDV. Three pigs given 100, 200 or 400 mg/kg of DVE/MA
      intraperitoneally developed rapid diffuse peritonitis causing the death of one in
      48 hours.

PMID- 4356318
TI  - [Importance of plasmids in staphylococci (author's transl)].

PMID- 4356319
TI  - Outpatient management of chronic schizophrenics with fluphenazine enanthate
      (Prolixin enanthate): a clinical evaluation.

PMID- 4356320
TI  - Separation and detection of 35S-labelled taurine, isethionic acid and sulfate.

PMID- 4356321
TI  - The subunits of L-glutamate decarboxylase from Clostridium perfringens.

PMID- 4356322
TI  - Electrophoretic characterization of bovine serum lipoproteins throughout
      gestation and lactation.

PMID- 4356324
TI  - Quantitation of mouse mammary tumor virus (MTV) virions by radioimmunoassay.

PMID- 4356323
TI  - Immune complex glomerulonephritis in one-year-old C57BL-6 mice induced by
      endogenous murine leukemia virus and erythrocyte antigens.

PMID- 4356325
TI  - Decreased epinephrine response of adenylate cyclase activity of lymphoid cells
      from immunodeficient pituitary dwarf mice.

PMID- 4356326
TI  - Production and properties of migration inhibitory factor and interferon in the
      circulation of mice with delayed hypersensitivity.

PMID- 4356327
TI  - Characterization of a second normal antigen that cross-reacts with CEA.

PMID- 4356328
TI  - The electromyogram in facial myokymia and hemifacial spasm.

PMID- 4356329
TI  - Unsuspected lymphosarcoma of the kidneys diagnosed as bilateral Wilms tumor.

PMID- 4356331
TI  - Studies on the prevalence of Salmonella serotypes in nonhuman primates.

PMID- 4356330
TI  - Canine renal allografts hyperacute rejection: an experimental model for studies
      on treatment.

PMID- 4356332
TI  - A simple method for determining erythrocyte survival in rats using slchromium.

PMID- 4356333
TI  - Latent Pasteurella pneumotropica infection of the gnotobiotic and barrier-held
      rats.

PMID- 4356334
TI  - Strain differences in the response of rats to repeated injections of
      pentobarbital sodium.

PMID- 4356335
TI  - Variability of embryonic development in the rabbit at 19 to 168 hours after
      mating.

PMID- 4356336
TI  - Development of a Pasteurella-free rabbit colony.

PMID- 4356337
TI  - Mode of killing and plasma corticosterone concentrations in the rat.

PMID- 4356338
TI  - The rabbit pyrogen test.

PMID- 4356339
TI  - A method for intragastric feeding of neonatal rats.

PMID- 4356340
TI  - A safe and efficient handling device for wild rodents.

PMID- 4356341
TI  - Apparatus facilitating intravenous injections in dogs.

PMID- 4356342
TI  - The hemogram and bone marrow profile of normal neonatal and weanling beagle dogs.

PMID- 4356343
TI  - Actinomycosis in a primate confirmed by fluorescent antibody technics in formalin
      fixed tissue.

PMID- 4356344
TI  - A rapid screening program for the diagnosis of Dirofilaria immitis infections in
      dogs.

PMID- 4356345
TI  - Hemoglobins, haptoglobins, and transferrins in beagles.

PMID- 4356346
TI  - A discrimination problem for restrained beagles.

PMID- 4356347
TI  - The miniature pig: a biomedical model for behavioral studies.

PMID- 4356348
TI  - Urinary bladder carcinoma in a rhesus monkey (Macaca mulatta): a literature
      review and case report.

PMID- 4356349
TI  - Self-mutilation following Innovar-Vet injection in the guinea pig.

PMID- 4356350
TI  - Naturally-occurring and experimentally-induced arthritides in rodents: a review
      of the literature.

PMID- 4356351
TI  - Letter: Laboratory animal medicine.

PMID- 4356352
TI  - Effect of ethanol on cyclic AMP levels in the rat brain.

PMID- 4356353
TI  - [The reactions of auditory cortex neurons to stimulation of geniculocortical
      fibers].

PMID- 4356354
TI  - [Connections between cat somatosensory cortex neurons and thalamic relay nuclei].

PMID- 4356355
TI  - [Monosynaptic excitation of facial nerve nucleus neurons upon electrical
      stimulation of the red nucleus].

PMID- 4356356
TI  - [Synaptic processes in thoracic motor neurons evoked by visceral impulsation].

PMID- 4356357
TI  - [Characteristics of the interaction between the central neurons and abdominal
      stretch receptors of the crayfish].

PMID- 4356358
TI  - The role of spinal cord facilitation in neurogenic bladder function.

PMID- 4356359
TI  - [Change in the reactivity of the cardiovascular system in experimental renal
      hypertension].

PMID- 4356361
TI  - Localized neurogenic vasoconstriction of the basilar artery.

PMID- 4356360
TI  - [Semeiological and evolutive aspects of tumors of the pineal body and of the
      pineal region studied in the light of 52 cases].

PMID- 4356362
TI  - Subcellular localization of human placental aryl hydrocarbon hydroxylase.

PMID- 4356363
TI  - Structure-activity relationships in drug-induced pancreatic islet cell toxicity.

PMID- 4356364
TI  - Action of black widow spider venom at insect neuromuscular junctions.

PMID- 4356365
TI  - [Adrenal glucocorticoid function during removal of tumors of the cerebral
      hemispheres].

PMID- 4356366
TI  - [Mineralocorticoid function of the adrenal cortex in intracranial neoplasms].

PMID- 4356368
TI  - [Roentgenologic findings in the diagnosis of intracerebral tumors in the region
      of the ventricular trigone].

PMID- 4356367
TI  - [Blood loss during removal of brain tumors].

PMID- 4356370
TI  - [The dynamics of serum growth hormone concentration in patients with hypophyseal
      tumors following surgery].

PMID- 4356369
TI  - [A histochemical study of the acid phosphatase activity of macroglial brain
      tumors].

PMID- 4356371
TI  - [The differential diagnosis of chronic traumatic subdural hematomas and gliomas
      of the cerebral hemispheres in the aged].

PMID- 4356372
TI  - The inactivation of foot-and-mouth disease virus by ethylenimine and
      propylenimine.

PMID- 4356373
TI  - [Excretion of rhinopneumonitis virus in the semen of the stallion].

PMID- 4356374
TI  - [Neurogenic tumors in the mediastinum].

PMID- 4356375
TI  - Incidence of hepatitis associated antigen in chronic liver disease in Southern
      Italy.

PMID- 4356376
TI  - Lateral line input to the crista cerebellaris in the eel. Field potentials and
      histology.

PMID- 4356377
TI  - Nucleoside phosphomonesterases: an hypothesis on their physiological role in
      sporulating bacteria.

PMID- 4356378
TI  - Indirect coulometric titration of biological electron transport components.

PMID- 4356379
TI  - [TSH, HGH, ACTH, LH plasma levels in patients with pituitary disease (author's
      transl)].

PMID- 4356380
TI  - [Metastatic malignant pancreatic tumor. Disappearance of symptoms 6 months after
      streptozotocin treatment (author's transl)].

PMID- 4356381
TI  - [Clinical applications of radioimmunoassay of plasma parathyroid hormone
      (author's transl)].

PMID- 4356382
TI  - [Possible reasons for the development of morphological changes in the liver
      during viral hepatitis].

PMID- 4356383
TI  - [Ultrastructural changes in the plasma membrane of cells in pathological
      conditions].

PMID- 4356384
TI  - Inhibition of cyclic AMP formation and lipolysis in rat adipose tissue by
      nicotinic acid.

PMID- 4356386
TI  - Quantitative studies on fibrinogen and low-density lipoprotein in human aortic
      intima.

PMID- 4356385
TI  - Plasma lipoproteins of turkeys injected with a single dose of diethylstilbestrol.

PMID- 4356388
TI  - The long-term solubility of a stannous fluoride-zinc phosphate cement.

PMID- 4356387
TI  - Trial of an anabolic steroid (oxymetholone) in atherosclerosis with
      hyperlipoproteinaemia.

PMID- 4356389
TI  - The respiratory chain of Azotobacter vinelandii. II. The effect of cyanide on
      cytochrome d.

PMID- 4356391
TI  - Purification of the human intestinal brush border membrane.

PMID- 4356390
TI  - Fusion of mammalian cells by unilamellar lipid vesicles: inflluence of lipid
      surface charge, fluidity and cholesterol.

PMID- 4356392
TI  - [Characteristics of the structure of the electron-transport chain of bacterial
      photosynthesis].

PMID- 4356393
TI  - [Time of exposure to vibration in the development of symptoms of peripheral
      autonomic syndrome in upper extremities].

PMID- 4356394
TI  - Chemotherapy of Morris hepatoma 3924A: correlation of size and weight of tumor
      and preliminary data with 5-fluoro-2'-deoxyuridine (5-FUDR; NSC-27640).

PMID- 4356396
TI  - Preliminary clinical trials of butocin (NSC-172755) in patients with generalized
      carcinoma of the breast.

PMID- 4356395
TI  - Effect of streptonigrin (NSC-45383) and analogs on oncornavirus replication and
      DNA polymerase activity.

PMID- 4356397
TI  - The reaction of ammonia with acylated disaccharides. X. Octa-O-benzoyl-lactose
      and other benzoyl derivatives of lactose.

PMID- 4356399
TI  - Degradation of dextrans by an alpha-1,6-glucan glucohydrolase from Streptococcus
      mitis.

PMID- 4356398
TI  - Studies of polysaccharide structure. I. A modification of the Smith degradation.

PMID- 4356400
TI  - The molecular structures of a glucan and a galactan synthesised by Prototheca
      zopfii.

PMID- 4356401
TI  - The methanesulfonylation of 2-benzimidazolemethanol and alpha-(2
      benzimidazolyl)benzyl alcohol.

PMID- 4356402
TI  - [Cyclic AMP and some disease processes (author's transl)].

PMID- 4356403
TI  - Alpha-fetoprotein and Australia antigen in primary liver cancer.

PMID- 4356404
TI  - [Role of cellular repair mechanisms in the realization of spontaneous and induced
      mutations in vertebrate viruses].

PMID- 4356405
TI  - [Reduction of cytochrome C in the presence of quinones; effect of light].

PMID- 4356406
TI  - [Use of paramagnetic probes for revealing conformational changes in Na+, K+ 
      dependent ATPase].

PMID- 4356408
TI  - [Conjugated estrogens for therapy of the climacterium].

PMID- 4356407
TI  - [Synthesis and biochemical identification of serotonin O-glucuronide].

PMID- 4356409
TI  - [Hazards to mother and child through disease during pregnancy].

PMID- 4356410
TI  - Initiation of globin synthesis in rabbit reticulocyte cell-free systems:
      inhibition by double-stranded RNA.

PMID- 4356411
TI  - Haemoglobin and polypeptide biosynthesis by polyribosomes and ribosomal
      subparticles.

PMID- 4356412
TI  - Structural alterations and content of nicotinamide-adenine nucleotides in
      skeletal muscle of rat in chronic experimental carbon disulfide intoxication.

PMID- 4356413
TI  - Structural aspects of experimental carbon disulfide neuropathy. I. Development of
      neurohistological changes in chronically intoxicated rats.

PMID- 4356414
TI  - Hair cell interactions in the statocyst of Hermissenda.
AB  - Hair cells in the statocyst of Hermissenda crassicornis respond to mechanical
      stimulation with a short latency (<2 ms) depolarizing generator potential that is
      followed by hyperpolarization and inhibition of spike activity. Mechanically
      evoked hyperpolarization and spike inhibition were abolished by cutting the
      static nerve, repetitive mechanical stimulation, tetrodotoxin (TTX), and Co(++).
      Since none of these procedures markedly altered the generator potential it was
      concluded that the hyperpolarization is an inhibitory synaptic potential and not
      a component of the mechanotransduction process. Intracellular recordings from
      pairs of hair cells in the same statocyst and in statocysts on opposite sides of
      the brain revealed that hair cells are connected by chemical and/or electrical
      synapses. All chemical interactions were inhibitory. Hyperpolarization and spike
      inhibition result from inhibitory interactions between hair cells in the same and
      in opposite statocysts.

PMID- 4356415
TI  - The fibrous components of bovine ligamentum nuchae observed in the scanning
      electron microscope.

PMID- 4356416
TI  - Strychnine, morphine and monamine depression.

PMID- 4356417
TI  - The effect of local anaesthetic agents on lipolysis by human adipose tissue.

PMID- 4356418
TI  - Effect of a highly purified phospholipase C on some electrophysiological
      properties of the frog muscle fibre membrane.

PMID- 4356419
TI  - The metabolism of (ureyl-14C)tolbutamide in vitro and in vivo in man.

PMID- 4356420
TI  - [Vitamin-D-resistant forms of rickets].

PMID- 4356421
TI  - [Quantitative skeletal mineral salt determination in genuine vitamin-D-resistant
      rickets during long-term vitamin D therapy].

PMID- 4356422
TI  - [Adriamycin in the therapy of child leukemias and tumors].

PMID- 4356424
TI  - Nursing care study: pancreatic dermatosis.

PMID- 4356423
TI  - [Evaluation of cytosine arabinoside therapy in congenital cytomegalovirus
      diseases].

PMID- 4356425
TI  - General model for the molecular events in synapses during learning.

PMID- 4356426
TI  - [Myocardial infarct in the young adult].

PMID- 4356427
TI  - [Diagnostic and therapeutic indications of auricular stimulation].

PMID- 4356429
TI  - [Portal hypertension due to arterio-venous aneurysm of the right gastroepiploic
      vessels following gastrectomy].

PMID- 4356428
TI  - [Thrombolytic urokinase treatment of very severe pulmonary embolism. Apropos of 6
      cases].

PMID- 4356430
TI  - [Current results of cancer detection].

PMID- 4356431
TI  - Parthenogenesis in birds.

PMID- 4356432
TI  - The incidence of malignant tumours in the mouth-pharynx region in Sweden 1958
      1967.

PMID- 4356433
TI  - The histochemical mapping of "chemical pathways" in the central nervous system.

PMID- 4356434
TI  - [The chemistry of transmitters].

PMID- 4356436
TI  - [Mode of action of tricyclic antidepressants].

PMID- 4356435
TI  - [Theories on the models of action of antipsychotic drugs].

PMID- 4356437
TI  - [Breast cancer and virus].

PMID- 4356438
TI  - [Immunosuppressive treatment in neurological disorders].

PMID- 4356439
TI  - [Equine infectious anemia--recent researches and prospect of the study (author's
      transl)].

PMID- 4356440
TI  - [Virologic and serologic studies on infectious mononucleosis-like illness in
      children (author's transl)].

PMID- 4356441
TI  - [Effect of neonatal thymectomy on the experimental enteric infection of germfree
      mice with a mouse adenovirus (author's transl)].

PMID- 4356442
TI  - [Effect of antilymphocyte serum on the time course of experimental enteric
      infection of mice with a mouse adenovirus (author's transl)].

PMID- 4356443
TI  - [Survey on foot and mouth disease in Thailand].

PMID- 4356444
TI  - Pseudomonas cytochrome c peroxidase. VII. Kinetics of the peroxidatic reaction
      mechanism.

PMID- 4356445
TI  - Pseudomonas cytochrome c peroxidase. 8. The amino acid composition of the enzyme.

PMID- 4356446
TI  - Evidence for a human oncogenic virus.

PMID- 4356447
TI  - Cerebrospinal fluid cytomorphology using cytocentrifugation.

PMID- 4356448
TI  - The role of the platelet membrane in platelet function. II. 5-Hydroxytryptamine
      (serotonin) uptake.

PMID- 4356449
TI  - Eosinophilic Pelger-Huet anomaly with myeloproliferative disorder.

PMID- 4356450
TI  - Isolation of viruses from single throat swabs processed for diagnosis of group A
      beta-hemolytic streptococci by fluorescent antibody technic.

PMID- 4356451
TI  - Urine testing: a comparison of five current methods for detecting morphine.

PMID- 4356453
TI  - Demeclocycline-induced nephrogenic diabetes insipidus. In-vivo and in-vitro
      studies.

PMID- 4356452
TI  - Pentose pathway and production of reduced nicotinamide adenine dinucleotide
      phosphate. A mechanism that may protect lungs from oxidants.

PMID- 4356454
TI  - Letter: Asymptomatic cytomegalovirus mononucleosis.

PMID- 4356455
TI  - Endothelial inclusions and "nuclear bodies" in systemic lupus erythematosus.

PMID- 4356456
TI  - Suppression of herpes simplex virus infection by phosphonoacetic acid.
AB  - Disodium phosphonoacetate when administered orally or topically to mice
      experimentally infected with herpes simplex virus was able to significantly
      reduce the mortality associated with the agent. In addition, this compound was
      able to reduce herpesvirus lesions on the corneas of infected rabbits.

PMID- 4356457
TI  - Inactivation of Clostridium perfringens type A spores at ultrahigh temperatures.
AB  - The inactivation of Clostridium perfringens type A spores (three strains of
      different heat resistances) at ultrahigh temperatures was studied. Aqueous spore
      suspensions were heated at 85 to 135 C by the capillary tube method. When
      survivors were enumerated on the standard plating medium, the spores appeared to
      have been rapidly inactivated at temperatures above 100 C. The addition of
      lysozyme to the plating medium did not affect the recovery of spores surviving
      the early stages of heating, but lysozyme was required for maximal recovery of
      spores surviving extended heat treatments. The percentage of survivors requiring
      lysozyme for colony formation increased greatly with longer exposure times or
      increasing treatment temperature. Time-survivor curves indicated that each spore
      suspension was heterogeneous with respect to the heat resistance of spore
      outgrowth system or in the sensitivity of the spores to lysozyme. Recovery of
      survivors on the lysozyme containing medium revealed greater heat resistance for
      one strain than has been reported for spores of many mesophilic aerobes and
      anaerobes. The spores of all three strains were more resistant to heat
      inactivation when suspended in phosphate buffer, but a greater percentage of the
      survivors required lysozyme for colony formation.

PMID- 4356458
TI  - Sand beach bacteria: enumeration and characterization.
AB  - Bacteria in the water-saturated sand of a relatively unpolluted sand beach were
      enumerated by direct microscope and viable counting. The number of interstitial
      bacteria was estimated to be a significant fraction of the total number of
      bacteria present. Three hundred sixty-two strains were isolated and submitted to
      cultural and biochemical tests. Fermentational abilities and the production of
      indole suggested that a significant number of these bacteria were symbiotically
      associated with resident metazoans.

PMID- 4356459
TI  - Silica gel medium for enumeration of petroleumlytic microorganisms in the marine
      environment.
AB  - A silica gel medium was developed for the enumeration of petroleumlytic
      microorganisms in the marine environment. The medium was satisfactorily used for
      the investigation of the vertical distribution of bacteria in seawater from the
      surface to 1,000 m depth of western north Pacific central water as well as the
      neritic region of Japan.

PMID- 4356460
TI  - Direct immunofluorescence test for the diagnosis of genital herpesvirus
      infections.
AB  - Herpetic lesions of the genitalia may be confused clinically with other
      ulcerative, genital lesions. Direct immunofluorescence (FA) provides a rapid
      method of diagnosis, and the utility of this method for the diagnosis of genital
      ulcers was examined. One hundred and ten patients with genital lesions were
      examined by darkfield for syphilis and by FA and culture for herpes simplex virus
      (HSV) infections. Satisfactory samples were obtained from 102 patients, of which
      81 were clinically suspected cases of HSV. Acetone-fixed slides of scrapings of
      ulcerative lesions were stained with conjugated antiserum prepared in rabbits
      against HSV type 2. HSV was isolated from 73% of specimens of suspected herpetic
      lesions, and 77% of these specimens were positive by FA. Nine percent were
      positive by FA only and these were not thought to represent false positives. Five
      percent were positive by culture only. A comparison of clinical diagnoses with
      laboratory findings revealed that 4% of the cases were misdiagnosed when only the
      clinical evaluation was considered. The data suggest that the inclusion of a
      diagnostic FA test for HSV along with the darkfield examination may be useful for
      differentiating the etiological agents of ulcerative, genital lesions.

PMID- 4356461
TI  - In vitro production of Clostridium perfringens enterotoxin and its detection by
      reversed passive hemagglutination.
AB  - The reversed passive hemagglutination (RPHA) test yielded a positive reaction in
      2 h with as little as 0.5 ng of purified Clostridium perfringens enterotoxin
      (CPE) per ml as well as with cultures of some C. perfringens grown in Duncan
      Strong (DS) medium. This method is the most sensitive, the simplest, and the
      fastest among all reported. The time course of CPE production of Clostridium
      perfringens NCTC 8798 in DS was investigated by RPHA. CPE in culture was
      detectable at 4 h, increased gradually, reached a maximum at 12 to 14 h, and
      remained at a high level of 20 mug/ml through 48 h of incubation. CPE synthesized
      within cells is released easily by sonic disruption of young cultures and by
      aging the cultures 20 h or more. Heat shock of the cell inoculum was essential
      for CPE production by C. perfringens in DS.

PMID- 4356463
TI  - Quantitative extraction of adenosine triphosphate from cultivable and host-grown
      microbes: calculation of adenosine triphosphate pools.
AB  - EXISTING DATA ON ADENOSINE TRIPHOSPHATE (ATP) POOLS IN MICROBES ARE DEFICIENT FOR
      TWO REASONS: (i) incomplete extractions of ATP, and (ii) the failure to take into
      account that the adverse effects of extracting procedures on standard ATP exert
      analogous effects on the ATP released from bacterial cells. Methods for
      correcting observed yields and calculating ATP pools have been demonstrated.
      Three bacterial species were used in the studies on extraction of ATP:
      Escherichia coli, Mycobacterium phlei, and Mycobacterium lepraemurium. Perchloric
      acid and n-butanol were disqualified because of their failure to extract total
      bacterial ATP even from E. coli and because of inconvenient procedures. The new
      extraction procedure had minimal effects on standard ATP, liberated 100% of the
      ATP pools from the three representative species of microbes, and caused no ionic
      imbalance or quenching of bioluminescence. This method involves vortexing of cell
      suspensions for 10 s with 23% chloroform (vol/vol), heating at 98 C for the
      required time (E. coli, 3 min; M. phlei, 5 min; M. lepraemurium, 10 min) and then
      1 min at 98 C with vacuum to dry the samples. Heat or chloroform alone may
      suffice for some microbes and release total ATP from plant and animal cells.

PMID- 4356462
TI  - Biodegradation of o-benzyl-p-chlorophenol.
AB  - The extent of biodegradation of o-benzyl-p-chlorophenol, marketed as a germicide
      under the name Santophen((R)) 1 (Monsanto Co.), in river water, sewage, and
      activated sludge was determined. Biodegradation was assessed by use of a
      colorimetric procedure for phenolic materials, carbon analysis, and CO(2)
      evolution. In unacclimated river water, 0.1 mg of Santophen 1 per liter was
      degraded within 6 days. In sewage, 0.5 and 1.0 mg/liter levels of Santophen 1
      were degraded in 1 day. Acclimated activated sludge achieved 80% biodegradation
      of 1.0 mg/liter Santophen 1 in 8 h and 100% in 24 h. When effluent from a
      semicontinuous activated sludge unit, acclimated to 20 mg of Santophen 1 per
      liter was used as the inoculum for the CO(2) evolution procedure, 60% of the
      total theoretical CO(2) was evolved from Santophen 1. Based on the results of
      these studies, indicating Santophen 1 to be readily biodegraded in at least four
      biological systems, the continued use of present levels of Santophen 1 should
      present no significant environmental problems.

PMID- 4356464
TI  - Complement-fixing antigens produced by varicella-zoster virus in tissue culture.
AB  - The complement-fixing antigens present in tissue cultures infected with varicella
      zoster virus were separated into four components. There were (i) a cell-free
      soluble antigen, (ii) a cell-associated soluble antigen, (iii) a cell membrane
      associated antigen, and (iv) a virion antigen. All four antigens were reactive
      with sera from patients with varicella or zoster, and about 90% of the total
      complement-fixing activity was found to be nonvirion associated.

PMID- 4356465
TI  - Medium for the selective enumeration of lactic acid bacteria from foods.
AB  - A nitrite actidione polymyxin agar was developed for the enumeration of lactic
      acid bacteria. It was effective in recovering organisms from pure cultures and
      from foods.

PMID- 4356466
TI  - Large-scale purification of ribonucleic acid tumor viruses by use of continuous
      flow density gradient centrifugation.
AB  - This report describes a 200- to 300-fold increase in the quantity of ribonucleic
      acud tumor virus particles previously isolated at one time by zonal
      centrifugation.

PMID- 4356467
TI  - Comparison of methods for the recovery of virus inoculated into ground beef.
AB  - Various methods for the recovery of virus inoculated into ground beef were
      investigated in an attempt to develop a sensitive system that could be used to
      detect viral contaminants in market foods. A 100-g sample, inoculated with
      poliovirus 1, was suspended in 150 to 900 ml of Eagle minimum essential medium,
      pH 8.5, and mixed in either plastic bags or plastic cups on a mechanical shaker.
      The particulate materials were removed by means of cheese cloth, glass wool,
      woven fiber glass, or low-speed centrifugation. Large volumes of fluid were
      concentrated by ultrafiltration. Microbiological contamination was controlled by
      high antibiotic concentrations or by filtration. Quantitative plaque-forming-unit
      recovery of the virus was determined by utilizing an agar overlay technique on
      Vero cell cultures. The data indicated that from 20 to 50% of the seeded virus
      could be recovered from a 100-g sample of ground beef. The glass wool and woven
      fiber glass methods were the most effective, with recovery of approximately 50%
      of the inoculated virus.

PMID- 4356468
TI  - Enterovirus recovery with vegetable floc.
AB  - A lettuce floc was prepared and used for recovering enterovirus from an aqueous
      suspension. The method is simple, and the adsorption of coxsackievirus B5,
      echovirus 7, and poliovirus 1 is quantitative. The virus-floc complex may be
      removed from aqueous suspension by low-speed centrifugation and dissolved at an
      alkaline pH in a small volume of water; virus is then available for assay on
      cultured cells. Flocs from some other green vegetables also possess the property
      of virus adsorption

PMID- 4356469
TI  - Isolation and characterization of corynebacteria from burned children.
AB  - A total of 221 strains of corynebacteria were isolated and characterized by
      methods which included tests encompassing five schemes proposed for grouping
      cutaneous diphtheroids. Seventy-one strains (group I) were isolated from the
      hospital air in patient areas and from the normal skins of children admitted for
      reconstructive surgery of old healed burns and from the normal skins of nursing
      personnel. One hundred and fifty strains (group II) were isolated from various
      clinical specimens and from normal skins of a population of acutely burned
      children. The majority of the strains in group I were lipophilic and contained
      the largest number of fluorescent strains. Among the group II strains, there was
      a subgroup which was nonsusceptible to oxacillin, lincomycin, erythromycin, and
      kanamycin and also had in common the fermentation of glucose and galactose,
      reduction of both nitrate and nitrite, and growth on 40% bile agar. These strains
      were the most commonly recognized types isolated from acutely burned patients and
      possibly originated from the patient's intestinal tract. Data indicated that the
      air was not a means of transmission for these corynebacteria among acute
      patients. Corynebacteria were isolated from 11% of the burn wound cultures by
      using a selective medium but were found in 66% of the acute patients. Over 90% of
      the strains in groups I and II did not conform sufficiently with described
      characteristics of common human indigenous corynebacteria to be accurately
      speciated.

PMID- 4356470
TI  - Complement-fixation analysis of four subtypes of foot-and-mouth disease virus
      type A.
AB  - Complement-fixation patterns were established for four subtypes of foot-and-mouth
      disease virus by block assays against homologous and heterologous antiserum.
      Inhibition of fixation by excess antigen was observed in most homologous systems
      but rarely in the heterologous systems. The heterologous antibody titers were, in
      all instances, considerably lower than those for the homologous systems. Although
      relatively high dilutions of antiserum may be desirable for subtyping, higher
      concentrations of antibody should be used for determining serological types.

PMID- 4356471
TI  - Microcomplement-fixation inhibition: a rapid and economical test to detect non
      complement-fixing antibodies.
AB  - Complement-fixation inhibition test was adapted to the microtiter system. When
      cat and monkey non-complement-fixing antibody were used, the microtest was shown
      to be as sensitive as the conventional tube complement-fixation inhibition test.

PMID- 4356472
TI  - Plaque assay for polyoma virus on primary mouse kidney cell cultures.
AB  - A plaque assay for polyoma virus using primary baby mouse kidney cells is
      reported.

PMID- 4356473
TI  - Serum from schizophrenic patients. Effect on cellular lactate stimulation and
      tryptophan uptake.

PMID- 4356474
TI  - Effect of vestibular and auditory stimulation on the REMs of REM sleep in
      autistic children.

PMID- 4356475
TI  - Depression, psychopathy, and herpesvirus type I antibodies. Lack of relationship.

PMID- 4356476
TI  - [Effect of denaturing agents on the parameters of EPR spectra of ceruloplasmin].

PMID- 4356477
TI  - [Thermal conformational transitions in electron-transporting biological
      membranes].

PMID- 4356478
TI  - [Energy metabolism and free-radical concentration in chick embryo and chick
      livers].

PMID- 4356479
TI  - Electron microscope observation of viruslike particles in comedocarcinoma of the
      human breast.

PMID- 4356480
TI  - Assessment of significance of proportions of intraductal and infiltrating tumor
      growth in ductal carcinoma of the breast.

PMID- 4356481
TI  - Light microscopic identification of the ribosome-lamella complex in "hairy cells"
      of leukemic reticuloendotheliosis.

PMID- 4356482
TI  - Ultimobranchial thyroid neoplasms in bulls. A syndrome resembling medullary
      thyroid carcinoma in man.

PMID- 4356484
TI  - A radiation-induced breast cancer.

PMID- 4356483
TI  - Mesenchymal chondrosarcoma. A study of the ultrastructure.

PMID- 4356485
TI  - Turnover of cholesteryl esters in plasma low-density and high-density
      lipoproteins in familial hyperbetalipoproteinaemia.

PMID- 4356486
TI  - [Hyperthermias due to neuroleptics. Attempted physiopathological interpretation].

PMID- 4356487
TI  - On the role of food vacuole formation in the uptake of dissolved nutrients by
      Tetrahymena.

PMID- 4356488
TI  - Two-dimensional electrophoresis of proteins of citric acid nuclei prepared with
      aid of a Tissumizer.

PMID- 4356490
TI  - Does the activation of succinate dehydrogenase affect the phosphorylating system
      in sub mitochondrial particles?

PMID- 4356489
TI  - Studies on the uptake and metabolism of adenosine 3':5'-cyclic monophosphate and
      N6,O2-dibutyryl 3':5'-cyclic adenosine monophosphate in sea urchin eggs.

PMID- 4356491
TI  - Constraints on the mechanism of reduction of molecular oxygen by cytochrome
      oxidase under coupled conditions.

PMID- 4356492
TI  - Quantitation of acid phosphatase and aryl sulphatase in rat hepatic parenchymal
      and kupffer cells.

PMID- 4356493
TI  - LH-RH stimulated gonadotropin release mediated by two distinct pituitary
      receptors.

PMID- 4356494
TI  - Mitochondrial protein synthesis and cyanide-resistant respiration in copper
      depleted, cytochrome oxidase-deficient Neurospora crassa.

PMID- 4356496
TI  - Changes in membrane function and chromatin template activity in diploid and
      transformed cells in culture.

PMID- 4356495
TI  - Aminopropyl glass and its p-phenylene diisothiocyanate derivative, a new support
      in solid-phase Edman degradation of peptides and proteins.

PMID- 4356497
TI  - [Virological aspects of tumor diseases in man].

PMID- 4356499
TI  - Relative efficiency of cell cultures for detection of viruses.

PMID- 4356498
TI  - Fatty acid composition of plasma lipoproteins in control subjects and in patients
      with malabsorption.
AB  - The fatty acid composition of cholesterol (cholesteryl) ester, triglyceride, and
      lecithin has been investigated in whole plasma and individual lipoproteins of
      healthy control subjects, of patients with malabsorption, and also of patients
      without malabsorption. The results show a decreased proportion of the essential
      fatty acid linoleic acid in all three lipid classes in both groups of patients as
      compared with the healthy controls. This abnormality was more marked in the
      malabsorbers, especially those with steatorrhoea secondary to intestinal
      resection. Unequivocal biochemical evidence of essential fatty acid deficiency,
      as indicated by the appearance of 5, 8, 11 eicosatrienoic acid in plasma
      lecithin, was observed in two patients, both of whom had undergone major
      intestinal resections. The results suggest that intestinal resection predisposes
      to the development of essential fatty acid deficiency.

PMID- 4356501
TI  - Rapid quantitative GLC analysis of digoxin.

PMID- 4356500
TI  - NMR spectroscopy: antibiotic interactions with phospholipids.

PMID- 4356502
TI  - Effect of addition of sodium salts to salicylic acid--cetrimide system.

PMID- 4356503
TI  - The phospholipid composition of human spermatozoa and seminal plasma.

PMID- 4356504
TI  - Renin release in anesthetized rats.

PMID- 4356505
TI  - Studies on the metabolism of aldosterone in chronic renal failure and anephric
      man.

PMID- 4356506
TI  - Dynamic studies of aldosterone in anephric man.

PMID- 4356508
TI  - [On the antidiuretic action of angiotensin II and of furosemide in a case of
      renal diabetes insipidus].

PMID- 4356507
TI  - [On various aspects of physiopathology of the renal tubule in childhood].

PMID- 4356509
TI  - [Pituitary adenoma in acromegaly-gigantism. Macroscopic, histological and
      ultrastructural study].

PMID- 4356510
TI  - [The sella turcica in acromegaly. Radiological study].

PMID- 4356511
TI  - [Surgical treatment of pituitary adenoma].

PMID- 4356512
TI  - [Rehabilitation in diseases of the peripheral nervous system (fitness for work in
      the industrialized conditions of our country)].

PMID- 4356513
TI  - [Transformation of lymphocytes of patients with multiple sclerosis, after
      treatment in vitro with phytoagglutinins].

PMID- 4356515
TI  - Congenital varicella-zoster infection related to maternal disease in early
      pregnancy.

PMID- 4356514
TI  - [Treatment with ACTH in the myasthenic syndrome with an immunological
      substratum].

PMID- 4356516
TI  - [Mesonephroid (or clear cell) tumors of the ovary. Clinico-anatomical study of 12
      cases].

PMID- 4356517
TI  - [Clinical and biological aspects of viral lung diseases].

PMID- 4356519
TI  - Effects of dibutyryl cyclic AMP on restoration of function of damaged sciatic
      nerve in rats.
AB  - In two experiments, the sciatic nerve of rats was either crushed or hemisected,
      and N(6),O(2)-dibutyryl adenosine 3',5'-monophosphate or saline was injected
      intramuscularly near the site of the lesion. In both types of nerve damage, the
      sensorimotor functions of animals treated with N(6),O(2)-dibutyryl adenosine
      3',5'-monophosphate returned earlier than did those of saline-treated control
      animals.

PMID- 4356518
TI  - Pentobarbital: selective depression of excitatory postsynaptic potentials.
AB  - The effects of pentobarbital (Nembutal) on synaptic transmission and postsynaptic
      potentials were studied by the use of several invertebrate preparations.
      Pentobarbital selectively and reversibly depressed both excitatory postsynaptic
      potentials and sodium-dependent postsynaptic responses to putative excitatory
      transmitters without affecting either inhibitory postsynaptic potentials or
      chloride- and potassium-dependent postsynaptic responses to putative
      transmitters. A selective depression of postsynaptic excitatory events was also
      observed with other central nervous system depressants (ethanol, chloroform,
      chloralose, diphenylhydantoin, and urethane). The results suggest that central
      and peripheral depression observed during general anesthesia is due to a
      selective depression of excitatory synaptic events.

PMID- 4356520
TI  - Hypertensive action of 18-hydroxydeoxycorticosterone.
AB  - 18-Hydroxydeoxycorticosterone is an adrenal steroid hormone causing salt and
      water retention and is secreted in greatly increased amounts in response to the
      pituitary hormone adrenocorticotropic hormone. Its production is abnormally high
      in some forms of hypertension in man and rat. Direct proof that 18
      hydroxydeoxycorticosterone is capable of causing hypertension is present. Daily
      subcutaneous injections of 200 micrograms, a low physiological dose,
      significantly increase the blood pressure of unilaterally nephrectomized saline
      treated rats after 2 weeks. This strengthens the hypothesis that 18
      hydroxydeoxycorticosterone contributes to the etiology of hypertension, possibly
      by a mechanism involving stressinduced release of adrenocorticotropic hormone.

PMID- 4356521
TI  - Treatment of acromegaly by stereotaxic cryohypophysectomy.

PMID- 4356523
TI  - Gonadal dysgenesis: the XY variant.

PMID- 4356522
TI  - Current concepts in diagnosis: electromyography in the diagnosis of neuromuscular
      disease.

PMID- 4356524
TI  - Amoebic liver abscess in eastern Uttar Pradesh, India.

PMID- 4356525
TI  - Polio and Coxsackievirus antibodies of New Guinean children.

PMID- 4356526
TI  - Effect of succinylcholine on single motor end-plates in man.

PMID- 4356527
TI  - A study of the invasive growth of malignant tumors. II. Ultrastructural features
      of the metastatic growth of Yoshida ascites hepatoma 7974 in the rat brain.

PMID- 4356528
TI  - Cell recognition and phagocytosis of SV40 transformed cell.

PMID- 4356529
TI  - Proposed standard methodology for the evaluation of silicosis hazards.

PMID- 4356530
TI  - Defective interfering viruses.

PMID- 4356531
TI  - The EB virus.

PMID- 4356532
TI  - Inhibition of gluconeogenesis in vitro by a metabolite of hypoglycin.

PMID- 4356533
TI  - The cyclic AMP receptor of Escherichia coli: immunological studies in extracts of
      Escherichia coli and other organisms.

PMID- 4356535
TI  - Stimulation by insulin of ornithine decarboxylase activity in cultured mammary
      tissue.

PMID- 4356534
TI  - Progesterone receptor associated with the "melanosome" fraction of Pleurodeles
      waltlii oocytes (Urodela amphibian).

PMID- 4356536
TI  - Isolation and characterization of fucose sulfate from jelly coat glycoprotein of
      sea urchin egg.

PMID- 4356537
TI  - The physical chemistry of hemes. II. Electron paramagnetic resonance study of the
      interaction of some iron(3)-porphyrins with fluoride ion in dimethylformamide.

PMID- 4356538
TI  - Adult rat brain synaptic vesicles. II. Lipid composition.

PMID- 4356539
TI  - Nuclear envelope isolation in peas.

PMID- 4356540
TI  - The asymmetric distribution of phospholipids in the human red cell membrane. A
      combined study using phospholipases and freeze-etch electron microscopy.

PMID- 4356541
TI  - A study on phospholipid exchange proteins present in the soluble fractions of
      beef liver and brain.

PMID- 4356542
TI  - Studies on the relationship between adenylate cyclase activity and calcium
      transport by cardiac sarcotubular membranes.

PMID- 4356543
TI  - DNA methylation in normal and tumour virus-transformed cells in tissue culture.
      I. The level of DNA methylation in BHK21 cells and in BHK21 cells transformed by
      polyoma virus (PyY cells).

PMID- 4356544
TI  - Antiviral activity of polynucleotides: poly(2'-fluoro-2'-deoxyuridylic acid).

PMID- 4356545
TI  - Increased incidence of lung metastases following treatment of rats bearing
      hepatomas with irradiated tumour cells and the benefical effect of
      Corynebacterium parvum in this system.

PMID- 4356546
TI  - Radioimmunoassay of melanocytes-stimulating hormone (beta-MSH) in human plasma.

PMID- 4356547
TI  - [Chromosomal study of 20 embryonic tumors after short term culture].

PMID- 4356548
TI  - Catecholamines in invertebrates.

PMID- 4356549
TI  - Catecholamine uptake processes.

PMID- 4356550
TI  - Prostaglandins at adrenergic nerve-endings.

PMID- 4356552
TI  - Dopamine in the basal ganglia. Its role and therapeutic implications (including
      the clinical use of L-DOPA).

PMID- 4356553
TI  - Editorial: Spread of colds.

PMID- 4356551
TI  - The mechanisms of action of some antihypertensive drugs.

PMID- 4356554
TI  - An efficient ultrafiltration method for enterovirus recovery from ground beef.

PMID- 4356555
TI  - Purification of Clostridium perfringens type C theta toxin.

PMID- 4356557
TI  - Electron microscopic studies on the trabecular meshwork in two cases of
      corticosteroid-glaucoma.

PMID- 4356556
TI  - Biosynthesis of thiamine by Phycomyces blakesleeanus.

PMID- 4356558
TI  - Tumour-associated antigen in the serum of rats with large Rous sarcoma virus
      induced tumours.

PMID- 4356559
TI  - Growth in spinner culture of AKR mouse cells, the K3b, induced by the Schmidt
      Ruppin strain of Rous sarcoma virus.

PMID- 4356561
TI  - Effects of L-DOPA on natural night sleep and on rebound of REM sleep.

PMID- 4356562
TI  - Time relationship between the lateral geniculate nucleus activity and eye
      movement in the unanesthetized and reserpinized cat.

PMID- 4356560
TI  - Failure of Bacillus Calmette-Guerin (BCG) infection to suppress the growth of
      transplanted mouse and rat sarcomas.

PMID- 4356564
TI  - Presence of fast moving type IV hexokinase isozyme in Morris hepatoma.

PMID- 4356563
TI  - Synergistic effect of fusidic acid with polymyxin-B and amphotericin-B on
      transformed and normal fibroblastic cells.

PMID- 4356566
TI  - Carcinostatic effect of 1,1'-polymethylenebis-(1-nitrosourea) on AH-13 and L-1210
      cells.

PMID- 4356565
TI  - Measurement of estrogen-binding capacity in the hormone-dependent and  
      independent rat mammary tumors.

PMID- 4356567
TI  - A serological survey of adenovirus infection in Pondicherry.

PMID- 4356568
TI  - The polymerization of actin: its role in the generation of the acrosomal process
      of certain echinoderm sperm.
AB  - When Asterias or Thyone sperm come in contact with egg jelly, a long process
      which in Thyone measures up to 90 microm in length is formed from the acrosomal
      region. This process can be generated in less than 30 s. Within this process is a
      bundle of microfilaments. Water extracts prepared from acetone powders of
      Asterias sperm contain a protein which binds rabbit skeletal muscle myosin
      forming a complex whose viscosity is reduced by ATP. Within this extract is a
      protein with the same molecular weight as muscle actin. It can be purified either
      by collecting the pellet produced after the addition of Mg(++) or by reextracting
      an acetone powder of actomyosin prepared by the addition of highly purified
      muscle myosin to the extract. The sperm actin can be polymerized and by electron
      microscopy the polymer is indistinguishable from muscle F-actin. The sperm actin
      was shown to be localized in the microfilaments in the acrosomal processes by:
      (a) heavy meromyosin binding in situ, (b) sodium dodecyl sulfate (SDS) gel
      electrophoresis of the isolated acrosomal processes and a comparison to gels of
      flagella which contain no band corresponding to the molecular weight of actin,
      and (c) SDS gel electrophoresis of the extract from isolated acrosomal caps.
      Since the precursor for the microfilaments in the unreacted sperm appears
      amorphous, we suspected that the force for the generation of the acrosomal
      process is brought about by the polymerization of the sperm actin. This
      supposition was confirmed, for when unreacted sperm were lysed with the detergent
      Triton X-100 and the state of the actin in the sperm extract was analyzed by
      centrifugation, we determined that at least 80% of the actin in the unreacted
      sperm was in the monomeric state.

PMID- 4356570
TI  - Microfilaments in the polar lobe constriction of fertilized eggs of Ilyanassa
      obsoleta.

PMID- 4356569
TI  - Subplasmalemmal microfilaments and microtubules in resting and phagocytizing
      cultivated macrophages.
AB  - The subplasmalemmal organization of the free and glass-attached surfaces of
      resting and phagocytizing cultivated macrophages were examined in an attempt to
      define specific membrane-associated structures related to phagocytosis. From
      analysis of serial thin sections of oriented cells it was found that the
      subplasmalemmal region of the attached cell surface has a complex microfilament
      and microtubule organization relative to the subplasmalemmal area of the free
      surface. A filamentous network composed of 40-50-A microfilaments extended for a
      depth of 400-600 A from the attached plasma membrane. Immediately subjacent to
      the filamentous network was a zone of oriented bundles of 40-50-A microfilaments
      and a zone of microtubules. Additional microtubules were found to extend from the
      plasma membrane to the interior of the cell in close association with electron
      dense, channellike structures. In contrast, the free aspect of the cultivated
      macrophage contained only the subplasmalemmal filamentous network. However, after
      a phagocytic pulse with polystyrene particles (14 microm diam) microtubules and
      oriented filaments similar to those found on the attached surface were observed
      surrounding the ingested particles. The observations reported in this paper
      provide support for the hypothesis that microfilaments and/or microtubules play a
      role in the translocation of plasma membrane required for the functionally
      similar processes of phagocytosis and cell attachment to glass.

PMID- 4356571
TI  - Golgi fractions prepared from rat liver homogenates. I. Isolation procedure and
      morphological characterization.
AB  - In devising a new procedure for the isolation of Golgi fractions from rat liver
      homogenates, we have taken advantage of the overloading with very low density
      lipoprotein (VLDL) particles that occurs in the Golgi elements of hepatocytes
      approximately 90 min after ethanol is administered (0.6 g/100 g body weight) by
      stomach tube to the animals. The VLDLs act as morphological markers as well as
      density modifiers of these elements. The starting preparation is a total
      microsomal fraction prepared from liver homogenized (1:5) in 0.25 M sucrose. This
      fraction is resuspended in 1.15 M sucrose and loaded at the bottom of a
      discontinuous sucrose density gradient. Centrifugation at approximately 13 x
      10(6)g.min yields by flotation three Golgi fractions of density >1.041 and
      <1.173. The light and intermediate fractions consist essentially of VLDL-loaded
      Golgi vacuoles and cisternae. Nearly empty, often collapsed, Golgi cisternae are
      the main component of the heavy fraction. A procedure which subjects the Golgi
      fractions to hypotonic shock and shearing in a French press at pH 8.5 allows the
      extraction of the content of the Golgi elements and the subsequent isolation of
      their membranes by differential centrifugation.

PMID- 4356573
TI  - New membrane formation during cytokinesis in normal and cytochalasin B-treated
      eggs of Xenopus laevis. I. Electron microscope observations.
AB  - A method is described for measuring and calculating the preexisting surface in
      uncleaved Xenopus eggs and the rate of surface growth in cleaving eggs. Surface
      marking experiments with cytochalasin B-treated eggs show that the unpigmented
      surface grows by de novo formation and not by expansion of preexisting pigmented
      surface. The onset of new surface formation during first cleavage was studied by
      using transmission electron microscope and scanning electron microscope
      techniques. At 3-4 min and at 7-8 min after the onset of cleavage the eggs were
      fixed in the presence of ruthenium red (RR). Evidence is presented that
      unpigmented surface representing new membrane comes into appearance between four
      and eight min. This surface has a selective binding capacity for RR.
      Concomitantly with the appearance of new membrane, endoplasmic reticulum (ER)
      cisternae are in continuity with, and dense cytoplasmic inclusions coalesce with,
      the membrane along the furrow. The latter give rise to liposome-like bodies. The
      possibility is discussed that the ER cisternae transport a surface exudate (a
      carbohydrate complex), that the dense cytoplasmic inclusions represent pools of
      membrane precursor, and that membranogenesis takes place by direct insertion of
      pooled precursors into the cell surface. In a second paper, these findings will
      be correlated with electrophysiological measurements.

PMID- 4356574
TI  - The isolation of enteroviruses from cases of acute conjunctivitis.
AB  - In two epidemics of acute enterovirus conjunctivitis the diagnosis could only be
      established by the use of human embryonic organ cultures. In one instance
      cultures of ciliated respiratory epithelium proved sensitive to the virus but
      similar culture failed to support growth of the virus from the second outbreak
      which was isolated in organ cultures of conjunctiva. The virus associated with a
      third outbreak had previously been isolated from the original material by culture
      in human embryo kidney cells, but it required passage in organ culture for its
      detection after the specimens had been diluted.

PMID- 4356572
TI  - Golgi fractions prepared from rat liver homogenates. II. Biochemical
      characterization.
AB  - The three Golgi fractions isolated from rat liver homogenates by the procedure
      given in the companion paper account for 6-7% of the protein of the total
      microsomal fraction used as starting preparation. The lightest, most homogeneous
      Golgi fraction (GF(1)) lacks typical "microsomal" activities, e.g., glucose-6
      phosphatase, NADPH-cytochrome c-reductase, and cytochrome P-450. The heaviest,
      most heterogeneous fraction (GF(3)) is contaminated by endoplasmic reticulum
      membranes to the extent of approximately 15% of its protein. The three fractions
      taken together account for nearly all the UDP-galactose: N-acetyl-glucosamine
      galactosyltransferase of the parent microsomal fraction, and for approximately
      70% of the activity of the original homogenate. Omission of the ethanol treatment
      of the animals reduces the recovery by half. The transferase activity is
      associated with the membranes of the Golgi elements, not with their content.
      Galactose is transferred not only to N-acetyl-glucosamine but also to an
      unidentified lipid-soluble component.

PMID- 4356575
TI  - Binding of spin-labeled local anesthetics to lobster nerves.

PMID- 4356577
TI  - Acute submonary oil embolism and lethal dose study of an oily contrast medium
      following portal vein administration into dogs.

PMID- 4356576
TI  - A study of the ultrastructural organization of cytochrome c-phospholipid
      membranes as revealed by various experimental treatments.

PMID- 4356578
TI  - Release of acetylcholine from perfused cerebral ventricles in unanaesthetized
      dogs during waking and sleep.

PMID- 4356579
TI  - Chemico-biological relationships of follicle stimulating hormone-releasing
      hormone and luteinizing hormone-releasing hormone.

PMID- 4356581
TI  - Gel filtration and preparative free isoelectric focusing of rabbit serum
      phosphorylphosphatase.

PMID- 4356582
TI  - [Editorial: Viruses and breast cancers].

PMID- 4356580
TI  - Adenosine 3',5' cyclic monophosphate in Euglena gracilis.

PMID- 4356583
TI  - [Granulosa and thecal tumors of the ovary].

PMID- 4356584
TI  - Effect of oxidation on chemical spectral and immunochemical properties of egg
      yolk lipoprotein.

PMID- 4356586
TI  - [Anomalous unstable hemoglobins, a special group of hereditary hemolytic anemias
      (survey of the literature and the authors' own data].

PMID- 4356585
TI  - Growth and development in adolescence.

PMID- 4356587
TI  - Developing a multiphasic rehabilitation program for psychotic patients in a
      community mental health clinic.

PMID- 4356588
TI  - The molecular and ionic basis of altered myocardial contractility.

PMID- 4356589
TI  - Biliary lipid composition in normalipidemic and prebeta hyperlipoproteinemic
      gallstone patients. Influence of sucrose feeding of the patients on the biliary
      lipid composition.

PMID- 4356591
TI  - [Gene activation and mRNA synthesis in higher organisms].

PMID- 4356590
TI  - [Clinical physiopathology of certain forms of secondary arterial hypertension].

PMID- 4356592
TI  - [Treatment of malignant exophthalmos with beta-1-24 corticotropin].

PMID- 4356593
TI  - [The paraneoplastic neuromyopathies (author's transl)].

PMID- 4356594
TI  - [Adrenal gland scanning with 131I-19-iodocholesterol (author's transl)].

PMID- 4356595
TI  - [The clinical application of a chromatographic semiquantitative method for the
      determination of the vitamin-D level in blood (author's transl)].

PMID- 4356597
TI  - Effect of tricyclic antidepressants on phosphodiesterase. Correlation between
      aggregability and thrombocyte metabolism.

PMID- 4356596
TI  - The effect of psychotropic drugs on phosphodiesterase cAMP, ATPase and on
      5'nucleotidase.

PMID- 4356598
TI  - The effect of 10 days' pyrithioxine administration on sleep cycles in rats.

PMID- 4356599
TI  - [A new type of inclusion in the ergastoplasm of peripheral lymphocytes during
      virus infection].

PMID- 4356600
TI  - Adenofibrosis in the rat liver, with persistence of polychlorinated biphenyls in
      adipose tissue.

PMID- 4356601
TI  - Histiocytosis X histogenetic arguments for a Langerhans cell origin.

PMID- 4356602
TI  - Transport of methotrexate into normal haemopoietic cells and into leukaemic cells
      and its effects on DNA synthesis.

PMID- 4356603
TI  - Proceedings: phosphate compounds as bone-scanning agents.

PMID- 4356604
TI  - Proceedings: the influence of transplantable tumours on the healing of colonic
      anastomoses in the rat.

PMID- 4356605
TI  - Proceedings: controlled trial of wound spraying with poly-antibiotic or povidone
      iodine aerosols.

PMID- 4356606
TI  - Transfer factor induced delayed hypersensitivity in X-linked combined
      immunodeficiency.

PMID- 4356608
TI  - Mechanism of renal handling of angiotensin II in the dog.

PMID- 4356607
TI  - Prostaglandins and the kidney.

PMID- 4356610
TI  - Hypertrophy of the ACTH-producing cell following adrenalectomy: a quantitative
      electron microscopic study.

PMID- 4356609
TI  - Altered ion transport in vascular smooth muscle from spontaneously hypertensive
      rats. Influences of aldosterone, norepinephrine, and angiotensin.

PMID- 4356611
TI  - ACTH and cAMP stimulation of adrenal ribosomal protein phosphorylation.

PMID- 4356612
TI  - Cardiac glucocorticoid receptors: the binding of tritiated dexamethasone in rat
      and dog heart.

PMID- 4356613
TI  - Evidence for separate sites of action for the antilipolytic effects of insulin
      and prostaglandin E1.

PMID- 4356614
TI  - Analytical and confirmative techniques for dibenzo-p-dioxins based upon their
      cation radicals.

PMID- 4356615
TI  - Identification of herpes simplex and vaccinia viruses in corneal cell cultures
      with immunoperoxidase: a light and electron microscopic study.

PMID- 4356616
TI  - Kinetics of phosphate incorporation into adenosine triphosphate and guanosine
      triphosphate in bacteria.
AB  - Escherichia coli cells were labeled with (33)PO(4) for several generations and
      then (32)PO(4) was added, samples were taken at various times, and adenosine
      triphosphate (ATP) and guanosine triphosphate (GTP) were purified from an acid
      extract. The ratio of (32)P/(33)P in each of the six phosphate species was
      determined and compared to the ratio expected at isotopic steady state. The rate
      constants of the simplest network of pools which could explain the data, and were
      consistent with metabolic pathways, were then calculated. In the range of times
      studied (30 to 3,000 s at 21.5 C) the following generalizations can be made. (i)
      The gamma-phosphate at ATP requires 2,200 s to achieve 50% of its final specific
      activity and behaves as if it were exchanging with another species 4.4 times as
      large, with this other species turning over in 540 s. (ii) The beta-phosphate of
      ATP and the gamma-phosphate of GTP are in equilibrium with the gamma-phosphate of
      ATP. (iii) The specific activity of the gamma-phosphate of GTP lags 66 s behind
      the gamma-phosphate of ATP. (iv) The alpha-phosphates of ATP and GTP have equal
      specific activities which lag far behind the other four phosphates. A single
      precursor pool with a turnover time of 416s fits the data best, although a fair
      fit can be obtained assuming several sequential precursor pools with much shorter
      turnover times. These findings are consistent with known biosynthetic pathways
      and the probable flows through them, including the relationship of nucleotide
      biosynthesis to ribonucleic acid synthesis and turnover.

PMID- 4356617
TI  - Action of ribonuclease T1 on 30S ribosomes of Escherichia coli and its role in
      sequence studies on 16S ribonucleic acid.
AB  - Two large ribonucleic acid (RNA) fragments have been obtained from T1-RNase
      treated 30S ribosomes of Escherichia coli. One fragment, about 475 nucleotides
      long, contains all the unique oligonucleotides found by Fellner and associates in
      sections of 16S RNA designated P, E, E', and K, and one-half the large
      oligonucleotides of section A. The other large fragment is about 300 nucleotides
      long and contains the oligonucleotides found in sections C, C', C''. The
      isolation of these large fragments seems to confirm the arrangement of sections
      within 16S RNA. There are also recovered from nuclease-treated ribosomes three
      small fragments, one (120 nucleotides long) from the 5' end, one (26 nucleotides
      long) from the 3' OH end of the chain, and another section (66 nucleotides long)
      from the middle of the 16S RNA chain. Small molecular weight material is also
      generated by nuclease treatment, and about half this material is derived from a
      region close to the 3' OH end of the 16S RNA chain. This indicates that the most
      accessible part of the rRNA of E. coli 30S ribosomes is a region 100 to 150
      nucleotides long near the 3' end of the chain. A general scheme is proposed to
      explain the generation of the various-sized RNA products from the rRNA of the 30S
      ribosome.

PMID- 4356618
TI  - Studies on isopentenyl pyrophosphate isomerase with artificial substrates.

PMID- 4356620
TI  - Properties of modified cytochromes. II. Ligand binding to reduced carboxymethyl
      cytochrome c.

PMID- 4356619
TI  - The appearance of transient species of cytochrome c upon rapid oxidation or
      reduction at alkaline pH.

PMID- 4356621
TI  - The substrate and anomeric specificity of fructokinase.

PMID- 4356623
TI  - Lecithin: cholesterol acyltransferase of human plasma. Role of chylomicrons, very
      low, and high density lipoproteins in the reaction.

PMID- 4356622
TI  - Modification of sialyl residues of sialoglycoprotein(s) of the human erythrocyte
      surface.

PMID- 4356624
TI  - Mitochondrial functions in an ethanol-induced fatty liver.

PMID- 4356625
TI  - Regulation of endogenous phosphorylation of specific proteins in synaptic
      membrane fractions from rat brain by adenosine 3':5'-monophosphate.

PMID- 4356627
TI  - Invasive pleomorphic adenoma of hard palate.

PMID- 4356626
TI  - The cryosurgical treatment of glomus jugulare tumours.

PMID- 4356628
TI  - Internal maxillary artery ligation for the removal of juvenile nasopharyngeal
      angiofibroma.

PMID- 4356629
TI  - Effects of early postnatal dietary protein restriction and repletion on porcine
      muscle growth and composition.

PMID- 4356630
TI  - Lead-induced inclusion bodies. Solubility, amino acid content, and relationship
      to residual acidic nuclear proteins.

PMID- 4356632
TI  - Effect of phenobarbital and 3-methylcholanthrene pretreatment on the
      hepatotoxicity of 1,1,1-trichloroethane and 1,1,2-trichloroethane.

PMID- 4356631
TI  - Ultrastructure of sulfatide storage in normal and sulfatase-deficient fibroblasts
      in vitro.

PMID- 4356633
TI  - Tracheal soft tissue mass. Case reports.

PMID- 4356634
TI  - Prevalence of oropharyngeal excreters of leukocyte-transforming agents among a
      human population.

PMID- 4356635
TI  - Epidemic keratoconjunctivitis. A severe industrial outbreak due to adenovirus
      type 8.

PMID- 4356636
TI  - Acid-base balance of cisternal and lumbar cerebrospinal fluid in hospital
      patients.

PMID- 4356637
TI  - Persistence of poliovirus neutralizing antibodies eight years after immunization
      with live, attenuated-virus vaccine.

PMID- 4356639
TI  - Editorial: Treatment of oat-celled carcinoma of the bronchus.

PMID- 4356638
TI  - Editorial: Epidemic keratoconjunctivitis and hand washing.

PMID- 4356641
TI  - Pituitary-gonadal relations in female children and adolescents.

PMID- 4356640
TI  - [Nervous tissue tumors and current technics of morphological and etiopathogenic
      studies].

PMID- 4356642
TI  - Response to 2-deoxy-D-glucose and to glucagon in "ketotic hypoglycemia" of
      childhood: evidence for epinephrine deficiency and altered alanine availability.

PMID- 4356643
TI  - Intestinal mucosa of dogs with ileocystoplasties. Long-term histologic and
      histochemical changes.

PMID- 4356644
TI  - The metabolism of benomyl fungicide in mammals.

PMID- 4356645
TI  - Carcinoma of the rectum in old age.

PMID- 4356647
TI  - Isolation of rat liver plasma membranes by zonal centrifugation: increased yield
      with Ca2+.

PMID- 4356646
TI  - Recurrent control from motor axon collaterals of Ia inhibitory pathways in the
      spinal cord of the cat.

PMID- 4356649
TI  - Separation of cyclic 3',5'-AMP from ATP, ADP, and 5'-AMP by precipitation with
      inorganic compounds.

PMID- 4356648
TI  - Synthesis of isotopically labeled delta2-isopentenylpyrophosphate.

PMID- 4356650
TI  - A specific micromethod for determination of acetyl residues in proteins.

PMID- 4356651
TI  - The temperature dependence of the spectroscopic properties of reduced
      nicotinamide adenine dinucleotide.

PMID- 4356652
TI  - A quick and specific assay for hydroxyproline.

PMID- 4356653
TI  - Quantitative determination of reducing sugars, oligosaccharides, and
      glycoproteins with (3H)borohydride.

PMID- 4356654
TI  - [Value of duodenoscopy with papilla catheterization in hepato-biliary and
      pancreatic diseases (apropos of 400 examinations)].

PMID- 4356655
TI  - [Morphological aspect of Australia antigen during B virus hepatitis].

PMID- 4356656
TI  - Isotopic evidence for futile cycles in liver cells.

PMID- 4356657
TI  - Relationship between isotopic reversibility and futile cycles in isolated rat
      liver parenchymal cells.

PMID- 4356658
TI  - Glycogen phosphorylase kinase deficiency: a survey of enzymes in phosphorylase
      activating system.

PMID- 4356659
TI  - On the role of a cuprous ion intermediate in the galactose oxidase reaction.

PMID- 4356660
TI  - Development of the cardiac beta adrenergic receptor in fetal rat heart.

PMID- 4356661
TI  - The stereospecificity of hydrogen abstraction by uridine diphosphoglucose
      dehydrogenase.

PMID- 4356662
TI  - Subcellular distribution of methylmalonyl CoA carbonylmutase in human liver
      extracts.

PMID- 4356663
TI  - The purification and assay of the prostatic antibacterial factor (PAF).

PMID- 4356664
TI  - Energy metabolism in washed human platelets responsive to ADP: comparison with
      platelets in plasma.

PMID- 4356666
TI  - Renal vascular resistance and aortic pressure as determinants of sodium
      reabsorption.

PMID- 4356665
TI  - Effect of repeated treatment of rabbit platelets with low concentrations of
      thrombin on their function, metabolism and survival.

PMID- 4356667
TI  - Application of drug-receptor theories to angiotensin.

PMID- 4356669
TI  - Increased renin activity after cold storage of human plasma.

PMID- 4356668
TI  - Cytochrome oxidase of skeletal muscle: adaptive response to chronic disuse.

PMID- 4356670
TI  - Effects of anions on frog ventricle.

PMID- 4356672
TI  - [Effect of 3',5'-cyclic AMP on NAD-kinase activity in retinal outer segments].

PMID- 4356671
TI  - The effects of thyroxine and isopropylnoradrenaline on cytochrome oxidase
      activity in brown adipose tissue.

PMID- 4356673
TI  - Effects of ACTH on melanophores and iridophores isolated from bullfrog tadpoles.

PMID- 4356676
TI  - Isolation and characterization of revertant cell lines. IV. Direct selection of
      serum-revertant sublines of SV40-transformed 3T3 mouse cells.

PMID- 4356675
TI  - Isolation and characterization of revertant cell lines. 3. Isolation of density
      revertants of SV40-transformed 3T3 cells using colchicine.

PMID- 4356674
TI  - The role of macrophages in the cytotoxic killing of tumour cells in vitro. I.
      Primary immunization of lymphocytes in vitro for target cell killing and the
      mechanism of lymphocyte-macrophage cooperation.

PMID- 4356677
TI  - pH, serum and Zn++ in the regulation of DNA synthesis in cultures of chick embryo
      cells.

PMID- 4356679
TI  - Inhibition of marrow granulocytic colony formation by phytohemagglutinin.

PMID- 4356678
TI  - Uridine uptake and its intracellular phosphorylation during the cell cycle.

PMID- 4356680
TI  - Improved sensitivity in the measurement of estrogen receptor in human breast
      cancer.

PMID- 4356681
TI  - Persistent infection of mouse cells with Sindbis virus: role of virulence of
      strains, auto-interfering particles and interferon.

PMID- 4356683
TI  - The effect of ethidium bromide on L cells and encephalomyocarditis virus
      replication.

PMID- 4356682
TI  - Replication of rhinovirus RNA.

PMID- 4356684
TI  - Effect of various inhibitors on the expression of polyoma virus-induced surface
      antigen in BHK21 cells.

PMID- 4356685
TI  - Circulating interferon in rabbits after administration of human interferon by
      different routes.

PMID- 4356687
TI  - The mechanism of interferon action in single cells: accumulation of intracellular
      virus.

PMID- 4356686
TI  - Effect of interferon on virus production from isolated single cells.

PMID- 4356688
TI  - Genetic and structural implications of tryptic peptide analysis of poliovirus
      structural protein.

PMID- 4356689
TI  - Structural proteins of foot-and-mouth disease virus.

PMID- 4356690
TI  - Inactivation of myxoviruses by lymphoid cells.

PMID- 4356691
TI  - Growth and antigenic characteristics of subclones of hamster cells transformed by
      the Schmidt-Ruppin strain of Rous sarcoma virus.

PMID- 4356692
TI  - Adenohypophysis: ultrastructural cytochemistry. A review.

PMID- 4356693
TI  - Relief of massive splenomegaly after irradiation of liver involved by Wilms'
      tumor.

PMID- 4356694
TI  - Vitamin C and chronologic versus bone age.

PMID- 4356696
TI  - Electron microscopic studies on various types of inclusions found in autopsy
      cases. II. Spironolactone inclusion body in autopsy cases and its experimental
      studies on rhesus monkey.

PMID- 4356695
TI  - A granular cell myoblastoma on the ventral surface of the tongue: a case report.

PMID- 4356697
TI  - Cultures of renal biopsies: outgrowth of vacuolated and multinucleated cells.

PMID- 4356698
TI  - Plasma renin activity in segmental hypoplasia of the kidneys with hypertension.

PMID- 4356699
TI  - [Clinical adenohypophyseal patterns of TSH and ACTH of hypothalamic origin].

PMID- 4356700
TI  - [Waldenstrom's macroglobulinemia in the lymphoid follicle of the palatine
      amygdala. Ultrastructural study of 3 cases].

PMID- 4356702
TI  - [Diabetes and hemochromatosis. II. Diabetes of idiopathic hemochromatosis and
      common diabetes. Apropos of 130 personal cases of hemochromatosis].

PMID- 4356701
TI  - [Diabetes and hemochromatosis. I. Diabetes in idiopathic hemochromatosis. Apropos
      of 130 personal cases of hemochromatosis].

PMID- 4356703
TI  - [Characteristics of acute meningitis in aged patients].

PMID- 4356704
TI  - [Digestive hemorrhages caused by drugs].

PMID- 4356705
TI  - [Treatment and surveillance of severe chronic respiratory insufficiency].

PMID- 4356706
TI  - [Hemangioendothelial sarcoma of the peritoneum revealed by an apparently
      spontaneous rupture of the spleen].

PMID- 4356707
TI  - [Vitamin D, rickets, and vitamin D-resistant rickets].

PMID- 4356708
TI  - Prolongation of allograft survival in mice by inducers of interferon.

PMID- 4356709
TI  - Enhancement of the dye-exclusion cytotoxic test by insulin and inhibition by
      cyclic adenosine 3:5-monophosphate and theophylline.

PMID- 4356710
TI  - Herpesviruses in renal transplant patients.

PMID- 4356711
TI  - Some aspects of food and nutrition in Sierra Leone.

PMID- 4356712
TI  - [Investigations on the role of cyclic 3',5'-AMP and active sodium transport in
      gerneration of action potential in vivo (author's transl)].

PMID- 4356715
TI  - Clinical spectrum of infection due to Bacillus species.

PMID- 4356714
TI  - Multisystem involvement in chronic liver disease. Studies on the incidence and
      pathogenesis.

PMID- 4356716
TI  - [Relation between radiation dose, formation of free radicals and creation of
      chromosome aberrations in lymphocytes].

PMID- 4356717
TI  - Electromyographic and mechanical effects of suxamethonium and tubocurarine on
      twitch, tetanic and post-tetanic responses.

PMID- 4356718
TI  - Disseminated perforating granuloma annulare.

PMID- 4356719
TI  - Tissue interrelationships in cutaneous granuloma.

PMID- 4356720
TI  - Heterologous protein-RNA interactions in bacterial ribosomes.

PMID- 4356722
TI  - Effect of acetaldehyde on activity of shuttles for the transport of reducing
      equivalents into the mitochondria.

PMID- 4356721
TI  - On the properties of a membrane-associated protein kinase from Chinese hamster
      ovary cells.

PMID- 4356723
TI  - Regulation of cholesterol synthesis in normal and malignant tissue.

PMID- 4356724
TI  - Gastropod nervous system as a model experimental system in neurobiological
      research.

PMID- 4356725
TI  - [Cyclic nucleotides in cellular activity].

PMID- 4356727
TI  - The state pharmacy's role in an aftercare program.

PMID- 4356726
TI  - [Sanitary virological characteristics of the sewage from some municipal sewer
      systems of the Uzbek SSR].

PMID- 4356728
TI  - Giant islet cell tumor of the pancreas with alpha-like granules. An
      ultrastructural study.

PMID- 4356730
TI  - Effect of acute neurogenic stress on hypothalamic corticotropin-releasing factor
      content.

PMID- 4356729
TI  - Burkitt's lymphoma in an Israeli child.

PMID- 4356731
TI  - Intracranial reticulum cell sarcoma associated with immunoglobulin A deficiency.
AB  - A case is reported of a 46 year old woman who died after a five month illness
      characterized by focal neurological signs, evidence of meningeal irritation, and
      the finding of 'blast' cells in the CSF. Immunoglobulin A was consistently absent
      from her serum and secretions. Necropsy showed extensive infiltration by a
      reticulum-cell sarcoma of the subarachnoid space, with tumour nodules on several
      cranial nerves and tumour infiltration of the tuber cinereum. The significance of
      the association between immunoglobulin A deficiency and neoplasia is discussed.

PMID- 4356732
TI  - Absence of nystagmus during REM sleep in a patient with waking nystagmus and
      oscillopsia.
AB  - Polygraphic recording is presented of the sleep pattern in a young male who
      developed nystagmus and oscillopsia associated with a remittent CNS demyelinating
      disease. The vestibular nystagmus observed during wakefulness disappeared during
      all stages of sleep, including rapid eye movement sleep (REM). Since vestibular
      nystagmus experimentally induced in wakefulness is also absent during all phases
      of sleep, these findings suggest that during sleep similar suppressive mechanisms
      are operative.

PMID- 4356734
TI  - Cell culture contaminants.

PMID- 4356733
TI  - Ectopic pinealoma: an unusual clinical presentation and a histochemical
      comparison with a seminoma of the testis.
AB  - A patient with ectopic pinealoma first presented with apparent anorexia nervosa
      and hypernatraemic coma. A history of diabetes insipidus two months previously
      was not known on admission to hospital. The diabetes insipidus was unmasked by
      the administration of steroids. Neuroendocrinal and neuropathological aspects of
      the case are discussed with reference to the march of symptoms due to the growth
      of the tumour. Histochemical evidence is presented supporting the similarity
      between ectopic pinealoma and seminoma which suggests that they may more properly
      be referred to as atypical teratomas.

PMID- 4356735
TI  - Basic principles of a method of nucleoli isolation.

PMID- 4356736
TI  - A technique for studying chemotaxis of leukocytes in well-defined chemotactic
      fields.

PMID- 4356737
TI  - [On some aspects of renal tubule physiopathology in childhood].

PMID- 4356739
TI  - The isolation and survival characterization of radiation and chemical-mutagen
      sensitive mutants of Pseudomonas aeruginosa.

PMID- 4356738
TI  - Divergent action mechanism of cAMP and dibutyryl cAMP on cell proliferation and
      macromolecular synthesis in HeLa S3 cultures.

PMID- 4356741
TI  - Mutagen sensitivity of Drosophila melanogaster. I. Isolation and preliminary
      characterization of a methyl methanesulphonate-sensitive strain.

PMID- 4356740
TI  - Molecular specificity of 2-aminopurine in Saccharomyces cerevisiae.

PMID- 4356742
TI  - The nature of reverse mutations in Drosophila melanogaster.

PMID- 4356743
TI  - Enhancement by caffeine of N-methyl-N-nitrosourea-induced mutations and
      chromosome aberrations in Chinese hamster cells.

PMID- 4356744
TI  - Induced discontinuous lesions in the X-chromosome of Drosophila.

PMID- 4356745
TI  - DNA repair capacity and susceptibility to chromosome breakage in xeroderma
      pigmentosum cells.

PMID- 4356746
TI  - Absence of Epstein-Barr viral DNA in Amercian Burkitt's lymphoma.

PMID- 4356748
TI  - [Methods of evaluation of the degree of maturity of the newborn].

PMID- 4356749
TI  - [So-called rickets-like diseases in children].

PMID- 4356751
TI  - [Malignant mediastinal tumors of neurogenic origin in children].

PMID- 4356750
TI  - A polyoma-induced hamster tumor cell with altered DNA synthesis in vivo and
      reduced polynucleotide ligase activity in vitro.

PMID- 4356752
TI  - [Use of emulsified lipiodol ultrafluide in indirect lymphography].

PMID- 4356753
TI  - Influence of chlorine dioxide water treatment on numbers of bacteria associated
      with processed turkey.

PMID- 4356754
TI  - Relative concentration and plasma content of yolk lipoprotein precursor in three
      lines of turkeys.

PMID- 4356755
TI  - [Early diagnosis and mediastinal metastasizing of bronchial carcinoma].

PMID- 4356756
TI  - [Leucine test in the diagnosis of insulinomas].

PMID- 4356757
TI  - In vitro studies of human tumor and embryonic tissue.

PMID- 4356758
TI  - [Extracellular cyclic nucleotides: occurrence, analysis and diagnostic
      significance (author's transl)].

PMID- 4356759
TI  - [Determination of urinary testosterone in man: a comparison between two methods
      using gas phase chromatography and competitive protein binding analysis
      respectively (author's transl)].

PMID- 4356761
TI  - The effect of LPF (leukocytosis promoting factor) on the kinetics of colony
      forming cells.

PMID- 4356762
TI  - The lysosomal system in lymphocytes--from cyclic AMP to gene activation.

PMID- 4356760
TI  - Cytologic aspects of abortive transformation in the polyoma virus-hamster cell
      system.

PMID- 4356763
TI  - Ultrastructure and cytochemistry of the synapse: isolation and nature of
      receptors in the central nervous system.

PMID- 4356764
TI  - The types and sites of cholinergic receptors.

PMID- 4356766
TI  - Biochemistry of synaptic plasticity studied in single neurons.

PMID- 4356765
TI  - Effects of drugs on inhibitory synapses.

PMID- 4356768
TI  - Aggregation of human blood platelets by unrelated antigen-antibody reaction:
      sequence of reaction and role of complement.

PMID- 4356769
TI  - Thyroid iodine metabolism in vitro. I. Experimental technique.

PMID- 4356767
TI  - Cyclic adenosine 3',5'-monophosphate and estrogenic stimulation of uterine
      metabolism.

PMID- 4356770
TI  - [Immunodepressors in ophthalmology].

PMID- 4356771
TI  - Experimental infection with mouse adenovirus in adult mice.

PMID- 4356773
TI  - Inhibition of hog cholera virus by acriflavine. A property shared with bovine
      virus diarrhoea virus. Brief report.

PMID- 4356772
TI  - DNA-dependent DNA polymerase pattern in noninfected and herpesvirus infected
      rabbit kidney cells.

PMID- 4356774
TI  - Rapid method for the concentration and partial purification of herpes simplex
      viruses types 1 and 2. Brief report.

PMID- 4356776
TI  - Preliminary report of results of Harris total hip replacement.

PMID- 4356777
TI  - Interim results of Charnley-Muller total hip arthroplasty.

PMID- 4356775
TI  - Spin label motion in fatty acids.
AB  - Spin labels dissolved in highly purified fatty acid systems exhibit nearly
      identical tumbling rates in liquid and solid phases. Even though the spin labels
      do not have the same molecular geometry as the lipid matrix the melting point of
      the matrix can be inferred by measurements of the temperature dependency of
      molecular motion.

PMID- 4356778
TI  - Total hip replacement using the "Brunswik-system".

PMID- 4356779
TI  - Evaluation of total hip replacement arthroplasties.

PMID- 4356780
TI  - The Stanmore metal on metal total hip prosthesis using a three pin type cup. A
      follow-up of 100 arthroplasties over nine years.

PMID- 4356781
TI  - Results in patients with total hip replacement arthroplasty.

PMID- 4356782
TI  - Complications revisited. The debit side of total hip replacement.

PMID- 4356783
TI  - [Role of phospholipids in activation and inhibition of thromboplastins].

PMID- 4356784
TI  - Structural studies by proton NMR of cytochrome C-557 from Crithidia oncopelti.

PMID- 4356785
TI  - Alteration of subcellular organelles induced by compression.

PMID- 4356786
TI  - Direct measurement of the midpoint potential of the primary electron acceptor in
      Rhodopseudomonas spheroides in situ and in the isolated state: some relationships
      with pH and o-phenanthroline.

PMID- 4356788
TI  - Prostaglandin production by neuroblastoma, glioma and fibroblast cell lines;
      stimulation by N6,02'-dibutyryl adenosine 3':5'-cyclic monophosphate.

PMID- 4356790
TI  - [Herpes simplex virus and cervix cancer].

PMID- 4356787
TI  - Distinction between oxidizing and reducing sites of cytochrome c by chemical
      modification with pyridoxal phosphate.

PMID- 4356789
TI  - Electron spin resonance spectra of feline NO-hemoglobins.

PMID- 4356791
TI  - Unifying concepts in the response of mammalian cells to stimuli.

PMID- 4356792
TI  - Primary pulmonary scar carcinomas.

PMID- 4356793
TI  - [Catalytically active nitrogenase centers].

PMID- 4356795
TI  - [Effect of hormones on water-electrolyte metabolism].

PMID- 4356794
TI  - [Comparative cytological study of 2 strains of Xanthomonas malvacearum with
      different degress of virulence].

PMID- 4356796
TI  - The bone scintiphotographic examination with 99Tc-tin-pyrophosphate.

PMID- 4356797
TI  - Cation-exchange properties of dry silicate membranes.

PMID- 4356798
TI  - Role of cyclic AMP in the control of epidermal cell growth and differentiation.

PMID- 4356799
TI  - [A recent case of accelerated bone development and somato-mental retardation].

PMID- 4356800
TI  - Suppression by vitamins D2 and D3 of hamster cheek pouch carcinoma induced with
      9,10-dimethyl-1,2-benzanthracene with a discussion of the role of intracellular
      calcium in the development of tumors.

PMID- 4356801
TI  - Effect of phenobarbital on MHV-3 viral hepatitis of the mouse.

PMID- 4356803
TI  - [The glomus jugulare and its tumors].

PMID- 4356802
TI  - [Liver changes under the effect of chronic experimental intoxication with
      nitrogen oxides].

PMID- 4356804
TI  - [Tumors of the petrous pyramid].

PMID- 4356805
TI  - [Ultraweak luminescence and free-radical oxidation in animal tissue metabolism].

PMID- 4356806
TI  - The suprasellar meningioma. A review of the literature and presentation of a
      series of 31 cases.

PMID- 4356807
TI  - Genetics and physiology of colour vision ("my story on colour vision genetics and
      physiology").

PMID- 4356809
TI  - [Recent data concerning nociceptive integration: importance of the spinal
      mechanisms].

PMID- 4356808
TI  - Growth hormone and prolactin in unipolar and bipolar depressed patients:
      responses to hypoglycemia and L-dopa.

PMID- 4356810
TI  - Pseudomonas corneal ulceration: an electron microscopic study.

PMID- 4356811
TI  - Corneal collagenases: evidence for zinc metalloenzymes.

PMID- 4356812
TI  - Palpebral metastasis of mammary carcinoma: an electron microscopic study.

PMID- 4356813
TI  - The effect of neuraminidase treatment of ribosome-free membranes on their
      ribosomal reattachment ability.

PMID- 4356814
TI  - Similarity of the 0.35 M NaCl soluble nuclear proteins and the nonhistone
      chromosomal proteins.

PMID- 4356815
TI  - Action of the S1 endonuclease from Aspergillus oryzae on simian virus 40
      supercoiled component I DNA.

PMID- 4356816
TI  - Active subunits of rabbit liver fructose diphosphatase.

PMID- 4356817
TI  - Subunits of oncornavirus high-molecular-weight RNA. II. Detection of double
      stranded-regions in 60S AMV (avian myeloblastosis virus) RNA.

PMID- 4356818
TI  - Modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with cAMP
      and wth protein fractions of rat liver cytosol.

PMID- 4356819
TI  - Calorimetric investigation of binding of NADH to pig muscle lactate
      dehydrogenase.

PMID- 4356820
TI  - pH induced increase in cyclic GMP reactivity with cyclic AMP-dependent protein
      kinases.

PMID- 4356821
TI  - Specificity of reticulocyte initiation factors for the translation of globin
      messenger RNA.

PMID- 4356822
TI  - Increased capacity for RNA synthesis in Dictyostelium discoideum nuclei induced
      by exposure to cyclic AMP or 5'-AMP.

PMID- 4356823
TI  - Angiotensin binding to rat adrenal capsular cell suspensions.

PMID- 4356824
TI  - Influence of protease inhibitors and energy metabolism on intracellular protein
      breakdown in starving Escherichia coli.

PMID- 4356825
TI  - Effect of ACTH on biosynthesis of aldosterone and corticosterone by monolayer
      cultures of rat adrenal zona glomerulosa cells.

PMID- 4356826
TI  - Utilization of C20-polyunsaturated fatty acids by a yeast fatty acid desaturase
      mutant.

PMID- 4356829
TI  - A qualitative haemoglobin assessment method.

PMID- 4356827
TI  - Effect of poly(ADP-ribose) formation on DNA synthesis and DNA fragmentation in
      nuclei of rat liver and rat ascites hepatoma AH-130 cells.

PMID- 4356828
TI  - Unique nucleotide sequence adjacent to the poly (A) region in yeast RNA.

PMID- 4356830
TI  - [Incidence of nephroblastomas in immunosuppressed Sprague-Dawley rats treated
      with DMBA].

PMID- 4356832
TI  - DNA-dependent RNA polymerase in germinating bean rust uredospores.

PMID- 4356831
TI  - Effect of aldehyde fixatives on the adenosine phosphatases and ultrastructure of
      Vitreoscilla.

PMID- 4356833
TI  - Tyrosinase from embryonic chick retinal pigment epithelium.

PMID- 4356834
TI  - D-galactosamine hepatotoxicity. 3. Normoactive smooth endoplasmic reticulum and
      modification by phenobarbital.

PMID- 4356836
TI  - Differential distribution of angiotensin converting enzyme in the anterior and
      posterior lobe of the rat pituitary.

PMID- 4356835
TI  - Phosphorylation and redox states in ischemic liver.

PMID- 4356837
TI  - Proteins in the degenerative retina of C3H mice: deficiency of a cyclic
      nucleotide phosphodiesterase and opsin.

PMID- 4356839
TI  - Subcellular localization of (14C)adenine derivatives newly-formed in cerebral
      tissues and the effects of electrical excitation.

PMID- 4356838
TI  - Histamine-dependent formation of N-acetyl-aspartyl peptides in mouse brain.

PMID- 4356840
TI  - Glyceride metabolism in cultured cells dissociated from rat cerebral cortex.

PMID- 4356841
TI  - A rapid fluorometric assay for 2',3'-cyclic adenosine monophosphate 3'
      phosphoesterhydrolase.

PMID- 4356842
TI  - Letters: A simple sphingomyelinase determination for Niemann-Pick disease:
      differential diagnosis of types A, B and C.

PMID- 4356843
TI  - Matching of facilitation at the neuromuscular junction of the lobster: a possible
      case for influence of muscle on nerve.
AB  - 1. The facilitation of neuromuscular transmission, which occurs during repetitive
      activation, was examined in the proximal accessory flexor muscle in walking legs
      of the lobster using electrophysiological techniques.2. Post-synaptic potentials
      (p.s.p.s) in different muscle fibres facilitated to markedly different degrees.
      P.s.p.s in some fibres did not facilitate at all, while in others they increased
      in size by 20-30 times during stimulation at 20 Hz even though all the excitatory
      neuromuscular synapses are made by a single axon.3. Stimulation of widely
      separated groups of synapses on any single muscle fibre evoked p.s.p.s with
      closely matched facilitation properties. Extracellular p.s.p.s recorded from
      single synaptic spots showed the same characteristics of facilitation as those of
      intracellular p.s.p.s in the same muscle fibre, suggesting that individual
      synaptic contacts on any single fibre are similar to each other.4. Facilitation
      can be accounted for by an increase in the number of quanta released from the
      nerve terminals. There is no evidence for an increase in post-synaptic membrane
      sensitivity.5. Low Ca solutions reduce transmitter release with comparatively
      little change in facilitation, while Cs solutions increase the size of p.s.p.s
      without increasing the amplitude of spontaneous miniature potentials. Thus, at
      poorly facilitating synapses it is unlikely that the absence of facilitation is
      caused by the saturation of some post-synaptic process.6. It is concluded that
      the excitatory presynaptic nerve terminals on a single muscle fibre have matching
      facilitation characteristics. Some interaction between individual muscle fibres
      and their associated nerve endings may be required to establish or maintain this
      matching.

PMID- 4356844
TI  - The electronic structure of and conformational energy barrier to rotation a round
      the C-N glycosidic linkage in adenosine-3',5'-cyclicmonophosphate (cyclic AMP)
      and its phosphonate analog.

PMID- 4356845
TI  - A comparative study of electronic and neural networks involved in pattern
      recognition.

PMID- 4356846
TI  - Hyperlipoproteinemia. Some basic concepts on diagnosis and management.

PMID- 4356847
TI  - The Coronary Drug Project. Findings leading to discontinuation of the 2.5-mg day
      estrogen group. The coronary Drug Project Research Group.

PMID- 4356848
TI  - Shock during oral glucose tolerance testing.

PMID- 4356849
TI  - Expression of human red cell acid phosphatase activity in placenta and other
      tissues.

PMID- 4356851
TI  - [Mixed tumor of the cortical layer of the adrenals].

PMID- 4356850
TI  - Properties of human serum factors precipitating bovine enterovirus.

PMID- 4356852
TI  - [Late results of the operative treatment of stomach cancer].

PMID- 4356853
TI  - Immunoglobulins and measles antibodies in optic neuritis.

PMID- 4356855
TI  - Letter: Viral hemorrhagic cystitis.

PMID- 4356856
TI  - Tumour specific cell surface antigen and Forssman antigen associated with rat and
      hamster cells transformed with different strains of avian sarcoma virus.

PMID- 4356854
TI  - Letter: Intranuclear virus-like particles and cytoplasmic HbAg in chronic
      hepatitis.

PMID- 4356857
TI  - Isolation of C-type RNA-viruses from stable cell cultures of human tumours.

PMID- 4356858
TI  - Early production of Rous sarcoma virus in cocultivated virogenic mammalian and
      chick embryo cells.

PMID- 4356859
TI  - Isozyme patterns of hepatomas and tumour progression.

PMID- 4356860
TI  - Ultrastructural organ-specificity and polymorphism of the cancer cells.

PMID- 4356861
TI  - Cell surface alterations in transformed and mitotic normal cells monitored with
      plant agglutinins.

PMID- 4356862
TI  - Interactions of normal and neoplastic cells with various surfaces.

PMID- 4356863
TI  - [Scintiphotography of primary hepatocellular carcinoma with 75Se-selenomethionine
      (author's transl)].

PMID- 4356864
TI  - [May-Hegglin anomaly].

PMID- 4356865
TI  - [Dyscalculia with brain tumors].

PMID- 4356866
TI  - Hematopoietic colony formation in a macrophage layer provided by intraperitoneal
      insertion of cellulose acetate membrane.

PMID- 4356868
TI  - Liaison nurse: ombudsman for the chronically ill.

PMID- 4356867
TI  - Studies of immunological reactivity following syngeneic or allogeneic marrow
      grafts in man.

PMID- 4356869
TI  - Extrachromosomal DNA in bacteria.

PMID- 4356871
TI  - Letter: Female sterility produced by investigation.

PMID- 4356870
TI  - Measles and other virus-specific immunoglobulins in multiple sclerosis.
AB  - Immunoglobulins M and G specific for meales, herpes simplex, and rubella viruses
      were assayed by the fluorescent antibody method in sera and cerebrospinal fluids
      (C.S.F.) obtained simultaneously from 30 patients with multiple sclerosis, 30
      patients with other neurological diseases, and 30 "normal" control subjects. Sera
      of 11 out of 30 patients with multiple sclerosis had IgM which reacted
      specifically with measles virus-infected cells, compared with 2 out of 30 of the
      patients with other neurological diseases and none of the 30 normal controls.
      Virus-specific IgM was not found in C.S.F. by this method.The geometric mean
      titre of measles virus-specific IgG in serum was significantly higher in the
      multiple sclerosis group than in either control group, and while IgG specific for
      all three viruses was found in C.S.F., suggesting transfer across the blood-brain
      barrier, measles IgG predominated.

PMID- 4356872
TI  - Letter: Protection of cytomegalovirus-infected cells by IgG antibody.

PMID- 4356874
TI  - Synovioma in a dog.

PMID- 4356873
TI  - Distribution of a polychlorinated terphenyl (PCT) (Aroclor 5460) in rat tissues
      and effect on hepatic microsomal mixed function oxidases.

PMID- 4356875
TI  - Studies on nucleotide analogs. I. Synthesis of two 9-alpha-D
      mannofuranosyladenine phosphates, and their inhibition of adenylate kinase.

PMID- 4356876
TI  - [Effect of the silane treatment of mineral surface of the metal, porcelain and
      hard dental tissues on the properties and adhesion of a new acrylic filling
      materials].

PMID- 4356877
TI  - [Syndactylia with hypoplasia of the fingers].

PMID- 4356878
TI  - The chemical composition of algal cell walls.

PMID- 4356880
TI  - [Substitution therapy with equiline sulfate in menopausal women].

PMID- 4356881
TI  - Cyclic AMP and thyroid hormone synthesis. I. Stimulation of the biosynthesis of
      thyroglobulin-related polypeptides and proteins in bovine thyroid slices.

PMID- 4356882
TI  - Editorial: A progress report on lipoprotein phenotyping.

PMID- 4356879
TI  - [ACTH and summary 11-hydroxycorticosteroids of the blood in endovesical
      therapeutic and diagnostic interventions under sombrevin anesthesia in urology].

PMID- 4356883
TI  - Effect of epinephrine on platelet lipid metabolism.

PMID- 4356884
TI  - Glycerol-induced acute renal failure after acute plasma renin activity
      suppression.

PMID- 4356885
TI  - Interaction of cultured human fibroblasts with fibrin: modification by drugs and
      aging in vitro.

PMID- 4356886
TI  - Phosphatidate phosphatase in human platelets.

PMID- 4356887
TI  - Recent advances in canine virus research.

PMID- 4356888
TI  - Protection of dogs against canine hepatitis with Toronto A26-61 virus (kennel
      cough isolate) hexon antigen.

PMID- 4356889
TI  - Segmental resection for lung cancer. A fifteen-year experience.

PMID- 4356891
TI  - [Errors in the diagnosis of bronchiolo-alveolar carcinoma].

PMID- 4356890
TI  - Acute obstruction of tricuspid valve by Wilms' tumor.

PMID- 4356892
TI  - Case for diagnosis. Wilm's tumor.

PMID- 4356893
TI  - Mutagenicity of dichlorvos and methyl methanesulphonate for Escherichia coli WP2
      and some derivatives deficient in DNA repair.

PMID- 4356894
TI  - The nature of single-strand breaks in DNA following treatment of L-cells with
      methylating agents.

PMID- 4356895
TI  - Letter to the editor: Dosimetry of the chemical mutagen Ethylmethanesulfonate.

PMID- 4356896
TI  - Effects of irradiation on the responses of animal cells to virus.

PMID- 4356897
TI  - Virus diseases associated with cutaneous eruptions.

PMID- 4356898
TI  - Viruses in human carcinogenesis.

PMID- 4356899
TI  - Differences between extracellular and intracellular forms of poxvirus and their
      implications.

PMID- 4356900
TI  - [Occurrence of fungi imperfecti and chemical composition of water and soil in the
      environment of patients with tumors at the village of Liszki (Cracow County)].

PMID- 4356901
TI  - [Viral pathology: concepts of yesterday and today].

PMID- 4356903
TI  - [Toxin formation by Cl. perfringens on a casein-pancreatic medium].

PMID- 4356902
TI  - Letter: Insulin activity: the solid matrix.

PMID- 4356905
TI  - The formation and degradation of granules in eosinophil cells.

PMID- 4356904
TI  - An electron microscopic study of the neuroglial reaction in the hypoglossal
      nucleus after transection of the hypoglossal nerve.

PMID- 4356906
TI  - Studies on the urophysis and the caudal neurosecretory system in a teleost, Ompok
      bimaculatus (Bloch).

PMID- 4356907
TI  - Studies on boar semen. I. A new major defect in the sperm head, the "SME"-defect.

PMID- 4356908
TI  - Studies on boar semen. II. Abnormal mitochondrial helix "pseudo-corkscrew sperm"
      due to ejaculation in the preputial cavity.

PMID- 4356909
TI  - Pediatric oncology.

PMID- 4356910
TI  - Derivatives of aziridine as inactivants for foot-and-mouth disease virus
      vaccines.

PMID- 4356911
TI  - The influence of short ether anesthesia on some liver enzyme activities in the
      rat.

PMID- 4356912
TI  - Collagenolytic activity in rheumatoid synovial tissue.

PMID- 4356913
TI  - A stable uterine binding protein preparation for the assay of plasma oestriol in
      pregnancy.

PMID- 4356915
TI  - The effects of adrenalin, glucagon, insulin and dibutyryl cyclic AMP on liver and
      serum alpha-amylase activities in the rat.

PMID- 4356914
TI  - Physical and chemical factors influencing the reliability of the assay of
      androgens by competitive protein binding.

PMID- 4356916
TI  - Alcohol dehydrogenase in Mucorales. II.

PMID- 4356917
TI  - [Zollinger-Ellison syndrome associated with diabetes mellitus].

PMID- 4356918
TI  - [Cytochemical characteristics of leukemic cells in CC57BR line of mice with acute
      leukemia induced by Mazurenko's virus].

PMID- 4356919
TI  - [Comparative study of an inhibitor of liver catalase isolated from various
      tissues of the CC57BR mice strain with Mazurenko's viral leukemia].

PMID- 4356920
TI  - [Clinical study of sensitivity. Anatomo-physiological bases, methods of
      examination, international evaluation standard, and recovery of sensation
      following lesions of the peripheral nerves].

PMID- 4356921
TI  - [Differential diagnosis of nerve diseases and surgical lesions of the peripheral
      nerves (upper and lower limbs)].

PMID- 4356922
TI  - [Somatic development during puberty].

PMID- 4356924
TI  - [Effect of certain drug substances in late pregnancy toxicosis on the fetal
      cardiac activity].

PMID- 4356923
TI  - [Free skin radicals in psoriasis and their relationship to oxidation-reduction
      processes].

PMID- 4356925
TI  - [Changes in the monocytogram in adenovirus pneumonia in children].

PMID- 4356926
TI  - [Age-related histopathology of the peripheral neuron].

PMID- 4356927
TI  - [Study of the kinin system enzymes and a justification for the use of proteolysis
      inhibitors in rheumatoid polyarthritis].

PMID- 4356929
TI  - In vitro and in vivo studies with Epstein-Barr virus (EBV). A review.

PMID- 4356930
TI  - Epstein-Barr virus: stimulation by 5'-iododeoxyuridine or 5'-bromodeoxyuridine in
      human lymphoblastoid cells from a rhabdomyosarcoma.

PMID- 4356931
TI  - [Loganiaceae of the Ivory Coast. XI. Strychnos usambarensis Gilg alkaloids].

PMID- 4356932
TI  - [Value of the abrodil myelography in preoperative segmental diagnosis of
      intervertebral disk prolapse].

PMID- 4356933
TI  - Activity and some properties of choline kinase, cholinephosphate
      cytidyltransferase and choline phosphotransferase during liver development in the
      rat.

PMID- 4356935
TI  - [Melanin pigments in thermophilic actinomycetes].

PMID- 4356934
TI  - Isolation and characterization of a sialoglycolipid from the sea urchin
      Strongylocentrotus intermedius.

PMID- 4356936
TI  - The role of the raphe nuclei in the regulation of ponto-geniculo-occipital wave
      activity.

PMID- 4356937
TI  - Electrophysiology of the frontal granular cortex. I. Patterns of focal field
      potentials evoked by stimulations of dorsomedial thalamus in conscious monkey.

PMID- 4356938
TI  - Transmitter role of serotonin in identified synapses in Aplysia nervous system.

PMID- 4356939
TI  - Effect of dibutyryl cyclic AMP on cell proliferation of adenohypophysis in organ
      culture. Preliminary report.

PMID- 4356940
TI  - [Clinical evaluation of trimcinolone effect on inhibiting the corticotropic
      activity of the hypophysis].

PMID- 4356941
TI  - The effect of number of stimuli and rate of stimulation on the inhibition by PGE1
      of adrenergic transmission.

PMID- 4356942
TI  - Selective microvascular constrictor actions of some neurohypophyseal peptides.

PMID- 4356943
TI  - A controlled trial of a new combined preparation for the treatment of
      constipation in geriatric patients.

PMID- 4356944
TI  - [Alpha fetoprotein in hemorrhagic ascitic fluid in a case of hepatocellular
      carcinoma].

PMID- 4356945
TI  - The frequency of excretion of cysts of Entamoeba histolytica in known cases of
      non-dysenteric amoebic colitis based on 21 stool examinations.

PMID- 4356946
TI  - Studies on proteolytic activity of mycoplasmas: the preparation and properties of
      gelatinolytic enzymes from strains of Mycoplasma arthritidis.

PMID- 4356948
TI  - Hospital discharge planning: a hospital's responsibility to the patient and the
      community.

PMID- 4356949
TI  - [The ancient chinese science of the pulse].

PMID- 4356947
TI  - Formation of extracellular haemolysin by Aeromonas hydrophila in relation to
      protease and staphylolytic enzyme.

PMID- 4356950
TI  - Diagnosis, prognosis and treatment of peripheral neuropathies.

PMID- 4356951
TI  - Polishing dental enamel.

PMID- 4356952
TI  - [Pathogenesis of severe forms of alopecia areata].

PMID- 4356953
TI  - [Plasma kinins and their significance in pathology of the respiratory organs].

PMID- 4356954
TI  - [Impulse current treatment of patients with diseases of the peripheral nervous
      system].

PMID- 4356955
TI  - [Lactotherapy for pox in camels].

PMID- 4356956
TI  - [Clostridium perfringens contamination of beef].

PMID- 4356957
TI  - [Interaction of the virus of hoof-and-mouth disease with tissue culture cells (a
      survey of the literature)].

PMID- 4356958
TI  - [Determination of the correspondence of epizootic strains of the foot-and-mouth
      disease virus to the cultured ones].

PMID- 4356959
TI  - [Management of climacteric disorders in clinical practice].

PMID- 4356960
TI  - [Quantitative and simultaneous determination of quartz, tridymit and cristobalit
      in dusts using infrared spectroscopy].

PMID- 4356961
TI  - [Polyvinylpyrididine-N-oxide and pulmonary changes in rats powdered with carbon
      dust].

PMID- 4356964
TI  - The problem of pathogenicity in parasitic entamoeba.

PMID- 4356962
TI  - [Phospholipids and their fatty acids in the brain and electric organ of Torpedo
      marmorata].

PMID- 4356963
TI  - Hemoglobin H-beta-thalassemia.

PMID- 4356965
TI  - [A case of diffuse reticulosis of the nervous system].

PMID- 4356966
TI  - [Neuromuscular complications in the course of panhypopituitarism. (Description of
      a case)].

PMID- 4356967
TI  - Gas-phase electron paramagnetic resonance detection of nitric oxide and nitrogen
      dioxide in polluted air.

PMID- 4356968
TI  - Localization and correltion of catecholamine-containing cells with adenyl cyclase
      nd phosphodiesterase activities in the human fetal heart.

PMID- 4356969
TI  - The degeneration and disappearance of the centrioles during the development of
      the rat spermatozoon.

PMID- 4356970
TI  - X-ray abnormalities in tetra X females. (Report on two cases).

PMID- 4356972
TI  - "Super-reduction" of chromatium high-potential iron-sulphur protein in the
      presence of dimethyl sulphoxide.

PMID- 4356971
TI  - Artificial proteolipids: cytochrome c-detergent complexes soluble in isooctane.

PMID- 4356973
TI  - The effect of cyclic AMP on anaerobic growth of Escherichia coli.

PMID- 4356974
TI  - A synthetic tripeptide which increases survival of normal liver cells, and
      stimulates growth in hepatoma cells.

PMID- 4356975
TI  - A specific glucocorticoid binding macromolecule of rabbit uterine cytosol.

PMID- 4356976
TI  - Periodic change in the content of adenosine 3'5'-cyclic monophosphate with close
      relation to the cycle of cleavage in the sea urchin egg.

PMID- 4356977
TI  - A cytoplasmic membrane-associated DNA from rapidly proliferating tissue.

PMID- 4356978
TI  - Resolutions and identification of the core deoxynucleoproteins of the simian
      virus 40.

PMID- 4356979
TI  - Cyclic nucleotide-independent protein kinase from pea shoots.

PMID- 4356980
TI  - Stimulation of ovarian cyclic guanosine 3',5'-monophosphate levels by the
      subunits of human chorionic gonadotropin.

PMID- 4356981
TI  - Studies on the immunochemical and functional similarities among iron-sulfur
      proteins involved in mitochondrial steroid hydroxylations.

PMID- 4356982
TI  - Carbohydrate composition of lipoprotein apoproteins isolated from rat plasma and
      from the livers of rats fed orotic acid.

PMID- 4356983
TI  - Inhibition of protein synthesis directed by added viral and cellular messenger
      RNAs in extracts of interferon-treated Ehrlich ascites tumor cells. Location and
      dominance of the inhibitor(s).

PMID- 4356984
TI  - The stimulation of dopa decarboxylase activity by ecdysone and its enhancement by
      cyclic AMP in adult mosquitoes.

PMID- 4356985
TI  - Multiple cytochromes b in Mycobacterium phlei.

PMID- 4356986
TI  - The phosphorylation of troponin B by phosphorylase b kinase in skeletal muscle of
      mice carrying the phosphorylase b kinase deficiency gene.

PMID- 4356988
TI  - Hypothalamo-hypophysial neurosecretion. II. Hypophysectomy, ACTH and metopiron
      treatment in Bufo andersonii.

PMID- 4356987
TI  - A follow-up study of 211 treated male alcoholic addicts.

PMID- 4356989
TI  - The Poland syndrome-clinical and genealogical data, dermatoglyphic analysis, and
      incidence.

PMID- 4356990
TI  - Morphogenesis of calcium laden cytoplasmic bodies in malakoplakia of the skin. An
      electron microscopic study.

PMID- 4356991
TI  - Virulence of E. histolytica strains isolated from cases of amoebiasis in New
      Delhi, India.

PMID- 4356992
TI  - Location of heme a in cytochrome a. II. Solvent perturbation spectroscopy of
      ferricytochrome a.

PMID- 4356993
TI  - Some characteristics of phosphorylation reactions in rat-liver mitochondria
      incubated without the addition of adenine nucleotides and their relation to
      substrate-level phosphorylation.

PMID- 4356994
TI  - Regulation of rabbit liver fructose diphosphatase. I. Reversible inactivation by
      oxidized glutathione.

PMID- 4356995
TI  - Juvenile angiofibroma. Report of a case occurring within the mouth.

PMID- 4356996
TI  - A hand sign.

PMID- 4356997
TI  - Studies on cyclic nucleotides in the adrenal gland. II. Properties of cyclic AMP
      dependent protein kinases in the adrenal gland.

PMID- 4356998
TI  - Antitumor activity of DL-1-beta-chloroethyl-2-chloromethylpiperidine hydrobromide
      (CAP-1) on some rodent tumors.

PMID- 4356999
TI  - The action of dibutyryl cyclic GMP (N2-2'-O-dibutyryl cyclic guanosine-3',5'-mono
      phosphate) on the ileum of guinea pig.

PMID- 4357001
TI  - Specific pressor activity of angiotensins I and II.

PMID- 4357000
TI  - Effect of serotonin, glucagon and other hormones on amylase secretion from rabbit
      parotid gland.

PMID- 4357003
TI  - [Juvenile angiofibroma of maxillary sinus].

PMID- 4357002
TI  - The effect of oxytocin on renal blood flow and its distribution in the dog.

PMID- 4357005
TI  - [Current aspects of human herpes virus infections].

PMID- 4357004
TI  - [Effect of Thio-TEPA on advanced ovarian cancer (author's transl)].

PMID- 4357007
TI  - [Herpesvirus hominis type 2 and Epstein-Barr virus antibodies in patients with
      cancer of the uterine cervix].

PMID- 4357006
TI  - [Postoperative cytomegalovirus and Epstein-Barr virus infections. The value of
      exended serologic diagnosis in patients submitted to heart operations].

PMID- 4357008
TI  - [Use of the fluorescent antibody method in rapid diagnosis of Herpesvirus hominis
      (herpes simplex virus)].

PMID- 4357009
TI  - [Should we contnue to use disulfiram (Antabus)].

PMID- 4357010
TI  - [Histomorphological changes in the skin in Duhring's herpetiform dermatitis].

PMID- 4357011
TI  - [The significance of sebaceous cells and sebaceous glands in parotid tumors
      (author's transl)].

PMID- 4357013
TI  - Ultrastructure of the abnormal human trophoblast.

PMID- 4357012
TI  - [Effect of protein malnutrition and of kennel-keeping conditions on the function
      of the adrenal cortex in broilers].

PMID- 4357014
TI  - A contribution to the knowledge of the hypo-beta-lipoproteinemia.

PMID- 4357015
TI  - Paediatric pharmacology.

PMID- 4357016
TI  - [Ultrastructure of human skeletal muscles].

PMID- 4357019
TI  - Lipid- and temperature-dependent structural changes in Acholeplasma laidlawii
      cell membranes.

PMID- 4357020
TI  - Calcium binding by a plasma membrane fraction isolated from rat submandibular
      glands.

PMID- 4357022
TI  - Behcet's disease with recurrent facial paralysis.

PMID- 4357021
TI  - Action of snake venom hemorrhagic principles on isolated glomerular basement
      membrane.

PMID- 4357023
TI  - A test for space clustering and its application to congenital limb defects in
      Cardiff.

PMID- 4357017
TI  - Autotrophic CO2 assimilation and the evolution of ribulose diphosphate
      carboxylase.

PMID- 4357018
TI  - Proteins from thermophilic microorganisms.

PMID- 4357024
TI  - Gel entrapment of antibody: a new strategy for facilitating both manual and
      automated radioimmunoassay.

PMID- 4357025
TI  - Letter: Lipoprotein electrophoresis.

PMID- 4357026
TI  - [Clinical features of herpes simplex encephalitis].

PMID- 4357027
TI  - [ACTH treatment in Guillain-Barre syndrome].

PMID- 4357028
TI  - [Skin signs of internal cancer].

PMID- 4357029
TI  - Effect of cell chromosome number on simian virus 40 replication.

PMID- 4357030
TI  - Nuclear membranes from mammalian liver. VI. Glucose-6-phosphatase in rat liver, a
      cytochemical and biochemical study.

PMID- 4357031
TI  - Growth induction by serum or polyoma virus inhibits the aggregation of
      trypsinised suspensions of BHK21 tissue culture fibroblasts.

PMID- 4357032
TI  - Studies on cellular adhesion in tissue culture. XIIA. Some effects of
      prostaglandins and cyclic nucleotides.

PMID- 4357033
TI  - Contact-inhibited revertant cell lines isolated from SV40-transformed cells. V.
      Contact inhibition of sugar transport.

PMID- 4357034
TI  - A permanent line of macrophages with normal activity in a primary antibody
      response in vitro.

PMID- 4357035
TI  - A Merkel cell nuclear inclusion.

PMID- 4357036
TI  - [Various clinical pictures of trophoblastic neoplasia (author's transl)].

PMID- 4357038
TI  - Editorial: Leukocyte movement--in vitro and in vivo correlates.

PMID- 4357037
TI  - Scalp vesicles within the first week of life: a clue to early diagnosis of herpes
      neonatorum.

PMID- 4357039
TI  - Defect of neutrophil motility in a child with recurrent bacterial infections and
      disseminated cytomegalovirus infection.

PMID- 4357040
TI  - Renovascular hypertension secondary to hydronephrosis in a solitary kidney.

PMID- 4357041
TI  - International certificates of vaccination.

PMID- 4357042
TI  - Long-term evaluation of single versus multiple courses of actinomycin D therapy
      of Wilms's tumor.

PMID- 4357043
TI  - Lymphocyte inclusions in newborns of mothers with systemic lupus erythematosus.

PMID- 4357044
TI  - Vitamin D-induced synthesis of mRNA for calcium-binding protein.

PMID- 4357045
TI  - Antibodies to simian C-type virus antigen in sera of gibbons (Hylobates sp.).

PMID- 4357046
TI  - Leakage of cyclic AMP from human diploid fibroblasts in tissue culture.

PMID- 4357047
TI  - Postpartum bilateral femoral neuropathy.

PMID- 4357048
TI  - [Various rare benign tumors in the oral cavity and jaw region].

PMID- 4357049
TI  - Choline phosphokinase, phosphorylcholine cytidyltransferase and CDP-choline: 1,2
      diglyceride cholinephosphotransferase activity in developing rat lung.

PMID- 4357051
TI  - A comparison of the virus-specific polypeptides of encephalomyocarditis virus,
      human rhinovirus-1A, and poliovirus.

PMID- 4357050
TI  - Enhancement of viral infectivity by cytochalasin.

PMID- 4357052
TI  - Avian oncornavirus-induced tumor antigens of embryonic and unknown origin.

PMID- 4357053
TI  - Rescue of vesicular stomatitis virus from interferon-induced resistance by
      superinfection with vaccinia virus. I. Rescue in cell cultures from different
      species.

PMID- 4357054
TI  - Rescue of vesicular stomatitis virus from interferon-induced resistance by
      superinfection with vaccinia virus. II. Effect of UV-inactivated vaccinia and
      metabolic inhibitors.

PMID- 4357055
TI  - Early synthesis of virus-specific RNA and DNA in cells rapidly transformed with
      Rous sarcoma virus.

PMID- 4357056
TI  - DNA replication in SV40-infected cells. IX. The inhibition of a gap-filling step
      during discontinuous synthesis of SV40 DNA.

PMID- 4357057
TI  - [Pulmonary adenomatosis].

PMID- 4357058
TI  - [Biochemical and histomorphological changes in experimental hexachlorbenzol
      porphyria (author's transl)].

PMID- 4357059
TI  - Cytotoxic action of spleen lymphocytes to simian virus 40-induced tumor cells.

PMID- 4357060
TI  - Tumorigenesis of adenovirus-SV 40 hybrids in hamsters.

PMID- 4357061
TI  - Mixed mesodermal tumor of the ovary.

PMID- 4357062
TI  - Fine structure of the differentiating acini in submandibular glands of
      isoproterenol-treated rats.

PMID- 4357063
TI  - Large inclusions in receptor cells of the amphibian lateral line.

PMID- 4357064
TI  - The corticotroph of the rat adenohypophysis: a comparative study.

PMID- 4357065
TI  - Cortisol and growth hormone response to surgical stress during morphine
      anesthesia.

PMID- 4357066
TI  - [Mononucleosic post-transfusion syndromes and cytomegalic viruses. Prospective
      study of 13 cases].

PMID- 4357067
TI  - Tracheal obstruction.

PMID- 4357068
TI  - Cholinergic responses and adrenergic-cholinergic interactions in the mesenteric
      vascular bed.

PMID- 4357069
TI  - Effect of disulfiram on the urinary D-glucaric acid excretion and activity of
      some enzymes involved in drug metabolism in guinea-pig.

PMID- 4357072
TI  - Proceedings: The surgical treatment of nephroblastoma (Wilms' tumor).

PMID- 4357071
TI  - [Morphogenesis of the fetal adrenal cortex in pig's fetuses in relation to the
      development of adenohypophysis].

PMID- 4357070
TI  - The action of polypeptides, amines and prostaglandins on isolated smooth muscle
      preparations of seminal vesicles and deferent ducts.

PMID- 4357074
TI  - Proceedings: Tumors of the adrenal cortex.

PMID- 4357073
TI  - Proceedings: Chemotherapy in Wilms' tumor. An appraisal.

PMID- 4357075
TI  - Herpesvirus cervicitis and cervical neoplasia. A cytologic review.

PMID- 4357076
TI  - Changing pattern of some pathologic parameters of mammary carcinoma.

PMID- 4357077
TI  - Myoepithelioma of the palate. Report of a case with histochemical and electron
      microscopic observations.

PMID- 4357078
TI  - Light and electron microscopic observations on a congenital insulinoma.

PMID- 4357079
TI  - Hepatocellular carcinoma presenting with pathologic fracture due to bone
      metastases.

PMID- 4357080
TI  - Hypoglycemia associated with lipid accumulation in primary hepatocellular
      carcinoma.

PMID- 4357081
TI  - Distribution of serum lipoproteins of selected vertebrates.

PMID- 4357082
TI  - Heart mitochondria oxidations of an Antarctic fish.

PMID- 4357084
TI  - Suppressive effect of dexamethasone on morphine-induced adrenocorticoidogenesis
      in rat.

PMID- 4357083
TI  - [Immunological diagnosis of amoebiasis in persons returning from the tropics
      (author's transl)].

PMID- 4357085
TI  - Effect of synthetic corticotropins on human growth hormone secretion.

PMID- 4357086
TI  - Effect of ACTH on the phosphorylation of proteins in subcellular fractions of rat
      adrenal glands.

PMID- 4357087
TI  - 5Alpha-dihydrotestosterone "receptor" in the rat hypothalamus.

PMID- 4357088
TI  - Nuclear and extranuclear mutations in yeast induced by ethyl methanesulfonate.

PMID- 4357091
TI  - Quantification of antipoliovirus antibodies in human and simian sera.

PMID- 4357090
TI  - Poliovirus antibody in milk and sera of lactating women.

PMID- 4357089
TI  - The production of migration inhibitory factor (MIF) in rabbit lymphocytes by
      other than immunological mechanism.

PMID- 4357092
TI  - Combined action of antiamoebic drugs and antibiotics on axenically grown
      Entamoeba histolytica.

PMID- 4357093
TI  - Adenovirus infections in West Bengal. I. Persistence of viruses in infants and
      young children.

PMID- 4357094
TI  - Encephalomyocarditis virus activity in Mus booduga (Gray) in Barur Village (1961
      1962), Sagar KFD area, Mysore State, India.

PMID- 4357095
TI  - Pseudomonas cepacia tricuspid endocarditis: treatment with trimethoprim,
      sulfonamide, and polymyxin B.

PMID- 4357096
TI  - Sulfonamide structure-activity relationships in a cell-free system. 2. Proof for
      the formation of a sulfonamide-containing folate analog.

PMID- 4357097
TI  - Transcription of mouse mammary tumor virus genes in tissues from high and low
      tumor incidence mouse strains.

PMID- 4357098
TI  - Letter: On the source of "minor thymine" in DNA from a Novik off rat hepatoma
      cell line.

PMID- 4357099
TI  - Ganglion of the posterior tibial nerve. Case report.

PMID- 4357100
TI  - Identification of urinary metabolites of p-phenoxyphenol methanesulfonate in rat
      and man.

PMID- 4357101
TI  - Colorimetric determination of dipyrone.

PMID- 4357102
TI  - Acetonitrile-diatomaceous earth column for separation of steroids and other
      compounds.

PMID- 4357103
TI  - [On the existence of a fast-acting negative feedback control of ACTH
      corticosterone secretion (author's transl)].

PMID- 4357104
TI  - Far advanced malignant external otitis: report of a survival.

PMID- 4357105
TI  - Differential inhibition of catabolite-sensitive enzyme induction by intercalating
      dyes.

PMID- 4357106
TI  - Infectious herpesvirus DNA.

PMID- 4357107
TI  - Controlled expression of SV40 genome.

PMID- 4357109
TI  - Interaction of cytochrome oxidases aa3 and d with nitrite.

PMID- 4357108
TI  - Adenine nucleotide-mediated subunit exchange between isoenzymes of glyceraldehyde
      3-phosphate dehydrogenase.

PMID- 4357110
TI  - Characterisation of the 3'-terminus of Sindbis virion RNA.

PMID- 4357111
TI  - Activation of phosphofructokinase by stimulants of cell multiplication.

PMID- 4357112
TI  - Activation of methaemoglobin peroxidase by inositol hexaphosphate.

PMID- 4357113
TI  - Myopathy associated with Marfan's syndrome. Fine structural and histochemical
      observations.

PMID- 4357114
TI  - Study of long-term anticholinesterase therapy. Effects on neuromuscular
      transmission and on motor end-plate fine structure.

PMID- 4357115
TI  - The effect of sleep on spike-wave discharges in absence seizures.

PMID- 4357117
TI  - Patterns of faecal porphyrin excretion in the hepatocutaneous porphyrias. Thin
      layer chromatography of their methyl esters.

PMID- 4357116
TI  - [Microsurgery of peripheral nerves--review].

PMID- 4357118
TI  - Extensive resection of primary malignant tumors of the left cerebral hemisphere.

PMID- 4357119
TI  - Endemic goiter in Greece: nutritional status, growth, and skeletal development of
      goitrous and non goitrous populations.

PMID- 4357120
TI  - Standardized management of breast specimens recommended by Pathology Working
      Group, Breast Cancer Task Force.

PMID- 4357121
TI  - Increased detection of occult breast carcinoma after more thorough histologic
      examination of breast biopsies.

PMID- 4357122
TI  - Congenital mesoblastic nephroma of infancy: report of a case with unusual
      clinical behavior.

PMID- 4357123
TI  - Cell-mediated immunity to herpes simplex virus in man.

PMID- 4357124
TI  - Bacteriology and in vitro antimicrobial susceptibility of the Pseudomonas
      fluorescens group isolated from clinical specimens.

PMID- 4357125
TI  - Vasoactive substances in the circulation of the pregnant dog during acute fetal
      ischemia.

PMID- 4357127
TI  - Herpes genitalis treated by photodynamic inactivation of virus.

PMID- 4357129
TI  - Decreased cerebrospinal fluid glucose level in herpes zoster meningitis. Report
      of a case.

PMID- 4357128
TI  - The metabolic effects of halothane on mammalian hepatoma cells in vitro. II.
      Inhibition of DNA synthesis.

PMID- 4357126
TI  - Effect of oxytocin on the perfused human placenta in vitro.

PMID- 4357130
TI  - On the treatment of rapid eye movement narcolepsy.

PMID- 4357131
TI  - Adenyl cyclase in normal and pathologic human muscle.

PMID- 4357132
TI  - Immunogenicity of rat hepatoma membrane fractions.
AB  - The principal expression of immunity elicited in syngeneic rats immunized with
      rat hepatoma membrane fractions was the development of a tumour specific antibody
      response. This antibody was demonstrable by membrane immunofluorescence staining
      of viable hepatoma cells in suspension and the sera exhibited complement
      dependent cytotoxicity for cultured hepatoma cells. In the absence of complement,
      however, membrane immune sera were highly "blocking", protecting plated hepatoma
      cells from attack by sensitized lymph node cells. The cell mediated immune
      response elicited by hepatoma membrane immunization was weak, as evaluated by the
      colony inhibitory activity of lymph node cells for hepatoma cells in vitro or the
      adoptive transfer of immunity with peritoneal exudate cells. Correlated with this
      overall pattern of immune response, membrane immunization did not elicit tumour
      rejection reactions. These findings are relevant to current views that humoral
      factors operate antagonistically to limit cell mediated immunity to tumours. A
      further relevant feature was the observation that membrane immunization,
      eliciting a prominent humoral immune reaction, conditioned the recipients so that
      they subsequently failed to elicit a tumour rejection immunity on treatment with
      irradiated tumour cells.

PMID- 4357133
TI  - The behaviour of carcinoma of the large bowel in man following transplantation
      into immune deprived mice.
AB  - The growth of carcinoma of the human large bowel was studied in the first 2
      passages in immune deprived mice. The tumours were obtained from large bowel
      resections on 3 people. There was a strong histological similarity between the
      patient's tumour and the tumour that grew subcutaneously in the mice 2-8 months
      after implantation. One dissimilarity observed was a higher mitotic index in some
      of the tumours growing in the immune deprived animals. In the second passage of
      the bowel tumours, cells were implanted into groups of 8-10 animals in the
      following sites: subcutaneous, intramuscular, intravenous, intrahepatic,
      intraperitoneal and intrathoracic. Growth of tumour was observed from all 3
      tumours when they were implanted subcutaneously, intramuscularly,
      intraperitoneally and intrathoracically. Infiltration of muscle by tumour was a
      frequent finding. Lung metastases developed after intravenous injection of cells
      in 1 of the 3 tumours. In none of the 3 tumours did growth follow injection of
      cells directly into the substance of the liver. On no occasions were spontaneous
      metastases observed.

PMID- 4357134
TI  - Transplantation of human tumour to immune deprived mice treated with anti
      thymocyte serum.
AB  - Five out of 18 primary explants of human carcinomata obtained at operation have
      been grown progressively for a minimum of one month in thymectomized, x
      irradiated mice reconstituted with syngeneic bone marrow and subsequently treated
      also with anti-thymocyte serum. All the tumours which proliferated were of
      gastrointestinal origin, growing locally but not metastasizing although direct
      invasion of the ribs occurred in one case. No implanted breast carcinomata grew
      in this system.

PMID- 4357135
TI  - Substitution of beclomethasone aerosol for oral prednisolone in the treatment of
      chronic asthma.
AB  - In a double-blind study 10 patients with chronic asthma received beclomethasone
      dipropionate 400 mug daily in a Freon propellant from a pressurized dispenser,
      and 10 patients received the Freon propellant alone. At the start of the trial
      each patient was receiving long-term maintenance treatment with oral prednisolone
      in a dose of 7.5 to 15 mg daily. The daily dose of prednisolone was reduced by 1
      mg every four weeks and the patient's progress followed by regular clinical
      assessment and studies of pituitary-adrenal function. The trial was continued
      until the dose of prednisolone was reduced to zero or until asthmatic symptoms
      increased to an unacceptable level.In the 10 patients who received beclomethasone
      the mean maintenance dose of oral prednisolone was reduced by 5.6 mg/day but in
      only two cases could this drug be withdrawn completely. In the placebo group the
      mean reduction in dose was only 1.3 mg, thus there was a significant difference
      between the two groups (P <0.01). Studies of pituitary-adrenal function showed
      that a normal adrenal response to tetracosactrin stimulation returned only in the
      two patients from whom prednisolone was withdrawn.Hence the addition of
      beclomethasone dipropionate by inhalation to systemic corticosteroid therapy
      allows useful reductions to be made in the oral maintenance doses of
      corticosteroid. Reductions must be made with caution since there is wide
      individual variation in response to beclomethasone and in only a minority of
      patients can oral treatment by completely withdrawn.

PMID- 4357136
TI  - Letter: Type IV hyperlipidaemia in cord blood.

PMID- 4357137
TI  - Problems of interpretation of laboratory findings in the old.

PMID- 4357139
TI  - Editorial: Neonatal kidney tumours.

PMID- 4357138
TI  - Changes in skeletal mineral in patients on prolonged maintenance dialysis.
AB  - The measurement of bone loss in patients undergoing maintenance dialysis over a
      period of two and a half years is reported. The tendency to lose bone is a likely
      event in renal failure, but depends more on the individual patient than on the
      type of dialysis used, provided that steps are taken to prevent avoidable calcium
      loss during dialysis. Vitamin D therapy was an important factor in preventing
      bone loss in some cases. The tendency to lose bone more readily when both kidneys
      were absent may have reflected a deficiency of 1-25 dihydrocholecalciferol. On
      the other hand, bone loss was also observed in transplanted patients. The need to
      measure bone loss at regular intervals once renal failure has been diagnosed is
      stressed.

PMID- 4357140
TI  - Letter: Coma and convulsions associated with vincristine therapy.

PMID- 4357141
TI  - Pediatric infections with respiratory syncytial virus.

PMID- 4357143
TI  - NADH preparations as they affect reliability of serum lactate dehydrogenase
      determinations.

PMID- 4357142
TI  - Respiratory syncytial virus infections in children in Montreal: a retrospective
      study.
AB  - Seventy-seven hospitalized children from whom respiratory syncytial virus was
      subsequently isolated were studied in retrospect. This demonstrated the
      association of host invasion by this agent with an acute respiratory disease
      requiring hospitalization for approximately one week.Boys considerably
      outnumbered girls, the average age was 7.5 months, and in 56% the admission
      diagnosis was "bronchiolitis". Cough and difficulty in breathing were the most
      common presenting complaints and "pneumonia" the most common radiological
      diagnosis. Nearly half the patients also harboured accepted disease-causing
      bacterial pathogens. All the patients recovered and have remained well.The
      appearance of the virus in Montreal was seasonal, beginning in late autumn and
      terminating in early spring.

PMID- 4357144
TI  - Residual fluorescence as an index of purity of reduced nicotinamide adenine
      dinucleotide.

PMID- 4357146
TI  - Preparation of amine salts of thymolphthalein monophosphate and their use for
      measuring phosphatase activity.

PMID- 4357145
TI  - Improved automated determination of bound N-acetylneuraminic acid in serum.

PMID- 4357147
TI  - Ferric chloride-impregnated silica gel for thin-layer chromatography of steroids.

PMID- 4357148
TI  - [Superficial spreading melanoma. Paget's melanoma].

PMID- 4357149
TI  - [Adrenocortical insufficiency as a result of isolated corticotropin-releasing
      hormone (CRH) deficiency (author's transl)].

PMID- 4357150
TI  - [Letter: Hypertensin].

PMID- 4357152
TI  - Proceedings: The association of a specific skin lesion with islet-cell tumours of
      the pancreas.

PMID- 4357151
TI  - Proceedings: Comparison between collagenase activity in rectal biopsies and
      plasma carcinoembryonic antigen (CEA) levels in patients with carcinoma of the
      colon and rectum.

PMID- 4357153
TI  - Contraction of isolated human breast cutaneous vascular smooth muscle.

PMID- 4357154
TI  - Wart-associated antigens. I. Isolation of tissue antigens using antibody
      immunoadsorbents.

PMID- 4357155
TI  - Wart-associated antigens. II. Human immunity to viral structural proteins.

PMID- 4357157
TI  - Ultrastructural studies of olivopontocerebellar atrophy.

PMID- 4357156
TI  - Adherence of platelets to a collagen-coated surface: development of a
      quantitative method.

PMID- 4357158
TI  - Primary brain and spinal cord tumors induced by human adenovirus type 12 in
      hamsters.

PMID- 4357159
TI  - Microchemical studies of lipids, proteins and nucleic acids in polyoma virus
      transformed hamster astroglia.

PMID- 4357160
TI  - Glomus tumors in the middle ear. I. An analysis of 46 patients.

PMID- 4357162
TI  - The influence of temperature and fibril stability on degradation of cartilage
      collagen by rheumatoid synovial collagenase.

PMID- 4357161
TI  - Surgically confirmed gallbladder disease, venous thromboembolism, and breast
      tumors in relation to postmenopausal estrogen therapy. A report from the Boston
      Collaborative Drug Surveillance Program, Boston University Medical Center.

PMID- 4357163
TI  - Phospholipids in biology and medicine (first of two parts).

PMID- 4357164
TI  - Editorial: Collegenase, cartilage and cortisol.

PMID- 4357165
TI  - A novel substituted guanidine with high activity in vitro against rhinoviruses.

PMID- 4357166
TI  - Histamine H1 and H2-receptors at a ganglionic synapse.

PMID- 4357167
TI  - Synthesis of poly(A) in vitro by purified virions of vesicular stomatitis virus.

PMID- 4357168
TI  - Affinity of 253Einsteinium for tumour tissue.

PMID- 4357169
TI  - Morphological transformation of enucleated Chinese hamster ovary cells by
      dibutyryl adenosine 3',5'-monophosphate and hormones.

PMID- 4357170
TI  - An immunological study of human brain tumors concerning the brain specific
      protein S-100 and 14.3.2.

PMID- 4357171
TI  - Acrylamide neuropathy in rats. An electron microscopic study of degeneration and
      regeneration.

PMID- 4357172
TI  - Peripheral neuropathy in ageing rats fed clioquinol and a maize diet.

PMID- 4357174
TI  - The hypocalcemic response to protamine as a measure of bone resorption.

PMID- 4357173
TI  - The effect of perinatal undernutrition on perineurial diffusion barrier to
      exogenous protein. An experimental study on rat sciatic nerve.

PMID- 4357175
TI  - Bovine mycoplasmas: cultural and biochemical studies. II.

PMID- 4357176
TI  - Fine structural alterations of bovine peripheral pulmonary arteries in hypoxia
      induced hypertension.
AB  - Cellular alterations of the distal bovine pulmonary arteries in hypoxia-induced
      pulmonary hypertension were studied. These lesions were related to pulmonary
      hemodynamic changes and contrasted to the cellular response observed in
      hyperkinetic pulmonary and systemic hypertension as well as other forms of
      vascular injury. Medial thickening and mild adventitial proliferation with an
      absence of intimal proliferative lesions related to a progressive increase in
      mean pulmonary arterial pressure and pulmonary vascular resistance were observed.
      Smooth muscle and endothelial cells exhibited distinct degenerative alterations
      in response to the maintained hypertensive state resulting from the lowered
      alveolar oxygen tension.

PMID- 4357177
TI  - Collagen-proteoglycan relationships in epiphyseal cartilage.
AB  - Columnar and hypertrophic zones of calf scapular cartilage were studied before
      and after extraction with 3 M guanidinium chloride (GuCl) and digestion with
      enzymes which degrade various components of the extracellular matrix. Morphologic
      and chemical analysis suggests that there are at least two anatomic pools of
      proteoglycan in this tissue. One, which resides between collagen fibrils, is
      extractable with GuCl. Another appears attached to collagen by strong bonds and
      is apparently not extractable with GuCl. This type of collagen-proteoglycan
      relationship is possibly restricted to epiphyseal cartilage. The morphology of
      the lacuna is different in the columnar and hypertrophic zones. Proteoglycans in
      the distal hypertrophic zone are less resistant to GuCl extraction.

PMID- 4357178
TI  - Endocrine and immunologic studies in breast cancer.

PMID- 4357179
TI  - [Experimental hepatography in rats by selective intra-arterial injection of an
      iodo-lipid emulsion: effect of particle size].

PMID- 4357180
TI  - Inactivation of Herpesvirus hominis types 1 and 2 by silver nitrate in vitro and
      in vivo.
AB  - Herpes simplex virus (HSV) types 1 and 2 (two strains each) were inactivated at
      different rates in vitro by 40 muM AgNO(3). The inactivation of HSV type 1
      strains was virtually complete in 10 to 15 min, whereas almost half of the
      infectivity of HSV type 2 strains survived this exposure. One strain of type 1
      inoculated into rabbit eyes was almost completely inactivated by 1% AgNO(3)
      solution dropped into the eye 20 min later, so that there was markedly reduced
      viral replication and less corneal herpetic disease. One strain of HSV type 2 in
      the rabbit eye was not effectively inactivated by 1% AgNO(3). From these results,
      it seems likely that AgNO(3) instillation into the eyes of a newborn who has
      passed through a birth canal infected with HSV might prevent eye infection with
      HSV type 1 but not with type 2. The greater resistance of HSV type 2 strains to
      chemical inactivation in vitro and in vivo may be of medical concern.

PMID- 4357181
TI  - Antiviral effects of aphidicolin, a new antibiotic produced by Cephalosporium
      aphidicola.
AB  - Aphidicolin is an antibiotic of novel structure produced by the mold
      Cephalosporium aphidicola. It is a potent inhibitor of cellular deoxyribonucleic
      acid synthesis, and it also strongly inhibits the growth of herpes simplex virus
      both in tissue culture and in the rabbit eye. Aphidicolin is active against
      iododeoxyuridine-resistant herpes virus, and does not itself readily induce the
      formation of drug-resistant strains of herpesvirus.

PMID- 4357182
TI  - Serum and urinary concentrations of cyclacillin in humans.
AB  - Cyclacillin is a semisynthetic penicillin produced from the penicillin nucleus (6
      aminopenicillanic acid) by acylation with 1-aminohexanecarboxylic acid. The
      absorption and excretion characteristics of cyclacillin were defined in one
      completely randomized and three three-way crossover experiments. Mean peak serum
      cyclacillin levels appeared earlier and were fivefold higher than those obtained
      with equal doses of ampicillin. High serum cyclacillin concentrations were
      reached at 0.5 h and by 2 h were lower than ampicillin. Serum ampicillin
      concentrations peaked at 1.5 h, remaining slightly higher than those for
      cyclacillin for the next 4.5 h. The mean area for the cyclacillin curve was
      significantly superior to either of the ampicillin formulations. Mean serum
      concentrations of cyclacillin exhibited a smooth dose-response, approximately
      doubling in each instance as the dose was doubled from 250 to 500 and from 500 to
      1,000 mg. High concentrations of cyclacillin were also demonstrated in urine.
      Neither ratio of drug to metabolite in the urine nor the percent of excretion was
      significantly affected by the dose level. Sixty-seven percent of the drug was
      excreted unchanged, and 17% was excreted as penicilloic acid, with most of the
      excretion occurring within 6 h of administration. In subjects given 500 mg of
      cyclacillin (four times daily) for 6 days, 2% of the drug was excreted as 1
      aminocyclohexanecarboxylic acid, and approximately 55% (24 to 91%) was unchanged.
      Neither formation nor excretion of the former was sex dependent.

PMID- 4357184
TI  - Selective cytotoxicity of peritoneal leucocytes for neoplastic cells.

PMID- 4357183
TI  - [Enzyme histochemistry of malignant melanoma. Investigations on primary tumors
      and metastases (author's transl)].

PMID- 4357185
TI  - Cellular events in protein tolerant inbred rats. I. The fate of thoracic duct
      lymphocytes and memory cells during tolerance induction to human serum albumin.

PMID- 4357186
TI  - Estrogen-sensitive cells. Hormone receptors in tumors and cells in culture.

PMID- 4357187
TI  - Cyclic AMP, pattern formation and movement in the slime mould, Dictyostelium
      discoideum.

PMID- 4357188
TI  - Inhibition of cyclic 3',5'-nucleotide phosphodiesterase activity by diuretics and
      other agents.

PMID- 4357189
TI  - Lag period of action of 25-hydroxycholecalciferol on bone collagen metabolism in
      vitamin D deficient rats.

PMID- 4357190
TI  - Effect of various prostaglandins and serotonin on protein secretion from rat
      exocrine pancreas.

PMID- 4357191
TI  - The rate limiting control of enzymes monoamine oxidase and catechol-O-methyl
      transferase in the foetus and the adult by adreno-cortical hormones.

PMID- 4357192
TI  - Immunohistochemical demonstration of corticotrophic cells concentrated in the
      rostral zone of the pars intermedia of the mouse hypophysis.

PMID- 4357193
TI  - Detection of encephalomyocarditis virus infection in animal cells by gas liquid
      chromatography.

PMID- 4357194
TI  - [Properties and physiological role of protein specifically binding riboflavin.
      II. Mechanism of flavin-protein interaction].

PMID- 4357195
TI  - Influence of suramin on activity of some hydrolytic and oxidative enzymes of
      pseudoeosinophilic (heterophil) peripheral blood granulocytes in rabbits.

PMID- 4357196
TI  - Modification of the acute toxicity of mutagenic and carcinogenic chemicals in the
      mouse by prefeeding with antioxidants.

PMID- 4357198
TI  - Virus-induced premature chromosome condensation (PCC) in single cells and G-bands
      of PCC-chromatin.

PMID- 4357197
TI  - Ultrastructure of cytoplasmic hyaline inclusions in a case of human
      hepatocarcinoma.

PMID- 4357200
TI  - Presynaptic inhibition of adrenergic motor transmission in rat anococcygeus
      muscle by D-lysergic acid diethylamide (LSD).

PMID- 4357199
TI  - Cortical pyramidal tract interneurones and their sensitivity to L-glutamic acid.
AB  - 1. Pyramidal tract interneurones, defined as neurones which are activated
      synaptically as a result of pyramidal tract stimulation, have been identified in
      the rat cerebral cortex. The number of evoked spikes depended upon stimulus
      strength, and stimulation in a specific thalamic nucleus produced a burst of
      activity lasting for up to 1 sec.2. These cells are readily excited by a brief
      (50 msec) pulse of glutamate applied by micro-iontophoresis. Other, unidentified
      cells are not so responsive.3. Synaptically evoked spikes resulting from
      pyramidal tract stimulation can be blocked by the iontophoretic and I.P.
      administration of substances shown to antagonize glutamate excitation of cells.4.
      The results support suggestions that glutamic acid is a neurotransmitter in the
      cerebral cortex. The evidence presented further indicates that glutamic acid
      could be the transmitter released by the pyramidal tract.

PMID- 4357201
TI  - The effect of a bradykinin potentiating nonapeptide (BPP9a) on prolonged
      haemorrhagic shock in dogs.

PMID- 4357203
TI  - [Adenocarcinoma of the bladder].

PMID- 4357202
TI  - Involvement of calcium in the inhibitory effects of putative transmitter
      substances in the cerebral cortex.

PMID- 4357204
TI  - Effect of vitamin D3 and other factors on phosphate absorption by the chick.

PMID- 4357205
TI  - Activation of prolyl hydroxylase by ascorbic acid.

PMID- 4357206
TI  - Use of cross-finger flap for treatment of congenital broad constricting bands of
      the fingers.

PMID- 4357207
TI  - [Australia-antigen in chronic hepatic pathology (author's transl)].

PMID- 4357208
TI  - Intramolecular nucleophilic attack of an ureido group on the beta-lactam carbonyl
      moiety of penicillins.

PMID- 4357209
TI  - Different properties of microsomal UDP-glucuronyltransferase in buffalo rat liver
      and a clonal strain of rat hepatoma cells derived from the same rat strain.

PMID- 4357210
TI  - The Russell-Silver syndrome: a nine-year follow-up.

PMID- 4357211
TI  - Menetrier disease and cytomegalovirus infection in childhood.

PMID- 4357212
TI  - Multiple joint dislocations and peculiar facies.

PMID- 4357213
TI  - Letter: Cytomegalovirus infection and toxoplasma.

PMID- 4357214
TI  - Current concepts in management of periampullary carcinoma.

PMID- 4357215
TI  - Lymphocytes in some hypereosinophilic states.

PMID- 4357216
TI  - Neuromuscular physiology of wound botulism.

PMID- 4357217
TI  - Unusual complications of iophendylate injection myelography. Report of a case and
      review.

PMID- 4357218
TI  - Eye disease among American Indians of the Southwest. II. Trachoma.

PMID- 4357219
TI  - Comparison of types 1 and 2 Herpesvirus hominis infection of rabbit eyes. I.
      Clinical manifestations.

PMID- 4357220
TI  - Comparison of types 1 and 2 Herpesvirus hominis infection of rabbit eyes. II.
      Histopathologic and virologic studies.

PMID- 4357221
TI  - Treatment of neuropathic conditions of the foot and ankle with a patellar-tendon
      bearing brace.

PMID- 4357222
TI  - Effect of propranolol on cyclic AMP excretion and plasma renin activity in labile
      essentrial hypertension.
AB  - Labile hypertension is often associated with elevated cardiac output, increased
      plasma renin activity (PRA) and urinary cyclic AMP excretion in response to
      upright posture and to isoproterenol. The beta-blocking agent propranolol was
      demonstrated to be an effective therapeutic agent in this condition. The effect
      of posture on cyclic AMP, PRA, pulse rate and blood pressure was therefore
      studied during the administration of propranolol and a placebo in patients with
      labile hypertension. With the patient on placebo, upright posture induced an
      increase in pulse rate, cyclic AMP excretion and PRA. Propranolol administration
      decreased the recumbent and upright blood pressures, pulse rate and PRA. Cyclic
      AMP excretion remained unchanged in the recumbent position but the postural
      increase was abolished. No appreciable changes in catecholamine excretion
      occurred during propranolol administration. Propranolol normalizes some humoral
      as well as hemodynamic abnormalities of labile hypertension and therefore may be
      of benefit in long-term treatment and possibly also in the prevention of stable
      hypertension.

PMID- 4357224
TI  - Generation of angiotensin II at peripheral vascular level: studies using
      angiotensin II antisera.

PMID- 4357223
TI  - Plasma lipid and lipoprotein abnormalities in patients with malabsorption.

PMID- 4357225
TI  - Effects of midbrain tegmental lesions on sleep and regional brain serotonin and
      norepinephrine levels in cats.

PMID- 4357226
TI  - Glomerular basement membrane antigens of Masugi nephritis.

PMID- 4357228
TI  - Proceedings: The correlation between redox bioassay and radioimmunoassay for
      adrenocorticotrophin during insulin hypoglycaemia.

PMID- 4357229
TI  - Proceedings: Measurement of plasma adrenocorticotrophin levels in normal and
      hypopituitary subjects by redox bioassay.

PMID- 4357227
TI  - Pulp reaction to a resin-bonded quartz composite material.

PMID- 4357230
TI  - Proceedings: Adrenocorticotrophin (ACTH) and beta-melanocyte-stimulating hormone
      peptides in tumours associated with the ectopic ACTH syndrome.

PMID- 4357231
TI  - Proceedings: Blueprints for the solution of three endocrinological enigmas. The
      Sir Henry Dale Lecture for 1973.

PMID- 4357232
TI  - Proceedings: Effects in vitro of cytoplasmic and nuclear 5alpha
      dihydrotestosterone-receptor complexes on prostatic RNA polymerase activities.

PMID- 4357233
TI  - Proceedings: Calcium dependent release of hypophysiotropic substances from nerve
      endings (synaptosomes) isolated from the hypothalamus.

PMID- 4357234
TI  - Proceedings: The role of cyclic AMP in the action of androgens on rat ventral
      prostate gland.

PMID- 4357235
TI  - Proceedings: A comparison of the effects of alpha 1-24 adrenocorticotrophin Zn
      (Tetracosactrin depot) and of substituted alpha 1-18 adrenocorticotrophin on
      adrenocortical function in normal subjects.

PMID- 4357236
TI  - Proceedings: L-DOPA as a test of anterior pituitary function.

PMID- 4357237
TI  - Proceedings: A simple enzymic method for the radio-iodination of
      adrenocorticotrophic hormone.

PMID- 4357238
TI  - Proceedings: Effect of protein hormones on the biosynthesis of
      dehydroepiandrosterone sulphate by human foetal adrenal tissue in vitro.

PMID- 4357239
TI  - [Enterotoxemia in pigs and cattle due to Clostridium welchii type A].

PMID- 4357240
TI  - The co-existence of parathyroid and thyroid disease. I. Primary
      hyperparathyroidism and thyroid carcinoma.

PMID- 4357241
TI  - Angiographic diagnosis of tumors producing hypoglycemia.

PMID- 4357242
TI  - Electrical stimulation for relief of pain from chronic nerve injury.

PMID- 4357243
TI  - Ther reversal of experimental vasospasm by dibutyryl-3',5'-adenosine
      monophosphate.

PMID- 4357244
TI  - [Cytochemistry of the leukocyte (author's transl)].

PMID- 4357245
TI  - [Recent cytological studies in gynecological field (author's transl)].

PMID- 4357246
TI  - Glucagon stimulation of hepatic gluconeogenesis in rats fed a high-protein,
      carbohydrate-free diet.

PMID- 4357247
TI  - Hormone dependence in breast cancer.

PMID- 4357248
TI  - Scar cancer of lung complicating rheumatoid lung disease.

PMID- 4357249
TI  - Differences between cytoplasmic glucocorticoid-binding proteins shown by
      heterogeneity of nuclear acceptor sites.

PMID- 4357250
TI  - Calcifying mucin producing adenocarcinoma of stomach.

PMID- 4357251
TI  - Proceedings: Lichen striatus.

PMID- 4357253
TI  - Proton radiography in the diagnosis of breast carcinoma.

PMID- 4357252
TI  - Computerized axial tomography with the EMI scanner.

PMID- 4357254
TI  - Viral infections and the surgical patient.

PMID- 4357255
TI  - Surgical experience with malignant tumors of the ampulla of vater and duodenum.

PMID- 4357256
TI  - The significance of mammography, galactography, and pneumocystography in
      detecting occult carcinomas of the breast.

PMID- 4357258
TI  - Letter: Double-blind trial for treatment of herpes iritis and stromal disease.

PMID- 4357257
TI  - Induction of ovulation in patients following removal of a pituitary adenoma.

PMID- 4357259
TI  - A comparative quality survey of five common market foods in low and high income
      economic areas.

PMID- 4357260
TI  - Suxamethonium hyperkalaemia in uraemic neuropathy.

PMID- 4357262
TI  - Pulmonary function in granite shed workers of Vermont.

PMID- 4357261
TI  - Dust exposure in the Vermont granite sheds.

PMID- 4357263
TI  - Pulmonary function and roentgenographic changes in granite dust exposure.

PMID- 4357264
TI  - Prostaglandins: their actions on the gastrointestinal tract.

PMID- 4357266
TI  - Substances that inhibit the actions of prostaglandins.

PMID- 4357265
TI  - Prostaglandins and the central nervous system.

PMID- 4357267
TI  - Biological aspects of prostaglandins.

PMID- 4357268
TI  - Prostaglandins in hematology.

PMID- 4357269
TI  - Effects of cobalt on the renal erythropoietic factor and kidney hydrolase
      activity in the rat.

PMID- 4357270
TI  - Enhanced binding of neuraminidase-treated sheep erythrocytes to human T
      lymphocytes.

PMID- 4357271
TI  - A thin-layer gel filtration assay of cytoplasmic oestrogen receptors. A possible
      screening method for hormone dependent tumours.
AB  - A thin-layer gel filtration system for the assay of oestrogen receptors in target
      organ tissue samples as small as 50 mg is presented and compared with the sucrose
      gradient centrifugation method. Only specific high-affinity binding of
      [(3)H]17beta-oestradiol to endometrial cytosol has been observed with the thin
      layer gel filtration assay, despite the presence of relatively high levels of
      nonspecific binding components. The system could be adapted to the clinical
      determination of oestrogen receptor content in biopsy material from mammary and
      endometrial tumours and would be of value in predicting hormone dependency.

PMID- 4357273
TI  - Early detection of lung cancer. Clinical conference from the University of Iowa
      College of Medicine.

PMID- 4357272
TI  - A study of electron spin resonance spectra of whole blood from normal and tumour
      bearing patients.
AB  - Electron spin resonance spectra have been obtained from samples of frozen whole
      blood or separated blood cells and plasma. Blood samples were obtained from human
      controls having no diagnosed malignancy and from patients with a variety of
      benign and malignant tumours.The characteristic spectrum from control blood shows
      two main lines with g values of 4.2 and 2.049. Several smaller lines can also be
      observed. The line at g = 2.049 may be due to the copper protein ceruloplasmin.
      Although no qualitative differences could be found between the spectra from
      controls and cancer patients, samples from patients with certain types of tumour
      showed a significant increase in size of the g = 2.049 signal above control
      values. This was most noticeably the case with Hodgkin's disease and to a lesser
      extent with cancers of the breast. Squamous cell carcinomata, taken as a group,
      did not show an elevation in average size of the g = 2.049 signal. In this latter
      group, however, there were some indications that the effects of chemotherapeutic
      treatment could be followed during the early stages of such treatment. Examples
      are given in which onset of treatment with various cytotoxic agents was
      associated with reduction in size of the g = 2.049 signal.

PMID- 4357274
TI  - Sleep recordings from limbic structures in man.

PMID- 4357275
TI  - Effect of volume expansion by hyperosmolar and hyperoncotic solutions under
      constant infusion of angiotensin II on plasma aldosterone in man and its
      counterbalance by potassium administration.

PMID- 4357276
TI  - Male sterility induced by ethanol injection into the vas deferens.

PMID- 4357278
TI  - Occurrence of HL-A antibodies in sera of sterile women.

PMID- 4357277
TI  - The menstrual cycle in women treated with d-norgestrel 37.5 micrograms in
      continuous administration.

PMID- 4357279
TI  - Demonstration of HL-A antigens, "species", and "semen"-specific antigens on human
      spermatozoa. A study by immunofluorescence and immunoelectron microscopy.

PMID- 4357280
TI  - Serious pelvic infections associated with intrauterine contraceptive device.

PMID- 4357281
TI  - The effect of a continuous low dose progestin on tubal and uterine motility.

PMID- 4357282
TI  - Tubal occlusion by electrocoagulation under hysteroscopy. A preliminary report.

PMID- 4357283
TI  - The correlation of clinical and morphological parameters in induced ovulatory
      cycles in the human.

PMID- 4357284
TI  - Occurrence of spontaneous second pregnancy after delivery of conceptions
      resulting from ovulation induced by various therapeutic modalities.

PMID- 4357285
TI  - The TCu-300 IUD. A preliminary report.

PMID- 4357286
TI  - Efforts to relate spermatozoan motility to fertilizing capacity.

PMID- 4357287
TI  - Hepatitis-associated antigen in chronic liver diseases in Upper-Egypt.

PMID- 4357289
TI  - Plasma renin activity: method of measurement and significance in the diagnosis of
      hypertension.

PMID- 4357288
TI  - Amebiasis in the tropics. (A historical review).

PMID- 4357290
TI  - Tissue culture studies of children's tumours.

PMID- 4357291
TI  - Adrenocortical cell deletion: the role of ACTH.

PMID- 4357293
TI  - Age-dependent differences in the binding of (131-I) LH by rat testis homogenates.

PMID- 4357294
TI  - Proceedings: Relation of cyclic AMP to sperm motility.

PMID- 4357292
TI  - Binding of radioiodinated human placental lactogen to buffalo corpus luteum in
      vitro.

PMID- 4357296
TI  - Proceedings: Oestrogen binding to rabbit blastocysts and its possible role in
      implantation.

PMID- 4357295
TI  - Proceedings: Regulation of steroid secretion in sheep ovarian follicles.

PMID- 4357297
TI  - Letter: Segmental portal hypertension and islet cell adenoma of the pancreas.

PMID- 4357299
TI  - [Innervation of the varicose communicant veins of the lower extremities].

PMID- 4357298
TI  - Acute respiratory illness in an American community. The Tecumseh study.

PMID- 4357300
TI  - [Antibodies to some viruses in laboratory monkeys].

PMID- 4357302
TI  - Chemically induced reversion and suppression of methionine-I alleles of
      Neurospora crassa.

PMID- 4357301
TI  - Surgical treatment of lung cancer. Five-year follow-up of 266 patients.

PMID- 4357303
TI  - A yeast strain for visual screening for the two reciprocal products of mitotic
      crossing over.

PMID- 4357304
TI  - Liver microsomal assays for evaluating the metabolism of environmental mutagens.

PMID- 4357305
TI  - Analysis of virus replication in ageing human fibroblast cultures.

PMID- 4357306
TI  - Effect of neuraminidase pretreatment on the susceptibility of normal and
      transformed mammalian cells to bovine enterovirus 261.

PMID- 4357307
TI  - Prolactin secretion is specifically inhibited by nickel.

PMID- 4357308
TI  - Induction of Epstein-Barr virus-related membrane antigens by 5-iododeoxyuridine
      in non-producer human lymphoblastoid cells.

PMID- 4357309
TI  - Immunofluorescent antigen associated with Epstein-Barr virus induced by 5
      Iododeoxyuridine.

PMID- 4357310
TI  - Theta alloantigen on mouse and rat fibroblasts.

PMID- 4357311
TI  - Central corticotropin inhibition by arginine vasotocin in the mouse.

PMID- 4357312
TI  - [Histochemical picture of rat's brain in experimental acute carbon monoxide
      poisoning].

PMID- 4357313
TI  - [Ontogeny and phylogeny of some proteins and isoenzymes (author's transl)].

PMID- 4357314
TI  - [Biological role of nonhistone proteins of chromatin (author's transl)].

PMID- 4357315
TI  - Localization of nucleoside diphosphatase in the onion root tip.

PMID- 4357316
TI  - Radiology of genitourinary trauma.

PMID- 4357317
TI  - Concomitant infection with Entamoeba histolytica and two Shigella strains.

PMID- 4357318
TI  - Serological evidence of respiratory syncytial virus infection in sheep.

PMID- 4357319
TI  - Biolobical activity of corticotrophin peptides with homo-arginine, lysine or
      ornithine substituted for arginine in position 8.

PMID- 4357320
TI  - Somatotrophic and corticotrophic functions in primary hypothyroidism before and
      after thyroxine treatment.

PMID- 4357322
TI  - Streptozotocin treatment of tumor hypoglycemia due to primary livercell
      carcinoma.

PMID- 4357321
TI  - Plasma concentration and protein binding of oestriol and its conjugates in
      pregnancy.

PMID- 4357323
TI  - Morphometric study on the distribution of liver necrosis in experimental murine
      hepatitis by MHV-3 virus.

PMID- 4357324
TI  - Alteration of enzyme histochemistry in liver cells attacked by human hepatitis
      virus.

PMID- 4357325
TI  - Postmenopausal osteoporosis.

PMID- 4357327
TI  - Adrenal steroid secretion in the rabbit: sodium depletion, angiotensin II, and
      ACTH.

PMID- 4357326
TI  - Response of mitochondrial enzymes to decreased muscular activity.

PMID- 4357328
TI  - Canine cerebrovascular response to nitroglycerin, acetylcholine, 5
      hydroxytryptamine, and angiotensin.

PMID- 4357329
TI  - Gluconeogenesis in a carnivorous bird (black vulture).

PMID- 4357330
TI  - Gout and its relation to lipid metabolism. I. Serum uric acid, lipid, and
      lipoprotein levels in gout.

PMID- 4357331
TI  - Gout and its relation to lipid metabolism. II. Correlations between uric acid,
      lipid, and lipoprotein levels in gout.

PMID- 4357333
TI  - Proceedings: Effect of corticotrophin and oral corticosteroids on nocturnally
      released growth hormone.

PMID- 4357332
TI  - Ultrastructural aspects of lymphoreticular cells in rheumatoid synovium.

PMID- 4357334
TI  - Proceedings: A re-examination of the hypoglycaemia-induced "stress" response of
      the hypothalamo-pituitary-adrenal axis in patients with rheumatoid arthritis on
      long-term adrenocorticotrophin (ACTH) therapy.

PMID- 4357335
TI  - Value of serum gastrin in the diagnosis of the Zollinger-Ellison syndrome.

PMID- 4357336
TI  - Formation of enolpyruvate in the phosphoenolpyruvate carboxytransphosphorylase
      reaction.

PMID- 4357337
TI  - Phosphoenolpyruvate carboxytransphosphorylase. An investigation of the mechanism
      with 18 O.

PMID- 4357338
TI  - Synthesis and biochemical studies of various 8-substituted derivatives of
      guanosine 3',5'-cyclic phosphate, inosine 3',5'-cyclic phosphate, and xanthosine
      3',5'-cyclic phosphate.

PMID- 4357339
TI  - Structures of oligosaccharides produced by base--borohydride degradation of human
      ovarian cyst blood group H, Le-b and Le-a active glycoproteins.

PMID- 4357340
TI  - Lateral diffusion, protein mobility, and phase transitions in Escherichia coli
      membranes. A spin label study.

PMID- 4357341
TI  - Comparative electron cytochemical studies of presynaptic and other neuronal
      mitochondria.

PMID- 4357343
TI  - Acetylcholine metabolism and release at the nerve-electroplaque junction.

PMID- 4357342
TI  - Prostaglandin as a tool for local control of transmitter release from sympathetic
      nerves.

PMID- 4357344
TI  - Consequences of denervation on the distribution of the cholinergic (nicotinic)
      receptor sites from Electrophorus electricus revealed by high resolution
      autoradiography.

PMID- 4357345
TI  - Role of amino acids and peptides in synaptic transmission.

PMID- 4357347
TI  - Genetic factors in the natural history of murine leukemia virus infection: G. H.
      A. Clowes Memorial Lecture.

PMID- 4357346
TI  - Nervous tissue culture--a model to study action and uptake of putative
      neurotransmitters such as amino acids.

PMID- 4357348
TI  - Histochemical studies on nuclease activity and neoplastic transformation in rat
      liver during diethylnitrosamine carcinogenesis.

PMID- 4357349
TI  - Metastasis in a transplantable mammotrophic pituitary tumor.

PMID- 4357350
TI  - Nonfibroblastic origin of foreign body sarcomas implicated by histological and
      electron microscopic studies.

PMID- 4357351
TI  - Transfer of tumor-specific delayed hypersensitivity in vitro to normal guinea pig
      peritoneal exudate cells using RNA extracts from sensitized lymphoid tissues.

PMID- 4357352
TI  - Experimental studies bearing on the question of retrograde spread of Hodgkin's
      disease via the thoracic duct.

PMID- 4357353
TI  - Surface particles on leukemic lymphocytes in humans.

PMID- 4357354
TI  - Effect of arginine on the incorporation of 32P into rat liver and Novikoff
      hepatoma cytosol proteins.

PMID- 4357355
TI  - Establishment and characterization of a cloned line of C3H mouse embryo cells
      sensitive to postconfluence inhibition of division.

PMID- 4357356
TI  - A study of the macromolecular binding of 67Ga in normal and malignant animal
      tissues.

PMID- 4357358
TI  - Enhancement of lymphoma cell immunogenicity by infection with nononcogenic virus.

PMID- 4357359
TI  - Host age dependency of regression of Rous sarcomas of chickens.

PMID- 4357357
TI  - Cyclic adenosine 3',5'-monophosphate and cell volume.

PMID- 4357360
TI  - Similarity of ribosomal and ribosomal precursor RNA's from rat liver and the
      Novikoff ascites hepatoma.

PMID- 4357361
TI  - Characterization of primary hepatocellular carcinomas and initial transplant
      generations.

PMID- 4357362
TI  - A survey of blood group, serum protein and red cell enzyme polymorphisms in the
      Orkney islands.

PMID- 4357363
TI  - Production of Sendai virus for cell fusion.

PMID- 4357364
TI  - Studies of effects of cyclic adenosine 3',5'-monophosphate in regulation of human
      hemopoiesis in vitro.

PMID- 4357365
TI  - Factors determining the site of synthesis of poliovirus proteins: the early
      attachment of virus particles to endoplasmic membranes.

PMID- 4357366
TI  - A rapidly sedimenting fraction of rat liver endoplasmic reticulum.

PMID- 4357367
TI  - Effects of ethidium bromide on growth, chlorophyll synthesis, ultrastructure and
      mitochondrial DNA in green and bleached mutant, Euglena gracilis.

PMID- 4357368
TI  - Ross River virus replication in cultured mosquito and mammalian cells: virus
      growth and correlated ultrastructural changes.

PMID- 4357369
TI  - The interaction of herpes simplex virus with cultures of peripheral nervous
      tissue: an electron microscopic study.

PMID- 4357370
TI  - Induction of interferon in chick cells by polyoma virus.

PMID- 4357371
TI  - Surface antigen on hamster cells transformed in vitro by two strains of Rous
      sarcoma virus.

PMID- 4357372
TI  - Infection, haemorrhage and death of chick embryos after inoculation of herpes
      simplex virus type 2 on to the chorioallantoic membrane.

PMID- 4357373
TI  - Interferon bioassay: reduction in yield of myxovirus neuraminidases.

PMID- 4357374
TI  - The effect of frog virus 3 on the biological activity of various RNA viruses.

PMID- 4357376
TI  - Size differences in the ribonucleic acids of feline leukaemia viruses.

PMID- 4357375
TI  - Interferon induction site: poly IC on solid substrate carriers.

PMID- 4357377
TI  - Transfection of chicken fibroblasts with single exposure to DNA from virogenic
      mammalian cells.

PMID- 4357378
TI  - Quantitative studies of oncornaviruses in thin sections.

PMID- 4357379
TI  - The formation of poliovirus particles in association with the RNA replication
      complexes.

PMID- 4357380
TI  - Reflux esophagitis. A comparison of old and new medical management.

PMID- 4357381
TI  - Ceruminoma of external ear. A clinico-pathological study of three cases.

PMID- 4357382
TI  - Initial steps in the de novo pyrimidine biosynthesis in Ascaris suum.

PMID- 4357383
TI  - ATP as a nerve transmitter substance.

PMID- 4357384
TI  - Chemotaxis, signal relaying and aggregation morphology.

PMID- 4357385
TI  - Sexual maturation in juvenile hypothyroidism.

PMID- 4357387
TI  - 5-Methyltryptophan resistance mutations in Escherichia coli K-12. Mutagenic
      activity of monofunctional alkylating agents including organophosphorus
      insecticides.

PMID- 4357386
TI  - The effect of caffeine on chromosomes of human lymphocytes: a search for the
      mechanism of action.

PMID- 4357388
TI  - Emerging concepts of platelet function.

PMID- 4357389
TI  - DNA sequence restricted by restriction endonuclease AP from Haemophilus
      aphirophilus.

PMID- 4357390
TI  - Human lymphoid cell transformation by Epstein-Barr virus.

PMID- 4357391
TI  - Antiviral and non-antiviral activity of highly purified interferon.

PMID- 4357392
TI  - Hormone-induced desensitisation of hormonal control of cyclic AMP levels in human
      diploid fibroblasts.

PMID- 4357393
TI  - HCG-receptor present in the gonadotrophin insensitive Leydig cell of the immature
      rat.

PMID- 4357394
TI  - Studies on the active principle of Solanum malacoxylon.

PMID- 4357396
TI  - Low density lipoproteins of chicken, turkey and quail egg yolk.

PMID- 4357397
TI  - Effect of temperature on inhibition of chicken liver fructose diphosphatase by
      adenosine 5'-monophosphate.

PMID- 4357395
TI  - [Vitamin D metabolism and its role in the light of new experimental
      achievements].

PMID- 4357398
TI  - Toxicity of various selenium derivatives to chick embryos.

PMID- 4357400
TI  - Reversibility of inhibition of chicken liver fructose diphosphatase by adenosine
      5'-monophosphate.

PMID- 4357399
TI  - Some physiological responses of turkeys selected for high and low adrenal
      response to cold stress.

PMID- 4357402
TI  - Skeletal development of Finnish children in the light of hand-wrist
      roentgenograms.

PMID- 4357401
TI  - Protocollagen proline hydroxylase activity in human gingiva.

PMID- 4357403
TI  - Flunitrazepam (Ro 5-4200) and sleep cycle in normal subjects.

PMID- 4357404
TI  - Stimulation of cyclic AMP in the isolated perfused rat lung.

PMID- 4357405
TI  - Plumbism: adaptive changes in hepatic and renal metabolism.

PMID- 4357407
TI  - Peripheral nerve regeneration; sudomotor print test with iodine impregnated
      paper.

PMID- 4357406
TI  - Advanced lung cancer: A clinical trial of radiotherapy plus two drug combination
      regimens.

PMID- 4357408
TI  - Paradoxical bradycardia during REM sleep in periodic catatonia.

PMID- 4357409
TI  - [Role of the kininogen-kinin system in the pathogenesis of inflammatory diseases
      of the female sex organs].

PMID- 4357410
TI  - [Diagnosis of viral and staphylococcal endocervicitis].

PMID- 4357411
TI  - [Genital herpetic infection (a review of the literature)].

PMID- 4357412
TI  - [Krukenberg's cancer according to data from a gynecology department for a 10-year
      period].

PMID- 4357413
TI  - Food zealotry and youth: new dilemmas for professionals.

PMID- 4357415
TI  - Editorial views: Non-respiratory functions of the lung.

PMID- 4357414
TI  - Development of an abortion service in a large municipal hospital. Review of the
      first year's experience.

PMID- 4357416
TI  - Anterior displacement of the inferior vena cava by hepatic masses.

PMID- 4357417
TI  - Granular cell myoblastoma of the esophagus. Incidence and surgical treatment.

PMID- 4357418
TI  - Diagnosis of tracheal tumors.

PMID- 4357419
TI  - The ocular fixation index.

PMID- 4357420
TI  - Central vestibular diagnosis. Neurologic examination.

PMID- 4357421
TI  - Measurement of the oxidation reduction potential of the EPR detectable active
      centre of the molybdenum iron protein of Chromatium nitrogenase.

PMID- 4357423
TI  - Polyamines and tumor cells: effect of transformation of chick embryo fibroblasts
      by Rous sarcoma virus on polyamine levels.

PMID- 4357422
TI  - Genetic regulation of a constitutive operon in E. coli B-r.

PMID- 4357424
TI  - Effect of thyroid hormone analogues on the displacement of 125I-L
      triiodothyronine from hepatic and heart nuclei in vivo: possible relationship to
      hormonal activity.

PMID- 4357425
TI  - Dietary control of stearyl CoA and alkylacylglycerophosphorylethanolamine
      desaturases in tumor.

PMID- 4357426
TI  - Levels of cyclic AMP in murine L5178Y lymphoblasts grown in different
      concentrations of serum.

PMID- 4357427
TI  - Regulation by beta-adrenergic receptor and muscarinic cholinergic receptor
      activation of intracellular cyclic AMP and cyclic GMP levels in rat lung slices.

PMID- 4357428
TI  - The molecular weight determination of proteins and glycoproteins of RNA enveloped
      viruses by polyacrylamide gel electrophoresis in SDS.

PMID- 4357429
TI  - Cation-dependent light-induced structural changes in visual receptor membranes.

PMID- 4357430
TI  - Biosynthesis and characterization of a phosphatidic acid analog containing beta
      hydroxy fatty acid.

PMID- 4357431
TI  - On the control mechanism of bacterial growth by cyclic adenosine 3',5'
      monophosphate.

PMID- 4357432
TI  - Promotion of conidia aggregation in Aspergillus niger by cyclic AMP and 5'-GMP.

PMID- 4357433
TI  - The in vivo effect of indomethacin and prostaglandin E2 on ACTH and DBCAMP
      induced steroidogenesis in hypophysectomized rats.

PMID- 4357434
TI  - Activity of tubercidin-, toyocomycin-, and sangivamycin-3',5'-cyclic phosphates
      and related compounds with some enzymes of adenosine-3',5'-cyclic phosphate
      metabolism.

PMID- 4357435
TI  - Testosterone binding in the chick oviduct.

PMID- 4357437
TI  - New ATP incorporating activities from rat liver mitochondria: the attachment of a
      portion of ATP to a pronase-sensitive receptor.

PMID- 4357436
TI  - 3-Hydroxybenzoate 6-hydroxylase from Pseudomonas aeruginosa.

PMID- 4357438
TI  - Triacylglycerol secretion in very low density lipoproteins by isolated rat liver
      parenchymal cells.

PMID- 4357439
TI  - Cholesterol in mycoplasma membranes. Composition, ultrastructure and biological
      properties of membranes from Mycoplasma mycoides var. capri cells adapted to grow
      with low cholesterol concentrations.

PMID- 4357440
TI  - Cholesterol in mycoplasma membranes. Correlation of enzymic and transport
      activities with physical state of lipids in membranes of Mycoplasma mycoides var.
      capri adapted to grow with low cholesterol concentrations.

PMID- 4357441
TI  - The adverse effects of drugs on the kidney.

PMID- 4357443
TI  - Psychogeriatrics.

PMID- 4357442
TI  - Alternatives to institutional care.

PMID- 4357444
TI  - Auditory discrimination during REM and non-REM sleep in women before and after
      delivery.

PMID- 4357445
TI  - [Paravaccinia in a dairy herd from Quebec].

PMID- 4357446
TI  - There's more than cancer on the brain. Nuclear medicine and the diagnosis of
      nonneoplastic pediatric brain lesions (or abscess, blood vessel anomaly, or
      clot?).

PMID- 4357447
TI  - [The modern diagnostic methods of liver diseases].

PMID- 4357448
TI  - Effect of prostaglandin E1 on cholesterol biosynthesis in rat liver.

PMID- 4357449
TI  - Prolonged elevation of plasma cortisol levels in dogs treated with an 18 amino
      acid synthetic corticotrophin.

PMID- 4357450
TI  - 5-HT hyperpolarization of bullfrog sympathetic ganglion cell membrane.

PMID- 4357451
TI  - Immunochemical relationships among lysosomal acid phosphohydrolases: DNase II and
      nonspecific phosphodiesterase.

PMID- 4357452
TI  - [The role of cyclic AMP for the function of the peripheral and central nervous
      system (author's transl)].

PMID- 4357454
TI  - Amoebicidal action of bile salts and other surface-active agents on axenically
      grown Entamoeba histolytica.

PMID- 4357453
TI  - Electron-nuclear double resonance study of flavodoxin from Peptostreptococcus
      elsdenii.

PMID- 4357455
TI  - Periphal vascular disease in diabetes mellitus.

PMID- 4357456
TI  - Paralytic poliomyelitis: clinical and virological studies.

PMID- 4357457
TI  - [EPR signals from spin-labeled activated spores of Thermoactinomyces vulgaris
      2681].

PMID- 4357458
TI  - Activation of Na-K activated ATPase in rat brain by catecholamine.

PMID- 4357459
TI  - A scanning electron microscope study of surface features of viral and spontaneous
      transformants of mouse Balb-3T3 cells.
AB  - Cells of the mouse line Balb/3T3 as well as three virus-induced transformants and
      two spontaneous transformants grown in vitro have been studied for their
      topography by scanning electron microscopy. The parent cell in confluent culture
      closely resembles an endothelial cell in its form and in the structure of its
      association with adjacent cells. The tumorigenic transformants produced by SV40,
      murine sarcoma virus, or polyoma viruses are fusiform to pleomorphic and
      distinctly different from the cell of origin. They show relatively smooth
      surfaces except for blebs and marginal microvilli. Perhaps most surprising is the
      similarity they bear to one another. This is made the more singular by the very
      different form shown by the tumorigenic transformants of spontaneous origin. One
      of these, S2-4, possesses a thickened rather than the lamellar form of the parent
      A31 cell and is covered by long microvilli and many spherical blebs. The other,
      TuT(3), more closely resembles the cell of origin but shows extensive ruffling at
      its margins. All transformants grow without evidence of contact inhibition. The
      significance of the surface morphologies and the factors influencing cell form
      are discussed.

PMID- 4357461
TI  - Parenchymal cells from adult rat liver in nonproliferating monolayer culture. II.
      Ultrastructural studies.
AB  - Hepatic parenchymal cells from adult rats, established in vitro as a monolayer,
      have been evaluated by electron microscopy. Within 24 h after the initial
      seeding, the incubated cells were polygonal and in close apposition with three to
      six neighboring cells. The ultrastructure of the monolayer cells was examined at
      this time and after 3 and 10 days of incubation. With the exception of a few
      enlarged mitochondria, organelles in both the 1- and 3-day monolayer cells were
      indistinguishable quantitatively and morphologically from those found in the
      intact liver. After 10 days of incubation, however, the rough-surfaced
      endoplasmic reticulum (RER) had become dilated and vesiculated. In all cells
      studied, portions of RER were found in a close spatial relationship to
      mitochondria. From its frequency, this association appeared to be more than
      fortuitous, and the organelle complex may represent a functional unit necessary
      for new membrane formation, as suggested previously. The Golgi complexes of 1-
      and 3-day cells contained very low density lipoprotein-sized particles, which
      suggests that the monolayer cells synthesize lipoproteins. These electron
      microscope observations demonstrate that adult hepatic parenchymal cells in
      monolayer retain for several days the subcellular structural elements
      characteristic of normally functioning hepatocytes.

PMID- 4357460
TI  - Parenchymal cells from adult rat liver in nonproliferating monolayer culture. I.
      Functional studies.
AB  - Parenchymal cells from adult rat liver have been established in primary monolayer
      culture. Donor animals are subjected to a partial hepatectomy and, 4 days later,
      cells are prepared by collagenase perfusion of the regenerated liver. The hepatic
      parenchymal cells, separated from nonparenchymal material and suspended in serum
      free medium, are placed in plastic tissue culture dishes, where they form a
      monolayer within 24 h. The monolayer cells exhibit minimal mitotic activity and
      demonstrate several major metabolic functions characteristic of liver in vivo;
      these include albumin synthesis and secretion, gluconeogenesis from 3-carbon
      precursors, responsiveness to insulin and glucagon, glycogen synthesis, and
      activity of two microsomal enzymes. These functions are present in the monolayer
      cells for several days at activities similar to those observed in the liver in
      vivo. The findings indicate that hepatic parenchymal cells in this monolayer
      system are viable and behave in many respects like normal adult rat liver.

PMID- 4357464
TI  - Lesions of the breast.

PMID- 4357463
TI  - Cytochemical identification of phosphatase activity in the contractile vacuole of
      Acanthamoeba castellanii.

PMID- 4357462
TI  - Insulin binding to rat liver Golgi fractions.

PMID- 4357465
TI  - Production of cyclic AMP and adenosine by the brain and prothoracic glands of
      Manduca sexta.

PMID- 4357466
TI  - The sulcular epithelium as a reservoir for herpes simplex virus in man.

PMID- 4357467
TI  - [On the etiopathogenesis of 100 cases of neonatal jaundice].

PMID- 4357468
TI  - [Histochemical aspects of the action of phenobarbital on some enzyme systems of
      the rat liver].

PMID- 4357470
TI  - [On psychiatric care (drugs, therapist, community)].

PMID- 4357471
TI  - Effects of adrenaline, noradrenaline and isoprenaline on the electrical and
      mechanical responses of the guinea-pig vas deferens to nerve stimulation.

PMID- 4357469
TI  - [Significance of cyclic 3' 5'-AMP in the pathology of some skin diseases].

PMID- 4357472
TI  - Effects of acetylcholine and some other smooth muscle stimulants on the
      electrical and mechanical responses of the guinea-pig vas deferens to nerve
      stimulation.

PMID- 4357473
TI  - [Serum lipoproteins of vertebrates. Electrophoretic and immunologic study].

PMID- 4357474
TI  - Lipid and fatty acid modifications in plasma lipoproteins of baboons under
      atherogenic diet.

PMID- 4357475
TI  - Marmota monax: a model for studies of cardiovascular, cerebrovascular and
      neoplastic disease.

PMID- 4357476
TI  - The susceptibility and response of wild waterfowl to duck plague virus.

PMID- 4357478
TI  - Auscultation of the abdomen with reference to vascular sounds.

PMID- 4357477
TI  - Studies of human amebiasis. 3. Ameboma: a radiologic manifestation of amebic
      colitis.

PMID- 4357479
TI  - Anaesthesia, surgery and renal function: immediate and delayed effects.

PMID- 4357480
TI  - Substrate specificity of caeruloplasmin indoles and indole isosteres.

PMID- 4357481
TI  - Effect of ethanol administration on cyclic 3',5'-adenosine monophosphate
      metabolism in brain.

PMID- 4357482
TI  - Artifactual subcellular distribution of dopamine beta-hydroxylase. Effects of
      dilution and non-specific protein on the dopamine beta-hydroxylase activity of
      membranes of adrenomedullary and sympathetic nerve vesicles.

PMID- 4357483
TI  - Response of isolated white fat cells to anti-malarial drugs.

PMID- 4357484
TI  - [Influence of antipolyomyelitic vaccination on hyperactive glycoprotein
      biosynthesis in animals infected by Myxovirus].

PMID- 4357485
TI  - Bone sodium exchange. Effect of rachitism and vitamin D3 treatment on chicks.

PMID- 4357486
TI  - A simplified competitive protein-binding assay for adenosine 3',5'-monophosphate
      in plasma.

PMID- 4357487
TI  - Determination of di-(2-ethylhexyl)-phthalate (DEHP) in human plasma.

PMID- 4357488
TI  - Catecholamines and vasomotion.

PMID- 4357489
TI  - Carbon tetrachloride hepatotoxicity: an example of lethal cleavage.

PMID- 4357490
TI  - Peripheral neuropathy caused by chemical agents.

PMID- 4357491
TI  - Vertebrobasilar aneurysms. Experience with 27 cases.

PMID- 4357492
TI  - Limitations of deteriorated tissue for rabies diagnosis.

PMID- 4357493
TI  - Occurrence of canine adenovirus antibodies and non-specific inhibitors of
      haemagglutination in the sera of diverse animal species.

PMID- 4357494
TI  - Effect on calves of the intravenous injection of the enterotoxin of Clostridium
      welchii type A.

PMID- 4357496
TI  - Circadian periodicity of pituitary-adrenal function after p-chlorophenylalanine
      administration in the rat.

PMID- 4357495
TI  - Radioimmunoassay of plasma adrenocorticotrophin in Cushing's syndrome.

PMID- 4357497
TI  - Effect of hypothalamic releasing factors and steroids on release of
      gonadotrophins by organ cultures of human foetal pituitaries.

PMID- 4357498
TI  - Influence of testosterone and cyproterone acetate on the rate of mitosis in
      seminal vesicles of rats.

PMID- 4357500
TI  - Activity of cyclic AMP-dependent microsomal protein kinase and phosphorylation of
      ribosomal protein in rat brain during postnatal development.

PMID- 4357499
TI  - Enzymic activities and sodium, potassium and copper concentrations in mouse brain
      and liver after cuprizone treatment in vivo.

PMID- 4357501
TI  - Effect of hyperphenylalaninemia on fatty acid composition of lipids of rat brain
      myelin.

PMID- 4357502
TI  - Postsynaptic adrenergic-cyclic AMP control of the serotonin content of cultured
      rat pineal glands.

PMID- 4357503
TI  - Acummulation of cyclic adenosine 3', 5'-monophosphate in cerebral cortical slices
      from rat and mouse: stimulatory effect of alpha- and beta-adrenergic agents and
      adenosine.

PMID- 4357504
TI  - Some aspects of visual physiology of the honeybee.

PMID- 4357505
TI  - Small RNAs of Rous sarcoma virus: characterization by two-dimensional
      polyacrylamide gel electrophoresis and fingerprint analysis.
AB  - Approximately 15 to 20 different species of small (4 to 7S) RNAs have been
      purified by two-dimensional polyacrylamide gel electrophoresis of RNA isolated
      from virions of Schmidt-Ruppin D strain of Rous sarcoma virus. Each species of
      small RNA has been isolated free of 70S RNA; nine of them, including 5S and 7S
      RNAs, were also found associated with the 70S genomic RNA. Most of the 4S RNAs
      are present at an average of less than one copy per virion. The 4S RNAs have T1
      RNase (EC 2.7.7.26) fingerprints, which are very similar to those of tRNAs. One
      of the smallest 4S RNAs, which can act as a primer for initiation of RNA-directed
      DNA synthesis, is associated with the 70S RNA in 1 to 2 copies per complex,
      whereas an additional 6 to 8 copies of this molecule are free.

PMID- 4357507
TI  - Analysis of minimal functions of simian virus 40. II. Enhancement of oncogenic
      transformation in vitro by UV irradiation.
AB  - After light UV irradiation (5,000 to 10,000 ergs/mm(2)) "complete" and
      "defective" simian virus 40 (SV40) showed an enhancement of oncogenic
      transformation capacity in Syrian hamster kidney cells in vitro up to 180 and
      270% of the controls, respectively. Simultaneously with the enhancement of
      transformation, an increase in T-antigen induction was observed in CV-1 cells
      infected with light UV-irradiated SV40; infectivity, however, was correspondingly
      reduced by 1 log(10). After strong UV irradiation (10,000 to 80,000 ergs/mm(2))
      of "complete" and "defective" SV40, transformation capacity in vitro proved to be
      the most resistant viral function. It was only slightly reduced in comparison
      with a 4 to 5 log(10) reduction of infectivity. T-antigen induction of SV40 was
      also equally resistant to strong UV irradiation. We found no evidence of
      "multiplicity reactivation" involved in the high resistance of transformation
      capacity of SV40 after UV irradiation. Syrian hamster kidney cells transformed in
      vitro by UV-irradiated SV40 contained the SV40-specific T-antigen and showed the
      same morphology and growth characteristics as cells transformed by non-irradiated
      "complete" or "defective" SV40. They induced malignant tumors after subcutaneous
      inoculation into Syrian hamsters.

PMID- 4357506
TI  - Primary in vivo transcription of vesicular stomatitis virus and temperature
      sensitive mutants of five vesicular stomatitis virus complementation groups.
AB  - The process of adsorption and RNA transcription by vesicular stomatitis virus
      (VSV) in cells has been followed by using highly labeled preparations of VSV
      virions. The initial transcription process (primary parental transcription) is
      rapid and takes about 4 min to develop complete transcripts of the input genome.
      The optimal cell temperature for in vivo transcription is between 36 and 39.5 C,
      although transcription can be detected at 18 C. No negative effect on primary
      parental transcription was obtained by the presence of actinomycin D, puromycin,
      or cycloheximide. Demonstrable primary transcription by selected temperature
      sensitive mutants of all five complementation groups of VSV was obtained at
      either 31 and 34 C (permissive temperatures for virus production) or 39.5 C
      (nonpermissive temperature for virus development). VSV grown in hamster (BHK 21)
      or chicken embryo cells were more efficiently adsorbed and transcribed in BHK
      cells.

PMID- 4357508
TI  - Restricted replication of vesicular stomatitis virus in human lymphoblastoid
      cells.
AB  - Replication of vesicular stomatitis virus (VSV) is restricted in one human
      lymphoblastoid cell line (Raji), but not in another similar cell line (Wil-2),
      compared with growth in HeLa cells. This restriction is characterized by a low
      proportion of cells yielding infectious virus and is associated with limited
      production of 42S virion RNA. Primary transcription of 13S and 26S VSV-specific
      RNA is not restricted in Raji cells, and the 13S RNA produced contains adenylate
      rich sequences. This suggests that the block in Raji cells involves some step
      required for the replication of virion RNA.

PMID- 4357509
TI  - Cleavage of circular, superhelical simian virus 40 DNA to a linear duplex by S1
      nuclease.
AB  - S(1) nuclease, the single-strand specific nuclease from Aspergillus oryzae can
      cleave both strands of circular covalently closed, superhelical simian virus 40
      (SV40) DNA to generate unit length linear duplex molecules with intact single
      strands. But circular, covalently closed, nonsuperhelical DNA, as well as linear
      duplex molecules, are relatively resistant to attack by the enzyme. These
      findings indicate that unpaired or weakly hydrogen-bonded regions, sensitive to
      the single strand-specific nuclease, occur or can be induced in superhelical DNA.
      Nicked, circular SV40 DNA can be cleaved on the opposite strand at or near the
      nick to yield linear molecules. S(1) nuclease may be a useful reagent for
      cleaving DNAs at regions containing single-strand nicks. Unlike the restriction
      endonucleases, S(1) nuclease probably does not cleave SV40 DNA at a specific
      nucleotide sequence. Rather, the sites of cleavage occur within regions that are
      readily denaturable in a topologically constrained superhelical molecule. At
      moderate salt concentrations (75 mM) SV40 DNA is cleaved once, most often within
      either one of the two following regions: the segments defined as 0.15 to 0.25 and
      0.45 to 0.55 SV40 fractional length, clockwise, from the EcoR(I) restriction
      endonuclease cleavage site (defined as the zero position on the SV40 DNA map). In
      higher salt (250 mM) cleavage occurs preferentially within the 0.45 to 0.55
      segment of the map.

PMID- 4357510
TI  - L protein requirement for in vitro RNA synthesis by vesicular stomatitis virus.
AB  - The endogenous transcriptase present in purified vesicular stomatitis (VS)
      virions was solubilized with a Triton X-100 high-salt solution. The polymerase
      activity was purified on glycerol gradients and by phosphocellulose column
      chromatography; the viral proteins present in the active enzyme fractions were
      identified by sodium dodecyl sulfate polyacrylamide gel electrophoresis. It was
      demonstrated that L protein, but not NS protein, was required for in vitro RNA
      synthesis on the VS viral nucleocapsid template. Solubilized L protein rebinds to
      the ribonucleoprotein template when the transcription complex is reconstituted,
      and the RNA synthesized in vitro by purified L protein hybridizes to virion RNA.
      Cyanogen bromide peptide fingerprints indicate that the large L protein is a
      unique polypeptide chain. It is concluded that the L protein functions as the
      transcriptase, and the nucleocapsid NS protein is not essential for in vitro RNA
      synthesis.

PMID- 4357511
TI  - Proteins specified by herpes simplex virus. XI. Identification and relative molar
      rates of synthesis of structural and nonstructural herpes virus polypeptides in
      the infected cell.
AB  - Analyses of polypeptides made in HEp-2 cells infected with herpes simplex virus
      type 1 by high-resolution polyacrylamide gel electrophoresis revealed the
      synthesis of at least 49 infected cell polypeptides (ICP) ranging in molecular
      weight from 15,000 to 280,000. Evidence for virus specificity based on increased
      rates of synthesis postinfection, immunological specificity, and viral control of
      mobility and rate of synthesis was available for 47 of the ICP. These 47
      polypeptides can account for 75% of the virus genetic information assuming a DNA
      molecular weight of 10(8) and asymmetric transcription. On the basis of their
      mobility relative to virion proteins, the ICP were classified as structural (S,
      23 polypeptides), nonstructural (NS, 16 polypeptides), and unassigned (U, 10
      polypeptides). Analysis of the synthesis of the ICP revealed the following. (i)
      Rapid posttranslational cleavages of HSV proteins were not detected; in parallel
      experiments rapid posttranslational cleavages were readily demonstrated in
      poliovirus-infected cells and these were blocked by protease inhibitors. (ii)
      Slow posttranslational changes in the mobility of at least two polypeptides were
      observed. (iii) Analysis of the rates of synthesis of ICP examined at four
      intervals postinfection revealed regulation of the pattern and amount of ICP
      synthesized. ICP formed six classes (A to F) differing in their kinetics of
      synthesis. S and NS ICP were distributed nonrandomly among these classes. Thus,
      of the sum of S protein amino acid sequences apportioned among these kinetic
      classes, 47%, constituting class A and comprising "late" structural proteins,
      were characterized by progressively increasing rates of synthesis until at least
      12 h postinfection; whereas "early" structural proteins constituting class C,
      amounting to 31% of the total amino acid sequences, were synthesized with
      initially increasing rates until 4 h postinfection and with declining rates
      thereafter. NS polypeptides and remaining S polypeptides were distributed among
      the other kinetic classes-B, D, E, and F. Control of protein abundance was
      evident in that the polypeptides were not made in equimolar amounts. However, S
      and NS polypeptides could not be differentiated on the basis of their molar rates
      of synthesis. The bulk of the detected polypeptides did not differ by more than
      eightfold in their molar rates of synthesis.

PMID- 4357512
TI  - RNA synthesis of vesicular stomatitis virus. V. Interactions between
      transcription and replication.
AB  - The temperature-sensitive mutant ts114 of vesicular stomatitis virus is
      temperature-sensitive in both primary and secondary transcription, but not in the
      replication of 40S RNA. The synthesis of 40S RNA is specifically inhibited when
      protein synthesis is shut off. The addition of cycloheximide to cells infected by
      ts114, rapidly inhibits RNA replication at the permissive and nonpermissive
      temperatures. However, the addition of cycloheximide at the nonpermissive
      temperature also results in almost complete recovery of transcription to the
      level found at the permissive temperature. Other inhibitors of protein synthesis
      applied at the nonpermissive temperature result in the same recoverability of the
      apparent temperature-sensitive lesion. Ribonucleic acid products synthesized by
      ts114 at the nonpermissive temperature in the presence of cycloheximide are
      identical to virus-specific messenger RNA by the criteria of size and
      complementarity to virion RNA. When mutant-infected cells are shifted to the
      nonpermissive temperature, incubated for a period of time, and then treated with
      cycloheximide, the ratio of transcriptive to replicative activity varies
      depending on the time at which radioactive precursor is added to cells. This
      suggests an interdependence between replication and transcription during virus
      specific RNA synthesis.

PMID- 4357513
TI  - Nucleic acid synthesis in cytoplasm of Yaba monkey tumor virus-infected cells.
AB  - Yaba tumor virus progeny appeared in cynomolgus monkey kidney cells at 24 h
      postinfection and reached a plateau at 72 h in the first cycle of replication.
      Viral DNA synthesis was first detected at about 3 h and reached a peak in 18 h.
      Maximum coating of viral DNA in infected cells occurred at 4 days postinfection.
      Rapidly labeled RNA was synthesized in the cytoplasm of virus-infected cells. At
      6 h postinfection 7 to 10S RNA was present; this species was present in greater
      amount at 12 h; at 24 h a truncated peak indicated the presence of 14 to 15S as
      well as 7 to 10S RNA. Hybridization data indicated that the largest peak of
      messenger RNA synthesis occurred at 11 to 13 h postinfection and a second,
      slightly smaller, peak occurred at 21 to 23 h.

PMID- 4357514
TI  - Defective interfering particles of poliovirus. IV. Mechanisms of enrichment.
AB  - Infection of HeLa cells by mixtures of standard poliovirus and defective,
      interfering (DI) poliovirus particles leads to a higher ratio of DI particles in
      the progeny than in the inoculum. The extent of this enrichment could be varied
      by various manipulations of the co-infected cells. At any time during the
      infection cycle, virions made within short times after addition of radioactive
      uridine were hyperenriched in DI particles; this transient hyperenrichment fell
      to the equilibrium enrichment level within 45 min after uridine addition. A shift
      of the temperature of infection from 37 to 31 C also led to a hyperenrichment of
      DI particles and pulse-labeling revealed a superimposed transient
      hyperenrichment. By contrast, cells continuously infected at 31 C showed a severe
      decrement in DI particles apparently because poliovirus DI particles behave as
      cold-sensitive mutants for RNA synthesis. Cycloheximide treatment early in the
      infection cycle also led to hyperenrichment. Study of the cycloheximide effect
      showed that the drug acted as if to change the input ratio of standard to DI
      particles. These effects on enrichment can be explained as aspects of two
      different phenomena: enrichment due to preferential DI RNA synthesis and
      enrichment due to preferential encapsidation of DI RNA. Both mechanisms probably
      play a role in the normal level of enrichment.

PMID- 4357515
TI  - Effect of dibutyryl cyclic AMP on the induction of Epstein-Barr virus in hybrid
      cells.
AB  - Treatment of Epstein-Barr virus (EBV) negative somatic cell hybrids with 5'
      iododeoxyuridine (IUdR) induced synthesis of EBV antigens and virus particles.
      When dibutyryl cAMP (Bt(2)-cAMP) was present in medium after exposure of cultures
      to IUdR, the incidence of cells synthesizing EBV early and virus capsid antigens
      was increased. The time necessary for appearance of EBV particles after induction
      by IUdR was significantly reduced in the presence of Bt(2)-cAMP. This enhancement
      was evident to a lesser degree with 3':5' cAMP than with Bt(2)-cAMP and did not
      occur with any other of the related compounds tested. The response observed was
      dose dependent. Untreated (no IUdR) EBV negative hybrid cells exposed to Bt(2)
      cAMP also synthesized EBV antigens. The concentration of intracellular cAMP may
      act as one of the control mechanisms selecting for gene expression in this
      system.

PMID- 4357516
TI  - Trypsin action on the growth of Sendai virus in tissue culture cells. 3.
      Structural difference of Sendai viruses grown in eggs and tissue culture cells.
AB  - Polypeptides of egg-borne Sendai virus (egg Sendai), which is biologically active
      on the basis of criteria of the infectivity for L cells and of hemolytic and cell
      fusion activities, were compared by polyacrylamide gel electrophoresis with those
      of L cell-borne (L Sendai) and HeLa cell-borne Sendai (HeLa Sendai) viruses,
      which are judged biologically inactive by the above criteria. Densitometer
      profiles on the stained gels of egg Sendai resolved six polypeptides (virion
      protein [VP] 1 to VP6), in which VP2 and VP4 were identified as glycoproteins by
      PAS stain. Comparative electropherograms of both L Sendai and HeLa Sendai
      revealed that there were significantly larger amounts in the VP2 region of these
      viruses but VP4 was present only in greatly reduced amounts as compared to egg
      Sendai. It was also found that VP2 of L Sendai and HeLa Sendai consisted of two
      components, VP2a and VP2b, but the one of egg Sendai consisted of only VP2a. A
      mild trypsin treatment which converts both L Sendai and HeLa Sendai to a
      biologically active form selectively removed VP2b from these viruses and
      increased concomitantly the amounts of materials in the VP4 region. The same
      treatment of egg Sendai affected neither its biological activities nor its
      electropherogram. Consequently, gross polypeptide profiles on the stained gels of
      L Sendai and HeLa Sendai after trypsin treatment became favorably comparable to
      that of egg Sendai. Electrophoresis of labeled L Sendai and HeLa Sendai with a
      (3)H-amino acids mixture and (14)C-glucosamine resolved at least three
      glycoproteins, GP1, GP2, and GP3, each corresponding to VP2a, VP2b, and VP4,
      respectively. The trypsin treatment of these viruses removed almost all the
      radioactivity of GP2 and simultaneously increased the radioactive counts of GP3
      and raised small amounts of rapidly moving heterogeneous glycoprotein, GP4. A
      possible relationship between the biological modification and the above
      characteristic polypeptide patterns of Sendai virus was discussed.

PMID- 4357517
TI  - RNA-DNA covalent bonds between the RNA primers and the DNA products formed by RNA
      tumor virus DNA polymerase.
AB  - Initiation of DNA synthesis by endogenous RNA primer molecules was studied with
      three different RNA tumor viruses. The influence of the method of virus
      disruption on the observed RNA-DNA bonds was ascertained. Ether disrupted virions
      of both murine leukemia virus (MuLV) and the B77 strain of avian sarcoma virus
      (B77 virus) have rC-dC and rA-dA covalent linkages between RNA primers and newly
      synthesized DNA. None of the 14 other possible bonds were formed. Ether-disrupted
      virions of avian myeloblastosis virus (AMV) have rU-dC and rA-dA linkages. In
      contrast, work reported herein and from other laboratories shows that Nonidet P
      40 (NP-40)-disrupted virions of all three viruses have only the rA-dA junction.
      Studies with virus particles which were first disrupted with ether and then
      treated with NP-40 indicated that the detergent treatment disallowed the
      formation of the ribopyrimidine-dC internucleotide bond. The same transfers are
      found with AMV in the presence or absence of actinomycin D, where only single
      stranded DNA is formed. This finding is consistent with the notion that virtually
      all of the significant primers have been recognized. In contrast to mature
      virions, transfer experiments with ether-disrupted early harvest (5 min) MuLV
      showed only the rC-dC bond; the rA-dA bond was absent. The short-time harvest
      contains a significantly higher proportion of infectious virions than 24-h
      harvests. Also, since the RNA from early harvest virus is appreciably more
      homogenous than the RNA of mature MuLV, it is concluded that the ribopyrimidine
      dC linkage is the more significant initiation event from a biochemical
      standpoint.

PMID- 4357519
TI  - Effects of simian virus 40-induced transformation on isoaccepting species of
      transfer RNA from mouse fibroblasts.
AB  - Alterations in isoaccepting species of tRNA in mouse fibroblasts transformed by
      simian virus 40 were determined for alanine, arginine, histidine, leucine,
      lysine, phenylalanine, serine, tyrosine, and valine. Significant differences
      between transformed cells in culture and newborn mouse cells are attributed to
      tRNA alterations accompanying differentiation of mouse cells.

PMID- 4357518
TI  - DNA polymerase of murine sarcoma-leukemia virus: lack of detectable RNase H and
      low activity with viral RNA and natural DNA templates.
AB  - Kirsten murine sarcoma-leukemia virus (Ki-MSV[MLV]) was found to contain less
      RNase H per unit of viral DNA polymerase than avian Rous sarcoma virus (RSV).
      Upon purification by chromatography on Sephadex G-200 and subsequent glycerol
      gradient sedimentation the avian DNA polymerase was obtained in association with
      a constant amount of RNase H. By contrast, equally purified DNA polymerase of Ki
      MSV(MLV) and Moloney [Mo-MSV(MLV)] lacked detectable RNase H if assayed with two
      homopolymer and phage fd DNA-RNA hybrids as substrates. On the basis of picomoles
      of nucleotides turned over, the ratio of RNase H to purified avian DNA polymerase
      was 1:20 and that of RNase H to purified murine DNA polymerase ranged between
      <1:2,800 and 5,000. Based on the same activity with poly (A).oligo(dT) the
      activity of the murine DNA polymerase was 6 to 60 times lower than that of the
      avian enzyme with denatured salmon DNA template or with avian or murine viral RNA
      templates assayed under various conditions (native, heat-dissociated, with or
      without oligo(dT) and oligo(dC) and at different template enzyme ratios). The
      template activities of Ki-MSV(MLV) RNA and RSV RNA were enhanced uniformly by
      oligo(dT) but oligo(dC) was much less efficient in enhancing the activity of
      MSV(MLV) RNA than that of RSV RNA. It was concluded that the purified DNA
      polymerase of Ki-MSV(MLV) differs from that of Rous sarcoma virus in its lack of
      detectable RNase H and in its low capacity to transcribe viral RNA and denatured
      salmon DNA. Some aspects of these results are discussed.

PMID- 4357520
TI  - Influence of complement on the neutralization of murine cytomegalovirus by rabbit
      antibody.
AB  - Antiserum against murine cytomegalovirus produced in the rabbit contained
      complement (C')-requiring neutralizing (CRN) antibody. The proportion of CRN was
      extremely high (up to 98%) during the early portion of an immunization procedure,
      whereas the antisera produced late had a much lower proportion that required C'.
      The antiserum produced was specific for MCMV with or without C'.

PMID- 4357521
TI  - Formation of lipid-nucleotide complex by RNA tumor virus preparations.
AB  - RNA tumor virus preparations utilize alpha-(32)P-deoxyribonucleoside
      triphosphates as substrates to form lipid-nucleotide products which are tightly
      associated with protein.

PMID- 4357522
TI  - Low-molecular-weight RNAs of murine sarcoma virus: comparative studies of free
      and 70S RNA-associated components.
AB  - Several low-molecular-weight RNAs were released from mouse leukemia sarcoma virus
      70S RNA under conditions of thermal denaturation. One of them, the 70S-associated
      8S RNA, exhibits a number of structural properties characteristic of a previously
      described free viral 8S RNA. This similarity was revealed by polyacrylamide gel
      electrophoresis and nucleotide composition.

PMID- 4357523
TI  - Location of the T4 gene 32 protein binding site on simian virus 40 DNA.
AB  - The T4 gene 32 protein, which binds to single-stranded but not duplex DNA, forms
      a specifically located denaturation loop in covalently closed circular simian
      virus 40 (SV40) DNA. Cleavage of the SV40 DNA-gene 32 protein complex with a
      restriction endonuclease from Hemophilus parainfluenzae shows the loop center to
      be at 0.46 on the SV40 DNA map. This is within one of the regions of SV40 DNA
      cleaved preferentially by the single-strand-specific nuclease S(1).

PMID- 4357524
TI  - [Differential diagnosis of changes of the optic nerve head (author's transl)].

PMID- 4357525
TI  - [Optic nerve damage through antidiarrhoica containing oxychinoline? (author's
      transl)].

PMID- 4357526
TI  - Rapid screening assay for revertants derived from MSV-transformed cells.

PMID- 4357527
TI  - Subcellular localization of hexokinase in the rat cortex.

PMID- 4357529
TI  - The effect of prostaglandin E1 on norepinephrine-induced membrane depolarization
      and cyclic AMP accumulation in brown fat cells.

PMID- 4357530
TI  - Diurnal variation of plasma angiotensin II in man.

PMID- 4357528
TI  - Structural and functional properties of synapses in insects.

PMID- 4357531
TI  - Plasma lipid and lipoprotein levels in childhood and adolescence.

PMID- 4357532
TI  - [Modification of sleep by hypnotics].

PMID- 4357533
TI  - Estrogen mercapturic acids in the adult male rat.

PMID- 4357534
TI  - Estrogen receptor-anti-estrogen complex: atypical binding by uterine nuclei and
      effects on uterine growth.

PMID- 4357535
TI  - The identification of androstenedione and androstenedione 3-enol glucuronide in
      the blood of a woman with an interstitial cell ovarian tumor after 4-14C
      testosterone.

PMID- 4357536
TI  - [A case of mixed tumor located on the hard palate].

PMID- 4357537
TI  - [Ultrastructure of human peripheral blood lymphocytes with increased adhesive
      capability].

PMID- 4357538
TI  - [Comparative sensitivity of normal and neoplastic cells to the mitostatic action
      of colcemid].

PMID- 4357539
TI  - [Properties of the RH cell line].

PMID- 4357540
TI  - [Effect of vibration with frequencies of 200 Hz on the ultrastructure of nerve
      cells of rat spinal ganglia].

PMID- 4357541
TI  - [Ocular movements during paradoxical sleep and "dysmaturity" (author's transl)].

PMID- 4357542
TI  - Influence of deafferentation of the medial basal hypothalamus on the sensitivity
      of the brain to hyperbaric oxygen.

PMID- 4357543
TI  - Comparison of visual acuity tests and viewing condition interactions.

PMID- 4357544
TI  - [Some indices of kinin system activity in pregnant women and parturients with
      normal labor activity and with primary weak labor].

PMID- 4357545
TI  - Adenoid cystic carcinoma of the male breast: report of a case.

PMID- 4357546
TI  - Renin-secreting Wilms' tumor with severe hypertension. Report of a case and brief
      review of renin-secreting tumors.

PMID- 4357547
TI  - Metronidazole combined with diloxanide furoate in amoebic liver abscess.

PMID- 4357548
TI  - Enzymatic synthesis and crystallographic characterization of an isomorphous
      derivative of yeast formylatable methionine transfer ribonucleic acid containing
      iodocytidine.

PMID- 4357549
TI  - Studies on polynucleotides containing hybrid sequences. Synthesis of
      oligonucleotides containing thymidine, adenosine, and a single
      deoxyribonucleotidyl-(3'-5')-ribonucleotide linkage.

PMID- 4357550
TI  - Inhibition of fumarylacetoacetate fumarylhydrolase by monovalent anions.

PMID- 4357551
TI  - Roles of zinc ion and reduced coenzyme in the formation of a transient chemical
      intermediate during the equine liver alcohol dehydrogenase catalyzed reduction of
      an aromatic aldehyde.

PMID- 4357552
TI  - Observations on the oxidation-reduction properties of bovine erythrocyte
      superoxide dismutase.

PMID- 4357553
TI  - Spin-labeled ribonuclease. A. Selective incorporation of a nitroxide spin label
      sensitive to active-center geometry.

PMID- 4357554
TI  - Conformational studies of angiotensin peptides in aqueous solution by proton
      magnetic resonance.

PMID- 4357555
TI  - Model studies for molybdenum enzymes. Reduction of flavines by mu-oxo
      bis(oxodihydroxo(L-cysteinato)molybdate(V)).

PMID- 4357556
TI  - Polylysine-enhanced effectiveness of plastocyanin in photosystem. I.

PMID- 4357557
TI  - Oxidation-reduction potential dependence of low-temperature photoreactions of
      chloroplast photosystem. II.

PMID- 4357558
TI  - The oxidation mechanisms of thiosulphate and sulphide in Chlorobium
      thiosulphatophilum: roles of cytochrome c-551 and cytochrome c-553.

PMID- 4357559
TI  - Effect of oxidizing treatment on chloroplast photosystem II reactions.

PMID- 4357560
TI  - Isolation of cytoplasmic glucocorticoid-binding protein(s) from rat liver by
      means of affinity chromatography, and its partial characterization.

PMID- 4357562
TI  - Binding of NAD+ to rabbit-muscle glyceraldehydephosphate dehydrogenase. The use
      of N-methylnicotinamidium chloride as a spectral and conformational probe.

PMID- 4357561
TI  - Progesterone-binding protein in human myometrium. Ligand specificity and some
      physicochemical characteristics.

PMID- 4357563
TI  - The effects of trypsin on purified myelin.

PMID- 4357564
TI  - Cell wall glycopeptides of Candida albicans serotypes A and B.

PMID- 4357565
TI  - Structural and functional determinants of Mucor miehei protease. II. Circular
      dichroic studies on the native and periodate-oxidized enzyme.

PMID- 4357566
TI  - Mossbauer spectroscopy of iron in human and rabbit transferrin.

PMID- 4357567
TI  - Simulated behavior states: an approach to specificity in psychobiological
      research.

PMID- 4357568
TI  - Reactivity of vascular smooth muscle in hypertensive rats.

PMID- 4357569
TI  - Myocardial nucleotide synthesis from purine bases and nucleosides. Comparison of
      the rates of formation of purine nucleotides from various precursors and
      identification of the enzymatic routes for nucleotide formation in the isolated
      rat heart.

PMID- 4357571
TI  - Incidence of autoantibodies in cancer patients.

PMID- 4357570
TI  - Selective stimulation of renal nerves in the anesthetized dog. Effect on renin
      release during controlled changes in renal hemodynamics.

PMID- 4357572
TI  - Prediction of the burden of released mental patients.

PMID- 4357573
TI  - Social approaches to community mental health via intake or central reception
      services.

PMID- 4357574
TI  - Proceedings: Some aspects of freezing and drying of microorganisms on the basis
      of cellular water.

PMID- 4357575
TI  - [Renin-secreting tumors].

PMID- 4357576
TI  - [A radiological study of primary pulmonary hypertension following ingestion of
      appetite depressants (author's transl)].

PMID- 4357577
TI  - [Chest survey films for isolated congenital heart defects in infants and children
      (author's transl)].

PMID- 4357578
TI  - [Scanning for functional evaluation of the heart using an E.C.G.-controlled gamma
      camera (author's transl)].

PMID- 4357579
TI  - [Isotopes in the functional diagnosis of the parotid. I. Function of the normal
      parotid (author's transl)].

PMID- 4357580
TI  - [The diagnosis of chronic liver disease using radio-colloid scanning (author's
      transl)].

PMID- 4357581
TI  - [The value of multi-phase isotope techniques for the early diagnosis of organic
      cerebral disease (author's transl)].

PMID- 4357582
TI  - [Bone and joint scans using 99mTc marked pyrophosphate or polyphosphate. A
      preliminary communication (author's transl)].

PMID- 4357584
TI  - [Congenital syphilis (author's transl)].

PMID- 4357583
TI  - [Radiological features of abnormal calcium metabolism in dialysis patients
      (author's transl)].

PMID- 4357585
TI  - [Problems concerning the pathogenesis and genetics of the Klippel-Feil syndrome-
      a comparative study of two cousins (author's transl)].

PMID- 4357586
TI  - [The demonstration of intracranial blood vessels by pneumo-encephalography
      (author's transl)].

PMID- 4357587
TI  - [Regional abnormalities in the cerebral blood flow in Moyamoya disease (author's
      transl)].

PMID- 4357588
TI  - [Functional diagnosis of chronic cervical myelopathies of vertebral origin
      (author's transl)].

PMID- 4357589
TI  - [Simulation of CaWO4-fluorescence radiation for sensitometric exposure of X-ray
      films used with intensifying screens (author's transl)].

PMID- 4357590
TI  - [SI-units in radiology and radiometry].

PMID- 4357591
TI  - [Problems of gastric motility following hyperventilation. Discussion on the paper
      by K. Langemann and K. Hofmann: "Gastric motility in rest and uncer physical
      load" Rofo 115 (1971) 817-821].

PMID- 4357592
TI  - [Pseudo-aneurysm in periostitis ossificans].

PMID- 4357593
TI  - [Aneurysmatic arteriovenous angioma in adolescence].

PMID- 4357594
TI  - [Bilateral angiography of the vena ophthalmica in alcoholic delirium].

PMID- 4357595
TI  - [Accessory vertebral arches between the 4th and 5th lumbar vertebrae (so-called
      asoma)].

PMID- 4357596
TI  - [Long-stem ureteral polyps, prolapsed into the bladder].

PMID- 4357597
TI  - [Calcified renal artery aneurysm in unilateral kidney agenesia and double
      uterus].

PMID- 4357598
TI  - [GERMAN standards. Draft of May 1973].

PMID- 4357599
TI  - Chemical screening and evaluation of coronary and coronary-prone patients.

PMID- 4357600
TI  - A new national strategy to make health services flexible and responsive.

PMID- 4357601
TI  - Attempts to detect homologous autointerference in vivo with influenza virus and
      vesicular stomatitis virus.
AB  - Von Magnus particles of influenza virus and defective interfering T particles of
      vesicular stomatitis virus were unable to provide significant protection of mice
      from disease or death when inoculated intranasally or intracerebrally along with
      moderate or high doses of homologous infectious challenge virus. However, yields
      of infectious virus from the affected organs were reduced as compared to controls
      inoculated with infectious virus alone. Serial intracerebral passage of vesicular
      stomatitis virus in mouse brain at high doses failed to produce T particles
      detectable by in vitro autointerference assays on BHK(21) cells, whether or not T
      particles were introduced along with B virions at the first passage. When very
      low challenge doses of infectious B virions were inoculated intracerebrally along
      with high doses of homologous defective particles, there was significant
      prolongation of life, although most mice died eventually of slowly progressing
      disease. Also, the virus yields in the brains of these mice were significantly
      reduced, and virus was no longer detectable in the brains of "protected" mice
      surviving for 10 days or more. Our results suggest that although homologous
      autointerference does occur in vivo, it is a more complex phenomenon than in
      vitro cell culture experiments might indicate.

PMID- 4357603
TI  - Immunity to chlamydial infections of the eye. V. Passive transfer of antitrachoma
      antibodies to owl monkeys.
AB  - Previous studies have shown that owl monkeys which have had a trachoma agent
      infection were subsequently highly resistant to challenge by both homologous and
      heterologous organisms. In the present study, passive transfer of owl monkey
      serum containing antitrachoma antibody from immune monkeys did not protect
      recipient monkeys from infectious challenge with homologous trachoma. Antibody
      was not detectable in eye secretions of the recipient monkeys until the intensity
      of infection was waning, suggesting but not proving that local antibody synthesis
      rather than simple transudation of serum antibody occurs.

PMID- 4357602
TI  - Differences in clinical and convalescent-phase antibodies of Rhesus monkeys
      infected with monkey pox, tanapox, and Yaba poxviruses.
AB  - Complement-fixing and complement-fixing inhibiting (CFI) antibodies were
      demonstrated in the clinical and convalescent stages, respectively, of rhesus
      monkeys infected with either monkey poxvirus, Tanapoxvirus, or Yaba poxvirus.
      Specificity of the CFI antibody was confirmed by its failure to cross-react with
      heterologous poxvirus antigens and by experiments demonstrating the CFI test as
      being antigen dependent. Serum containing CFI antibody neutralized homologous
      poxvirus but failed to agglutinate antigen-coated, tanned red blood cells. The
      application of CFI test as a seroepidemiologic tool for studies of poxvirus
      infection of man and simian monkeys and the biologic role of CFI antibody in
      pathogenesis were discussed.

PMID- 4357605
TI  - Further studies on the carbohydrate metabolism of immature Schistosoma mansoni.

PMID- 4357604
TI  - Host responses to Epstein-Barr virus and cytomegalovirus infection in leprosy.
AB  - A study was undertaken in patients with leprosy to assess the contribution of
      cell-mediated immunity to the host response to Epstein-Barr virus (EBV) and
      cytomegalovirus (CMV) infection. Sixteen of 72 patients (22%) with lepromatous
      leprosy, with impaired cellular immunity, had anti-EBV titers of 1,640 or higher.
      Only 4 of 49 patients (8%) with tuberculoid leprosy, with intact cell-mediated
      immunity, attained the level of 1:640. The anti-EBV antibody titers were
      significantly higher in patients with lepromatous leprosy (P approximately
      0.025). No significant differences were found in the level of anti-CMV antibody
      titers in patients with the two types of leprosy. The presence of high anti-EBV
      antibody titers in lepromatous leprosy suggests that cell-mediated immunity is a
      significant factor in host response to EBV infection. Host immune responses
      should be taken into consideration when assignment of an etiological role to EBV
      is based upon seroepidemiological data.

PMID- 4357606
TI  - An e.s.r. study of free-radical conversions in irradiated single crystals of N
      acetylglycine in the temperature range 77-300 K.

PMID- 4357607
TI  - An enzyme histochemical study of mesothelial cells in rodents.

PMID- 4357608
TI  - Effects of acetazolamide on the urinary excretion of cyclic AMP and on the
      activity of renal adenyl cyclase.
AB  - Acetazolamide, an inhibitor of the enzyme carbonic anhydrase, increased the
      urinary excretion of cyclic AMP in normal and parathyroidectomized rats. The
      increase was greater in rats with intact parathyroid glands than in
      parathyroidectomized rats. This rise in the urinary excretion of cyclic AMP was
      not due to an increase in urine flow or a change in urine pH. Furosemide caused
      an increase in urine flow, but did not affect the excretion of cyclic AMP or
      phosphate. Alkalinization of the urine with bicarbonate did not increase the
      urinary excretion of phosphate or cyclic AMP. Acetazolamide increased the
      productionof cyclic AMP by rat renal cortical slices in vitro. This effect was
      dose-dependent. Acetazolamide also stimulated the activity of renal cortical
      adenyl cyclase in a dose-dependent manner but had no effect on the activity of
      cyclic nucleotide phosphodiesterase. The pattern of urinary excretion of cyclic
      AMP and phosphate after administration of acetazolamide was similar to that
      observed in rats given parathyroid hormone. It is suggested that acetazolamide
      stimulates the renal production of cyclic AMP by activating adenyl cyclase and
      that this may be the mechanism by which this inhibitor of carbonic anhydrase
      produces phosphaturia.

PMID- 4357609
TI  - Hemolytic plaque formation by leukocytes in vitro. Control by vasoactive
      hormones.
AB  - Histamine, beta-adrenergic amines, and prostaglandins inhibited hemolytic plaque
      formation by splenic leukocytes from immunized mice. The same agents had
      previously been shown to prevent both the IgE-mediated release of histamine from
      human basophils and the immunologically specific cytolytic activity of murine
      lymphocytes, through stimulation of the production of cyclic AMP in leukocytes.
      We therefore tested the hypothesis that cyclic AMP might mediate an inhibitory
      effect of these drugs by comparing the ability of these agents to inhibit plaque
      formation with their effects on cyclic AMP accumulation in leukocytes. In splenic
      cells from three mouse strains, the dose-dependent effects of these agents of
      cyclic AMP correlated with their inhibition of plaque formation. Beta- but not
      alpha-adrenergic agonists were effective in both systems, and the effects of
      isoproterenol were inhibited by propranolol. Histamine was approximately
      equipotent with isoproterenol in both systems. Two prostaglandins (E(1) and E(2))
      were effective in both systems, but prostaglandin F(2alpha) was not. Dibutyryl
      cyclic AMP, a lipid-soluble analog of the endogenous nucleotide, inhibited plaque
      formation by cells of all three strains. Theophylline, an inhibitor of cyclic AMP
      degradation, inhibited plaque formation slightly, but potentiated the effects of
      histamine, isoproterenol, and the prostaglandins on both cyclic AMP accumulation
      and plaque formation. Finally, cholera enterotoxin, a potent activator of adenyl
      cyclase, produced a delayed inhibition of plaque formation and a parallel
      increase in leukocyte cyclic AMP content; both effects of the toxin were blocked
      by canine antitoxin. These results suggest that leukocyte cyclic AMP may act as a
      "second messenger" to suppress plaque formation in vitro. The inhibitory effects
      of hormones and cyclic AMP on plaque formation are strikingly similar to their
      effects on in vitro models of immediate and cell-mediated hypersensitivity. The
      physiologic significance of these findings is not yet known.

PMID- 4357610
TI  - Plasma clearance rates and renal clearance of 3H-labeled cyclic AMP and 3H
      labeled cyclic GMP in the dog.
AB  - Previously, in an attempt to understand the mechanisms involved in the regulation
      of plasma cyclic nucleotides, we measured concentrations of adenosine 3',5'
      monophosphate (cAMP) and guanosine 3',5'-monophosphate (cGMP) in plasma from
      selected blood vessels of anesthetized dogs. The observation that the renal
      venous plasma concentrations of both cyclic nucleotides were less than arterial
      concentrations suggested that the kidney might be an important site for the
      elimination of these compounds from plasma and prompted further investigation of
      the renal handling of these compounds. Tracer doses of either [(3)H]cAMP or
      [(3)H]cGMP were administered to anesthetized dogs by constant intravenous
      infusion, and metabolic clearance rates were determined. Concentrations of
      endogenous cyclic nucleotide and of cyclic nucleotide radioactivity were measured
      in aortic and renal venous plasma as well as in urine. Renal venous plasma
      [(3)H]cGMP was 39% and [(3)H]cAMP was 65% of the concentration in arterial
      plasma. Endogenous cyclic nucleotide levels showed a similar relationship. The
      plasma clearance rates (PCR) were 271+/-27 ml/min (mean+/-SE) for cGMP and 261+/
      17 for cAMP. The total kidney clearance (calculated as the renal plasma flow x
      renal cyclic nucleotide extraction ratio) accounted for 52+/-4% and 30+/-2% of
      the PCR for cGMP and cAMP, respectively. Only about two-thirds of the total
      kidney clearance of each cyclic nucleotide could be accounted for by urinary
      excretion, the remainder presumably being the result of renal metabolism. The
      urinary clearances of (3)H-labeled cGMP (40.9+/-4.2 ml/min) and endogenous cGMP
      (45.0+/-2.3 ml/min) were not significantly different from each other. Both were
      approximately 50% greater than the glomerular filtration rate, which was 27.1+/
      2.0 ml/min, indicating that a significant amount of urinary cGMP is derived from
      plasma by tubular secretion. In contrast, the urinary clearances of (3)H-labeled
      cAMP (23.7+/-1.9 ml/min) and endogenous cAMP (27.2+/-2.6 ml/min) were nearly
      equal both to each other and to the glomerular filtration rate, which was 24.6+/
      1.7 ml/min. Thus, in the dog, glomerular filtration of plasma cAMP appears to be
      responsible for most of the cAMP found in urine. Renla production of cAMP, which
      in humans contributes from a third to a half of the urinary cAMP, was
      quantitatively of minor importance in the dog.Thus, under the conditions of these
      experiments in dogs, renal elimination appears to be responsible for half of the
      PCR of cGMP and about a third of the PCR of cAMP. About a third of the renal
      elimination of both cyclic nucleotides appears to be due to metabolic degradation
      within the kidney, and the balance is due to excretion in the urine.

PMID- 4357611
TI  - Sources of cyclic nucleotides in plasma.
AB  - In order to determine the sites of net production and removal of the cyclic
      nucleotides in plasma, various blood vessels were catheterized in 17 anesthetized
      dogs and arterial and venous concentrations of adenosine 3',5'-monophosphate
      (cAMP) and guanosine 3',5'-monophosphate (cGMP) were measured by
      radioimmunoassay. Aortic cAMP was 30+/-2 nM (mean+/-SE) and cGMP was 13+/-1 nM.
      There were no significant differences for either cyclic nucleotide between the
      concentration in the aorta and that in the inferior vena cava, coronary sinus,
      hepatic vein, and femoral vein. The concentration of cAMP in renal venous plasma
      was 25% lower than in aortic plasma, and renal venous cGMP was 51% lower than in
      the aorta. The pulmonary arterial concentrations of cAMP and cGMP were slightly
      lower than in the aorta. The concentration of cGMP in the superior mesenteric
      vein plasma was 83% greater than in aortic plasma; the concentration of cAMP in
      this vessel was only 16% greater than that in the aorta. Superior vena cava
      concentrations of both cyclic nucleotides were slightly greater than arterial
      concentrations. THE RESULTS SUGGEST THAT: (a) the kidneys are a major site of
      removal of both cyclic nucleotides from plasma. (b) The lungs may be a site of
      net addition of both cyclic nucleotides to plasma. (c) The small intestine is a
      site of net production of both cyclic nucleotides, particularly cGMP. (d) The
      liver probably removes cyclic nucleotides from plasma. (e) Since no other organs
      or regions studied added detectable net amounts of cyclic nucleotides to plasma,
      and since the turnover of these compounds in plasma is known to be rapid, the
      production of plasma cyclic nucleotides under basal conditions may well be the
      result of small net contributions may well be the result of small net
      contributions from many tissues or bidirectional fluxes between tissues and
      plasma, or both.

PMID- 4357612
TI  - Effect of glucagon on net splanchnic cyclic AMP production in normal and diabetic
      men.
AB  - Glucagon activates hepatic adenylate cyclase, thereby increasing acutely the
      liver content of cyclic AMP (cAMP) as well as the release of cAMP into the
      hepatic vein. Insulin, on the other hand, antagonizes this glucagon-mediated cAMP
      production, thus providing a hypothetical mechanism through which insulin might
      correct some of the metabolic abnormalities of diabetes. To study this hormonal
      interaction in man, net splanchnic cAMP production (NScAMPP) was investigated in
      normal and insulin-dependent diabetic men under basal conditions and in response
      to intravenous glucagon, 50 ng/kg/min for 2 h. In normals (n=19), basal hepatic
      vein cAMP concentration was 23.6+/-1.1 nM and NScAMPP was 1.7+/-0.6 nmol/min.
      Glucagon stimulated NScAMPP in four normal subjects to a peak of 99.6+/-43
      nmol/min at 25 min with a subsequent fall to 12.4+/-5.1 nmol/min by 90 min
      despite continuing glucagon infusion. Endogenous insulin secretion was stimulated
      as indicated by rising levels of immunoreactive insulin and C-peptide (connecting
      peptide) immunoreactivity, raising the possibility that endogenous insulin might
      be responsible for the fall in NScAMPP that followed the initial spike. In the
      diabetics (n=8), basal hepatic vein cAMP concentration was 24.7+/-1.2 nM and
      NScAMPP was undetectable. Glucagon stimulated NScAMPP in five diabetics to a peak
      of 169.9+/-42.6 with a subsequent fall to 17.4+/-3.9 nmol/min by 90 min even
      though endogenous insulin secretion was not stimulated (no rise in C-peptide
      immunoreactivity). Although the mean increase in NScAMPP was greater in the
      diabetics, the two groups did not differ significantly.Conclusions. In normal
      resting man the liver is a significant source of circulating cAMP. Diabetics do
      not release abnormally large amounts of hepatic cAMP under basal conditions.
      Glucagon markedly enhances hepatic cAMP release with a spike-decline pattern in
      both normal and diabetic men. The decline in hepatic cAMP release despite
      continuing glucagon stimulation is due to factors other than a stimulation of
      insulin secretion.

PMID- 4357613
TI  - Induction of the platelet release reaction by phytohemagglutinin.
AB  - We have previously shown that the erythroagglutinating phytohemagglutinin (E-PHA)
      from Phaseolus vulgaris binds to the surface of intact human platelets and that
      adenylate cyclase activity in the particulate fraction of E-PHA-treated platelets
      is lower than in comparable controls. We now find that E-PHA induces release of
      [(14)C]serotonin from platelets. Release follows binding of E-PHA, and a haptenic
      inhibitor of E-PHA binding prevents induction of release. E-PHA does not produce
      platelet lysis and has little effect on [(14)C]serotonin uptake. Platelets
      possess approximately 300,000 receptor sites of E-PHA per cell, and we estimate
      that about 15% of these sites must be occupied by E-PHA to initiate the release
      reaction. Prior incubation of platelets with prostaglandin E(1), theophylline, or
      dibutyryl cyclic AMP prevents E-PHA-induced release, although these agents have
      little effect on E-PHA binding to platelets. Thrombin and E-PHA produce different
      rates and extents of serotonin release. Thrombin (1 U/ml) causes release of 75
      85% of platelet [(14)C]-serotonin, with half-maximal release occurring less than
      0.5 min after thrombin addition. E-PHA, however, induces release of only 30-60%
      of platelet serotonin at a 10-fold slower rate. In addition, utilizing electron
      microscopy, we have observed striking differences in the morphological changes
      that occur in platelets exposed to E-PHA as compared with thrombin. Thus, the
      platelet release reaction may be triggered in part by binding of E-PHA to the
      cell surface, but this reaction only partially resembles that produced by
      thrombin.

PMID- 4357614
TI  - Separation of specific antibody-forming mouse cells by their adherence to
      insolubilized endogenous hormones.
AB  - Spleen cells from mice immunized with sheep red cells were separated by
      differential adherence to insolubilized histamine, catecholamines, and
      prostaglandins. The hormones were insolubilized by linking them to Sepharose
      beads through a protein carrier. We measured hemolytic plaque formation (per
      million splenic leukocytes) of cells which passed through columns of hormone
      carrier-Sepharose beads (i.e., those cells that failed to bind). As compared with
      control (no column) cells, the number of plaque-forming cells was substantially
      reduced by passage through histamine, epinephrine, isoproterenol, and
      prostaglandin-E(2) columns. Plaque-forming cells were not significantly reduced
      by passage through carrier Sepharose (another control) or norepinephrine- and
      prostaglandin-F(2alpha)-carrier Sepharose columns. Thus, the ability of an
      insolubilized hormone preparation to subtract plaque-forming cells roughly
      correlated with the presence of pharmacologic receptors for the corresponding
      free hormones, as judged by stimulation of cyclic AMP accumulation in the same
      cells, reported previously. Both 19S and 7S plaque-forming cells were subtracted
      by columns prepared from pharmacologically active hormones, but none of the
      insolubilized hormones stimulated accumulation of intracellular cyclic AMP. The
      cell membrane phenomenon that allows adherence to a given hormone-carrier-bead
      column may be identical with the cell receptor.

PMID- 4357615
TI  - Mechanisms of lysosomal enzyme release from human leukocytes. II. Effects of cAMP
      and cGMP, autonomic agonists, and agents which affect microtubule function.
AB  - Selective release of inflammatory materials from leukocyte lysosomes is reduced
      by compounds which increase cyclic 3',5'-adenosine monophosphate (cAMP) levels in
      suspensions of human leukocytes and is augmented by agents which increase cyclic
      3',5'-guanosine monophosphate (cGMP) levels in these cell suspensions. Lysosomal
      enzymes are released in the absence of phagocytosis when cytochalasin B (5
      mug/ml) converts polymorphonuclear leukocytes (PMN) to secretory cells: lysosomes
      merge directly with the plasma membrane upon encounter of PMN with zymosan, and
      cells selectively extrude substantial proportions of lysosomal, but not
      cytoplasmic enzymes. beta-Adrenergic stimulation of human leukocytes produced a
      dose-related reduction in beta-glucuronidase release (blocked by 10(-6) M
      propranolol) whereas alpha-adrenergic stimulation (phenylephrine plus
      propranolol) was ineffective. In contrast, the cholinergic agonist
      carbamylcholine chloride enhanced enzyme secretion, an effect blocked by 10(-6) M
      atropine. Incubation of cells with exogenous cAMP or with agents that increase
      endogenous cAMP levels (prostaglandin E1, histamine, isoproterenol, and cholera
      enterotoxin) reduced extrusion of lysosomal enzymes; in contrast, exogenous cGMP
      and carbamylcholine chloride (which increases endogenous cGMP levels), increased
      beta-glucuronidase release. Whereas colchicine (5 x 10(-4) M), a drug which
      impairs microtubule integrity, reduced selective enzyme release, deuterium oxide,
      which favors microtubule assembly, enhanced selective release of lyosomal
      enzymes. The data suggest that granule movement and acid hydrolase release from
      leukocyte lysosomes requires intact microtubules and may be modulated by
      adrenergic and cholinergic agents which appear to provoke changes in
      concentrations of cyclic nucleotides.

PMID- 4357616
TI  - The rapid changes of hepatic glycolytic enzymes and fructose-1,6-diphosphatase
      activities after intravenous glucagon in humans.
AB  - Glucagon (0.04-0.09 mg/kg/min) was given intravenously for either 2 or 3 min to
      eight patients with fasting-induced hypoglycemia. One child had hepatic
      phosphorylase deficiency, two children had glucose-6-phosphatase deficiency, two
      children had debrancher enzyme (amylo-1,6-glucosidase) deficiency, and two
      children and one adult had decreased hepatic fructose-1,6-diphosphatase (FDPase)
      activity. Liver biopsy specimens were obtained before and immediately after the
      glucagon infusion. The glucagon caused a significant increase in the activity of
      FDPase (from 50+/-10.0 to 72+/-11.7 nmol/mg protein/min) and a significant
      decrease in the activities of phosphofructokinase (PFK) (from 92+/-6.1 to 41+/
      8.1 nmol/mg protein/min) and pyruvate kinase (PK) (from 309+/-39.4 to 165+/-23.9
      nmol/mg protein/min). The glucagon infusion also caused a significant increase in
      hepatic cyclic AMP concentrations (from 41+/-2.6 to 233+/-35.6 pmol/mg protein).
      Two patients with debrancher enzyme deficiency who had biopsy specimens taken 5
      min after the glucagon infusion had persistence of enzyme and cyclic AMP changes
      for at least 5 min. One child with glucose-6-phosphatase deficiency was given
      intravenous glucose (150 mg/kg/min) for a period of 5 min after the glucagon
      infusion and biopsy. The plasma insulin concentration increased from 8 to 152
      muU/ml and blood glucose increased from 72 to 204 mg/100 ml. A third liver biopsy
      specimen was obtained immediately after the glucose infusion and showed that the
      glucagon-induced effects on PFK and FDPase were completely reversed. The glucagon
      infusion caused an increase in hepatic cyclic AMP concentration from 38 to 431
      pmol/mg protein but the glucose infusion caused only a slight decrease in hepatic
      cyclic AMP concentration (from 431 to 384 pmol/mg protein), which did not appear
      to be sufficient to account for the changes in enzyme activities. Hepatic glucose
      6-phosphatase and fructose-1,6-diphosphate aldolase activities were not altered
      by either the glucagon or the glucose infusion in any patients. Cyclic AMP (0.05
      mmol/kg) was injected into the portal vein of adult rats and caused enzyme
      changes similar to those seen with glucagon administration in humans. Our
      findings suggest that rapid changes in the activities of PFK, PK, and FDPase are
      important in the regulation of hepatic glycolysis and gluconeogenesis,
      respectively, in humans and that cyclic AMP may mediate the glucagon- but
      probably not the glucose-insulin-induced changes in enzyme activities.

PMID- 4357617
TI  - Effects of weight reduction on obesity. Studies of lipid and carbohydrate
      metabolism in normal and hyperlipoproteinemic subjects.
AB  - Considerable controversy exists over the purported role of obesity in causing
      hyperglycemia, hyperlipemia, hyperinsulinemia, and insulin resistance; and the
      potential beneficial effects of weight reduction remain incompletely defined.
      Hypertriglyceridemia is one of the metabolic abnormalities proposed to accompany
      obesity, and in order to help explain the mechanisms leading to this abnormality
      we have proposed the following sequential hypothesis: insulin resistance -->
      hyperinsulinemia --> accelerated hepatic triglyceride(TG) production --> elevated
      plasma TG concentrations. To test this hypothesis and to gain insight into both
      the possible role of obesity in causing the above metabolic abnormalities and the
      potential benefit of weight reduction we studied the effects of weight loss on
      various aspects of carbohydrate and lipid metabolism in a group of 36 normal and
      hyperlipoproteinemic subjects. Only weak to absent correlations (r = 0.03 - 0.46)
      were noted between obesity and the metabolic variables measured. This points out
      that in our study group obesity cannot be the sole, or even the major, cause of
      these abnormalities in the first place. Further, we have observed marked
      decreases after weight reduction in fasting plasma TG (mean value: pre-weight
      reduction, 319 mg/100 ml; post-weight reduction, 180 mg/100 ml) and cholesterol
      (mean values: pre-weight reduction, 282 mg/100 ml; post-weight reduction, 223
      mg/100 ml) levels, with a direct relationship between the magnitude of the fall
      in plasma lipid values and the height of the initial plasma TG level. We have
      also noted significant decreases after weight reduction in the insulin and
      glucose responses during the oral glucose tolerance test (37% decrease and 12%
      decrease, respectively). Insulin and glucose responses to liquid food before and
      after weight reduction were also measured and the overall post-weight reduction
      decrease in insulin response was 48% while the glucose response was relatively
      unchanged. In a subgroup of patients we studied both the degree of cellular
      insulin resistance and the rate of hepatic very low density (VLDL) TG production
      before and after weight reduction. These subjects demonstrated significant
      decreases after weight reduction in both degree of insulin resistance (33%
      decrease) and VLDL-TG production rates (40% decrease). Thus, weight reduction has
      lowered each of the antecedent variables (insulin resistance, hyperinsulinemia,
      and VLDL-TG production) that according to the above hypothesis lead to
      hypertriglyceridemia, and we believe the overall scheme is greatly strengthened.
      Furthermore, the consistent decreases in plasma TG and cholesterol levels seen in
      all subjects lead us to conclude that weight reduction is an important
      therapeutic modality for patients with endogenous hypertriglyceridemia.

PMID- 4357618
TI  - Cholinergic and beta-adrenergic compounds in the control of drinking behavior in
      the rat.

PMID- 4357619
TI  - Calciferol metabolism and intestinal calcium transport in the chick with reduced
      renal function.

PMID- 4357620
TI  - Connective tissue activation. VI. The effects of cylic nucleotides on human
      synovial cells in vitro.

PMID- 4357621
TI  - Effect of estrogens and a progestogen on platelet adhesiveness and aggregation in
      rabbits.

PMID- 4357622
TI  - Phosphorylative capacity of liver mitochondria with an elevated ratio of
      cytochrome c+c1 to cytochrome a(+a3).

PMID- 4357623
TI  - Sarcoplasmic reticulum in the portal vein heart and ventricle of the cyclostome
      Myxine glutinosa (L.).

PMID- 4357624
TI  - Phosphorylation of cardiac native tropomyosin and troponin: inhibitory effect of
      actomyosin and possible presence of endogenous myofibrillar-located cyclic-AMP
      dependent protein kinase.

PMID- 4357625
TI  - Parotid tumors and the orbital apex syndrome.

PMID- 4357626
TI  - Enhanced detection of a skeletal lesion with delayed 99mTc-polyphosphate bone
      scanning.

PMID- 4357627
TI  - Effect of various steroids and ACTH on distribution of zoxazolamine in rats.

PMID- 4357628
TI  - [Renal component of the antigravity function of the organism].

PMID- 4357630
TI  - Optical recording of impulses in individual neurones of an invertebrate central
      nervous system.

PMID- 4357629
TI  - mRNA transcription linked to the morphological and plasma membrane changes
      induced by cyclic AMP in tumour cells.

PMID- 4357631
TI  - [Thyroid pathology of hypothalamic origin].

PMID- 4357632
TI  - In vitro effects of lipids on fibrinolysis.

PMID- 4357634
TI  - [Characteristics of the combined course of dysentery and viral respiratory
      infections in children].

PMID- 4357633
TI  - Lipid infusions in man. Ultrastructural studies on blood platelet uptake of fat
      particles.

PMID- 4357635
TI  - [Spin-lattice relaxation in concentrated solutions of herring-sperm DNA and the
      problem of water bound to DNA (author's transl)].

PMID- 4357636
TI  - [The epidermis of the pupae of Tenebrio molitor L. as target organ for the
      juvenile hormone analogue 10,11-epoxy-6,7-trans-2,3-trans-farnesylpropenylether
      (author's transl)].

PMID- 4357637
TI  - [Stimulation of embryonic rat cells by calf serum. V. Metabolism of inositol- and
      choline phospholipids (author's transl)].

PMID- 4357638
TI  - [Pregnancies following methotrexate treatmnet. Chromosome analysis in mother and
      child].

PMID- 4357640
TI  - [Deslysylviomycin. I. Its isolation and physico-chemical properties].

PMID- 4357639
TI  - The effect of clonazepam (Ro 5-4023) in the syndrome of infantile spasms with
      hypsarrhythmia and in petit mal variant of Lennox syndrome. Preliminary report.

PMID- 4357641
TI  - [Semi-synthetic penicillins. XI. Antimicrobial in vitro action of 6
      formamidinopenicillanic acids, derivatives of some secondary cyclic amines].

PMID- 4357642
TI  - [Semi-synthetic penicillins. XII. Bacteriostatic and bactericidal in vitro action
      of 6-(N-1', 6'-hexylenoformamidino)-penicillanic acid on Gram negative bacteria].

PMID- 4357643
TI  - Adenyl cyclase.

PMID- 4357644
TI  - The chemistry and biological properties of nucleotides related to nucleoside
      3',5'-cyclic phosphates.

PMID- 4357645
TI  - Clinical studies and applications of cyclic nucleotides.

PMID- 4357646
TI  - Protein kinases and protein kinase substrates.

PMID- 4357647
TI  - Analysis of the photochemical isomers of ergosterol by column chromatography.

PMID- 4357648
TI  - Determination of nicotinamide in some injections of B-complex vitamins by thin
      layer chromatography.

PMID- 4357649
TI  - Male infertility caused by abnormal androgen production in the adrenal cortex.

PMID- 4357651
TI  - Identification of the toxic principle in a sample of poaefusarin.
AB  - A sample of poaefusarin (a mycotoxin suspected of being one of the toxins
      involved in alimentary toxic aleukia in the U.S.S.R.) was received from a Soviet
      scientist for evaluation and comparison with other mycotoxins. Although
      poaefusarin is presumed to be a steroid, analyses by thin-layer chromatography,
      gas-liquid chromatography, and infrared, ultraviolet, and mass spectrometry could
      not confirm the presence of a steroid structure. However, 2.5% of the sample was
      made up of the trichothecene T-2 toxin, an amount sufficient to explain the
      toxicity found in the rat and rabbit skin toxicity tests. In addition,
      neosolaniol (0.14%), T-2 tetraol (0.6%), and zearalenone (F-2) (0.43%) were
      present in the sample. Since the toxicity was found to be associated only with T
      2 toxin, no attempt was made to determine the nature of the other nontoxic
      components of the sample.

PMID- 4357650
TI  - Growth of Clostridium perfringens in food proteins previously exposed to
      proteolytic bacilli.
AB  - Proteolytic sporeforming bacteria capable of surviving processing heat treatments
      in synthetic or fabricated protein foods exhibited no antagonistic effects on
      growth of Clostridium perfringens, but instead shortened the lag of subsequent
      growth of C. perfringens in sodium caseinate and isolated soy protein. Bacillus
      subtilis A cells were cultured in 3% sodium caseinate or isolated soy protein
      solutions. The subsequent effect on the lag time and growth of C. perfringens
      type A (strain S40) at 45 C was measured by colony count or absorbance at 650 nm,
      or both. B. subtilis incubation for 12 h or more in sodium caseinate reduced the
      C. perfringens lag by 3 h. Incubation of 8 h or more in isolated soy protein
      reduced the lag time by 1.5 h. Molecular sieving of the B. subtilis-treated
      sodium caseinate revealed that all molecular sizes yielded a similar reduced lag
      time. Diethylaminoethyl-Sephadex ion exchange fractionation and subsequent amino
      acid analysis indicated that the lag time reduction caused by B. subtilis
      incubation was not related to charge of the peptides nor to their amino acid
      composition. Apparently the shortened C. perfringens lag in these B. subtilis
      hydrolyzed food proteins was a result of the protein being more readily available
      for utilization by C. perfringens.

PMID- 4357652
TI  - Inactivation of foot-and-mouth disease virus with ethylenimine.
AB  - Foot-and-mouth disease virus (FMDV) was inactivated by ethylenimine (EI) at three
      concentrations and two temperatures. Comparison of inactivation kinetics and the
      antigenic and immunogenic potency of EI and N-acetylethylenimine (AEI)
      inactivated FMDV indicates that EI has nearly optimal characteristics as an
      inactivant for FMDV vaccine preparation. Although AEI-inactivated FMDV has proved
      to be a potent specific immunogen, an equivalent percentage of EI inactivated
      FMDV at substantially faster rates and produced an equally potent immunogen. In
      addition, EI inactivated FMDV at rates that were essentially linear throughout
      the loss of nearly all measurable infectivity.

PMID- 4357654
TI  - Proton magnetic double-resonance study of angiotensin II (Asn1Val5) in aqueous
      solution employing correlation spectroscopy. Assignment of peptide NH resonances
      and transfer of saturation from water.

PMID- 4357653
TI  - Simplified method for purification of Clostridium perfringens type A enterotoxin.
AB  - Purification of Clostridium perfringens type A enterotoxin from sporulated cells
      was simplified. The method consisted of precipitation of the enterotoxin from the
      extract of sonically treated cells at 40% saturation of ammonium sulfate at pH 7,
      differential solubilization in 0.02 M phosphate buffer, pH 6.7, and repeated gel
      filtration on Sephadex G-200. The purified enterotoxin was at least 98% pure in
      ultracentrifugation, polyacrylamide gel electrophoresis, and agar gel double
      diffusion. Recovery was over 74% from the sporulated cell extract. The toxin had
      biological activities of at least 4,700 mouse intravenous minimal lethal doses/mg
      of N, 3,900 capillary permeability-increasing U/mg of N in the guinea pig skin,
      and 210 rabbit intestinal loop distension U/mg of N. The toxin, containing no
      hexose, lipid, or nucleic acid, appeared to be identical in sedimentation
      constant, isoelectric point, and ultraviolet absorption spectrum to the toxin
      purified previously by different procedures.

PMID- 4357655
TI  - Kinetic studies of fluoride binding by cytochrome c peroxidase.

PMID- 4357656
TI  - Kinetic and equilibrium studies of cyanide binding by cytochrome c peroxidase.

PMID- 4357658
TI  - Functional groups of diphosphopyridine nucleotide linked isocitrate dehydrogenase
      from bovine heart. II. Studies of an active amino group by reaction with
      aldehydes.

PMID- 4357657
TI  - Functional groups of diphosphopyridine nucleotide linked isocitrate dehydrogenase
      from bovine heart. I. Studies of an active amino group by amidination, arylation,
      acetylation, and carbamylation.

PMID- 4357659
TI  - Electronic substituent effects during the liver alcohol dehydrogenase catalyzed
      reduction of aromatic aldehydes.

PMID- 4357660
TI  - An unproductive binary complex of liver alcohol dehydrogenase and a chromophoric
      aldehyde.

PMID- 4357662
TI  - Regulation of pea leaf ribulose-5-phosphate kinase activity.

PMID- 4357661
TI  - Modulation of succinate dehydrogenase in response to environmental stress
      conditions of hypobaria and hypoxia.

PMID- 4357663
TI  - Phosphorylation of muscle proteins by cyclic adenosine 3',5'-monophosphate
      dependent protein kinase from muscle.

PMID- 4357664
TI  - Adenylate kinase from Thiobacillus neapolitanus. Unique properties, possibly
      designed to serve a unique metabolic function.

PMID- 4357665
TI  - A surface p-nitrophenyl phosphatase of frog gastric mucosa.

PMID- 4357667
TI  - Purification of phospholipase C (alpha-toxin) from Clostridium perfringens.

PMID- 4357668
TI  - Distribution of lysosomal enzymes between parenchymal and Kupffer cells of rat
      liver.

PMID- 4357666
TI  - Further characterization of a specific p-nitrophenylphosphatase from baker's
      yeast.

PMID- 4357669
TI  - The integrity of human lymphoblastoid RNA after incorporation by human skin
      fibroblasts.

PMID- 4357671
TI  - Hydroxylamine-O-sulfonic acid: in vitro and possible in vivo reaction with DNA.

PMID- 4357670
TI  - Study of methyl-CCNU(NSC-95441) in the treatment of lung cancer.

PMID- 4357672
TI  - Changes in microsomal enzyme activities during DAB carcinogenesis.

PMID- 4357673
TI  - Platelet function studies in coronary artery disease.

PMID- 4357674
TI  - Hyper-low density lipoproteinemia in United States Air Force recruits.

PMID- 4357675
TI  - [Morphology and histochemistry of the insular apparatus in experimental guinea
      pig steroid diabetes, especially under actinomycin D influence].

PMID- 4357676
TI  - [Islands of Langerhans in vitro. VII. Comparative studies on insulin secretion
      stimulation by various substrates in the rat].

PMID- 4357677
TI  - A study on the role of pituitary ACTH in the aldosterone production of sodium
      depleted rats.

PMID- 4357678
TI  - Familial congenital adrenal hypoplasia.

PMID- 4357679
TI  - Adrenocortical responsiveness after long-term corticosteroid therapy in childhood
      nephrosis.

PMID- 4357681
TI  - Letter: A phosphodiesterase from Enterobacter aerogenes.

PMID- 4357680
TI  - Alteration of binding specificity of murine myeloma protein-315 to 2,4
      dinitrophenyl and 2,4,6-trinitrophenyl ligands.

PMID- 4357682
TI  - Surface markers on human B and T lymphocytes. II. Presence of Epstein-Barr virus
      receptors on B lymphocytes.
AB  - Human peripheral lymphocytes were investigated for receptors binding Epstein-Barr
      virus (EBV) because of the regular association of this virus with infectious
      mononucleosis and Burkitt's lymphoma. This was done by a cytoadherence technique
      where virus-producing cells, displaying fresh viral determinants in their
      cytoplasmatic membrane, were mixed with lymphocytes. Unfractionated lymphocytes
      were found to adhere to these cells in contrast to column-purified T lymphocytes.
      The specificity of the binding was confirmed by blocking experiments that showed
      that sera containing high titers of antibodies directed against the virus could
      partially inhibit the adherence in contrast to low-titer sera. It is concluded
      that B lymphocytes, in contrast to T lymphocytes, have receptors for EBV. In a
      second line of experiments it was found that established human lymphoblastoid
      lines that carry the EBV genome had receptors characteristic for B lymphocytes
      and did not form T-lymphocyte rosettes. In contrast, a line of known T-lymphocyte
      origin that did not carry the EBV genome had receptors characteristic for T
      lymphocytes. EBV-transformed simian lymphoblastoid lines had surface markers
      indicating a B-lymphocyte origin in contrast to HVS-transformed simian lines that
      lacked surface immunoglobulin but carried receptors for sheep red blood cells.

PMID- 4357683
TI  - Comparison of the yield of infectious virus from clones of human and simian
      lymphoblastoid lines transformed by Epstein-Barr virus.
AB  - Three lymphoblastoid cell lines, of human, squirrel monkey, and marmoset origin,
      all transformed by the same strain of Epstein-Barr virus (EBV), differed markedly
      in their content of infectious virus. Single cell clones were obtained from each
      line to learn whether these differences were dependent upon factors shared by all
      cells in each line or upon factors present only in a proportion of the total cell
      population. A total of 17 primary clones were examined: 6 human, 6 squirrel
      monkey, and 5 marmoset. Cloning efficiency on human placental cell feeder layers
      varied from 16 to 24%. EBV antiserum, present in the cloning suspension, was
      shown to neutralize all extracellular virus. 15 of the 17 clones released EBV as
      measured by the transformation assay. Titers of infectious virus released by
      daughter clones paralleled titers of virus in the parent line. The median virus
      titers from human, squirrel monkey, and marmoset clones were respectively
      10(1.5), 10(3.0), and 10(4.3) 50% transforming doses per 0.2 ml. The median yield
      of virus from clones of the three species was, respectively, 4, 96, and 786
      transforming units per 1,000 cells containing viral capsid antigen. Two
      nonproducer clones (one human and one squirrel monkey) did not release infectious
      virus after treatment with 5'-bromodeoxyuridine, or with X ray followed by co
      cultivation with marmoset leukocytes. The nonproducer clones could not be
      superinfected by biologically active EBV. These results show that differences in
      production of infectious EBV among the lines tested are reflected in the majority
      of cells of these lines. The data imply that the mechanism for regulation of the
      expression of the EBV genome is cellular rather than viral in origin. There are
      presumably genetic differences among primate species in this regulatory process.

PMID- 4357684
TI  - Adaptations of energy metabolism in the cultivated macrophage.
AB  - Adaptive changes in energy metabolism, as reflected by pyruvate kinase and
      cytochrome oxidase activities, were examined during in vitro differentiation of
      the cultivated macrophage. Serum concentrations of tissue culture media, which
      directly influence endocytic activity, and ambient oxygen tension were both shown
      to influence pyruvate kinase and cytochrome oxidase activities. Cells maintained
      in high serum concentrations (30% newborn calf serum [NBCS]) exhibited a 300-400%
      increase in pyruvate kinase activity and a 40% increase in cytochrome oxidase
      activity, whereas cells maintained in low serum concentrations (2% NBCS)
      exhibited a lesser increase (65%) in pyruvate kinase activity and no change in
      cytochrome oxidase activity. Anaerobiosis resulted in additional alterations in
      pyruvate kinase and cytochrome oxidase activities. Cells maintained for 48-72 h
      under anaerobic conditions exhibited a 500-600% increase in pyruvate kinase
      activity and a 40% decrease in cytochrome oxidase activity. Increased pyruvate
      kinase activity was dependent on continued protein synthesis. Enzyme increases
      occurred in anaerobically cultured cells despite an overall reduction in cell
      protein synthesis. It is suggested that adaptive changes in pyruvate kinase and
      cytochrome oxidase activity resulting from alterations in either serum
      concentration or ambient oxygen tension are regulated by two independent
      mechanisms. One mechanism is aimed at providing energy for endocytic activity and
      the other in compensating for impaired oxidative metabolism during anaerobiosis.

PMID- 4357685
TI  - A suppression of cellular immunity in patients with multiple sclerosis.

PMID- 4357686
TI  - Preparation and characterization of an immuno-electron microscope tracer
      consisting of a heme-octapeptide coupled to fab.
AB  - A heme-octapeptide (mol wt 1,550) has been obtained from cytochrome c by
      successive pepsin and trypsin hydrolysis and purified by gel filtration and
      countercurrent distribution. It possesses peroxidatic activity characterized by
      an apparent K(m) of 0.2 M, an apparent v(max) of 4 mmol/min per mg of peptide,
      and a pH optimum of 7.0. Using a novel two-step conjugation procedure, the heme
      octapeptide was coupled to rabbit Fab antibody fragments by first derivatizing it
      with the N-hydroxysuccinimide ester of p-formylbenzoic acid and subsequently
      allowing it to form a Schiff base with the amino groups of Fab. Stable covalent
      linkages were then obtained by reduction of the Schiff bases with sodium
      borohydride. The conjugate consists of approximately 2 heme-octapeptides attached
      to each Fab molecule. The molecular weight is 45,000 daltons when coupled to
      sheep Fab and 50,000 daltons with a Stokes radius of 32 A, when conjugated to
      rabbit Fab. Its peroxidatic activity is characterized by an apparent K(m) of 0.4
      M, an apparent v(max) of 0.4 mmol/min and per mg of attached heme-octapeptide and
      a pH optimum of 7.0. The conjugate has been used for the localization at the
      electron microscope level of secretory immunoglobulins in the mammary gland of
      lactating rabbits.

PMID- 4357687
TI  - Renin content in subcellular fractions of normal rat kidney extract.

PMID- 4357688
TI  - [Management of a patient with insuloma].

PMID- 4357689
TI  - Role of cyclic AMP in the action of antidiuretic hormone on kidney.

PMID- 4357690
TI  - Uptake of estradiol by the rat pineal organ. Effects of cervical sympathectomy,
      stage of the estrous cycle and estradiol treatment.

PMID- 4357691
TI  - Synthesis and toxicity evaluation of aflatoxin P.

PMID- 4357692
TI  - New applications of electron spin resonance to problems in biochemistry and
      pharmacology.

PMID- 4357693
TI  - The influence of p,p'-DDT, alpha-chlordane, heptachlor and endrin on hepatic and
      renal carbohydrate metabolism and cyclic AMP-adenyl cyclase system.

PMID- 4357695
TI  - Enigma and dilemma of the pulmonary nodule.

PMID- 4357694
TI  - Aldosterone: review of its physiology and diagnostic aspects of primary
      aldosteronism.

PMID- 4357697
TI  - [Clinical problems in Wilms' tumors in childhood].

PMID- 4357696
TI  - Dissociation between human platelet agglomerating activity and factor VIII
      procoagulant activity of bovine plasma preparations by chemical treatment. II.
      Effect of periodate oxidation.

PMID- 4357699
TI  - [Hemocoagulation in malignant neoplasms in children].

PMID- 4357698
TI  - [Carcinoma of the breast under estrogen-treatment for prostatic carcinoma
      (author's transl)].

PMID- 4357701
TI  - [Change in the DNA content of tumor cell nuclei in the process of "progression"
      of induced hepatoma].

PMID- 4357700
TI  - [Glutathione reductase activity in human and animal tumors].

PMID- 4357702
TI  - [Results of a comparative study of the efficacy of treatment of early forms of
      breast neoplasms by different methods].

PMID- 4357703
TI  - [In vitro cytotoxicity of rabbit and guinea pig antisera against the Zajdela
      ascites hepatoma in the rat].

PMID- 4357704
TI  - Feline viral infections.

PMID- 4357706
TI  - Ultrastructural and histochemical demonstration of myoepithelium in mixed tumors
      of the canine mammary gland.

PMID- 4357705
TI  - Feline viral rhinotracheitis (FVR).

PMID- 4357707
TI  - Immunologic response of the bovine fetus to inactivated infectious bovine
      rhinotracheitis-infectious pustular vulvovaginitis virus.

PMID- 4357708
TI  - Role of horse fly (Tabanus fuscicostatus Hine) and stable fly (Stomoxys
      calcitrans L.) in transmission of equine infectious anemia to ponies in
      Louisiana.

PMID- 4357709
TI  - Lithium carbonate and sleep in affective disorders. Further considerations.

PMID- 4357711
TI  - An antimycin A- and cyanide-resistant variant of Candida utilis arising during
      copper-limited growth.
AB  - 1. During copper-limited growth of Candida utilis in continuous culture on a non
      fermentable carbon and energy source there is a selective pressure favouring the
      emergence of variants that are less dependent on copper. 2. We describe the
      properties of such a variant that by-passes cytochrome oxidase (EC 1.9.3.1) by
      utilizing an alternative oxidase communicating with the respiratory chain at
      about the level of cytochrome b. 3. Both direct studies of isolated mitochondria
      and calculations based on growth parameters showed that only one of the normal
      three phosphorylation sites was active. This site was localized between NADH and
      the cytochromes. 4. Growth of the variant with copper-supplemented media resulted
      in the return of cytochrome oxidase but not the loss of the alternative oxidase.
      5. The alternative oxidase is inhibited by substituted benzhydroxamic acids. 6.
      Submitochondrial particles from the variant did not exhibit any novel electron
      paramagnetic-resonance-spectroscopy features at about g=2.0 either at 80 degrees
      K or 12 degrees K.

PMID- 4357710
TI  - Respiration-driven proton translocation by yeast mitochondria with differing
      efficiencies of oxidative phosphorylation.
AB  - Measurements were made of the stoicheiometry of proton translocation coupled to
      respiration in mitochondria from Candida utilis where the number of functional
      energy-conservation sites between intramitochondrial NADH and oxygen was one in a
      mutant with a novel oxidase (Downie & Garland, 1972), two in sulphate-deficient
      cells (Haddock & Garland, 1971) or three in glycerol-limited cells (Light &
      Garland, 1971). The stoicheiometries of protons translocated per atom of oxygen
      utilized (i.e. -->H(+)/2e(-) ratio; Mitchell, 1966) were close to 2.0, 4.0 and
      6.0 respectively. Thus by using the same substrate (intramitochondrial NADH) and
      oxygen throughout, the -->H(+)/2e(-) ratio is shown to be 2.0 per energy
      conservation site when the number of such sites is varied from one to three.

PMID- 4357712
TI  - Changes in enzyme activities in tissues of rats exposed to hypoxia.
AB  - Rats were exposed to various degrees of hypoxia and enzyme activities in their
      tissues were determined. In general, oxidative metabolism was not increased in
      response to hypoxia, nor was anaerobic metabolism. Physiological and anatomical
      changes were concluded to be more important than changes in cellular enzyme
      activities in the overall adaptation to acute hypoxia.

PMID- 4357713
TI  - Cell-surface mucosubstances from trypsin diaggregation of normal and virus
      transformed lines of baby-hamster kidney cells.
AB  - Cell disaggregation by trypsin solubilizes significantly less mucosubstance from
      the surface of polyoma-virus-transformed baby-hamster kidney cells than from the
      same non-transformed cell line. The mucosubstance, which consists of both acid
      mucopolysaccharides and mucoproteins, also differs qualitatively in the two cell
      lines.

PMID- 4357714
TI  - Biochemical effects of the porphyrinogenic drug allylisopropylacetamide. A
      comparative study with phenobarbital.
AB  - Successive administrations of allylisopropylacetamide, a potent porphyrinogenic
      drug, increase liver weight, microsomal protein and phospholipid contents. There
      is an increase in the rate of microsomal protein synthesis in vivo and in vitro.
      The drug decreases microsomal ribonuclease activity and increases NADPH
      cytochrome c reductase activity. Phenobarbital, which has been reported to
      exhibit all these changes mentioned, is a weaker inducer of delta
      aminolaevulinate synthetase and increases the rate of haem synthesis only after a
      considerable time-lag in fed female rats, when compared with the effects observed
      with allylisopropylacetamide. Again, phenobarbital does not share the property of
      allylisopropylacetamide in causing an initial decrease in cytochrome P-450
      content. Haematin does not counteract most of the biochemical effects caused by
      allylisopropylacetamide, although it is quite effective in the case of
      phenobarbital. Haematin does not inhibit the uptake of [2
      (14)C]allylisopropylacetamide by any of the liver subcellular fractions.

PMID- 4357715
TI  - Glucose metabolism in the newborn rat. Hormonal effects in vivo.
AB  - 1. The concentrations of liver glycogen and plasma d-glucose were measured in
      caesarian-delivered newborn rats at time-intervals up to 3h after delivery after
      treatment of the neonatal rats with glucagon, dibutyryl cyclic AMP, cortisol or
      cortisol+dibutyryl cyclic AMP. Glycogenolysis was promoted by glucagon or
      dibutyryl cyclic AMP in the third hour after birth but not at earlier times.
      Cortisol and dibutyryl cyclic AMP together (but neither agent alone) promoted
      glycogenolysis in the second hour after birth, but no hormone combination was
      effective in the first postnatal hour. 2. The specific radioactivity of plasma d
      glucose was measured as a function of time for up to 75 min after the
      intraperitoneal injection of d-[6-(14)C]glucose and d-[6-(3)H]glucose into
      newborn rats at delivery and after treatment with glucagon or actinomycin D.
      Glucagon-mediated hyperglycaemia at this time was due to an increased rate of
      glucose formation and a decreased rate of glucose utilization. Actinomycin D
      prevented glucose formation and accelerated the rate of postnatal hypoglycaemia.
      3. The specific radioactivity of plasma l-lactate and the incorporation of (14)C
      into plasma d-glucose was measured as a function of time after the
      intraperitoneal injection of l-[U-(14)C]lactate into glucagon- or actinomycin D
      treated rats immediately after delivery. The calculated rates of lactate
      formation were unchanged by either treatment, but lactate utilization was
      stimulated by glucagon administration. Glucagon stimulated and actinomycin D
      diminished (14)C incorporation into plasma d-glucose. 4. The factors involved in
      the initiation of glycogenolysis and gluconeogenesis in the rat immediately after
      birth are discussed.

PMID- 4357716
TI  - Microbial metabolism of amino alcohols. Metabolism of ethanolamine and 1
      aminopropan-2-ol in species of Erwinia and the roles of amino alcohol kinase and
      amino alcohol o-phosphate phospho-lyase in aldehyde formation.
AB  - 1. Growth of Erwinia carotovora N.C.P.P.B. 1280 on media containing 1-aminopropan
      2-ol compounds or ethanolamine as the sole N source resulted in the excretion of
      propionaldehyde or acetaldehyde respectively. The inclusion of (NH(4))(2)SO(4) in
      media prevented aldehyde formation. 2. Growth, microrespirometric and enzymic
      evidence implicated amino alcohol O-phosphates as aldehyde precursors. An
      inducibly formed ATP-amino alcohol phosphotransferase was partially purified and
      found to be markedly stimulated by ADP, unaffected by NH(4) (+) ions and more
      active with ethanolamine than with 1-aminopropan-2-ol compounds. Amino alcohol O
      phosphates were deaminated by an inducible phospho-lyase to give the
      corresponding aldehydes. This enzyme, separated from the kinase during
      purification, was more active with ethanolamine O-phosphate than with 1
      aminopropan-2-ol O-phosphates. Activity of the phospho-lyase was unaffected by a
      number of possible effectors, including NH(4) (+) ions, but its formation was
      repressed by the addition of (NH(4))(2)SO(4) to growth media. 3. E. carotovora
      was unable to grow with ethanolamine or 1-aminopropan-2-ol compounds as sources
      of C, the production of aldehydes during utilization as N sources being
      attributable to the inability of the microbe to synthesize aldehyde
      dehydrogenase. 4. Of seven additional strains of Erwinia examined similar results
      were obtained only with Erwinia ananas (N.C.P.P.B. 441) and Erwinia milletiae
      (N.C.P.P.B. 955).

PMID- 4357718
TI  - [Changes in the diameter of some cell strains transformed by adenovirus and SV 40
      virus, studied in vitro and in vivo].

PMID- 4357717
TI  - Hormonal regulation of glycogen metabolism in neonatal rat liver.
AB  - 1. The development of active and inactive phosphorylase was determined in rat
      liver during the perinatal period. No inactive form could be found in tissues
      from animals less than 19 days gestation or older than the fifth postnatal day.
      2. The regulation of phosphorylase in organ cultures of foetal rat liver was
      examined. None of the agents examined [glucagon, insulin or dibutyryl cyclic AMP
      (6-N,2'-O-dibutyryladenosine 3':5'-cyclic monophosphate)] changed the amount of
      phosphorylase activity. 3. Glycogen concentration in these explants were
      nevertheless decreased more than twofold by 4h of incubation with glucagon or
      dibutyryl cyclic AMP. Incubation with insulin for 4h increased the glycogen
      content twofold. 4. Glycogen synthetase activity was examined in these explants.
      I-form activity (without glucose 6-phosphate) was found to decrease by a factor
      of two after 4h of incubation with dibutyryl cyclic AMP, whereas I+D activity
      (with glucose 6-phosphate) remained nearly constant. Incubation for 4h with
      insulin increased I-form activity threefold, with only a slight increase in I+D
      activity. 5. When explants were incubated with insulin followed by addition of
      dibutyryl cyclic AMP, the effects of insulin on glycogen concentration and
      glycogen synthetase activity were reversed. 6. These results indicate that the
      regulation of glycogen synthesis may be the major factor in the hormonal control
      of glycogen metabolism in neonatal rat liver.

PMID- 4357720
TI  - Interaction of Sendai virus with human erythrocytes. I. The ultrastructure of
      untreated and pyridine-treated virions and their relationship with erythrocyte
      surface during hemagglutination.

PMID- 4357719
TI  - [Intravaginal infection of mice with herpes simplex virus of 2 subtypes].

PMID- 4357721
TI  - Interaction of Sendai virus with human erythrocytes. II. The fusion reactions.

PMID- 4357723
TI  - Pharmacologic and toxicologic studies with the polymyxins. I. A gas
      chromatographic procedure for the analysis of colistin in urine by its content of
      D-leucine.

PMID- 4357722
TI  - Adenosine metabolism in Micrococcus sodonensis.

PMID- 4357724
TI  - Pharmacologic and toxicologic studies with the polymyxins. II. Comparative
      pharmnacologic studies of the sulfate and methanesulfonate salts of polymyxin B
      and colistin in dogs.

PMID- 4357725
TI  - Pharmacologic and toxicologic studies with the polymyxins. 3. Consideration
      regarding clinical use in dogs.

PMID- 4357727
TI  - Effects of mebutamate on the electroencephalographic sleep profile.

PMID- 4357726
TI  - [Active amine and hypothalamic cyclic AMP].

PMID- 4357728
TI  - [Malignant tumours in childhood (author's transl)].

PMID- 4357729
TI  - Elevation of plasma glucose levels by mammalian ACTH in the spiny dogfish shark
      (Squalus acanthias).

PMID- 4357730
TI  - Effects of ACTH on the pituitary-interrenal axis and abundance of white blood
      cell types in juvenile coho salmon, Oncorhynchus kisutch.

PMID- 4357731
TI  - Sodium-retaining bioassay of prolactin in the intact teleost Tilapia mossambica
      acclimated to sea water.

PMID- 4357732
TI  - Pituitary regulation of serum calcium levels in the killifish, Fundulus
      heteroclitus L.

PMID- 4357733
TI  - Cyclic adenosine 3':5'-monophosphate-dependent protein kinase.

PMID- 4357734
TI  - Kinetic studies of the inhibition of muscle phosphorylase phosphatase.

PMID- 4357735
TI  - Kinetic studies of the activation of muscle phosphorylase phosphatase.

PMID- 4357736
TI  - Alpha-keto acid dehydrogenase complexes. XX. A kinetic study of the pyruvate
      dehydrogenase complex from bovine kidney.

PMID- 4357737
TI  - Similarity of the active site of phosphorylation of the adenosine triphosphatase
      from transport of sodium and potassium ions in kidney to that for transport of
      calcium ions in the sarcoplasmic reticulum of muscle.

PMID- 4357738
TI  - Human plasma high density lipoprotein. Interaction of the cyanogen bromide
      fragments from apolipoprotein glutamine II (A-II) with phosphatidylcholine.

PMID- 4357739
TI  - Antifreeze glycoprotein from an Antarctic fish. Effects of chemical modifications
      of carbohydrate residues on antifreeze and antilectin activities.

PMID- 4357740
TI  - Concerted feedback inhibition. Purification and some properties of aspartokinase
      from Pseudomonas fluorescens.

PMID- 4357741
TI  - Concerted feedback inhibition. Modifier-induced oligomerization of the
      Pseudomonas fluorescens aspartokinase.

PMID- 4357742
TI  - Oxidation of 21-dehydrocorticosteroids to steroidal 20-Oxo-21-oic acids by an
      aldehyde dehydrogenase of sheep adrenal.

PMID- 4357743
TI  - Studies on bovine hepatic fructose 1,6-diphosphatase. Substrate inhibition and
      the kinetic mechanism.

PMID- 4357744
TI  - Chicken liver phosphofructokinase. II. Cold inactivation.

PMID- 4357745
TI  - The development of a TRIC agent (Chlamydia trachomatis) and its associated
      polysaccharide in suspended cell cultures.

PMID- 4357746
TI  - Interaction between viruses and platelets: requirement of haemolytic activity for
      platelet aggregation induced by paramyxoviruses.

PMID- 4357747
TI  - Characterization of temperature-sensitive mutants of SV40.

PMID- 4357748
TI  - Synthesis of ribonucleic acids in KB cells infected with rhinovirus type 14.

PMID- 4357749
TI  - The effect of rifampicin, actinomycin D and mitomycin C on poliovirus and foot
      and-mouth disease virus replication.

PMID- 4357750
TI  - Homology of surface receptors for poliovirus on mammalian cell lines.

PMID- 4357751
TI  - Inhibition by interferon of polyoma virus-induced cell DNA synthesis in mouse
      peritoneal macrophages.

PMID- 4357752
TI  - The distribution of virus proteins in BHK 21 cells infected with vesicular
      stomatitis virus (Indiana C).

PMID- 4357753
TI  - The lipid content of two iridescent viruses.

PMID- 4357754
TI  - The morphology, morphogenesis, and serological characterization of the
      rhabdoviruses Navarro, Kwatta, and Mossuril.

PMID- 4357755
TI  - Cytochalasin B-induced activation in the synthesis of L-cell virus particles.

PMID- 4357756
TI  - Characterization of segmented double-helical RNA from bacteriophage phi6.

PMID- 4357757
TI  - A human cell line from a pleural effusion derived from a breast carcinoma.

PMID- 4357758
TI  - In vitro cultivation of human tumors: establishment of cell lines derived from a
      series of solid tumors.

PMID- 4357759
TI  - Case-control study of Hodgkin's disease. II. Herpesvirus group antibody titers
      and HL-A type.

PMID- 4357760
TI  - Limited capacity for motor activity as a cause for declining food intake in
      cancer.

PMID- 4357761
TI  - In vivo and in vitro studies on the morphogenesis of tumors induced by murine
      sarcoma virus (Harvey).

PMID- 4357762
TI  - Combined neoplastic effects of vaccinia virus and 3-methylcholanthrene. 3.
      Susceptibility and resistance in transplanted mouse skin.

PMID- 4357763
TI  - Analysis by immunoelectron microscopy of type-C viruses associated with primary
      and short-term transplanted mouse plasma cell tumors.

PMID- 4357764
TI  - Malignant mouse-liver tumors resembling human hepatoblastomas.

PMID- 4357766
TI  - Comparison of three mammary tumor viruses in genetically similar susceptible
      mice.

PMID- 4357765
TI  - Enzyme activities and extrinsic proteins in plasma membranes from normal liver
      and Morris hepatoma 5123tc.

PMID- 4357767
TI  - Quantitative lung colony assay for tumor immunity in mice.

PMID- 4357768
TI  - Acute alcoholic myopathy. Enzyme histochemistry and electron microscopic
      findings.

PMID- 4357769
TI  - Sural nerve conduction velocity in peripheral neuropathies and subacute myelo
      optico-neuropathies (SMON).

PMID- 4357771
TI  - Cyclic nucleotides as intracellular mediators of the expression of antigen
      sensitive cells.

PMID- 4357772
TI  - Phagocytic release and activation of human leukocyte procollagenase.

PMID- 4357770
TI  - [Effect on animals of continuous and intermittent exposure to carbon monoxide].

PMID- 4357773
TI  - [Blood serum immunoglobulins in multiple sclerosis].

PMID- 4357774
TI  - [Polyneuropathy in liver cirrhosis. Clinical and electrophysiological
      assessment].

PMID- 4357775
TI  - [Transfer factor of cellular immunity. Preliminary therapeutic trials during
      specific immunologic deficiencies of an antigen in human clinical practice].

PMID- 4357776
TI  - Psycho-analytic group interview and short-term group psychotherapy with post
      myocardial infarction patients.

PMID- 4357777
TI  - [Hepatitis epidemiology in Switzerland].

PMID- 4357778
TI  - [Case of malignant chemodectoma of the posterior mediastinum].

PMID- 4357779
TI  - [Characteristics of the clinical features of adenoviral diseases in children,
      depending on the virus serotype].

PMID- 4357780
TI  - [Certain clinico-immunological comparisons in children with respiratory diseases
      in the 1st month of life].

PMID- 4357781
TI  - [Certain characteristics of humoral immunity in children with chronic pneumonia
      and bronchial asthma].

PMID- 4357782
TI  - [Modern virus diagnostics].

PMID- 4357783
TI  - A sensitive in vitro bioassay method for luteinizing hormone (LH) activity.

PMID- 4357784
TI  - Stimulating effect of dibutyryl cyclic adenosine 3',5' monophosphate on protein
      synthesis in a thyroidal cell-free system at low potassium and sodium
      concentrations.

PMID- 4357786
TI  - Fine structure of the urinary bladder of the bullfrog. (Rana catesbiana).

PMID- 4357785
TI  - Freeze-fracture studies of gap junctions of normal and neoplastic astrocytes.

PMID- 4357787
TI  - Phagocytosis of supernumerary spermatozoa by two-cell embryos.

PMID- 4357788
TI  - Bacterial endophthalmitis after cataract extraction. II. Incidence in 36,000
      consecutive operations with special reference to preoperative topical
      antibiotics.

PMID- 4357789
TI  - Collagenase inhibitors in Pseudomonas keratitis. Adjuncts to antibiotic therapy
      in rabbits.

PMID- 4357790
TI  - Viral isolate in superficial punctate keratitis.

PMID- 4357792
TI  - Vitamin C--effects on the Na+, K+ adenosine triphosphate phosphohydrolase
      complexes of several tissues.

PMID- 4357791
TI  - Adaptive response of hepatic carbohydrate metabolism to oral administration of
      p,p'-1,1,1-trichloro-2,2-bis (p-chlorophenyl)ethane in rats.

PMID- 4357793
TI  - Inhibition of purine biosynthesis de novo in sarcoma 180 ascites cells by
      mercapto and seleno purine analogs.

PMID- 4357794
TI  - Action of organophosphorus compounds on cell organelles. I. Effect of tetraethyl
      dithio pyrophosphate on lysosomal hydrolases.

PMID- 4357795
TI  - Effect of cyclic nucleotides on activity of cyclic 3',5'-adenosine monophosphate
      phosphodiesterase.

PMID- 4357796
TI  - [Ultrastructural changes in thyroid gland cells during different schedules of
      intermedin administration].

PMID- 4357797
TI  - Leukopenia, leukoagglutinins, and low IgM in a family with severe febrile
      illnesses.

PMID- 4357798
TI  - Studies of the Epstein-Barr virus-host relationship: autochthonous and allogeneic
      lymphocyte stimulation by lymphoblast cell lines in mixed cell culture.

PMID- 4357799
TI  - Identification and partial characterization of specific estrogen receptors in the
      vole (Microtus montanus).

PMID- 4357800
TI  - Species specificity of the inhibition of adenylate cyclase activation by products
      of ACTH-stimulated fat cells.

PMID- 4357802
TI  - Phosphatase activity in epiphyseal cartilage of the chicken (Gallus gallus).

PMID- 4357801
TI  - The lactate dehydrogenase system in the heart and skeletal muscle of fish: a
      comparative study.

PMID- 4357804
TI  - A spin-label study of horse erythrocyte carbonic anhydrases C and D.

PMID- 4357803
TI  - Effects of estradiol and testosterone on the immature female chicken (Gallus
      domesticus). II. Immunodiffusional patterns of yolk lipoproteins in the liver and
      plasma.

PMID- 4357805
TI  - Metabolism in porifera. II. Distribution of sterols.

PMID- 4357806
TI  - Pathogenesis of genetic diabetes mellitus: further development of a hypothesis.

PMID- 4357807
TI  - In vitro biosynthesis of human placental lactogen (HPL) by chorionic tissue and
      the diagnostic value of HPL in trophoblastic disease.

PMID- 4357808
TI  - Radiation myelopathy.

PMID- 4357809
TI  - Pathohistological findings in the peripheral nervous system (nn. ischiadici)
      after experimental carbon tetrachloride intoxication in bastard rabbits.

PMID- 4357810
TI  - Protein kinase and cyclic AMP-binding activities in liver and adipose tissue of
      normal, streptozotocin-diabetic and adrenalectomized rats.

PMID- 4357811
TI  - Sequence analysis of polyribonucleotides by continuous directional degradation--a
      study of the course of the reaction at nucleotide concentrations between 10-7 and
      10-5 molar.

PMID- 4357812
TI  - Biosynthesis of sideramines in fungi. Fusigen synthetase from extracts of
      Fusarium cubense.

PMID- 4357813
TI  - Evaluation of the energetics of cytochrome C oxidase in the absense of cytochrome
      C.

PMID- 4357814
TI  - Poly (ADP-ribose) glycohydrolase in mouse fibroblast cells (LS cells).

PMID- 4357815
TI  - The inhibition of Azotobacter vinelandii terminal oxidases by cyanide.

PMID- 4357816
TI  - Improvement of the spin-labelling technique by the use of a radioactive spin
      label.

PMID- 4357817
TI  - Two ACTH species in rat pituitary gland.

PMID- 4357818
TI  - Pyruvate metabolism and nitrogen fixation in Azotobacter.

PMID- 4357819
TI  - Novel type of catabolite repression in the pathway of gamma-aminobutyrate
      breakdown in Escherichia coli K-12.

PMID- 4357820
TI  - Solid-phase Edman degradation of a protein: N-terminal sequence of cytochrome c
      from Candida krusei.

PMID- 4357822
TI  - Cytochromes of two methane-utilizing bacteria.

PMID- 4357821
TI  - Stimulation of adipose tissue triglyceride lipase activity after in vivo
      administration of dibutyryl cyclic AMP or norepinephrine.

PMID- 4357823
TI  - The solid-phase synthesis of human and monkey beta-melanotropins.

PMID- 4357825
TI  - Cyclic AMP metabolism in asthma: studies with leukocytes and lymphocytes.

PMID- 4357824
TI  - A preparative method for the isolation of carboxyl terminal tryptic peptides from
      proteins.

PMID- 4357826
TI  - Effects of synthetic ACTH on corticosteroid-induced growth suppression.

PMID- 4357827
TI  - Plasma-cell mastitis: case report.

PMID- 4357828
TI  - Muscle fiber type, rigor development and bone strength in dobule muscled cattle.

PMID- 4357830
TI  - Metabolism of biuret by ruminants: in vivo and in vitro studies and the role of
      protozoa in biuretolysis.

PMID- 4357829
TI  - Metabolic pathways of biuret degradation and formation of a biuret-complex in the
      rumen.

PMID- 4357831
TI  - Letter: Optimal postfixation washing time for ultrastructural demonstration of
      glucose 6-phosphatase activity.

PMID- 4357833
TI  - Fine structure of the contractile vacuole pore in Paramecium.

PMID- 4357832
TI  - Conformation of coenzyme fragments when bound to lactate dehydrogenase.

PMID- 4357834
TI  - Breeding of European hamsters.

PMID- 4357835
TI  - Establishment by selective inbreeding of the IVCS strain and related sister
      strains of the mouse, demonstrating regularly repeated 4-day estrous cycles.

PMID- 4357836
TI  - Simian virus 16 associated with an epizootic of obscure neurologic disease.

PMID- 4357837
TI  - Preventive medicine in anthropoids: parasite control.

PMID- 4357838
TI  - Maintenance and husbandry of armadillo colonies.

PMID- 4357839
TI  - Humoral immune response of the adult chinchilla.

PMID- 4357840
TI  - The pathogenesis of the alopecia due to hair-chewing in mice.

PMID- 4357842
TI  - Establishment of a helminth-free opossum colony.

PMID- 4357841
TI  - Protein requirement of growing gerbils.

PMID- 4357843
TI  - An epizootic of protozoan enteritis in a closed mouse colony.

PMID- 4357844
TI  - Blood acid-base status in normal albino rats.

PMID- 4357845
TI  - A durable housing facility for reptiles.

PMID- 4357846
TI  - An apparatus for anesthetizing small laboratory rodents.

PMID- 4357847
TI  - Pediculosis of spider monkeys: a case report with zoonotic implications.

PMID- 4357848
TI  - Versatile cage for environmental protection housing of research animals.

PMID- 4357849
TI  - Measurement of blood cholinesterase activity in laboratory animals utilizing
      dimethylbutyl acetate as a substrate.

PMID- 4357851
TI  - Indirect measurement of arterial blood pressure in the laboratory pony.

PMID- 4357850
TI  - A combination sterilizing chamber and transfer and housing isolator for use in
      gnotobiotic laboratories.

PMID- 4357852
TI  - Hematologic changes to 60 days of age in clinically normal beagles.

PMID- 4357854
TI  - A case of conjoined twins in the Sprague-Dawley rat.

PMID- 4357853
TI  - Microbial flora and viral contact status of Chinese hamsters (Cricetulus
      griseus).

PMID- 4357856
TI  - The Epstein-Barr virus carrier state in infectious mononucleosis.

PMID- 4357855
TI  - Pathogenesis of hereditary vitamin-D-dependent rickets. An inborn error of
      vitamin D metabolism involving defective conversion of 25-hydroxyvitamin D to 1
      alpha,25-dihydroxyvitamin D.

PMID- 4357858
TI  - Morphine blockade of amino acid putative transmitters on cat spinal cord sensory
      interneurones.

PMID- 4357857
TI  - Strand orientation of SV40 transcription in cells infected by non-defective
      adenovirus 2-SV40 hybrid viruses.

PMID- 4357860
TI  - Effect of aminoglutethimide and glutethimide on the pituitary-adrenal system.

PMID- 4357861
TI  - Adrenocortical influences upon the extinction of an appetitive runway response.

PMID- 4357859
TI  - Electrophysiological investigation of natural sleep and waking in turtles and
      hens.

PMID- 4357862
TI  - Suppression of pituitary-adrenal activity and shock-induced fighting in rats.

PMID- 4357863
TI  - Hydration releases inhibition of feeding produced by intracranial angiotensin.

PMID- 4357864
TI  - In vitro translation of oogenetic messenger RNA of sea urchin eggs and
      picornavirus RNA with a cell-free system from sarcoma 180.
AB  - A cell-free protein-synthesizing system prepared from mouse sarcoma 180 was
      characterized by use of RNA from mengo virus and sea urchin egg. In the presence
      of exogenous mammalian transfer RNA, total sea urchin egg RNA and mengo RNA
      direct incorporation of [(3)H]leucine into acid-insoluble material. The system is
      extremely efficient in that a stimulation of 100-times over background can be
      obtained. Studies with formylmethionyl-transfer RNA, as well as with inhibitors
      of initiation, indicate that multiple initiation occurs; further, 85-90% of all
      chains made in vitro are subsequently released from ribosomes. An average
      translation time of 3.5 min was determined with messenger RNA of sea urchin egg,
      and product analysis indicates that high-molecular-weight products (greater than
      50,000 molecular weight) are being made in vitro. Sequences of sea urchin egg RNA
      containing poly(A) act as messenger RNA.

PMID- 4357865
TI  - Homology between type-C viruses of various species as determined by molecular
      hybridization.
AB  - Two strains of feline leukemia virus, two endogenous feline type-C viruses
      (RD/CCC group), several endogenous and laboratory strains of murine "leukemia"
      virus, two rat viruses, two primate viruses (woolly monkey and gibbon ape), as
      well as hamster, pig, and avian type-C viruses were examined for their
      relatedness to one another by molecular hybridization. The extent of nucleic-acid
      homology was determined by hybridization of the various viral RNAs to a [(3)H]DNA
      product synthesized from each virus. Among the murine type-C viruses (Rauscher,
      Kirsten, AT-124, and endogenous BALB/c virus) a high degree of homology is
      observed, although the viruses are not identical. The two primate viruses are
      also closely related to one another. The feline, rat, hamster, and pig endogenous
      viruses can be readily distinguished from one another and from the murine and
      primate viruses since their DNA products share very little or no nucleic-acid
      homology. However, the murine and primate type-C virus groups possess a
      surprising degree of relatedness. Feline type-C viruses fall into two distinct
      groups, the feline leukemia virus group and the RD-114/CCC group, with little
      detectable nucleic-acid homology between them. Infection of feline or rat cells
      with type-C virus results in production of the endogenous type-C virus of the
      species along with the infecting virus.

PMID- 4357866
TI  - Altered growth behavior of malignant cells associated with changes in externally
      labeled glycoprotein and glycolipid.
AB  - By use of galactose oxidase (EC 1.1.3.9), followed by reduction with tritiated
      sodium borohydride, the surface structures of transformed 3T3 and NIL cells,
      under ordinary growth conditions, were characterized by (i) deletion of the
      normally existing glycoprotein label and (ii) appearance or increase of a new
      glycoprotein label. NIL cells had a galactoprotein label with molecular weight
      200,000 that was deleted in NIL cells transformed by polyoma virus. 3T3 cells had
      a glycoprotein label with molecular weight of 30,000 that was lost after
      transformation. Glycoproteins of transformed 3T3 cells, with molecular weight
      105,000, and those of transformed NIL cells, with molecular weight 85,000, were
      not labeled in normal confluent cells, but became labeled after trypsin
      treatment. The label in glycolipids was quantitatively different in normal and
      transformed cells. The labeling pattern in glycoprotein and glycolipids of
      transformed NIL and 3T3 cells became similar to that of nontransformed cells when
      contact responses of transformed cells became conspicuous when cells were
      cultured in the presence of dextran sulfate or dibutyryl cyclic adenosine
      monophosphate, or in medium in which glucose was replaced with galactose.

PMID- 4357867
TI  - Specific photoaffinity labeling of the adenosine 3':5'-cyclic monophosphate
      receptor in intact ghosts from human erythrocytes.
AB  - [(3)H]N(6)-(Ethyl 2-diazomalonyl)-adenosine 3':5'-cyclic monophosphate is
      incorporated into intact ghosts from human erythrocytes on photolysis at 253.7
      nm. Incorporation is blocked in the presence of adenosine 3':5'-cyclic
      monophosphate (cyclic AMP) and does not occur in the absence of irradiation.
      Sodium dodecyl sulfate disc gel electrophoresis of solubilized ghosts shows that
      one protein is labeled. The position of this protein on the gel corresponds
      exactly to that previously found. [J. Biol. Chem. 247, 8145 (1972)] for the
      endogeneous protein substrate of the endogenous, cyclic AMP-dependent, protein
      kinase.

PMID- 4357868
TI  - Direct evidence of the C-like form of sodium deoxyribonucleate.
AB  - From infrared linear dichroism studies, direct evidence is given for a new Na DNA
      form, which is similar to the C form of Li DNA. This C-like form in Na DNA occurs
      under conditions of very low NaCl content (at high relative humidity), high NaCl
      content (at low relative humidity), and low G + C content of the DNA (at low
      relative humitiy). The C form of Li DNA was originally discovered by x-ray
      diffraction, but has not previously been characterized by infrared spectroscopy.
      The C form is primarily characterized by the orientation of the O2- -O3 line of
      the phosphate group, which is about 48 degrees (+/-2 degrees ) with respect to
      the helical DNA axis and which is different from that of the B and A forms. Na
      DNA molecules rich in A + T may entirely or partially adopt the C form at low
      relative humidity. Since from infrared evidence, the C-like form is found not
      only in Li DNA at low relative humidity but also in Na DNA under different
      conditions, the C form may be biologically important. A possible role for
      recognition by proteins is suggested.

PMID- 4357869
TI  - Inhibitory action of Ruthenium red on neuromuscular transmission.
AB  - The effect of Ruthenium Red on synaptic transmission was examined at isolated
      junctions of the frog, by conventional methods for stimulation and intracellular
      recording. Ruthenium Red (2.5-10.0 muM) reduces the synaptic potential to
      subthreshold levels. An analysis of this phenomenon shows that the main action of
      Ruthenium Red is on the presynaptic nerve terminal where it decreases the number
      of quanta of transmitter liberated by the nerve impulse. It has the following
      additional effects: a reduction in the amplitude of the spontaneous miniature end
      plate potentials; an increase in their frequency; and an increase in delayed
      release of transmitter after a nerve impulse. Some of these results are discussed
      in terms of the known inhibitory action of Ruthenium Red on calcium transport
      across mitochondrial membranes.

PMID- 4357870
TI  - Nuclear binding of steroid receptors: comparison in intact cells and cell-free
      systems.
AB  - In regulating gene expression in mammalian tissues, steroid hormones bind to
      cytoplasmic receptors and the resulting complex associates with the nucleus. In
      an attempt to study this nuclear association under more precisely controlled
      conditions, we examined the binding of receptor-[(3)H]steroid complexes to
      isolated nuclei. Two systems were used: the glucocorticoid-responsive hepatoma
      cell and the estrogen-sensitive immature rat uterus. Cell-free nuclear binding
      resembles that observed in the intact cell; it requires the receptor-steroid
      complex in the appropriate form ("active" complex); it is of high affinity; and
      it appears to involve about 4000 nuclear acceptor sites per haploid genome.
      Furthermore, whether binding occurs in intact cells or in cell-free extracts,
      complexes dissociate from nuclei at similar rates, and the ability of NaCl to
      extract either type of nuclear-bound complex and the sedimentation velocities of
      the extracted complexes are identical. Despite these similarities, acceptor sites
      detected in isolated nuclei differ from those of intact cells, since in neither
      hepatoma cells nor in the uterus do complexes bound to the nuclei of intact cells
      prevent further cell-free binding. We conclude that receptor-steroid complexes
      bind to acceptor sites in isolated nuclei that are chemically similar to, but
      topographically different from, those of the intact cell.

PMID- 4357871
TI  - Regulation of hepatic glycogen synthesis during fetal development: roles of
      hydrocortisone, insulin, and insulin receptors.
AB  - In fetal rat liver in utero, an increase in glycogen and the glycogen synthetic
      enzyme glycogen synthetase (EC 2.4.1.11) occurs between gestational days 17 and
      19. We used an organ culture system for finding the stimulus for increased enzyme
      activity and defining the relationship of this increase to glycogen synthesis. In
      fetal-liver explants from an earlier period (gestational day 16), hydrocortisone
      causes an elevation in total glycogen synthetase activity. This effect, which can
      be blocked by actinomycin D, is strikingly similar in time course and magnitude
      to the normal increase in utero. However, in order for glycogen synthesis to
      proceed after hydrocortisone increases glycogen synthetase levels, insulin is
      required. Unlike hydrocortisone, insulin does not increase total glycogen
      synthetase; it appears to act by converting the b or phospho form of synthetase
      to the a or dephospho form. Insulin alone does not stimulate glycogen synthesis
      in explants from 16-day fetal liver, although no defect in insulin binding was
      demonstrable. These findings support the hypothesis that the increase in liver
      glycogen synthesis during the last trimester requires glucocorticoids for the
      developmental induction of glycogen synthetase and insulin for activation of the
      enzyme.

PMID- 4357872
TI  - Thyroid hormone action in cell culture: domonstration of nuclear receptors in
      intact cells and isolated nuclei.
AB  - Triiodothyronine and thyroxine induce a 3-fold increase in the rate of growth of
      GH(1) cells in culture. To study further the action of these hormones, we
      examined the binding of [(125)I]triiodothyronine and purified [(125)I]thyroxine
      to cellular fractions after incubation with intact cells in serum-free medium.
      High-affinity, low-capacity binding sites for the hormones were demonstrated in
      nuclear but not in mitochondrial or cytosol fractions. Chromatographic analysis
      of the bound nuclear radioactivity from cells incubated with [(125)I]thyroxine
      demonstrated 97% thyroxine, 1% iodide, and 1% triiodothyronine. Apparent
      equilibrium dissociation constants, determined by Scatchard analysis, were 29 pM
      for triidothyronine and 260 pM for thyroxine. The maximal binding capacity was
      identical for both hormones, with about 5000 sites per cell nucleus.
      [(125)I]Thyroxine binding was competitively inhibited by triiodothyronine. These
      data suggest that triiodothyronine and thyroxine interact with identical nuclear
      receptors, and that conversion of thyroxine to triiodothyronine may not be a
      prerequisite for biologic activity. Similar high-affinity, low-capacity nuclear
      binding sites were also demonstrated by incubation of [(125)I]triidothyronine
      directly with isolated nuclei. Incubation of cells with increasing concentrations
      of nonradioactive triidothyronine results in a subsequent increase in binding
      when [(125)I]triiodothyronine is then incubated directly with isolated nuclei.
      This result suggests that nuclear receptors are not fixed, but increase after
      exposure of intact cells to hormone. This increase in nuclear receptor content
      may result from the transfer of an unstable cytosol receptor to the nucleus.

PMID- 4357873
TI  - Isolation of defective mutant of avian sarcoma virus.
AB  - A colony of transformed cells was isolated from chick-embryo cells infected with
      a stock of nondefective Schmidt-Ruppin strain of Rous sarcoma virus. The virus
      recovered from this colony was a stable defective mutant very similar to the
      Bryan strain of Rous sarcoma virus in the following characteristics: (i)
      noninfectiousness of virus particles released from transformed cells that lack
      helper factor; (ii) formation of infectious pseudotypes by coinfection with avian
      leukosis virus or by interaction with endogenous-helper factor in chicken cells;
      (iii) ability of the noninfectious form of virus to transform chick-embryo cells
      in the presence of ultraviolet light-inactivated Sendai virus; (iv) absence of
      glycoprotein in the noninfectious form; (v) failure to produce nondefective virus
      by recombination with avian leukosis virus; and (vi) segregation of polymerase
      negative virus. The morphology of transformed cells is characteristic of those
      infected by the Schmidt-Ruppin strain. The demonstration of segregation of such a
      defective virus from nondefective sarcoma virus and failure to detect revertants
      of this mutant suggest that the deletion of some genes may be involved in this
      mutation.

PMID- 4357874
TI  - Requirement of a phage-induced 5'-exonuclease for the expression of late genes of
      bacteriophage T5.
AB  - Amber mutants of bacteriophage T5 defective in gene D15, which codes for a 5'
      exonuclease, do not express late genes. Electrophoretic separation in sodium
      dodecyl sulfate-polyacrylamide gels of the proteins induced by this mutant in
      nonpermissive Escherichia coli show a virtual absence of late proteins. Synthesis
      of lysozyme and serum-blocking power is very low whereas the extent of synthesis
      of an early enzyme, deoxyribonucleoside monophosphokinase, is similar to that in
      wild-type infections. It is proposed that one requirement for the expression of
      late T5 genes is the introduction of gaps or nicks in the T5 DNA so that late
      transcription can occur.

PMID- 4357875
TI  - In vitro transcription of the viral-specific sequences present in the chromatin
      of cells transformed by simian virus 40.
AB  - Separated strands of simian virus 40 (SV40) DNA fragments were used in
      hybridization experiments to study the RNA transcribed by Escherichia coli RNA
      polymerase from the chromatin of cells transformed by SV40. The template activity
      of chromatin of the transformed cell line 11A8 (mouse-embryo cells) examined is
      about 17% that of purified DNA, suggesting that most of the chromatin DNA is
      repressed by chromosomal proteins. The SV40-specific RNA present in the RNA
      transcribed in vitro from 11A8 chromatin hybridizes specifically with the minus
      strand of SV40 DNA. Little or no reaction occurs with the plus strand of viral
      DNA. The SV40-specific RNA transcribed in vitro from chromatin of transformed
      cells shares sequences with the RNA produced during the early phase of SV40 lytic
      infection, and is similar to that present in the 11A8 cell line in vivo. Although
      the influence of chromosomal proteins on this pattern of transcription was not
      definitely determined, preliminary evidence indicates that an asymmetric pattern
      of transcription may also occur when 11A8 DNA is transcribed by E. coli RNA
      polymerase.

PMID- 4357876
TI  - Bone morphogenesis in implants of insoluble bone gelatin.
AB  - Insoluble bone gelatin with inclusions of insoluble noncollagenous protein
      produces new bone when implanted in muscle in allogeneic rats. The implanted
      residue provides the milieu for expression of bone morphogenetic potential of
      migratory mesenchymal cells. Neutral buffer solutions activate endogenous enzymes
      that degrade components essential for cell interactions and differentiation of
      bone. Chloroform-methanol either denatures or extracts constituents responsible
      for degradation. Insoluble bone gelatin produces new bone after extraction at 2
      degrees with neutral salts, 0.5 M EDTA, 0.1 M Tris.HCl, 4 M urea, 0.5 M
      hydroxylamine, and 10 M KCNS, as well as after limited digestion with pepsin or
      collagenase, but not after extraction with 5 M guanidine, 7 M urea, water
      saturated with phenol, or after alkali hydrolysis with 0.1 N NaOH. The specific
      activity of cell populations interacting with insoluble bone gelatin suggests
      that a chemical bond between collagen and a noncollagenous protein or part of a
      protein, cleaved by a neutral proteinase, controls the bone morphogenetic
      reaction.

PMID- 4357877
TI  - Regulation of nucleoside cyclic 3':5'-monophosphate phosphodiesterase activity
      from rat brain by a modulator and Ca2+.
AB  - Gel filtration of the 40,000 rpm supernatant fraction of a homogenate of rat
      cerebral cortex on a Sepharose 6B column yielded two fractions: fraction II with
      the "Ca(2+) plus Mg(2+)-dependent" phosphodiesterase activity and fraction III
      containing its modulator. The activity of fraction II was stimulated by
      micromolar concentrations of Ca(2+) and the modulator when present together; the
      modulator stimulated the activity of fraction II only when the Ca(2+)
      concentration was above a threshold value (about 2 muM with 0.4-1 muM substrate),
      and the stimulatory effect of Ca(2+) was dependent upon the presence of the
      modulator. A possibility is discussed that the modulator may reversibly bind to
      the enzyme, which by itself is inactive, to form an active enzyme-modulator
      complex and that Ca(2+) stimulates the activity of phosphodiesterase by shifting
      the equilibrium between these three species towards the formation of the active
      enzyme-modulator complex. Although fraction II hydrolyzed both cyclic AMP and
      cyclic GMP, hydrolysis of the latter was more significantly influenced by Ca(2+)
      and the modulator than that of the former, and the "Ca(2+) plus Mg(2+)-dependent"
      phosphodiesterase is likely to be a cyclic GMP enzyme. This conclusion is based
      on the following evidence: (a) Ca(2+) stimulated hydrolysis of cyclic GMP by
      fraction II more than that of cyclic AMP. (b) In the presence of Ca(2+) and the
      modulator, fraction II hydrolyzed cyclic GMP about 8 times faster than cyclic AMP
      when incubated with 0.4 muM substrate. (c) Half-maximal stimulation of hydrolysis
      of cyclic GMP was attained at a lower concentration of Ca(2+) (4 muM) than that
      of cAMP (8 muM). (d) Increase in the concentration of Ca(2+) from 0.06 muM to 12
      muM in the presence of the modulator caused a decrease in the K(m) value of
      cyclic GMP hydrolysis by fraction II from 20 muM to 2 muM accompanied by 4-fold
      increase in the V(max) value. Under similar conditions, there was only a slight
      decrease in the K(m) value of cylic AMP hydrolysis (90 muM --> 50 muM), although
      the V(max) value increased 7-fold. The anomalous shape of the kinetic plot of
      cyclic GMP hydrolysis became linear when the Ca(2+) concentration was increased
      in the presence of the modulator. The modulator seems to be a protein, but it is
      heat stable. It is probably identical to the protein activator of
      phosphodiesterase first described by Cheung.

PMID- 4357878
TI  - Cytochrome c: observation of numerous single-carbon sites of the reduced and
      oxidized species by means of natural-abundance 13C nuclear magnetic resonance
      spectroscopy.
AB  - Proton-decoupled, natural-abundance (13)C nuclear magnetic resonance spectra
      (obtained at 15.18 MHz by the Fourier transform method) of aqueous
      ferrocytochrome c, ferricytochrome c, and mixtures of both species were recorded.
      The 18 nonprotonated aromatic carbons of amino-acid residues and the 16
      nonprotonated aromatic carbons of the heme yielded 22 narrow single-carbon
      resonances and 6 narrow two-carbon resonances in the spectrum of ferrocytochrome
      c. Only some of these resonances were detected in the spectrum of ferricytochrome
      c. Fast electron transfer between ferrocytochrome c and ferricytochrome c
      produced chemical exchange effects in spectra of mixtures of the two species: 16
      nonprotonated aromatic carbons yielded narrow exchange-averaged resonances as a
      consequence of their small natural linewidths in both redox states and the small
      changes in their chemical shifts (relative to the reciprocal of the lifetime
      between electron exchange) when going from the reduced to the oxidized species.
      These peaks were assigned to carbons situated far from the iron atom. Their fast
      exchange behavior was used to establish a one-to-one correspondence between
      resonances in spectra of the two redox states. The other 18 nonprotonated
      aromatic carbons yielded exchange-broadened resonances as a consequence of large
      chemical-shift differences between the diamagnetic and paramagnetic species,
      and/or large paramagnetic broadening of the resonances of ferricytochrome c. We
      assigned these resonances (only one of which was identified in the spectrum of
      ferricytochrome c alone) to carbons that are near the iron atom: C(zeta) of Tyr
      67, C(gamma) of His 18, and the 16 nonprotonated carbons of the porphyrin ring.
      Tentative specific assignments for C(zeta) of Tyr 67 (in the spectra of both
      redox forms) and for C(zeta) of His 18 (in the spectrum of ferrocytochrome c) are
      also presented.

PMID- 4357879
TI  - Ribonucleic acid components of murine sarcoma and leukemia viruses.
AB  - Defective Kirsten murine sarcoma virus was present as leukemia virus pseudotype
      [Ki-MSV(MLV)] in a 10- to 100-fold excess over its helper, Kirsten murine
      leukemia virus (Ki-MLV), when the two viruses were propagated in an NRK rat cell
      line. The s(omega,20) of the fastsedimenting RNA complex of Ki-MLV and of Ki-MSV
      (MLV) was 62 S and 55 S, respectively. Gel electrophoresis in buffered aqueous or
      formamide solution of the dissociated 62S RNA complex of Ki-MLV showed a single
      major peak of molecular weight about 2.5 x 10(6). Dissociated 55S RNA of Ki
      MSV(MLV) was resolved into a major component with a higher electrophoretic
      mobility than that of Ki-MLV RNA and molecular weight about 2.3 x 10(6).
      Occasionally, a minor component with the same electrophoretic mobility as Ki-MLV
      RNA was observed in Ki-MSV(MLV) RNA; it is thought to be the RNA of Ki-MLV
      present as helper virus in our stocks of Ki-MSV(MLV). The RNA of an endogenous
      rat C-type RNA virus was electrophoretically different from both Ki-MLV RNA and
      Ki-MSV(MLV) RNAs. Oligonucleotide fingerprinting of the RNAs digested with RNase
      T1 indicated that the RNAs of Ki-MSV(MLV) and Ki-MLV are different. However, the
      extent of the difference between the two RNAs could not be estimated by this
      method. The heat-dissociated 50-70S RNAs of two other defective murine sarcoma
      leukemia viruses; Harvey-MSV(MLV) and Moloney-MSV(MLV) and of defective spleen
      focus-forming Friend virus were resolved electrophoretically into two components.
      The larger components had the same electrophoretic mobility as the RNA of Ki-MLV
      or Moloney MLV. The smaller were not present in leukemia virus. It is suggested
      that the small RNA components of the two murine viruses and of Friend virus
      represent specific genetic information of these replication-defective
      transforming viruses. Possible relationships between the RNAs of murine leukemia
      viruses and replication-defective murine sarcoma and Friend viruses are
      discussed.

PMID- 4357880
TI  - In vitro synthesis of RNA that contains polyadenylate by virion-associated RNA
      polymerase of vesicular stomatitis virus.
AB  - The RNA synthesized in vitro by the virion-associated RNA-instructed RNA
      polymerase of purified vesicular stomatitis virus contains polyadenylate
      sequences. These have been demonstrated by their partial resistance to pancreatic
      and T(1) ribonucleases and their capacity to bind to poly(U) filters and
      oligo(dT)-cellulose. The polyadenylate sequences range in apparent size from 50
      to 200 bases, similar to the size of the poly(A) in mRNA from vesicular
      stomatitis virus-infected cells. Possible mechanisms of polyadenylylation of the
      in vitro RNA product are discussed.

PMID- 4357881
TI  - Electron transport-linked compared with proton-induced ATP generation in
      Thiobacillus novellus.
AB  - The apparently soluble electron-transport system, that does not sediment when
      centrifuged at 144,000 x g or 300,000 x g for 3 hr, catalyzes oxidative
      phosphorylation with an efficiency comparable to that of an intact mitochondrial
      system. While the proton-induced phosphorylation occurs in whole cells, crude
      cell-free extracts, and supernatants from low-speed centrifugation, it does not
      occur in either the 144,000 or 300,000 x g supernatant fractions. The data show
      that oxidative energy can be conserved as ATP under conditions that are
      incompatible with the basic postulate of the chemiosmotic hypothesis.

PMID- 4357882
TI  - Role of cyclic 3':5'-adenosine monophosphate in the early transport changes
      induced by serum and insulin in quiescent fibroblasts.
AB  - Serum or insulin added to quiescent mouse-embryo fibroblasts produced rapid
      increases in the rate of transport of uridine and phosphate and a decrease of the
      intracellular concentration of cyclic AMP. Incubation of the cells with
      prostaglandin E(1), theophylline, or both prevented the increase in uridine
      transport produced by serum or insulin. Prostaglandin E(1) was more effective
      than prostaglandins E(2) and B(1). Kinetic experiments showed that the addition
      of prostaglandin E(1) and theophylline causes the uridine transport rate to
      return to the basal level within 5 min; the rate rose rapidly after their
      removal. Similar effects were obtained when insulin was used instead of serum.
      Associated with these transport changes were significant variations in the levels
      of cyclic AMP. An inverse correlation between the changes in uridine transport
      and those in cyclic AMP concentration was shown under various experimental
      conditions. In contrast to the effects observed with uridine transport, phosphate
      uptake was only slightly affected by changes in the endogenous level of cyclic
      AMP. We propose that at least two different sorts of membrane changes are rapidly
      initiated by serum, one under cyclic AMP control and the other not related to
      this nucleotide.

PMID- 4357883
TI  - Assignment of the T-antigen gene of simian virus 40 to human chromosome C-7.
AB  - Hybrid cell clones between mouse cells deficient in thymidine kinase (EC
      2.7.1.21) and two different human cell lines transformed by simian virus 40
      (SV40) and deficient in hypoxanthine phosphoribosyltransferase (EC 2.4.2.8) were
      examined for SV40 tumor (T) antigen(s). Concordant segregation of the gene(s) for
      SV40 T antigen and human chromosome C-7 was observed in these hybrids. The human
      chromosome C-7 which contains the gene(s) for SV40 T antigen is preferentially
      retained by the majority of the hybrid clones tested. When hybrid clones positive
      and negative for SV40 T antigen, derived from the fusion of SV40-transformed
      Lesch-Nyhan fibroblasts with mouse cells, were fused with CV-1 permissive cells,
      SV40-specific V antigen was observed only in the cultures derived from fusion of
      the hybrid clones positive for T antigen. This result indicates a linkage
      relationship between human chromosome C-7, SV40 T-antigen gene(s), and SV40
      genome(s) integrated in the human transformed cells.

PMID- 4357885
TI  - Changes in membrane structure associated with cell contact.
AB  - Ultrastructural analysis of 3T3 fibroblasts by freeze-cleavage has demonstrated
      significant changes in cell-membrane structure associated with cell-to-cell
      contact and malignant transformation. These changes consist of a rearrangement
      and redistribution of intramembranous particles on the membrane fracture faces
      exposed by freeze-cleavage. The results show that noncontacted 3T3 cells in low
      density contain randomly distributed intramembranous particles. With the
      development of cell-to-cell contacts during the logarithmic phase of growth
      however, a pronounced aggregation of intramembranous particles is seen. A direct
      correlation between the degree of cell contact and the percentage of cells
      showing intramembranous-particle aggregation has been established. By contrast,
      transformed SV3T3 and SP3T3 cells show no evidence of intramembranous-particle
      aggregation even at cell densities where cell-to-cell contact is extensive. In
      view of recent reports that intramembranous particles represent foci of
      interaction between certain intrinsic membrane proteins and lipids, we propose
      that cell-to-cell contact of nontransformed 3T3 cells may initiate a change in
      the distribution of intrinsic membrane proteins associated with intramembranous
      particles and that these changes may influence control of cell proliferation.

PMID- 4357884
TI  - Infectious DNA from herpes simplex virus: infectivity of double-stranded and
      single-stranded molecules.
AB  - The infectious units in native and alkalidenatured preparations of DNA of herpes
      simplex virus were characterized with respect to their sensitivity to Neurospora
      crassa endonuclease, their sedimentation properties in high-salt, neutral sucrose
      gradients, and their sensitivity to hydrodynamic shearing forces. Infectious
      molecules in native preparations were resistant to N. crassa endonuclease,
      sedimented at 56 S, and were highly sensitive to shearing forces. After alkaline
      denaturation, infectious molecules became sensitive to the N. crassa enzyme,
      sedimented at 200 S, and were relatively resistant to shear. We conclude that
      both intact duplex molecules ([unk]100 x 10(6) daltons) and intact single strands
      ([unk]50 x 10(6) daltons) are capable of initiating productive infection.

PMID- 4357886
TI  - Changes in rabbit-liver lysosomes and fructose 1,6-bisphosphatase induced by cold
      and fasting.
AB  - Exposure of rabbits to cold or fasting results in marked increases in the number
      and size of liver lysosomes, associated with increases in the total and "free"
      proteolytic activity. Changes in lysosomal morphology also indicate increased
      activity and fragility. These effects of cold and fasting are correlated with
      decreases in the levels of liver fructose bisphosphatase (EC 3.1.3.11) activity
      and changes in the molecular properties of the purified enzyme, including the
      loss of a small peptide containing the only tryptophan residue in the peptide
      chain.

PMID- 4357887
TI  - In vivo inhibition of growth of two hormone-dependent mammary tumors by dibutyryl
      cyclic AMP.
AB  - Growth of hormone-dependent rat mammary tumors was arrested in vivo by N(6),O(2)'
      dibutyryl cyclic adenosine 3',5'-monophosphate. Estrogen concentration did not
      change, but acid ribonuclease activity and synthesis increased during treatment
      with the dibutyryl cyclic nucleotide, as was shown during tumor regression due to
      hormonal deprivation. Growth arrest, thus, appears to derive from enhanced tissue
      catabolism.

PMID- 4357888
TI  - [History of the earth and biochemical evolution].

PMID- 4357889
TI  - Water-soluble contrast media and adhesive arachnoiditis. I. Reinvestigation of
      nonoperated cases.

PMID- 4357890
TI  - Late sequelae following lumbar myelography with water-soluble contrast media.

PMID- 4357891
TI  - Streptozotocin diabetes--further studies on the mechanism of depression of
      nicotinamide adenine dinucleotide concentrations in mouse pancreatic islets and
      liver.

PMID- 4357892
TI  - Effects of some isoquinoline compounds and certain derivatives on brain
      phosphodiesterase activity.

PMID- 4357893
TI  - Biliary excretion of nicotinamide riboside. A possible role in the regulation of
      hepatic pyridine nucleotide dynamics.

PMID- 4357894
TI  - Aryl hydrocarbon hydroxylase induction in mammalian liver cell culture. IV.
      Stimulation of the enzyme activity in established cell lines derived from rat or
      mouse hepatoma and from normal rat liver.

PMID- 4357895
TI  - Neural activity in the dorsal hippocampus during paradoxical sleep, slow wave
      sleep and waking.

PMID- 4357897
TI  - Glial uptake of taurine in the rabbit retina.

PMID- 4357896
TI  - Evidence against cyclic adenosine 3',5'-monophosphate (AMP) mediation of
      noradrenaline depression of cerebral cortical neurones.

PMID- 4357898
TI  - Talc injury: changes in glucosamine and leucine incorporation into liver and
      plasma proteins.

PMID- 4357899
TI  - Familial hyperlipoproteinemia and thyroid dysfunction of beagles.

PMID- 4357900
TI  - [Progestogen receptor in the uterus of rabbits and rats].

PMID- 4357901
TI  - Influences on the structural stability of collagen in relation to ageing.

PMID- 4357902
TI  - Effect of 25-hydroxycholecalciferol (25-HCC) on intestinal absorption of 47Ca in
      four cases of iatrogenic Cushing's syndrome.

PMID- 4357903
TI  - Increased plasma renin substrate concentration in human malignant hypertension.

PMID- 4357905
TI  - [Investigation of poliovirus neutralizing antibody level in nurse students].

PMID- 4357904
TI  - Serum lipids, dietary intakes, and physical exercise in medical students.

PMID- 4357906
TI  - Depth-electroencephalograms of chickens in wakefulness and sleep.

PMID- 4357907
TI  - [Dermatoplasty].

PMID- 4357908
TI  - Letter: The stability of Clostridium perfringans type D epsilon toxin in
      intestinal contents in vitro.

PMID- 4357909
TI  - Terminal dentistry and the management of the atrophied mandible.

PMID- 4357910
TI  - A genetic study of syndactyly in Utah.

PMID- 4357911
TI  - [Effect of benz-alpha-anthracene on the interaction of 7,12-dimethylbenz-alpha
      anthracene with cultures of normal and malignant hamster cells].

PMID- 4357912
TI  - [Localization of polymeric iron orthophosphate in Penicillium chrysogenum].

PMID- 4357913
TI  - Alkaline phosphatase levels in canine mammary neoplasia.

PMID- 4357914
TI  - [Rubomycin in the treatment of trophoblastic tumors].

PMID- 4357915
TI  - [Sensitivity of the Dzungarian hamster to the Rous virus and simian virus 40].

PMID- 4357916
TI  - [Fractional composition of cell proteins in Zajdela ascites hepatoma and rat
      liver].

PMID- 4357917
TI  - [Recurrent tumors of the soft tissues].

PMID- 4357919
TI  - [Carcinoma of the right side of the colon].

PMID- 4357918
TI  - [Relation of survival of patients with breast neoplasms to morphological
      differentiation of the tumor and exclusion of ovarian function].

PMID- 4357920
TI  - [Coexistence of leiomyomata and chemodectomata in the stomach].

PMID- 4357921
TI  - [Average degeneracy of coding of cytochromes].

PMID- 4357922
TI  - Chemical oncogenesis in culture.

PMID- 4357924
TI  - [Principles of electron spin resonance as applied to biological studies on
      spermatozoa or other free-moving cells].

PMID- 4357923
TI  - Isozymes and cancer.

PMID- 4357925
TI  - [Electron spin resonance studies on sedimented spermatozoa].

PMID- 4357926
TI  - [Histochemical studies on the kidney of the domestic duck (Anas boschus domestica
      L.)].

PMID- 4357928
TI  - [Influence of prolonged artificial circulation on the metabolism of the dog's
      heart].

PMID- 4357927
TI  - [Treatment of primary hyperlipoproteinaemia types, IIa, IIb, 3 and IV with
      clofibrate (author's transl)].

PMID- 4357929
TI  - Effect of 5-iodo-2-deoxyuridine, cycloheximide and rivanol on the multiplication
      of vaccinia and fowlpox viruses in chick embryo fibroblast culture.

PMID- 4357930
TI  - Bordetella pertussis infection in Chandigarh.

PMID- 4357931
TI  - Variants of vibrio cholerae in Delhi.

PMID- 4357932
TI  - Vitamin D and rickets.

PMID- 4357933
TI  - Inhibitory and restorative effects of adenine nucleotides on rickettsial
      adsorption and hemolysis.
AB  - The adenine nucleotides, adenosine diphosphate, adenosine triphosphate, (ATP),
      and the methylene-bridge analogues are inhibitors of rickettsial adsorption to
      and the hemolysis of sheep erythrocytes. Other nucleotides, adenosine
      monophosphate, cyclic adenosine monophosphate, cytosine triphosphate, and
      guanosine triphosphate, are without effect. Adsorption and hemolysis require the
      generation of energy by the rickettsiae which is usually derived from glutamate.
      When the generation of energy from the metabolism of glutamate is inhibited by
      arsenite or cyanide, the addition of ATP can supply the energy to restore
      hemolysis. However, in the presence of the uncouplers, ATP can not restore
      hemolysis. Even when functioning in a restorative role, ATP still has its
      inhibitory properties. These results suggest that a high-energy intermediate (X
      approximately I), rather than ATP itself, is the energy source. The interactions
      of inhibitory nucleotides suggest that these compounds share a common transport
      system.

PMID- 4357934
TI  - Isolation of Clostridium absonum and its cultural and biochemical properties.
AB  - A new procedure for isolation of Clostridium absonum was devised. Sixtyseven
      strains of C. absonum were isolated from 135 soil samples, but no strain of C.
      absonum could be found from human fecal samples. The lecithinase, hemolysin, and
      lethal toxin in the culture filtrates of this species exhibited low avidity for
      C. perfringens type A antitoxin. The three activities were inseparable by the
      present method of purification. A reinvestigation of biochemical properties
      revealed that incomplete suppression of lecithinase reaction by C. perfringens
      type A antitoxin and no fermentation of raffinose, melibiose, and starch are
      useful criteria to differentiate C. absonum from C. perfringens, and that
      positive, although weak, gelatin liquefaction and fermentation of trehalose are
      useful to differentiate it from C. paraperfringens.

PMID- 4357935
TI  - N-terminal aspartate, glycine and serine in poliovirus capsid protein.

PMID- 4357936
TI  - The synthesis and substructure of herpesvirus DNA: the distribution of alkali
      labile single strand interruptions in HSV-1 DNA.

PMID- 4357937
TI  - Fusion of a Rous sarcoma virus transformed human cell line, KC, by RD-114 virus.

PMID- 4357938
TI  - Studies on the histamine sensitisation produced in mice by Corynebacterium
      parvum.

PMID- 4357939
TI  - Some effects of preganglionic nerve stimulation on synaptic vesicle populations
      in the rat superior cervical ganglion.
AB  - 1. The ;local vesicle population', namely the population of synaptic vesicles
      lying within a zone 0.25 mum wide adjacent to the presynaptic membrane and
      expressed as ;vesicles mum(-2)' has been estimated in rat superior cervical
      ganglia maintained in vitro for 1 h. Ganglia were either unstimulated or
      stimulated tetanically during the last few minutes of the in vitro period.2.
      Individual local vesicle populations at synapses in groups of ganglia which had
      received the same treatment showed an approximately normal frequency
      distribution.3. The technique of stimulation did not permit fixation during
      tetanus, but the mean local vesicle population in ganglia fixed a few seconds
      after 10 Hz tetani of up to 10 min duration were significantly (P < 0.001) higher
      than the unstimulated control value of 124.0 +/- S.E. 3.2. Ganglia fixed a few
      seconds after 3 min tetani at 10 Hz had a mean local vesicle population of 155.7
      +/- S.E. 5.7, rising slightly but not significantly to 165.0 +/- S.E. 4.3 at 1
      min and 163.1 +/- S.E. 5.2 at 2 min after tetanus. Thereafter the mean local
      vesicle population fell slowly, reaching control level between 10 and 20 min
      after tetanus.4. In terms of the vesicle hypothesis, the observations suggest
      that post-tetanic potentiation might arise from a closer clustering of vesicles
      about release areas resulting in an increase in fractional release. It is
      suggested that stimulation increased the local vesicle population by promoting
      vesicle mobilization rather than by altering the size or shape of the presynaptic
      terminals. The ;mobilizing agent' might be intracellular Ca(2+).5. The results
      appear to be consistent with those of other workers where experimental conditions
      and the region in which vesicles were counted were comparable.6. Alternative
      interpretations for the findings, not involving the vesicle hypothesis, are
      considered.

PMID- 4357940
TI  - Activation of descending control of the spinocervical tract by impulses ascending
      the dorsal columns and relaying through the dorsal column nuclei.
AB  - 1. Micro-electrode recordings were made from axons of the spinocervical tract in
      unanaesthetized decerebrate cats.2. Orthodromic activation of the dorsal columns
      and dorsal column nuclei was used to condition responses evoked in spinocervical
      tract neurones from cutaneous nerves. Such conditioning produced inhibition of
      transmission through the tract. The inhibition had a time course of 200 msec or
      more with maximal action at 30-70 msec and was most effective against
      polysynaptic responses.3. After removal of the cerebellum or section of the
      cerebellar peduncles the degree of inhibition was reduced but inhibition could
      still be evoked by activation of the dorsal columns and dorsal column nuclei.4.
      Transection of the brain stem just rostral to the dorsal column nuclei removed
      the inhibitory effects although segmental inhibition was not affected.5. It is
      concluded that impulses ascending the dorsal columns and relaying through the
      dorsal column nuclei can lead to activation of descending control of the
      spinocervical tract. Parts of the pathways involved include the cerebellum and
      the brain stem. It is unlikely that the cells in the dorsal column nuclei which
      have descending axons are concerned with the control of transmission through the
      spinocervical tract.

PMID- 4357941
TI  - [Studies of lymphoblastoid cell lines derived from Down's syndrome. 1.
      Establishment of lymphoblastoid cell lines and their characteristics (author's
      transl)].

PMID- 4357942
TI  - [Cytostatic therapy of bronchial carcinoma].

PMID- 4357943
TI  - [Effects of pesticides: Nogos G50, MCPA-500 and Pol-Kupritox-50 on cytochrome
      oxidase (E.C.1.9.3.1.)].

PMID- 4357944
TI  - [Oncogenicity of avian sarcoma viruses (author's transl)].

PMID- 4357945
TI  - Thymus adenylate cyclase activity during murine leukemogenesis.
AB  - Activity of thymus adenylate cyclase was more than three times higher in leukemic
      AKR mice than in nonleukemic AKR mice and CBA mice. Preleukemic AKR mice that had
      no evidence of leukemia but were expected to soon develop the disease exhibited
      similarly elevated activities of thymus adenylate cyclase.

PMID- 4357946
TI  - Negative inotropic effect of cyclic AMP on the isolated canine heart muscle.

PMID- 4357947
TI  - The cricopharyngeus muscle. An electrophysiological and neuropharmacological
      study.

PMID- 4357949
TI  - [Role of pH in biosynthesis of florimycin].

PMID- 4357948
TI  - Unit activity of ganglionic and medullary second order neurones in the eel
      lateral line system.

PMID- 4357950
TI  - [Experimental studies on the antiviral effect of distamycin A].

PMID- 4357951
TI  - [Pharmacological study of human leukocytic interferon].

PMID- 4357952
TI  - [Method for determination of penicillinamidase activity].

PMID- 4357953
TI  - Effect of feeding protected lipid on the uptake of precursors of milk fat by the
      bovine mammary gland.

PMID- 4357954
TI  - Tumor producing capacity of temperature sensitive mutants of avian sarcoma
      viruses in chicks.

PMID- 4357955
TI  - Studies by electron paramagnetic resonance on the catalytic mechanism of
      nitrogenase of Klebsiella pneumoniae.
AB  - The properties and catalytic reactions of the enzyme nitrogenase purified from
      Klebsiella pneumoniae were studied by electron-paramagnetic-resonance (e.p.r.)
      spectroscopy at temperatures down to 8 degrees K. The two protein fractions, Kp1
      (the iron-molybdenum protein) and Kp2 (the iron protein), were examined alone and
      in steady-state mixtures and also in pre-steady-state experiments, by using the
      rapid-freezing method. Kp1 protein in dithionite solution shows a rhombic type of
      spectrum with g(1) 4.32, g(2) 3.63, g(3) 2.009 at pH6.8 (0 degrees C). Small
      changes in the spectrum produced by protons (pK=8.7 at 0 degrees C) or by
      acetylene indicate binding of these oxidizing substrates to this protein
      fraction. Kp2 protein shows a rhombic spectrum with g(1) 2.053, g(2) 1.942, g(3)
      1.865, which integrates to about 0.45 electron/molecule. Binding of ATP, with a
      dissociation constant of 4x10(-4)m, changes the spectrum to an axial form with g(
      parallel) 2.036, g( perpendicular) 1.929, thus indicating a conformation change
      of Kp2 protein. The Kp2 protein spectrum disappears reversibly on cautious
      oxidation. The signals of both proteins are diminished in their steady-state
      mixtures, obtained in the presence of ATP and dithionite (with an ATP-generating
      system and Mg(2+) ions) and with protons, N(2) or acetylene as oxidizing
      substrate. At the same time as dithionite is consumed in such reactions, the Kp1
      protein signal is gradually restored and the Kp2 protein signal diminishes to
      zero. In rapid-freezing experiments the signals from the two proteins decreased
      at indistinguishable rates (t((1/2)) about 10ms), then they remained constant.
      Results are interpreted in terms of a scheme in which reducing equivalents pass
      from dithionite to Kp2 protein, then, in an ATP-dependent reaction to Kp1
      protein, this being finally reoxidized by N(2) or another oxidizing substrate. In
      this scheme Kp1 protein cycles between its signal-giving state and a very highly
      reduced signal-free state.

PMID- 4357956
TI  - Superoxide dismutase: a contaminant of bovine catalase.
AB  - Some commercial samples of bovine catalase contain superoxide dismutase activity.
      Therefore the inhibition of a reaction on the addition of a catalase preparation
      need not necessarily mean that H(2)O(2) is responsible for the reaction.

PMID- 4357958
TI  - Mental health: systems and non-systems.

PMID- 4357957
TI  - Electrical changes in the membrane in junctional transmission.

PMID- 4357959
TI  - On the pharmacology of ascending, decending and recurrent postsynaptic inhibition
      of the cuneo-thalamic relay cells in the cat.
AB  - 1. In cats decerebrated or anaesthetized with pentobarbitone, cells of the middle
      third of the cuneate nucleus that were excited by tactile stimulation of the
      ipsilateral forelimb (responding to displacement of hairs, skin or joints) and
      inhibited by electrical stimulation of the contralateral pyramid, were invariably
      inhibited by electrical stimulation of the ipsilateral forepaw and the
      contralateral forelimb nerves.2. In 50% of the cats, the cells were more fully
      identified by placing electrodes stereotaxically in the contralateral medial
      lemniscus. Recurrent inhibition was always a concomitant of the antidromic action
      potential.3. The intensity and the duration of inhibition evoked by all of these
      pathways was totally resistant to iontophoretic and intravenous strychnine in
      doses at least 5 times that required to block completely the response of the same
      cells to iontophoretic glycine and was extremely sensitive to either
      iontophoretic bicuculline or picrotoxin.4. Although the inhibition was invariably
      sensitive to intravenous picrotoxin, no significant change occurred in the
      duration or intensity of the inhibition when bicuculline was administered
      intravenously (5 or 6 times) as repeated doses of 0.2 mg/kg.5. Postsynaptic
      inhibition in the cuneate may be mediated by gamma-aminobutyric acid released
      from the nerve terminals of a common pool of interneurones shared by ascending,
      descending and recurrent pathways. Since the receptors involved in this pathway
      are resistant to intravenous bicuculline, they may well be distinct from those
      responsible for changes in the primary afferent terminal excitability, usually
      believed to be associated with presynaptic inhibition.

PMID- 4357960
TI  - The action of bombesin on the kidney of the anaesthetized dog.
AB  - 1. In the anaesthetized dog bombesin had a potent antidiuretic effect, and
      sometimes arrested urine flow completely. Threshold doses, by i.v. infusion, were
      of the order of 0.5-1 (ng/kg)/minute. Antidiuresis was the result of a reduction
      in glomerular filtration rate provoked by a fall in intraglomerular hydrostatic
      pressure. This, in its turn, was due to afferent vasoconstriction.2. The
      spasmogenic effect of bombesin on the smooth muscle of the afferent arterioles
      was directly demonstrated by the radioactive microspheres technique and
      indirectly by the (85)Kr washout method and by [(3)H]-p-aminohippurate clearance.
      The vascular compartment most sensitive to bombesin was that of the outer
      cortical zone, especially in its external half.3. Filtration fraction decreased
      under the influence of bombesin, indicating that the effect of the polypeptide on
      postglomerular arterioles was, if present, only of minor importance.4. At high
      infusion rates (above 6 (ng/kg)/min), bombesin produced a decrease in [(3)H]-p
      aminohippurate extraction. The effect of the polypeptide on fractional distal
      delivery of sodium varied with the dose: at moderate infusion rates it decreased,
      at high infusion rates it increased. The total glucose appearing in urine
      following a glucose load was sharply reduced by bombesin. However, the glomerular
      filtration rate/maximum tubular glucose transport ratio did not show any
      appreciable change.5. Afferent vasoconstriction produced by bombesin was
      accompanied by an intense activation of the renin-angiotensin system, as shown by
      a conspicuous increase in renin secretion, followed by increases in renin
      activity and angiotensin II concentration in arterial blood. When bombesin was
      infused into one renal artery only the infused kidney showed afferent
      vasoconstriction and increased renin secretion. The time-course of renin
      secretion produced by bombesin depended upon the rate of infusion of the
      polypeptide. At low rates an increased renin secretion was observed throughout
      the infusion period, at high rates two peaks of renin secretion could be seen,
      one at the beginning of the infusion, the other soon after the infusion had
      finished.6. The mechanism of action of bombesin is discussed and the interest of
      the polypeptide as a possible hormonal regulator of the circulation and function
      of the kidney is pointed out.

PMID- 4357961
TI  - Fate of angiotension I in the total Bufo melanostictus.
AB  - 1. The effects of angiotensin I and II on the blood pressure of pithed toads and
      the disappearance of angiotensin I and II in the perfused organs of the toad were
      studied.2. Angiotensin I was relatively inactive on the blood pressure of pithed
      toads; it exhibited less than 3% of the pressor activity of angiotensin II.3.
      Angiotensin I was not converted to angiotensin II during passage through the
      lungs. There was also no evidence of net conversion during passage through the
      kidney and hind quarters.4. During passage through the lungs, 33-50% of
      angiotensin I was removed and 25-50% was removed during passage through the hind
      quarters. No loss of activity was detected when angiotensin II passed through the
      kidneys.5. Angiotensin II passed through the lungs and kidneys without loss but
      25-50% disappeared during passage through the hind quarters.6. The relatively low
      pressor activity of angiotensin I together with its lack of conversion to
      angiotensin II in isolated perfused organs suggest that the converting enzyme is
      absent in the toad, Bufo melanostictus.

PMID- 4357962
TI  - Effect of anti-inflammatory drugs on the binding of calcium to cellular membranes
      in various human and guinea-pig tissues.
AB  - 1. Cellular membranes were obtained by centrifugation of homogenates of various
      human and guinea-pig tissues. These membranes took up added calcium (Ca) when
      incubated at 25 degrees C for 10 min in histidine buffer at pH 7.4. The uptake of
      Ca was increased by the presence of adenosine triphosphate (ATP).2. Evidence is
      presented that the membrane fragments which took up Ca under these conditions
      were derived from the endoplasmic reticulum.3. The ATP-dependent uptake of Ca by
      membranes derived from guinea-pig aortic or gastric smooth muscle or from human
      umbilical arterial muscle was inhibited by indomethacin in a concentration
      dependent manner.4. The ATP-dependent uptake of Ca by membranes derived from
      heart, brain, skeletal muscle or liver of the guinea-pig was not inhibited by
      indomethacin.5. Endothelial cells were obtained from the lining of the human
      umbilical vein. Cellular membranes were prepared from the endothelial cells by
      homogenization and centrifugation. The endothelial membranes took up added Ca in
      the presence of added ATP and this uptake was inhibited by indomethacin and also
      by members of a group of pharmacologically-related drugs.

PMID- 4357963
TI  - The relation of adenyl cyclase to the activity of other ATP utilizing enzymes and
      phosphodiesterase in preparations of rat brain; mechanism of stimulation of
      cyclic AMP accumulation by NaF.
AB  - 1. A method for measuring the rate of production of (14)C-labelled adenine
      nucleotides, including cyclic adenosine 3',5'monophosphate (cyclic AMP), from
      [(14)C]-adenosinetriphosphate (ATP) was developed and used to study the effects
      of ATP, adenosine diphosphate (ADP) and adenosine 5'-monophosphate (AMP) on the
      rate of accumulation of cyclic AMP in cell-free preparations of adenyl cyclase
      from rat brain.2. The mechanism by which NaF increases cyclic AMP accumulation
      was studied by comparing its effect on adenine nucleotide metabolism with that of
      an ATP regenerating system.3. ADP and ATP are potent inhibitors of
      phosphodiesterase (PDE) and it is the sum of the concentrations of these two
      nucleotides which controlled the rate of destruction of cyclic AMP. The effect of
      these nucleotides was significant even in the presence of 6.7 mM theophylline;
      theophylline itself inhibited PDE only 50-60%.4. Fluoride ion had no direct
      effect on PDE but it inhibited the rate of hydrolysis of ADP and ATP and thus
      indirectly inhibited PDE. The effect of fluoride ion on cyclic AMP accumulation
      can be explained, at least in part, by this indirect inhibition of PDE.5. Studies
      on a more purified preparation of adenyl cyclase clearly demonstrated a direct
      action of NaF on adenyl cyclase.

PMID- 4357964
TI  - Effect of a sulphated glycopeptide on rat gastric acid secretion stimulated by
      histamine, bethanechol, pentagastrin and dibutyryl cyclic AMP.
AB  - The antisecretory activity of a semisynthetic sulphated glycopeptide (GLPS) was
      studied in rats in which the secretion rates of gastric acid were detennined on
      the perfused stomach preparation. GLPS at 1 mg/kg i.v. reduced the hypersecretory
      effect of dibutyryl cyclic AMP, histamine, pentagastrin, bethanechol but not of
      theophylline.

PMID- 4357965
TI  - The action of two inhibitors of glutamic acid uptake upon amino acid-induced and
      synaptic excitations of thalamic neurones.

PMID- 4357966
TI  - Modifications of the firing rate of bulbar reticular units (nucleus
      gigantocellularis) after intra-arterial injection of bradykinin into the limbs.

PMID- 4357967
TI  - The action of piperidine on cholinoceptive neurons of the snail.

PMID- 4357968
TI  - Electrophysiology of the frontal granular cortex. II. Patterns of spontaneous
      discharges of impulses of neurons in the cortex through states of sleep and
      wakefulness in the monkey.

PMID- 4357969
TI  - Altered distribution of choline acetyltransferase and acetylcholinesterase
      activities in the developing rat dentate gyrus following entorhinal lesion.

PMID- 4357970
TI  - Effect of psychotropic drugs on phosphodiesterase and cyclic AMP level in rat
      brain in vivo.

PMID- 4357971
TI  - The efflux of 45CA2+ and (3H)gamma-aminobutyric acid from cate cerebral cortex.

PMID- 4357972
TI  - The neuronal pathway subserving the pupillary light reflex and its facilitation
      from cerebellar nuclei.

PMID- 4357973
TI  - Studies on post-tetanic depression of the dorsal root reflex in the forelimb skin
      nerves of the cat.

PMID- 4357974
TI  - Burst formation in electrically coupled neurons.

PMID- 4357975
TI  - WHO collaborative studies on enterovirus reference antisera; fourth report.
AB  - This paper summarizes the results of the fourth part of a comprehensive programme
      undertaken by the WHO International Reference Centre for Enteroviruses and other
      laboratories for the testing of enterovirus equine antisera prepared for long
      term use as reference antisera. The studies were designed to appraise the
      specificity of the immune serum of horses inoculated with prototype enteroviruses
      (coxsackievirus types A2, 4, 8, 10, 11, 14-16, 18-21, and 24, and echoviruses
      E21, 27, 30, 31, and 33). Tests for neutralizing antibody were performed against
      the homologous viruses and against available regional homotypic strains.
      Heterotypic tests were performed against reoviruses 1-3, adenoviruses 1-31, and
      the entire series of enteroviruses (with the exception of enterovirus 68). The
      homologous geometric mean titre of the 5 echovirus antisera ranged from 3 000 to
      10 000; the titre of 1 coxsackievirus antiserum (A24) was only about 400, but the
      titres of the others ranged from 1 500 to 14 000. All corresponding
      preinoculation sera were negative. Heterotypic antibody of significant titre was
      found in 4 antisera: E31 serum against E5 virus, CA8 serum against CA3 virus,
      CA13 serum against CA18 virus, and CA15 serum against CA2 virus. Information on
      other heterotypic antibody titres (where found) is recorded for guidance in the
      use of the sera. The results of homotypic tests with viruses isolated by the
      collaborating laboratories, though limited in number, were satisfactory.

PMID- 4357976
TI  - Poliomyelitis: epidemiology and prophylaxis. 1. A longitudinal epidemiological
      survey in Kenya.
AB  - The results of a long-term survey of poliomyelitis in Kenya are reported. Virus
      was isolated from patients and a limited number of sera were also tested for
      antibodies. The purpose of the investigation was to elucidate the epidemiological
      characteristics of the disease and to determine whether epidemics could be
      predicted. A 3-year rhythm was found in the circulation of type 1 poliovirus,
      making possible the prediction and hence, on two occasions, the curbing or
      prevention of epidemics.

PMID- 4357977
TI  - Differential diagnosis of variola viruses by microfocus assay.
AB  - Variola virus was identified by means of a method involving the formation of
      microfoci on microplate cultures of HeLa cells. It was possible to distinguish
      between variola major and variola minor viruses within 48 h of receipt of the
      specimens by determining the temperature sensitivity of focus formation.

PMID- 4357978
TI  - [Chemistry of hypothalamic hypophysotropic hormones].

PMID- 4357979
TI  - Leukocytic enzyme differences between the clinical forms of malnutrition.

PMID- 4357980
TI  - [Mechanism of action of LH-RH].

PMID- 4357981
TI  - [Short feedback action of ACTH].

PMID- 4357982
TI  - Experimental myasthenia gravis, myositis and myocarditis in guinea-pigs immunized
      with subcellular fractions of calf thymus or calf skeletal muscle in Freund's
      complete adjuvant.

PMID- 4357985
TI  - Perspectives in molecular radiation biology. The biophysical approach.

PMID- 4357984
TI  - The catecholamines: reappraisal of their use for acute myocardial infarction and
      the low cardiac output syndromes.

PMID- 4357983
TI  - Macrophage and lymphocyte co-operation in target cell destruction in vitro.

PMID- 4357986
TI  - Properties of myeloma immunoglobulin E(Yu). Chemical, fluorescence polarisation
      and spin-labeled studies.

PMID- 4357987
TI  - Different sensitivity of ribonucleic and deoxyribonucleic acid viruses to
      resistance induced in rabbit cells (RK-13) by polyriboinosinic acid
      polyribocytidilic acid.
AB  - When a continuous line of rabbit kidney cells (RK-13) was exposed to
      polyriboinosinic acid polyribocytidilic acid [poly(rI).poly(rC)], the cells
      became resistant to the replication of a ribonucleic acid (RNA) virus, vesicular
      stomatitis (VSV), but remained susceptible to the replication of two
      deoxyribonucleic acid (DNA) viruses, pseudorabies and vaccinia. These differences
      were identical to previous findings with RK-13 cells pretreated with exogenous
      rabbit interferon. Confirmation is thereby provided that RK-13 cells are
      deficient in the synthesis of resistance factors active against the DNA viruses
      tested and that there are separate resistance factors for RNA and DNA viruses in
      RK-13 cells. The resistance against VSV which developed in RK-13 cells exposed to
      poly(rI).poly(rC) could be significantly reversed by prior infection with
      infective vaccinia virus but not by vaccinia inactivated by ultraviolet
      irradiation or heat.

PMID- 4357988
TI  - Induction of interferon in L cells by reoviruses.
AB  - L cell cultures challenged with reoviruses types 1 and 3 produced little to no
      detectable interferon under conditions which permitted virus replication and
      under conditions which prevented replication of a temperature-sensitive mutant
      strain of reovirus type 3 (ts-1). Ultraviolet-irradiated reoviruses and double
      stranded ribonucleic acids extracted from purified reovirus type 3 also induced
      little to no interferon in L cell cultures. Under similar conditions, MM virus
      proved to be an effective inducer of interferon. Exposure of L cells to
      interferon prior to challenge with virus (priming) failed to enhance interferon
      production upon subsequent challenge with reovirus although priming increased the
      amount of interferon produced following MM virus challenge. L cell cultures that
      were challenged with reovirus type 3 and subsequently with either MM or Colorado
      tick fever viruses produced similar titers of interferon as cell cultures that
      were challenged with either MM or Colorado tick fever virus alone, respectively.
      These data show that the presence of production of reovirus type 3 double
      stranded ribonucleic acid is not sufficient for induction of interferon in L cell
      cultures and that additional processes which are required for induction of
      interferon in L cell cultures are not expressed by reovirus type 3.

PMID- 4357989
TI  - Physical separation of streptococcal nicotinamide adenine dinucleotide
      glycohydrolase from streptolysin O.
AB  - Streptococcal nicotinamide adenine dinucleotide glycohydrolase (NADase) with a
      molecular weight of about 55,000 and an isoelectric pH of 8.55 was isolated from
      crude streptolysin O (SLO) preparations. NADase differed from SLO in size,
      charge, and immunological behavior. Streptococcal NADase is considered to have no
      role in the hemolytic process because it has no hemolytic activity; conversely,
      partially purified SLO showed no NADase activity. The hemolytic activity of crude
      SLO was completely inhibited by anti-tetanolysin, whereas the NADase activity in
      the same reaction mixture was unaffected. Experiments involving double diffusion
      in agar also demonstrated immunological nonidentity of the two proteins.

PMID- 4357991
TI  - Electron transfer in gamma-irradiated complexes between aromatic amino acids and
      DNA derivatives.

PMID- 4357990
TI  - Enhanced effect of repeated administration of bacterial vaccine against viral
      respiratory infection.
AB  - Administration of a standard bacterial vaccine (SBV) affords some protection
      against influenza infection in mice if given 4 to 5 h before inoculation of the
      virus. This effect was enhanced by repeated injections of SBV 7 and 14 days
      earlier, as measured by the length of survival, mortality rate, development of
      gross pneumonia, and virus multiplication in the lungs. Serum interferon levels
      were likewise enhanced by immunization with SBV, which may, at least in part,
      explain the increased preventive effect.

PMID- 4357992
TI  - Letter: Free radicals in the sugar moiety of x-irradiated DNA.

PMID- 4357993
TI  - Letter: E.s.r. of irradiated single crystals of cytosine.

PMID- 4357994
TI  - Letter: Multiplicity effect on the survival of ultra-violet-irradiated Herpes
      simplex virus.

PMID- 4357995
TI  - The effects of derivatives of adenosine 3',5'-monophosphate on fluid secretion by
      the salivary glands of Calliphora.

PMID- 4357996
TI  - A simple technique for monitoring the synaptic actions of pharmacological agents.

PMID- 4357997
TI  - [Lesion of collagen tissue in lathyrism with special reference to
      pathohistological and enzymohistological changes in the periodontal membrane].

PMID- 4357998
TI  - The composition of maternal plasma and foetal urine after feeding and drinking in
      chronically catheterized ewes during the last two months of pregnancy.
AB  - 1. The fluid sacs and bladders of sixteen foetuses in fourteen ewes were
      catheterized between 81 and 92 days gestational age and the rumens of four ewes
      were also catheterized.2. Between 95 and 145 days gestational age in forty-six 24
      hr experiments hourly samples of maternal plasma and foetal urine were obtained
      and in fifteen experiments foetal fluid samples were also taken at 4- to 6-hr
      intervals.3. The osmolality, pH, and concentrations of sodium, potassium,
      chloride, glucose, fructose and urea were measured on all samples.4. During
      experiment there was no significant variation in the composition of amniotic or
      allantoic fluid. Marked changes in osmolality occurred in maternal plasma and
      foetal urine when ewes drank after feeding, but not in ewes that received water
      intrarumenally via catheter while feeding or in fasting ewes. Post-prandial
      changes in maternal plasma osmolality may have altered transplacental water
      fluxes and as a result foetal plasma volume and osmolality.5. The results suggest
      that the foetus alters renal water retention by varying antidiuretic hormone
      (ADH) secretion in response to changes in blood volume and at later gestational
      ages plasma osmolality as well.6. Post-prandial changes in the [Na(+)]/[K(+)]
      ratio of foetal urine suggested that foetal adrenocorticotrophin (ACTH) secretion
      is influenced by variations in foetal blood volume and glucose concentrations.7.
      The post-prandial changes in foetal urine composition observed here support
      previous suggestions (Mellor & Slater, 1972) about the role of foetal urine in
      foetal fluid formation which were based on gestational changes in the composition
      of foetal fluids and urine sampled once daily during the post-absorptive state.

PMID- 4357999
TI  - The action of cobalt ions on neuromuscular transmission in the frog.
AB  - 1. Cobalt ions, in concentrations of 0.05-2 mM, block neuromuscular transmission
      in the frog sartorius muscle.2. The reduction in the e.p.p. amplitude produced by
      Co(2+) is due to a decrease in the amount of transmitter released by a nerve
      impulse (mean quantum content). This reduction is associated with little change
      in the resting membrane potential of the muscle fibre or in the mean amplitude of
      spontaneous m.e.p.p.s.3. The reduction in evoked transmitter release produced by
      Co(2+) may be antagonized by elevation of the external Ca(2+) concentration. It
      is suggested that the antagonism between Co(2+) and Ca(2+) is competitive in
      nature.4. The mean dissociation constant for Co(2+) and its hypothetical membrane
      complex was found to be 0.18 mM. On this basis, it is concluded that Co(2+) is
      about 20 times more potent than Mg(2+) in suppressing evoked transmitter
      release.5. In contrast to the inhibitory action on evoked release, Co(2+)
      increases spontaneous transmitter release. However, concentrations of Co(2+) 20
      60 times greater than those which decrease the e.p.p. amplitude are needed to
      produce a significant increase in m.e.p.p. frequency.

PMID- 4358000
TI  - Enzyme aspects of acute intermittent porphyria.

PMID- 4358001
TI  - Growth after adolescence.

PMID- 4358002
TI  - Leukocyte and placental metabolism as indices of fetal malnutrition.

PMID- 4358004
TI  - Standardized multisegmental measurements of blood pressure for quantitative
      evaluation of the circulation in the limbs.

PMID- 4358005
TI  - Induced hypertension in the treatment of severe foot ischemia.

PMID- 4358003
TI  - [Constants of acid-base equilibrium in the cerebrospinal fluid].

PMID- 4358006
TI  - Criticism about the use of muscles provided with a testosterone-binding protein
      to evaluate the miotrophic activity of androgens.

PMID- 4358007
TI  - Influence of adrenalectomy and beta-methasone on the composition of liver cell
      membrane.

PMID- 4358008
TI  - Fluoride uptake from prophylactic dentifrices. I. Methods for measuring fluoride
      uptake in tooth enamel in vitro and in vivo.

PMID- 4358009
TI  - Fluoride uptake from prophylactic dentifrices. II. Some introductory experiments
      and findings concerning in vitro fluoride uptake in tooth enamel.

PMID- 4358010
TI  - Studies on (8-14C) adenosine-5'-carboxylic acid ethyl ester. II. Incorporation of
      radioactivity into nucleic acids of mouse and dog.

PMID- 4358011
TI  - [Monitoring of kidney transplant recipients by the family doctor].

PMID- 4358012
TI  - Development of second-generation schizonts, gamonts and oocysts of Eimeria bovis
      in bovine kidney cells.

PMID- 4358013
TI  - [The significance of endodyogeny and schizogony in the Coccidia and other
      Sporozoa (author's transl)].

PMID- 4358014
TI  - In vitro perfusion of the human utero-tubo-ovarian unit.

PMID- 4358016
TI  - An improved method for the assay of hydroxylysine.

PMID- 4358015
TI  - Inappropriate renin secretion in pregnancy.

PMID- 4358017
TI  - An enzymatic method for measuring picomole quantities of acetylcholine and
      choline in CNS tissue.

PMID- 4358018
TI  - Improved rapidity and precision in the determination of brain 2',3'-cyclic
      nucleotide 3'-phosphohydrolase.

PMID- 4358019
TI  - A sensitive fluorometric assay for monoamine oxidase activity.

PMID- 4358020
TI  - Preparative solvent partition chromatography of butyrylated cyclic AMP analogues.

PMID- 4358021
TI  - Effect of cyclic AMP, theophylline and caffeine on the glucose repression of
      sporulation in Saccharomyces cerevisiae.

PMID- 4358022
TI  - Regulation in the chemolithotroph Thiobacillus neapolitanus: fructose-1,6
      diphosphatase.

PMID- 4358023
TI  - Drill biopsy of the breast--a critical analysis.

PMID- 4358024
TI  - [Drug-induced immune hemolytic anemias].

PMID- 4358025
TI  - Studies on in vitro synthesis and secretion of growth hormone and prolactin. II.
      Evidence against the existence of precursor molecules.

PMID- 4358026
TI  - Cyclic 3',5'-adenosine monophosphate in isolated bone cells. II. Responses to
      adenosine and parathyroid hormone.

PMID- 4358027
TI  - An investigation of progesterone receptors in guinea pig vagina, uterine cervix,
      mammary glands, pituitary and hypothalamus.

PMID- 4358028
TI  - Mechanism of action of gonadotropin. IV. Cyclic adenosine monophosphate-dependent
      translocation of ovarian cytoplasmic cyclic adenosine monophosphate-binding
      protein and protein kinase to nuclear acceptor sites.

PMID- 4358029
TI  - Cholesterol sulfate: some aspects of its biosynthesis and uptake by tissues from
      blood.

PMID- 4358030
TI  - Calcitonin and the formation of 3',5'-AMP in bone and kidney.

PMID- 4358031
TI  - Transfer ribonucleic acid in hepatoma tissue culture cells. II. Dexamethasone
      phosphate induction of tRNAphe analyzed under cell-free conditions.

PMID- 4358032
TI  - Glucagon and epinephrine activation of adenylate cyclase and glucagon binding in
      Morris hepatomas.

PMID- 4358034
TI  - Effects of prostaglandin antagonists on the induction of cyclic 3',5'-adenosine
      monophosphate formation and thyroid hormone secretion in vitro.

PMID- 4358033
TI  - Changes in thyroid ribonucleic acid, ribonucleases and alkaline ribonuclease
      inhibitor.

PMID- 4358035
TI  - Cyclic-AMP and the ocular responses to norepinephrine.

PMID- 4358036
TI  - Rescue of the murine sarcoma virus genome from non-producer cells by the RD-114
      type C virus.

PMID- 4358037
TI  - The effect of long-term exposure to DDT on CF-1 MICE.

PMID- 4358038
TI  - Cell-mediated destruction of Rous sarcomas in Japanese quails.

PMID- 4358039
TI  - Establishment of continuous lymphoblast cultures from leukocytes of gibbons
      (Hylobates lar).

PMID- 4358040
TI  - Surface antigen and polypseudopodia in abortive transformation of BHK 21 cells by
      polyoma virus.

PMID- 4358041
TI  - [Properties of an SV40-transformed hamster cell line resistant to actinomycin D
      (author's transl)].

PMID- 4358042
TI  - Re-exposure of human lymphoblastoid cell lines to Epstein-Barr virus.

PMID- 4358043
TI  - Regulation of maltodextrin phosphorylase synthesis in Escherichia coli by cyclic
      adenosine 3', 5'-monophosphate and glucose.
AB  - Cyclic adenosine 3', 5'-monophosphate (AMP) stimulates maltodextrin phosphorylase
      synthesis in Escherichia coli cells induced with maltose. A maximal effect occurs
      at 2 to 3 mM cyclic AMP. The action of cyclic AMP is specific, inasmuch as
      adenosine triphosphate, 3'-AMP, 5'-AMP, adenosine, and dibutyryl cyclic AMP are
      inactive. Glucose, alpha-methyl glucoside, 2-deoxyglucose, and pyridoxal 5'
      phosphate repress maltodextrin phosphorylase synthesis. This repression is
      reversed by cyclic AMP. The action of cyclic AMP appears to be at the
      transcriptional level, since cyclic AMP fails to stimulate phosphorylase
      production in induced cells in which messenger ribonucleic acid synthesis has
      been arrested by rifampin or by inducer removal. The two other enzymes involved
      in the metabolism of maltose, amylomaltase and maltose permease, are also induced
      in this strain of E. coli and affected by glucose and cyclic AMP in a manner
      similar to phosphorylase.

PMID- 4358044
TI  - Membrane permeability and the loss of germination factor from Neurospora crassa
      at low water activities.
AB  - Neurospora crassa conidia incubating in buffer at low water activities (a(w))
      release a germination-essential component as well as 260-nm absorbing and
      ninhydrin-positive materials, regardless of whether an electrolyte or non
      electrolyte is used to reduce a(w). Chloroform and antibiotics known to increase
      cell-membrane permeability have a similar effect. This suggests that membrane
      damage occurs in media of low a(w) and that an increase in permeability is
      responsible for the release of cellular components. The damage caused in media of
      low a(w) is nonlethal in most cases, and the conidia recover when transferred to
      nutrient medium.

PMID- 4358045
TI  - Lactose and D-galactose metabolism in group N streptococci: presence of enzymes
      for both the D-galactose 1-phosphate and D-tagatose 6-phosphate pathways.
AB  - Group N streptococci possess enzymes for the metabolism of d-galactose through
      both the d-galactose 1-phosphate pathway (Leloir pathway) and the d-tagatose 6
      phosphate pathway.

PMID- 4358046
TI  - Sporulation of Saccharomyces cerevisiae in the absence of a functional
      mitochondrial genome.
AB  - The role of the mitochondrial system during sporulation of Saccharomyces
      cerevisiae was studied. Addition of ethidium bromide (EthBr) to cells growing in
      acetate medium resulted in the quantitative (>98%) conversion of the culture to
      the petite genotype in one generation. The cells were respiratory active
      (derepressed) but contained no mitochondrial deoxyribonucleic acid (mtDNA) as
      demonstrated by analytical ultracentrifugation in CsCl. When transferred to
      acetate sporulation medium, the culture sporulated. Ascus production was only
      slightly below that of the control culture. Synthesis of mtDNA occurred during
      sporulation in the control but not in the EthBr-treated culture. Mitochondrial
      protein synthesis was virtually eliminated in the EthBr-treated culture.
      Therefore, completely derepressed cells can sporulate without a functional
      mitochondrial genetic system. When partially repressed cells were treated with
      EthBr, no ascus formation was observed after transfer to sporulation medium.
      Control cultures underwent respiratory adaptation in sporulation medium and then
      sporulated. Extensive derepression of the respiratory system is thus required for
      sporulation, and this adaptation is dependent on a functional mitochondrial
      system. Our results suggest that once the cells are fully derepressed no
      mitochondrial genetic information has to be expressed during meiosis and ascus
      formation.

PMID- 4358047
TI  - Germination of yeast spores lacking mitochondrial deoxyribonucleic acid.
AB  - A population of petite ascospores (mitochondrial deoxyribonucleic acid [mtDNA]
      less), produced by brief ethidium bromide (EthBr) mutagenesis prior to transfer
      to sporulation medium, was used to examine the role of the mitochondrial genetic
      system on germination and outgrowth in Saccharomyces cerevisiae. Petite
      ascospores, which are morphologically indistinguishable by phase-contrast
      microscopy from wild-type spores, germinate and proceed through outgrowth at a
      rate and extent only slightly less than that of wild-type spores. Both
      developmental processes occurred in the absence of mtDNA synthesis and measurable
      cytochrome oxidase activity. These results indicate that neither respiration nor
      a functional mitochondrial genome are required for germination and outgrowth. The
      properties of the petite clones were typical of petites formed during vegetative
      growth. Individual sporal clones differed markedly from each other in
      suppressiveness. Petite sporal clones which exhibited a high degree of
      supressiveness also contained a reduced but detectable amount of mtDNA of altered
      buoyant density. One clone contained a unique mtDNA with a buoyant density higher
      than that of wild-type mtDNA.

PMID- 4358048
TI  - Differential diagnosis of chronic orofacial pain.

PMID- 4358049
TI  - Disabling neuropathy associated with thymoma. Reversal by excision.

PMID- 4358050
TI  - [Application of a scintillation camera for differential diagnosis of meningioma
      and glioblastoma].

PMID- 4358051
TI  - [Course of mixed influenza-adenovirus infection in adults].

PMID- 4358052
TI  - [Late generalized Thorotrast injuries].

PMID- 4358053
TI  - Letter: Abdominal pain in hyperlipoproteinemia.

PMID- 4358054
TI  - The nitroblue tetrazolium reduction test versus conventional hematology in the
      diagnosis of bacterial infection.

PMID- 4358055
TI  - Zoster immune globulin. A further assessment.

PMID- 4358056
TI  - Case records of the Massachusetts General Hospital. Weekly clinicopathological
      exercises. Case 4-1974.

PMID- 4358057
TI  - Evidence for a junctional effect of lead on neuromuscular function.

PMID- 4358058
TI  - About the neurological sequelae of herniated intravertebral disc.

PMID- 4358059
TI  - Proceedings: Human leukocyte antigens and ABO blood groups in gestational
      trophoblastic neoplasms.

PMID- 4358060
TI  - Proceedings: Hormonal relations of endometrial cancer.

PMID- 4358062
TI  - Proceedings: Lectin monitored surface changes in transformed and mitotic normal
      cells.

PMID- 4358061
TI  - Proceedings: Xeroradiography of the breast.

PMID- 4358063
TI  - Proceedings: Genetics and the cancer cell: cell growth regulation.

PMID- 4358064
TI  - Proceedings: Tumors of the adrenal cortex and Cushing's syndrome.

PMID- 4358065
TI  - Proceedings: Islets of Langerhans.

PMID- 4358066
TI  - Proceedings: Genetics and the cancer cell: cell genetics and growth of endogenous
      viruses.

PMID- 4358067
TI  - Proceedings: Soft part sarcomas in children--1972.

PMID- 4358068
TI  - Proceedings: The national Wilms' tumor study: a progress report.

PMID- 4358069
TI  - Proceedings: Survival of lung cancer patients vis-a-vis therapy and cell type.

PMID- 4358070
TI  - Proceedings: Carcinoma of the lung at the New York Hospital-Cornell Medical
      Center (1964-1968).

PMID- 4358071
TI  - Proceedings: Immunological investigations on human brain tumor patients.

PMID- 4358072
TI  - Proceedings: Chemotherapy of soft-tissue sarcomas.

PMID- 4358073
TI  - Synaptic transmission between photoreceptors and horizontal cells in the turtle
      retina.
AB  - Low calcium, high magnesium, and cobalt hyperpolarize the horizontal cell
      membrane and suppress the response to light, but only partially affect the
      response of receptor cells. These observations are consistent with the
      interpretation that a depolarizing transmitter is released by photoreceptors in
      darkness. The hyperpolarizing response to light of the horizontal cells would
      then result from a reduction in the amount of transmitter released.

PMID- 4358074
TI  - High-frequency C-type virus induction by inhibitors of protein synthesis.
AB  - When inhibitors of protein synthesis are added to BALB/c mouse cells in culture,
      induction of naturally integrated C-type RNA virus occurs in a high percentage of
      cells. The action of protein synthesis inhibitors differs from that of
      halogenated pyrimidines, another class of virus inducers, in their effects on
      biologically distinguishable viruses. The use of such inhibitors to study
      integrated virus expression provides a means for studying gene regulation in
      mammalian cells.

PMID- 4358075
TI  - Reduction of ferricytochrome c by some free radical agents.
AB  - Fast pulse radiolysis and kinetic spectroscopy were used to rapidly generate a
      variety of free radicals in situ and study their reactions with ferricytochrome c
      in the time range 10(-6) to 1 second. The radicals included t-butanol, which is
      inert to ferricytochrome c; malate, lactate, and ethanol, which react with it
      relatively slowly but are completely utilized in reducing it to ferrocytochrome
      c; and hydrated electrons and hydrogen atoms, which react with it very rapidly
      but yield ferrocytochrome c only in part, showing intramolecular consecutive
      reactions and further attack on the ferrocytochrome c protein. From a detailed
      comparison between malate and hydrogen atoms it is argued that malate reacts
      directly and selectively with a specific part of the ferricytochrome c surface
      while hydrogen atoms react with other parts of the protein too, yielding radicals
      which in part transfer intramolecularly to yield ferrocytochrome c.

PMID- 4358076
TI  - Protein kinase translocation as an early event in the hormonal control of uterine
      contraction.
AB  - beta-Adrenergic stimulation with isoproterenol inhibits contractility, increases
      cyclic adenosine monophosphate (AMP) concentration, decreases the concentration
      of unsaturated cyclic AMP receptor sites, and increases cyclic AMP-independent
      kinase in the uterus of ovariectomized rats. The total soluble kinase activity is
      reduced. The protein kinase activity lost from the cytosol was translocated to
      the microsomal fraction mostly in a cyclic AMP-independent form, suggesting a
      particulate substrate for the activated enzyme.

PMID- 4358077
TI  - Proton relaxation rates of water in brain and brain tumors.
AB  - The distribution of relaxation rates of water in "normal" (autopsy) samples of
      canine and human brain shows considerable overlap with that for brain tumor
      samples. The following ranges of values for the spin-spin relaxation rates were
      observed: for normal brain gray matter, 8.6 to 11.3 sec(-1) (mean, 9.5 sec(-1));
      for normal brain white matter, 13.3 to 15.7 sec(-1) (mean, 15.5 sec(-1)); for six
      types of malignant tumor, 4.8 to 13.4 sec(-1) (mean, 9.3 sec(-1)); for five types
      of benign tumor, 7.1 to 16.4 sec(-1) (mean, 11.5 sec(-1)). Spin-lattice
      relaxation rates showed a similar pattern. At least two nonexchanging water
      components with different relaxation rates were indicated by the analysis of the
      spin-spin relaxation measurements for the white matter samples.

PMID- 4358079
TI  - [Objectivization of the nerve block effect].

PMID- 4358078
TI  - Cholinergic mechanism in the cerebrovascular action of carbon dioxide.

PMID- 4358080
TI  - [Paroxysmal bioelectrical brain activity in patients with extrapyramidal
      disorders of the nervous system].

PMID- 4358081
TI  - Thyroid optic neuropathy: to decompress or not?

PMID- 4358082
TI  - Rapid adiabatic passage EPR of ferricytochrome c: signal enhancement and
      determination of the spin-lattice relaxation time.

PMID- 4358083
TI  - Studies of the metal sites of copper proteins. V. A model compound for the copper
      site of superoxide dismutase.

PMID- 4358084
TI  - Conformational studies on modified proteins and peptides. VII. Conformation of
      epsilon-prototoxin and epsilon-toxin from Clostridium perfringens. Conformational
      changes associated with toxicity.

PMID- 4358085
TI  - Preparation of photo-affinity probes for the insulin receptor site in adipose and
      liver cell membranes.

PMID- 4358086
TI  - Phosphorylation of surface proteins of HeLa cells using an exogenous protein
      kinase and (gamma-32P)ATP.

PMID- 4358087
TI  - A partially purified membrane protein specific to the brain.

PMID- 4358088
TI  - Monoiodinated angiotensins: preparation and characterization by polyacrylamide
      gel electrophoresis and isoelectric focusing.

PMID- 4358089
TI  - Electron nuclear double resonance studies on heme proteins: interaction of the
      electron spin with the 57Fe3+ nucleus in metmyoglobin and methemoglobin.

PMID- 4358090
TI  - Analysis of polar parts of phospholipids. N-demethylation of choline-containing
      lipids for gas chromatography and mass spectrometry.

PMID- 4358091
TI  - Triphosphoinositide phosphodiesterase in a protozoan-Crithidia fasciculata.

PMID- 4358092
TI  - Improved conditions for the preservation and extraction of polyphosphoinositides.

PMID- 4358093
TI  - The subcellular distribution of polyphosphoinositides in myelinated and
      unmyelinated rat brain.

PMID- 4358094
TI  - Blood group A active ceramide hexasaccharide lacking N-acetylglucosamine isolated
      from hog stomach mucosa.

PMID- 4358095
TI  - The influence of extracellular calcium ion on hormone-activated lipolysis.

PMID- 4358096
TI  - The detection of linoleic acid radicals in the anaerobic reaction of
      lipoxygenase.

PMID- 4358097
TI  - Attempts to reverse the effects of disuse in the lateral geniculate nucleus of
      the cat.

PMID- 4358098
TI  - Influence of L-DOPA on transmission in long ascending propriospinal pathways in
      the cat.

PMID- 4358099
TI  - Restoration of locomotor activity in mice by low L-DOPA doses after suppression
      by alpha-methyltyrosine but not by reserpine.

PMID- 4358100
TI  - Effects of stimulation of the vestibular labyrinth on intracellular responses of
      spinal motoneurons in the pigeon.

PMID- 4358101
TI  - Tetrodotoxin resistant electrically excitable responses of receptor cells.

PMID- 4358102
TI  - [Combination of ACTH dexamethazone and HCG in the differential diagnosis of
      hirsutism and polycystic ovaries (author's transl)].

PMID- 4358103
TI  - [Diagnosis and therapy of threatened pregnancies by means of synthetic ACTH
      (author's transl)].

PMID- 4358104
TI  - Demonstration of hyper-alpha-lipoproteinemia in three diabetic patients.

PMID- 4358105
TI  - The brain and sodium homeostasis.

PMID- 4358106
TI  - The evolution of EEG features in infantile spasms: a prospective study.

PMID- 4358107
TI  - The syndrome of inappropriate secretion of antidiuretic hormone (SIADH).

PMID- 4358108
TI  - [Experimental studies on malocclusion related to nocturnal activity of
      masticatory muscles].

PMID- 4358109
TI  - The effect of pertussis adjuvant on antibody production: the need for thymus
      dependent lymphocytes.

PMID- 4358110
TI  - Isolation and characterization of an adherent, 8-azaguanine resistant variant of
      the Burkitt lymphoma cell line, Raji.

PMID- 4358111
TI  - Acrosomal ATPase in starfish and bivalve mollusk spermatozoa.

PMID- 4358112
TI  - Enzyme microelectrophoresis of cell colonies.

PMID- 4358113
TI  - Endocytosis in Chinese hamster fibroblasts. Inhibition by glucose.

PMID- 4358114
TI  - Activation of phosphorylase in sea urchin eggs by Ca2+ and cyclic 3'5'-AMP. A
      possible mechanism of the regulation of its activity at fertilization.

PMID- 4358116
TI  - Studies of inhibitors of bone marrow colony formation in normal human sera and
      during a viral infection.

PMID- 4358117
TI  - Preferential retention of the human chromosome C-7 in human-(thymidine kinase
      deficient) mouse hybrid cells.

PMID- 4358115
TI  - Preparation of rat liver cells. 3. Enzymatic requirements for tissue dispersion.

PMID- 4358118
TI  - Identification of N,N-dimethyltryptamine, 5-methoxy-N,N-dimethyltryptamine and
      bufotenin by cellulose TLC.

PMID- 4358119
TI  - Medical problems in chronic alcoholic men.

PMID- 4358120
TI  - Effects of idoxuridine on Herpesvirus hominis encephalitis and disseminated
      infections in marmosets.

PMID- 4358121
TI  - Adenovirus vaccines in military recruit populations: a cost-benefit analysis.

PMID- 4358122
TI  - Role of mosquitoes in the spread of smallpox.

PMID- 4358123
TI  - Effect of proteolytic enzymes on the infectivity of a number of herpesviruses.

PMID- 4358124
TI  - The two sites of penicillin action in Escherichia coli.

PMID- 4358125
TI  - Viruses causing common respiratory infection in man. IV. Reoviruses and
      Adenoviruses.

PMID- 4358127
TI  - On the origin of oligomer forms of polyoma DNA.

PMID- 4358126
TI  - Xeroderma pigmentosum cell susceptibility to SV40 virus transformation: lack of
      effect of low dosage ultraviolet radiation in enhancing viral-induced
      transformation.

PMID- 4358128
TI  - Editorial: Role of the megakaryocyte and platelet in the leukemic process in mice
      and men--a review and hypothesis.

PMID- 4358129
TI  - Factors affecting glycogen levels in HeLa cells: prednisolone and adenine
      nucleotides.

PMID- 4358131
TI  - Lung cancer in women: present and future trends.

PMID- 4358130
TI  - Antibodies to Epstein-Barr virus-related antigens in nasopharyngeal carcinoma.
      Comparison of active cases with long-term survivors.

PMID- 4358132
TI  - Prevalence of type-C virus and antibodies in normal cats and cats with neoplasia.

PMID- 4358133
TI  - Virus-chemical carcinogenesis: a possible viral immunologic influence on 3
      methylcholanthrene sarcoma induction.

PMID- 4358135
TI  - Detection of hamster type-C virus antigens by the passive hemagglutination
      technique.

PMID- 4358134
TI  - A new group of oncogenic viruses: reticuloendotheliosis, chick syncytial, duck
      infectious anemia, and spleen necrosis viruses.

PMID- 4358136
TI  - Studies of FBJ osteosarcoma virus in tissue culture. I. Biologic characteristics
      of the "C"-type viruses.

PMID- 4358137
TI  - Oncogenicity of Herpesvirus ateles in monkeys.

PMID- 4358138
TI  - Oncogenic potential of murine C-type RNA virus passaged directly from naturally
      occurring tumors of the BALB-cCr mouse.

PMID- 4358140
TI  - Abelson virus activity in mice and rats neutralized with anti-Rauscher virus
      serum.

PMID- 4358141
TI  - Antibodies reacting to Simian virus 40 T antigen in human sera.

PMID- 4358139
TI  - Comparative characterization of a C-type virus-producing cell line (VSW) and a
      virus-free cell line (VH2) from Vipera russelli.

PMID- 4358142
TI  - Induction of tubular structures in the endoplasmic reticulum of human lymphoid
      cells by treatment with 5-bromo-2'-deoxyuridine.

PMID- 4358143
TI  - Kinetics of nitrosation of the amino acids proline, hydroxyproline, and
      sarcosine.

PMID- 4358144
TI  - Toxic metabolites released from rat hepatoma cells in culture. I. Effects of
      metabolites of hepatomas on various cells.

PMID- 4358145
TI  - Cultivation and characterization of BALB-cfC3H mammary tumor cell lines.

PMID- 4358146
TI  - Selection of tumor-host cell hybrids from polyoma virus- and methylcholanthrene
      induced sarcomas.

PMID- 4358147
TI  - Histopathology of tumor regression after intralesional injection of Mycobacterium
      bovis. IV. Development of immunity to tumor cells and BCG.

PMID- 4358148
TI  - High resolution autoradiographic study of the kinetics of development of Rous
      sarcoma virus (Schmidt-Ruppin strain). V. Estimation of the time of synthesis of
      virus-associated DNA.

PMID- 4358149
TI  - In vivo inoculation of RNA C-type viruses inducing regression of experimental
      solid tumors.

PMID- 4358150
TI  - Antibody patterns to Herpesvirus saimiri-induced antigens in owl monkeys.

PMID- 4358151
TI  - Interactions of early mouse embryos with oncogenic viruses--simian virus 40 and
      polyoma. I. Ultrastructural studies.

PMID- 4358152
TI  - Transplacental effects of 1-ethyl-1-nitrosourea in inbred strains of mice. 3.
      Association between infectious or subinfectious endogenous type-C RNA tumor virus
      expression and chemically induced tumorigenesis.

PMID- 4358153
TI  - Expression of A- and C-type particles in early mouse embryos.

PMID- 4358154
TI  - Oral excretion of Herpesvirus saimiri in captive squirrel monkeys and incidence
      of infection in feral squirrel monkeys.

PMID- 4358155
TI  - Transplantation of chemically induced metastatic mucinous adenocarcinomas of the
      jejunum and colon in rats.

PMID- 4358156
TI  - 5'-Nucleotide phosphodiesterase isoenzyme and hepatic cancer in NCI-Mayo Clinic
      panel sera.

PMID- 4358157
TI  - Reassociation kinetics for Epstein-Barr virus DNA: nonhomology to mammalian DNA
      and homology of viral DNA in various diseases.
AB  - The number of Epstein-Barr virus (EBV) genomes per cell in established leukocytic
      lines and tissue specimens has been evaluated by measuring DNA-DNA reassociation
      kinetics with hydroxyapatite chromatography. Under the proper conditions, this
      method is sufficiently sensitive to detect EBV DNA in the amount of 0.1 genome
      per cell. All the samples tested that have been suspected to be without EBV DNA
      by cRNA hybridization proved negative by this more sensitive specific analysis.
      These included Hela and Hep2 cells, a negative case of Burkitt's lymphoma, two
      negative cases of nasopharyngeal carcinoma, and two established human leukocytic
      lines. Homology tests conducted with single-strand-specific nuclease S1 indicated
      that the viral DNA from a nasopharyngeal carcinoma and infectious mononucleosis
      were more than 90% homologous to EBV DNA.

PMID- 4358158
TI  - Alteration in tRNA methyltransferase activity in mengovirus infection: host range
      specificity.
AB  - The tRNA methyltransferase activity in mengovirus-infected L cells, HeLa cells,
      and Maden Derby bovine kidney cells has been examined during the course of
      infection. The first two cell lines yield a productive infection, but have
      different kinetics of inhibition of host RNA synthesis, whereas the bovine kidney
      cells are a restrictive host. In infected L cells the enzymes show altered
      capacity and base specificity throughout the infection. In infected HeLa cells
      and in infected bovine kidney cells less marked changes were seen. No inhibitors
      or activators of the enzymes were detected in any of the infected cell lines.
      Labeling experiments in infected cells indicated that in infected L cells
      synthesis of RNA was inhibited to a greater degree than was methylation of RNA.
      The consequence of this would be a hypermethylation of RNA. The methylated
      derivatives synthesized in infected L cells showed changes in relative
      proportions. Infection of HeLa cells and bovine kidney cells did not show such
      marked effects on methylation of RNA.

PMID- 4358160
TI  - Strandedness and complementarity of DNA from long-term RNA-dependent DNA
      polymerase reactions of Soehner-Dmochowski murine sarcoma virus.
AB  - The DNA product of the endogenously instructed RNA-dependent DNA polymerase
      reaction of murine sarcoma virus continued to be synthesized for as long as 64 h
      in the presence of 0.008% Triton X-100. Higher detergent concentrations and
      actinomycin D inhibited DNA product synthesis. The DNA product from long-term
      polymerase reactions consisted of small DNA fragments as shown by sedimentation
      in alkaline sucrose gradients. The enzymatic DNA product was separated into a
      slow sedimenting fraction and a fast sedimenting fraction by rate-zonal
      centrifugation. Fast sedimenting DNA was the predominant fraction made in viral
      polymerase reactions containing 262 mM NaCl. By using a combination of S-1
      nuclease and pancreatic RNase A, the amount of single-stranded DNA, double
      stranded DNA, and DNA-RNA hybrid present in the slow-sedimenting and fast
      sedimenting fractions was determined. Under standard polymerase conditions of 70
      mM NaCl, single-stranded DNA was the major form of DNA found in both fractions.
      In contrast, the prevalent form of DNA made in the presence of 262 mM NaCl was
      DNA-RNA hybrid. Hybridization studies in which either S-1 nuclease or pancreatic
      RNase A was used to measure hybrid formation demonstrated not only that the DNA
      product was complementary in base sequence to the RNA genome, but also that at
      least 79 to 84% of the RNA genome was transcribed into complementary DNA.

PMID- 4358159
TI  - Cell-free translation of paramyxovirus messenger RNA.
AB  - Polypeptides corresponding in electrophoretic mobility to virion polypeptides 1,
      3, and 5 were made in a reticulocyte cell-free system to which 18S RNA from
      Sendai virus-infected cells was added. Immune precipitation was used to select
      relevant polypeptides from endogenous products. The cell-free product
      corresponding to virion polypeptide 3 (the nucleocapsid structure unit) was the
      most abundant; its tryptic peptides comigrated electrophoretically with tryptic
      peptides of polypeptide 3 isolated from virions. Other sedimenting classes of RNA
      from infected cells were tested; only the 28S fraction showed slight activity.
      Virion 50S RNA was inactive. These findings support the hypothesis that
      complementary RNA transcripts of paramyxovirion RNA are the templates for viral
      proteins.

PMID- 4358161
TI  - Polyoma pseudovirions. II. Influence of host cell on pseudovirus production.
AB  - The type of host cell influenced the relative amounts of pseudovirions and
      polyoma virions produced. The infection of primary mouse embryo cells resulted in
      the production of particles that were predominantly pseudovirions. Infection of
      baby mouse kidney or 3T3D cells yielded mainly infectious polyoma virus. The
      length of time that infection was allowed to continue also affected the amount of
      pseudovirions relative to polyoma virions. The longer the viral infection was
      allowed to proceed, the greater the quantity of pseudovirions produced.
      Pseudovirion production could be correlated with the fragmentation of host cell
      DNA to a size of approximately 3 x 10(6) daltons. The fragmentation of host cell
      DNA was much more extensive in primary mouse embryo cells than in the other cell
      types.

PMID- 4358162
TI  - Structural characteristics and nucleotide sequence analysis of genomic RNA from
      RD-114 virus and feline RNA tumor viruses.
AB  - The results of molecular hybridization experiments have demonstrated that the RNA
      genome of RD-114 virus has extensive nucleotide sequence homology with the RNA
      genome of Crandell virus, an endogenous type C virus of cats, but only limited
      homology with the RNA genomes of feline sarcoma virus and feline leukemia virus.
      The genomic RNAs of RD-114 virus and Crandell virus also had identical
      sedimentation coefficients of 50S. A structural rearrangement of genomic RNA did
      not exist within released RD-114 virions, whereas a structural rearrangement of
      genomic RNA did occur within feline sarcoma virions and feline leukemia virions
      after release from virus-producing cells.

PMID- 4358164
TI  - Morphogenesis of poliovirus. II. Demonstration of a new intermediate, the
      proviron.
AB  - Poliovirus-infected cells contain a previously unrecognized particle which
      appears to be an intermediate in virion synthesis and therefore has been named
      proviron. It sediments at about 125S, contains the three procapsid proteins, VP
      0, VP-1, and VP-3, and has 35S viral RNA. It is disrupted both by sodium dodecyl
      sulfate and EDTA but the RNA resists digestion by ribonuclease. Pulsechase
      experiments and studies employing the virus-specific inhibitor, guanidine, all
      indicate that the proviron is formed by combination of newly made RNA with the
      procapsid. Cleavage of VP-0 to form VP-2 and VP-4 follows formation of the
      provirion and would be the final step in poliovirus morphogenesis.

PMID- 4358163
TI  - Cell surface antigens associated with murine leukemia virus: definition of the GL
      and GT antigenic systems.
AB  - Two new serological specificities were identified on the surface of murine
      leukemia virus (MuLV)-infected cells by direct and absorption immunofluorescence
      tests. Both antigens were detected with antisera prepared in rats that were
      growing transplants of syngenic MuLV-induced leukemias. Antigen G(L) was defined
      with the AKR leukemia K36 as the test cell; antigen G(T) was defined with the
      W/Fu leukemia C58(NT)D as the test cell. G(L) and G(T) antigens were
      serologically and genetically independent of the MuLV-induced Gross and G(IX)
      cell-surface antigens. G(L) and G(T) antigens were found in normal lymphoid cells
      of mice from high-leukemic strains, but not in lymphoid tissues of mice from most
      low-leukemic strains. Tumors and leukemias of mice of low-leukemic strains often
      were G(L) and G(T) positive. Similarly, infection of normal cells with MuLV
      resulted in expression of G(L) and G(T). With ferritin-labeled antibody the G(L)
      and G(T) antigens were observed on virus-free segments of the cell surface.
      Genetically, G(L) and G(T) antigens were each controlled by two dominant unlinked
      genes in AKR mice; these same antigens were each controlled by three or more
      dominant unlinked genes in C58 mice. Penetrance of G(L) and G(T) regulatory genes
      was dependent upon the Fv-1 genotype of the host. Expression of G(L) antigen was
      closely associated with virus production, whereas expression of G(T) antigen was
      less closely associated.

PMID- 4358165
TI  - Morphogenesis of poliovirus 3. Formation of provirion in cell-free extracts.
AB  - Formation of an apparent virion precursor, the provirion, can be demonstrated in
      cytoplasmic extracts of poliovirus-infected HeLa cells.

PMID- 4358166
TI  - Simian virus 40-host cell interactions. I. Temperature-sensitive regulation of
      SV40 T antigen in 3T3 mouse cells transformed by the ts*101 temperature-sensitive
      early mutant of SV40.
AB  - BALB/3T3 and Swiss/3T3 mouse cells transformed at permissive temperature (33 C)
      by the early temperature-sensitive mutant of simian virus 40 (SV40), ts(*)101,
      exhibited a temperature-dependent modulation of SV40 tumor (T) antigen as assayed
      by immunofluorescence. The percentage of T antigen-positive nuclei in ts(*)101
      transformed cells was reduced at restrictive temperature (39 C) when compared to
      33 C and to wild-type SV40 transformed cells at either 33 C or 39 C. The
      percentage of T antigen-positive nuclei in ts(*)101 transformed cells returned to
      the 33 C control level when the cells were shifted from 39 to 33 C. The ts(*)101
      transformed cells could be superinfected with wild-type, but not ts(*)101,
      virions at 39 C as assayed by an increase in T antigen-positive nuclei.

PMID- 4358168
TI  - Determination of the molecular weight of animal RNA viral genomes by nuclease
      digestions. I. Vesicular stomatitis virus and its defective T particle.
AB  - A procedure has been developed for the determination of the weight of animal RNA
      virus genomes using controlled nuclease digestions and computation of the moles
      of oligonucleotides obtained from 1 mol of RNA. Using both pancreatic RNase and
      RNase T(1) to digest viral RNA labeled by (3)H-uridine, (3)H-cytidine, or (3)H
      guanosine, the weight of the virion RNA of vesicular stomatitis virus (VSV) is
      estimated as 3.82 +/- 0.14 x 10(6) whereas that of the VSV-defective T particle
      is estimated as 1.23 +/- 0.04 x 10(6).

PMID- 4358167
TI  - RNA-dependent RNA polymerase in nuclei of cells infected with influenza virus.
AB  - Nuclei purified from chicken embryo fibroblast cells infected with influenza
      (fowl plague) virus contain an RNA-dependent RNA polymerase. The in vitro
      activity of this enzyme is insensitive to actinomycin D, and is completely
      destroyed by preincubation with ribonuclease. Enzyme induction is prevented if
      cells are treated with actinomycin D or cycloheximide at the time of infection.
      RNA-dependent RNA polymerase activity increases rapidly in cell nuclei from 1 h
      postinfection, reaches a maximum at 3 to 4 h, then declines; a similar RNA
      polymerase activity in the microsomal cell fraction increases from 2 h
      postinfection and reaches a maximum at 5 to 6 h. The characteristics of the
      nuclear and microsomal enzymes in vitro are similar with respect to pH and
      divalent cation requirements. The in vitro products of enzyme activity present in
      the nuclear and microsomal fractions of cells infected for 3 and 5 h were
      characterized by sucrose density gradient analysis, and annealing to virion RNA.
      The microsomal RNA polymerase product contained 67 and 93% RNA complementary to
      virion RNA at 3 and 5 h, respectively; for the nuclear RNA polymerase product
      these values were 40% in each case.

PMID- 4358170
TI  - Viruses as precipitants of asthmatic attacks in children.

PMID- 4358169
TI  - RD 114 virus-specific sequences in feline cellular RNA: detection and
      characterization.
AB  - RNA extracted from cat cells contains sequences homologous to RD-114 viral RNA.
      The sequences are measured by molecular hybridization with a single-stranded DNA
      probe synthesized by the virion polymerase using the endogenous viral RNA as
      template. Viral-specific RNA has been detected in all cells of cat origin tested
      thus far, but not in cells of other animals, except for the virus-producing human
      rhabdomyosarcoma cell, RD-114. The extent of hybridization of the DNA probe to
      cellular RNA was equivalent to that obtained with viral 70S RNA indicating that
      an equal extent of viral specific sequences is present in all cat cells as well
      as in RD-114 cells. The amounts of this viral RNA reach approximately 100 copies
      per cell in cat cells, while virus-producing RD-114 cells contain about 1,000
      copies per cell. The viral RNA is present in cat cells in two distinct sizes of
      about 35S and 18S, whereas in RD-114 cells virus-specific RNA is quite
      heterogeneous in size.

PMID- 4358172
TI  - Letter: Imipramine and enuresis.

PMID- 4358171
TI  - Letter: Topical application of cyclic AMP in psoriasis.

PMID- 4358173
TI  - Phenotypic mixing of vesicular stomatitis virus with HVJ (Sendai virus).

PMID- 4358174
TI  - [The preternatural anus. Establishment, complications and after-care].

PMID- 4358176
TI  - Effect of exogenous oestrogens on minor psychiatric symptoms in postmenopausal
      women.

PMID- 4358175
TI  - Radiological experience with nasopharyngeal masses.

PMID- 4358177
TI  - [A theory of the mechanisms responsible for the side-effects of suxamethonium
      (author's transl)].

PMID- 4358179
TI  - [Abrikossoffs tumour of the vulva with recurrence and metastasis (author's
      transl)].

PMID- 4358178
TI  - [The alveolar carcinoma. 3. Genesis and particularities (author's transl)].

PMID- 4358180
TI  - [Morphological changes in the liver of chronic alcoholics without internal
      diseases and their diagnostic evaluation (author's transl)].

PMID- 4358181
TI  - [Acute necrotizing Herpes-encephalitis presenting ischemic brain infarct
      (author's transl)].

PMID- 4358182
TI  - [Histochemical and biochemical ferment studies on the placenta following glucose
      infusion in the mother].

PMID- 4358183
TI  - Mannosidosis: clinical, fine-structural and biochemical findings in three cases.

PMID- 4358185
TI  - Comparative measurements of enzyme activities and 2,3-diphosphoglycerate in the
      erythrocytes of newborns with transitory hyperbilirubinaemia.

PMID- 4358184
TI  - Renal function in long-term survivors after treatment for nephroblastoma.

PMID- 4358186
TI  - Adrenal glucocorticoid function in acute viral infections in children.

PMID- 4358187
TI  - Investigations on the effects of diethazine on neuromuscular transmission in the
      rat.

PMID- 4358188
TI  - Interrelationship between bacterial histidine decarboxylase activity and
      concentration of histidine and pyridoxal-5'-phosphate.

PMID- 4358189
TI  - Cyclic GMP and gastric acid secretion.

PMID- 4358190
TI  - A guide for drug use in depressive disorders.

PMID- 4358191
TI  - Comprehensive training in forensic psychiatry.

PMID- 4358192
TI  - Determination of sedimentation coefficients of subcellular particles of rat liver
      homogenates. A theoretical and experimental approach.

PMID- 4358193
TI  - Adenosine 3',5' cyclic monophosphate assay at 10-15 mole level.

PMID- 4358194
TI  - Orthophosphate analysis by the Fiske-SubbaRow method and interference by
      adenosine phosphates and pyrophosphate at variable acid pH.

PMID- 4358195
TI  - Determination of 25-hydroxycholecalciferol by combined thin layer and gas
      chromatography.

PMID- 4358197
TI  - [Ultrastructure of the epithelium and endothelium of the small intestine blood
      capillaries exposed to choleragen].

PMID- 4358196
TI  - Clinical observations on response to nasal occlusion in infancy.

PMID- 4358198
TI  - [Change in the biochemical properties of bacteria as a result of adaptation to
      plants].

PMID- 4358199
TI  - Genetic determinants of aminoglycoside resistance in strains of Mycobacterium
      tuberculosis.

PMID- 4358200
TI  - [On adrenal tumors and hypertensinogenic retroperitoneal tumors].

PMID- 4358201
TI  - Cellophane perinephritis hypertension and its reversal in rabbits. Effect on
      plasma renin, renin substrate, and renal mass.

PMID- 4358202
TI  - Adrenergic control of the peripheral circulation in cardiomyopathic hamsters with
      heart failure.

PMID- 4358203
TI  - Glutamine phosphoribosylpyrophosphate amidotransferase.

PMID- 4358204
TI  - Protein kinases.

PMID- 4358206
TI  - [Multiple sclerosis].

PMID- 4358205
TI  - The effect of ACTH and cortisone on gastric acid mucosubstances in rats.

PMID- 4358208
TI  - [Insular hyperplasia. Study of 148 cases].

PMID- 4358207
TI  - The effects of delta8-THC on the EEG, reticular multiple unit activity and sleep
      of cats.

PMID- 4358210
TI  - [Functioning beta-insular tumors of the pancreas. Clinical study of 1067 cases].

PMID- 4358209
TI  - [Functioning beta-insular tumors of the pancreas. Principal diagnostic tests].

PMID- 4358212
TI  - [Current solutions of the therapeutic problem of hyperinsulinism caused by
      intractable beta-insular adenoma].

PMID- 4358211
TI  - [Indications and medical therapy of hypoglycemic beta-insular].

PMID- 4358213
TI  - [Surgical treatment of hypoglycemic tumors of the pancreas].

PMID- 4358214
TI  - [Some morphological data on pancreatic neoplasms associated with
      hyperinsulinism].

PMID- 4358216
TI  - [Circadian aspects of the ACTH-secretory system in essential arterial
      hypertension].

PMID- 4358215
TI  - [Influence of cyclic AMP on hypothalamo-hypophyseal regulation of secretion of
      somatotropin].

PMID- 4358217
TI  - [Value of cytohormonal, cytoenzymatic and histochemical studies of the vaginal
      epithelium in normal pregnancy and its complications].

PMID- 4358218
TI  - Analytical studies on ergot alkaloids and their derivatives. I. Separation of
      ergot alkaloids of the ergotoxine and ergotamine groups by thin-layer
      chromatography.

PMID- 4358219
TI  - Thin-layer chromatographic behaviour of the acetates of some polyfunctional
      diterpene alcohols of toxicological interest.

PMID- 4358222
TI  - Synthesis and enzymic studies of 5-aminoimidazole and N-1-and N6-substituted
      adenine ribonucleoside cyclic 3',5'-phosphates prepared from adenosine cyclic
      3',5'-phosphate.

PMID- 4358223
TI  - Lipolytic activity of Met-Arg-His-Phe-Arg-Trp-Gly, a synthetic analog of the ACTH
      (4-10) core sequence.

PMID- 4358224
TI  - Potential antidiabetic agents. Pyrazolo(3,4-b)pyridines.

PMID- 4358225
TI  - Nucleic acid and polyamine synthesis in the rat during short-term protein
      deficiency: responsiveness of the liver to partial hepatectomy.

PMID- 4358228
TI  - Letter: Minimal pressure neuropathy.

PMID- 4358227
TI  - Changes in serum pre-beta-lipoprotein following the feeding of sucrose. A
      preliminary trial in physically active and inactive young male students.

PMID- 4358226
TI  - Nucleic acid and polyamine synthesis in the rat during short-term protein
      deficiency: responsiveness of the bone marrow and liver to blood loss.

PMID- 4358229
TI  - Alpha-thalassaemia in an Australian family.

PMID- 4358230
TI  - Wilms' tumour: increasing hopes for survival.

PMID- 4358231
TI  - [Franz Volhard--the red and pale high pressure in the modern viewpoint. 1].

PMID- 4358233
TI  - Glycolytic enzyme activity of cells infected with adenovirus types 5 and 12.

PMID- 4358234
TI  - Changes in phospholipid composition of Micrococcus lysodeikticus during growth.

PMID- 4358232
TI  - Studies on the mode of action of dibromopropamidine.

PMID- 4358236
TI  - Transfemoral catheter embolization: a method of treatment of glomus jugulare
      tumors.

PMID- 4358235
TI  - [Progress in the diagnosis and therapy of bronchial carcinoma. Clinical results
      in 2579 cases].

PMID- 4358237
TI  - [Late results of plastic surgery on the pelvo-ureteral junction].

PMID- 4358238
TI  - Viremia during parainfluenza type 3 virus infection of hamsters.

PMID- 4358239
TI  - Further observations on the attachment of carbohydrate to lipoproteins by rat
      liver Golgi membranes.

PMID- 4358240
TI  - Antagonism of morphine analgesia by adenine, adenosine, and adenine nucleotides.

PMID- 4358241
TI  - Enancement of uptake of Simian virus 40 by nuclei of permissive cells.

PMID- 4358242
TI  - The calcium-independent stimulation of thymic lymphoblast DNA synthesis by low
      cyclic GMP concentrations.

PMID- 4358243
TI  - Hepatis B virus antigen development in cultured human hepatocytes.

PMID- 4358244
TI  - Simplified method for isolation of cytomegalovirus and demonstration of frequent
      viremia in renal transplant patients.

PMID- 4358245
TI  - The antitumor effect of interferon in lymphocyte- and macrophage-depressed mice.

PMID- 4358247
TI  - A simple automates fluorometric method for the determination of 2,3
      diphosphoglycerate in blood.

PMID- 4358246
TI  - Sucrose feeding in man. Effects of substrate incorporation into hepatic
      triglycerides and phosphoglycerides in vitro and on removal of intravenous fat in
      patients with hyperlipoproteinemia.

PMID- 4358248
TI  - Ectopic adrenocorticotropin syndrome with prostatic carcinoma.

PMID- 4358250
TI  - [Disseminated occlusions of coronary arteries, aortic arch arteries and lower
      limb arteries during primary hyperlipoproteinemia type II].

PMID- 4358249
TI  - [Case of cystinosis in a 10-year-old girl].

PMID- 4358251
TI  - [A case report of a rare localisation of diabetic neuropathy (author's transl)].

PMID- 4358252
TI  - [Paranephritic abscess--caused by an appendiceal carcinoma].

PMID- 4358253
TI  - The influence of exogenous substrates on the breakdown of alcohol.

PMID- 4358254
TI  - Molecular forms of glucose-6-phosphate dehydrogenase in liver diseases.

PMID- 4358256
TI  - Hidroadenoma of the vulva.

PMID- 4358255
TI  - Hepatic and adrenocortical function during cyclophosphamide stoss therapy.

PMID- 4358257
TI  - Virion polypeptides and structure of SV40.

PMID- 4358258
TI  - Preparation of equine infectious anemia virus antigen for immunodiffusion test.

PMID- 4358260
TI  - Multiple immobilized enzyme reactors: determination of pyruvate and
      phosphoenolpyruvate concentrations using immobilized lactate dehydrogenase and
      pyruvate kinase.

PMID- 4358259
TI  - Production of equine infectious anemia antigen in a persistently infected cell
      line.

PMID- 4358261
TI  - [Has the prognosis of Wilms tumor become more favourable?].

PMID- 4358263
TI  - Electrophoretic studies on three variants of Mengo encephalomyelitis virus.

PMID- 4358262
TI  - Structural characteristics of hydrated glycerol-and sphingo-lipids. A spin label
      study.

PMID- 4358264
TI  - Synthesis and acid hydrolysis of monophosphate and pyrophosphate esters of
      phytanol and phytol.

PMID- 4358265
TI  - Determination of bone age and recording of minor skeletal hand anomalies in
      normal children.

PMID- 4358266
TI  - [Laryngeal localizations of Abrikossof's tumor].

PMID- 4358267
TI  - [Role of bronchography and bronchoscopy in pulmonary adenomatosis].

PMID- 4358268
TI  - Susceptibility of herpesviruses to three nucleoside analogues and their
      combinations and enhancement of the antiviral effect of acid pH.

PMID- 4358270
TI  - Effects of cyclic 3',5'-AMP and related compounds on catecholamine-induced
      contraction of isolated guinea-pig vas deferens.

PMID- 4358271
TI  - Relaxing action of synthetic antispasmodics on the intestinal smooth muscle of
      guinea pig.

PMID- 4358272
TI  - Possibilities for drug development based on the cyclic AMP system.

PMID- 4358269
TI  - Ionic dependence of adrenal steroidogenesis and ACTH-induced changes in the
      membrane potential of adrenocortical cells.
AB  - 1. The effects of changes of ionic environment upon corticosteroid production by
      rabbit adrenal glands have been investigated in vitro using a superfusion
      technique and on-line steroid analysis by an automated fluorescence method. In
      some experiments micro-electrode recordings of adrenocortical transmembrane
      potentials were made concomitantly with measurement of steroid output.2.
      Adrenocorticotrophic hormone (ACTH), 10 m-u./ml., induced a sevenfold increase in
      corticosteroid production rate in normal Krebs solution.3. The steroidogenic
      response to ACTH was not impaired after omission of [K](o) for 1 hr but was
      inhibited following exposure to K(+)-free medium for 3 hr. Increase of [K](o)
      tenfold to 47 mM increased the basal but not the ACTH-stimulated output of
      corticosteroid whereas raising [K](o) twentyfold to 94 mM enhanced both the basal
      and ACTH-stimulated steroid production rate. In K(+)-free solution the
      adrenocortical cells hyperpolarized from - 67 to - 86 mV; subsequently on
      addition of ACTH they depolarized. Reintroduction of K(+) restored the membrane
      potential.4. Omission of Ca(2+) partially depolarized the cells but only affected
      the steroidogenic response to ACTH in the presence of EDTA. A threefold increase
      of [Ca](o), to 7.68 mM, had no effect on either membrane potentials or steroid
      formation, but increasing [Ca](o) tenfold to 25.6 mM partially blocked ACTH
      action. Increasing [Mg](o) twentyfold to 22.6 mM had little effect on ACTH
      stimulated corticosteroid output and Sr 2.56 mM, in substitution for Ca(2+),
      supported ACTH action, but La, 0.25 mM, completely blocked the steroidogenic
      effect of ACTH.5. Replacement of NaCl, 118 mM by choline chloride, 118 mM, was
      without effect on ACTH-induced steroidogenesis, whereas LiCl, 118 mM, reduced it
      by 50%. NaF, 1 and 10 mM, inhibited ACTH-induced steroidogenesis by approximately
      60%.6. Nupercaine, 10(-4)M, inhibited the steroid response to ACTH with no effect
      upon membrane potentials: increasing the nupercaine concentration to 10(-3)M
      inhibited the steroid response and depolarized the cells. Ouabain, 10(-5)M,
      induced complete depolarization and suppression of the steroidogenic response to
      ACTH.7. Action-potential-like changes in membrane potential appeared in cells
      exposed to ACTH in a K(+)-free medium. The amplitude of the action potentials
      ranged from 10 to 60 mV according to cell, with a frequency up to 36/min; the
      frequency tended to increase with time. Tetrodotoxin, 10(-6) g/ml., did not
      inhibit ACTH-induced action potentials in K(+)-free medium.8. These observations
      are discussed in relation to the ionic requirements for the steroidogenic action
      of ACTH. The results further emphasize the dissociation of membrane polarization
      and the secretion of steroid. The mechanism of output of steroid hormone from the
      adrenocortical cell may thus differ fundamentally from the secretory mechanisms
      in other, particle-storing cells.

PMID- 4358273
TI  - Metabolic pathways involved in the oxidation of isopropanol into acetone by the
      intact rat.

PMID- 4358274
TI  - [Study of the action of a coronary dilator agent: (isoamyloxy-3 (trimethoxy-3,4,5
      benzoyloxy)-propyl)-4 tetrahydro-oxazine-1,4 hydrochloride (amoproxan) on the
      metabolism of adenylic derivatives].

PMID- 4358275
TI  - [Suppression of paradoxical sleep with clomipramine].

PMID- 4358276
TI  - [Severe myelopathy, peripheral neuropathy and optic neuritis appearing during
      treatment with chloroiodoquin (clioquinol)].

PMID- 4358277
TI  - [Notes on neuropathies appearing during treatments with clioquinol].

PMID- 4358278
TI  - [Adenoma papillae mammae. An important differential diagnosis].

PMID- 4358279
TI  - [Medicinal treatment planning in primary trigeminal neuralgia].

PMID- 4358280
TI  - Hormonal control of bone cell function.

PMID- 4358281
TI  - Physiological significance of the vitamin D-dependent calcium-binding protein.

PMID- 4358283
TI  - [Ultrastructure of adenohypophyseal cells secreting ACTH in rats].

PMID- 4358282
TI  - [Ultrahistochemical studies of the nuclear inclusion bodies in juvenile
      nasopharyngeal fibromas (2nd report) (author's transl)].

PMID- 4358284
TI  - Electron microscopic-immunocytochemical localization of adrenocorticotropin and
      melanocyte stimulating hormone in the pars intermedia cells of rats and mice.

PMID- 4358285
TI  - [Corticosteroid regulation of hematopoiesis in fishes].

PMID- 4358286
TI  - Light and electron microscopy of the early response of Escherichia coli to a
      6beta-amidinopenicillanic acid (FL 1060).

PMID- 4358287
TI  - Disintegration of single cells in suspension. Isolation of rabbit
      polymorphonuclear leucocyte granules.

PMID- 4358288
TI  - Microphotometry for determining the reaction rate of O2 and CO with red blood
      cells in the chorioallantoic capillary.

PMID- 4358289
TI  - The nephelometric and membrane filtration technique applied to serum lipoprotein
      investigation.

PMID- 4358290
TI  - Biological significance of serum lipoproteins.

PMID- 4358291
TI  - Ultracentrifugation of human lipoproteins.

PMID- 4358293
TI  - The metabolism of LDL.

PMID- 4358292
TI  - Origin and fate of lipoproteins.

PMID- 4358294
TI  - The intravenous fat tolerance test with intralipid in various types of
      hyperlipidaemias and comparison between metabolism of intralipid and VLDL.

PMID- 4358295
TI  - The biogenesis and metabolism of steroids in the human placenta of 9--14 weeks in
      vitro.

PMID- 4358297
TI  - A study of some bradykinin potentiating peptides derived from plasma proteins.

PMID- 4358296
TI  - The effects of catecholamines on isolated perfused coronary arteries in the dog.

PMID- 4358298
TI  - The pharmacology of dibenzofuran and terphenyl derivatives of DMAE and
      hemicholinium-3.

PMID- 4358299
TI  - [Androblastomas of the ovaries induced by penetrating radiation].

PMID- 4358300
TI  - [Clear-cell hidradenoma].

PMID- 4358301
TI  - Fine structure of phagocytic cells in the chiton, Liolophura gaimardi.

PMID- 4358302
TI  - Macrophage activation in mice infected with ectromelia or lymphocytic
      choriomeningitis viruses.

PMID- 4358303
TI  - Replication of a cell-culture-modified infectious laryngotracheitis virus in
      experimentally infected chickens.

PMID- 4358305
TI  - Protection of chickens against Marek's disease virus JM-V strain with statolon
      and exogenous interferon.

PMID- 4358304
TI  - An avian adenovirus associated with respiratory disease.

PMID- 4358306
TI  - Chronologic study of the T-virus in chicks. I. Development of lesions.

PMID- 4358307
TI  - Chronologic study of the T-virus in chicks. II. Development of hematologic
      changes.

PMID- 4358309
TI  - [Purification and properties of isoenzymes of adenylate kinase].

PMID- 4358310
TI  - [Insulin].

PMID- 4358308
TI  - Effect of social stress and steroids on antibody production.

PMID- 4358311
TI  - [Progesterone-receptor].

PMID- 4358312
TI  - The use of silica gel for human calcitonin isolation in some thyroid diseases.

PMID- 4358313
TI  - The effect of cyclazocine on the cardiovascular responses to pressor and
      depressor amines in the rat.

PMID- 4358315
TI  - Dictyostelium discoideum aggregation fields as excitable media.

PMID- 4358314
TI  - Serum and tissue dopamine-beta-hydroxylase activity in hypophysectomized rats.

PMID- 4358316
TI  - [Abnormal behavior caused by methylxanthines: a study of experimental Lesch
      nyhman syndrome].

PMID- 4358317
TI  - [Isolated deficiency of anterior pituitary hormone].

PMID- 4358318
TI  - [Testicular feminization].

PMID- 4358319
TI  - [Anomalies of proteolytic enzymes and clinical manifestations].

PMID- 4358320
TI  - [Iodide-perchlorate discharge test: a new method for the diagnosis of disorders
      of iodine organification of the thyroid].

PMID- 4358321
TI  - [Disseminated shadows with special reference to alveolar lesions--differential
      diagnosis and significance of special diagnostic procedures].

PMID- 4358322
TI  - [Simultaneous laparoscopic and percutaneous cholangiography in cholangioma].

PMID- 4358323
TI  - [Familial t (22q Dq) translocation and free trisomy 21 in offspring].

PMID- 4358325
TI  - [Experience with excretory pancreography in endocrine diseases].

PMID- 4358324
TI  - [Primary malignant tumors of the liver in children. Apropos of 11 cases].

PMID- 4358326
TI  - [Age pecularities of the hypothalamic regulation of the hypophyseo-adrenal system
      in rats].

PMID- 4358327
TI  - [Electrophysiological analysis of myoneural synaptic transmission in rats with
      apparent alloxan diabetes].

PMID- 4358329
TI  - [Localisation by immunofluorescence of secretions related to thyreotropins,
      gonadotropins and corticotropins in axolotl pituitary(Ambystoma mexicanum, Shaw
      (author's transl)].

PMID- 4358328
TI  - [Living with an ileostomy].

PMID- 4358331
TI  - The effect of hyperactivity on synaptic transmission. Experiments in Blatta
      orientalis.

PMID- 4358330
TI  - [Detection of corticotropic and melanotropic cells in the hypophysis of the frog,
      Rana temporaria in the course of the development (author's transl)].

PMID- 4358332
TI  - Adenosine metabolism: properties of dog heart microsomal 5'-nucleotidase.

PMID- 4358333
TI  - Viral isolation rates during summer from children with acute upper respiratory
      tract disease and healthy children.

PMID- 4358334
TI  - Outbreak of a nosocomial infection with a strain of Proteus rettgeri resistant to
      many antimicrobials.

PMID- 4358335
TI  - Massive intrapulmonary venoarterial shunting in alveolar cell carcinoma. A case
      report.

PMID- 4358336
TI  - Recovery from severe cytomegalovirus pneumonia in a renal transplant patient.

PMID- 4358337
TI  - Guidelines for work for patients with tuberculosis.

PMID- 4358338
TI  - Effects of 2-N-(p-chlorobenzoyl)-N-(2-hydroxyethyl)aminomethyl-3-methyl
      norbornane on ganglionic transmission and response to acetylcholine and
      pilocarpine.

PMID- 4358339
TI  - Effects of essential phospholipids (EPL) on experimental cobalt-induced
      cardiomyopathy.

PMID- 4358340
TI  - [Human sleep in an unusual sleeping situation. Polygraphic records using placebos
      and a barbiturate-free sedative].

PMID- 4358341
TI  - [Antiviral activity of components of Echinacea purpurea].

PMID- 4358342
TI  - The synergistic action of antifertility compounds in the male rat.

PMID- 4358343
TI  - Aflatoxin inhibition of rat liver mitochondria.

PMID- 4358344
TI  - ACTH, glucagon and gastrin production by a pancreatic islet cell carcinoma and
      its treatment.

PMID- 4358347
TI  - Decreased vasoconstrictor response to angiotensin II in the presence of vascular
      stenosis.

PMID- 4358345
TI  - Interaction between secretion of the gonadotrophins, prolactin, growth hormone,
      thyrotrophin and corticosteroids in man: the effects of LH FSH-RH, TRH and
      hypoglycaemia alone and in combination.

PMID- 4358346
TI  - An improved isolation method and new composition data for Forssman hapten from
      sheep erythrocytes.

PMID- 4358348
TI  - The inhibition by ouabain of phospholipid turnover in the myocardium of the
      rabbit.

PMID- 4358349
TI  - Protein fractions from mouse salivary glands affecting epithelial cells in organ
      culture.
AB  - 1. Extracts of male mouse submaxillary gland have been fractionated on G 150
      Sephadex and DEAE cellulose.2. A number of the protein fractions obtained appear
      to cause proliferation of epithelial cells in organ cultures of rat tissues.3.
      All fractions active in organ culture possess proteolytic enzyme activity.4. The
      proteolytic enzymes trypsin, pronase and collagenase produce epithelial
      disorganization in organ culture.5. The organ culture effect is reduced in the
      presence of proteolytic enzyme inhibitors and abolished by pretreatment of
      proteins with diisopropylfluorophosphonate.6. The presence of mitotic inhibitors
      does not reduce the organ culture effect.7. The effect is not associated with an
      increase in the DNA content of tissue explants.8. No evidence has been found for
      the existence, in mouse salivary glands, of a specific growth factor acting on
      epithelial cells.

PMID- 4358350
TI  - Proceedings: Excitatory and inhibitory monosynaptic actions mediated by a
      serotonin containing neurone in Aplysia californica.

PMID- 4358352
TI  - The effect of tetanic and post-tetanic potentiation on facilitation of
      transmitter release at the frog neuromuscular junction.
AB  - 1. End-plate potentials (e.p.p.s) were recorded from frog neuromuscular junctions
      blocked with high Mg and/or low Ca.2. Estimates of f(t), the facilitation
      contributed by each impulse, were obtained during and following repetitive
      stimulation from the incremental change in e.p.p. amplitudes following step
      changes in the stimulation rate during the conditioning and testing trains.3.
      Estimates of f(t) increased during the conditioning stimulation and returned to
      control in the post-tetanic period. This increase in f(t) was proportional to the
      magnitude of tetanic or post-tetanic potentiation (PTP) present.4. These results
      are described by: [Formula: see text] where h(t)/h(c) is the e.p.p. amplitude at
      time t expressed in terms of the control, P(t) is potentiation, F(t) is
      facilitation and 1 is the base level of transmitter release. Thus, potentiation
      has a multiplicative (gain) effect on facilitation and the base level of
      transmitter release.5. PTP was present immediately following the conditioning
      train. However, if depression occurred during the conditioning train, PTP
      developed after a delay.6. It is suggested that facilitation and potentiation
      represent increases in two independent factors which act jointly to increase the
      probability of transmitter release.

PMID- 4358351
TI  - The effect of repetitive stimulation on facilitation of transmitter release at
      the frog neuromuscular junction.
AB  - 1. End-plate potentials (e.p.p.s) were recorded from frog neuromuscular junctions
      blocked with high Mg and/or low Ca to characterize the processes underlying
      increased transmitter release during repetitive stimulation.2. There was a
      progressive increase in the amplitude of successive e.p.p.s during repetitive
      stimulation. Increasing the frequency or duration of stimulation increased this
      facilitation of e.p.p. amplitudes. Facilitation is defined as the fractional
      increase in amplitude of a test e.p.p. over a control.3. By assuming that each
      impulse in a train contributes an identical increment of facilitation that sums
      linearly with the facilitation contributed by the previous impulses, estimates of
      the facilitation contributed by a single impulse, f(t), were made from the
      incremental increase in e.p.p. amplitudes during repetitive stimulation. The
      average value of f(t) contributed by the first impulse in the train during
      stimulation at 20/sec is given by f(t) = 0.8 e(-t/50) + 0.12 e (-t/300) + 0.025
      e(-t/3000),where t is in msec. The first two terms in this equation were
      independent of the stimulation rate used to determine f(t) while the coefficient
      of the third term was a function of the stimulation rate, decreasing 2 to 3 times
      when the stimulation rate was decreased from 20/sec to 1/sec.4. This linear
      facilitation model predicted growth of e.p.p. amplitudes during the first several
      hundred msec of repetitive stimulation. Thereafter, e.p.p. amplitudes were
      typically facilitated more than predicted by the linear model.5. Several new
      methods are presented which can be used to obtain estimates of the magnitude and
      time course of facilitation contributed by specific impulses during repetitive
      stimulation.6. It is found that the value of short-term f(t) in the tested range
      of 25-300 msec progressively increases during repetitive stimulation while its
      time course of decay remains unchanged. After 9 sec of stimulation at 20/sec, the
      short-term f(t) increased to 1.4 times control.7. The increase in short-term f(t)
      was independent of whether it was determined from a step increase or decrease in
      total facilitation, excluding the possibility that the observed increase in short
      term f(t) resulted from a change in the rate of decay of facilitation.8. It is
      suggested with supporting data from the following paper (Magleby, 1973) that each
      impulse contributes two types of facilitation that are responsible for the growth
      of e.p.p.s during repetitive stimulation: a short-term facilitation with linear
      summation properties described by the first two terms in the expression in
      paragraph 3 and a long-term cumulative facilitation approximated by the third
      term. The long-term facilitation is expressed as an increase in both the short
      term facilitation and in the base level of transmitter release. The relative
      contribution of these two expressions of the long-term facilitation to the third
      term is a function of the stimulation rate and is given by the ratio of
      facilitation to the base level of transmitter release.

PMID- 4358354
TI  - Proceedings: Increased drinking in dogs during congestive heart failure.

PMID- 4358353
TI  - Proceedings: Ultrastructural changes at the synapse associated with depression of
      synaptic transmission in rat superior cervical ganglion after injury of post
      ganglionic axons.

PMID- 4358355
TI  - Proceedings: The upper limit of 'autoregulation' of cerebral blood flow in the
      baboon.

PMID- 4358356
TI  - Proceedings: Presynaptic inhibition and the depressant actions of GABA and
      glycine in the feline cuneate nucleus: changes related to electrographic seizure
      activity.

PMID- 4358357
TI  - Proceedings: Periodicities in ventilation in new-born infants.

PMID- 4358358
TI  - Proceedings: Renin and angiotensin II of extrarenal origin in the plasma of
      female rabbits.

PMID- 4358359
TI  - Proceedings: Prostaglandin E1 synthesis by phagocytosing rabbit polymorphonuclear
      leucocytes: its inhibition by indomethacin and its role in chemotaxis.

PMID- 4358360
TI  - Optical diffraction on tilting series of paracrystalline intranuclear inclusions
      of dog liver parenchymal cells.

PMID- 4358361
TI  - Fine structure of spermiogenesis in scorpions from the family Vejovidae.

PMID- 4358362
TI  - Diagnosis of glycogen storage disease type I by serum immunodiffusion.

PMID- 4358363
TI  - Carcinogenicity of inhaled plutonium-238 in the rat.

PMID- 4358365
TI  - Kinetics of the renin system. The basis for determination of the different
      components of the system.

PMID- 4358364
TI  - Functional interpretation of lymphography according to contrast medium
      persistence in the lymph nodes.

PMID- 4358366
TI  - Organization of glycolysis: oscillatory and stationary control.

PMID- 4358368
TI  - Regulation of gene expression by cyclic AMP in Escherichia coli.

PMID- 4358367
TI  - Mitochondrial-cytosolic interactions in cardiac tissue: role of the malate
      aspartate cycle in the removal of glycolytic NADH from the cytosol.

PMID- 4358369
TI  - Rate control by insulin and its mechanism.

PMID- 4358370
TI  - Enzyme conformation and control.

PMID- 4358372
TI  - Frequency of renal intraendothelial microtubular inclusions in kidney
      transplants. An electron microscopy study.

PMID- 4358371
TI  - Search for BK and SV40 virus reactivation in renal transplant recipients.

PMID- 4358373
TI  - Studies on the tumor target cell destruction by in vitro sensitized lymphocytes.

PMID- 4358374
TI  - [Effect of microsome fractions on glycolysis in skeletal muscles in normal and
      dystrophic rabbits].

PMID- 4358377
TI  - [Therapy of organic hyperinsulinism].

PMID- 4358375
TI  - Immunobiology of genitourinary tumors.

PMID- 4358376
TI  - Ultrastructure of experimental brain gliomas in mice.

PMID- 4358379
TI  - [The role of Herpes virus hominis 2 in the genesis of cervical carcinoma].

PMID- 4358378
TI  - [Clinical picture of trophoblast tumors].

PMID- 4358380
TI  - A comparative study on the seed proteins of induced mutants of the pea.

PMID- 4358381
TI  - The cytopyge of Ciliata. II. Microphotographical documentation of the defecation
      in Prorodon teres.

PMID- 4358382
TI  - The cytopyge of Ciliata. 3. Microphotographical documentation of the defecation
      in Blepharisma ovata.

PMID- 4358384
TI  - Increased cellular reaction to damage caused by angiotensin in arterioles of
      normal recipient rats after transfer of lymphocytes from hypertensive rats.

PMID- 4358383
TI  - The effect of cyclic AMP on the erythropoiesis in mice(NMRI).

PMID- 4358386
TI  - Role of the renin-system in normo- and hypertension. Effect of angiotensin
      inhibitor (1-sar-8-ala-angiotensin II) on the blood pressure of conscious or
      anaesthetized normal, nephrectomized and renal hypertensive rats.

PMID- 4358385
TI  - Cause of the prolonged pressor action of renin in nephrectomized rats. Elucidated
      by means of anti-angiotensin II and of angiotensin-inhibitor (1-sar-8-ala
      angiotensin II).

PMID- 4358387
TI  - On the side-effects of contrast media for myelography. A histological examination
      of the spinal cord, nerve roots and meninges after experimental myelography with
      iodophendylate and methiodal.

PMID- 4358388
TI  - Rapid marked increase in plasma renin in rats treated with inhibitors of the
      renin system. Effects of 1-sar-8-ala-angiotensin II and of a synthetic converting
      enzyme inhibitor (nonapeptide, SQ 20.881) on normal and adrenalectomized rats.

PMID- 4358389
TI  - Experiences with depot neuroleptics in an after-care department.

PMID- 4358390
TI  - Protein deprivation in primates. I. Nonpregnant adult rhesus monkeys.

PMID- 4358391
TI  - Lipid metabolism and experimental atherosclerosis in baboons: influence of
      cholesterol-free, semi-synthetic diets.

PMID- 4358392
TI  - Electron microscopic observations on human glioblastomas and astrocytomas
      maintained in organ culture systems.
AB  - The fine structure of four glioblastomas and two cerebellar astrocytomas
      maintained in organ culture systems up to 137 days and 43 days, respectively,
      using either a three-dimensional sponge foam matrix technic or a Millipore filter
      platform technic, is described and compared. The cells of both tumor types showed
      increased astrocytic differentiation, characterized by a progressive increase in
      glial filaments associated with an increase in free ribosomes and granular
      endoplasmic reticulum. A progressive increase in basement membrane material,
      presumably originating from explanted endothelial cells or pericytes, was also
      found in both tumor types and was often associated with increased numbers of
      collagen fibrils. Astrocytic tumor cell processes frequently preserved their
      contact with this basement membrane material. Microvascular fenestrations or gaps
      in endothelial cells were not identified. These electron microscopic features
      appear to correspond to the early stages of perivascular sclerosis previously
      noted by light microscopy in gliomas maintained in organ culture systems and are
      presumably related to the progressive obliteration of the functional
      microvasculature.

PMID- 4358393
TI  - Salmonella typhimurium hisG46 (R-Utrecht): possible use in screening mutagens and
      carcinogens.
AB  - Salmonella typhimurium LT2 hisG46 becomes a more sensitive strain for assaying
      mutagens and carcinogens when it carries the resistance transfer factor R
      Utrecht.

PMID- 4358394
TI  - Spiradenoma. Histochemical and electron microscopic study.

PMID- 4358395
TI  - Vitamin E treatment of epidermolysis bullosa. Changes in tissue collagenase
      levels.

PMID- 4358396
TI  - Letter: Intertriginous xanthomas.

PMID- 4358397
TI  - A difference in the breakdown of phosphatidylinositol in normal and SV40
      transformed mouse fibroblasts.

PMID- 4358398
TI  - Separation and comparison of primary structures of three formylmethionine tRNAs
      from E. coli K-12 MO.

PMID- 4358399
TI  - The valence of copper and the role of superoxide in the D-galactose oxidase
      catalyzed reaction.

PMID- 4358400
TI  - Electron paramagnetic resonance studies of iron-sulfur centers in mitochondria
      prepared from three Morris hepatomas with different growth rates.

PMID- 4358401
TI  - The effects of some cations and anions on spin labeled cytoplasmic membranes of
      Bacillus subtilis.

PMID- 4358402
TI  - Cyclic changes in levels of cyclic AMP and cyclic GMP in frog myocardium during
      the cardiac cycle.

PMID- 4358403
TI  - Altered nuclear RNA transport associated with carcinogen intoxication in rats.

PMID- 4358404
TI  - Adrenocorticotropic hormone and dibutryl adenosine cyclic monophosphate-mediated
      Ca2+ uptake by rat adrenal glands.

PMID- 4358405
TI  - The effect of glucose ingestion on basal and induced enzyme levels in rat
      tissues.

PMID- 4358406
TI  - The delta-aminolevulinic acid synthetase activity and the effect of exogenous
      delta-aminolevulinate on the synthesis of cytochrome c in the thoracic muscles of
      the tobacco horn worm during adult development.

PMID- 4358407
TI  - A bromine compound isolated from human cerebrospinal fluid.

PMID- 4358408
TI  - Variation of proteins, enzyme markers and gangliosides in myelin subfractions.

PMID- 4358409
TI  - Effects of infusions of catecholamines, angiotensin, vasopressin and histamine on
      hepatic blood volume in the anaesthetized cat.
AB  - 1. Hepatic volume was recorded by a plethysmographic technique in cats
      anaesthetized with pentobarbitone; the hepatic artery and portal vein remained
      intact. Dose-response curves were obtained for intravenous infusions of
      adrenaline, noradrenaline, angiotensin, vasopressin and histamine.2. Adrenaline
      and noradrenaline decreased hepatic blood volume and did not differ significantly
      in potency. Up to 40% of the hepatic blood volume was expelled by doses within
      the range secreted by the adrenal medullae.3. Isoprenaline, infused into the
      hepatic artery, had no significant effect on hepatic blood volume in doses which
      caused maximal vasodilatation of the hepatic arterial bed. Relaxation of hepatic
      capacitance vessels mediated by beta-adrenoceptors did not occur.4. Angiotensin
      infusions in doses previously shown to cause intestinal and splenic
      vasoconstriction, decreased hepatic blood volume and on a molar or microgramme
      basis, angiotensin was the most potent of the agents tested. Doses within the
      probable physiological range of endogenous production decreased hepatic blood
      volume by up to 20%. The responses were not significantly different when the
      hepatic nerves were intact or sectioned.5. Vasopressin infusions produced only
      small decreases in hepatic blood volume. Doses within the range secreted by the
      posterior pituitary which constrict the intestinal and splenic resistance
      vessels, did not decrease hepatic blood volume by more than 10%.6. Histamine
      produced no change in hepatic blood volume in doses which readily produce outflow
      block in dogs. Either the specific hepatic venous smooth muscle involved in
      outflow block is absent in the cat or it has no histamine receptors.7. After the
      rapid change in hepatic blood volume at the onset of the infusion, hepatic volume
      remained steady for the duration of each infusion. There was no evidence that
      these agents caused net transsinusoidal fluid movements.

PMID- 4358410
TI  - Selective inhibition of angiotensin pressor responses in the pithed rat by
      tetraethylthiuram disulphide (disulfiram) and sodium diethyldithiocarbamate
      (DDC).
AB  - 1. Pressor responses to sympathetic outflow stimulation, noradrenaline and
      angiotensin have been recorded in pithed rats.2. Disulfiram (50 mg/kg) and sodium
      diethyldithiocarbamate (DDC) (5-100 mg/kg) both caused an initial increase in the
      pressor response to all three procedures followed by a selective inhibition of
      the angiotensin responses.3. Penicillamine (1-100 mg/kg) and ascorbic acid (1-500
      mg/kg) increased the pressor responses to all three procedures without any
      subsequent blocking action.4. Reserpine (5 mg/kg daily for 3 days) abolished
      responses to sympathetic outflow stimulation but did not impair angiotensin or
      noradrenaline responses.5. In reserpinized rats, the initial enhancement of
      angiotensin responses after disulfiram and sodium diethyldithiocarbamate was
      absent or reduced and the onset of the subsequent block was accelerated.6.
      Possible mechanisms for the angiotensin-blocking action of disulfiram and sodium
      diethyldithiocarbamate are discussed.

PMID- 4358412
TI  - Proceedings: Alterations in the sleep-wakefulness cycle in rats after
      administration of (-)-LSD or BOL-148: a comparison with (+)-LSD.

PMID- 4358411
TI  - Some aspects of the inhibition of the action of antidiuretic hormone by lithium
      ions in the rat kidney and bladder of the toad Bufo marinus.
AB  - 1. The effect of intravenous infusions of various ions on the antidiuretic action
      of antidiuretic hormone has been studied in rats.2. Lithium (13 mmol/l.)
      reversibly inhibits the antidiuretic responses. Similar concentrations of
      potassium, rubidium, strontium, magnesium, choline and calcium do not. Lithium
      has a similar effect on the antidiuretic activity of oxytocin.3. The inhibition
      is not simply related to blood nor whole body lithium concentrations.4. Lithium
      (2 mmol/l.) in contact with the serosal surface also inhibits the transport of
      water facilitated by either 0.5 U/l. antidiuretic hormone or 1.1 mmol/l. cyclic
      adenosine monophosphate in the isolated toad bladder.5. Choline (2 mmol/l.) on
      the serosal surface also inhibits the transport of water facilitated by
      vasopressin in the toad bladder.

PMID- 4358413
TI  - Proceedings: Active factors in the venom duct of Conus californicus.

PMID- 4358414
TI  - Proceedings: Concentrations of the oxime 2-hydroxyiminomethyl pyridinium methyl
      methane sulphonate (P2S) after intramuscular injections in humans.

PMID- 4358415
TI  - Proceedings: Tissue cyanide concentrations and cytochrome oxidase in experimental
      cyanide poisoning.

PMID- 4358416
TI  - Proceedings: New dialysis technique for the continuous measurement of the
      concentration of vasoactive hormones.

PMID- 4358417
TI  - The modern ankle-foot orthoses (AFO's).

PMID- 4358419
TI  - Human pancreatic islet tumor cells maintained in vitro.

PMID- 4358418
TI  - Editorial: Role of the kidney in the metabolism of calciferol (vitamin D).

PMID- 4358420
TI  - [Adenoma of the nipple, a clinical and morphological review (author's transl)].

PMID- 4358421
TI  - [Bilateral adenoma of nipple (author's transl)].

PMID- 4358422
TI  - Inhibition of glucose-induced insulin secretion in trypsin-treated islets of
      Langerhans.

PMID- 4358423
TI  - Effect of diabetes and insulin on the rat heart adenyl cyclase, cyclic AMP
      phosphodiesterase and cyclic AMP.

PMID- 4358424
TI  - Plasma ACTH in the adrenalectomized rat.

PMID- 4358425
TI  - Serum parathyroid hormone concentrations in vitamin D deficiency rickets of
      infancy: effects of intravenous calcium and vitamin D.

PMID- 4358427
TI  - The histiocytic infiltrates of the skin.

PMID- 4358426
TI  - Melanotic progonoma of the brain.

PMID- 4358428
TI  - Postnatal cytomegalovirus hepatitis. An autopsy and liver biopsy study.

PMID- 4358429
TI  - Inhibition of cell growth in the G1 phase by adenosine 3', 5'-cyclic
      monophosphate.
AB  - Incorporation of tritiated thymidine into acid-precipitable material was used to
      measure the rate of DNA synthesis in secondary cultures of human diploid
      fibroblasts. Confluent cultures of human diploid fibroblasts, which are
      synchronized in the G(1) phase due to contact inhibition, were released from
      growth inhibition either by the addition of fresh medium to the cultures or by
      trypsinization and replating at nonconfluent densities. Either treatment resulted
      in a synchronous wave of DNA synthesis beginning 10-15 h after treatment and
      peaking at 20-25 h. In confluent cultures stimulated by fresh medium, either the
      addition of 0.25 mM N(6), O(2)-dibutyryl-adenosine 3',5'-cyclic monophosphate (db
      cAMP) to the medium in the interval 4-8 h after stimulation or the replacement of
      the fresh medium in that same 4 h interval with the depleted medium present on
      the cells for the 2 day period before stimulation delayed the synchronous onset
      of DNA synthesis in the cultures by about 4 h. In nonconfluent cultures freshly
      seeded from trypsinized confluent cultures, this same depleted medium obtained
      after a 2 day incubation of fresh medium on confluent cultures is shown to
      support the progress of the cells into S phase; however, the addition of 0.25 mM
      db-cAMP to the medium 3(1/2) h after replating still partially prevented the
      initiation of DNA synthesis in the cultures. The results are discussed in terms
      of the role of serum and cAMP in the control of cell growth in fibroblast
      cultures.

PMID- 4358431
TI  - Adrenocorticotropin. 45. Synthesis and steroidogenic activity of (1
      alanine)adrenocorticotropin-(1-20)-amide, (1-D-alanine)adrenocorticotropin-(1-20)
      amide, and (1-14C)alanine)adrenocorticotropin-(1-20)-amide.

PMID- 4358430
TI  - Cytochemistry of Golgi fractions prepared from rat liver.
AB  - Cytochemical tests for several marker enzymes were applied to liver tissue and to
      the three Golgi fractions (GF(1), GF(2), GF(3)) separated by the procedure of
      Ehrenreich et al. from liver homogenates of alcohol-treated rats. 5'-Nucleotidase
      (AMPase) reaction product was found in all three fractions but in different
      locations: It occurred along the inside of the membrane of VLDL-filled vacuoles
      in GF(1) and GF(2), and along the outside of the cisternal membranes in GF(3). In
      the latter it was restricted to the dilated cisternal rims and was absent from
      the cisternal centers. The AMPase activity found in the fractions by biochemical
      assay is therefore indigenous to Golgi components and is not due to contamination
      by plasma membrane. Acid phosphatase (AcPase) reaction product was detected
      within lysosomal contaminants in GF(1) and within many VLDL-filled vacuoles in
      GF(1) and GF(2), indicating that AcPase activity is due not only to contaminating
      lysosomes, but also to enzyme indigenous to Golgi secretory vacuoles. G-6-Pase
      reaction product was present in GF(3) and within contaminating endoplasmic
      reticulum fragments, but not in other fractions. Thiamine pyrophosphatase
      (TPPase) was localized to some of the VLDL-filled vacuoles and cisternae in GF(1)
      and GF(2), and was not found in the cisternae in GF(3). The results demonstrate
      the usefulness of cytochemical methods in monitoring the fractionation procedure:
      They have (a) allowed a reliable identification of contaminants, (b) made
      possible a distinction between indigenous and contaminating activities, and (c)
      shown, primarily by the results of the TPPase test, that the procedure achieves a
      meaningful subfractionation of Golgi elements, with GF(1) and GF(3), representing
      primarily trans-Golgi elements from the secretory Golgi face, and GF(3)
      consisting largely of cis-Golgi components from the opposite face.

PMID- 4358432
TI  - Angiotensin-like and antagonistic activities of N-terminal modified (8
      leucine)angiotensin II peptides.

PMID- 4358433
TI  - Synthesis and anti-deoxyribonucleic acid virus activity of certain 9-beta-D
      arabinofuranosyl-2-substituted adenine derivatives.

PMID- 4358434
TI  - Propagation of both parental mitochondrial DNAs in rat-human and mouse-human
      hybrid cells.

PMID- 4358435
TI  - Inhibition of adrenergic vasoconstriction by quinidine.

PMID- 4358436
TI  - Angiotensin analogs: the influence of sarcosine substituted in position 1.

PMID- 4358437
TI  - Renin release and ketamine-induced cardiovascular stimulation in the rat.

PMID- 4358438
TI  - Effect of certain halogenated hydrocarbon insecticides on cyclic adenosine 3',5'
      monophosphate-3H formation by rat kidney cortex.

PMID- 4358440
TI  - The fluid state of lecithin bilayers.

PMID- 4358439
TI  - Lipid-protein and lipid-lipid interactions in cytochrome oxidase model membranes.

PMID- 4358442
TI  - Rhodopsin-lipid interactions.

PMID- 4358441
TI  - Synaptic vesicles: structure of chromaffin granule membranes.

PMID- 4358443
TI  - The effect of cyclic AMP on membrane permeability.

PMID- 4358444
TI  - Adenylate cyclase and cyclic AMP phosphodiesterase of normal and Rous sarcoma
      virus transformed chicken embryo fibroblasts.

PMID- 4358445
TI  - Red cell aggregation by macromolecules: roles of surface adsorption and
      electrostatic repulsion.

PMID- 4358446
TI  - New developments in pharmacology of vitamin D.

PMID- 4358447
TI  - Inapparent congenital cytomegalovirus infection with elevated cord IgM levels.
      Casual relation with auditory and mental deficiency.

PMID- 4358448
TI  - Host defenses against viral disease.

PMID- 4358449
TI  - Editorial: Subtle effects of perinatal infection.

PMID- 4358450
TI  - The clinical value of the magnification technique in cerebral angiography.

PMID- 4358451
TI  - Vincristine therapy in malignant glioma recurrencies.

PMID- 4358452
TI  - Increased activity of adenine phosphoribosyltransferase in erythrocytes of normal
      newborn infants.

PMID- 4358453
TI  - [Synthesis of antiproteolytic efficent arylcarbonyl-aralkylcarbonyl- and
      arylsulfonic acid esters of amidinophenols].

PMID- 4358454
TI  - Marital group therapy in the treatment of alcoholism.

PMID- 4358455
TI  - Ethanol consumption and enzyme activities in Sinclair miniature pigs.

PMID- 4358456
TI  - Antibodies to Epstein-Barr virus at the ages of 6 to 23 months in children with
      congenital heart disease.

PMID- 4358457
TI  - Serologic studies of infections in patients with hematologic malignancy.

PMID- 4358458
TI  - Serotypes and antibiotic susceptibility of Escherichia coli in non-enteric
      infections of children.

PMID- 4358459
TI  - Inhibition by castration of aflatoxin-induced hepatoma in carbon tetrachloride
      treated rats.

PMID- 4358460
TI  - The cardiotoxic effects of pressurized aerosol isoproterenol in the dog.

PMID- 4358462
TI  - [Glucose-6-phosphatase activity of the liver in pregnant rats, fetuses and
      placentas following glucose loading and estrogen administration].

PMID- 4358461
TI  - [A transitory, perinatal system of subependymal cells in the cerebral ventricles
      of the rat (author's transl)].

PMID- 4358464
TI  - [Comparative studies of 3 methods of skeletal age determination].

PMID- 4358465
TI  - [Changes of the ultrastructure of human tumours by transfer into laboratory
      animals. II. Mycosis fungoides with mycoplasma-like bodies (author's transl)].

PMID- 4358463
TI  - Hepatoma--nature's model tumor. A review.

PMID- 4358466
TI  - The bone cell system: form and function.

PMID- 4358467
TI  - Tumor doubling time and survival of men with bronchogenic carcinoma.

PMID- 4358468
TI  - Fulminant lymphoma mimicking pneumocystis carinii pneumonia.

PMID- 4358469
TI  - Structural requirements for substrates and inhibitors of angiotensin I-converting
      enzyme in vivo and vitro.

PMID- 4358470
TI  - Sensitization of the adrenal cortex to angiotensin II in sodium-deplete man.

PMID- 4358471
TI  - The pathophysiology of renin.

PMID- 4358472
TI  - [Serum lipoproteins and lipids in patients with hepatitis (author's transl)].

PMID- 4358473
TI  - Effects of neuroleptanesthesia on endocrine function in man.

PMID- 4358474
TI  - Hexachlorophene revisited.

PMID- 4358476
TI  - Sophisticated simplification for medical services.

PMID- 4358475
TI  - The surgical management of axillary hyperhidrosis.

PMID- 4358477
TI  - History of the library trust fund.

PMID- 4358478
TI  - Helen Brenton Pryor, M.D.--pediatrician. (1898-1972).

PMID- 4358479
TI  - Letter: Women to the rescue.

PMID- 4358480
TI  - A study of hepatitis-associated antigen in hospital patients.

PMID- 4358481
TI  - Tumor rejection and immunotherapy studies with simian virus 40-induced tumors.

PMID- 4358482
TI  - Pentose shunt enzyme activities in non-inflamed attached gingiva of dogs.

PMID- 4358483
TI  - The lung--an endocrine organ?

PMID- 4358484
TI  - Diabetic foot.

PMID- 4358485
TI  - [Excision of a segment of the abdominal aorta invaded by retroperitoneal tumor].

PMID- 4358486
TI  - [Giant fibroadenoma of the breast].

PMID- 4358488
TI  - Persistent cloaca with no urethral, genital, or anal openings.

PMID- 4358487
TI  - [Editorial: Alcohol and the heart].

PMID- 4358489
TI  - Perinatal infections and epidemiology of anencephaly and spina bifida.

PMID- 4358490
TI  - [Tumors of the nervous system].

PMID- 4358491
TI  - [Salivary gland tumors].

PMID- 4358493
TI  - [Renal cancer].

PMID- 4358492
TI  - [Breast cancer].

PMID- 4358494
TI  - [Malignant testicular tumors].

PMID- 4358495
TI  - [Malignant trophoblastic tumors].

PMID- 4358496
TI  - [Malignant tumors in childhood].

PMID- 4358497
TI  - [Malignant mixed tumor of the larynx].

PMID- 4358498
TI  - [Respiratory distress syndrome in premature and newborn infants. 2. Therapy of
      respiratory distress syndrome].

PMID- 4358499
TI  - [Pathomorphological studies on piglets experimentally infected with a vaccine
      strain of Herpes suum virus].

PMID- 4358500
TI  - Skin hypersensitivity to parainfluenza-3 virus in cattle.

PMID- 4358501
TI  - [Studies on rabbits and sheep concerning the immunogenic effect of various types
      of prepared toxins of Clostridium welchii (perfringens) type A with and without
      complete Freund's adjuvant].

PMID- 4358502
TI  - The aetiology of perceptive deafness. A clinico-pathological and anatomical study
      of temporal bones and brain structures.

PMID- 4358504
TI  - Making referrals is everybody's business.

PMID- 4358503
TI  - [Controlled study of mucolytic agent associated with kinesitherapy in obstructive
      lung diseases (author's transl)].

PMID- 4358505
TI  - Dynamic response of the intact canine adrenal to infused ACTH.

PMID- 4358506
TI  - Systems analysis of arterial pressure regulation and hypertension.

PMID- 4358508
TI  - [Mechanism of insulin action].

PMID- 4358509
TI  - [Synthetic ACTH therapy].

PMID- 4358507
TI  - Influence of binding on the pharmacologic activity of antibiotics.

PMID- 4358510
TI  - The utilization of fluorescent microscopy in routine chromosome analysis.

PMID- 4358511
TI  - Contraceptive usage among teenagers.

PMID- 4358512
TI  - Suicide in children and adolescents.

PMID- 4358513
TI  - Nepotism: paradoxical liberation.

PMID- 4358514
TI  - The management of emotional crises by medical practitioners.

PMID- 4358515
TI  - Metatarsalgic neurogenica. A definitive clinical syndrome.

PMID- 4358516
TI  - [Catecholamine and the heart].

PMID- 4358517
TI  - [Experiments in reproducing necrotic enteritis in broiler chickens (author's
      transl)].

PMID- 4358518
TI  - Possible aetiological factors of calciphylaxis in pigs.

PMID- 4358519
TI  - The quantity and estrogenic activity of F-2 toxin produced on different
      substrates.

PMID- 4358520
TI  - [Viruses and mammary cancer. A survey (author's transl)].

PMID- 4358521
TI  - [Neonatal canine herpesvirus infection (author's transl)].

PMID- 4358522
TI  - [Pathophysiology and therapy of diabetes].

PMID- 4358524
TI  - [Study of the biological activity of the vitamin D3 conversion product in bone
      tissue].

PMID- 4358523
TI  - [Advances in pulmonology. Lung--an organ of important metabolic processes].

PMID- 4358525
TI  - Experimental study on combined therapy with anticancer drugs and urokinase.

PMID- 4358527
TI  - Parotid benign giant mixed tumor of forty-two years duration with malignant
      transformation.

PMID- 4358526
TI  - [Botkin's viral hepatitis and the problem of the Australia antigen].

PMID- 4358528
TI  - [Anaplastic lung carcinoma in dogs].

PMID- 4358529
TI  - Neonatal calf diarrhea. Electron microscopy of intestines infected with a
      reovirus-like agent.

PMID- 4358530
TI  - Hepatoma in a mangabey (Cercocebus atys).

PMID- 4358531
TI  - Pneumoconiosis in the captive New Zealand kiwi.

PMID- 4358532
TI  - [Properties and serological grouping of 26 strains of bovine enteroviruses
      isolated in Algeria].

PMID- 4358533
TI  - Breast carcinoma with late recurrence (cytological type 3).

PMID- 4358534
TI  - Epstein-Barr virus infection in the neonatal period and in childhood.
AB  - In an attempt to detect and characterize congenital, neonatal and early childhood
      EBV infections, a prospective sero-epidemiological study was undertaken in 112
      newborn infants and their mothers, 25 additional newborns undergoing exchange
      transfusion, 114 randomly selected hospitalized infants aged 0 to 3 years, and
      109 siblings and parents of these infants. Leukocyte culture was attempted in all
      the newborns and in 25 pre- and post-transfusion.The findings of EBV
      seroconversion in six patients without clearly apparent illness, infectious
      mononucleosis in only one case with significant EBV antibody rise, seroreversion
      in three cases in early childhood, higher newborn than maternal EBV antibody
      titres in three cases and the establishment of two permanent lymphoblastoid cell
      lines from newborns following exchange transfusion raise the possibility of
      abortive primary EBV infection in early life. Congenital or neonatal infections
      following exchange transfusions, however, could not be substantiated with
      certainty since the EBV antibodies did not persist at follow-up except possibly
      in two cases. Parenteral transmission of the EB virus by exchange transfusion at
      birth is probably prevented by the presence of EBV antibodies in either donor or
      recipient.

PMID- 4358536
TI  - Relationship of antigenicity of melanoma cells grown in 5-bromodeoxyuridine to
      reduced tumorigenicity.

PMID- 4358537
TI  - Polyadenylate-containing RNA of polyribosomes isolated from rat liver and Morris
      hepatoma 7800.

PMID- 4358535
TI  - Epstein-Barr virus infections.

PMID- 4358538
TI  - Ultrastructural comparison between the distribution of concanavalin A and wheat
      germ agglutinin cell surface receptors of normal and transformed hamster and rat
      cell lines.

PMID- 4358539
TI  - Comparison of surface material, cytoplasmic filaments, and intercellular
      junctions from untransformed and two mouse sarcoma virus-transformed cell lines.

PMID- 4358540
TI  - Enhancement of adenovirus transformation by treatment of hamster embryo cells
      with diverse chemical carcinogens.

PMID- 4358541
TI  - Dietary enhancement of nitrosamine carcinogenesis.

PMID- 4358543
TI  - [Herpes genitalis in women with special reference to cytological changes
      (author's transl)].

PMID- 4358542
TI  - Rapid two-dimensional immunoelectrophoresis of human serum proteins.

PMID- 4358544
TI  - A light and electron microscopic study in serial sections of dystrophic
      extraocular muscle fibers.

PMID- 4358545
TI  - Human adrenal tumors and hyperplasias in vitro: a bridge between morphology and
      function.

PMID- 4358546
TI  - Oxytyrosinase.

PMID- 4358547
TI  - Relation between the ribosomal sites involved in initiation and elongation of
      polypeptide chains. Evidence for two guanosine triphosphatase sites.

PMID- 4358548
TI  - Isolation and properties of a ribosome-bound factor required for ppGpp and ppGpp
      synthesis in Escherichia coli.

PMID- 4358549
TI  - Regulatory properties of perchlorate-extracted succinate dehydrogenase.

PMID- 4358551
TI  - Early photoinduced enzymes of photoinduced carotenogenesis in a Mycobacterium
      species.

PMID- 4358550
TI  - Amino acid sequence of cytochrome c3 from Desulfovibrio vulgaris.

PMID- 4358552
TI  - Hormone receptors. 3. Properties of glucagon-binding proteins isolated from liver
      plasma membranes.

PMID- 4358553
TI  - Regulated in vitro synthesis of Escherichia coli tryptophan operon messenger
      ribonucleic acid and enzymes.

PMID- 4358554
TI  - Self-association and allosteric properties of glutamine-dependent carbamyl
      phosphate synthetase. Reversible dissociation to monomeric species.

PMID- 4358555
TI  - Reversible dissociation of the monomer of glutamine-dependent carbamyl phosphate
      synthetase into catalytically active heavy and light subunits.

PMID- 4358556
TI  - Effects of ouabain on catecholamine-stimulated sodium transport in turkey
      erythrocytes.

PMID- 4358557
TI  - Adenosine 3':5'-monophosphate-dependent protein kinase from yeast.

PMID- 4358558
TI  - Characterization of the serum high density lipoprotein and apolipoproteins of
      pink salmon.

PMID- 4358559
TI  - The structure of the abortive diphosphopyridine nucleotide-pyruvate-lactate
      dehydrogenase ternary complex as determined by proton magnetic resonance
      analysis.

PMID- 4358560
TI  - A proton relaxation rate study of the copper analog of Escherichia coli alkaline
      phosphatase.

PMID- 4358562
TI  - Angiotensin II receptors in bovine adrenal cortex. Modification of angiotensin II
      binding by guanyl nucleotides.

PMID- 4358561
TI  - Blocks in ganglioside synthesis in transformed hamster cells and their
      revertants.

PMID- 4358563
TI  - Presence of collagenase from Clostridium histolyticum in gingival sulcal debris
      of a primitive population.

PMID- 4358564
TI  - Evaluation of collagenase activity in the crevicular fluid of children.

PMID- 4358565
TI  - The nature of myelinated nerve fiber degeneration in dominantly inherited
      hypertrophic neuropathy.

PMID- 4358566
TI  - The role of cyclic AMP in mesenteric vasodilation.

PMID- 4358567
TI  - Involvement of alpha-receptors in clonidine-induced inhibition of transmitter
      release from central monoamine neurones.

PMID- 4358568
TI  - Dopaminergic denervation supersensitivity and dopamine stimulated adenyl cyclase
      activity.

PMID- 4358569
TI  - [Studies on animal and organ specificity of chlorphentermine induced
      morphological alterations (author's transl)].

PMID- 4358571
TI  - [Role of monoamines in the regulation of alertness. Neurophysiological and
      biochemical study].

PMID- 4358570
TI  - The influence of 1-(5-oxohexyl-)3.7-dimethylxanthine (BL 191) on the endocrine
      and exocrine pancreatic function in man during and following secretin and
      cholecystokinin-pancreozymin stimulation.

PMID- 4358573
TI  - [Sleep privation with eye movements using antidepressive agents].

PMID- 4358572
TI  - [Monoamines and the regulation of wakefulness. I. Contribution and biochemical
      interpretation of the polygraphic data].

PMID- 4358574
TI  - [Problem of catecholamine migration in the sympathetic neurons].

PMID- 4358575
TI  - [Correlations between chemical mediators (dopamine, serotonin, acetylcholine and
      gaba), muscular tone and rapidity of movement].

PMID- 4358577
TI  - Cyclic adenosine monophosphate: selective increase in caudate nucleus after
      administration of L-dopa.
AB  - Treatment with the dopamine precursor L-dopa produced a significant accumulation
      of adenosine 3',5'-monophosphate (cyclic AMP) in the caudate nucleus of the rat.
      In contrast, there was no change in the amount of cyclic AMP in the cerebellum.
      Accumulation of cyclic AMP in the caudate nucleus after administration of L-dopa
      was prevented by prior treatment with the decarboxylase inhibitor RO 4-4602.
      These observations and those in other laboratories support the assumption that
      dopamine formed from L-dopa selectively activates striatal adenylate cyclase. The
      in vivo activation of adenylate cyclase after treatment with L-dopa may be a
      useful model for studying neurological and psychiatric disorders that are thought
      to involve the dopaminergic system of the brain.

PMID- 4358576
TI  - Paradoxical increase in rate of catabolism of low-density lipoproteins after
      hepatectomy.
AB  - It has been suggested that the liver may be a major site for irreversible
      degradation of low-density lipoprotein (LDL). The disappearance of autologous
      (125)I-labeled LDL from plasma was compared in intact and in hepatectomized
      swine. Contrary to expectations, the rate of irreversible removal of LDL from
      plasma was increased rather then decreased by hepatectomy. These studies suggest
      that the liver is not a major site for LDL removal. We propose further that the
      liver (or some function requiring an intact liver) may affect the metabolism of
      LDL in a manner that prolongs its lifetime in the plasma compartment.

PMID- 4358578
TI  - Acute gastroenteritis associated with echovirus type 1.

PMID- 4358579
TI  - [Adenoma of the nipple: a histopathological report (author's transl)].

PMID- 4358580
TI  - Action of polymyxin B on bacterial membranes. 1. Binding to the O-antigenic
      lipopolysaccharide of Salmonella typhimurium.

PMID- 4358581
TI  - [Effect of lithium and thiocyanate ions on the metabolism of nucleic acids of
      Tetrahymena pyriformis, normal and neoplastic mammalian cells (author's transl)].

PMID- 4358582
TI  - The effect of 1-nitro-9-aminoacridine on respiration and glycolysis in Ehrlich
      ascites tumour cells.

PMID- 4358584
TI  - Preparative photochemical synthesis of isoguanosine ribo- and
      deoxyribonucleosides and nucleotides, and isoguanosine-3',5'-cyclic phosphate, a
      new cAMP analogue.

PMID- 4358583
TI  - Alkylation of cytidine-5'-phosphate: mechanisms of alkylation, influence of O'
      alkylation on susceptibility of pyrimidine nucleotides to some nucleolytic
      enzymes, and synthesis of 2'-O-alkyl polynucleotides.

PMID- 4358585
TI  - Manganese induced histochemical and histological alterations in gastrointestinal
      mucosa of guinea pigs.

PMID- 4358586
TI  - A correlation study between adrenal function and the duration of sustained ACTH
      treatments in the rat.

PMID- 4358587
TI  - The effect of ethanol on hemostatic properties of human blood platelets.

PMID- 4358589
TI  - The Child Mental Health Specialist: a new profession.

PMID- 4358588
TI  - Clinical manifestations of hepatoma. A review of 6 years' experience at a cancer
      hospital.

PMID- 4358590
TI  - Family structure, aftercare, and post-hospital adjustment.

PMID- 4358591
TI  - Quantitation of bovine papilloma virus and serum antibody by immunodiffusion.

PMID- 4358592
TI  - Mixed leukocyte culture test in dogs.

PMID- 4358593
TI  - The use of passive hemagglutination for the detection of bluetongue viral
      antibodies.

PMID- 4358594
TI  - Biological characteristics and viral susceptibility of a rat embryonic skin cell
      line (RESI).

PMID- 4358595
TI  - The politics of empiricism. Research recommendations of the Joint Commission on
      Mental Health of Children.

PMID- 4358596
TI  - Morphologic effects of minocycline on the cochlea of the guinea pig.

PMID- 4358598
TI  - Ultrastructural study of clostridial myositis.

PMID- 4358597
TI  - [Cranial nerve lesions in sinusitis. A case of sinus cavernosus-syndrome without
      sinus cavernosus-thrombosis (author's transl)].

PMID- 4358600
TI  - Improved purification and further characterization of Clostridium perfringens
      type A enterotoxin.

PMID- 4358599
TI  - Pituitary gland in patients with Hurler syndrome. Light and electron microscopic
      study.

PMID- 4358602
TI  - [On the treatment of hyperlipoproteinaemia type II with cholestyramine (author's
      transl)].

PMID- 4358601
TI  - Immunofluorescence of peritoneal phagocytes after infection in vivo with egg
      attenuated Chlamydia psittaci 6BC.

PMID- 4358603
TI  - [Intraneural hemorrhage in the peroneal  nerve during femoral neck fractures].

PMID- 4358604
TI  - Mode of action of N6-O2'-dibutyryl cyclic 3',5' AMP on fat cell metabolism.

PMID- 4358605
TI  - Antilipolytic action of tolbutamide in isolated fat cells of the rat.

PMID- 4358606
TI  - Induction of liver and lung tumours in rats by the simultaneous administration of
      sodium nitrite and morpholine.

PMID- 4358609
TI  - The structure of ferrocytochrome c at 2.45 A resolution.

PMID- 4358607
TI  - [Enzyme histochemical studies on the porcine testicular interstitial cells during
      postnatal development (author's transl].

PMID- 4358608
TI  - Human high density lipoprotein, apolipoprotein glutamine II. The immunochemical
      and lipid-binding properties of apolipoprotein glutamine II derivatives.

PMID- 4358610
TI  - Adenosine cyclic 3':5'-monophosphate-dependent protein kinase from rabbit
      erythrocytes. Purification and characterization of multiple forms.

PMID- 4358611
TI  - Hormonal control of glycogenolysis and gluconeogenesis in isolated rat liver
      cells.

PMID- 4358612
TI  - Mitochondrial assembly in respiration-deficient mutants of Saccharomyces
      cerevisiae. I. Effect of nuclear mutations on mitochondrial protein synthesis.

PMID- 4358614
TI  - Mitochondrial assembly in respiration-deficient mutants of Saccharomyces
      cerevisiae. 3. A nuclear mutant lacking mitochondrial adenosine triphosphatase.

PMID- 4358613
TI  - Mitochondrial assembly in respiration-deficient mutants of Saccharomyces
      cerevisiae. II. Effect of nuclear and extrachromosomal mutations on the formation
      of cytochrome c oxidase.

PMID- 4358615
TI  - Stoichiometry of adenosine triphosphate-driven proton translocation in bovine
      heart submitochondrial particles.

PMID- 4358616
TI  - Intracellular localization of enzymes of arginine metabolism in Neurospora.

PMID- 4358617
TI  - Protein hydration changes in the formation of the nicotinamide adenine
      dinucleotide complexes of glyceraldehyde 3-phosphate dehydrogenase of yeast. I.
      Buoyant densities, preferential hydrations, and fluorescence-quenching
      titrations.

PMID- 4358618
TI  - Protein hydration changes in the formation of the nicotinamide adenine
      dinucleotide complexes of glyceraldehyde 3-phosphate dehydrogenase of yeast. II.
      The spin lattice relaxation of solvent water protons.

PMID- 4358619
TI  - Sheep liver 6-phosphogluconate dehydrogenase. Inhibition by nucleoside phosphates
      and by other metabolic intermediates.

PMID- 4358620
TI  - Regulation of steroidogenesis by adrenocorticotropic hormone in isolated adrenal
      cells of rats.

PMID- 4358621
TI  - Chemical and enzymatic evidence for the participation of a 2-carboxy-3
      ketoribitol-1,5-diphosphate intermediate in the carboxylation of ribulose 1,5
      diphosphate.

PMID- 4358622
TI  - Site-directed spin labeling of the mitochondrial membrane. Synthesis and
      utilization of the adenosine triphosphatase inhibitor (N-(2, 2, 6, 6-tetramethyl
      piperidyl-1-oxyl)-N'-(cyclohexyl)-carbodiimide).

PMID- 4358623
TI  - A general method of tritium labeling utilizing microwave discharge activation of
      tritium gas. Methodology and application to biological compounds.

PMID- 4358624
TI  - Evidence for a dissociable glucagon binding site in a solubilized preparation of
      myocardial adenylate cyclase.

PMID- 4358625
TI  - The involvement of ribonuclease I, ribonuclease II, and polynucleotide
      phosphorylase in the degradation of stable ribonucleic acid during carbon
      starvation in Escherichia coli.

PMID- 4358626
TI  - Nicotinamide adenine dinucleotide-specific glyceraldehyde 3-phosphate
      dehydrogenase from Pisum sativum. Purification and characterization.

PMID- 4358627
TI  - Nicotinamide adenine dinucleotide-specific glyceraldehyde 3-phosphate
      dehydrogenase from Pisum sativum. Assay and steady state kinetics.

PMID- 4358628
TI  - Nicotinamide adenine dinucleotide-specific glyceraldehyde 3-phosphate
      dehydrogenase from Pisum sativum. Effect of nicotinamide adenine dinucleotide and
      related compounds on the enzyme-catalyzed arsenolysis of 1,3-diphosphoglyceric
      acid.

PMID- 4358629
TI  - The nucleotide sequence adjoining the CCA end of an Escherichia coli tyrosine
      transfer ribonucleic acid gene.

PMID- 4358630
TI  - The mechanism of action of adrenocroticotropic hormone. The role of mitochondrial
      cholesterol accumulation in the regulation of steroidogenesis.

PMID- 4358631
TI  - Angiotensinase activity of dipeptidyl aminopeptidase I (cathepsin C) of rat
      liver.

PMID- 4358632
TI  - Effect of cyclic adenosine 3':5'-monophosphate on ribosomal protein
      phosphorylation in reticulocytes.

PMID- 4358633
TI  - Estimation of the fructose 1,6-diphosphatase-phosphofructokinase substrate cycle
      and its relationship to gluconeogenesis in rat liver in vivo.

PMID- 4358634
TI  - Purification and properties of phosphoribosyl pyrophosphate synthetase from rat
      liver.

PMID- 4358635
TI  - Stability and regulation of phosphoribosyl pyrophosphate synthetase from rat
      liver.

PMID- 4358636
TI  - Purification of adenohypophyseal plasma membranes and properties of associated
      adenylate cyclase.

PMID- 4358638
TI  - Nonenzymatic formation of guanosine 3':5'-monophosphate from guanosine
      triphosphate.

PMID- 4358639
TI  - Fractionation of 34 S ribonucleic acid subunits from oncornaviruses on
      polyuridylate-sepharose columns.

PMID- 4358637
TI  - Phosphorylation of adenohypophyseal plasma membranes and properties of associated
      protein kinase.

PMID- 4358640
TI  - Properties of follicle-stimulating hormone-receptor interactions. Specific
      binding of human follicle-stimulating hormone to rat testes.

PMID- 4358641
TI  - Evidence for interdependent action of glucagon and nucleotides on the hepatic
      adenylate cyclase system.

PMID- 4358642
TI  - A gonadotropin-responsive adrenocortical adenoma.

PMID- 4358643
TI  - TSH stimulation of 32P incorporation into phospholipids of thyroids from patients
      with Graves' disease.

PMID- 4358644
TI  - Control of refractory fasting hypoglycemia in a patient with suspected insulinoma
      with diphenylhydantoin.

PMID- 4358645
TI  - Estrogen receptor concentration in normal and pathological human uterine tissues.

PMID- 4358646
TI  - Endocrine function in an anencephalic infant.

PMID- 4358647
TI  - Cyclic AMP accumulation and steroidogenesis in the human corpus luteum: effect of
      gonadotropins and prostaglandins.

PMID- 4358648
TI  - Rhesus leukocyte-associated herpesvirus. I. Isolation and characterization of a
      new herpesvirus recovered from rhesus monkey leukocytes.

PMID- 4358649
TI  - Rhesus leukocyte-associated herpesvirus. II. Natural and experimental infection.

PMID- 4358650
TI  - Evaluation of cholinesterase-restoring agents in the treatment of tetanus in man.

PMID- 4358651
TI  - Effect of adenine arabinoside on severe Herpesvirus hominis infections in man.

PMID- 4358652
TI  - Viruses causing common respiratory infections in man. 3. Respiratory syncytial
      viruses and coronaviruses.

PMID- 4358654
TI  - Treatment of herpesvirus encephalitis with iododeoxyuridine.

PMID- 4358653
TI  - Ecthyma gangrenosum produced by Aeromonas hydrophilia.

PMID- 4358655
TI  - Letter: Bilateral eventration of the diaphragm in a neonate with congenital
      cytomegalic inclusion disease.

PMID- 4358657
TI  - Iodide goiter following lymphography.

PMID- 4358656
TI  - Iatrogenic Cushing's disease in a boy after misdiagnosis of salt-losing
      virilizing adrenal hyperplasia: impaired metyrapone response with failure of
      catch-up growth.

PMID- 4358658
TI  - [Clinical aspects and diagnosis of enterovirus infection].

PMID- 4358660
TI  - Hepatitis B antigen: removal from protein solutions in a recognizable form by an
      insoluble lipophilic matrix of silicic acid.

PMID- 4358661
TI  - Enzymatic hydrolysis of nucleoside phosphoramidates.

PMID- 4358662
TI  - Chemical structure and absolute configuration of a juvenile hormone from
      grasshopper corpora allata in vitro.

PMID- 4358664
TI  - Fatty acid metabolism in denervated muscle of frog in vitro.

PMID- 4358663
TI  - Cholesterol in cerebrospinal fluid of brain tumor patients.

PMID- 4358666
TI  - Pharmacological interaction between cannabidiol and delta 9-tetrahydrocannabinol.

PMID- 4358665
TI  - Congenital cytomegalovirus infection: consecutive occurrence due to viruses with
      similar antigenic compositions.

PMID- 4358667
TI  - [Application of radioimmunoanalysis of angiotensin I to the determination of
      plasma renin activity in humans].

PMID- 4358669
TI  - Cyclic AMP and its relation to clinical chemistry.

PMID- 4358668
TI  - [Paget's carcinoma of the vulva].

PMID- 4358672
TI  - [Extended resection in lung cancer].

PMID- 4358671
TI  - Pretreatment classification and staging of bronchogenic carcinoma.

PMID- 4358670
TI  - Urinary cyclic AMP excretion in toxaemia of pregnancy.

PMID- 4358673
TI  - Comparative electron microscopic studies on Pseudomonas aeruginosa endotoxin.

PMID- 4358675
TI  - On the receptor of influenza viruses. 1. Artificial receptor for influenza virus.

PMID- 4358674
TI  - [Complexformation of dehydrogenases with coenzyme analogues and coenzyme
      fragments (author's transl)].

PMID- 4358677
TI  - [Status of the phosphatases in the peripheral blood elements in epilepsy].

PMID- 4358676
TI  - Ribonuclease present in myxoviruses.

PMID- 4358678
TI  - Sleep of distance runners.

PMID- 4358680
TI  - Creutzfeldt-Jakob disease: a histochemical study with microdensitometric assay of
      some enzymes.

PMID- 4358682
TI  - 90Y ferric hydroxide colloid.

PMID- 4358683
TI  - Retention of 90Y in patients with rheumatoid arthritis.

PMID- 4358679
TI  - Ultrastructural study of neuronal cytoplasmic inclusions produced by
      hypocholesterolemic drug, AY 9944.

PMID- 4358681
TI  - Chemistry of iron in biological systems.

PMID- 4358684
TI  - Early components of the averaged electroencephalic response to constant level
      clicks during rapid eye movement sleep.

PMID- 4358685
TI  - Acute localized amebic appendicitis: report of a case.

PMID- 4358686
TI  - [Embryonal nephroma in a dog].

PMID- 4358688
TI  - [Change in the fibrous nature of quartz dust].

PMID- 4358687
TI  - Diaminopurine-resistant mutants of cultured, diploid human fibroblasts.
AB  - Clones of cells resistant to 2,6-diaminopurine were detected in skin fibroblast
      cultures derived from 13 of 21 normal humans of both sexes from 17 unrelated
      families. Almost all of the cultures that yielded mutants were chosen for further
      study from among a total of 83 surveyed because they displayed a slight
      resistance to low concentrations of diaminopurine. The incidences of mutant
      colonies ranged between about 10(-5) and 10(-4) per cell surviving prior
      mutagenic treatment with MNNG. The incidences of spontaneous mutants were about
      10(-7) to 10(-5) in three unrelated cultures. Most independent mutants had
      distinctly reduced activity of adenine phosphoribosyltransferase but some had
      apparently normal amounts of activity. Two mutants from unrelated boys had little
      or no detectable enzyme activity and were unable to effectively use exogenous
      adenine for growth when purine biosynthesis was blocked with azaserine. Most
      mutants could utilize exogenous adenine, just as most azaguanine-resistant
      fibroblast mutants can utilize exogenous hypoxanthine, even when their
      hypoxanthine-guanine phosphoribosyltransferase activity is reduced. Diverse
      genetic changes conferred diaminopurine resistance but their specific natures are
      still undefined. Gross numerical or structural chromosome abnormalities were not
      observed in the mutants examined so far. Since at least one gene responsible for
      adenine phosphoribosyltransferase activity is on autosome No. 16 our results
      suggest that at least some of the cultures yielding mutants were heterozygous and
      that alleles conferring diaminopurine resistance may be frequent enough to
      comprise a polymorphism.

PMID- 4358689
TI  - Organizational history of HSMHA.

PMID- 4358690
TI  - The NIMH approach to evaluating the community mental health centers program.

PMID- 4358692
TI  - Electrotonic conduction in the optic nerves of planorbid snails.

PMID- 4358691
TI  - [Pathological anatomy of pulmonary arteries in pulmonary hypertension].

PMID- 4358693
TI  - Capacitation of epididymal spermatozoa in a medium with high K-Na ratio and
      cyclic AMP for the fertilization of rat eggs in vitro.

PMID- 4358694
TI  - Oestradiol-17beta: its influence on cyclic 3'5'-adenosine monophosphate
      phosphodiesterase and 5'-nucleotidase in the cervicovaginal epithelium of
      neonatal mice.

PMID- 4358695
TI  - [Determination of some hormones in women with simple glaucoma during menopause].

PMID- 4358696
TI  - [Cases of amebiasis in Massalinskyi district of Azerbaijan SSR].

PMID- 4358697
TI  - [Obtaining and storing angiotensin II antiserum that can be used in
      radioimmunoassay methods].

PMID- 4358699
TI  - [Experiences with conversion of a mental hospital ward to a therapeutic society].

PMID- 4358698
TI  - [After-care department with out-patient facilities and day and night hospital in
      a mental hospital. Experiences from the year 1971].

PMID- 4358700
TI  - Multilocular cysts of kidney.

PMID- 4358701
TI  - Plasma renin activity. Comparison of bioassay and radioimmunoassay techniques.

PMID- 4358703
TI  - Adrenalectomy and hypophysectomy for prostatic cancer.

PMID- 4358702
TI  - Renal cystography with triple-contrast material.

PMID- 4358704
TI  - [Defective particles in a virus population].

PMID- 4358705
TI  - [Morphological criteria for differentiation of mycoplasmas and oncornaviruses].

PMID- 4358706
TI  - [Strain differences in rhinoviruses according to the spectrum of susceptible cell
      cultures].

PMID- 4358707
TI  - [Characteristics of vesicular stomatitis virus persisting for a long time in L
      cell cultures].

PMID- 4358708
TI  - [Laboratory model for experimental study of the pathogenesis of parainfluenza
      infection].

PMID- 4358711
TI  - Alkaline and acid phosphatase activity in buffalo semen.

PMID- 4358709
TI  - [Study of sera from cattle in different farms of the Azerbaijan SSR for antibody
      to bovine adenoviruses types 1, 2 and 3 and to parainfluenza virus type 3].

PMID- 4358710
TI  - [Morphogenesis of type A oncornaviruses in dividing cells].

PMID- 4358712
TI  - Adeno, parainfluenza, RS, and corona viruses and Mycoplasma pneumoniae as
      etiologic agents of acute respiratory tract infections.

PMID- 4358713
TI  - Serological surveillance of respiratory viruses in healthy population of the
      Koszalin Province.

PMID- 4358714
TI  - Seroepidemiological studies on the occurrence of several respiratory viruses in
      the population of the Lublin province.

PMID- 4358715
TI  - Typhoid-paratyphoid (TAB) vaccine as interferon inducer in mice.

PMID- 4358716
TI  - The in vitro effect of cyclophosphamide on Col. MM virus replication and
      interferon production.

PMID- 4358718
TI  - Antiviral drugs in human therapy.

PMID- 4358719
TI  - Studies on antiviral activity of alpha-trihalogenomethylamines.

PMID- 4358717
TI  - Role of incomplete viruses and interferon in persistent infection of mouse cells
      with Sindbis virus.

PMID- 4358720
TI  - Latent virus infections in primary monkey kidney cultures.

PMID- 4358721
TI  - [Primary familial herpes infections].

PMID- 4358722
TI  - [Type 3 hyperlipoproteinemia].

PMID- 4358724
TI  - A comparative study of purine metabolism by human and pig erythrocytes in vitro.

PMID- 4358723
TI  - Kinin-converting aminopeptidase from human serum.

PMID- 4358726
TI  - [Sleep disorders and periodical respiration in obese persons].

PMID- 4358727
TI  - [Unusual clinical pictures in the course of an Arbovirus infection].

PMID- 4358725
TI  - Effects of adrenochrome and sodium perborate on isolated fat cell metabolism.

PMID- 4358728
TI  - Effects of chlorpromazine, thioridazine and haloperidol on adrenergic transmitter
      mechanisms in man.

PMID- 4358731
TI  - Distribution of 51Cr-labeled lymphoid cells in the lymph node draining the
      inoculated tumor in the rat.

PMID- 4358732
TI  - Type-C virus in cultured cells derived from normal and tumor cells of a rat.

PMID- 4358730
TI  - Synergistic effects of bis(3-methylsulfonyloxypropyl)-amine toluenesulfonate (864
      T) with 6-mercaptopurine and other antitumor agents.

PMID- 4358729
TI  - Comparative effect of vincristine and alkylating agent No. 864 on rat leukemia in
      relation to the distribution of drugs and leukemic cells.

PMID- 4358735
TI  - Surgical anatomy of the intraglandular portion of the facial nerve.

PMID- 4358734
TI  - Hepatoblastoma.

PMID- 4358733
TI  - [Clostridium perfringens in the process of the preparation and storage of meat
      loafs].

PMID- 4358736
TI  - Cytoplasmic and nuclear pyrimidine ribonucleotide pools in HeLa cells.

PMID- 4358738
TI  - Inactivation of poliovirus in water by ozonation.

PMID- 4358739
TI  - Trichinosis--the Maryland outbreak of 1970.

PMID- 4358737
TI  - Experiences with vulvar cancer.

PMID- 4358741
TI  - Isolation and purification of surface antigens from disrupted paramyxoviruses.

PMID- 4358740
TI  - [Influence of Bordetella pertussis on the lymphatic tissue of mice. 8. The
      influence of Bordetella pertussis on the primary and secondary immune potential
      of thymusless ("nude") mice (author's transl)].

PMID- 4358742
TI  - The influence of polymyxin B on virus-induced cytopathogenic effect.

PMID- 4358746
TI  - [Mutants of Anacystis nidulans with modified process of cell division].

PMID- 4358744
TI  - [High-molecular polyphosphates and enzymes of polyphosphate metabolism in the
      process of growth of an Escherichia coli culture].

PMID- 4358745
TI  - [Carbon dioxide assimilation by Hydrogenomas pantotropha Z-11].

PMID- 4358743
TI  - Mitochondrial DNA synthesis in Raji cells infected by herpes simplex virus or
      Epstein-Barr virus.

PMID- 4358747
TI  - [The organic psycho-syndrome in Wilson's disease (longterm follow-up with
      psychologic testing in 4 patients during d-penicillamin-therapy) (author's
      transl)].

PMID- 4358748
TI  - [Primary malignant embryonal tumors of the anterior mediastinum. Report of 2
      cases].

PMID- 4358751
TI  - Histochemical investigations into the lipid nature of the oil-droplet in the
      retinal twin-cones of Lebistes reticulatus (Peters). (With 5 figures).

PMID- 4358749
TI  - Recovery of the antibody-forming potential in cyclophosphamide-treated mice, with
      special reference to the influence of Bordetella pertussis.

PMID- 4358750
TI  - Neurotransmitting substances and endotoxin respone in relation to hepatic enzyme
      induction.

PMID- 4358752
TI  - Studies on RNA metabolism during lymphocyte activation.

PMID- 4358753
TI  - [The Bourneville-Pringle-Syndrome from an urological and radiological viewpoint
      (author's transl)].

PMID- 4358754
TI  - The effect of pattern movement on the impulse activity of the cervical connective
      of Drosophila melanogaster.

PMID- 4358755
TI  - [Stimulation of embryonic rat cells in culture by calf serum. VII. Decrease of
      intracellular cAMP level not caused by leakage of the nucleotide into the culture
      medium (author's transl)].

PMID- 4358756
TI  - Histochemical and fine structure observations of the intestinal epithelium of
      Trichuris suis (Nematoda: Trichuroidea).

PMID- 4358757
TI  - [Identification of merozoites of 4 cyst-forming Coccidia (Sarcocystis,
      Toxoplasma, Besnoitia, Frenkelia) by means of electron microscopy (author's
      transl].

PMID- 4358758
TI  - Embryogenesis of Calliphora erythrocephala. 3. Ultrastructure of the midgut
      epithelial cells during late embryonic development.

PMID- 4358759
TI  - The fine structure of the spermatozoon of Littornia (Gastropoda: Prosobranchia),
      with special reference to sperm motility.

PMID- 4358761
TI  - Ultrastructure of STH cells of the pars distalis of castrated male mice after
      hepatectomy.

PMID- 4358762
TI  - Ultrastructural studies of the commensal suctorian, Choanophrya infundibulifera
      Hartog. I. Tentacle structure, movement and feeding.

PMID- 4358760
TI  - CSF contacting axons and synapses in the lumen of the pineal organ.

PMID- 4358764
TI  - Structural connections between dense core vesicles in the central nervous system
      of Anodonta cygnea L. (Mollusca, Eulamellibranchia).

PMID- 4358763
TI  - Ultrastructural studies of the commensal suctorian, Choanophrya infundibulifera
      Hartog. II. Tentacle morphogenesis.

PMID- 4358765
TI  - Replication of swinepox virus in the skin of naturally infected pigs. Electron
      microscopic study.

PMID- 4358766
TI  - [Wholesomeness of high concentrations of free radicals in irradiated foods].

PMID- 4358767
TI  - Intracerebral hemorrhage as initial symptom of a brain tumor.

PMID- 4358768
TI  - A guide to bone scanning.

PMID- 4358769
TI  - Spectrophotometric determination of free silica.

PMID- 4358770
TI  - Home care after peripheral vascular surgery.

PMID- 4358772
TI  - [Clinical and ultrastructural observations in a case of juvenile amaurotic idiocy
      with protracted course (author's transl)].

PMID- 4358771
TI  - The histological classification of malignant lung tumors.

PMID- 4358773
TI  - [Ultrastructure of blood capillaries of spinal ganglia in normal conditions and
      in burns].

PMID- 4358775
TI  - [Modern treatment of syndactylia].

PMID- 4358776
TI  - Suppression of plasma ACTH levels with corticosteroids in Addison's disease.

PMID- 4358774
TI  - [Iron-containing inclusions in bone marrow plasma cells in hypoplastic anemia].

PMID- 4358777
TI  - Production of a corticotrophin-like intermediate lobe peptide and of
      corticotrophin by a bronchial carcinoid tumour.

PMID- 4358778
TI  - Plasma unconjugated and conjugated 17-hydroxycorticosteroids in different
      clinical disorders.

PMID- 4358779
TI  - ACTH and MSH assays and their clinical application.

PMID- 4358781
TI  - [Some aspects of the process of Enterovirus inactivation by chlorine].

PMID- 4358780
TI  - [Editorial: Free radicals and toxicology].

PMID- 4358782
TI  - Establishing an alcoholism treatment program in a community hospital.

PMID- 4358783
TI  - Human cerebral blood flow during sleep and waking.

PMID- 4358784
TI  - Studies on the circadian rhythm of phosphoenolpyruvate carboxykinase activity in
      rats. II. Effect of the autonomic nervous system on the rhythm in liver.

PMID- 4358785
TI  - Glyceraldehyde 3-phosphate dehydrogenase of Bacillus stearothermophilus. Kinetics
      and physicochemical studies.

PMID- 4358786
TI  - Interaction of yeast alcohol dehydrogenase with various substrates. I. Binding of
      coenzymes.

PMID- 4358787
TI  - [Inter and supra renal interruption of the inferior vena cava (beneath the
      hepatic veins)].

PMID- 4358789
TI  - [Wilms tumors in adults].

PMID- 4358788
TI  - Disseminated herpesvirus infection in a rhesus monkey (Macaca mulatta).

PMID- 4358791
TI  - [Synovial sarcoma].

PMID- 4358790
TI  - Cerebral lipids in experimental cyanide encephalopathy.

PMID- 4358792
TI  - [Role of angiography in the diagnosis of soft tissue tumors of the extremities].

PMID- 4358793
TI  - [The activating role of ACTH in the mechanism of equilibration of functions of
      the body].

PMID- 4358795
TI  - [Tumors of the parotid region].

PMID- 4358794
TI  - The differential capacity of a nerve channel.

PMID- 4358796
TI  - Response of specific skin hypersensitivity and haemagglutination inhibiting
      antibody after smallpox vaccination in human newborns and adults.

PMID- 4358798
TI  - [Benign lung tumor--x-ray].

PMID- 4358799
TI  - [Surgical treatment of benign lung tumors. Report of 108 surgical cases].

PMID- 4358797
TI  - [Benign lung tumors].

PMID- 4358800
TI  - [Proceedings: Case presentation of the 63rd Dermatological Evening in Wiesbaden].

PMID- 4358801
TI  - Effects of chronic alcohol abuse on the fatty acid composition of major lipids in
      the human brain. Hepatocerebral degeneration II.

PMID- 4358803
TI  - Cerebrospinal fluid cholesterol. Quantitative analysis of unesterified and
      esterified cholesterol and normal values in the cerebrospinal fluid.

PMID- 4358804
TI  - Correlation between hypothalamic serotonin content and adrenal function during
      acute stress. Effect of adrenal corticosteroids on hypothalamic serotonin
      content.

PMID- 4358807
TI  - [Nodular hidradenoma (apocrine cystadenoma) of the penis].

PMID- 4358802
TI  - [Phospholipid composition of different parts of the brain and electric organ of
      the electric ray Torpedo ocellata].

PMID- 4358806
TI  - [Verrucoid sebaceous nevus with neurological, ocular and osseous manifestations
      (Solomon's nevus)].

PMID- 4358808
TI  - [Functional morphology of the liver in peptic ulcer].

PMID- 4358805
TI  - Staphylococcus epidermidis isolated from bovine milk. Biochemical properties,
      phage sensitivity and pathogenicity for the udder.

PMID- 4358809
TI  - [Morphological changes in the liver in hereditary hemolytic jaundice].

PMID- 4358811
TI  - Biochemical and biophysical studies on cytochrome c oxidase. XI. Reaction with
      azide.

PMID- 4358810
TI  - The kinetic and redox potentiometric resolution of the carotenoid shifts in
      Rhodopseudomonas spheroides chromatophores: their relationship to electric field
      alterations in electron transport and energy coupling.

PMID- 4358813
TI  - A new cytochrome b-like pigment with a peak at 567 nm and a low redox potential
      in denitrifying bacteria.

PMID- 4358812
TI  - Mitochondrial metabolism in porphyric rat liver.

PMID- 4358814
TI  - Biochemical and biophysical studies on cytochrome c oxidase. XII. Kinetics of
      azide binding.

PMID- 4358815
TI  - A simple method for the purification of commercial neuraminidase preparations
      free from proteases.

PMID- 4358816
TI  - Studies on a pyrophosphatase and glucose-6-phosphatase from Aspergillus oryzae.

PMID- 4358817
TI  - Letter: Singlet oxygen decontaminating activity of erythrocuprein (superoxide
      dismutase).

PMID- 4358818
TI  - Conformational changes of aspartate aminotransferases in the region of Cys-45
      residue observed by means of spin label.

PMID- 4358819
TI  - Synthesis of glucose-6-phosphate by a I,3-diphosphoglycerate-glucose
      phosphotransferase activity of liver microsomes.

PMID- 4358820
TI  - Prednisolone for idiopathic (Bell's) facial palsy.

PMID- 4358821
TI  - Molecular properties of lactic dehydrogenase under the conditions of the
      enzymatic test. Sedimentation analysis and gel filtration in the microgram and
      nanogram range.

PMID- 4358822
TI  - Pathways for the oxidation of malate and reduced pyridine nucleotide by wheat
      mitochondria.

PMID- 4358824
TI  - [Circulation of adenoviruses in the wards of a respiratory department].

PMID- 4358823
TI  - Effect of temperature on the behavior of rat-liver mitochondria during
      centrifugation in a sucrose gradient.

PMID- 4358825
TI  - [Use of the electron paramagnetic resonance method in hygiene research].

PMID- 4358826
TI  - [Surgical treatment of precancerous conditions of the colon].

PMID- 4358827
TI  - [Lymphangiosarcoma, the brawny arm complication after mastectomy].

PMID- 4358828
TI  - [Clinical aspects and therapy of an extramammary, anal Paget's disease].

PMID- 4358829
TI  - [The problem of resection or enucleation of a pancreatic insulinoma].

PMID- 4358830
TI  - Effects of hypnotic induction and suggestions on nocturnal dreaming and thinking.

PMID- 4358831
TI  - Equine infectious anemia: a retrospective study of an epizootic.

PMID- 4358832
TI  - Combined (B- and T-lymphocyte) immunodeficiency: a fatal genetic disease in
      Arabian foals.

PMID- 4358833
TI  - Carotid baroreceptor modulation of diaphragm and abdominal muscle activity in the
      cat.

PMID- 4358834
TI  - Intranuclear rods and sheets in rat cochlear nucleus.

PMID- 4358835
TI  - The fine structure of freeze-fractured presynaptic membranes.

PMID- 4358836
TI  - Aggregations of filaments in Schwann cells of spinal roots of the normal rat.

PMID- 4358837
TI  - [Electron microscopic study of the processes of origination and formation of the
      integument in Cestoda as exemplified by Triaenophorus nodulosus].

PMID- 4358838
TI  - [Blood cholesterol and its distribution in the lipoproteins of patients with
      coronary atherosclerosis].

PMID- 4358839
TI  - Editorial: Analysis of congestive heart failure in terms of ventricular function
      curves.

PMID- 4358840
TI  - Alcohol and the blood.

PMID- 4358841
TI  - Respiratory characteristics of the cabbage butterfly during different stages of
      larval development.

PMID- 4358843
TI  - [Nursing care of chronic in-patients].

PMID- 4358842
TI  - Cytochrome c and evolution of the energy acquiring system.

PMID- 4358844
TI  - [Genetic functions  of the mitochondria].

PMID- 4358845
TI  - The effect of cyclic AMP and aminophylline on Limulus lateral eye retinular
      cells.

PMID- 4358847
TI  - [Clinical study of ucb 3983 in pediatric (author's transl)].

PMID- 4358848
TI  - Effect of renal pressor systems on vascular capacity during hemorrhage.

PMID- 4358846
TI  - [Diagnosis and treatment of the cylindromas of the otorhinolaryngologic organs].

PMID- 4358849
TI  - Characterization of smooth muscle receptors for angiotensin: studies with an
      antagonist.

PMID- 4358850
TI  - Metabolic effects of ACTH in the sheep.

PMID- 4358852
TI  - Hormonal and dietary adaptation of rat pancreatic hydrolases before and after
      weaning.

PMID- 4358851
TI  - Glucose metabolism in jejunal mucosa of fed, fasted, and streptozotocin-diabetic
      rats.

PMID- 4358853
TI  - Protocollagen proline hydroxylase activity in work-induced hypertrophy of rat
      muscle.

PMID- 4358855
TI  - Using cooperative extension programs for health education.

PMID- 4358854
TI  - Evidence for adrenocortical uptake of ACTH in vivo.

PMID- 4358857
TI  - Antibody to viruses affecting cattle in commercial tissue culture grade fetal
      calf serum.
AB  - Commercial fetal calf serum (FCS) for tissue culture use was tested for
      neutralizing activity against several viruses which affect cattle. Certain lots
      of FCS contained no neutralizing activity, whereas other lots contained
      neutralizing activity to several viruses. It was concluded that the neutralizing
      activity found in certain lots of sera was due to specific antibody and that its
      presence could be most easily explained by the contamination of the FCS with
      serum from postcolostral bovine serum. A nonantibody inhibitor to vesicular
      stomatitis virus was also found at low levels in most lots of serum. Because
      those sera which had antibody had antibody to several viruses, it was suggested
      that the use of the micro-serum neutralization test with a few bovine viruses
      which are widespread in the bovine population should be satisfactory to detect
      FCS which was contaminated with postcolostral bovine serum.

PMID- 4358856
TI  - Useful antiviral drugs.

PMID- 4358858
TI  - Use of stable, sensitized cells in indirect micro hemagglutination test for
      amebiasis.
AB  - Human "O" cells were fixed with pyruvic aldehyde, treated with tannic acid, and
      fixed with glutaraldehyde. The cells were sensitized with amoeba antigen and
      stored in a refrigerator. The sensitized cells were used periodically for the
      indirect hemagglutination test with a battery of sera from patients with
      intestinal amebiasis and confirmed and unconfirmed amebic liver abscess, and also
      from negative controls. The same battery was tested with cells sensitized with
      different batches of antigen and also with fresh sheep cells. None of the cells
      showed any reaction with negative control sera. The fixed cells remained
      sensitive and stable throughout the study. Reproducibility of the titers with the
      fixed cells within each day and from day to day was satisfactory. The titers with
      fixed human "O" cells were slightly lower than were the titers with fresh sheep
      cells. The advantages of using stable, sensitized cells are pointed out.

PMID- 4358859
TI  - Methods for visualization of enzymes in polyacrylamide gels.
AB  - White bands resulting from precipitation of dodecan-1-ol liberated by hydrolysis
      of sodium dodecyl sulfate and decan-5-ol released by hydrolysis of decan-5-yl
      sulfate produced zymograms of the primary and secondary alkylsulfatases from
      Pseudomonas C(12)B. Gas-liquid chromatographic analyses of ether extracts of the
      precipitate-containing segments of the zymograms confirmed the identity of the
      alcohols which were not discerned in extracts of segments of the gels other than
      those containing precipitates. beta-Galactosidase from Escherichia coli was
      marked on zymograms by the liberation of o-nitrophenol from o-nitrophenyl-beta-D
      galactoside, and arylsulfatase from Pseudomonas C(12)B was marked in gels by
      liberation of p-nitrophenol from p-nitrophenyl sulfate. Membrane-associated
      dissimilatory nitrate reductases from a nitrate respirer (Enterobacter aerogenes)
      and a denitrifier (Pseudomonas perfectomarinus) did not penetrate either 6.8 or
      3% polyacrylamide gel but were demonstrable at the top of the gels. In the
      membrane-bound state, formate served as electron donor for nitrate reductase from
      E. aerogenes, and reduced nicotinamide adenine dinucleotide (NADH) served as
      donor for nitrate reductase from P. perfectomarinus. Both enzymes reduced nitrate
      at the expense of reduced benzyl viologen as well. Assimilatory nitrate reductase
      from E. aerogenes moved easily into the 6.8% gels (R(f) = 0.43 under the
      conditions of these experiments). The reduced dye served as electron donor for
      the assimilatory reductase, but formate and NADH did not. Incubation of the
      membrane-associated nitrate reductases with 2% Triton X-100 solubilized the
      enzymes and removed the capacity of formate and NADH to serve as electron donors.
      Both retained the ability to reduce nitrate at the expense of reduced benzyl
      viologen. The solubilized dissimilatory reductase from E. aerogenes moved further
      in the gels (R(f) = 0.49) than the soluble assimilatory reductase; the
      solubilized dissimilatory reductase from the denitrifier, P. perfectomarinus,
      moved further in the gels (R(f) = 0.64) than either of the enzymes from E.
      aerogenes.

PMID- 4358861
TI  - Microtiter hemagglutination-inhibition test for the detection of
      encephalomyocarditis virus antibodies.
AB  - Several variables were found to affect the agglutination of sheep erythrocytes by
      encephalomyocarditis virus. A satisfactory and reliable microtiter
      hemagglutination-inhibition test is described.

PMID- 4358860
TI  - Detection of bacteremia with liquid media containing sodium polyanetholsulfonate.
AB  - Two liquid blood culture media, Tryptic soy broth (TSB) and Thiol broth,
      containing sodium polyanetholsulfonate were compared in 8,654 cultures.
      Pseudomonas and Corynebacterium (including Propionibacterium) were isolated
      significantly more frequently (P < 0.001) from TSB than from Thiol. Escherichia
      coli, Haemophilus, and Bacteroidaceae were isolated more frequently in TSB;
      however, the differences were not statistically significant. In no instance was
      Thiol superior to TSB in detecting bacteremia. In an additional 2,977 cultures,
      aerobic and anaerobic Vacutainer culture tubes with supplemented peptone broth
      were inoculated in parallel with TSB and Thiol. Significantly greater rates of
      detection (P < 0.01) in TSB or Thiol were noted with Pseudomonas, E. coli,
      Enterobacter, viridans, and group A streptococci, Bacteroidaceae, and
      staphylococci.

PMID- 4358864
TI  - A follow-up of monozygotic twins discordant for schizophrenia.

PMID- 4358867
TI  - Mallory bodies and giant mitochondria--two different structures in liver biopies
      from alcoholics.

PMID- 4358866
TI  - Intramitochondrial filamentous inclusions in chronic glomerulonephritis.

PMID- 4358865
TI  - Basal cell adenoma of the parotid gland.

PMID- 4358863
TI  - Evaluation and modifications of media for enumeration of Clostridium perfringens.
AB  - The suitability of the Shahidi-Ferguson perfringens, TSC (tryptose-sulfite
      cycloserine), and oleandomycin-polymyxin-sulfadiazine perfringens agars for
      presumptive enumeration of Clostridium perfringens was tested. Of these, the TSC
      agar was the most satisfactory. The TSC agar method was improved by eliminating
      the egg yolk and using pour plates. The modified method allowed quantitative
      recoveries of each of 71 C. perfringens strains tested and is recommended. For
      confirmation of C. perfringens, the nitrite test in nitrate motility agar was
      unreliable, particularly after storage of the medium for a few days. In contrast,
      positive nitrite reactions were obtained consistently when nitrate motility agar
      was supplemented with glycerol and galactose.

PMID- 4358862
TI  - Inactivation of encephalomyocarditis virus in aerosols: fate of virus protein and
      ribonucleic acid.
AB  - After aerosolization at relative humidities of 50% or lower, encephalomyocarditis
      virus is rapidly inactivated. In this process the protein coat of the virion is
      damaged. This appears as a loss of hemagglutination activity and loss of affinity
      for hemagglutination inhibiting antibodies. The ribonucleic acid of the virus
      retains its infectivity but it becomes susceptible to ribonuclease. It sediments
      in sucrose gradients when centrifuged at high speed with the same velocity as
      free infectious ribonucleic acid extracted with phenol from intact
      encephalomyocarditis virus.

PMID- 4358868
TI  - The mechanism of action of the respiratory inhibitor, antimycin.

PMID- 4358870
TI  - Odontodysplasia.

PMID- 4358869
TI  - The different cytochrome b components in the respiratory chain of animal
      mitochondria and their role in electron transport and energy conservation.

PMID- 4358871
TI  - Oral medicine for the dental practitioner. 4. Recurrent ulcers.

PMID- 4358872
TI  - [Classification and diet therapy of hyperlipemia].

PMID- 4358873
TI  - The separation of human B lymphocytes on a digestible immunoadsorbent column.

PMID- 4358875
TI  - Measurement of human red cell angiotensinase activity by angiotensin II
      radioimmunoassay.

PMID- 4358876
TI  - Phospholipids in the cytochrome oxidase reaction.

PMID- 4358877
TI  - Sulfhydryl groups of cytochrome oxidase.

PMID- 4358874
TI  - Operative and cytostatic treatment of germinal tumours of the testis.

PMID- 4358878
TI  - Effect of estrogens on the mast cell degranulating action of compound 48-80.

PMID- 4358879
TI  - Selective cytotoxicity of peritoneal leucocytes. A preliminary report.

PMID- 4358880
TI  - Some properties of a homocarnosine-carnosine synthetase isolated from rat brain.

PMID- 4358881
TI  - Electrophoretic characterization of leucine, glucosamine- and fucose-labelled
      proteins rapidly transported in frog sciatic nerve.

PMID- 4358882
TI  - Chronic hypnotic-drug use. Ineffectiveness, drug-withdrawal insomnia, and
      dependence.

PMID- 4358883
TI  - Massive hyperlipemia during estrogen therapy.

PMID- 4358884
TI  - Editorial: Insomnia.

PMID- 4358885
TI  - [Thyroid disorders (author's transl)].

PMID- 4358886
TI  - [Early manifestation of intracranial neoplasms (author's transl)].

PMID- 4358887
TI  - Avian leukosis-sarcoma virus antibodies in wildfowl, domestic chickens and man in
      Kenya.

PMID- 4358888
TI  - Activation of type C RNA tumor virus expressions in tumors induced by cell
      cultures transformed by polyoma virus.

PMID- 4358889
TI  - Neutralizing antibody against infectious canine hepatitis virus (ICHV) in
      veterinary workers' sera.

PMID- 4358891
TI  - Spontaneous in vitro transformation of leukocytes from a neonate.

PMID- 4358890
TI  - Effect of sex and sex hormones on plasma prothrombin and vitamin K deficiency.

PMID- 4358892
TI  - The growth of varicella-zoster virus in guinea pig embryo cells.

PMID- 4358893
TI  - Cytochalasin D enhances infectivity of poliovirus.

PMID- 4358894
TI  - Effects of corticosterone on phosphorylation of rat liver nuclear proteins in
      vitro.

PMID- 4358896
TI  - Kinetics of the phenotypic expression of mutations for streptomycin resistance
      induced by methylmethane sulfonate, N-methyl-N'-nitro-N-nitrosoguanidine, and
      ultraviolet light in Escherichia coli K-12.

PMID- 4358895
TI  - Remarks on mammographic calcifications.

PMID- 4358899
TI  - Renal trauma and preexisting lesions of kidney.

PMID- 4358897
TI  - Cytogenetic effect of alkylating mutagens as a function of the physiological
      state of seeds.

PMID- 4358900
TI  - [Simultaneous transfer of resistance to ampicillin and carbenicillin by R
      plasmids].

PMID- 4358901
TI  - [Adenomatoid tumor and carcinoma of the tube].

PMID- 4358902
TI  - Products of mitochondrial protein synthesis.

PMID- 4358898
TI  - [Cytogenetic changes associated with cellular infection with herpes simplex
      virus].

PMID- 4358903
TI  - [Mechanisms of action of oral contraceptives].

PMID- 4358905
TI  - In vitro effects of prolactin and cortisol on water permeability of the urinary
      bladder of the teleost Gillichthys mirabilis.

PMID- 4358904
TI  - Ultrastructural effects of dark-adaptation on eyes of a snail, Helix aspersa.

PMID- 4358907
TI  - What is your diagnosis? Mixed tumor.

PMID- 4358909
TI  - Statewide policies for planning nursing education in Minnesota.

PMID- 4358906
TI  - Cleavage initiating activities of sperm fractions injected into the egg of the
      medaka, Oryzias latipes.

PMID- 4358908
TI  - An investigation of hydrolytic techniques for the amino acid analysis of
      foodstuffs.

PMID- 4358910
TI  - Dopamine-induced inhibition of synaptic transmission in lumbar paravertebral
      ganglia of the dog.

PMID- 4358911
TI  - [The reactivity of various biochemical systems of birds under the influence of
      ionizing radiation].

PMID- 4358912
TI  - Effect of vasopressin administration on renal haemodynamic changes in rats
      treated with ACTH.

PMID- 4358914
TI  - Primary herpetic gingivostomatitis in the adult.

PMID- 4358913
TI  - The action of unconjugated bilirubin on some enzyme activities of in vitro
      cultured cells.

PMID- 4358915
TI  - Intraneuronal lipid droplets in irradiated nervous tissue.

PMID- 4358916
TI  - [Shifting in cell cycle of transplantation tumors. Cytophotometrical
      investigations (author's transl)].

PMID- 4358917
TI  - Ultrastructure of the protein containing vacuoles and hyaline droplets in rat
      adrenocortical cells following polybrene.

PMID- 4358918
TI  - [Cytomegalovirus infection].

PMID- 4358920
TI  - [Positive habituation and vestibular recruitment].

PMID- 4358921
TI  - Karyotypic variation in benign pleomorphic adenoma of the parotid and in normal
      salivary glands.

PMID- 4358919
TI  - Biochemical studies of otosclerosis. Phosphohydrolase activity in stapedial
      footplates.

PMID- 4358922
TI  - Action of metabolic hormones on the fine structure of liver cells. II. Effects of
      hypophysectomy and chronic administration of somatotropin.

PMID- 4358923
TI  - Acute renal failure in obstetrics.

PMID- 4358925
TI  - Malignant epithelial tumors of the parotid gland. Classification, staging and
      treatment.

PMID- 4358924
TI  - Immunologic response in gynecologic malignancy as demonstrated by the delayed
      hypersensitivity reaction: clinical correlations.

PMID- 4358926
TI  - Studies on the combined action of antibiotics on Pseudomonas aeruginosa strains.

PMID- 4358927
TI  - Studies on neutral esters of cyclic AMP.

PMID- 4358928
TI  - Independence of theta and TL surface antigens and killing by thymidine, cortisol,
      phytohemagglutinin, and cyclic AMP in a murine lymphoma.

PMID- 4358929
TI  - Nucleotide sequence analysis of DNA. XII. The chemical synthesis and sequence
      analysis of a dodecadeoxynucleotide which binds to the endolysin gene of
      bacteriophage lambda.

PMID- 4358931
TI  - Binding of trifluorolactate to pig heart H4-lactate dehydrogenase.

PMID- 4358930
TI  - Some properties of coupled hepatoma mitochondria exhibiting uncoupler-insensitive
      ATPase activity.

PMID- 4358932
TI  - Analysis of amino acid phenylthiohydantoins by high speed liquid chromatography.

PMID- 4358933
TI  - Alteration of NAD-linked malic enzyme-catalyzed reactions by sulfhydryl group
      modification.

PMID- 4358934
TI  - Carbamylphosphate synthetase of lactating bovine mammary tissue.

PMID- 4358936
TI  - Cyclic AMP phosphodiesterase activation by the histamine releasing agent,
      compound 48-80.

PMID- 4358935
TI  - Model reactions for the study of the interaction of sulfur dioxide with mammalian
      organisms.

PMID- 4358937
TI  - A specific spin labeling of the anticodon of E. coli tRNA-Glu.

PMID- 4358938
TI  - Polychlorinated biphenyls: hydroxylated urinary metabolites of 2,5,2',5'
      tetrachlorobiphenyl identified in rabbits.

PMID- 4358939
TI  - Conformational parameters for amino acids in helical, beta-sheet, and random coil
      regions calculated from proteins.

PMID- 4358940
TI  - Prediction of protein conformation.

PMID- 4358941
TI  - Changes in sulfhydryl groups of honeybee glyceraldehyde phosphate dehydrogenase
      associated with generation of the intermediate plateau in its saturation
      kinetics.

PMID- 4358943
TI  - Glucocorticoid receptors in mouse pituitary tumor cells. II. Nuclear binding.

PMID- 4358942
TI  - Estrogen receptor binding to isolated nuclei. A nonsaturable process.

PMID- 4358944
TI  - The dynamic structure of lipid membranes. A 13C nuclear magnetic resonance study
      using spin labels.

PMID- 4358946
TI  - Substrate-attached glycoproteins from normal and virus-transformed cells.

PMID- 4358945
TI  - Monomeric and dimeric forms of component II of the anthranilate synthetase-
      anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase complex of
      Salmonella typhimurium. Implications concerning the mode of assembly of the
      complex.

PMID- 4358948
TI  - A filter assay for thymidylate synthetase using 5-fluoro-2'-deoxyuridylate as an
      active site titrant.

PMID- 4358947
TI  - Structure and activity of methylated horse liver alcohol dehydrogenase.

PMID- 4358949
TI  - Physical identity of the SV40 deoxyribonucleic acid sequence recognized by the
      Eco RI restriction endonuclease and modification methylase.

PMID- 4358950
TI  - Derivatives of N-(N-(9-beta-D-ribofuranosylpurin-6-yl)carbamoyl)threonine in
      phosphodiesterase hydrolysates of wheat embryo transfer ribonucleic acid.

PMID- 4358951
TI  - Human placental tryptophanyl transfer ribonucleic acid synthetase. Purification
      and subunit structure.

PMID- 4358952
TI  - Human tryptophanyl transfer ribonucleic acid synthetase. Comparison of the
      kinetic mechanism to that of the Escherichia coli tryptophanyl transfer
      ribonucleic acid synthetase.

PMID- 4358953
TI  - Malignant fibrous histiocytoma with widespread metastases. Autopsy study.

PMID- 4358954
TI  - Mucinous adenocarcinoma of the renal pelvis. Report of two cases.

PMID- 4358955
TI  - Elastosis in breast cancer.

PMID- 4358956
TI  - Familial arrhenoblastoma and thyroid adenoma.

PMID- 4358957
TI  - Malignant chemodectoma presenting as a miliary pulmonary infiltrate.

PMID- 4358958
TI  - [Analgometric determination of the anesthetic action of alkosin].

PMID- 4358959
TI  - Studies on the quaternary structure of the first enzyme for histidine
      biosynthesis.

PMID- 4358960
TI  - On the mechanism of the inhibitory action of 2-amino-4,6-dichloropyrimidine on
      poliovirus growth.

PMID- 4358961
TI  - Irreversible impairment produced by guanidine on the functions of poliovirus
      proteins.

PMID- 4358962
TI  - Morphological and enzymehistochemical changes in the interscapular adipose tissue
      of adult guinea-pigs during prolonged exposure to cold.

PMID- 4358963
TI  - Localization of genes on human chromosomes by studies of human-Chinese hamster
      somatic cell hybrids. Assignment of PGM3 to chromosome C6 and regional mapping of
      the PGD, PGM1 and pep-C genes on chromosome A1.

PMID- 4358965
TI  - Syrian hamster-human somatic cell hybrids: isolation and characterization.

PMID- 4358964
TI  - Chromosome assignments of genes in man using mouse-human somatic cell hybrids:
      mitochondrial superoxide dismutase (indophenol oxidase-B, tetrameric) to
      chromosome 6.

PMID- 4358967
TI  - [Comparative cytologic study on the influence of plutonium and silica inhalation
      on the behavior of alveolar macrophages].

PMID- 4358966
TI  - [Influence of the nature of dust and pulmonary load on clearance].

PMID- 4358968
TI  - Long-term storage, migration and elimination of dust in the lungs of animals,
      with special respect to the influence of polyvinyl-pyridine-N-oxide.

PMID- 4358969
TI  - Influence of BCG on lymphatic lung clearance in rats.

PMID- 4358970
TI  - The relationship between duration of dust inhalation of a coal-quartz mixture and
      dust retention, lung function and pathology on rats.

PMID- 4358971
TI  - Lung function studies in experimental silicosis with a radiospirometric technique
      and some observations on a technique for inducing unilateral silicosis. A
      preliminary report.

PMID- 4358972
TI  - Observations on the mechanism of silicotic fibrogenesis.

PMID- 4358973
TI  - Investigations on the aetiology of coal workers' pneumoconiosis with the use of
      PVN-oxide.

PMID- 4358974
TI  - [Action of aluminum compounds in the formation and evolution of experimental
      silicotic lesions].

PMID- 4358975
TI  - On the cell toxicity of mineral dusts.

PMID- 4358976
TI  - [Electron microscope study of quartz dust phagocytosis].

PMID- 4358977
TI  - The cytotoxic action and the semiconductor properties of mine dusts.

PMID- 4358979
TI  - Post-hospital discharge: patient care and utilization of services and facilities.

PMID- 4358978
TI  - The role of some physical and chemical properties of mine dust in the development
      of pneumoconiosis.

PMID- 4358980
TI  - "The central areas" of denervated canine muscle.

PMID- 4358981
TI  - Pathology of Clostridium welchii type D enterotoxaemia. I. Biochemical and
      haematological alterations in lambs.

PMID- 4358982
TI  - Pathology of Clostridium welchii type D enterotoxaemia. II. Structural and
      ultrastructural alterations in the tissues of lambs and mice.

PMID- 4358983
TI  - Pathology of Clostridium welchii type D enterotoxaemia. 3. Basis of the
      hyperglycaemic response.

PMID- 4358984
TI  - Spontaneous malignant neoplasms in dasyurid marsupials.

PMID- 4358985
TI  - Pulmonary adenomatosis in ageing mice.

PMID- 4358986
TI  - Terminal oxidases and carbon monoxide-reacting haemoproteins in the
      trypanosomatid, Crithidia fasciculata.

PMID- 4358987
TI  - Chemistry of the filaments and tubules of brain.

PMID- 4358988
TI  - Electronystagmographic comparison of acute idiopathic and herpes zoster facial
      paralysis.

PMID- 4358989
TI  - Letter: Gas gangrene.

PMID- 4358990
TI  - [When is pancreatectomy indicated?].

PMID- 4358991
TI  - [Therapy of vitamin D-resistant rickets by means of dihydrotachysterol (author's
      transl)].

PMID- 4358992
TI  - Fatal infectious mononucleosis in a family.

PMID- 4358993
TI  - Letter: Potassium, aldosterone and renin inter-relations.

PMID- 4358994
TI  - Depolarization generated by acetylcholine through activation of
      triphosphoinositide phosphomonoesterase.

PMID- 4358995
TI  - [The threshold and temporal characteristics of cat lateral geniculate body
      responses to electrical stimulation of the optic tract].

PMID- 4358996
TI  - [The chemical sensitivity and reactions to synaptic stimulation of Lymnaea
      stagnalis neurons].

PMID- 4358997
TI  - [Reticulofugal influences on interneurons distributed in the lateral portions of
      cat spinal cord gray matter].

PMID- 4358998
TI  - Physostigmine in choreiform movement disorders.

PMID- 4358999
TI  - Evaluation of antithymocyte globulin in acute relapses of multiple sclerosis.

PMID- 4359000
TI  - An experimental myopathy secondary to excessive acetylcholine release.

PMID- 4359001
TI  - Automatic midline echoencephalography. Examination of 3,333 consecutive cases
      with the automatic midline computer.

PMID- 4359002
TI  - A natriuresis receptor at the carotid bifurcation specifically activated by
      oxytocin.

PMID- 4359003
TI  - A new model for transmitter mobilization in the frog neuromuscular junction.

PMID- 4359005
TI  - Angiographic findings in benign liver cell tumors.

PMID- 4359004
TI  - [Enzymatic oxidation of retinal into retinoic acid and assimilation of vitamin A
      and beta-carotene].

PMID- 4359006
TI  - A complication of skin testing with iodinated radiographic contrast medium.

PMID- 4359007
TI  - Total body radionuclide localization in infants.

PMID- 4359008
TI  - A new method for radionuclide imaging of myocardial infarcts.

PMID- 4359010
TI  - [After care services].

PMID- 4359009
TI  - Pediatric urology.

PMID- 4359011
TI  - [The so-called cystosarcoma phylloides of the breast].

PMID- 4359012
TI  - [Physiologically active molecules and their evolution].

PMID- 4359013
TI  - [Mechanisms of convergence in the phylogenesis of integrative systems of the
      brain].

PMID- 4359015
TI  - [A psychophysiologic study of nocturnal sleep].

PMID- 4359014
TI  - [Plastic reorganization of the reactivity of cortical neurons].

PMID- 4359016
TI  - Pharmacokinetics and dosing of antimicrobial agents in renal impairment. I.

PMID- 4359017
TI  - Collagen cross-linking. Isolation of cross-linked peptides from collagen of
      chicken bone.
AB  - Cross-linked peptides were isolated from chicken bone collagen that had been
      digested with CNBr or with bacterial collagenase. Analyses of (3)H radioactivity
      in disc electrophoretic profiles of the CNBr peptides from bone collagens that
      had been treated with NaB(3)H indicated that a major site of intermolecular cross
      linking in chicken bone collagen is located between the carboxy-terminal region
      of an alpha1 chain and a small CNBr peptide, probably situated near the amino
      terminus of an alpha1 or alpha2 chain in an adjacent collagen molecule. A small
      amount of this cross-linked CNBr peptide was isolated from a CNBr digest of
      chicken bone collagen by column chromatography. Amino acid analysis showed that
      the CNBr peptide, alpha1CB6B, the carboxy-terminal peptide of the alpha1 chain,
      was the major CNBr peptide in the preparation, and the reduced cross-linking
      components were identified as hydroxylysinohydroxynorleucine (HylOHNle), with a
      smaller amount of hydroxylysinonorleucine (HylNle). However, the composition and
      the low recovery of the cross-linking amino acids suggested that the preparation
      was a mixture of CNBr peptides alpha1CB6B and alpha1CB6B cross-linked to a small
      CNBr peptide whose identity could not be determined. A small cross-linked peptide
      was isolated from chicken bone collagen that had been reduced with NaB(3)H(4) and
      digested with bacterial collagenase. This peptide was the major cross-linked
      peptide in the digest and contained a stoicheiometric amount of the reduced cross
      linking compounds. A peptide which had the same amino acid composition, but
      contained the cross-linking compounds in their reducible forms, was isolated from
      a collagenase digest of chicken bone collagen that had not been treated with
      NaBH(4). The absence of the reduced cross-links from this peptide indicates that,
      at least for the cross-linking site from which the peptide derives, natural
      reduction is not a significant pathway for biosynthesis of stable cross-links.
      However, most of the reducible cross-linking component in the peptide appeared to
      stabilize in the bone collagen by rearrangement from aldimine to ketoamine form.

PMID- 4359018
TI  - N-acetyl-beta-D-hexosaminidase component A. Different forms in human tissues and
      fluids.
AB  - 1. Hexosaminidase A of human serum was resolved into two components, a minor form
      with properties identical with those of the single hexosaminidase A component of
      human liver, and a major form with significantly different properties. 2. The
      major serum hexosaminidase A form was eluted from a DEAE-cellulose column at a
      lower salt concentration than that required to elute the liver form. 3. A
      multiple-pass technique was used to elute the major serum enzyme A from a
      Sephadex G-150 column before that of liver enzyme A. 4. Clostridium perfringens
      neuraminidase converted the major component of serum hexosaminidase A into a form
      that was held less tightly by DEAE-cellulose, but the minor component of the A
      enzyme of serum, and the A enzyme of liver were not affected. 5. The
      hexosaminidase A from tears was similar to the A enzyme from serum, whereas those
      from several human tissues and from urine and lymph were similar to the liver
      form. 6. The A enzyme from serum may be derived from the A enzyme from liver by
      glycosylation before secretion.

PMID- 4359020
TI  - The use of sodium perchlorate in deproteinization during the preparation of
      nucleic acids.
AB  - Sodium perchlorate in high concentrations will remove from solution the detergent
      sodium dodecyl sulphate and protein complexed with it. This and the failure of
      proteins to be precipitated by ethanol from solutions containing a high
      concentration of sodium perchlorate can be utilized as efficient, rapid and
      simple deproteinization procedures during the preparation of nucleic acids.

PMID- 4359021
TI  - Phosphorylation of myelin basic protein by an adenosine 3':5'-cyclic
      monophosphate-dependent protein kinase.
AB  - Myelin basic protein was shown to be a substrate for protein kinase from rabbit
      muscle. One of the major sites of phosphorylation was the serine residue in the
      sequence Gly-Arg-Gly-Leu-Ser-Leu. The arginine residue in this sequence is known
      to be a substrate for a protein methylase.

PMID- 4359019
TI  - Functional groups in the activity and regulation of Escherichia coli citrate
      synthase.
AB  - 1. Citrate synthase has been purified from Escherichia coli and shown to exist at
      an equilibrium between three forms: monomer (mol.wt. 57000), tetramer (mol.wt.
      230000) and, possibly, octamer. Modification of the enzyme by photo-oxidation and
      by treatment with specific chemical reagents has been carried out to gain
      information on the amino acid residues involved in enzymic activity and in the
      inhibition of activity by NADH and alpha-oxoglutarate. 2. Several photo
      oxidizable amino acids appear to be involved in activity. The nature of the pH
      dependence of their rates of photo-oxidation with Methylene Blue suggests that
      these are histidines, a conclusion supported by the greater rate of photo
      inactivation with Rose Bengal and the destruction of activity by diethyl
      pyrocarbonate. 3. The participation of histidine at the alpha-oxoglutarate
      effector site is indicated by photo-oxidation and the participation of cysteine
      at the NADH effector site suggested by photo-oxidation is confirmed by the
      desensitization to NADH produced by treatment with 5,5'-dithiobis-(2
      nitrobenzoate). Inactivation of the enzyme after modification with this reagent
      suggests the additional involvement of cysteine in catalytic activity. 4. Amino
      acid analyses of native and photo-oxidized enzyme are consistent with these
      conclusions. 5. Modification with 2-hydroxy-5-nitrobenzyl bromide indicates the
      participation of tryptophan in the activity of the enzyme.

PMID- 4359022
TI  - Structural investigations of lipid, polypeptide and protein multilayers.

PMID- 4359023
TI  - [Study by fluorescence of the TNS complex with placental 17 beta-hydroxysteroid
      dehydrogenase].

PMID- 4359024
TI  - The high molecular weight RNA of Visna virus.

PMID- 4359025
TI  - [Preparation of plasma membranes of Seva ascitic cells].

PMID- 4359026
TI  - Strychnine interactions with acetylcholine, dopamine and serotonin receptors in
      Aplysia neurons.

PMID- 4359027
TI  - [Delimitation of the ascending pathways of the ponto-geniculo-occipital activity
      in the cat (author's transl)].

PMID- 4359028
TI  - Attention of transmission through glomeruli of olfactory bulb on paired shock
      stimulation.

PMID- 4359029
TI  - Relation of glomerular neuronal activity to glomerular transmission attenuation.

PMID- 4359030
TI  - The synthesis of p-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl) P2-ficaprenyl
      pyrophosphate.

PMID- 4359031
TI  - Angiography of renal capsular complex in normal and pathological conditions and
      its diagnostic implications.

PMID- 4359032
TI  - Vasodilator reserve, parallel vascular beds, and significant stenosis: a review
      for the angiographer.

PMID- 4359033
TI  - The therapeutic effects of cyclacillin in acute sinusitis: in vitro and in vivo
      correlations in a placebo-controlled study.

PMID- 4359034
TI  - The acute effect of tetracosactrin on carbohydrate, insulin, glucagon, gastrin
      and lipid metabolism in rheumatoid arthritis.

PMID- 4359035
TI  - The induction of fibrogenesis by silica-treated alveolar macrophages.

PMID- 4359036
TI  - Inhibition of phosphorylase-a by fructose-1-phosphate, alpha-glycerophosphate and
      fructose-1,6-diphosphate: explanation for fructose-induced hypoglycaemia in
      hereditary fructose intolerance and fructose-1,6-diphosphatase deficiency.

PMID- 4359038
TI  - Prostaglandins as modulators of the autonomic nervous system.

PMID- 4359037
TI  - Prostaglandins and renal function.

PMID- 4359039
TI  - Prostaglandins and the thyroid gland.

PMID- 4359040
TI  - Ultrastructural observations on human oocytes fertilized in vitro.

PMID- 4359041
TI  - [Supra-renal scintigraphy using 131-I-19-iodocholesterol with special reference
      to renal insufficiency (author's transl)].

PMID- 4359042
TI  - [Arteriographic and clinical features of the steal phenomenon involving the
      branches of the aortic arch (author's transl)].

PMID- 4359043
TI  - [The value of arteriography in acute ischaemia of the extremities, and after
      surgical treatment (author's transl)].

PMID- 4359044
TI  - [Intra-hepatic obstruction in portal hypertension. Its radiological
      differentiation and clinical significance (author's transl)].

PMID- 4359045
TI  - [Venous collateral circulation following occlusion of the inferior vena cava by
      tumours shown by oil emboli in the liver after lymphography (author's transl)].

PMID- 4359046
TI  - [Hampton's line in ulcerating early carcinoma of the stomach (author's transl)].

PMID- 4359047
TI  - [Retro-caval ureter (author's transl)].

PMID- 4359048
TI  - [Changes in leucineaminopeptidase activity in the urine caused by contrast media
      (author's transl)].

PMID- 4359049
TI  - [Ossification in the patellar ligament and Osgood-Schlatter's disease (author's
      transl)].

PMID- 4359050
TI  - [Bland sclerosing spondylitis (author's transl)].

PMID- 4359051
TI  - [Demonstration of chronic insertion tendinitis on the humeral epicondyle by means
      of soft tissue radiography (author's transl)].

PMID- 4359052
TI  - [Endotracheal position of a plasmacytoma].

PMID- 4359053
TI  - [Renal artery calcification in a diabetic with Monckeberg sclerosis].

PMID- 4359054
TI  - [Dissecting aortic aneurysm--false diagnosis following cardial venous aortography
      in luetic mesaortitis].

PMID- 4359055
TI  - [A triple preformed ureter].

PMID- 4359056
TI  - [Diagnosis of catheter fragments].

PMID- 4359057
TI  - [Progressive scleroderma of the fingers shown by a soft tissue technique].

PMID- 4359058
TI  - [Observation on the time course of progressive myositis ossificans].

PMID- 4359059
TI  - [Ischemic bowel diseases (author's transl)].

PMID- 4359060
TI  - A rapid screening procedure for some "street-drugs" by thin-layer chromatography.
      II. Cocaine, heroin, local anesthetics and mixtures.

PMID- 4359061
TI  - Separation of diphosphoinositide and triphosphoinositide on oxalate-impregnated
      silica gel columns.

PMID- 4359062
TI  - Intraoperaoperative echoencephalography.

PMID- 4359063
TI  - Control of retinal sensitivity. I. Light and dark adaptation of vertebrate rods
      and cones.
AB  - Rods and cones in Necturus respond with graded hyperpolarization to test flashes
      spanning about 3.5 log units of intensity. Steady background levels hyperpolarize
      the rods, and the rod responses become progressively smaller as background level
      is increased. In cones, higher background levels reduce the effectiveness of test
      flashes, so higher ranges of test intensities are required to elicit the full
      range of graded responses. When backgrounds are terminated, cones return rapidly,
      but rods return slowly to the dark potential level. The effects of backgrounds on
      both rods and cones can be observed at intensities that cause negligible
      bleaching as determined by retinal densitometry. During dark adaptation, changes
      are observed in the rods and cones that are similar to those produced by
      backgrounds. Receptor sensitivities, derived from these results, show that rods
      saturate, cones obey Weber's law, and sensitization during dark adaptation
      follows a two-phase time-course.

PMID- 4359064
TI  - Control of retinal sensitivity. II. Lateral interactions at the outer plexi form
      layer.
AB  - Test stimuli, presented at the center of the bipolar cell receptive field,
      spanning less than 2 log units of intensity, elicit the full range of graded
      response. The intensity range of test stimuli that elicits the graded response
      depends upon the background conditions. A higher range of log test intensities is
      required to elicit the graded bipolar response in the presence of surround
      backgrounds. But surround backgrounds can also serve to unsaturate the bipolar
      response and thereby increase sensitivity under certain conditions. The results
      suggest that a second stage of sensitivity-control is mediated by the horizontal
      cell system at the outer plexiform layer, concatenated with the effects of
      adaptation in the photoreceptors.

PMID- 4359065
TI  - Control of retinal sensitivity. 3. Lateral interactions at the inner plexiform
      layer.
AB  - Both the "on" and the "on-off" ganglion cells in the mudpuppy retina generate
      graded responses over a narrow range of log test intensities. Sustained full
      field or surround backgrounds change the range of center log test intensities
      that elicits the graded response for both cell types. The on-off, but not the on
      ganglion cells are further affected by moving or flashing surround backgrounds.
      These cells are hyperpolarized, threshold is elevated, and the entire graded
      range of response is elicited by a higher range of log center test intensities.
      Depolarizing activity is elicited in amacrine cells by moving backgrounds that
      affect the on-off ganglion cells, but bipolar activity is unaffected. These
      results suggest that the amacrine cells at the inner plexiform layer mediate a
      third stage of sensitivity control in the retina, increasing threshold for
      response to change specifically in the on-off ganglion cells.

PMID- 4359066
TI  - Sequence data: magnitude and implications of some ambiguities.

PMID- 4359067
TI  - A systematist looks at cytochrome c.

PMID- 4359068
TI  - Serotonergic and antiserotonergic influences on amphetamine-induced stereotyped
      behavior.

PMID- 4359069
TI  - Acetylcholine and cortical excitation by pyramidal tract collaterals.

PMID- 4359070
TI  - Observations on bluetongue and epizootic hemorrhagic disease viruses in white
      tailed deer: (1) distribution of virus in the blood (2) cross-challenge.

PMID- 4359071
TI  - [Liver embolism caused by lymphangiography of the legs].

PMID- 4359073
TI  - [Coexistent pregnancy and isolated ACTH deficiency: case report (author's
      transl)].

PMID- 4359072
TI  - [Investigation of lecithin-cholesterol-acyltransferase (LACT) activity in the
      serum of three patients with Tangier disease (author's transl)].

PMID- 4359074
TI  - The adsorption of water in a chlorophyll extract.

PMID- 4359075
TI  - The molecular organization of the active sites of the microsomal cytochrome P
      450.

PMID- 4359076
TI  - Origin of the mitochondrial RNA of animal tissues. 2. Hybridization with nuclear
      DNA.

PMID- 4359077
TI  - Mesodermal mixed tumors of the uterine corpus.

PMID- 4359078
TI  - The effect of large doses of medroxyprogesterone acetate (MPA) on urinary
      estrogen levels and serum levels of cortisol T4 LH and testosterone in patients
      with advanced cancer.

PMID- 4359079
TI  - Pituitary-adrenal hormones and extinction of rewarded behaviour in the rat.

PMID- 4359080
TI  - Neurologic complications of corticosteroid therapy.

PMID- 4359081
TI  - Increased serum conjugated bilirubin in hemolytic anemia.

PMID- 4359082
TI  - Female steroid hormones and target cell nuclei.
AB  - The data discussed herein demonstrate the great variation in target-tissue
      response that can occur after administration of steroid hormones. The female sex
      steroids can exert regulatory effects on the synthesis, activity, and possibly
      even the degradation of tissue enzymes and structural proteins. Each response,
      nevertheless, appears to be dependent on the synthesis of nuclear RNA. In many
      instances, the steroid actually promotes a qualitative change in the base
      composition and sequence of the RNA synthesized by the target cell, implying a
      specific effect on gene transcription. Most important is our direct quantitative
      evidence that sex steroids cause a net increase in the intracellular amounts of
      specific mRNA molecules in target tissues. It thus appears that we are
      discovering a pattern of steroid hormone action which includes (Fig. 1): (i)
      uptake of the hormone by the target cell and binding to a specific cytoplasmic
      receptor protein; (ii) transport of the steroid-receptor complex to the nucleus;
      (iii) binding of this "active" complex to specific "acceptor" sites on the genome
      (chromatin DNA and acidic protein); (iv) activation of the transcriptional
      apparatus resulting in the appearance of new RNA species which includes specific
      mRNA's; (v) transport of the hormone-induced RNA to the cytoplasm resulting in
      synthesis of new proteins on cytoplasmic ribosomes; and (vi) the occurrence of
      the specific steroid-mediated "functional response" characteristic of that
      particular target tissue. To elucidate fully the mechanism of steroid hormone
      action we must study the biochemistry of the process by which information held by
      the steroid hormone-receptor complex is transferred to the nuclear transcription
      apparatus. If our assumptions are correct, we should ultimately be able to
      discover how this hormone-receptor complex exerts a specific regulatory effect on
      nuclear RNA metabolism. Such regulation might be achieved (i) by direct effects
      on chromatin template leading to increased gene transcription and thus RNA
      synthesis; (ii) by activation of the polymerase complex itself; (iii) by
      inhibition of RNA breakdown; or (iv) by intranuclear processing of large
      precursor molecules so that smaller biologically active sequences are produced,
      and (v) by transport of RNA from the nucleus to the cytoplasmic sites of cellular
      protein synthesis.

PMID- 4359083
TI  - Failure to confirm cyclic AMP as second messenger for norepinephrine in rat
      cerebellum.
AB  - Microiontophoretic applications of adenosine 3',5'-monophosphate (cyclic AMP) to
      spontaneously active, electrophysiologically identified Purkinje cells of the rat
      cerebellum failed to mimic the strong depressant action of norepinephrine on the
      same cells. These findings, in combination with a reevaluation of other studies,
      cast doubt on the hypothesis that cyclic AMP mediates the depressant actions of
      norepinephrine in the cerebellum.

PMID- 4359084
TI  - Viscosity of cellular protoplasm.
AB  - The protoplasmic viscosity was studied by using a small spin label having high
      permeability and broad solubility properties and nickel chloride as an
      extracellular spin-subtracting agent to localize signal inside cells. The
      viscosity is variable and in some cells is many times that of water or
      phospholipids, suggesting that lateral diffusion in biological membranes is
      important to cell function.

PMID- 4359085
TI  - Diphenylhydantoin: effects on calcium metabolism in the chick.
AB  - Rickets, hypocalcemia, decreased duodenal calcium transport, and reduction of
      calcium binding protein have been produced in chicks treated with
      diphenylhydantoin. These effects are directly related to diphenylhydantoin dose
      and inversely related to the intake of vitamin D(3) (cholecalciferol).

PMID- 4359086
TI  - Conclusions from Bell's phenomenon variants.

PMID- 4359087
TI  - [Labile hypertension: hormonal characteristic and implications of the "second
      messenger"].

PMID- 4359088
TI  - Observations on the role of viruses in pneumonia of calves.

PMID- 4359090
TI  - [Role of potassium ions in regulation of fructosediphosphatase activity of
      oocytes and embryos of the loach Misgurnus fossilis].

PMID- 4359089
TI  - [Structural-functional characteristics of the synaptic apparatus in insects].

PMID- 4359091
TI  - [Extrinsic stenosis of the mean hepatic artery through hyperplasia of nervous
      fibers (author's transl)].

PMID- 4359092
TI  - The IBR-IPV virus-serum neutralization test. Sensitivity and significance of the
      tissue culture tube test.

PMID- 4359093
TI  - Proteases of Clostridium botulinum. V. Studies on the serological relationship
      between proteases from Clostridium botulinum and other spore-forming bacteria.

PMID- 4359094
TI  - Peripheral plasma levels of corticosteroids in normal beagles and greyhounds
      measured by a rapid competitive protein binding technique.

PMID- 4359095
TI  - Primary congenital eversion of the eyelids.

PMID- 4359096
TI  - Stein-Leventhal syndrome in a 12-year-old girl.

PMID- 4359097
TI  - Epstein-Barr virus antibodies in the cerebrospinal fluid. A case of infectious
      mononucleosis with encephalitis.

PMID- 4359098
TI  - Galactography: a method of detection of unsuspected cancers.

PMID- 4359099
TI  - Comparison of counterimmunoelectrophoresis with other serologic tests in the
      diagnosis of amebiasis.

PMID- 4359100
TI  - Synaptosomes, a possible system for the study of synaptic transmission.

PMID- 4359101
TI  - Prolongation of a pancuronium-induced neuronmuscular blockade by polymyxin B.

PMID- 4359102
TI  - Isolated facial numbness. Clinical significance and relation to trigeminal
      neuropathy.

PMID- 4359103
TI  - Endoscopic cholangiography for biliary system diagnosis.

PMID- 4359104
TI  - Studies on bone matrix glycoproteins. Incorporation of (1-14C)glucosamine and
      plasma (14C)glycoprotein into rabbit cortical bone.
AB  - The radioactively labelled constituents present in bone matrix were compared 12
      days after injection of either [(14)C]glucosamine or plasma [(14)C]glycoprotein.
      Both precursors are utilized in the synthesis of organic matrix by bone tissue.
      Cortical bone from animals injected with [(14)C]glucosamine contains
      radioactivity derived from glucosamine and plasma glycoproteins and all
      glycoprotein fractions are labelled. Plasma [(14)C]glycoprotein labels the less
      acidic glycoproteins to a greater extent than the more acidic components. An
      antibody has been raised against the less-acidic-glycoprotein fraction of bone.
      The latter contains a glycoprotein of alpha-mobility that appears to be
      concentrated specifically in bone tissue and which is present also in plasma.
      This alpha-glycoprotein accounts for a large proportion of the components
      labelled and retained in bone matrix after [(14)C]glucosamine injection.

PMID- 4359105
TI  - Transport of methionine and proline by rat liver slices and the effect of certain
      hormones.
AB  - 1. Transport characteristics of l-methionine and l-proline in rat liver slices in
      vitro were studied. 2. Intracellular concentration gradients for methionine were
      obtained. 3. Methionine uptake was inhibited by iodoacetate, dinitrophenol, Na(+)
      free media and also by glycine, lysine, cysteine and dithiothreitol but not by
      alpha-aminoisobutyrate. 4. The rate of methionine metabolism in the slice was
      slow. 5. Puromycin inhibited methionine incorporation into protein, but not
      methionine uptake. 6. Methionine inhibited the transport of alpha
      aminoisobutyrate but not of cystine. 7. Efflux and exchange diffusion of
      methionine was studied. 8. Amino acid transport in rat liver slices was not
      affected by thyroidectomy. 9. Addition of insulin, glucagon, adrenaline or
      cortisol did not affect the transport of methionine. 10. Addition of 6-N,2'-O
      dibutyryladenosine 3':5'-cyclic monophosphate increased methionine transport
      after a 120min incubation period in some experiments. 11. Studies of l-proline
      transport were invalidated because of the rapid evolution of CO(2) from the
      substrate.

PMID- 4359106
TI  - Steroid-binding properties and stabilization of cytoplasmic glucocorticoid
      receptors from rat thymus cells.
AB  - 1. A competitive binding assay was adapted for determination of the specific
      binding of glucocorticoids to cytoplasmic receptors from rat thymus cells. The
      steroid-receptor complexes prepared by incubation of a cytoplasmic fraction from
      rat thymus cells with [1,2-(3)H(2)]cortisol or with [1,2,4-(3)H(3)]triamcinolone
      acetonide had rates of dissociation at 37 degrees C similar to those from intact
      cells. 2. The cytoplasmic receptor was unstable at 3 degrees C, but the rate of
      inactivation was decreased in the presence of 2.5mm-EDTA. The steroid-receptor
      complex was stable. 3. Rate constants for association and for dissociation, and
      association constants, were determined for the interactions of cortisol,
      cortexolone, dexamethasone and triamcinolone acetonide with the cytoplasmic
      receptor at 3 degrees C. Differences in the association constants for different
      steroids could largely be accounted for by the differences in the rate constants
      for dissociation, but the rate constants for association did not vary greatly;
      the implications of these findings for the nature of the steroid-binding site are
      discussed. 4. A cytoplasmic fraction prepared from cells which had been incubated
      at 37 degrees C under anaerobic conditions bound much less [1,2-(3)H(2)]cortisol
      than did a fraction from aerobic cells, but the binding capacity was restored
      after exposure of the anaerobic cells to O(2). 5. The specific binding of [1,2
      (3)H(2)]-cortisol to intact thymus cells incubated aerobically was not affected
      by the presence of 0.1mm-cycloheximide, nor did this concentration of
      cycloheximide inhibit the recovery of specific binding observed when anaerobic
      cells were transferred to an aerobic atmosphere. 6. The energy dependence of
      specific binding of cortisol to the receptor is discussed with reference to
      possible mechanisms.

PMID- 4359108
TI  - [Demonstration of an antiviral substance in the culture medium of cells of the
      NZB mouse].

PMID- 4359107
TI  - [Role of collagen during the morphogenesis of the feathers and claws in chicks].

PMID- 4359109
TI  - Rections of aliphatic methanesulfonates.

PMID- 4359110
TI  - The phospholipid composition of human serum lipoprotein fractions separated by
      electrophoresis on agarose gel. Demonstration of a fraction with high
      lysolecithin content.

PMID- 4359111
TI  - Purification and some properties of the enzyme which conjugates
      sulfobromophthalein to glutathione in rat liver.

PMID- 4359112
TI  - Urinary excretion of neutral steroid glucuronides with reference to the menstrual
      cycle.

PMID- 4359113
TI  - The interaction between estradiol and human platelets.

PMID- 4359114
TI  - Type 3 hyperlipoproteinaemia.

PMID- 4359115
TI  - Type V hyperlipoproteinaemia.

PMID- 4359116
TI  - Lipoproteins and hyperlipoproteinaemia.

PMID- 4359118
TI  - Type I hyperlipoproteinaemia.

PMID- 4359117
TI  - Type IV hyperlipoproteinaemia.

PMID- 4359119
TI  - Characteristics of cyclic 3',5'-nucleotide phosphodiesterase from the brain of
      the Madagascar cockroach (Gromphadorhina portentosa).

PMID- 4359120
TI  - A biochemical basis for differences in maximal diving time in aquatic mammals.

PMID- 4359121
TI  - Estradiol receptors in female rat hypothalamus in the developmental stages and
      during pubescence.

PMID- 4359122
TI  - Heterogeneity of thyroid iodine turnover: last come, last served phenomenon.

PMID- 4359123
TI  - Effects of prostaglandin E1, ethanol and TSH on the adenylate cyclase activity of
      beef thyroid plasma membranes and cyclic AMP content of dog thyroid slices.

PMID- 4359124
TI  - Specificity of nucleotide-induced insulin secretion.

PMID- 4359125
TI  - Estradiol and 20alpha-dihydroprogesterone dehydrogenase activities in human
      endometrium during the menstrual cycle.

PMID- 4359126
TI  - The effects of dibutyryl cyclic AMP, aminophylline and propranolol on PTE-induced
      bone resorption in vitro.

PMID- 4359127
TI  - Physical characteristics of the Ca++ compartments associated with in vitro ACTH
      release.

PMID- 4359128
TI  - Effect of dibutyryl cyclic AMP on in vitro rat testis DNA, RNA and protein
      labeling.

PMID- 4359129
TI  - Variations in the levels of cytoplasmic glucocorticoid receptors in lungs of
      various species at different developmental stages.

PMID- 4359130
TI  - Development of a radioligand tissue receptor assay for human follicle-stimulating
      hormone.

PMID- 4359131
TI  - Environmental calcium and the sensitivity of killifish (Fundulus heteroclitus) in
      bioassays for the hypocalcemic response to Stannius corpuscles from killifish and
      cod (Gadus morhua).

PMID- 4359132
TI  - The binding of tritiated aldosterone in the rat liver cytosol.

PMID- 4359133
TI  - Changes in plasma ACTH and corticosteroid of the maternal and fetal sheep during
      hypoxia.

PMID- 4359134
TI  - Adenylate cyclase activity in bovine adrenal medulla.

PMID- 4359135
TI  - An ultrastructural stereologic study of the effects of 3',5'-cyclic nucleotides
      on the zona glomerulosa of rat adrenal cortex.

PMID- 4359136
TI  - Structural studies on the heptose region of Salmonella lipopolysaccharides.

PMID- 4359138
TI  - Ribonuclease activity in Escherichia coli polyribosomes.

PMID- 4359137
TI  - Comparative study of photophosphorylation coupling factor-ligand complex by
      circular dichroism and chemical isolation.

PMID- 4359139
TI  - Intracellular titration of cyclic AMP bound to receptor proteins and correlation
      with cyclic-AMP levels in the surviving rat diaphragm.

PMID- 4359140
TI  - A new immobilized NAD+ analogue, its application in affinity chromatography and
      as a functioning coenzyme.

PMID- 4359141
TI  - 5-Aminolevulinic-acid synthetase of Rhodopseudomonas spheroides Y. Kinetic
      mechanism and inhibition by ATP.

PMID- 4359142
TI  - Fluorescence study of liver-alcohol-dehydrogenase complexes with berberine and
      other ligands.

PMID- 4359143
TI  - Rate-limiting factors in ethanol oxidation by isolated rat-liver parenchymal
      cells. Effect of ethanol concentration, fructose, pyruvate and pyrazole.

PMID- 4359144
TI  - [Transfer of mannose from GDP mannose to lipid acceptors in Aspergillus niger].

PMID- 4359145
TI  - The effects of trypsin on the membrane-bound nicotinic acid oxidase in
      Pseudomonas ovalis Chester.

PMID- 4359146
TI  - Purification of plasma membranes from immature brain.

PMID- 4359148
TI  - Updating the sleeping pill.

PMID- 4359147
TI  - A correlation between the buoyant density and the sedimentation coefficient of
      EMC viral polyribosomes.

PMID- 4359149
TI  - Problems of gravimetric dust sampling.

PMID- 4359150
TI  - [Calculation of conversion factors for different fine dust ranges].

PMID- 4359151
TI  - Immunological factors in coalworkers' pneumoconiosis.

PMID- 4359152
TI  - Mixed dust fibrosis in mineworkers.

PMID- 4359153
TI  - Mineralogical characteristics of airborne dust in coal mines of Western Germany
      and their relations to pulmonary changes of coal hewers.

PMID- 4359154
TI  - Respirable dust in bituminous coal mines in the U.S.

PMID- 4359155
TI  - Characteristics of the airborne dust in British coal mines.

PMID- 4359156
TI  - The determination of the size distribution of mine dusts using the Coulter
      Counter.

PMID- 4359157
TI  - [The role of occupational exposure to dust in the etiology of chronic bronchitis
      in coal miners].

PMID- 4359158
TI  - The relation between pneumoconiosis and dust-exposure in British coal mines.

PMID- 4359159
TI  - The attack rate of progressive massive fibrosis in British coalminers.

PMID- 4359160
TI  - A simple dust index applicable to various dust-contaminated occupations--a
      program of action for silicosis prophylaxis.

PMID- 4359161
TI  - Histochemistry of enzyme response to trauma in the neocortex and corpus callosum
      of developing rat brain.
AB  - The enzyme response to injury of the brain was well localized and limited. Some
      enzymes, even in 12 day old brain, increased rapidly, mainly in neocortical glial
      cells. In the corpus callosum enzymes were not significantly hyperactive before
      the light myelination stage. Some hyperactivity declined after 21 days. Oxidative
      processes and phosphate metabolism were most disturbed.

PMID- 4359162
TI  - Levo(-) amphetamine and dextro(+) amphetamine in the treatment of narcolepsy.
AB  - The narcoleptic syndrome is a life-long and sometimes familial disorder in which
      there is a disturbance of the rapid eye movement phase of sleep. Patients with
      periodic sleep in the daytime but no other symptoms seldom develop the
      narcoleptic syndrome and have a separate unrelated disorder. Twelve patients with
      the narcoleptic syndrome were treated separately with l(-) amphetamine and d(+)
      amphetamine. Both drugs abolished narcolepsy, d(+) amphetamine being slightly
      more potent than l(-) amphetamine. In equipotent doses, unwanted effects of
      nervousness and insomnia were equal in frequency. No tolerance to either
      preparation developed during a six month period. Cataplexy was not affected by
      amphetamine treatment, but was abolished in two patients when clomipramine was
      given together with either amphetamine.

PMID- 4359163
TI  - Sensory conduction in peroneal and posterior tibial nerves using averaging
      techniques.
AB  - A method of obtaining pure sensory nerve conduction velocities in the lower
      extremities is described. This involves the use of electronic summation (signal
      averaging). Potentials were obtained and velocities calculated from all normal
      subjects examined. In patients with peripheral neuropathies it was often possible
      to obtain nerve velocities with signal amplitudes as low as 0.1 MUV and these
      were often slower than those obtained from the normal subjects. The advantages
      and disadvantages of this method are discussed. It is of significant clinical
      value in that pure sensory nerve conduction velocities can be measured in the
      legs when this may be the only valuable parameter in the absence of motor
      involvement. In addition, investigation of neuropathies at an earlier stage of
      development and recovery may be facilitated. It is hoped that in the future this
      technique of obtaining low amplitude responses with an analogue averager can be
      incorporated with the more routine aspects of nerve conduction testing when
      clinically indicated.

PMID- 4359165
TI  - The glomus bodies ("paraganglia") of the human larynx.

PMID- 4359164
TI  - A study of the H-reflex by single fibre EMG.
AB  - The latency of consecutive H-reflex responses of single human triceps surae
      motoneurones varies up to 2,500 MUs. A large part of this variation was shown to
      occur at the synaptic transmission. A moderate increase in stimulus strength from
      the threshold value shortened the mean latency and reduced the latency variation,
      presumably as a result of spatial summation of excitatory inputs. Further
      increase to maximum strength lengthened the mean latency, increased the
      variation, and resulted in a dropping out of some responses which was not
      produced by collision by antidromic impulses. These effects are believed to be
      due to an active inhibition. Changes of the latency were also obtained by
      Jendrassik's manoeuvre and facilitatory and inhibitory conditioning stimuli.

PMID- 4359166
TI  - Studies on growth hormones.

PMID- 4359167
TI  - Adsorption and reactions of chitinase and lysozyme on chitin.

PMID- 4359168
TI  - Selective binding properties of vitamin D transport protein in chick plasma in
      vitro.

PMID- 4359170
TI  - Some observations on the reliability of REM variables.

PMID- 4359169
TI  - Awakening latency from sleep for meaningful and non-meaningful stimuli.

PMID- 4359171
TI  - Change in the activity of chemical mutagens during their interaction with seed
      metabolites.

PMID- 4359172
TI  - Nature of the spots produced on the bodies of female Drosophila melanogaster
      under the influence of methylmethane sulfonate.

PMID- 4359173
TI  - [Salivary gland tumors--synopsis of 692 cases].

PMID- 4359174
TI  - The effect of certain amino acids on reproduction of encephalomyocarditis virus.
      II. Investigation of the inhibiting effect of L-histidine.

PMID- 4359175
TI  - [Influence of medium osmolarity and ionic strength on virus reproduction in
      diploid and heteroploid cell cultures (author's transl)].

PMID- 4359176
TI  - [A latex agglutination test for typing enteroviruses (author's transl)].

PMID- 4359177
TI  - Sendai virus nucleocapsids in the nucleoli of infected cells.

PMID- 4359178
TI  - Altered cellular responses to interferon induction by poly I-poly C: priming and
      hyporesponsiveness in cells treated with interferon preparations.

PMID- 4359179
TI  - Foot-and-mouth disease: growth of virus after conjunctival inoculation of cattle.
      Brief report.

PMID- 4359180
TI  - The effect of D-thyroxine on the metabolism of cholesterol in familial
      hyperbetalipoproteinaemia.

PMID- 4359181
TI  - The very low density lipoproteins of cholesterol-fed rabbits. A study of their
      structure and in vivo changes in plasma.

PMID- 4359182
TI  - The effect of combined treatment with phenformin and stanazolol on blood lipids
      and fibrinolytic activity in patients with hypertriglyceridaemia.

PMID- 4359183
TI  - Clinical and metabolic effects of pentaerythritol tetranicotinate(Perycit)and a
      comparison with plain nicotinic acid.

PMID- 4359184
TI  - [Primary liver cancer in Viet-Nam].

PMID- 4359185
TI  - Reflections on possible mechanisms of action of anti-inflammatory drugs.

PMID- 4359186
TI  - Biochemical properties of a defective hamster C-type oncornavirus.

PMID- 4359187
TI  - A proposed regulator for poliovirus: the equestron.

PMID- 4359188
TI  - Total recovery of infectious virus from noninfectious type 1 poliovirus-antibody
      complex by heating in salts.

PMID- 4359189
TI  - Radioimmunoassay of avian RNA tumor virus group-specific antigen.

PMID- 4359190
TI  - Rapid diagnosis of enterovirus meningitis by immunofluorescent staining of CSF
      leukocytes.

PMID- 4359191
TI  - Observations on the rescue of simian virus 40 induced by cell fusion from
      heterokaryon cultures using electron autoradiography.

PMID- 4359192
TI  - Multiplicity reactivation in UV-irradiated herpes simplex type 1 virus.

PMID- 4359193
TI  - Deoxythymidine kinase from rabbit kidney cells infected with herpes simplex virus
      types 1 and 2.

PMID- 4359194
TI  - Thymidine kinase activity of herpes simplex virus temperature-sensitive mutants.

PMID- 4359195
TI  - Potentiation of effect of prolactin by adrenocorticotropic and growth hormones
      upon weight and nucleic acids contents of female rat mammary gland.

PMID- 4359196
TI  - Effect of various enzymes and chelating agents on SV40 tumor-specific
      transplantation antigens.

PMID- 4359197
TI  - Hodgkin's disease: involvement of viral agents in the etiology.

PMID- 4359198
TI  - Nuclear magnetic resonance study of the rate of electron transfer between
      cytochrome c and iron hexacyanides.

PMID- 4359199
TI  - Low resolution structure of adenylate kinase.

PMID- 4359200
TI  - Properties of the genome in experimental hepatomas: variations in the composition
      of chromatin.

PMID- 4359201
TI  - Lipids of cultured hepatoma cells. I. Effect of serum lipid levels on cell and
      media lipids.

PMID- 4359202
TI  - Lipids of cultured hepatoma cells. II. Effect of media lipids on cellular
      phospholipids.

PMID- 4359203
TI  - Alternate pathways of cerebroside catabolism.

PMID- 4359204
TI  - Immunochemical quantification of human plasma Lp(a) lipoprotein.

PMID- 4359205
TI  - Removal of lipid from intact erythrocytes and ghosts by aqueous solutions and its
      relevance to membrane structure.

PMID- 4359206
TI  - Ultrastructural findings in acrodermatitis enteropathica.

PMID- 4359207
TI  - Persistence of adenylate kinase and other enzymes in glycerol extracted muscle.

PMID- 4359208
TI  - The ultrastructure of a transplantable rat hepatoma induced by 3'-methyl-4
      dimethylaminoazobenzene.

PMID- 4359209
TI  - Enzymes of carbohydrate metabolism in rat hepatoma induced by 3'-methyl-4
      dimethylaminoazobenzene.

PMID- 4359210
TI  - Pyruvate and citrate concentrations in rabbit aqueous humour determined by an
      enzymatic procedure.

PMID- 4359211
TI  - NMR investigations of caffeine-sodium benzoate interactions.

PMID- 4359212
TI  - Ultrastructure of sarcoma 180 cells in mice treated with testosterone propionate.

PMID- 4359213
TI  - [The art of incisions by syndactyly-recidives (author's transl)].

PMID- 4359214
TI  - mRNA synthesis in erythropoiesis: specific effect of erythropoietin on the
      synthesis of DNA-like RNA.

PMID- 4359215
TI  - Messenger RNA processing in vertebrate cells.

PMID- 4359216
TI  - Reconstitution of 50S ribosomal subunits and the role of 5S RNA.

PMID- 4359217
TI  - Studies on HeLa cell nucleoli.

PMID- 4359218
TI  - Antibiotic action in protein synthesis.

PMID- 4359219
TI  - Modifications of polysome-associated RNA after poliovirus infection.

PMID- 4359221
TI  - Electrical activity in dissociated cell cultures from fetal mouse cerebellum.

PMID- 4359220
TI  - Synthesis of mitochondrial proteins.

PMID- 4359222
TI  - The role of norepinephrine in the function of the area postrema. II. In vitro
      incubation and stimulated release of tritiated norepinephrine.

PMID- 4359223
TI  - In vivo studies on the effect of 6-hydroxydopamine on amino acid metabolism in
      brain.

PMID- 4359224
TI  - The effect of mesencephalic reticular stimulation on intracellular potentials of
      cat lateral geniculate neurons.

PMID- 4359225
TI  - Brain stem stimulation and the hypothesis of presynaptic inhibition in cat
      lateral geniculate nucleus.

PMID- 4359226
TI  - The use of counter-current distribution to examine the effect of damaging agents
      on DNA.

PMID- 4359227
TI  - The biosynthesis and secretion of insulin.

PMID- 4359228
TI  - Insulin and insulin-like substances in the circulation.

PMID- 4359229
TI  - Respiratory function on asthmatic patients using beclomethasone dipropionate
      administered by pressurised aerosol.

PMID- 4359230
TI  - Enzymology of kidney tissue.

PMID- 4359232
TI  - Alkaline phosphatase activity in canine renal homografts.

PMID- 4359231
TI  - Enzymes and isoenzymes in urine.

PMID- 4359233
TI  - Neurologic examination.

PMID- 4359234
TI  - Absorption and secretion of salt and water by the small intestine.

PMID- 4359235
TI  - The manganous-adenosine triphosphate system. A reinvestigation of its proton
      magnetic resonance spectra.

PMID- 4359236
TI  - A 99mTc-pyrophosphate kit: a convenient, economical, and high-quality skeletal
      imaging agent.

PMID- 4359237
TI  - Ultracentrifugal studies with absorption optics and a split-beam photoelectric
      scanner.

PMID- 4359239
TI  - Magneto optical rotation spectroscopy.

PMID- 4359240
TI  - Study on tumour specific cell surface antigen in avian sarcoma virus-induced
      mammaliam cells with the aid of peroxidase-labelled antibody.

PMID- 4359238
TI  - Chromatography of proteins on hydroxyapatite.

PMID- 4359241
TI  - Electrophoretic properties of the product of protein synthesis in mitochondria of
      rat liver and Zajdela hepatoma.

PMID- 4359242
TI  - Fusion of XC rat sarcoma cells induced by murine leukaemia virus-infected mouse
      mammary tumour cells. Absence of interference by simultaneously synthesized
      mammary tumour virus.

PMID- 4359243
TI  - Herpesviruses from fish to man--a search for pathobiologic unity.

PMID- 4359244
TI  - Demyelinating diseases and certain virus infections.

PMID- 4359246
TI  - Growth kinetics of solid tumors.

PMID- 4359245
TI  - The relation between structure and function in mitochondria. Its relevance in
      pathology.

PMID- 4359247
TI  - [Existence of 2 types of cell in gamma tumors of the thyroid in the rat].

PMID- 4359249
TI  - Herpes simplex encephalitis. A report of three further cases.

PMID- 4359250
TI  - The immunizing effect of commercial pigeon pox vaccines on pigeons.

PMID- 4359248
TI  - Activity of hydrolytic enzymes in a case of subacute multiple sclerosis.

PMID- 4359251
TI  - Inefficacy of dietary deficiencies of vitamins A, D3 and riboflavin on the
      reproductive performance of mature cockerels.

PMID- 4359252
TI  - Plasma renin activity (PRA) in 89 patients on regular haemodialysis.

PMID- 4359253
TI  - Renal transplantation in children.

PMID- 4359254
TI  - Regulation of aldosterone in anephric man maintained with regular haemodialysis.

PMID- 4359255
TI  - The presence of glycogen synthase in preparations of platelet plasma membranes.

PMID- 4359256
TI  - [Corticotropin stimulation of the adrenal cortex in patients with Klinefelter's
      syndrome].

PMID- 4359257
TI  - [Hereditary galactokinase deficiency].

PMID- 4359258
TI  - [Pulmonary adenomatosis].

PMID- 4359259
TI  - [Ultrastructure of thyroid adenoma from Askanazy cells].

PMID- 4359260
TI  - [Detection of C-type oncornaviruses in cattle with spontaneous and experimentally
      induced lympholeukosis].

PMID- 4359261
TI  - [Effect of cytochrome C, galactose and uridine triphosphate on the growth of
      transplantable tumors].

PMID- 4359262
TI  - [Treatment of disseminated sarcomas of the soft tissues].

PMID- 4359264
TI  - Ultrastructure of the rat posterior pituitary gland and evidence of hormone
      release by exocytosis as revealed by freeze-fracturing.

PMID- 4359266
TI  - The terminal neuromuscular junctions of lower chordates.

PMID- 4359263
TI  - Histochemical changes in the digestive gland of Lymnaea truncatula infected with
      Fasciola hepatica.

PMID- 4359265
TI  - Adrenergic and cholinergic innervation of the turtle heart ventricle.

PMID- 4359267
TI  - The capillaries of the middle ear mucosa in the guinea pig. Ultrastructure and
      permeability.

PMID- 4359268
TI  - [Studies on the filter-chamber of Planococcus citri Risso (Insecta, Homoptera).
      Histochemistry and ultrastructure (author's transl)].

PMID- 4359269
TI  - [Investigations on the longitudinal growth of fish skeletal muscle (author's
      transl)].

PMID- 4359271
TI  - Environmental modifications for controlling acute respiratory disease.

PMID- 4359270
TI  - [A comparative investigation of the specific gravity of the peritumoral brain
      tissue in man (author's transl)].

PMID- 4359272
TI  - Experimental reovirus infection in monkeys. II. Serologic studies.

PMID- 4359273
TI  - The distribution of incubation periods of neoplastic diseases.

PMID- 4359274
TI  - Probable autosomal recessive inheritance in a family with Albright's hereditary
      osteodystrophy and an evaluation of the genetics of the disorder.

PMID- 4359276
TI  - Systemic eosinophilic infiltrative disease (SEIDI).

PMID- 4359275
TI  - The genetic structure of a tribal population, the Yanomama Indians. IX. Gene
      frequencies for 18 serum protein and erythrocyte enzyme systems in the Yanomama
      and five neighboring tribes: nine new variants.

PMID- 4359277
TI  - Epstein-Barr virus (EBV)-induced transformation of human lymphoid cells and
      immunosurveillance against lymphoma development.

PMID- 4359278
TI  - Comparison of the direct and indirect immunoferritin tagging of Sendai virus
      antigen.

PMID- 4359279
TI  - The comparative approach to physiological psychology.

PMID- 4359280
TI  - Optic nerve pit and associated coloboma with serous detachment.

PMID- 4359281
TI  - Plasma renin levels in the normal and anephric fetus at birth.

PMID- 4359282
TI  - Corticotrophin and cortisol concentrations in the plasma of the chronically
      catheterised sheep fetus.

PMID- 4359283
TI  - "Primary" pulmonary histiocytosis X.

PMID- 4359284
TI  - Prolonged respirator support for the treatment of intractable myasthenia gravis.

PMID- 4359285
TI  - 2,3-Diphosphoglycerate fluctuations in erythrocytes reflecting pronounced blood
      glucose variation. In-vivo and in-vitro studies in normal, diabetic and
      hypoglycaemic subjects.

PMID- 4359286
TI  - Ulceration of the colon associated with rheumatoid arthritis and steroid
      treatment: report of a case.

PMID- 4359288
TI  - Ascending connections of a midbrain auditory area in a crocodile, Caiman
      crocodilus.

PMID- 4359287
TI  - Immunoadjuvant activity of bacterial fractions on antibody-forming cells during
      the primary immune response period.

PMID- 4359289
TI  - Ascending connections of a thalamic auditory area in a crocodile, caiman
      crocodilus.

PMID- 4359290
TI  - Uses and abuses of corticosteroids.

PMID- 4359291
TI  - Partial hepatectomy in metastatic Wilms' tumor.

PMID- 4359292
TI  - Cancer in children with primary immunodeficiency diseases.

PMID- 4359293
TI  - Molecular weight determination of Sendai and Newcastle disease virus RNA.
AB  - The molecular weights of Sendai and Newcastle disease virus RNA were estimated by
      sedimentation in sucrose gradients and by length measurements in the electron
      microscope under both denaturing and nondenaturing conditions. Sedimentation
      analyses under denaturing conditions yielded molecular weight estimates of 2.3 x
      10(6) to 2.6 x 10(6), whereas length measurements yielded estimates of 5.2 x
      10(6) to 5.6 x 10(6) for both denatured and nondenatured viral RNA. It would
      appear that the conditions of denaturation used (99% dimethyl sulfoxide at 26 C,
      and reaction with 1.1 M formaldehyde for 10 min at 60 C) do not equally denature
      parainfluenza virus RNA and other RNAs, such as cellular rRNA, 45S rRNA
      precursor, and R17 RNA.

PMID- 4359294
TI  - Interactions of polyoma and mouse DNAs. I. Lytic infection of bromodeoxyuridine
      prelabeled mouse embryo cells.
AB  - On CsCl isopycnic centrifugation of the DNA extracted from secondary mouse embryo
      (ME) cultures grown in the presence of 5-bromodeoxyuridine (BUdR) and 5
      fluorodeoxyuridine (FUdR) for 40 h, 10 to 25% of the DNA was found to be
      unsubstituted, 70 to 80% was bromouracil-hybrid DNA, and 5 to 10% was heavy DNA.
      These results together with cell number determinations, autoradiography, and
      Feulgen microspectrophotometry revealed three types of cells in these cultures:
      (i) 60 to 80% of the cells replicated their DNA once, divided, and then stopped
      mitotic activity, (ii) 5 to 10% were going through a second round of DNA
      replication; whereas (iii) 10 to 30% did not replicate DNA during the BUdR-FUdR
      exposure. After the transfer of these cultures to normal medium (without BUdR
      FUdR), up to 20% of the cells resumed DNA synthesis asynchronously within 60 h,
      but no increase in cell number was observed. BUdR-FUdR-treated cultures, which
      were infected with polyoma virus in the absence of the thymidine analogues,
      supported a lytic infection to the same extent as did untreated ME cultures. This
      was concluded from the similar number of cells, which were induced to synthesize
      DNA, from the similar replication rate of the viral DNA, from the similar number
      of cells containing polyoma capsid proteins, and from the similar yields of
      progeny virus determined by hemagglutination and plaque formation. Thus, BUdR
      prelabeled ME cultures are suitable for the investigation of interactions of the
      polyoma and mouse genomes during the lytic infection.

PMID- 4359295
TI  - Interactions of polyoma and mouse DNA's. II. Polyoma-induced mouse DNA
      replication and pseudovirion formation.
AB  - Secondary mouse embryo (ME) cultures which had been grown prior to infection in
      the presence of 5-bromodeoxyuridine (BUdR) and 5-fluorodeoxy-uridine were found
      to be permissive for polyoma virus (16). The DNA extracted from the progeny virus
      yielded two bands on CsCl isopycnic centrifugation. The light band (LL) contained
      supercoiled circular (polyoma DNA I), open circular (polyoma DNA II), and linear
      (polyoma DNA III) molecules, as was seen by electron microscopy. The hybrid band
      (HL) contained exclusively linear molecules. This DNA was pure, density -
      labeled, pseudovirion DNA, i.e., fragmented HL mouse DNA. The quantitative
      comparison of HL and LL polyoma DNA III from six different virus preparations
      always revealed an excess of HL DNA, the ratio of HL/LL being between 1.2 and
      2.2. These results led to the conclusion that in BUdR-prelabeled, polyoma
      infected ME cells pseudovirion DNA is excised both from unreplicated and newly
      replicated regions of mouse DNA.

PMID- 4359296
TI  - Isolation and characterization of Sendai virus temperature-sensitive mutants.
AB  - Ten temperature-sensitive mutants of Sendai virus, a paramyxovirus, were isolated
      and partially characterized. The mutants replicated in chicken embryo lung cells
      at 30 C, but not at 38 C; wild-type virus grew equally well at both temperatures.
      Complementation tests divided the mutants into seven groups. Six groups
      synthesized neither infectious virus nor RNA when incubated at 38 C from the
      beginning of infection. Temperature shift-up experiments demonstrated that three
      of these complementation groups were blocked in early steps required for RNA
      synthesis, but these gene functions were not needed throughout the replicative
      cycle. In contrast, the other three RNA-negative complementation groups were
      defective throughout the replicative cycle in functions required for virus
      specific RNA synthesis. Only one mutant, which complemented all of the above,
      synthesized RNA but not infectious virus when placed at 38 C; the hemagglutinin
      of this mutant functioned only at the permissive temperature.

PMID- 4359297
TI  - Control of simian virus 40 gene expression in adenovirus-simian virus 40 hybrid
      viruses. Synthesis of hybrid adenovirus 2-simian virus 40 RNA molecules in cells
      infected with a nondefective adenovirus 2-simian virus 40 hybrid virus.
AB  - The effect of interferon on simian virus 40 (SV40) and adenovirus 2 (Ad2) T
      antigen synthesis has been examined in cells infected with SV40, with Ad2, and
      with a nondefective Ad2-SV40 hybrid virus, Ad2(+)ND(4). The induction of SV40 T
      antigen by SV40 was highly sensitive to interferon, whereas the induction of Ad2
      T-antigen by Ad2 was resistant. This difference in interferon sensitivity was
      also noted in cells simultaneously infected with both viruses. However, the
      induction of SV40 T antigen by Ad2(+)ND(4), which contains covalently linked SV40
      and Ad2 DNAs, was as resistant to interferon as the induction of Ad2 T antigen.
      This change in the interferon sensitivity of SV40 T antigen synthesis suggests
      that the expression of at least this portion of the SV40 genetic information in
      Ad2(+)ND(4) is under Ad2 genetic control. When RNA extracted from Ad2(+)ND(4)
      infected cells was examined by means of sequential hybridization with Ad2 DNA,
      elution, and rehybridization with SV40 DNA, 27% of the SV40-specific RNA was
      found to be linked to Ad2 RNA. No such linkage was detected in control mixtures
      of Ad2 and SV40 RNAs. The presence of Ad2 and SV40 nucleotide sequences in the
      same RNA molecule implies that, in Ad2(+)ND(4) infection, transcription is
      initiated in the DNA of one virus (Ad2 or SV40) and continues without
      interruption across the point of junction into the DNA of the other virus.
      Furthermore, the interferon resistance of Ad2(+)ND(4)-induced SV40 T antigen
      synthesis suggests that transcription of the genetic information for SV40 T
      antigen is initiated in a region of Ad2 DNA.

PMID- 4359298
TI  - Primate and murine type-C viral nucleic acid association kinetics: analysis of
      model systems and natural tissues.
AB  - Hybridization studies employing single-stranded (3)H-DNA transcripts of type-C
      viruses isolated from a woolly monkey or gibbon ape failed to detect nucleic acid
      sequences homologous to these viruses in the DNA from a variety of uninfected
      primate species. The possible significance of these results for the epidemiology
      of type-C viruses in primates is discussed.

PMID- 4359299
TI  - Virus replication in enucleate cells: vesicular stomatitis virus and influenza
      virus.
AB  - The requirement of the presence of a nucleus for the replication of vesicular
      stomatitis virus and influenza virus has been examined by following the growth
      and development of these viruses in enucleate BS-C-1 cells. Vesicular stomatitis
      virus replicates normally in enucleate cells with the rate of production of
      infectious virus, the amount of virus-specific protein synthesis, and the type of
      proteins produced being essentially the same in nucleate and enucleate cells.
      Influenza virus does not replicate in enucleate cells, no virus gene products can
      be detected, and there is no inhibition of cellular protein synthesis.

PMID- 4359300
TI  - Structure of the mouse mammary tumor virus: polypeptides and glycoproteins.
AB  - The polypeptide and glycoprotein compositions of the mouse mammary tumor virus
      virion from primary monolayer cultures of BALB/cfC3H mouse mammary tumor cells
      were studied by polyacrylamide gel electrophoresis by using internal and external
      labeling and Coomassie blue and periodic acid Schiff (PAS) staining. Twelve
      polypeptides were reproducibly resolved by the combined methods. Five major
      polypeptides were demonstrable with estimated molecular weights of 52,000,
      36,000, 28,000, 14,000, and 10,000. Seven minor polypeptides were also
      consistently detected and had estimated molecular weights of 70,000, 60,000,
      46,000, 38,000, 30,000, 22,000, and 17,000. Carbohydrate was associated with five
      of these polypeptides as measured by PAS stain or [(3)H] glucosamine labeling, or
      both. These glycoproteins had estimated molecular weights of 70,000, 60,000,
      52,000, 36,000 and 10,000. The majority of the PAS stain and glucosamine was
      found in the 52,000 and 36,000 dalton peaks.

PMID- 4359301
TI  - Phosphorylation of vesicular stomatitis virus in vivo and in vitro.
AB  - The structural protein, NS, of purified vesicular stomatitis virus (VSV) is a
      phosphoprotein. In infected cells phosphorylated NS is found both free in the
      cytoplasm and as part of the viral ribonucleoprotein (RNP) complex containing
      both the 42S RNA and the structural proteins L, N, and NS, indicating that
      phosphorylation occurs as an early event in viral maturation. VSV contains an
      endogenous protein kinase activity, probably of host region, which catalyzes the
      in vitro phosphorylation of the viral proteins NS, M, and L, but not of N or G.
      The phosphorylated sites on NS appear to be different in the in vivo and in vitro
      reactions, and are differentially sensitive to alkaline phosphatase. After
      removal of the membrane components of purified VSV with a dextran-polyethylene
      glycol two-phase separation, the kinase activity remains tightly associated with
      the viral RNP. However, viral RNP isolated from infected cells shows only a small
      amount of kinase activity. The protein kinase enzyme appears to be a cellular
      contaminant of purified VSV because an activity from the uninfected cell extract
      can phosphorylate in vitro the dissociated viral proteins NS and M. The virion
      associated activity may be derived either from the cytoplasm or the plasma
      membrane of the host cell since both of these cellular components contain protein
      kinase activity similar to that found in purified VSV.

PMID- 4359302
TI  - Murine virus-induced proteins synthesized by hamster tumor cells transformed by,
      but not producing, murine sarcoma virus.
AB  - The 8303 hamster tumor cells transformed by Moloney strain of murine sarcoma
      virus (M-MSV), but which do not produce virus, do contain murine virus-induced
      proteins. The virus-induced proteins within the cell were identified either as
      free proteins or in association with membranous material, including the plasma
      membrane. In addition, some were excreted by the 8303 hamster tumor cells into
      the growth medium. Most virus-induced proteins were larger than 68,000 daltons,
      and they did not dissociate into components of smaller size in the presence of
      detergent and a reducing agent. A small amount of virus-induced protein with a
      molecular weight of less than 20,000 was also found in the hamster tumor cells.
      No virus-specific proteins with the identical antigenic specificity or size of
      the major internal group specific antigen (molecular weight about 30,000) of the
      murine leukemia viruses were present in these cells. There is a common cell
      surface antigen present in three other tumor cell lines, both virus-producing and
      non-virus-producing, identical in reactivity to that of the murine virus-induced
      antigen of the 8303 hamster tumor cell. This antigen is not present on the cell
      surface of normal mouse embryo cells.

PMID- 4359303
TI  - Preliminary observations pertaining to polyadenylation of rhinovirus RNA.
AB  - Human rhinovirus type 14 contained polyadenylated RNA. Virus growth in HeLa cells
      was inhibited by cordycepin or polyuridilic acid and stimulated by polyadenylic
      acid. Polyadenylic acid also reversed cordycepin inhibition of virus-induced
      cytopathology of infected HeLa cells.

PMID- 4359304
TI  - Protein kinase associated with Sendai virions.
AB  - A protein kinase activity has been found associated with purified Sendai virions.
      Most of the virion proteins and exogenous protamine served as substrates for this
      enzyme.

PMID- 4359305
TI  - Proposal for numbering mutants of avian leukosis and sarcoma viruses.
AB  - A system for the numbering of mutants of avian sarcoma and leukosis viruses is
      proposed.

PMID- 4359306
TI  - Diagnosis of adrenal hypertensions.

PMID- 4359307
TI  - Augmentation of pressor response to exogenous renin in rats with acute mercuric
      chloride intoxication: failure to demonstrate renin activating princile (s) in
      plasma.

PMID- 4359308
TI  - Change in baroreceptor sensitivity by angiotensin.

PMID- 4359309
TI  - Metabolism of vasoactive substances in the lung.

PMID- 4359310
TI  - Effects of cyclic AMP and dibutyryl cyclic AMP on renin release in vivo and in
      vitro.

PMID- 4359312
TI  - Granular cell tumour in a male breast.

PMID- 4359311
TI  - Lysosomal enzyme activities in rat kidney treated with DOCA, especially with
      reference to renin, cathepsin and beta-glucuronidase.

PMID- 4359313
TI  - [EEG in infancy and early childhood].

PMID- 4359314
TI  - Formation of steroid conjugates in the human. I. Biosynthesis of uridine
      diphosphate glucuronic acid.

PMID- 4359315
TI  - Mechanism of action of glucocorticoids.

PMID- 4359316
TI  - Research still holds the answer.

PMID- 4359317
TI  - Extended observations on the secretion of an influenza virus inhibitor in the
      colostrum of a Caucasian donor.

PMID- 4359318
TI  - Effect of distilled water, hypertonic saline, freezing and freeze-drying on the
      haemagglutinin and haemolytic properties of Sendai virus.

PMID- 4359319
TI  - [Laboratory diagnosis in virus diseases].

PMID- 4359320
TI  - Editorial: Cat leukemia: a threat to man?

PMID- 4359321
TI  - [Stool examination with electron microscopy. Its value in the diagnosis of
      several viral infections].

PMID- 4359323
TI  - [Editorial: The etiological agent of infectious hepatitis is identified].

PMID- 4359322
TI  - [Millipore filter: 30 samples at a time].

PMID- 4359324
TI  - Case reports. Benign renal tumor in a 16-month-old boy treated with pre-operative
      radiotherapy.

PMID- 4359325
TI  - Restoration of the conversion of desmosterol to cholesterol in L-cells after
      hybridization with human fibroblasts.
AB  - Hybrids between different human cells (which synthesize cholesterol) and mouse
      cells (whose end-product of sterol synthesis is desmosterol) were analyzed for
      the ability to convert desmosterol to cholesterol. Conversion of
      [(14)C]desmosterol to cholesterol and incorporation of [(14)C]acetate into the
      end-product sterol were studied in the parental and hybrid cells. Concordant
      segregation of the conversion of desmosterol to cholesterol and the human
      chromosome F-20 was observed.

PMID- 4359326
TI  - Evidence that the AKR murine-leukemia-virus genome is complete in DNA of the high
      virus AKR mouse and incomplete in the DNA of the "virus-negative" NIH mouse.
AB  - The AKR mouse has a high titer of murine leukemia virus early in life, and virus
      negative cells derived from embryos of this mouse strain can be activated to
      yield murine leukemia virus by treatment with 5-iododeoxyuridine. In contrast to
      this high-virus strain, the NIH Swiss mouse has a low incidence of leukemia and
      no murine leukemia virus has been isolated from it (virus-negative). We have
      investigated this difference between AKR and NIH mice by examining the sequences
      specific for murine leukemia virus in nucleic acids of these mice. A single
      stranded viral-DNA probe synthesized in vitro using murine-leukemia-virus from
      the AKR mouse contains at least 87% of the sequences present in the 70S viral
      RNA; most of these sequences are in proportions similar to their content in the
      70S RNA. Using this probe in nucleic acid hybridization experiments, we have
      shown that NIH-mouse-cell DNA and AKR-mouse-cell DNA differ with respect to
      sequences specific for AKR murine-leukemia-virus: NIH-mouse-cell DNA lacks some
      of the virus-specific sequences present in AKR-mouse-cell DNA, and there are two
      distinct sets of virus-specific sequences in AKR-mouse-cell DNA, whereas there is
      only one set in NIH-mouse-cell DNA.RNA from virus-negative AKR-mouse cells grown
      in tissue culture contains some, but not all, virus-specific RNA sequences;
      however, within 48 hr after initiating treatment of these cells with 5
      iododeoxyuridine, the complete viral genome is represented in cellular RNA.

PMID- 4359327
TI  - Interruption of the sequential release of small and large molecules from tumor
      cells by low temperature during cytolysis mediated by immune T-cells or
      complement.
AB  - Specific lysis of tumor cells by thymus-derived lymphocytes from alloimmunized
      mice (T-effector specific lysis) was studied with target cells labeled with
      isotopes attached to both small ((14)C-labeled nicotinamide) and large ((51)Cr
      labeled) molecules. The results confirm and extend previous reports that target
      cells release small molecules considerably earlier than large molecules during T
      effector specific lysis. After interruption of T-effector specific lysis by
      specific antibody and complement directed against the killer cells, or by
      ethylenediaminetetraacetic acid, release of both isotopes continued, eventually
      reaching identical levels of specific release, the value of which represents the
      fraction of the target cell population which had been committed to die at the
      time these treatments were applied. On the other hand, release of both isotopes
      during T-effector specific lysis stops immediately when the cultures are cooled
      to 0 degrees . Thus, while ethylenediaminetetraacetic acid or specific complement
      mediated lysis of the killer cells merely prevents the initiation of any new
      damage to target cells, cooling to 0 degrees also stops the lytic process in
      already-damaged target cells. The colloid osmotic phase of target cell lysis
      induced by specific antibody and complement was similarly stopped at 0 degrees in
      tumor cells, but not in erythrocytes. Thus, in tumor target cells, both T
      effector specific lysis and complement cause a sequential release of
      progressively larger molecules which can be immediately stopped at any point by
      cooling to 0 degrees .

PMID- 4359328
TI  - Interferon induction by synthetic polynucleotides: importance of purine N-7 and
      strandwise rearrangement.
AB  - The antiviral activity and interferon-inducing ability of single-, double-, and
      triple-stranded polynucleotides, modified at pyrimidine C-5 or purine N-7, were
      evaluated in primary rabbit kidney cells challenged with vesicular stomatitis
      virus. (1) There is a parallel increase in antiviral activity and the temperature
      at which double-stranded polynucleotides rearrange to inactive triple-stranded
      complexes. (2) When the purine N-7 of (A)(n) is replaced by CH, all resulting
      double-stranded complexes fail to provide antiviral protection or to induce
      interferon, even though such complexes meet all requirements previously
      recognized for interferon induction. (3) Competition experiments between inactive
      and active polynucleotides indicate that single-stranded polynucleotides
      apparently do not bind to the cellular receptor sites for interferon induction,
      whereas triple-stranded complexes and inactive double-stranded complexes bind to
      such receptor sites but, probably for conformational reasons, fail to trigger the
      necessary message for interferon induction.

PMID- 4359329
TI  - Transformation of cultured mammalian cells by viable herpes simplex virus
      subtypes 1 and 2.
AB  - A continuous line of rodent cells carrying the genome of the Rous sarcoma virus
      was stably transformed by exposure to viable herpes simplex virus of either
      subtype 1 or 2. Transformation was accompanied by alteration of morphology,
      growth characteristics, acquisition of a thymidine kinase activity (EC 2.7.1.21)
      resembling the corresponding specific activity of the enzyme in the herpes
      simplex virus, and capacity to express continuously some antigens specific for
      herpes simplex virus.

PMID- 4359330
TI  - Collagen biosynthesis in nonfibroblastic cell lines.
AB  - Prolyl hydroxylase and other enzymes of collagen synthesis have been found in
      cloned cells, including epithelium, melanoma, liver, HeLa, pituitary, kidney, and
      neuroblastoma. The significance of collagen biosynthesis in nonfibroblastic cells
      lines is discussed.

PMID- 4359331
TI  - Effects of guanosine tetraphosphate, guanosine pentaphosphate, and beta-gamma
      methylenyl-guanosine pentaphosphate on gene expression of Escherichia coli in
      vitro.
AB  - The effects of guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate
      (pppGpp), both produced by E. coli, were measured on the activities of several
      genes in a cell-free system. Gene activity is measured as gene-directed synthesis
      of biochemically competent protein or transfer RNA. Both ppGpp and pppGpp
      stimulated the activities of the ara, lac, and trp operons and inhibited the arg
      operon. Production of transfer-RNA(Tyr) was unaffected by moderate levels of
      either ppGpp or pppGpp and only slightly inhibited at higher levels of ppGpp.
      Since the cell-free reaction mixtures hydrolyze pppGpp to ppGpp, we performed
      similar studies with a hydrolysis-resistant analog of pppGpp, the beta-gamma
      methylenyl derivative (pcppGpp). In general, pcppGpp shows the same inhibitory
      potency as pppGpp for the arg operon, but lacks the stimulatory effects on the
      ara, lac, and trp operons. This result suggests that the stimulation of these
      gene activities is specific for ppGpp.Under similar conditions, pppGpp and ppGpp
      show a slight inhibitory effect on the messenger-directed synthesis of beta
      galactosidase and no effect on the messenger-directed synthesis of MS2 viral-coat
      protein. These observations, together with the fact that in the same system these
      nucleotides affect coupled transcription and translation, lead us to surmise that
      the activities of pppGpp and ppGpp are exerted at the level of RNA polymerase
      activity.

PMID- 4359332
TI  - Penetration of mouse fibroblasts by the 5'-phosphate of 9-beta-D
      arabinofuranosyladenine and incorporation of the nucleotide into DNA.
AB  - 9-beta-D-Arabinofuranosyladenine 5'-monophosphate (araAMP) is more lethal to
      mouse fibroblasts (L cells) than the identical exogenous concentration of 9-beta
      D-arabinofuranosyladenine (araA) (Cancer Res. 32, 1512, 1972). [(3)H,(32)P]AraAMP
      (0.1 mM) was taken into L cells for 4 hr in the presence of a large excess of
      (32)P(i). The radioactivity was subsequently found mainly in the adenine
      nucleotides in the acid-soluble fraction and in the cell DNA. The cellular
      concentration of 9-beta-D-arabinofuranosyladenine 5'-triphosphate (araATP)
      exceeded 2 muM. More than 90% of the (3)H was associated with araA in the
      nucleotides. After degradation of the adenine-containing triphosphates with
      apyrase, the adenine mononucleotides were separated by thin-layer electrophoresis
      and chromatography. All of the (32)P and 97% of the (3)H were associated with
      araAMP. The small amounts of (3)H and (32)P in the acid-insoluble material were
      similar during a 4 hr incubation. The DNA fraction was degraded enzymatically to
      5'-mononucleotides. Both (32)P and (3)H were associated predominantly with 5'
      dAMP. Most of the (3)H was in araA, detected after dephosphorylation. Enzymatic
      degradation of the DNA fraction to 3'-mononucleotides and fractionation revealed
      (3)H primarily in the 3'-adenine nucleotide and (32)P in each of the
      deoxynucleoside 3'-monophosphates. After dephosphorylation of the 3'
      mononucleotides, 93% of the (3)H was found in araA. These results suggest that
      small amounts of araAMP penetrated the cell as an intact nucleotide, were further
      phosphorylated to the triphosphate, and subsequently incorporated in
      internucleotide linkage into DNA.

PMID- 4359333
TI  - ACTH antagonists.
AB  - Structural modifications within the active site of the ACTH molecule have
      produced analogs that inhibit the hormone sensitive adenylate cyclase system of
      bovine adrenal cortical plasma membranes. It is demonstrated that the tryptophan
      residue of the ACTH molecule is essential for stimulation of the enzyme.
      Substitution of tryptophan by phenylalanine or by N(alpha)-methyltryptophan as in
      [Gln(5), Phe(9)]corticotropin(1-20) amide or [N(alpha)-Metrp(9)]corticotropin(1
      24) provides ACTH analogs that exhibit high affinity for the ACTH receptor(s) but
      fail to activate the adenylate cyclase system. It is concluded that affinity for
      the receptors alone is not sufficient for expression of hormonal activity. The
      observation that adrenal cortical adenylate cyclase activated by fluoride ion is
      not inhibited by the antagonists indicates that hormonal and fluoride activation
      proceed via different mechanisms.

PMID- 4359334
TI  - Insulin-dependent regulation of insulin receptor concentrations: a direct
      demonstration in cell culture.
AB  - Chronic (5-16 hr) exposure of cultured human lymphocytes to 10(-8) M insulin at
      37 degrees in vitro produced a decrease in insulin receptor concentrations
      unaccounted for by simple occupancy of sites; acute exposure (0-2 hr) was without
      effect. These results reproduced observations in vivo where chronic
      hyperinsulinemia (e.g., 10(-8) M insulin in the circulation of obese
      insulinresistant hyperglycemic mice) is associated with a substantial reduction
      in the concentration of insulin receptors per cell, while acute hyperinsulinemia
      in vivo has no effect on receptor concentration. These data suggest a reciprocal
      relationship between insulin in the extracellular fluid and the concentration of
      insulin receptors per cell, which is mediated at the target cell itself by
      intracellular insulin-sensitive regulatory processes and directly affects target
      cell sensitivity to hormone.

PMID- 4359335
TI  - Kinetics of early changes in phosphate and uridine transport and cyclic AMP
      levels stimulated by serum in density-inhibited 3T3 cells.
AB  - A kinetic study of the early changes in uridine- and phosphate-transport rates
      and 3':5'-cyclic AMP levels induced by the addition of serum to quiescent 3T3
      cells revealed that the increase in phosphate uptake and the decrease in the
      intracellular concentration of 3':5'-cyclic AMP immediately follow the addition
      of serum. In contrast, the increase in uridine transport occurred after a lag of
      several minutes and was clearly preceded by the other changes. The activation of
      phosphate transport involved an increase in V(max), while a more complex pattern
      was observed for uridine transport. A possible role of phosphate in connection
      with the other early events was also studied. The addition of phosphate to
      quiescent cells produced a time-dependent decrease in 3':5'-cyclic AMP levels and
      this ion was required for full activation of uridine transport by serum. The
      results show that the increase in phosphate transport is a primary event in the
      reinitiation of growth and suggest that the increase in phosphate transport may
      be connected with subsequent metabolic steps.

PMID- 4359336
TI  - Peripheral versus central mechanisms accounting for antianxiety effects of
      propranolol.

PMID- 4359337
TI  - Granulocytes containing cytoplasmic inclusions in human tuberculous pleuritis.

PMID- 4359338
TI  - Nonhistone chromosomal proteins and gene regulation.
AB  - Evidence from several model systems suggests that nonhistone chromosomal proteins
      may regulate gene expression in eukaryotic cells. The data indicate that the
      synthesis of new species of nonhistone chromosomal proteins as well as
      modifications of preexisting nonhistone chromosomal proteins are involved in the
      control of transcription. However, from the vast number of proteins included in
      this class, it is apparent that, in addition to regulating the transcription of
      defined genome loci, the nonhistone chromosomal proteins include enzymes that
      have a general function, proteins that are involved in determining the structure
      of chromatin, as well as proteins that serve as recognition sites for binding of
      regulatory macromolecules. The presence of a nucleoplasmic pool of nonhistone
      chromosomal proteins which may exchange with the chromatin has also been reported
      (89). While it is clear that the nonhistone chromosomal proteins play a key role
      in the regulation of gene expression, the exact manner in which they interact
      with the genome to initiate, modify, or augment the transcription of specific RNA
      molecules remains to be resolved.

PMID- 4359339
TI  - Amorphous semiconductor switching in melanins.
AB  - Melanins produced synthetically and isolated from biological systems act as an
      amorphous semiconductor threshold switch. Switching occurs reversibly at
      potential gradients two to three orders of magnitude lower than reported for
      inorganic thin films, and comparable to gradients existing in some biological
      systems. Of a number of other biological materials tested, only cytochrome c
      acted similarly, but at the high potential gradients reported for thin film
      amorphous semiconductors.

PMID- 4359340
TI  - Hormonal control of neutrophil lysosomal enzyme release: effect of epinephrine on
      adenosine 3',5'-monophosphate.
AB  - Human neutrophilic leukocytes release neutral protease and beta-glucuronidase
      during cell contact with, and phagocytosis of, zymosan particles treated with
      rheumatoid arthritic serum. Release of lysosomal enzymes is inhibited by
      epinephrine and adenosine 3',5'-monophosphate (cyclic AMP), but not by
      phenylephrine or adenosine 5'-monophosphate. Inhibition of enzyme release by
      epinephrine may be mediated by cyclic AMP because the cyclic AMP in the
      neutrophils is increased by epinephrine treatment at the time when enzyme release
      is reduced.

PMID- 4359341
TI  - Hydrocortisone influences developing collaterals. 2. A cytochemical study.

PMID- 4359342
TI  - [Clinical significance of intrauterine infections].

PMID- 4359343
TI  - Clinical evaluation of the luteinizing hormone-releasing hormone (LH-RH) test in
      cases with anatomically verified disorders of the hypothalamo-pituitary region.

PMID- 4359344
TI  - A new sensor for pneumatic tonometry. Construction and working principle.

PMID- 4359345
TI  - Trabeculotomy ab externo.

PMID- 4359346
TI  - The heredity of glaucoma.

PMID- 4359347
TI  - Trabeculotomy, trabeculectomy and sinusotomy--some clinical results.

PMID- 4359348
TI  - Adrenalin therapy in glaucoma.

PMID- 4359349
TI  - Experience with keratoprostheses.

PMID- 4359350
TI  - Clinical and histological findings in crystalline corneal dystrophy.

PMID- 4359351
TI  - Ophthalmological involvements in diabetes. An introduction.

PMID- 4359352
TI  - Pregnancy and diabetic retinopathy.

PMID- 4359353
TI  - Pigment granules in iris pigment epithelium of diabetics.

PMID- 4359354
TI  - Follow-up of initially nonglaucomatous patients with fibrillopathia
      epitheliocapsularis (so-called senile exfoliation of the anterior lens capsule).

PMID- 4359355
TI  - The intraocular pressure. An introduction.

PMID- 4359356
TI  - Importance of callosal transfer in the extramacular inhibition phenomenon along
      the hemiopic border.

PMID- 4359357
TI  - Experiences in surgical treatment of haemorrhagic glaucoma. A follow-up study.

PMID- 4359359
TI  - Newer respiratory viruses: their role in respiratory illness of children.

PMID- 4359358
TI  - Reflex organization and contraction properties of facial muscles. An experimental
      study in the cat.

PMID- 4359360
TI  - [Study of the stability of sodium noramidopyrine methanesulfonate by gas
      chromatography].

PMID- 4359361
TI  - [Abnormal reaction of solvent in protometry of amines in acetic acid.
      Modification applied to cystine].

PMID- 4359362
TI  - [Alkaline phosphatase of a culture of Proactinomyces fructiferi var. ristomycini-
      producer of the antibiotic ristomycin].

PMID- 4359363
TI  - [Inhibition of multiplication of RNA-containing viruses in tissue culture by
      combined use of an interferon inducer and ribonuclease].

PMID- 4359366
TI  - Hepatoma in Papua New Guinea.

PMID- 4359365
TI  - Amyotrophic lateral sclerosis. Abnormal cellular inflammatory response.

PMID- 4359364
TI  - Human memory and the cholinergic system. A relationship to aging?

PMID- 4359367
TI  - Cutaneous amoebiasis.

PMID- 4359368
TI  - Assembly of tobacco mosaic virus rods in vitro. Elongation of partially assembled
      rods.

PMID- 4359369
TI  - Selenium as a catalyst for the reduction of cytochrome c by glutathione.

PMID- 4359370
TI  - Estrophilic binding sites of the uterus. Relation to uptake and retention of
      estradiol in vitro.

PMID- 4359371
TI  - Instability of the uterine estrogen receptor under in vitro conditions.

PMID- 4359372
TI  - Interaction of ovarian receptors with human luteinizing hormone and human
      chorionic gonadotropin.

PMID- 4359373
TI  - Excited states and reactivity of 5-deazaflavine. Comparative studies with
      flavine.

PMID- 4359374
TI  - Estimate of minimal distance between rapidly exchanging zinc and nucleotide
      binding sites in liver alcohol dehydrogenase.

PMID- 4359375
TI  - Deuterium isotope effects on initial rates of the liver alcohol dehydrogenase
      reaction.

PMID- 4359376
TI  - The function of the descending root of the fifth nerve.

PMID- 4359377
TI  - Cytoplasmic inclusions in the vermiform appendix and skeletal muscle in two types
      of so-called neuronal ceroid-lipofuscinosis.

PMID- 4359378
TI  - Evolutionary perspectives on the function of the optic tectum.

PMID- 4359379
TI  - Mouse leukemia virus growth in mouse cells contaminated with Mycoplasma.

PMID- 4359381
TI  - Effects of hexosamines and their acetyl derivatives on aggregation of rat
      hepatoma cells in rotation culture.

PMID- 4359382
TI  - Studies of initiation factors in protein synthesis of host liver and
      transplantable hepatoma.

PMID- 4359380
TI  - Isolation and chemical characterization of mucopolysaccharides from rat tumors.

PMID- 4359383
TI  - Two-dimensional gel electrophoresis of acid-extractable nuclear proteins of
      regenerating and thioacetamide-treated rat liver, Morris 9618a hepatoma, and
      Walker 256 carcinosarcoma.

PMID- 4359384
TI  - Recent studies on the formation of cerebrospinal fluid.

PMID- 4359385
TI  - Symmetrical epileptogenic foci in cerebral cortex of immature rat.

PMID- 4359386
TI  - Phenylalanyl-tRNA synthetase from Escherichia coli K10. Synergistic coupling
      between the sites for binding of L-phenylalanine and ATP.

PMID- 4359387
TI  - The wall peptidoglycans of Neisseria perflava, Moraxella glucidolytica,
      Pseudomonas alcaligenes and Proteus vulgaris strain P18.

PMID- 4359388
TI  - Products of mitochondrial protein synthesis in Neurospora crassa. Determination
      of equimolar amounts of three products in cytochrome oxidase on the basis of
      amino-acid analysis.

PMID- 4359389
TI  - The covalent structure of collagen. 1. The chymotrypsin, trypsin, and thermolysin
      derived peptides of alpha1-CB7 from calf-skin collagen.

PMID- 4359391
TI  - Cirrhosis and heterozygous FZ alpha1-antitrypsin deficiency in an adult. Case
      report and review of the literature.

PMID- 4359390
TI  - The covalent structure of collagen. 2. The amino-acid sequence of alpha1-CB7 from
      calf-skin collagen.

PMID- 4359393
TI  - Progressive enzyme studies on spontaneous hepatocarcinogenesis in reciprocal F1
      crosses of C3H (JAX) and ICRC strains.

PMID- 4359392
TI  - Mechanisms and control of secretion of bile water and electrolytes.

PMID- 4359394
TI  - Carcinoma of the lung--a correlative cytological and histopathological study.

PMID- 4359396
TI  - Melanoameloblastoma--report of a case and review of literature.

PMID- 4359395
TI  - Mixed salivary tumours.

PMID- 4359397
TI  - The application of ultrasound tomography in radiation therapy.

PMID- 4359398
TI  - A case report on calcified mucinous adenocarcinoma of the stomach.

PMID- 4359399
TI  - Renal hypertension in rats immunized against angiotensin I and angiotensin II.
AB  - Rats, actively immunized against angiotensin I (AI) and angiotensin II (AII),
      were subjected to unilateral renal artery constriction to determine whether the
      resulting hypertension, which may still ensue in the animal immunized against
      AII, could be prevented by such combined immunity. Sustained immunity to both AI
      and AII neither changed preoperative blood pressures of the rats from those of
      control mock-immunized rats nor altered the incidence or severity of renal dip
      hypertension. Vascular hyperresponsiveness to small quantities of free
      angiotensin could not be invoked to explain the hypertension, for there was no
      significant difference between mock-immunized hypertensive animals, and those
      remaining normotensive, regarding pressor sensitivity to intravenous AI, AII,
      renin, and norepinephrine. (AI + AII)-immunized hypertensive rats required AI
      doses averaging 260 times greater than nonimmune hypertensives to elicit
      equipressor responses, and were refractory to renin, but not to norepinephrine.
      Thus, while previous studies have not excluded direct participation of endogenous
      AI in renal clip hypertension in rats, evidence from our experiments makes it
      extremely difficult to sustain any pressor function therein for circulating AI or
      AII. Our results also preclude involvement of AII produced from circulating AI by
      conversion within arteriolar walls, close to receptor sites, since AI immunity
      would block this mechanism of action.

PMID- 4359401
TI  - Cell transformation by viruses and the role of viruses in cancer. The eleventh
      Marjory Stephenson Memorial Lecture.

PMID- 4359402
TI  - Cell-mediated immunity to herpes simplex virus in man.

PMID- 4359400
TI  - Genetic influences affecting the occurrence of a diabetes mellitus-like disease
      in mice infected with the encephalomyocarditis virus.
AB  - The M variant of encephalomyocarditis virus produces a diabetes mellitus-like
      disease in DBA/2 mice but not in animals of the C3H strain. Fewer than one-third
      of infected F(1) (DBA/2 x C3H) progeny exhibit the disease, whereas the
      prevalence in backcrosses (F(1) x DBA/2, F(1) x C3H) is comparable to the
      parental inbred strain. Thus, the mode of inheritance of the diabetic
      predisposition appears to be polygenic. DBA/2 animals develop striking
      inflammatory and necrotizing lesions of the islets of Langerhans; in contrast,
      alterations of the insular tissue in the C3H mice are minimal. Although metabolic
      abnormalities appear to be consequent to lesions of beta cells, the factors
      influencing the severity of these insular changes are incompletely understood.

PMID- 4359403
TI  - Guinea pig model for cutaneous herpes simplex virus infection.

PMID- 4359404
TI  - Viral studies in pemphigus.

PMID- 4359405
TI  - The mechanism of drug-induced erythrocyte vacuole formation.

PMID- 4359406
TI  - The influence of dietary potassium on the renin and aldosterone response to
      diuretic-induced volume depletion.

PMID- 4359407
TI  - Glomerular glycoprotein: galactosyl transferase activity in rat kidney.

PMID- 4359408
TI  - Lack of effect of erythropoietin on cyclic adenosine-3',5'-monophosphate levels
      in rat fetal liver cells.

PMID- 4359410
TI  - Autogenous immunity to endogenous RNA tumor virus: chronic humoral immune
      response to virus envelope antigens in B6C3F1 mice.

PMID- 4359409
TI  - Biologically active components from mycobacterial cell walls. II. Suppression and
      regression of strain-2 guinea pig hepatoma.

PMID- 4359411
TI  - Rat alpha1 fetoprotein. IV. Effect of growth and surgical removal of Morris
      hepatoma 7777 on the serum alpha1F concentration of Buffalo rats.

PMID- 4359412
TI  - Neoplastic transformation in vivo and in vitro of regenerating hamster hepatic
      cells by oncogenic DNA Simian virus 40.

PMID- 4359413
TI  - Differential inhibition by fucoses of aggregation of rat hepatoma cells in
      rotation-mediated cell cultures.

PMID- 4359414
TI  - Associations between tumor types in a large-scale carcinogenesis study of CF-1
      mice.

PMID- 4359416
TI  - Coexistence of particles resembling herpesvirus and type-C virus in feather
      follicle epithelium of chickens.

PMID- 4359415
TI  - Familial medullary thyroid carcinoma and pheochromocytoma: epidemiologic
      investigations.

PMID- 4359417
TI  - Development of leukemia in rats with tumors induced by chicken sarcoma virus.

PMID- 4359418
TI  - Sendai virion transcriptase complex: polyeptide composition and inhibition by
      virion envelope proteins.
AB  - Sendai virions, disrupted in 2% Triton X-100 in 1 M KCl, were separated into
      nucleocapsids and envelope proteins by centrifugation. The nucleocapsids,
      representing 46% of the virion proteins, had a buoyant density of 1.29 gm/cm(3)
      in D(2)O sucrose. RNA-dependent transcriptase activity associated with them had a
      ninefold greater specific activity than transcriptase assayed in unfractionated
      detergent-disrupted virions. These enzyme-active nucleocapsids contained only two
      polypeptides, the largest virion polypeptide (molecular weight 75,000) and the
      nucleocapsid structure unit (molecular weight 60,000). Virion envelope proteins,
      either glycoproteins or nonglycosylated matrix protein, inhibited nucleocapsid
      associated polymerase activity; brief heat denaturation abolished their
      inhibitory activity. Yeast RNA stimulated nucleocapsid-associated enzyme,
      suggesting that stimulatory polyanions act at the enzyme-template level.

PMID- 4359419
TI  - Protein kinase and phosphoproteins of vesicular stomatitis virus.
AB  - Protein kinases of similar but not identical activity were found associated with
      vesicular stomatitis (VS) virions grown in mouse L cells, primary chicken embryo
      (CE) cells, and BHK-21 cells, as well as being present in VS virions grown in
      HeLa and Aedes albopictus cells. The virion kinase preferentially phosphorylated
      the nucleocapsid NS protein in vitro and to a lesser extent the envelope M
      protein. Other virion proteins were phosphorylated in vitro only after drastic
      detergent treatment. Partial evidence that the virion kinase is of cellular
      origin was obtained by finding reduced enzyme activity in virions released from
      cells pretreated with actinomycin D and cycloheximide. Selective detergent and
      detergent-salt fractionation of VS virions revealed that the kinase activity was
      present in the envelope but not the spikes. The virion kinase activity in a
      Triton-salt-solubilized envelope fraction could be separated from M and G
      proteins and partially purified by phosphocellulose column chromatography.
      Virions released from L, CE, and BHK-21 cells infected in the presence of
      [(32)P]orthophosphate were labeled almost exclusively in the NS protein. Both
      soluble and nucleocapsid-associated NS phosphoprotein were present in cytoplasmic
      extracts of VS viral-infected L cells. The origin and function of the NS
      phosphoprotein remain to be elucidated.

PMID- 4359420
TI  - In vitro polyoma DNA synthesis: characterization of a system from infected 3T3
      cells.
AB  - A lysate from hypotonically swollen polyoma-infected BALB/3T3 cells incorporated
      labeled deoxynucleotide triphosphates into both viral and cellular DNAs. The
      incorporation was stimulated by the presence of ATP, deoxynucleotide
      triphosphates, thiols, and magnesium ions. Strong inhibition of incorporation was
      observed with thiol reagents and arabinosyl nucleotide triphosphates. The rate of
      in vitro synthesis increased with the temperature of incubation as expected.
      Incorporation into cellular DNA for up to 2 h was observed in lysates from virus
      infected and serum-stimulated cells but not from resting cells. Synthesis in the
      system, therefore, appeared to reflect the physiological state of the cells
      before preparation of the lysate. Incorporation into viral DNA stopped far sooner
      than that into cellular DNA. During the initial phase of the in vitro incubation,
      incorporation occurred into viral replicative intermediates (RI). These RIs had
      identical properties to those isolated after in vivo pulse labeling and a
      substantial proportion of them was matured to form I DNA at later times in the
      incubation through all the stages known to occur in vivo. Density labeling of the
      in vitro product showed that practically all of the RIs pre-existing in the
      infected cell took part in the in vitro reaction. Analysis of DNA labeled in
      vitro in the presence of 5-bromodeoxyuridine triphosphate showed that synthesis
      occurred on RIs at all stages of replication and that the progeny strands were
      elongated by up to 80% of unit viral DNA length. Pre-existing RIs, pulse labeled
      in vivo, showed evidence of a pool at a late stage of replication which required
      elongation of their progeny strands by approximately 25% during conversion to
      form I molecules. From density-labeling experiments, we were also able to show
      that viral DNA synthesis in vitro was semiconservative. The major reason for
      cessation of viral DNA synthesis in vitro was the very limited ability of the
      lysate to initiate new rounds of viral DNA synthesis.

PMID- 4359421
TI  - Virus type-specific thymidine kinase in cells biochemically transformed by herpes
      simplex virus types 1 and 2.
AB  - Transformation of mouse cells (Ltk(-)) and human cells (HeLa Bu) from a thymidine
      kinase (TK)-minus to a TK(+) phenotype (herpes simplex virus [HSV]-transformed
      cells) has been induced by infection with ultraviolet-irradiated HSV type 2 (HSV
      2), as well as by HSV type 1 (HSV-1). Medium containing methotrexate, thymidine,
      adenine, guanosine, and glycine was used to select for cells able to utilize
      exogenous thymidine. We have determined the kinetics of thermal inactivation of
      TK from cells lytically infected with HSV-1 or HSV-2 and from HSV-1- and HSV-2
      transformed cells. Three hours of incubation at 41 C produces a 20-fold decrease
      in the TK activity of cell extracts from HSV-2-transformed cells and Ltk(-) cells
      lytically infected with HSV-2. The same conditions produce only a twofold
      decrease in the TK activities from HSV-1-transformed cells and cells lytically
      infected with HSV-1. This finding supports the hypothesis that an HSV structural
      gene coding for TK has been incorporated in the HSV-transformed cells.

PMID- 4359422
TI  - Endogenous C-type viruses of BALB-c cells: frequencies of spontaneous and
      chemical induction.
AB  - A sensitive biological assay has been developed for studying the frequency of
      virus induction from mouse cells containing poorly infectious endogenous C-type
      viruses. A low spontaneous frequency of virus activation of one but not a second
      endogenous virus of BALB/c cells has been demonstrated. The resistance of BALB/c
      cells to superinfection by the more inducible virus appears to be absolute,
      whereas resistance to the other virus is only relative. Thus, the evidence
      indicates that the BALB/c cell exerts differential effects at two levels of
      regulation on the expression of its biologically distinguishable endogenous C
      type viruses.

PMID- 4359424
TI  - Protein kinase stimulated by cyclic GMP in uninfected and simian virus 40
      infected monkey kidney cells.
AB  - Uninfected African green monkey kidney cells contain a cyclic GMP-stimulated
      protein kinase. The level or specific activity of the enzyme was not
      significantly increased after infection of the cells with simian virus 40. This
      enzyme probably catalyzes the phosphorylation of the structural proteins of the
      virus.

PMID- 4359423
TI  - Biochemical studies on the chi mutation of bacteriophage T4: differential
      inhibition of chi+ and chi DNA synthesis by mitomycin C.
AB  - Biochemical studies were carried out to determine the effect of chi mutation on
      T4 DNA synthesis. The rate and final extent of DNA synthesis are almost the same
      with T4D- and T4chi-infected cells, although the burst size of T4chi is about one
      sixth that of the wild type. The DNA synthesis of T4chi-infected cells is more
      readily inhibited by mitomycin C than is that of T4 wild type. When mitomycin C
      was added during active phage growth, DNA synthesis of T4chi halted almost
      immediately. T4 DNA polymerases isolated from chi(+)- and chi-infected cells,
      however, exhibit no difference with regard to their sensitivities to mitomycin C,
      priming activities with alkylated or ultraviolet light-irradiated templates and
      other enzymatic properties.

PMID- 4359425
TI  - In vitro polyoma DNA synthesis: studies on an early temperature-sensitive mutant.
AB  - The polyoma ts-a function was investigated by using an in vitro DNA-synthesizing
      system. A comparison of systems derived from ts25 (a ts-a group mutant)-and
      ts1260 (a late group mutant)-infected cells showed that the activation energies
      for DNA chain elongation and the mechanisms of discontinous growth were identical
      for both mutants.

PMID- 4359426
TI  - Viruses of Entamoeba histolytica. V. Ultrastructure of the polyhedral virus V301.
AB  - The polyhedral amoebal virus V(301) presents sectioned profiles consistent with
      its having icosahedral (532) symmetry. The DNA appears to be packed in an
      orderly, folded arrangement of lesser symmetry.

PMID- 4359427
TI  - Detection of homologous RNA sequences among six rhabdovirus genomes.
AB  - Complete transcripts of the genome of vesicular stomatitis virus Indiana strain
      have been used to hybridize to virion RNA to determine if there is RNA sequence
      homology among these viruses. Cellular RNA from cells infected by each of these
      viruses has also been used for hybridization with the homologous or heterologous
      virion RNA. The results indicate that there is little exact sequence homology
      among these viruses.

PMID- 4359429
TI  - Analysis of minimal functions of simian virus 40. 3. Evidence for "host cell
      repair" of oncogenicity and infectivity of UV-irradiated simian virus 40.
AB  - The in vitro transforming capacity of simian virus 40 (SV40) for Syrian hamster
      cells is highly resistant to inactivation by UV light in comparison to
      infectivity. In the same cell system, we demonstrated a "host cell repair
      mechanism" sensitive to caffeine which is, to a large extent, responsible for the
      high resistance to UV inactivation of the transforming capacity of SV40. The
      survival of infectivity of UV-irradiated SV40 in CV-1 cells was also sensitive to
      caffeine, again indicating host cell repair. On the other hand, depression of
      normal cell DNA synthesis by hydroxyurea during the first 24 h postinfection only
      modestly reduced, and to a similar extent, the transforming capacity of UV
      irradiated and nonirradiated SV40.

PMID- 4359428
TI  - Location of the transcription defect in group I temperature-sensitive mutants of
      vesicular stomatitis virus.
AB  - The ribonucleoprotein-dependent RNA transcriptase in vesicular stomatitis B
      virions of four temperature-sensitive (ts) mutants belonging to complementation
      group I was analyzed in vitro at permissive (31 C) and restrictive (39 C)
      temperatures. The RNA-synthesizing activity of all four ts mutants was more
      labile at 39 C than was the transcriptive activity of wild-type (wt) virions. In
      order to locate the temperature-sensitive transcription defect in the mutants, wt
      and ts mutant virions were fractionated by Triton X-100-high salt solubilizer
      into a sedimentable ribonucleoprotein template and a nonsedimentable enzyme
      fraction, each of which alone had little or no transcriptive activity. The
      template- and enzyme-containing fractions of wt virions were then tested for
      their capacity to restore transcriptive activity at 39 C to corresponding
      template and enzyme preparations of ts mutant virions. Recombination of wt
      template and ts enzymes resulted in no significant restoration of capacity to
      synthesize RNA at restrictive temperature. In contrast, transcriptive function at
      39 C was reconstituted by recombining the wt enzyme with the template component
      of ts mutants. It appears, therefore, that the enzyme, rather than the template,
      is the temperature-sensitive component of the transcription complex of group I
      vesicular stomatitis virus mutants.

PMID- 4359430
TI  - Enzymatic radioiodination of the envelope proteins of avian myeloblastosis virus.
AB  - Purified avian myeloblastosis virus was iodinated by the lactoperoxidase method.
      Disruption of the labeled virions and chromatography of the viral proteins showed
      that radioiodine was associated only with the glycoproteins of the viral
      envelope. Reaction of the radiolabeled virus with antiviral antibody followed by
      mild detergent treatment and subsequent recovery of immune complexes showed this
      technique to be useful for the isolation of viral envelope antigens.

PMID- 4359433
TI  - Physiopathology of portal hypertension. Circulatory neophysiology after
      portacaval shunt.

PMID- 4359432
TI  - Regulation of expression of late genes of bacteriophage T5.
AB  - Amber mutants of bacteriophage T5 defective in gene C2 have been characterized.
      The product of this gene is required for the normal turn-on of synthesis of late
      RNA's and proteins, and, apparently, for the normal continued synthesis of early
      RNA's and proteins during late stages of infection. The inability of
      nonpermissive cells to synthesize any proteins, either late or early, during the
      late period after infection with a C2-mutant is not due to premature lysis of the
      infected cells, to a depletion of the cellular energy supply, or to degradation
      of phage DNA at late times. A possible role for the product of gene C2 in early
      and late transcription of the viral genome is suggested.

PMID- 4359434
TI  - Platelet function in hyperlipoproteinemia.

PMID- 4359431
TI  - Translation of vesicular stomatitis messenger RNA by extracts from mammalian and
      plant cells.
AB  - RNA was isolated from polyribosomes of vesicular stomatitis virus (VSV)-infected
      cells and tested for its ability to direct protein synthesis in extracts of
      animal and plant cells. In cell-free, non-preincubated extracts of rabbit
      reticulocytes, the 28S VSV RNA stimulated synthesis of a protein the size of the
      vesicular stomatitis virus L protein whereas the 13 to 15S RNA directed synthesis
      of the VSV M, N, NS, and possibly G proteins. In wheat germ extracts, 13 to 15S
      RNA also directed synthesis of the N, NS, M, and possibly G proteins. Analysis of
      extracts labeled with formyl [(35)S]methionine showed that the 28S RNA directed
      the initiation of synthesis of one protein, whereas the 13 to 15S RNA directed
      initiation of at least four proteins. It is concluded that the 28S RNA encodes
      only the L protein, whereas the 13 to 15S RNA is a mixture of species, presumably
      monocistronic, which code for the four other known vesicular stomatitis virus
      proteins.

PMID- 4359435
TI  - Biochemical studies on the regulation of myocardial contractility.

PMID- 4359437
TI  - Periodic acid-Schiff positive myeloblasts in chronic myelogenous leukaemia:
      relation to karyotype evolution.

PMID- 4359438
TI  - Pathology of gout.

PMID- 4359439
TI  - Pseudogout.

PMID- 4359441
TI  - [Pollution investigation of sandpits in Copenhagen. Fecal pollution illustrated
      with investigations of bacteria and eggs of intestinal worms].

PMID- 4359440
TI  - [Primary hyperparathyroidism. An analysis of 36 cases verified at operation].

PMID- 4359442
TI  - [Congenital viral infections].

PMID- 4359443
TI  - [(0)-forms of RNA-containing oncogenic viruses as a model of latent infection].

PMID- 4359444
TI  - [Study of the latent and chronic forms of cytomegalovirus infection in man].

PMID- 4359445
TI  - [Modeling chronic herpetic keratitis].

PMID- 4359446
TI  - [Angiography in glomus tumour (author's transl)].

PMID- 4359447
TI  - [Parotid surgery with special care of the facial nerve (author's transl)].

PMID- 4359448
TI  - [Effect of inhibitor Rc from rabbit reticulocytes on soluble and particular
      cytochrome oxidase of cattle heart mitochondria].

PMID- 4359449
TI  - Determinants for the establishment of permanent tissue culture lines from human
      gliomas.

PMID- 4359450
TI  - Comparative study of proteins, non-specific esterases and acid phosphatases in
      testicular fluids of different vertebrate species.

PMID- 4359451
TI  - [Behavioral and polygraphic study of 3 benzodiazepines and a barbiturate in the
      free implanted cat. Differentiation of the tranquilizing, sedative and hypnotic
      effects of these drugs in terms of their effects on the sleep-wakefulness cycle].

PMID- 4359452
TI  - [The problems of reentry, in the light of the experience at a post
      hospitalization facility].

PMID- 4359453
TI  - [Influence of 3 benzodiazepines and a barbiturate on the electroencephalogram
      during night sleep in man].

PMID- 4359455
TI  - Spontaneous rupture of hepatoma: a misdiagnosed surgical emergency.

PMID- 4359454
TI  - Hemangiopericytoma.

PMID- 4359456
TI  - The control of renal cortical perfusion by the renin angiotensin system.

PMID- 4359457
TI  - [Autoradiographic investigations on epidermal proliferation in male rats after
      cyproteronacetate administration (author's transl)].

PMID- 4359458
TI  - Comparative studies of synaptic membrane protein solubilization by chlorpromazine
      and sodium dodecylsulfate.

PMID- 4359460
TI  - The effect of gold salts on the purine:pyrophosphate phosphoribosyltransferase
      enzymes of human blood cells.

PMID- 4359459
TI  - The effect of gold salts on the biosynthesis of uridine nucleotides in human
      granulocytes.

PMID- 4359462
TI  - Levels of nucleoside and nucleotide kinases in rhesus monkey tissues.

PMID- 4359461
TI  - Effect of bioamines on the cellular differentiation of Hartmannella culbertsoni.

PMID- 4359463
TI  - Aspartate transcarbamylase from Streptococcus faecalis. Steady-state kinetic
      analysis.

PMID- 4359464
TI  - Allosteric and nonallosteric interactions with reduced nicotinamide adenine
      dinucleotide in two forms of cytoplasmic malic dehydrogenase.

PMID- 4359465
TI  - Identification of a distinction between cytoplasmic histone synthesis and
      subsequent histone deposition within the nucleus.

PMID- 4359467
TI  - Nasopharyngeal carcinoma (NPC). VI. Presence of an EBV nuclear antigen in fresh
      tumour biopsies. Preliminary results.

PMID- 4359468
TI  - Arterial hypertension in retrospect.

PMID- 4359466
TI  - Parsley plastocyanin. The possible presence of sulfhydryl and tyrosine in the
      copper environment.

PMID- 4359469
TI  - Choline acetyltransferase level in cyclic AMP and x-ray induced morphologically
      differentiated neuroblastoma cells in culture.

PMID- 4359471
TI  - Properties of arginine kinase from Drosophila melanogaster.

PMID- 4359470
TI  - Poly(adenosine diphosphoribose) polymerase in mammalian nuclei. Characterization
      of the activity in mouse fibroblasts (LS cells).

PMID- 4359472
TI  - Immunochemical studies on rat-liver microsomal NAD glycohydrolase.

PMID- 4359473
TI  - Fine structure of epithelial cell of secretory endometrium in unexplained primary
      infertility.

PMID- 4359474
TI  - Sperm transport through vas deferens: review of hypotheses and suggestions for a
      quantitative model.

PMID- 4359475
TI  - Interaction of bilayers with basic polypeptides. II. Interaction of phospholipid
      bilayers with copolymer L-lysine-L-phenylalanine.

PMID- 4359476
TI  - Studies on plasma membranes. XX. Sialidase in hepatic plasma membranes.

PMID- 4359477
TI  - Hierarchy levels in the control of blood flow to the hind limb of the dog. A new
      approach to the analysis of integrative neural cardiovascular control.

PMID- 4359478
TI  - Event train decoders with many inputs, pulse density versus momentaneous
      frequency.

PMID- 4359479
TI  - Considerations on models of movement detection.

PMID- 4359480
TI  - Equine infectious anemia.

PMID- 4359482
TI  - Breathing before birth in animals and man. An essay in developmental medicine.

PMID- 4359481
TI  - Drug therapy. Antacid therapy.

PMID- 4359483
TI  - [131I-labelled tumor-specific antibodies: a trials to concentrate radioisotoopes
      specifically in the tumor. II. The binding of 131I-labelled anti-human alpha
      fetoprotein antibody to the cultured human hepatoma cells].

PMID- 4359484
TI  - The central effects of thiopental and morphine in rats with renal hypertension.

PMID- 4359485
TI  - Characterization of a feedback-resistant phosphoribosylpyrophosphate synthetase
      from cultured, mutagenized hepatoma cells that overproduce purines.
AB  - A clone of cells in which the regulation of purine metabolism is genetically
      altered was selected and isolated from chemically mutagenized HTC cells (a line
      of rat hepatoma cells in continuous culture). The clone, designated MAU V, was
      selected for increased ability to salvage exogenous purines by isolating it in
      medium containing methylmercaptopurine ribonucleoside, adenine, and uridine, in
      which medium wild-type cells cannot divide. We have characterized these cells as
      having an increased rate of de novo purine biosynthesis, apparently as the result
      of an altered phosphoribosylpyrophosphate (PRPP) synthetase. The altered enzyme
      has normal catalytic properties but an altered sensitivity to feedback inhibition
      by purine and pyrimidine nucleotides. The types of inhibitions (competitive and
      uncompetitive) exerted by AMP, ADP, and TDP on the wild-type enzyme have been
      maintained in the altered enzyme, but values for K(i) have been increased by
      factors of 10, 17.5, and 5, respectively. The specific catalytic activities of
      AMP: pyrophosphate phosphoribosyltransferase and IMP:pyrophosphate
      phosphoribosyltransferase are normal. The mutant cell may serve as a model for a
      specific human disease, one type of dominantly inherited overproduction
      hyperuricemia.

PMID- 4359486
TI  - Studies on the orientation of cyclic AMP-dependent protein kinase in human
      erythrocyte membranes.
AB  - The topographic location of cyclic AMP-dependent protein kinase has been studied
      in preparations of permeable and sealed membranes derived from human
      erythrocytes. Both the catalytic and cyclic AMP-binding components of protein
      kinase are localized on the inner, cytoplasmic, surface of the plasma membrane.

PMID- 4359487
TI  - Temperature-dependent formation of dimers and oligomers of mitochondrial DNA in
      cells transformed by a thermosensitive mutant of Rous sarcoma virus.
AB  - In chick-embryo fibroblasts infected by T5, a temperature-sensitive mutant of
      Schmidt-Ruppin Rous sarcoma virus, the level of catenated dimeric and oligomeric
      mitochondrial DNA is temperature-dependent and correlates with the phenotypic
      manifestation of transformation. At the permissive temperature (36 degrees ),
      where transformation is expressed, the 2- to 3-fold elevated level characteristic
      of cells transformed by the wild-type Rous sarcoma virus was observed, but at the
      nonpermissive temperature (41 degrees ), at which cells appear normal and behave
      normally, the oligomer level was characteristic of uninfected cells. Temperature
      shifts from 41 to 36 degrees and vice versa resulted in phenotypic reversion and
      reversals of the respective levels of multiple-length DNA. Cellular growth rates
      were not altered. Treatment of control cells with cycloheximide resulted in a 5
      fold increase of oligomeric DNA, whereas exposure to 9-beta-D
      arabinofuranosyladenine had little effect. With both inhibitors, nuclear but not
      mitochondrial DNA synthesis was inhibited. The possible relation of formation of
      oligomeric mitochondrial DNA to alterations in the mitochondrial membranes of
      transformed cells and to inhibition of protein synthesis in the cytoplasm is
      discussed.

PMID- 4359488
TI  - Size and base composition of RNA in supercoiled plasmid DNA.
AB  - The average size and base composition of the covalently integrated RNA segment in
      supercoiled ColE(1) DNA synthesized in Escherichia coli in the presence of
      chloramphenicol (CM-ColE(1) DNA) have been determined by two independent methods.
      The two approaches yielded similar results, indicating that the RNA segment in CM
      ColE(1) DNA contains GMP at the 5' end and comprises on the average 25 to 26
      ribonucleotides with a base composition of 10-11 G, 3 A, 5-6 C, and 6-7 U.

PMID- 4359489
TI  - Phosphorylation of 5-bromodeoxycytidine in cells infected with herpes simplex
      virus.
AB  - 5-Bromodeoxycytidine is phosphorylated to 5-bromodeoxycytidine 5'-monophosphate
      in extracts of cells infected with herpes simplex virus but not in extracts of
      uninfected cells. The conversion of 5-bromodeoxycytidine to nucleotides and its
      utilization for DNA synthesis in uninfected cells occurs by deamination of 5
      bromodeoxycytidine to 5-bromodeoxyuridine followed by phosphorylation of 5
      bromodeoxyuridine to 5-bromodeoxyuridine 5'-monophosphate. In contrast, in cells
      infected with herpes simplex virus, 5-bromodeoxycytidine is phosphorylated
      directly to 5-bromodeoxycytidine 5'-monophosphate, which can then be deaminated
      to 5-bromodeoxyuridine 5'-monophosphate and incorporated into DNA. These results
      indicate a difference in the substrate specificity of nucleoside kinases induced
      by herpes simplex virus and the enzymes present in uninfected cells. It is
      suggested that this difference in substrate specificity between virus-induced and
      host-cell enzymes may allow selective chemotherapy of herpes simplex infections
      with 5-bromo- or 5-iododeoxycytidine.

PMID- 4359490
TI  - Interrelationship between adenylate cyclase activity, adenosine 3':5' cyclic
      monophosphate phosphodiesterase activity, adenosine 3':5' cyclic monophosphate
      levels, and growth of cells in culture.
AB  - To investigate how cell population density influences the intracellular
      concentration of cyclic AMP we have measured adenylate cyclase and cyclic AMP
      phosphodiesterase activities and cyclic AMP levels at various stages of cell
      density in normal rat-kidney (NRK) cells, which exhibit contact-inhibition of
      growth, and in normal chick-embryo fibroblasts (CEF), which do not show contact
      inhibition of growth under our conditions. Until NRK cells reach confluency, both
      activities increase with increasing cell population and cyclic AMP levels are
      low. As NRK cells reach confluency, cyclic AMP phosphodiesterase activity
      decreases somewhat whereas adenylate cyclase activity continues to rise. This
      increase in synthetic ability is accompanied by the increase in cyclic AMP levels
      which occurs in these cells at confluency. In CEF grown in 5% serum where density
      dependent inhibition of growth is not observed, both adenylate cyclase and cyclic
      AMP phosphodiesterase activities increase proportionately with increasing cell
      population density. No significant alteration occurs in the ratio between these
      two enzyme activities and no change is observed in cyclic AMP levels. The NaF
      stimulated activity in NRK cells increases with increasing cell density until the
      cells reach confluency; thereafter the NaF-stimulated activity remains constant.
      In contrast, the NaF-stimulated activity observed in CEF does not vary
      appreciably between light and heavy density. The observed changes in the enzymes
      of cyclic AMP metabolism accurately reflect the changes in cyclic AMP
      concentration as a function of cell population density. The data indicate that
      these two enzyme activities respond to increasing cell density to elicit a rise
      in intracellular cyclic AMP levels. The elevated cyclic AMP levels are thought to
      be involved in the regulation of cellular growth rate and the mediation of
      contact inhibition of growth.

PMID- 4359491
TI  - Regulation of cyclic nucleotide concentrations in photoreceptors: an ATP
      dependent stimulation of cyclic nucleotide phosphodiesterase by light.
AB  - Regulation of cyclic nucleotide concentrations in rod outer segments (Rana
      pipiens) has been further examined. The present studies show that illumination
      markedly diminishes the concentration of cyclic nucleotides in suspensions of
      photoreceptor membranes, but the locus of regulation is cyclic nucleotide
      phosphodiesterase (EC 3.1.4.c) (light-stimulated) and not adenylate cyclase.
      There is a marked disproportionality between bleaching of rhodopsin and
      stimulation of phosphodiesterase. Bleaching only 0.6% of the rhodopsin produces
      half the stimulation produced by bleaching 100% of the rhodopsin. The process of
      activation of phosphodiesterase by light is in two steps, a light-dependent step
      followed by an ATP-dependent step. Illumination (in the absence of ATP) produces
      a trypsin-resistant, heat-labile, macromolecular stimulator. In the presence of
      0.75 mM ATP (GTP or ITP) this stimulator produces a greater than 5-fold increases
      in the V(max) of photoreceptor phosphodiesterase without changing the K(m). At
      physiological substrate concentrations (10(-7) M) the rate of hydrolysis of
      cyclic GMP is 23 times greater than that of cyclic AMP. The light-produced
      stimulator appears unique to the photoreceptor membranes and does not activate
      phosphodiesterase in other tissues.

PMID- 4359492
TI  - Effects of bradykinin and indomethacin on cyclic GMP and cyclic AMP in lung
      slices.
AB  - Bradykinin, 1-100 mug/ml, produced a rapid rise in the concentration of 3':5'
      guanosine monophosphate (cyclic GMP) and 3':5'-adenosine monophosphate (cyclic
      AMP) in slices of guinea pig lung. Concentrations of both nucleotides reached a
      maximum in about 2 min, then declined to a basal levels in 6-12 min. The
      transient nature of the effect was presumbaly due to the rapid destruction of
      bradykinin as evidenced by (1) reaccumulation of nucleotides when bradykinin was
      added a second time, and (2) potentiation of the bradykinin effects by pyroGlu
      Lys-Trp-Ala-Pro, a peptide that inhibits inactivation of bradykinin by kininase.
      It has been reported elsewhere that histamine, prostaglandins E(1) and E(2), and
      beta-adrenergic stimulation can cause accumulation of cyclic AMP in lung slices
      without affecting cyclic GMP concentration, whereas acetylcholine increases the
      concentrations of both cyclic GMP and cyclic AMP. Thus it was possible that the
      effects of bradykinin were indirect, i.e., secondary to release of one or more of
      these compounds. Promethazine (an antihistamine), propranolol (a beta-adrenergic
      blocking agent) and atropine (an anticholinergic agent) did not alter basal
      cyclic nucleotide concentrations or the effects of bradykinin. Two inhibitors of
      prostaglandin synthesis, indomethacin and aspirin, which alone were without
      effect, in the presence of bradykinin completely prevented the rise in cyclic AMP
      but did not interfere with cyclic GMP accumulation. Similarly, the effect of
      acetylcholine on cyclic AMP was abolished by indomethacin while that on cyclic
      GMP was unaltered. We suggest that in lung and probably in other tissues,
      bradykinin, acetylcholine, and perhaps other stimuli enhance the synthesis and
      release of prostaglandins as one of the consequences of their effects on cyclic
      GMP metabolism.

PMID- 4359493
TI  - Properties of the beta nerve growth factor receptor of avian dorsal root ganglia.
AB  - Iodination of the beta nerve growth factor protein up to 4.1 iodines per mole of
      nerve growth factor was achieved with no loss of biological activity. At this
      level of incorporation no native or monoiodo nerve growth factor remained, the
      major species being the tri- and tetraiodo derivatives. An (125)I-labeled beta
      nerve growth factor of high specific activity containing 0.5 iodine per mole of
      beta nerve growth factor was used to determine the specific binding of nerve
      growth factor to dorsal root ganglion cells of 8-day-old embryonic chicks. The
      specific binding of (125)I-labeled nerve growth factor reached saturation at 30
      50 ng/ml and half-saturation at 7-8 ng/ml (0.26 nM). The number of receptors per
      responsive medio-dorsal cell was calculated to be about 2 x 10(4). The pattern of
      displacement of bound (125)I-labeled beta nerve growth factor by native beta
      nerve growth factor showed that the two proteins had identical affinities for the
      receptor. The specificity of the binding for beta nerve growth factor was
      demonstrated by the fact that only native beta nerve growth factor displaced the
      bound (125)I-labeled form. Partially inactivated derivatives of beta nerve growth
      factor retained the same fraction of their specific-binding capacity as of their
      biological activity. The specificity of the binding for cell type was shown by
      the lack of any specific component of (125)I-labeled beta nerve growth factor
      binding to liver or brain cells. The rate constant for association of beta nerve
      growth factor with its receptor, k(1), was 1.0 x 10(7) mol(-1) sec(-1) and the
      rate constant for dissociation, k(-1), 1.2 x 10(-8) sec(-1).

PMID- 4359495
TI  - [Comparative study of 35 cases of psoriasic pelvispondylitis paired with 35 cases
      of rheumatismal pelvispondylitis].

PMID- 4359494
TI  - The importance of calcium ions for the regulation of guanosine 3':5'-cyclic
      monophosphage levels.
AB  - Guanosine 3':5'-cyclic monosphosphate (cyclic GMP) levels in the ductus deferens
      of the rat were increased 2- to 3-fold by acetylcholine (10-1000 muM) or by 125
      mM KCl, while adenosine 3':5'-cyclic monophosphate (cyclic AMP) levels were not
      changed. After incubation for 30 min in the absence of Ca(++), cyclic GMP control
      levels were decreased by 85% and were not affected by acetylcholine or KCl. The
      readdition of Ca(++) (1.8 mM) for 3 min to Ca(++)-deprived tissue partially
      restored basal cyclic GMP levels and the effects of acetylcholine and KCl. The
      addition of Sr(++) (3.6 mM) or of Ba(++) (1.8 or 10 mM) also caused an increase
      in basal cyclic GMP in Ca(++)-deprived tissue. Cyclic AMP levels were not
      significantly changed under any of these conditions. The addition of the
      phosphodiesterase inhibitor, 1-methyl-3-isobutylxanthine (0.1 mM), to ductus
      deferentes increased the amount of cyclic AMP about 50% and that of cyclic GMP
      about 2-fold. The later effect also depended on the presence of Ca(++). 1-Methyl
      3-isobutylxanthine (0.1 mM) increased cyclic GMP and cyclic AMP levels in slices
      of rat submaxillary glands. Methacholine increased cyclic GMP if added in the
      presence of methyl isobutylxanthine. Cyclic GMP control levels and the effect of
      methyl isobutylxanthine were unchanged by Ca(++) omission, but the effect of
      methacholine was abolished.These findings indicate that calcium ions are
      important for the control of cyclic GMP levels in these tissues.

PMID- 4359496
TI  - [Paroxysmal nocturnal hemoglobinuria. Apropos of a case with morphological study
      of the erythrocytes].

PMID- 4359497
TI  - [Eosinophilia as an immune response. Reflections on 4 cases of penicillin allergy
      and 1 case of allergy to gold salts].

PMID- 4359499
TI  - [Reticulo-endothelial system and the mononuclear macrophage system].

PMID- 4359498
TI  - [Hypoglycemic accidents during treatment with antidiabetic sulfamides. Apropos of
      5 cases of hypoglycemic coma in aged subjects].

PMID- 4359500
TI  - [A case of congenital myopathy with mitochondrial abnormalities. Clinical and
      ultrastructural study].

PMID- 4359501
TI  - [Late sequelae and complications of gastrectomy. Preventive measures and
      treatment].

PMID- 4359502
TI  - Ultrastructure of herpes simplex virus infection of the nervous system of mice.

PMID- 4359504
TI  - Recurrent control from motor axon collaterals of Ia inhibitory pathways to
      ventral spinocerebellar tract neurones.

PMID- 4359503
TI  - Nerve biopsy findings in two cases of Tangier disease.

PMID- 4359506
TI  - Experimental and clinical oncology in People's Republic of China.

PMID- 4359505
TI  - Parallelism between mechanical and metabolic responses to cholecystokinin and
      prostaglandin E2 in extrahepatic biliary tract.

PMID- 4359507
TI  - An introductory note to ginseng.

PMID- 4359509
TI  - Endocrine dysfunction and anencephaly and spina bifida: an epidemiologic
      hypothesis.

PMID- 4359508
TI  - Anticancer Chinese herbal medicines.

PMID- 4359510
TI  - Rhinovirus infections in an industrial population. V. Change in distribution of
      serotypes.

PMID- 4359511
TI  - Effect of angiotensin II and its nonpressor derivatives on renin secretion.

PMID- 4359512
TI  - Effect of prostaglandins on renin reactivity.

PMID- 4359513
TI  - Angiotensin interaction with thirst mechanisms.

PMID- 4359514
TI  - Sympathetic cardiac stimulation in Bufo marinus under MS-222 anesthesia.

PMID- 4359515
TI  - Reticuloendotheliosis in a duck.

PMID- 4359516
TI  - Activation of volatile fatty acids in bovine liver and rumen epithelium. Evidence
      for control by autoregulation.
AB  - 1. The total capacities of homogenates of bovine liver and rumen epithelium to
      activate acetate, propionate and butyrate were determined. 2. Activating
      capacities were assayed by measuring the rate of formation of the corresponding
      CoA esters. The methods used for determining the concentrations of the CoA esters
      allowed the CoA esters of acetate, propionate and butyrate to be distinguished.
      It was thus possible to investigate the effect of the presence of a second
      volatile fatty acid on the rate at which a given volatile fatty acid was
      activated. 3. The propionate-activating capacity in rumen epithelium was
      decreased by about 87% in the presence of butyrate, the acetate-activating
      capacity in liver was decreased by about 55% in the presence of either propionate
      or butyrate, and the butyrate-activating capacity in liver was decreased by about
      40-50% in the presence of propionate. 4. All three activating capacities in liver
      appeared to be located in the mitochondrial matrix and membrane. The three
      activating capacities had similar locations to each other in rumen epithelium as
      well, although in this case activity was more evenly divided between the
      mitochondria and the cytoplasm. 5. The relative activating capacities towards the
      volatile fatty acids in the two tissues, together with the ability of one
      volatile fatty acid to inhibit the activation of another volatile fatty acid,
      appear to ensure that butyrate is mainly metabolized in the rumen epithelium and
      that propionate is metabolized in the liver.

PMID- 4359517
TI  - Mechanism of action of a microsomal inhibitor of protein synthesis potentiated by
      oxidized glutathione.
AB  - Extracts of microsomal fractions cause an inhibition of protein synthesis that is
      most pronounced in the presence of 0.1mm-GSSG and 0.01mm-GTP, and is abolished by
      thiol or 0.4mm-GTP (Scornik et al., 1967). Fractionation of microsomal extracts
      showed that this inhibition of protein synthesis was caused by an enzyme,
      nucleoside diphosphate phosphohydrolase. Direct inhibition of protein synthesis
      on detergent-treated polyribosomes by 0.1mm-GSSG was observed under conditions of
      GTP limitation induced by omission of a GTP-regenerating system, or addition of a
      nucleoside triphosphate diphosphohydrolase. Thus GSSG potentiated the inhibition
      of protein synthesis caused by an enzyme that promoted removal of GTP. The
      inhibition was abolished by adding 4mm-2-mercaptoethanol or 0.4mm-GTP. Nucleoside
      diphosphate phosphohydrolase was thought also to act by promoting removal of GTP,
      thus causing an inhibition of protein synthesis that was potentiated by GSSG.

PMID- 4359518
TI  - The effects of cytoplasmic extracts on DNA synthesis in vitro.

PMID- 4359519
TI  - Cross sensitivity to mono- and bifunctional alkylating agents of three radiation
      sensitive Saccharomyces mutants.

PMID- 4359520
TI  - Effects of storage conditons on survival and free radical populations in dried
      irradiated spores of Osmunda regalis.

PMID- 4359521
TI  - Application of electron spin resonance in research on mineralized tissues.

PMID- 4359522
TI  - Newer knowledge of chemotherapy in the treatment of tuberculosis of bones and
      joints.

PMID- 4359523
TI  - Idiopathic arthropathy of the elbow.

PMID- 4359524
TI  - The metabolism of biological alkylating agents.

PMID- 4359525
TI  - [Electromyography in the peripheral neurogenic syndrome].

PMID- 4359527
TI  - [Comparison of ACTH and insulin actions on sugar transport in their target
      organs].

PMID- 4359526
TI  - [Urinary hCG excretion patterns of patients with chorionic tumor during
      chemotherapy: indication of remission by chemotherapy].

PMID- 4359528
TI  - [A case of perianal Paget's disease].

PMID- 4359529
TI  - [Picture reports: Microsporia caused by Microsporum canis, milkers' nodule, skin
      and mucosal changes in monocytic leukemia, nevus cell nevus reaching into
      subcutaneous tissue on the haired scalp, with central Schridde's hair].

PMID- 4359530
TI  - [Glomus tumours of the middle ear (author's transl)].

PMID- 4359531
TI  - Isolation of temperature sensitive mammalian cells by selective detachment.

PMID- 4359532
TI  - A temperature-sensitive function in a Chinese hamster line affecting DNA
      synthesis.

PMID- 4359533
TI  - The importance of the techniques employed during the enzymatic preparation of
      isolated liver parenchymal cells.

PMID- 4359535
TI  - Deoxyglucose transport of uninfected, murine sarcoma virus-transformed, and
      murine leukemia virus-infected mouse cells.

PMID- 4359536
TI  - [Clostridium perfringens. 1. Experiments on the agglutination reaction].

PMID- 4359534
TI  - Changes in membrane transport function in G0 and G1 cells.

PMID- 4359537
TI  - Origin of esterified cholesterol transported in the very low density lipoproteins
      of human plasma.
AB  - In two subjects the specific activity of esterified cholesterol in plasma
      lipoprotein subfractions was measured for up to 9 hr after an intravenous
      injection of [(3)H]mevalonic acid. It was found to be consistently higher in
      larger (S(f) > 100) than in smaller (S(f) 20-100) very low density lipoproteins
      (VLDL). Four subjects were given an intravenous injection of heparin so that the
      VLDL could be studied as its concentration fell and subsequently rose again.
      During the first hour the relative reduction was greatest for triglyceride,
      intermediate for free cholesterol, and least for esterified cholesterol. Between
      1 and 7 hr postheparin, the VLDL pool was restored, but the pattern of increase
      of individual lipids was not parallel. The triglyceride increment was much
      greater during the 1-4-hr period than during the 4-7-hr period; in three of the
      subjects the free cholesterol increment was also greater during the earlier
      period. The increase in esterified cholesterol, however, was consistently greater
      during the 4-7-hr period. In six other subjects the specific activity of VLDL
      esterified cholesterol was related to that of its possible plasma precursors in
      samples collected at 1-hr intervals for 8 hr after the injection of
      [(3)H]mevalonic acid. Free cholesterol emerged as the most likely immediate
      precursor with the possibility of a hepatic as well as an intraplasma origin. The
      results did not support a major in vivo transfer of esterified cholesterol from
      high density lipoproteins to VLDL.

PMID- 4359538
TI  - Metabolism of sulfoquinovosyl diglyceride in Chlorella pyrenoidosa by
      sulfoquinovosyl monoglyceride: fatty acyl CoA acyltransferase and sulfoquinovosyl
      glyceride: fatty acyl ester hydrolase pathways.
AB  - Cell-free preparations of Chlorella pyrenoidosa catalyze the transfer of the
      fatty acyl moiety of fatty acyl CoA derivatives to sulfoquinovosyl monoglyceride
      to form sulfoquinovosyl diglyceride. This reaction is stimulated by Triton X-100
      concentrations of up to 0.6 mg/ml and has a pH optimum of 7.7. Similar Chlorella
      preparations catalyze the stepwise removal of both fatty acyl groups from
      sulfoquinovosyl diglyceride to form sulfoquinovosyl monoglyceride and then
      sulfoquinovosyl glycerol. This reaction is inhibited by both calcium and
      magnesium. The nonionic surfactant Triton X-100 inhibits the enzymatic
      deacylation at concentrations of less than 0.5 mg/ml but stimulates it at higher
      concentrations. The pH optimum for the deacylation of sulfoquinovosyl glycerides
      is 8.2, with little activity observed below pH 8. The enzymatic activities for
      both the transacylation and deacylation reactions are associated with a 30,000 g
      particulate fraction of Chlorella. Sulfoquinovosyl glycerol was found not to be
      an acceptor of the fatty acyl moiety of fatty acyl CoA derivatives. Methods are
      described for the preparation of sulfoquinovosyl monoglyceride, sulfoquinovose,
      and 3-sulfo-1,2-propanediol.

PMID- 4359539
TI  - Studies of glucagon resistance in large rat adipocytes: 125I-labeled glucagon
      binding and lipolytic capacity.
AB  - This study is concerned with potential modifications of large fat cells from
      adult rats (400-450 g) that make them resistant to stimulation by glucagon. The
      lipolytic capacity and (125)I-labeled glucagon-binding capability of these cells
      were compared with these properties of small glucagon-sensitive cells from young
      rats (130-160 g). As determined by maximal stimulation with theophylline,
      dibutyryl cAMP, or epinephrine, the lipolytic capacity of large cells was not
      markedly different from small cells, which suggests that an alteration
      contributing to glucagon insensitivity is not present in the enzymes involved
      with hormone-mediated lipolysis. Glucagon-binding studies did indicate a
      difference between the two cell types. Both large cells and particulate fractions
      from large cells bound less (125)I-labeled glucagon than small cells or small
      cell particles. That diminished binding is not a consequence of glucagon
      degradation is indicated by the similar amounts of (125)I-labeled glucagon
      degraded by both cell types. The decrease in (125)I-labeled glucagon binding was
      not as marked as the decrease in lipolytic response to glucagon stimulation. This
      lack of correlation and the relationship between elevated phosphodiesterase
      levels and glucagon insensitivity described in the accompanying report suggest
      that diminished binding explains only in part the marked resistance to glucagon
      found in large cells.

PMID- 4359541
TI  - Ultrastructural and physiological evidence for corticosteroid-induced alterations
      in hepatic production of very low density lipoprotein particles.
AB  - The cause of corticosteroid-induced hyperlipoproteinemia was studied in rats and
      mice. An ultrastructural morphometric method was utilized to demonstrate
      alterations in hepatocyte very low density lipoprotein content, and Triton WR
      1339-treated rats were used to identify changes in the removal of very low
      density lipoproteins from plasma. The results show that corticosteroid treatment
      results in (1) an increase in both plasma triglyceride and cholesterol levels,
      (2) an increase in rate of accumulation of triglyceride after inhibition of very
      low density lipoprotein removal by Triton, and (3) an increase in the number and
      size of Golgi-associated very low density lipoprotein particles in hepatocytes.
      These combined results suggest that corticosteroids induce hyperlipoproteinemia
      through increased hepatic production of very low density lipoproteins.

PMID- 4359540
TI  - Role of phosphodiesterase in glucagon resistance of large adipocytes.
AB  - The role of phosphodiesterase in glucagon resistance of large adipocytes was
      investigated. A comparison was made of phosphodiesterase activities of
      homogenates prepared from isolated small (mean diameter approximately 45 micro m)
      and large (mean diameter approximately 78 micro m) adipocytes, using various
      concentrations (5 x 10(-4) to 1 x 10(-7) M) of 3',5'-cAMP. Kinetic analyses
      revealed two distinct catalytic activities (high and low affinities) in both cell
      types; however, the activities of both high- and low-affinity enzymes were
      significantly elevated in large adipocytes. Lipolysis was measured in isolated
      adipocytes in the presence of different concentrations (0.1-0.6 mM) of the
      phosphodiesterase inhibitor aminophylline. Large adipocytes were less responsive
      to low levels of methylxanthine, suggesting that greater amounts of
      phosphodiesterase must be inhibited before lipolysis can be stimulated. To
      evaluate the influence of phosphodiesterase during glucagon-stimulated lipolysis,
      small and large adipocytes were incubated with a maximally effective
      concentration of glucagon (1.5 x 10(-6) M) in combination with various
      concentrations (0.1-0.6 mM) of aminophylline. Although the glucagon effect was
      potentiated in both cell types, the maximum lipolytic response of large
      adipocytes (at 0.4 mM aminophylline) was approximately 36% lower than that
      observed in small adipocytes (at 0.2 mM aminophylline). This reduction correlates
      closely with the decreased glucagon binding present in large cells; therefore, it
      appears that the glucagon-resistant state is adequately explained by elevations
      in phosphodiesterase levels and diminished glucagon-cell association.

PMID- 4359542
TI  - Changes of gangliosides and other lipids in skeletal muscle from rabbits with
      experimental dystrophy.
AB  - Comparison of the skeletal muscles from vitamin E-deficient and control rabbits
      showed that the muscles from the deficient animals had lower contents of protein
      and glycogen but more water and lipid. Increases of individual lipids per unit
      weight of muscle from deficient animals compared with those from control animals
      were 2.2-fold for gangliosides, 2.18-fold for cholesterol, 1.74-fold for
      sulfatides, and 1.45-fold for neutral glycosylceramides. Total phospholipids did
      not change; this was the result of an increase in sphingomyelin (1.47-fold) and a
      decrease of phosphatidylcholine to 83% of the control, while the other fractions
      remained unchanged. When the measurements were referred to total muscle, the
      contents of cholesterol, gangliosides, sulfatides, neutral glycosylceramides, and
      sphingomyelin in muscle from vitamin E-deficient rabbits were also above those of
      the control rabbits, and only the phosphatidylcholine content was decreased. It
      was not possible to determine whether the alteration of lipid content preceded or
      followed the onset of signs of muscular dystrophy.

PMID- 4359544
TI  - 13-Alkylpyrimidine nucleosides. Preparation and properties of 5-ethyl-2'
      deoxycytidine and related nucleosides.

PMID- 4359543
TI  - Synthesis and biological activity of 9-beta-D-arabinofuranosyladenine cyclic
      3',5'-phosphate and 9-beta-D-arabinofuranosylguanine cyclic 3',5'-phosphate.

PMID- 4359545
TI  - Angiotensin II analogs. 11. Further studies on des-aspartyl-angiotensin II.

PMID- 4359546
TI  - Antiviral agents. 1-Aralkyloxyadenosines.

PMID- 4359547
TI  - Phospholipases. I. Effect of n-alkanols on the rate of enzymatic hydrolysis of
      egg phosphatidylcholine.

PMID- 4359548
TI  - Phospholipases. II. Enzymatic hydrolysis of lecithin: effects of structure,
      cholesterol content, and sonication.

PMID- 4359549
TI  - The anatomy of the parotoid gland in Bufonidae with some histochemical findings.
      I. Bufo marinus.

PMID- 4359550
TI  - Carcinoma of the adrenal gland in children.

PMID- 4359551
TI  - Antipseudomonal effect of polymyxin and phenylethanol.

PMID- 4359552
TI  - Evidence for the action of d-lysergic acid diethylamide, mescaline and bufotenine
      on 5-hydroxytryptamine receptors in umbilical vasculature.

PMID- 4359553
TI  - The elimination of 5-hydroxyindoleacetic acid from cerebrospinal fluid:
      characteristics of the acid transport system of the choroid plexus.

PMID- 4359554
TI  - The effects of dibutyryl cyclic adenosine 3',5'-monophosphate, theophylline and
      aminophylline on neuromuscular transmission in the rat.

PMID- 4359555
TI  - Release of renal prostaglandin by catecholamines: relationship to renal endocrine
      function.

PMID- 4359556
TI  - Clostridium perfringens exotoxins. II. Purification and some properties of theta
      toxin.

PMID- 4359557
TI  - Establishment of two inbred strains of the rat for cancer research in tissue
      culture.

PMID- 4359558
TI  - [Zytogenetic examinations in malignant neoplasms of epithelial and mesenchymal
      origin].

PMID- 4359559
TI  - [Proceedings: Therapy of hemophilia A and B].

PMID- 4359560
TI  - [Gastric carcinoma revealed by ureteral metastasis].

PMID- 4359561
TI  - Salmonella typhimurium mutants affecting establishment of lysogeny.

PMID- 4359562
TI  - Interactions among genes controlling sensitivity to radiation and alkylation in
      yeast.

PMID- 4359563
TI  - Pathobiology of nucleocytoplasmic exchange.

PMID- 4359564
TI  - Intercellular junctions in normal and in malignant cells.

PMID- 4359565
TI  - Cellular DNA replication in viral infection.

PMID- 4359566
TI  - Viral and immunologic studies of human neoplasms.

PMID- 4359567
TI  - [Anatomo-clinical method in a clinical surgery service].

PMID- 4359568
TI  - [Successive bilateral cylindroma of the parotid].

PMID- 4359569
TI  - [Mammary and juxta-mammary tuberculosis].

PMID- 4359570
TI  - [Cancerization of an esophageal ulcer. Apropos of 2 cases of esophageal cancer
      developed on brachyesophagus, of which one presented a picture of degenerate
      ulcer].

PMID- 4359572
TI  - [Association of gastric cancer and tuberculosis].

PMID- 4359571
TI  - [Association of giant hypertrophic gastritis with stomach cancer and gastric
      polyposis].

PMID- 4359574
TI  - [Primary ulcers of the small intestine].

PMID- 4359573
TI  - [Cancer of the anastomoses of gastroenterostomy for ulcers].

PMID- 4359575
TI  - [Primary tumors of the small intestine. Apropos of 30 cases].

PMID- 4359576
TI  - [Ischemic colitis].

PMID- 4359577
TI  - [Aspecific pseudo-tumoral colitis of the right colon].

PMID- 4359578
TI  - [Association of sigmoid diverticulosis and cancer].

PMID- 4359579
TI  - [Para-rectal enteroid cyst].

PMID- 4359580
TI  - [Cystic forms of cancer of the liver].

PMID- 4359581
TI  - [Primary siphopathy and secondary lithiasis].

PMID- 4359582
TI  - [Inflammatory stenosis of the convergence of the right and left hepatic ducts].

PMID- 4359583
TI  - [Excreto-biliary carcinoma of the liver and left hepatic canal in primary chronic
      cholangitis].

PMID- 4359584
TI  - [Primary odditis without lithiasis or pancreatitis].

PMID- 4359585
TI  - [Chronic pancreatitis with circumscribed suppuration revealed by duodenal
      stenosis].

PMID- 4359586
TI  - [Willms tumor in an adult].

PMID- 4359587
TI  - ["Metastasizing adenoma" of the kidney].

PMID- 4359588
TI  - [Uterine tuberculosis in the aged woman].

PMID- 4359589
TI  - [Uterine sarcoma of the mulleroblastoma type].

PMID- 4359590
TI  - Arterial infusion chemotherapy of hepatoma.

PMID- 4359591
TI  - Thyroidography and thyrolymphography.

PMID- 4359592
TI  - [Dependence of KM and Vmax values upon the chain length of substrates for the
      reaction of yeast alcohol dehydrogenase].

PMID- 4359593
TI  - A myoelectric hand splint.

PMID- 4359594
TI  - Photo-affinity labelling of carbohydrate-binding sites in proteins: synthesis of
      potential inhibitors.

PMID- 4359596
TI  - [Effect of ACTH administration on pituitary-adrenocortical response after various
      forms of stress in animals].

PMID- 4359595
TI  - Isolation of an electrophoretically homogeneous glucomannan, using glutaraldehyde
      insolubilised concanavalin A.

PMID- 4359598
TI  - Sound deprivation causes hypertension in rats.

PMID- 4359597
TI  - Physiologic and pharmacologic roles for prostaglandins in obstetrics.

PMID- 4359599
TI  - Early stages in estrogen control of gene expression and its derangement in
      cancer.

PMID- 4359600
TI  - Microsomal membranes and the translational apparatus of eukaryotic cells.

PMID- 4359602
TI  - Virologic and immunologic aspects of major oral ulcerations.

PMID- 4359603
TI  - Rare combinations of multiple primary tumours: report of two cases.

PMID- 4359601
TI  - Solubilization and cellular fatty change.

PMID- 4359604
TI  - A child with multiple congenital malformations and a 46,XX,t(Bq+;Dq-)-45,XX,-B,
      D,+der(B),t(Bq+;Dq-) karyotype.

PMID- 4359605
TI  - Bilateral granular cell myoblastoma of the lip: report of case.

PMID- 4359606
TI  - [Adverse effects of corticosteroids and Cortrosyn depot in children with
      rheumatoid arthritis].

PMID- 4359607
TI  - Water insoluble and soluble glucans produced by extracellular
      glycosyltransferases from Streptococcus mutans.

PMID- 4359608
TI  - Influence of hormone therapy on rats treated with the carcinogen
      ethylmethanesulphonate.

PMID- 4359609
TI  - Analysis of morphophysiological developmental processes in mammalian brain.

PMID- 4359610
TI  - [Tumors of the cutaneous glomus].

PMID- 4359611
TI  - [Interest of the determination of lactic acid levels in the cerebrospinal fluid
      in the diagnosis of meningitis in adults].

PMID- 4359612
TI  - [Blood uric acid variations during acute respiratory decompensation in chronic
      bronchopneumopathy].

PMID- 4359613
TI  - [Obstructive complications of assisted ventilation using prolonged tracheal
      intubation or trachectomy. Prevention and supervision using systematic
      laryngoscopy. Apropos of 185 cases].

PMID- 4359615
TI  - [Traumatic herpes of the pinna].

PMID- 4359614
TI  - [Intraventricular meningioma in a family presenting Recklinghausen's disease].

PMID- 4359616
TI  - [Current views on the ultrastructure of some elements of the organ of Corti in
      mammals].

PMID- 4359617
TI  - [Treatment of late sequelae of Botkin's disease at the Anvakan health resort].

PMID- 4359618
TI  - [Bilateral Wilms' tumor in the adult (author's transl)].

PMID- 4359619
TI  - Clinical evaluations of a histologic examination of the side effects of
      myelographic contrast media.

PMID- 4359620
TI  - Endocrine pancreatic islet disease with diarrhea. Report of a case due to diffuse
      hyperplasia of nonbeta islet tissue with a review of 54 additional cases.

PMID- 4359622
TI  - The surgical treatment of occult insulinomas: a review of the problem.

PMID- 4359623
TI  - Preliminary experience of bone scanning with 99mTc-labelled polyphosphate in
      malignant disease.

PMID- 4359624
TI  - Antiviral antibody responses in patients with renal diseases.

PMID- 4359625
TI  - Morbidity and mortality in diabetics in the Framingham population. Sixteen year
      follow-up study.

PMID- 4359626
TI  - Further evidence for the pool function of ubiquinone as derived from the
      inhibition of the electron transport by antimycin.

PMID- 4359627
TI  - Structural properties of the creatine-kinase active site studied by chromophoric
      reagent labelling.

PMID- 4359628
TI  - Homology between enterotoxin protein and spore structural protein in Clostridium
      perfringens type A.

PMID- 4359629
TI  - Precursor--product relationship of encephalomyocarditis virus-specific
      polypeptides. Comparisons by tryptic peptide mapping.

PMID- 4359630
TI  - Purification, subunit structure and properties of two repressible
      phosphohydrolases of Bacillus subtilis.

PMID- 4359631
TI  - [The effect of increasing loads on adaptation to muscular activity].

PMID- 4359632
TI  - [Hypothalamo-hypophyseal response to electric stimulation of the olfactory
      nerve].

PMID- 4359633
TI  - [Study of somatotropin and corticotropin function with radioimmunological methods
      in primary hypothyroidism].

PMID- 4359634
TI  - [The behavior of LH gonadotropin in the metyrapone test].

PMID- 4359635
TI  - Studies of polymorphic traits for the characterization of populations. The
      populations of Scandinavia.

PMID- 4359636
TI  - Genetic polymorphisms in Finno-Ugrian populations. Finns, Lapps and Maris.

PMID- 4359638
TI  - Studies of polymorphic traits for the characterization of populations. African
      populations south of the Sahara.

PMID- 4359637
TI  - Investigation of genetic polymorphic traits in jews. A contribution to the study
      of population genetics.

PMID- 4359639
TI  - Polymorphic traits in peoples of Eastern Asia and the Pacific.

PMID- 4359640
TI  - Distribution of certain polymorphic traits in populations of the Indian peninsula
      and South Asia.

PMID- 4359641
TI  - Biochemical aspects of the pathogenesis of the thalassemia syndromes.

PMID- 4359642
TI  - Thalassemia types among Kurdish Jews.

PMID- 4359643
TI  - Globin synthesis in alpha- and beta-thalassemia.

PMID- 4359644
TI  - Mutations in the L-arabinose operon of Escherichia coli B-r that result in
      hypersensitivity to catabolite repression.
AB  - Two independent mutants resistant to l-arabinose inhibition only in the presence
      of d-glucose were isolated from an l-arabinose-sensitive strain containing the
      araD139 mutation. Preliminary mapping studies indicate that these mutations are
      closely linked to the araIOC region. Addition of d-glucose to growing cultures of
      these mutants results in a 95 to 98% repression of ara operon expression, as
      compared to a 50% repression of the parental control. Since cultures of both
      mutant and parental strains undergo a 50% repression of lac operon expression
      upon addition of glucose, the hypersensitivity to catabolite repression exhibited
      by these mutants is specific for the ara operon. Addition of cyclic adenosine
      monophosphate reverses the catabolite repression of the ara operon in both mutant
      and parent strains to 70 to 80% of the control. It is suggested that in these
      mutants the affinity of the ara operon initiator region for the cAMP-catabolite
      activator protein complex may have been altered.

PMID- 4359645
TI  - Cyclic adenosine 3',5'-monophosphate and morphogenesis in Mucor racemosus.
AB  - Yeastlike cells of Mucor racemosus grown under 100% CO(2) underwent morphogenesis
      to hyphae after exposure to air. The addition of dibutyryl cyclic adenosine
      monophosphate (dbcAMP) to yeastlike cultures inhibited this morphogenesis in
      media containing 2% glucose. The maintenance of uniformly spherical, budding
      cells required 1 mM dbcAMP in a defined medium containing Casamino Acids, and 3
      mM dbcAMP in a medium containing yeast extract and peptone. At these
      concentrations, dbcAMP also induced yeastlike development in young aerobic hyphae
      grown in media containing 2% glucose. Removal of dbcAMP resulted in hyphal
      development. The endogenous cyclic AMP (cAMP) content of yeastlike cultures was
      measured after a shift from CO(2) to air. A fourfold decrease in intracellular
      cAMP preceded the appearance of hyphal germ tubes. These results indicate that
      cAMP plays a role in the control of morphogenesis in Mucor racemosus.

PMID- 4359646
TI  - Derepressed levels of the isoleucine-valine and leucine enzymes in his T 1504, a
      strain of Salmonella typhimurium with altered leucine transfer ribonucleic acid.
AB  - A hisT mutant of Salmonella typhimurium was found to have altered regulation of
      the isoleucine-valine and leucine enzymes. These enzymes in the hisT strain were
      derepressed two- to eightfold over those of the parent wild-type strain when
      grown in minimal medium or under repressing conditions. The amount of tRNA(Leu)
      and the cellular concentration of charged tRNA(Leu) was about the same in the
      hisT strain and in the wild type. However, leucyl-tRNA from the mutant was
      chromatographically different from that of wild type, confirming previous reports
      that hisT strains have altered tRNA(Leu). These results suggest strongly that
      tRNA(Leu) is involved in repression of the isoleucine-valine and leucine enzymes
      in S. typhimurium.

PMID- 4359647
TI  - Isolation and complementation of mutants in galactose taxis and transport.
AB  - By using a new screening method, we have obtained 43 new Escherichia coli mutants
      defective in ring formation on galactose swarm plates, which score for defects in
      chemotaxis or transport. They were complemented and compared with mutations
      previously known to lie in the galactose-binding protein or the beta
      methylgalactoside (mgl) permease, or both. The mutations were all found to lie in
      three genes, called mglA, mglB, and mglC. mglB codes for the gene specifying the
      binding protein. Based on co-transduction experiments, mglA, mglB, and mglC lie
      close to each other on the bacterial chromosome.

PMID- 4359648
TI  - Properties of mutants in galactose taxis and transport.
AB  - beta-Methylgalactoside (mgl) permease mutants of Escherichia coli, which are
      defective in three genes, mglA, mglB, and mglC, were assayed for galactose taxis
      and galactose transport. The mglB product is the galactose-binding protein.
      Previous evidence, supported by our new findings, shows that the galactose
      binding protein is the recognition component for galactose taxis as well as for
      galactose transport. Most mutants defective in mglB showed strong effects on both
      chemotaxis and transport; however, a couple showed effects chiefly on one process
      or the other, thus allowing a separation of chemotaxis and transport. The mglA
      and mglC products have not yet been identified, but they must be components of
      the galactose transport machinery since mutants defective in mglA or mglC, or
      both, showed strongly reduced transport. Although some of these mutants showed
      little chemotaxis, most gave close to wild-type chemotactic responses. Thus,
      transport is not required for galactose taxis. The bacteria detect changes in the
      fraction of binding protein associated with galactose, not changes in the rate of
      transport.

PMID- 4359649
TI  - Ethylene glycol-induced alteration of conidial germination in Neurospora crassa.
AB  - In nutrient medium containing 3.22 M ethylene glycol or glycerol, conidia of
      Neurospora crassa grow as single cells, without forming the germ tubes
      characteristic of normal morphological germination. Ethylene glycol is more
      effective than glycerol in producing this response. After growth in ethylene
      glycol medium for a suitable time, the cells are easily disrupted by an abrupt
      decrease in osmotic pressure. Osmotic disruption yields intact nuclei and
      mitochondria, although mitochondrial fractions obtained in this way show
      significantly reduced concentrations of cytochromes c + c(1), as compared to
      those observed for comparable fractions obtained from vegetative hyphae. Cell
      cultures gradually adapted to lower concentrations of the glycol show a much
      higher degree of synchrony in the formation of germ tubes than do untreated
      conidia.

PMID- 4359650
TI  - Residual polarity and transcription-translation coupling during recovery from
      chloramphenicol or fusidic acid.
AB  - Fusidic acid or chloramphenicol was used to inhibit peptide synthesis to 1% of
      normal in Escherichia coli B, strain AS19. After 10 min of inhibition, peptide
      synthesis could be quickly restored to 80% of the normal rate after washing the
      bacteria on a filter. However, even in the presence of adenosine 3'-5'-cyclic
      monophosphoric acid to block catabolite repression, beta-galactosidase, the first
      enzyme of the lactose operon (lac), could only be induced to 10% of normal, and
      the last enzyme of the operon, galactoside acetyltransferase, even less. The
      first and last enzymes of the operon for tryptophan synthesis could be
      derepressed to about 30% of normal. The lac ribonucleic acid (RNA) induced during
      recovery showed a smaller than normal size distribution on sucrose gradients. The
      operator-proximal or -distal parts of this RNA were specifically labeled.
      Hybridization to phi80dlac deoxyribonucleic acid (DNA) suggested that although
      the distal parts of the lac RNA were barely detectable, initiation was occurring
      at normal rates in recovery. Either normal levels of distal messenger RNA (mRNA)
      are made but then rapidly degraded or the mRNA is not completed. The small amount
      that is made decayed abnormally slowly, probably as a result of slower
      transcription. Total mRNA decay was multiphasic with all components decaying
      slower than normal. We propose that there is a residual level of inhibition of
      peptide synthesis during recovery. The probability that a ribosome is blocked at
      any codon can be estimated from the data. The longer the message, the less likely
      its complete translation. We propose that the RNA polymerase can transcribe
      translatable mRNA for only a finite distance beyond the lead ribosome. Because
      ribosomes can load at the start of each message in a polycistronic mRNA, the
      probability that a distal message will be synthesized and translated is a
      function of the number of more proximal messages and the distances between their
      ribosome-loading sites.

PMID- 4359651
TI  - Genetic control of the 2-keto-3-deoxy-d-gluconate metabolism in Escherichia coli
      K-12: kdg regulon.
AB  - 2-Keto-3-deoxy-gluconate (KDG), an intermediate of the hexuronate pathway in
      Escherichia coli K-12, is utilized as the sole carbon source only in strains
      derepressed for the specific KDG-uptake system. KDG is metabolized to pyruvate
      and glyceraldehyde-3-phosphate via the inducible enzymes KDG-kinase and 2-keto-3
      deoxy-6-phosphate-gluconate (KDPG) aldolase. However, another inducible pathway,
      where the KDG is the branch point, has been demonstrated. Genetic studies of the
      KDG degradative pathway reported in this paper led to the location of KDG kinase
      negative and pleiotropic constitutive mutations. The kdgK locus, presumably the
      structural gene of the kinase, occurs at min 69 and is co-transducible with xyl.
      The mutants, simultaneously constitutive for the uptake, kinase, and aldolase,
      define a kdgR locus at min 36 between the co-transducible markers kdgA and oldD.
      As to the nature of the control exerted by the kdgR product, we have shown the
      following. (i) Thermosensitive mutants of the kdgR locus are inducible at low
      temperature but derepressed at 42 C for the three operons-kdgT (transport
      system), kdgK, and kdgA (KDPG aldolase). (ii) The kdgR(+) allele is dominant to
      the kdgR constitutive allele. (iii) A deletion in kdgA extending into the
      regulatory gene, kdgR, leads to a constitutive expression of the nondeleted
      operons-kdgT and kdgK. These properties demonstrate that the kdg regulon is
      negatively controlled by the kdgR product. It is presumed that differences in
      operator and in promotor structures could explain the strong decoordination,
      respectively, in the induction and catabolic repression, of these three enzymes
      activities.

PMID- 4359652
TI  - Binding of streptococcal competence factor by the spheroplast membrane of a group
      H streptococcus.
AB  - The binding of streptococcal competence factor (CF) was found to be specific for
      a strain of streptococcus which was capable of undergoing competence induction.
      Three other streptococcal strains which could not be induced to competence, did
      not bind CF. CF binding was independent of time, temperature, age of the culture,
      and type of growth media employed. Several observations indicated that the
      receptor sites for CF are located in the bacterial membrane: (i) the retention of
      CF by spheroplasts, (ii) the binding of CF by isolated membrane fractions, and
      (iii), the degradation of CF binding capacity of membranes by different chemicals
      and enzymes.

PMID- 4359653
TI  - Histidyl-transfer ribonucleic acid synthetase in positive control of the
      histidine operon in Salmonella typhimurium.
AB  - Histidyl-transfer ribonucleic acid (tRNA) synthetase (HRS), coded by the hisS
      gene, appears to play two roles in regulation of the histidine operon of
      Salmonella typhimurium: (i) in synthesis of a critical effector molecule,
      histidyl-tRNA, and (ii) a more direct effect elicited by the presence of the
      enzyme protein itself. The specific activity of HRS was elevated either by
      mutations in the strB locus or in hisS(+) merodiploids of Escherichia coli/S.
      typhimurium and S. abony/S. typhimurium. In each case, an increase in HRS was
      accompanied by an increase in histidine operon expression, indicating that HRS
      may be involved in positive control of the histidine operon. It is unlikely that
      HRS leads to increased histidine operon expression merely by acting as a "sponge"
      for charged tRNA. Rather, HRS appears to influence operon expression by
      interaction with some effector molecule other than charged tRNA or by a direct
      interaction with the histidine operator-promoter region. The functional level of
      histidine operon expression has no effect on HRS specific activity.

PMID- 4359654
TI  - Studies of respiratory components and oxidative phosphorylation in mitochondria
      of mi-1 Neurospora crassa.
AB  - Oxidative phosphorylation has been demonstrated with mitochondria of the mi-1
      respiratory mutant of Neurospora crassa. The P/O ratios observed with these
      mitochondria were approximately 0.8 with citrate and 0.4 with either externally
      added reduced nicotinamide adenine dinucleotide (NADH), succinate, or ascorbate
      tetramethyl-p-phenylenediamine (TPD). These P/O ratios suggest that there are
      only two sites of phosphorylation in mitochondria isolated from young (20 to 24
      h) cultures of the mi-1 mutant. The energy-dependent reduction of NAD(+) with
      succinate and the phosphorylation associated with ascorbate-TPD oxidation
      indicate that the first and the third sites of energy coupling are present in
      this mutant. Difference spectra of mitochondria from young cultures of the mi-1
      mutant revealed the presence of cytochrome c. Cytochromes b and a + a(3) were not
      detected. However, in the presence of antimycin A, a small peak in the Soret
      region at 430 nm was observed. A carbon monoxide difference spectrum revealed the
      presence of a component of the respiratory chain with a spectrum similar to that
      of cytochrome o. It is of interest that respiratory inhibitors such as antimycin
      A, 2-n-nonylhydroxyquinoline N-oxide, and cyanide abolished phosphorylation but
      only partially inhibited oxidation. It is postulated that the mi-1 respiratory
      system contains two pathways of electron transport-the first is associated with a
      phosphorylating pathway, whereas the second is a non-phosphorylating electron
      transport pathway.

PMID- 4359655
TI  - D-lysine catabolic pathway in Pseudomonas putida: interrelations with L-lysine
      catabolism.
AB  - The isolation of several mutant strains blocked in l-lysine degradation has
      permitted an assessment of the physiological significance of enzymatic reactions
      related to lysine metabolism in Pseudomonas putida. Additional studies with
      intact cells involved labeling of metabolic intermediates from radioactive l- or
      d-lysine, and patterns of enzyme induction in both wild-type and mutant strains.
      These studies lead to the conclusions that from l-lysine, the obligatory pathway
      is via delta-aminovaleramide, delta-aminovalerate, glutaric semialdehyde, and
      glutarate, and that no alternative pathways from l-lysine exist in our strain. A
      distinct pathway from d-lysine proceeds via Delta(1)-piperideine-2-carboxylate, l
      pipecolate, and Delta(1)-piperideine-6-carboxylate (alpha-aminoadipic
      semialdehyde). The two pathways are independent in the sense that certain
      mutants, unable to grow on l-lysine, grow at wild-type rates of d-lysine,
      utilizing the same intermediates as the wild type, as inferred from labeling
      studies. This finding implies that lysine racemase in our strain, while
      detectable in cell extracts, is not physiologically functional in intact cells at
      a rate that would permit growth of mutants blocked in the l-lysine pathway.
      Pipecolate oxidase, a d-lysine-related enzyme, is induced by d-lysine and less
      efficiently by l-lysine. Aminooxyacetate virtually abolishes the inducing
      activity of l-lysine for this enzyme, suggesting that lysine racemase, although
      functionally inactive for growth purposes, may still have regulatory significance
      in permitting cross-induction of d-lysine-related enzymes by l-lysine, and vice
      versa. This finding suggests a mechanism in bacteria for maintaining regulatory
      patterns in pathways that may have lost their capacity to support growth. In
      addition, enzymatic studies are reported which implicate Delta(1)-piperideine-2
      carboxylate reductase as an early step in the d-lysine pathway.

PMID- 4359656
TI  - Metabolism of D-arabinose by Escherichia coli B-r.
AB  - The pathway for d-arabinose metabolism in Escherichia coli B/r has been
      determined. Evidence is presented to support the following metabolic scheme: d
      arabinose d-ribulose right harpoon-up d-ribulose-5-phosphate d-xylulose-5
      phosphate.

PMID- 4359657
TI  - Further studies on the behavioural and biochemical interaction between caffeine
      and L-DOPA.

PMID- 4359658
TI  - Antagonism by DL-threo-DOPS of the suppression of a conditioned avoidance
      response induced by a dopamine-beta-hydroxylase inhibitor.

PMID- 4359659
TI  - [Comparative biochemical characteristics of the myocardium in resection and
      alloplasty of the cardiac wall (experimental study)].

PMID- 4359660
TI  - [Clinical and pathogenetic aspects of arterial hypertension in patients with
      kidney neoplasms].

PMID- 4359661
TI  - [Drugs which influence plasma fatty acids and lipoproteins. Opinion of Prof.
      Rodolfo Paoletti].

PMID- 4359662
TI  - The effects of perlapine on sleep.

PMID- 4359663
TI  - [Atypical mitochondria in the neurons of the turtle nucleus rotundus].

PMID- 4359664
TI  - [Problems in the diagnosis and treatment of synovialoma in the hand].

PMID- 4359665
TI  - [Physiopathology and diagnosis of renal hypertonus].

PMID- 4359666
TI  - [Indices of the functional state of the hypothalamo-hypophyseo-adrenal system in
      children suffering the neuro-endocrine form of the hypothalamic syndrome].

PMID- 4359667
TI  - Metal complex formation and its importance for enzyme regulation.

PMID- 4359668
TI  - Development of cell lines after exposure of chicken embryonic fibroblasts to
      herpes simplex virus type 2 at supraoptimal temperature.

PMID- 4359669
TI  - Herpes simplex virus latency in SV40 hamster tumour cells.

PMID- 4359670
TI  - Inhibition of virus multiplication by partially hydrolysed RNA: a possible
      membrane-effect.

PMID- 4359671
TI  - Measurement of personal exposure to 1,1,1-trichloroethane and trichloroethylene
      using an inexpensive sampling device and battery-operated pump.

PMID- 4359672
TI  - Standard quartz dq12 greater than 5 micro m for experimental pneumoconiosis
      research projects in the Federal Republic of Germany.

PMID- 4359673
TI  - Scleroma affecting the middle ear cavity with report of three cases.

PMID- 4359674
TI  - Anti-Epstein Barr virus antibody in nasopharyngeal carcinoma.

PMID- 4359675
TI  - Glomus jugulare tumors. II. A clinicopathologic analysis of the effects of
      radiotherapy.

PMID- 4359676
TI  - Tyrosine crystals in pleomorphic adenomas of the salivary gland.

PMID- 4359677
TI  - Letter: Congenital mesoblastic nephroma.

PMID- 4359678
TI  - Virus excretion in smallpox. 1. Excretion in the throat, urine, and conjunctiva
      of patients.
AB  - Excretion of virus in the throat, urine, and conjunctiva of smallpox patients was
      studied daily for 2-3 weeks after the onset of fever. The virus titre in the
      throat and urine of haemorrhagic and confluent cases was higher than in discrete
      cases. The duration of virus excretion was also greater in confluent cases than
      in discrete cases. Conjunctival swabs from all 12 smallpox patients with
      conjunctivitis were positive for virus. The duration and titre of virus excretion
      in the throat, urine, and conjunctiva of patients were not related to their age
      or sex and did not depend on whether or not they had received a primary
      vaccination.

PMID- 4359679
TI  - Virus excretion in smallpox. 2. Excretion in the throats of household contacts.
AB  - Throat swabs of 34 of 328 family contacts of 52 smallpox cases, examined 4-8 days
      after the onset of the disease in the family, were positive for variola virus.
      The log titre of virus per swab ranged from 2 to 3.95. A higher proportion of
      unvaccinated than of vaccinated contacts excreted the virus. Only 4 of the virus
      positive contacts developed clinical smallpox; this occurred 5-7 days after their
      swabs were examined. Excretion of virus in the throats of these contacts, a few
      of whom were in the incubation period of the disease, suggests the possibility
      that they could have spread the infection. This possibility, if kept in mind, may
      help in tracing the source of infection or in determining the incubation period
      in a few instances when difficulty is experienced.

PMID- 4359680
TI  - Evaluation of virological laboratory methods for smallpox diagnosis.
AB  - Between July 1966 and May 1972 the Vesicular Disease Laboratory, Center for
      Disease Control, Atlanta, Ga., USA, tested specimens from 849 suspected smallpox
      cases by at least 2 methods, electron microscopy and chick embryo chorioallantoic
      membrane (CAM) cultures. A smaller number of specimens was tested by each of 4
      methods: electron microscopy, CAM culture, agar gel precipitation, and tissue
      culture. For specimens handled in the field the CAM culture method was less
      sensitive than electron microscopy because the adverse conditions often
      inactivated the virus. CAM cultures were valuable for identifying members of the
      poxvirus subgroups, however, particularly when supplemented by tissue culture.
      The agar gel precipitation test was the least sensitive but was of value in
      confirming the results of electron microscopy. The latter was highly effective
      for the diagnosis of varicella, but dependably identified only about half of the
      vaccinia infections; for vaccinia, the CAM technique was essential. The
      occurrence of human monkeypox cases in West Africa emphasized that the usual
      smallpox diagnostic methods were inadequate. More sophisticated tests, such as
      the rabbit dermal sensitivity test, are necessary for accurate diagnosis of these
      cases as monkeypox.

PMID- 4359681
TI  - Characterization of poliovirus isolates in Japan after the mass vaccination with
      live oral poliomyelitis vaccine (Sabin).
AB  - From 1962 to 1968, 127 poliovirus isolates (92 from clinical specimens and 35
      from healthy subjects) were subjected to intratypic serodifferentiation by the
      modified Wecker and McBride techniques. The two techniques gave concordant
      results for 103 strains, 91 of which were classified as vaccine-like, 9 as
      nonvaccine-like, and 3 as intermediate; 20 were classified as vaccine-like by one
      technique and as intermediate by the other, and 4 as nonvaccine-like by one
      technique and as intermediate by the other. The origin of the nonvaccine-like
      strains is unknown, but it is unlikely that they had been circulating in the
      community long. An rct/40-marker test of the isolates revealed a higher
      positivity rate than that found in field trials of Sabin vaccine. The results
      indicate that wild poliovirus has been almost completely eradicated from Japan.

PMID- 4359682
TI  - Metabolite synthesis by rat liver cells and rat liver mitochondria.

PMID- 4359683
TI  - [Histones as genetic regulators].

PMID- 4359684
TI  - Effects of insulin, glucagon and adrenocorticotrophin on the levels of
      corticosteroids, noradrenaline, adrenaline and ascorbic acid in the adrenal
      glands of cats.

PMID- 4359685
TI  - The cyclic AMP content and karyotype of the somatic hybrids of mouse malignant
      and nonmalignant cells segregating in vivo and in vitro.

PMID- 4359686
TI  - A study of the relationship of virus-like particles and Australia antigen in
      liver.

PMID- 4359687
TI  - Cystosarcoma phyllodes--a study of 13 cases.

PMID- 4359688
TI  - Alpha fetoprotein levels in women taking oral contraceptives.

PMID- 4359689
TI  - Use of cyclofenil (Sexovid) to induce ovulation.

PMID- 4359690
TI  - Evaluation of endometrial biopsy in the cycle of conception.

PMID- 4359691
TI  - Sub-clinical endometrial inflammation and T-mycoplasma: a possible cause of human
      reproductive failure.

PMID- 4359692
TI  - A modified in vitro spermatozoal penenetration test. I. Method.

PMID- 4359693
TI  - A modified in vitro spermatozoal penetration test. II. Application in fertility
      investigations.

PMID- 4359694
TI  - Clinical trial and laboratory investigation of a low-dose progestogen-only
      contraceptive--Exluton.

PMID- 4359695
TI  - Characteristics of infection by RSV. I. Non-requirement for the S phase of
      cellular DNA synthesis.

PMID- 4359696
TI  - Characteristics of infection by RSV. II. Dependence on cell events which can
      occur in the G2 phase and after mitosis.

PMID- 4359697
TI  - Studies on a heat-labile variola virus inhibitor in normal sera. I. Detection by
      the variola focus reduction assay and its general characteristics.

PMID- 4359698
TI  - Studies on a heat-labile variola virus inhibitor in normal sera. II. Further
      characterization of the inhibitor and its activity.

PMID- 4359699
TI  - The protein neurotoxins in scorpion and elapid snake venoms.

PMID- 4359700
TI  - Factors associated with deterioration of kidney function in patients with spinal
      cord injury.

PMID- 4359701
TI  - Migraines in childhood.

PMID- 4359702
TI  - Chondroma of the tibia.

PMID- 4359703
TI  - Renal blood flow in the dog. Autoregulation and intrarenal distribution.

PMID- 4359704
TI  - Hyperlipidemia in experimental disseminated intravascular coagulation.

PMID- 4359705
TI  - [Entamoeba histolytica infection].

PMID- 4359706
TI  - [Acute hemoperitoneum due to asymptomatic Wilms' tumor].

PMID- 4359707
TI  - [Serum total and ionized calcium and calcium in the sweat during treatment of
      dietary deficiency rickets with vitamin D-3].

PMID- 4359708
TI  - [Virological studies of enteroviruses and adenoviruses in children in a creche in
      Warsaw].

PMID- 4359709
TI  - Inhibition of glycolytic metabolism and sleep-waking states in cats.

PMID- 4359710
TI  - Drinking in the monkey evoked by nicotine or angiotensin II microinjected in
      hypothalamic and mesencephalic sites.

PMID- 4359711
TI  - Sleep-waking patterns in cats after administration of fenfluramine and other
      monoaminergic modulating drugs.

PMID- 4359712
TI  - Formation of choline from phospholipid precursors: a comparison of the enzymes
      involved in phospholipid catabolism in the brain of the rhesus monkey.

PMID- 4359713
TI  - Studies on sedimentation characteristics of heterogeneous nuclear RNA.

PMID- 4359714
TI  - Spin echo nuclear magnetic resonance in cancerous tissue.

PMID- 4359715
TI  - Pharmacoangiography with angiotensin.

PMID- 4359716
TI  - Intra-arterial hepatography: experimental evaluation of a new contrast agent.

PMID- 4359717
TI  - [Hepatomas. Retrospective study].

PMID- 4359718
TI  - Poliovirus type 3 isolation from infants with respiratory diseases.

PMID- 4359719
TI  - [Effect of malathion on some reactions of respiratory enzymes and the
      ultrastructure of mitochondria in rat liver].

PMID- 4359720
TI  - A clinical approach to pain.

PMID- 4359721
TI  - Cell-mediated antitumor immune reactions under syngeneic conditions.

PMID- 4359722
TI  - Mixed leukocyte culture reactions with man-mouse hybrid cells.

PMID- 4359724
TI  - Correlation of MLC reactivity after experimental and clinical transplantation.
      Virus and cytophilic antibody: sources of false negatives.

PMID- 4359725
TI  - [Experience with dispensary treatment of workers with peripheral nervous system
      diseases].

PMID- 4359723
TI  - Virus plaque assay and enumeration of effector cells in mixed lymphocyte
      cultures.

PMID- 4359726
TI  - Sensitivity of Azotobacter chroococcum to some antibiotics.

PMID- 4359727
TI  - [Dysembryonal mixed tumor of the nasopharynx in a 7-year-old child].

PMID- 4359728
TI  - Reactive granular cells in sites of trauma. A cytochemical and ultrastructural
      study.

PMID- 4359729
TI  - Increased production of cyclic AMP in mechanically stressed alveolar bone in
      cats.

PMID- 4359730
TI  - Electron microscopic and chemical studies of the vascular changes and edema of
      lead encephalopathy. A comparative study of the human and experimental disease.
AB  - Lead encephalopathy was induced in suckling rats by administering lead to the
      mother. The brains were studied by light and electron microscopy, and the results
      were compared with observations in the human disease as well as in cases of
      cerebral ischemia in children. In their severe forms, both human and experimental
      lead encephalopathies are characterized by exudative extracellular edema and
      perivascular PAS-positive globules. The latter consist of osmiophilic non
      membrane-limited cytoplasmic inclusions located, in the rat exclusively and in
      the human predominantly, in perivascular astrocytes. Intervascular strands are
      also found in both forms of the disease. In the rat these consist of basement
      membrane surrounding endothelial cytoplasm. Chemically, experimental lead
      encephalopathy with morphologically demonstrable edema is associated with an
      increase in brain water, sodium and serum albumin. Relative to the serum
      concentration, the increase in water is disproportionately greater than the
      sodium or albumin. There were no demonstrable changes in chloride or potassium.

PMID- 4359732
TI  - Formation of multinucleate giant cells in organized epitheloid cell granulomas.
AB  - Organized epithelioid cell granulomas were produced experimentally by injecting
      intradermally dilute suspensions of zirconium and beryllium salts into
      individuals who had been previously sensitized to these metals. Biopsies were
      obtained at intervals of between 5 days and 13 months later, and the specimens
      were fixed and prepared for light and electron microscopy. Tritiated thymidine
      was injected into a number of the granulomas; the biopsy specimens were secured
      from 40 minutes to 2 or more weeks later, and the tissues were processed for
      light microscopic autoradiography. Giant cells occurred commonly, both within
      organized tubercles and in relation to areas of necrosis, and had markedly
      different cytoplasmic features from typical secretory epithelioid cells which
      enabled them to be readily recognized at scanning magnifications. The
      characteristic hallmark of these giant cells was the presence of myriads of small
      mitochondria adjacent to nuclei with numerous membrane-lined vesicles in the
      center of the cell. Giant cells occurred mainly in edematous disrupted tubercles.
      In these tubercles, epithelioid cells contained cytoplasmic components more like
      giant cells. Direct evidence of cell fusion was not seen, although fusion of
      membranes seemed to occur between cells having similar cytoplasmic features. The
      failure to find labeled nuclei in any giant cells 40 minutes after injection of
      tritiated thymidine indicates that normal nuclear division does not occur within
      giant cells. We postulate that epithelioid cells containing vesicles develop in
      damaged and necrotic areas, and that mainly this type of epithelioid cell fuses
      to form giant cells.

PMID- 4359731
TI  - Mitochondrial conformation and swelling-contraction reactivity during early liver
      regeneration.
AB  - Studies of mitochondrial respiratory control and swelling contraction activity
      during early cell regeneration after partial hepatectomy have revealed a
      selective defect in the rate of substrate-supported, phosphate-induced
      mitochondrial swelling. Swelling profiles induced by Fe(2-) or Cu(2-) revealed no
      differences between sham-operated and partially hepatectomized mice, which
      suggests no defects in -SH group composition or ability to form lipid peroxides.
      The specific activity of mitochondrial cytochrome c oxidase was unchanged. There
      was no significant mitochondrial swelling in situ as determined from mitocrit and
      mitochondrial protein ratios. A significant decline in respiratory control and
      efficiency of oxidative phosphorylation was found in mitochondria from animals 8
      and 24 hours after partial hepatectomy, partially reversed by bovine serum
      albumin. No significant change in ADP:O ratio was noted and the decrease in RCI
      was due primarily to a significant decline in state 3 respiration rate. In situ
      electron microscopic studies of mitochondria failed to reveal significant
      abnormalities during early cell regeneration apart from decrease in numbers of
      matrix granules, focal matrix rarefaction and predominance of round forms.
      Electron microscopic studies of mitochondria after in vitro phosphate-induced
      swelling experiments showed no differences between sham and partially
      hepatectomized animals, but revealed two distinct populations of mitochondria,
      the predominant form (type III) showing distortion, matrix lucency and outer
      membrane rupture. ATP induced a diminished reversal in light scattering in
      partially hepatectomized mitochondria even when examined at 20 minutes,
      manifested as an increase in numbers of orthodox mitochondrial forms at the
      expense of the swollen type III forms. The pathogenesis of the impaired
      respiratory control and phosphate-induced swelling is unknown, but analogous
      observations have been found in mitochondria harvested from cells in which
      abnormal accumulations of free fatty acids have been demonstrated.

PMID- 4359733
TI  - Separation of cells having histochemically demonstrable glucose-6-phosphatase
      from suspensions of hamster kidney cells in an isokinetic density gradient of
      Ficoll in tissue culture medium.
AB  - Suspensions of enzymatically disaggregated hamster kidney cells were separated
      primarily according to differences in diameter using velocity sedimentation in a
      previously described isokinetic density gradient and according to differences in
      density in an isopycnic density gradient. Cells which contained histochemically
      demonstrable glucose-6-phosphatase were thought to be cells from proximal tubules
      and constituted 46.5 +/- 14.1% of the cells in the starting sample suspension of
      disaggregated kidney cells. The purest gradient fractions from experiments using
      velocity sedimentation contained 98.0 +/- 0.6% cells which demonstrated glucose-6
      phosphatase activity. More than 99.0% of these cells excluded trypan blue.
      Isopycnic sedimentation was not an effective means of purifying proximal tubule
      cells.

PMID- 4359734
TI  - Lesions of the islets of Langerhans in encephalomyocarditis virus-infected mice
      with diabetes mellitus-like disease. I. Acute lesions.
AB  - Mice infected with the M variant of the encephalomyocarditis (EMC) virus develop
      lesions of the islets of Langerhans associated with a diabetes mellitus-like
      disease. Ultrastructural alterations become evident in capillaries and beta cells
      at a time when large amounts of virus are present in the pancreatic tissue.
      Although some beta cells become necrotic, degranulation and contraction of intact
      cells is the prominent lesion. Changes in the capillaries appear early in the
      course of the infection and later are associated with interstitial fibrosis in
      and around the islets. During early convalescence, beta cells are degranulated
      and exhibit striking alterations of cytoplasmic organelles. These changes appear
      to be consequent to increased metabolic activity by the residual insular tissue.
      Interestingly enough, specific lesions of the alpha cells are not observed.

PMID- 4359735
TI  - Histopathology of early myocardial infarcts. A new approach.
AB  - The histopathology of human myocardial infarcts is reviewed in a series of 46
      cases ranging from sudden death to a clinical age of 3 days. A set of
      histopathologic features is described whereby the diagnosis of acute myocardial
      infarction can be made, even in cases of sudden death, on routine sections and
      even after considerable autolysis. This is primarily a stretching and waviness of
      the myocardial fibers, especially at the border of the infarcted area. Its
      mechanism is probably twofold: the rythmical pull exerted by the normal
      myocardium against the infarcted paralyzed area and the outward bulging of this
      area at every systole. On the basis of human material alone, it may be inferred
      that this pattern develops very rapidly: surely less than 1 hour and perhaps a
      few minutes after the local circulation has failed.

PMID- 4359736
TI  - Clinical evaluation of live, oral types 1, 2, and 5 adenovirus vaccines.

PMID- 4359737
TI  - Moderate ethanol ingestion and plasma triglyceride levels. A study in normal and
      hypertriglyceridemic persons.

PMID- 4359738
TI  - Airways function during mild viral respiratory illnesses. The effect of
      rhinovirus infection in cigarette smokers.

PMID- 4359739
TI  - 1,25 Dihydroxy-vitamin D3 in normal man and patients with renal failure.

PMID- 4359740
TI  - Hypercalcemia in bronchogenic carcinoma. A prospective study of 200 patients.

PMID- 4359741
TI  - Letter: Hypercalcemia and streptozotocin.

PMID- 4359742
TI  - Letter: Hypercalcemia and streptozotocin. In comment.

PMID- 4359743
TI  - Sequential enzymolysis of ligament and resultant stress-strain behavior.

PMID- 4359744
TI  - Electron spinal resonance analysis of the nitroxide spin label 2,2,6,6
      tetramethylpipidone-N-oxyl (Tempone) in single crystals of the reduced Tempone
      matrix.
AB  - The nitroxide spin label Tempone (2,2,6,6-tetramethylpiperidone-N-oxyl) can be
      reduced with ascorbic acid to give a nonparamagnetic species. Single crystals of
      reduced Tempone serve as a suitable host matrix to orient trace quantities of
      Tempone for ESR analysis. In these crystals the majority of the Tempone molecules
      are well-oriented, but a smaller fraction of the molecules tumble freely to give
      an isotropic electron spin resonance (ESR) spectrum. ESR transitions for the
      oriented molecules are saturated at much lower microwave power levels than for
      the tumbling molecules. For the oriented molecules, an analysis of the anisotropy
      of the spectroscopic splitting factor (g) gives principal values of g(1) =
      2.0094, g(2) = 2.0061, g(3) = 2.0021. The hyperfine coupling tensor is nearly
      axially symmetric, with principal values (in gauss) of A(1) = 6.5, A(2) = 6.7,
      A(3) = 33.0. Within experimental error, the principal axis systems for the g
      tensor and the hyperfine tensor are identical. Comparison of the average values
      of g and A with the isotropic values of these parameters for Tempone in solvents
      of different polarity suggests a method for choosing the most appropriate tensor
      elements to be used for spin label experiments in various solvent systems.

PMID- 4359745
TI  - Electrochemical properties of hydrated cation-selective glass membrane. A model
      of K+ and Na+ transport.
AB  - Electrochemical properties of cation-selective glass microelectrodes made from
      NAS(27-04) were studied. There was a marked fall in electrical resistance of the
      microelectrodes stored in 3 M KCl solution (aging). The resistance was in the
      range of 2 x 10(7) to 10(9) Omega, which were much lower than those estimated
      from the electrical resistivity of dry glass for the equivalent dimensions of
      microelectrode working tips. This fall in resistance was accompanied by an
      increase in microelectrode selectivity for K(+). The low resistance and increased
      K(+) selectivity are desirable features that make the microelectrode more
      suitable for application to biologic studies. The changes in microelectrode
      resistance and selectivity were interpreted to be due to hydration of the entire
      thickness of the glass membrane, resulting in a change in the field strength of
      anionic sites and formation of ionic channels in the glass membrane. Thus, the
      fall in resistance is explained by decrease in energy barrier, which is
      equivalent to the activation energy of interaction between the cations and
      anionic sites in the glass membrane. Some of the microelectrodes showed a
      transient depolarization that resembled the action potential of a biological
      membrane. This transient depolarization was associated with the changes in
      microelectrode resistance and selectivity. The transient depolarizations suggest
      the temporary development of wide channels in the membrane permitting free
      movement of hydrated cations according to the bulk electrochemical gradient.

PMID- 4359746
TI  - Plasma testosterone: an accurate monitor of hormone treatment in prostatic
      cancer.

PMID- 4359747
TI  - Letter: Type IV hyperlipidaemia in cord blood.

PMID- 4359748
TI  - The effect of diphenylhydantoin on insulin response.

PMID- 4359749
TI  - Affinity of calciferol analogues for 25-hydroxycholecalciferol receptors.

PMID- 4359750
TI  - Effects of angiotensin on plasma electrolyte concentrations in rabbits and in
      man.

PMID- 4359751
TI  - Proceedings: Pressor sensitivity to angiotensin II in relation to sodium.

PMID- 4359752
TI  - The effect of modifying the combination of insulin with rat adipose cells on the
      intracellular levels of cyclic AMP.

PMID- 4359753
TI  - The effect of a distant reparative process on rat liver function.

PMID- 4359754
TI  - Effects of sodium, angiotensin, and steroids on vascular reactivity in man.

PMID- 4359755
TI  - Derivation of TK- clones from revertant TK+ mammalian cells.
AB  - In order to obtain a large collection of Chinese hamster cell clones defective in
      thymidine kinase (TK(-)), BrdU(r) selection experiments have been performed on
      wild-type and revertant TK(+) cell lines. No clones (< 10(-9)) were obtained from
      the wild-type TK(+) cell line by single-step selection. In contrast, revertant
      TK(+) clones readily gave rise to stable TK(-) derivatives (1 - 2 x 10(-4)). Both
      wild-type and revertant TK(+) clones spontaneously yielded 8-AG(r) colonies with
      the same frequency (1 - 5 x 10(-6)), suggesting that the differences between wild
      type and revertant cell lines specifically affected selection of the TK(-)
      phenotype. The increased frequency of TK(-) clones reflects perhaps the number
      (ploidy) or character of the autosomal TK loci in TK(+) revertants, or perhaps
      the mechanisms which regulate expression of the TK genes. Several mutagens, EMS,
      MNNG and UV, stimulated the TK(+) revertants' frequency of TK(-) subclones only
      slightly (< 3-fold). Biochemical and genetic data indicated that the TK(-) clones
      derived from one revertant are phenotypically different. The phenotypes displayed
      by these cell lines are stable and do not depend upon the continued presence of
      the selective agent.

PMID- 4359757
TI  - Defective virions of herpes simplex viruses.

PMID- 4359756
TI  - Low gene variation in Drosophila busckii.
AB  - Study of allozyme variation in D. busckii at thirty loci gives the proportion of
      polymorphic loci =.166 and the proportion of loci heterozygous per individual
      =.044. D. busckii has a narrower seasonal and food niche than the other domestic
      species D. melanogaster which has more allozyme variation. It is suggested that
      the low gene variation in D. busckii might be due to adaptation of this species
      to a narrow niche.

PMID- 4359758
TI  - Resistance of hamster cells transformed by herpes simplex virus type 2 to
      superinfection by herpes simplex viruses.

PMID- 4359759
TI  - In vitro transcriptase activity of vesicular stomatitis virus B and T particles:
      analysis of product.

PMID- 4359760
TI  - Control of gene expression in rat cells transformed by a cold-sensitive murine
      sarcoma virus (MSV) mutant.

PMID- 4359761
TI  - Biochemical and biophysical characterization of calicivirus isolates from
      pinnipeds.

PMID- 4359762
TI  - Agglutinability of Rous cells by concanavalin A: study with a temperature
      sensitive RSV mutant and inhibitors of macromolecular synthesis.

PMID- 4359763
TI  - Differential phosphorylation and turnover of nuclear acidic proteins during the
      cell cycle of synchronized HeLa cells.

PMID- 4359764
TI  - Binding of adenosine diphosphate by isolated membranes from human platelets.

PMID- 4359765
TI  - Fish liver fructose 1,6-diphosphatase. 3. The effect of temperature on the
      regulatory properties of the carp (Cyprinus carpio) liver enzyme.

PMID- 4359766
TI  - Nuclear protein kinases. Evidence for their heterogeneity, tissue specificity,
      substrate specificities, and differential responses to cyclic adenosine 3':5'
      monophosphate.

PMID- 4359767
TI  - Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in
      cultured human fibroblasts. Comparison of cells from a normal subject and from a
      patient with homozygous familial hypercholesterolemia.

PMID- 4359768
TI  - Near ultraviolet circular dichroism and absorption spectra of chicken ovomucoid
      and acetylated derivatives at 297 and 77 degrees K.

PMID- 4359769
TI  - Properties of angiotensin II receptors in the bovine and rat adrenal cortex.

PMID- 4359770
TI  - Nuclear deoxyribonucleic acid polymerase. Purification and properties of the
      homogeneous enzyme from human KB cells.

PMID- 4359771
TI  - Induction of delta-aminolevulinic acid synthetase in isolated rat liver cell
      suspensions. Adenosine 3':5'-monophosphate dependence of induction by drugs.

PMID- 4359772
TI  - Induced reoxidation and reactivation of a reduced uridine diphosphate galactose-4
      epimerase complex.

PMID- 4359773
TI  - Molecular basis of the biological function of molybdenum. Effect of tungsten on
      xanthine oxidase and sulfite oxidase in the rat.

PMID- 4359774
TI  - The metabolism of cyclopropane fatty acids by Tetrahymena pyriformis.

PMID- 4359776
TI  - Structural analyses of mammalian ribosomal ribonucleic acid and its precursors.
      The distribution of polypyrimidine sequences in ribosomal 28 S ribonucleic acid.

PMID- 4359775
TI  - Evidence for randon distribution and translational movement of cytochrome b5 in
      endoplasmic reticulum.

PMID- 4359777
TI  - Anomeric specificity of the alkaline form of fructose 1,6-diphosphatase from
      rabbit liver.

PMID- 4359778
TI  - Multiple forms of flounder muscle glyceraldehyde 3-phosphate dehydrogenase.
      Subunit composition, properties, and tissue distribution of the forms.

PMID- 4359779
TI  - Communication: Coacervation of tropoelastin results in fiber formation.

PMID- 4359780
TI  - Induction of cellular immunity to herpes simplex virus: relationship to the
      humoral immune response.

PMID- 4359781
TI  - Host response to tumor-associated fetal antigens.

PMID- 4359782
TI  - In vitro immune stimulation-inhibition to spontaneous canine tumors of various
      histologic types.

PMID- 4359783
TI  - In vitro study of antiviral activity of immune spleen cells in experimental
      Venezuelan equine encephalomyelitis infection in mice.

PMID- 4359784
TI  - The production of interferon by malignant plasma cells from patients with
      multiple myeloma.

PMID- 4359785
TI  - Acid lability of rhinoviruses: loss of C and D antigenicity after treatment at pH
      3.0.

PMID- 4359786
TI  - Immunochemical quantitation of cell bound C4.

PMID- 4359788
TI  - A basis for extracellular current density analysis in cerebellar cortex.

PMID- 4359787
TI  - In vivo suppression by cholera toxin of cell-mediated and foreign body
      inflammatory responses.

PMID- 4359789
TI  - Organization of vestibular nystagmus in oblique oculomotor system.

PMID- 4359790
TI  - Observations on phase-sensitive neurons of anteroventral cochlear nucleus of the
      cat: nonlinearity of cochlear output.

PMID- 4359791
TI  - Identification of unitary potentials in turtle cerebellum and correlations with
      structures in granular layer.

PMID- 4359792
TI  - Response characteristics of single units in the rat's trigeminal nuclei to
      vibrissa displacements.

PMID- 4359793
TI  - Hepatic ultrastructural changes in murine lupinosis.

PMID- 4359794
TI  - Ultrastructure of the alveolar-capillary wall in mitral stenosis.

PMID- 4359795
TI  - Cell death in the normal neonatal rat adrenal cortex.

PMID- 4359796
TI  - Studies on the pathogenesis of corneal arcus formation. I. The human corneal
      arcus and its relation to atherosclerosis as studied by immunofluorescence.

PMID- 4359797
TI  - An ultrastructural study of the effect of ultrasound on arterial tissue.

PMID- 4359798
TI  - Poliovirus antibody in urban school children.

PMID- 4359799
TI  - Antibody titers to polioviruses in patients ten years after immunization with
      sabin vaccine.

PMID- 4359800
TI  - Wilms' tumor metastasis to uncommon sites.

PMID- 4359801
TI  - [Activity of renin in blood plasma of patients with arterial hypertension].

PMID- 4359802
TI  - [Laboratory tests and virus diseases].

PMID- 4359803
TI  - Fever and petechiae with adenovirus type 7 infection.

PMID- 4359804
TI  - 6-OHDA lesions of the hypothalamus: interaction of aphagia, food palatability,
      set-point for weight regulation, and recovery of feeding.

PMID- 4359805
TI  - Drinking elicited by intracranial microinjection of angiotensin in the cat.

PMID- 4359806
TI  - Lever-pressing behavior caused by intraseptal angiotensin II in water satiated
      rats.

PMID- 4359807
TI  - Taming effect of nonnarcotic analgesics on the septal syndrome in rats.

PMID- 4359808
TI  - Responsiveness to flickering light in waking and sleeping infants.

PMID- 4359809
TI  - A micromethod for the measurement of human plasma renin activity.

PMID- 4359810
TI  - Plasma renin activity in the newly born and in young infants.

PMID- 4359811
TI  - N-acetyl-2-O-methyl-tyrosine-oxytocin: a specific antagonist of oxytocin.

PMID- 4359812
TI  - Treatment of chondritis in the burned ear by the local instillation of
      antibiotics.

PMID- 4359813
TI  - Congenital epulis tumor. Case report.

PMID- 4359814
TI  - Persistence of abnormal REM sleep response to ethanol as a result of previous
      ethanol ingestion.

PMID- 4359815
TI  - Persistence of cadmium-induced metabolic changes in liver and kidney.
AB  - Daily intraperitoneal injection of cadmium chloride (1 milligram per kilogram)
      for 45 days enhanced gluconeogenesis as evidenced by significant increases in the
      activities of liver and kidney cortex pyruvate carboxylase, phosphopyruvate
      carboxylase, hexosediphosphatase, and glucose-6-phosphatase, the quartet of key,
      rate-limiting enzymes involved in the biotransformation of noncarbohydrate
      precursors into glucose. Whereas cadmium treatment decreased the level of hepatic
      glycogen, the concentration of blood glucose and urea was significantly elevated
      by this heavy metal. Discontinuation of the heavy metal treatment for 28 days, in
      rats previously injected with cadmium for 45 days, failed to restore the observed
      biochemical alterations in hepatic and renal carbohydrate metabolism to control
      values. Evidence indicates that cadmium augments the glucose-synthesizing
      capacity of liver and kidney cortex and that various metabolic changes persist
      even after a 4-week period of withdrawal from exposure to the heavy metal.

PMID- 4359816
TI  - Intravenous infusion of hydrochloric acid for treatment of severe metabolic
      alkalosis.

PMID- 4359817
TI  - Cold lymphocytotoxins in infections and parasitic infestations.

PMID- 4359818
TI  - Complement-fixing antibodies to the AD-169 strain of cytomegalovirus in banked
      blood.

PMID- 4359819
TI  - [Segmental disorders in amyotrophic lateral sclerosis (according to a study of
      reflex and antidromal excitability of alpha-motor neurons)].

PMID- 4359820
TI  - [Clinical, electroencephalographic and pneumoencephalographic studies in the
      dementive-paretic form of Viliuisk encephalitis (encephalomyelitis)].

PMID- 4359821
TI  - [Ultrastructure of the Golgi tendon organ in the cat].

PMID- 4359822
TI  - [Comparative studies on physico-chemical methods of assaying vitamin D. II.
      Assays of vitamin D in crystalline preparations and preparations of same
      following chromatographic separation from accompanying substances].

PMID- 4359823
TI  - Bacterial pneumonia complicating adenoviral pneumonia. A comparison of
      respiratory tract bacterial culture sources and effectiveness of chemoprophylaxis
      against bacterial pneumonia.

PMID- 4359824
TI  - Diagnostic and surgical aspects of insulinoma. A review of twenty-seven cases.

PMID- 4359825
TI  - Studies on clonazepam, flunitrazepam, and related benzodiazepines in cat and
      monkey.

PMID- 4359826
TI  - Effect of prostaglandin F2alpha on responses on vascular smooth muscle to
      serotonin, angiotensin and epinephrine.

PMID- 4359827
TI  - Subcutaneous mastectomy and immediate prosthetic implantation as an alternative
      to simple mastectomy.

PMID- 4359828
TI  - [Biologically effective organo-silicious compounds--advances, problems,
      prospects].

PMID- 4359829
TI  - Fibrinous pseudointimas within impermeable silastic-nylon velour. I.
      Ultrastructure of cell components at initial stages and cell population changes
      in the earlier pseudointima.

PMID- 4359830
TI  - [Epstein-Barr virus antibody pattern in lymphoproliferative disorders in children
      and young adults].

PMID- 4359831
TI  - Registers and registries: a review.

PMID- 4359832
TI  - Immunization during pregnancy against poliomyelitis and influenza in relation to
      childhood malignancy.

PMID- 4359833
TI  - Peculiar lipid inclusions in the hepatic parenchymal cell of a patient with
      hereditary spherocytosis.

PMID- 4359834
TI  - Stimulation of phagocytic release of neutral protease from human neutrophils by
      cholinergic amines and cyclic 3',5'-guanosine monophosphate.

PMID- 4359835
TI  - Letter: Prevention of postsurgical ulnar neuropathy.

PMID- 4359836
TI  - Homozygous type II hyperlipoproteinemia treatment. Partial ileal bypass in two
      children.

PMID- 4359837
TI  - Ear piercing and hepatitis. Nonsterile instruments for ear piercing and the
      subsequent onset of viral hepatitis.

PMID- 4359838
TI  - [11-OCS level and the binding ability of transcortin in patients with congestive
      circulatory insufficiency].

PMID- 4359839
TI  - Ovarian tumors. Tumors and tumor-like conditions of the ovaries, fallopian tubes
      and ligaments of the uterus.

PMID- 4359840
TI  - [Energy metabolism in the skeletal and heart muscles after adrenalectomy].

PMID- 4359842
TI  - [Enzymatic methemoglobinemia].

PMID- 4359843
TI  - NIMH-sponsored chemical synthesis program.

PMID- 4359841
TI  - The baboon. Microbiology, clinical chemistry and some hematological aspects.

PMID- 4359844
TI  - [Treatment of bronchial carcinoma].

PMID- 4359845
TI  - [Skeletal changes, mistaken for primary bone neoplasms].

PMID- 4359846
TI  - [Contrasting of the lymph structures of the mediastinum].

PMID- 4359847
TI  - Mixed mesodermal tumors of the uterus.
AB  - Two of five women with mixed mesodermal tumor of the uterus are well more than
      ten years after therapy. A third was well when last seen two years after therapy
      and died at age 84 but autopsy was not done. Review of the literature and the
      reported experience indicates that this diagnosis should be suspected more often.
      Since histologic features may vary from one place to another within the lesion,
      accurate assessment requires examination of adequate specimens of the tumor. The
      mere presence of heterologous elements in an endometrial carcinoma changes the
      five-year survival rate from 85 percent to less than 35 percent. While total
      abdominal hysterectomy with bilateral salpingo-oophorectomy is mandatory,
      radiation therapy should be added more often than in the past, as it has been
      clearly shown that many of these tumors are radiosensitive.

PMID- 4359848
TI  - Forty-day fever. An epidemic of cytomegalovirus disease in a renal transplant
      population.
AB  - An epidemic of cytomegalovirus disease (CMV) occurred in 38 percent of 34 renal
      transplant recipients during an 18-month period. A characteristic clinical
      pattern was noted: 40 days following transplantation, daily fevers recurred for
      periods of four to six weeks. This fever in conjunction with a diffuse
      interstitial pneumonitis and impaired hepatic and renal function constituted a
      diagnostic tetrad. Of all the laboratory techniques, throat and urine cultures
      were the most consistent in confirming the diagnosis. Analysis of the epidemic
      implicated the communal hemodialysis unit as the source of exposure to the virus.
      CMV was not seen in the first 86 patients who received transplants in the
      program, but with increasing use of hemodialysis, the percentage of patients with
      positive serologic reaction for CMV increased dramatically.

PMID- 4359850
TI  - The ubiquitous adenovirus.

PMID- 4359849
TI  - Specialty conference: potpourri of adenoviral infections.

PMID- 4359852
TI  - Induced cellular autophagy in the epithelial cells of seminal vesicle of mice
      treated with actinomycin D.

PMID- 4359851
TI  - Effect of hyper- and hypothyreosis on cytochrome oxidase and succinic
      dehydrogenase activities of the rat kidney.

PMID- 4359853
TI  - Morphological aspects of protein synthesis.

PMID- 4359854
TI  - Control of protein synthesis in anterior pituitary gland.

PMID- 4359855
TI  - Oestrogen induced synthesis of a protein in avian liver.

PMID- 4359856
TI  - Protein synthesis in reproductive tissue. Transactions of the sixth symposium
      held in Geneva on May 21-23, 1973.

PMID- 4359858
TI  - Amebiasis presenting as an acute abdomen.

PMID- 4359859
TI  - Milk-rejection sign of breast cancer.

PMID- 4359857
TI  - Initiation of free radical reactions and hepatotoxicity in rats poisoned with
      carbon tetrachloride or bromotrichloromethane.

PMID- 4359860
TI  - Galactography in the examination of secretory breasts.

PMID- 4359861
TI  - [Participation of C 14-L-asparaginic acid in biosynthesis of polymyxin M].

PMID- 4359862
TI  - [Penicillin chromatography in sorbent thin layer. Quality control of 6
      aminopenicillanic acid].

PMID- 4359863
TI  - [Experimental study on the effect of fusidin on vaccine poxvirus].

PMID- 4359864
TI  - Effects of various mitogens on the phospholipid metabolism of human peripheral
      lymphocytes.

PMID- 4359865
TI  - On the metabolic conversion of human plasma very low density lipoprotein to low
      density lipoprotein.

PMID- 4359866
TI  - Metabolism of rat plasma very low density lipoprotein. I. Fate in circulation of
      the whole lipoprotein.

PMID- 4359867
TI  - Metabolism of rat plasma very low density lipoprotein. II. Fate in circulation of
      apoprotein subunits.

PMID- 4359868
TI  - Identification of lipoprotein families in familial lecithin: cholesterol
      acyltransferase deficiency.

PMID- 4359869
TI  - Comparative studies on adrenal iron-sulfur protein and its selenium derivatives
      by electron nuclear double resonance.

PMID- 4359870
TI  - The effect of K+ and pH on protein-dodecylsulphate complexes.

PMID- 4359871
TI  - The intracellular distribution of the radiocopper derived from ceruloplasmin and
      from albumin.

PMID- 4359872
TI  - Application of the fluorescent antibody technique to the diagnosis of avian
      encephalomyelitis.
AB  - A direct fluorescent antibody test was applied to the diagnosis of avian
      encephalomyeltis in experimental chicks and in chicks from three natural
      outbreaks of the disease. Intracerebrally inoculated chicks exhibited maximum
      fluorescence in brain tissue during the early clinical stages of the disease and
      similar observations were made on natural cases. Best fluorescence was obtained
      with frozen sections of cerebellum and pancreas from chicks approximately three
      weeks of age, but after four weeks of age it was not possible to diagnose the
      naturally-occurring (field) disease by this method. In these cases a diagnosis of
      avian encephalomyelitis was confirmed by the application of the fluorescent
      technique to the brains of either (a) chicks which had hatched from eggs
      inoculated with brain homogenates from the field cases or (b) hatched chicks
      which had been inoculated with the homogenates by the intracerebral route.

PMID- 4359874
TI  - Effects of dietary cholesterol on bile acid synthesis in liver and hepatomas.

PMID- 4359873
TI  - Experimental alkylmercurial poisoning in swine. Lesions in the peripheral and
      central nervous systems.
AB  - The effects of alkylmercurial poisoning were studied in 16 pigs poisoned with
      daily oral doses of a fungicide containing methylmercury 2, 3-dihydroxy propyl
      mercaptide and methylmercury acetate. Clinical signs included weakness, wobbling
      gait, blindness, recumbency and death. Microscopic studies of the peripheral
      nervous system revealed Wallerian degeneration in sensory fibers and neuronal
      degeneration in dorsal root ganglia. In the central nervous system, there were
      neuronal degeneration of ischemic type, glial degeneration, gliosis and necrosis
      of the media of meningeal arterioles. The last mentioned lesion was not
      extensive.The sequential development o lesions and the absence of segmental
      demyelination suggest that the primary lesion in the peripheral nervous system
      was neuronal-axonal degeneration rather than degeneration of the Schwann cell and
      myelin sheath.

PMID- 4359875
TI  - Spectrophotometric analysis of cytochromes in rat liver during carcinogenesis.

PMID- 4359877
TI  - Lack of syncytium formation by a type C virus-producing XC cell line in the mixed
      culture cytopathogenicity test.

PMID- 4359876
TI  - Inhibition of purine ribonucleotide and phosphoribosyl pyrophosphate synthesis by
      6-cyclopentylthio-9-hydroxymethylpurine and structurally related compounds.

PMID- 4359878
TI  - An electron microscopic study of spontaneous and experimentally induced leukemia
      in ICRC mice.

PMID- 4359879
TI  - Prevention of 334C murine virus-induced leukemia by transmission of maternal
      immunity to offspring.

PMID- 4359880
TI  - Inhibition of ribosomal RNA maturation in Novikoff hepatoma cells by toyocamycin,
      tubercidin, and 6-thioguanosine.

PMID- 4359881
TI  - Effect of aminonucleoside on serum stimulation of nonhistone nuclear protein and
      DNA synthesis in normal and SV40-transformed human fibroblats.

PMID- 4359882
TI  - Effect of a carcinogenic oral dose of 7, 12-dimethylbenz(a)anthracene on receptor
      binding of estradiol-17 beta in uterus and mammary tissue throughout lactation in
      the rat.

PMID- 4359883
TI  - Glucocorticoid receptors and mechanism of resistance in the cortisol-sensitive
      and -resistant lines of lymphosarcoma P1798.

PMID- 4359884
TI  - Imbalance in ornithine metabolism in hepatomas of different growth rates as
      expressed in behavior of L-ornithine:2-oxoacid aminotransferase (ornithine
      transaminase, EC 2.6.1.13).

PMID- 4359885
TI  - Identity of the paramagnetic element found in increased concentrations in plasma
      of cancer patients and its relationship to other pathological processes.

PMID- 4359886
TI  - Transfer RNA base composition studies in Morris hepatomas and rat liver.

PMID- 4359887
TI  - [Ultrastructure of clear cell carcinoma in the upper respiratory ways].

PMID- 4359888
TI  - On the pathological modification of serum high density lipoproteins in liver
      diseases. An alteration in the binding mode of indocyanine-green with human serum
      proteins.

PMID- 4359889
TI  - The inorganic pyrophosphatase activity associated with the forms of alkaline
      phosphatases isolated from human serum.

PMID- 4359890
TI  - Cyclic AMP stimulated phosphorylation of erythrocyte membranes from cystic
      fibrosis and control subjects.

PMID- 4359891
TI  - 5'nucleotidase: recent advances in cell biology, methodology and clinical
      significance.

PMID- 4359893
TI  - [Experimental substantiation of hygienic standardization of sodium
      hexametaphosphate and tripolyphosphate in drinking water].

PMID- 4359892
TI  - Screening for primary liver cancer. The relationship between the time of
      appearance of alpha-foetoprotein in the serum and clinical symptoms in nine
      cases.

PMID- 4359895
TI  - Glomus tumor. A case report.

PMID- 4359894
TI  - Computer extraction of an ultradian cycle in sleep from manually scored sleep
      stages.

PMID- 4359896
TI  - Bovine enteroviruses in the calf: an attempt at serologic, biologic, and
      pathologic classification.

PMID- 4359897
TI  - Preslaughter treatment affecting intramuscular and plasma lipids. I. Effect of
      ACTH in rabbits.

PMID- 4359898
TI  - The derivation of plasma-free fatty acids from dietary neutral fat in man.

PMID- 4359899
TI  - Leroy's l-cell disease: markedly increased activity of plasma acid hydrolases.

PMID- 4359900
TI  - Genetic manipulation of motor output in shaker mutants of Drosophila.

PMID- 4359901
TI  - Some physiological and biochemical features of striated muscles reinnervated by
      preganglionic sympathetic fibers.

PMID- 4359902
TI  - Identity of "dumbbell" profiles in synaptosomal fractions from rat brain.

PMID- 4359903
TI  - Future directions for automated analysis.

PMID- 4359904
TI  - [Determination of adrenocorticotropic hormone and 17-hydroxycorticosteroids in
      cancer of the corpus uteri, its recurrences and metastases].

PMID- 4359905
TI  - Changes in the excitability of Renshaw cells due to orthodromic tetanic stimuli.

PMID- 4359906
TI  - T-shaped cells of dorsal ganglia can influence the pattern of afferent discharge.

PMID- 4359907
TI  - RNA viruses: the age of innocence ends.

PMID- 4359909
TI  - [Primary herpetic gingivo-stomatitis in adults].

PMID- 4359908
TI  - Visna virus infection of American lambs.
AB  - Random-bred fetal and 4-week-old American lambs, inoculated intracerebrally with
      visna virus, developed a persistent infection in the brain and sometimes in the
      lung. The pathologic changes present in these lambs were similar to the early
      lesions of visna in Icelandic sheep, thus providing a possible model for the
      study of virus-induced demyelinating disease.

PMID- 4359910
TI  - Congenital infections due to reovirus type 3 in hamsters.

PMID- 4359912
TI  - [Present state and tasks in the scientific research in herpesvirus and adenovirus
      eye diseases].

PMID- 4359913
TI  - [Morphological changes in tissue culture cells exposed to L forms of S. typhi].

PMID- 4359911
TI  - Effect of furosemide administration and upright position on plasma renin activity
      and angiotensin II in hypertension.

PMID- 4359914
TI  - [Use of live poliomyelitis vaccine and circulation of enteroviruses in the
      Estonian SSR in 1965-1970].

PMID- 4359915
TI  - [Synaptic influences on corticorubral tract neurons in cats].

PMID- 4359916
TI  - [A double jubilee of the teaching of I. P. Pavlov concerning higher nervous
      activity].

PMID- 4359917
TI  - Primary linitis plastica of the rectum. Report of two cases.

PMID- 4359918
TI  - The structure of novel C35 pentacyclic terpenes from Acetobacter xylinum.
AB  - A novel C(35) terpene and its monounsaturated analogue were isolated from
      cultures of Acetobacter xylinum, together with traces of their C(36) homologues.
      These substances were found to be hopane derivatives substituted by a five-carbon
      chain bearing four vicinal hydroxyl groups. For the parent hydrocarbon the term
      bacteriohopane is proposed. The elucidation of the structures utilized high
      resolution mass spectrometry of the terpenes, degradation to C(32) hydrocarbons
      and detailed mass-spectrometric comparison of these with C(32) hydrocarbons
      synthesized from known pentacyclic triterpenes. High-resolution mass-spectral
      data of the terpenes are presented. N.m.r. data are in agreement with the
      proposed structures, which are further supported by the isolation from the same
      organism of 22-hydroxyhopane and derivative hopene(s).

PMID- 4359919
TI  - The nature of the electrophoretically separable multiple forms of rat liver
      monoamine oxidase.
AB  - 1. Treatment of a partly purified preparation of rat liver monoamine oxidase with
      the chaotropic agent sodium perchlorate caused the enzyme to migrate as a single
      band of activity of polyacrylamide-gel electrophoresis, whereas the untreated
      enzyme separated into a number of bands. 2. Treatment with the chaotropic agent
      caused no loss of enzyme activity towards benzylamine, dopamine or tyramine. 3.
      The activities of the untreated preparation towards different substrates were
      inhibited to different extents by heat treatment and by some inhibitors. No such
      differences could be detected after the enzyme preparation had been treated with
      sodium perchlorate. 4. Lipid material, which could be separated by gel
      filtration, was liberated from the enzyme preparation by sodium perchlorate
      treatment. 5. The molecular weight of the treated enzyme was found to be 380000+/
      38000. 6. Perchlorate treatment altered the solubility of the enzyme. 7. A
      continuous assay method for monoamine oxidase is described.

PMID- 4359920
TI  - The structure of a beta-(1 leads to 3)-D-glucan from yeast cell walls.
AB  - Yeast glucan as normally prepared by various treatments of yeast (Saccharomyces
      cerevisiae) cell walls to remove mannan and glycogen is still heterogeneous. The
      major component (about 85%) is a branched beta-(1-->3)-glucan of high molecular
      weight (about 240000) containing 3% of beta-(1-->6)-glucosidic interchain
      linkages. The minor component is a branched beta-(1-->6)-glucan. A comparison of
      our results with those of other workers suggests that different glucan
      preparations may differ in the degree of heterogeneity and that the major beta-(1
      ->3)-glucan component may vary considerably in degree of branching.

PMID- 4359921
TI  - The purification and regulatory properties of alpha-oxoglutarate dehydrogenase
      from Acineobacter iwoffi.
AB  - The alpha-oxoglutarate dehydrogenase multienzyme complex was purified from
      Acinetobacter lwoffi to a high degree of homogeneity as shown by gel
      electrophoresis and analytical ultracentrifugation. Sedimentation-velocity
      analyses gave s(20,w) values which increased with increasing protein
      concentration, suggesting dissociation of the complex in dilute solution. The
      maximum s(20,w) value thereby obtained and the value determined by active enzyme
      centrifugation were both in the range 28-29S. Electron micrographs of the complex
      indicated a molecular diameter of 20-22nm (200-220A). The overall activity of the
      complex was inhibited by NADH, and kinetic studies indicated sites of action on
      the first and third enzyme components. AMP and ADP relieved this inhibition and
      also stimulated enzyme activity. Assays specific for the first enzyme component
      showed this to be the site of action of the adenylates. The activity of the
      complex varied with energy charge in a manner consistent with its role in energy
      metabolism.

PMID- 4359922
TI  - Evidence that chick tendon procollagen must be denatured to serve as substrate
      for proline hydroxylase.
AB  - The ability of chick-embryo proline hydroxylase to hydroxylate [(14)C]proline
      labelled procollagen was investigated between 23 degrees and 37 degrees C. The
      amount of hydroxy[(14)C]proline that could be formed increased sharply between 26
      degrees and 30 degrees C. This corresponded to the temperature interval in which
      the [(14)C]procollagen substrate was thermally denatured, and the results
      therefore indicate that only denatured molecules can be hydroxylated.

PMID- 4359923
TI  - The kinetics of the interconversion of intermediates of the reaction of pig
      muscle lactate dehydrogenase with oxidized nicotinamide-adenine dinucleotide and
      lactate.
AB  - Oxamate competes with pyruvate for the substrate binding site on the E(NADH)
      complex of pig skeletal muscle lactate dehydrogenase. When this enzyme was mixed
      with saturating concentrations of NAD(+) and lactate in a stopped-flow rapid
      reaction spectrophotometer there was no transient accumulation of enzyme
      complexes with the reduced nucleotide. The steady-state rate of formation of free
      NADH was reached within the dead-time of the instrument (3ms). When oxamate was
      added to inhibit the steady state and to uncouple the equilibration: [Formula:
      see text] through the rapid formation of E(NADH) (Oxamate), the rate of formation
      of E(NADH) could be measured by observation of the first turnover. This pH
      dependent transient is controlled by the rate of dissociation of pyruvate and the
      fraction of the enzyme in the form E(NADH) (Pyruvate).

PMID- 4359924
TI  - Editorial: New assays for old.

PMID- 4359925
TI  - Nervous system involvement in ankylosing spondylitis.
AB  - In a review of 45 patients with ankylosing spondylitis 10 had neurological
      symptoms and signs and three of them had two separate neuropathological
      disorders. The neurological profiles fell into five main categories-multiple
      sclerosis, the cauda equina syndrome, focal epilepsy, vertebrobasilar
      insufficiency, and peripheral nerve lesions. An association between ankylosing
      spondylitis and multiple sclerosis is suggested, possibly due to an immunological
      defect or to one being a complication of the other.

PMID- 4359927
TI  - [Some patterns in the distribution of enteroviruses in sewage].

PMID- 4359926
TI  - Changes in antigenic nature of lymphocytes caused by common viruses.
AB  - Healthy human lymphocytes were incubated in the presence of influenza
      A2/Singapore/57, herpes simplex type 1, or adenovirus type 2. After two days the
      cultures were inactivated by irradiation. Fresh lymphocytes taken from the same
      donor were then found to react to the virus-treated cells in short-term cultures.
      We suggest that this reactivity is due to a change in the surface characteristics
      of the lymphocytes brought about by the presence of the virus. This may account
      for anomalous reactions in mixed lymphocyte cultures, and a similar effect in
      vivo might cause accelerated graft rejection.

PMID- 4359928
TI  - Repression, interference, and field dependence as factors in dream forgetting.

PMID- 4359929
TI  - Determination of iron in low-iron diets by colorimetric and atomic absorption
      procedures.

PMID- 4359930
TI  - Gas-liquid chromatographic method for the determination of dimethoate and
      dimethoxon residues in plant and animal tissues, milk, and eggs.

PMID- 4359931
TI  - The rapid chromatographic analysis of the free nucleotides from rat brain.

PMID- 4359932
TI  - Simple separation of neutral lipid classes with two dimensional thin-layer
      chromatography.

PMID- 4359933
TI  - Separation of mammalian neutral lipids by chromatography on glass-fiber paper
      impregnated with silica gel.

PMID- 4359934
TI  - The rapid liquid chromatographic analysis of mixtures of 5'-nucleotides and
      mixtures of flavin nucleotides and 5'-AMP.

PMID- 4359935
TI  - Application of vapor phase chromatography to the quantitative determination of
      conjugated estrogens in drugs.

PMID- 4359937
TI  - Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in
      plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and
      degradation in human erythrocytes.
AB  - The plasma pyridoxal-5'-phosphate (PLP) level of alcoholic subjects has been
      compared with that of non-alcoholic individuals in order to ascertain the
      incidence of abnormal vitamin B(6) metabolism in chronic alcohol abuse. 66
      alcoholic subjects were selected on the basis that they did not exhibit abnormal
      liver function tests and hematologic findings. 35 of them had plasma PLP
      concentrations less than 5 ng/ml, the lowest value encountered in 94 control
      subjects, indicating a high incidence of deranged PLP metabolism in alcoholic
      patients even when hepatic and hematologic abnormalities are absent. The
      biochemical basis for the altered PLP metabolism in chronic alcohol abuse was
      examined. Low plasma PLP levels in alcoholics were not accompanied by decreased
      pyridoxal kinase and pyridoxine phosphate oxidase activities in erythrocytes.
      Further studies with erythrocytes demonstrated that the cellular content of PLP
      is determined not only by the activities of these PLP-synthesizing enzymes but
      also by the activity of a phosphate-sensitive, membrane-associated, neutral
      phosphatase, which hydrolyzes phosphorylated B(6) compounds.Acetaldehyde, but not
      ethanol, impaired the net formation of PLP from pyridoxal, pyridoxine, and
      pyridoxine phosphate by erythrocytes. However, when the B(6)-phosphate
      phosphatase activity was inhibited by 80 mM phosphate, this effect of
      acetaldehyde was abolished. By the use of broken cell preparations, it was
      possible to demonstrate directly that the action of acetaldehyde is mediated by
      the phosphatase, resulting in an acceleration of the degradation of the
      phosphorylated B(6) compounds in erythrocytes.

PMID- 4359936
TI  - Reversal of cyclic AMP-mediated intestinal secretion by ethacrynic acid.
AB  - Ethacrynic acid (EA) has been reported to reduce cholera toxin-induced intestinal
      fluid secretion in the intact animal. We explored the nature of this inhibition
      in vitro by measuring unidirectional, transmural fluxes of (22)Na and (36)Cl
      across isolated rabbit ileal mucosa. Under control conditions (short-circuited
      mucosa bathed in bicarbonate-Ringer), there was net absorption of Na and Cl.
      Theophylline (10 mM), cyclic AMP (5 mM), and cholera toxin (added in vivo)
      abolished net Na flux and produced net Cl secretion. In the presence of either
      theophylline or cAMP, addition of 0.1 mM EA to the serosal bathing solution
      abolished net Cl secretion and restored net Na absorption. Cholera toxin-treated
      mucosa was exposed to 0.05 and 1.0 mM EA. The lower concentration restored net Na
      absorption but did not significantly reduce Cl secretion. The higher
      concentration abolished net transport of both Na and Cl. Short-circuit current
      and Na flux measurements in the presence and absence of glucose indicated that
      0.1 mM EA does not inhibit glucose-coupled Na transport. Short-circuit current
      measurements in the presence of 1.0 mM EA suggested that even this concentration
      of EA does not inhibit glucose-coupled Na transport. Thus EA appears to
      specifically inhibit Cl (or NaCl) secretion without inhibiting the absorptive Na
      "pump." The anti-secretory effect of 0.1 mM EA does not appear to result from
      inhibition of adenylate cyclase since secretion stimulated by addition of 5 mM
      cAMP was abolished. Furthermore, 0.1 mM EA did not significantly reduce
      theophylline-augmented and cholera toxin-augmented cAMP levels in ileal mucosa.
      We conclude that EA interacts specifically with the active Cl (or NaCl) secretory
      mechanism of the small intestine at a step beyond generation of cAMP.

PMID- 4359938
TI  - Direct inhibitory effect of hypercalcemia on renal actions of parathyroid
      hormone.
AB  - The effects of calcium on the renal actions of parathyroid hormone (PTH) were
      studied in vivo and in vitro. In parathyroidectomized rats, variable levels of
      blood calcium concentration were induced by intravenous infusion of calcium. The
      renal responses to the injected PTH, i.e. phosphate and cyclic AMP excretion,
      were compared in these animals. After PTH injection, the increases of both
      phosphate and cyclic AMP excretion were less in the calcium-infused animals than
      in the control group without calcium infusion. There was an inverse correlation
      between the renal responses to PTH and plasma calcium concentration of 4.2-13.5
      mg/100 ml. But calcium had no effect on phosphate excretion induced by infusion
      of dibutyryl cyclic AMP. In the in vitro experiments, the increase of cyclic AMP
      concentration in response to PTH was less in renal cortical slices taken from the
      calcium-infused animals than in ones from the control group without calcium
      infusion. Calcium also inhibited the activation of renal cortical adenylate
      cyclase in response to PTH, but calcium had no effect on phosphodiesterase. The
      data indicate that calcium directly inhibits renal actions of PTH both in vivo
      and in vitro. Such inhibitory mechanism is probably at or before the step of PTH
      dependent cyclic AMP generation in the kidney.

PMID- 4359939
TI  - Study of the renal tubular interactions of thyrocalcitonin, cyclic adenosine
      3',5'-monophosphate, 25-hydroxycholecalciferol, and calcium ion.
AB  - Acute clearance studies were performed in thyroparathyroidectomized animals to
      determine the actions and interactions of thyrocalcitonin (TCT), cyclic adenosine
      3'5'-monophosphate (cAMP), 25-hydroxycholecalciferol (25HCC), and calcium ion on
      the reabsorption of phosphate, calcium, sodium, and potassium by the kidney. The
      infusion of 25HCC in a dosage of 60 U/h to moderately saline-expanded animals
      (2.5% body weight) induced a fall in the excretion of all of the ions under study
      after 90-120 min similar to that observed in previous experiments from this
      laboratory. Mean decrements in fractional excretion were: phosphate, 42.0% (P <
      0.005); calcium, 25.0% (P < 0.005); sodium, 23.4% (P < 0.001); and potassium,
      14.7% (P < 0.005). The superimposition of either porcine or salmon TCT (1-100 MRC
      U/h for 2 h) resulted in no further alterations in electrolyte excretion.
      However, the infusion of TCT during steady-state saline expansion, before the
      administration of 25HCC, obviated the renal transport effects of the vitamin D
      metabolite. Both in the latter studies, as well as those in which similar doses
      of TCT were given to hydropenic animals, the hormone itself failed to induce any
      consistent alteration in electrolyte excretion. Cyclic AMP (50 mg/h) caused an
      increase in the excretion of phosphate, sodium, and potassium and no change in
      calcium excretion. Like TCT, the nucleotide blocked the action of 25HCC on the
      kidney. Raising the mean level of serum ultrafilterable calcium to 3.02+/-0.25
      mEq/liter from 1.62+/-0.17 mEq/liter likewise prevented enhanced ionic
      reabsorption due to 25HCC.

PMID- 4359940
TI  - Effects of ethacrynic acid on the isolated collecting tubule.
AB  - Effects of the diuretic ethacrynic acid on osmotic water permeability were
      investigated in the isolated perfused collecting tubule of the rabbit kidney. The
      base-line water permeability of the collecting tubule was not affected when the
      drug (10(-4)M) alone was added to the bathing medium. Vasopressin alone in the
      bathing medium (2, 5 muU/ml) elicited a significant increase in osmotic water
      absorption. With vasopressin kept in the bathing medium, the addition of 10(-5)M
      ethacrynic acid depressed the hydro-osmotic effect of vasopressin by 50%. This
      inhibitory effect of low concentrations of ethacrynic acid could be surmounted by
      high, supramaximal dosage levels of vasopressin. When 10(-4)M ethacrynic acid was
      added to the bathing medium before vasopressin, the hydro-osmotic effect of
      vasopressin and the diuretic in combination was insignificant.Dibutyryl adenosine
      3'5'-monophosphate (10(-4)-10(-2)M) alone in the bathing medium significantly
      increased baseline osmotic water flow, mimicing the effect of antidiuretic
      hormone. When ethacrynic acid was added together with the nucleotide, the
      permeability remained at the same high level. Theophylline, like the nucleotide
      and vasopressin, produced a significant hydro-osmotic effect. The magnitude of
      this response was not affected by further addition of ethacrynic acid (10(-4)M).
      It was concluded that ethacrynic acid is an antagonist of antidiuretic hormone.
      The antagonism probably occurs at the level of the receptor site of the hormone
      on the peritubular membrane. Antagonism to circulating antidiuretic hormone may
      therefore be one of the factors involved in the loss of renal concentrating
      ability brought about by ethacrynic acid diuresis.

PMID- 4359942
TI  - Ultrastructure of taper hepatoma ascites cells.

PMID- 4359943
TI  - Effects of oestrogen antagonists on mitosis and (3H)oestradiol binding in the
      mouse uterus.

PMID- 4359941
TI  - Effects of prostaglandins and cholera enterotoxin on intestinal mucosal cyclic
      AMP accumulation. Evidence against an essential role for prostaglandins in the
      action of toxin.
AB  - Both cholera enterotoxin and certain prostaglandins have been shown to stimulate
      intestinal fluid secretion in vivo, to cause ion flux changes in vitro similar to
      those caused by addition of cyclic 3',5'-adenosine monophosphate (cyclic AMP),
      and to activate intestinal mucosal adenyl cyclase. It has been suggested that the
      effects of the enterotoxin on intestinal cyclic AMP metabolism may be indirect,
      and that locally synthesized prostaglandins may serve as required intermediates
      for the effects of the enterotoxin in activating intestinal mucosal adenyl
      cyclase. In order to clarify certain aspects of the mechanisms by which these two
      agents alter intestinal mucosal cyclic AMP metabolism and ion transport, their
      effects on cyclic AMP accumulation in rabbit ileal mucosa were examined in vitro.
      Addition of 5 mug per ml (75 mug per 150 mg mucosa) of purified cholera
      enterotoxin produced a peak increase in cyclic AMP level in 3 h but there was a
      time delay of at least 30 min before any effect was observed. Inhibition of
      cyclic nucleotide phosphodiesterase with theophylline failed to reduce this time
      delay. In contrast, addition of prostaglandin E(1) (PGE(1)) increased the cyclic
      AMP level rapidly, a peak effect being observed in 2 min. The time of the peak
      prostaglandin-induced changes in cyclic AMP level and short-circuit current
      correlated closely. A maximal increment in cyclic AMP level was achieved with 5 x
      10(-5) M PGE(1). When 10(-4) M PGE(1) was added to mucosa already maximally
      stimulated with cholera toxin, the resulting cyclic AMP level was equal to the
      sum of the levels reached when each agent was added alone. Furthermore, the
      effects of the enterotoxin on mucosal cyclic AMP levels were not influenced by
      indomethacin under conditions where mucosal prostaglandins synthesis was
      inhibited. The results suggest that endogenous prostaglandins do not provide an
      essential link in the activation of intestinal mucosal adenyl cyclase by cholera
      enterotoxin. The present study also indicates that the effect of cholera
      enterotoxin on intestinal mucosal cyclic AMP metabolism involves a definite time
      delay which is not due to cyclic nucleotide phosphodiesterase activity.

PMID- 4359945
TI  - The mechanism of androgen uptake and concentration by rat ventral prostate in
      organ culture.

PMID- 4359944
TI  - Inhibition by dexamethasone of adrenocorticotrophin and cortisol release induced
      by intravenous infusion of ATP and dibutyryl cyclic AMP in piglets.

PMID- 4359946
TI  - Unwinding of parental strands during simian virus 40 DNA replication.
AB  - Pools of young (less than 60% replicated) and mature (60-90% replicated)
      replicating molecules of simian virus 40 (SV40) DNA have been treated at pH 12.2
      in order to dissociate growing chains from the parental strands. The molecules
      are neutralized so that the parental strands can reassociate and they have then
      been isolated. They are covalently closed structures which sediment rapidly in
      alkaline sucrose gradients; however, the sedimentation rates are less than the
      sedimentation rate of SV40 DNA I. Isopycnic banding in CsCl-ethidium bromide and
      sedimentation velocity studies in the presence of various amounts of ethidium
      bromide indicate that these structures contain negative superhelical turns and
      several-fold-higher superhelix densities than SV40 DNA I (the covalently closed
      DNA molecule). These structures are those that would be predicted if nicking,
      unwinding, and sealing of the parental strands occurred as replication proceeded.
      These experiments provide a direct demonstration that there is a progressive
      decrease in the topological winding number which accompanies SV40 DNA
      replication.

PMID- 4359947
TI  - Genetic and physiological properties of temperature-sensitive mutants of Cocal
      virus.
AB  - Temperature-sensitive (ts) mutants of Cocal virus (VSV Cocal) were isolated after
      treatment with the base analogue mutagen, 5-fluorouracil. These mutants could be
      classified into four mutually complementing groups. Weak complementation was
      detected between certain pairs of VSV Cocal ts mutants and ts mutants of
      vesicular stomatitis virus (VSV) Indiana, but no complementation was observed
      with ts mutants of VSV New Jersey. Two complementing ts mutants of Chandipura
      virus, an unrelated rhabdovirus, did not complement any VSV mutant, Thus, ability
      to complement in the VSV group appears to be correlated with serological
      relationships. The RNA and protein-synthesizing capacities of these ts mutants
      have been determined, and it is possible to establish a correspondence between
      the VSV Cocal and the VSV Indiana complementation groups.

PMID- 4359948
TI  - Phosphorylation of simian virus 40 proteins in a cell-free system.
AB  - We have shown previously that all the structural proteins of simian virus 40
      (SV40) are phosphoproteins. Virus phosphorylated in vivo could be further
      phosphorylated with exogenous cellular protein kinases in a cell-free system
      containing gamma-(32)P-ATP as phosphate donor. In intact infectious virus only
      polypeptides 1 and 2 (mol wt 49,000 and 40,800, respectively) were further
      phosphorylated in vitro. However, when infectious SV40 was partially disrupted,
      treated with nucleases, and then phosphorylated in vitro, all five structural
      polypeptides accepted additional phosphate groups. Similarly, all polypeptides of
      intact empty capsids, derived from infected cells, were further phosphorylated in
      vitro. Phosphorylation of empty capsids and infectious SV40 in vitro was enhanced
      from 4- to 11-fold after prior treatment of virus with alkali. The phosphate
      group was linked only to serine residues of the viral polypeptides phosphorylated
      both in vitro and in vivo.

PMID- 4359949
TI  - Partial transcription of murine type C viral genomes in BALB c cell lines.
AB  - The mouse cell line, BALB/c 3T3, and its derivatives transformed either
      spontaneously or by treatment with a variety of external agents, were analyzed
      for cytoplasmic RNA complementary to DNA products prepared from the Kirsten
      strain of murine sarcoma-leukemia virus, and from an endogenous type C virus of
      BALB/c 3T3. Although none of these cell lines spontaneously releases complete
      type C virions, they all contain RNA which is partially homologous to a portion
      of the 35S RNA isolated from these viruses. The parental cell line, BALB/c 3T3,
      contains a low level of viral-related RNA, and there is an increased amount of
      this RNA in some of the transformed cells. The RNA detected represents only a
      fraction of the viral RNA found in virus-producing cells. The formation of
      RNA:DNA hybrids was detected by equilibrium centrifugation in Cs(2)SO(4) density
      gradients and by analysis with a single-strand-specific nuclease from Aspergillus
      oryzae. Viral DNA products prepared either from an endogenous reaction with whole
      virus in the presence of actinomycin D or from purified 70S viral RNA as template
      using avian myeloblastosis virus DNA polymerase yield comparable data. In
      addition, all of the BALB/c lines examined produce detectable levels of murine
      type C virus group-specific antigen.

PMID- 4359951
TI  - Reassortment of simian virus 40 DNA during serial undiluted passage.
AB  - Alterations occur in the supercoiled form of viral DNA after the serial undiluted
      passaging of simian virus (SV) 40. We have identified a portion of the viral
      genome which is amplified during this process. These SV40 DNA sequences represent
      about 30% of the viral genetic information and are present in a reiterated form
      in twisted circular molecules prepared from purified virions. In addition,
      reiterated and unique green monkey DNA sequences are incorporated into
      supercoiled viral DNA. The cellular DNA appears to be inserted at numerous
      locations in the DNA I molecules.

PMID- 4359952
TI  - Separation of Herpes simplex virus-induced antigens by Concanavalin A affinity
      chromatography.
AB  - Biologically active herpes simplex virus (HSV)-induced antigens were selectively
      removed from extracts of infected BHK cells by affinity chromatography by
      utilizing an insoluble form of concanavalin A (Con A). Soluble extracts of (3)H
      glucosamine-labeled, HSV-infected cells were absorbed to a Con A column. Bound
      material was eluted with alpha-methyl-d-mannoside (alphaMM) and NaCl. The
      specific activity of the eluted glycoproteins increased by 10-fold. Two broad
      groups of viral-induced antigens were isolated from Con A. Group I includes two
      antigens which bind to Con A by a specific mechanism because the antigens are
      dissociated by alphaMM. Group II contains three antigens which bind to Con A but
      apparently by a nonspecific or electrolytic mechanism. One antigen in group I was
      identified as the glycoprotein antigen, CP-1, described previously.

PMID- 4359950
TI  - Integrated state of oncornavirus DNA in normal chicken cells and in cells
      transformed by avian myeloblastosis virus.
AB  - The covalent linkage of oncornavirus-specific DNA to chicken DNA was investigated
      in normal chicken embryo fibroblasts (CEF) and in virus-producing leukemic cells
      transformed by avian myeloblastosis virus (AMV). The virus-specific sequences
      present in cellular DNA fractionated by different methods were detected by DNA
      RNA hybridization by using 70S AMV RNA as a probe. In CEF and in leukemic cells,
      the viral DNA appeared to be present only in the nucleus. After cesium chloride
      ethidium bromide density equilibrium sedimentation, the viral DNA was present as
      linear, double-stranded molecules not separable from linear chicken DNA. After
      extraction by the Hirt procedure, the viral DNA precipitated with the high
      molecular-weight DNA. After alkaline sucrose velocity sedimentation, the viral
      DNA cosedimented with the high-molecular-weight cellular DNA. The results
      indicate that in both types of cells studied, the oncornavirus-specific DNA
      sequences were linked by alkali stable bonds to nuclear cellular DNA of high
      molecular weight and did not appear to be present in free form of any size.

PMID- 4359954
TI  - Comparison of in vitro and cell-mediated alteration of a human Rhinovirus and its
      inhibition by sodium dodecyl sulfate.
AB  - After human rhinovirus type 2 (HRV-2) attaches to HeLa cells, two types of
      subviral particles are formed which closely resemble particles produced in vitro
      by acid or heat. One type of particle contains RNA whereas the second sediments
      as an empty capsid and is RNA-deficient. Sodium dodecyl sulfate (SDS) at 10(-4) M
      inhibits the cell-mediated formation of these particles from HRV-2 virions and
      the ability of HRV-2 to form plaques, but it does not inhibit the formation of
      plaques by human rhinovirus 14 (HRV-14). SDS also stabilizes HRV-2 against
      inactivation by acid or heat to a much greater extent than it does HRV-14. In a
      similar manner, SDS protects against the acid inactivation of the subpopulation
      of HRV-2 natural top component particles which attach to virus-specific cellular
      receptors. This suggests that the loss of native properties of natural top
      component particles and of virion are related processes. The basis for this
      alteration and also its role in infection are discussed.

PMID- 4359953
TI  - SP62, a viable mutant of bacteriophage T4D defective in regulation of phage
      enzyme synthesis.
AB  - SP62 is a mutant of bacteriophage T4D that was discovered because it produces
      fewer phage than the wild type in the presence of 5-fluorodeoxyuridine. In the
      absence of phage DNA synthesis, SP62 solubilizes host DNA slower than normal;
      this may explain the sensitivity to 5-fluorodeoxyuridine. In Escherichia coli B
      at 37 C in the absence of drugs, SP62 makes DNA at a normal rate and the kinetics
      of appearance of phage are nearly normal. Under the same conditions, SP62
      produces T4 lysozyme (gene e) at a normal rate until 20 min, but then produces it
      at twice the normal rate until at least 60 min. It has long been known that, when
      T4 DNA synthesis is blocked (DNA(-) state) in an otherwise normal infection, the
      synthesis of a number of early enzymes continues beyond the shutoff time of about
      12 min seen in the DNA(+) state, but still stops at about 20 min. We have termed
      the 12-min shutoff event S1 and the 20-min shutoff event S2. We show here that,
      in the DNA(+) state, SP62 makes four early enzymes normally, i.e., S1 occurs.
      However, in the DNA(-) state (where S1 is missing), SP62 continues to make
      dCTPase (gene 56), dCMP hydroxymethylase (gene 42), and deoxynucleotide kinase
      (gene 1) for at least an hour; this results in production of up to 13 times the
      normal level of dCTPase at 60 min after infection, or 6 times the DNA(-) level.
      We conclude that SP62 is defective in the second shutoff mechanism, S2, for these
      three enzymes. In contrast, SP62 causes premature cessation of dTMP synthetase
      production in the DNA(-) state; the result is a twofold underproduction of dTMP
      synthetase. Autoradiograms of pulse-labeled proteins separated by slab-gel
      electrophoresis in the presence of sodium dodecyl sulfate show that a number of
      other T4 early proteins, including the products of genes 45, 46, and rIIA, are
      synthesized longer than normal by SP62 in the DNA(-) state. Few late proteins are
      made in the DNA(-) state, but in autoradiograms examining the DNA(+) state there
      is little or no effect of the SP62 mutation on the synthesis of T4 late or early
      proteins. Circumstantial evidence is presented favoring a role for the gene of
      SP62 in translation of certain mRNAs. At very high temperatures (above 43 C) in
      the absence of drugs, phage production, but not DNA synthesis, is much reduced in
      SP62 infections relative to wild-type T4 infections; this temperature sensitivity
      is greater on E. coli CR63 than on E. coli B. This property has facilitated
      recognition of the SP62 genotype and aided in complementation testing and genetic
      mapping. A later publication will provide evidence that SP62 defines a new T4
      gene named regA, which maps between genes 43 and 62.

PMID- 4359955
TI  - Polypeptide composition of Influenza B viruses and enzymes associated with the
      purified virus particles.
AB  - Influenza B/LEE/40, B/Rome/1/67, B/Hong Kong/8/73, and B/Victoria/98926/70
      viruses have a similar polypeptide composition as analyzed by sodium dodecyl
      sulfate polyacrylamide gel electrophoresis. These viruses are composed of six or
      seven polypeptides, depending on whether one or two high-molecular-weight
      polypeptides are resolved, ranging in molecular weights from 27,000 to 90,400.
      Three of these polypeptides, namely the heavy and light hemagglutinin chains and
      the neuraminidase, have attached carbohydrate. Highly purified influenza B/LEE/40
      and B/Rome/1/67 virus preparations have RNA-dependent RNA polymerase activity
      equivalent to the incorporation of 100 and 30 pmol, respectively, of (3)H-UMP per
      mg of virus protein per h at 37 C, which is demonstrated only in detergent
      treated virus suspensions. However, no RNA-dependent DNA polymerase enzyme
      activity was detected in the two viruses although virus suspensions were
      "activated" by heat, alpha-chymotrypsin, and detergents. Other enzymatic
      activities were associated with purified preparations of influenza B virus and
      were attributed to minor contamination of virus with host cell enzymes. Thus,
      nucleoside and deoxynucleoside phosphohydrolase enzymes were active in the
      absence of detergents and catalyzed the release of 1,200 and 1,800 nmol of P(i)
      per mg of virus protein in 30 min at 37 C from ATP and dATP substrates. Thin
      layer chromatography indicated that the products of the phosphohydrolase enzymes
      of influenza B/LEE/40 were mainly nucleoside diphosphate and monophosphate. The
      latter enzymes were tightly bound to influenza B/LEE/40 virus and could not be
      removed completely by repeated centrifugation, including centrifugation of the
      virus to equilibrium in density gradients of 25 to 40% (wt/vol) cesium chloride.
      A low degree of RNase (approximately 0.01 mug% contamination) and phosphatase (10
      30 nmol of P(i) released per mg of virus protein per 30 min) activity was
      detected in some, but not all, influenza B/LEE/40 virus preparations.

PMID- 4359956
TI  - Studies of nondefective Adenovirus 2-Simian virus 40 hybrid viruses. 8.
      Association of Simian virus 40 transplantation antigen with a specific region of
      the early viral genome.
AB  - Two of the five nondefective adenovirus 2 (Ad2)-simian virus 40 (SV40) hybrids
      induce SV40 transplantation resistance in immunized hamsters. These two hybrids,
      Ad2(+)ND(2) and Ad2(+)ND(4), contain 32 and 43% of the SV40 genome, respectively.
      The pattern of induction of SV40 transplantation antigen (TSTA) by the various
      hybrids differentiates TSTA from both SV40 U and T antigens. Since the SV40 RNA
      induced by both these hybrids is early SV40 RNA, these findings confirm that TSTA
      is an early SV40 function. By combining available data on SV40 antigen induction
      by these hybrids with electron microscopy heteroduplex mapping studies, the DNA
      segment responsible for the induction of SV40 TSTA can be inferred to lie in the
      region between 0.17 and 0.43 SV40 units from the site on the SV40 chromosome
      cleaved by E. coli R(1) restriction endonuclease.

PMID- 4359957
TI  - Properties of nucleoprotein complexes containing replicating polyoma DNA.
AB  - Short-lived nucleoprotein complexes (r-py complex) containing replicating polyoma
      DNA were isolated from infected cells after lysis with Triton X-100. The Triton
      lysing procedure of Green, Miller, and Hendler (1971) releases most complexes
      containing supercoiled viral DNA (py complex) from nuclei, but liberates only a
      portion of r-py complexes. r-py Complexes are associated more strongly with
      nuclear sites but can be extracted by prolonged incubation of nuclei in lysing
      solution. Complexes containing replicating polyoma DNA appear to be precursors to
      stable complexes containing supercoiled DNA. Sedimentation and buoyant density
      studies indicate that protein is bound to both r-py complexes and py complexes at
      a ratio of protein to DNA of about 1 to 2/1. Both types of complexes sediment as
      if the viral DNA is more compact than free DNA and both undergo major reversible
      configurational changes with increased salt concentration. Changes resulting from
      enzymatic and chemical treatment indicate that there may be two or more protein
      components in both r-py complex and py complex. One component is digested by
      Pronase and trypsin while another is resistant to the enzymes but released by
      deoxycholate. The abundance and similarity in chemical and physical properties of
      protein bound to all forms of polyoma DNA suggest that part of the protein
      molecules may serve in a structural capacity.

PMID- 4359958
TI  - Nucleoprotein complexes containing replicating Simian virus 40 DNA: comparison
      with polyoma nucleoprotein complexes.
AB  - Procedures for isolating nucleoprotein complexes containing replicating polyoma
      DNA from infected mouse cells were used to prepare short-lived nucleoprotein
      complexes (r-SV40 complexes) containing replicating simian virus 40 (SV40) DNA
      from infected monkey cells. Like the polyoma complexes, r-SV40 complexes were
      only partially released from nuclei by cell lysis but could be extracted from
      nuclei by prolonged treatment with solutions containing Triton X-100. r-SV40
      complexes sedimented faster than complexes containing SV40 supercoiled DNA (SV40
      complex) in sucrose gradients, and both types of SV40 nucleoprotein complexes
      sedimented ahead of polyoma complexes containing supercoiled polyoma DNA (py
      complex). The sedimentation rates of py complex and SV40 complex were 56 and 61S,
      respectively, based on the sedimentation rate of the mouse large ribosomal
      subunit as a marker. r-SV40 complexes sedimented as multiple peaks between 56 and
      75S. Sedimentation and buoyant density measurements indicated that protein is
      bound to all forms of SV40 DNA at about the same ratio of protein to DNA (1-2/1)
      as was reported for polyoma nucleoproteins.

PMID- 4359959
TI  - Herpes simplex virus and human cytomegalovirus replication in WI-38 cells. I.
      Sequence of viral replication.
AB  - A comparison, under standardized conditions, of herpes simplex virus (HSV) and
      human cytomegalovirus (CMV) revealed differences in viral morphology, in the
      timing of their infectious cycles, and in several morphological events during
      those cycles. Structural distinctions between the two viruses included the
      coating of unenveloped cytoplasmic CMV capsids, but not those of HSV, and a
      variation in the structure of their cores. Since the two cycles were carried out
      in the same host cell strain under conditions of one-step growth (input
      multiplicity = 10 PFU/cell), it was possible to construct time scales locating
      the major events of each cycle. Comparison of the two showed that HSV replicated
      and released progeny within 8 h postinfection, whereas CMV required 4 days. These
      results correlated well with those of concurrent plaque assays. Within the longer
      CMV cycle, most of the major events appeared retarded to a similar degree, and no
      obvious limiting step in particle production could be identified. Distinctions
      between the two cycles included the following: condensation of the chromatin in
      HSV- but not CMV-infected cells; the greater tendency of HSV to produce membrane
      alterations; and the appearance of cytoplasmic dense bodies in CMV- but not HSV
      infected cells. Identification of these differences even under identical
      conditions of culture and infection strongly implies that they result from
      intrinsic differences in the nature of the viruses, and are not caused by
      variations in experimental conditions.

PMID- 4359961
TI  - Factors affecting cell fusion induced by Sendai virus.
AB  - Cell fusion mediated by exogenous Sendai virus appears to occur in four
      temperature-dependent stages. The first two, which include viral adsorption, are
      pH dependent and can be inhibited by viral antibody. Viral envelope constituents
      remain detectable on the cell surface during the third stage and disappear only
      when cell-to-cell fusion supervenes. The relationship of these interactions to
      possible mechanisms of cell fusion are discussed.

PMID- 4359960
TI  - Properties of noninfectious and transforming viruses released by Murine sarcoma
      virus-induced hamster tumor cells.
AB  - The cell culture lines HTG2 and HTG3 were established from a transplantable
      hamster tumor induced by a murine sarcoma virus (strain Gz-MSV) after 17 and 60
      in vivo passages, respectively. The viruses released by these two cell lines
      markedly differ in morphology, antigenic composition, infectivity, transforming
      ability, and enzymatic activity. HTG2 virions contained the sarcoma genome but
      were noninfectious for mouse and hamster cells (S+H-virus). HTG3 virions
      transformed hamster but not mouse cells. Whereas HTG2 cells and its virus
      contained murine type C virus gs-1 antigen, all HTG3 clonal lines expressed both
      murine and hamster type C virus gs-1 antigens. The RNA-dependent DNA polymerase
      activity of HTG2 virus was very low, whereas that of HTG3 virus was relatively
      high. HTG2 virions contained electron-lucent centers only. HTG3 virus consisted
      of the expected mixture of virions with electron-dense and electron-lucent
      centers. Many broken or incomplete virions were present in both viruses. HTG2
      virus is a noninfectious "defective" sarcoma virus without detectable helper
      virus. Data obtained in these experiments suggest that HTG3 virus is a hamster
      type C virus pseudotype of Gz-MSV (Gz-MSV [HaLV]). The genome of Gz-MSV is
      capable of antigenic expression in heterologous cells and in the presence of
      heterologous viruses. Attempts to chemically activate hamster type C virus (HaLV)
      from HTG2 cells were unsuccessful. The HTG1 cell culture line, established from
      another Gz-MSV-induced hamster tumor, initially released a virus
      indistinguishable from the HTG2 virus. After in vitro passage, spontaneous
      activation of HaLV occurred in HTG1 cells, and the resultant Gz-MSV (HaLV) had
      properties similar to those of the HTG3 virus.

PMID- 4359962
TI  - Induction of cellular DNA synthesis by the nondefective Adenovirus 2-Simian virus
      40 hybrid viruses.
AB  - Induction of cellular DNA synthesis by the nondefective adenovirus 2-simian virus
      40 hybrid viruses was examined in monkey and hamster cells. It was not possible
      to discriminate the effects of the hybrid viruses from those of wild-type
      adenovirus 2.

PMID- 4359963
TI  - Denitrification in granular carbon and sand columns.

PMID- 4359964
TI  - Defective superoxide production by granulocytes from patients with chronic
      granulomatous disease.

PMID- 4359965
TI  - Health-services information systems in the United States today.

PMID- 4359966
TI  - Letter: Acute hemorrhagic cystitis due to adenovirus Type II.

PMID- 4359967
TI  - Renal function in pregnancy.

PMID- 4359968
TI  - Influence of malignant cells on the healing of colonic anastomoses: experimental
      observations.

PMID- 4359969
TI  - Generalized eruptive histiocytoma.

PMID- 4359971
TI  - [Poliomyelitis in Poland in the years 1971-1972].

PMID- 4359972
TI  - Toward a theory of dream recall.

PMID- 4359973
TI  - [Experience in feto-oleography].

PMID- 4359970
TI  - The sodium story: effects of anaesthesia and surgery on intrarenal mechanisms
      concerned with sodium homeostasis.

PMID- 4359974
TI  - [Free blood serum amino acids in children with epidemic hepatitis (Botkin's
      disease)].

PMID- 4359975
TI  - [Characteristics of a cholestatic variant of epidemic hepatitis].

PMID- 4359977
TI  - [Morphological changes in certain types of conjunctivitis].

PMID- 4359976
TI  - Adrenalectomy for metastatic carcinoma of the breast. Experience in a community
      hospital.

PMID- 4359978
TI  - 1971 Yant Memorial Lecture. Mining: problems and progress in industrial hygiene.

PMID- 4359979
TI  - Adenine arabinoside therapy in corneal stromal disease and iritis due to herpes
      simplex.

PMID- 4359980
TI  - Inhibition by plant growth retardants of cholesterol biosynthesis in slices of
      rat liver and hepatoma.

PMID- 4359981
TI  - Effect of oestradiol-3,17beta dipropionate on spermatogenesis and lysosomal
      enzymes in the rat testis.

PMID- 4359982
TI  - Experience with a short test of pituitary-adrenal function.

PMID- 4359983
TI  - A passive haemagglutination test for the demonstration of antibody to infectious
      bovine rhinotracheitis-infectious pustular vulvovaginitis virus. 2. Studies on
      antibody incidence and the serological response after infection.

PMID- 4359984
TI  - The treatment of some neoplastic diseases in children with a new cytostatic drug:
      peptichemio. Investigations of a possible interference with lymphocyte
      blastogenesis and chromosomes.

PMID- 4359986
TI  - Effect of EGTA on protein release and cyclic AMP accumulation in rat parotid
      gland.

PMID- 4359985
TI  - Cyclic 3',5'-adenosine monophosphate dependent protein kinase from dog prostate.

PMID- 4359987
TI  - The physiology of prostaglandins.

PMID- 4359988
TI  - Comparative aspects of equine herpesviruses.

PMID- 4359990
TI  - Studies on 1-beta-D-arabinofuranosyl-cytosine-resistant mutants of Chinese
      hamster fibroblasts. A mitochondrial deoxycytidine kinase devoid of activity on
      arabino-cytosine.

PMID- 4359989
TI  - Induction of polyoma DNA synthesis by injection into frog-egg cytoplasm.

PMID- 4359992
TI  - 2-Amino-2,6-dideoxy-d-glucose (D-quinovosamine): a constituent of the
      lipopolysaccharides of Vibrio cholerae.

PMID- 4359991
TI  - Effects of 5'-amido analogues of adenosine 3':5'-monophosphate and adenosine
      3':5'-monophosphothioate on protein kinase, binding protein and
      phosphodiesterases.

PMID- 4359993
TI  - A nuclear-magnetic-resonance study of the manganese-thiamine-pyrophosphate
      complex in solution.

PMID- 4359994
TI  - Studies on the induction of nitrate reductase by nitrite in bean-seed cotyledons.

PMID- 4359995
TI  - Clinical evaluation of indoramin, a new antihypertensive agent.

PMID- 4359996
TI  - [The scope and limitations of xero-radiography of the breast. A current review
      (author's transl)].

PMID- 4359997
TI  - [Changes in lymphatic flow produced by blocking the thoracic duct by means of an
      endo-oesophageal balloon catheter (author's transl)].

PMID- 4359998
TI  - [The lymphographic demonstration of mediastinal lymph nodes in man by endo
      oesophageal obstruction of the thoracic duct (author's transl)].

PMID- 4359999
TI  - [Evaluation of endo-lymphatic therapy of the VX2 tumour in the rabbit.
      Investigations using the beta-ray source P 32-tri-N-octyl-phosphate and the gamma
      source I 125-trioleine (author's transl)].

PMID- 4360000
TI  - [Dysplasia cleido-cranialis].

PMID- 4360001
TI  - [The metacarpal sign (author's transl)].

PMID- 4360002
TI  - [Neonates with diastrophic, thanatophoric dwarfism and pre-natal bowing of the
      long tubular bones (author's transl)].

PMID- 4360004
TI  - [Selective arteriography of a sequestrated lung (author's transl)].

PMID- 4360003
TI  - [Segmental, saccular dilatation of the intra-hepatic bile ducts; the so-called
      Caroli syndrome (author's transl)].

PMID- 4360005
TI  - [The angiographic demonstration of an extra-lobar sequestration (author's
      transl)].

PMID- 4360006
TI  - [Tricuspid and pulmonary valve calcification with an atrial septal defect
      (author's transl)].

PMID- 4360007
TI  - [Symmetrical basal ganglia calcification (Fahr's syndrome) and its differential
      diagnosis (author's transl)].

PMID- 4360008
TI  - [Annular shadows in orbital skiagramm (author's transl)].

PMID- 4360009
TI  - [Case report on the clinical picture of a milk-duct fistula in the mammillary
      secretory disease].

PMID- 4360010
TI  - [Foreign body in the breast simulating a malignant cyst].

PMID- 4360011
TI  - [Traumatic osteolysis of the lateral clavicle].

PMID- 4360012
TI  - [Fibrous dysplasia of the mandible].

PMID- 4360013
TI  - [An epidermoid in the region of the cerebellopontile angle].

PMID- 4360014
TI  - [The differential diagnostic deliberations on the demonstration of abnormal
      contrast media recesses in thoracid myelography].

PMID- 4360015
TI  - [The tracheomegaly].

PMID- 4360016
TI  - [In memoriam Professor Franz Josef Strnad, M.D].

PMID- 4360017
TI  - [Cytology of the interrenal system in the brook lamprey (Lampetra planeri
      Bloch)].

PMID- 4360018
TI  - The lactose system in Klebsiella aerogenes V9A. 3. Specific repression of the lac
      operon by melibiose and raffinose.

PMID- 4360019
TI  - [Therapy with ACTH (corticotropin)--unjustly neglected in Germany].

PMID- 4360020
TI  - Suspected adenoviral infection in adult dairy cattle.

PMID- 4360021
TI  - Effects of bovine viral diarrhea and parainfluenza-3 virus vaccines on
      development of respiratory tract disease in calves.

PMID- 4360023
TI  - Metabolism of endogenous proinsulin and insulin in man.

PMID- 4360022
TI  - Big ACTH: conversion to biologically active ACTH by trypsin.

PMID- 4360024
TI  - Insulin receptors in the plasma membranes of human placenta.

PMID- 4360025
TI  - Cyclic adenosine monophosphate stimulates secretion of human chorionic
      gonadotropin and estrogens by human trophoblast in vitro.

PMID- 4360026
TI  - Complementation of translational defect for growth of human adenovirus type 2 in
      Simian cells by a Simian virus 40-induced factor.

PMID- 4360027
TI  - Rotational relaxation time of concanavalin A bound to the surface membrane of
      normal and malignant transformed cells.

PMID- 4360028
TI  - [Pneumothorax and pneumomediastinum in the newborn infant].

PMID- 4360029
TI  - [Blood and tissue lipids in hypokinetic rats].

PMID- 4360030
TI  - Neurotransmitter uptake: a tool in identifying neurotransmitter-specific
      pathways.

PMID- 4360032
TI  - Nerve sheath myxoma in the tongue.

PMID- 4360031
TI  - Selective inhibition of aldosterone synthesis by 11-hydroxylated spirolactone in
      rat adrenals.

PMID- 4360034
TI  - Radiotherapy for postoperative persistent cancer of the head and neck.

PMID- 4360033
TI  - Surgical management of recurrent head and neck cancer.

PMID- 4360035
TI  - Cryosurgery for recurrent cancer of the head and neck.

PMID- 4360036
TI  - The sensitivity to 5-hydroxytryptamine of various parts of the gastro-intestinal
      tract of the rats with experimental gastric ulcers.

PMID- 4360037
TI  - Respiratory symptoms and rash in mumps.

PMID- 4360039
TI  - Experimental silicosis. The relation between dose of quartz, length of action for
      the dust, tissue reaction and disturbance of the lung function.

PMID- 4360038
TI  - [Lipid peroxides as possible sources of free radicals capable of initiating free
      radical reactions].

PMID- 4360040
TI  - [Articular forms of sarcoidosis].

PMID- 4360041
TI  - [Contribution of rectal cytology to the endoscopic diagnosis of recto-sigmoid
      cancers. Apropos of 500 cases].

PMID- 4360042
TI  - [Treatment of Crohn's disease with BCG using Geffroy's method. Apropos of 8
      cases].

PMID- 4360043
TI  - [Skin manifestations of Hodgkin's disease. Apropos of a study of 94 patients with
      this disease].

PMID- 4360044
TI  - [Peritoneal echinococcosis. 4 cases].

PMID- 4360045
TI  - [Are acute childhood leukemia and Burkitt's sarcoma only rare complications of
      inevitable infections which generally pass unnoticed?].

PMID- 4360046
TI  - Aromatization of the A-ring of norethynodrel, a steroidal oral contraceptive,
      during trimethylsilylation.

PMID- 4360047
TI  - Renal hypertension in children.

PMID- 4360048
TI  - [Discriminantal method of diagnosing with increased accuracy].

PMID- 4360049
TI  - [Neurological aspects of neuro-oncology].

PMID- 4360050
TI  - Effects of isoflurane and halothane on contractility and the cyclic 3', 5'
      adenosine monophosphate system in the rat aorta.

PMID- 4360051
TI  - Pregnancy in a patient with hormone deficiency.

PMID- 4360052
TI  - Capacitance, area, and thickness variations in thin lipid films.

PMID- 4360053
TI  - Proceedings: Correlations between certain biochemical properties of breast cancer
      and response to therapy: a preliminary report.

PMID- 4360054
TI  - Proceedings: Primary oropharyngeal cancer and hypercalcemia.

PMID- 4360055
TI  - Proceedings: Treatment of minimal breast cancer.

PMID- 4360056
TI  - Proceedings: Immunotherapy of malignant disease: the use of viable sensitized
      lymphocytes or transfer factor prepared from sensitized lymphocytes.

PMID- 4360057
TI  - Proceedings: Primary liver cancer. A review of the clinical features, blood
      groups, serum enzymes, therapy, and survival of 65 cases.

PMID- 4360058
TI  - [New developments in arteriosclerosis-research. Proceedings of the 3rd
      International Symposium on Arterosclerosis October 24, 28, 1973 in Berlin].

PMID- 4360059
TI  - [Incidence of hemagglutination-inhibiting antibodies against Myxovirus
      parainfluenzae-3 in the blood of persons in the city of Naples].

PMID- 4360060
TI  - [Studies of the hemagglutinating spectrum of Myxovirus influenzae (human, equine,
      swine and avian strains)].

PMID- 4360061
TI  - [Influenza in horses caused by Myxovirus influenzae, type A2. Characteristics of
      6 strains isolated at Andria in the province of Bari].

PMID- 4360062
TI  - [Isolation of herpesvirus hominis, type 2, in a case of cytologically diagnosed
      herpetic cervicitis].

PMID- 4360064
TI  - Continuing surveillance of families for studying the epidemiology of viral
      infections.

PMID- 4360065
TI  - Survey of recent literature on the menstrual cycle and behavior.

PMID- 4360063
TI  - The pathogenesis of cholera and some wider implications.

PMID- 4360066
TI  - Ultrastructural studies of eight cases of fetal Tay-Sachs disease.

PMID- 4360067
TI  - The type II epithelial cell of the lung. I. Method of isolation.

PMID- 4360069
TI  - Angiotensin I as a dipsogen: efficacy in brain independent of conversion to
      angiotensin II.

PMID- 4360068
TI  - Enzymatic solubilization and separation of glomerular collagen and sialoprotein.
      Effect of contaminating enzymes present in commercial collagenase preparations.

PMID- 4360070
TI  - [Basic data on calcium metabolism].

PMID- 4360071
TI  - Erythrocyte enzymes and glycolytic intermediates of high- and low-glutathione
      sheep.

PMID- 4360073
TI  - [Clinical case. Cutaneous amebiasis (study of 2 cases)].

PMID- 4360072
TI  - [Neutralizing antibodies against herpes simplex virus in mental patients].

PMID- 4360074
TI  - Effect of naftidrofuryl upon energy metabolism of the brain.

PMID- 4360075
TI  - Dehydration of macromolecules. II. Protective effects of certain anions on
      ribulosediphosphate carboxylase subjected to low water potenials in vitro.

PMID- 4360076
TI  - On the binding and specificity of 3,6-bis-(acetatomercurimethyl)-dioxane to DNAs
      of different base composition.

PMID- 4360077
TI  - Biological implications of the instability of the N-glycosidic bone of 3
      methyldeoxyadenosine in DNA.

PMID- 4360078
TI  - Comparison of the acceptance activity of the ribosome-bound and the total
      cellular transfer ribonucleic acids from SV40-transformed mouse fibroblasts.

PMID- 4360079
TI  - [Antibodies to myocardial tissue during xenogeneic aortic vlave transplantation].

PMID- 4360080
TI  - Succinate dehydrogenase and cytochrome C oxidase activity of antigen stimulated
      macrophages.

PMID- 4360082
TI  - Receptor mechanism concepts.

PMID- 4360081
TI  - The effect of N6-2'-O dibutyryl 3',5' cyclic adenosine monophosphate, imidazole
      and aminophylline on ganglionic transmission in the superior cervical ganglion of
      the cat.
AB  - 1. Dibutyryl cyclic AMP, injected towards the superior cervical ganglion of the
      cat, produced no consistent responses.2. Imidazole, injected towards the
      ganglion, regularly produced facilitation, both during intermittent and
      continuous preganglionic stimulation. This effect was dose-dependent and lasted 2
      10 minutes.3. Aminophylline, injected towards the ganglion, regularly produced
      depression of ganglionic transmission, both during intermittent and continuous
      preganglionic stimulation. This effect was also dose-dependent and lasted 1-4
      minutes. Papaverine produced the same type of response as aminophylline.4.
      Imidazole potentiated the ganglionic response to 1,1-dimethyl-4
      phenylpiperazinium iodide (DMPP), while aminophylline depressed it.5. The results
      of the present experiments are consistent with the view that cyclic AMP may have
      a mediating role in the process of ganglionic transmission.

PMID- 4360083
TI  - Antibiotics.

PMID- 4360084
TI  - Vasopressors in obstetrics.

PMID- 4360085
TI  - Rapid gas chromatographic assay for dehydroepiandrosterone in urine.

PMID- 4360086
TI  - A program for assessing the effect of treatment on growth and development in
      children with growth disorders.

PMID- 4360087
TI  - Chromatin, and gene regulation in eukaryotic cells at the transcriptional level.

PMID- 4360089
TI  - [Supervision following treatment of gonorrhea].

PMID- 4360088
TI  - [Effect of Polymyxin B in selective culture media of Neisseria Gonorrhoeae].

PMID- 4360090
TI  - [Is the post-therapeutic provocation test in gonorrhea justified?].

PMID- 4360092
TI  - Nuclear cytochemical changes in rat adrenal glands stimulated by
      adrenocorticotrophic hormone.

PMID- 4360091
TI  - Surface biochemical changes accompanying primary infection with Rous sarcoma
      virus. I. Electrokinetic properties of cells and cell surface
      glycoprotein:glycosyl transferase activities.

PMID- 4360093
TI  - Periodate-induced lymphocyte transformation. 3. Effects of temperature and pH.

PMID- 4360094
TI  - Surface biochemical changes accompanying primary infection with Rous sarcoma
      virus. II. Proteolytic and glycosidase activity and sublethal autolysis.

PMID- 4360095
TI  - Reactivation of chick erythrocyte nuclei in heterokaryons with rat hepatoma
      cells.

PMID- 4360096
TI  - The relationship between cell growth, macromolecular synthesis and poly ADP
      ribose polymerase in lymphoid cells.

PMID- 4360097
TI  - Heavy metals and spermatozoan motility. II. Turbidity changes induced by divalent
      cations and adenosinetriphosphate in sea urchin sperm flagella.

PMID- 4360098
TI  - Dipyrone as a cause of drug rashes: an epidemiologic study.

PMID- 4360099
TI  - Cytochrome oxidase activity of mitochondria in sensory nerve endings of mouse
      palatal rugae.

PMID- 4360100
TI  - Clinical pathological conference. The man without history.

PMID- 4360101
TI  - Different binding of RNA polymerase to individual promoters.

PMID- 4360102
TI  - Mutants of Escherichia coli unable to metabolize cytidine: isolation and
      characterization.

PMID- 4360103
TI  - [Electrical reactions of cat parietal cortex association neurons to stimulation
      of the reticular and anterior ventral nuclei of the thalamus].

PMID- 4360104
TI  - [Responses of the somatosensory cortex neurons of awake cats to stimulation of
      the ventro-postero-lateral nucleus of the thalamus].

PMID- 4360105
TI  - [The role of cyclic adenosine-3',5'-monophosphate in olfactory reception].

PMID- 4360106
TI  - [The electrical properties of the subsynaptic and non-synaptic membranes of the
      horizontal cells of the turtle retina].

PMID- 4360107
TI  - Melanotic neuroectodermal tumor of infancy. A case report and review.

PMID- 4360108
TI  - Protocollagen proline hydroxylase activity in human dental pulp at various stages
      of development.

PMID- 4360109
TI  - Peripheral vascular actions of alpha-methyl-DOPA and its mode of action on
      arterioles.

PMID- 4360110
TI  - Isolated adrenal cortex cells: ACTH4-23 (NH2), ACTH5-24, ACTH6-24 and ACTH7-23
      (NH2); cyclic AMP and corticosterone production.

PMID- 4360111
TI  - Endotoxin-induced alterations in isolated fat cells: effect on norepinephrine
      stimulated lipolysis and cyclic 3',5'-adenosine monophosphate accumulation.

PMID- 4360112
TI  - Characterization of gluconeogenesis in enzymatically isolated parenchymal cells
      of rat liver.

PMID- 4360113
TI  - The everted rat intestine used as a model system to demonstrate regulation of
      sodium absorption following hemorrhage.

PMID- 4360114
TI  - Calcium-secretagogue interaction in the stimulation of gastric acid secretion.

PMID- 4360115
TI  - Radiation-enhanced survival of a human virus in normal and malignant rat cells.

PMID- 4360116
TI  - Correlation of C-type virus (WF-1) production and heme synthesis in a rat
      fibroblastic cell line.

PMID- 4360117
TI  - Effect of glucosamine administration in normal rats in comparison with
      streptozotocin treatment.

PMID- 4360118
TI  - Regulation of gingival collagenase: a possible role for a mast cell factor.

PMID- 4360119
TI  - The effect of cold on the composition of the phospholipids of the blood plasma of
      healthy athletes.

PMID- 4360120
TI  - Functions of the mammalian cerebral cortex in movement.

PMID- 4360121
TI  - Studies on the neural control of the skating reflex, and the origin of its
      variations in field population of the hemipterous insect Gerris.

PMID- 4360122
TI  - Heterogeneity of enzymes in leukaemic eosinophils.

PMID- 4360123
TI  - [Should we try to prevent epidemic hepatitis at present?].

PMID- 4360124
TI  - [Need for a definite mass of fat. Its measurement, mechanisms, and implications
      for treatment].

PMID- 4360125
TI  - [Paraneoplastic endocrine syndromes. 2].

PMID- 4360126
TI  - [Cold thoracic abscess due to Histoplasma duboisii. Treatment using rifampicin].

PMID- 4360127
TI  - Interactions of the pharmacological receptors of blood platelets with adenylate
      cyclase.

PMID- 4360128
TI  - Cyclic adenosine 3',5'-monophosphate dependent protein kinase of human platelets:
      membrane phosphorylation and regulation of platelet function.

PMID- 4360129
TI  - The release reaction: is it a common mechanism in all types of hemostatic cells?

PMID- 4360130
TI  - Neonatal familial type II hyperlipoproteinemia: cord blood cholesterol and follow
      up study in 1.323 births.

PMID- 4360131
TI  - Long term follow-up of the paced patients.

PMID- 4360132
TI  - Bilateral Wilms' tumor. Treatment, management, and review of the literature.

PMID- 4360133
TI  - Obstructive uropathy secondary to calcified metastatic adenocarcinoma of colon.

PMID- 4360134
TI  - [Biochemical aspects of human behavior].

PMID- 4360135
TI  - [The development of the carpal skeleton in children with juvenile osteochondrosis
      and slipping epiphysis of the neck of femur (author's transl)].

PMID- 4360136
TI  - [Factors influencing brain volume].

PMID- 4360137
TI  - [The ultrastructural and biochemical characteristics of different components of
      the visual analyzer under conditions of prolonged deprivation].

PMID- 4360139
TI  - Immunofluorescence measurement of C1 inactivator (alpha 2 neuraminoglycoprotein)
      activity of the surface of human carcinoma cells.

PMID- 4360140
TI  - Stability of human leukocyte interferon towards heat.

PMID- 4360138
TI  - A micro assay for mouse and human interferon. II. Dose-response in different in
      cell-virus systems.

PMID- 4360141
TI  - Diagnostic scoring system for mammary carcinoma.

PMID- 4360142
TI  - Lymphoid cells in carcinoma of the breast. Failure of response to
      phytohaemagglutinin in vitro.

PMID- 4360143
TI  - Amyotrophic lateral sclerosis. Electrophysiologic study (number of motor units
      and rate of decay of motor units).

PMID- 4360145
TI  - Hereditary brachial neuropathy. Report of two families.

PMID- 4360144
TI  - Multiple muscle analysis of motor units in muscular dystrophy.

PMID- 4360146
TI  - Folate deficiency and neurological disease. One case with a close association.

PMID- 4360147
TI  - Interspecies infection by feline leukemia virus: serial cell-free transmission in
      dogs of malignant lymphomas induced by feline leukemia virus.

PMID- 4360148
TI  - Burkitt's lymphoma: cell kinetics, treatment and immunology.

PMID- 4360149
TI  - Viral envelope antigens of the viruses of feline leukemia-sarcoma complex.

PMID- 4360150
TI  - Significance of leukemia in animals for the human disease.

PMID- 4360151
TI  - Structural and serological studies on animal 'C-type particles' and their
      implications for demonstrating corresponding viruses in man.

PMID- 4360152
TI  - Studies on the relationship of RNA viruses to the origin of leukemia and solid
      tumors of animals and man.

PMID- 4360153
TI  - Electron microscopy of feline leukaemia virus RNA.

PMID- 4360154
TI  - Electron microscopy of early interactions between feline leukaemia virus and
      cells in tissue culture.

PMID- 4360155
TI  - Role of C-type virus in bovine lymphosarcoma.

PMID- 4360156
TI  - A comparative study in vitro of a simian virus isolated from spontaneous woolly
      monkey fibrosarcoma and of a known feline fibrosarcoma virus.

PMID- 4360157
TI  - Continuing studies of feline sarcoma virus-induced tumors in nonhuman primates.

PMID- 4360158
TI  - Biological studies in four species of nonhuman primates with simian sarcoma virus
      (Lagothrix).

PMID- 4360159
TI  - Simian sarcoma virus: oncogenicity, focus assay, presence of associated virus,
      and comparison with avian and feline sarcoma virus-induced neoplasia in marmoset
      monkeys.

PMID- 4360160
TI  - The epidemiologic and genetic aspects of an outbreak of leukemia among Hamadryas
      baboons of the Sukhumi monkey colony.

PMID- 4360161
TI  - Structural components of a murine leukemia virus and the plasma membrane of virus
      infected cells.

PMID- 4360162
TI  - High resolution electron microscopy studies of murine leukemia viruses.

PMID- 4360163
TI  - An analysis of antigens on the surface of murine leukemia viruses and cells.

PMID- 4360164
TI  - Etiological strain specificities of the avian tumor viruses.

PMID- 4360165
TI  - Studies of interferon and murine leukemia sarcoma virus group.

PMID- 4360166
TI  - Transmission and expression of the leukemia introducing agent in BALB-cf(R3)
      mice.

PMID- 4360167
TI  - Demonstration of helper activity with human leukemic tissue extracts.

PMID- 4360168
TI  - Immunizing and interfering action of non-leukemogenic C-type murine virus
      variants in leukemogenesis.

PMID- 4360169
TI  - Spleen focus assays with a mouse leukemia virus in mice treated with actinomycin
      D, L-asparaginase or rifampicin.

PMID- 4360170
TI  - Effects of STAS JLSV5 and silicotungstate on the replication of murine sarcoma
      virus (Moloney) and poliovirus.

PMID- 4360171
TI  - In vitro transformation of leukocytes with a guinea pig herpes-like virus.

PMID- 4360172
TI  - Studies on oncogenic properties of Epstein-Barr virus.

PMID- 4360173
TI  - Persistence of Epstein-Barr virus DNA in human tumor cells.

PMID- 4360174
TI  - The possible significance of morphological transformation of human fibroblasts by
      EB virus in vitro.

PMID- 4360175
TI  - A prospective sero-epidemiological study to investigate the role of EBV in
      Burkitt's lymphoma.

PMID- 4360176
TI  - Purification of Herpesvirus saimiri DNA.

PMID- 4360177
TI  - Studies on the interrelationship of type B and type C virus particles in breast
      cancer and in leukemia.

PMID- 4360178
TI  - The 60-70S RNA of avian sarcoma and leukosis viruses--distribution of class a and
      b subunits.

PMID- 4360179
TI  - Minor base changes in transfer ribonucleic acid in avian myeloblastosis virus.

PMID- 4360180
TI  - Presence of avian leukosis virus genes, in DNA form in normal chickens.

PMID- 4360181
TI  - A comparative study of Marek's disease virus proteins.

PMID- 4360182
TI  - Chromosomes of viral-transformed BALB-c-3T3 cells.

PMID- 4360183
TI  - Chemical co-carcinogenesis: differential action of various compounds,
      derepression of endogenous C-type RNA genomes, and influence of different
      genotypes of mice.

PMID- 4360184
TI  - RNA tumor virus antigen expression in chemically-induced tumors. Significance of
      specific chemical carcinogens to the derepression of the C-type RNA virogene and
      oncogene expressions.

PMID- 4360185
TI  - Possible activation of C-type particles during 'progression' of the chemically
      induced pulmonary tumors in mice.

PMID- 4360186
TI  - RNA tumor virus genomes as determinants of chemically-induced transformation in
      vitro.

PMID- 4360187
TI  - Isolation and characterization of the hamster C-type viruses.

PMID- 4360188
TI  - In vitro carcinogenesis studies: dual effect of RNA tumor viruses and
      carcinogenic chemicals or DNA viruses.

PMID- 4360189
TI  - Influence of immune suppression on the induction of neoplasms by MLV and MSV.

PMID- 4360190
TI  - The role of immunity in radiation leukemogenesis.

PMID- 4360191
TI  - Homologous and heterologous immunization against Rous sarcoma.

PMID- 4360192
TI  - Isolation and characterization of the A-type of latent hamster virus.

PMID- 4360194
TI  - Relationship between humoral antibodies and the failure to develop progressive
      tumors in cats injected with feline sarcoma virus (FSV).

PMID- 4360193
TI  - Antibodies in chickens against avian leukosis virus group specific antigen.

PMID- 4360196
TI  - Antibodies to Epstein-Barr virus associated antigens in Burkitt's lymphoma.

PMID- 4360195
TI  - Detection of the feline leukemia virus and other mammalian oncornaviruses by
      immunofluorescence.

PMID- 4360197
TI  - Studies of human cells infected by leukemia viruses.

PMID- 4360198
TI  - EBV antibody in monkeys and apes.

PMID- 4360200
TI  - Feline leukaemia virus infection--the spectrum of associated disease and its
      relevance to the pathogenesis and immunology of leukaemia.

PMID- 4360199
TI  - Avian virus-induced leukemia-a model of cell differentiation.

PMID- 4360201
TI  - Cell kinetics of virally-induced leukemias.

PMID- 4360203
TI  - Interaction of Sendai virus and rabbit sperm: transmission and scanning electron
      microscopy.

PMID- 4360202
TI  - Guanine metabolism in preimplantation mouse embryo.

PMID- 4360205
TI  - [Nature of multinuclear elements in giant cell bone neoplasms].

PMID- 4360204
TI  - Hormonal effects of estrogen-protein conjugates on rat uterus.

PMID- 4360206
TI  - [Circulation of respiratory viruses in a children's community].

PMID- 4360207
TI  - [Histochemical studies of glucide metabolism in the liver of rabbits treated with
      endotoxin].

PMID- 4360208
TI  - [Nonspecific phosphomonoesterases in saliva and gingival tissues as well as serum
      inorganic phosphate and calcium levels in periodontal diseases].

PMID- 4360209
TI  - [The labial kidneys of Cylindroiulus teutonicus Pocock (londinensis, C. L. K.)
      (Diplopoda, Iuloidea): histological and ultrastructural study].

PMID- 4360210
TI  - [Solubilization of aortic membrane receptors of angiotensin II].

PMID- 4360211
TI  - Therapy strategies, personality orientation and recovery from alcoholism.

PMID- 4360212
TI  - [Amino acids loading in patients with familial amyloidotic polyneuropathy].

PMID- 4360213
TI  - Family planning: hospitals should expand services.

PMID- 4360214
TI  - Storage and activity of prostaglandin-like substance in body tissues of rats fed
      high fat diets.

PMID- 4360215
TI  - Bone case of the month.

PMID- 4360216
TI  - Distribution of women physicians, 1971.

PMID- 4360217
TI  - Thin fat people.

PMID- 4360218
TI  - Do oral contraceptives need to be interrupted in order to treat vaginal
      candidiasis?

PMID- 4360219
TI  - Improved Gram's stain for buffy coat smears.

PMID- 4360220
TI  - Levels of nicotinamide adenine dinucleotide and reduced nicotinamide adenine
      dinucleotide in facultative bacteria and the effect of oxygen.
AB  - Nicotinamide adenine dinucleotide (NAD) and reduced NAD (NADH) levels have been
      measured in bacterial cultures. The cofactors were assayed by using the very
      sensitive cycling assay described previously by Cartier. Control experiments
      showed that the level of total NAD(H) falls during harvesting, and so samples
      were taken quickly from growing cultures and extracted immediately without
      separating the cells from the medium. Total NAD(H) ranged from 4.0 to 11.7
      mumoles/g of dry cells for three facultative organisms, Klebsiella aerogenes,
      Escherichia coli, and Staphylococcus albus. NADH was remarkably constant in these
      bacteria; only one out of ten series of determinations was outside the range 1.4
      to 1.9 mumoles/g of dry cells. NAD(+) showed much greater variation. An anaerobe
      (Clostridium welchii) had significantly more total NAD(H) whereas an aerobe
      Pseudomonas aeruginosa had about as much NAD(H) as the facultative organisms. NAD
      and NADH were measured during growth: once more NADH was much more constant than
      NAD. During change-over between aerobiosis and anaerobiosis, NADH showed a
      temporary increase but then returned to a constant level, whereas NAD changed
      from high aerobically to low anaerobically. These results are discussed in terms
      of the control mechanisms that may be involved.

PMID- 4360221
TI  - Regulation of myo-inositol catabolism in Aerobacter aerogenes.
AB  - A mutant of Aerobacter aerogenes produces constitutively the series of enzymes
      that mediates the degradation of myo-inositol and which in the wildtype strain is
      inducible. When grown on l-histidine, the mutant forms the enzymes at a level
      approximately three times as high as that seen in the induced wild type. The
      enzymes appear to be coordinately regulated and are sensitive to catabolite
      repression. Unless repressed, the synthesis of these enzymes markedly retards the
      growth of the mutant.

PMID- 4360222
TI  - Kinetic properties of phosphotransacetylase from Veillonella alcalescens.
AB  - The phosphotransacetylase of Veillonella alcalescens catalyzes a reversible
      reaction with Michaelis-Menten kinetics for all substrates. The rate of the
      reverse reaction (the synthesis of acetyl coenzyme A from acetyl phosphate) was
      6.5 times greater than the rate of the forward reaction (the synthesis of acetyl
      phosphate from acetyl coenzyme A). The apparent K(m) values determined for the
      forward reaction were 8.6 x 10(-6)m for acetyl coenzyme A and 9.3 x 10(-3)m for
      phosphate. In the reverse reaction, the K(m) values were 3.3 x 10(-4)m for
      coenzyme A and 5.9 x 10(-4)m for acetyl phosphate. The results of an analysis of
      the inhibition by end products in the forward and reverse directions were
      compatible with a random bi- bi- mechanism. The enzyme was inhibited by adenosine
      triphosphate and adenosine diphosphate but was not affected by reduced
      nicotinamide adenine dinucleotide or pyruvate. The inhibition by adenosine
      triphosphate was noncompetitive with respect to acetyl phosphate and competitive
      with respect to coenzyme A. MgCl(2) reversed the inhibition by adenosine
      triphosphate or adenosine diphosphate. The role of Mg(2+) and adenylates in the
      regulation of phosphotranscetylase activity is discussed.

PMID- 4360223
TI  - De novo biosynthesis of nicotinamide adenine dinucleotide in Escherichia coli:
      excretion of quinolinic acid by mutants lacking quinolinate phosphoribosyl
      transferase.
AB  - The excretion of quinolinic acid was studied in growing and resting cells of
      Escherichia coli K-12 nadC(13). Under optimal conditions, this organism could
      synthesize quinolinic acid in several-fold excess of the amount which would be
      required for normal growth. The excretion of quinolinic acid was controlled by
      the concentration of nicotinamide adenine dinucleotide (NAD) precursors available
      to the organism either during growth or during incubation in dense cell
      suspensions. These observations suggest that biosynthesis of NAD de novo is
      regulated by both repression and feedback inhibition. Analogues of niacin which
      inhibit bacterial growth also inhibited and repressed the synthesis (excretion)
      of quinolinic acid. The pH optimum for quinolinic acid excretion agreed favorably
      with the optimum observed for its synthesis in vitro. The rate of quinolinic acid
      excretion was strongly influenced by the concentration of ribose or glycerol in
      the medium.

PMID- 4360224
TI  - The pathogenicity of Entamoeba histolytica: is heat stress a factor?

PMID- 4360225
TI  - [Clinical features, diagnosis and treatment of alveolar cell carcinoma (report on
      21 cases) (author's transl)].

PMID- 4360226
TI  - The nature of the establishment barrier for Trypanosoma brucei in the gut of
      Glossina pallidipes.

PMID- 4360227
TI  - Letter: Assay of serum enzymes in trypanosomal infection: interference by
      pyruvate.

PMID- 4360228
TI  - [Catecholamine excretion in tumors of the cerebral hemispheres in the pre- and
      postoperative periods].

PMID- 4360229
TI  - [Clinical use of spot cerebral macroangiography].

PMID- 4360231
TI  - [Incidence of Entamoeba histolytica infections in people returning from tropical
      countries].

PMID- 4360232
TI  - [Methods in microscopic diagnosis of Entamoeba histolytica].

PMID- 4360230
TI  - [Stereotaxic cryodestruction of hypophyseal tumors].

PMID- 4360233
TI  - [Pathogenic organisms of infectious heart diseases].

PMID- 4360235
TI  - The effects of nucleotides on the alpha-glucosidase formation in baker's yeast
      protoplasts.

PMID- 4360234
TI  - The use of isocyanides for the immobilization of biological molecules.

PMID- 4360237
TI  - [Control of poliomyelitis. I. Retrospective view and current situation in the
      world with special reference to our country].

PMID- 4360236
TI  - [Determination of sialic acid in some hamster tumors induced by adenoviruses,
      para-adenovirus hybrids and papovavirus SV 40].

PMID- 4360238
TI  - [Stage of immunity to Poliovirus type 1 and 3 in adult women and in newborn
      infants: study of comparative efficiency of 2 methods for determination of
      neutralizing antibodies].

PMID- 4360239
TI  - [Experience with the storage over years of actinomycetes on agarizied nutrient
      media and in quartz sand].

PMID- 4360240
TI  - [Graphic analytical evaluation of the effectiveness of methods for the
      quantitative determination of the combined action of antibiotics].

PMID- 4360241
TI  - Control of in vivo luminescence in psychrophilic marine Photobacterium.

PMID- 4360242
TI  - On the passage-restricting role of acid mucopolysaccharides in the endothelium of
      pig aortas.

PMID- 4360243
TI  - Preparation of tissue fluid of the vessel wall and determination of its
      lipoproteins.

PMID- 4360244
TI  - Effects of oxandrolone on plasma lipoproteins and the intravenous fat tolerance
      in man.

PMID- 4360245
TI  - Letter: IIB or not IIB? Classification of hyperlipoproteinaemias.

PMID- 4360246
TI  - Affinity chromatography of nicotinamide-adenine dinucleotide-linked
      dehydrogenases on immobilized derivatives of the dinucleotide.
AB  - 1. Three established methods for immobilization of ligands through primary amino
      groups promoted little or no attachment of NAD(+) through the 6-amino group of
      the adenine residue. Two of these methods (coupling to CNBr-activated agarose and
      to carbodi-imide-activated carboxylated agarose derivatives) resulted instead in
      attachment predominantly through the ribosyl residues. Other immobilized
      derivatives were prepared by azolinkage of NAD(+) (probably through the 8
      position of the adenine residue) to a number of different spacer-arm-agarose
      derivatives. 2. The effectiveness of these derivatives in the affinity
      chromatography of a variety of NAD-linked dehydrogenases was investigated,
      applying rigorous criteria to distinguish general or non-specific adsorption
      effects from truly NAD-specific affinity (bio-affinity). The ribosyl-attached
      NAD(+) derivatives displayed negligible bio-affinity for any of the NAD-linked
      dehydrogenases tested. The most effective azo-linked derivative displayed strong
      bio-affinity for glycer-aldehyde 3-phosphate dehydrogenase, weaker bio-affinity
      for lactate dehydrogenase and none at all for malate dehydrogenase, although
      these three enzymes have very similar affinities for soluble NAD(+). Alcohol
      dehydrogenase and xanthine dehydrogenase were subject to such strong non-specific
      interactions with the hydrocarbon spacer-arm assembly that any specific affinity
      was completely eclipsed. 3. It is concluded that, in practice, the general
      effectiveness of a general ligand may be considerably distorted and attenuated by
      the nature of the immobilization linkage. However, this attenuation can result in
      an increase in specific effectiveness, allowing dehydrogenases to be separated
      from one another in a manner unlikely to be feasible if the general effectiveness
      of the ligand remained intact. 4. The bio-affinity of the various derivatives for
      lactate dehydrogenase is correlated with the known structure of the NAD(+)
      binding site of this enzyme. Problems associated with the use of immobilized
      derivatives for enzyme binding and mechanistic studies are briefly discussed.

PMID- 4360247
TI  - A comparison of the physical and chemical properties of four cytochromes c from
      Azotobacter vinelandii.
AB  - 1. A modified method for the separation and purification of four cytochromes c
      from Azotobacter vinelandii is described. Two new cytochromes c have been
      purified and are designated cytochromes c(551) and c(555). 2. Additional evidence
      is presented to establish the dihaem nature of cytochrome c(4).
      Ultracentrifugation data indicated similar molecular weights for the native and
      the denatured protein. Cleavage with CNBr yielded seven peptides; the amino acid
      compositions of the purified peptides were determined. Only one haem peptide was
      recovered. 3. Cytochromes c(551) and c(555) were characterized as acidic proteins
      of molecular weights about 12000. The spectral properties, isoelectric points,
      ;maps' of peptides from CNBr cleavage and amino acid compositions were determined
      for these two proteins. 4. The spectral properties, isoelectric points, molecular
      weights, CNBr peptide ;maps', amino acid compositions, relative oxidation
      reduction potentials and e.p.r. (electron-paramagnetic-resonance) spectra of the
      four cytochromes c were compared. Cytochrome c(4) and cytochrome c(551) appear to
      be distinct proteins. The distinction between cytochromes c(5) and c(555) was not
      as clear, and our data are inadequate to establish firmly that they are distinct
      proteins. 5. The dihaem nature of cytochrome c(4) is evident in its e.p.r.
      spectrum. The e.p.r. spectra are similar to the spectra of mammalian cytochromes
      c.

PMID- 4360248
TI  - Kinetic studies of the acylation of pig muscle D-glyceraldehyde 3-phosphate
      dehydrogenase by 1,3-diphosphoglycerate and of proton uptake and release in the
      overall enzyme mechanism.
AB  - In the presence of NAD(+) the acylation by 1,3-diphosphoglycerate of the four
      active sites of pig muscle d-glyceraldehyde 3-phosphate dehydrogenase can be
      monitored at 365nm by the disappearance of the absorption band present in the
      binary complex of NAD(+) and the enzyme. A non-specific salt effect decreased the
      acylation rate 25-fold when the ionic strength was increased from 0.10 to 1.0.
      This caused acylation to be the rate-limiting process in the enzyme-catalysed
      reductive dephosphorylation of 1,3-diphosphoglycerate at high ionic strength at
      pH8. The salt effect permitted investigation of the acylation over a wide range
      of conditions. Variation of pH from 5.4 to 8.6 produced at most a two-fold change
      in the acylation rate. One proton was taken up per site acylated at pH8.0. By
      using a chromophoric H(+) indicator the rate of proton uptake could be monitored
      during the acylation and was also almost invariant in the pH range 5.5-8.5.
      Transient kinetic studies of the overall enzyme-catalysed reaction indicated that
      acylation was the process involving proton uptake at pH8.0. The enzyme mechanism
      is discussed in the light of these results.

PMID- 4360249
TI  - The amino acid sequence of cytochrome c' from Alcaligenes sp. N.C.I.B. 11015.
AB  - The amino acid sequence of the cytochrome c' from Alcaligenes sp. N.C.I.B. 11015
      (Iwasaki's ;Pseudomonas denitrificans') has been determined. This organism is the
      only non-photosynthetic bacterium in which the protein has been found. The
      protein consists of a single polypeptide chain of 127 residues, with a single
      haem covalently attached to two cysteines. Unlike normal cytochromes c, the haem
      attachment site is very close to the C-terminus. The amino acid sequence around
      the haem attachment site is very similar to that of Chromatium vinosum D
      cytochrome c'. Detailed evidence for the amino acid sequence of the protein has
      been deposited as Supplementary Publication SUP 50022 at the British Library
      (Lending Division), (formerly the National Lending Library for Science and
      Technology), Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies may be obtained
      on the terms given in Biochem. J. (1973) 131, 5.

PMID- 4360250
TI  - Purification and properties of a mouse liver plasma-membrane glycoprotein
      hydrolysing nucleotide pyrophosphate and phosphodiester bonds.
AB  - 1. A mouse liver plasma-membrane preparation was solubilized in an N
      dodecylsarcosinate-Tris buffer, pH7.8, and the proteins and glycoproteins were
      separated by a rate-zonal centrifugation in sucrose-detergent gradients. 2. A
      peak of alkaline phosphodiesterase activity which sedimented ahead of the 5'
      nucleotidase peak was associated with a major glycoprotein component of the
      plasma membrane. 3. The phosphodiesterase activity was then purified further by
      gel filtration and gave a single glycoprotein band after electrophoresis on
      polyacrylamide gels. The apparent molecular weight of the polypeptide at pH7.4
      and 8.9 was 128000-130000 and was independent of the polyacrylamide
      concentration. Electrophoresis in gels containing deoxycholate showed that the
      protein band was coincident with phosphodiesterase activity. 4. After two
      dimensional immunoelectrophoresis, with agarose containing rabbit anti-(mouse
      plasma-membrane) antiserum as second dimension, the enzyme showed one component
      which was also coincident with the phosphodiesterase activity. 5. An amino acid
      composition of the glycoprotein is presented. Carbohydrate analysis indicated the
      presence of glucosamine, neutral sugars and sialic acid. 6. The enzyme was also a
      nucleotide pyrophosphatase, as shown by a similar enrichment during purification
      of activity towards ATP, NAD(+), UDP-galactose and UDP-N-acetylglucosamine. The
      phosphodiesterase activity, measured by using dTMP p-nitrophenyl ester as
      substrate, was competitively inhibited by nucleotide pyrophosphate substrates.
      The enzyme showed little or no activity towards RNA, cyclic AMP, AMP, ADP and
      glycerylphosphorylcholine. 7. The significance of this enzyme activity in the
      plasma membrane is discussed.

PMID- 4360251
TI  - Immunochemical characterization of proteins from mouse liver plasma membranes.
AB  - 1. Antiserum was prepared in rabbits against a purified mouse liver plasma
      membrane fraction. 2. The antiserum was made to react with an (125)I-labelled
      alkaline-EDTA extract of the plasma membranes, and the immunoprecipitate analysed
      by polyacrylamide-gel electrophoresis. Seven proteins were immunoprecipitated and
      a single glycoprotein present in the alkaline-EDTA-soluble fraction was found to
      be a major component. 3. The alkaline-EDTA-soluble fraction was analysed by two
      dimensional immunoelectrophoresis and this procedure indicated the presence of
      six antigenic components. 4. The plasma membranes were also extracted with 1%
      deoxycholate-1% Triton X-100; 50% of the protein, 80% of the alkaline
      phosphodiesterase activity and 30% of the 5'-nucleotidase activity were
      solubilized. 5. Two-dimensional immunoelectrophoresis of the deoxycholate-Triton
      X-100 extract indicated the presence of six antigens. 6. The relative
      distribution of the six antigens among the fractions obtained during the
      extraction procedure was examined immunoelectrophoretically to provide
      information on their disposition within the membrane.

PMID- 4360252
TI  - The b-type cytochromes of bovine heart mitochondria: absorption spectra,
      enzymatic properties, and distribution in the electron transfer complexes.

PMID- 4360253
TI  - Cytochrome c involved in the reductive decomposition of organic mercurials.
      Purification of cytochrome c-I from mercury-resistant Pseudomonas and reactivity
      of cytochromes c from various kinds of bacteria.

PMID- 4360254
TI  - [Influence of pH on the synthesis of oxidase (cytochrome a3) in Bacillus
      coagulans, a thermophilic microorganism capable of "respiratory adaptation"].

PMID- 4360255
TI  - Shifts of bacteriochlorophyll and carotenoid absorption bands linked to
      cytochrome c-555 photooxidation in Chromatium.

PMID- 4360256
TI  - Absorption changes of carotenoids and bacteriochlorophyll in energized
      chromatophores of Rhodospirillum rubrum.

PMID- 4360257
TI  - Electron paramagnetic resonance signal II in spinach chloroplasts. I. Kinetic
      analysis for untreated chloroplasts.

PMID- 4360258
TI  - Electron paramagnetic resonance signal II in spinach chloroplasts. II.
      Alternative spectral forms and inhibitor effects on kinetics of signal II in
      flashing light.

PMID- 4360259
TI  - The back reaction in the primary electron transfer couple of photosystem II of
      photosynthesis.

PMID- 4360260
TI  - C-550 in photosystem II subchloroplast particles.

PMID- 4360261
TI  - Inorganic pyrophospatase and photosynthesis by isolated chloroplasts. I.
      Characterisation of chloroplast pyrophosphatase and its relation to the response
      to exogenous pyrophosphate.

PMID- 4360262
TI  - Inorganic pyrophosphatase and photosynthesis by isolated chloroplasts. II. The
      controlling influence of orthophosphate.

PMID- 4360263
TI  - [Use of water-insoluble enzymes for determination of the nucleotide composition
      and terminal analysis of oligonucleotides].

PMID- 4360264
TI  - [Reaction of yeast inorganic pyrophosphatase with radioactive inorganic phosphate
      and pyrophosphate].

PMID- 4360265
TI  - [The effect of pentagastrin, histamine and cyclic 3',5'-AMP on rat gastric
      mucosal carbonic anhydrase activity].

PMID- 4360266
TI  - [The role of inorganic pyrophosphate in mitochondrial energy metabolism].

PMID- 4360267
TI  - [In vivo incorporation of P32-orthophosphate in individual rat adrenal
      phospholipids].

PMID- 4360268
TI  - Glia of myelination and fat deposit during early myelogenesis.

PMID- 4360269
TI  - Effects of caffeine on radiation-induced phenomena associated with cell-cycle
      traverse of mammalian cells.
AB  - Caffeine induced a state of G(1) arrest when added to an exponentially growing
      culture of Chinese hamster cells (line CHO). In addition to its effect on cell
      cycle traverse, caffeine ameliorated a number of the responses of cells to
      ionizing radiation. The duration of the division delay period following X
      irradiation of caffeine-treated cells was reduced, and the magnitude of reduction
      was dependent on caffeine concentration. Cells irradiated during the DNA
      synthetic phase in the presence of caffeine were delayed less in their exit from
      S, measured autoradiographically, and the radiation-induced reduction of
      radioactive thymidine incorporation into DNA was lessened. Cells synchronized by
      isoleucine deprivation, while being generally less sensitive to the effects of
      ionizing radiation than mitotically synchronized cells, were equally responsive
      to the effects of caffeine. The X-ray-induced reduction of phosphorylation of
      lysine-rich histone F1 was less in caffeine-treated cells than in untreated
      cells. Finally, survival after irradiation was only slightly reduced in caffeine
      treated cells. A possible role of cyclic AMP in cell-cycle traverse of irradiated
      cells is discussed.

PMID- 4360272
TI  - An extralemniscal projection to the centrum medianum and pulvinar of the
      thalamus.

PMID- 4360270
TI  - [Calcitonin: nature, secretion mechanisms, therapeutic possibilities].

PMID- 4360271
TI  - The metabolic and hemodynamic effects of prolonged bed rest in normal subjects.

PMID- 4360273
TI  - [Protein inhibitor of phosphodiesterase].

PMID- 4360274
TI  - [Respiration-associated synthesis of inorganic pyrophosphate in animal tissue
      mitochondria].

PMID- 4360275
TI  - [Study of the role of the spatial factor in synaptic mechanisms by the method of
      pharmokinetics of multichambered systems].

PMID- 4360276
TI  - Estrogen and progestogen binders in human and rat mammary carcinoma.

PMID- 4360277
TI  - Recovery of the genome of murine sarcoma virus (MSV) after infection of cells
      with nuclear DNA from MSV transformed non-virus producing cells.

PMID- 4360278
TI  - The relationship between growth rate, labelling index and histological type of
      human solid tumours.

PMID- 4360279
TI  - Postheparin plasma lipase in human subjects. Studies with chylomicrons, very-low
      density lipoproteins and a fat emulsion.

PMID- 4360280
TI  - Fine structural studies in myasthenia gravis. I. Muscle fibre lesions.

PMID- 4360281
TI  - A histochemical study of enzymes of carbohydrate metabolism in the rat
      metanephros.

PMID- 4360282
TI  - Ultrastructural changes in the rat neurohypophysis in hyper- and hypofunction of
      adrenal glands.

PMID- 4360283
TI  - Ultrastructural changes in nucleus supraopticus and paraventricularis of rat
      hypothalamus in hyper- and hypofunction of the adrenals.

PMID- 4360284
TI  - Cytochemical and ultrastructural features of simian virus 40 transformed
      macrophages.

PMID- 4360285
TI  - Ultrastructural changes of the small intestine in rats during neomycin induced
      enteropathy.

PMID- 4360286
TI  - Studies on cytoplasmic tubular inclusions in papilloma and other epithelial
      tumours.

PMID- 4360287
TI  - Ultrastructure and respiration of isolated heart cells.

PMID- 4360288
TI  - The study of iodized oil emulsions for indirect lymphography.

PMID- 4360289
TI  - Erythrocyte adenine phosphoribosyltransferase in the Lesch-Nyhan syndrome.

PMID- 4360290
TI  - Inhibition of Herpes simplex virus replication by camptothecin.

PMID- 4360291
TI  - Inhibition of Herpes simplex virus replication by cordycepin.

PMID- 4360292
TI  - The tumor-promoter phorbol ester (12-O-tetradecanoyl-phorbol-13-acetate), a
      potent aggregating agent for blood platelets.
AB  - The phorbol ester 12-0-tetradecanoyl-phorbol-13-acetate, a potent tumor-promoting
      agent, caused irreversible platelet aggregation when more than 0.02 microM was
      stirred with human citrated or heparinized platelet-rich plasma (PRP). With
      washed platelets, 1 nM was effective. The alcohol phorbol, which has little tumor
      promoting activity, failed to cause platelet aggregation. With all but low
      concentrations of phorbol ester, aggregation was succeeded by a rapid phase. The
      latter was prevented or reduced by enzymes which destroy ADP and by aspirin, was
      associated with a change in platelet shape, and was presumably due to released
      ADP. At higher concentrations, only a rapid phase was seen, and these inhibitors
      were not effective. Low concentrations did not aggregate platelets in PRP
      containing sufficient EDTA or EGTA to chelate ionized calcium or in PRP from
      thrombasthenic patients; higher concentrations caused slight aggregation. Both
      the primary, non-ADP-dependent aggregation and the rapid ADP-dependent
      aggregation were markedly inhibited by substances which increase cyclic AMP,
      metabolic inhibitors, and the sulfhydryl inhibitor N-ethylmaleimide. Phorbol
      ester reduced platelet cyclic AMP only when it had been previously elevated by
      prostaglandin E(1). 1 microM did not release beta-glucuronidase, lactic
      dehydrogenase, or inflammatory material from platelets in 4-5 min despite marked
      aggregation, but liberated all three in 30 min. The possibility is discussed that
      low phorbol ester concentrations cause primary aggregation by a direct action on
      platelet actomyosin.

PMID- 4360294
TI  - Effect of cytochalasin B and colchicine on alpha-amylase release from rat parotid
      tissue slices.

PMID- 4360293
TI  - An improved method for isolating alpha granules and mitochondria from human
      platelets.

PMID- 4360295
TI  - The effect of cytochalasin B on pigment dispersion and aggregation in perfused
      Xenopus laevis tailfin melanophores.

PMID- 4360296
TI  - Alkaline phosphatase activity and the regulation of growth in transformed
      mammalian cells.

PMID- 4360297
TI  - The localization of enzymatic activities involved in uridine nucleotides
      reactions in human erythrocytes.

PMID- 4360298
TI  - Nucleoside diphosphate kinase at the cell surface of neoplastic human cells in
      culture.

PMID- 4360300
TI  - Tumor scanning with 169Yb-citrate.

PMID- 4360301
TI  - Letter: Does perchlorate enhance brain lesion visibility?

PMID- 4360299
TI  - Permeability changes during cell fusion.

PMID- 4360303
TI  - Electron microscopic studies of plant tissue cultures infected with the aster
      yellows disease.

PMID- 4360302
TI  - Acetylcholinesterase localization in the giant nerve fiber of the squid.

PMID- 4360304
TI  - [Review of research on essential hypertension].

PMID- 4360305
TI  - [Renal hypertension].

PMID- 4360306
TI  - [Na metabolism anomaly in essential hypertension].

PMID- 4360307
TI  - [Present status of research on hypertension-inducing substances].

PMID- 4360308
TI  - [Sensitizing factor and natriuretic hormones as hypertension-inducing factors].

PMID- 4360310
TI  - [Synthetic anti-angiotensin substances].

PMID- 4360309
TI  - [Renin-angiotensin-aldosterone system in essential hypertension].

PMID- 4360311
TI  - [Purification of renin and its chemical characteristics: recent progress].

PMID- 4360312
TI  - [Angiotensin I-converting enzyme: recent findings].

PMID- 4360313
TI  - [Concentration of aldosterone in the blood and its reactions to various
      stimulations in primary aldosteronism and various other diseases].

PMID- 4360314
TI  - [The pathological anatomy of ovarian tumors].

PMID- 4360315
TI  - Swine vesicular disease.

PMID- 4360316
TI  - Organ culture of bovine teat skin and its application to the study of herpes
      mammillitis and pseudocowpox infections.

PMID- 4360318
TI  - The influence of relative humidity on the stability of foot-and-mouth disease
      virus in aerosols from milk and faecal slurry.

PMID- 4360317
TI  - The antiketogenic action of an anabolic steroid administered to ketotic cows.

PMID- 4360319
TI  - The influence of haemoglobin on the fibrinolytic enzyme system.

PMID- 4360320
TI  - The effects of antiinflammatory drugs on myeloperoxidase mediated iodination in
      human granulocytes.

PMID- 4360321
TI  - Pharmacology of pressor agents on the systemic circulation.

PMID- 4360322
TI  - The in vivo regulation of the progesterone "receptor" in guinea pig uterus:
      dependence on estrogen and progesterone.

PMID- 4360323
TI  - [Clinical picture and radiotherapy of the glomus jugulare tumors].

PMID- 4360324
TI  - [Double-stranded synthetic RNA. Interferon induction and antiviral properties].

PMID- 4360325
TI  - [Color contrast lymphography in the surgical treatment of uterine cancer].

PMID- 4360326
TI  - [Clinico-morphologic characteristics of oat cell cancer of the lungs].

PMID- 4360327
TI  - [Evaluation of biochemical reactions in the diagnosis of tumors of the abdominal
      cavity].

PMID- 4360328
TI  - [Morphologic changes in cancer of the rectum under the influence of preoperative
      radiotherapy].

PMID- 4360329
TI  - [Clinical value of sinus endoscopy (author's transl)].

PMID- 4360330
TI  - [Adaption of amoebae-Crithidia-cultures (Entamoeba histolytica) to axenic
      conditions of cultivation in TP-S-1-medium of Diamond 1968 (author's transl)].

PMID- 4360331
TI  - Ultrastructure of Blastocystis hominis.

PMID- 4360333
TI  - The effects of niamid and reserpine on the nerve endings of the pineal gland.

PMID- 4360332
TI  - [Pathophysiological and toxicological aspects of Schistosoma mansoni infection in
      Mastomys natalensis under treatment with Hycanthone].

PMID- 4360334
TI  - The lymphatic capillaries of the middle ear mucosa in the guinea pig.
      Ultrastructure and permeability.

PMID- 4360335
TI  - Persistent viral hepatitis.

PMID- 4360336
TI  - Fibrous histiocytomas of the orbit.

PMID- 4360337
TI  - Ultrastructure of the synovial membrane of lambs affected with chlamydial
      polyarthritis.

PMID- 4360338
TI  - Prevalence of antibodies to herpesvirus types 1 and 2, arteritis and infectious
      anemia viral antigens in equine serum.

PMID- 4360339
TI  - Ganglionic and adrenergic effects of 2-phenylquinoline methiodide analogues.

PMID- 4360340
TI  - Cardiovascular effects of Cassella 7657 and its interaction with adenosine, NAD
      and aminophylline in dogs.

PMID- 4360341
TI  - Pharmacological influences on carbon dioxide-induced amnesia.

PMID- 4360342
TI  - Fetal consequences of maternal viral infections in pregnancy.

PMID- 4360343
TI  - The role of hemodynamic measurements in portosystemic shunt surgery.

PMID- 4360344
TI  - Selective, near-total, irreversible inactivation of peripheral
      pseudocholinesterase and acetylcholinesterase in cats in vivo.

PMID- 4360345
TI  - Effects of pyrazole, 4-bromopyrazole and 4-methylpyrazole on mitochondrial
      function.

PMID- 4360346
TI  - Effect of actinomycin D on uptake and incorporation of thymidine and hypoxanthine
      into the acid-soluble and acid-insoluble fractions of rat hepatoma cells grown in
      culture.

PMID- 4360347
TI  - Carbon tetrachloride induced liver alterations in rats pretreated with N,N'
      diphenyl-p-phenylenediamine.

PMID- 4360348
TI  - Effects of dichlorodiphenyltrichloroethane (DDT) analogs and polychlorinated
      biphenyl (PCB) mixtures on 17beta-(3H)estradiol binding to rat uterine receptor.

PMID- 4360349
TI  - Protein iodination with solid state lactoperoxidase.

PMID- 4360350
TI  - Immunospecificity of nonhistone proteins in chromatin.

PMID- 4360351
TI  - Sequence composition of rat nuclear deoxyribonucleic acid and high molecular
      weight nuclear ribonucleic acid.

PMID- 4360352
TI  - Sequence composition of rat ascites chromosomal ribonucleic acid.

PMID- 4360353
TI  - Calcium-induced phase separations in phosphatidylserine--phosphatidylcholine
      membranes.

PMID- 4360355
TI  - Inhibition of acetoacetate decarboxylase by ketophosphonates. Structural and
      dynamic probes of the active site.

PMID- 4360354
TI  - Activity of liver alcohol dehydrogenase with various substituents on the amino
      groups.

PMID- 4360356
TI  - [The hypothalamo-adenohypophyseal-adrenal neurosecretory system under conditions
      of hyperthermia].

PMID- 4360357
TI  - [The effect of different methods of preservation on the immunogenicity and
      antigenic composition of xenogenous heart valve tissue].

PMID- 4360358
TI  - [The kinetic patterns of growth of transplantable hepatomas with different
      degrees of differentiation].

PMID- 4360359
TI  - [Distribution of protein binding carcinogen in primary liver tumors induced by
      3'methyl-4-dimethylaminoazobenzene in rats].

PMID- 4360360
TI  - [The functional state of the hypothalamo-hypophyseal-adrenal system in insulin
      hypoglycemia].

PMID- 4360361
TI  - [The significance of the dose and hypertension in realizing the renal effect of
      angiotensin].

PMID- 4360362
TI  - [Use of an artificial lipid membrane in order to obtain cells of the required
      shape].

PMID- 4360363
TI  - Lymphocytosis induced in mice by supernatant fluids of Bordetella pertussis
      cultures: a histopathological study.

PMID- 4360364
TI  - Time lapse studies on the motility of fibroblasts in tissue culture.

PMID- 4360365
TI  - Interactions of normal and neoplastic fibroblasts with the substratum.

PMID- 4360366
TI  - Dual-precipitation method for lipoprotein quantitation: improvement by membrane
      ultrafiltration of lipemic samples.

PMID- 4360367
TI  - Letter: The ill-wind in direct analysis of plasma.

PMID- 4360368
TI  - Progress report on long-term oestogen therapy.

PMID- 4360370
TI  - [Disorders in the neurotransmitter system in multiple sclerosis?].

PMID- 4360369
TI  - [Investigations into the action of xylitol on the stool flora (author's transl)].

PMID- 4360371
TI  - The effect of acute or chronic ether stress on plasma ACTH concentration in the
      rat.

PMID- 4360372
TI  - Effects of hCG, asialo-hCG and the subunits of hCG upon luteinization of monkey
      granulosa cell cultures.

PMID- 4360373
TI  - ACTH effects on aldosterone production and mitochondrial ultrastructure in
      adrenal gland cultures.

PMID- 4360374
TI  - Synergism among growth hormone, ACTH, cortisol and dexamethasone in the hormonal
      induction of diabetes in rats and the diabetogenic effect of tolbutamide.

PMID- 4360375
TI  - The metabolism of cholesterol esters in rat adrenal cell suspensions.

PMID- 4360376
TI  - Adrenal progesteerone: factors controlling its secretion.

PMID- 4360377
TI  - [Comparative enzymologic, endocrinologic and electron microscopy studies on
      ovarian function in postmenopause].

PMID- 4360378
TI  - [Experimental heart valve endocardiosis in dogs induced by ACTH and DOC].

PMID- 4360379
TI  - Effect of dibutyryl cyclic AMP injected into third ventricle on the thyroid 131-I
      iodide accumulation.

PMID- 4360380
TI  - Extra-lysosomal localization of acid phosphatase in the spinal cord of the rat.

PMID- 4360381
TI  - Evidence for GABA as the synaptic transmitter of the inhibitory vestibulo-ocular
      pathway.

PMID- 4360382
TI  - Somatotopic studies on cerebellar fastigial cells.

PMID- 4360383
TI  - Excitatory and inhibitory responses of neurones of the cerebellar fastigial
      nucleus.

PMID- 4360385
TI  - Metabolism and isoenzyme alterations in experimental hepatomas.

PMID- 4360384
TI  - The pathways responsible for excitation and inhibition of fastigial neurones.

PMID- 4360386
TI  - The suppression of AD-3B mutants by supersuppressors in Neurospora crassa.
AB  - The action of eight suppersuppressors has been tested on 76 ad-3B mutants which
      were induced by base-pair transition mutagens. Thirteen mutants were found to be
      suppressible by at least one ssu gene. Most of the suppressible mutants were
      found to belong to a class in which one would expect to find nonsense mutants
      (polar complementing or noncomplementing classes, with AT at the mutant site).
      However, suppression was observed in other classes, including those containing
      presumed missense mutants. The specificity of the suppressors and the criteria
      for molecular classification of the mutants are discussed.

PMID- 4360387
TI  - Mosaic analysis of lethal mutations in Drosophila.
AB  - The effects of various lethal mutations were studied when they were present in
      the hemizygous state as sectors in genetic mosaics (gynandromorphs) of Drosophila
      melanogaster. Sixty percent of the lethals studied can survive to adulthood in
      combination with normal tissue in mosaics, whereas the remainder cause the death
      of such mosaic animals. Some of the gynandromorph-viable lethals appeared to be
      locally active, in that they allowed the survival of only those mosaics in which
      the male tissue was present in the abdomen. The regions affected by these lethals
      were identified more precisely by analysis of the tissue distributions in the
      surviving gynandromorphs.

PMID- 4360388
TI  - Dental erosion: progress of erosion measured clinically after various fluoride
      applications.

PMID- 4360389
TI  - Hepatic cell carcinoma in a dog.

PMID- 4360390
TI  - A somatic cell approach to the genetic analysis of the laboratory mouse.

PMID- 4360391
TI  - Comparative electrophoretic studies of foot-and-mouth disease virus proteins.

PMID- 4360392
TI  - An interfering component of rabies virus which contains RNA.

PMID- 4360393
TI  - Comparative electrophoretic analysis of the virus proteins of four rhabdoviruses.

PMID- 4360394
TI  - Electron microscopy and infectivity studies of the action of dimethylsulphoxide
      on two strains of tobacco mosaic virus.

PMID- 4360395
TI  - Heterogeneity of simian virus 40 populations: virus particles containing one or
      two virus DNA molecules?

PMID- 4360396
TI  - Refractory state of cells to interferon induction.

PMID- 4360397
TI  - Alterations in the surface glycoproteins of chicken erythrocytes following
      transformation with erythroblastosis strain R virus.

PMID- 4360398
TI  - Controlled trial of combinations of hydroxocobalamin-cystine and riboflavine
      cystine, in Nigerian ataxic neuropathy.
AB  - Chronic cyanide intoxication of dietary origin and riboflavine deficiency are
      believed to be major aetiological factors in Nigerian tropical ataxic neuropathy.
      The results are presented of a double-blind controlled therapeutic trial of
      combinations of large doses of hydroxocobalamin and cystine as cyanide binding
      agents together with riboflavine or placebos in Nigerian patients suffering from
      the tropical ataxic neuropathy. No clinical benefit was demonstrable with any of
      the treatments.

PMID- 4360399
TI  - Disturbances in the voluntary recruitment order of anterior tibial motor units in
      spastic paraparesis upon fatigue.
AB  - The recruitment order of motor units in the tibialis anterior muscle upon fatigue
      of tonic voluntary contraction was studied in 20 patients with severe spastic
      paraparesis. An electromyographic technique for secure identification of single
      motor units was used. Before fatigue the recruitment order is stable and low
      frequency units are recruited before high-frequency units; this recruitment
      pattern agrees with that in normal voluntary activity. When fatigue appears,
      however, the recruitment order becomes indefinite and high-frequency units can be
      recruited before low-frequency units; this recruitment pattern agrees with that
      in normal phasic voluntary activity. Finally, all voluntary activation power
      disappears, even in the case of units which have never been active. Contraction
      ability and original recruitment order are restored upon rest but also upon tonic
      reflex support of the voluntary drive. Whether the fatigue reaction may be due to
      insufficient gamma motoneurone innervation and whether it is related to
      spasticity are discussed. The practical physiotherapeutic implications are
      reviewed.

PMID- 4360400
TI  - Motor unit estimations in small muscles of the hand.
AB  - A quantal method has been employed to determine the numbers of functioning motor
      units in small muscles of the hand. In healthy subjects below the age of 60 years
      the mean number of hypothenar motor units was 380 +/- 79 and the mean number of
      thenar units innervated by the median nerve was 340 +/- 87. In older subjects
      there was a progressive reduction in the numbers of functioning units in both
      muscle groups; in some of these subjects the population of motor units in the
      extensor digitorum brevis was also estimated for comparison. A study was also
      performed on patients diagnosed as having generalized denervating diseases or
      with lesions of peripheral nerves and cervical roots; in every instance the
      number of functioning motor units was markedly reduced.

PMID- 4360401
TI  - Hypertrophic mononeuropathy.
AB  - A case of hypertrophic mononeuropathy is described in a 19-year-old female. The
      entity is very rare as only three previous cases have been reported. The light
      and electron-microscope appearances resemble those of progressive hypertrophic
      polyneuritis.

PMID- 4360402
TI  - Mixed or immune complex cryoglobulinaemia and neuropathy.
AB  - Three patients with peripheral neuropathy and mixed or immune complex
      cryoglobulinaemia are reported. The significance of mixed cryoglobulinaemia and
      the pathogenesis of the peripheral neuropathy are discussed.

PMID- 4360406
TI  - Cross-linking of collagen. Hydrogen abstraction studies on model compounds.

PMID- 4360407
TI  - Response of Escherichia coli to ethyl methanesulfonate: influence of growth phase
      and repair ability on survival and mutagenesis.

PMID- 4360408
TI  - Chemically induced mutation of L-5178Y mouse leukemia cells from asparagine
      dependence to asparagine-independence.

PMID- 4360410
TI  - Theophylline potentiation of in vitro effects of ACTH and catecholamines in
      rabbit adipose tissue.

PMID- 4360409
TI  - Humoral transmission of sleep. 8. Effects of the "sleep factor delta" on
      cerebral, motor and visceral activities.

PMID- 4360411
TI  - Effect of coal and quartz dust on ciliary activity in the respiratory tract.

PMID- 4360412
TI  - [Data on the biochemical mechanism of action of antidepressive
      psychopharmacologic agents].

PMID- 4360413
TI  - [The galactokinase deficiency in two human populations: Styria (Austria) and
      Franconia (Bavaria). A comparative investigation on gen frequency (author's
      transl)].

PMID- 4360414
TI  - Identifying the organism in vulvovaginal infections.

PMID- 4360416
TI  - Senescence and death of the conidiogenous cell in Stemphylium botryosum Wallroth.

PMID- 4360415
TI  - Infection in the severely traumatized patient.

PMID- 4360418
TI  - Cerebellar toxic effects from nitrofurantoin.

PMID- 4360417
TI  - Reye's syndrome: isolation of parainfluenza virus. Report of three cases.

PMID- 4360419
TI  - Adenosine 3',5'-monophosphate in cerebrospinal fluid. Effect of drugs and
      neurologic disease.

PMID- 4360420
TI  - Hexachlorophene neuropathy.

PMID- 4360421
TI  - A summary and evaluation of spin labels used as probes for biological membrane
      structure.

PMID- 4360423
TI  - Frog lactate dehydrogenase: kinetics at physiological enzyme levels.

PMID- 4360422
TI  - Membrane fusion.

PMID- 4360424
TI  - Bilirubin: a potent inhibitor of NAD+-linked isocitrate dehydrogenase.

PMID- 4360425
TI  - One-electron transfer reactions in biochemical systems. VII. Two types of
      electron outlets in milk xanthine oxidase.

PMID- 4360426
TI  - One-electron transfer reactions in biochemical systems. 8. Kinetic study of
      superoxide dismutase.

PMID- 4360427
TI  - Conversion of glycogen synthetase D of rat liver to a form that resembles
      synthetase D of skeletal muscle.

PMID- 4360428
TI  - Purification and characterization of a protein kinase in Tetrahymena cilia.

PMID- 4360429
TI  - On the nature of the acceleration of the methanesulfonylation of
      acetylcholinesterase by tetraethylammonium.

PMID- 4360430
TI  - Kinetics of the reaction of human renin with natural substrates and
      tetradecapeptide substrate.

PMID- 4360431
TI  - Effect of free magnesium and salts on the inorganic pyrophosphatase purified from
      a slightly halophilic Vibrio alginolyticus.

PMID- 4360432
TI  - A spin label investigation of some model membrane systems.

PMID- 4360433
TI  - Mass spectra of trimethylsilyl derivatives of homogeneous cerebrosides
      (monoglycosylceramides).

PMID- 4360434
TI  - Iron transport by phospholipids in a two phase system containing water and n
      pentanol.

PMID- 4360435
TI  - Muscular dystrophy in childhood.

PMID- 4360436
TI  - [Localization of creatine kinase in rat cardiac muscle mitochondria].

PMID- 4360437
TI  - [Effect of noradrenaline and cyclic 3',5'-adenosine monophosphate (cycl AMP) on
      enzymatic reduction of disulfides].

PMID- 4360438
TI  - [Combined effect of x-radiation and radical reaction inhibitors on the tumor and
      body of the tumor host].

PMID- 4360439
TI  - [Depressive effect of a sodium-free medium and choline on interneuronal
      electrical transmission in the leech C.N.S].

PMID- 4360440
TI  - [RNA content in the neuron-neuroglia system of the sympathetic ganglion and
      characteristics of synaptic transmission].

PMID- 4360441
TI  - Effects of quantal unit latency on statistics of Poisson and binomial
      neurotransmitter release mechanisms.

PMID- 4360442
TI  - Surgery of bilateral Wilms tumors: the role of renal transplantation.

PMID- 4360443
TI  - Congenital solitary kidney: a review of 74 cases.

PMID- 4360444
TI  - Plasma renin and aldosterone after renal transplantation.

PMID- 4360445
TI  - Adenylate cyclase activity in rat submandibular gland during postnatal
      development.

PMID- 4360446
TI  - The effects of silica dust and alveolar macrophages on lung fibroblasts grown in
      vitro.

PMID- 4360447
TI  - Further characterization of mono and diglyceride lipases in rat tissues.

PMID- 4360448
TI  - [Plasmatic coagulation factors in hyperlipoproteinemias].

PMID- 4360449
TI  - A possible direct action of ACTH on nerve and muscle.

PMID- 4360450
TI  - [Acute bovine mastitis caused by Clostridium perfringens, type A (author's
      transl)].

PMID- 4360451
TI  - [Correlation of numerically detected microcalcifications on the mammogram and in
      this manner diagnosed carcinomas and mastopathies].

PMID- 4360452
TI  - The interaction between Entamoeba histolytica and Schistosoma mansoni infections
      in mice.

PMID- 4360453
TI  - Indirect immunofluorescent staining of trophozoites of Entamoeba histolytica.

PMID- 4360454
TI  - Canine malignant mammary tumors. 3. Special types of carcinomas, malignant mixed
      tumors.

PMID- 4360455
TI  - Permanent mixed-field polyagglutinability (PMFP). I. Serological observations.

PMID- 4360456
TI  - Permanent mixed-field polyagglutinability (PMFP). II. Hematological, biophysical
      and biochemical observations.

PMID- 4360458
TI  - Molecular biology of pigment cells. Molecular controls in mammalian pigmentation.

PMID- 4360459
TI  - Action of cyclic AMP on pigment donation between mammalian melanocytes and
      keratinocytes.

PMID- 4360457
TI  - Ultrastructure and cell biology of pigment cells. Intracellular dynamics and the
      fine structure of melanocytes with special reference to the effects of MSH and
      cyclic AMP on microtubules and 10-nm filaments.

PMID- 4360460
TI  - [Renin-angiotensin-(aldosterone)-system-clinical aspects].

PMID- 4360461
TI  - On the fine structure of the Octopus iris.

PMID- 4360462
TI  - Effects of calcitonin on osteoclasts in vivo. An ultrastructural and
      histochemical study.

PMID- 4360463
TI  - Fine structural studies of rat adrenal cortices following prostaglandin
      administration.

PMID- 4360464
TI  - Fine structure and innervation of the avian adrenal gland. V. Innervation of
      interrenal cells.

PMID- 4360465
TI  - Association of renal allograft rejection with virus infections.

PMID- 4360466
TI  - In vivo effects of phytohaemoagglutinin on NAD-glycohydrolase activity and
      histological features of spleen, thymus and liver in the rat.

PMID- 4360468
TI  - Muscle spindle distribution in the masticatory muscle of the squirrel monkey
      (Saimiri sciurea).

PMID- 4360467
TI  - Glycogen metabolism and its control by norepinephrine in cardiac Purkinje fibers.

PMID- 4360469
TI  - Arsenical polyneuropathy-a clinical study.

PMID- 4360470
TI  - Progesterone binding in the immature rabbit and guinea pig uterus.

PMID- 4360471
TI  - In vivo action of vinblastine on thyroid ultrastructure and hormone secretion.

PMID- 4360472
TI  - Studies on cyclic nucleotides in the adrenal gland. IV. Effect of ACTH on cyclic
      nucleotides-dependent protein kinases in the adrenal gland.

PMID- 4360473
TI  - Effect of hypophysectomy and adrenalectomy on glucagon and insulin concentration.

PMID- 4360474
TI  - Effect of ACTH and camp on human adrenocortical growth and function in vitro.

PMID- 4360475
TI  - Hormonal control of adrenal RNA polymerase activities.

PMID- 4360476
TI  - Androgen receptors in mouse kidney: a study of male, female and androgen
      insensitive (tfm-y) mice.

PMID- 4360477
TI  - Studies on the nature of the hypothalamic estradiol-concentrating mechanism in
      the male and female rat.

PMID- 4360478
TI  - Oral contraceptives: ethinyl estradiol binds with higher affinity than mestranol
      to macromolecules from the sites of anti-fertility action.

PMID- 4360479
TI  - In vitro arterial perfusion of the dog adrenal.

PMID- 4360480
TI  - Inhibition of luteinization of transplanted rat ovarian follicles by
      polyphloretin phosphate.

PMID- 4360481
TI  - Estradiol receptor in rat testis.

PMID- 4360482
TI  - Purification and immunochemical studies of the protein-bound J substance from
      cattle serum.

PMID- 4360483
TI  - Carcinoembryonic antigen (CEA) in non digestive cancerous and normal tissues.

PMID- 4360484
TI  - Studies on the effect of cyclic-AMP on the ingibition of lipolysis by insulin &
      some oral hypoglycaemic agents.

PMID- 4360485
TI  - Viruses associated with clinical cases with special reference to poliomyelitis
      epidemic of 1971 in and around Chandigarh (Northern India).

PMID- 4360486
TI  - Changes in the contents of cholesterol and phosphatases in the lungs of rats
      exposed to mica dust.

PMID- 4360487
TI  - Chemotaxis of polymorphonuclear leukocytes in corneal inflammation: tissue injury
      in herpes simplex virus infection.

PMID- 4360489
TI  - Multiple sclerosis: an overview, with some observations on the spinal fluid
      protein.

PMID- 4360488
TI  - Effects of isoproterenol and cyclic AMP derivatives on cell division in cultured
      rat lenses.

PMID- 4360490
TI  - Detection of cyclic AMP in parotid saliva of normal individuals.

PMID- 4360492
TI  - A technique for relief of motor and sensory deficits occurring after anterior
      ulnar transposition. Technical note.

PMID- 4360491
TI  - Procarbazine hydrochloride in the treatment of brain tumors. Phase 2 study.

PMID- 4360493
TI  - Chromosome breakage in Drosophila melanogaster induced by a monofunctional
      alkylating agent (EMS).

PMID- 4360494
TI  - Investigation of the antifungal activity of the Nelex solution.

PMID- 4360495
TI  - Letter: Possible neuropathy from methyl N-butyl ketone.

PMID- 4360496
TI  - Letter: Cyclic AMP and corticosteroids.

PMID- 4360497
TI  - Letter: EBV and American Burkitt's lymphoma.

PMID- 4360498
TI  - Letter: Abdominal pain in hyperlipoproteinemia.

PMID- 4360499
TI  - Effects of cortical spreading depression on multiunit activity in the preoptic
      area and hypothalamus of the female rat.

PMID- 4360500
TI  - ACTH release in rats after removal of the medial hypothalamus.

PMID- 4360501
TI  - Physiological regulation of tissue-CRF.

PMID- 4360502
TI  - Spinal cord pathways involved in tourniquet stimulation of ACTH secretion.

PMID- 4360503
TI  - Influence of 6-hydroxydopamine on hypothalamic control of prolactin and ACTH
      secretion in the teleost fish, Tilapia mossambica.

PMID- 4360504
TI  - Neurologic manifestations in patients with mixed cryoglobulinemia.

PMID- 4360506
TI  - [Integration of oncogenic viral DNA, especially SV 40 and polyoma, into the cell
      DNA (author's transl)].

PMID- 4360505
TI  - [Fluorometric assay of proteins (author's transl)].

PMID- 4360507
TI  - [Cyclic AMP in cultured mammalian cells (author's transl)].

PMID- 4360508
TI  - Extra-articular pigmented villonodular synovitis affecting bone. The role of
      angiography as an aid in its differentiation from similar bone-destroying
      conditions.

PMID- 4360509
TI  - [Primary varicellous pneumonia].

PMID- 4360510
TI  - [Precocious puberty].

PMID- 4360511
TI  - [Electron histochemical study of the cytochrome oxidase activity of isolated
      nuclei and nuclear membranes].

PMID- 4360512
TI  - [Cytophotometric determination of the DNA content in experimental brain tumor
      cells. I. Transplantable strains of brain tumors in laboratory animals].

PMID- 4360513
TI  - [Leiomyofibroma of the minor omentum cavity associated with ovarian thecoma].

PMID- 4360514
TI  - [ORAL IMMUNIZATION AGAINST POX DISEASES. 4. Correlation between degree of
      attenuation of the vaccine virus, virulence for the 1-day-old chick and
      suitability for drinking water administration].

PMID- 4360515
TI  - [Antibodies against bovine and ovine C-type-virus-specific antigen in the serum
      of dairy cattle of a herd contaminated with leukosis (preliminary
      communication)].

PMID- 4360516
TI  - A selective medium for the isolation of Corynebacterium pyogenes.

PMID- 4360517
TI  - [Poland's syndrome. 17 new cases].

PMID- 4360518
TI  - [Our experience in hepatography with liposoluble substances].

PMID- 4360519
TI  - [Value of positive-contrast cervical myelography in the diagnosis of brachial
      plexus injuries, in adults].

PMID- 4360520
TI  - [Epidemiologic potential of enteroviruses in Moldavia].

PMID- 4360521
TI  - [Fatal perchloromethyl mercaptan intoxication (author's transl)].

PMID- 4360522
TI  - The effect of p,p'-DDT (Dicophane) and its main metabolites on the respiration of
      rat liver mitochondria.

PMID- 4360523
TI  - [Rib cartilage contains a collagenase inhibitor].

PMID- 4360524
TI  - Hypertension: a disease of abnormal circulatory control.

PMID- 4360525
TI  - A catecholamine secreting retroperitoneal glomangioma. A case report.

PMID- 4360526
TI  - Stepwise accumulation of autoregulated enzyme activities during the cell cycle of
      the eucaryote Chlorella.

PMID- 4360527
TI  - Enhancement of senescence in low passage human embryonic lung cells by an agent
      extracted from phase 3 cells.

PMID- 4360528
TI  - The effect of photosensitizing dyes on the 3H-thymidine incorporation of cells
      grown in vitro.

PMID- 4360529
TI  - Myogenic cells derived from murine sarcoma induced mouse tumours: DNA synthesis
      and the effects of simian virus 40 infection.

PMID- 4360530
TI  - Activation of nuclear chromatin and the release from contact-inhibition of 3T3
      cells.

PMID- 4360531
TI  - Maturation-stimulation effect of brain extract and dibutyryl cyclic AMP on
      dissociated embryonic brain cells in culture.

PMID- 4360532
TI  - Citric acid-sonication method for the isolation of nucleoli.

PMID- 4360533
TI  - Deoxyribonuclease in sea urchin embryos. Comparison of the activity present in
      developing embryos, in nuclei, and in mitochondria.

PMID- 4360535
TI  - [Structural defects during spore formation in actinomycetes].

PMID- 4360534
TI  - Differential sensitivity of antigen- and mitogen-stimulated human leukocytes to
      prolonged inhibition of potassium transport.

PMID- 4360536
TI  - Nature of the specificity of alcohol coupling to L-alanine transport into
      isolated membrane vesicles of a marine pseudomonad.
AB  - Ethanol stimulated the uptake of l-alanine into isolated membrane vesicles of a
      marine pseudomonad at a rate and to an extent comparable with that obtained with
      reduced nicotinamide adenine dinucleotide (NADH) or the artificial electron donor
      ascorbate-N, N, N', N'-tetramethyl-p-phenylenediamine (ascorbate-TMPD). Methanol
      and branched-chain alcohols had little or no capacity to energize transport. No
      quantitative relationship was found between the ability of a compound to induce
      oxygen uptake and to energize transport, since with ethanol initial rates of
      oxygen uptake were approximately 4% of that obtained with NADH or ascorbate-TMPD.
      Cytochrome analysis revealed that NADH and ethanol reduced cytochromes b and c,
      whereas ascorbate-TMPD coupled primarily at the level of cytochrome c.
      Approximately 25% of the cytochromes reduced by dithionite were reducible by
      ethanol. Ethanol reduction of both cytochromes b and c was prevented by 2-heptyl
      4-hydroxyquinoline-N-oxide, p-chloromercuribenzoate, N-ethylmaleimide, and
      iodoacetate. The ethanol- and NADH-energized transport systems for l-alanine were
      subject to quantitatively similar inhibition by cyanide, 2-heptyl-4
      hydroxyquinoline-N-oxide, 2, 4-dinitrophenol, and the sulfhydryl reagents p
      chloromercuribenzoate, N-ethylmaleimide, and iodoacetate. In contrast, for
      ascorbate-TMPD-driven transport, only cyanide and 2, 4-dinitrophenol remained
      fully effective as inhibitors, p-chloromercuribenzoate was only half as
      effective, and the other compounds stimulated transport. Inhibition of ethanol
      oxidation strikingly paralleled the inhibition of ethanol-driven transport for
      each of the inhibitors, including 2, 4-dinitrophenol. Marked differences between
      inhibition of oxygen uptake and inhibition of transport were observed when NADH
      or ascorbate-TMPD were the electron donors. The data indicate that only a small
      proportion of the respiratory chain complexes in the membrane vesicles are
      involved in transport and these are efficiently coupled to ethanol oxidation. The
      results also suggest that when 2, 4-dinitrophenol inhibits transport it is not
      acting as an uncoupling agent.

PMID- 4360537
TI  - Specific electron donor-energized transport of alpha-aminoisobutyric acid and K+
      into intact cells of a marine pseudomonad.
AB  - The transport of alpha-aminoisobutyric acid and K(+) into K(+)-depleted cells of
      a marine pseudomonad (ATCC 19855) was stimulated strongly by ethanol, reduced
      nicotinamide adenine dinucleotide (NADH), and ascorbate-reduced N, N, N', N'
      tetramethyl-p-phenylenediamine. In the presence of the quinone inhibitor 2-heptyl
      4-hydroxyquinoline-N-oxide, only ascorbate-reduced N, N, N', N'-tetramethyl-p
      phenylenediamine was active. Primary and secondary, but not tertiary, alcohols
      from ethanol to n-amyl alcohol stimulated both alpha-aminoisobutyric acid and
      K(+) transport and were oxidized by the cells. Malate and succinate, which were
      oxidized rapidly by the cells, had little or no capacity to energize the
      transport of alpha-aminoisobutyric acid into K(+)-depleted cells but were
      partially effective in promoting K(+) uptake. Ethanol stimulated the transport of
      alpha-aminoisobutyric acid into K(+)-preloaded cells. The transport of both alpha
      aminoisobutyric acid and K(+) was inhibited 20% by iodoacetate, 85% by N
      ethylmaleimide, and 90 to 100% by both NaCN and p-chloromercuribenzoate. The
      addition of Na(3)Fe(CN)(6) permitted the ethanol-induced transport of alpha
      aminoisobutyric acid into K(+)-preloaded cells in the presence of NaCN, but
      little or no uptake of alpha-aminoisobutyric acid or of K(+) into K(+)-depleted
      cells under the same conditions. The transport of alpha-aminoisobutyric acid into
      K(+)-depleted cells required both K(+) and an electron donor. The oxidation of
      NADH and ethanol by K(+)-depleted cells was stimulated strongly by K(+).
      Parallels between these studies and those with membrane vesicles show that
      results with membrane vesicles of the marine pseudomonad have physiological
      significance for the intact cells. The results support the conclusion that the
      energy for the active transport of both alpha-aminoisobutyric acid and K(+) into
      cells of this organism is provided by electron flow through a region of the
      respiratory chain lying between cytochrome c and O(2).

PMID- 4360538
TI  - De novo purine synthesis in vegetative cells and myxospores of Myxococcus
      xanthus.
AB  - This study was designed to determine whether vegetative cells and myxospores of
      Myxococcus xanthus were capable of classical de novo purine biosynthesis. To
      answer this question, vegetative and myxospore extracts of M. xanthus FBa were
      tested for their ability to synthesize the second de novo intermediate, 5'
      phosphoribosylglycinamide, from beginning precursors either by way of
      phosphoribosyl-pyrophosphate amido transferase (EC 2.4.2.14) or ribose-5
      phosphate amino transferase. Both the amido and amino transferase routes occurred
      in both types of extracts, and both enzymes appear to be present at about the
      same level (per milligram of protein) in vegetative cells, myxospores, and in a
      bacterial prototype, Salmonella typhimurium. The dose response of the vegetative
      and myxospore forms of both enzymes towards adenosine 5'-monophosphate (AMP) and
      guanosine 5'-monophosphate (GMP) suggests that the allosteric structure of both
      enzymes is changed little by sporulation. Both enzymes were inhibited to varying
      degrees by a variety of purine nucleotides besides AMP, GMP, and 3':5' cyclic
      AMP.

PMID- 4360539
TI  - Regulation of tryptophan biosynthesis in Saccharomyces cerevisiae: mode of action
      of 5-methyl-tryptophan and 5-methyl-tryptophan-sensitive mutants.
AB  - In a wild-type strain of Saccharomyces cerevisiae the tryptophan analogue dl-5
      methyl-tryptophan (5MT) causes only a slight reduction of the growth rate. Uptake
      experiments indicate that the limited inhibition is partly due to low levels of
      5MT inside the cell. On the other hand, this low concentration of 5MT leads to an
      increase in the activity of the tryptophan-biosynthetic enzymes. Evidence is
      presented that suggests that 5MT acts primarily through feedback inhibition of
      anthranilate synthase, the first enzyme of the pathway. A number of 5MT-sensitive
      mutants have been isolated, characterized, and assigned to one of the following
      three classes: class I, strains with altered activity and/or feedback sensitivity
      of anthranilate synthase; class II, strains with elevated uptake of 5MT; class
      III, mutants with altered regulation of the tryptophan-biosynthetic enzymes,
      which do not exhibit increases in activity in the presence of 5MT. This failure
      to exhibit increased enzyme activities in mutants of class III can also be
      observed after tryptophan starvation. Two mutants of class III show high
      sensitivity towards 3-amino-1,2,4-triazole. They can not exhibit derepression of
      some histidine- and arginine-biosynthetic enzymes under conditions that lead to
      an increase in these same enzymes in the wild-type strain.

PMID- 4360540
TI  - Fatty acid degradation in Escherichia coli: requirement of cyclic adenosine
      monophosphate and cyclic adenosine monophosphate receptor protein for enzyme
      synthesis.
AB  - The strong repression of inducible synthesis of the enzymes of fatty acid
      degradation by glucose can be partially relieved by the addition of cyclic
      adenosine 3',5' monophosphate (cyclic AMP) to the growth medium. This reversal of
      the glucose effect by cyclic AMP is not observed in a mutant (K29) that is unable
      to grow on fatty acids as sole carbon source and that was found to synthesize low
      levels of several enzymes specified by the fad regulon. In a revertant selected
      for the ability to grow on oleate these effects are concomitantly relieved. By
      both genetic (co-transduction of the mutation with the strA locus) and
      biochemical experiments (an extract of the mutant strain does not show the cyclic
      AMP-dependent stimulation of the deoxyribonucleic acid-directed in vitro
      synthesis of the enzymes of the gal operon), it is demonstrated that the mutant
      lacks functional cyclic AMP receptor protein (CR protein). It is concluded that,
      like many other inducible enzyme systems, expression of the enzymes of the fad
      system requires cyclic AMP and the CR protein.

PMID- 4360541
TI  - Isolation and characterization of temperature-sensitive mutants of host-dependent
      Bdellovibrio bacteriovorus 109D.
AB  - A variety of temperature-sensitive mutants of host-dependent Bdellovibrio
      bacteriovorus 109D were selected after ethyl methane sulfonate mutagenesis.
      Mutants that demonstrated plaque-forming ability reversion frequencies of 10(-8)
      to 10(-9) were chosen for further study. Representatives of these mutants were
      then characterized by phase-contrast and electron microscopy, temperature-shifted
      one-step growth experiments, attachment kinetics, and macromolecular
      capabilities. Representative mutants demonstrate various types of blockage
      corresponding to the previously described morphological stages of Bdellovibrio
      predatious life cycle, i.e., attachment blockage (109D153), penetration blockage
      (109D3 and 109D48), and blockage of intracellular growth (109D4 and 109D152). The
      time of release from temperature repression for the mutant classes was found to
      correspond to the apparent morphological stage of blockage via temperature
      shifted, one-step growth experiments. Mutants characterized as exhibiting
      blockage in the penetration or intracellular stages of the infection cycle
      exhibited, at the permissive and nonpermissive temperatures, kinetics of
      attachment to Escherichia coli WP2 similar to those of the wild type. One mutant,
      109D153, exhibited depressed attachment at the restrictive temperature even
      though the Bdellovibrio cells were motile. The extent of 38.5 C attachment of
      109D153 to E. coli is at the same level as that of wild-type 109D to Bacillus
      subtilis, a gram-positive, non-host organism. Subsequent detachments were
      revealed in the wild-type 109D-B. subtilis or mutant 109D153-Escherichia coli
      (38.5 C) cultures. These studies reveal a biphasic attachment phenomenon in the
      early interaction of Bdellovibrio with its host. It appears that, at the
      restrictive temperature, 109D153 is capable only of the initial, nonspecific type
      of attachment.

PMID- 4360542
TI  - Isolation of a regulatory mutant of fructose-1,6-diphosphatase in Saccharomyces
      carlsbergensis.
AB  - By selecting for growth on glycerol, but absence of growth on glucose, a mutant
      of Saccharomyces carlsbergensis was isolated which does not grow on glucose,
      fructose, mannose, or sucrose, which shows long-term adaptation to maltose, but
      which can grow normally on galactose, ethanol, or glycerol. In the mutant,
      fructose diphosphatase is not inactivated after the addition of glucose, fructose
      or mannose to the medium, resulting in the simultaneous presence of fructose
      diphosphatase and phosphofructokinase activity. Under these conditions, a cycle
      is probably catalyzed between fructose-6-phosphate and fructose-1,6-diphosphate,
      resulting in the net consumption of adenosine triphosphate and an immediate stop
      of protein synthesis.

PMID- 4360543
TI  - Reversion of frameshift mutations by mutator genes in Escherichia coli.
AB  - The Escherichia coli mutator genes mutU4, mutS3, and mut-25 (a possible allele of
      mutL), previously known to induce transitional base changes, increased
      significantly the frequencies of reversion of lacZ frameshift mutations. mutT1,
      previously shown to induce only the transversion of adenine-thymine to cytosine
      guanine, had no effect on the reversion of lacZ frameshift mutations. With
      mutator genes other than mutT1, small increases were found in the frequencies of
      reversion of trpA frameshift mutations.

PMID- 4360544
TI  - Antisera to human cytomegaloviruses prepared in the guinea pig: specific
      immunofluorescence and complement fixation tests.

PMID- 4360545
TI  - Evidence for in vivo protection against murine-sarcoma virus-induced tumors by T
      lymphocytes from immune animals.

PMID- 4360546
TI  - In vitro detection of immune responses to MTV-induced mammary tumors: activity of
      spleen cell preparations from both MTV-free and MTV-infected mice.

PMID- 4360547
TI  - Lymphocyte interferon production and transformation after Herpes simplex
      infections in humans.

PMID- 4360548
TI  - Ruptured abdominal aortic aneurysm presenting with peripheral neuropathy.

PMID- 4360549
TI  - Adrenocortical structure and function in rats bearing an adrenocorticotrophic
      hormone, growth hormone, and prolactin-secreting tumor.

PMID- 4360550
TI  - [Effect of ACTH and glucocorticoids on the secretion of renin in normal subjects
      and in patients with adrenal insufficiency].

PMID- 4360552
TI  - Perspectives on the renin-angiotensin-aldosterone system in hypertension.

PMID- 4360553
TI  - Alcohol and cancer.

PMID- 4360551
TI  - Comparison of insulin and proinsulin storage in an islet adenoma and adjacent
      pancreas.

PMID- 4360554
TI  - [Tissue respiration of the brain structures in changed functional condition of
      the adrenal glands in experimental hypothermia].

PMID- 4360555
TI  - [In vivo study of the NAD-NAD-H system in the myocardium].

PMID- 4360557
TI  - Hypothalamic inputs: methods, and five examples.

PMID- 4360558
TI  - Basic electrophysical mechanisms in neuroendocrinology.

PMID- 4360556
TI  - [Pathogenesis and correction of liver circulation in chronic hepatitis and liver
      cirrhosis].

PMID- 4360559
TI  - Hypothalamic mechanisms controlling pituitary function.

PMID- 4360561
TI  - [Modern views on the treatment of multiple sclerosis].

PMID- 4360560
TI  - [Parasitological problems in diseases of colon (author's transl)].

PMID- 4360562
TI  - Activation of lymphoid leucosis in chicks by irradiation.

PMID- 4360563
TI  - [Recovery or remission of Cushing's disease following long term administration of
      OP'DDD in seventeen patients (author's transl)].

PMID- 4360564
TI  - [Production and metabolic clearance rates of cortisol in primary hypothyroidism
      (author's transl)].

PMID- 4360565
TI  - [Physiopathological basis of neonatal asphyxia].

PMID- 4360566
TI  - [Rapid diagnosis of respiratory virus diseases by immunofluorescence of infected
      cell cultures].

PMID- 4360567
TI  - [Effects of Sabin's antipoliomyelitis vaccination on the circulation of
      cytopathogenic enteric viruses in the province of Bari].

PMID- 4360568
TI  - [Biochemical research on "pathogenic" staphylococci].

PMID- 4360569
TI  - [Proceedings: Use of gamma camera in radioisotope surgery].

PMID- 4360570
TI  - [Proceedings: Experimental studies of malignant transformation of ovarian
      tissue].

PMID- 4360571
TI  - [Proceedings: Morphology, cytophotometry and clinical significance of 3 in situ
      growing breast neoplasms: comedo carcinoma, lobular carcinoma in situ and
      intracystic carcinoma].

PMID- 4360572
TI  - [Proceedings: Estrogen receptors in mamma carcinomas and course following
      endocrine therapy].

PMID- 4360573
TI  - [Proceedings: Uterine enzymes in pregnancy].

PMID- 4360574
TI  - [Proceedings: Demonstration of specific estradiol receptors in human uterus under
      various endocrine conditions].

PMID- 4360575
TI  - [Proceedings: Binding of steroid hormones in myomas].

PMID- 4360576
TI  - [Proceedings: Labor induction using intra-animal presomen administration].

PMID- 4360577
TI  - [Angiofibroma of the hepatic round ligament].

PMID- 4360578
TI  - Home care program cuts dollars and days.

PMID- 4360579
TI  - The Baycrest experience: make your beds go further.

PMID- 4360580
TI  - [Clinical ophthalmoscopy in arterial hypertension].

PMID- 4360582
TI  - Differential inhibition of histoformative aggregation of rat hepatoma cells in
      culture by concanavalin-A.

PMID- 4360581
TI  - Further studies on antibodies to early antigens induced by Epstein-Barr virus in
      nasopharyngeal carcinoma patients.

PMID- 4360583
TI  - Modes of Epstein-Barr virus infection in human floating cell lines.

PMID- 4360584
TI  - Tumor inhibitory effect of a new series of methanesulfonate of aminoglycols.

PMID- 4360585
TI  - Heterogeneity of catalase in Morris hepatomas as revealed by isoelectric focusing
      and deae-cellulose column chromatography.

PMID- 4360586
TI  - Assay of Epstein-Barr virus by immunofluorescence.

PMID- 4360587
TI  - Brain tumors induced in adult monkeys by Schmidt-Ruppin strain of Rous sarcoma
      virus.

PMID- 4360588
TI  - [Determination of small amounts of titanium and Th232 in biological material in
      the presence of the sigma-RE elements, Nb, Ta, Al, SiO2 and a series of other
      elements].

PMID- 4360589
TI  - Separation of dl-2-(3-phenoxyphenyl)propionic acid (fenoprofen) from its
      intermediates by thin layer chromatography.

PMID- 4360590
TI  - An isolation and cleanup procedure for low levels of organochlorine pesticide
      residues in fats and oils.

PMID- 4360591
TI  - Bluetongue virus transmission with Culicoides variipennis via embryonating
      chicken eggs.

PMID- 4360592
TI  - [Water and electrolyte imbalance and the renin-angiotensin-aldosterone system].

PMID- 4360593
TI  - [Sites and mechanism of action of diuretic agents].

PMID- 4360594
TI  - [Change in the acid phosphatase activity of susceptible cells at the early stages
      of their interaction with Sendai and influenza A2 (Hong Kong) 68 viruses].

PMID- 4360595
TI  - [Inflammatory carcinoma of the breast. Report of 2 cases (author's transl)].

PMID- 4360596
TI  - Physiology of neuromuscular transmission.

PMID- 4360597
TI  - [Lung cancer in animals (author's transl)].

PMID- 4360599
TI  - Hepatic scintoscans.

PMID- 4360598
TI  - The work of the primary liver cancer research project: the value of liver
      function tests in the diagnosis of primary cancer of the liver in the Bantu.

PMID- 4360600
TI  - [Effects of psychotropic and hypnotic drugs on the human nocturnal sleep
      (author's transl)].

PMID- 4360601
TI  - [Long-term treatment of arthrosis with Ecma].

PMID- 4360602
TI  - [Vacuolation of skeletal muscle fibers. VI. Development of vacuoles during efflux
      of sugars and mineral ions].

PMID- 4360603
TI  - [Function of the adrenal cortex and ovulation process in the swine].

PMID- 4360604
TI  - [Studies on adrenal cortex function in farm animals using cortisol and
      corticosterone determinations according to the principle of competitive protein
      binding analysis. 2. Studies in pigs].

PMID- 4360605
TI  - [The relationship between survival time of mice and the dose of intravenously
      administered toxin of the agent of gas gangrene].

PMID- 4360606
TI  - [Effect of maternally administered calcitonin on bone development. Histological
      and enzyme histochemical studies on newborn rats].

PMID- 4360607
TI  - [Morphological and functional aspects of cellular autophagy].

PMID- 4360608
TI  - [Current problems in the cytochemistry of lysosomal hydrolases].

PMID- 4360610
TI  - [Glomus jugulare tumors].

PMID- 4360609
TI  - [Nasopharyngeal angiofibromas].

PMID- 4360612
TI  - [Ultrastructure of the cardiac muscle in experimental tonsillogenic
      myocardiodystrophy of neurogenic origin].

PMID- 4360611
TI  - [Adenomas and adenocarcinomas of the urinary bladder].

PMID- 4360613
TI  - [Amplitude increase in frog neuromuscular junction postsynaptic potentials in
      conditions of combined direct and indirect stimulation of muscle fibers].

PMID- 4360614
TI  - [Effect of N-alkyl-N-nitrosourea on the protein-synthesizing system of liver and
      hepatoma 22a cells].

PMID- 4360615
TI  - The modern face of rheumatic fever.

PMID- 4360616
TI  - [ACTH and MSH].

PMID- 4360617
TI  - [Correlation between the use of steroid hormones and the response in rapid ACTH
      tests].

PMID- 4360618
TI  - [Effects of LATS on cyclic-AMP in the avian thyroid].

PMID- 4360619
TI  - [Determination of low unit hCG Higonavis: application to the management of
      chorionic tumor].

PMID- 4360620
TI  - [Calcitonin analysis].

PMID- 4360621
TI  - Fibrinous pseudo-intimas within impermeable silastic-nylon velour. II.
      Development of "neointima".

PMID- 4360622
TI  - Hemolytic activity of mica dust and its relation to polyvinylpyridine N-oxide.

PMID- 4360623
TI  - Frey's syndrome: diagnosis and treatment.

PMID- 4360624
TI  - [Liver scanning].

PMID- 4360625
TI  - [Selective abdominal arteriography in gastrointestinal pathology].

PMID- 4360626
TI  - Replication of the resident non-defective SV40 in transformed human cells
      superinfected with DNA from a temperature-sensitive SV40 mutant.

PMID- 4360627
TI  - Relationship between cell-interaction and antiviral activity of polyriboinosinic
      acid-polyribocytidylic acid in different cell cultures.

PMID- 4360628
TI  - Electron microscopic observations on the mechanisms of entry of simian foamy
      virus in HEp-2 cells.

PMID- 4360629
TI  - Characterization of Herpes simplex virus types 1 and 2 adapted to growth at 25
      degrees C.

PMID- 4360630
TI  - Mass production of human interferon in diploid cells stimulated by poly-I:C.

PMID- 4360631
TI  - Haemolysis by Sendai virus: involvement of a virus protein component.

PMID- 4360632
TI  - A comparative study of Tanapox and Yaba viruses.

PMID- 4360633
TI  - Interferon assay based on the inhibition of double-stranded reovirus RNA
      accumulation in mouse L cells.

PMID- 4360634
TI  - Virocidal cleavage of disulphide bonds within structural proteins of Sendai
      virus.

PMID- 4360635
TI  - Blocking of the virus-enhancing activity of 5-methyl-2-D-ribobenzimidazole (MRB).

PMID- 4360637
TI  - Spontaneous disappearance of tumorigenicity in a polyoma virus-induced neoplasm
      carried in vitro.

PMID- 4360636
TI  - Behavior of human cytomegaloviruses in cell cultures of bovine and simian origin.

PMID- 4360638
TI  - Regional cyclic nucleotide phosphodiesterase activity in cat central nervous
      system: effects of benzodiazepines.

PMID- 4360639
TI  - Neurogenic hypercholesterolemia: influence upon lipoproteins.

PMID- 4360640
TI  - The binding of 131-I-HCG to mature follicles isolated from the rabbit ovary.

PMID- 4360641
TI  - Reversible inhibition by hyaluronidase of the insulinotropic action of
      tolbutamide in isolated hamster pancreatic islets.

PMID- 4360643
TI  - Ontogenesis of circadian pituitary-adrenal periodicity in rats affected by
      neonatal treatment with ACTH.

PMID- 4360642
TI  - Tilorone: its selective effects on humoral and cell-mediated immunity.

PMID- 4360644
TI  - Lack of correlation between initial vascular resistance and responses to
      vasoconstrictor stimuli in the perfused canine hindpaw.

PMID- 4360645
TI  - A survey of cats and humans for prevalence of feline leukemia-sarcoma virus
      neutralizing serum antibodies.

PMID- 4360646
TI  - Effect of heparin on the kinetics of guinea pig and human postheparin lipase
      activity.

PMID- 4360647
TI  - Complement-fixing antibodies reactive with Epstein-Barr virus in sera of
      marmosets and prosimians.

PMID- 4360648
TI  - Lack of interaction between glucocorticoids and the kallikrein-kinin system.

PMID- 4360649
TI  - Microneutralization test for detection of rhinovirus antibodies.

PMID- 4360651
TI  - [Effect of ionizing radiation on induction of glucose-6-phosphatase synthesis in
      rat liver in embryogenesis].

PMID- 4360650
TI  - Studies of cyclic AMP effect on release of unsaturated vitamin B 12 binding
      capacity from human blood cells.

PMID- 4360652
TI  - [Muscle response to repeated stimulation in Steinert's disease].

PMID- 4360653
TI  - [Usefulness of the stereo-electroencephalographic chronic exploration in
      epilepsy].

PMID- 4360654
TI  - [Clinical and electroencephalographic contribution to the study of abdominal
      epilepsy].

PMID- 4360655
TI  - Ocular illness in association with adenovirus type 3 infection. An epidemic of
      conjunctivitis and keratoconjunctivitis in Stockholm 1969.

PMID- 4360656
TI  - Osteoblastic multiple myeloma.

PMID- 4360657
TI  - [Biochemical changes in different areas of the brain during natural sleep and its
      disorders].

PMID- 4360658
TI  - [Technic of hip joint arthrodesis with reference to subsequent alloarthroplastic
      treatment].

PMID- 4360659
TI  - [The theoretical principles of manual medicine].

PMID- 4360661
TI  - Spironolactone inclusions in an aldosteronoma.

PMID- 4360660
TI  - Cold-reactive antibodies in a case of congenital cytomegalovirus infection.

PMID- 4360662
TI  - Angiographic evaluation of primary malignant hepatocellular tumors in children.

PMID- 4360663
TI  - Phlebo-arterio-urography in the assessment of abdominal masses in children.

PMID- 4360665
TI  - [Canalicular cells and oncocytes in the human pancreas. Comparative study on the
      normal condition and in chronic pancreatitis].

PMID- 4360664
TI  - B-scan diagnostic ultrasound in the pediatric patient.

PMID- 4360666
TI  - [Histochemical study of a recurrent mixed tumor of the parotid gland].

PMID- 4360667
TI  - Prognostic factors in carcinoma of the stomach.

PMID- 4360668
TI  - Studies on the reduction of tetrazolium salts. I. The isolation and
      characterisation of a half-formazan intermediate produced during the reduction of
      neotetrazolium chloride.

PMID- 4360669
TI  - The anti-anaphylactic actions of disodium cromoglycate, theophylline,
      isoprenaline and prostaglandins.

PMID- 4360670
TI  - Thin layer chromatography and in situ fluorometry for the quantitative
      determination of dimethoate and malathion in lettuce.

PMID- 4360671
TI  - Microbiological methods. Collaborative study of the alpha-toxin method for
      estimating population levels of Clostridium perfringens in food.

PMID- 4360672
TI  - Anaerobic synthesis of apocytochrome oxidase and assembly of the holoenzyme in
      yeast protoplasts.

PMID- 4360673
TI  - Coproporphyrin 3, inhibitor of the synthesis of cytochrome oxidase in anaerobic
      yeast protoplasts.

PMID- 4360674
TI  - Interaction of an active glycopeptide from chick skin collagen (alpha 1-CB5) with
      human platelets.

PMID- 4360675
TI  - Spectroscopic studies on the conformation of cytochrome c and apocytochrome c.

PMID- 4360676
TI  - Interaction of nucleotides with liver uridine diphosphate-glucose-4'-epimerase.

PMID- 4360677
TI  - Glucocorticoid receptors in rat thymocytes. Interactions with the
      antiglucocorticoid cortexolone and mechanism of its action.

PMID- 4360679
TI  - Studies on the regulation of gluconeogenesis in isolated rat liver cells by
      epinephrine and glucagon.

PMID- 4360678
TI  - Effects of 25-hydroxyvitamin D3 on rat duodenum, jejunum, and ileum. Correlation
      of calcium active transport with tissue levels of vitamin D3 metabolites.

PMID- 4360680
TI  - Protein and glycoprotein subunit composition of plasma membrane from chick embryo
      fibroblasts.

PMID- 4360681
TI  - Characterization of protein kinases from rabbit reticulocytes.

PMID- 4360682
TI  - The role of ribosomal proteins L7 and L-12 in polypeptide chain initiation in
      Escherichia coli.

PMID- 4360683
TI  - Structural study of the blood group A active glycolipids of hog gastric mucosa.

PMID- 4360684
TI  - Testicular adenosine 3':5'-monophosphate-dependent protein kinase. Regulation by
      follicle-stimulating hormone.

PMID- 4360685
TI  - 1 Alpha,25-dihydroxycholecalciferol receptors in intestine. I. Association of 1
      alpha,25-dihydroxycholecalciferol with intestinal mucosa chromatin.

PMID- 4360686
TI  - 1 Alpha,25-dihydroxycholecalciferol receptors in intestine. II. Temperature
      dependent transfer of the hormone to chromatin via a specific cytosol receptor.

PMID- 4360687
TI  - Rabbit muscle phosphofructokinase. II. Product and dead end inhibition.

PMID- 4360688
TI  - The regulation of lipogenesis by cyclic nucleotides in intact hepatocytes
      prepared by a simplified technique.

PMID- 4360689
TI  - Enzyme-catalyzed free radical reactions with nicotinamide adenine nucleotides.
      II. Lactate dehydrogenase-catalyzed oxidation of reduced nicotinamide adenine
      dinucleotide by superoxide radicals generated by xanthine oxidase.

PMID- 4360690
TI  - Thin-layer chromatography of various analgesics, antipyretics and anti
      inflammatory agents.

PMID- 4360691
TI  - Cerebral arterial spasm. 1. In vitro contractile activity of vasoactive agents on
      canine basilar and middle cerebral arteries.

PMID- 4360692
TI  - [Compensatory character of the reactions of the peripheral vessels under
      conditions of a change in the tonicity of the vascular wall].

PMID- 4360693
TI  - [Study of patients with lesions of the peripheral nervous system].

PMID- 4360694
TI  - Cellular action of antidiuretic hormone in nephrogenic diabetes insipidus.

PMID- 4360695
TI  - Effect of heterologous transplantation of H4-II-E rat hepatoma cells into the
      cheek pouch of hydrocortisone treated hamsters.

PMID- 4360696
TI  - [Postradiation changes in oxidation-reduction systems in rat tissues].

PMID- 4360697
TI  - Detection of Australia antigen (HBAg) in blood donors and hepatoma patients in
      Mozambique.

PMID- 4360698
TI  - [Detection of an antigen of the pox virus in heterogenous cell systems].

PMID- 4360699
TI  - Effects of 6-OH-dopamine on the autonomic nerves of the rabbit myometrium.

PMID- 4360700
TI  - Group I inhibition in Ib excited ventral spinocerebellar tract neurones.

PMID- 4360701
TI  - Vascular and metabolic effects of theophylline, dibuturyl cyclic AMP and
      dibuturyl cyclic GMP in canine subcutaneous adipose tissue in situ.

PMID- 4360702
TI  - Observations on closed tissue cultures of sympathetic ganglia of chick embryos in
      media buffered with N-tris-(hydroxymethyl) methyl-glycine or N-2-hydroxy
      ethylpiperazine-N-2-ethanesulfonic acid.

PMID- 4360704
TI  - Langerhans cells in cell culture. Survival and identification.

PMID- 4360703
TI  - A long term study on the ocular lesions in streptozotocin diabetic rats.

PMID- 4360705
TI  - Stimulation of dendritogenesis in human melanocytes by dibutyryl adenosine 3', 5'
      cyclic monophosphate in vitro.

PMID- 4360707
TI  - [Anthracoid abscess of the liver. A further case].

PMID- 4360706
TI  - [Frequency of cytomegalic virus in 1 to 15-year-old children].

PMID- 4360708
TI  - The immunodepressive effect of infectious bursal disease virus in chickens.

PMID- 4360709
TI  - Investigation of an increase of solid tumors in chickens vaccinated against
      Marek's disease.

PMID- 4360710
TI  - Atypical fowlpox in a poultry farm in Illinois.

PMID- 4360711
TI  - Influence of mitochondria on phospholipid synthesis in preparations from rat
      liver.
AB  - 1. The addition of mitochondria to an incubation system containing the soluble
      and microsomal fractions of rat liver enhances severalfold the incorporation of
      each of ethanolamine, phosphorylethanolamine and CDP-ethanolamine into
      phosphatidylethanolamine. 2. In the presence of microsomal, mitochondrial and
      soluble fractions, CDP-ethanolamine exhibits the greatest initial rate of
      incorporation (approx. 6nmol/h per mg of protein), being slightly faster than
      that of phosphorylethanolamine (approx. 5nmol/h per mg of protein). Incorporation
      of ethanolamine proceeds very slowly for the first 20min and only after 30min
      gives rates approaching those of the other two precursors. 3. By using a
      substrate ;dilution' technique it was shown that in the reconstituted system the
      affinity of each of the enzymes for their respective substrates is very high:
      10mum for ethanolamine, 25mum for phosphorylethanolamine and 5mum for CDP
      ethanolamine. 4. Isolation of the mitochondrial and microsomal fractions from the
      medium after incubation together with phosphorylethanolamine showed that about
      70% of the total radioactivity was present in the microsomal fraction and about
      30% in the mitochondria after only 20min. Similar experiments with ethanolamine
      as precursor revealed that after 20min only about 15% of the total radioactivity
      was present in the mitochondria but that after 40min about 30% was present in
      this fraction. 5. Heating and phospholipase treatment of mitochondria, but not
      freeze-thawing, eliminated the stimulatory effect of mitochondria on phospholipid
      synthesis. 6. The reconstituted system exhibits an absolute requirement for
      Mg(2+) (2mm gave maximal rates) and is inhibited by very low concentrations of
      Ca(2+) (100mum-Ca(2+) produced half-maximal inhibition with 3mm-Mg(2+)). Further
      addition of Mg(2+) overcame the Ca(2+) inhibition, suggesting that the inhibitory
      effect is readily reversible. 7. The concept that modification of the
      Mg(2+)/Ca(2+) ratio is a means of controlling the rate of cellular phospholipid
      synthesis is introduced.

PMID- 4360712
TI  - Plasma lipoproteins and the synthesis and turnover of plasma triglyceride in
      normal and genetically obese mice.
AB  - 1. Lipoproteins in the plasma of mice were characterized by agarose-gel
      chromatography and polyacrylamide-gel electrophoresis: genetically obese (ob/ob)
      mice exhibited hyperlipoproteinaemia (compared with lean mice), largely owing to
      an increase in the concentration of cholesterol in high-density lipoprotein.
      Plasma concentrations of triglyceride and phospholipid were not markedly
      increased in genetically obese mice. 2. The formation of glycerolipids in liver
      and plasma was investigated with (14)C-labelled precursors. The synthesis of
      hepatic triglyceride and phospholipid from glucose or palmitate was enhanced in
      ob/ob mice, compared with lean mice. The rate of entry of triglyceride into
      plasma, calculated from the time-course of incorporation of (14)C from
      [(14)C]palmitate into plasma triglyceride, was increased in ob/ob mice (0.5mumol
      of fatty acid/min, compared with 0.2 in lean mice). 3. The removal from plasma of
      murine lipoprotein triglyceride-[(14)C]fatty acid was increased in ob/ob mice
      (half-time 2.2min, compared with 7.2min in lean mice). Similar results were
      obtained with an injected lipid emulsion (Intralipid). 4. From these
      measurements, estimates of the rates of turnover of plasma triglyceride in mice
      (fed on a mixed diet, female, 3 months old) are about 1.0mumol of fatty acid/min
      in ob/ob mice, and 0.25 in lean mice. 5. The major precursor of hepatic and
      plasma triglyceride in lean and ob/ob mice was calculated to be plasma free fatty
      acid. 6. These results are discussed, in connexion with the role of the liver in
      triglyceride metabolism in mice, especially in relation to genetic obesity.

PMID- 4360713
TI  - Phosphatidylinositol kinase. A component of the chromaffin-granule membrane.
AB  - Phosphorylation of bovine chromaffin granules by ATP leads to the formation of
      diphosphoinositide in the granule membrane. Both phosphatidylinositol kinase and
      its substrate are components of this membrane, and triphosphoinositide is not
      formed under the conditions of the assay. The reaction is Mg(2+)-dependent and is
      stimulated by Mn(2+) and F(-) ions. The initial reaction is rapid, with a broad
      pH profile and a ;transition' temperature for its activation energy at 27 degrees
      C. The apparent K(m) for ATP is 5mum. ATP, N-ethylmaleimide, Cu(2+) ions and
      NaIO(4) are inhibitory. The phospholipids of chromaffin-granule membranes have
      been analysed: 6.8% of the lipid P is found in phosphatidylinositol, and only 2
      3% in phosphatidylserine. Comparison of the rate of phosphorylation of intact and
      lysed granules suggests that the sites for phosphorylation are on the outer
      (cytoplasmic) surface of the granules, and diphosphoinositide may therefore make
      an important contribution to the charge of the chromaffin granule in vivo.

PMID- 4360714
TI  - Stimulation of ribonucleic acid polymerase activity in vitro by prostatic steroid
      protein receptor complexes.
AB  - A system has been developed which allows the stimulation in vitro of prostatic
      RNA polymerase by prostatic 5alpha-dihydrotestosterone-protein receptor complexes
      prepared from the tissues of castrated rats. The reconstitution in vitro of such
      a system necessitates the purification of several subcellular components. Two
      5alpha-dihydrotestosterone-receptor complexes are located in the prostatic
      soluble supernatant fraction, separable by selective ammonium sulphate
      fractionation, and one complex can be isolated from the nuclear fraction. In the
      presence of all these complexes, stimulation of RNA polymerase in intact nuclei
      and nucleoli was observed. The complexes also increased the activity of the
      enzyme solubilized from whole nuclei. Greater stimulation of this system was
      noted in the presence of prostatic chromatin as template, as compared with that
      observed with calf thymus DNA or liver chromatin as template. The effects of the
      complexes on subnuclear forms of RNA polymerase, of nucleolar and extranucleolar
      origin, are also described. RNA polymerase solubilized from nucleoli is more
      susceptible to stimulation by the 5alpha-dihydrotestosterone-receptor complexes
      than is the ;nucleoplasmic' enzyme. Stimulation occurs less readily in the
      presence of Mn(2+) and at high ionic strength than in the presence of Mg(2+) and
      at low ionic strength. Preliminary experiments show that prostatic nucleolar RNA
      polymerase transcribes prostatic chromatin poorly as compared with the
      nucleoplasmic enzyme. The observations reported indicate an involvement of non
      histone proteins associated with DNA in the process by which stimulation of
      enzyme activity by the 5alpha-dihydrotestosterone-receptor complexes is achieved.
      The implications of these findings in the mechanism of steroid hormone action is
      considered.

PMID- 4360715
TI  - Synthesis and degradation of mitochondrial components in hypertrophied rat heart.
AB  - The accumulation of inner mitochondrial components of rat heart was studied 1 and
      3 days after constriction of the ascending aorta of rats. By 1 day after aortic
      constriction, the activities of three mitochondrial respiratory enzymes/mg of
      cardiac homogenate protein were increased; after 3 days, specific activities had
      levelled off or decreased. Selective accumulation of inner mitochondrial membrane
      components 24h after aortic constriction was further indicated by increased left
      ventricular cytochrome c concentration (nmol/mg of protein). By 3 days after
      surgery, cytochrome c concentration was significantly diminished. Low-temperature
      spectroscopy of isolated mitochondria showed that the ratios of cytochromes c, b
      and a+a(3) remained unchanged after aortic constriction, suggesting that
      cytochrome c was a good indicator of the response of the other mitochondrial
      inner-membrane cytochromes as well. The effect of cardiac hypertrophy on the
      turnover of cytochrome c was also examined. Cytochrome c was labelled in its haem
      group with delta-amino[2,3-(3)H(2)]laevulinate 3 days before aortic constriction.
      By 1 day after surgery the total ventricular radioactivity in cytochrome c of
      aortic banded animals was significantly higher than in sham-operated controls,
      indicating a decreased degradation rate in the former during the first
      postoperative day. delta-Aminolaevulinate was shown to be a particularly suitable
      precursor for such turnover studies, since it results in rapid pulse-labelling of
      cytochrome c (peak activity in 90min), is rapidly removed from the precursor pool
      (t((1/2))=30min) and is not reutilized.

PMID- 4360716
TI  - The degradation of L-histidine in the rat. The formation of imidazolylpyruvate,
      imidazolyl-lactate and imidazolylpropionate.
AB  - 1. Soluble and mitochondrial forms of histidine-pyruvate aminotransferase were
      separated from rat liver preparations by chromatography on DEAE-cellulose. 2.
      These enzymes were characterized with respect to substrate specificity, substrate
      affinity, pH optimum, stability and molecular weight by chromatography on
      Sephadex G-200. 3. Each enzyme has a relatively broad specificity showing
      significant activity towards l-phenylalanine and l-tyrosine and catalysing
      transamination with a number of monocarboxylic 2-oxo acids. 2-Oxoglutarate is not
      a substrate for either enzyme. 4. The molecular weights of the two enzymes, by
      chromatography on Sephadex G-200, are in the range 130000-150000. 5. The
      formation in vitro of imidazolyl-lactate from imidazolylpyruvate and NADH was
      demonstrated by using liver preparations. 6. From a study of imidazolyl-lactate
      NAD(+) oxidoreductase activity after electrophoresis of liver preparations on
      polyacrylamide gel, and from an examination of the activity of l-lactate-NAD(+)
      oxidoreductase (EC 1.1.1.27) towards imidazolylpyruvate, it is concluded that
      this latter enzyme is responsible for the formation of imidazolyl-lactate in the
      liver. 7. Preparations of bacteria obtained from rat faeces form
      imidazolylpropionate from l-histidine and urocanate without further subculture.
      The amount of imidazolylpropionate formed is increased under anaerobic conditions
      and more so in an atmosphere of H(2). It is suggested that the gut flora of the
      rat contribute largely, if not exclusively, to the formation of
      imidazolylpropionate normally found in the urine.

PMID- 4360717
TI  - Quantitative studies on ferredoxin in greening bean leaves.
AB  - Two methods of measuring small amounts of the iron-sulphur protein ferredoxin are
      described. One involves measurements of the signal at g=1.96 produced by reduced
      ferredoxin in an e.p.r. (electron-paramagnetic-resonance) spectrometer; the other
      depends on the rate of ferredoxin-dependent electron transport in a chloroplast
      bioassay measured in an O(2) electrode. These methods of measurement were used to
      examine the development of ferredoxin during the greening of etiolated bean
      leaves. Ferredoxin is present in low concentrations in the leaves and cotyledons
      of 14-day-old etiolated beans (Phaseolus vulgaris L. var. Canadian Wonder), and
      develops in a linear manner with time when the leaves are illuminated. This
      synthesis appears to be independent of chlorophyll synthesis during the early
      stages of greening. However, the chlorophyll/ferredoxin ratio reaches a final
      value of approx. 360 irrespective of the light intensity, indicating the
      existence of a control mechanism operative in deciding the stoicheiometry of
      these components in the mature chloroplast. The ferredoxin synthesis appears to
      be light-dependent, and red light is the most effective in its promotion. The
      effect of red illumination is not reversed by far-red light, indicating the
      absence of a phytochrome control of ferredoxin synthesis. From experiments using
      specific inhibitors of chloroplast protein synthesis, it is concluded that
      ferredoxin is synthesized on cytoplasmic ribosomes.

PMID- 4360719
TI  - The ultrastructure of Geotrichum candidum hyphae.

PMID- 4360718
TI  - Inhibition by ricin of protein synthesis in vitro: 60 S ribosomal subunit as the
      target of the toxin.
AB  - Poly(U)-directed polyphenylalanine synthesis by rat liver ribosomes is strongly
      inhibited by ricin. Experiments involving hybridization between subunits derived
      from normal and ricin-treated ribosomes demonstrate that the 60S subunit is the
      site of action of the toxin. The toxin inactivates the 60S subunit independently
      of the presence of the 40S subunit.

PMID- 4360720
TI  - Recent developments with the L5178Y TK heterozygote mutagen assay system.

PMID- 4360721
TI  - Use of the asparagine auxotroph of the L5178Y murine leukemia for the detection
      of chemical mutagens in vitro and in the host-mediated assay.

PMID- 4360722
TI  - Evaluation of chromosome aberration effects of chemicals on mouse germ cells.

PMID- 4360723
TI  - Current status of the host-mediated L5178Y system for detecting chemical
      mutagens.

PMID- 4360724
TI  - Chromosome aberrations as a measure of mutagenesis: comparisons in vitro and in
      vivo and in somatic and germ cells.

PMID- 4360725
TI  - Some primary considerations in the interpretation of the dominant-lethal assay.

PMID- 4360727
TI  - Estrogen target cells in the skin.

PMID- 4360726
TI  - New developments in mutagenicity screening techniques with yeast.

PMID- 4360728
TI  - Gynecologic aspects of breast disease.

PMID- 4360729
TI  - Scanning electron microscopic study of normal and molar trophoblast.

PMID- 4360730
TI  - Strategies for developing multisource funding for community mental health
      centers.

PMID- 4360731
TI  - A process to help community mental health boards plan programs and facilities.

PMID- 4360732
TI  - Cell transformation by viruses. I. Significance of virus-specific antigens
      induced by deoxyribonucleic acid-containing tumor viruses. II. Complementary
      ribonucleic acid in cells transformed by ribonucleic acid-containing tumor
      viruses.

PMID- 4360733
TI  - Biochemical aspects of viral transformation.

PMID- 4360735
TI  - Surgical correction of islet cell adenocarcinoma in a dog.

PMID- 4360736
TI  - Myomycin, a new antibiotic.

PMID- 4360734
TI  - Cell culture techniques in the search for cancer viruses of man.

PMID- 4360737
TI  - Ultrastructure of the crayfish kidney--coelomosac, labyrinth, nephridial canal.

PMID- 4360738
TI  - [Value of angiotensin in the diagnosis of kidney cancer (preliminary report)].

PMID- 4360739
TI  - Editorial: The kidney and uric acid excretion in man.

PMID- 4360740
TI  - Virology and the nonhuman primate.

PMID- 4360741
TI  - Use of nonhuman primates in virus research.

PMID- 4360743
TI  - Viral epizootics in captive nonhuman primates.

PMID- 4360742
TI  - Activities of the NIH-WHO regional reference center for simian viruses.

PMID- 4360744
TI  - Natural and experimental infections of nonhuman primates with respiratory
      viruses.

PMID- 4360745
TI  - C-type oncogenic viruses of nonhuman primates.

PMID- 4360746
TI  - Spontaneous lymphoma of the nonhuman primate.

PMID- 4360747
TI  - Virus from stumptailed monkey (Macaca arctoides) kidney cultures.

PMID- 4360748
TI  - Pathology and clinical history of Delta herpesvirus infection in patas monkeys.

PMID- 4360749
TI  - Recent studies on the isolation and characterization of Delta herpesvirus.

PMID- 4360750
TI  - Ascorbic acid (vitamin C) and its effects on parainfluenza type 3 virus infection
      in cotton-topped marmosets.

PMID- 4360751
TI  - Spontaneous neoplasms of nonhuman primates. Attempted transmission to
      immunosuppressed hosts and in vitro characterization.

PMID- 4360752
TI  - Comparative protection by polyoma virus and xenogenic polyoma-induced tumour
      cells against tumour allograft.

PMID- 4360754
TI  - The effects of circumcision on sleep-wake states in human neonates.

PMID- 4360753
TI  - Use of oral antibiotics in protected units environment: clinical effectiveness
      and role in the emergence of antibiotic-resistant strains.

PMID- 4360755
TI  - [Prognostic factors in the chemotherapy of bronchial cancers].

PMID- 4360756
TI  - Immunologic deficiency in Hodgkin's disease.

PMID- 4360757
TI  - Clinicopathology of equine rhinopneumonitis abortion in central Iowa.

PMID- 4360758
TI  - [Stimulation electromyography in tumors of the posterior regions of the cerebral
      hemispheres].

PMID- 4360759
TI  - [Toxic and sensitizing properties of pertussis monovaccines from microbes of
      different serologic types].

PMID- 4360760
TI  - Studies on nucleic acids in RSV-induced mouse ascites sarcoma cells. Base
      compositions and chromatographic behaviors.

PMID- 4360761
TI  - Adenosine 3', 5'-monophosphate-dependent protein kinase from SV 40-induced
      hamster tumor.

PMID- 4360762
TI  - Immunofluorescent and electron microscopic studies of cultured human cells
      successively transformed by Rous sarcoma virus and simian virus 40.

PMID- 4360763
TI  - Molecular forms and activities of glucose 6-phosphate dehydrogenase in cultured
      human cells.

PMID- 4360764
TI  - [New genetic concepts in manic-depressive psychosis].

PMID- 4360766
TI  - Family-based epidemiologic studies. The second Wade Hampton Frost Lecture.

PMID- 4360765
TI  - Human immunoglobulin M antibody in the sero-diagnosis of Japanese encephalitis
      virus infections.

PMID- 4360767
TI  - Evolutionary aspects of interactions between human host and virus populations.

PMID- 4360768
TI  - Epidemic of adenovirus type 7 acute conjunctivitis in swimmers.

PMID- 4360769
TI  - Enzymatic production of experimental emphysema in the dog. Route of exposure.

PMID- 4360770
TI  - Electron microscopic studies on the parafollicular cells and parafollicular cell
      complexes in the dog.

PMID- 4360771
TI  - The central nervous system, liver, and spleen of FM mice. Ultrastructural,
      histochemical, and biochemical studies.

PMID- 4360772
TI  - [Electron microscopy of adenohypophysis cells under normal conditions and after
      transplantation of tumors].

PMID- 4360773
TI  - [Experimental infection of the equine nasal mucosa with rhinopneumonitis virus
      (Herpesvirus equi 1)].

PMID- 4360774
TI  - Action of micrococcal nuclease on chemically modified deoxyribonucleic acid.

PMID- 4360775
TI  - Studies on the relationship between deoxyribonucleic acid polymerase activity and
      intracisternal A-type particles in mouse myeloma.

PMID- 4360776
TI  - Differences in in vivo methylation patterns of tyrosine and histidine transfer
      ribonucleic acids from rat liver and Novikoff hepatoma.

PMID- 4360777
TI  - Isolation and partial characterization of chimpanzee plasma high density
      lipoproteins and their apolipoproteins.

PMID- 4360778
TI  - Chemical structure of a novel glycolipid from an extreme thermophile,
      Flavobacterium thermophilum.

PMID- 4360779
TI  - A comparison of the kinetics and stoichiometry of proton uptake with aldehyde
      reduction for liver alcohol dehydrogenase under single turnover conditions.

PMID- 4360780
TI  - Frequency and temperature dependence of the proton relaxation rates of solvent
      and substrate interaction with isocitrate dehydrogenase bound Mn(II).

PMID- 4360781
TI  - Electron and nuclear magnetic resonance studies of the interaction of pyruvate
      with transcarboxylase.

PMID- 4360782
TI  - Biosynthesis of viomycin. I. Origin of alpha, beta-diaminopropionic acid and
      serine.

PMID- 4360783
TI  - Biosynthesis of viomycin. II. Origin of beta-lysine and viomycidine.

PMID- 4360784
TI  - Circular dichroism spectra of the copper enzyme, galactose oxidase, in the
      presence of its substrates and products.

PMID- 4360785
TI  - Guanidine hydrochloride and acid denaturation of horse, cow, and Candida krusei
      cytochromes c.

PMID- 4360787
TI  - [The effect of pH on the kinetics of pyrophosphate hydrolysis by baker's yeast
      inorganic pyrophosphatase].

PMID- 4360786
TI  - [Ribosephosphate isomerase, phosphoribulokinase and ribulosediphosphate
      carboxylase in extracts of Thiobacillus thiooxidans 58 R cells].

PMID- 4360788
TI  - [K+-dependent p-nitrophenylphosphatase activity of the outer segments of the
      retinal rods].

PMID- 4360789
TI  - [Electron transport and oxidative phosphorylation in reconstituted membranes].

PMID- 4360790
TI  - [Cyclic AMP].

PMID- 4360791
TI  - [Electron transport chain in the isolated nuclei and nuclear membranes of the rat
      liver].

PMID- 4360792
TI  - [Tumor lipids. Sphingomyelins of tumors and of homologous normal tissues].

PMID- 4360794
TI  - Duck hepatitis virus interactions with DDT and dieldrin in adult mallards.

PMID- 4360793
TI  - [Effect of certain inhibitors on polyphosphoinositide metabolism in brain
      homogenates].

PMID- 4360795
TI  - PPD-stimulated interferon: in vitro macrophage-lymphocyte interaction in the
      production of a mediator of cellular immunity.

PMID- 4360796
TI  - Hormonal regulation of the immune response. II. Influence of pituitary and
      adrenal activity on immune responsiveness in vitro.

PMID- 4360797
TI  - Derivative polarography of normal and cancerous tissue extracts and urines.

PMID- 4360798
TI  - Enzymatic ADP-ribosylation of proteins and regulation of cellular activity.

PMID- 4360799
TI  - Investigations on the specificity of hormone receptors in planarians.

PMID- 4360800
TI  - Structure and function of the transplanted pituitary in the seawater goby,
      Gillichthys mirabilis. I. The rostral pars distalis.

PMID- 4360802
TI  - [Treatment of herpes keratitis with human leukocyte interferon].

PMID- 4360801
TI  - Neural control of pituitary adrenal activity in Cyprinus carpio.

PMID- 4360803
TI  - Relationship of craniofacial changes and skeletal age increments in females.

PMID- 4360804
TI  - A longitudinal examination of speed of reaction and speed of movement in young
      boys 7 to 13 years.

PMID- 4360805
TI  - Hepatoblastoma: pathological studies in a case.

PMID- 4360806
TI  - The phosphorescent state of indole. Observations using optically detected
      magnetic resonance.

PMID- 4360807
TI  - Resolution of tryptophan phosphorescence from multiple sites in proteins using
      optical detection of magnetic resonance.

PMID- 4360808
TI  - Crystal structure of 1-(2-indol-3-ylethyl)-3-carbamidopyridinium chloride, an
      intramolecular model of the nicotinamide adenine dinucleotide--tryptophan charge
      transfer complex.

PMID- 4360809
TI  - Collaborative study of an on-column periodate reaction method for the analysis of
      phenylpropanolamine hydrochloride in elixirs.

PMID- 4360810
TI  - Fructose-1, 6-bisphosphatase of an extreme thermophile.

PMID- 4360812
TI  - Effect of lysolecithin and albumin on lecithin-cholesterol acyltransferase
      activity in human plasma.

PMID- 4360811
TI  - Electron and proton transport in Rhodospirillum rubrum chromatophores.

PMID- 4360813
TI  - Sparganum proliferum, a sparganum infected with a virus?

PMID- 4360814
TI  - Isospora felis: development in cultured cells with some cytological observations.

PMID- 4360815
TI  - Hemoglobin absorption in the gut of a monogenetic Trematode, Dicilidophora
      merlangi.

PMID- 4360816
TI  - Hyperlipidemia and coronary artery disease. Prinicples of diet and drug
      treatment.

PMID- 4360817
TI  - HeLa cell plasma membranes.

PMID- 4360818
TI  - Anucleate mammalian cells: applications in cell biology and virology.

PMID- 4360819
TI  - Use and misuse of steroids.

PMID- 4360820
TI  - The role of macromolecules in neuronal function in Aplysia.

PMID- 4360821
TI  - Reiter's disease: a review with special attention to cardiovascular and
      neurologic sequellae.

PMID- 4360822
TI  - [Determination of some psychopharmacological drugs by titration with silico
      wolframic acid].

PMID- 4360823
TI  - Some aspects of the penicillin V-acylase produced by Rhodotorula glutinis var.
      glutinis.

PMID- 4360824
TI  - Preparation and evaluation of ACTH antibodies.

PMID- 4360825
TI  - Arterial hypertension induced by 9 alpha-fluorocortisol in rats.

PMID- 4360826
TI  - Sex dimorphism in the adrenal of hamsters.

PMID- 4360828
TI  - [Hyperlipoproteinema in chronic arteriosclerotic vascular diseases with
      occlusions of lower extremities (author's transl)].

PMID- 4360827
TI  - Ultrastructural pathology of murine cytomegalovirus infection in cultured mouse
      nervous system tissue.
AB  - Mouse spinal cord-ganglia cultures were innoculated with murine cytomegalo-virus
      14 days after explantation. Intranuclear virus was first observed 4 days after
      infection. The viruses, which occurred in four forms, were observed in increasing
      numbers during the ensuing 4 days. Differences were noted in the relative
      prevalence of certain of these forms in older as compared to younger cultures.
      This suggests that variations in virus form are related to virus maturation.
      Cytoplasmic viruses were occasionally observed, but their site of origin is not
      certain. A variety of cytoplasmic inclusions were seen, particularly in the older
      cultures. It seems likely that they represent specific cell responses to the
      presence of the virus. They were not observed in the control cultures, even
      though some of the latter did show severe degenerative changes.

PMID- 4360829
TI  - [Some properties of individual strains of ristomycin-producing organism and
      methods of their storage].

PMID- 4360830
TI  - Chordoma-like subcutaneous nodules in an infant.

PMID- 4360831
TI  - Ultraviolet light and cytoplasmic tubules in lupus erythematosus.

PMID- 4360832
TI  - Proceedings: Cylindroma.

PMID- 4360833
TI  - The temperature dependency of cochlear adaptation and masking in the guinea pig.

PMID- 4360834
TI  - The genetics of herpesvirus.

PMID- 4360836
TI  - Light microscopic observations of transplantable mouse hepatomas.

PMID- 4360835
TI  - Nucleotide contents of ascites hepatoma cells and their changes induced by D
      galactosamine.

PMID- 4360837
TI  - A direct relationship between immune competence and the subcutaneous growth rate
      of a malignant murine lung tumor.

PMID- 4360838
TI  - Prolactin receptors in mammary carcinoma cells.

PMID- 4360839
TI  - Strain- and age-dependent transplacental carcinogenesis by 1-ethyl-1-nitrosourea
      in inbred strains of mice.

PMID- 4360840
TI  - The enzymology of methionine metabolism in rat hepatomas.

PMID- 4360841
TI  - Sites of synthesis of murine RNA tumor virus (oncornavirus) group-specific
      antigens.

PMID- 4360842
TI  - Sensitivity of transformed and nontransformed cells to amphotericin B and several
      rifamycin derivatives.

PMID- 4360843
TI  - Thioacetamide-induced alterations in nuclear RNA transport.

PMID- 4360844
TI  - Mitochondrial membrane-associated properties of Morris hepatomas.

PMID- 4360845
TI  - Studies on the relationship between infection with bovine C-type virus, leukemia,
      and persistent lymphocytosis in cattle.

PMID- 4360846
TI  - [Cyclic AMP and malignant glioma. II. Effects of cyclic AMP on the growth of
      glial tumors].

PMID- 4360847
TI  - The cryptophthalmos-syndactyly syndrome. Description, manner of inheritance, and
      notes on the eye lesions.

PMID- 4360848
TI  - Membranous conjunctivitis due to adenovirus type 7 infection.

PMID- 4360849
TI  - Schistosoma mansoni: ultrastructural observations on the small intestine of
      murine host.

PMID- 4360850
TI  - [Functional status of the fastest and slowest motor fibers of the ulnar nerve in
      progressive polyarthritis].

PMID- 4360851
TI  - [Hyperparathyroid-like syndrome associated with hepatoma].

PMID- 4360852
TI  - [The use of water-soluble estrogens in plastic surgery].

PMID- 4360853
TI  - Multidisciplinary teams develop programming for patient education.

PMID- 4360854
TI  - Ectopic ACTH production in carcinoma of the lung.
AB  - Immunoreactive ACTH was found in almost all tissue extracts of lung carcinoma
      from patients without clinical evidence of Cushing's syndrome; i.e. 14 of 15
      primary tumors, nine of nine metastatic lymph nodes, and four of four metastatic
      liver nodules contained immunoreactive ACTH. The incidence of ACTH in extracts of
      other tumor types was much lower. Comparable normal tissues contained no
      detectable ACTH. Immunoreactive growth hormone, parathyroid hormone, or gastrin
      was not found in the same carcinoma tissue. The predominant form of ACTH in the
      tumor extracts was big ACTH. In pituitary extracts little ACTH predominated.53%
      of 83 patients with lung carcinoma had afternoon plasma ACTH levels greater than
      150 pg/ml; more than 90% of plasmas containing less than 150 pg/ml were obtained
      from patients who had received radiation therapy or chemotherapy. 31% of 45
      patients with chronic obstructive pulmonary disease (COPD), 28% of 25 patients
      with other severe lung disease, and 6% of 33 controls had elevated values. Big
      ACTH predominated in the plasma of patients with lung carcinoma or COPD having
      elevated ACTH levels. Tissue from the lung of a smoking dog with atypical
      histologic changes contained immunoreactive ACTH, almost exclusively in the big
      form, while tissue from another smoking dog that was histologically normal
      contained no ACTH. Thus ACTH may be present even in precancerous lung lesions.
      These studies suggest that serial plasma ACTH levels may be of value in screening
      for, and/or management of, patients with carcinoma of the lung.

PMID- 4360855
TI  - Beta-sitosterolemia and xanthomatosis. A newly described lipid storage disease in
      two sisters.
AB  - Although the usual diet may contain 150-250 mg of plant sterols, chiefly beta
      sitosterol, only trace amounts of these sterols have heretofore been found in
      human or animal blood and tissues. We now report elevated plant sterol levels in
      the blood and tissues of two sisters with extensive tendon xanthomas but normal
      plasma cholesterol levels. Besides beta-sitosterolemia and xanthomatosis, no
      other physical, mental, or biochemical abnormalities were detected.Repeatedly,
      the plasmas of the two sisters have contained 27.1 and 17.7 mg/100 ml of beta
      sitosterol, 9.7 and 8.2 mg/100 ml of campesterol, and 0.5 and 0.5 mg/100 ml of
      stigmasterol, respectively. These plant sterols constituted 15.6 and 11.3% of the
      total plasma sterols. Some 60% of the plasma beta-sitosterol and campesterol was
      esterified; the measurable stigmasterol was entirely unesterified. The transport
      of the plasma beta-sitosterol and campesterol was largely in low density
      lipoproteins (76 and 83%, respectively). High density lipoproteins carried the
      remainder. Plant sterols were barely detectable in the very low density
      lipoprotein fraction. Only trace amounts of stigmasterol could be detected in the
      low density and high density lipoprotein fractions. The plant sterol content of
      the red blood cells averaged 12-13 mg/100 ml packed cells or about 13% of the
      total sterols. Two tendon xanthoma biopsies with the usual high concentration of
      cholesterol had 36.7 and 4.0 mg of plant sterols/g dry wt, of which 25.7 and 2.9
      mg were beta-sitosterol, entirely in the free form. Plant sterols were also found
      in adipose tissue (0.2 mg/g wet wt) and in skin surface lipids (3.2 mg/g of
      lipid). The intestinal absorption of beta-sitosterol in both the patients,
      measured by two techniques, indicated greatly increased absorption of this sterol
      (about 24 and 28% in the patients L. H. and R. H., respectively, normal
      absorption being <5%). We suggest that increased absorption of beta-sitosterol
      must be considered as one cause of this disease. The reason for the extensive
      xanthomatosis in these two patients remains unknown. Perhaps in some way plant
      sterols initiated the development of xanthomas with otherwise normal plasma
      cholesterol levels. Clinical atherosclerosis has not yet occurred. The occurrence
      of beta-sitosterolemia in these two sisters with un-affected parents suggests an
      inherited recessive trait.

PMID- 4360856
TI  - On the mechanism of lithium-induced diabetes insipidus in man and the rat.
AB  - The mechanism of lithium-induced diabetes insipidus was investigated in 96
      patients and in a rat model. Polydipsia was reported by 40% and polyuria (more
      than 3 liter/day) by 12% of patients receiving lithium. Maximum concentrating
      ability after dehydration and vasopressin was markedly impaired in 10 polyuric
      patients and was reduced in 7 of 10 nonpolyuric patients studied before and
      during lithium therapy. Severe polyuria (more than 6 liter/day) was unresponsive
      to trials of vasopressin and chlorpropamide, but improved on chlorothiazide. Rats
      receiving lithium (3-4 meq/kg/day) developed massive polyuria that was resistant
      to vasopressin, in comparison to rats with comparable polyuria induced by
      drinking glucose. Analysis of renal tissue in rats with lithium polyuria showed
      progressive increase in the concentration of lithium from cortex to papilla with
      a 2.9-fold corticopapillary gradient for lithium. The normal corticopapillary
      gradient for sodium was not reduced by lithium treatment. The polyuria was not
      interrupted by brief intravenous doses of vasopressin (5-10 mU/kg) or dibutyryl
      cyclic AMP (10-15 mg/kg) capable of reversing water diuresis in normal and
      hypothalamic diabetes insipidus rats (Brattleboro strain). The present studies
      suggest that nephrogenic diabetes insipidus is a common finding after lithium
      treatment and results in part from interference with the mediation of vasopressin
      at a step distal to the formation of 3',5' cyclic AMP.

PMID- 4360857
TI  - The mechanism of activation of hormone-sensitive lipase in human adipose tissue.
AB  - A partially purified hormone-sensitive triglyceride lipase of human adipose
      tissue was found to be activated twofold by the addition of cyclic 3',5'-AMP,
      ATP, and magnesium ions. Lipase activities against diolein and monoolein were not
      affected. Addition of protein kinase inhibitor at zero time completely inhibited
      activation, and this inhibition was prevented by prior addition of an excess of
      exogenous protein kinase (from rabbit skeletal muscle). Addition of protein
      kinase inhibitor during the activation step blocked the activation process
      without a time lag, suggesting that protein kinase operates directly on hormone
      sensitive lipase. Further purification yielded a fraction free of protein kinase,
      and lipase activation in this fraction depended absolutely on addition of
      exogenous kinase. Incubation of human fat with epinephrine or isoproterenol
      stimulated lipolysis and caused conversion of nonactivated hormone-sensitive
      lipase to its activated form, as indicated by a decrease in the activation
      subsequently obtainable in fractions prepared from such hormone-treated tissues.
      These findings strongly suggest that the stimulation of lipolysis by hormonal
      treatment is the consequence of the activation of hormone-sensitive triglyceride
      lipase by cyclic 3',5'-AMP-dependent protein kinase.

PMID- 4360859
TI  - A specific role for saline or the sodium ion in the regulation of renin and
      aldosterone secretion.
AB  - It is well established that in normal man the renin-angiotensin-aldosterone
      system is responsive to changes in volume. The present study was performed to
      determine whether sodium has an action apart from volume in the regulation of the
      secretion of renin and aldosterone. Acute volume expansion was induced either by
      saline, dextran, or glucose infusion in supine, normal subjects in balance on a
      10 meq sodium/100 meq potassium diet. Plasma renin activity (PRA), angiotensin II
      (A II), aldosterone (PA), cortisol, serum sodium, and potassium were measured
      every 10 min for the first 30 min and then at 1, 2, 4, 6, and 8 h. During saline
      infusion (500 cm(3)/h for 6 h) mean PRA and A II levels declined very rapidly,
      falling significantly below control at 10 min (P < 0.01) and by 50% at 60 min.
      Thereafter, the rate of fall was more gradual, reaching a nadir at 360 min (70
      80% below control). PA declined in a parallel pattern except that a significant
      fall did not occur until 30 min. In contrast to saline, dextran infusion (250
      cm(3)/h for 4 h) did not produce a significant fall in PRA, A II, or PA until 4 h
      after the start of the infusion despite equivalent volume expansion. On the other
      hand, the infusion of 5% glucose and water (500 cm(3)/h for 6 h) did not produce
      a significant decline in PRA, A II, or PA over the first 6 h of the study.
      Although the response rate of PRA, A II, and PA was different in each of the
      three infusion studies, these parameters were significantly correlated within
      each study. Serum sodium and potassium levels did not change during any study
      except dextran infusion, where a significant fall in both occurred at 120 min. In
      all the infusion studies, plasma cortisol levels gradually declined during the 8
      h study period consistent with its expected rhythm of diurnal secretion. These
      results demonstrate that rate of response of the renin-angiotensin-aldosterone
      system to acute volume expansion with saline differed from that with dextran and
      glucose infusion in sodium-depleted man. The data support a specific role for
      volume expansion with saline or the sodium ion per se in the regulation of renin
      and aldosterone.

PMID- 4360858
TI  - Sequence of events mediating the effect of cholera toxin on rat thymocytes.
AB  - We have found that in rat thymocytes binding of [(125)I]choleragen is followed by
      cellular accumulation of cyclic 3',5'-AMP which, in turn, is followed by
      stimulation of amino acid transport. Binding of cholera toxin was complete by 30
      min and remained constant for the subsequent 150 min. After stimulation by
      choleragen, cellular cyclic 3',5'-AMP became maximal by 30 min, after which it
      declined steadily so that by 90 min of incubation, cellular cyclic nucleotide
      levels were only 20% of those seen at 30 min. Stimulation of amino acid
      transport, although detectable by 15 min, did not become maximal until 120 min
      (by which time cellular cyclic 3',5'-AMP had decreased by more than 80%). We have
      also used this system to delineate the step at which various pharmacologic agents
      and hormones act to alter the sequence of events mediating the response of rat
      thymocytes to cholera toxin. The ability of cycloheximide to abolish choleragen
      stimulated amino acid influx without reducing [(125)I]choleragen binding or
      cellular cyclic 3',5'-AMP suggests that cyclic nucleotide stimulation of amino
      acid transport includes a step involving protein synthesis.

PMID- 4360860
TI  - Studies on the effect of specific antisera on the metabolism of cellular
      antigens. II. The synthesis and degradation of TL antigens of mouse cells in the
      presence of TL antiserum.

PMID- 4360861
TI  - Genetic control of the immune response: the effect of non-H-2 linked genes on
      antibody production.

PMID- 4360862
TI  - Comparative in vitro studies on effector cell diversity in the cellular immune
      response to murine sarcoma virus (MSV)-induced tumors in mice.

PMID- 4360863
TI  - The characteristics of a circulating antigen in schistosomiasis.

PMID- 4360864
TI  - Cancer and ectopic hormones.

PMID- 4360866
TI  - Provocative tests of the hypothalamic-anterior pituitary-target organ axis.

PMID- 4360867
TI  - The enterohormones. Current status and review.

PMID- 4360868
TI  - Biochemistry of cancer cells: focus on the cell surface.

PMID- 4360865
TI  - Metabolic bone disease--recent developments.

PMID- 4360869
TI  - [The importance of cyclic adenosine monophosphate in growth regulation].

PMID- 4360870
TI  - [Letter: Paget's disease and Ovestin].

PMID- 4360871
TI  - [Treatment of 11 nasopharyngeal angiofibromas].

PMID- 4360872
TI  - Toxoplasmosis: a review.

PMID- 4360873
TI  - [Histoenzymology of the lutein and interstitial tissues of the ovaries of golden
      hamsters during the sexual cycle].

PMID- 4360874
TI  - Nucleus gracilis responses to knee joint motion: a frequency response study.

PMID- 4360876
TI  - Presynaptic depolarization and extracellular potassium in the cat lateral
      geniculate nucleus.

PMID- 4360875
TI  - Statistical properties of neurons in the rat mesencephalic reticular formation.

PMID- 4360877
TI  - Hippocampal suppression of intralaminar thalamic unit responses in cats and
      comparison with suppression evoked from the caudate nucleus.

PMID- 4360878
TI  - Reward-associated inhibition and pain-associated excitation lasting seconds in
      single intralaminar thalamic units.

PMID- 4360879
TI  - [Effects of lesions of the ventral mesencephalic tegmentum on switch-off
      responses in the medial hypothalamus (author's transl)].

PMID- 4360880
TI  - Dissecting a short-term memory circuit in the rat brain. I. Changes in entorhinal
      unit activity and responsiveness of hippocampal units in the process of classical
      conditioning.

PMID- 4360881
TI  - Discharge characteristics of neurons in anteroventral and dorsal cochlear nuclei
      of cat.

PMID- 4360882
TI  - Repetitive discharge rate of a simple neuron model with accumulation of after
      hyperpolarization conductance.

PMID- 4360883
TI  - Spontaneous activity of single neurons in the precruciate area of the cat's
      sensory motor cortex.

PMID- 4360884
TI  - Effects of excitants on neurones and cerebellar-evoked field potentials in the
      inferior olivary complex of the rat.

PMID- 4360885
TI  - Responses of spinal cord neurons to graded noxious and non-noxious stimuli.

PMID- 4360886
TI  - Correlation of latency to drink and unit activity following cholinergic
      stimulation of medial septal nucleus in rats.

PMID- 4360887
TI  - Projection of tooth pulp afferents in the brain stem of rhesus monkey.

PMID- 4360888
TI  - Distribution of carotid body chemoreceptor afferents in the medulla of the cat.

PMID- 4360889
TI  - Caudate-evoked inhibition and actions of GABA and other substances on cat
      pallidal neurons.

PMID- 4360890
TI  - Depression by p-methoxyphenylethylamine of sympathetic reflex firing elicited by
      electrical stimulation of the carotid sinus nerve or pelvic nerve.

PMID- 4360891
TI  - The effect of intracochlearly administered acetylcholine-blocking agents on the
      efferent synapses of the cochlea.

PMID- 4360893
TI  - Somatosensory properties of neurons in the superior parietal cortex (area 5) of
      the rhesus monkey.

PMID- 4360892
TI  - Visual and somatosensory receptive fields of neurons in the squirrel monkey
      pulvinar.

PMID- 4360894
TI  - Effect of gamma rays and some chemical mutagens on induction of telotrisomics in
      Hordeum.

PMID- 4360895
TI  - The repair of methyl methanesulphonate-induced lesions in the DNA of a murine
      lymphoma cell.

PMID- 4360896
TI  - Separation and characterization of polypeptides from the venom of Dendroaspis
      viridis.

PMID- 4360897
TI  - [Glutamate dehydrogenase. Characterization and thermodynamic studies on the
      various complexes formed with coenzymes and substrates: role of the effective
      substances ADP and GTP].

PMID- 4360898
TI  - Hormonal regulation of cyclic-AMP-dependent protein kinase of rat diaphragm by
      epinephrine and insulin.

PMID- 4360899
TI  - Thiophosphate-analogues and 1-N-oxides of ATP and ADP in mitochondrial
      translocation and phosphoryl-transfer reactions.

PMID- 4360900
TI  - Correlations between structure and spectroscopic properties in membrane model
      system. Fluorescence and circular dichroism of the cytochrome c-cardiolipin
      system.

PMID- 4360902
TI  - Studies of glutamate dehydrogenase. The interaction of glutamate dehydrogenase
      with alpha-NADH.

PMID- 4360901
TI  - Preparation of the enzymatically active subfragment of myosin by proteolysis of
      myofibrils.

PMID- 4360903
TI  - [Regulation of the cyclic AMP metabolizing enzymes of embryonic fibroblasts of
      rats by calcium ions].

PMID- 4360904
TI  - Subunit structure of aspartokinase 3 of Escherichia coli K12.

PMID- 4360905
TI  - Studies on thymus products. VI. The effects of cyclic nucleotides and
      prostaglandins on rosette-forming cells. Interactions with thymic factor.

PMID- 4360906
TI  - Cyclic AMP-mediated stimulation by calcium of thymocyte proliferation.

PMID- 4360907
TI  - Control of DNA replication in Physarum polycephalum. I. Specific activity of NAD
      pyrophosphorylase in isolated nuclei during the cell cycle.

PMID- 4360909
TI  - Mutant human fibroblast clones able to grow on homocysteine instead of
      cyst(e)ine.

PMID- 4360908
TI  - Depression of RNA synthesis in the prematurely condensed chromatin of pulverized
      HeLa cells.

PMID- 4360910
TI  - Immune microfluorimetric analysis of the distribution of species specific nuclear
      antigens in HeLa-chick erythrocyte heterokaryons.

PMID- 4360911
TI  - Radiation-induced DNA synthesis in nuclei of hen erythrocytes reactivated in
      heterokaryons.

PMID- 4360912
TI  - Comparative activities of mammalian, reptilian, and piscine gonadotropins in
      monkey granulosa cell cultures.

PMID- 4360913
TI  - Ovarian maintenance in the hypophysectomized catfish, Heteropneustes fossilis
      (Bloch), with mammalian hypophyseal and placental hormones, and gonadal and
      adrenocortical steroids.

PMID- 4360914
TI  - The control of adrenocortical secretion in the brush-tailed possum, Trichosurus
      vulpecula.

PMID- 4360915
TI  - Sleep induced by spinal cord cholinergic stimulation.

PMID- 4360916
TI  - Ascorbate oxidase. New method of purification of the enzyme from green zucchini
      squash and identity of its copper moiety with that of cucumber ascorbate oxidase.

PMID- 4360917
TI  - Remission of acanthosis nigricans associated with polycystic ovarian disease and
      a stromal luteoma.

PMID- 4360918
TI  - Secretion and metabolic efficacy of parthyroid hormone in patients with severe
      hypomagnesemia.

PMID- 4360919
TI  - Steroid production from plasma cholesterol. II. In vivo conversion of plasma
      cholesterol to ovarian progesterone and adrenal C19 and C21 steroids in humans.

PMID- 4360920
TI  - Integrated concentrations of growth hormone correlated with stage of puberty and
      estrogen levels in girls.

PMID- 4360921
TI  - Uptake of iodinated human chorionic gonadotropin by monkey ovaries in vivo.

PMID- 4360922
TI  - Pregnenolone in man: plasma levels in states of normal and abnormal
      steroidogenesis.

PMID- 4360923
TI  - Protection by pregnancy. Zollinger-Ellison syndrome.

PMID- 4360925
TI  - Local vesicle populations in rat superior cervical ganglia and the vesicle
      hypothesis.

PMID- 4360924
TI  - The relationship between ATP and an electrogenic pump in the plasma membrane of
      Neurospora crassa.

PMID- 4360926
TI  - Extracellular current density analysis of responses in cerebellar cortex to
      climbing fiber activation.

PMID- 4360927
TI  - Evidence that cyclic AMP is not the chemical mediator of the metabolic changes
      accompanying phagocytosis.

PMID- 4360929
TI  - Some inferences from galactokinase deficiency.

PMID- 4360928
TI  - The pathogenesis of anuria following shock.

PMID- 4360930
TI  - Galactokinase deficiency in twins: clinical and biochemical studies.

PMID- 4360931
TI  - Infectious mononucleosis and Epstein-Barr virus in childhood.

PMID- 4360932
TI  - "Typus Edinburgensis"?

PMID- 4360933
TI  - The influence of N6-2'-O-dibutyryl cyclic 3',5'-AMP on the metabolism of
      cholesterol-26-14C and cholesterol-4-14C in the rats fed on atherogenic or lipid
      rich diet.

PMID- 4360934
TI  - Multiple activities of DNA polymerase from visna virus.

PMID- 4360935
TI  - The association of herpesvirus type 2 infection and cervical cancer.

PMID- 4360936
TI  - Genetic economy of polyoma virus: capsid proteins are cleavage products of same
      viral gene.
AB  - Two-dimensional tryptic peptide maps of the nonhistone proteins of purified
      polyoma virus show marked similarities. Protein P(1) is a nondisaggregated,
      possibly covalent, dimer of the major capsid protein P(2), whereas P(3) and P(4)
      share several new peptides as well as many of the peptides derived from P(2).
      Extensive use of this kind of processing of viral proteins during the
      biosynthesis of DNA-containing animal viruses has not been reported previously.

PMID- 4360937
TI  - Absence of a specific ganglioside galactosyltransferase in mouse cells
      transformed by murine sarcoma virus.
AB  - The ganglioside composition of a nonproducer subclone (derived from BALB/c 3T3
      mouseembryo cells) transformed by Kirsten murine sarcoma virus was drastically
      altered compared to the nontransformed parental clone. The transformed clone was
      unable to synthesize the mono- and disialogangliosides, G(M1) and G(D1a), due to
      the complete absence of a specific galactosyltransferase. The lack of this enzyme
      activity was established by sensitive radiochemical and enzymological techniques
      in vivo and in vitro.

PMID- 4360938
TI  - Cell-free translation of messenger RNA of simian virus 40: synthesis of the major
      capsid protein.
AB  - Extracts of wheat germ are capable of synthesizing the major capsid protein of
      simian virus 40. Poly(A)-containing RNA from BS-C-1 cells infected with simian
      virus 40 directed the synthesis of a novel polypeptide that migrates in
      polyacrylamide gels together with the major capsid polypeptide of simian virus
      40, VP-1. The patterns of the major tryptic peptides of purified VP-1 and the
      novel polypeptide synthesized in vitro were identical after two-dimensional paper
      electrophoresis. The novel polypeptide was not synthesized in response to poly(A)
      rich RNA from uninfected cells or from virus-infected cells treated with cytosine
      arabinoside. Messenger RNA from infected cells purified by selective
      hybridization to DNA of simian virus 40 directs the synthesis of a major
      polypeptide of electrophoretic mobility similar to that of VP-1 of simian virus
      40. This approach should prove useful in identifying additional products
      specified by DNA tumor viruses.

PMID- 4360939
TI  - Specific binding of cholera toxin to isolated intestinal microvillous membranes.
AB  - A sucrose density gradient assay was used to demonstrate the specificity and
      saturation of the binding of [(125)I]cholera toxin to isolated intestinal
      microvillous membranes from rat small intestine. When the toxin is first
      complexed to antitoxin and then exposed to intestinal membranes, the binding of
      cholera toxin is inhibited. To emphasize the physiologic importance of these
      observations, similar concentrations of [(125)I]cholera toxin were shown to
      stimulate the accumulation of cyclic AMP in mucosal homogenates and to increase
      the secretion of fluid into intestinal loops, whereas the same concentrations of
      toxin mixed with antitoxin had no effect on cyclic AMP accumulation. These
      studies suggest that cholera toxin attaches to brush border binding sites before
      exerting its biologic effect and that local intestinal antibody protection
      against cholera toxin may be due to inhibition of toxin attachment to these
      binding sites.

PMID- 4360940
TI  - Inhibition of induced aldosterone biosynthesis with a specific antagonist of
      angiotensin II.
AB  - The present study determined the effect of [Sar(1)-Ile(8)]-angiotensin II on
      steroidogenesis and induced aldosterone synthesis by the octapeptide angiotensin
      II, the heptapeptide des-Asp(1)-angiotensin II, and adrenocorticotropic hormone.
      Rabbit adrenal cells were suspended by incubation of the capsular cortical tissue
      with collagenase, and aldosterone levels were determined by immunoassay.
      Steroidogenic responses to angiotensin II and des-Asp(1)-angiotensin were
      essentially the same. [Sar(1)-Ile(8)]-angiotensin II (10(-7) to 5 x 10(-7) M) had
      no significant effect on basal aldosterone biosynthesis. However, when added with
      steroidogenic peptides, it completely blocked the effect of angiotensin II and
      des-Asp(1)-angiotensin II but not of adrenocorticotropic hormone. The dose ratio
      of the antagonist to angiotensin II that gave 100% inhibition was about 2:1 and
      to des-Asp(1)-angiotensin II, about 50:1. The data suggest that des-Asp(1)
      angiotensin II has a much higher affinity for the angiotensin receptor in adrenal
      cortex than angiotensin II.

PMID- 4360941
TI  - Homology between Burkitt herpes viral DNA and DNA in continuous lymphoblastoid
      cells from patients with infectious mononucleosis.
AB  - At least 90% of the sequences of purified, in vitro labeled, DNA from Epstein
      Barr virus (prepared from HR-1, Burkitt's lymphoblastoid cells) are homologous to
      the DNA of the herpes virus contained in cell lines derived from patients with
      infectious mononucleosis. The thermal stability of the homologous and
      heterologous hybrid DNA molecules could not be differentiated, indicating at
      least 97% matching of base pairs between DNA of Epstein-Barr virus and the herpes
      viral DNA contained in the lymphoblasts from patients with infectious
      mononucleosis.

PMID- 4360942
TI  - Nucleotide sequences of RNA transcribed in infected cells and by Escherichia coli
      RNA polymerase from a segment of simian virus 40 DNA.
AB  - The nucleotide sequence of 180 residues of an RNA transcript of DNA of simian
      virus 40 has been deduced. This sequence adjoins a preferred initiation site for
      E. coli RNA polymerase. Comparison of this sequence with that of complementary
      RNA of simian virus 40 from infected cells has shown that this site also adjoins
      the apparent 3' terminus of some of the cytoplasmic complementary RNA of simian
      virus 40.

PMID- 4360944
TI  - Translational diffusion coefficient and partition coefficient of a spin-labeled
      solute in lecithin bilayer membranes.
AB  - The translational diffusion coefficient and the partition coefficient of a spin
      labeled solute, di-t-butyl nitroxide, in an aqueous suspension of dipalmitoyl
      lecithin vesicles have been studied by electron spin resonance spectroscopy. When
      the lecithin is cooled through its phase transition temperature near 41 degrees
      C, some solute is "frozen out" of the bilayer, and the standard partial molar
      enthalpy and entropy of partition go more positive by a factor of 8 and 6,
      respectively. However, the apparent diffusion constant in the lecithin phase is
      only slightly smaller than that in water, both above and below the transition
      temperature. The fraction of bilayer volume within which solute is distributed
      may increase with temperature, contributing to the positive enthalpy of
      partition. Comparison of time constants suggests that there is a permeability
      barrier to this solute in the periphery of the bilayer.

PMID- 4360943
TI  - Initiation characteristics for the synthesis of five T4 phage-specific messenger
      RNAs in vitro.
AB  - The involvement of the nucleoside triphosphates in the initiation of the
      synthesis of the messenger ribonucleic acid of five T4 specific enzymes has been
      studied. Only one of these, the messenger RNA for deoxynucleosidemonophosphate
      kinase, can be initiated in the presence of one nucleoside triphosphate, namely
      ATP. All of the remaining four require the presence of at least two nucleoside
      triphosphates during the initiation period. The combination of ATP and UTP was
      best for the initiation of messenger RNA for dihydrofolate reductase, ATP and CTP
      for deoxycytidylate hydroxymethyltransferase and beta-glucosyltransferase, and
      ATP and GTP for alpha-glucosyltransferase. We have concluded that there is a
      great variation in the nucleotide composition and sequence of the initiation
      sites in T4 DNA. No correlation in the requirements of nucleoside triphosphates
      during the initiation period could be observed among the five systems studied
      according to their classification as one type or another of "early" T4 messenger
      RNA.

PMID- 4360945
TI  - The effect of light on fruiting body formation and adenosine 3':5'-cyclic
      monophosphate metabolism in Coprinus macrorhizus.
AB  - The monokaryotic mycelia of a mutant strain, fis(c), of Coprinus macrorhizus,
      which are able to form monokaryotic fruiting bodies in the light, failed to form
      any fruiting bodies in darkness. A dikaryon and a mutant strain, ds, formed
      malformed fruiting bodies in darkness. Illumination for 1 day of fis(c) mycelia
      grown in darkness for 4 days or longer was effective in inducing malformed
      fruiting bodies. The accumulation of adenosine 3':5'-cyclic monophosphate in the
      illuminated mycelia of strain fis(c) was demonstrated. The illuminated mycelia of
      strain fis(c) produced high levels of adenylate cyclase [ATP pyrophosphate-lyase
      (cyclizing), EC 4.6.1.1] and phosphodiesterase (3':5'-cyclic-AMP 5'
      nucleotidohydrolase, EC 3.1.4.17), which degrades cAMP, while the dark-grown
      mycelia showed no or very low activities of these enzymes. Dikaryotic mycelia and
      monokaryotic mycelia of strain ds produced significant amounts of these enzymes
      even in darkness. When the dark-grown mycelia of strain fis(c) were exposed to
      continuous light, the activities of adenylate cyclase and phosphodiesterase
      increased rapidly after a lag period whose length depends on the culture age of
      mycelia. Cycloheximide inhibited the increase in these enzyme activities
      stimulated by light. When the fis(c) mycelia were exposed to continuous light, an
      increase in cAMP-binding activity was observed. A possible participation of cAMP
      in the formation of fruiting bodies in C. macrorhizus is discussed.

PMID- 4360946
TI  - A comparison of membrane proteins of normal and transformed cells by
      lactoperoxidase labeling.
AB  - The enzyme lactoperoxidase (iodide:hydrogen-peroxide oxidoreductase, EC 1.11.1.8)
      was used to iodinate ((125)I) accessible proteins on membranes of intact virally
      transformed and untransformed cells. A number of labeled bands of proteins were
      detected by acrylamide gel electrophoresis. A heavily labeled band with a
      molecular weight of approximately 250,000 daltons was found in all untransformed
      cells but was absent from transformed cells. When Coomassie-blue-stained membrane
      preparations were compared, a band was seen in normal cells which co-migrated
      with the lactoperoxidase-labeled band. In transformed cell membranes, three
      discrete bands were present in the same position. Thus, the expression of this
      protein may be altered when cells are in the transformed state.

PMID- 4360947
TI  - Multiple regulation of the galactose operon-genetic evidence for a distinct site
      in the galactose operon that responds to capR gene regulation in Escherichia coli
      K-12.
AB  - Previous results demonstrated that the capR (lon) locus, which is not linked to
      the gal operon, independently controls the synthesis of the gal operon enzymes
      and gal mRNA, i.e., galO(+)capR9 strains are derepressed 4- to 6-fold as compared
      to galO(+)capR(+) strains. A mutation has been isolated and localized in the
      galactose operator region that defines a new and distinct site of control.
      Mutation in this site, designated galO(capR+), causes a 4-fold increase in the
      galactose enzymes, galactokinase (EC 2.7.1.6) and UDP-galactose-4-epimerase (EC
      5.1.3.2), in a capR(+) background. These mutants exhibit a reduced response to
      regulation by the unlinked regulator gene capR (lon). However, the galO(capR+)
      mutants are still subject to control by the galR repressor, since they can be
      further derepressed by growth in the presence of D-fucose. They also synthesize
      more galactokinase when grown in glycerol as compared to glucose. Thus there are
      now at least three, and probably four, sites for control of mRNA synthesis in the
      operator-promoter regions of the gal operon, making it one of the most complex
      control systems to date for a single operon in bacteria. The complexity is
      sufficient to accommodate models for differentiation in higher organisms that
      require more than one "switch" to control a single group of genes.

PMID- 4360948
TI  - Homeoviscous adaptation--a homeostatic process that regulates the viscosity of
      membrane lipids in Escherichia coli.
AB  - E. coli incorporates increasing proportions of saturated and long-chain fatty
      acids into phospholipids as growth temperature is increased. It was found that
      this compositional variation results in the biosynthesis of phospholipids that
      have identical viscosities at the temperature of growth of the cells. This
      "homeoviscous adaptation" can also be observed in E. coli membrane preparations.
      Viscosities were determined by use of the electron spin resonance spin-label
      technique.

PMID- 4360949
TI  - 31P nuclear magnetic resonance spectroscopy of native and recombined
      lipoproteins.
AB  - Native and recombined lipoproteins have been studied by (31)P nuclear magnetic
      resonance spectroscopy. Very low-, low-, and high-density lipoproteins exhibited
      characteristic spectra. The main resonances were assigned to phosphatidylcholine
      and sphingomyelin. Relaxation times for these phospholipids were separately
      measured in low-density lipoproteins and high-density lipoproteins. The effect of
      paramagnetic ions (Eu(+++)) on the nuclear magnetic resonance spectrum of high
      density lipoproteins is reported.

PMID- 4360950
TI  - Effect of prostaglandins and epinephrine on the level of cyclic AMP-14C of smooth
      muscle from the rhesus monkey.

PMID- 4360951
TI  - Prostaglandin F2 alpha concentration in genital tract secretions of dairy bulls.

PMID- 4360952
TI  - Prostaglandin E2 and its antagonists: effects on autonomic transmission in the
      isolated sino-atrial node.

PMID- 4360954
TI  - Enzyme polymorphism and metabolism.

PMID- 4360955
TI  - Prolactin receptors in estrogen receptor-deficient mammary carcinoma.
AB  - We demonstrate for the first time the presence of specific high-affinity
      receptors for prolactin in rat mammayy carcinoma. There appear to be no
      significant differences between normal rat mammary tissue and the transplantable,
      estrogen receptor-deficient R3230AC tumor with regard to the number of binding
      sites, the affinity of the receptor for prolactin, or the specificity of binding.

PMID- 4360953
TI  - Mechanism of action of lithium salts. Biochemical aspects.

PMID- 4360956
TI  - [Acute inflammatory diseases of the otorhinolaryngological organs in children
      with respiratory infections].

PMID- 4360957
TI  - [Endocrine pathogenesis of angiofibroma of the base of the skull].

PMID- 4360958
TI  - Functional aspects of dermo-epidermal junction.

PMID- 4360959
TI  - The role of macrophages in the development of contact sensitivity.

PMID- 4360960
TI  - Odland body and intercellular substances.

PMID- 4360961
TI  - Deoxyribonuclease in the cow snout epidermis.

PMID- 4360962
TI  - The particulate origin of adenylate kinase isozyme 4.

PMID- 4360963
TI  - The role of the renal medulla in hypertension.

PMID- 4360964
TI  - [Effect of pentoxyl on the intrauterine development of rats].

PMID- 4360965
TI  - [Benign angiofibroxanthoma of the skin].

PMID- 4360967
TI  - [Epidermoid metaplasia in breast tumors].

PMID- 4360966
TI  - [Histoenzymatic properties of human melanoma cells].

PMID- 4360968
TI  - [Cytologic diagnosis of different variants of angiofibroxanthoma].

PMID- 4360969
TI  - [Serous acinocellular salivary gland tumors].

PMID- 4360970
TI  - [The combined effect of inhibitors with regard to their coenzyme on yeast
      glyceraldehyde-3-phosphate dehydrogenase].

PMID- 4360971
TI  - [A study of rapid oxygen utilization by mitochondria introduced to an aerobic
      incubation medium].

PMID- 4360973
TI  - [The role of magnesium ions in hydrolysis of pyrophosphate by yeast inorganic
      pyrophosphatase].

PMID- 4360972
TI  - [Oxidative phosphorylation and ATPase activity of isolated nuclei and nuclear
      membranes of rat brain neurons and glia].

PMID- 4360974
TI  - [The phospholipid composition of mitochondria and microsomes of regenerating rat
      liver].

PMID- 4360975
TI  - [Human placenta mitochondrial glutamate dehydrogenase. A comparative kinetic
      study].

PMID- 4360976
TI  - [The effect of cyclic 3',5'-adenosine monophosphoric acid on release of Na and K
      from the external segments of retinal rods].

PMID- 4360977
TI  - [Uridine-cytidine kinase isoenzymes of rat sarcoma M-1].

PMID- 4360978
TI  - [Varying rate of destruction of alkylated molecules of RNA, protein and lipids in
      normal and neoplastic cells].

PMID- 4360979
TI  - [Spinal pathways of cortical influences on rat lumbar motoneurons].

PMID- 4360980
TI  - Virulence of indigenous strains of Entamoeba histolytica in experimental
      amoebiasis of rats.

PMID- 4360981
TI  - Studies on the effect of lowered temperature on Entamoeba histolytica strains, as
      a trial to isolate a strain of the "Laredo" type.

PMID- 4360982
TI  - Planning a community mental health program: a case history.

PMID- 4360983
TI  - Development of globule leucocyte specific granules from lysosomes.

PMID- 4360984
TI  - [The X-ray Act of March 1, 1973].

PMID- 4360985
TI  - [The value and limitations of hepatic arteriography (author's transl)].

PMID- 4360986
TI  - [Intravenous serial perfusion scintigraphy in peripheral occlusions (author's
      transl)].

PMID- 4360987
TI  - [Bacterial contamination during catheter angiography (author's transl)].

PMID- 4360989
TI  - [Investigations on the bone uptake of 99mTc-pyrophosphate, 99mTc-poly-phosphate
      and radio-strontium (author's transl)].

PMID- 4360988
TI  - [Bone scanning with 99m-Tc-polyphosphate and strontium isotopes (author's
      transl)].

PMID- 4360990
TI  - [The use of 67Ga citrate in the diagnosis of tumours of the chest (author's
      transl)].

PMID- 4360991
TI  - [Inadequate demonstration of the calyces--a disadvantage of infusion urography.
      2. A comparison between infusion urography and urography using a double dose of
      contrast (author's transl)].

PMID- 4360992
TI  - [The tip-over kidney (author's transl)].

PMID- 4360993
TI  - [Recent findings from measurements of renal plasma flow using radio-active
      Hippuran (author's transl)].

PMID- 4360994
TI  - [The recognition of compensatory hyperplasia of the kidney on isotope nephrograms
      following unilateral ligation of the ureter in animal experiements (author's
      transl)].

PMID- 4360995
TI  - [Tomography in the diagnosis of chronic caisson osteoarthropathy (author's
      transl)].

PMID- 4360996
TI  - [Benign osteo-blastoma. Rare localisation in the maxilla (author's transl)].

PMID- 4360997
TI  - [Comparison of cerebral toxicity of iothalamate and dimer Bjork in the dog
      (author's transl)].

PMID- 4360998
TI  - [Discussion comment on the paper "Extended congenital esophageal stenosis",
      Fortschr. Rontgens 117 (1972) 93 by H. Br. Makoski and U. Manfeld].

PMID- 4360999
TI  - [Multiple abnormalities of the neck spine and cervicocephalic junction].

PMID- 4361000
TI  - [Ventral rudiment of occipital vertebra associated with assimilation of a
      terminal ossiculum with the anterior atlas arch].

PMID- 4361001
TI  - [The "nasal cycle" in frontal tomography of the face skull].

PMID- 4361002
TI  - [A rare variation of branching from the aortic arch: truncus bicaroticus and
      common sublavian artery].

PMID- 4361003
TI  - [Orifice of the left deferent duct into the urinary bladder].

PMID- 4361004
TI  - Ultrastructural study of a case of extramammary Paget's disease with special
      reference to cellular changes in melanocytes and a Langerhans cell.

PMID- 4361006
TI  - [Radiological study of tympanojugular glomus tumors].

PMID- 4361007
TI  - Special observations in skeletal identification.

PMID- 4361008
TI  - [The activity of the enzyme galactokinase in the erythrocytes of healthy children
      and adults (author's transl)].

PMID- 4361009
TI  - [Paraneoplastic hyperthyroidism].

PMID- 4361011
TI  - [Neurologic problems of the old age].

PMID- 4361010
TI  - The effect of dibutyryl 3'5'-cyclic AMP on the cardiac pacemaker, arrested with
      reserpine and alpha-methyl-tyrosine.

PMID- 4361012
TI  - Role of the medial zone of the medulla in rhythmic activity of respiratory center
      neurons.

PMID- 4361013
TI  - Medical management of idiopathic facial (Bell's) palsy.

PMID- 4361014
TI  - Prostaglandins, cyclic nucleotides and cell function.

PMID- 4361015
TI  - [Eosinophilic granulomas of the skull. Typical and atypical forms. Apropos of 10
      cases].

PMID- 4361016
TI  - [Attempt at determination of the value of certain benign biological tests for
      diagnostic orientation in outpatients. A study of 21,209 histories].

PMID- 4361017
TI  - [Paraneoplastic endocrine syndromes. 1].

PMID- 4361018
TI  - [Amnion nodosum with unusual monstrosity: unilateral electromelia and ectrouria].

PMID- 4361019
TI  - [Ultrastructure of sturgeon oocytes in the previtellogenesis period. II.
      Cytoplasm ultrastructure].

PMID- 4361020
TI  - [Antigenic structure of mouse liver cell plasma membranes. II. Antigen of bile
      capillaries of liver cells and cuticle of intestinal mucosa epithelium in mice].

PMID- 4361022
TI  - Cytochrome c reducing substances in photosynthetic electron transport.

PMID- 4361021
TI  - [Recent aspects on regulation of calcium metabolism. I. Vitamin D].

PMID- 4361023
TI  - [The role of neuronal pacemaker potentials in the mechanism of behavior].

PMID- 4361024
TI  - [Endogenous potentials in the organization of neuronal spike responses to a
      sensory stimulus].

PMID- 4361025
TI  - Topological analysis of enzymic mechanisms.

PMID- 4361026
TI  - Power spectra of cortical electric activity in the rabbit in relation to
      conditioned reflexes.
AB  - In chronic experiments on rabbits spectral and correlation characteristics of
      cerebral cortical potentials were computed to study the elaboration of a
      conditioned defense reflex. was found that the frequency spectra of the EEG are
      subject to consistent changes: a narrow-band frequency constantly developing in
      the theta range. During exposure to a positive conditioned stimulus, the maximum
      of this frequency increased relative to the pre-stimulus period and a maximal
      coherence of electrical processes was observed in a narrow theta range between
      the electrical processes of the cortical analyzers to which the conditional and
      unconditional stimuli were addressed. Different relationship was noted in the
      theta range during presentation of a differential or extinguishing stimuli: it
      became slightly slower than in the pre-stimulus period, and the coherence of the
      theta rhythms was less than maximal, remaining high at the other frequencies. It
      was concluded that the presence of highly coherent electrical processes in the
      theta range is important for the formation of conditioned reflex in the rabbit
      cerebral cortex. The processes of internal inhibition are characterized
      electrographically by disagreement of electrical processes in the theta range in
      respect to phase or frequency.

PMID- 4361027
TI  - Pain and suffering. The gate control theory.

PMID- 4361029
TI  - Urinary tract infection in hospitalized patients.

PMID- 4361028
TI  - The effects of marijuana on human sleep patterns.

PMID- 4361030
TI  - Effects of electrically induced convulsions and transmitter substances on
      ribonucleic acid turnover in brain slices.

PMID- 4361031
TI  - Effect of midbrain raphe and lateral mesencephalic stimulation on spontaneous and
      evoked activity in the lateral geniculate of the cat.

PMID- 4361033
TI  - Binocular neurons of the rabbit's visual cortex: receptive field characteristics.

PMID- 4361032
TI  - The effect of electrical stimulation, light and amino acids on the efflux of 35S
      taurine from the retina of domestic fowl.

PMID- 4361035
TI  - [Reovirus enteritis in chickens].

PMID- 4361034
TI  - Binocular neurons of the rabbit's visual cortex: effects of monocular sensory
      deprivation.

PMID- 4361036
TI  - [Blood plasma kininases in pregnant and delivering women].

PMID- 4361037
TI  - [Case of ovarian arrhenoblastoma].

PMID- 4361038
TI  - Studies on the reduction of tetrazolium salts. 3. The products of chemical and
      enzymic reduction.

PMID- 4361039
TI  - Biochemical and genetic studies on mammalian cells.

PMID- 4361040
TI  - Isolation and characterization of viruses from fetal calf serum.

PMID- 4361041
TI  - Diagnosis of testicular tumours.

PMID- 4361042
TI  - Urinary angiotensinogen loss in chronic proteinuric glomerulonephritis.

PMID- 4361043
TI  - Resonance Raman spectra of heme proteins. Effects of oxidation and spin state.

PMID- 4361044
TI  - The hydrolysis of penicillin G to 6-amino penicillanic acid by entrapped
      penicillin acylase.

PMID- 4361045
TI  - Identification of elastic tissue in human skin viewed in the scanning electron
      microscope.

PMID- 4361046
TI  - Correlations between fatty acid distribution in phospholipids and the temperature
      dependence of membrane physical state.

PMID- 4361047
TI  - A comparison of characteristic temperatures for transport in two unsaturated
      fatty acid auxotrophs of Escherichia coli.

PMID- 4361048
TI  - Electron microscopic observation of the renal lymphatic capillary after injection
      of ink solution.

PMID- 4361049
TI  - Pathogenicity of Mokola, a rabies-related virus, in baby mice.

PMID- 4361050
TI  - Neurogenic disorders affecting muscle: five-year analysis of muscle biopsies. I.
      Segmental atrophy.

PMID- 4361051
TI  - Chemotherapy of experimental brain tumors: preliminary studies.

PMID- 4361052
TI  - A new viral-hematologic etiology hypothesis for chronic and paroxysmal headache
      syndromes.

PMID- 4361053
TI  - Observations on the frog dorsal column nucleus.

PMID- 4361054
TI  - Adrenaline, DB-c-AMP and myocardial 45Ca exchange. Comparative studies in rat and
      guinea-pig auricles.

PMID- 4361055
TI  - Stimulatory effects of DB-c-AMP and adrenaline on myocardial contraction and 45Ca
      exchange. Experiments at reduced calcium concentration and low frequencies of
      stimulation.

PMID- 4361057
TI  - Are cholinergic mechanisms involved in morphine effects on motility?

PMID- 4361056
TI  - The effects of 5-hydroxytryptamine and some related compounds on the cat superior
      cervical ganglion in situ.

PMID- 4361058
TI  - [Pregnancy toxemia. Recent data].

PMID- 4361059
TI  - [Experience in the treatment of dysentery].

PMID- 4361060
TI  - An electron microscope study of the tegument of the metacercaria and adult of
      Leucochloridiomorpha constantiae (Trematoda: Brachylaemidae).

PMID- 4361061
TI  - Effects of goggle-altered color perception on sleep.

PMID- 4361062
TI  - [Cutaneous amebiasis].

PMID- 4361063
TI  - [Bacteriologic and serologic methods in the diagnosis of pertussis].

PMID- 4361064
TI  - Community control in mental health: how far can it go?

PMID- 4361065
TI  - Brief psychotherapy in the hospital setting: techniques and goals.

PMID- 4361067
TI  - [Frog skeletal muscle microsomal and mitochondrial NADH-cytochrome c reductase
      activity].

PMID- 4361068
TI  - [Herpetic infection in young children].

PMID- 4361069
TI  - [Stimulation of the hypothalamo-hypophyseal-adrenal system with piromen in
      patients with hypertension].

PMID- 4361070
TI  - [Operative stabilization of malignant tumours of the thoracal and lumbar
      vertebral column (author's transl)].

PMID- 4361072
TI  - Action potentials in the cochlea. Masking, adaptation and recruitment.

PMID- 4361071
TI  - [Clinico-biochemical studies of patients with hypothalamic pathology in the
      practice of occupation medicine].

PMID- 4361073
TI  - Seasonal change in glycerol kinase activity of goat spermatozoa.

PMID- 4361074
TI  - [Isolation and characterization of some strains of Myxovirus para-influenzae-3
      from cattle].

PMID- 4361075
TI  - [Research on the presence and significance of Adenovirus in various materials].

PMID- 4361077
TI  - Bronchial carcinoid with choroidal metastasis in an adolescent. Case report and
      ultrastructural study.

PMID- 4361076
TI  - Wilms' tumor--a clinical study of eighty-one patients.

PMID- 4361078
TI  - Down's syndrome: establishment of lymphoblastoid cell lines with trisomy 21.

PMID- 4361079
TI  - [Clinical picture, mammography, cytology, punch biopsy and plate thermography in
      extended mammary diagnosis (author's transl)].

PMID- 4361080
TI  - The deoxyribonucleoside 5'-triphosphate (dATP and dTTP) pool in
      phytohemagglutinin-stimulated and non-stimulated human lymphocytes.

PMID- 4361081
TI  - Interspecific somatic cell hybridization between asparagine-requiring and drug
      resistant cell lines.

PMID- 4361082
TI  - A technique for studying chemotaxis of leucocytes in well-defined chemotactic
      fields.

PMID- 4361083
TI  - Effects of cytochalasin B on cell division and vacuole formation in Tetrahymena
      pyriformis GL.

PMID- 4361084
TI  - Unidirectional loss of human chromosomes in rat-human hybrids.

PMID- 4361085
TI  - [Hydroxyquinoline derivatives and the nervous system].

PMID- 4361086
TI  - [Conservative treatment of stress incontinence].

PMID- 4361087
TI  - Comparison of amoebicidal action of antibiotics on Entamoeba histolytica grown
      axenically & with bacterial or trypanosome associates.

PMID- 4361088
TI  - Renal ischemia modified by an angiotensin antagonist.

PMID- 4361089
TI  - A comparison of the hormone responsiveness of the prostate and seminal vesicles.

PMID- 4361090
TI  - In vitro neoplastic transformation of bovine embryonic urothelium by simian
      vacuolating virus 40(SV40).

PMID- 4361091
TI  - A psychophysiological study of nightmares and night terrors. 3. Mental content
      and recall of stage 4 night terrors.

PMID- 4361092
TI  - Congenital epulis--a case report.

PMID- 4361093
TI  - [Extracellular phosphomonoesterase in fungi of the genus Penicillium].

PMID- 4361095
TI  - Massive gingival hyperplasia preceding dental eruption in I-cell disease.

PMID- 4361094
TI  - [Polyphosphate glucokinase activity as a differentiating trait in Actinomycetes].

PMID- 4361096
TI  - Anomalous flexor sublimis muscle with incipient carpal tunnel syndrome. Case
      report.

PMID- 4361097
TI  - [Experimental model of silicosis: a study using 22Na-labelled SiO2 (author's
      transl)].

PMID- 4361098
TI  - [On type diagnosis of space-requiring intracranial processes with cerebral
      angiography and gamma encephalography (author's transl)].

PMID- 4361099
TI  - Dexamethasone stimulation of murine mammary tumor virus expression: a tissue
      culture source of virus.
AB  - In mouse cell lines derived from mammary adenocarcinomnas, the synthetic steroid
      dexamnethasone stimulates production of murine mammary tumor virus. Viral RNA and
      antigens are increased as much as 20-fold, and culture fluid supernatants from
      steroid-treated cells contain type B particles with reverse transcriptase. These
      cells provide a possible tissue culture source of this virus and a model system
      for studying the mechanism of action of corticosteroids and the regulation of
      transcription of integrated viral DNA.

PMID- 4361100
TI  - Metabolic differences between normal and neoplastic cells: effects of
      aminonucleoside on cytoplasmic messenger RNA.
AB  - Treatment of cultured normal human fibroblasts with an adenosine analog
      (aminonucleoside of puromycin) rapidly inhibits the appearance of cytoplasmic
      messenger RNA, identified by its polyadenylate sequence. Similar treatment of
      SV40-transformed fibroblasts does not lead to such an inhibition. Cordycepin.
      another analog of adenosine. inlhibits polyadenylate-containing cytoplasmic RNA
      in both types of cell.

PMID- 4361102
TI  - [Diagnostic value of tracing of cytochrome oxidase in gonorrhea].

PMID- 4361101
TI  - [Rapid diagnosis of virus infections in patients with pseudocroup].

PMID- 4361103
TI  - Diarrhoea in intensively-reared lambs.

PMID- 4361104
TI  - Brain tumors presenting with psychiatric symptomatology. (A five-year survey).

PMID- 4361105
TI  - Ultrastructure of a mycoplasma-like avian conjunctivitis agent.

PMID- 4361106
TI  - Properties of mitochondrial thymidine kinases of parental and enzyme-deficient
      HeLa cells.

PMID- 4361107
TI  - Induction of microsomal aryl hydrocarbon (3,4-benzo(alpha)pyrene) hydroxylase and
      cytochrome P-450K in rat kidney cortex. I. Characteristics of the hydroxylase
      system.

PMID- 4361108
TI  - Specificity of sugar-phospholipid interactions.

PMID- 4361110
TI  - H2O2 production and cytochrome c peroxidase activity in mitochondria isolated
      from the trypanosomatid hemoflagellate Crithidia fasciculata.

PMID- 4361109
TI  - Kinetic studies of a hepatoma alkaline phosphatase.

PMID- 4361111
TI  - Electron spin resonance of myosin spin labeled at the S1 thiol groups during
      hydrolysis of adenosine triphosphate.

PMID- 4361112
TI  - [Study of the content of free radicals in the lungs of animals with experimental
      pneumoconioses by means of electron paramagnetic resonance].

PMID- 4361113
TI  - Effect of interferon on tumor forming ability of Walker carcinosarcoma 256 cells
      and secretion of exo-toxin by the bacillus, Clostridium welchii (type C).

PMID- 4361115
TI  - Letter: Rapid relaxation of spin equilibrium in ferric myoglobin hydroxide.

PMID- 4361114
TI  - Subtilopeptidase a cleavage in the cyclic region of the peptide antibiotic
      polymyxin B1.

PMID- 4361116
TI  - The chemistry of penicillanic acids. II. Some reactions of methyl penicillanate
      and its 6alpha-bromo- and 6,6-dibromo-derivatives.

PMID- 4361119
TI  - Radiologic seminar. CXXXVI. Linitis plastica: "leather-bottle stomach".

PMID- 4361117
TI  - High-speed liquid chromatographic separation of equine estrogens.

PMID- 4361118
TI  - Evaluation of centrifugal chromatography. I. Seperation of steroid hormones on
      silca gel.

PMID- 4361120
TI  - Blood-pressure regulation in renal failure.

PMID- 4361121
TI  - Chronic disease of liver and lungs in New Guinea.

PMID- 4361122
TI  - Pancreatic insulin in diabetes mellitus.

PMID- 4361123
TI  - Immunosuppressant agents in the treatment of glomerulonephritis. 1.
      Corticosteroid drugs.

PMID- 4361124
TI  - Steroid biosynthesis by transplantable gonadal tumors of rat.

PMID- 4361125
TI  - Receptors for androgens in rat epididymis. Interactions with 5alpha-androstane
      3alpha,17beta-diol.

PMID- 4361126
TI  - Effect of adenosine-3',5'-cyclic monophosphate on beta-hydroxy steroid
      dehydrogenase in the bovine corpus luteum.

PMID- 4361127
TI  - Serologic evidence of arbovirus activity in a moose population in Alberta.

PMID- 4361128
TI  - Inclusion body hepatitis in a prairie falcon.

PMID- 4361129
TI  - Survey for antibody to infectious bovine rhinotracheitis (IBR), bovine virus
      diarrhea (BVD) and parainfluenza 3 (PI3) in moose sera.

PMID- 4361130
TI  - Infectious pancreatic necrosis virus--temperature and age factors in mortality.

PMID- 4361131
TI  - The immune response of channel catfish. I. Basic responsiveness to soluble and
      viral antigens.

PMID- 4361132
TI  - Pseudogout syndrome in hospital patients.

PMID- 4361133
TI  - Barium enema septicemia. Occurrence in a patient with leukemia.

PMID- 4361134
TI  - Photoinactivation of Herpes simplex virus continues to look promising.

PMID- 4361135
TI  - On the phospholipids of Culex pipiens fatigans.

PMID- 4361136
TI  - Lipid composition and endogenous respiration of pig heart mitochondria.

PMID- 4361137
TI  - Postnatal changes in the phospholipid composition of livers from young lambs.

PMID- 4361139
TI  - Determination of the position of ethylenic linkages in lipids.

PMID- 4361138
TI  - Isomerization of L-glyceraldehyde to dihydroxyacetone during glyceride synthesis
      by rat liver microsomes.

PMID- 4361140
TI  - Inhibition of phospholipase C by isosteric phosphinic acid analogues of lecithin.

PMID- 4361141
TI  - Quantitative determination of urinary metabolites of cortisol in eluates from
      thin-layer chromatograms obtained by the partition method.

PMID- 4361142
TI  - Genetic duplications induced at very high frequency by ultraviolet irradiation in
      Escherichia coli.

PMID- 4361143
TI  - Mutants of Salmonella typhimurium deficient in DNA polymerase. I. Detection by
      their failure to produce colicin E1.

PMID- 4361146
TI  - Management of spina bifida cystica. II. Initial management of the treated child.

PMID- 4361145
TI  - [Characteristic clinical pictures of not primarilly traumatic peripheral nerve
      lesions. Causes and diagnosis].

PMID- 4361144
TI  - The effects of l,l-dimethyl-4-phenyl-piperazinium (DMPP) in the cat superior
      cervical ganglion in situ.

PMID- 4361147
TI  - Management of spina bifida cystica. III. Follow-up care and further treatment.

PMID- 4361148
TI  - Somatomedin and growth after renal transplantation.

PMID- 4361149
TI  - [The role of cyclic adenosino-3', 5'-monophosphate in affective psychoses].

PMID- 4361150
TI  - Neuronal circuitry in the nucleus lateralis of the cerebellum.

PMID- 4361151
TI  - [Therapy of chronic kidney insufficiency using hemodialysis].

PMID- 4361152
TI  - [Morphological and histochemical characteristics of the body reaction to the
      administration of Cl. botulinum type B toxin. I. Morphological and histochemical
      changes in the blood in botulism].

PMID- 4361153
TI  - [Bacteriocinogeny in bacteria of the genus Bordetella].

PMID- 4361154
TI  - Hydroxamic acids of natural origin.

PMID- 4361155
TI  - The biosynthesis of pteridines.

PMID- 4361157
TI  - Clostridium perfringens septicemia complicating degenerating uterine leiomyomas.

PMID- 4361156
TI  - The effects of long-term estrogen on hysterectomized women.

PMID- 4361158
TI  - Effect of prolonged continuous intracarotid arterial perfusion of hydroxyurea on
      the normal monkey brain.

PMID- 4361160
TI  - Bacterial flora of the lids and conjunctiva before, during, and after intraocular
      surgery.

PMID- 4361161
TI  - Enzymatic theory of corneal ulceration---a beginning.

PMID- 4361159
TI  - Studies on control of infections at time of intraocular surgery.

PMID- 4361162
TI  - Separation of phosphoribulokinase from enzymes of the Calvin cycle in
      Hydrogenomonas eutropha H 16.

PMID- 4361163
TI  - Proceedings: How vital is mammography in the diagnosis and management of breast
      carcinoma?

PMID- 4361164
TI  - [Biodynamics of 1,2 alpha-methyl-6-chloro-pregna-4,6-diene-17 alpha-acetoxy-3,20
      dione (cyproterone acetate) after oral administration in man. On alkyl
      substituted steroids. IX].

PMID- 4361165
TI  - Effects of REM deprivation and awakening on instrumental performance during stage
      2 and REM sleep.

PMID- 4361166
TI  - Hypnotizability predicted by digital computer-analyzed EEG pattern.

PMID- 4361167
TI  - [Wilm's tumors in childhood].

PMID- 4361168
TI  - Techniques of human breast neoplasm cell culture.

PMID- 4361169
TI  - The carbohydrate moiety of rhodopsin: lectin-binding, chemical modification and
      fluorescence studies.

PMID- 4361170
TI  - Inhibition and enhancement of mammary tumorigenesis by 7,12-dimethylbenz (a)
      anthracene in the female sprague-dawley rat.

PMID- 4361171
TI  - A chromatographic comparison of the constituents of nutmeg and mace (Myristica
      fragrans Houtt.) with those of marihuana and hashish (Cannabis sativa L.).

PMID- 4361172
TI  - Two-dimensional TLC of lipophilic compounds. Characterization of a mixed
      stationary phase permitting both adsorption TLC and reversed-partition TLC on one
      plate.

PMID- 4361173
TI  - Gas-liquid chromatographic separation of equine estrogens.

PMID- 4361174
TI  - Evidence for dual corticosteroid-receptor mechanisms in the feedback control of
      adrenocorticotrophin secretion.

PMID- 4361175
TI  - Editorial: Do human tumors show a chromosome pattern specific for each etiologic
      agent?

PMID- 4361176
TI  - Neoplasms and amyloidosis in strains of mice treated with 3-methylcholanthrene.

PMID- 4361177
TI  - Heterogeneity of virus production and antigenicity detected in cell clones
      derived from a "nonproducer" neoplasm induced by Moloney murine sarcoma virus.

PMID- 4361178
TI  - Rescue of cell-transforming virus from a non-virus-producing bovine cell culture
      transformed by feline sarcoma virus.

PMID- 4361179
TI  - Mammalian sarcoma-leukemia viruses. I. Infection of feline, bovine, and human
      cell cultures with Snyder-Theilen feline sarcoma virus.

PMID- 4361180
TI  - Replicating type-C virus particles in monolayer cell cultures of tissues from
      cattle with lymphosarcoma.

PMID- 4361181
TI  - Immunoglobulin analysis of C57BL mice infected with a radiation-induced leukemia
      virus.

PMID- 4361182
TI  - Virus particles in primordial germ cells of fetal guinea pigs.

PMID- 4361183
TI  - Different chromosome morphology of diploid and aneuploid malignant cells.

PMID- 4361184
TI  - In vitro effects of melanocyte-stimulating hormone, adrenocorticotropic hormone,
      17 beta-estradiol, or testosterone propionate on Cloudman S91 mouse melanoma
      cells.

PMID- 4361185
TI  - Effect of feline leukemia virus on transferrred hamster fetuses.

PMID- 4361186
TI  - Control of the enzyme systems in plasma renin activity measurement by angiotensin
      I radioimmunoassay.

PMID- 4361187
TI  - Mixed Mullerian tumour of the corpus uteri.

PMID- 4361188
TI  - Clinicopathologic conference. Cholecystitis, pericholecystic abscess, and
      septicemia due to Clostridium perfringens. Case presentation.

PMID- 4361189
TI  - Letter: Nephroblastoma.

PMID- 4361190
TI  - [Virus infections in pregnancy].

PMID- 4361191
TI  - [Effect of angiotensin II on autotransplanted kidney].

PMID- 4361192
TI  - A diallel analysis of the genetic underpinnings of mouse sleep.

PMID- 4361193
TI  - The water tank technique: avoidance conditioning as a function of water level and
      pedestal size.

PMID- 4361194
TI  - Absence of ponto-geniculo-occipital (PGO) spikes in rats.

PMID- 4361195
TI  - Hepatic scintiangiographic patterns.

PMID- 4361196
TI  - Angiographic features of focal lymphoma of the liver.

PMID- 4361197
TI  - [The importance of various dietary microelements and their combinations for the
      enzyme activity of the animal body].

PMID- 4361198
TI  - [Fine structure of a polyoma virus-induced sarcoma in the kidney of rats during
      its growth (author's transl)].

PMID- 4361199
TI  - Comparative study of the incorporation of 32P into the phospholipids of membranes
      from Novikoff hepatoma ascites cells and liver cells from normal and tumor
      bearing animals.

PMID- 4361200
TI  - [Diagnosis of chemodectoma].

PMID- 4361201
TI  - Diabetes and hypertensive vascular disease. Mechanisms and treatment.

PMID- 4361202
TI  - The REM state and drugs.

PMID- 4361203
TI  - Radiopertechnetate flow study and liver scan in a case of benign hepatoma (liver
      cell adenoma).

PMID- 4361211
TI  - Wilm's-aniridia syndrome with transient hypo-gamma-globulinaemia of infancy.

PMID- 4361212
TI  - The pituitary and primary hypothyroidism. Enlargement and unusual growth hormone
      secretory responses.

PMID- 4361213
TI  - Lymphangiography in patients with pulmonary dysfunction.

PMID- 4361214
TI  - Thyrotoxicosis from molar thyrotropin.

PMID- 4361215
TI  - Membrane properties and inhibitory innervation of the circular muscle cells of
      guinea-pig caecum.
AB  - 1. The membrane properties of the circular muscle cells of guinea-pig caecum and
      nervous factors influencing the muscle activity were studied with micro
      electrodes using partition and field stimulating methods.2. The mean membrane
      potential was -52 mV. Spontaneous discharges appeared as regular bursts between
      silent periods, as regular spikes without silent period, or as regular slow
      potential changes with superimposed spikes.3. Spontaneous spikes with overshoot
      were frequently observed. The mean maximum rate of rise was 5.2 V/sec. The mean
      conduction velocity of evoked spikes was 5.4 cm/sec.4. The amplitude of the
      elctrotonic potential was linearly proportional to the current applied by the
      partition stimulating method. The spatial decay of the electrotonic potential
      along the tissue was exponential, with a mean length constant of 1.7 mm.5. The
      time constants of the membrane calculated from the electrotonic potential, and
      from the conduction velocity, length constant and time course of the foot of the
      spike were about 200 and 100 msec respectively. These results indicate that the
      circular muscle of guinea-pig caecum possesses cable like properties.6. Field
      stimulation (0.3 msec pulse duration) to the circular muscle evoked three
      different responses successively, i.e. initial depolarization (initial excitatory
      junction potential) with or without spike, hyperpolarization (inhibitory junction
      potential) and delayed depolarization (delayed excitatory junction potential)
      with or without spikes.7. These three different potential changes were completely
      blocked by treatment with tetrodotoxin (5 x 10(-6) g/ml.), and both the initial
      and late excitatory junction potentials were blocked by treatment with atropine
      (5 x 10(-5) g/ml.).8. The distribution of inhibitory nerves in the circular
      muscle cells was investigated. The results indicate that inhibitory nerves arise
      from Auerbach's plexus situated just beneath the taenia coli and the nerve
      branches spread over the whole distance from one taenia coli to the next along
      the ciruclar muscle cells, a width of about 3 mm.9. The mean conduction velocity
      of excitation of the inhibitory nerves was 16.0 cm/sec. Hexamethonium, in a
      concentration of 5 x 10(-6) g/ml. depolarized the circular muscle membrane and
      lowered the rate of rise and fall of spike, but did not block the generation of
      inhibitory junction potentials.

PMID- 4361217
TI  - The role of the nurse in a drug crisis center.

PMID- 4361216
TI  - The binding of acetylcholine to receptors and its removal from the synaptic
      cleft.
AB  - 1. Acetylcholine (ACh) noise and miniature end-plate potentials were recorded
      with focal external micro-electrodes.2. The effect of prostigmine on the time
      course of the ;molecular' and ;quantal' transmitter actions was studied.
      Prostigmine (10(-6) g/ml.) has little or no effect on the duration of the
      molecular ;gating action', while it greatly prolongs the quantal conductance
      change.3. After inhibition of ACh hydrolysis, the removal of the transmitter from
      the synapse is generally too slow to be accounted for by free diffusion. It is
      suggested that diffusion is delayed by binding to post-synaptic receptors. This
      is consistent with the finding that receptor blockage by curare or alpha
      bungarotoxin shortens as well as reduces quantal transmitter action.4. The
      correlated effects of the receptor-blocking agents, on size and time course of
      the miniature end-plate currents, were subjected to a simple analysis. Its result
      suggests that after inhibition of cholinesterase about two thrids of the quantal
      packet of ACh combines with post-synaptic receptors.5. During focal external
      recording the effect of prostigmine on the time course of miniature end-plate
      potentials can become exaggerated due to what appears to be a compression
      artifact which obstructs outward diffusion of the transmitter.

PMID- 4361218
TI  - The pros and cons of methadone maintenance.

PMID- 4361219
TI  - The clinical specialist in the geographic unit system.

PMID- 4361221
TI  - One interdisciplinary planning team: a case study.

PMID- 4361220
TI  - Infantile autism: the puzzle.

PMID- 4361222
TI  - Korsakoff's syndrome.

PMID- 4361224
TI  - Higher education in nursing.

PMID- 4361223
TI  - Black patient, white therapist.

PMID- 4361225
TI  - A follow-up survey of the post-treatment adaptation of former day hospital
      patients.

PMID- 4361226
TI  - Corticosteroid therapy for rheumatoid arthritis.

PMID- 4361227
TI  - The use of glucocorticoids in intestinal disease.

PMID- 4361228
TI  - The use of antibodies to study cell structure and metabolism.

PMID- 4361229
TI  - The radiotherapy of nasopharyngeal angiofibroma.

PMID- 4361230
TI  - A computer model for the study of image formation of blood vessels smaller than
      the exposing focal spot.

PMID- 4361231
TI  - [Morphohistochemical aspects of the interrelationship between the salivary duct
      epithelium and the stromal epithelium in the mixed salivary glands in man].

PMID- 4361232
TI  - Giant fibro-adenoma (cystosarcoma phyllodes) in adolescent females--a
      clinicopathological study.

PMID- 4361234
TI  - Amoebic perforation of the intestine in children.

PMID- 4361233
TI  - The reduction of surgical wound infections by topical cephaloridine: a controlled
      clinical trial.

PMID- 4361235
TI  - Multiple intestinal malignancies and prolonged survival in a young woman.

PMID- 4361236
TI  - Cancer of the biliary system: a study of 445 cases.

PMID- 4361237
TI  - Proceedings: Carcinoma of the urachus.

PMID- 4361238
TI  - [Reimplantation of limbs after resection of neoplastic segment. Report of 8
      cases].

PMID- 4361239
TI  - Retroperitoneal tumors in children.

PMID- 4361240
TI  - Letter: Phosphodiesterase: an important role in cyclic nucleotide regulation in
      the retina.

PMID- 4361241
TI  - Letter: Potential hazards of HClO4 in heated systems where esters are involved.

PMID- 4361242
TI  - A depression of cell-mediated immunity to measles antigen in patients with
      systemic lupus erythematosus.
AB  - Using the direct migration inhibition test, response to measles antigen in
      patients with systemic lupus erythematosus (SLE) was found to be decreased when
      compared with that of normal subjects. No alteration was observed in similar
      experiments using parainfluenza type 1 and rubella antigens. The specific
      decrease in measles antigen effect showed no obvious correlation with activity of
      SLE or with the presence of lymphocytotoxic antibodies. Whether the specificity
      of the decrease in reactivity is due to some particular relationship between the
      measles virus or antigen and SLE, or to the possibility that measles reactivity
      is a more sensitive indicator of a generalized defect of cell-mediated immunity,
      remains unclear.

PMID- 4361243
TI  - Interaction of cholera toxin and toxin derivatives with lymphocytes. I. Binding
      properties and interference with lectin-induced cellular stimulation.
AB  - The interaction of cholera toxin and a number of toxin derivatives, containing
      different proportions of light and heavy toxin-composing subunits (L and H), with
      mouse lymphocytes was studied. Experiments with [(125)I]toxin showed that a
      single cell can rapidly, within minutes, bind up to 40,000 molecules of toxin,
      the association constant was estimated to 7 +/- 4 x 10(8) liters/mol, and binding
      was found to be very similar at 37 degrees C and 5 degrees C. Immunofluorescence
      studies revealed that the toxin attachment is located on the cell surface, and
      that purified L subunit but not H subunit binds to the cells. A natural cholera
      toxoid, built up by aggregated L subunits, showed almost identical binding
      properties as toxin to the cells. Pure G(M1) ganglioside, the proposed membrane
      receptor structure for toxin, prevented entirely the cellular binding of both
      toxin and toxoid. Cholera toxin in concentrations down to approximately 5 x 10(
      11) mol/liter (corresponding to 10 bound molecules/cell) inhibited thymus cells
      from being stimulated to DNA synthesis by concanavalin A (con A), and spleen
      cells from such stimulation by phytohemagglutinin. The G(M1) ganglioside but not
      a series of other pure structurally related gangliosides and neutral
      glycosphingolipids neutralized this toxin activity. Toxin derivatives which, in
      similarity with toxin, possessed H as well as L subunits but in other
      proportions, were potent inhibitors of con A-induced thymocyte stimulation,
      whereas the natural toxoid (aggregated L subunits), purified toxin L subunit and
      purified toxin H subunit were up to 300-fold less active on a weight basis. The
      capacity of cholera proteins to inhibit con A-induced thymocyte stimulation
      correlated well with their activity in the rabbit intradermal toxicity assay. The
      inhibitory action of cholera toxin on con A-induced thymocyte stimulation did not
      depend on decreased cell viability from the toxin treatment, nor was it caused by
      a reaction between toxin and con A. [(125)I]con A bound equally well to the cells
      when toxin was present as when it was absent, which proves that the toxin did not
      compete for cellular con A receptors. Nor did the toxin seem to disturb the
      general mobility of membrane receptors or their ability to accumulate in caps. It
      is concluded that the L type of subunit confers rapid and firm binding of cholera
      toxin to lymphocyte membranes, probably to G(M1) ganglioside receptors. For
      biologic activity the additional presence of H subunit is important. One
      manifestation of toxin action on lymphocytes is inhibition of lectin-induced DNA
      synthesis; probably this effect relates to the ability of cholera toxin to raise
      the levels of intracellular cyclic 3'5'-adenosine monophosphate.

PMID- 4361244
TI  - Interferon production of human leukemic cells--an in-vitro assay.

PMID- 4361245
TI  - An apparently new enterovirus isolated from patients with disease of the central
      nervous system.

PMID- 4361246
TI  - Type B hepatitis antigen and antibody among prostitutes and nuns: a study of
      possible venereal transmission.

PMID- 4361247
TI  - Microbiologic study of street heroin and injection paraphernalia.

PMID- 4361248
TI  - Virucidal activity of H2O2-generating bacteria: requirement for peroxidase and a
      halide.

PMID- 4361249
TI  - Pulmonary defense mechanisms in consolidated and nonconsolidated regions of lungs
      infected with Sendai virus.

PMID- 4361250
TI  - Chemical studies of potential relevance to penicillin hypersensitivity: kinetic
      studies of methicillin, phenoxymethylpenicillin and their penicillenic acids.

PMID- 4361251
TI  - Subcellular distribution of cardiac glycosides in rabbit and rat myometrium and
      their binding to isolated plasma membrane.

PMID- 4361252
TI  - Pharmacological analysis of synaptically mediated increase in cyclic adenosine
      monophosphate in rabbit superior cervical ganglion.

PMID- 4361253
TI  - The ultrastructure and function of the tentacle in Rhyncheta cyclopum Zenker
      (Ciliatea, Suctorida).

PMID- 4361254
TI  - [Acute kidney failure].

PMID- 4361255
TI  - [Mechanism of formation of dental calculus in man].

PMID- 4361256
TI  - [Cytomegalovirus--isolation on tissue culture].

PMID- 4361257
TI  - Mutagenic properties of DNA- and RNA-containing viruses nonvirulent for
      Drosophilia.

PMID- 4361258
TI  - Study of the properties of a DNA-polymerase-deficient mutant of Escherichia coli.

PMID- 4361259
TI  - [Fine structural localization of acetylcholinesterase in the neurons and synapses
      of the hippocampus].

PMID- 4361260
TI  - [Electron microscopic studies of the oculomotor nerve nucleus in Salmo irideus
      (Gibbons 1855)].

PMID- 4361261
TI  - [Ontogenesis and ultrastructure of goblet cells in the intestine of the carp
      (Cyprinus carpio L)].

PMID- 4361262
TI  - Pharmacological fibrinolysis.

PMID- 4361264
TI  - The mechanism of intragenic recombination.

PMID- 4361263
TI  - Inhibition of platelet aggregation by isochinoline derivatives.

PMID- 4361265
TI  - Paramutation.

PMID- 4361266
TI  - Genetics of resistance to environmental stresses in Drosophila populations.

PMID- 4361267
TI  - Pharmacological actions of a novel O-acetylsalicylic acid composition.

PMID- 4361269
TI  - Insulin interactions with its receptors: experimental evidence for negative
      cooperativity.

PMID- 4361268
TI  - [Prolactin cell tumors in animal experiments and in man].

PMID- 4361270
TI  - Cyclic AMP binding to living cells of Dictyostelium discoideum in presence of
      excess cyclic GMP.

PMID- 4361271
TI  - Determination of oxidation and spin states of heme iron. Resonance Raman
      spectroscopy of cytochrome c, microperoxidase, and horseradish peroxidase.

PMID- 4361272
TI  - A new procedure for the reconstitution of biologically active phospholipid
      vesicles.

PMID- 4361273
TI  - Effect of potassium cyanate on the catalytic activities of carbamyl phosphate
      synthetase.

PMID- 4361274
TI  - [Maintenance of pregnancy in the castrated rat using ACTH and estradiol].

PMID- 4361275
TI  - [Obtaining regulation mutants from the biosynthesis pathway of lysine in a strain
      of Corynebacterium resistant to lysine analogues].

PMID- 4361276
TI  - [Demonstration of antiviral immunity in insects].

PMID- 4361277
TI  - [Induction of synthesis of Simian 40 virus (SV40) in transformed hamster cells,
      sensitive and resistant to actinomycin D].

PMID- 4361278
TI  - Neutrophilic leukocytes in immunologic reactions in vitro. 3. Pharmacologic
      modulation of lysosomal constituent release.

PMID- 4361279
TI  - Detection of antigens determined by the Epstein Barr virus (EBV) in human
      lymphoblastoid cell culture lines by elution of specific radioiodine labeled
      antibody.

PMID- 4361280
TI  - Mammalian collagenases.

PMID- 4361282
TI  - [Hypothalamic releasing and inhibiting hormones].

PMID- 4361283
TI  - The sequential inactivation of glycogen phosphorylase and activation of glycogen
      synthetase in liver after the administration of glucose to mice and rats. The
      mechanism of the hepatic threshold to glucose.

PMID- 4361284
TI  - Pulse-recovery studies on cycloheximide-insensitive protein synthesis in
      Neurospora. Association of products with cytochrome-oxidase.

PMID- 4361281
TI  - Lipid lowering drugs and hyperlipidaemia.

PMID- 4361285
TI  - A comparison of mitochondrially synthesized proteins from whole mitochondria and
      cytochrome oxidase in Neurospora.

PMID- 4361286
TI  - Measurements of the concentration of active sites in preparations of yeast
      alcohol dehydrogenase.

PMID- 4361287
TI  - The effect of adenosine analogues on the ATP-pyrophosphate exchange reaction
      catalysed by methionyl-tRNA synthetase.

PMID- 4361288
TI  - A simplified procedure for the assay of adenosine 3':5'-monophosphate by the
      activation of liver phosphorylase.

PMID- 4361289
TI  - [Editorial: The role of enzyme histochemistry in modern pathology].

PMID- 4361290
TI  - Study of some glycolytic enzymes of mouse fibrosarcoma.

PMID- 4361291
TI  - Epidemiological and biochemical studies on thiamine-less dwarf-colony variants of
      Staphylococcus aureus as etiological agents of bovine mastitis.
AB  - Dwarf-colony (D) variants of Staphylococcus aureus are relatively widespread
      etiological agents of bovine mastitis in Israel. D strains grow on ordinary solid
      nutrient media with pinpoint, transparent colonies. An epidemiological study
      indicated that these variants are more communicable than normal (N) S. aureus
      strains. Biochemically, several types of metabolic defects have been demonstrated
      among the D strains: strains from one herd were pantothenate-less, most of the
      other isolates were thiamine-less, and a few of them were both thiamine-and
      pantothenate-less. Among the thiamineauxotrophs were a few (from one herd) which
      were unable to concentrate thiamine-thiazole, whereas all of the other strains
      required thiamine-pyrimidine (HMP) in the form of pyrophosphate (HMP-PP). At
      least some of these D strains were defective in three functions: concentrative
      uptake of HMP, phosphorylation of HMP, and phosphorylation of HMP-monophosphate.
      Since mutants with normal growth occurred readily, we assumed that the
      information for these three functions exists on a polycistronic operon.
      Quantitative requirements for HMP-PP varied highly among the D strains, and other
      data also indicated that HMP-PP-requiring strains had not developed from a common
      source.

PMID- 4361293
TI  - Capsular polysaccharide of Clostridium perfringens Hobbs 10.
AB  - A capsular polysaccharide was isolated from a strain of Clostridium perfringens
      Hobbs 10 type A by cold-water extraction of whole, heavily encapsulated cells.
      The water-soluble polymer was isolated by alcohol precipitation and purified by
      treatment with chloroform-butanol, cetytrimethylammonium bromide, and column gel
      permeation chromatography by using Bio-Gel A-5m agarose. The formation of a
      single precipitin line, when the isolated polysaccharide was reacted with its
      homologous antisera by double diffusion in gel, was considered a criterion of
      immunochemical purity. The purified polymer appeared as a single peak when eluted
      from diethylaminoethyl-Sephadex with a linear gradient of NaCl. The
      polysaccharide was composed of glucose, galactose, galactosamine, and iduronic
      acid in a molar ratio of 4.1:5.1.7:1, respectively. These constituents accounted
      for 83% of the dry weight. The polysaccharide appeared to have a molecular weight
      of 40,000 and exhibited aggregation up to 120,000. A trace of peptide material
      could not be removed during purification.

PMID- 4361292
TI  - Lipid catabolism of relapsing fever borreliae.
AB  - Relapsing fever borreliae require lipid compounds for growth in vitro. In this
      study, the major pathways of lipid catabolism in three species of tick-borne
      relapsing fever borreliae were investigated. Thin-layer chromatography was used
      to compare chloroform-methanol extracts of fresh culture media with extracts of
      exhausted culture media after organisms were removed by centrifugation. The
      chromatographic data demonstrated that lysolecithin was removed from the culture
      media during growth of the spirochetes, whereas lecithin, sphingomyelin,
      triglycerides, and cholesterol esters were not affected by growth of the
      organisms. Sonic extracts of the organism were tested for the presence of
      specific enzymes of lipid catabolism. Lysolecithinase, glycerophosphorylcholine
      diesterase, and acid phosphatase activities were demonstrated. Thus, these
      organisms can sequentially dissimilate lysolecithin to fatty acids, choline,
      inorganic phosphate, and glycerol. Assays for phospholipases A, C, and D, alpha
      glycerophosphate dehydrogenase, alkaline phosphatase, and lipase were negative.

PMID- 4361295
TI  - Bactericidal activity of aerobic and anaerobic polymorphonuclear neutrophils.
AB  - Human polymorphonuclear neutrophils (PMN) were made anaerobic by nitrogen washout
      (oxygen saturation <1%, Eh < -42 mV at pH 7.0), and the ability of the cells to
      kill bacteria was assayed and compared to the bactericidal activity of aerobic
      PMN. Anaerobic PMN were able to kill Staphylococcus epidermidis, Enterococcus,
      viridans streptococci, Pseudomonas aeruginosa, Peptostreptococcus anaerobius,
      Bacteroides fragilis, Clostridium perfringens, and Peptococcus magnus normally.
      Organisms that were not killed normally by anaerobic PMN included Staphylococcus
      aureus (strains Wood 46 and 502a), Escherichia coli, Serratia marcescens,
      Klebsiella pneumoniae, Proteus vulgaris, and Salmonella typhimurium. These
      findings suggest that mechanisms other than those dependent on hydrogen peroxide
      may be important in the killing of some bacteria.

PMID- 4361294
TI  - Collagenolytic activity of dental plaque associated with periodontal pathology.
AB  - Certain dental plaques, removed from sites of gingival and periodontal pathology
      in mentally retarded, institutionalized individuals, when incubated in phosphate
      buffer with Achilles tendon collagen, gave rise to an increase in ninhydrin
      positive material. These plaques, while showing great variability, released
      significantly more ninhydrin-positive material per milligram of plaque (wet
      weight) than did either the endogenous or heat-treated controls. Certain plaques
      could also break down soluble, tritiated, labeled collagen isolated from the
      calvaria of chicken embryos. Bacteroides melaninogenicus and Clostridia
      histolyticum were found in plaques by either fluorescent antibody or cultural
      methods. C. histolyticum, when detected, accounted for about 0.01 to 0.1% of the
      bacteria in plaque. A conspicuous isolate from some plaques was a Bacillus
      species which rapidly liquefied gelatin. Cell-free supernatants of this organism
      were able to degrade about 50 to 70% of the soluble collagen when incubated at 36
      C. C. histolyticum ATCC 8034 caused an 80% degradation of the collagen under the
      same conditions of incubation. The Bacillus strains were facultative, could
      ferment glucose, reduced nitrate to nitrite, and were catalase, indole, and
      urease negative. The limited taxonomic information for the isolates is compatible
      with the description given for Bacillus cereus.

PMID- 4361296
TI  - Replication or inactivation of different viruses by human lymphocyte
      preparations.
AB  - Cultures of phytohemagglutinin-stimulated, unstimulated, and frozen and thawed
      mononuclear (as controls) cells from normal human donors were infected with
      different viruses. A variable pattern of virus infectivity was noted, and
      influenza and Coxsackie virus were rapidly inactivated even by stimulated
      lymphocytes. Direct inactivation by lymphocytes may be one form of host defense
      in infection by some viruses.

PMID- 4361297
TI  - Combined effects of phytohemagglutinin and staphylococcal enterotoxin B on
      deoxyribonucleic acid synthesis during blast transformation in human lymphocytes.
AB  - Three mitogenic agents, phytohemagglutinin (PHA), staphylococcal enterotoxin B
      (SEB), and concanavalin A (Con A) were tested for their effects on
      deoxyribonucleic acid (DNA) synthesis in the normal human lymphocyte. When
      optimal concentrations of PHA and SEB were combined, tritiated thymidine
      incorporation in lymphocytes derived from several donors was enhanced
      significantly. In the presence of graded concentrations of one of these mitogens
      added to fixed optimal concentrations of the other, this enhancement was shown to
      be additive. By contrast, when PHA or SEB were combined with Con A, the resulting
      thymidine incorporation was slightly lower than for either mitogen alone. An
      inhibition of further thymidine incorporation when puromycin was added to
      lymphocytes incubated with PHA and SEB suggested that the additive effect of
      these mitogens was due to increased enzyme synthesis. To define potential
      differences in mechanisms of action underlying the additive effect of SEB and
      PHA, the relative contribution of the de novo and salvage pathways for pyrimidine
      biosynthesis was tested with cytidine, a specific salvage pathway inhibitor.
      Cytidine (10(-3) M) inhibited synthesis through the salvage pathway, but did not
      significantly alter induction of carbamyl phosphate synthetase II, the rate
      limiting enzyme for the de novo pathway. An inhibition of DNA synthesis by
      millimolar cytidine concentrations in lymphocytes incubated with PHA or SEB,
      singly or in combination, suggested that pyrimidines for the observed enhancement
      of DNA synthesis were derived largely via the salvage pathway.

PMID- 4361299
TI  - Reaction of phenylmethanesulfonyl-alpha-chymotrypsin with hydrogen peroxide and
      other nucleophiles.

PMID- 4361298
TI  - Antibody against Clostridium perfringens type A enterotoxin in human sera.
AB  - Antibody against Clostridium perfringens type A enterotoxin was found in 82% of
      Brazilian and 65% of American serum samples.

PMID- 4361300
TI  - Stereoelectronic properties of metalloenzymes. I. A comparison of the
      coordination of copper (II) in galactose oxidase and a model system, N,N'
      ethylenebis(trifluoroacetylacetoniminato)copper(II).

PMID- 4361301
TI  - Stereoelectronic properties of metalloenzymes. II. Effects of ligand coordination
      on the electron spin resonance spectrum of galactose oxidase as a probe of
      structure and function.

PMID- 4361302
TI  - Cation radicals of tetraalkylporphyrins.

PMID- 4361303
TI  - Studies on the sarcoplasmic reticulum of rat, cat and sheep intrafusal fibres.

PMID- 4361304
TI  - The ultrastructure of Leydig cells in the testis of the domestic fowl.

PMID- 4361305
TI  - Report on microbiological methods.

PMID- 4361306
TI  - Pressure accelerated chromatography through microparticulate silica columns
      packed by centrifugation.

PMID- 4361307
TI  - Tumorous hyperparathyroidism in hypophosphatemic vitamin D--resistant rickets.

PMID- 4361308
TI  - Novel analogs of nucleoside 3',5'-cyclic phosphates. I. 5'-Mono- and dimethyl
      analogs of adenosine 3',5'-cyclic phosphate.

PMID- 4361309
TI  - [A pharmacokinetic study on the metabolism and excretion of sulpyrin in the rats
      (author's transl)].

PMID- 4361310
TI  - [The dose effect of sulpyrin on the metabolism and excretion rates in rats
      (author's transl)].

PMID- 4361311
TI  - [The effect of administration routes on the absorption, metabolism and excretion
      of sulpyrin in rats (author's transl)].

PMID- 4361312
TI  - [Physicochemical properties of medicinal agents. II. Relationship between acid
      dissociation constants of arylsulfonylurea derivatives and the Hammett equation
      (author's transl)].

PMID- 4361313
TI  - [Case of pulmonary metastasis of ovarian cancer erroneously diagnosed and treated
      as pulmonary tuberculosis for a long time].

PMID- 4361314
TI  - [Oxidation-reduction processes and bioenergetics in cardiac insufficiency].

PMID- 4361315
TI  - [Experimental study of para-influenzal-staphylococcal infection].

PMID- 4361316
TI  - [Study of the leukotoxic action of Clostridium perfringens type A toxin on the
      phagocytic activity of blood neutrophils taking into consideration the leukocytic
      reaction].

PMID- 4361317
TI  - [Letter: Huneke's neural therapy?].

PMID- 4361319
TI  - [Somatic characteristics of children with Shereshevskii-Turner syndrome].

PMID- 4361318
TI  - Phospholipids in biology and medicine (second of two parts).

PMID- 4361320
TI  - [Effect of therapy on the dynamics of growth and maturation of skeletal bones in
      patients with different forms of nanism].

PMID- 4361321
TI  - Eighteenth Bowditch lecture. Motor aspects of cerebellar control.

PMID- 4361322
TI  - Role of viruses in the etiology of congenital malformations.

PMID- 4361323
TI  - Surgery of atherosclerosis below the inguinal ligament. The value of
      profundaplasty.

PMID- 4361324
TI  - Separation of prostaglandins A, B and C by thin-layer chromatography on ferric
      chloride impregnated silica gel.

PMID- 4361325
TI  - A review of myelography.

PMID- 4361326
TI  - [Wilms' tumor and congenital malformations].

PMID- 4361327
TI  - [Antigenic structure of the foot-and-mouth disease virus (a review of the foreign
      literature)].

PMID- 4361328
TI  - [Detection of anti-foot-and-mouth disease antibodies by immunofluorescence].

PMID- 4361329
TI  - [Detection of the foot-and-mouth disease virus in slaughter products].

PMID- 4361330
TI  - [Ensuring sterility in culturing the foot-and-mouth disease virus by Frenkel's
      method].

PMID- 4361331
TI  - [Viral carrier state in animals that have had foot-and-mouth disease].

PMID- 4361332
TI  - Food safety and food poisoning.

PMID- 4361333
TI  - The metabolism of tamoxifen (I.C.I. 46,474). I. In laboratory animals.

PMID- 4361334
TI  - On the effects and the mechanism of action of corticosteroids in normal and
      neoplastic target tissues: findings and hypotheses, with a review of information
      on intracellular steroid receptors in general.

PMID- 4361335
TI  - Effect of cyclic AMP and polyadenylic acid treatment on the delayed
      hypersensitivity of guinea pigs.

PMID- 4361336
TI  - Antiviral effect of 1-aminoadamantane derivatives in vitro.

PMID- 4361337
TI  - The National Center for Health Statistics. A research resource for pediatricians.

PMID- 4361338
TI  - Use of oxandrolone for growth stimulation in children.

PMID- 4361339
TI  - Herpesvirus hominis infections in the fetus and the newborn.

PMID- 4361341
TI  - A new look at the brain-damaged adult.

PMID- 4361342
TI  - [Tubule agglutination and indirect immunofluorescence for titer determination
      during immunization of rabbits with Clostridium (Cl.) perfringens (welchii) type
      A,C and E].

PMID- 4361344
TI  - [Pituitary cells with corticotropic activity in the lerot (Eliomys quercinus):
      superposition of optic microscopy (immunofluorescene and dyes) and electron
      microscopy].

PMID- 4361343
TI  - The excitable membrane-biophysical theory and experiment.

PMID- 4361345
TI  - [Reduction of nitroxide radicals by photoreceptive cell membranes].

PMID- 4361346
TI  - The process of collaboration. II. Implementation and its discontents or you don't
      learn that in school.

PMID- 4361347
TI  - Incorporation and replication of foreign metaphase chromosomes in cultured
      mammalian cells.

PMID- 4361348
TI  - Colony formation of mammalian cells on agar plates and its application to
      Lederberg's replica plating.

PMID- 4361349
TI  - c-AMP and the cell cycle: inhibition of growth stimulation.

PMID- 4361350
TI  - [Histological changes in peripheral nerve after cryosurgery (author's transl)].

PMID- 4361351
TI  - The federal role in health: a conversation with Charles C. Edwards, M.D.,
      assistant Secretary for Health, Department of Health, Education, and Welfare.

PMID- 4361352
TI  - The role of phosphorylation in the uptake of thymidine in mammalian cells.

PMID- 4361354
TI  - Attenuation of rhinovirus type 15: relation of illness to plaque size.
AB  - Rhinovirus type 15 passaged three times in WI-38 cells produced illness in only
      one of 35 volunteers, but infection resulted in formation of significant
      quantities of antibodies in the serums of 100%, and in nasal secretions of 89%,
      of infected volunteers. The inoculum contained large- (60%) and small- (40%)
      plaque variants. "Purified" large- and small-plaque inocula were prepared, and
      each was administered to 20 volunteers. There was a significant association of
      illness with the small-plaque inocula (P < 0.01) but the incidence of infection,
      quantitative virus shedding patterns, and mean serum and nasal secretory
      antibodies were not significantly different between the two groups. These
      findings suggest that plaque size may be an in vitro marker of attenuation of
      illness production by rhinoviruses.

PMID- 4361355
TI  - Prevention of malnutrition.

PMID- 4361356
TI  - Prospects for decline in population growth in the developing nations.

PMID- 4361353
TI  - Effect of induced interferon in experimental rhinovirus infections in volunteers.
AB  - Nasal administration of an interferon inducer, CP-20,961 (N, N-dioctadecyl-N', N'
      bis(2-hydroxyethyl)propanediamine), was evaluated in a double-blind, placebo
      controlled study of experimental rhinovirus infection in 29 volunteers.
      Detectable nasal interferon developed in 10 of 15 subjects treated with CP
      20,961, and 2 of 14 in the group receiving placebo (P < 0.006). Titers of CP
      20,961-induced interferon ranged from 10 to 250 international units,
      concentrations similar to those observed in rhinovirus infections. Ten in the CP
      20,961 group and eight in the placebo group became ill (P > 0.05). However, mean
      total sign scores were significantly diminished among CP-20,961-treated subjects
      as compared with placebo-treated subjects (P < 0.025). No significant effect was
      noted on quantitative virus shedding patterns or neutralizing antibody responses.
      These findings suggest that such concentrations of induced interferon do not
      protect against rhinovirus infection, and that factors other than interferon may
      be important in recovery from rhinovirus infection.

PMID- 4361357
TI  - Acceptance of Elizabeth Blackwell Award.

PMID- 4361358
TI  - A new era: challenges for the woman physician. (Hey, no fair. There are hardly
      any lady doctors.).

PMID- 4361359
TI  - Fluorescence studies of possible protein-protein interactions in model
      lipoprotein complexes.

PMID- 4361360
TI  - Cell agglutination mediated by concanavalin A and the dynamic state of the cell
      surface.

PMID- 4361361
TI  - Initiation of DNA replication in mammalian cells and its inhibition by reovirus
      infection.

PMID- 4361362
TI  - The enzymic make-up of the left and right ventricles of the normal rat heart and
      the changes shown on exposure to exercise and hypoxic exercise.

PMID- 4361363
TI  - Early components of the averaged electroencephalic response to constant level
      clicks during all-night sleep.

PMID- 4361364
TI  - Consequences of excess hormonal secretion in digestive disease.

PMID- 4361365
TI  - [The quantitative estimation of unconjugated cortisol, cortisone and cortexolone
      in collected urine by thin-layer chromatography (author's transl)].

PMID- 4361366
TI  - [Study of the hypothalamo-adrenohypophyseal system in ulcer diseases].

PMID- 4361368
TI  - Induction of liver tumours in rats by a single treatment with nitroso compounds
      given after partial hepatectomy.

PMID- 4361367
TI  - [Diagnosis and therapy of bronchial carcinoma].

PMID- 4361369
TI  - [Lysosomal enzymopathies].

PMID- 4361370
TI  - Separation and radioimmunoassay of f alpha prostaglandins using silica gel micro
      columns.

PMID- 4361371
TI  - Stimulatory effects of prostaglandin e-1 on rat anterior pituitary cyclic AMP and
      luteinizing hormone release.

PMID- 4361372
TI  - TRH and prostaglandin action on rat anterior pituitary: dissociation between
      cyclic AMP levels and TSH release.

PMID- 4361373
TI  - Prostaglandins and cyclic nucleotides in Moloney sarcoma tumors.

PMID- 4361374
TI  - Granular cell myoblastoma of the esophagus.

PMID- 4361375
TI  - [Various aspects of the problem of chromosomal DNA replication].

PMID- 4361377
TI  - [Circadian rhythm of cortisol secretion in patients with hypertension].

PMID- 4361376
TI  - [Ultrastructural location of the enzyme systems of the cell nucleus].

PMID- 4361379
TI  - [Electrophoresis of serum lipoproteins on cellulose acetate foils].

PMID- 4361378
TI  - [Diet therapy in hyperlipoproteinemias].

PMID- 4361380
TI  - Propagation of some common viruses in human embryonic brain cells.

PMID- 4361381
TI  - Clear-cell carcinoma of the liver. A clinicopathologic study of 13 patients.

PMID- 4361382
TI  - Acquired cytomegalovirus infection presenting as viral endometritis.

PMID- 4361383
TI  - Non-chromaffin paragangliomatosis manifesting as a cold thyroid nodule.

PMID- 4361384
TI  - Proceedings: Carcinoma of the soft palate and uvula.

PMID- 4361385
TI  - Proceedings: Serum alpha-fetoprotein and Ga67 citrate uptake in hepatoma.

PMID- 4361386
TI  - Proceedings: Arteriography in insulinoma.

PMID- 4361387
TI  - Multiple primary bronchogenic carcinoma with a review of the literature.

PMID- 4361388
TI  - Ozone effect on respiratory deposition of vesicular stomatitis virus aerosols.

PMID- 4361390
TI  - Pulmonary infections complicating treatment of multiple sclerosis. Occurrence
      with administration of corticotropin or adrenal steroids.

PMID- 4361389
TI  - Beclomethasone in childhood asthma.

PMID- 4361391
TI  - Reye syndrome. An association with type I vaccine-like poliovirus.

PMID- 4361392
TI  - Parainfluenza, histocompatibility, and multiple sclerosis. Association of
      parainfluenza antibodies and histocompatibility types in MS and optic neuritis.

PMID- 4361393
TI  - Genetic heterogeneity of hereditary sensory neuropathy.

PMID- 4361394
TI  - MU-chain disease in an African patient.

PMID- 4361395
TI  - Hemoglobin Duarte: (alpha2beta2 62(E6)Ala leads to Pro): a new unstable
      hemoglobin with increased oxygen affinity.

PMID- 4361396
TI  - [The electron spin resonance (ESR) study in experimental and applied bone
      research].

PMID- 4361397
TI  - Importance of central catecholaminergic neurones in the development and
      maintenance of renal hypertension.

PMID- 4361398
TI  - Spironolactone and amiloride in the treatment of low renin hyperaldosteronism and
      related syndromes.

PMID- 4361399
TI  - Metabolic clearance rate of angiotensin II in arterial hypertension.

PMID- 4361400
TI  - Synthesis of renin inhibitors.

PMID- 4361401
TI  - Renin release and renal vasomotor changes during stimulation of the brain stem in
      the cat.

PMID- 4361403
TI  - Angiotensin-salt hypertension.

PMID- 4361402
TI  - Effects of angiotensin II on adenylcyclase activity, phosphodiesterase activity
      and on the level of cyclic AMP in rat uterus.

PMID- 4361404
TI  - Experimental studies on the mechanism of adrenocorticotrophic hormone-induced
      hypertension in the sheep.

PMID- 4361406
TI  - Oral contraceptives and hypertension.

PMID- 4361405
TI  - Plasma renin activity and plasma renin substrate in hypertension associated with
      steroid excess.

PMID- 4361407
TI  - Diseases and surgery of the nose.

PMID- 4361408
TI  - Hormonal profiling in the diagnosis and treatment of essential hypertension.

PMID- 4361409
TI  - Effects of diphenylhydantoin upon glucose-induced insulin secretion in three
      patients with insulinoma.

PMID- 4361410
TI  - Insulin receptors in human and animal placental tissue.

PMID- 4361411
TI  - Cytologic and functional changes in the adrenal cell culture from a human fetus
      under the action of o, p1-DDD. I. Morphological study.

PMID- 4361412
TI  - Cytologic and functional changes in the adrenal cell culture from a human fetus
      under the action of o, p1-DDD. II. Study of corticosteroid production.

PMID- 4361414
TI  - Affinity chromatography on immobilised adenosine 5'-monophosphate. 3. The binding
      of glycerokinase and lactate dehydrogenase in relation to column geometry and
      dynamics.

PMID- 4361413
TI  - Comparative studies on the template-initiator requirements of the chick-embryo
      DNA polymerase I and the avian-myeloblastosis-virus DNA polymerase.

PMID- 4361415
TI  - Affinity chromatography on immobilised adenosine 5'-monophosphate. 4. Variation
      of the binding of dehydrogenases and kinases with pH.

PMID- 4361416
TI  - Affinity chromatography on immobilised adenosine 5'-monophosphate. 5. Some
      applications of the influence of temperature on the binding of dehydrogenases and
      kinases.

PMID- 4361417
TI  - Animal DNA-dependent RNA polymerases. Studies on the reaction parameters of
      transcription in vitro of Simian virus 40 DNA by mammalian RNA polymerases AI and
      B.

PMID- 4361418
TI  - Animal DNA-dependent RNA polymerases. Analysis of the RNAs synthesized on Simian
      virus 40 superhelical DNA by mammalian RNA polymerases AI and B.

PMID- 4361419
TI  - Animal DNA-dependent RNA polymerases. Studies on the binding of mammalian RNA
      polymerases AI and B to Simian virus 40 DNA.

PMID- 4361420
TI  - Inhibition of spontaneous aggregation by wheat germ agglutinin in suspensions of
      BALB-C-3T3 and BHK21 tissue culture fibroblasts.

PMID- 4361421
TI  - Synthesis of DNA-binding protein in WI-38 cells stimulated to synthesize DNA by
      medium replacement.

PMID- 4361422
TI  - Thymidine transport by Novikoff rat hepatoma cells synchronized by double
      hydroxyurea treatment.

PMID- 4361423
TI  - Cyclic AMP dependent regulation of mitosis in human lymphoid cells.

PMID- 4361424
TI  - Tes and HEPES buffers in mammalian cell cultures and viral studies: problem of
      carbon dioxide requirement.

PMID- 4361425
TI  - Myogenesis in vitro. Enhancement by dibutyryl cAMP.

PMID- 4361426
TI  - Chromatin fractionation of normal and virus-transformed cells in culture.

PMID- 4361427
TI  - Chemical labeling and freeze-fracture studies on the localization of rhodopsin in
      the rod outer segment disk membrane.

PMID- 4361428
TI  - Pneumoconiosis.

PMID- 4361429
TI  - Prolonged administration of Penicillium viridicatum to mice: preliminary report
      of carcinogenicity.

PMID- 4361430
TI  - Corticosteroid therapy in corneal disease. I.

PMID- 4361431
TI  - Treatment of corneal ulcers with collagenase inhibitors.

PMID- 4361432
TI  - Current therapy of herpes simplex virus infection of the cornea.

PMID- 4361433
TI  - In vitro phosphate transport in chick ileum: effect of cholecalciferol, calcium,
      sodium and metabolic inhibitors.

PMID- 4361435
TI  - Fluctuation of the nucleotide pools of flavinogenic and nonflavinogenic strains
      of Eremothecium ashbyii grown in the presence of purines.

PMID- 4361434
TI  - Investigations on serum lipid components and serum vitamin E in iron deficiency
      anemia.

PMID- 4361436
TI  - Cyclic adenosine 3':5'-monophosphate and protein kinase levels in developing
      bovine spermatozoa.

PMID- 4361438
TI  - Letter: Estrogen binding in breast cancer.

PMID- 4361439
TI  - Inclusion-body beta-thalassemia trait. A form of beta thalassemia producing
      clinical manifestations in simple heterozygotes.

PMID- 4361440
TI  - Prevention of gestational trophoblastic disease by use of actinomycin D in molar
      pregnancies.

PMID- 4361437
TI  - [Calcium absorption in health and disease. II. Syndromes of imparied calcium
      absorption (author's transl)].

PMID- 4361442
TI  - Arrhenoblastomas and associated ovarian pathology.

PMID- 4361441
TI  - Arrhenoblastoma associated with adrenal androgenic hyperfunction.

PMID- 4361443
TI  - A new oral amoebicid (RO 7-0207) in the treatment of intestinal amoebiasis.

PMID- 4361444
TI  - [Interplay of molecular mechanism of biological reactions and the physical
      parameters of "reaction-fields"--a discussion concerning the primary processes of
      photosynthesis].

PMID- 4361445
TI  - [Recent contributions to the study of arterial hypertension].

PMID- 4361446
TI  - Chemistry and biologic activity of the complement system.

PMID- 4361447
TI  - Synthesis and metabolism of complement proteins.

PMID- 4361448
TI  - Editorial: Implications of equine virus abortion.

PMID- 4361449
TI  - [Ultrastructure of hyperplastic and adenomatous corticotrophic cells in Cushing's
      syndrome of hypothalamic-hypophyseal origin (author's transl)].

PMID- 4361450
TI  - Cell killing by viruses. I. Comparison of cell-killing, plaque-forming, and
      defective-interfering particles of vesicular stomatitis virus.

PMID- 4361451
TI  - Morphologic revertants of murine sarcoma virus transformed nonproducer BALB-3T3:
      selective techniques for isolation and biologic properties in vitro and in vivo.

PMID- 4361452
TI  - Conditional lethal mutants of vesicular stomatitis virus. I. Phenotypic
      characterization of single and double mutants exhibiting host restriction and
      temperature sensitivity.

PMID- 4361453
TI  - Conditional lethal mutants of vesicular stomatitis virus. II. Synthesis of virus
      specific polypeptides in nonpermissive cells infected with "RNA-" host-restricted
      mutants.

PMID- 4361454
TI  - The molecular size of the herpes simplex virus type 1 genome.

PMID- 4361455
TI  - Antigens specified by herpesviruses. 3. Viral-induced nuclear polypeptides.

PMID- 4361456
TI  - Interferon production by individual cells.

PMID- 4361457
TI  - Identification of biological activities of paramyxovirus glycoproteins.
      Activation of cell fusion, hemolysis, and infectivity of proteolytic cleavage of
      an inactive precursor protein of Sendai virus.

PMID- 4361458
TI  - An improved murine leukemia virus immunofluorescence assay.

PMID- 4361459
TI  - Structure of the Mengo virion. I. Polypeptide and ribonucleate components of the
      virus particle.

PMID- 4361460
TI  - Isolation, complementation and preliminary phenotypic characterization of
      temperature-sensitive mutants of herpes simplex virus type 2.

PMID- 4361461
TI  - In vitro association of vesicular stomatitis virus proteins with purified HeLa
      and erythrocyte plasma membranes.

PMID- 4361462
TI  - Therapy of herpes simplex with heat inactivated Herpes virus hominis type 1 and
      type 2.

PMID- 4361463
TI  - [Attempted disposal of an infant's body by cremation (author's transl)].

PMID- 4361464
TI  - Effect on steroid metabolism of STC-407 and cyproterone acetate in female
      hirsutism.

PMID- 4361465
TI  - Plasma free fatty acid and acute vascular injury.

PMID- 4361466
TI  - Cholangiocarcinoma with hypercalcemia--a case report studied by electron
      microscope and radioimmunoassay.

PMID- 4361468
TI  - Determination of the amount of bone in the metacarpal.

PMID- 4361467
TI  - Diet and bone rarefaction in old age.

PMID- 4361470
TI  - Should we always keep controlling?

PMID- 4361469
TI  - Editorial: Viruses and arteriosclerosis.

PMID- 4361471
TI  - Finite level models of biological systems.

PMID- 4361472
TI  - [Value of selective angiography of the external carotid in the diagnosis of
      tumors of the tympanic glomus].

PMID- 4361474
TI  - [The ultrastructure of human synovial sarcoma cells].

PMID- 4361473
TI  - The radiological importance of soft-tissue lesions related to the skeleton.

PMID- 4361475
TI  - Glioblastoma of the optic chiasm.

PMID- 4361476
TI  - Cullen's sign, a feature in liver disease.

PMID- 4361477
TI  - [Value of bronchoscopy after hemoptysis].

PMID- 4361478
TI  - An aphasic syndrome in children.
AB  - The paper presents case reports of nine children, all of whom had severe
      disturbances of language function of abrupt or gradual onset. Seizures occurred
      in seven of the children and all nine had EEG abnormalities.There was no apparent
      correlation between the seizures, the EEG changes and the aphasia. One patient
      had a brain biopsy performed at another hospital and the tissue was said to be
      normal. The cause of the abnormal language function is unknown. Five of the
      children failed to acquire normal speech subsequently. Three of the four children
      who made a complete recovery were treated with steroids.

PMID- 4361479
TI  - The structure of a dextran produced by Leuconostoc mesenteroides NRRL B-1397: the
      linkages and length of the branches.

PMID- 4361480
TI  - Comparison of pelvic osteotomies for the surgical correction of the congenital
      hip.

PMID- 4361481
TI  - The role of the kidney and vitamin D metabolism in health and disease.

PMID- 4361482
TI  - Proceedings: The effects of exogenous parathyroid hormone on circulating
      adenosine 3':5' monophosphate in man.

PMID- 4361483
TI  - Proceedings: Unsaturated fat and plasma triglyceride metabolism in man.

PMID- 4361484
TI  - The pressor response to intravenously infused angiotensin II: correlation with
      plasma renin activity.

PMID- 4361485
TI  - Proceedings: Inhibition of adenyl cyclase by a bacterial exotoxin.

PMID- 4361486
TI  - Competitive protein-binding assay for 25-hydroxycholecalciferol.

PMID- 4361487
TI  - Action of angiotensin antagonists and antiserum upon the pressor response to
      renin: further evidence for the local generation of angiotensin II.

PMID- 4361488
TI  - The charade of poverty funding for community mental health centers.

PMID- 4361489
TI  - Proceedings: Molecular aspects in comparative endocrinology.

PMID- 4361490
TI  - A serological study on the occurrence of some respiratory infections in Fiji.

PMID- 4361491
TI  - Short-term heroin detoxification on an outpatient basis.

PMID- 4361492
TI  - Corneal ulceration and the serum antiproteases. I. Alpha 1-antitrypsin.

PMID- 4361493
TI  - Fibroblast collagenase partial purification and characterization.

PMID- 4361494
TI  - Corneal toxicity of collagenase inhibitors.

PMID- 4361495
TI  - The "new" vegetarians. Group affiliation and dietary strictures related to
      attitudes and life style.

PMID- 4361496
TI  - Vitamin E: relationship to thyroxine in man.

PMID- 4361497
TI  - An experiment in liaison psychiatry to a community health center.

PMID- 4361498
TI  - Sudden infant death syndrome: an epidemiologic study.

PMID- 4361499
TI  - A biologically active insulin analog with an enlarged intrachain cyclic system.

PMID- 4361500
TI  - Susceptibility of the VERO line of African green monkey kidney cells to human
      enteroviruses.
AB  - The relative susceptibility of VERO cells and primary rhesus monkey kidney cells
      to 47 prototype strains of human enteroviruses is described. Of these strains,
      types 4, 14, 16, 17, 18, 21, 31 and 34 and Coxsackie virus A 9 failed to cause
      CPE in the VERO cells whilst only one, echovirus type 34, failed to cause CPE in
      the monkey kidney cells.A comparison is given of the efficiency of the two cell
      cultures for enterovirus isolation from clinical material. Results show that VERO
      cells are as useful as primary monkey kidney for the isolation of Coxsackie B
      viruses but less satisfactory for isolating echoviruses. They are satisfactory
      for the isolation of single types of poliovirus and appear to be more
      satisfactory than primary monkey kidney cells for the isolation of mixtures of
      polioviruses. The identification of enteroviruses by neutralization tests in VERO
      cells is successful.

PMID- 4361501
TI  - The airborne excretion by pigs of swine vesicular disease virus.
AB  - The air of loose-boxes holding pigs affected with swine vesicular disease was
      sampled for virus. In the multistage impinger virus to a titre of 10(2.6) TCID 50
      was associated with particles greater than 6 mum., 10(1.6) with particles 3-6
      mum. and 10(1.4) or less with particles less than 3 mum. In the noses of workers
      in contact with the pigs for periods not less than 5 min., virus to a titre of
      10(2.4) TCID 50 was found. Virus was recovered from the air for 2-3 days during
      the disease and maximum titre in pigs infected by injection or by contact
      occurred on the second to third day after generalization of the lesions. The
      amounts of virus were about 160-fold less than those recovered from pigs affected
      with foot-and-mouth disease, and the quantity and time of excretion suggest that
      the source of swine vesicular disease virus in the aerosol may be from the
      lesions and skin rather than from the respiratory tract.

PMID- 4361503
TI  - Arbovirus serology in North Dakota mule and white-tailed deer.

PMID- 4361502
TI  - Antibody responses in patients with farmer's lung disease to antigens from
      Micropolyspora faeni.
AB  - Three purified cell-wall glycoprotein antigens, a, b and c, sensitive to sodium
      periodate and resistant to pronase, were extracted from mycelium of
      Micropolyspora faeni with aqueous phenol or trichloracetic acid. Pronase
      sensitive, sodium periodate-resistant protein antigens were extracted from
      mycelium with aqueous phenol. Immunoelectrophoresis was a critical method of
      assessing purity of preparation.Antibodies to glycoprotein antigens only occurred
      in clinically defined cases of farmer's lung disease, whereas antibodies to
      protein antigens also occurred in symptomless farmers. Precipitins to a occurred
      in all cases of farmer's lung disease, and this antigen was isolated and
      purified.Fractionation of pooled sera from cases of farmer's lung disease showed
      that precipitins were IgG globulins, whereas latex-agglutinating antibodies were
      IgG, IgA and especially IgM globulins. It is suggested that farmer's lung may
      involve a cytotoxic type II reaction, in which glycoproteins adsorbed to tissue
      cells react with IgG, IgA and IgM immunoglobulins in the presence of complement,
      causing cellular damage.

PMID- 4361504
TI  - A study of reproduction, disease and physiological blood and serum values in
      Idaho elk.

PMID- 4361505
TI  - Vaccination of American bison against Pasteurella multocida serotype 2 infection
      (Hemorrhagic septicemia).

PMID- 4361506
TI  - Neutralization of channel catfish virus by serum of channel catfish.

PMID- 4361507
TI  - Electron microscopy of the virus of oral papillomatosis in the coyote.

PMID- 4361508
TI  - Cholesterol metabolism in the rat sensitive to high cholesterol diet.

PMID- 4361509
TI  - A fatal case of type 2 herpes simplex virus infection in a newborn.

PMID- 4361510
TI  - Changes in back-transplantability by fluid-suspension culture and by long-term of
      cultivation of two tissue culture cell strains, JTC-1 and JTC-2, originated from
      rat ascites hepatoma AH-130.

PMID- 4361511
TI  - Humoral cytotoxic factor in isograft immunity against azo-dye induced hepatoma.

PMID- 4361512
TI  - [Use of the oil contrast media in the radiography of the retrosternal lymph nodes
      (survey of the foreign literature and our own investigations)].

PMID- 4361514
TI  - [Cancer of the rhinopharynx. A rare cancer].

PMID- 4361513
TI  - Primary hyperparathyroidism: clinical and biochemical features.

PMID- 4361517
TI  - Electron microscopy of bluetongue virus RNA.

PMID- 4361515
TI  - Foot-and-mouth disease in the african elephant (Loxodonta africana).

PMID- 4361518
TI  - Total decompression of the facial nerve in osteopetrosis (marble bone disease
      morbus Albers-Schonberg).

PMID- 4361521
TI  - Certain examples of application of ascorbate in biochemical investigations.

PMID- 4361523
TI  - Hodgkin's disease: considerable progress and more to be achieved.

PMID- 4361522
TI  - [Active metabolites of vitamin D].

PMID- 4361524
TI  - Electron microscopy of chlorphentermine lung.

PMID- 4361525
TI  - Plasma cortisol and the use of hydrocortisone in the treatment of status
      asthmaticus.

PMID- 4361527
TI  - [Reproduction of Rous sarcoma in chicks].

PMID- 4361526
TI  - Granular cell myoblastoma of the oesophagus.

PMID- 4361528
TI  - Studies in cholestasis of pregnancy with special reference to lipids and
      lipoproteins.

PMID- 4361530
TI  - Nonhuman primates in viral oncology.

PMID- 4361529
TI  - Cyclic nucleotide phosphodiesterases.

PMID- 4361531
TI  - Comparison of the 14-C-putrescine assay with the NADH test for the determination
      of diamine oxidase: description of a standard procedure with a high precision and
      an improved accuracy.

PMID- 4361532
TI  - Intestinal diamine oxidase: isolation, substrate specificity and
      pathophysiological significance.

PMID- 4361533
TI  - Copper heterogeneity in pig kidney histaminase. An EPR study on the effect of
      substrate, guanidine and mersalyl.

PMID- 4361534
TI  - The intimal proliferation in aortic-coronary saphenous vein grafts. Light and
      electron microscopic studies.

PMID- 4361535
TI  - Intrauterine virus infections and congenital heart disease.

PMID- 4361536
TI  - Cyclic adenosine monophosphate and clinical medicine. I.

PMID- 4361537
TI  - Effects of angiotensin I and angiotensin II on renal blood flow in sheep.

PMID- 4361538
TI  - Plasma 17-hydroxycorticosteroids and growth hormone during defense reactions.

PMID- 4361539
TI  - Determinants of systemic hydraulic power in unanesthetized dogs.

PMID- 4361540
TI  - Effect of melanotropic peptides on protein synthesis in mouse brain.

PMID- 4361541
TI  - An antimelanotropic protein in human cerebrospinal fluid.

PMID- 4361543
TI  - Orbital space-occupying lesions. Four decades of Eye Hospital reports.

PMID- 4361542
TI  - Enzyme changes in diabetes mellitus.

PMID- 4361544
TI  - Oat cell carcinoma of the larynx.

PMID- 4361545
TI  - Isolation and lipid composition of spinach chloroplast envelope membranes.

PMID- 4361546
TI  - Purification and characterization of the Novikoff hepatoma glycogen phosphorylase
      and its relations to a fetal form.

PMID- 4361547
TI  - On the mechanism of a calcium-associated defect of oxidative phosphorylation in
      progessive muscular dystrophy.

PMID- 4361548
TI  - Simultaneous measurement of oxidative phosphorylation and adenylate kinase in
      plant mitochondria.

PMID- 4361550
TI  - Homotropic regulation of dihydrolipoyl dehydrogenase from bovine kidney.

PMID- 4361549
TI  - Structural requirements for the formation of ordered lipid multibilayers--a spin
      probe study.

PMID- 4361551
TI  - An assessment of some molecular parameters of mevalonate kinase from plant and
      animal sources.

PMID- 4361552
TI  - Enzymes of serine biosynthesis in Rhodopseudomonas capsulata.

PMID- 4361553
TI  - Respiratory changes induced by guanidines and cations in submitochondrial
      particles.

PMID- 4361554
TI  - The oxidation-reduction potentials of electron carriers in chloroplast
      photosystem I fragments.

PMID- 4361555
TI  - Cholesterol uptake from doubly-labeled alpha-lipoproteins by cells in tissue
      culture.

PMID- 4361556
TI  - The molecular reorganization of lipid bilayers by osmium tetroxide. A spin-label
      study of orientation and restricted y-axis anisotropic motion in model membrane
      systems.

PMID- 4361557
TI  - Enzymatic dehydrogenation of steroids by beta-hydroxysteroid dehydrogenase in a
      two-phase system.

PMID- 4361558
TI  - The mechanism of the diaphorase reaction catalyzed by glyceraldehyde-3-phosphate
      dehydrogenase.

PMID- 4361559
TI  - Aspects of Epstein-Barr virus infection in childhood.

PMID- 4361561
TI  - Neuro-vestibular correlates in cerebral hemispheric lesions.

PMID- 4361560
TI  - Neuro-audiological correlates in cerebral hemisphere lesions. Temporal and
      parietal lobe tumors.

PMID- 4361562
TI  - Hearing levels in Nigerian ataxic neuropathy.

PMID- 4361563
TI  - Depolarization-evoked accumulation of cyclic AMP in brain slices: inhibition by
      exogenous adenosine deaminase.

PMID- 4361564
TI  - Radiosensitivity and the ascorbic acid electron spin resonance doublet.

PMID- 4361565
TI  - Very low density lipoprotein "remnant" particles: uptake by aortic smooth muscle
      cells in culture.

PMID- 4361566
TI  - Effects of insulin on gluconeogenesis and cyclic AMP levels in perfused livers
      from diabetic rats.

PMID- 4361567
TI  - Effects of adrenalectomy and glucocorticoid replacement on gluconeogenesis in
      perfused livers from diabetic rats.

PMID- 4361568
TI  - Vitamin D metabolites. Specific binding by rat intestinal cytosol.

PMID- 4361569
TI  - The role of calcium in fly salivary gland secretion analyzed with the ionophore A
      23187.

PMID- 4361570
TI  - The development and present status of ultrasonic encephalography.

PMID- 4361571
TI  - Renal function during and after anaesthesia and surgery: significance for water
      and electrolyte management.

PMID- 4361572
TI  - Chlamydial infections of the cervix.

PMID- 4361573
TI  - Chlamydia A in the female genital tract.

PMID- 4361574
TI  - Ultrastructural characteristics of Trichomonas vaginalis. An electron
      microscopical study.

PMID- 4361576
TI  - The role of infection in the morbidity of asthmatic children admitted to
      hospital.

PMID- 4361575
TI  - Sexually transmitted diseases. Extract from the Annual Report of the Chief
      Medical Officer of the Department of Health and Social Security for the year
      1972.

PMID- 4361577
TI  - [Effects of toxic fumes on humans produced by welding. Detection of free radicals
      in gases from arc welding under argon].

PMID- 4361578
TI  - [Phalloides poisoning. Actual clinical, pathogenic and therapeutic instances].

PMID- 4361579
TI  - Proceedings: Aspects of EB virus infection.

PMID- 4361580
TI  - Proceedings: Virological aspects.

PMID- 4361581
TI  - Proceedings: EB virus and other diseases.

PMID- 4361582
TI  - Gentamicin:adenine mononucleotide transferase: partial purification,
      characterization, and use in the clinical quantitation of gentamicin.

PMID- 4361584
TI  - Three Yugoslav herpes simplex viruses: biologic and antigenic properties and
      formation of giant cells in vitro by a cervical isolate.

PMID- 4361583
TI  - Cyclic production of vesicular stomatitis virus caused by defective interfering
      particles.

PMID- 4361585
TI  - Editorial: Recent contributions to the mechanism of action and clinical relevance
      of erythropoietin.

PMID- 4361586
TI  - The lymphoreticular system and interferon production.

PMID- 4361587
TI  - Studies on the function of cell membrane. 8th report. Binding of cytochrome c to
      liver plasma membrane and microsome in CCl4-poisoned rats.

PMID- 4361588
TI  - Studies on the function of cell membrane. 9th report. Protective action of sodium
      taurine N-carbodithioate (TDT) against CCl4-induced biochemical changes in liver
      cell membrane of rats.

PMID- 4361589
TI  - Participation of muscarinic receptors on splanchnic-adrenal transmission in the
      rat.

PMID- 4361590
TI  - Potentiation of the contractile response of isolated aortae to transmural
      stimulation by angiotensin.

PMID- 4361591
TI  - Effect of cytochrome c on carbon tetrachloride damage to the liver.

PMID- 4361592
TI  - Effects of low concentrations of lithium chloride on adrenergic transmission in
      the isolated atria of rabbits.

PMID- 4361594
TI  - [Acupuncture analgesia in cats. A preliminary report].

PMID- 4361593
TI  - Anti-oxytocin actions of papaverine, aspaminol and isoprenaline on the rat uterus
      and intracellular cyclin adenosine 3,5-monophosphate level.

PMID- 4361595
TI  - The role of cyclic nucleotides in visual excitation.

PMID- 4361596
TI  - The construction and use of quartz fiber fish pole balances.

PMID- 4361598
TI  - [Biochemical study of various mucopolysaccharide constituents and glycoproteins
      of serum and of several organs of rats treated with potassium perchlorate].

PMID- 4361599
TI  - Action of a serum protein in coupling excitation contraction of heart papillary
      muscle.

PMID- 4361597
TI  - Oxidation states of peroxidase.

PMID- 4361601
TI  - Mycobacterium fortuitum abscess related to surgery, malignancy, and a tight
      girdle.

PMID- 4361600
TI  - [Quantitative correlation of structure and function on biomembranes (author's
      transl)].

PMID- 4361602
TI  - The treatment of ileocolitis with ACTH and prednisone: immediate and prolonged
      effect.

PMID- 4361603
TI  - Bronchiolar-alveolar carcinoma of the lung.

PMID- 4361604
TI  - Current therapy of thyroid nodules.

PMID- 4361605
TI  - Medullary carcinoma of the thyroid gland: use of biochemical parameters in
      detection and surgical management of the tumor.

PMID- 4361606
TI  - Endocrine surgery in children.

PMID- 4361607
TI  - Surgical management of the Zollinger-Ellison syndrome.

PMID- 4361608
TI  - Surgical considerations in gynecologic endocrine disorders.

PMID- 4361609
TI  - Radical surgery of tumors of the thalamus, hypothalamus, and third ventricle
      area.

PMID- 4361610
TI  - The ultrastructure of the accessory sex organs of the male rat. II. The post
      castration involution of the ventral, lateral and the dorsal prostate.

PMID- 4361611
TI  - The ultrastructure of the accessory sex organs of the male rat. 3. The post
      castration involuation of the coagulating gland and the seminal vesicle.

PMID- 4361612
TI  - Ultrastructure and functional aspects of the nucleus infundibularis ventralis in
      the green frog, Rana esculenta.

PMID- 4361613
TI  - Electron microscopical studies on the structure, phagocytic properties, and
      peroxidatic activity of resident and exudate peritoneal macrophages in the guinea
      pig.

PMID- 4361615
TI  - [The histochemical behaviour of the 17-beta-hydroxysteroid-dehydrogenase in the
      human placenta after normal acid and pathological gestation (author's transl)].

PMID- 4361614
TI  - Effect of denaturation on muscle proteins as studied by Epr.

PMID- 4361616
TI  - Histoenzymic studies of the central nervous system in tri-ortho-cresyl phosphate
      poisoning.

PMID- 4361617
TI  - [Enzyme histochemical investigations on the brain of rats after implantation of
      cobalt pellets (author's transl)].

PMID- 4361618
TI  - Influence of adrenocorticotropic hormone on red cell mass and body composition of
      the hypophysectomized rat.

PMID- 4361619
TI  - Hydrosmotic effect of angiotensin II in the toad bladder: role of cyclic AMP.

PMID- 4361620
TI  - Protein synthesis by isolated spermatozoa from cauda and caput epididymis of rat.

PMID- 4361621
TI  - Isolation of proteins by gel filtration in 6M guanidinium chloride: application
      to RNA tumor viruses.

PMID- 4361622
TI  - Analysis of steroids in biological fluids by computer-aided gas-liquid
      chromatography--mass spectrometry.

PMID- 4361623
TI  - The electrophoretic separation of nucleoside-5'-phosphates from nucleoside
      trialcohol monophosphates, and its application to the identification of 3'-end
      groups.

PMID- 4361624
TI  - Fifty years with viruses (Christopher H. Andrewes).

PMID- 4361625
TI  - [Regulation of immunologic tumor-host relations in virus-induced mammary
      carcinoma of the mouse].

PMID- 4361626
TI  - [In-vivo effectivity of heterologous rabbit antisera against mouse leukemias].

PMID- 4361627
TI  - New isothiazole derivatives. II. Cytotoxicity and antiviral activity in tissue
      cultures.

PMID- 4361628
TI  - DNA in heterochromatin cytophotometric pattern recognition image analysis among
      cell nuclei in duct epithelium and in carcinoma of the human breast.

PMID- 4361630
TI  - [Synovialosarcoma: apropos of 2 cases].

PMID- 4361629
TI  - [Electrodiagnosis of retinal diseases (retinal rest and action potentials].

PMID- 4361631
TI  - [From viral hepatitis to primary liver cancer: apropos of an observation of a
      direct connection].

PMID- 4361632
TI  - Comparison of hemodynamic responses to exercise in hypertensive patients and in
      healthy subjects given angiotensin.

PMID- 4361633
TI  - Exogenous hormones in pregnancy.

PMID- 4361634
TI  - Gynecologic endocrine disorders in childhood and adolescence.

PMID- 4361635
TI  - Multihormonal regulation of hepatic histidase during postnatal development.

PMID- 4361636
TI  - Cellular differentiation and isozymes of branched-chain amino acid transaminase.

PMID- 4361637
TI  - Development of disaccharidase and phosphatase activities in the intestine and
      liver.

PMID- 4361638
TI  - Control of rat liver phosphorylase, glucose-6-phosphatase and phosphoenolpyruvate
      carboxykinase activities by insulin and glucagon during the perinatal period.

PMID- 4361639
TI  - The regulation of liver development by birth.

PMID- 4361640
TI  - Nucleotide supply of the developing animal: role of the so-called 'salvage
      pathways'.

PMID- 4361641
TI  - Development of intestinal function in mammals.

PMID- 4361642
TI  - The developmental formation of enzymes involved in glycogen metabolism.

PMID- 4361643
TI  - The regulation of phosphoenolpyruvate carboxykinase in fetal rat liver.

PMID- 4361645
TI  - A sequence of 54 nucleotides from the A-protein cistron of coliphage-R17 RNA.

PMID- 4361644
TI  - The effects of bases and nucleosides on the intracellular contents of nucleotides
      and 5-phosphoribosyl 1-pyrophosphate in Escherichia coli.

PMID- 4361646
TI  - Studies with analogues of nicotinamide adenine dinucleotide.

PMID- 4361648
TI  - Early chromosome changes in diploid Chinese hamster cells after infection with
      Simian virus 40.

PMID- 4361647
TI  - Hydrolysis of the cyclic 3':5'-monophosphates of adenosine and guanosine by rat
      pancreas.

PMID- 4361649
TI  - Kinetics of the anti-tumor delayed hypersensitivity response in mice with
      progressively growing tumors: stimulation followed by specific suppression.

PMID- 4361650
TI  - Properties of flat variants of murine sarcoma virus transformed non-producer
      cells isolated after high-temperature passage.

PMID- 4361652
TI  - Kinetics of uptake of 2-deoxy-D-glucose and 2-aminoisobutyric acid in chemically
      transformed cells.

PMID- 4361651
TI  - Differences in the surface mobility between normal and SV40-, polyoma- and
      adenovirus-transformed hamster cells.

PMID- 4361653
TI  - Syndactyly. A review of the literature.

PMID- 4361654
TI  - Proteolipids. VI. The dual role of phospholipid in cytochrome oxidase reaction.

PMID- 4361655
TI  - Spin-labelling studies of fragmented sarcoplasmic reticulum.

PMID- 4361657
TI  - [Cancer of the corpus uteri].

PMID- 4361658
TI  - Vinblastine in the treatment of carcinoma of liver.

PMID- 4361656
TI  - The role of adenosine 3',5'-cyclic monophosphate in the regulation of mammalian
      cell division.

PMID- 4361659
TI  - Functional anion binding sites in dogfish M4 lactate dehydrogenase.

PMID- 4361660
TI  - Fine structure of the axon collaterals of Huber in frog spinal ganglia.

PMID- 4361661
TI  - Hypermyoinositolemic polyneuropathy in rats. A possible mechanism for uremic
      polyneuropathy.

PMID- 4361663
TI  - Somatosensory evoked responses to mechanical stimulation in normal subjects and
      in patients with neurological disorders.

PMID- 4361662
TI  - Multiple system atrophies. A neuropathological and neurochemical study.

PMID- 4361664
TI  - Paralysis periodica paramyotonica. A clinical and neurophysiological study.

PMID- 4361665
TI  - Concentrically laminated membranous inclusions in myofibres of Dyggve-Melchior
      Clausen syndrome.

PMID- 4361666
TI  - Polyneuropathy in Waldenstrom's macroglobulinaemia.

PMID- 4361667
TI  - Effects of the microbial environment on drug resistance.

PMID- 4361669
TI  - [Risk factor night work and shift work].

PMID- 4361668
TI  - [Studies on the mechanism of the pressor effect of mineralocorticoids. I.
      Influence of 9 alpha-fluorohydrocortisone on the pressor effect of tyramine,
      noradrenaline, and angiotensin, on blood volume, and on plasma renin
      concentration (author's transl)].

PMID- 4361670
TI  - New roles for ascorbic acid.

PMID- 4361671
TI  - [Best methods for the detection of Staphylococci in feed mixtures. I. Suitability
      of various media for determination of titer].

PMID- 4361672
TI  - D-glyceraldehyde-3-phosphate dehydrogenase: three-dimensional structure and
      evolutionary significance.
AB  - A 3.0-A resolution electron density map of lobster glyceraldehyde-3-phosphate
      dehydrogenase (EC 1.2.1.12) was computed. The essentially single isomorphous
      replacement map was very substantially improved by averaging subunits. NAD binds
      in an open conformation at sites close to subunit interfaces. The coenzyme
      binding portion of the enzyme has almost the same fold as the corresponding
      portion of lactate dehydrogenase (EC 1.1.1.27). The presence of this structure in
      the five enzymes, analyzed so far, that use nucleotide coenzymes might indicate a
      fundamental primordial structural element.

PMID- 4361673
TI  - Programming of cells for death under experimental conditions: relevance to the
      tumor problem.
AB  - An attempt was made in this study to determine more precisely the nature of the
      factors that are involved in the programming of cells for a form of terminal
      cellular differentiation that results in death. These studies demonstrated that
      both the cytokinesins, which are potent inhibitors of plant and animal adenosine
      3':5'-cyclic monophosphate phosphodiesterases, and 8-bromoadenosine 3':5'-cyclic
      monophosphate, which is a stable, biologically active form of adenosine 3':5'
      cyclic monophosphate, are highly effective in encouraging differentiation of
      parenchyma cells into tracheary elements with accompanying death. Since adenosine
      3':5'-cyclic monophosphate and theophylline when used together were also
      effective, the results reported here suggest that adenosine 3':5'-cyclic
      monophosphate is somehow importantly involved in the conversion of parenchyma
      cells into tracheary elements in this system. The possible significance to the
      tumor problem generally of the programming of cells for terminal differentiation,
      with or without resulting death, is discussed.

PMID- 4361674
TI  - Integration of deoxyribonucleic acid specific for Rous sarcoma virus after
      infection of permissive and nonpermissive hosts.
AB  - A relatively simple but stringent technique was developed to detect the
      integration of virus-specific DNA into the genomes of higher organisms. In both
      permissive (duck) and nonpermissive (mammalian) cells which normally contain no
      nucleotide sequences specific for Rous sarcoma virus, transformation by the virus
      results in the appearance of DNA specific for Rous sarcoma virus covalently
      integrated into strands of host-cell DNA containing reiterated sequences. Early
      after infection of mouse or duck cells by Rous sarcoma virus, unintegrated DNA
      specific for the virus can be demonstrated.

PMID- 4361675
TI  - A mammalian cell mutant with a temperature-sensitive leucyl-transfer RNA
      synthetase.
AB  - A cell mutant of the Chinese hamster ovary line, which is temperature sensitive
      for protein synthesis, is specifically defective in vivo in its ability to charge
      tRNA with leucine. Cytoplasmic extracts exhibited temperature-sensitive leucyl
      tRNA synthetase activity. It is, therefore, highly likely that the mutant has a
      structural alteration in leucyl-tRNA synthetase. The low leakiness and low
      reversion rate of this mutant, combined with the specificity of the defect in its
      protein-synthesizing machinery, make it an appealing tool for investigating
      regulatory mechanisms in animal cells.

PMID- 4361677
TI  - Charge transfer between amine and carbonyl.
AB  - The transfer of a whole electron in the ground state can be demonstrated by the
      interaction of p-phenylenediamine and glyoxal, which leads to the formation of
      free radicals.

PMID- 4361676
TI  - Adenosine-mediated elevation of cyclic 3':5'-adenosine monophosphate
      concentrations in cultured mouse neuroblastoma cells.
AB  - Adenosine causes an increase in the concentration of cyclic AMP in mouse
      neuroblastoma cells. The amount of increase observed in intracellular cyclic AMP
      levels due to exogenous adenosine depends greatly on the concentration of a
      specific cyclic AMP phosphodiesterase inhibitor, 4-(-3-butoxy-4-methoxybenzyl)-2
      imidazolidinone. Unstimulated concentrations of cyclic AMP were 29-40 pmol/mg of
      protein, and concentrations after addition of 0.2 mM adenosine were usually twice
      as high. The presence of 0.7 mM inhibitor along with 0.2 mM adenosine caused an
      increase in cyclic AMP levels up to 1000-2000 pmol/mg of protein. In the presence
      of 0.7 mM inhibitor, 2 muM adenosine gives a half-maximal cyclic AMP elevation.
      Theophylline blocked the elevation of cyclic AMP concentrations caused by
      exogenous adenosine. The data show that the cyclic AMP system of mouse
      neuroblastoma has the necessary receptor components to respond positively to
      exogenous adenosine. The results presented support a direct effect of adenosine,
      mediated through its control of intracellular levels, on neuronal elements of the
      nervous system.

PMID- 4361678
TI  - Heme proteins: quantum yield determined by the pulse method.
AB  - We report results of the application of the "pulse method" to the study of
      photodissociation of various ligands from several heme proteins. By use of this
      technique, which allows the determination of the quantum yield of
      photodissociation accurately and rapidly, several ligands (CO, O(2), isocyanides)
      have been investigated for sperm-whale myoglobin and trout hemoglobin I. In
      agreement with previous results, the new data lead to the conclusion that no
      simple relationship exists between the quantum yield and the affinity constant in
      the ground state. For trout hemoglobin I, the experiments were extended to
      measure the quantum yield of the CO photodissociation as a function of the
      initial degree of saturation, from fully saturated down to the initial values of
      about 1.5%. The results yield additional information to that obtained by the
      "steady-state" method, and in particular exclude the idea that the photochemical
      yield is in any way dependent on the fractional saturation of the molecule with
      carbon monoxide.

PMID- 4361679
TI  - Alteration of cell-surface proteins by viral transformation and by proteolysis.
AB  - Putative cell-surface proteins of tissue-culture cells were identified by
      lactoperoxidase-catalyzed iodination, a technique that attaches label only to
      proteins outside the cell membrane. Evidence is presented that these proteins are
      cell derived, not contaminating serum proteins. On "normal" cells, which exhibit
      density dependence of growth, one protein of high molecular weight was
      particularly readily iodinated. This protein was easily removed by mild
      proteolytic digestion, and, in virus-transformed cells, was either absent or
      unavailable for iodination. The possible relevance of these observations to the
      control of growth in cell culture is discussed.

PMID- 4361681
TI  - Pressure effect on the membrane action of a nerve-blocking spin label.
AB  - A reversible nerve-blocking spin label, 2,2,6,6-tetramethylpiperidine-1-oxyl
      (TEMPO) was used to study the nature of anesthetic-binding sites in nerve
      membranes as a function of pressure. The nerve-blocking effect of TEMPO is
      enhanced under pressure. At atmospheric pressure, TEMPO blocks nerve conduction
      by solubilizing in the apolar region of the nerve membrane. However, the nerve
      conduction-block by TEMPO at 150 atm of helium was related to the binding of
      TEMPO to a pressure-induced high-affinity polar site in the nerve membrane. The
      new TEMPO-binding site could not be detected in lipid model membranes and, thus,
      the involvement of membrane protein in the new site was inferred. Pressure may
      induce a nerve membrane conformation change in the presence of TEMPO. The
      observation that under different pressure, a single anesthetic, i.e., TEMPO, was
      capable of blocking nerve conduction by binding to two different sites within the
      nerve membrane, supports the view that there are multiple anesthetic receptor
      sites, which differ in chemical composition and location within the nerve
      membrane. These sites, when occupied by different classes of anesthetics, produce
      the general phenomenon of nerve-conduction block. The enhancement of nerve
      conduction block by pressure may be due to the increased concentration of TEMPO
      in the new site in the nerve membrane under pressure.

PMID- 4361680
TI  - Biological and biochemical evidence for an interaction between Marek's disease
      herpesvirus and avian leukosis virus in vivo.
AB  - The DNA-containing Epstein-Barr herpesvirus has been implicated in the etiology
      of Burkitt's lymphoma, a malignant tumor of children in Africa. Recently,
      however, particles possessing four biochemical characteristics of RNA tumor
      viruses have also been identified in these tumors. The fact that both types of
      viruses are found suggests that an interaction between them may be playing a role
      in the etiology of Burkitt's lymphoma. To explore this possibility with a defined
      animal model, experiments were performed with the avian Marek's disease, a
      malignant lymphoproliferative disease associated with a herpesvirus. Controlled
      contact studies demonstrated that tumorigenesis in a line of isolator-derived,
      barrier-sustained, specific pathogen-free chickens requires exposure to both the
      Marek's disease herpesvirus and an avian leukosis virus, Rous-associated virus,
      type 2. Exposure to either agent alone did not result in tumors. Molecular
      hybridization experiments to cytoplasmic RNA from similarly contact-exposed
      conventional Cornell S-line chickens provided further evidence for the occurrence
      of an interaction between Marek's disease herpesvirus and the avian leukosis
      virus.

PMID- 4361682
TI  - Plasma membranes from cultured muscle cells: isolation procedure and separation
      of putative plasma-membrane marker enzymes.
AB  - Partially purified plasma membranes were obtained from chick-embryo muscle cells
      grown in tissue culture. The purification procedure involved homogenization in
      buffered isotonic sucrose followed by differential and sucrose density gradient
      centrifugations. The activities of five plasma-membrane markers, as well as
      microsomal and mitochondrial markers, were followed throughout the purification.
      When cultures were labeled with [(125)I]alpha-bungarotoxin, which binds to the
      surface of cultured muscle cells, the distributions of bound alpha-bungarotoxin
      and Na(+),K(+)-ATPase (EC 3.6.1.3) activity were nearly identical. The activities
      of these two plasma-membrane markers were maximal in the upper two fractions of
      the sucrose density gradient and were purified 5- to 7-fold with respect to total
      particulate protein. These fractions contained 20-30% of the Na(+),K(+)-ATPase
      activity and bound alpha-bungarotoxin, 4% of the microsomal marker TPNH-dependent
      cytochrome c reductase, 0.2% of the mitochondrial marker succinate-dependent
      cytochrome c reductase, 2.7% of the cellular RNA, and 0.02% of the DNA. The
      activity of the commonly used plasma-membrane marker, 5'-nucleotidase (EC
      3.1.3.5), was low in the upper two sucrose gradient fractions and was maximal in
      a more dense fraction. The distributions of the other two plasma-membrane
      markers, leucyl beta-naphthylamidase and phosphodiesterase I, were intermediate
      between Na(+),K(+)-ATPase and 5'-nucleotidase. The distributions of all markers
      were similar in preparations from cultures containing mononucleated myogenic
      cells, multinucleated myotubes, fibroblasts, or all three cell types.
      Modification of the procedure to include homogenization in the absence of sucrose
      resulted in a 3.4-fold purification of the membranes containing 5'-nucleotidase,
      which were shifted to a lower density.

PMID- 4361683
TI  - Malignant transformation of BHK21 clone 13 cells by BK virus--a human
      papovavirus.
AB  - BK virus, a widespread human papovavirus, is shown to cause malignant
      transformation of BHK(21) clone 13 cells. The transformed cells grow as tumors
      upon inoculation in adult hamsters. The question of the possible role of this
      virus in human neoplasia is raised.

PMID- 4361684
TI  - Regulation of glucose synthesis in hormone-sensitive isolated rat hepatocytes.
AB  - A simplified procedure was developed for isolation of intact, hormone-sensitive
      liver cells in a high and reproducible yield. These cells produce glucose from
      various precursors at rates comparable to those achieved in isolated perfused
      liver. Glucagon enhanced glucose synthesis from pyruvate, dihydroxyacetone,
      fructose, or xylitol more effectively at low than at high substrate
      concentration. At high pyruvate concentrations (>2 mM), glucagon or adenosine
      3':5'-cyclic monophosphate (0.1 mM) exerts a curious inhibition of
      gluconeogenesis that can be reverted to stimulation on addition of ethanol. It is
      suggested that glucagon and cyclic AMP inhibit pyruvate dehydrogenase and thus
      limit the supply of reducing equivalents needed for glucose formation. Supporting
      evidence for hormonal control of pyruvate dehydrogenase in isolated liver cells
      is provided by the fact that glucagon decreases and insulin increases
      decarboxylation of [1-(14)C]pyruvate. Calcium salts (1.3 mM) enhance glucose
      formation from pyruvate but greatly enhance the inhibition exerted by the
      divalent cationophore, A23187. Inhibition by glucagon of glucose synthesis from
      pyruvate is additive with the effects of A23187 + Ca(++). However, with
      dihydroxyacetone as substrate, glucagon partially reverses the inhibition exerted
      by A23187 + Ca(++). The results are consistent with glucagon effecting an
      inhibition of pyruvate dehydrogenase and a stimulation of hexosediphosphatase
      activities.

PMID- 4361685
TI  - Herpes simplex and herpes genitalis viruses in etiology of some human cancers.
AB  - The results of complement fixation tests on 202 sera from people without cancer
      and from patients with cancer in 29 different areas of the body indicated that
      only those with nine varieties of advanced cancer (lip, mouth, oropharynx,
      nasopharynx, kidney, urinary bladder, prostate, cervix uteri, and vulva-all of 56
      tested) gave positive specific reactions with nonvirion antigens induced by the
      DNA herpes simplex (HSV 1) and herpes genitalis (HSV 2) viruses. None of 57
      people without cancer (including 10 with current and 18 with recurrent HSV 1 or
      HSV 2 infections), none of 81 patients with 20 other varieties of advanced cancer
      (gum, tongue, tonsil, salivary gland, accessory sinus, epiglottis, lung-bronchus,
      stomach, colon, breast, corpus uteri, ovary, testis, liver, thyroid, Wilms'
      embryonal kidney, melanoma, Hodgkin's disease, acute lymphocytic leukemia, and
      acute myelocytic leukemia), and none of four women with early malignant changes
      in the cervix uteri gave positive results. The seven patients with advanced
      cancer of the lip or oropharynx gave positive reactions with HSV 1 but not with
      HSV 2 nonvirion antigens (compatible with involvement of only HSV 1), all of the
      13 women with advanced cancer of the cervix uteri and the one woman with advanced
      cancer of the vulva gave positive reactions with both HSV 1 and HSV 2 nonvirion
      antigens (compatible with involvement of only HSV 2), while among the 35 other
      positive patients only two (one with cancer of the kidney and one with cancer of
      the bladder) reacted with HSV 1 and not at all with HSV 2 nonvirion antigens.
      Positive sera failed to react with cells harvested at different times after high
      multiplicity infection with the DNA vaccinia virus. Massive absorption of
      positive sera with trypsinized, uninfected human embryonic kidney cells failed to
      remove, or lower the titer of, the HSV 1 and HSV 2 nonvirion antibodies. All of
      these data taken together are interpreted as indicating that HSV 1 and HSV 2 play
      an etiologic role in certain human cancers, because they provide the kind of
      evidence by which virus-free experimental cancers can be proved to have been
      originally induced by such DNA viruses as polyoma, Simian Virus 40, or certain
      types of adenovirus.

PMID- 4361686
TI  - Separate intramolecular pathways for reduction and oxidation of cytochrome c in
      electron transport chain reactions.
AB  - The monoiodotyrosine 74, formyltryptophan 59, mononitrotyrosine 67, and
      carboxymethylmethionine 80 derivatives of horse cytochrome c are defective in
      their ability to accept electrons from the succinate-cytochrome c reductase
      system, while their reactions with purified cytochrome c oxidase are essentially
      those of the native protein. The 4-nitrobenzo-2-oxa-1,3-diazole derivative of
      lysine 13 of horse cytochrome c and the bis-phenylglyoxal derivative of arginine
      13 of Candida krusei cytochrome c have the opposite properties, in that they are
      readily reduced by the succinate-cytochrome c reductase (EC 1.3.99.1) system but
      are defective in their capability of transferring electrons to cytochrome c
      oxidase (EC 1.9.3.1). We conclude that electrons from mitochondrial cytochrome c
      reductase are transmitted to ferricytochrome c by a different pathway than
      electrons from ferrocytochrome c to cytochrome c oxidase. The present results are
      compatible with the concept that the mechanism of reduction involves an aromatic
      ring channel comprising residues 74, 59, 67, and 80, leading from the "left back"
      part of the protein to the heme iron. On the other hand, since residue 13 is
      immediately above the edge of the heme that is at the "front surface" of the
      molecule, we suggest that the electron leaves ferrocytochrome c to cytochrome c
      oxidase by way of the edge of pyrrole ring II or the adjacent surface-located
      sulfur of cysteinyl residue 17, which is thioether bonded to the heme. On this
      basis, the sites of electron entry and exit in cytochrome c would appear to be
      some 110 degrees of arc away from each other along the surface of the protein,
      explaining several previously observed phenomena.

PMID- 4361687
TI  - DNA of Epstein-Barr virus detected in tissue of Burkitt's lymphoma and
      nasopharyngeal carcinoma.
AB  - The association of Epstein-Barr virus (EBV) DNA with African tumors was examined
      by the method of hybridization with complementary RNA. 22 out of 23 biopsies of
      Burkitt's lymphoma and 18 out of 23 biopsies of nasopharyngeal carcinoma were
      found to contain EBV DNA. The number of EBV genome equivalents per cell ranged
      from four to 113. Five out of 24 other African tumors, two adenocarcinomas, and
      one each of melanoma, reticulum cell sarcoma, and carcinoma of the antrum, also
      contained EBV DNA.

PMID- 4361688
TI  - [Radiographic findings in neoplasms of the skull base with special reference to
      bone diagnosis].

PMID- 4361689
TI  - [Aspects of antiviral therapy in herpes infections].

PMID- 4361691
TI  - [Effect of mineral water and balneological treatment with iodated and sulfurated
      water on rickettsial, pararickettsial and adenoviral antibodies in patients with
      associated pulmonary and rheumatic chronic diseases].

PMID- 4361690
TI  - [The mechanism of viral carcinogenesis illustrated with SV40 virus].

PMID- 4361692
TI  - [On the relationship between viruses and tumor cells in vivo].

PMID- 4361693
TI  - A four-year clinical and serologic study of the use of inactivated parainfluenza
      3 virus vaccines and Pasteurella sp. bacterins in beef calves.

PMID- 4361694
TI  - [Problems and difficulties in the cytodiagnosis of bronchial carcinoma].

PMID- 4361695
TI  - [Gynecologic bilharziasis and ectopic pregnancy].

PMID- 4361696
TI  - Effect of conformational changes on the enzymatic inactivation of pig and rabbit
      skeletal muscle phosphorylase-a.

PMID- 4361697
TI  - On the nature of frequency dependence of the evoked potentials in the cat's
      auditory cortex.

PMID- 4361698
TI  - [Inhibition of corneal collagenase by cysteine and its derivatives (author's
      transl)].

PMID- 4361699
TI  - Relationship of ethanol to choline metabolism in the liver: a review.

PMID- 4361700
TI  - Plasma vitamin E and cholesterol relationship in Western Canadian Indians.

PMID- 4361701
TI  - Guanine nucleotides and their significance in biochemical processes.

PMID- 4361703
TI  - Letter: Herpesvirus type 2 infection and cervical carcinoma.

PMID- 4361702
TI  - In vitro viral studies of cells grown from human amniotic fluid samples.

PMID- 4361704
TI  - Height, weight, and lines of arrested growth in young Guatemalan children.

PMID- 4361705
TI  - Amebic liver abscess following metronidazole therapy for amebic colitis.

PMID- 4361706
TI  - Synergistic interaction of two agents in mice: Japanese B encephalitis virus and
      Trichinella spiralis.

PMID- 4361707
TI  - Needle-like cytoplasmic inclusions in the liver in prophyria cutanea tarda.

PMID- 4361708
TI  - [Current concepts on the pathogenesis of lupus nephritis].

PMID- 4361710
TI  - A proposal linking atherogenesis to the interaction of endothelial lipoprotein
      lipase with triglyceride-rich lipoproteins.

PMID- 4361711
TI  - Impaired left ventricular function in alcoholic cirrhosis with ascites.
      Ineffectiveness of ouabain.

PMID- 4361712
TI  - [Metabolic action of glucocorticoids and enzymes].

PMID- 4361709
TI  - [The reticulocyte as a cellular model of an adrenergic beta-receptor-effector
      system].

PMID- 4361713
TI  - Chromatin-bound kinase activity and phosphorylation of chromatin non-histone
      proteins during early kidney regeneration after folic acid.

PMID- 4361714
TI  - Adhesion of culture cells to their substratum.

PMID- 4361716
TI  - Intracellular antigen migration in interspecific myoblast heterokaryons.

PMID- 4361715
TI  - An unusual cytoplasmic iron-binding material that disappears from diploid cells
      placed in culture.

PMID- 4361717
TI  - Inhibition by cyclic AMP dibutyryl cyclic AMP of aggregation of embryonic quail
      liver cells in culture.

PMID- 4361718
TI  - Subfractionation and properties of rat kidney cortex microsomal fraction.

PMID- 4361719
TI  - Stimulation of 2-deoxyglucose uptake in growth-inhibited BALB-C 3T3 and revertant
      SV40-transformed 3T3 cells.

PMID- 4361720
TI  - Estrogen sensitive cell lines: establishment and characterization of new cell
      lines from estrogen-induced rat pituitary tumors.

PMID- 4361721
TI  - The relationship between concentration of prostaglandin E and rates of cell
      replication.

PMID- 4361722
TI  - Heterogeneity of the cell population of the cellular slime mold Dictyostelium
      discoideum before aggregation, and its relation to the subsequent locations of
      the cells.

PMID- 4361723
TI  - Myocardial lesions in the offspring of female rats fed a copper deficient diet.

PMID- 4361724
TI  - Effect of suramin in doses blocking trypan blue endocytosis on some enzymes in
      mouse liver.

PMID- 4361725
TI  - Stimulating effect of crystalline cholesterol on spermiogenesis and oxidative
      activity in the senile rat testicle.

PMID- 4361726
TI  - Technique of electron spin resonance investigations in the x-ray field.

PMID- 4361727
TI  - Local antibody response to experimental poliovirus infection in the central
      nervous system of rhesus monkeys.
AB  - By employing the techniques of immunofluorescence and radioimmunodiffusion using
      (32)P-labeled poliovirus as the antigen, the immunoglobulin response to
      poliovirus in serum, nasopharynx, spinal fluid, and in different segments of the
      central nervous system (CNS) was studied after intramuscular, oral, intranasal,
      and intrathalamic administration of inactivated (Salk), live attenuated (Sabin),
      or live virulent (Mahoney) type I poliovirus. Spinal fluid gammaG antibody was
      detected after immunization with Sabin or Mahoney virus and intramuscular
      administration of Salk vaccine. The response in the CNS was characterized by the
      appearance of gammaG antibody after oral or intrathalamic administration of
      Mahoney virus and rarely after intrathalamic inoculation of Sabin vaccine. The
      antibody activity in CNS was limited to the areas of poliovirus replication.
      Intrathalamic immunization with Mahoney virus resulted in local gammaG antibody
      production in the CNS in the absence of any detectable response in serum.
      Discrete foci of gammaG-containing cells were observed in those areas of CNS
      which contained poliovirus antibody. No immunoglobulin-containing cells or
      poliovirus antibody was seen in the CNS of monkeys immunized with intramuscularly
      or orally administered Sabin or Salk vaccine and in sham-immunized control
      monkeys. It is suggested that the CNS, when stimulated locally with a potent
      replicating viral antigen, may manifest a specific local antibody response, which
      is independent of the response in serum.

PMID- 4361728
TI  - California arbovirus (La Crosse) infections. II. Precipitin antibody tests for
      the diagnosis of California encephalitis.
AB  - Precipitin antibodies to California group arboviruses were studied by double agar
      gel immunodiffusion (ID) and counterimmunoelectrophoresis (CEP). Forty children
      with California encephalitis (CE), 12 patients with other forms of
      meningoencephalitis, and 120 residents of endemic CE areas were tested.
      Precipitin antibodies were detected only in the 40 patients with CE, whereas
      hemagglutination-inhibiting, neutralizing, and complement-fixing antibodies were
      also found in persons without a history of CE. Precipitin antibodies did not
      persist for more than a year, in contrast to the other three antibodies which may
      be detected for 2 or more years. Of the children with CE, 36% had precipitin
      antibodies in their acute sera by CEP and 44% by ID. Precipitin responses were
      subtype-specific, and the patients reacted most strongly with La Crosse virus.
      The results indicated that precipitin techniques would be useful for the early
      detection of CE in some patients and that the presence of precipitin antibodies
      in a patient with acute central nervous system infection is strongly suggestive
      of CE. In addition, precipitin tests can be used to distinguish the California
      subtype responsible for CE in a given area.

PMID- 4361729
TI  - Role of interferon in murine lactic dehydrogenase virus infection, in vivo and in
      vitro.
AB  - The induction of interferon (IF) by lactic dehydrogenase virus (LDV) and the
      action of exogenous IF on LDV multiplication have been studied in vivo and in
      vitro. In vivo the induction of serum IF by LDV was shown to correspond with the
      virus challenge dose. In vitro LDV-infected macrophages did not produce
      detectable IF. As to the action of IF in vivo, the prophylactic or therapeutic
      administration of IF to mice reduced the LDV serum titers only temporarily. In
      vitro, (i) the sensitivity of LDV to IF in macrophage culture was 30 times less
      than that of vesicular stomatitis virus, and 5 times less than that of Sendai
      virus, and (ii) prolonged exposure of LDV-infected macrophages to high IF
      concentrations did not cure the chronic infection, but only decreased the virus
      titer. The probable role of IF in the establishment of the early phase of a
      persistent but reduced viremia in mice is discussed.

PMID- 4361730
TI  - Continuous cyclic hormonal therapy.

PMID- 4361731
TI  - The distribution of transfer ribonucleic acid in rabbit reticulocytes. Levels of
      aminoacylation and ribosomal attachment during hemoglobin synthesis.

PMID- 4361732
TI  - The mechanism of end product inhibition of serine biosynthesis. IV. Subunit
      structure of phosphoglycerate dehydrogenase and steady state kinetic studies of
      phosphoglycerate oxidation.

PMID- 4361733
TI  - Characterization of a proposed oxytocin receptor in the uterus of the rat and
      sow.

PMID- 4361734
TI  - Rat brain tubulin and protein kinase activity.

PMID- 4361735
TI  - A new apoprotein of human plasma very low density lipoproteins.

PMID- 4361736
TI  - The involvement of serine and carboxyl groups in the activity of bovine
      pancreatic deoxyribonuclease A.

PMID- 4361737
TI  - Chicken liver phosphofructokinase. 3. Kinetics and allosteric properties.

PMID- 4361738
TI  - Regulation of mitochondrial alpha-ketoglutarate metabolism by product inhibition
      at alpha-ketoglutarate dehydrogenase.

PMID- 4361739
TI  - A mammalian endonuclease specific for apurinic sites in double-stranded
      deoxyribonucleic acid. II. Further studies on the substrate specificity.

PMID- 4361740
TI  - Membrane glycopeptides from subcellular fractions of control and virus
      transformed cells.

PMID- 4361742
TI  - The cytoplasmic estradiol receptors of bovine uterus. Their occurrence,
      interconversion, and binding properties.

PMID- 4361741
TI  - Stimulation of hydrolysis of phosphatidic acid by cholinergic agents in guinea
      pig synaptosomes.

PMID- 4361743
TI  - Synthesis of virus-capsid antigen (VCA) enhanced by ultraviolet irradiation of a
      lymphoblastoid cell line carrying Epstein-Barr virus.

PMID- 4361744
TI  - Elevated inorganic pyrophosphate concentrations in synovial fluids in
      osteoarthritis and pseudogout.

PMID- 4361745
TI  - Oxidative energy metabolism in the skeletal muscle: biochemical and
      ultrastructural evidence for adaptive changes.

PMID- 4361746
TI  - The effect of cyanate upon 2,3-diphosphoglyceric acid metabolism.

PMID- 4361747
TI  - Differential methylation of mitochondrial and nuclear DNA in cultured mouse,
      hamster and virus-transformed hamster cells. In vivo and in vitro methylation.

PMID- 4361748
TI  - Half-of-the sites reactivity in the catalytic mechanism of yeast glyceraldehyde 3
      phosphate dehydrogenase.

PMID- 4361749
TI  - Secondary structure in heterogeneous nuclear RNA: involvement of regions from
      repeated DNA sites.

PMID- 4361750
TI  - Molecular basis of negative co-operativity in rabbit muscle glyceraldehyde-3
      phosphate dehydrogenase.

PMID- 4361751
TI  - Letter: In vitro polyoma DNA synthesis: involvement of RNA in discontinuous chain
      growth.

PMID- 4361752
TI  - Accumulation of single-stranded regions in DNA and the block to replication in a
      human cell line alkylated with methyl methane sulfonate.

PMID- 4361753
TI  - Dependence of the sedimentation coefficient of denatured closed circular DNA in
      alkali on the degree of strand interwinding. The absolute sense of supercoils.

PMID- 4361754
TI  - In vitro polyoma DNA synthesis: discontinuous chain growth.

PMID- 4361755
TI  - Cystic meningiomas simulating astrocytomas. Report of three cases.

PMID- 4361756
TI  - Evidence for a vasopressor substance (renin) in human fetal kidneys.

PMID- 4361757
TI  - Prevention of malignant hypertension by the synthetic peptide SQ 20,881.

PMID- 4361758
TI  - Ultrastructure of the glomerular basement membrane in long term renal allografts
      with transplant glomerular disease.

PMID- 4361762
TI  - Persistent herpes simplex virus infection in rabbit trigeminal ganglia.

PMID- 4361764
TI  - Letter: Crystalline perinuclear inclusions in myoblasts from human dystrophic
      muscle.

PMID- 4361763
TI  - Letter: Hyperphosphatemia and hypocalcemia in neoplastic disorders.

PMID- 4361765
TI  - Analytical zonal centrifugation of synaptosomes and mitochondria from rat brain
      homogenates.

PMID- 4361766
TI  - Neuroblastoma cell differentiation: a tissue culture study using time-lapse
      cinematography.

PMID- 4361767
TI  - Description of "Minnesota Thermal Disks" and normal values of cutaneous thermal
      discrimination in man.

PMID- 4361768
TI  - Bacterial endophthalmitis after cataract extraction. II. Incidence in 36,000
      consecutive operations with special reference to preoperative topical
      antibiotics.

PMID- 4361769
TI  - Nonauditory of effects of noise.

PMID- 4361770
TI  - Acute hypertension and prolonged focal cerebral ischemia.

PMID- 4361771
TI  - Latent herpes simplex virus infection in human trigeminal ganglia.

PMID- 4361772
TI  - Reactivation of herpes simplex virus in nonpermissive cells: dependence on cell
      fusion.

PMID- 4361773
TI  - Immunoglobulin deposits in amyotrophic lateral sclerosis.

PMID- 4361774
TI  - The uptake of 36C1 into astrocytes in tissue culture by a potassium-dependent,
      saturable process: implications for epilepsy and cortical edema.

PMID- 4361775
TI  - Disorders of the immunoglobulin A system in hereditary sensory neuropathy.

PMID- 4361776
TI  - Affection of the vagus and sympathetic nerves in alcoholic polyneuropathy.

PMID- 4361777
TI  - A severe pansensory familial neuropathy.

PMID- 4361778
TI  - Peripheral nerve involvement in Tangier disease.

PMID- 4361779
TI  - Variability of neuromuscular transmission in myasthenia gravis.

PMID- 4361780
TI  - Mechanism of antibiotic-induced neuromuscular block.

PMID- 4361781
TI  - Reduced acetylcholine receptors in myasthenia gravis.

PMID- 4361782
TI  - [Characteristics of the reproductive function in women following chemotherapy for
      trophoblastic disease].

PMID- 4361783
TI  - [Cytostatics for improvement of clinical tumor surgery].

PMID- 4361784
TI  - [Cell wall of Cl. perfringens type A of different serological groups].

PMID- 4361787
TI  - Herpesvirus and Epstein-Barr virus antibodies and carcinoma of the intrinsic
      larynx.

PMID- 4361785
TI  - Leukocytes as secretory organs of inflammation.

PMID- 4361786
TI  - Hepatic cellular responses to liver cancer: abnormalities in metabolism of
      mitochondria isolated from human liver involved with carcinoma.

PMID- 4361788
TI  - [Influence of perchlorate on radioiodine elimination from the body].

PMID- 4361789
TI  - Effect of bromocarbamide on fibroblasts in vitro: fine structural changes in
      mouse fibroblasts.

PMID- 4361791
TI  - Necrotic changes of the rabbit adenohypophysis following orthostatic collapse.

PMID- 4361790
TI  - Electron microscopy of isolated rat hepatocytes before and after treatment with
      phalloidin.

PMID- 4361792
TI  - Studies on the mode of proliferation of rat liver cells in chronic thioacetamide
      intoxication.

PMID- 4361793
TI  - Ablation of the primary infero-temporal epileptogenic focus in rhesus monkeys
      with independent secondary spike discharges.

PMID- 4361794
TI  - Impaired hyperpolarising inhibition during insulin hypoglycaemia and
      fluoroacetate poisoning.

PMID- 4361795
TI  - Histochemical location of glutamic dehydrogenase and aspartate aminotransferase
      in chicken cerebellum.

PMID- 4361796
TI  - [Study of myelin figures in luteinic cells of the rat].

PMID- 4361797
TI  - [Reversible transformation of Leydig cells of swine in histiotypic culture].

PMID- 4361798
TI  - [Prolonged starvation and ultrastructure of the frog liver].

PMID- 4361800
TI  - [Paradoxical sleep and environment].

PMID- 4361799
TI  - [Effect of low-dose angiotensin II on urinary function in waking adrenalectomized
      dogs].

PMID- 4361801
TI  - [Immunofluorescent and electron microscopy of 3 lymphoblastoid lines carrying eb
      type Herpesvirus].

PMID- 4361802
TI  - Comparative studies on angiotensins. 3. Structure of fowl angiotensin and its
      identification by DNS-method.

PMID- 4361803
TI  - The urinary excretion of 1-methylimidazole-4-acetic acid, a histamine metabolite,
      by healthy and asthmatic children.

PMID- 4361804
TI  - Altered bile acid metabolism during treatment with phenobarbitone.

PMID- 4361805
TI  - Triglyceride storage disease: a group of inborn errors of triglyceride
      metabolism.

PMID- 4361806
TI  - Measurable effect (5.0--0.005 pg-ml) of ACTH acting on sections of adrenal
      cortex.

PMID- 4361807
TI  - Left ventricular function in chronic obstructive pulmonary disease with and
      without cardiac failure.

PMID- 4361808
TI  - Carbohydrate metabolism in patients with primary hepatocellular carcinoma.

PMID- 4361809
TI  - The relationship of steroid excretions to signs of sexual maturation phenomena in
      normal male adolescents.

PMID- 4361811
TI  - Propagation in vitro of functional rat adrenal cortical cells: modifications of
      the differentiated state by culture conditions.

PMID- 4361810
TI  - I-cell disease (mucolipidosis type II). Serum hydrolases in obligate
      heterozygotes.

PMID- 4361812
TI  - Effect of nonspecific factors on focus formation by Rous sarcoma virus. II.
      Polyanions, divalent cations, temperature, and tryptose phosphate broth.

PMID- 4361813
TI  - Non-cytopathic, non-productive infection by herpes simplex viruses types 1 and 2.

PMID- 4361814
TI  - Transformation of baboon cells with feline sarcoma virus.

PMID- 4361816
TI  - Effect of sequential inoculations of Sendai virus and Pasteurella pneumotropica
      in mice.

PMID- 4361815
TI  - Silica urolithiasis in laboratory dogs fed semisynthetic diets.

PMID- 4361817
TI  - Binding of 125I-human growth hormone to specific receptors in human cultured
      lymphocytes. Characterization of the interaction and a sensitive radioreceptor
      assay.

PMID- 4361818
TI  - Spin-labeled sulfonyl fluorides as active site probes of protease structure. I.
      Comparison of the active site environments in alpha-chymotrypsin and trypsin.

PMID- 4361819
TI  - Spin-labeled sulfonyl fluorides as active site probes of protease structure. II.
      Spin label syntheses and enzyme inhibition.

PMID- 4361821
TI  - Kinetic properties of allosteric adenosine monophosphate nucleosidase from
      Azotobacter vinelandii.

PMID- 4361820
TI  - Enzymatic synthesis of phosphoribosylamine in human cells.

PMID- 4361822
TI  - On the question of the existence of a guanosine triphosphate-specific protein
      kinase activated by adenosine 3':5'-monophosphate-dependent protein kinase.

PMID- 4361823
TI  - Kinetic studies on the reaction between apocytochrome c peroxidase and
      protoporphyrin IX.

PMID- 4361824
TI  - The effect of isoproterenol upon the activity and intracellular distribution of
      pyrimidine nucleoside kinases in the mouse parotid gland.

PMID- 4361825
TI  - Binding of bacitracin to cells and protoplasts of Micrococcus lysodeikticus.

PMID- 4361826
TI  - The structures of oligosaccharides accumulating in the liver of G-M1
      gangliosidosis, type I.

PMID- 4361827
TI  - Action of magnesium ion on diphosphopyridine nucleotide-linked isocitrate
      dehydrogenase from bovine heart. Characterization of the forms of the substrate
      and the modifier of the reaction.

PMID- 4361828
TI  - The molecular mechanism of the in vitro 4 S to 5 S transformation of the uterine
      estrogen receptor.

PMID- 4361829
TI  - Adenylate kinase in human tissue. I. Organ specificity of adenylate kinase
      isoenzymes.

PMID- 4361830
TI  - Structure of the carbohydrate units of IgE immunoglobulin. I. Over-all
      composition, glycopeptide isolation, and structure of the high mannose
      oligosaccharide unit.

PMID- 4361831
TI  - Structure of the carbohydrate units of IgE immunoglobulin. II. Sequence of the
      sialic acid-containing glycopeptides.

PMID- 4361832
TI  - Inhibition by dithiothreitol of the utilization of glutamine by carbamyl
      phosphate synthetase. Evidence for formation of hydrogen peroxide.

PMID- 4361834
TI  - The Trp-59 fluorescence of ferricytochrome c as a sensitive measure of the over
      all protein conformation.

PMID- 4361833
TI  - Electron paramagnetic resonance-detectable electron acceptors in beef heart
      mitochondria. Ubihydroquinone-cytochrome c reductase segment of the electron
      transfer system and complex mitochondrial fragments.

PMID- 4361835
TI  - Bactericidal effect of antibiotics on Haemophilus influenzae.

PMID- 4361836
TI  - Phosphatase activity of some Mycoplasma species.

PMID- 4361838
TI  - Herpes simplex infection of HEp-2 and L-929 cells. 2. The kinetics of virus
      multiplication and cell lysis, and the measurement of interferon production.

PMID- 4361837
TI  - The effect of chloroform, phenols, alcohols and cyanogen iodide on the swelling
      of Pseudomonas aeruginosa in various salts.

PMID- 4361839
TI  - Hospital treatment of alcoholism. A new therapeutic concept.

PMID- 4361840
TI  - The biochemistry of alcohol.

PMID- 4361842
TI  - Alteration of ethanol-induced CNS depression: ineffectiveness of drugs that
      modify cholinergic transmission.

PMID- 4361841
TI  - Application of antimony trichloride reagent in biochemical and chemotaxonomic
      studies relating to diosgenin and yamogenin in plants.

PMID- 4361843
TI  - [Tuberculosis as lysosomal infection (author's transl)].

PMID- 4361845
TI  - Kinetics and the free-radical mechanisms of tumor growth.

PMID- 4361844
TI  - Coordinating mental health systems: a national and international perspective.

PMID- 4361846
TI  - Free radical induced in rat liver by a chemical carcinogen, N-methyl-N'-nitro-N
      nitrosoguanidine.

PMID- 4361847
TI  - Nuclear magnetic resonance as a new tool in cancer research: human tumors by NMR.

PMID- 4361848
TI  - ESR signals during x-irradiation of tissue: their characteristics and
      relationship to the cancerous state.

PMID- 4361849
TI  - Experiences with ESR as a tool for surveying narcotic addiction.

PMID- 4361850
TI  - The effect of ambient temperature on spin-label immunoassay for morphine.

PMID- 4361851
TI  - Paramagnetic species and radical products in cat spinal cord.

PMID- 4361852
TI  - Structural studies of transition state analog complexes of creatine kinase.

PMID- 4361853
TI  - The use of spin labels for measuring distances in biological systems.

PMID- 4361854
TI  - Ligand-enzyme interactions and enzyme regulation.

PMID- 4361855
TI  - Magnetic resonance studies of human hemoglobins and their implications to the
      structure-function relationships in human normal and abnormal hemoglobins.

PMID- 4361856
TI  - NMR relaxation studies of the unfolding and refolding of staphylococcal nuclease
      at low pH.

PMID- 4361857
TI  - Cytochrome c-nucleotide complexes and the role of unpaired electrons in coupling
      processes.

PMID- 4361859
TI  - Ionic free radicals induced by ionizing radiation in oriented DNA.

PMID- 4361858
TI  - EPR and other studies of the anion-binding sites of transferrin.

PMID- 4361860
TI  - Effects of metal ions on radical formation in gamma-irradiated DNA in the solid
      state.

PMID- 4361861
TI  - Structure and formation of free radicals in irradiated single crystals of nucleic
      acid constituents.

PMID- 4361862
TI  - Radiation-induced radicals in thymine and its derivatives in low temperature
      glasses.

PMID- 4361863
TI  - ESR and ENDOR studies of irradiated nucleic acid constituents.

PMID- 4361864
TI  - Long-lived radiation-induced free radicals in anoxic wet DNA as studied by
      electron spin resonance spectroscopy.

PMID- 4361865
TI  - Equality of the rates of lateral diffusion of phosphatidylethanolamine and
      phosphatidylcholine spin labels in rabbit sarcoplasmic reticulum.

PMID- 4361866
TI  - The noncovalent coupling of rhodopsin and phosphatidylcholines.

PMID- 4361867
TI  - Electron spin resonance studies with the volatile anesthetics on phospholipid
      model membranes.

PMID- 4361869
TI  - Boundary lipid and fluid bilayer regions in cytochrome oxidase model membranes.

PMID- 4361868
TI  - The measurement of zero field splitting and the determination of ligand
      composition in mononuclear nonheme iron proteins.

PMID- 4361870
TI  - Triphosphate spin-label studies of allosteric interactions in hemoglobin.

PMID- 4361872
TI  - Molecular architecture of bilayer membranes.

PMID- 4361871
TI  - The use of spin labels in the study of muscle proteins.

PMID- 4361874
TI  - ESR studies of radiation damage in nucleic acids, bases, nucleosides and
      nucleotides.

PMID- 4361873
TI  - Carbon-13 NMR studies of peptide hormones and their components.

PMID- 4361876
TI  - Electron spin resonance in silkworm eggs.

PMID- 4361875
TI  - Spin-probe analysis of membrane perturbations produced by chemical and physical
      agents.

PMID- 4361877
TI  - New EPR methods for the study of very slow motion: application to spin-labeled
      hemoglobin.

PMID- 4361878
TI  - Heme-spin-label studies on human hemoglobin.

PMID- 4361879
TI  - Anomalous relaxation of water protons in solutions of copper-containing proteins.

PMID- 4361880
TI  - Carbon-13 Fourier transform NMR studies in 20 mm sample tubes: observation of
      individual carbon sites in proteins.

PMID- 4361881
TI  - ESR and NMR studies with deuterated flavodoxin.

PMID- 4361882
TI  - EPR studies of iron-sulphur proteins of plant mitochondria.

PMID- 4361883
TI  - Identification of primary photosynthetic processes.

PMID- 4361884
TI  - The role of plastocyanin in the photosynthetic electron transport chain as
      studied by EPR spectroscopy.

PMID- 4361885
TI  - Primary processes in chloroplast photosynthesis: EPR studies of bound ferredoxin
      and P700.

PMID- 4361886
TI  - Electron nuclear double resonance (ENDOR) investigation on myoglobin and
      hemoglobin.

PMID- 4361887
TI  - A fast kinetic component of ESR signal II in photosynthesis.

PMID- 4361888
TI  - Congenital adrenal hyperplasia.

PMID- 4361889
TI  - Growth and skeletal maturation in congenital adrenal hyperplasia. Review of 20
      cases.

PMID- 4361890
TI  - Isolated growth hormone deficiency. Two families with autosomal dominant
      inheritance.

PMID- 4361891
TI  - Proceedings: Uses of a routine postmortem radiography.

PMID- 4361892
TI  - Diagnosis and clinical significance of parainfluenza virus infections in
      children.

PMID- 4361893
TI  - Multiple forms of protein kinase in liver cell. I. Cytosol.

PMID- 4361894
TI  - Conformational analysis of a cyclic nucleotide: 3'-5'-adenosine monophosphate. A
      study based on the extended Huckel theory.

PMID- 4361895
TI  - Molecular mobility of polypeptides containing proline as determined by 13C
      magnetic resonance.

PMID- 4361896
TI  - [Cells of various types activated in vitro by phytohemagglutinin. Target cell
      lysis].

PMID- 4361897
TI  - [Action of digitonin, lubrol and tween-80 on cytochrome oxidase activity of
      mitochondrial preparations].

PMID- 4361898
TI  - Leiomyoma. An unusual tumour of the orbit.

PMID- 4361899
TI  - Diseases of the skin. Treatment of scalp disorders.

PMID- 4361900
TI  - Diseases of the skin. Present and future trends in approaches to skin disease.

PMID- 4361901
TI  - Protein-binding assay for plasma testosterone, after purification by column
      partition chromatography.

PMID- 4361902
TI  - Advantages and disadvantages of nephelometric measurement of serum lipids.

PMID- 4361903
TI  - Directional effects of cyclic AMP on platelets.

PMID- 4361904
TI  - [Hypercalcaemic crisis as primary manifestation of acute leukaemia in an adult
      (author's transl)].

PMID- 4361905
TI  - The effect of fetal pituitary ACTH and maternal corticosteroid on the development
      of fetal rat adrenal cortex.

PMID- 4361906
TI  - Metabolism of mammalian sympathetic ganglia.

PMID- 4361907
TI  - Role of cyclic AMP in synaptic transmission in the mammalian peripheral nervous
      system.

PMID- 4361908
TI  - Physiological significance of protein degradation in animal and bacterial cells.

PMID- 4361909
TI  - [Unusual breast tumors in the x-ray picture].

PMID- 4361910
TI  - [Therapy of sleep disorders. Polygraphic registration of the sleep-profile in
      patients with sleep disorders after administration of Clindorm].

PMID- 4361911
TI  - Nineteen paracentric chromosomal inversions in mice.
AB  - Using mutagens on sperm and spermatids we have produced nineteen chromosomal
      inversions in mice. The levels of radiation and chemical mutagen we used induced
      inversions in about one per cent of the animals screened. Nine inversions have
      been transmitted through successive generations, and the particular frequency of
      first meiotic anaphase bridges manifested by each inversion remained constant.
      The cytological properties of first meiotic anaphases varied considerably among
      the inversions. Chromosomal locations of five inversions are known. Four of the
      five are fully viable in homozygous condition.

PMID- 4361912
TI  - Ribosomal RNA cistron multiplicity and nucleolar organizers in hexaploid wheat.
AB  - The ribosomal DNA (DNA complementary to ribosomal RNA) content of twelve
      different wheat genotypes has been studied. Some of these genotypes are
      aneuploids with deletions or additions of chromosomes bearing nucleolar
      organisers. The rDNA contents of these genotypes provide several examples of a
      clear departure from a correlation between the number of rRNA cistrons and the
      number of nucleolar organisers. Thus the number of rRNA cistrons per nucleolar
      organiser is not constant in wheat. Wheat DNA was found to have a mean buoyant
      density of approximately 1.702 g/cc for all genotypes studied and rRNA hybridized
      selectively to DNA of buoyant density approximately 1.710 g/cc. The thermal
      stabilities of all the rRNA/DNA hybrids were essentially identical.

PMID- 4361913
TI  - Translocations, the predominant cause of total sterility in sons of mice treated
      with mutagens.
AB  - Histological and cytological analyses of the testes were carried out in 42
      sterile sons of males treated in the spermatozoal or spermatid stage with 250
      mg/kg ethyl methanesulfonate (EMS) alone or after prefeeding with butylated
      hydroxytoluene (BHT); or treated with 200 R X-rays. Of the 42 sterile males, 17
      had some mature spermatids, nine were blocked at diakinesis, 15 were blocked in
      pachytene, and one lacked spermatogenic cells altogether, having Sertoli cells
      only. Mitotic (spermatogonial) metaphases could therefore be analyzed in 41 of
      the males and meiotic configurations in 26.-(1) None of the males showed
      abnormalities in chromosome number, such as monosomy, trisomy, or mosaicism for
      either of these conditions. Certain classes of chromosome abnormalities that have
      been found associated with male sterility in other investigations, namely
      trisomies, XXY's, and X-autosome translocations, are not expected from treatment
      of 19A + Y cells when F(1) males are studied. (2) A very high percentage of the
      sterile males carried translocations. Direct meiotic evidence for this was found
      in 22 of the animals. In addition, 11 of the 16 that were blocked (or virtually
      blocked) in pachytene, and thus could be analyzed in mitosis only, consistently
      showed one abnormally short chromosome (or, one short plus one long), which
      presumably had resulted from unequal exchange (or sizable deficiency). Of the
      meiotically detected translocation males, 1 carried a T(A;Y), 17 had single
      autosomal translocations, and 4 had multiple autosomal rearrangements involving
      three, four, four, and six breaks, respectively. In addition, three males showed
      failure of X-Y pairing. (3) Translocations that cause sterility, rather than
      partial sterility, in males appear to be those in which at least one of the
      breaks occurs close to one end of a chromosome. The mitotic and meiotic evidences
      for this were found to be correlated. (4) It is proposed that many cases of
      induced F(1) male sterility may be the result of position effects produced when
      paracentromeric regions are translocated to euchromatic regions of certain other
      chromosomes. Since many translocations that produce partial sterility in the
      female cause complete sterility in the male, the male must be assumed to be more
      susceptible to disturbances of fertility by the postulated mechanism. (5) There
      is evidence that EMS, especially in the lower dose range, more often breaks
      chromosomes near one of their ends than does X-irradiation.

PMID- 4361914
TI  - Studies on the mechanisms of invasion in cancer. 3. Purification of a neutral
      protease of rat ascites hepatoma cell associated with production of chemotactic
      factor for cancer cells.

PMID- 4361915
TI  - Immunogenicity of embryonic antigens associated with chemically induced rat
      tumours.

PMID- 4361916
TI  - Potentiation of RSV rescue from RSV-transformed "poorly" virogenic cell lines by
      5-bromodeoxyuridine treatment before fusion with chick embryo fibroblasts.

PMID- 4361917
TI  - Further studies on the ability of regressor sera to block cell-mediated
      destruction of Rous sarcomas.

PMID- 4361918
TI  - Antigenic relatedness of simian C-type viruses.

PMID- 4361919
TI  - Sensitivity to guinea-pig serum of hamster cells transformed in vitro by two
      strains of the Rous sarcoma virus.

PMID- 4361920
TI  - Non-specific serum inhibitors of activity of haemagglutinins of rabies and
      vesicular stomatitis viruses.

PMID- 4361921
TI  - The effect of canavanine on herpes simplex virus replication.

PMID- 4361922
TI  - Interfering particles from a culture persistently infected with Parana virus.

PMID- 4361923
TI  - Lipid and protein organization in vesicular stomatitis and Sindbis viruses.

PMID- 4361924
TI  - Scintiscanning of pulmonary diseases with 67Ga-citrate.

PMID- 4361925
TI  - Imaging functional nodules of the adrenal glands with 131-I-19-iodocholesterol.

PMID- 4361927
TI  - 99mTc-pyrophosphate for bone imaging.

PMID- 4361926
TI  - The toxicity of Sn-pyrophosphate: clinical manifestations prior to acute LD50.

PMID- 4361928
TI  - Sella turcica salivary transplants in hypophysectomized animals.

PMID- 4361930
TI  - Supercoiled DNA: hydrodynamic model.

PMID- 4361929
TI  - Effect of exogenous and endogenous glucocorticosteroids on the in vitro
      stimulation of lymphocytes from sedated and awake-restrained healthy baboons.

PMID- 4361931
TI  - Cholesterol and cell membrane function: a hypothesis concerning etiology of
      atherosclerosis.

PMID- 4361932
TI  - Letter: On the inclusion of spontaneous emission in a neuronic equation of state.

PMID- 4361933
TI  - Rickets, American style.

PMID- 4361934
TI  - An administrative record system for ambulatory facilities.

PMID- 4361935
TI  - Herpes simplex infection of HEp-2 and L-929 cells. 4. The effect of lysosomal
      inhibitors.

PMID- 4361936
TI  - Control of cell division by very lysine rich histone (F1) phosphorylation.

PMID- 4361938
TI  - [Recent topics in neurobiology--with special references to neuronal cell
      differentiation and neurospecificity (author's transl)].

PMID- 4361937
TI  - Pressor effect of angiotensin II in sodium replete and deplete rats.

PMID- 4361939
TI  - The presence of radioimmunoassay renin levels in anephric man.

PMID- 4361940
TI  - Primary hyperparathyroidism and peptic ulcer disease.

PMID- 4361941
TI  - Control of and by pH.

PMID- 4361942
TI  - [Clinical x-ray comparisons in glomic neoplasms of the middle ear and base of the
      skull].

PMID- 4361943
TI  - The action of heat, chemicals and disinfectants on swine vesicular disease virus.

PMID- 4361944
TI  - [Intestinal form of cytomegalia in young children].

PMID- 4361945
TI  - [Pneumocystic pneumonia combined with localized cytomegalia in a nursing infant].

PMID- 4361946
TI  - [Review of the most common injuries of the arm nerves].

PMID- 4361947
TI  - Axon retraction following guanethidine treatment. Studies of sympathetic neurons
      in vivo.

PMID- 4361948
TI  - Electron microscopic study of rat pituitary primordium in organ culture.

PMID- 4361949
TI  - Fine structural observations of the pecten oculi capillaries of the chicken.
      Freeze-etching, scanning and transmission electron microscopic investigations.

PMID- 4361950
TI  - Sizes of granular vesicles in the rat median eminence, with special reference to
      the zona granulosa.

PMID- 4361951
TI  - Further observations on a cytoplasmic structure in the hamster oocyte.

PMID- 4361952
TI  - Absorption of protein macromolecules by the enterocytes of the carp (Cyprinus
      carpio L.). Ultrastructural and cytochemical study.

PMID- 4361954
TI  - [Ocular hypertension following local prostaglandin and changes of enzymatic
      activity in trabecular meshwork and ciliary epithelium (author's transl)].

PMID- 4361953
TI  - The structure of the salivary gland of the moth (Manduca sexta).

PMID- 4361955
TI  - [Chronic optico-neuropathy due to environmental exposure of organophosphate
      pesticides (Saku disease)--clinical and experimental study (author's transl)].

PMID- 4361956
TI  - The proteins of plasma lipoproteins: properties and significance.

PMID- 4361957
TI  - Peripheral neuropathy presenting with respiratory insufficiency as the primary
      complaint. Problem of recognizing alveolar hypoventilation due to neuromuscular
      disorders.

PMID- 4361958
TI  - Adult meningoencephalitis caused by herpesvirus hominis type 2.

PMID- 4361959
TI  - Fatal disseminated herpesvirus hominis type 2 infection in an adult with
      associated thymic dysplasia.

PMID- 4361960
TI  - Chromosomal analysis in malignant ovarian tumors.

PMID- 4361961
TI  - The synthesis of matrix components by chondrocytes in vitro in the presence of 5
      bromodeoxyuridine.

PMID- 4361964
TI  - Tentative method of analysis for cadmium content of atmospheric particulate
      matter by atomic absorption spectroscopy.

PMID- 4361963
TI  - Type II hyperlipoproteinaemia.

PMID- 4361962
TI  - Lipoprotein deficiency disorders.

PMID- 4361965
TI  - Tentative method of analysis for iron content of atmospheric particulate matter
      by atomic absorption spectroscopy.

PMID- 4361967
TI  - Tentative method of analysis for manganese content of atmospheric particulate
      matter by atomic absorption spectroscopy.

PMID- 4361966
TI  - Tentative method of analysis for lead content of atmospheric particulate matter
      by atomic absorption spectroscopy.

PMID- 4361968
TI  - Tentative method of analysis for zinc content of atmospheric particulate matter
      by atomic absorption spectroscopy.

PMID- 4361969
TI  - Fixation of manganese on quartz, limestone, dolomite and marine sediment samples.

PMID- 4361970
TI  - Lung cancer among uranium miners in the United States.

PMID- 4361972
TI  - A simplified radioimmunoassay of plasma aldosterone.

PMID- 4361971
TI  - An evaluation of the 20 minute perchlorate discharge test.

PMID- 4361973
TI  - Effect of various ACTH preparations and of metyrapone on the secretion of growth
      hormone in normal subjects and in hypopituitary patients.

PMID- 4361974
TI  - The nocturnal rise of human prolactin is dependent on sleep.

PMID- 4361975
TI  - The urinary excretion of adenosine 3',5'-monophosphate in children and
      adolescents.

PMID- 4361976
TI  - Detection of specific surface antigens on cells transformed by cytomegalovirus
      with the techniques of mixed hemagglutination and 125I-labeled antiglobulin.

PMID- 4361977
TI  - Immunity to murine sarcoma virus-inducted tumors. I. Specific T lymphocytes
      active in macrophage migration inhibition and lymphocyte transformation.

PMID- 4361978
TI  - Immunity to murine sarcoma virus-inducted tumors. II. Suppression of T cell
      mediated immunity by cells from progressor animals.

PMID- 4361979
TI  - Phagocytosis: a defense mechanism against infection with Trypanosoma cruzi.

PMID- 4361980
TI  - Periodate-induced lymphocyte transformation. IV. Mitogenic effect of NaIO4
      treated lymphocytes upon autologous lymphocytes.

PMID- 4361982
TI  - A comparative study of the ultrastructure of the sebaceous glands of man and
      other primates.

PMID- 4361981
TI  - Reversal of tumor-mediated suppression of immune reactivity by in vitro
      incubation of spleen cells.

PMID- 4361983
TI  - Hormonal control and methods of measuring sebaceous gland activity.

PMID- 4361985
TI  - Endocrinologic control of the development and activity of the human sebaceous
      gland.

PMID- 4361984
TI  - The control and measurement of sebum secretion.

PMID- 4361986
TI  - Receptor proteins for androgen in hamster sebaceous glands.

PMID- 4361987
TI  - Inhibition of dihydrotestosterone formation: an effective means of blocking
      androgen action in hamster sebaceous gland.

PMID- 4361988
TI  - Ultrastructural observations in acne vulgaris: the normal sebaceous follicle and
      acne lesions.

PMID- 4361989
TI  - Proceedings: Reinnervation of skeletal muscle in the mouse.

PMID- 4361990
TI  - Cancer of the lung in young men.

PMID- 4361991
TI  - Methionine transfer RNAs associated with avian oncornavirus 70S RNA.

PMID- 4361992
TI  - Sensitivity to amphotericin B of in vitro established cell lines.

PMID- 4361993
TI  - Dual action of praseodymium (Pr3+) on transmitter release at the frog
      neuromuscular synapse.

PMID- 4361994
TI  - Interaction of mercurials with salmon serum lipoproteins.

PMID- 4361995
TI  - Morphine-like drugs inhibit the stimulation of E prostaglandins of cyclic AMP
      formation by rat brain homogenate.

PMID- 4361997
TI  - Light-regulated guanosine 3',5'-monophosphate phosphodiesterase of bovine retina.

PMID- 4361996
TI  - Inhibitor of vesicular stomatitis virus transcriptase in purified virions.

PMID- 4361998
TI  - Similarity in the sequence of Escherichia coli dihydrofolate reductase with other
      pyridine nucleotide-requiring enzymes.

PMID- 4362000
TI  - Augmentation of cytotoxic drug action by antibodies directed at cell surface.

PMID- 4361999
TI  - Growth hormone releasing factor of microbial origin.

PMID- 4362001
TI  - Studies on the anterior pituitary hormones of the kangaroo.

PMID- 4362002
TI  - Quantitative aspects of interferon-induced plaque reduction: effects of cell age
      and dose of challenge virus.

PMID- 4362004
TI  - Oral induction of interferon by a low-molecular-weight compound.

PMID- 4362003
TI  - Antibodies to viruses of human origin in monkeys from Uganda.

PMID- 4362005
TI  - Reciprocal relationship between the in vitro synthesis and secretion of prolactin
      and growth hormone.

PMID- 4362006
TI  - Studies on the prevalence of endogenous type C virus RD 114 in cats.

PMID- 4362008
TI  - The inhibition of virus adsorption by substances induced by DEAE-dextran and poly
      I:C.

PMID- 4362007
TI  - Comparison of the ribonucleotide with the canavanine reductase system.

PMID- 4362009
TI  - The response of glucose-6-phosphatase in human and rat fetal liver cultures to
      dibutyryl cyclic AMP.

PMID- 4362010
TI  - The conjugation of bilirubin by rat hepatoma cells in tissue culture.

PMID- 4362011
TI  - Effect of the inhibition of angiotensin I converting enzyme in endotoxin and
      hemorrhagic shock.

PMID- 4362012
TI  - Stimulation and suppression of erythropoiesis in the plethoric mouse by cyclic
      nucleotides.

PMID- 4362013
TI  - Fanconi's anaemia.

PMID- 4362014
TI  - Glioblastoma multiforme of the spinal cord.

PMID- 4362015
TI  - Dietary factors affecting the pathogenicity of Entamoeba histolytica in rats.

PMID- 4362016
TI  - In vitro activity of metronidazole on Entamoeba histolytica in axenic culture.

PMID- 4362018
TI  - Proceedings: Rhabdo-virus like particles of Entamoeba histolytica.

PMID- 4362017
TI  - Proceedings: The interaction between E. histolytica and rabbit kidney cell (RK13)
      monolayers.

PMID- 4362019
TI  - Study of Naegleria aerobia by electron microscopy.

PMID- 4362020
TI  - Properties of the polyoma virus transcription complex obtained from mouse nuclei.

PMID- 4362021
TI  - Recombination between temperature-sensitive mutants of simian virus 40.

PMID- 4362022
TI  - C-type particles produced by a permanent cell line from a leukemic pig. I. Origin
      and properties of the host cells and some evidence for the occurrence of C-type
      like particles.

PMID- 4362023
TI  - Endonucleolytic DNase in oncorna viruses: role of mycoplasma.

PMID- 4362024
TI  - A comparison of the high molecular weight RNAs of visna virus and Rous sarcoma
      virus.

PMID- 4362025
TI  - Pseudotypes of vesicular stomatitis virus determined by exogenous and endogenous
      avian RNA tumor viruses.

PMID- 4362026
TI  - Stimulation of fetal thymidine kinase in cultured human fibroblasts transformed
      by SV40 virus.

PMID- 4362027
TI  - Membrane alterations which accompany MuMTV maturation. I. Studies by freeze
      cleave techniques.

PMID- 4362028
TI  - Enhancing factor for Rous sarcoma virus: in vitro assay and action on both cells
      and virus.

PMID- 4362029
TI  - Accumulation of closed-circular polyoma DNA molecules containing host DNA during
      serial passage of the virus.

PMID- 4362030
TI  - [Proceedings: Paracusia in children with normal auditory threshold].

PMID- 4362031
TI  - Extravesical malakoplakia.

PMID- 4362032
TI  - Herpesvirus varicellae isolated from human dorsal root ganglia.

PMID- 4362033
TI  - Chemotherapy of breast cancer. Investigational treatment.

PMID- 4362034
TI  - [After care following tendon surgery].

PMID- 4362035
TI  - Agents which block the action of the renin-angiotensin system.

PMID- 4362036
TI  - Senescence and the renal vasculature in normal man.

PMID- 4362038
TI  - Evidence for different angiotensin II receptors in rat adrenal glomerulosa and
      rabbit vascular smooth muscle cells. Studies with competitive antagonists.

PMID- 4362037
TI  - Inhibition by acetylcholine of adrenergic neurotransmission in vascular smooth
      muscle.

PMID- 4362039
TI  - Effect of synthetic LH-releasing factor (LRF) on LH secretion in monolayer
      cultures of the anterior pituitary cells of cynomolgus monkeys.

PMID- 4362041
TI  - A specific progesterone receptor in the hamster uterus: physiologic properties
      and regulation during the estrous cycle.

PMID- 4362040
TI  - Stimulation of 14C-cyclic AMP accumulation by FSH and LH in testis from mature
      and immature rats.

PMID- 4362042
TI  - Hypophyseal-adrenocortical role in urinary excretion of epinephrine and
      norepinephrine in hypophysectomized and adrenalectomized rats.

PMID- 4362043
TI  - Effects of colchicine on the formation of thyroid hormone.

PMID- 4362044
TI  - Action of a nonsteroidal antiandrogen, flutamide, on the receptor binding and
      nuclear retention of 5 alpha-dihydrotestosterone in rat ventral prostate.

PMID- 4362045
TI  - Acute hormonal regulation of cyclic AMP content and glycogen phosphorylase
      activity in fetal liver in organ culture.

PMID- 4362046
TI  - Rat placental delta-5-3 beta-hydroxysteroid dehydrogenase. I. Changes in activity
      with dilution and gestational age.

PMID- 4362048
TI  - Effects of projected cortical epileptiform discharges on unit activity in the cat
      cuneate nucleus.

PMID- 4362047
TI  - General presence of glucocorticoid receptors in mammalian tissues.

PMID- 4362049
TI  - Response of somatosensory cerebral neurons to stimulation of dorsal and
      dorsolateral spinal funiculi.

PMID- 4362050
TI  - The receptive surface and axonal terminals in severely denervated neurons within
      the lumbosacral cord of the dog.

PMID- 4362051
TI  - Electrical and chemosensitive properties of normal and dystrophic chicken
      muscles.

PMID- 4362052
TI  - Ontogenesis of ponto-geniculo-occipital activity in the lateral geniculate
      nucleus of the kitten.

PMID- 4362053
TI  - The development of unit activity in the lateral geniculate nucleus of the kitten.

PMID- 4362054
TI  - Effects of projected cortical epileptiform discharges on field potentials in the
      cat cuneate nucleus.

PMID- 4362055
TI  - Adenine arabinoside effect on experimental idoxuridine-resistant herpes simplex
      infection.

PMID- 4362056
TI  - Role of Ca2+ in adrenocorticotropic hormone-stimulated lipolysis in the perfused
      fat cell system.

PMID- 4362057
TI  - Ascorbate oxidase. Inhibition, activation, and pH effects.

PMID- 4362058
TI  - Activation of succinate dehydrogenase by anions and pH.

PMID- 4362059
TI  - Lipogenesis in rat hepatocytes.

PMID- 4362060
TI  - Studies on human beta-D-N-acetylhexosaminidases. I. Purification and properties.

PMID- 4362061
TI  - Interaction of fragment A from diphtheria toxin with nicotinamide adenine
      dinucleotide.

PMID- 4362062
TI  - Glucocorticoid receptors in mouse mammary tumors. Specific binding of
      glucocorticoids in the cytoplasm.

PMID- 4362063
TI  - Studies on cobalt myoglobins and hemoglobins. 3. Electron paramagnetic resonance
      studies of reversible oxygenation of cobalt myoglobins and hemoglobins.

PMID- 4362065
TI  - Effect of insulin and lipolytic agents on rat adipocyte low Km cyclic adenosine
      3':5'-monophosphate phosphodiesterase.

PMID- 4362064
TI  - Univalent reduction of molecular oxygen by spinach chloroplasts on illumination.

PMID- 4362067
TI  - Purification and characterization of lipoprotein lipase from pig adipose tissue.

PMID- 4362066
TI  - Characterization and solubilization of gonadotropin receptor of bovine corpus
      luteum.

PMID- 4362068
TI  - Metalloflavoprotein models. The crystal structure of bis(riboflavin) bis(cupric
      perchlorate) dodecahydrate.

PMID- 4362069
TI  - Quantitative aspects of the insulin-receptor interaction in liver plasma
      membranes.

PMID- 4362070
TI  - Biochemical studies on the mode of action of cytochalasin B. Preparation of
      (3H)cytochalasin B and studies on its binding of cells.

PMID- 4362071
TI  - A kinetic study of the complementation of fragments of staphylococcal nuclease.

PMID- 4362072
TI  - Characterization of cardiac muscle collagen. Molecular heterogeneity.

PMID- 4362074
TI  - Multiple disc gel bands of mitochondrial creatine and adenylate kinases.

PMID- 4362073
TI  - Membrane-bound angiotensin-converting enzyme from rat lung.

PMID- 4362075
TI  - Phosphoinositide metabolism in rat superior cervical ganglion, vagus and phrenic
      nerve: effects of electrical stimulation and various blocking agents.

PMID- 4362077
TI  - Effect of behavioural training on brain transfer RNA methylases.

PMID- 4362076
TI  - Synaptosomal plasma membranes: acyl group composition of phosphoglycerides and
      (Na+ plus K+)-ATPase activity during fatty acid deficiency.

PMID- 4362078
TI  - Effects of levorphanol on phospholipid metabolism in the giant axon of the squid.

PMID- 4362079
TI  - Calcium metabolism in isolated brain cells and subcellular fractions.

PMID- 4362081
TI  - Melanoameloblastoma.

PMID- 4362080
TI  - Cyclic nucleotide phosphodiesterase of the bovine retina: activity, subcellular
      distribution and kinetic parameters.

PMID- 4362082
TI  - ACTH and the regulation of adrenocortical secretion.

PMID- 4362083
TI  - Editorial: The gene for the poliovirus receptor.

PMID- 4362084
TI  - Pathogenesis of experimental viral hepatitis (second of two parts).

PMID- 4362085
TI  - Possible involvement of cyclic GMP in growth control of cultured mouse cells.

PMID- 4362086
TI  - Dramatic early increase in uterine eosinophils after oestrogen administration.

PMID- 4362087
TI  - Thymine-labelled deoxyoligonucleotide involved in DNA chain growth in Bacillus
      subtilis.

PMID- 4362089
TI  - Detection by DNA polymerase I of breaks produced in rat liver chromatin in vivo
      by alklating agents.

PMID- 4362088
TI  - Protease inhibitors do not block transformed cells in the G1 phase of the cell
      cycle.

PMID- 4362090
TI  - Viroids and viral hepatitis in marmosets.

PMID- 4362091
TI  - [Fredrickson type II hyperlipoproteinemia].

PMID- 4362092
TI  - Community psychiatry at UCLA: a decade of training.

PMID- 4362093
TI  - Effects of cyclopropane on contractility and the cyclic 3',5'-adenosine
      monophosphate system in the rat aorta.

PMID- 4362094
TI  - Secretory otitis media: protein and enzyme analyses.

PMID- 4362095
TI  - [Structural characteristics of the stages of formation of interneuronal
      synapses].

PMID- 4362096
TI  - Oral medicine for the dental practitioner. 2. Infections of the oral mucosa.

PMID- 4362097
TI  - The epidermis and cyclic AMP.

PMID- 4362098
TI  - Proceedings: Giant glomangioma.

PMID- 4362099
TI  - Editorial: Unsuspected cytomegalic mononucleosis.

PMID- 4362100
TI  - Cure of insulin-dependent diabetes mellitus by removal of a glucagonoma.

PMID- 4362101
TI  - The effect of pancuronium on reflex regulation of heart rate in man.

PMID- 4362104
TI  - Pemphigus vulgaris and internal malignancy.

PMID- 4362102
TI  - Cerebral response to hypocapnia in normal and brain-injured dogs.

PMID- 4362103
TI  - Lack of thrombohemorrhagic phenomena complicating childhood solid tumors.

PMID- 4362105
TI  - Herpes esophagitis complicating Hodgkin's disease.

PMID- 4362106
TI  - A survival study of intestinal and diffuse types of gastric carcinoma.

PMID- 4362108
TI  - Differential diagnosis of breast tumors. The sensitivity graded method
      ultrasonotomography and clinical evaluation of its diagnostic accuracy.

PMID- 4362107
TI  - The treatment of malignant pleural effusions.

PMID- 4362109
TI  - Serum alpha-fetoprotein in 184 Ugandan patients with hepatocellular carcinoma.
      Clinical, laboratory, and histopathologic correlations.

PMID- 4362110
TI  - A note on differentiation and divisibility of alveolar epithelial cells.

PMID- 4362111
TI  - Scanning electronmicroscopy of virus-infected respiratory epithelium.

PMID- 4362112
TI  - Morphologic and ultrastructural changes in the lungs of animals during acute
      exposure to ozone.

PMID- 4362113
TI  - Fibrous histiocytoma of the lung (sclerosing hemangioma variant?).

PMID- 4362115
TI  - Bladder dysfunction: a sign of occult colonic carcinoma.

PMID- 4362114
TI  - Endocavitary irradiation in the curative treatment of early rectal cancers.

PMID- 4362116
TI  - Myopathies in the elderly.

PMID- 4362119
TI  - Studies on the pituitary "Fellstoffwechselhormon". V. The further purification of
      lipolytic active peptides from hog pituitary glands.

PMID- 4362117
TI  - Pro-hormones in tissues and in circulation.

PMID- 4362118
TI  - Inhibitory effects of calcitonin on lipolysis and 47 calcium accumulation in rat
      adipose tissue in vivo.

PMID- 4362120
TI  - Regulation of adenylate cyclase and cyclic-AMP dependent protein kinase
      activities in A2-cell rich guinea-pig islets of Langerhans.

PMID- 4362121
TI  - Effect of cyclic AMP on ketogenesis in liver homogenates from pancreatectomized
      hypophysectomized dogs.

PMID- 4362122
TI  - Effect of irreversible adsorbents on the dissociation of the antigen-antibody
      complexes.

PMID- 4362123
TI  - Human medullary thyroid carcinoma: control of calcitonin secretion in vivo and in
      tissue culture.

PMID- 4362125
TI  - Immunology of Ascaris suum infection. I. Production of reaginic antibodies to
      worm components in rats.

PMID- 4362124
TI  - Population genetic studies of red cell enzyme polymorphisms in four Spansih
      populations.

PMID- 4362126
TI  - Heterogeneity of antigen from callus of man.

PMID- 4362127
TI  - Artificial insemination. Induced ovulation with intravenous estrogens.

PMID- 4362128
TI  - Operative culdoscopy ad treatment for the polycystic ovary.

PMID- 4362129
TI  - Toxic action of anti-H.C.G. antibody to human trophoblast.

PMID- 4362130
TI  - Improved methodology for scanning electron microscopy of the female reproductive
      tract.

PMID- 4362131
TI  - Etiology and treatment of failed pregnancies.

PMID- 4362132
TI  - Autoantibody formation against spermatozoa caused by extravasation of spermatozoa
      into the interstitium of the epididymis of aged men.

PMID- 4362134
TI  - Occurrence of embryo mortality in rabbits isoimmunized against semen.

PMID- 4362133
TI  - Preliminary efforts to capacitate rabbit sperm in vitro.

PMID- 4362135
TI  - Ovarian receptivity to human gonadotropins in primary selective pituitary
      deficiency in gonadotropins.

PMID- 4362136
TI  - Evidence for discontinuous replication of circular mitochondrial DNA molecules
      from Novikoff rat ascites hepatoma cells.
AB  - Double-forked circular molecules of mitochondrial DNA (mtDNA) from rat tissues,
      indicated by their form and size to be replicative intermediates, are of two
      structurally distinct classes. Molecules of the first class are totally double
      stranded. Molecules of the second class are defined by one daughter segment being
      totally or partially single stranded. Length histograms of daughter segments
      measuring between 2% and 44% of the total 5-microm molecular contour were
      constructed from samples of both classes of replicating molecules derived from
      mtDNA or Novikoff rat ascites hepatoma cells. For single strand-containing
      molecules, the lengths fell into eight distinct, reproducible groups with mean
      values separated by 4.1-7.6% of the circular contour length. For totally double
      stranded molecules, the lengths fell into seven groups, corresponding to seven of
      the groups found for single strand-containing molecules. These results suggest
      that along at least 44% of the contour of mtDNA molecules there exist discrete
      points at which DNA synthesis tends to be arrested. This may indicate that there
      are pauses in normal mtDNA synthesis. However, as the DNA used in these
      experiments was isolated from mitochondrial fractions, the findings may indicate
      that continuation of synthesis beyond specific points on the nucleotide strands
      requires a factor which is not available after cell disruption.

PMID- 4362137
TI  - Ultrastructural localization of cytochrome b5 on rat liver microsomes by means of
      hybrid antibodies labeled with ferritin.

PMID- 4362138
TI  - Fusion of erythrocytes and other cells with retention of erythrocyte cytoplasm:
      nuclear activation in chicken erythrocyte-melanoma heterokaryons.

PMID- 4362139
TI  - Structural analysis of phosphatidylcholine of plant tissue.
AB  - Pure preparations of phosphatidylcholine were isolated from spinach leaf
      chloroplasts, spinach leaf microsomes, and cauliflower inflorescence. The
      isolated phosphatidylcholine was treated with snake venom phospholipase A, and
      the fatty acid distribution and composition of the fatty acid methyl esters
      prepared from the lysophosphatidylcholine and the freed fatty acid were
      determined by gas-liquid chromatography. The results showed that saturated fatty
      acids were preferentially esterified at position 1 and unsaturated fatty acids at
      position 2. The phosphatidylcholine from cauliflower was also treated with
      phospholipase C. The resulting diglycerides were fractionated on AgNO(3)
      impregnated thin-layer plates. The diglyceride fractions were transesterified and
      the fatty acid composition of each was determined by gas-liquid chromatography.
      The predominant species contained linolenic acid only (22% of the total),
      linolenic and oleic acids (19%), and linolenic and palmitic acids (37%). These
      molecular species could not be accounted for by random distribution of the fatty
      acids.

PMID- 4362140
TI  - Biosynthesis of phosphatidylcholine by enzyme preparations from spinach leaves.
AB  - The enzymic incorporation of choline-1,2-(14)C from CDP-choline-1,2-(14)C into
      phosphatidylcholine by spinach leaf preparations was characterized. The enzyme
      catalyzing the incorporation, choline phosphotransferase, had a pH optimum of
      about 8.0 and required either Mn(2+) or Mg(2+) as cofactor. The saturation
      concentration of Mn(2+) was 0.3 mm and that for Mg(2+) was 13 mm. The K(m) for
      CDP-choline was 10 micro m. The choline phosphotransferase was inhibited by
      sulfhydryl reagents. The enzyme was inactivated at 30 degrees C, but this
      inactivation could be prevented by dithiothreitol and Mn(2+). Preincubation of
      the enzyme with Mn(2+) prevented inhibition by sulfhydryl reagents. The
      incorporation of diglyceride-U-(14)C into phosphatidylcholine was also studied.
      The enzyme did not show any diglyceride specificity when exogenous diglyceride
      was added, indicating that fatty acid distribution in phosphatidylcholine of
      spinach is not controlled by choline phosphotransferase.

PMID- 4362141
TI  - Serum lipoprotein accumulation in the livers of orotic acid-fed rats.
AB  - This study provides confirmation of previous observations that showed that rats
      fed a diet containing 1% orotic acid for 7 days develop a fatty liver and that
      there is an inhibition of the secretion of low density lipoproteins without
      altering general liver protein synthesis. Accumulated fat droplets (liposomes)
      are entrapped within rough endoplasmic reticulum vesicles. In this study, these
      vesicles have been shown to accumulate the apolipoproteins of low and very low
      density lipoproteins. Inhibition of lipoprotein secretion was demonstrated by
      perfusion of livers from orotic acid-fed rats with a serum-free medium. Liposomes
      were isolated from these rats. Partially delipidated liposomes, but not similarly
      treated microsomes or cell sap, were found to form a precipitation line when
      reacted against anti-low density lipoprotein antiserum. Detergent solubilization
      of the liposome followed by density gradient centrifugation resulted in a peak at
      d 1.025 g/ml containing both lipid and protein. Acrylamide electrophoresis in 8 m
      urea after total delipidation demonstrated liposomal bands which
      coelectrophoresed with three of four very low density lipoprotein bands; there
      was no band corresponding to the very low density lipoprotein band which travels
      furthest in acrylamide electrophoregrams. However, acrylamide electrophoresis of
      the apoproteins of serum high density lipoprotein from orotic acid-fed animals
      revealed the presence of the latter band. The results indicate that liver
      liposomes from orotic acid-fed rats apparently contain the low density apoprotein
      and probably several other very low density lipoprotein peptides.

PMID- 4362142
TI  - A new chromatographic system for vitamin D3 and its metabolites: resoluation of a
      new vitamin D3 metabolite.
AB  - A simple yet powerful new chromatographic procedure for vitamin D(3) and its
      metabolites is described. Liquid-gel partition chromatography on Sephadex LH-20
      using a solvent of various percentages of CHCl(3) in Skellysolve B (petroleum
      ether, bp 67-69 degrees C) permits excellent resolution of vitamin D(3), 25
      hydroxyvitamin D(3), and their more polar metabolites. Of special importance is
      the resolution of the metabolites of vitamin D(3) more polar than 25
      hydroxycholecalciferol. Because of this resolution, a new metabolite of vitamin
      D(3) has been demonstrated in the plasma of rats and in the intestines of chicks
      given 100 IU of vitamin D(3)-1,2-(3)H.

PMID- 4362143
TI  - Effect of dietary tomatine on cholesterol metabolism in the rat.
AB  - Tomatine is a virtually nonabsorbable saponin which has been used as an
      antifungal agent and analytically as a cholesterol precipitant. It was used in
      this study to determine whether or not it can form a complex with cholesterol in
      vivo in the rat intestine and what effects such complex formation would have on
      cholesterol metabolism. Rats that were fed tomatine as 1% of the diet had a
      decreased uptake of dietary cholesterol by the liver, an increased rate of
      hepatic and intestinal cholesterol synthesis as well as a partial offsetting of
      the dietary cholesterol-induced decrease in hepatic cholesterogenesis, and an
      apparent increase in sterol excretion without an effect on bile acid excretion.
      In vitro, tomatine did not sequester cholic acid as did cholestyramine. The
      results show that tomatine has an effect on cholesterol absorption and on other
      aspects of lipid metabolism in the rat similar to that of cholestyramine, with
      the notable exception that tomatine increased sterol excretion while
      cholestyramine increased bile acid excretion. It was suggested that tomatine
      forms a nonabsorbable complex with cholesterol in the rat intestine.

PMID- 4362144
TI  - Synthesis of plasma triglycerides in endogenous hypertriglyceridemia.
AB  - Radioisotopic kinetic studies of triglyceride fatty acid synthesis from serum
      free fatty acids have been performed in 20 studies of normal and lipemic
      subjects. The lipemic subjects were characterized as having carbohydrate
      responsive endogenous lipemia, and were classified as having either Type III or
      Type IV prebetalipoproteinemia. In the untreated state, triglyceride production
      was reduced relative to concentration of triglyceride when compared with the
      normal control population. In response to carbohydrate restriction an absolute
      reduction in triglyceride synthesis from free fatty acids was demonstrated. These
      data indicate that overproduction cannot be importantly implicated as the
      etiology of this form of endogenous lipemia. The patients thus represent a
      pathophysiological entity which is distinct from the normal physiological lipemia
      induced by carbohydrate feeding in which overproduction is reported to be the
      initiating event.

PMID- 4362145
TI  - Lipolytic response and adenyl cyclase activity of rat adipocytes as related to
      cell size.
AB  - The number of fat cells contained in the rat epididymal fat pad was found to
      increase rapidly as the rats grew to a weight of about 300 g. Additional
      increases in cell number above this weight were minimal. By contrast, cell size,
      as measured by the amount of triglyceride per cell, increased linearly until the
      rats reached about 600 g. Glycerol release per 10(6) cells in response to
      norepinephrine in vitro was observed to be independent of cell size. Basal
      release expressed in this manner showed a slight but significant positive
      correlation with increasing cell size. When the rate of lipolysis was based
      either on the amount of triglyceride in the incubation medium, as is the usual
      custom, or on the cell surface area, lipolysis was inversely related to cell
      size. In addition to these observations on lipolysis, it was also demonstrated
      that norepinephrine-activated adenyl cyclase activity expressed per 10(6) cells
      was unaffected by cell size. This leads to the suggestion that the number of
      adrenergic receptors in the fat cell is fixed and is independent of the size of
      the cell; as the cell enlarges, these receptors are merely distributed over a
      greater surface area.

PMID- 4362146
TI  - Chromatography of unusual lipids on thin layers of magnesium oxide.
AB  - The chromatographic behavior of some minor components of natural lipids was
      studied using layers of magnesium oxide and of commercial adsorbents containing
      magnesium oxide. The lipids investigated included wax esters, cholesteryl esters,
      diester waxes, and esters, ethers and ether-esters of ethanediol and glycerol.
      Pronounced differences were found in the patterns of separation of certain lipids
      on magnesium oxide as compared to silica gel and Florisil. The procedures
      described afford means for the detection of unusual lipids in natural materials,
      and their isolation.

PMID- 4362147
TI  - Resolution of intact phosphatidylinositols by argentation thin-layer
      chromatography.
AB  - An argentation thin-layer chromatographic method is described for the separation
      of intact phosphatidylinositols on the basis of the degree of unsaturation of
      their component fatty acids. The system is applicable for metabolic studies using
      radioactive precursors of phosphatidylinositol.

PMID- 4362148
TI  - Proceedings: Gluconeogenesis in fetal and neonatal lambs.

PMID- 4362149
TI  - Cytomegalovirus mononucleosis.

PMID- 4362150
TI  - [Histopathology of tumorous diseases of the colon (author's transl)].

PMID- 4362151
TI  - [Angiographic diagnosis of insulinomas (author's transl)].

PMID- 4362152
TI  - [Enzymohistochemistry of the liver in cholestasis].

PMID- 4362153
TI  - [Corticotropin and corticoids in hemorrhagic ulcerative colitis].

PMID- 4362154
TI  - Juvenile nasopharyngeal angiofibroma.

PMID- 4362155
TI  - Effect of camptothecin on simian virus 40 DNA.

PMID- 4362156
TI  - Antibody response and virus survival in cats vaccinated against feline leukaemia.

PMID- 4362157
TI  - Cyclic GMP response in vivo to cholinergic stimulation of gastric mucosa.

PMID- 4362158
TI  - Colchicine and vinblastine inhibit fibroblast aggregation.

PMID- 4362159
TI  - Effects of angiotensin II on central neurons.

PMID- 4362160
TI  - Alcohol ingestion following intracerebral angiotensin administration and water
      deprivation.

PMID- 4362161
TI  - Efferent innervation of vestibular and auditory receptors.

PMID- 4362162
TI  - Functional significance of connections of the inferior olive.

PMID- 4362163
TI  - [Are there immunological mechanisms for neurological memory?].

PMID- 4362165
TI  - Frequent occurrence of hypoplastic optic disks in patients with aniridia.

PMID- 4362164
TI  - Poly I-poly C and endotoxins share immunosuppressive properties and increase the
      toxicity of alpha-amanitin and hexobarbital.

PMID- 4362166
TI  - The team approach to rehabilitation after mastectomy.

PMID- 4362167
TI  - Letter: A serological survey of parainfluenza type 3 virus infection in pigs in
      Victoria.

PMID- 4362168
TI  - [Preparation for pinocytosis or rhopheocytosis of capital epithelium cells of the
      rabbit appendix].

PMID- 4362169
TI  - [Location of viral antigens in mouse mammary adenocarcinoma by immunoperoxidase].

PMID- 4362170
TI  - [Pinocytosis or rhopheocytosis of capital epithelium cells of the appendix in
      rabbits].

PMID- 4362171
TI  - [Comparative effects of E1,E2,A2,F1 alpha, F2 alpha prostaglandins on the
      division of the HeLa cells in culture].

PMID- 4362172
TI  - Respiratory metabolism of tissues in septal forebrain lesioned rats.

PMID- 4362173
TI  - Comparative studies on the digestive physiology of two sympatric species of
      Oxyrhachis (Germar) (Membracoidea: Oxyrhachinae) with notes on their taxonomy.

PMID- 4362175
TI  - [Orthology and pathology of the human placenta. 2. Pathology of the placenta].

PMID- 4362174
TI  - [General explanations on the histomorphology of breast diseases].

PMID- 4362176
TI  - [Herpesvirus diseases in children with acute leukosis. Treatment with cytosine
      arabinoside].

PMID- 4362177
TI  - Ovarian neoplasms in children and adolescents.

PMID- 4362178
TI  - Orchioblastoma--a report of two cases.

PMID- 4362180
TI  - Endodermal sinus tumor of ovary--a case report.

PMID- 4362179
TI  - Mixed hepatoblastoma--a case report.

PMID- 4362181
TI  - Microflora of fresh and dry-cured hams as affected by fresh ham storage.

PMID- 4362182
TI  - Dissociation of plasma and spinal fluid ACTH in Nelson syndrome.

PMID- 4362183
TI  - Bilateral aseptic necrosis of femur following a 16-day course of corticotropin.

PMID- 4362185
TI  - [Pattern of renin activity in plasma during the menstrual cycle and in
      postmenopausal women (author's transl)].

PMID- 4362186
TI  - Hepatoma--foetal Phe-tRNA also present in normal rat liver.

PMID- 4362187
TI  - Stimulation of calcitonin synthesis and release in vitro by calcium and dibutyryl
      cyclic AMP.

PMID- 4362188
TI  - Response of mouse melanoma cells to melanocyte stimulating hormone.

PMID- 4362189
TI  - Ultrastructural changes of erythrocyte membranes isolated with colloidal silica
      solution (Ludox).

PMID- 4362190
TI  - Nocturnal secretory patterns of FSH, GH, LH and TSH.

PMID- 4362191
TI  - [Studies on the positive inotropic mechanism of action of catecholamines].

PMID- 4362192
TI  - [Effect of dibutyryl-c-AMP on the contractile strength of the isolated human
      myocardial ventricle].

PMID- 4362193
TI  - [Enzyme pattern distribution in the internal and external layers of the
      hypertrophic myocardial tissue].

PMID- 4362184
TI  - [Immunoglobulin E. Biochemical, immunological properties and clinical
      significance (author's transl)].

PMID- 4362194
TI  - [Stages in the tumorous process according to pelvic visceral phlebographic data].

PMID- 4362195
TI  - [Immunofluorescence and the immunoelectron microscopy of virus-induced tumors of
      the mammry glands of CBA-Bln strain mice].

PMID- 4362196
TI  - [Use of the parotitis virus to overcome the genetic resistance of cells to Rous
      virus].

PMID- 4362197
TI  - [Isoenzymatic spectrum of the dehydrogenases in the cytoplasm and cell nuclei of
      a hepatoma and of the liver of tumor-bearing animals].

PMID- 4362198
TI  - [Effect of alkyl disulfones on the formation of the carcinogenic metabolite 2
      acetylaminofluorene].

PMID- 4362199
TI  - [Late results of treating malignant tumors of the female genitalia (based on data
      from foreign clinics)].

PMID- 4362200
TI  - Ultrastructural study of the pericardial organ-anterior ramifications complex
      neurosecretory terminals.

PMID- 4362201
TI  - Ultrastructure of the sexual segments of the kidney in male and female lizards,
      Cnemidophorus l. lemniscatus (L.).

PMID- 4362202
TI  - [Ultrastructure of Leydig and Sertoli cells in the testicular cycle of the Pekin
      duck. Biochemical and cytoenzymological correlations (author's transl)].

PMID- 4362203
TI  - Development of muscle spindles deprived of fusimotor innervation.

PMID- 4362204
TI  - Ultrastructural changes in the secretory cycle of parathyroid cells of winter
      frogs (Rana pipiens) after pituitary homoimplantation.

PMID- 4362205
TI  - Electron microscopic study of the substantia nigra and the strio-nigral
      projection in the rat.

PMID- 4362206
TI  - Effect of cycloheximide on the fine structure of corpus luteum in intact and
      hypophysectomized rats.

PMID- 4362207
TI  - Surface morphology of the subfornical organ in the rabbit's brain.

PMID- 4362208
TI  - Fine structure of capillaries in the pecten oculi of the sparrow, Passer
      domesticus.

PMID- 4362209
TI  - Changes in total histamine content of white blood cells (WBC) in allergy
      patients.

PMID- 4362210
TI  - Lysosomal enzymes in neurological and psychiatric conditions.

PMID- 4362211
TI  - Corticosteroids, circulating leukocytes, and erythrocytes in cattle: diurnal
      changes and effects of bacteriologic status, stage of lactation, and milk yield
      on response to adrenocorticotropin.

PMID- 4362212
TI  - Multiple viral infection in calves with acute bovine respiratory tract disease.

PMID- 4362213
TI  - Hypolipoidemia and hypergammaglobulinemia associated with experimentally induced
      anaplasmosis in calves.

PMID- 4362214
TI  - Growth of bovine cell monolayer cultures from tissue explants.

PMID- 4362215
TI  - A gas chromatographic-mass spectrometric analysis of the esterifying alcohols of
      pumpkin seed protochlorophylls.

PMID- 4362216
TI  - A rapid and sensitive radiometric assay procedure for thiamine pyrophosphokinase
      activity using anion-exchange paper discs.

PMID- 4362217
TI  - Metal-ion distribution in metalloproteins by proton-induced x-ray emission
      analysis.

PMID- 4362218
TI  - The Epstein-Barr Virus (EBV) in Burkitt's lymphoma and nasopharyngeal carcinoma.

PMID- 4362219
TI  - Molecular basis of cell proliferation: the cell cycle.

PMID- 4362220
TI  - Laboratory aids in the diagnosis of pituitary tumors.

PMID- 4362221
TI  - Humoral control of airways.

PMID- 4362222
TI  - Induction of the humoral antibody response via the respiratory tract.

PMID- 4362224
TI  - Interaction of cytochrome c peroxidase with cytochrome c.

PMID- 4362223
TI  - Synthesis of polyadenosine diphosphate ribose by isolated nuclei of swine aortic
      tissue.

PMID- 4362225
TI  - Some properties of a cytochrome c-mixed mitochondrial phospholipid complex.

PMID- 4362226
TI  - Biosynthesis of head-to-head terpenes. Carbonium ion rearrangements which lead to
      head-to-head terpenes.

PMID- 4362227
TI  - Base-sequence relationships between avian ribonucleic acid endogenous and sarcoma
      viruses assayed by competitive ribonucleic acid-deoxyribonucleic acid
      hybridization.

PMID- 4362229
TI  - Synthesis of peptides with the solid phase method. II. Octapeptide analogues of
      angiotensin II.

PMID- 4362228
TI  - Synthesis of peptides by the solid phase method. I. Tetradecapeptide renin
      substrate and intermediate peptides, nonapeptides, and fragments of angiotensin
      II.

PMID- 4362230
TI  - The separation and partial purification of the soluble 17 alpha- and 17 beta
      hydroxysteroid dehydrogenases of rabbit liver.

PMID- 4362231
TI  - Adenosine-3',5'-monophosphate-dependent protein kinase from bovine anterior
      pituitary gland. 3. Structural specificity of the ATP site of the catalytic
      subunit.

PMID- 4362232
TI  - Metabolism and transport of purine nucleosides by membrane preparations of
      Micrococcus sodonensis.

PMID- 4362233
TI  - [Translation of cellular and viral information RNA in extracts from cells
      infected with encephalomyocarditis viruses].

PMID- 4362234
TI  - Respiratory viral infections among thoroughbred horses in training during 1972.

PMID- 4362235
TI  - Abnormal property of human mutant hypoxanthine-guanine phosphoribosyltransferase:
      insensitivity of fibroblast enzyme to stabilization against freezing and thawing
      by 5-phosphoribosyl-1-pyrophosphate.

PMID- 4362236
TI  - [Metabolic abnormality in erthyrocytes with atypical pyruvate kinase and
      potassium deficiency].

PMID- 4362237
TI  - [Editorial: Renin, angiotensin and hypertension].

PMID- 4362238
TI  - [Leukocyte adhesion inhibition: a simple in-vitro test for the detection of tumor
      specific immunity and blocking serum factors in children with malignant
      neoplasms].

PMID- 4362240
TI  - Carcinomatous neuromyopathy. 1. Electrophysiological studies. An
      electrophysiological and immunological study of patients with carcinoma of the
      lung.
AB  - A high incidence of asymptomatic neuromuscular disease was found. More than half
      showed EMG evidence of a 'myopathy' and of denervation. The commonest syndrome
      was a neuromyopathy with myopathic units and spontaneous muscle activity,
      especially fasciculations and nerve fibre loss but with normal or near normal
      nerve conduction. This is thought to be the result of a neuronal or axonal
      disorder.

PMID- 4362241
TI  - Carcinomatous neuromyopathy. 2. Immunological studies. An electrophysiological
      and immunological study of patients with carcinoma of the lung.
AB  - Significant cellular sensitivity to peripheral nerve antigens was found by MIF
      assay in 36% of patients with lung cancer (P<0.005) as compared with 62% of
      patients with peripheral neuropathy without neoplasia. No sensitivity was found
      in controls or the cancer sub-group without neuromuscular abnormality. The
      significance of these findings for an immune mechanism is discussed.

PMID- 4362243
TI  - Voluntary control of arm movement in athetotic patients.
AB  - Visual tracking tests have been employed to provide a quantitative description of
      voluntary control of arm movement in a group of patients suffering from athetoid
      cerebral palsy. Voluntary control was impaired in all patients in a
      characteristic manner. Maximum velocity and acceleration of arm movement were
      reduced to about 30-50% of their values in normal subjects and the time lag of
      the response to a visual stimulus was two or three times greater than in normals.
      Tracking transmission characteristics indicated a degree of underdamping which
      was not presnet in normal or spastic patients. This underdamping could be
      responsible for a low frequency (0.3-0.6 Hz) transient oscillation in elbow-angle
      movements associated with sudden voluntary movement. The maximum frequency at
      which patients could produce a coherent tracking response was only 50% of that in
      normal subjects and the relationship between the electromyogram and muscle
      contraction indicated that the mechanical load on the biceps muscle was abnormal,
      possibly due to increased stiffness of joint movement caused by involuntary
      activity in agonist and antagonist muscles acting across the joint.

PMID- 4362242
TI  - Impulse conduction in multiple sclerosis: a theoretical basis for modification by
      temperature and pharmacological agents.
AB  - The simplest model for explaining conduction defects in multiple sclerosis (MS)
      and other demyelinating diseases assumes that the only abnormality present is
      loss of myelin. The consequences of such an assumption have been investigated by
      numerical solution of a well-known set of differential equations describing
      conduction in a model demyelinated axon. In agreement with clinical findings, we
      show that this model predicts that the temperature at which conduction block
      occurs is a steep function of the extent of demyelination, so that small
      temperature increases may block large numbers of conducting fibres. Decreasing
      calcium concentration (or increasing pH) is calculated markedly to improve the
      conduction velocity of conducting demyelinated fibres and will, in addition,
      restore conduction in blocked fibres. The effects of other pharmacological agents
      have also been computed. The presence of a demyelinating lesion in a nerve fibre
      is shown greatly to impair the ability of the fibre to conduct repetitive
      impulses, conduction failing at much lower frequencies than in normal fibres.
      These calculations provide some insight into the nature of conduction defects in
      demyelinated nerve, demonstrate that many clinical features of MS are the
      expected consequence of loss of myelin and do not require the presence of other
      defects for their explanation, and provide a useful approach to the search for a
      symptomatic therapy.

PMID- 4362244
TI  - Creutzfeldt-Jakob disease: further similarities with kuru.
AB  - A typical case of Creutzfeldt-Jakob disease is described. Two unusual
      morphological features-namely, 'kuru-like' plaques in the cerebellum and coarsely
      vacuolated neurones in the striatum-are further similarities between Creutzfeldt
      Jakob disease and kuru.

PMID- 4362245
TI  - Interstitial nephritis in rats immunized with heterologous tubular basement
      membrane.

PMID- 4362246
TI  - Vitamin B6 deficiency in uremia and its implications for the depression of immune
      responses.

PMID- 4362248
TI  - Typing of Herpesvirus simplex hominis 1 and 2 by indirect immunofluorescence.

PMID- 4362247
TI  - Antibodies to common ovine and bovine C-type virus specific antigen in serum from
      sheep with spontaneous leukosis and from inoculated animals.

PMID- 4362249
TI  - [Intermittent immunosuppressive therapy in idiopathic hemosiderosis of the lung
      (author's transl)].

PMID- 4362250
TI  - [How to advance antihypertensive therapy].

PMID- 4362255
TI  - The isolation of a reovirus-like agent associated with diarrhoea in colostrum
      deprived calves in Great Britain.

PMID- 4362256
TI  - Changes in ionic composition of allantoic fluid during adrenocorticotrophin
      infusion into fetal sheep.

PMID- 4362257
TI  - Avian adenoviruses: a study of 8 field isolates.

PMID- 4362258
TI  - The effect of infectious bronchitis (IB) virus on day-old chicks previously
      infected as 17-day-old embryos with an avian adenovirus.

PMID- 4362259
TI  - [Tumours of the trachea and their surgical treatment (author's transl)].

PMID- 4362260
TI  - [ACTH test in the acute period of a closed craniocerebral injury].

PMID- 4362261
TI  - [Relationship of the mechanism of the natural cellular resistance of the human
      embryo to Rous sarcoma virus to the conditions for the release of the viral
      genome in them].

PMID- 4362262
TI  - [Antiviral activity of 5-bromouridine in an experiment and its therapeutic
      effectiveness in herpesvirus infection of the eyes].

PMID- 4362263
TI  - [Some properties of large- and small-plaque mutants of the vesicular stomatitis
      virus detectable in cell cultures].

PMID- 4362265
TI  - [Study of the biological properties of vaccinal strains of type 3 poliomyelitis
      virus isolated from children in Sverdlovsk].

PMID- 4362264
TI  - [Accumulation of specific foot-and-mouth disease virus antibodies in the ascitic
      fluid of white rats].

PMID- 4362266
TI  - Gastrointestinal hormones.

PMID- 4362267
TI  - [Lipid studies in myocardial infarct, angina pectoris and obliterating
      arteriosclerosis].

PMID- 4362268
TI  - [The carcinogenic action of N-ethyl-N-nitrosourea (ENU) in rabbits (author's
      transl)].

PMID- 4362269
TI  - [Malignant histiocytoma of the skin (author's transl)].

PMID- 4362270
TI  - [Heterologous mixed mesodermal (Mullerian) tumors of the uterus. Contribution to
      morphology and histochemistry (author's transl)].

PMID- 4362271
TI  - [Adrenal cortical function in farm animals using cortisol and corticosterone
      determination based on the principle of competitive protein binding analysis. 1.
      Measurement methods].

PMID- 4362272
TI  - An electron microscopical study of the cerebral cortex of the calf. II. The calf
      with amprolium-induced cerebrocortical necrosis.

PMID- 4362273
TI  - Radiological appearances of hepatic tumours in Hong Kong.

PMID- 4362274
TI  - Cross-sensitivities of X-ray and UV-light of two strains of murine lymphoma
      L5178y cells in vitro.

PMID- 4362275
TI  - [Immunofluorescence and immunohistochemistry in the diagnosis of cutaneous-mucous
      bullous diseases].

PMID- 4362277
TI  - [Most common phrenicopathies].

PMID- 4362276
TI  - Clinical thermography.

PMID- 4362278
TI  - [Underlying diseases in urinary tract infections--viral serologic investigations
      (author's transl)].

PMID- 4362279
TI  - Amoebiasis and the Entamoeba histolytica.

PMID- 4362280
TI  - Obstruction of the vasa deferentia of the male rat and rabbit with silastic
      medical adhesive.

PMID- 4362281
TI  - Fertility control by continuous administration of d-Norgestrel, 0.03 mg.

PMID- 4362283
TI  - Oral contraceptives and correlation between serum copper and ceruloplasmin
      levels.

PMID- 4362282
TI  - Physiology and physiopathology of the fallopian tube.

PMID- 4362284
TI  - Effect of vasoligation of 14-day-old and 21-day-old rats on spermatogenesis.

PMID- 4362285
TI  - Tuboplasty for infertility. A review of 100 cases.

PMID- 4362286
TI  - Melatonin action on the time course of compensatory ovarian hypertrophy in the
      Swiss-Webster mouse.

PMID- 4362288
TI  - [Cushing's syndrome in childhood caused by adrenal adenoma. Differential
      diagnostic significance of hormone analyses and roentgenologic procedures].

PMID- 4362289
TI  - The family practice approach to management of illness in the academic setting.

PMID- 4362290
TI  - Two-stage phosphorylation techniques: light-to-dark and acid-to-base procedures.

PMID- 4362291
TI  - Light intensity measurement; characteristics of light sources; filters and
      monochromators.

PMID- 4362292
TI  - Enhancement.

PMID- 4362293
TI  - Clostridial rubredoxin.

PMID- 4362294
TI  - Purification of nitrogenase and crystallization of its Mo-Fe protein.

PMID- 4362295
TI  - Techniques for studying light-induced paramagnetism in photosynthetic materials
      by means of electron paramagnetic resonance spectroscopy.

PMID- 4362296
TI  - [Location and prognosis of iatrogenic nerve lesions (author's transl)].

PMID- 4362297
TI  - [Postsynaptic inhibition in the neurons in the frog primordial hippocampus].

PMID- 4362298
TI  - [Study of the neuronal connections in the dorsocaudal portion of the cat midbrain
      tegmentum using a microstimulation method].

PMID- 4362299
TI  - [Morphological and functional characteristics of the restoration of the
      retinotectal connections in the frog with a regenerating optic nerve].

PMID- 4362300
TI  - [Interaction of visceral, somatic and visual signals in single neurons of the
      external lateral geniculate bodies of the cat].

PMID- 4362301
TI  - [Transmission by certain groups of spinal interneurons of the descending activity
      evoked by prolonged stimulation of the pyramides and red nucleus].

PMID- 4362302
TI  - [Effect of passive movements on lactate and pyruvate concentration in venous
      blood of paretic limbs in paresis of central origin].

PMID- 4362303
TI  - [Use of cytochrome "C" for preventing and treating asphyxia neonatorum and intra
      uterine fetal hypoxia].

PMID- 4362306
TI  - [Hyperchylomicronemia and hyperprebetalipoproteinemia. Study of the lipoprotein
      lipase system].

PMID- 4362307
TI  - [Effect of viral and bacterial infections on the development and course of
      pneumonia].

PMID- 4362308
TI  - Non-surgical treatment of lung cancer--selection of cases for surgery.

PMID- 4362309
TI  - The treatment of carcinoma of the lung by radiotherapy.

PMID- 4362310
TI  - [Ultrasonic effect on 5-hydroxytryptamine level of blood (author's transl)].

PMID- 4362311
TI  - [Some thoughts on the importance of follow-up rehabilitation (author's transl)].

PMID- 4362312
TI  - [Alveolar cell carcinoma].

PMID- 4362313
TI  - [Relations between the radiosensitivity of a higher organism and the adenylate
      cyclase-system of its cells].

PMID- 4362314
TI  - [Dosimetry in rabbit lymph nodes following endolymphatic therapy using
      radionuclides].

PMID- 4362316
TI  - [RNA in neurons and their glial cell-satellites in the rat red nucleus during
      natural sleep, deprivation of its paradoxical phase and phenamine insomnia].

PMID- 4362315
TI  - [Ultrastructure of functionally different skeletal muscle fibers of the bog
      turtle Emys orbicularis].

PMID- 4362318
TI  - [Effect of tryptophan derivatives on monkey and human chromosomes].

PMID- 4362319
TI  - [Modeling the changes in T-system tubules of muscle fibers during influx and
      efflux of low-molecular non-electrolytes].

PMID- 4362317
TI  - [Effect of monovalent ions on the glycolysis and respiration of ascitic tumor
      cells].

PMID- 4362320
TI  - A porcine Enterovirus causing fetal death and mummification. I. Characteristics
      and identification.

PMID- 4362322
TI  - Immunological activity of foot-and-mouth disease virus purified by polyethylene
      glycol precipitation.

PMID- 4362321
TI  - A porcine Enterovirus causing fetal death and mummification. II. Experimental
      infection of pregnant sows.

PMID- 4362323
TI  - Studies of the foot-and-mouth disease virus sub-types using antigens inactivated
      by gamma radiations.

PMID- 4362324
TI  - Some characteristics of the immune response to cytomegalovirus infection.

PMID- 4362325
TI  - [Jugulography in tumors of the glomus jugulare].

PMID- 4362326
TI  - [Radioimmunological determination of human chorionic somatomammotropin hormone by
      immunoabsorbent antibodies. Application to clinical obstetrics and research in
      ectopic hormonal secretions].

PMID- 4362327
TI  - [Parotid steroid excretion in relation to plasma cortisol variations].

PMID- 4362328
TI  - [Enzyme histochemistry in human skin tumors. Epithelium-stroma interrelationships
      (author's transl)].

PMID- 4362329
TI  - [The deep supratentorial cerebral veins. Radio-anatomy. II. Tumoral pathology].

PMID- 4362330
TI  - Comparison of the turnover patterns of total and individual muscle proteins in
      normal mice and those with hereditary muscular dystrophy.
AB  - 1. The incorporation of amino acids into hindleg muscle proteins of normal and
      dystrophic mice was measured (1/2)h to 16 days after administration of the
      radioactive pulse. 2. Dystrophic animals showed a faster initial rate of
      incorporation into total and soluble proteins in the first few hours after
      injection, but the extent of incorporation relative to the size of the amino acid
      pool was similar in both. There was little difference between the overall
      degradation rates although this started later in the dystrophic proteins. An
      initial fast phase of degradation reached a plateau after 3 days whereupon the
      residual label in the protein remained constant up to 16 days after injection. 3.
      Analyses of individual radioactive proteins fractionated by polyacrylamide-gel
      electrophoresis showed that the distribution of label was similar in all the
      soluble proteins from normal and dystrophic muscle. Time-course experiments
      revealed that in dystrophic mice the two major soluble proteins of the muscle,
      creatine kinase and adenylate kinase, initially incorporated 2-3 times more label
      relative to the initial size of the precursor pool. This label was then lost
      equally rapidly and the final plateau value was much less than that in normal
      mice. This initial peak of activity was not observed in normal mice. 4. A group
      of dehydrogenases showed similar initial turnover patterns in both dystrophic and
      normal mice but the final plateau value was much higher in the former. 5. The
      results provide support for the hypothesis that there is no obvious defect in the
      protein synthetic machinery of dystrophic muscle. However, certain proteins do
      show anomalous turnover patterns relative to those in normal animals. A single
      structural gene mutation giving rise to one particularly unstable and readily
      degradable muscle protein is excluded as the cause of the dystrophy.

PMID- 4362331
TI  - The metabolism of nitrilotriacetate by a pseudomonad.
AB  - 1. An organism that grows on nitrilotriacetate as sole source of carbon and
      energy was isolated in pure culture and was identified as a pseudomonad. 2. Cell
      free extracts of the nitrilotriacetate-grown pseudomonad contain an enzyme that
      catalyses the NADH-and O(2)-dependent oxidation of nitrilotriacetate to
      iminodiacetate and glyoxalate. This enzyme is absent from extracts of glucose
      grown cells. 3. Compared with growth on glucose, growth on nitrilotriacetate
      results in increased activities of enzymes of glycine and serine metabolism,
      namely serine hydroxymethyltransferase, glycine decarboxylase, serine
      oxaloacetate aminotransferase and hydroxypyruvate reductase. 4. Cell-free
      extracts of the nitrilotriacetate-grown organism contain the enzyme glyoxalate
      carboligase and, when supplemented with NADH, Mg(2+) and thiamin pyrophosphate,
      can catalyse the anaerobic conversion of glyoxalate into glycerate. 5. These
      results are incorporated in a scheme which shows the oxidative metabolism of
      nitrilotriacetate by the successive removal of C(2) units to form 2mol of
      glyoxalate and 1mol of glycine per mol of nitrilotriacetate degraded. The
      glyoxalate and glycine are then both metabolized to glycerate by separate
      pathways, via tartronic semialdehyde and serine respectively. The role of this
      scheme in the growth of the organism on nitrilotriacetate is discussed.

PMID- 4362332
TI  - Induction of delta-aminolaevulinate synthetase under environmental-stress
      conditions.
AB  - 1. Exposure of rats to environmental-stress conditions of hypobaria, hypoxia and
      cold did not alter the activity of hepatic delta-aminolaevulinate synthetase. 2.
      Induction of the enzyme by diethoxycarbonyldihydrocollidine was inhibited when
      the rats were exposed to hypobaria before or during the treatment with the drug
      but not after the initial phase when the process of induction was initiated.
      Neither increased concentration of the drug nor the time of induction had any
      effect on the inhibition under hypobaria. 3. A period of 12-24h of pre-exposure
      to hypobaria gave the maximum inhibition, and on longer exposure the inhibitory
      effect was decreased. 4. The inhibition was not a permanent effect and could be
      substantially reversed in 12h of withdrawal to ambient pressure. 5. Inhibition of
      induction was found under hypobaria and hypoxia, but not on exposure to cold.
      This suggests a specific effect of lack of O(2) rather than a general effect of
      stress. 6. It appears possible that alteration of concentration of endogenous
      adenine nucleotides may control the process of diethoxycarbonyldihydrocollidine
      mediated induction of delta-aminolaevulinate synthetase, since treatment with
      ATP, cyclic AMP or theophylline produced inhibition similar to that under
      hypobaria and hypoxia.

PMID- 4362334
TI  - Criteria for identifying a myelin-like fraction from developing brain.
AB  - Multiple criteria must be used to relate a membrane fraction (;myelin-like') to
      myelin. These reported in this communication are electron microscopy, marker
      enzymes, sodium dodecyl sulphate-polyacrylamide-gel electrophoretic patterns and
      lipid composition.

PMID- 4362335
TI  - The effect of ethylene on (1-14C)glycerol incorporation into phospholipids of
      etiolated pea stems.
AB  - The effect of ethylene (10 p.p.m.) on the rate of incorporation of [1
      (14)C]glycerol into phospholipids of etiolated pea stems was studied. After 2-3h
      treatment with ethylene, incorporation was decreased by 50%. It remained at this
      value for as long as ethylene was supplied (8h). Handling the plants also caused
      a temporary decrease in incorporation, which we attribute to the production of
      endogenous ;wound' ethylene. The percentage decrease in incorporation was the
      same in four major phospholipid fractions, i.e. phosphatidylcholine,
      phosphatidylethanolamine, phosphatidylglycerol and phosphatidylinositol.

PMID- 4362333
TI  - Progesterone and the metabolic control of the lactose biosynthetic pathway during
      lactogenesis in the rat.
AB  - 1. Lactogenesis was initiated in pregnant rats by ovariectomy, thereby causing
      progesterone withdrawal, after which the mammary tissue was analysed for contents
      of enzymes and metabolites concerned with the biosynthesis of lactose. 2. Lactose
      synthesis increased about 126-fold with little or no accompanying change in the
      contents of most metabolic intermediates or in the adenine nucleotide energy
      charge. 3. Comparison of mass-action ratios with equilibrium constants showed
      that phosphoglucomutase (EC 2.7.5.1), UDP-glucose pyrophosphorylase (EC 2.7.7.9)
      and UDP-glucose epimerase (EC 5.1.3.2.) catalysed reactions close to equilibrium.
      Nucleoside diphosphokinase (EC 2.7.4.6.) activity was very high and probably
      equilibrates the UTP-UDP and ATP-ADP couples. Lactose synthetase and hexokinase
      (EC 2.7.1.1) appeared to catalyse rate-limiting reactions. 4. Large increases
      were seen of UDP-glucose pyrophosphorylase (5-fold), lactose synthetase A protein
      (3.8-fold) and alpha-lactalbumin (28-fold), but not of hexokinase,
      phosphoglucomutase, UDP-glucose epimerase, nucleoside diphosphokinase or glucose
      6-phosphate dehydrogenase (EC 1.1.1.49) activities. 5. It appeared that the
      increased lactose synthesis was largely accounted for by the increased lactose
      synthetase A protein activity and alpha-lactalbumin.

PMID- 4362337
TI  - The metabolism of benzene by bacteria. Purification and some properties of the
      enzyme cis-1,2-dihydroxycyclohexa-3,5-diene (nicotinamide adenine dinucleotide)
      oxidoreductase (cis-benzene glycol dehydrogenase).
AB  - 1. cis-Benzene glycol dehydrogenase was purified to a homogeneous state from a
      species of Pseudomonas grown with benzene as the major carbon source. 2. The
      enzyme was specific for the cis-isomer of its substrate and required NAD(+) as
      hydrogen acceptor. 3. Partial inactivation of the enzyme, which was observed
      during purification, could be reversed by the addition of Fe(2+) and GSH. 4. A
      molecular weight of 440000 was calculated from data obtained by sedimentation
      velocity and diffusion analysis in the ultracentrifuge. Sodium dodecyl sulphate
      polyacrylamide-gel electrophoresis indicated a subunit of molecular weight
      110000. 5. p-Chloromercuribenzoic acid and 1,10-phenanthroline were shown to
      inhibit the enzyme.

PMID- 4362336
TI  - Output of (14C)adenine nucleotides and their derivatives from cerebral tissues.
      Tetrodotoxin-resistant and calcium ion-requiring components.
AB  - 1. Neocortical tissues, exposed briefly to [(14)C]adenine and containing over 98%
      of their (14)C as adenine nucleotides, when superfused with glucose-bicarbonate
      salines released about 0.1% of their (14)C content/min to the superfusate. 2.
      Addition of unlabelled adenosine to the superfusing fluid increased the (14)C
      output three- to four-fold; half-maximal increase was given by about 40mum
      adenosine, and reasons are adduced for considering the activity of adenosine
      kinase to be a major factor in conditioning the (14)C output. Adenosine similarly
      increased the enhanced (14)C output caused by electrical excitation of the
      superfused tissue; it brought about only a small increase in tissue glycolysis.
      3. Output of (14)C from the [(14)C]adenine-labelled tissues was increased when
      Ca(2+) was omitted from the superfusing fluids, but electrical stimulation did
      not then liberate more (14)C. Nevertheless, such tissues still responded to
      electrical stimulation by increased glycolysis, and their (14)C output again
      became susceptible to increase by electrical stimulation when Ca(2+) was
      restored. 4. The six-fold increase in tissue glycolysis caused by electrical
      excitation was almost completely inhibited by tetrodotoxin at 0.1mum and above,
      but this was associated with about 50% inhibition only in the output of (14)C
      from tissues preincubated with [(14)C]adenine. The (14)C-labelled compounds of
      which output was most inhibited by tetrodotoxin were adenosine, inosine and
      hypoxanthine whereas output in a nucleotide fraction was little affected.

PMID- 4362338
TI  - The role of protein kinase activation in the control of steroidogenesis by
      adrenocorticotrophic hormone in the adrenal cortex.
AB  - A method has been developed for investigation of the effect of
      adrenocorticotrophic hormone (ACTH) on the state of activation of a cyclic AMP
      dependent protein kinase within cells of the adrenal cortex. Enzyme activity was
      measured in terms of the quantity of (32)P transferred from [gamma-(32)P]ATP to
      histone under conditions in which bound cyclic AMP did not dissociate from the
      regulatory subunit of the protein kinase ACTH (1x10(-2)i.u./ml) caused a rapid
      and complete activation of the cyclic AMP-dependent protein kinase activity
      within 2min of hormone addition to the isolated cells. In response to a range of
      ACTH concentrations a sigmoid log dose-response curve for protein kinase
      activation was obtained, with half-maximal stimulation attained at about 1x10(
      3)i.u./ml. However, some low doses of ACTH that elicited a marked (but
      submaximal) steroidogenic response failed to cause a clear stimulation of protein
      kinase activity in isolated adrenal cells. Theophylline (2mm) potentiated the
      effect of ACTH on protein kinase activity. The results implicate an important
      role for protein kinase in ACTH action on the adrenocortical cell.

PMID- 4362339
TI  - [Purification of guanosine phosphorylase of Bacillus cereus].

PMID- 4362341
TI  - [Proteinuria caused by angiotensin: blood protein clearance].

PMID- 4362340
TI  - [Demonstration of serum antibodies naturally induced by respiratory tract viruses
      in Roman children].

PMID- 4362342
TI  - Studies in the basic mineralizing system, CaO-P2O5-H2O.

PMID- 4362343
TI  - Microchemical studies of acid glycosaminoglycans from isolated chondrocytes in
      suspension.

PMID- 4362345
TI  - Synthesis of a C-nucleoside analog of the antibiotic cordycepin.

PMID- 4362344
TI  - Ultrastructure and lysosomal histochemistry of ia rat osteoclasts.

PMID- 4362346
TI  - [Demonstration of glycosyltransferases in hepatocytes of a teleost, the
      wrasse(Labrus bergylta)].

PMID- 4362347
TI  - Synthesis of 6-O-alpha-L-fucopyranosyl-D-galactose.

PMID- 4362348
TI  - Residential treatment of disturbed children: a study of service delivery.

PMID- 4362349
TI  - Partial purification of the crowding factor from Carassius auratus and Cyprinus
      carpio.

PMID- 4362350
TI  - Inhibitory effect of dibutyryl cAMP on mouse oocyte maturation in vitro.

PMID- 4362351
TI  - Substituted piperazinoquinazolones: relationship between selective inhibition of
      nicotinamide adenine dinucleotide-dependent oxidations and anticonvulsant
      activity.

PMID- 4362352
TI  - Substituted benzoxazole-benzthiazole-2-thiones: interrelationship between
      anticonvulsant activity and inhibition of nicotinamide adenine dinucleotide
      dependent oxidations and monoamine oxidase.

PMID- 4362353
TI  - Semisolid oleaginous ointment bases for ophthalmic use.

PMID- 4362354
TI  - [Thyrotoxic crisis: symptomatology and therapy. 2].

PMID- 4362355
TI  - [A case of multiple intestinal and urinary tract carcinoma].

PMID- 4362356
TI  - [Acute liver disease with fatal outcome caused by cytomegalovirus infection
      following multiple blood transfusions (author's transl)].

PMID- 4362357
TI  - [Experimental brain gliosarcomas in mice].

PMID- 4362358
TI  - [Autoanalysis of serum lipids of the beta and pre-beta group of lipoproteins].

PMID- 4362360
TI  - [Electron microscopic study of the role of blood platelets in thrombogenesis].

PMID- 4362359
TI  - [Use of polyvinylalcohol (PVA) in obtaining sugar-containing or sugar-free dragee
      coatings].

PMID- 4362361
TI  - [Morphology and histogenesis of reticulohistiocytoma].

PMID- 4362362
TI  - [Enhancement of the immunity against a transplanted cell culture of hepatoma 22a
      in mice].

PMID- 4362363
TI  - [Cytofluorometric study of the DNA content in stomach cancer cells].

PMID- 4362364
TI  - Nutrition in low-birth-weight infants. II. Repeated intravenous injections of fat
      emulsion.

PMID- 4362365
TI  - Impaired interferon response of children with congenital cytomegalovirus disease.

PMID- 4362367
TI  - [Neutralization of bovine papillomatosis virus].

PMID- 4362366
TI  - 99mTC-pertechnetate brain scintigraphy in children.

PMID- 4362368
TI  - [Pharmacological research on maprotiline a new drug with antidepressive effects].

PMID- 4362369
TI  - Reiter's syndrome. A review of current status and a hypothesis regarding its
      pathogenesis.

PMID- 4362370
TI  - The matabolism and control mechanism of human hair follicles.

PMID- 4362371
TI  - Histochemical and ultrastructural study of a peculiar form of
      mucopolysaccharidosis.

PMID- 4362372
TI  - Effects of triethyltin on different ATPases, 5'-nucleotidase and
      phosphodiesterases in grey and white matter of rabbit brain and their relation
      with brain edema.

PMID- 4362373
TI  - Studies in alcoholic liver disease in Britain. I. Clinical and pathological
      patterns related to natural history.
AB  - A group of 258 patients with various forms of alcoholic liver disease-steatosis,
      mild and severe hepatitis, and cirrhosis-has been studied. Severity of disease as
      judged histologically did not correlate very well with clinical presentation
      although signs of hepatocellular failure were certainly commoner in severe
      hepatitis and cirrhosis. Fever, pigmentation, and clubbing were also pointers to
      these two conditions. Alcoholic hepatitis is probably precirrhotic and carries a
      poor prognosis and the best laboratory indicators of this are moderate elevation
      of white cell count and bilirubin. Prognosis in alcoholic liver disease is
      significantly improved by abstinence from alcohol.

PMID- 4362374
TI  - Viral antibodies and autoantibodies in chronic liver disease.
AB  - Our previous observations of highly significant increases in high titre
      antibodies to measles and rubella in patients with chronic active hepatitis have
      been extended and it has been shown that these reactions do not occur in other
      forms of liver disease. Significant increases in antibody titres to
      cytomegalovirus have also been found in patients with chronic active hepatitis
      (p<0.001) and alcoholic and primary biliary cirrhosis (p<0.05). Antibody titres
      to herpes simplex, varicella/zoster, parainfluenza I, and Mycoplasma pneumoniae
      in all forms of chronic liver disease did not differ from controls.
      Immunofluorescent autoantibodies were correlated with the viral antibodies and a
      highly significant correlation with strongly positive antismooth muscle and
      antinuclear antibodies and measles antibody titres in particular was noted. The
      possible significance of this correlation is discussed in terms of the hypothesis
      that the intact liver plays a significant role in the sequestering of antigens.

PMID- 4362375
TI  - The HL-A antigens on human spermatozoa.

PMID- 4362377
TI  - Ovarian pregnancy and the intra-uterine device (IUD). A case report.

PMID- 4362378
TI  - Preparative separation of rabbit seminal plasma and immunochemical study of the
      resulting fractions.

PMID- 4362376
TI  - Biological consequences of population control.

PMID- 4362379
TI  - Zinc and magnesium in human spermatozoa.

PMID- 4362380
TI  - Immunobiological studies with the reproductive organs, adrenals and spleen of the
      female mouse.

PMID- 4362381
TI  - Detection of ovulation by color changes in cervical mucus of crab-eating macaque
      (Macaca fascicularis).

PMID- 4362382
TI  - Daily postcoital tests in the conception cycle during treatment of anovulatory
      women with human gonadotropins.

PMID- 4362383
TI  - Treatment of oligospermia by freezing and concentrating semen.

PMID- 4362384
TI  - Kymographic utero-tubal insufflation in investigating the mode of action of
      modern contraceptives.

PMID- 4362385
TI  - Free amino acids in uterine and blastocoelic fluids in the rabbit as affected by
      ovarian steroids.

PMID- 4362386
TI  - Liver studies during oral contraception with low doses of megestrol acetate.

PMID- 4362387
TI  - A simple method for measuring crystallization of the cervical mucus and its
      application in human sperm migration.

PMID- 4362388
TI  - Medroxyprogesterone acetate as a contraceptive.

PMID- 4362390
TI  - The use of CO2 in the uterine cavity for hysteroscopy.

PMID- 4362389
TI  - Medroxyprogesterone acetate (MPA) for contraception.

PMID- 4362391
TI  - Radiation damage to proteins: the effect of ultra-violet illumination on the
      secondary radical reactions in a single crystal of glycyl-glycine.

PMID- 4362392
TI  - Letter: Radiation chemistry of DNA model compounds. IV. Phosphate ester cleavage
      in radicals derived from glycerol phosphates.

PMID- 4362393
TI  - The human lymphocyte: a model for the study of insulin-receptor interaction.

PMID- 4362394
TI  - An FSH-producing pituitary tumor in a patient with hypogonadism.

PMID- 4362395
TI  - Prolactin and growth hormone in patients with pituitary adenomas: a correlative
      study of hormone in tumor and plasma by immunoperoxidase technique and
      radioimmunoassay.

PMID- 4362396
TI  - Immunoreactive ACTH in cerebrospinal fluid.

PMID- 4362397
TI  - Diurnal plasma testosterone rhythm and the effects of short-term ACTH
      administration on plasma testosterone in man.

PMID- 4362398
TI  - Relation of sleep-entrained human prolactin release to REM-nonREM cycles.

PMID- 4362399
TI  - Low affinity binding of thyroxine to proteins of human serum.

PMID- 4362401
TI  - Herpes simplex virus-specific polypeptides studied by polyacrylamide gel
      electrophoresis of immune precipitates.

PMID- 4362400
TI  - ACTH-induced sodium retention in pregnancy. Role of desoxycorticosterone and
      corticosterone.

PMID- 4362402
TI  - Close linkage between genetic loci controlling response of fowl to subgroup A and
      subgroup C sarcoma viruses.

PMID- 4362403
TI  - Absence of adenovirus-specific repressor in adenovirus tumour cells.

PMID- 4362404
TI  - Effects of adsorption of u.v.-inactivated parainfluenza (Sendai) virus on the
      incorporation of amino acids in animal host cells.

PMID- 4362406
TI  - The detection of foot-and mouth disease virus antigens in infected cell cultures
      by immuno-peroxidase techniques.

PMID- 4362405
TI  - Ferritin-labelled antibody study of RD-114 virus.

PMID- 4362407
TI  - Purification of herpes simplex virus.

PMID- 4362408
TI  - Studies on the lysosomes of L132 cells infected with either rhinovirus type 2 or
      poliovirus type 1.

PMID- 4362409
TI  - Isolation of a virus responsible for an outbreak of acute haemorrhagic
      conjunctivitis in Morocco.
AB  - An epidemic of acute haemorrhagic conjunctivitis occurred in Morocco in 1970-1.
      It was caused by an enterovirus which appeared to be a new antigenic type similar
      to a virus isolated in South East Asia during the same period.

PMID- 4362410
TI  - Experimental pertussis infection in the marmoset: type specificity of active
      immunity.
AB  - ALTHOUGH WE HAVE FAILED TO PRODUCE EITHER PAROXYSMAL COUGH OR VOMITING IN RHESUS
      MONKEYS, CYNOMOLGUS MONKEYS AND MARMOSETS, WE HAVE FOUND IN MARMOSETS SEVERAL
      FEATURES OF PERTUSSIS INFECTION SIMILAR TO THOSE SEEN IN CHILDREN WITH WHOOPING
      COUGH: catarrh, persistence of colonization of the naso-pharynx with Bordetella
      pertussis for 4-11 weeks, change of serotype during colonization and inability of
      type 1 organisms to establish themselves as the predominant serotype.As in
      children, we have found that intramuscular vaccine of type 1,2,3 was more
      effective than type 1,2 in preventing persistent infection with the currently
      prevalent serotypes 1,2,3 and 1,3. A mixed vaccine (1,2,3 and 1,3) seemed to
      produce agglutinin 3 in the serum more consistently than a pure type 1,2,3
      vaccine. The duration of colonization, after naso-pharyngeal challenge, was
      greatly reduced in animals with agglutinin 3.Local immunity, resulting from
      previous infection, was even more effective than a good vaccine in preventing
      subsequent persistent colonization. Marmosets may be useful in studying the
      possible development of aerosol pertussis vaccine for human use.

PMID- 4362411
TI  - Serological evidence of infection with Tana and Yaba pox viruses among several
      species of monkey.
AB  - Sera from cynomolgus monkeys from Malaysia, from Indian rhesus monkeys, from
      various species of monkeys from Africa and from South America have been examined
      for neutralizing antibody to Tanapox and Yaba viruses. No antibody was found to
      either virus in the sera of rhesus monkeys or South American monkeys. A certain
      proportion of sera from cynomolgus monkeys and various species of African monkey
      showed antibody to one or other of the viruses, but few of the positive sera
      showed antibody to both. The results would seem to suggest that infection with
      the two viruses is endemic in African and Malaysian monkeys but does not occur or
      is very rare in Indian rhesus and New World monkeys.

PMID- 4362412
TI  - Differentiation of smallpox and camelpox viruses in cultures of human and monkey
      cells.
AB  - The cytopathic effect of smallpox and camelpox viruses has been compared in cell
      cultures derived from human and monkey tissues. The two viruses could easily be
      distinguished in HeLa, GMK-AH1, BSC-1 and WISH cells, camelpox producing
      multinucleate giant cells and smallpox producing rounding up of individual cells.
      In other cells (LLC-MK2, HEK and 2RhK) the differences were not so marked, and in
      some (VERO, HEL, K and HuTh) no differences were seen.

PMID- 4362413
TI  - Virus isolations from patients in general practice, 1961-71.
AB  - During the period 1961-71 of 1785 viruses isolated from patients in the general
      population 503 (28%) were rhinoviruses, 465 (26%) influenza viruses, 248 (14%)
      enteroviruses, 234 (13%) herpes simplex virus, 132 (7%) parainfluenza viruses,
      129 (7%) adenoviruses and 49 (3%) respiratory syncytial virus. Also isolated were
      18 strains of mumps virus, 7 coronaviruses and 295 streptococci of groups A, C or
      G.Fluctuations were observed in the frequency with which respiratory syncytial
      virus, parainfluenza virus type 2, and the adenoviruses were isolated over the 10
      year period.Influenza viruses types A and B, parainfluenza viruses types 1 and 2,
      respiratory syncytial virus, adenoviruses types 3, 4, 6, 7 and 21, and many
      enteroviruses were all associated with outbreaks.Infections with influenza
      viruses A and B and parainfluenza viruses types 1 and 2 came during the winter,
      whereas those with parainfluenza virus type 3, enteroviruses, and rhinoviruses
      were more frequently seen in the summer and early autumn.

PMID- 4362414
TI  - The distribution in Kenya of bluetongue virus and antibody, and the Culicoides
      vector.
AB  - Sera from domestic cattle, sheep and goats and 11 wild bovid species taken at 41
      locations throughout Kenya were screened for antibody to bluetongue virus using
      the indirect fluorescent antibody method. Positive sera were found at 39
      locations and in all the species tested. The distribution of clinical disease was
      mapped and found to be more restricted than the distribution of antibody.
      Culicoides were collected in light traps at 55 locations throughout Kenya. The
      presumptive vector of bluetongue in Kenya, C. pallidipennis, was the most
      widespread species, found in 38 locations. Both the distribution of antibody and
      Culicoides have been tabulated by ecological zones to demonstrate that bluetongue
      virus in its natural state in cattle and wild bovids is far more widespread than
      clinical bluetongue disease seen in exotic sheep of restricted distribution; and
      that C. pallidipennis has great ecological range.

PMID- 4362415
TI  - Immunocytochemical localization of collagenase in human skin and fibroblasts in
      monolayer culture.

PMID- 4362416
TI  - Mitotic response of normal and psoriatic keratinocytes in vitro to compounds
      known to affect intracellular cyclic AMP.

PMID- 4362417
TI  - Letter: Cyclic AMP for psoriasis.

PMID- 4362418
TI  - Chemical diagnosis of fetal malnutrition.

PMID- 4362419
TI  - Prostaglandins and lipolysis in rat adipose tissue.

PMID- 4362420
TI  - [Wilms' tumor with an atypical course].

PMID- 4362421
TI  - [Insulinomas].

PMID- 4362422
TI  - [Hypersensitivity to synthetic ACTH (Synacthen) in patients with bronchial
      asthma].

PMID- 4362423
TI  - Monolayer culture of normal adult and neoplastic cells of the rat and human
      adrenal cortex.

PMID- 4362425
TI  - Mammography.

PMID- 4362424
TI  - Breast thermography--the mammatherm.

PMID- 4362426
TI  - Angiography of selected pathologic pregnancies.

PMID- 4362428
TI  - Relative locations of rearrangements in the DNA of defective simian virus 40
      (SV40).

PMID- 4362427
TI  - The polypeptide composition of mouse mammary tumor virus.

PMID- 4362429
TI  - Genetic control of expression of endogenous virus genes in chicken cells.

PMID- 4362430
TI  - Inhibition of avian sarcoma virus replication by glucosamine.

PMID- 4362431
TI  - Inhibition of neuraminidase activity by derivatives of 2-deoxy-2,3-dehydro-N
      acetylneuraminic acid.

PMID- 4362432
TI  - Replication of avian sarcoma viruses in chicken macrophages.

PMID- 4362433
TI  - Analysis of RNA associated with the poliovirus RNA replication complexes.

PMID- 4362434
TI  - Homologies among the nucleotide sequences of the genomes of C-type viruses.

PMID- 4362435
TI  - Electron microscopic observations on early events of frog virus 3 replication.

PMID- 4362436
TI  - Sialidase activity of oncogenic cells transformed by herpes simplex virus.

PMID- 4362437
TI  - Replication of a temperature sensitive mutant of simian virus 40 in normal and
      SV40-transformed monkey cells.

PMID- 4362438
TI  - Synthesis of SV40 capsid antigen(s) in heterokaryocytes formed by fusion of
      nonpermissive with permissive cells.

PMID- 4362439
TI  - [Clinical morphological parallels in precancerous diseases and cancer of the
      stomach].

PMID- 4362440
TI  - [Repeated operations in nonorganic retroperitoneal tumors].

PMID- 4362441
TI  - [Kinetics of the cell proliferation of a slowly growing highly differentiated
      mouse hepatoma].

PMID- 4362442
TI  - [Changes in carbohydrate metabolism in the rat kidney sensitized with
      dimethylnitrosamine].

PMID- 4362443
TI  - [Treatment of an extensive turban tumor of the scalp (a single observation)].

PMID- 4362444
TI  - [Detection of type 4 para-influenza in Kiev].

PMID- 4362445
TI  - Editorial: Calcium responses ("calcium spikes").

PMID- 4362446
TI  - Management of vulvar malignancies.

PMID- 4362447
TI  - The reticular activating system revisited.

PMID- 4362448
TI  - Differentiation between the embryonic and tumour specific antigens on chemically
      induced rat tumours.
AB  - The tumour specific antigens and tumour associated embryonic antigens expressed
      on chemically induced rat hepatomata and sarcomata have been shown to be
      different by means of blocking antibody studies. Serum from multiparous female
      rats contained blocking antibody which protected both tumour and embryo cells
      from the in vitro cytotoxic effect of lymph node cells from multiparous donors.
      These sera did not, however, block the cytotoxicity of lymph node cells from
      tumour immune rats for cells of the immunizing tumour. In addition, the tumour
      specific rejection antigens and embryonic antigens have been shown to have
      dissimilar locations in tumour cells.

PMID- 4362450
TI  - Proceedings: A new look at the EB virus and oncogenesis.

PMID- 4362451
TI  - Letter: Oral ulceration and infective agents.

PMID- 4362449
TI  - Additive effect in the induction of kidney tumours in rats treated with
      dimethylnitrosamine and ethylmethanesulphonate.
AB  - Wistar rats were treated with a single dose of 30 mg/kg of DMN or with single
      doses of 100, 200 or 300 mg/kg of EMS. Tumours of the kidney developed in a few
      animals receiving EMS and in 33% of the male and 63% of the female rats treated
      with DMN alone. In the animals receiving DMN and, 8 hours later, a single dose of
      100, 200 or 300 mg/kg of EMS, an additive effect was observed in the induction of
      kidney tumours. This additive effect was more pronounced in female than in male
      rats. Morphologically, the tumours were of epithelial and mesenchymal type with a
      preponderance of the former type. The significance of alkylation of the nucleic
      acids of the kidney observed with these two compounds is discussed in relation to
      the present findings.

PMID- 4362452
TI  - Excess deoxycorticosterone secretion from adrenocortical carcinoma.

PMID- 4362453
TI  - Letter: Poliomyelitis after contact with recently vaccinated infant.

PMID- 4362454
TI  - Letter: Serological tests for amoebiasis.

PMID- 4362455
TI  - Antioestrogens in treatment of breast cancer: value of nafoxidine in 52 advanced
      cases.
AB  - The synthetic non-steroidal antioestrogen nafoxidine (U-11, 100A) was given by
      mouth to 52 women with locally advanced or metastatic breast cancer, in 85% of
      whom the disease had become resistant to, or relapsed after, previous endocrine
      treatment. The objective response rate (complete or partial regression of
      disease) among 48 cases treated for at least four weeks was 37%. Tumours in soft
      tissue seemed to respond better than skeletal metastases. The patients in all but
      one of the 52 cases were postmenopausal. Those who had had an objective response
      to previous hormone treatment had a greater chance of deriving benefit from
      nafoxidine than those who had been resistant to hormone treatment.Side effects of
      nafoxidine were dryness of skin, increased loss of scalp hair, and heightened
      sensitivity to sunlight. None were serious, and they could be lessened by
      protection from solar radiation or a decrease in dosage. No obvious depression of
      thyroid or adrenal function or obvious water retention or masculinization was
      seen. Cataract was a possible complication.This clinical trial was preceded by
      laboratory studies in which a transplantable oestrogen-dependent tumour in the
      Syrian hamster was notably inhibited by the administration of nafoxidine. This
      experimental model may prove useful in screening potentially useful
      antioestrogenic agents against breast cancer before a human trial.

PMID- 4362456
TI  - Central effects of beta-(para-chlorophenyl)-gamma-aminobutyric acid.

PMID- 4362457
TI  - Properties of P503 (prototetrahydroporphyrin IC) in cells and extracts of
      Saccharomyces cerevisiae.

PMID- 4362458
TI  - Formation of estrogen glucosiduronates by human kidney homogenates.

PMID- 4362459
TI  - Letter: Barium suspension versus water-soluble, iodinated compounds in diagnostic
      radiology of the upper gastrointestinal tract.

PMID- 4362460
TI  - Xeroradiography of the breast.

PMID- 4362461
TI  - Cytochemical localization of polysaccharides in Claviceps paspali ultrastructure
      during submerged fermentation of alkaloids.
AB  - Morphological characteristics of two types of elements in the submerged mycelium
      of Claviceps paspali are described. Distribution of polysaccharides in the cell
      wall and cytoplasm was cytochemically determined at the ultrastructural level.
      Polysaccharide deposition into the cell walls was proportional to the increase in
      the alkaloid yield. In the cytoplasm, on the other hand, the presence of
      polysaccharide grains indicated an absence of alkaloid synthesis.

PMID- 4362462
TI  - Bioassay for the isolation of Dictyostelium discoideum mutants deficient in
      extracellular accumulation of cyclic adenosine 3',5'-monophosphate.
AB  - The growth response to external cyclic adenosine 3',5'-monophosphate of a strain
      of Escherichia coli deleted for adenyl cyclase was utilized to screen for mutants
      of Dictyostelium discoideum unable to accumulate this chemical extracellularly.
      The threshold amount of cyclic adenosine 3',5'-monophosphate able to induce
      growth of this bacterium was 3 to 4 mug/ml at 37 C and approximately 25 mug/ml at
      27 C. Conditions are described that permit the detection of as low as 2 mug of
      this chemical at either temperature.

PMID- 4362463
TI  - Examination of isolated yeast cell vacuoles for active transport.
AB  - Isolated vacuoles of the yeast Candida utilis did not show active transport of S
      adenosylmethionine, uric acid, and several amino acids which they concentrate in
      vivo.

PMID- 4362464
TI  - Microtubule assembly and function in Chlamydomonas: inhibition of growth and
      flagellar regeneration by antitubulins and other drugs and isolation of resistant
      mutants.
AB  - The distribution of microtubules in Chlamydomonas reinhardtii suggests that they
      are involved in mitosis, cell and nuclear cleavage, and generation of flagella.
      Vinblastine, colchicine, and podophyllotoxin bind to the protein building block
      of microtubules (tubulin) and prevent normal assembly. Mutants resistant to these
      "antitubulin" drugs are candidates to have alterations in tubulin primary
      structure. We report the ability to inhibit growth, and flagellar regeneration
      after amputation, of: vinblastine, several colchicine derivatives, two water
      soluble derivatives of podophyllotoxin (succinylpodophyllotoxin and
      epipodophyllotoxin thiuronium bromide), and other substances which may interfere
      with flagellar assembly or motility (isopropyl N-phenyl carbamate, 2-methoxy-5
      nitrotropone, chloral hydrate, caffeine, and nickel acetate). The ability of each
      drug to inhibit binding of labeled colchicine or podophyllotoxin to mammalian
      brain tubulin was also determined. The results suggest that only in the cases of
      colchicine, colcemide, and epipodophyllotoxin thiruonium bromide was the toxicity
      to Chlamydomonas mediated by inhibition of tubulin assembly. The requirement for
      high concentrations of colchicine may be due to permeability barriers, since
      colchicine toxicity was potentiated by deoxycholate. Mutants resistant to
      antitubulins were isolated after treatment with methyl methanesulfonate. The
      results with vinblastine were equivocal. Of three mutants resistant to inhibition
      of growth and flagellar regeneration by colchicine, one was also cross-resistant
      to epipodophyllotoxin thiuronium bromide.

PMID- 4362465
TI  - Glutamate synthase: properties of the reduced nicotinamide adenine dinucleotide
      dependent enzyme from Saccharomyces cerevisiae.
AB  - A reduced nicotinamide adenine dinucleotide (NADH)-dependent glutamate synthase
      has been detected and partially purified from crude extracts of Saccharomyces
      cerevisiae. The enzyme is specific for NADH, glutamine, and alpha-ketoglutarate
      (K(m) values of 2.6 muM, 1.0 mM, and 140 muM, respectively) and has a pH optimum
      between 7.1 and 7.7. The stoichiometry of the reaction has been determined as 2
      mol of glutamate synthesized per mol of glutamine consumed. Glutamate synthase
      can be distinguished from either of the glutamate dehydrogenases of yeast on the
      basis of its substrate requirements and behavior during agarose gel and ion
      exchange chromatography. Variations in the specific activity of glutamate
      synthase, which occur in response to changes in the growth medium, are similar in
      character to those observed with the nicotinamide adenine dinucleotide phosphate
      dependent (anabolic) glutamate dehydrogenase.

PMID- 4362466
TI  - Inactivation of isocitrate lyase during myxospore development in Myxococcus
      xanthus.
AB  - The inactivation of isocitrate lyase which occurs during late stages of myxospore
      formation in Myxococcus xanthus was studied. Several findings are reported. (i)
      Protein synthesis is required over a specific time interval in order for
      isocitrate lyase inactivation to occur at a later time. (ii) Metabolic energy is
      required at all times during myxospore development if the inactivation is to
      occur. (iii) It was possible to inhibit protein turnover to a considerable extent
      without affecting the net loss in isocitrate lyase activity.

PMID- 4362467
TI  - Busulfan lung complicated by pneumocystis carinii and cytomegalovirus infection.

PMID- 4362468
TI  - Editorial: The pathogenesis of congenital malformations.

PMID- 4362469
TI  - Congenital choroido-retinitis and cerebral damage from unidentified infective
      agents.

PMID- 4362470
TI  - The dyschromatopsia of pernicious anaemia.

PMID- 4362471
TI  - The influence of the three color vision-mechanisms on the spectral sensitivity of
      the fovea.

PMID- 4362472
TI  - An analysis of colour vision in 314 patients.

PMID- 4362474
TI  - Regulation of the circulation. I.

PMID- 4362473
TI  - Ectopic secretion of calcitonin by oat-cell carcinoma.

PMID- 4362475
TI  - Ultrasonic visualization of the uterus, breast and eye by grey scale echography.

PMID- 4362476
TI  - Radioreceptor assay of human chorionic gonadotropin: detection of early
      pregnancy.
AB  - A rapid, sensitive, and specific radioreceptor assay for the determination of
      human chorionic gonadotropin and luteinizing hormone in plasma is described.
      Plasma membranes of bovine corpora lutea of early pregnancy, which bind
      biologically active labeled human chorionic gonadotropin, have been used as
      receptor. Pregnancy could be detected by assaying the gonadotropin in plasma
      samples obtained from day 6 to 8 after conception.

PMID- 4362477
TI  - Partition of tissue functions in epithelia: localization of enzymes in
      "mitochondria-rich" cells of toad urinary bladder.
AB  - The mucosal epithelium of the toad urinary bladder reabsorbs sodium, acidifies
      the urine, and is responsive to neurohypophyseal hormnones. Mucosal epithelial
      cells, consisting of two major morphologic cell types, "mitochondria-rich" and
      "granular," were removed from the bladder and separated by density gradient
      centrifugation. The mitochondria-rich cells contained three times as much
      carbonic anhydrase activity as the granular cells. Oxytocin caused a 235 percent
      increase in the adenosine 3',5'-monophosphate content of mitochondria-rich cells
      but had no effect on the granular cells. The evidence indicates that the
      mitochondria-rich cell, which accounts for only 15 percent of the mucosal cells,
      plays a major role in the mediation of sodium ion and hydrogen ion transport in
      the toad bladder and is a specific site of action of neurohypophyseal hormones.

PMID- 4362478
TI  - [Neurochemical basis for pathological motor activity].

PMID- 4362479
TI  - [The biochemistry of sleep].

PMID- 4362480
TI  - Amoebiasis.

PMID- 4362481
TI  - [Polarographic determination of the content of certain drug substances in the
      expired air after inhaling them in the form of aerosols].

PMID- 4362482
TI  - The peripheral nerve function in chronic renal failure. 8. Recovery after renal
      transplantation. Clinical aspects.

PMID- 4362483
TI  - The effect of soya lecithin on serum lipid values in type II
      hyperlipoproteinemia.

PMID- 4362484
TI  - Editorial: "Early to bed" or sleep revisited.

PMID- 4362485
TI  - Doxorubicin in treatment of malignant solid tumors in children.

PMID- 4362486
TI  - Parainfluenza virus II and the immunocompromised host.

PMID- 4362487
TI  - Cystosarcoma phyllodes of the breast.

PMID- 4362488
TI  - Distribution of 125I-labeled human growth hormone in immature, hypophysectomized
      rats pretreated with ACTH or unlabeled human growth hormone.

PMID- 4362489
TI  - An ultrastructural analysis of spontaneous activation of hamster eggs aged in
      vivo.

PMID- 4362490
TI  - Patterns of degeneration in the caudal cochlear nucleus of the cat after cochlear
      ablation.

PMID- 4362491
TI  - Effect of glucocorticoids on lysosomes in synovial lining cells in human
      rheumatoid arthritis.

PMID- 4362493
TI  - Generalized melanosis due to malignant melanoma.

PMID- 4362492
TI  - Virus resistance transferred from human rheumatoid cells to rabbit synovial
      cells. II. Cell fusion.

PMID- 4362494
TI  - A temperature-jump study of the reaction between azurin and cytochrome c-551 from
      Pseudomonas aeruginosa.
AB  - Temperature-jump studies on the electron-transfer reaction between azurin and
      cytochrome c-551 clearly reveal two chemical relaxations. The amplitudes of these
      relaxation processes have identical spectral distributions, but the relaxation
      times show different dependences on the reactant concentrations. These findings
      are discussed in terms of possible models.

PMID- 4362495
TI  - Involvement of the superoxide anion in sulphoxidation.
AB  - Sulphoxidation of compounds capable of undergoing biological sulphoxidation has
      been demonstrated in a model system (NADH-phenazine methosulphate-O(2)), known to
      generate superoxide anions (O(2) (-)). Addition of superoxide dismutase to this
      system results in complete inhibition, suggesting the involvement of O(2) (-) in
      sulphoxidation.

PMID- 4362496
TI  - A rapid method for collecting and assaying gradient fractions for radioactive
      macromolecules.
AB  - A rapid method is described for collecting gradients after centrifugation, and
      assaying them for acid-precipitable radioactivity. An entire gradient is
      collected and processed on a single glass-fibre filter disc. This method allows
      one easily to assay six gradients for acid-precipitable radioactivity in less
      than 2h.

PMID- 4362498
TI  - The amino acid sequences of cytochrome c from four plant sources.
AB  - Proposed amino acid sequences of cytochrome c from nasturtium (Tropaeolum majus
      L.), box-elder (Acer negundo L.), elder (Sambucus nigra L.) and parsnip
      (Pastinaca sativa L.) are presented. Because of the very limited amounts of
      cytochrome available from some plant sources, peptides derived from the
      cytochromes c have been sequenced by the semi-quantitative dansyl-Edman technique
      (Gray & Hartley, 1963) without supporting quantitative amino acid analyses.
      Because of the qualitative nature of the work, the sequences proposed must be
      regarded as tentative. Considerations of homology, although useful as a guide,
      have been kept to a minimum in the construction of sequences. Only the nasturtium
      sequence relies on considerations of homology for a complete ordering of the
      peptides. Where material permitted, each residue of a proposed sequence was
      determined at least once from both a tryptic and a chymotryptic peptide.

PMID- 4362497
TI  - The evolutionary stability of cytochrome c-551 in Pseudomonas aeruginosa and
      Pseudomonas fluorescens biotype C.
AB  - Cytochrome c-551 was prepared from nine different strains of Pseudomonas
      aeruginosa and six of Pseudomonas fluorescens biotype C, and their amino acid
      sequences were compared with the sequences previously determined for the
      cytochromes of type strains of each species. The standard of sequence examination
      was such that all single amino acid substitutions, delections or insertions ought
      to have been detected. Balanced double changes in sites in the same part of the
      sequence might have escaped detection. The standard of some of the quantitative
      amino acid analyses was not as high as would be required for the investigation of
      completely unknown sequences. Eight of the Ps. aeruginosa sequences could not be
      distinguished from the type sequence, whereas the ninth had a single amino acid
      substitution. The sequences from Ps. fluorescens biotype C were more varied,
      differing in from zero to four substitutions from the type sequence, with the
      most diverse sequences differing in seven positions. The results for Ps.
      aeruginosa are interpreted as evidence that neutral mutations are not responsible
      for much molecular evolution. The superficially paradoxical differences in the
      results for the two species are discussed.

PMID- 4362499
TI  - Restrained adenyl cyclase in human neutrophils: stimulation of cyclic adenosine
      3':5'-monophosphate formation and adenyl cyclase activity by phagocytosis and
      prostaglandins.

PMID- 4362500
TI  - Single-dose antacid therapy for the prevention of Mendelson's syndrome.

PMID- 4362501
TI  - Proceedings: Influence of halothane on mortality from murine hepatitis virus
      (MHV3).

PMID- 4362502
TI  - Influence of norepinephrine-containing neurons derived from the locus coeruleus
      on lateral geniculate neuronal activities of cats.

PMID- 4362503
TI  - The presence of a factor toxic to pancreatic beta cells in some collagenase
      preparations.

PMID- 4362505
TI  - Clinical staging system for carcinoma of the lung.

PMID- 4362504
TI  - Wilm's tumor--a clinical review.

PMID- 4362506
TI  - Effects of plasma from hypertensive patients on the responses to angiotensin and
      norepinephrine in dogs and rats.

PMID- 4362507
TI  - Comparative study of the effects of metolazone and other diuretics on potassium
      excretion.

PMID- 4362508
TI  - Antiviral drugs.

PMID- 4362509
TI  - Prevalence of antibodies against enteroviruses in the populations of Lucknow.

PMID- 4362510
TI  - Effect of silica on lipid peroxidation in the red cells.

PMID- 4362511
TI  - Adrenocorticotrophic hormone in plasma of mother and newborn.

PMID- 4362512
TI  - Nucleotide sequence relationships of avian RNA tumor viruses: measurement of the
      deletion in a transformation-defective mutant of Rous sarcoma virus.
AB  - Stocks of cloned helper-independent Rous sarcoma virus (RSV) spontaneously
      segregate transformation-defective (td) mutants that appear to have an RNA genome
      composed of smaller subunits than those of the patent virus. Differential
      hybridization and competitive hybridization techniques involving reactions
      between viral RNA and proviral sequences in host cell DNA (under conditions of
      initial DNA excess) were used to measure the extent of the deletion in a td
      mutant of Prague strain (Pr) of RSV (Pr RSV-C). Viral 60 to 70S RNA sequences
      labeled to 1 to 5 x 10(7) counts per min per mug with (125)I were characterized
      with respect to their properties in hybridization reactions and used to reinforce
      data obtained with [(3)H]RNA of lower specific activity. By these techniques,
      about 13% +/- 3% of the sequences Pr RSV-C that formed hybrids with DNA from
      virus-induced sarcomas appeared to be deleted from the genome of td Pr RSV-C.
      Studies comparing hybridization of RNA from Pr RSV-C and td Pr RSV-C with RSV
      related sequences in normal cells, and competition experiments with RNA from the
      endogenous chicken oncornavirus Rous-associated virus type 0 (RAV-0) provided
      evidence that the majority, if not all, of the RNA sequences of Pr RSV-C deleted
      from its transformation-defective mutant are not represented in normal chicken
      DNA. Competition studies with a leukosis virus, RAV-7, indicated this virus also
      lacks a genome segment of about the same size as the deletion in the td mutant.
      Finally, the genome of all three "exogenous" viruses was found to lack a small
      segment (about 12%) of sequences present in the endogenous provirus of RAV-O.

PMID- 4362514
TI  - Effect of D-penicillamine on poliovirus replication in HeLa cells.
AB  - A series of mercaptan compounds were studied with respect to their ability to
      inhibit the growth of poliovirus in cultured cells. Of the compounds tested only
      d-penicillamine possessed antiviral activity. There was no direct effect on the
      virus itself, nor were the processes of adsorption, penetration and uncoating, or
      virus-induced "shut-off" of host cell protein synthesis inhibited. At
      concentrations where there was no effect on host cell RNA or protein synthesis, d
      penicillamine caused a marked inhibition of virus-specific RNA and protein
      synthesis. Although much reduced, the relative concentrations of single-stranded
      and double-stranded viral RNA synthesized in the presence of d-penicillamine was
      unchanged. Similarly, all apparent precursor and cleavage product proteins could
      be synthesized in the presence of the drug. The inhibitory effect was reversible,
      after a lag of 1.5 to 2 h after removal of the drug, and normal yields of virus
      could be obtained. The structural and functional properties of d-penicillamine
      are discussed in relation to requirements for anti-polioviral activity.

PMID- 4362513
TI  - Fate of mRNA of L-cells infected with mengovirus.
AB  - Mengovirus infection of L-cells results in an inhibition of host protein
      synthesis which is detectable in vivo by a decreased rate of incorporation of
      radioactive amino acids into acid-insoluble material and by a concomitant
      reduction in polysome content. The inhibition of host protein synthesis occurs
      early in the infection cycle, at a time when there is little synthesis of viral
      proteins. In this paper the stability of polyadenylic acid [poly(A)]-containing
      mRNA of uninfected L-cells and cells infected with mengovirus is compared. Our
      results suggest that there is no increase in the rate of degradation of cellular
      mRNA upon virus infection. The continued integrity of host mRNA throughout
      infection was verified by acrylamide gel electrophoresis.

PMID- 4362515
TI  - Genetics and physiology of bacteriophage T4 3'-phosphatase: evidence for
      involvement of the enzyme in T4 DNA metabolism.
AB  - Mutants of bacteriophage T4D which fail to induce the deoxyribonucleotide
      specific T4 3'-phosphatase have been isolated. These mutants (T4pseT) grow as
      well as wild-type T4 in most strains of Escherichia coli, but not in the T4
      sensitive "Hospital Strain," CT196, or in a derivative strain, CTr5x. Both the
      formation of infectious centers and the final yield of phage are reduced by 98%
      when CTr5x is infected by T4pseT mutants. The growth defects are accompanied by a
      50% reduction in the rate of T4 DNA synthesis, a decrease in the single-strand
      length of the DNA product to about one-half the mature length, and greatly
      reduced packaging of DNA into phage particles. Introduction of an extra-cistronic
      suppressor mutation (stp) into T4pseT eliminates both the requirement for the T4
      3'-phosphatase in infected CTr5x and the other observed effects of the pseT
      mutations. The pseT gene lies between genes 63 and 31. The stp gene lies in the
      nonessential region between rIIB and ac. Our results suggest that 3'-phosphoryl
      termini can disrupt T4 DNA replication to the extent that T4 3'-phosphatase
      becomes required for phage production.

PMID- 4362517
TI  - Mutant of polyoma virus with impaired adsorption to BHK cells.
AB  - A mutant of polyoma virus PY235 has an impaired adsorption to guinea pig red
      blood cells and BHK-21 hamster cells. Adsorption to 3T3 mouse cells is much less
      inhibited. These altered adsorption properties are responsible for the apparent
      inability of PY235 to cause cell transformation or hemagglutination.

PMID- 4362516
TI  - Transcription and replication of vesicular stomatitis virus: effects of
      temperature-sensitive mutations in complementation group IV.
AB  - Temperature-sensitive (ts) mutants of vesicular stomatitis virus belonging to the
      RNA(-) complementation group IV were investigated under various conditions to
      study both their RNA and protein syntheses. In infected cells maintained at 39.2
      C, viral RNA species were recovered only in the 13 to 15S region of the gradient
      in an amount depending on the ts mutant used. In the presence of cycloheximide at
      39.2 C, the primary transcription was deficient, especially for 28S mRNA
      production. When mutant-infected cells were shifted to nonpermissive temperature,
      a shutoff of 28S mRNA synthesis occurred as a general feature. On the contrary
      under this condition, the two mutants chosen, ts IV100 and ts IV111, behaved very
      differently in their 13 to 15S and 38S RNA production. However, treatment with
      cycloheximide at the time of the transfer to 39.2 C resulted in a similar
      recovery of 13 to 15S RNA in both mutants, whereas the 28S remained very
      depressed. The viral proteins synthesized by cells infected with the same two
      mutants also showed a distinct pattern, especially regarding the N protein; a
      correlation between 38S RNA and protein N syntheses was tentatively drawn. The
      whole set of data suggested that the lesion in group IV mutants concerned a viral
      structural protein required for the process of in vivo transcription and which
      probably intervened in the replication mechanism.

PMID- 4362518
TI  - Comparison of 6-94 virus and Sendai virus RNA by RNA-RNA hybridization.
AB  - The genomic RNA of 6/94 virus, an agent isolated from the brains of multiple
      sclerosis patients, was studied for sequence homology by RNA-RNA hybridization
      with closely related Sendai virus and another paramyxovirus virus, Newcastle
      disease virus. It was found that the genomic RNA of 6/94 virus hybridizes equally
      as well to the virus-specific 18S RNA found in Sendai-infected cells as that of
      Sendai virus.

PMID- 4362519
TI  - Submaxillary gland tumors.

PMID- 4362520
TI  - Adenovirus type 4 in Melbourne, 1969-1971.

PMID- 4362521
TI  - Clinical progress in Crohn's disease.

PMID- 4362522
TI  - Protective effects of BCG and other bacteria against neoplasia in mice and
      hamsters.

PMID- 4362523
TI  - Immunotherapeutic studies in mice with the methanol-extraction residue (mer)
      fraction of BCG: solid tumors.

PMID- 4362524
TI  - Histologic and ultrastructural studies of tumor regression in inbred guinea pigs
      after intralesional injection of Mycobacterium bovis (BCG).

PMID- 4362526
TI  - Effect of adrenalectomy on a diurnal (circadian) rhythm in hypothalamic multiple
      unit activitiy in the female rat.

PMID- 4362525
TI  - The enzymatic ontogeny of neurons and glial cells isolated from postnatal rat
      cerebral gray matter.

PMID- 4362527
TI  - 3H-estradiol distribution in normal and androgenized female rats using an
      improved hypothalamic dissection procedure.

PMID- 4362528
TI  - Photoreduction of horse heart cytochrome c.

PMID- 4362529
TI  - Carotenoid chromophore length and protection against photosensitization.

PMID- 4362531
TI  - Some 'pseudo' and some true endocrine syndromes in cancer.

PMID- 4362530
TI  - Neonatal encephalitis following maternal genital herpesvirus infection.

PMID- 4362533
TI  - The recuperative effects of REM sleep and stage 4 sleep on human performance
      after complete sleep loss: experiment I.

PMID- 4362532
TI  - Cryosurgery in benign conditions of the nose and throat.

PMID- 4362534
TI  - Interaction of REM deprivation and stage 4 deprivation with total sleep loss:
      experiment 2.

PMID- 4362535
TI  - [Study of the radiosensitivity of the nuclear DNA replication process in rat
      ascitic hepatoma].

PMID- 4362536
TI  - [Formation of free radicals in DNA by the simultaneous action of ionizing
      radiation and light].

PMID- 4362537
TI  - A review of 250 cases of Bell's palsy.

PMID- 4362538
TI  - [Decrease in the height of the articular fissure on roentgenograms as a sign of
      aging].

PMID- 4362539
TI  - [Use of a non-opiated analgesic during the acute stage of myocardial infarction].

PMID- 4362540
TI  - [Catheterization of the maxillary sinus in children].

PMID- 4362541
TI  - [Observation of 2 cases of carotid chemodectoma].

PMID- 4362542
TI  - [Cylindroma of the ear].

PMID- 4362543
TI  - Limited proteolysis of alfalfa mosaic virus: influence on the structural and
      biological function of the coat protein.

PMID- 4362544
TI  - Serological interrelationships in the turnip yellow mosaic virus group.

PMID- 4362545
TI  - Identification of a tRNA nucleotidyltransferase and its substrates in virions of
      avian RNA tumor viruses.

PMID- 4362546
TI  - Temperature-sensitive defect of type 2 poliovirus.

PMID- 4362547
TI  - Recombination between temperature-sensitive mutants of herpes simplex virus type
      1.

PMID- 4362548
TI  - RNA polymerase activity and poly(A) synthesizing activity in defective T
      particles of vesicular stomatitis virus.

PMID- 4362549
TI  - Quantitative electron microscopic analysis of the penetration of VSV into L
      cells.

PMID- 4362550
TI  - Infection of human cells with polyoma virus.

PMID- 4362551
TI  - Temperature-sensitive mutants of murine leukemia virus. 3. Mutants defective in
      helper functions for sarcoma virus fixation.

PMID- 4362552
TI  - Enhanced activation of the repressed Epstein-Barr viral genome by inhibitors of
      DNA synthesis.

PMID- 4362554
TI  - Changes in membrane polypeptides that occur when chick embryo fibroblasts and NRK
      cells are transformed with avian sarcoma viruses.

PMID- 4362553
TI  - Synthesis of polyoma virus structural polypeptides in mouse kidney cells.

PMID- 4362555
TI  - Water-soluble contrast media and adhesive arachnoiditis. II. Reinvestigation of
      operated cases.

PMID- 4362556
TI  - Value of exercise at one-half earth gravity in preventing the deconditioning
      effects of simulated weightlessness.

PMID- 4362558
TI  - Letter: Estrogen therapy for periodic fever.

PMID- 4362557
TI  - Ultrastructure and physiological effects of nontobacco cigarettes on Tetrahymena.

PMID- 4362559
TI  - Cellular inflammatory response. Findings in patients with neurological diseases.

PMID- 4362560
TI  - Simulation of cerebral death by succinylcholine sensitivity.

PMID- 4362561
TI  - [Progress in inflammation applicable to chronic evolutive polyarthritis].

PMID- 4362562
TI  - A short, simple synthetic route to 3-dehydrosphinganine and related compounds.

PMID- 4362563
TI  - Silicification of developing internodes in the perennial scouring rush (Equisetum
      hyemale var. affine).

PMID- 4362564
TI  - Morphological and physiological evidence for the development of functional
      neuromuscular junctions in vitro.

PMID- 4362565
TI  - Plasma renin concentration: comparison of angiotensinase inhibitors and
      correlation with plasma renin activity and aldosterone.

PMID- 4362566
TI  - Amylase isoenzymes during viral infections of the pancreas and salivary glands.

PMID- 4362567
TI  - [Evaluation of the role of respiratory viral infections in acute pneumonia].

PMID- 4362568
TI  - [Re-evaluation of certain conclusions concerning the concept of stress].

PMID- 4362570
TI  - Cholestyramine for elevated serum cholesterol.

PMID- 4362569
TI  - [Treatment of myasthenia gravis].

PMID- 4362571
TI  - [Importance of scintiscanning with Tc-99m-labeled pyrophosphate in the early
      diagnosis of bone tumors in pediatrics].

PMID- 4362572
TI  - Hepatic metabolism of estrogens in health and disease.

PMID- 4362573
TI  - Tendon transfers for irreparable peripheral nerve injuries of the upper
      extremity.

PMID- 4362574
TI  - Tendon transfers in combined nerve lesions.

PMID- 4362575
TI  - Skeletal age estimated in a few selected ossification centres of the hand wrist.
      A simple method for clinical use.

PMID- 4362576
TI  - [Diagnosis and current treatment of diabetes insipidus. Apropos of 10 cases].

PMID- 4362577
TI  - [Metabolism of circulating lipids in patients taking oral contraceptives].

PMID- 4362578
TI  - [Primary hypothyroidism of the adult and non-tumoral amenorrhea-galactorrhea
      syndrome. Apropos of a case].

PMID- 4362579
TI  - [Tumoral forms of Waldenstrom's macroglobulinemia. Apropos of a case involving 2
      localisations, orbital and hepatic].

PMID- 4362580
TI  - [Combination of diabetes and scleroderma].

PMID- 4362581
TI  - [Cerebral dematiomycosis (cerebral cladosporiosis). A case in a black
      Senegalese].

PMID- 4362582
TI  - [Adenoma of the left lobe of the liver treated by lobectomy in an 18-months-old
      child].

PMID- 4362583
TI  - [Addison's disease with heart arrest as the initial symptom].

PMID- 4362584
TI  - [Breast neoplasms. A 10-year material].

PMID- 4362585
TI  - Intestinal parasites in Amerindians of the interior of Surinam.

PMID- 4362586
TI  - A comparative study of the rates of metabolism, L.D. 50's and
      antiacetylcholinesterase activities of three diethylphosphoryl esters of
      quinolinols.

PMID- 4362587
TI  - [Prescence of angiotensin receptors in the rat's stomach].

PMID- 4362588
TI  - Adrenoceptors and adenyl cyclase in gills.
AB  - The content of cyclic 3',5'-adenosine monophosphate (cAMP) in the gills of the
      mullet (Mugil capito) has been measured. The basal level was found to be 2.9+/
      0.3 pmol/mg wet weight. When fish were first anaesthetized with MS222 (tricaine)
      and the gills perfused to remove blood, the concentration of cAMP was raised to
      14.3+/-1.9 pmol/mg wet weight.Adrenaline caused a significant increase in cAMP
      content, an effect that was blocked by propranalol, a beta-adrenoceptor
      antagonist. In the presence of the alpha-adrenoceptor block- ing agent
      phentolamine, adrenaline still caused an increase in nucleotide content.The
      results are discussed in relation to adrenaline and the adenyl cyclase system.

PMID- 4362589
TI  - Proceedings: Evidence for a dopaminergic mechanism for modulation of adrenergic
      transmission in the rabbit ear artery.

PMID- 4362590
TI  - Proceedings: Drinking in the cat induced by centrally administered angiotensin.

PMID- 4362591
TI  - Proceedings: Potentiation of dubutyryl cyclic 3'5'-AMP-induced gastric acid
      secretion in rats by non-steroidal anti-inflammatory drugs.

PMID- 4362592
TI  - Sleep induced by small doses of tubocurarine injected into cerebral ventricles of
      dog.
AB  - In unanaesthetized dogs, sleep with the typical sleep pattern in the E.E.G. was
      produced with (+)-tubocurarine when injected in a small dose (500 ng) into, or
      perfused in low concentration (100 ng/ml) through the cerebral ventricles.

PMID- 4362593
TI  - The influence of histamine and other vasoactive substances on contractile
      responses of cat skeletal muscle to acetylcholine.
AB  - 1. The effect of vasoactive substances, chiefly histamine, on contractions of cat
      skeletal muscle evoked by acetylcholine has been studied. For this purpose all of
      these agents were administered intra-arterially to anterior tibialis, chiefly,
      and also to soleus and external rectus muscles in vivo.2. Under these conditions,
      histamine itself never altered the resting tension of the muscle, but always
      enhanced the increase in tension produced by acetylcholine injected shortly
      afterward.3. On the anterior tibialis muscle, it was determined that the
      threshold potentiating dose of histamine was 0.001 mug/kg, and that maximal
      enhancement occurred when 0.1 mug/kg was injected 15 s before fixed, submaximal
      doses of acetylcholine. Injected 15 s before graded doses of acetylcholine,
      histamine 0.1 mug/kg shifted the acetylcholine dose-response curves approximately
      1.5 log units to the left.4. Under similar experimental conditions the
      vasodilator, bradykinin, 0.001-1 mug/kg, and procedures which produce a local
      increase in nutritive capillary blood flow also enhanced acetylcholine-evoked
      contractile responses of the anterior tibialis, whereas the vasoconstrictor,
      angiotensin, 0.001-1 mug/kg, inhibited them.5. The potentiating effect of
      histamine was antagonized by mepyramine, but was undiminished by denervation of
      the muscle either acutely or for 4 days.6. Histamine failed to enhance responses
      of the muscle to electrical stimulation of either the muscle, directly, or its
      motor nerve.7. Histamine also had no effect upon acetylcholine-evoked responses
      of the isolated external rectus muscle in vitro.8. It is suggested that the
      potentiating effect of histamine in vivo is due to its vasodilator action within
      the muscles which, by relaxing arterioles and precapillary sphincters, could
      allow more of the blood-borne acetylcholine to reach more of its receptors on the
      muscle fibres in a given time.

PMID- 4362594
TI  - Developmental change of choline acetyltransferase and acetylcholinesterase in the
      ciliary and the superior cervical ganglion of the chick.

PMID- 4362595
TI  - Effects of taurine on cortical acute epileptic foci.

PMID- 4362596
TI  - Electron histochemical evidence for the role of thiamine pyrophosphatase in
      synaptic transmission.

PMID- 4362597
TI  - Localization of opiate receptor binding in synaptic membranes of rat brain.

PMID- 4362598
TI  - [Vago-aortic sleep after midsagittal section of the brain stem and administration
      of para-chlorophenylalanine, or after destruction of the raphe nuclei].

PMID- 4362599
TI  - [Paradoxical sleep increase triggered by learning, extinction and relearning of a
      response based on a positive reinforcement].

PMID- 4362600
TI  - [Immunization against SV40 tumor virus; antigenic relationship between embryonic
      hamster cells and cells transformed by SV40].

PMID- 4362601
TI  - Maintenance of primary African green monkey kidney (pAGMK) and Vero cells at room
      temperature (25 degrees). A system for virus isolation in community practice.

PMID- 4362602
TI  - [Human cytomegalovirus (CMV) and indirect immunofluorescence in systemic lupus
      erythematosus (SLE)].

PMID- 4362603
TI  - The human spermatozoon. An electron microscopical study including comparative
      details of Macaca arctoides spermatozoa.

PMID- 4362605
TI  - Cytoplasmic control of nuclear activity in preimplantation mouse embryos.

PMID- 4362604
TI  - A protein kinase assayable with intact cells of the cellular slime mold
      Dictyostelium discoideum.

PMID- 4362606
TI  - Inverted caloric nystagmus.

PMID- 4362607
TI  - The importance of dose and proliferation of SV40-transformed cells with different
      oncogenic potentials to the level of tumor immunity.

PMID- 4362609
TI  - EB virus-associated antibodies in Caucasian patients with carcinoma of the
      nasopharynx and in long-term survivors after treatment.

PMID- 4362608
TI  - Further studies on SV40 permissive cell protein factor(s) allowing rescue of
      infectious virus and viral DNA from non-shedder SV40-transformed cells.

PMID- 4362610
TI  - Comparison of EBV neutralization tests based on abortive infection or
      transformation of lymphoid cells and their relation to membrane reactive
      antibodies (anti-MA).

PMID- 4362611
TI  - Epstein-Barr virus: transformation of non-human primate lymphocytes in vitro.

PMID- 4362612
TI  - Effects of adenosine 3'5'-cyclic monophosphoric acid on the morphology, growth
      and cell cycle of Earle's L cells.

PMID- 4362613
TI  - Characteristics of murine C-type viruses. 3. Antigenic conversion and focus
      induction.

PMID- 4362614
TI  - Characteristics of murine C-type viruses. IV. The virus produced by Ehrlich tumor
      cells and it hybrids with mouse L cells.

PMID- 4362615
TI  - The transition from sleep to wakefulness: implications of a study of the
      organization of laboratory dream reports for the psychoanalytic situation.

PMID- 4362616
TI  - A medium for overcoming the in vitro inhibition of Clostridium perfringens by
      Streptococcus faecalis var. zymogenes, and a note on the in vivo interaction of
      the two organisms.

PMID- 4362617
TI  - A method for preparing a pre-reduced, chemically defined, filter sterilized
      medium for growing Clostridium perfringens.

PMID- 4362618
TI  - R factors from Providence.

PMID- 4362619
TI  - The presence and function of cytochromes in Selenomonas ruminantium, Anaerovibrio
      lipolytica and Veillonella alcalescens.

PMID- 4362620
TI  - Subacute sclerosing panencephalitis. Elevated Epstein-Barr virus antibody titers
      and failure of amantadine therapy.

PMID- 4362621
TI  - Induction, detection and characterization of cell differentiation mutants in
      Drosophila.

PMID- 4362622
TI  - The interaction between divalent cations and botulinum toxin type A in the
      paralysis of the rat phrenic nerve-hemidiaphragm preparation.

PMID- 4362623
TI  - [The health system in the U.S.A].

PMID- 4362624
TI  - [Pneumonia during influenza epidemic (November-December, 1971)].

PMID- 4362625
TI  - Replication of the resident repressed Epstein-Barr virus genome during the early
      S phase (S-1 period) of nonproducer Raji cells.
AB  - Replication of the resident repressed Epstein-Barr virus genome in synchronized
      nonproducer Raji cells was shown to occur during the early S phase (S-1 period)
      by hybridization of cell DNA with virus-specific complementary RNA (cRNA). The S
      1 period was previously identified as the critical period for virus activation
      induced by thymidine analogues. The findings reported here and elsewhere are
      consistent with the proposal that: (i) virus activation is initiated at or near
      the site of association of the resident viral genome with cell DNA, (ii)
      replication of the resident virus genome in nonactivated cells is under cell
      control mechanisms, and (iii) the resident virus genome is physically associated
      with early replicating cell DNA.

PMID- 4362626
TI  - In vitro activation of the transcription of araBAD operon by araC activator.
AB  - The transcription of araBAD operon requires araC activator and cyclic AMP. D
      Fucose inhibits ara mRNA synthesis. Our results indicate that the positive
      control by araC activator is exerted at the level of transcription.

PMID- 4362627
TI  - Intracellular cyclic AMP concentration responds specifically to growth regulation
      by serum.
AB  - Intracellular concentrations of cyclic AMP increase when cells are deprived of
      serum. Studies with the mouse fibroblast line 3T3, an SV40-transformed subline of
      3T3, and six different revertant lines derived from this clone show that a marked
      increase in cyclic AMP occurs only when the serum concentration is reduced below
      the minimum necessary for growth of a given line. Conversely, density-dependent
      inhibition of growth is not accompanied by an increase in cyclic AMP
      concentration in any line.

PMID- 4362628
TI  - Fractionation of DNA on hydroxyapatite with a base-specific complexing agent.
AB  - We describe a chromatographic technique for separating mixtures of DNA of varying
      G + C content. The method employs a specially prepared high-capacity
      hydroxyapatite and a G.C-specific DNA ligand (2-methyl-3-amino-7-dimethylamino-5
      phenyl-phenazinium cation, abbreviated PNR). DNA molecules rich in G.C pairs bind
      larger amounts of this dye and are eluted earlier from the hydroxyapatite column
      than are molecules rich in A.T pairs. The dye can easily be removed from DNA by
      dialysis or solvent extraction after the chromatographic separation. The
      resolution of the method approaches that of CsCl density gradient separation, and
      the capacity of the column is much larger than that of a typical density gradient
      experiment. Elution of the DNA is not dependent on molecular weight, so samples
      of different molecular weight can be separated on the basis of G + C content. The
      technique should be especially useful for separating G.C-rich minor components
      from DNA obtained form eukaryotic cells, as demonstrated by a fraction of DNA
      from calf thymus.

PMID- 4362629
TI  - Reversion of a Chinese hamster cell auxotrophic mutant.
AB  - A mutant cell strain derived from a Chinese hamster line by mutagenesis with
      ethylmethane sulfonate requires glycine for growth. In the wild type, glycine
      synthesis is catalyzed by serine hydroxymethyltransferase (EC 2.1.2.1). Cell
      fractionation by differential centrifugation and isopycnic sucrose gradient
      analysis reveals that the enzyme activity is found in both the mitochondrial and
      cytosol fractions. The specific activity in the mitochondrial fraction is about
      20 times higher than in the cytosol, and is much more stable to thermal
      inactivation. The glycine-requiring mutant has lost all of the mitochondrial
      enzyme activity, while retaining the cytosol activity. The mutant is very stable
      but can be induced to revert by several chemical mutagens. One glycine
      independent revertant induced by ethyl methane sulfonate was studied in detail.
      Serine hydroxymethyltransferase activity is again present in the mitochondrial
      fraction, at about [unk] of the wild-type level. However, the revertant
      mitochondrial enzyme exhibits an altered thermal sensitivity, with a half-life at
      45 degrees of 55 min as compared to 180 min in the wild type. The half-life for
      the cytosol enzyme in all three strains is 7 min. Mixing experiments demonstrate
      that the heat lability of the revertant enzyme is not due to a dissociable factor
      in the extract. The data are consistent with the idea that the original mutation
      occurred in the structural gene for one isozyme of the enzyme and that the
      revertant has undergone a second mutation in this gene, partially restoring
      enzyme activity.

PMID- 4362630
TI  - Parathyroid hormone receptors of renal cortex: specific binding of biologically
      active, 125I-labeled hormone and relationship to adenylate cyclase activation.
AB  - Biologically active (125)I-labeled bovine parathyroid hormone (prepared by
      electrolytic iodination) and its synthetic NH(2)-terminal (1-34) biologically
      active fragment bound rapidly and specifically to a purified plasma membrane
      preparation from bovine renal cortex. Binding of labeled intact hormone or
      labeled NH(2)-terminal (1-34) peptide was inhibited competitively by unlabeled (1
      34) peptide in the same range of concentrations that activated renal cortical
      3':5'-adenylate cyclase (EC 4.6.1.1) in these membranes. The concentrations of
      synthetic (1-34) peptide for half-maximal inhibition of binding of labeled
      hormone as well as half-maximal activation of the enzyme were about 0.6 muM (2.5
      mug/ml). Therefore it is likely that the binding activity studied represents a
      physiologically important renal receptor for parathyroid hormone. Biologically
      inactive (oxidized) forms of parathyroid hormone and (1-34) NH(2)-terminal
      peptide as well as calcitonin, glucagon, insulin, and epinephrine failed to
      competitively inhibit the binding of labeled (1-34) parathyroid hormone or
      activate adenylate cyclase in the renal cortical membrane preparation.
      Observations with the NH(2)-terminal (1-34) biologically active fragment of
      parathyroid hormone suggest that the COOH-terminal region of the molecule is not
      required for receptor binding.

PMID- 4362631
TI  - Introduction of specific cleavages into RNAs of RNA bacteriophages for
      determination of base sequences.
AB  - Large fragments of R17, MS2, and Qbeta RNAs were obtained reproducibly by limited
      digestion by ribonuclease T1. After digestion of R17 and MS2 RNAs, two pairs of
      large fragments were obtained that probably resulted from specific cleavages of
      the whole molecules. The cleavages of MS2 RNA were produced at points 36 and 47%
      from the 5' end.

PMID- 4362632
TI  - The roles of the lambda c3 gene and the Escherichia coli catabolite gene
      activation system in the establishment of lysogeny by bacteriophage lambda.
AB  - Maximum lysogenization of E. coli by bacteriophage lambda requires both the
      lambdacIII gene function and the host catabolite gene activation system mediated
      by adenosine 3':5'-cyclic monophosphate. Whereas considerable lysogenization
      occurs in the presence of either system alone, lysogenization is absolutely
      prevented in the absence of both systems. Neither system is, however, required
      for efficient lysogenization when the host bears an hfl(-) mutation. It is argued
      that the normal function of these two systems is to negate the antagonistic
      effect of the Hfl(+) protein upon lysogenization. It is further argued that both
      the lambdacIII gene function and the Hfl(+) protein do not directly affect the
      host catabolite gene activation system.

PMID- 4362633
TI  - Association of DNA-dependent and  -independent ribonucleoside triphosphatase
      activities with dnaB gene product of Escherichia coli.
AB  - Preparations of E. coli dnaB gene product contain ribonucleoside triphosphatase
      activity that is stimulated 10-fold by DNA. The products of the triphosphatase
      activity are nucleoside diphosphates and P(i). The dnaB complementing activity in
      the varphiX174 DNA-dependent system and these triphosphatase activities copurify
      over the last 20-fold of an extensive (about 40,000-fold) purification procedure.
      Acrylamide gel electrophoresis of the purified material shows a single band of
      protein coincident with eluted dnaB complementing and DNA-dependent and 
      independent nucleoside triphosphatase activities.

PMID- 4362634
TI  - Familial hypercholesterolemia: defective binding of lipoproteins to cultured
      fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl
      coenzyme A reductase activity.
AB  - Monolayers of cultured fibroblasts from normal human subjects bind (125)I-labeled
      low-density lipoproteins with high affinity and specificity. High affinity
      binding of similar magnitude was not observed in cells from five unrelated
      subjects with the homozygous form of familial hypercholesterolemia. In normal
      cells incubated at 37 degrees , the binding sites were saturated at a low-density
      lipoprotein concentration of 20 mug/ml. A maximum of approximately 250,000
      molecules could be bound to each cell. Whole serum and very-low-density
      lipoproteins displaced (125)I-labeled low-density lipoproteins from the binding
      sites, but high-density lipoproteins, the lipoprotein-deficient fraction of
      serum, and abetalipoproteinemic serum did not. This binding appears to be a
      required step in the process by which low-density lipoproteins normally suppress
      the synthesis of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase, the rate
      controlling enzyme in cholesterol biosynthesis. The demonstration of a defect in
      binding of low-density lipoproteins to cells from subjects with the homozygous
      form of familial hypercholesterolemia appears to explain the previously reported
      failure of lipoproteins to suppress the synthesis of this enzyme and hence may
      account for the overproduction of cholesterol that occurs in these cultured
      cells.

PMID- 4362636
TI  - Prediction of secondary structure of proteins. A comparison of the phi, psi
      angles previously predicted for cytochrome c with recent x-ray crystallographic
      findings.
AB  - Newer data from the x-ray crystallographic studies of tuna heart ferrocytochrome
      c have increased the number of residues in alpha-helical segments. This provided
      an objective test of our method of predicting varphi,Psi values for cytochrome c
      using the sequences of 18 cytochromes c and twenty 20 x 20 tables for the
      varphi,Psi values of tripeptides in 10 other proteins whose three-dimensional
      structures were known from x-ray crystallographic studies. Of the 32 residues now
      considered from x-ray data to be in alpha-helices, 27 had been predicted to be in
      the alpha-helical domain.

PMID- 4362637
TI  - Electron spin resonance studies of erythrocytes from patients with myotonic
      muscular dystrophy.
AB  - Electron magnetic resonance experiments have demonstrated that spin-labeled
      myotonic erythrocyte membranes have spectra that are recognizably different from
      those of normal erythrocytes. The spin label incorporated in the erythrocyte
      membranes of patients having myotonic muscular dystrophy is apparently located in
      a less polar and somewhat more fluid region than the label in a normal membrane.
      Although the mechanisms of molecular interaction and their relationship to
      enzymatic differences is unclear, the results lend confirmation to the suggestion
      that myotonic muscular dystrophy may be a disease resulting from a basic membrane
      abnormality.

PMID- 4362635
TI  - Alteration of vein cyclic 3':5' nucleotide concentrations during changes in
      contractility.
AB  - The relative changes in vascular tissue levels of cyclic 3':5'-guanosine
      monophosphate (cGMP) and cyclic 3':5'-adenosine monophosphate (cAMP) were
      determined in bovine and canine vein strips that were quickfrozen during changes
      in contractility elicited by prostaglandins (PG) or isoproterenol. Prostaglandin
      F(2alpha)-induced venoconstriction was associated with increased vascular tissue
      levels of cGMP and increased ratios of cGMP to cAMP concentrations, but no
      consistent qualitative change in cAMP levels. In contrast, vein cAMP
      concentrations were increased during administration of the vasodilators PGE(2)
      and isoproterenol. The results suggest possible opposing roles for the two cyclic
      nucleotides in vasomotion.

PMID- 4362638
TI  - The electrostatic basis of Mg++ inhibition of transmitter release.
AB  - The inhibition by Mg(++) of stimulus-evoked transmitter release is attributed to
      a decrease in surface potential, Psi(0), on the outer surface of the presynaptic
      terminal and hence a lower surface calcium concentration, [Ca(++)](0). Data on
      the frog neuromuscular junction are quantitatively fit by assuming that there is
      a negative charge density, sigma, on the outer surface of the presynaptic
      terminal of 6.5 x 10(13) charges per cm(2) and that simple diffuse double layer
      theory is applicable. No specific binding of Mg(++) or Ca(++) is required.
      Without any additional assumptions, the inhibitory effect of univalent cations is
      also quantitatively predicted.

PMID- 4362639
TI  - Expression of differentiated functions in hepatoma cell hybrids: high frequency
      of induction of mouse albumin production in rat hepatoma-mouse lymphoblast
      hybrids.
AB  - We have studied the production of serum albumin by somatic hybrids between well
      differentiated 2s and 1s rat hepatoma cells (Faza), which produce serum albumin,
      and sub-diploid mouse leukemic lymphoblasts (Lc), which do not produce albumin.
      We determined the rat or mouse origin of the albumin by double immunodiffusion,
      using immuno-adsorbed noncrossreacting antisera. Each of 12 karyologically
      identified 2s hybrid clones (Lc2F) produces both rat and mouse albumin. Moreover,
      unlike 1s hybrids reported previously, eight of nine 1s hybrids (LcF) also
      produce mouse albumin; six of them produce rat albumin as well. One clone from
      the 1s cross produces only rat albumin.

PMID- 4362640
TI  - The isolation of simian virus 40 variants with specifically altered genomes.
AB  - Serial passage of simian virus 40 (SV40) at high multiplicity of infection leads
      to the emergence of variants with deleted, substituted, and/or duplicated DNA.
      Individual variants have been cloned by selective complementation with
      temperature sensitive SV40 mutants, or nonselectively by coinfection of cells
      with wild-type helper virus. In each case, the presence of variants was detected
      by the appearance of discrete short viral genomes in infected cell lysates. Such
      short genomes, isolated by agarose gel electrophoresis, were shown to be
      specifically altered by comparing the electrophoretic pattern of their DNA
      fragments produced by Haemophilus influenzae restriction endonuclease with the
      pattern of fragments from parental DNA. In addition to defective variants, one
      infectious variant that had an additional segment of DNA within its genome was
      isolated.

PMID- 4362641
TI  - Human antigen and enzyme markers in man-Chinese hamster somatic cell hybrids:
      evidence for synteny between the HL-A, PGM3, ME1, and IPO-B loci.
AB  - In man-Chinese hamster somatic cell hybrids the segregation of the loci for 27
      human enzyme markers and the species-specific surface antigens, including the HL
      A histocompatibility antigens, was studied. The results show a synteny of the
      human loci for phosphoglucomutase 3, cytoplasmic malic enzyme, tetrameric
      indophenol oxidase, and HL-A. Furthermore, evidence is presented that the loci
      for the human species-specific antigens are distributed over several chromosomes.

PMID- 4362642
TI  - Identification of a high affinity nuclear acceptor site for estrogen receptor of
      calf uterus.
AB  - By means of affinity chromatography, specific nuclear acceptor sites for
      estradiol receptors are identified in a fraction that can be solubilized from
      purified nuclei with 2 M NaCl. Interaction between these acceptor sites and crude
      or partially purified estradiol receptor shows a high association constant (over
      10(9) M). Receptor-acceptor interaction is dependent on physiological
      concentrations of 17beta-estradiol; it is disrupted by high ionic strength. The
      nuclear acceptor sites appear to be protein in nature and exist in 5- to 10-fold
      excess over the estrogen binding sites present in the cytosol. Single- or double
      stranded DNA does not bind estrogen-receptor complexes. Acceptor sites appear to
      be associated with basic nuclear proteins as judged by hydroxyapatite
      chromatography. The nuclear acceptor sites probably represent less than 0.1% of
      the purified basic proteins from the nucleus.

PMID- 4362643
TI  - Lipid-protein interactions in high density lipoproteins.
AB  - Delipidated high density lipoprotein (apo-HDL), isolated apolipoproteins apoA-I
      and apoA-II, S-carboxymethylated apoA-II, apoC-III, the NH(2)- and COOH-terminal
      CNBr peptides of apoA-II, and the COOH-terminal CNBr peptide of apoA-I were
      recombined in vitro with [N-C(3)H(3)-choline]phosphatidylcholine (PC) and [N
      (14)CH(3)-choline]sphingomyelin (SPM). The lipid-protein complexes were analyzed
      by ultracentrifugal flotation, agarose gel chromatography and circular dichroism.
      ApoHDL, apoA-II, and S-carboxymethylated apoA-II readily recombined with PC or
      SPM to form particles that were similar in size to native HDL. The COOH- but not
      the NH(2)-terminal CNBr peptide of apoA-II recombined with lipid. ApoA-I and the
      COOH-terminal CNBr peptide of apoA-I, however, recombined with PC or SPM to only
      a limited extent, suggesting that protein-protein interactions between apoA-I and
      apoA-II are important in the integration of apoA-I into recombined lipoprotein
      particles. Analysis of the recombined lipid-protein complexes by circular
      dichroism indicated that there was an increase in helical structure concomitant
      with lipid-protein binding. The reconstituted particles had many of the physical
      and chemical properties of the native lipoprotein.

PMID- 4362644
TI  - Genetic differentiation within and between species of the Drosophila willistoni
      group.
AB  - We describe allelic variation at 28 loci in six Caribbean populations of four
      sympatric species of Drosophila. Within any one species the allelic frequencies
      are very similar from population to population, although there is evidence of
      local as well as regional genetic differentiation. The genetic distance is
      greater between populations from different islands than between populations of
      the same island. When the allelic frequencies are compared between different
      species, a remarkable pattern appears. In any pair of species nearly half of the
      loci have essentially identical allelic frequencies, while nearly the other half
      of the loci have different alleles and in different frequencies. The loci with
      nearly identical allelic frequencies are different when different pairs of
      species are compared. The patterns of allelic variation within and between
      species are inconsistent with the hypothesis that the variation is adaptively
      neutral. Migration or mutation cannot explain the patterns of genetic variation,
      either. Balancing natural selection is the main process maintaining protein
      polymorphisms in natural populations.

PMID- 4362645
TI  - Current concepts in diagnosis of insulinoma.

PMID- 4362646
TI  - [Morbid anatomy of bronchial carcinoma (author's transl)].

PMID- 4362647
TI  - [Radiological signs of bronchial carcinoma in thorax general radiograph (author's
      transl)].

PMID- 4362649
TI  - Prevalence and intensity of intestinal parasitism on Talim Island, Binangonan,
      Rizal, Philippines.

PMID- 4362648
TI  - Treatment of common enteric parasites.

PMID- 4362650
TI  - Life cycle of the murine mammary tumor virus, and a comparison with similar forms
      reported in human mammary carcinomas.

PMID- 4362651
TI  - Common antigens in herpesviruses from divergent species of animals.

PMID- 4362652
TI  - [Principles and concept 1973 of the "cancer multistep-therapy" with optimal time
      schedules after therapy. Theoretical viewpoints. 1].

PMID- 4362653
TI  - Further evidence for a humoral control of factor VIII plasma levels.

PMID- 4362654
TI  - Effect of corticosteroids upon fibrinogen metabolism in rabbits.

PMID- 4362655
TI  - [Letter: The after-treatment of fractures is paid too little attention and
      demands better cooperation between patient and physician and between surgeon and
      practitioner than is common today].

PMID- 4362656
TI  - [Anatomy and pathology of the peripheral nerves].

PMID- 4362657
TI  - [Pain. Mechanisms, manifestations and therapeutic principles].

PMID- 4362658
TI  - [Streptozotocin therapy for metastasizing insuloma].

PMID- 4362659
TI  - [Letter: Therapy of brain neoplasms].

PMID- 4362661
TI  - [Genetic principles of various symptoms related to maturing (as based on studies
      in twins)].

PMID- 4362660
TI  - [Serum complement components C3, C4 and immunoglobulins IgG, IgM, IgA after renal
      transplantation (author's transl)].

PMID- 4362663
TI  - Adenoid cystic carcinoma of the breast.

PMID- 4362664
TI  - Evidence that the polyadenylic acid segment of "35S" RNA of avian myeloblastosis
      virus is located at the 3'-OH terminus.

PMID- 4362662
TI  - Adrenocortical function of patients using oral contraceptives.

PMID- 4362665
TI  - Systematic identification of aldehydes and aldehyde-derived crosslinks in elastin
      by methods including a modified Strecker reaction.

PMID- 4362666
TI  - [Physiopathological and anatomoclinical bases of surgery of duodenal ulcer
      (cortical, diencephalic, hypophyseal, pancreatic, (adrenal) and vagogastric
      pathogenic hypothesis)].

PMID- 4362667
TI  - The relationship of polyoma virus-induced tumor (T) antigen to activation of DNA
      synthesis in rat myotubes.

PMID- 4362668
TI  - Expression of liver phenotypes in cultured mouse hepatoma cells: synthesis and
      secretion of serum albumin.

PMID- 4362669
TI  - Management of travellers' diarrhoea.

PMID- 4362670
TI  - [Diagnosis of Wilms' tumor].

PMID- 4362671
TI  - [Treatment of Wilms' tumor in childhood].

PMID- 4362672
TI  - [Diagnosis and therapy of arterial hypertension. Significance of the renin
      angiotensin-aldosterone system in differential diagnosis and therapy].

PMID- 4362673
TI  - Abnormal degradation of macroaggregated albumin particles in patients with
      asthma.

PMID- 4362674
TI  - Epidermal adenyl cyclase of human and mouse. A study of the atopic state.

PMID- 4362675
TI  - Chemodectoma of the urinary bladder in a dog.

PMID- 4362676
TI  - Cobamides and ribonucleotide reduction. XII. The electron paramagnetic resonance
      spectrum of "active coenzyme B12".

PMID- 4362677
TI  - The biosynthesis of folic acid. XII. Purification and properties of
      dihydroneopterin triphosphate pyrophosphohydrolase.

PMID- 4362678
TI  - The molecular properties of ApoA-I from human high density lipoprotein.

PMID- 4362679
TI  - Neurospora crassa protein kinase. Purification, properties, and kinetic
      mechanism.

PMID- 4362680
TI  - Glucocorticoid receptors in fetal and adult rabbit tissues.

PMID- 4362681
TI  - The b-cytochromes of plant mitochondria. A spectrophotometric and potentiometric
      study.

PMID- 4362682
TI  - The generation of hydrogen peroxide, superoxide radical, and hydroxyl radical by
      6-hydroxydopamine, dialuric acid, and related cytotoxic agents.

PMID- 4362683
TI  - Structural analysis of ribosomal 28 S ribonucleic acid of Novikoff hepatoma
      cells.

PMID- 4362684
TI  - Immunological specificities of lysine-rich histones from tumors.

PMID- 4362686
TI  - The kinetic mechanism of glycerokinase.

PMID- 4362685
TI  - Role of photophosphorylation coupling factor in energy conversion by depleted
      chromatophores of Rhodospirillum rubrum.

PMID- 4362687
TI  - The inhibition of acetate, pyruvate, and 3-phosphogylcerate kinases by chromium
      adenosine triphosphate.

PMID- 4362688
TI  - The specificity of chromium nucleotides as inhibitors of selected kinases.

PMID- 4362689
TI  - The structure of the heme crevice of ferric cytochrome c alkylated at methionine
      80.

PMID- 4362690
TI  - Alkaline isomerization of oxidized cytochrome c. Equilibrium and kinetic
      measurements.

PMID- 4362691
TI  - Primary epithelioid sarcoma of the hand and forearm. A review of thirteen cases.

PMID- 4362692
TI  - Effect of cAMP on nucleoside metabolism. I. Effect on thymidine transport and
      incorporation in monkey cells (CV-1).

PMID- 4362693
TI  - The role of humoral factors in the regression of leukemia in chickens as measured
      by in vitro colony formation.

PMID- 4362695
TI  - Viral probe into the events of cellular (in vitro) aging.

PMID- 4362694
TI  - Inhibition of development of transformation by Rous sarcoma virus in cultures of
      high cell density.

PMID- 4362696
TI  - Pyrimidine excretion by cultured fibroblasts: effect of mutational deficiency in
      pyrimidine salvage enzymes.

PMID- 4362697
TI  - The influence of sex steroids on calcium- and magnesium-induced mitogenesis in
      isolated rat thymic lymphocytes.

PMID- 4362698
TI  - A new rapid method for estimation of urinary pregnanediol.

PMID- 4362699
TI  - Proceedings: Release of adrenocorticotrophin from the isolated pituitary gland of
      the rat: studies with theophylline.

PMID- 4362700
TI  - Ultrastructural studies of the dying-back process. I. Peripheral nerve terminal
      and axon degeneration in systemic acrylamide intoxication.

PMID- 4362701
TI  - Lower motor neuron degeneration associated with type C RNA virus infection in
      mice: neuropathological features.

PMID- 4362702
TI  - Lipogenesis and insulin sensitivity of single fat cells.
AB  - 1. A method for measuring the lipogenesis from [(14)C]glucose by single fat cells
      is described: (i) after incubation with ;carrier-free' [U-(14)C]glucose (0.55 mu
      mole/ml.), collagenase-isolated fat cells were fixed with osmium tetroxide; (ii)
      similarly incubated pieces of epididymal fat pads were treated with osmium
      tetroxide for 90 sec, whereby only the superficial cells are fixed, and the
      tissue was then disintegrated by shaking with collagenase. The osmium-fixed free
      cells were washed, sucked into a micropipette, measured under a microscope and
      assayed individually for (14)C-activity.2. There was a quantitative recovery of
      (14)C-lipid activity from osmium-fixed single cells.3. Both collagenase-isolated
      cells and in situ fixed surface cells were normally distributed with respect to
      diameters (for both cell groups from ad lib. fed rats of ca. 110 g; mean
      diameter, about 55 mum; S.D. about 7 mum).4. Frequency distribution curves
      (number of fat cells versus (14)C-lipogenesis per cell) were asymmetric and very
      broad (coefficient of variation about 50%) for collagenase-isolated cells
      incubated with insulin (10(3) mu-u./ml.). Frequency distribution curves for
      surface cells obtained from similarly incubated pieces of epididymal fat pads
      showed a coefficient of variation of the same magnitude, whereas the mean
      lipogenesis of these cells was only about one third of that of the isolated
      cells.5. Collagenase-isolated cells incubated in the presence of insulin (10(3)
      mu-u./ml.) showed a weak but highly significant positive correlation between fat
      cell diameter and (14)C-lipogenesis (eight rats, r about 0.5 and P < 0.001 for
      each rat). Analysis of the relationship: lipogenesis = k x diameter to the
      exponent of beta showed that the estimates of beta varied significantly from rat
      to rat (range: 1.3-2.9). Similar correlations between cell size and lipogenesis
      were found both for cells incubated with insulin in various submaximal
      concentrations and for cells incubated without insulin.6. Small and large cells
      from the same rat were equally sensitive to insulin.7. Statistical analysis of
      frequency distribution curves (number of cells versus (14)C-lipogenesis per unit
      surface area) representing cells from the same rat incubated with insulin 0, 2.5,
      5, 10, and 10(3) mu-u./ml., respectively, suggests that insulin exerts a graded
      influence on the lipogenesis of each fat cell.

PMID- 4362704
TI  - The use of closed-circuit television in marital therapy.

PMID- 4362703
TI  - Organization of corticofugal neurones in somatosensory area II of the cat.
AB  - 1. This investigation had two main objectives: first to determine whether or not
      motor activity could be elicited by localized intracortical stimulation in
      somatosensory area II of the cat, and secondly to identify, by antidromic
      stimulation, neurones which projected to subcortical structures and to study
      their afferent input.2. Although arm movements could be elicited in most cats by
      intracortical train stimulation with tungsten micro-electrodes, the lowest motor
      thresholds were much higher than the lowest thresholds for the primary motor area
      under similar experimental conditions. Facial responses were evoked at lower
      stimulus thresholds, but the threshold decreased steadily as successive
      stimulation tracks approached the coronal face area. Previously observed
      responses to prolonged surface stimulation could have been caused by
      intracortical spread of excitation or by escape of stimulus to the primary area,
      especially the face area.3. Neurones with corticofugal axons projecting to bulbar
      and spinal levels were first identified by their antidromic response to
      stimulation of the cerebral peduncle. Each was further tested by stimulation of
      the cervical corticospinal tract, and the dorsal column nuclei. Their receptive
      fields were then recorded.4. It was possible to classify the neurones into four
      main categories: (i) non-descending neurones: neurones not activated
      antidromically by any of the subcortical stimulating electrodes. The majority of
      these neurones had very small (lemniscal type) receptive fields, (ii)
      corticobulbar neurones: these were invaded antidromically by stimulation of the
      peduncle but not by spinal or dorsal column nuclei stimulation. They had
      ;stocking-like' or larger receptive fields; (iii) cortico-spinal neurones:
      neurones driven antidromically by stimulation of corticospinal fibres.
      Characteristically, these neurones had large confluent fields, often bilateral.
      Very few had receptive fields of the lemniscal type; (iv) neurones invaded by
      dorsal column nuclei stimulation: the number of such units was extremely low and
      their receptive fields were large or ;stocking-like'.5. The results indicate that
      somatosensory area II in the cat does not exert an independent motor control of
      spinal neurones, and it is thought that corticofugal neurones of SII are involved
      in the control of somatosensory transmission rather than having a direct motor
      function.

PMID- 4362705
TI  - The family as a system: a network of relationships.

PMID- 4362707
TI  - The role of the nurse in counseling the alcoholic.

PMID- 4362706
TI  - Intervention in a pathological cycle of anxiety.

PMID- 4362708
TI  - The process of implementing the nurse's role in a neighborhood center.

PMID- 4362709
TI  - International trends: how to manage health--a summary of WHO technical
      discussions.

PMID- 4362710
TI  - Strategies for interviewing in language and thought disorders.

PMID- 4362711
TI  - Speaking out on: increasing costs and reducing patient care in the name of
      patient protection or standards.

PMID- 4362712
TI  - Psychiatric drugs and trends; new regulations on vitamins and minerals.

PMID- 4362713
TI  - Geriatrics: CPI consumer price index.

PMID- 4362714
TI  - Incidence and distribution of neutralizing antibodies to porcine enteroviruses in
      Southern Africa.

PMID- 4362716
TI  - Editorial: Varicella-zoster infections: zoster immune globulin.

PMID- 4362717
TI  - Cancer of the gastrointestinal tract. Histogenesis and premalignant lesions.

PMID- 4362718
TI  - Cancer of the gastrointestinal tract. Diagnostic radiology.

PMID- 4362715
TI  - Causes of variation of copper, iron, manganese, zinc and magnesium levels in
      bovine livers. 1. Determination of trace elements by atomic absorption
      spectrophotometry.

PMID- 4362720
TI  - In vitro antimicrobial susceptibility testing. Clinical implications and
      limitations.

PMID- 4362719
TI  - Untoward effects of antimicrobial agents on major organ systems.

PMID- 4362721
TI  - Antimicrobial drugs for treatment of infections caused by aerobic gram-negative
      bacilli.

PMID- 4362722
TI  - Viral infections of the central nervous system.

PMID- 4362723
TI  - New antituberculosis drugs and concepts of prophylaxis.

PMID- 4362724
TI  - The enhancement by caffeine of alkylation-induced cell death, mutations and
      chromosomal aberrations in Chinese hamster cells, as a result of inhibition of
      post-replication DNA repair.

PMID- 4362725
TI  - Translation of collagen mRNA from chick embryo calvaria in a cell-free system
      derived from Krebs II ascites cells.

PMID- 4362726
TI  - [Subungual glomus tumors].

PMID- 4362727
TI  - Effect of exogenous conjugated estrogen on plasma gonadotropins and ovarian
      steroids during the menstrual cycle.

PMID- 4362729
TI  - Demonstration of a defect in the formation of adenosine 3',5'-monophosphate in
      vasopressin-resistant diabetes insipidus.

PMID- 4362728
TI  - Fertility control by intrauterine release of progesterone.

PMID- 4362730
TI  - Adenylate cyclase activity in immature rabbit lung.

PMID- 4362731
TI  - Treatment of precocious puberty with cyproterone acetate.

PMID- 4362732
TI  - Etiologic and epidemiologic investigations on the incidence of viral infections
      in two children communities during the period 1970-1971.

PMID- 4362734
TI  - [The effect of the adrenal cortex in bronchial asthma].

PMID- 4362733
TI  - Interferon production by lymphocytes in human milk.

PMID- 4362735
TI  - [Action of certain hormones (sex hormones, ACTH) on the cerebral circulation and
      mental processes].

PMID- 4362736
TI  - A simple fluorimetric microassay for adenine compounds in platelets and plasma
      and its application to studies on the platelet release reaction.
AB  - 1. The formation of a stable fluorescent product between chloroacetaldehyde and
      adenine or its derivatives provides the basis of a rapid simple assay for total
      adenine compounds in blood platelets and in plasma. The assay will measure down
      to 200pmol of adenine nucleotides. An evaluation of the method established the
      optimum conditions for the production of maximum fluorescence. 2. Values obtained
      for total adenine compounds in platelets were 12.9nmol/10(8) cells in man and
      7.8nmol/10(8) cells in rat. These closely agree with previous values for total
      platelet adenine nucleotides found by using a firefly luciferase assay, or a
      recycled NAD-linked photometric assay. This supports the concept that the
      chloroacetaldehyde reaction measures total adenine nucleotides in platelets. 3.
      Platelet aggregation induced by collagen was studied photometrically in 0.1ml
      volumes of citrated platelet-rich plasma, and total adenine nucleotides were
      assayed in platelets and plasma before and after aggregation. During aggregation
      58% of adenine nucleotides were released from human platelets, and 36% from rat
      platelets. 4. The chloroacetaldehyde assay is no substitute for more
      sophisticated procedures, but is a simple sensitive means of monitoring the
      release of adenine nucleotides from blood platelets and is particularly valuable
      when small plasma samples must be used.

PMID- 4362737
TI  - The detection and characterization by electron-paramagnetic-resonance
      spectroscopy of iron-sulphur proteins and other electron-transport components in
      chromatophores from the purple bacterium Chromatium.
AB  - Low-temperature e.p.r. (electron-paramagnetic-resonance) spectroscopy was used to
      detect electron-transport components in Chromatium chromatophores with e.p.r.
      signals in the g=2.00 region. High-potential iron protein (E(m8.0)=+325mV, where
      E(m8.0) is the midpoint potential at pH8) and a second component (g=1.90,
      E(m8.0)=+285mV) are oxidized in illuminated chromatophores. Two iron-sulphur
      proteins (g=1.94) with E(m8.0)=-290mV and E(m8.0)=-50mV are present. One
      (E(m8.0)=-50mV) is reduced on illumination. A component (g=1.82) with E(m8.0)=
      135mV is photoreduced at 10 degrees K. The midpoint potential of this component
      is altered by o-phenanthroline and pH. The properties of this component suggest
      that it is the primary electron acceptor of a photochemical system. Another
      component (g=1.98) also has some of the properties of a primary electron
      acceptor, but its function cannot be completely defined. These results show that
      iron-sulphur proteins are present in the electron-transport system of Chromatium
      and indicate their role in electron transport.

PMID- 4362738
TI  - Fate of corticotrophins in an isolated adrenal-cell bioassay and decrease of
      peptide breakdown by cell purification.
AB  - 1. The fate of corticotrophins in a trypsin-dispersed rat adrenal-cell assay
      system was investigated with a view to establishing whether differences in the
      rate of inactivation might contribute to potency differences observed between
      analogues. 2. Corticotrophin-(1-24)-tetracosapeptide and to a lesser extent
      synthetic 1-39 corticotrophins were found to be inactivated during incubation
      with cell suspension. 3. Peptide fragments were isolated by using
      [[(3)H(2)]Tyr(23)]corticotrophin-(1-24)- tetracosapeptide as a marker. The
      fragments indicate a peptidase with a predominantly tryptic specificity. 4. The
      peptidase is present in the extracellular fluid and is released from cells when
      they are damaged. 5. Cells were fractionated on an albumin gradient. Cells from
      the zona fasciculata and the zona intermedia or reticularis were present in
      fractions which produced fluorogenic steroids in response to corticotrophin. 6.
      Purification of the cells by centrifugation through albumin decreased degradation
      by peptidases, so that if the assay is carried out with a dilute suspension of
      purified cells peptide breakdown should not affect the observed potencies of
      adrenocorticotrophin analogues. 7. No binding of [[(3)H(2)]Tyr(23)]corticotrophin
      (1-24)- tetracosapeptide to cells could be detected at low concentrations of the
      peptide. This indicated that less than 120 receptors/cell are occupied during
      stimulation by a dose that would elicit approx. 80% of the maximal response.

PMID- 4362739
TI  - A protein kinase inhibitor in brown adipose tissue of developing rats.
AB  - A heat-stable protein was extracted from brown adipose tissue of infant rats that
      inhibited both purified bovine heart protein kinase and a crude preparation of
      protein kinase from brown fat. It did not act as an adenosine triphosphatase nor
      did it exert its effect by proteolytic action. Inhibition of protein kinase was
      affected in both the presence and the absence of cyclic AMP. Most of the
      inhibitory activity was present in the 100000g supernatant fraction of tissue
      homogenates. Inhibitory activity was highest perinatally and it declined 10 days
      after birth. It is suggested that the protein kinase inhibitor may play a role in
      regulating cyclic AMP actions.

PMID- 4362740
TI  - The development of cytochromes during the cell cycle of a glucose-repressed
      fission yeast, Schizosaccharomyces pombe 972h-.
AB  - 1. Spectrophotometric analysis of intact cells of Schizosaccharomyces pombe,
      harvested from exponentially growing cultures during the phase of glucose
      repression, revealed the presence of cytochromes a+a(3), c and at least two
      species of cytochrome b. 2. An absorption maximum at 554nm at 77 degrees K,
      previously attributed to cytochrome c(1), has been identified as a b-type
      cytochrome. 3. CO-difference spectra reveal the presence of cytochromes P-420 and
      P-450 in addition to cytochrome a(3). 4. The cell cycle was analysed by
      separation of cells into classes representing successive stages in the cell cycle
      by isopycnic zonal centrifugation. 5. Cytochromes c(548), b(554) and b(560) each
      exhibited a single broad maximum of synthesis during the cell cycle. 6. Amounts
      of cytochromes a+a(3) and b(563) (tentatively identified as cytochrome b(T) by
      its reaction on pulsing anaerobic cell suspensions with O(2)) oscillated in
      phase, and showed two maxima during the cycle; the second maximum of cytochromes
      a+a(3) was coincident with a maximum of activity of enzymically active cytochrome
      c oxidase. 7. The amount of cytochrome P-420 decreased during the first three
      quarters of the cell-cycle, whereas that of cytochrome P-450 increased during
      this period. 8. The discrepancy between spectrophotometric and enzymic assay of
      cytochrome c oxidase, the changing ratio of cytochrome a(3)/cytochrome a and the
      relationship between changes in cellular content of cytochromes and previous
      observations on respiratory oscillations during the cell cycle are discussed.

PMID- 4362741
TI  - Oxidative decarboxylation of glycollate and glyoxylate by leaf peroxisomes.
AB  - 1. The conditions under which peroxisomal preparations from leaves of spinach
      beet and spinach catalyse the release of (14)CO(2) from [1-(14)C]glycollate and
      [1-(14)C]glyoxylate were investigated. 2. At pH8, (14)CO(2) production from [1
      (14)C]glyoxylate was accompanied by equivalent quantities of formate. The
      accumulation of oxalate and the effects of various reagents, especially catalase
      inhibitors, show that glyoxylate is non-enzymically oxidized by H(2)O(2), which
      is generated by the oxidation of glyoxylate to oxalate by the action of
      glycollate oxidase. 3. (14)CO(2) is shown to be generated from [1
      (14)C]glycollate at pH8 by a similar reaction, but the H(2)O(2) is generated
      mainly by the oxidation of glycollate to glyoxylate. 4. The physiological
      significance of these reactions is discussed, with special reference to their
      role in photorespiration.

PMID- 4362742
TI  - Accumulation of lanthanum by rat liver mitochondria.
AB  - The interaction of La(3+) with rat liver mitochondria was examined with a wide
      variety of techniques permitting measurement of respiratory and structural
      responses. It is concluded that La(3+) is accumulated by mitochondria in a
      process that is at least partially energy-dependent, and is bound with quite high
      affinity to membrane-associated sites both external and internal to the inner
      membrane. The relative insensitivity of the accumulation process to respiratory
      inhibitors and to the permeant anion acetate has interesting implications for the
      mechanism of active cation transport.

PMID- 4362743
TI  - Microbial metabolism of amino alcohols. Aminoacetone metabolism via 1-aminopropan
      2-ol in Pseudomonas sp. N.C.I.B. 8858.
AB  - 1. Pseudomonas sp. N.C.I.B. 8858 grew well on d- and l-1-aminopropan-2-ol and on
      aminoacetone. 2. Cell-free extracts possessed high activities of inducibly formed
      l-1-aminopropan-2-ol-NAD(+) oxidoreductase, amino alcohol-ATP phosphotransferase,
      dl-1-aminopropan-2-ol O-phosphate phospho-lyase and aldehyde-NAD(+)
      oxidoreductase, but no 1-aminopropan-2-ol racemase or d-1-aminopropan-2-ol-NAD(+)
      oxidoreductase. 3. The amino alcohol kinase (activated by ADP) was non
      stereospecific towards 1-aminopropan-2-ol and was one-third as active with
      ethanolamine. The phospho-lyase was active with l- and d-1-aminopropan-2-ol O
      phosphate, but ethanolamine O-phosphate was only one-tenth as active as its
      higher homologues. The purified aldehyde dehydrogenase was active with
      propionaldehyde, acetaldehyde and also with methylglyoxal. The previously
      observed 2-oxo aldehyde dehydrogenase activity was considered to be due to the
      broadly specific aldehyde dehydrogenase. 4. Mutants of Pseudomonas sp. N.C.I.B.
      8858 deficient in 1-aminopropan-2-ol kinase, 1-aminopropan-2-ol O-phosphate
      phospho-lyase, aldehyde dehydrogenase or an enzyme involved in propionate
      metabolism were incapable of growth on aminoacetone or 1-aminopropan-2-ol as
      carbon source, although all except the kinase- or phospho-lyasedeficient mutants
      could use these compounds and ethanolamine as nitrogen sources. The aldehyde
      dehydrogenase-deficient mutants produced copious amounts of propionaldehyde and
      acetaldehyde during growth on the corresponding amino alcohols. 5. The path of
      aminoacetone metabolism in Pseudomonas sp. N.C.I.B. 8858 was concluded to involve
      l-1-aminopropan-2-ol, the O-phosphate ester of this compound, propionaldehyde and
      propionate as obligatory intermediates. d-1-Aminopropan-2-ol was metabolized by
      the same route as the l-isomer, gratuitously inducing formation of the
      stereospecific l-1-aminopropan-2-ol dehydrogenase. 6. Extracts of the pseudomonad
      grown with ethanolamine as the nitrogen source were devoid of 1-aminopropan-2-ol
      dehydrogenase, the kinase and the phospho-lyase, but exhibited cobamide coenzyme
      dependent deaminase activity. Mutants deficient in kinase or phospho-lyase
      (deaminating) grew well on ethanolamine as the nitrogen source. Ethanolamine
      deaminase was inactive with, but inhibited by, 1-aminopropan-2-ol.

PMID- 4362744
TI  - The involvement of endogenous dolichol in the formation of lipid-linked
      precursors of glycoprotein in rat liver.
AB  - Endogenous dolichol was shown to function as a natural acceptor of mannose
      residues by using regenerating rat liver containing [(3)H]dolichol. When
      subcellular fractions from this liver were incubated with GDP-[(14)C]mannose a
      double-labelled lipid, which represented 30% of the total [(14)C]mannolipid,
      could be isolated. This lipid was shown to be identical with the dolichol
      phosphate mannose formed from exogenous dolichol phosphate, by chromatography,
      stability to alkali and by chemical cleavage to mannose and dolichol derivatives.
      It was formed by the rough endoplasmic reticulum and mitochondria. If it is
      concerned in glycoprotein synthesis this would suggest that it functions in the
      formation of both secreted and mitochondrial glycoproteins. When both the
      dolichol and retinol of rat tissue were radioactive they made similar
      contributions to the synthesis of the lipid by liver microsomal fractions and
      intestinal epithelial cells.

PMID- 4362745
TI  - Rat brain microsomal gangliosides. Accessibility to a neuraminidase preparation
      and the possible existence of different pools in relation to their biosynthesis.
AB  - 1. Treatment of rat brain microsomal membranes with a neuraminidase preparation
      from Clostridium perfringens resulted in an almost complete conversion of
      polysialogangliosides into monosialogangliosides. 2. Neuraminidase treatment of
      the membranes did not increase the incorporation of N-[(3)H]acetylneuraminic acid
      from CMP-N-[(3)H]acetylneuraminic acid into the gangliosidic fraction, indicating
      that a monosialoganglioside is an acceptor of N-acetylneuraminic acid in these
      membranes only if, in addition to having the right chemical structure, it is in a
      proper position, probably in relation to the endogenous sialyltransferases. 3.
      These experiments also indicated that no independent turnover of the
      neuraminidase-labile N-acetylneuraminyl groups of gangliosides occurred in vitro.
      4. N-[(3)H]Acetylneuraminic acid from endogenous polysialogangliosides labelled
      in vitro was released by neuraminidase at a slower rate than N-acetylneuraminic
      acid from unlabelled gangliosides of the same membranes. From this it was
      concluded that recently synthesized polysialogangliosides (completed in vitro)
      are in the membranes in a position less accessible to neuraminidase than are
      those synthesized earlier which were present in the membranes at the start of the
      labelling experiment.

PMID- 4362747
TI  - Effect of phenobarbital or pregnenolone-16alpha-carbonitrile (PCN) pretreatment
      on acute carbon tetrachloride hepatotoxicity in rats.

PMID- 4362746
TI  - Effects of collagen and of aspirin on the concentration of guanosine 3':5'-cyclic
      monophosphate in human blood platelets: measurement by a prelabelling technique.
AB  - A method is described for isolating cyclic [(3)H]GMP from platelets preincubated
      with [(3)H]guanine. Collagen increased and aspirin decreased the cyclic [(3)H]GMP
      concentration in platelets. The results are consistent with a role for cyclic GMP
      in the platelet release reaction.

PMID- 4362748
TI  - Triethylcholine inhibition of phosphatidylcholine synthesis in synaptosomes and
      mouse leukemic cells L1210 and accelerated synaptosomal uptake of choline and
      triethylcholine in the presence of acetylcholine.

PMID- 4362749
TI  - Purification of human renin and inhibition of its activity by pepstatin.

PMID- 4362750
TI  - Effect of certain metabolic regulators on the activity of lysosomal enzymes in
      regenerating rat liver.

PMID- 4362751
TI  - [New histochemical technic for phospholipid determination].

PMID- 4362752
TI  - [Study of the mechanism of inhibition of horse liver alcohol dehydrogenase by 3,
      5, 3'-triiodo-L-thyronine and its formic, acetic and propionic analogues].

PMID- 4362753
TI  - [Sensitizing action of metabolic inhibitors on the responses of isolated guinea
      pig ileum to the effects of acetylcholine, histamine, angiotensin and
      bradykinin].

PMID- 4362754
TI  - Mesophilic clostridia in Puget Sound.

PMID- 4362756
TI  - Production and control of extracellular enzymes in Micrococcus sodonensis.

PMID- 4362755
TI  - Stability of different viruses in a newly developed transport medium.

PMID- 4362757
TI  - Purification and partial characterization of an antibiotic produced by Myxococcus
      xanthus.

PMID- 4362758
TI  - Characterization of the nadR locus in Escherichia coli.

PMID- 4362759
TI  - Interaction of phentolamine and noradrenaline on myocardial contractility and
      adenyl cyclase activity.

PMID- 4362760
TI  - [Abnormal serum lipoproteins in cholestatic viral hepatitis (author's transl)].

PMID- 4362761
TI  - [Case of malabsorption syndrome, "Meiteisho" (endogenous ethanol intoxication)
      and polyneuropathy].

PMID- 4362762
TI  - Ultrastructural changes associated with UV irradiation in the "germinal plasm" of
      Xenopus laevis.

PMID- 4362763
TI  - Some aspects of the behavior of young and adult rats treated with p
      chlorophenylalanine in infancy.

PMID- 4362764
TI  - Formation of lithogenic bile in man.

PMID- 4362765
TI  - Murine reticulum cell neoplasms type B (Hodgkin's-like lesions) induced in BALB-c
      mice with field isolates of murine leukemia virus.

PMID- 4362767
TI  - Letter: Serum dopamine-beta-hydroxylase activity in patients with leukemia and in
      patients with hepatoma.

PMID- 4362766
TI  - Acceptor control ratio of mitochondria. Factors affecting it in Morris hepatoma
      5123 and Yoshida hepatoma AH-130.

PMID- 4362768
TI  - [Polysynaptic reactions and internuncial neurons of the red nucleus].

PMID- 4362769
TI  - Conjugation of enzymes to anti-poliovirus globulin: effect of enzyme molecular
      weight on virus neutralization capacity.

PMID- 4362770
TI  - The enhanced immogenicity of horse cytochrome C by light dinitrophenylation.

PMID- 4362771
TI  - Retention of significant antibody binding by surface antigens of feline leukemia
      cells (FLA) after fixation with formaldehyde and glutaraldehyde.

PMID- 4362773
TI  - Cytomegalovirus interference in vitro.
AB  - Cytomegalovirus (CMV) was shown to induce a state of viral interference in human
      embryo fibroblast cultures (HEF). This interference was characterized by: (i)
      requirement for infectious virus; (ii) a latent period (48 to 96 h) for
      establishment of the interference; (iii) activity against a representative group
      of heterologous viruses; (iv) loss of interfering activity when challenged with a
      high multiplicity of infection; (v) lack of effect on adsorption of virus; (vi)
      mediation by a soluble product of CMV-cell interaction that it is not blocked by
      anti-CMV antibody; and (vii) absence of detectable interferon, although the
      soluble mediator shares a number of characteristics with interferon. This state
      of interference in HEF cultures could be simulated by extended exposure to
      subdetectable levels of human interferon. It is postulated that CMV induced the
      production of a soluble, interferon-like mediator of viral interference and that
      continuous exposure of the HEF culture to this mediator resulted in the
      development of resistance to a number of heterologous viruses.

PMID- 4362772
TI  - Control of interferon, migration inhibition factor, and expression of virus
      capsid antigens in Burkitt's lymphoma-derived cell lines: role of L-arginine.
AB  - The effects of an arginine-utilizing mycoplasma, Mycoplasma arginini, and of
      varying levels of arginine in the growth media of the Epstein-Barr virus (EBV)
      containing EB1 and EB3 cell lines, and the EBV-free RPMI 1788 cell line, were
      studied. l-Arginine, at a concentration of 0.1 mM in the growth medium, led to a
      reduction of the EBV capsid antigen content of the EB1 and EB3 cells lines as
      determined by indirect immunofluorescence, and M. arginini infection enhanced
      this reduction. The synthesis of two immune products, interferon and macrophage
      migration inhibition factor, was enhanced by growing the cell lines in medium
      containing arginine at a concentration of 0.1 mM, but the RPMI 1788 cell line
      produced much less of both products than EB1 or EB3 under these conditions.
      Infection of the cell lines with M. arginini reduced the amount of interferon
      produced and completely inhibited macrophage migration inhibition factor
      synthesis. The addition of arginine to a final concentration of 0.6 mM in the
      growth medium caused a dual effect: the EB1 and EB3 cell lines maintained the
      original level of EBV capsid antigens, even when infected with M. arginini;
      immune product synthesis was greatly reduced or completely inhibited by the
      addition of arginine, and M. arginini infection caused no further reduction of
      immune product synthesis.

PMID- 4362774
TI  - A new method for the investigation of the capture reaction in phosphatase
      cytochemistry. 3. Effects of the composition of the incubation medium on the
      trapping of phosphate ions in a model system.

PMID- 4362775
TI  - Alleged rape. An invitational symposium.

PMID- 4362776
TI  - Analogs of cyclic AMP and cyclic GMP: general methods of synthesis and the
      relationship of structure to enzymic activity.

PMID- 4362777
TI  - The neuroendocrinology of human sleep.

PMID- 4362778
TI  - Effects of ethanol on gastric mucosal adenosine 3', 5' monophosphate (cAMP).

PMID- 4362780
TI  - [Coronary diseases and economic development. Apropos of 45 cases in black
      Africans].

PMID- 4362781
TI  - [Current concepts on the physiology of pain at the spinal cord level.
      Neurosurgical applications].

PMID- 4362779
TI  - Protein and polypeptide hormones as inhibitors.

PMID- 4362782
TI  - [Letter: Non-specific immunostimulation of Australia antigen serum level].

PMID- 4362783
TI  - [Exploration of thymus function in man. 1. Demonstration of a circulating thymic
      hormone].

PMID- 4362784
TI  - The Montefiore Hospital after-care program.

PMID- 4362785
TI  - Isoniazid as a cause of neuropathy and sideroblastic anaemia.

PMID- 4362787
TI  - Triglyceride storage disease. A group of inborn errors of triglyceride
      metabolism.

PMID- 4362786
TI  - Familial lipoatrophic diabetes with dominant transmission. A new syndrome.

PMID- 4362788
TI  - [Krukenberg's tumor. Review apropos of 2 cases].

PMID- 4362789
TI  - Reconstruction of the trachea. Experience in 100 consecutive cases.

PMID- 4362790
TI  - Occurrence of precipitating antibodies to bluetongue virus in sera of farm
      animals in Iran.

PMID- 4362791
TI  - [Anisotropic substances in the lymph nodes in sarcoidosis (author's transl)].

PMID- 4362792
TI  - [Study of the phospholipid makeup of human stroma and erythrocytes].

PMID- 4362794
TI  - [Cytochromes of the plague microbe].

PMID- 4362793
TI  - [Biochemical evaluation of the viability of an amputated extremity before
      transplantation].

PMID- 4362796
TI  - [Neuraminidase in the cells and toxins of Cl. perfringens].

PMID- 4362795
TI  - [Disorder of oxidative phosphorylation in rabbit liver mitochondria during the
      development of terminal states].

PMID- 4362797
TI  - [Interrelationship of the fat-mobilizing and hypocalcemic effects of some
      hypophyseal hormones and adiposine].

PMID- 4362798
TI  - [Possibilities of analytical determination of food irradiation].

PMID- 4362799
TI  - [On the biochemical mechanisms of the heart automaticity. Study on myxine
      (authors transl)].

PMID- 4362800
TI  - Homozygous familial hypercholesterolemia: specificity of the biochemical defect
      in cultured cells and feasibility of prenatal detection.

PMID- 4362801
TI  - Gene frequencies of erythrocytic enzymes of Alaskan Eskimos and Athabaskan
      Indians.

PMID- 4362802
TI  - Neurogenic pressor response due to mesencephalic electrical stimulation--effect
      of blockade of renin-angiotensin system.

PMID- 4362803
TI  - Effects of dibutyryl cyclic AMP on alpha-methyl-d-glucoside accumulation in
      rabbit kidney.

PMID- 4362804
TI  - Initiation of transcription by RNA polymerases of Escherichia coli and phage T3.

PMID- 4362806
TI  - Termination and antitermination in transcription: control of gene expression.

PMID- 4362805
TI  - Studies on the transcription of simian virus 40 and adenovirus type 2.

PMID- 4362807
TI  - Control of transcription in Bacillus brevis by small molecules.

PMID- 4362809
TI  - [Editorial: Role of vasomotricity in the regulation of pancreatic exocrine
      secretion].

PMID- 4362808
TI  - Transcription of double-stranded viral and cellular DNAs by purified mammalian
      DNA-dependent RNA polymerases.

PMID- 4362810
TI  - (3H)-adenosine nucleotide and (3H)-noradrenaline uptake by cold stored guinea-pig
      taenia caecum; mechanical effects and release of (3H)-adenosine nucleotide by
      noradrenaline, papaverine, and nitroglycerine.
AB  - 1. Cold storage (2 degrees C) treatment progressively reduced noradrenaline
      uptake by the taenia caecum of the guinea-pig. After 15 days of cold treatment,
      [(3)H]-noradrenaline uptake by tissue was reduced to about 10% of control. On the
      other hand, prolonged cold storage failed to decrease [(3)H]-adenosine uptake by
      the taenia caecum.2. Cocaine (10 muM) inhibited noradrenaline uptake by about 82%
      but nucleoside uptake was inhibited by 20%. Cocaine treatment failed to decrease
      the residual noradrenaline uptake in the cold stored strips (more than 10 days).
      Phenoxybenzamine (1 muM) or oligomycin (1 mug/ml) treatment decreased the tissue
      adenosine uptake to about 34% and 28% of the respective controls.3. Based on thin
      layer chromatography, it was estimated that approximately 68% of [(3)H]-adenosine
      was converted into and retained as [(3)H]-ATP in the fresh tissues, a small
      fraction was accountable as [(3)H]-adenosine (18%) but virtually no [(3)H]-AMP,
      [(3)H]-cyclic AMP or [(3)H]-ADP was detected. Similar distribution of
      radioactivity of nucleotides was observed in tissues cold stored for 8 days.4.
      The inhibition of the mechanical activity of taenia by noradrenaline (10 muM),
      papaverine (100 muM) and nitroglycerine (100 muM) was accompanied by [(3)H]
      adenine nucleotide but not [(3)H]-noradrenaline release. Treatment with
      phentolamine and propranolol (both 1 muM) had no effect on the adenine nucleotide
      release elicited by nicotine and electrical field stimulation, whereas such
      treatment reduced the inhibitory action of both stimuli.5. These results suggest
      that the nucleotide release after application of electrical and chemical
      stimulation may be from an extraneurogenic source. Thus, we conclude that ATP or
      a related nucleotide is not the chemical transmitter of the non-adrenergic
      inhibition in the taenia caecum of the guinea-pig.

PMID- 4362811
TI  - Picrotoxin antagonism of gamma-aminobutyric acid inhibitory responses and
      synaptic inhibition in the rat substantia nigra.
AB  - Neurones in the substantia nigra of the rat, anaesthetized with urethane, are
      inhibited both by electrical stimulation of the ipsilateral caudate nucleus and
      by iontophoretically applied gamma-aminobutyric acid (GABA). Iontophoretically
      applied picrotoxin reversibly blocks both of these inhibitory responses. These
      results are consistent with the hypothesis that GABA is the transmitter released
      by the inhibitory striato-nigral pathway.

PMID- 4362812
TI  - Study on the propagation of Herpes simplex virus (type 2) into the brain after
      intraocular injection.

PMID- 4362813
TI  - Brain stem-thalamus reciprocal influences in the cat.

PMID- 4362815
TI  - Three modes of repetitive firing and the role of threshold time course between
      spikes.

PMID- 4362814
TI  - [Genetic factors as determinants of the waking-sleep cycle in the mouse (author's
      transl)].

PMID- 4362816
TI  - A frequency shift in the hippocampal theta activity: an electrical correlate of
      central action of ACTH analogues in the dog?

PMID- 4362817
TI  - [Research on physiological factors of reproduction in ovoviparous fishes.
      Experimental analysis in Gambusia sp].

PMID- 4362819
TI  - Letter: Narcolepsy.

PMID- 4362818
TI  - Influence of dichloromethylene diphosphonate (Cl2MDP) and calcitonin on bone
      resorption, lactate production and phosphatase and pyrophosphatase content of
      mouse calvaria treated with parathyroid hormone in vitro.

PMID- 4362821
TI  - [Mathematical model of receptive relaxation].

PMID- 4362820
TI  - Arteriography in tumors of the orbit.

PMID- 4362822
TI  - Transjugular liver biopsy and cholangiography.

PMID- 4362823
TI  - [Standardized bilateral pelvic phlebography with pressure determination].

PMID- 4362824
TI  - [Acute ilio-femoral vein thrombosis (author's transl)].

PMID- 4362825
TI  - [The radiological anatomy and pathology of the veins of the forearm (author's
      transl)].

PMID- 4362827
TI  - [Lipiodol emboli, lipodiarese and pulmonary capillaries (author's transl)].

PMID- 4362826
TI  - [Selective spinal angiography and its use in the diagnosis of spinal angiomas
      (author's transl)].

PMID- 4362828
TI  - [A contribution to "exogenous, allergic alveolitis" (author's transl)].

PMID- 4362829
TI  - [Idiopathic pulmonary haemosiderosis (author's transl)].

PMID- 4362830
TI  - [Idiopathic fibrosing mediastinitis (author's transl)].

PMID- 4362832
TI  - [A new dilution method for the investigation of the pulmonary circulation and the
      relationship between pulmonary and bronchial arteries (author's transl)].

PMID- 4362831
TI  - [Powdered contrast medium for bronchography. Animal experiments using tantulum,
      tungsten and Hytrast (author's transl)].

PMID- 4362833
TI  - [Unilateral and regional determination of residual volume of the lung using
      133xenon. Acomparison with a global gas dilution method (helium) (author's
      transl)].

PMID- 4362834
TI  - [Isotope functional diagnosis of the parotid. II. The abnormal parotid (author's
      transl)].

PMID- 4362835
TI  - [Contrast media extravasation following skull injuries].

PMID- 4362836
TI  - [Norm variations of the sella turcica: large, free, middle-clinoid processes].

PMID- 4362837
TI  - [Vascular changes of the gastric fornix following surgical interventions at the
      pancreas].

PMID- 4362838
TI  - [Psoriatic osteopathy without arthritis].

PMID- 4362839
TI  - [Suture granulomas as a cause of postcholecystectomy syndrome].

PMID- 4362840
TI  - [Trichobezoars of the stomach].

PMID- 4362841
TI  - The determination of age of yearling beef cattle at post-mortem by subjective
      appraisals of bone and muscle development.

PMID- 4362842
TI  - Characterization of enzyme and metabolic patterns in mice selected for rapid post
      weaning growth rate.

PMID- 4362843
TI  - Developmental aspects of glucose and VFA metabolism in the germfree and
      conventional ruminant.

PMID- 4362844
TI  - Effect of angiotensin II on aldosterone secretion in the conscious rat.

PMID- 4362845
TI  - Factors influencing the uptake of (alpha-14C)aminoisobutyric acid by rat testes.

PMID- 4362846
TI  - Prolactin receptors: characteristics of the particulate fraction binding
      activity.

PMID- 4362847
TI  - [Reccurent facial paralysis in a child. Vascular tumor of the cavum tympani].

PMID- 4362848
TI  - Inhibition of cartilage macromolecular synthesis by prostaglandin A.

PMID- 4362849
TI  - Concomitant association between high plasma levels of growth hormone and low
      hepatic mixed-function oxidase activity in the young rat.

PMID- 4362851
TI  - The psychiatric nurse as the guardian of the ward atmosphere.

PMID- 4362850
TI  - A strategy to improve patient-staff interaction in a mental health facility.

PMID- 4362852
TI  - Nurse, I need help; the school nurse's role in suicide prevention.

PMID- 4362853
TI  - Conflict within the marital dyad.

PMID- 4362854
TI  - The Barrie day care service; a study in partial hospitalization in a general
      hospital psychiatric facility.

PMID- 4362855
TI  - Mental health--what is it?

PMID- 4362857
TI  - Speaking out on: when is being generous something else?

PMID- 4362856
TI  - The successful management of "refractory" ambulatory schizophrenic patients.

PMID- 4362858
TI  - Drugs and trends; the "unproven" "proven" drug.

PMID- 4362859
TI  - Geriatrics; statistics on the population and characteristics of the elderly in
      the United States.

PMID- 4362860
TI  - Anthropology, nursing and mental health.

PMID- 4362861
TI  - Effects of L-glutamine deprivation on growth of HVJ (Sendai virus) in BHK cells.
AB  - l-Glutamine requirement for viral maturation was found in BHK-HVJ cells, a cell
      line of baby hamster kidney cells persistently infected with HVJ (Sendai virus).
      Synthesis of envelope protein in BHK-HVJ cells was markedly suppressed by
      deprivation of l-glutamine, whereas development of nucleocapsid (S) antigen was
      less affected. More detailed examination of this phenomenon was carried out by
      using a cytolytic system. Growth of HVJ in BHK cells cultured in media deprived
      of various amino acids was investigated, and omission of l-glutamine from culture
      medium resulted in a marked inhibitory effect on the release of infectious virus
      and synthesis of envelope protein, although synthesis of virus-specific RNA and
      nucleocapsid antigen in the cells was readily detected. When l-glutamine was
      restored to the culture medium, infectious virus and envelope protein could be
      detected. l-Glutamic acid, l-aspartic acid, or l-alanine could be substituted for
      l-glutamine. Effects of l-glutamine deprivation on HVJ growth in several other
      cells were also investigated. The growth of HVJ in the cells other than BHK and
      FL cells was not suppressed by lack of l-glutamine. Growth of Sindbis virus in
      BHK cells was also markedly retarded in the absence of l-glutamine.

PMID- 4362862
TI  - Polyoma viral DNA replicated as a nucleoprotein complex in close association with
      the host cell chromatin.
AB  - Polyoma viral DNA is shown to be replicated in close association with the mouse
      cell chromatin. Two virus-specific nucleoprotein complexes, designated complex A
      and B, can be dissociated from the isolated chromatin by gentle homogenization in
      0.5 M NaCl. Complex A contains only replicating polyoma (Py) DNA whereas complex
      B contains only mature Py DNA I. The results show, furthermore, that complex A,
      containing viral DNA in different stages of replication, and complex B are both
      nucleoproteins with the same buoyant density. The data presently available
      suggest that newly synthesized stretches of Py DNA are immediately complexed with
      mouse cell histones and that complex B becomes the "core" of progeny Py virions.
      These results suggested that Py-induced replication of the mouse cell chromatin
      may be necessary to provide replicating Py DNA with histones.

PMID- 4362863
TI  - Translation of mRNA from simian virus 40-infected cells into simian virus 40
      capsid protein by cell-free extracts.
AB  - Messenger RNA was isolated from simian virus 40 (SV40)-infected and mock-infected
      cells by chromatography on poly(U) sepharose. When added to cell-free extracts
      from Chinese hamster ovary cells or rabbit reticulocytes, RNA from the infected
      cells, but not from mock-infected cells, stimulated synthesis of the major SV40
      capsid protein. Identification of this species was done by sodium dodecyl sulfate
      gel electrophoresis, peptide mapping, and immunoprecipitation. The in vitro
      synthesized capsid protein was slightly different from virion assembled capsid
      protein, as shown by separation upon chromatography on hydroxylapatite and by
      minor differences in the peptide map.

PMID- 4362864
TI  - Comparison of JC and BK human papovaviruses with simian virus 40: restriction
      endonuclease digestion and gel electrophoresis of resultant fragments.
AB  - JC virus was found to have a buoyant density of 1.20 g/cm(3) in linear sucrose
      D(2)O and 1.35 g/cm(3) in cesium chloride isopycnic gradients. DNA extracted
      either from JC-infected cultures or from gradient-purified virions occupied a
      dense position relative to linear DNA in cesium chloride/ethidium bromide
      gradients, and the circular configuration of the extracted DNA was confirmed by
      electron microscopy, with a measured molecular weight of 2.93 x 10(6). DNA from
      BK virus was similarly prepared and compared to JC and to an SV40 DNA standard by
      digestion with restriction endonuclease preparations from Haemophilus influenzae,
      Haemophilus parainfluenzae, and Escherichia coli. Digests were
      electrophoretically analyzed on gradient polyacrylamide slab gels or agarose
      gels, and the three viruses were found to have distinctly different cleavage
      patterns by this form of analysis: JC and BK viruses were almost entirely
      different from SV40 and significantly different from each other. Thus, JC and BK
      human papovaviruses appear to be discrete new members of the papovavirus group,
      rather than SV40 variants.

PMID- 4362865
TI  - Establishment and maintenance of the interferon-induced antiviral state: studies
      in enucleated cells.
AB  - Requirements for the physical presence of the cell's nucleus for the
      establishment and maintenance of the interferon-induced antiviral state were
      investigated. Enucleated chicken embryo fibroblasts were obtained by cytochalasin
      B treatment during centrifugation. The inhibition of vaccinia virus cytoplasmic
      DNA synthesis, monitored by autoradiography, was used to measure the antiviral
      activity resulting from interferon treatment. The antiviral state is not
      established in cells treated with interferon after removal of their nuclei. On
      the other hand, cells first treated with interferon for 6 or 12 h and then
      enucleated express the antiviral state. Furthermore, the antiviral state is
      maintained in enucleated cells for 16 h after enucleation. The antiviral state
      appears to be more stable in enucleates than in the residual nucleated cells
      found in the same cultures. Single cells of antiviral populations are found to be
      either fully permissive or fully restrictive to vaccinia DNA synthesis. The
      effect of an increasing intracellular multiplicity of infectious virus is to
      overcome the antiviral cell's block against viral DNA synthesis.

PMID- 4362866
TI  - Human cytomegalovirus. II. Lack of relatedness to DNA of herpes simples I and II,
      Epstein-Barr virus, and nonhuman strains of cytomegalovirus.
AB  - The purified DNA of human cytomegalovirus, radiolabeled in vitro, was examined
      for homology to Epstein-Barr virus, herpes simplex type I and II, and simian and
      murine cytomegalovirus DNA by DNA-DNA reassociation kinetics analyses with the S1
      enzyme differential digestion technique. Cross-matching of the DNAs showed no
      relatedness or less than 5% detectable homology.

PMID- 4362867
TI  - RNA transcription by the virion polymerases of five rhabdoviruses.
AB  - The presence of a virion-associated RNA-dependent RNA polymerase in five
      serologically distinct rhabdovirus isolates (vesicular stomatitis virus [VSV]
      Indiana, VSV New Jersey, Cocal, Chandipura, and Piry viruses) has been
      demonstrated. The enzyme for each virus has been shown to be a transcriptase
      capable of synthesizing in vitro RNA which is complementary to the viral genome.
      By sequence analyses it has been shown that, for each rhabdovirus, transcription
      is multiply initiated with specific 5' nucleotide sequences. The results indicate
      that, for all five viruses, the initiation of transcription involves similar
      sequences (e.g., pppApCpGp..., pppGpCp..., and possibly one or two other
      sequences), suggesting relatedness and some genome conservation among these
      viruses.

PMID- 4362868
TI  - Antigenic phenotypes and complementation groups of temperature-sensitive mutants
      of simian virus 40.
AB  - The antigenic phenotypes of several temperature-sensitive mutants of simian virus
      40 were determined by an immunofluorescence microtechnique that allowed a very
      high degree of internal control for the conditions of virus infection and
      antigenic staining. The tumor (T), U, capsid protein (C), and virion (V) antigens
      were investigated. Productive infection in monkey cells and abortive infection in
      mouse cells were simultaneously monitored for antigen production at both
      permissive and restrictive temperatures. Complementation analyses of the mutants
      demonstrated two complementing groups (A and B) and one noncomplementing group
      ((*)). One of the complementing groups could be subdivided into two subgroups
      having very different antigenic phenotypes. The following phenotypes were
      observed at the restrictive temperature in monkey cells. (i) The noncomplementing
      group produced none of the antigens. (ii) Group A induced T antigen in moderately
      but consistently reduced numbers of cells. Other antigens were markedly reduced
      or absent. (iii) Some of the group B mutants produced T antigen but little or no
      U and V antigens. The C antigen appeared in the nucleolus and cytoplasm of this
      subgroup. (iv) In the other group B mutants, antigen synthesis was not altered.
      Similar phenotypes were observed in mouse cells, except that U, C, and V antigens
      could not be detected during either the mutant or wild-type virus infections at
      any temperature.

PMID- 4362869
TI  - Characterization of new regulatory mutants of bacteriophage T4.
AB  - Plating techniques which eliminate T4 plaque formation on Escherichia coli by
      folate analogue inhibition of dihydrofolate (FH(2)) reductase (EC 1.5.1.3)
      allowed the isolation of folate analogue-resistant (far) mutants of T4. One class
      of far mutants overproduces the phage-induced FH(2) reductase. Deoxycytidylate
      deaminase (EC 3.5.4.12), thymidine kinase (EC 2.7.1.21), and deoxycytidine
      triphosphatase (EC 3.6.1.12) are also overproduced by 20 min after infection at
      37 C. The overproduction of FH(2) reductase by these far mutants is not affected
      by the absence of DNA synthesis. Other types of mutations that affect the
      synthesis of early enzymes cause overproduction in the absence of DNA synthesis
      of some of the above enzymes but not of FH(2) reductase. Therefore, overproducing
      far mutants apparently have mutations in previously undescribed genes controlling
      the expression of the T4 genome. Three of four mutants under study map near gene
      56, and one maps near gene 52. All of these mutants show delays in DNA synthesis,
      phage production, and lysis and appear to show decreased levels of RNA synthesis
      based on the cumulative incorporation of uridine.

PMID- 4362870
TI  - Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. IX. Template
      topography in the early region of simian virus 40.
AB  - The DNAs of the five nondefective adenovirus 2 (Ad2)-simian virus 40 (SV40)
      hybrid viruses contain overlapping segments of the early region of wild-type SV40
      DNA. The complementary DNA strands of these five viruses have been separated with
      synthetic polyribonucleotides in isopycnic cesium chloride gradients. The
      relative amounts of early and late SV40 template in the DNA of each virus were
      determined by RNA-DNA hybridization with late lytic SV40 RNA, which contains
      sequences complementary to both templates. From the distribution of early and
      late templates in the five overlapping SV40 segments, we conclude that either the
      entire early region of SV40 is symmetrically transcribed in vivo, or, more
      probably, that the early SV40 templates are not contiguous.

PMID- 4362871
TI  - Gene expression during the development of bacteriophage phi 29. 3. Analysis of
      viral-specific protein synthesis with suppressible mutants.
AB  - Fifty-four suppressible mutants of bacteriophage phi29 have been isolated with a
      variety of mutagens and assigned to eight complementation groups. Viral-specific
      protein synthesis in UV light-irradiated, nonsuppressing Bacillus subtilis 60084
      was analyzed with exponential acrylamide gels. Four additional phi29 proteins
      which were undetected on ordinary acrylamide gels are reported in this paper.
      Five phage phi29 proteins have been unambiguously assigned to specific cistrons.
      Two cistrons had pleiotropic effects on viral protein synthesis. Mutants in
      cistrons I or II were unable to synthesize DNA in nonsuppressing bacteria.
      Mutants in cistron I were unable to attach viral chromosomes to the host cell
      membrane, and the protein responsible for this function has been identified. The
      other viral protein playing a role in phage phi29 DNA synthesis is also
      identified and assigned to cistron II. Mutants in cistron II can attach viral
      chromosomes to membrane, but cannot synthesize DNA in nonsuppressing bacteria.

PMID- 4362873
TI  - Fragmentation of RNA in virus particles of rhinovirus type 14.
AB  - Purified particles of rhinovirus type 14 lose infectivity during incubation at
      34.5 C as a result of fragmentation of RNA genomes within intact virions.

PMID- 4362874
TI  - Spontaneous toxoplasmosis in macaques: a report of four cases.

PMID- 4362872
TI  - Immunochemical procedure for partial purification of newly synthesized proteins
      in polyoma virus-infected mouse cells.
AB  - A broad-spectrum antiserum has been obtained against nuclear proteins from normal
      mouse fibroblasts. Solid phase immunoadsorbants prepared from the serum
      specifically bind the corresponding antigens. The removal in this way of a
      significant fraction of host proteins leads to partial purification of viral and
      virus-induced polypeptides from polyoma virus-infected cell extracts. Four main
      peptides can be selected, with respective molecular weights of 90,000, 70,000,
      46,000, and 41,000.

PMID- 4362876
TI  - Silvered leaf-monkeys (Presbytis cristatus). I. Colony management, caging, diet,
      and biologic values.

PMID- 4362875
TI  - Feline infectious peritonitis in a closed breeding colony.

PMID- 4362877
TI  - Silvered leaf-monkeys (Presbytis cristatus). II. Gastrointestinal parasites and
      their treatment.

PMID- 4362878
TI  - Colonization patterns of aerobic gram-negative bacteria in the cloaca of Rana
      pipiens.

PMID- 4362879
TI  - The effects of various levels of dietary fat and apple supplementation of growth
      of golden hamsters (Mesocricetus auratus).

PMID- 4362880
TI  - Comparative erythrocyte metabolism: studies using guinea pig cells.

PMID- 4362881
TI  - Tuberculous spondylitis and Pott's paraplegia in a rhesus monkey (Macaca
      mulatta).

PMID- 4362882
TI  - A technic for thymectomy in the adult rat.

PMID- 4362883
TI  - A technic for neonatal thymectomy in marmoset monkeys.

PMID- 4362884
TI  - Modification of the orbital sinus bleeding technic for rabbits.

PMID- 4362885
TI  - Hexamitiasis in laboratory mice, hamsters, and rats.

PMID- 4362886
TI  - A simple procedure for long-term intravenous infusion in the rat.

PMID- 4362887
TI  - An exteriorized cranial vena caval catheter for serial blood sample collection
      from miniature swine.

PMID- 4362888
TI  - A simple hydraulic manostat for use with volume-controlled respirators.

PMID- 4362889
TI  - A restraint device for electroejaculation of squirrel monkeys (Saimiri sciureus).

PMID- 4362891
TI  - Unilateral renal and urogenital tract aplasia in a guinea pig (Cavia porcellus).

PMID- 4362890
TI  - Carotid-jugular arteriovenous fistulas for chronic hemodialysis in dogs.

PMID- 4362892
TI  - A new date mating system for mice in timer-activated breeding cages.

PMID- 4362893
TI  - The opposum (Didelphis virginiana Kerr) as a biomedical model. I. Research
      perspective, husbandry, and laboratory technics.

PMID- 4362895
TI  - The opossum (Didelphis virginiana Kerr) as a biomedical model. 3. Breeding the
      opossum in captivity: methods.

PMID- 4362894
TI  - The opossum (Didelphis virginiana Kerr) as a biomedical model. II. Breeding the
      opossum in captivity: facility design.

PMID- 4362896
TI  - Letter: Effect of prolonged treatment of high doses of chorionic gonadotropin on
      immature male rats.

PMID- 4362897
TI  - Letter: Identification methods for rodents.

PMID- 4362898
TI  - [Late first appearance of porphyria in a patient with primary liver cancer].

PMID- 4362899
TI  - A study of nutritional status of preschool children in the United States, 1968
      1970.

PMID- 4362900
TI  - Neonatal screening for hyperlipidemia.

PMID- 4362901
TI  - Cholesterol at birth and age 1: comparison of normal and hypercholesterolemic
      neonates.

PMID- 4362902
TI  - [The functional state of the adrenal cortex in thyrotoxicosis patients at remote
      periods following conservative treatment and radioactive iodine therapy].

PMID- 4362903
TI  - [The effect of prolonged administration of ACTH on the functional activity of the
      hypothalamo-hypophyseo-adrenal cortex system].

PMID- 4362904
TI  - [The state of the adrenocorticotropic function of the hypophysis under various
      experimental influences].

PMID- 4362905
TI  - [Morphologic aspects of the problem of hypophyseal regulation of the glomerular
      zone of the adrenals. 3. The effect of ACTH on the cortical cells of a
      demedullated adrenal gland].

PMID- 4362906
TI  - [Characteristics of the cytoplasmic and nuclear receptors for estradiol in the
      rat uterus with different functional activity of the hypophyseo-gonadal system].

PMID- 4362907
TI  - Editorial: Current status of our knowledge about cyclic AMP.

PMID- 4362908
TI  - Stimulation at 50 pulses per second in the normal person: its implication in the
      differential diagnosis from myasthenia gravis and myasthenic syndrome.

PMID- 4362909
TI  - Bilateral adrenalectomy in selected patients with carcinoma of the breast.

PMID- 4362910
TI  - Synovial sarcoma in children.

PMID- 4362911
TI  - The clinical application of a specific radioimmunoassay for human chorionic
      gondotropin in trophoblastic and nontrophoblastic tumors.

PMID- 4362912
TI  - Neutralization of the hemodynamic effects of endotoxin by polymyxin B.

PMID- 4362913
TI  - Ultrastructural changes in the liver of equine fetuses aborted during
      rhinopneumonitis.

PMID- 4362914
TI  - Malignant fibrous histiocytoma of the vagina.

PMID- 4362915
TI  - Investigation of the release reaction in platelets exposed to phorbol myristate
      acetate.
AB  - Phorbol myristate acetate (PMA), the active principle of croton oil, is a potent
      platelet aggregating agent. Previous cytochemical and electron microscopic
      studies demonstrated that PMA caused selective labilization of platelet storage
      granules resulting in their conversion to distended vacuoles. Communication was
      established between the enlarged, almost empty vacuoles and the surrounding
      plasma through channels of the open canalicular system. The present study has
      explored the possibility that the effect of PMA on platelet storage organelles
      stimulates a process of secretion. Analysis of the release reaction in platelets
      after exposure to PMA revealed that significant amounts of serotonin and adenine
      nucleotides were secreted without loss of lactic dehydrogenase. Release took
      place well before the onset of irreversible aggregation. Inhibitors of platelet
      secretion or ADP induced aggregation could modify or prevent the irreversible
      clumping stimulated by small concentrations of PMA. Although the secretion
      induced by PMA differed from the release caused by other agents, the findings of
      the present study indicate that PMA is capable of triggering the platelet release
      reaction.

PMID- 4362918
TI  - Animal model of human disease. Malignant lymphoma.

PMID- 4362916
TI  - Experimental adenovirus infection of the mouse adrenal gland. I. Light
      microscopic observations.
AB  - A murine type of adenovirus has been found to have a highly selective affinity
      for the adrenal of its natural host. In view of the adrenal pathology in
      Addison's disease, which consists of cortical atrophy and focal lymphocytic
      infiltration, the possibility of a viral causation is an attractive hypothesis.
      The striking adrenotropism of this agent offers, theoretically, a potential
      experimental animal model for investigation of this possibility. Most of our
      information about the acute biologic action of adenoviruses has been gained from
      study of virus-infected tissue culture cells. The sharply focused and severe
      attack of the murine agent upon a prime target organ facilitates correlative in
      vivo studies of the cytopathology of adenovirus infection at levels of light and
      electron microscopy.

PMID- 4362917
TI  - Experimental adenovirus infection of the mouse adrenal gland. II. Electron
      microscopic observations.
AB  - A strain of mouse adenovirus, found to have a striking tropism for the weanling
      mouse adrenal gland, enabled electron microscopic examination of adrenals in
      various stages of infection. Nucleolar hypertrophy and the successive formation
      of three types of inclusion bodies in association with nucleoli preceded virion
      production. Angular crystals of virions formed in the affected nuclei. Virus was
      released by lysis of nuclear membranes; rapid degeneration of cytoplasmic
      organelles followed. Rupture of external cell membranes released virus into the
      extracellular spaces where virions crossed vascular basement membranes to enter
      endothelial cells. Virions were also phagocytized by inflammatory cells which
      reentered vascular sinusoids, and by adrenal parenchymal cells. Disruption of
      virus-laden phagocytic vacuoles in parenchymal cells released virions into the
      cytoplasm. Typical viral inclusion bodies also formed in vascular endothelial
      cells and in inflammatory cells, but virion replication was not detected. The
      possibility that virus directly entered parenchymal cells through the external
      cell membrane without phagocytosis is discussed.

PMID- 4362919
TI  - Spontaneous regression of cancer: the metabolic triumph of the host?

PMID- 4362920
TI  - Hypoglycemia associated with neoplasia.

PMID- 4362921
TI  - Paraneoplastic syndromes. Hyperadrenocorticism and ACTH-releasing factor.

PMID- 4362922
TI  - Neurogenic paraneoplastic syndromes. The brain's uneasy peace with tumors.

PMID- 4362923
TI  - Paraneoplastic syndromes of nerve muscle, and neuromuscular junction.

PMID- 4362924
TI  - The paraneoplastic syndromes associated with carcinoma of the thyroid gland.

PMID- 4362925
TI  - Why corticoids are effective against a wide variety of cancers.

PMID- 4362926
TI  - Epigenetic mechanisms and paraneoplastic phenomena.

PMID- 4362927
TI  - The processing of visual information in a simple retina.

PMID- 4362928
TI  - Two-hour embedding procedure for intracellular detection of viruses by electron
      microscopy.
AB  - An embedding method requiring only 2 h to complete and giving excellent
      ultrastructural preservation has been used for the rapid detection of viruses in
      tissue cultures. The method has also been applied successfully to mammalian
      tissue. It provides a rapid technique for identifying viruses isolated in tissue
      cultures, for screening cultures for adventitious agents, and for examining
      tissue biopsies for viruses.

PMID- 4362929
TI  - Utilization of a further miniaturized serological microtechnique.
AB  - A new 0.01-ml serological microtechnique system produced accurate and
      reproducible complement-fixation and indirect hemagglutination tests. This
      equipment involves the use of smaller amounts of antigens and sera, and thus
      increases the value of the method when employed with expensive reagents or
      limited qualities of sera.

PMID- 4362930
TI  - Exogenous and endogenous provocation of psoriasis. A contribution to the Koebner
      phenomenon.

PMID- 4362931
TI  - Experimental herpesvirus infection of baboons (Papio cynocephalus) and African
      green monkeys (Cercopithecus aethiops) and recovery of virus by tissue explants.

PMID- 4362932
TI  - Intracellular neutralization of poliovirus by type-specific antiserum.

PMID- 4362933
TI  - Non-infectious intracisternal A-type particles in a sarcoma-positive, leukemia
      negative mouse cell line transformed by murine sarcoma virus (MSV).

PMID- 4362934
TI  - Studies on temperature-sensitive events in synthesis of poliovirus ts mutants.

PMID- 4362936
TI  - Conformations of cyclic 3',5'-nucleotides. Effect of the base on the synanti
      conformer distribution.

PMID- 4362935
TI  - Feline "foamy" viruses: incidence in Australia.

PMID- 4362937
TI  - Nuclear columns: labeling and release of virus specific RNA by nuclei of DNA
      virus (SV 40) infected cells.

PMID- 4362939
TI  - A study of the interaction of human spermatozoa membrane with ATP and cyclic-AMP.

PMID- 4362938
TI  - Rapid, periodate-induced stimulation of permeability and macromolecular synthesis
      in chicken erythrocytes.

PMID- 4362940
TI  - Interaction of diethylpyrocarbonate with poliovirus double-stranded RNA.

PMID- 4362941
TI  - The oxidation state of newly synthesized hemoglobin.

PMID- 4362943
TI  - Metabolic regulation of steroidogenesis in adrenocortical carcinoma cells of rat.
      Effect of adrenocorticotropin and adenosine cyclic 3',5'-monophosphate on the
      incorporation of (20S)-20-hydroxy(7 alpha-3H)cholesterol into deoxycorticosterone
      and corticosterone.

PMID- 4362942
TI  - Synthesis of DNA complementary to AMV RNA using E. coli polymerase I.

PMID- 4362944
TI  - Synthesis of DNA, RNA protein and glycoprotein in mitochondria of cells
      transformed with Rous sarcoma viruses.

PMID- 4362946
TI  - Inhibition of choline kinase by selectively cytotoxic purinyl-6-histamine.

PMID- 4362945
TI  - Isolation of a divalent cation ionophore from beef heart mitochondria.

PMID- 4362947
TI  - Spin label translational diffusion in solid tristearin.
AB  - Translational diffusion of the intermediate chain length spin label 7N14 has been
      detected and studied in a lipid environment which is in the bulk solid state.
      Under favorable circumstances this can occur at temperatures as much as 50
      degrees C below the optical melting point. Translational diffusion allows 7N14
      molecules to coalesce into impurity pools of high spin label concentration. Two
      other spin labels, 2N3 and 14N27, do not show a tendency to form such impurity
      pools. While 2N3 undergoes rapid tumbling at temperatures far below the melting
      point of the tristearin matrix, the molecules remain in an isolated state with no
      evidence of spin exchange. 14N27 is restricted in rotational motion in the solid
      matrix and also does not form impurity pools.

PMID- 4362948
TI  - Calcium dependence of the inhibitory effect of angiotensin on renin secretion in
      the isolated perfused kidney of the rat.
AB  - 1 The effect of calcium on the inhibition of renin secretion by biologically
      active angiotensin was investigated in the isolated rat kidney perfused with
      Krebs-Ringer saline.2 In the presence of calcium (3.7 mM), asp(NH(2))'
      angiotensin II suppressed both basal and isoprenaline-stimulated renin secretion.
      Renal perfusion pressure, which was increased by the infusion of angiotensin,
      returned to control levels when isoprenaline was added.3 When the calcium
      concentration was reduced to 0.32 mM, the vasoconstriction produced by
      angiotensin was abolished although the inhibitory effect on renin secretion was
      still evident.4 In the absence of calcium, angiotensin no longer suppressed basal
      renin secretion and a prompt increase in renin secretion occurred when
      isoprenaline was added.5 The higher basal renin levels which were observed in
      calcium-free perfusions, suggest the existence of an intrarenal calcium-dependent
      mechanism that regulates basal renin secretion.6 These observations indicate that
      the inhibitory effect of biologically active angiotensin, on basal and
      isoprenaline-stimulated renin secretion, is functionally related to the
      contractor response by its dependence on calcium. The recognition that the renin
      producing cells are modified smooth muscle cells supports this association

PMID- 4362949
TI  - Studies on the coronary dilator actions of some adenosine analogues.
AB  - 1 The cardiovascular actions of 23 adenosine analogues have been examined in
      anaesthetized open thorax dogs; the analogues were substituted in the 2-position
      of the purine ring, or in the exocyclic amino group, or were modified in the
      imidazole or sugar rings.2 The effects of these compounds on coronary blood flow,
      peripheral blood pressure, and heart rate were compared with those of adenosine.3
      9-beta-D-Arabinofuranosyladenine had no cardiovascular action; the other
      analogues on intra-atrial administration caused an immediate increase in coronary
      blood flow, the magnitude and duration of which varied with the structures of the
      analogues.4 2-Fluoro-, 2-bromo-, 2-isobutylthio-, 2-ethylamino-, and 5'-deoxy-5'
      chloro- adenosines had coronary dilator potencies equal to or greater than that
      of adenosine. No relationship was found between the dilator potency of the
      adenosine analogues and their duration of coronary dilator action.5 The coronary
      dilator action of adenosine was potentiated by inosine, 9-beta-D-arabinofurano
      syladenine, tubercidin, N(6)-methyladenosine and 2-trifluoromethyl-N(6)
      methyladenosine.6 There was no correlation between the substrate specificities of
      the shorter-acting analogues for adenosine deaminase or adenosine kinase and
      their duration of coronary dilator action.7 It is proposed that in the
      anaesthetized dog, uptake into tissues is a more important mode of removal of
      adenosine and adenosine analogues from the vascular system than inactivation by
      adenosine deaminase, that the duration of coronary dilator action of the
      analogues is related primarily to their specificity for the carrier which
      mediates adenosine uptake, and that the adenosine carrier is not associated with
      kinase action.

PMID- 4362950
TI  - Morphine and neurotransmitter substances: Microiontophoretic study in the rat
      brain stem.
AB  - 1 The effects of microiontophoretically applied morphine and its interactions
      with the effects of microiontophoretic applications of either acetylcholine, (-)
      noradrenaline or 5-hydroxytryptamine have been studied on single neurones in the
      brain stem of rats anaesthetized with urethane.2 Morphine excited or inhibited
      most neurones tested and the effects, especially excitation, were often extremely
      powerful. However, the time course of the excitatory and inhibitory effects were
      somewhat different.3 Desensitization to the excitation produced by morphine was
      seen after repeated or prolonged applications and it is suggested that this
      phenomenon may be related to the tolerance which develops after chronic
      administration of morphine. No desensitization was observed to inhibition of
      neuronal activity by morphine.4 Morphine usually reduced the excitation of
      neurones by acetylcholine, noradrenaline or 5-hydroxytryptamine but sometimes
      potentiated the effect, although not always on the same neurones. Inhibition of
      neuronal activity by these compounds was never modified by morphine and neither
      were the effects of glutamate or D,L-homocysteic acid when used as control
      agonists.5 The in vitro release of morphine from six micropipettes was determined
      and the transport number was calculated to be 0.051 (s.d. 0.021).6 The
      implications of these observations in explaining the pharmacological actions of
      morphine are discussed.

PMID- 4362952
TI  - Non-epithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx: A
      clinicopathologic study. I. General features and vascular tumors.

PMID- 4362951
TI  - Studies on the tachyphylaxis to nicotinic stimulant drugs in the perfused
      hypogastric ganglion of the guinea-pig.
AB  - 1 The guinea-pig hypogastric ganglion, perfused through its vasculature with
      physiological saline solutions, will respond repeatedly to nicotinic stimulant
      drugs injected at 4 min intervals into the perfusion stream. Stimulation is
      indicated by contraction of the vas deferens. After a varying number of doses of
      nicotinic stimulants, complete tachyphylaxis usually develops, and normally this
      persists for at least 1 hour. During this time, however, electrical stimulation
      of the hypogastric nerve is still fully effective.2 Tachyphylaxis may be reversed
      for varying periods of time by all of the following procedures: (a) tetanic
      stimulation of the hypogastric nerve; (b) injection of large doses of histamine,
      methacholine, or potassium chloride; (c) perfusion with saline containing ouabain
      0.1 mug/ml or 80-100 mM lithium chloride, or, to a lesser extent, with potassium
      free saline.3 Tachyphylaxis is always re-established with further doses of
      nicotinic stimulants, except during perfusion with lithium solutions.4 Atropine
      hastens the onset of tachyphylaxis, but does not prevent its reversal by
      hypogastric nerve stimulation or by histamine or potassium. However, it does
      prevent the reversal by methacholine and by lithium.5 Tachyphylaxis occurs in
      decentralized ganglia, and can be reversed by histamine, methacholine, and by
      tetanic stimulation of the hypogastric ganglion. Hence tachyphylaxis and its
      reversal cannot be due to an effect on presynaptic fibres.6 Potassium chloride
      stimulates the ganglion both before and after tachyphylaxis has developed to
      nicotinic drugs, and hence this is unlikely to be due to a depolarization block.7
      It is concluded that tachyphylaxis could be due to a prolonged ganglionic
      hyperpolarization.

PMID- 4362953
TI  - Benign clear cell tumor of the lung. An ultrastructural study.

PMID- 4362954
TI  - Carcinoid tumor of the pancreas. Ultrastructural observations of a lymph node
      metastasis and comparison with bronchial carcinoid.

PMID- 4362956
TI  - Malignant and benign human mammary disease: estrogen binding in relation to
      clinical data.

PMID- 4362955
TI  - Sacrococcygeal teratoma with nephroblastoma (Wilm's tumor): a variant of
      extragonadal teratoma in childhood. A histologic and ultrastructural study.

PMID- 4362957
TI  - Childhood non-Hodgkin's lymphoma--a study of 17 cases in Israel.

PMID- 4362958
TI  - Bilateral nephroblastomatosis and Klippel Trenaunay syndrome.

PMID- 4362959
TI  - Familial occurrences of a variety of premalignant diseases and uncommon malignant
      neoplasms.

PMID- 4362960
TI  - Glutamine-dependent carbamyl phosphate synthetase during fetal and neonatal life
      in the rat.

PMID- 4362961
TI  - Changes in the activity of selected enzymes during starvation of Physarum
      polycephalum.

PMID- 4362962
TI  - Studies on the developmental pattern of the enzymes converting glucose 6
      phosphate to myo-inositol in the rat.

PMID- 4362963
TI  - Temporal effects of LH, hCG, FSH and dibutyryl cyclic 3',5'-AMP upon
      luteinization of rhesus monkey granulosa cells in culture.

PMID- 4362964
TI  - TSH stimulation of iodothyronine formation in prelabeled thyroglobulin of
      hypophysectomized rats.

PMID- 4362965
TI  - The preparation of biologically active 125I-labeled adrenocorticotrophic hormone
      by a simple enzymic radioiodination procedure utilizing lactoperoxidase.

PMID- 4362966
TI  - Effects of biogenic amines on the formation of adenosine 3',5'-monophosphate in
      porcine cerebral cortex, hypothalamus and anterior pituitary slices.

PMID- 4362967
TI  - 1Alpha-hydroxyvitamin D3: a synthetic sterol which is highly active in preventing
      rickets in the chick.

PMID- 4362968
TI  - Effects of hypophysectomy and ACTH on adrenocortical function in the rat.

PMID- 4362969
TI  - Responses of adipose tissue to sequential lipolytic stimuli.

PMID- 4362970
TI  - Autoradiographic localization of 3H-estradiol or its metabolites in the central
      nervous system of the developing rat.

PMID- 4362971
TI  - Stimulation of ketogenesis by dibutyryl cyclic AMP in isolated rat hepatocytes.

PMID- 4362972
TI  - Effects of prostaglandins on hepatic adenylate cyclase activity and cyclic
      adenosine 3',5',-monophosphate content.

PMID- 4362973
TI  - Apparent positive cooperative effects in cyclic AMP and corticosterone production
      by isolated adrenal cells in response to ACTH analogues.

PMID- 4362974
TI  - Angiographic analysis of factors influencing coronary artery bypass patency.

PMID- 4362975
TI  - [The angiographic investigation of functional disorders of renal transplants
      (author's translation)].

PMID- 4362976
TI  - [Post-operative angiography in assessing prognosis after reconstruction of
      chronic occlusions in the femoropopliteal territory (author's transl)].

PMID- 4362977
TI  - [Traumatic, non-perforating injury to the thoracic aorta and its intrathoracic
      branches (author's transl)].

PMID- 4362978
TI  - [Stenoses of multiple renal arteries and development of a reno-renal collateral
      circulation (author's transl)].

PMID- 4362979
TI  - [Simultaneous mediastinal phlebography and azygography (author's transl)].

PMID- 4362980
TI  - [Band-like pulmonary shadows in lungs caused by lymphangitis due to by Hodgkin's
      disease (author's transl)].

PMID- 4362982
TI  - [The radiological manifestations of pseudohypoparathyroidism and pseudo
      pseudohypoparathyroidism and their pathogenesis (author's transl)].

PMID- 4362981
TI  - [The signs of renal osteopathy seen on chest radiographs (author's transl)].

PMID- 4362983
TI  - [Familial primary vitamin D resistant rickets (phosphate diabetes). Observations
      of two cases--with and without therapy (author's transl)].

PMID- 4362984
TI  - [Xero-radiography for the demonstration of the skeleton and soft tissues
      (author's transl)].

PMID- 4362985
TI  - [Osteoplastic reactions in chronic gout (author's transl)].

PMID- 4362987
TI  - [Regression of cavitating lymphogranulomatous lung infiltrates following high
      voltage therapy].

PMID- 4362986
TI  - [Encephalo-tomographic investigation of sellar lesions (author's transl)].

PMID- 4362988
TI  - [A rare variant of the celiac-mesenteric trunk].

PMID- 4362989
TI  - [Bilateral variation in the course of the popliteal artery].

PMID- 4362991
TI  - [Circumscribed primary carcinoma of the upper jejunum].

PMID- 4362990
TI  - [Lymph node changes in cat-scratch disease (felinosis) as seen in the angiogram].

PMID- 4362992
TI  - Immunologic and genetic relationship between herpes simplex virus and bovine
      herpes mammillitis virus.

PMID- 4362993
TI  - Isolation of cold-sensitive mutants of poliovirus.

PMID- 4362994
TI  - Complementation and phenotypic stabilization of vesicular stomatitis virus
      temperature-sensitive and thermolabile mutants by avian myeloblastosis virus.

PMID- 4362995
TI  - Detection of virus-induced membrane and cytoplasmic antigens: comparison of the
      125I-labeled antiviral antibody binding technique with immunofluorescence.

PMID- 4362996
TI  - The effect of lorazepam on anxious insomniacs' sleep as recorded in the home
      environment.

PMID- 4362997
TI  - Relationship between cytomegalovirus and hepatic function abnormalities in the
      period after renal transplant.

PMID- 4362998
TI  - Cyclacillin: a clinical and in vitro profile.

PMID- 4362999
TI  - Binding of antibiotics to a soluble protein from rat liver.

PMID- 4363000
TI  - Neurologic complications associated with acute hemorrhagic conjunctivitis virus
      infection and its serologic confirmation.

PMID- 4363001
TI  - Cyclic 3',5'-nucleotide phosphodiesterase. I. Histochemical localization in rat
      skin.

PMID- 4363004
TI  - [Results of cytochrome C administration in leukopenia caused by radiotherapy].

PMID- 4363002
TI  - Effect of various methods of epidermal-dermal separation on the distribution of
      14C-acetate-labeled polyunsaturated fatty acids in skin compartments.

PMID- 4363003
TI  - [Radiographic finding of IIb type early gastric cancer--report of 1 typical IIb
      and 3 similar cases].

PMID- 4363005
TI  - [Autopsy case of alveolar cell carcinoma in a young female].

PMID- 4363006
TI  - The effect of various secretagogues on accumulation of cyclic AMP and secretion
      of alpha-amylase from rat exocrine pancreas.

PMID- 4363008
TI  - The influence of low and high doses of theophylline on spontaneous motility and
      cyclic 3',5' AMP content in isolated rat uterus.

PMID- 4363007
TI  - A spin label study of human erythrocyte ghost membranes damaged by methyl
      phenyldiazenecarboxylate (azoester).

PMID- 4363009
TI  - The role of calcium in the central effects of biogenic amines.

PMID- 4363010
TI  - A new class of angiotensin inhibitors: N-methylphenylalanine analogs.

PMID- 4363011
TI  - Specific angiotensin II receptors in organ-cultured canine supra-optic nucleus
      cells.

PMID- 4363012
TI  - Magnesium and contraction of arterial smooth muscle.

PMID- 4363013
TI  - Effect of angiotensin and norepinephrine on capillary pressure and filtration
      coefficient in isolated dog hindlimb.

PMID- 4363014
TI  - Inhibition of adenosine cyclic 3', 5'-monophosphate accumulation in fat cells by
      adenosine, N6-(phenylisopropyl) adenosine, and related compounds.

PMID- 4363015
TI  - Superinduction of serotonin N-acetyltransferase and supersensitivity of adenyl
      cyclase to catecholamines in denervated pineal gland.

PMID- 4363016
TI  - Effect of nerve degeneration by 6-hydroxydopamine on catecholamine-stimulated
      adenosine 3',5'-monophosphate formation in rat cerebral cortex.

PMID- 4363017
TI  - Effects of the carcinogen N-acetoxy-2-fluorenylacetamide on the template
      properties of deoxyribonucleic acid.

PMID- 4363018
TI  - Induction of aryl hydrocarbon hydroxylase in mouse 3T3 cells: relationship to the
      state of cell proliferation and guanosine cyclic 3',5'-monophosphate.

PMID- 4363019
TI  - Changes in a surface-labelled galactoprotein and in glycolipid concentrations in
      cells transformed by a temperature-sensitive polyoma virus mutant.

PMID- 4363020
TI  - Androgen receptors in a Syrian hamster ductus deferens tumour cell line.

PMID- 4363021
TI  - Serotonin and pituitary-adrenal function.

PMID- 4363022
TI  - The structural and functional organization of the thyroid gland and special
      features of the tumours of this organ.

PMID- 4363024
TI  - [Reducing of mature height in a girl with body overlength (author's transl)].

PMID- 4363023
TI  - [Pregnantriolon excretion after ACTH-stimulation in possible heterocygotes of 21
      hydroxylase deficiency (author's transl)].

PMID- 4363025
TI  - [Selective medium for Clostridium perfringens. II. Selective medium with sodium
      azide and crystal violet for isolation of Clostridium perfringens].

PMID- 4363027
TI  - Percutaneous transhepatic cholangiography.

PMID- 4363026
TI  - Letter: Effect of exogenous oestrogens on minor psychiatric symptoms in
      postmenopausal women.

PMID- 4363029
TI  - [Rat liver mitochondrial permeability for NAD+ during the action of DDT and sevin
      on the animals].

PMID- 4363028
TI  - Enlargement of cavernous haemangioma associated with exogenous administration of
      oestrogens.

PMID- 4363030
TI  - [Effect of systematic muscular work on the tissue activity of adenylate cyclase
      and 3',5'-AMP-phosphodiesterase].

PMID- 4363031
TI  - [Current concepts concerning the role of cyclic-AMP as a regulator of enzyme
      activity].

PMID- 4363032
TI  - [The effect of different combinations of antibacterial preparations on the
      activity of several enzymes in the tissues of guinea pigs with experimental
      tuberculosis].

PMID- 4363033
TI  - [Induction of "alkaline" and "acid" DNAases in cultures of cells infected with
      cytomegalovirus].

PMID- 4363034
TI  - Morphological and histochemical study on the major salivary glands of mice
      injected with dactinomycin.

PMID- 4363035
TI  - A simple apparatus and procedure for digestion of biologic materials in
      determinations of nonvolatile elements.

PMID- 4363036
TI  - Pre-Descemet's membrane corneal dystrophy.

PMID- 4363037
TI  - Sporotrichosis of the orbital margin.

PMID- 4363038
TI  - Protective immunity to amebic infection demonstrated in guinea pigs.

PMID- 4363039
TI  - Schistosomiasis and other human parasitoses of Lake Lindu in central Sulawesi
      (Celebes), Indonesia.

PMID- 4363040
TI  - Immunological reactions in kuru. Attempts to demonstrate serological
      relationships between karu and other known infectious agents.

PMID- 4363041
TI  - The use of excisional therapy in the management of snakebite.

PMID- 4363042
TI  - Dual primary bronchogenic carcinoma.

PMID- 4363043
TI  - Genetic control of resistance to mouse cytomegalovirus infection.

PMID- 4363044
TI  - Comparison of the neuraminidases of three avian paramyxoviruses.

PMID- 4363045
TI  - Heterogeneity of rabbit serum interferon induced by poly I:C.

PMID- 4363046
TI  - Activation of herpes specific antigens and infectious virus in a hamster cell
      line transformed by HSV-2.

PMID- 4363047
TI  - [The stability of amphetaminil and benzalamphetamine].

PMID- 4363048
TI  - Distribution of bound ADP-ribose derivatives in nuclear protein of rat liver
      nuclei.

PMID- 4363049
TI  - The isolation and the structure of new glycopeptide from blood group substances.

PMID- 4363050
TI  - Neurospora crassa and Humicola lanuginosa cytochromes c: more homology in the
      heme region.

PMID- 4363051
TI  - Isolation of plasma membranes from bovine corpus luteum possessing adenylate
      cyclase, 125I-hCG binding and Na-K-ATPase activities.

PMID- 4363053
TI  - Biosynthesis of a P1-2-acetamido-2-deoxy-D-glucosyl P2-polyisoprenyl
      pyrophosphate by calf pancreas microsomes.

PMID- 4363052
TI  - The activation of motility in quiescent hamster sperm from the epididymis by
      calcium and cyclic nucleotides.

PMID- 4363054
TI  - Yeast mutants requiring ergosterol as only lipid supplement.

PMID- 4363055
TI  - The effect of prostaglandins E1 and E2 on the human erythrocyte as monitored by
      spin labels.

PMID- 4363056
TI  - Mechanism of stimulation of Ca2+ plus Mg2+ -dependent phospodiesterase from rat
      cerebral cortex by the modulator protein and Ca2+.

PMID- 4363057
TI  - Structural polypeptides of primate derived type C RNA tumor viruses.

PMID- 4363058
TI  - Morphologic variations of a cell strain transformed by simian papovavirus SV40
      and cloned serially.

PMID- 4363059
TI  - The epidermal disorder in lichen planus: an in vitro study.

PMID- 4363060
TI  - Deoxynucleotide-polymerizing enzymes in normal and malignant human cells.

PMID- 4363061
TI  - The delayed and lasting rejection of mammary adenocarcinoma cell tumors in DBA-2
      mice with use of killed Bordetella pertussis.

PMID- 4363062
TI  - Fetal-leukemic antigen of chicken blood cells.

PMID- 4363063
TI  - Effect of murine milk samples and human breast tissues on human leukocyte
      migration indices.

PMID- 4363064
TI  - Suppression of SV40 tumors after immunization with group A Streptococcus pyogenes
      and Bordetella pertussis.

PMID- 4363065
TI  - Steroid delta 4 -reductase activity in hepatomas of differentgrowth rates.

PMID- 4363066
TI  - Patterns of excretion of methylated purines in hepatocellular carcinoma.

PMID- 4363067
TI  - Persistence and expression of the herpes simplex virus type 2 genome in cervical
      tumor cells.

PMID- 4363068
TI  - Development of preimplantation rabbit embryos in vivo and in vitro. I. An
      ultrastructural comparison.

PMID- 4363069
TI  - [Incidence of banal infections in childhood and possibilities of their
      prevention].

PMID- 4363070
TI  - Intradiem changes of plasma aldosterone, cortisol, corticosterone and growth
      hormone in sodium restriction.

PMID- 4363071
TI  - An unusual case of Cushing's syndrome, hilus cell tumor and polycystic ovaries.

PMID- 4363072
TI  - Responsiveness of human subjects to human growth hormone: relation to bone age.

PMID- 4363073
TI  - Correlations of serum triglyceride and prebetalipoprotein levels to the severity
      of spontaneous diabetes in Macaca nigra.

PMID- 4363074
TI  - Effect of chlorpropamide on osmotic water flow across toad bladder and the
      response to vasopressin, theophylline and cyclic AMP.

PMID- 4363075
TI  - Thyroid hormone action: demonstration of putative nuclear receptors in human
      lymphocytes.

PMID- 4363076
TI  - Big renin: a possible prohormone in kidney and plasma of a patient with Wilm's
      tumor.

PMID- 4363077
TI  - Bioavailability of different sources of dietary iron fed to Pitman-Moore
      miniature pigs.

PMID- 4363078
TI  - Body fluid and electrolyte balance during estrogen therapy of prostatic cancer.

PMID- 4363079
TI  - Webbed penis.

PMID- 4363080
TI  - Regulation of phosphorylase B to A conversion in muscle.

PMID- 4363081
TI  - Adenosine-elicited accumulation of cyclic AMP in brain slices: potentiation by
      agents which inhibit uptake of adenosine.

PMID- 4363082
TI  - Cartilage cyclic nucleotide phosphodiesterase: inhibition by anti-inflammatory
      agents.

PMID- 4363083
TI  - Excretion and degradation of exogenous adenosine 3',5'-monophosphate by isolated
      perfused rat kidney.

PMID- 4363084
TI  - [Diagnostics of relapse in hodgkin's disease (author's transl)].

PMID- 4363085
TI  - Zinc ions inhibit replication of rhinoviruses.

PMID- 4363086
TI  - Genetic evidence for SV40 gene function in enhancement of replication of human
      adenovirus in simian cells.

PMID- 4363087
TI  - No crossing over between closely linked tumour virus loci in the heterogametic
      sex of fowl.

PMID- 4363088
TI  - [Lipidosis of the nervous system following chlorphentermine administration].

PMID- 4363090
TI  - Temporal discrimination of short intervals of dreamless sleep.

PMID- 4363089
TI  - Prostaglandin-dependent and -independent feedback control of noradrenaline
      secretion in vasoconstrictor nerves of normotensive human subjects. A preliminary
      report.

PMID- 4363091
TI  - Effects of "short-term" versus "long-term" L-Dopa therapy in parkinsonism on
      critical flicker frequency.

PMID- 4363092
TI  - Familial type II hyperlipoproteinaemia. Clinical features and results of
      treatment in children and young adults.

PMID- 4363093
TI  - [Effect of folic and orotic acids and vitamin B-12 on the lysosomal enzymatic
      activity in the hippocampus and cerebral cortex of rats training].

PMID- 4363094
TI  - [Glucose-6-phosphate dehydrogenase, transketolase and glucose-6-phosphatase
      activity in the rat liver with a varying provision of corticosteroids and ACTH].

PMID- 4363095
TI  - [Changes in lipid metabolism in rats exposed to chronic inhalation of quartz
      dust].

PMID- 4363096
TI  - [Method of extracting and fractionating brain tissue phosphoinositides].

PMID- 4363097
TI  - Pigment movements in fish melanophores: morphological and physiological studies.

PMID- 4363098
TI  - Pigment movements in fish melanophores: morphological and physiological studies.
      3. The effects of colchicine and vinblastine.

PMID- 4363099
TI  - The fine structure of the kidney of Achatina achatina (L).

PMID- 4363100
TI  - Structure and permeability of the septate junction in the kidney sac of Helix
      pomatia L.

PMID- 4363101
TI  - Ultrastructure of motor nerve terminals on different types of muscle fibers in
      the Atlantic hagfish (Myxine glutinosa, L.). Occurrence of round and elongated
      profiles of synaptic vesicles and dense-core vesicles.

PMID- 4363102
TI  - Total gastrectomy for cancer of the stomach.

PMID- 4363103
TI  - Postnatal development of the lateral vestibular nucleus (Deiters' nucleus) of the
      rat. A light and electron microscopic study.

PMID- 4363104
TI  - Conjunctival papillomas in siblings.

PMID- 4363105
TI  - Benign mixed tumor of the (palpebral) lacrimal gland presenting as a nodular
      eyelid lesion.

PMID- 4363107
TI  - Partial REM sleep deprivation, schizophrenia and field articulation.

PMID- 4363106
TI  - Epithelial inclusion cyst of iris after keratoplasty.

PMID- 4363108
TI  - Physiocochemical properties of low-density lipoproteins of normal human plasma.
      Evidence for the occurrence of lipoprotein B in associated and free forms.
AB  - 1. Low-density (d 1.006-1.063g/ml) lipoproteins from normal human plasma were
      separated by differential preparative ultracentrifugation into six subfractions.
      Each low-density (LD) lipoprotein subfraction contained lipoprotein B as the
      major and lipoproteins A and C as the minor lipoprotein families. 2. Three
      lipoprotein B subfractions (LP-B), LP-B-III (d 1.019-1.030g/ml), LP-B-IV (d 1.030
      1.040g/ml) and LP-B-V (d 1.040-1.053g/ml) were prepared from the corresponding LD
      lipoprotein subfractions by immunoprecipitating small amounts of lipoproteins A
      and C. 3. Determination of hydrodynamic properties indicated that LD lipoproteins
      consisted of three molecular segments characterized by a stepwise change in the
      molecular weight: LDL-I and LDL-II subfractions (d 1.006-1.019g/ml) with an
      average mol.wt. of 4.75x10(6), LDL-III (d 1.019-1.030g/ml) with a mol.wt. of
      3.99x10(6), and LDL-IV, LDL-V and LDL-VI (d 1.030-1.063g/ml) with a mol.wt. of
      2.85x10(6). 4. All three lipoprotein B subfractions had an average mol.wt. of
      3.16x10(6). 5. The LDL-I and LDL-II subfractions consisted of lipoprotein B and
      lipoprotein C families which were present in the form of an association complex.
      This was isolated from serum by immunoprecipitation with antibodies to
      lipoprotein B. The complex had a mol.wt. of 4.35x10(6). 6. The results indicate a
      fundamental difference between the LD lipoprotein subfractions with d 1.006
      1.019g/ml and those subfractions with d 1.030-1.063g/ml. In the former,
      lipoprotein B occurs as a part of an association complex, whereas in the latter
      it occurs as a separate entity.

PMID- 4363109
TI  - Studies on partially reduced mammalian cytochrome oxidase. Reactions with carbon
      monoxide and oxygen.
AB  - A number of methods were used to prepare a species of mammalian cytochrome
      oxidase (EC 1.9.3.1, ferrocytochrome c-oxygen oxidoreductase) in which only
      cytochrome a(3) is reduced and in combination with CO. The kinetics of CO binding
      by cytochrome a(3) (2+) in this species is significantly different from that
      exhibited by cytochrome a(3) (2+) in the fully reduced enzyme. The second-order
      rate constant for combination was 5x10(4)m(-1).s(-1) and the ;off' constant was
      3x10(-2)s(-1). The kinetic difference spectra cytochrome a(3) (2+)-cytochrome
      a(3) (2+)-CO reveal further differences between the mixed-valence and the fully
      reduced enzyme. The reaction between cytochrome a(3) (2+) and oxygen in the mixed
      valence species was followed in flow-flash experiments and reveals a fast, oxygen
      dependent (8x10(7)m(-1).s(-1) at low oxygen) rate followed by a slow process,
      whose rate is independent of oxygen but whose amplitude is dependent on [O(2)].
      The fast oxygen-dependent reaction yields as the first product the so-called
      ;oxygenated' enzyme. We conclude from these experiments that the ligand-binding
      behaviour of cytochrome a(3) depends on the redox state of its partners, a fact
      which represents clear evidence for site-site interaction in this enzyme. The
      fact that oxygen reacts rapidly with this enzyme species in which only one
      component, namely cytochrome a(3), is reduced represents clear and unequivocal
      evidence that this is indeed the O(2)-binding site in cytochrome oxidase and may
      indicate that reduction of oxygen can proceed via single electron steps.

PMID- 4363110
TI  - Separation at neutral pH value of 32P-labelled proteins in a membrane preparation
      from ox brain. Partial characterization of component of the sodium-plus-potassium
      ion-activited adenosine triphosphatase.
AB  - 1. Ox brain microsomal fractions were labelled with [(32)P]ATP in the presence of
      Na(+) and the reaction was stopped with sodium dodecyl sulphate. The Na(+)
      dependent bound phosphate was isolated on Sephadex G-25 and by acetone
      precipitation. The bound phosphate isolated under these neutral conditions was
      labile to hydroxylamine and gave the same pH profile of hydrolysis as that
      isolated by precipitation with strong acids. 2. When membrane protein was
      labelled with [(32)P]ATP, solubilized with sodium dodecyl sulphate and
      fractionated on Sepharose 6B, the Na(+)-dependent label emerged in a peak
      corresponding to protein of molecular weight 570000-580000. On fractionation of
      this protein peak on polyacrylamide gels containing detergent and urea, the Na(+)
      dependent label occurred in a single band corresponding to a protein of molecular
      weight 102000. 3. Fractionation on Sepharose 6B of protein labelled with
      [(32)P]ATP in the absence of Na(+) revealed three labelled peaks, one of which
      corresponded in position to the Na(+)-dependent label. Electrophoresis of this
      peak material on polyacrylamide gels showed that most of the label occurred in
      two fast-running bands. Cyclic AMP stimulated the labelling in these two bands,
      but had no effect on the labelling of the band corresponding in position to the
      Na(+)-dependent label. 4. Di-isopropyl [(32)P]phosphorofluoridate also labelled
      the band corresponding to the Na(+)-dependent label on gel electrophoresis. The
      labelling of this band by the reagent was inhibited by 50-60% by 3mm-ATP, but
      there was no evidence to suggest that the group labelled is normally
      phosphorylated by ATP.

PMID- 4363111
TI  - The molecular basis for biological inactivation of nucleic acids. The action of
      methylating agents on the ribonucleic acid-containing bacteriophage R17.
AB  - 1. The inactivation of an RNA-containing bacteriophage after reaction with four
      methylating agents was studied. Measurements of the extent of methylation of the
      RNA and of the nature and amounts of the various reaction products were made. In
      experiments with dimethyl sulphate and methyl methanesulphonate inactivation can
      be quantitatively accounted for by methylation at two of the positions involved
      in hydrogen bonding: N-1 of adenine and N-3 of cytosine. In experiments with N
      methyl-N-nitrosourea and N-methyl-N'-nitro-N-nitrosoguanidine methylation at N-1
      of adenine and N-3 of cytosine accounts for only about one-half of the observed
      inactivation. Scission of the RNA chain during reaction accounts for a further
      20% of the inactivation. To account for the remainder it seems necessary to
      postulate that formation of O(6)-methylguanine constitutes a lethal lesion. 2.
      Breaks in the RNA chain formed on reaction with the nitroso derivatives
      presumably result from methylation of the phosphate diester group followed by
      hydrolysis of the unstable triester thus formed.

PMID- 4363112
TI  - The reaction of alkylating agents with bacteriophage R17. Biological effects of
      phosphotriester formation.
AB  - The extent of biological inactivation and of the degradation of the RNA after
      reaction of bacteriophage R17 with ethyl methanesulphonate, isopropyl
      methanesulphonate and N-ethyl-N-nitrosourea was studied. Formation of breaks in
      the RNA chain probably results from hydrolysis of phosphotriesters formed in the
      alkylation reactions. Near neutral pH the ethyl and isopropyl phosphotriesters
      are sufficiently stable for the kinetics of the hydrolysis reaction to be
      followed. Results indicate that the rate of hydrolysis increases rapidly as the
      pH is raised. The evidence shows that a phosphotriester group does not itself
      constitute a lethal lesion. The extent of phosphotriester formation by the
      different agents is discussed in terms of reaction mechanism.

PMID- 4363114
TI  - Fluorescence studies of protein-sterol relationships in human plasma
      lipoproteins.
AB  - Cholesta-5,7,9(11)-trien-3beta-ol and its oleate ester were incorporated into
      human low-density lipoprotein and reconstituted high-density lipoprotein. The
      unesterified sterol was more efficient than its ester in quenching tryptophan
      fluorescence, especially in low-density lipoprotein. The results, which indicate
      that in such lipoproteins unesterified sterols are more closely associated with
      peptide than are esterified sterols, are used to assess possible structures for
      the lipoproteins.

PMID- 4363113
TI  - A specific collagenase from rabbit fibroblasts in monolayer culture.
AB  - 1. Explants of rabbit skin and synovium in tissue culture secreted a specific
      collagenase into their culture media. Primary cultures of fibroblast-like cells,
      which were obtained from these tissues and maintained in culture for up to 14
      subculture passages, also secreted high activities of a specific collagenase into
      serum-free culture medium. Secretion of enzyme activity from the cell monolayer
      was at constant rate for over 100h and continued for up to 8 days in serum-free
      culture medium. The enzymic activity released was proportional to the number of
      cells in the monolayer. 2. The fibroblast collagenase was maximally active
      between pH7 and 8. At 24 degrees C the collagenase decreased the viscosity of
      collagen in solution by 60%. The collagen molecule was cleaved into three
      quarters and one-quarter length fragments as demonstrated by electron microscopy
      of segment-long-spacing crystallites (measured as native collagen molecules
      aligned with N-termini together along the long axis), and by polyacrylamide-gel
      electrophoresis of the denatured products. The collagenase hydrolysed insoluble
      collagen, reconstituted collagen fibrils and gelatin, but had no effect on
      haemoglobin or Pz-Pro-Leu-Gly-Pro-d-Arg (where Pz=4-phenylazobenzyloxycarbonyl).
      3. The fibroblast collagenase was partially purified by gel filtration and the
      molecular weight was estimated as 38000. The activity of the partially purified
      enzyme was stimulated by 4-chloromercuribenzoate, inhibited by EDTA, cysteine,
      1,10-phenanthroline and serum, but was unaffected by di-isopropyl
      phosphorofluoridate, Tos-LysCH(2)Cl and pepstatin. 4. Long-term cell cultures
      originating from rabbit skin or synovium from rabbits with experimentally induced
      arthritis also secreted specific collagenase. Human fibroblasts released only
      very small amounts of collagenase.

PMID- 4363115
TI  - Studies on the topography of the fat cell plasma membrane.

PMID- 4363116
TI  - Interaction of actin with spin-labeled heavy meromyosin in the presence of
      nucleotides.

PMID- 4363117
TI  - Exchangeability of bicarbonate specifically bound to transferrin.

PMID- 4363118
TI  - Proton magnetic resonance study of angiotensin II (Asn1Va15) in aqueous solution.

PMID- 4363119
TI  - Purification and characterization of a steroid receptor from chick embryo liver.

PMID- 4363120
TI  - A circular dichroism study of the secondary structure of bradykinin.

PMID- 4363121
TI  - Selective incorporation of host cell methionyl-transfer RNA by RNA tumor viruses.

PMID- 4363122
TI  - Inactivation of aminoacyl-tRNA synthetases by amino acid chloromethylketones.

PMID- 4363123
TI  - Drug-induced renal medullary necrosis. II. Mode of calcification in the kidney.

PMID- 4363125
TI  - Dibutyryl cyclic AMP: increase in viral particles associated with morphologic
      changes in leukemic cells.

PMID- 4363124
TI  - Dietary induced hyperbetalipoproteinemia in chimpanzees: comparison to the human
      hyperlipoproteinemia.

PMID- 4363126
TI  - Phagocytosis of injured hepatocytes following inoculation with
      encephalomyocarditis virus.

PMID- 4363127
TI  - Lysosomes of the arterial wall. II. Subcellular fractionation of aortic cells
      from rabbits with experimantal atheroma.

PMID- 4363128
TI  - Mast cells: extended lifespan and lack of granule turnover under normal in vivo
      conditions.

PMID- 4363129
TI  - [Peau d'orange--an unreliable sign of diffuse carcinoma of the breast].

PMID- 4363130
TI  - [Thyroid angiography: involvement of vertebral artery in a malignant thyroid
      gland lesion].

PMID- 4363131
TI  - [Lymphographic findings in plasmacytoma].

PMID- 4363132
TI  - [Complete esophageal rupture].

PMID- 4363133
TI  - [Bleeding Meckel's diverticulum in the size of a man's fist].

PMID- 4363135
TI  - [Osteopoikilosis in a dicephalo-thoracopagus (radiographic and pathologo
      anatomical findings)].

PMID- 4363134
TI  - [Unusual picture of a hydronephrotic pelvic kidney].

PMID- 4363136
TI  - [Radiological aspects of artifical hip joints (author's transl)].

PMID- 4363137
TI  - [Problems common to radio-diagnosis, radiological physics and radio-biology
      (author's transl)].

PMID- 4363138
TI  - [The angiographic appearances of carcinoid of the intestinal tract (author's
      transl)].

PMID- 4363139
TI  - [The radiological appearances of the stomach and duodenum following nonexcisional
      operations for gastric and duodenal ulcers (author's transl)].

PMID- 4363140
TI  - [Discreet mucosal changes in the colon (author's transl)].

PMID- 4363141
TI  - [Contrast accumulation in the liver due to obstruction of the retro-peritoneal
      lymphatic paths (author's transl)].

PMID- 4363142
TI  - [Angiographic studies of radiation-induced renal lesions. Animal experimental
      studies and clinical observation].

PMID- 4363143
TI  - [An angiographic contribution to the patho-physiology of the renal circulation
      (author's transl)].

PMID- 4363144
TI  - [The radiological diagnosis of non-chromaffin paragangliomas in the head and neck
      (author's transl)].

PMID- 4363146
TI  - [Radiation exposure of people working in radiological diagnostics].

PMID- 4363145
TI  - [The demonstration of arterio-venous shunts in the lower extremities using 131I
      MAA and 99mTc microspheres after lumbar sympathectomy (author's transl)].

PMID- 4363147
TI  - [Biomedical properties of pions].

PMID- 4363148
TI  - Consideration of some problems in dosimetry and radiobioloby of stopped negative
      pions.

PMID- 4363149
TI  - Timing of ovulation in a sterility clinic.

PMID- 4363150
TI  - "Uterine progesterone system (U.P.S.)": a new form of intrauterine contraception.
      Preliminary report.

PMID- 4363151
TI  - Immunochemical studies on human seminal plasma. 3. Ultracentrifugal studies on
      human seminal plasma and a purified fraction.

PMID- 4363152
TI  - Daily urinary excretion of follicle stimulating (FSH) and luteinizing hormone
      (LH) immediately after menarche.

PMID- 4363153
TI  - Hydrotubation.

PMID- 4363154
TI  - Effect of HCG on plasma levels of estrogens and progesterone during the luteal
      phase of the menstrual cycle in rhesus monkeys (Macaca mulatta). Stimulation of
      sex steroid production in Rhesus monkeys.

PMID- 4363155
TI  - Immunological similarity of placenta in human and Rhesus monkey.

PMID- 4363156
TI  - Post "pill" amenorrhoea.

PMID- 4363157
TI  - Zinc and magnesium in human spermatozoa from different fractions of split
      ejaculates.

PMID- 4363158
TI  - Long-term therapy with low-dose cisclomiphene in male infertility: effects on
      semen, serum FSH, LH, testosterone ond estradiol, and carbohydrate tolerance.

PMID- 4363159
TI  - In vitro release and uptake of zinc and magnesium by human spermatozoa.

PMID- 4363160
TI  - Sperm antibody production in female sterility.

PMID- 4363162
TI  - Unconventional nucleotide analogues. Synthesis of N-substituted 3-(adenin-9
      yl)pyrrolidin-2-ones.

PMID- 4363161
TI  - Human vascular endothelial cells in culture. Growth and DNA synthesis.
AB  - Human endothelial cells, obtained by collagenase treatment of term umbilical cord
      veins, were cultured using Medium 199 supplemented with 20% fetal calf serum.
      Small clusters of cells initially spread on plastic or glass, coalesced and grew
      to form confluent monolayers of polygonal cells by 7 days. Cells in primary and
      subcultures were identified as endothelium by the presence of Weibel-Palade
      bodies by electron microscopy. A morphologically distinct subpopulation of cells
      contaminating some primary endothelial cultures was selectively subcultured, and
      identified by ultrastructural criteria as vascular smooth muscle. Autoradiography
      of endothelial cells after exposure to [(3)H]thymidine showed progressive
      increases in labeling in growing cultures beginning at 24 h. In recently
      confluent cultures, labeling indices were 2.4% in central closely packed regions,
      and 53.2% in peripheral growing regions. 3 days after confluence, labeling was
      uniform, being 3.5 and 3.9% in central and peripheral areas, respectively. When
      small areas of confluent cultures were experimentally "denuded," there were
      localized increases in [(3)H]thymidine labeling and eventual reconstitution of
      the monolayer. Liquid scintillation measurements of [(3)H]thymidine incorporation
      in primary and secondary endothelial cultures in microwell trays showed a similar
      correlation of DNA synthesis with cell density. These data indicate that
      endothelial cell cultures may provide a useful in vitro model for studying
      pathophysiologic factors in endothelial regeneration.

PMID- 4363163
TI  - Haemagglutinating antigen prepared from Yaba-1 virus (strain Lednice-110) by
      ultrasonic disintegration.

PMID- 4363164
TI  - Cystosarcoma phylloides.

PMID- 4363165
TI  - Chiropractic: a challenge for health education.

PMID- 4363166
TI  - Morphogenesis of chemically induced neoplasms of the colon and small intestine in
      rats.

PMID- 4363167
TI  - [Alcohol in the metabolism--transfer of hydrogen atoms].

PMID- 4363168
TI  - Virus productive transformation of marsupial cells by Schmidt-Ruppin strain of
      RSV.

PMID- 4363169
TI  - DNA synthesis in "nuclear monolayers" from BSC-1 cells infected with herpes
      virus.

PMID- 4363170
TI  - Oestradiol inhibition of collagenase role in uterine involution.

PMID- 4363171
TI  - With reference to the effect of pituitary hormones on lymphocyte blastogenesis in
      cell-culture.

PMID- 4363173
TI  - [X-ray examination of ossification foci in the knee joint and maturity of the
      newborn infant].

PMID- 4363172
TI  - [Paragangliomas in the records of the Institute of Oncology in Cracow].

PMID- 4363174
TI  - [Synacthen-depot treatment during withdrawal of long-term corticotherapy in
      patients with asthma].

PMID- 4363175
TI  - [Bone scintigraphy with 99m Tc polyphosphates (author's transl)].

PMID- 4363176
TI  - [Excretion of cytomegalovirus in healthy children during the first year of life].

PMID- 4363177
TI  - [Biological and learning-theory aspects of addictive behavior].

PMID- 4363178
TI  - Non-simultaneous bilateral breast carcinoma.

PMID- 4363179
TI  - Measurement of hepatic blood flow in man.

PMID- 4363180
TI  - [Radiation therapy in cerebral neoplasms].

PMID- 4363182
TI  - [Comparing investigations of two hemostyptics on patients with prostatectomy
      (author's transl)].

PMID- 4363181
TI  - [Pulmonary fibrosis following mega-volt irradiation diagnosed as pulmonary
      tuberculosis].

PMID- 4363183
TI  - [The ultrastructure of mixed mammary gland tumours in bitches. II. The incidence
      of myoepithelial cells in chondroid areas (author's transl)].

PMID- 4363184
TI  - [Ultrastructural study of an amyloid-producing insuloma. Discussion on
      histogenesis of focal amyloidosis (author's transl)].

PMID- 4363185
TI  - [Mucous cancer of the rectum in a 13-year-old boy].

PMID- 4363186
TI  - [The effect of thymectomy, irradiation and immunization of C3H-He line mice on
      the development of syngenous mammary gland tumors].

PMID- 4363187
TI  - [Lymphography of the inguinal, iliac and para-aortic lymph nodes].

PMID- 4363188
TI  - [Immunomorphologic features of human myogenic tumors].

PMID- 4363189
TI  - [Concerning the viral etiology of tumors].

PMID- 4363190
TI  - [Proof of the existence of antigens in virus induced mammary gland tumors of
      mouse line CBA-Bln].

PMID- 4363191
TI  - [The effect of nucleic acid from Rous chicken sarcoma on cultures of embryonal
      human and chicken cells].

PMID- 4363192
TI  - [The concentration of glycogen and the activity of enzymes involved in its
      synthesis in experimental tumors and in the liver].

PMID- 4363193
TI  - The reaction of the preoptic nucleus of Xenopus laevis to osmotic stimulation. An
      enzyme cytochemical investigation.

PMID- 4363194
TI  - [Simultaneous outbreak of bursitis and infectious bronchitis with the nephritis
      nephrosis syndrome].

PMID- 4363195
TI  - [Visna virus-like particles in cultures of choroid plexus cells of a goat with
      symptoms of Visna infection].

PMID- 4363196
TI  - [The immune peroxidase method for demonstration of viral and chlamydial antigens.
      I. Methodological principles and herpesvirus equi-1-antigen in the liver of
      infected golden hamsters].

PMID- 4363197
TI  - Cyclic AMP as a regulator of thymidine kinase.

PMID- 4363198
TI  - Transformed estrogen receptor in the regulation of RNA synthesis in uterine
      nuclei.

PMID- 4363200
TI  - Functional studies of polysome-membrane interactions in vitro.

PMID- 4363199
TI  - Alterations of complex lipid metabolism in tumorigenic virus transformed cell
      lines.

PMID- 4363201
TI  - A study of the hormonal control in vitro of Na+-K+ activated ATPase of isolated
      liver plasma membrane.

PMID- 4363202
TI  - Glycogen synthetases and phosphorylases in rat hepatomas.

PMID- 4363204
TI  - Ordered and specific pattern of gene expression in neoplasia.

PMID- 4363203
TI  - Some regulatory mechanisms in the synthesis of urea in the mammalian liver.

PMID- 4363205
TI  - [Methods for rapid diagnosis of viral respiratory tract infections by indirect
      immunofluorescence].

PMID- 4363206
TI  - Role of gastrin in hypersecretory disorders in man.

PMID- 4363207
TI  - Antiviral chemotherapy.

PMID- 4363208
TI  - Crystal deposition joint disease.

PMID- 4363209
TI  - Vitamin D metabolism.

PMID- 4363210
TI  - The cell surface and malignant transformation.

PMID- 4363212
TI  - Properties of alcohol dehydrogenase isozymes in a strain of Drosophila
      melanogaster homozygous for the Adh-slow allele.

PMID- 4363211
TI  - Sulfonylureas and the heart.

PMID- 4363213
TI  - Effects of morphine on the gluconeogenic enzymes from rat liver in vivo.

PMID- 4363214
TI  - Absence of an effect of histamine, noradrenaline and depolarizing agents on the
      levels of adenosine 3', 5'-monophosphate in nerve endings isolated from cerebral
      cortex.

PMID- 4363216
TI  - Effect of collagenase pretreatment on choline and acetylcholine release from
      slices of bovine superior cervical sympathetic ganglia.

PMID- 4363215
TI  - Effect of lithium on prostaglandin F1-stimulated adenylate cyclase activity of
      human platelets.

PMID- 4363217
TI  - Inhibition of cAMP phosphodiesterase by disodium cromoglycate.

PMID- 4363218
TI  - [Transmission of stimulation in the ganglial synaptic structures of the heart and
      its alteration under the influence of catecholamines].

PMID- 4363219
TI  - [Effect of steroid hormones on the development of deciduomas in the rat uterus
      with intact and disorderd innervation].

PMID- 4363220
TI  - The effects of inhaled beclomethasone dipropionate (Becotide) and sodium
      cromoglycate on asthmatic reactions to provocation tests.

PMID- 4363221
TI  - Percutaneous trigeminal tractotomy. Variations in delineation of the obex using
      emulsified Pantopaque.

PMID- 4363222
TI  - A radioautographic study on the mechanisms by which adrenal glucocorticoids play
      their permissive role in the biological activity of cyclic AMP in the liver cell.

PMID- 4363223
TI  - On the activity of cathepsin C in human embryonic kidney cell cultures infected
      with Herpesvirus hominis (Herpes simplex).

PMID- 4363224
TI  - Inhibition of beef heart and rat brain nucleoside-3':5'-monophosphate
      phosphodiesterase by 3beta-14-dihydroxy-21-oxo-23-desoxo-5-beta-card-20(22)
      enolide 3-acetate (AY-17,605) and structurally related compounds.

PMID- 4363225
TI  - [Behavior of mastocytes in the rat treated with potassium perchlorate].

PMID- 4363226
TI  - Oncogenic viruses in the thrombocytopenic stage of experimental HIPA
      plasmacytoma.

PMID- 4363228
TI  - [The effect of arfonad on the transmission of excitation in the intracradiac
      ganglion].

PMID- 4363227
TI  - Selective potentiating effects of metal ions on vasopressin.

PMID- 4363229
TI  - Leukocytosis-promoting factor of Bordetella pertussis. 3. Its identity with
      protective antigen.
AB  - Leukocytosis-promoting factor (LPF) was purified from the supernatant of a 5-day
      liquid culture of Bordetella pertussis strains Tohama and no. 134. The
      preparations appeared to be filamentous molecules (2 by 40 nm) and contained
      histamine-sensitizing and hemagglutinin activities in addition to leukocytosis
      promoting activity. Active protection tests in mice demonstrated strong
      protective activities of 80 international protective units per mg of protein in
      LPF preparations of each strain toxoided by mild Formalin treatment. Passive
      protection tests in mice with anti-LPF sera indicated that anti-LPF is one of the
      protective antibodies.

PMID- 4363230
TI  - Delayed-type hypersensitivity and immunity against aerogenic tuberculosis in
      guinea pigs.
AB  - In experiments described herein, it was observed that guinea pigs with delayed
      type hypersensitivity to tuberculoproteins under various experimental conditions,
      with or without passive transfer of serum from immune donors, manifested no
      acquired immunity against aerogenically induced tuberculosis. These results are
      discussed in relation to the previous observations of other investigators and to
      the general problem of cellular hypersensitivity and immunity against facultative
      intracellular bacteria.

PMID- 4363231
TI  - Glycolysis during early infection of feline and human cells with feline leukemia
      virus.
AB  - A 30 to 40% increase in glucose uptake and lactic acid production was observed
      during a 48-h period immediately following inoculation of feline fibroblasts and
      HEp-2 cells with feline leukemia virus. There was no evidence of morphological
      alterations in either cell type. Immunofluorescent procedures to detect feline
      leukemia virus group-specific antigen revealed that the feline and HEp-2 cells
      were infected, whereas the antigen was not found in parallel cultures of
      uninoculated cells. Increased glycolysis depends upon the physiological state of
      the host cell and was not observed with infected stationary-phase cells.

PMID- 4363233
TI  - Anti-cardiolipin and anti-phosphatidylglycerol antibodies prepared against
      bacterial phospholipids.
AB  - Anti-phosphatidylglycerol and anti-cardiolipin antisera were prepared in rabbits
      by using phospholipids purified from Micrococcus lysodeikticus. Anti
      phosphatidylglycerol antibodies were found in antisera when either
      phosphatidylglycerol or cardiolipin were used as immunogens, but adsorption
      studies indicated they were not similar. Antibodies which reacted with
      phosphatidylinositol and phosphatidic acid were also found in the anti
      cardiolipin antiserum. Structures of the antigenic groups in phosphatidylglycerol
      and cardiolipin are suggested from cross-reaction and adsorption studies.
      Adsorption studies with pure phospholipid antigens indicated the importance of
      the spacial orientation of phospholipid haptens for immunological reactivity.

PMID- 4363232
TI  - Physicochemical fractionation of extracellular cornea-damaging proteases of
      Pseudomonas aeruginosa.
AB  - Fractionation of the culture supernatant fluids of a cornea-virulent strain of
      Pseudomonas aeruginosa by ammonium sulfate precipitation, diafiltration,
      isoelectric focusing, ion-exchange chromatography, gel filtration, and sucrose
      density gradient centrifugation failed to separate the rabbit cornea-damaging
      activity and the in vitro protease activity of the preparations. Three proteases
      having similar molecular weights (approximately 20,000) and isoelectric points of
      approximately 4.6, 5.8, and 8.8 were obtained free of detectable amounts of other
      known extracellular pseudomonal enzymes. Heating a mixture of the three proteases
      for 15 min at 80 C resulted in complete loss of protease and cornea-damaging
      activities. The sterile culture filtrate of a nonproteolytic but lethal toxin
      producing strain of P. aeruginosa did not contain cornea-damaging activity.
      Cultivation of the proteolytic strain in broth containing 4.7% ammonium sulfate
      yielded a culture supernatant fluid free of protease and cornea-damaging
      activities. The results obtained support the conclusion that a cornea-virulent
      strain of P. aeruginosa can produce, in vitro, at least three different
      extracellular proteases capable of eliciting rapid and extensive damage to rabbit
      corneas.

PMID- 4363234
TI  - Cross-protection between group B arboviruses: resistance in mice to Japanese B
      encephalitis and St. Louis encephalitis viruses induced by Dengue virus
      immunization.
AB  - Albino Swiss mice, immunized with any of several types and strains of dengue
      viruses, were afforded substantial protection against peripheral Japanese B
      encephalitis or St. Louis encephalitis virus challenge. Dengue-2 (New Guinea "C")
      immunized mice showed, 10 and 20 weeks after immunization, undiminished
      resistance with concomitant cyclophosphamide treatment and virus challenge.
      Examination of the effects of immunization on Japanese B encephalitis virus
      pathogenesis, after virus challenge with concomitant cyclophosphamide treatment,
      indicated that protection was associated with decreased viremia and virtually no
      virus replication in the brain as compared with controls. These effects could be
      demonstrated before detection of any neutralizing antibody to the challenge
      virus. From the applied aspect, the data support the hypothesis, based on
      epidemiological evidence and experiments in hamsters, that prior exposure of man
      to dengue viruses can confer some degree of protection against Japanese B
      encephalitis or St. Louis encephalitis disease.

PMID- 4363236
TI  - Evidence that neurons harbor latent herpes simplex virus.
AB  - The cell type(s) harboring latent herpes simplex virus in the spinal ganglia of
      mice was investigated. Taken together, results from immunofluorescence, electron
      microscopic, autoradiographic, and in situ nucleic acid hybridization methods
      suggest strongly that, in mice, latent virus is maintained in neurons.

PMID- 4363235
TI  - Mutation in Shigella flexneri resulting in loss of ability to penetrate HeLa
      cells and loss of glycerol kinase activity.
AB  - A colonial variant of a virulent Shigella flexneri 2a has lost both virulence and
      glycerol kinase activity. It also has several other altered characteristics:
      lowered ability to oxidize tricarboxylic acid cycle intermediates, increased
      electrophoretic mobility, and decreased sensitivity to sodium lauryl sulfate.
      Genetic analysis has revealed that the gene governing glycerol kinase activity in
      Shigella has a different chromosomal locus than that from Escherichia coli.
      Furthermore, transduction of the Shigella glycerol kinase gene (glp K) into the
      avirulent Shigella strain can restore the ability to penetrate HeLa cells,
      whereas the gene from E. coli cannot. About half of the glp K mutants lose this
      ability, and only about half of the revertants of an avirulent glp K mutant
      regain it. This indicates that more than one gene affects glycerol kinase
      activity in Shigella, only one of which is associated with penetration. Glycerol
      kinase activity is closely correlated with changes in electrophoretic mobility,
      but does not appear to have any relationship to sodium lauryl sulfate sensitivity
      nor to the oxidation of tricarboxylic acid cycle intermediates.

PMID- 4363238
TI  - Pleomorphic adenoma of the thyroid containing salivary gland cells with
      pseudocartilage and myoepithelial cells.

PMID- 4363237
TI  - Pseudomonas infections of skin: an experimental study.

PMID- 4363239
TI  - Preparation and use of surface-modified adsorbents in clean-up techniques for
      pesticide residue analysis.

PMID- 4363240
TI  - Bilateral mixed tumors occurring simultaneously in major and minor salivary
      glands.

PMID- 4363241
TI  - Horny cell formation in the epidermis of Rana pipiens.

PMID- 4363242
TI  - [Origin and destination of plasmatic lactatae].

PMID- 4363243
TI  - [Cortico-adrenal response to neurotropic and systemic agressions after
      corticosteroid injection].

PMID- 4363244
TI  - Inability of adenosine 3':5'-cyclic monophosphate to simulate fully the effects
      of LH in rabbit ovaries.

PMID- 4363246
TI  - Synthesis of avian oncornavirus DNA in infected chicken cells.
AB  - The intracellular synthesis and integration of viral DNA (vDNA) into the host
      cell genome was studied in cultured chicken embryo fibroblasts infected with
      avian sarcoma or leukemia viruses. The newly synthesized vDNA was detected by
      hybridization with 70S viral RNA. Extraction of infected cell DNA by the
      selective procedure of Hirt resulted in the enrichment of newly synthesized vDNA
      in the low molecular weight supernatant fraction while leaving the bulk of
      cellular DNA containing integrated vDNA in the high molecular weight pellet
      fraction. This approach led to detection of intracellular vDNA synthesis within 1
      h after infection and to vDNA integration into cellular DNA within 24 h. There
      was a several-fold increase in the vDNA content of infected cells during the
      initial phase of virus infection. But only a part of this newly synthesized vDNA
      appeared to become covalently linked with high molecular weight cellular DNA.
      Most of the remaining unintegrated vDNA gradually disappeared. The sedimentation
      profiles of minimally sheared cellular DNA in alkaline sucrose velocity gradients
      suggest that vDNA is synthesized as free linear molecules of approximately 3 x
      10(6) daltons which subsequently are covalently linked to host cell DNA.

PMID- 4363245
TI  - Activation of the murine sarcoma virus genome after infection with the murine
      leukemia virus as determined by cell agglutination.
AB  - Non-virus-producing NIH/3T3 cells transformed by the murine sarcoma virus are
      agglutinated by conconavalin A to the same low level as normal NIH/3T3 cells.
      Infection with the murine leukemia virus greatly increases the agglutination of
      transformed cells but not that of normal cells. These data suggest that the
      morphological expression of cell transformation and the surface alterations
      associated with increased cell agglutination are controlled by the expressions of
      different sarcoma virus genes.

PMID- 4363247
TI  - Comparison of two human papovaviruses with simian virus 40 by structural protein
      and antigenic analysis.
AB  - The proteins of simian virus 40 (SV40) and two human papovaviruses, the
      hemagglutinating BK virus and the non-hemagglutinating DAR virus, were analyzed
      and compared by sodium dodecyl sulfate polyacrylamide gel electrophoresis. The
      virions of SV40 and DAR contain seven proteins. By molecular weight analysis the
      constituent proteins of SV40 and DAR are identical. Approximately 84% of the
      viral protein has a molceular weight of 45,000. The major protein of BK virus is
      3,000 to 5,000 daltons lighter than the major proteins of SV40 and DAR viruses.
      The five most rapidly migrating proteins of BK virus are indistinguishable by
      molecular weight analysis from the corresponding proteins of SV40 and DAR
      viruses. Radial immunodiffusion and immunoelectrophoresis of whole virus gave
      lines of identity between SV40 and DAR when reacted with SV40 antibody. SV40
      antiserum tested against BK virus and BK antiserum tested against SV40 virus
      showed no reactivity by complement fixation, immunodiffusion, or
      immunoelectrophoresis.

PMID- 4363248
TI  - Effect of ionic strength on the binding of Sindbis virus to chick cells.
AB  - Sindbis virus can adsorb to chicken embryo fibroblasts in two different ways.
      "Loosely" bound virus can be washed off the cell with buffers of ionic strength
      0.2 or greater, whereas "tightly" bound virus remains attached under these
      conditions. When Sindbis virus is adsorbed to chick cells at 4 C from a buffer of
      ionic strength 0.17, 40 to 50% of the adsorbed virus is loosely bound, the
      remainder tightly bound. Infection of chick cells by Sindbis virus has only small
      effects on the total amount of virus that can be bound to the cells. However, the
      amount of Sindbis virus that can be tightly bound declines rapidly beginning at 2
      to 3 h after infection. By 7 h after infection, the amount of virus that can be
      tightly bound is only 10 to 20% of the amount bound to uninfected cells. The
      adsorption (and penetration) of virus at 37 C is most efficient at an ionic
      strength of 0.15 to 0.17; at this ionic strength most of the adsorbed virus is
      tightly bound. At higher ionic strengths the virus adsorbs poorly. At lower ionic
      strengths most of the virus is loosely bound. A second enveloped virus, vesicular
      stomatitis virus, has been studied for the purposes of comparison; its adsorption
      behavior differs from that of Sindbis virus.

PMID- 4363250
TI  - Location of the origin of DNA replication in adenovirus Type 2.
AB  - Utilizing the isolated left and right halves of both adenovirus type 2 and the
      nondefective adenovirus simian virus 40 hybrid (Ad2(+)ND(1)), studies were
      undertaken to find the site on the DNA molecules at which replication begins. The
      data are consistent with several models which include an initiation event at both
      ends and bidirectional growth.

PMID- 4363249
TI  - Analysis of a viral agent isolated from multiple sclerosis brain tissue:
      characterization as a parainfluenzavirus type 1.
AB  - A virus originally isolated from cell cultures obtained by lysolecithin-induced
      fusion of human multiple sclerosis brain cells with CV-1 cells has been analyzed
      for its antigenic, RNA, and polypeptide compositions, and for selective
      biological properties. Our findings establish that this isolate, designated 6/94
      virus, contains a 50S RNA genome and is, as yet, indistinguishable from Sendai
      virus in its antigenic and total polypeptide compositions. Despite these
      similarities, the 6/94 and Sendai viruses differ in certain phenotypic
      properties. 6/94 virus is markedly less cytocidal for chick fibroblasts,
      especially at 37 C and, after beta-propiolactone inactivation, it possesses a
      greater capacity for cell fusion and a lower toxicity than does comparably
      treated Sendai virus. In addition, 6/94 virus shows greater hemolytic activity.

PMID- 4363251
TI  - Polyadenylation of vesicular stomatitis virus mRNA.
AB  - Vesicular stomatitis virus (VSV) mRNA isolated from infected cell polysomes
      contains polyadenylic acid [poly(A)] sequences. Detergent-activated purified
      virions in vitro can transcribe complementary RNA, which has sedimentation
      properties similar to mRNA, and this RNA also contains poly(A) sequences.
      Digestion of virion RNA with U2 RNase under conditions where hydrolysis is
      specific for purine linkages leaves no sequences of polyuridylic acid
      corresponding in length to the poly(A) on the transcripts. Growth of infectious
      virus is not inhibited by 3-deoxyadenosine (cordycepin) under conditions in which
      it inhibits polyadenylation of cellular mRNA. The virus-specific mRNA produced in
      the presence of cordycepin has poly(A) sequences of the same size distribution as
      that synthesized in the absence of cordycepin.

PMID- 4363252
TI  - Poliovirus infection and poly(A) sequences of cytoplasmic cellular RNA.
AB  - The influence of polio infection on Poly(A) sequences of cellular cytoplasmic RNA
      was investigated. In the presence of guanidine, cellular protein synthesis was
      still shut off after poliovirus infection, although there was no viral RNA
      synthesis. The Poly(A) of these cells was unchanged with respect to quantity,
      size, and linkage to cellular cytoplasmic RNA. This finding strongly suggests
      that the shut off of cellular protein synthesis is not caused by a change of the
      Poly(A) sequences of cellular mRNA.

PMID- 4363253
TI  - Complementation analysis of simian virus 40 mutants.
AB  - Seventy six new temperature-sensitive mutants of simian virus 40 have been
      isolated. A simple modification of the standard plaquing technique permits
      complementation analyses to be performed readily. By using this technique the new
      mutants have been divided into four complementation groups.

PMID- 4363254
TI  - Separation of B and C type virions by centrifugation in gentle density gradients.
AB  - Murine type B particles were separated from type C (Rauscher leukemia virus) by
      means of gentle (low-increment rate) density gradients. The best separation was
      obtained when the density ranged from 1.13 to 1.20 g/cm(3) when sucrose was used
      and from 1.12 to 1.28 g/cm(3) with CsCl. The buoyant densities of the B and C
      particle bands in sucrose were 1.18 and 1.16 g/cm(3), respectively. The CsCl
      gradient gave a better separation with the B particles banding at a density of
      1.20 g/cm(3) and with the C particle density little different from its value in
      sucrose.

PMID- 4363255
TI  - Isolation and partial characterization of different defective DNA molecules
      derived from polyoma virus.
AB  - Supercoiled DNA molecules purified from mouse cells infected with high
      multiplicity-passaged polyoma virus has a broader size distribution and sediments
      more slowly than DNA derived from low-multiplicity-passaged virus. The shorter
      DNA molecules are predominately noninfectious. Virus populations containing
      distinct size classes of defective virus DNA were isolated by growing virus from
      single cells infected by a defective and nondefective helper virus (infectious
      center). This technique probably results in the cloning of defective virus
      particles. By applying the infectious center method to DNA from various fractions
      of sucrose gradients it has been possible to obtain shorter circular DNA
      molecules ranging in size from 50 to 95% of the unit-length polyoma DNA molecule.
      The shorter molecules in any one preparation are homogeneous in size. This class
      size is retained upon repeated passage of crude viral lysates at high
      multiplicity. Thus far, all the purified shorter DNA molecules tested appear to
      be noninfectious and largely resistant to cleavage by the R(1) restriction
      enzyme. Some of the purified defective molecules have been found to interfere
      with the production of infectious virus upon co-infection with unit-length
      infectious polyoma DNA.

PMID- 4363257
TI  - [Community nursing--reform].

PMID- 4363258
TI  - [Community nursing without future?].

PMID- 4363256
TI  - Surface membrane glycopeptides which coincide with virus transformation and
      tumorigenesis.
AB  - Glycopeptides from the surface of clones of hamster embryo cells were examined at
      various intervals after infection with polyoma virus. Two types of transformed
      cells were examined: (i) clones that showed delayed transformation or an
      initially low tumorigenicity, and (ii) clones that were rapidly transformed
      showing an initially high tumorigenicity. The glycopeptides were removed from the
      cell surface by trypsin and, after Pronase digestion, were examined by filtration
      through Sephadex G-50. With delayed transformation, a specific group of
      glycopeptides was increasingly evident over an 85-day period as the cells showed
      phenotypic properties of transformation and the ability to form tumors. In the
      other series, all but one clone of hamster embryo cells showed rapid
      transformation after infection with polyoma virus. This clone was less
      tumorigenic and showed little of the specific glycopeptides. In all cases of
      delayed or rapid transformation examined, the specific group of glycopeptides
      increased proportionately to the ability of the cells to form tumors. All of the
      cells derived from progressively growing tumors formed by injection of these
      transformed hamster cells into adult animals showed an abundance of this group of
      glycopeptides. These results suggest that specific surface membrane glycopeptides
      accompany viral transformation and tumorigenesis.

PMID- 4363259
TI  - [Nursing shift end and personnel scheduling organization in pediatric wards].

PMID- 4363260
TI  - [Anesthesia and intensive care. 3. Administering the anesthesia].

PMID- 4363261
TI  - [Radiology. IV. Protection against risks in the use of ionizing irradiation].

PMID- 4363262
TI  - [Conclusions and proposals for education and continued education in nursing].

PMID- 4363263
TI  - [Nursing--ready for the university?].

PMID- 4363264
TI  - ["Where are the lunatics?"].

PMID- 4363265
TI  - [Place of employement, hospital].

PMID- 4363266
TI  - [The working climate in the hospital].

PMID- 4363267
TI  - [Mangement in the hospital].

PMID- 4363268
TI  - [Social work problems in the industrial community].

PMID- 4363270
TI  - [Medical services of the federal army in peacetime].

PMID- 4363269
TI  - [Location and efficiency of the hospital social service from the nursing service
      viewpoint].

PMID- 4363271
TI  - [Radiology. V. The cooperation of nursing personal in roentgenology and nuclear
      medicine].

PMID- 4363273
TI  - [Radiation protection--when? where? who?].

PMID- 4363272
TI  - [Anesthesia and intensive care. IV. Termination of anesthesia].

PMID- 4363275
TI  - [Dimensions of organized learning processes].

PMID- 4363274
TI  - [Anesthesia and intensive care. V. Diagnostic and therapeutic nerve blocks].

PMID- 4363276
TI  - [Help by the mother in the hospital. Visiting hours in the pediatric ward].

PMID- 4363277
TI  - [Pampered children have to suffer].

PMID- 4363278
TI  - [Biological effect of energy-rich radiation used in medicine].

PMID- 4363279
TI  - [Physical bases of energy-rich radiation used in medicine].

PMID- 4363280
TI  - [Current roentgen diagnosis--principles and possibilities of special diagnostic
      procedures].

PMID- 4363282
TI  - [Functional diagnosis and scintigraphy. Examples from nuclear medicine
      diagnosis].

PMID- 4363281
TI  - [Megavolt therapy--radiotherapy with modern heavy apparatus].

PMID- 4363283
TI  - Toward control of tumour and virus growth by helical RNA. II. Difference in the
      post-integrational control of virus synthesis by Poly I:C in acutely and
      chronically B77 virus infected cells.

PMID- 4363284
TI  - Possiblity of cancer diagnosis by detection of Clostridial antibodies.

PMID- 4363286
TI  - Congenital mesoblastic nephroma of infancy.

PMID- 4363285
TI  - Lesions in sheep skeletal and oesophageal muscle in vermeersiekte (Geigeria
      ornativa O. Hoffm. poisoning).

PMID- 4363287
TI  - [The effect of Actinomyces fradiae 119 proteinases, trypsin and Clostridium
      histolyticum collagenase on insoluble collagen from the Achilles tendon].

PMID- 4363288
TI  - [Purification of the intracellular ribonucleases of Aspergillus clavatus].

PMID- 4363289
TI  - [Determination of glycerol dehydratase activity by the method of coupled enzyme
      reactions].

PMID- 4363290
TI  - Cell surface receptors--structure and function.

PMID- 4363291
TI  - Platelet function in health and disease.

PMID- 4363292
TI  - Origin and formation of lymph lipids in the sheep.

PMID- 4363293
TI  - Calcification of oral bacteria: an ultrastructural study of two strains of
      Bacterionema matruchotii.

PMID- 4363294
TI  - Amniogenic bands as a cause of syndactyly in a young human fetus.

PMID- 4363295
TI  - [Cytologic diagnosis of bronchial carcinoid].

PMID- 4363296
TI  - [A histogenetic analysis of benign lung tumors].

PMID- 4363297
TI  - [Metastasis of experimental tumors and the functional activity of the hypophysis
      adrenal system].

PMID- 4363298
TI  - [Late results of breast cancer treatment].

PMID- 4363299
TI  - [Non-epithelial tumors of the stomach].

PMID- 4363300
TI  - [An analysis of errors and causes of late diagnosis of malignant soft tissue
      tumors].

PMID- 4363301
TI  - [Treatment of rheumatoid arthritis in children with tetracosactide beta-24].

PMID- 4363303
TI  - An autopsy case of primary cytomegalic inclusion enteritis with remarkable
      hypoproteinemia.

PMID- 4363302
TI  - Mucous substance and enzyme histochemistry of non-neoplastic and neoplastic
      gastric epithelium in man.

PMID- 4363304
TI  - A note on fine structure of synovial sarcoma.

PMID- 4363305
TI  - Studies on animal collagenase.

PMID- 4363306
TI  - On the turnover of acetylcholine in the brain. An experimental study using
      intravenously injected radioactive choline.

PMID- 4363307
TI  - [Histopathological studies of hepatic lesions in hamsters inoculated with
      different strains of E. histolytica under axenic conditions].

PMID- 4363308
TI  - [Enzyme activity of E. histolytica from axenic and monoxenic cultures.
      Histochemical study in vivo and in vitro].

PMID- 4363309
TI  - [Comparative study of pathogenic and nonpathogenic E. histolytica strains with
      light microscopy and immunofluorescent reactions].

PMID- 4363310
TI  - [Tissue reaction in experimental primary infection and reinfection with axenic
      and monoxenic cultures of E. histolytica].

PMID- 4363311
TI  - [Cellular hypersensitivity in amebiasis. I. Reactions in hamsters inoculated with
      E. histolytica].

PMID- 4363312
TI  - [Immunity after axenic amebic antigen injection in the hamster].

PMID- 4363313
TI  - [Immunity after cured amebic infection in the hamster].

PMID- 4363314
TI  - [Immunity in hamsters after vaccination with monoxenic acid axenic cultures of E.
      histolytica].

PMID- 4363315
TI  - [Further experiments on the effect of estrogens in hamsters with amebiasis of the
      liver].

PMID- 4363317
TI  - [Transplacental transmission of antibodies against E. histolytica].

PMID- 4363316
TI  - [Comparison between trophozoites of E. histolytica from asymptomatic carriers and
      those obtained from patients with amebic lesions].

PMID- 4363318
TI  - Some current concepts and concerns relative to amebae and disease in man.

PMID- 4363319
TI  - [Electron microscopy of the intranuclear round bodies of E. histolytica. After
      treatment with desoxyribonuclease and ribonuclease].

PMID- 4363320
TI  - [Study of sialic acid in the exterior cover of trophozoites of Entamoeba
      histolytica. Biochemical study and high resolution cytochemistry].

PMID- 4363321
TI  - [Selective agglutination of trophozoites of various strains of E. histolytica
      induced by concanavalin].

PMID- 4363322
TI  - [Erythrophagia and leukophagia by E. histolytica trophozoites with and without
      exterior cover. Study by electron microscopy and high resolution cytochemistry].

PMID- 4363323
TI  - [Morphodynamic response of trophozoites of E. histolytica to the action of their
      corresponding human immune serum].

PMID- 4363324
TI  - [Study in vitro of the pharmacological action of antiamebic drugs].

PMID- 4363325
TI  - Virulence of axenically cultivated E. histolytica.

PMID- 4363326
TI  - Studies on antibody surveillance to EB virus-induced antigen in patients with
      sarcoidosis and nasopharyngeal carcinoma by indirect immunofluorescence.

PMID- 4363327
TI  - Aberrant forms of varicella-zoster virus.

PMID- 4363328
TI  - Control of flagellum formation in Naegleria gruberi.

PMID- 4363329
TI  - Electron-phonon (trapped photon) coupling and infrared coaxial transmission line
      theory of energy transport in mitochondria and nerve.

PMID- 4363334
TI  - Electron optic analysis of human dentin in hypophosphatemic vitamin D-resistant
      rickets (report of a kindred with consanguinity).

PMID- 4363333
TI  - Metabolic pathways and control mechanisms involved in the biosynthesis and
      turnover of collagen in normal and pathological connective tissues.

PMID- 4363335
TI  - Collagen metabolism in pericoronitis.

PMID- 4363336
TI  - [Proceedings: 5. EPR study of peroxidation catalyzed by hemeproteins (author's
      transl)].

PMID- 4363337
TI  - [Proceedings: 6. ESR studies of Cu++ in the liquid-crystalline of phospholipids
      (author's transl)].

PMID- 4363338
TI  - [Proceedings: 43. Participation of cytoplasmic inclusions in producing the
      birefringence signal from nerve fibers (author's transl)].

PMID- 4363339
TI  - [Proceedings: 137. The effect of angiotensin II on the gluconeogenesis in rabbit
      liver (author's transl)].

PMID- 4363340
TI  - Proceedings: 155. Role of brain biogenic amines in the regulation of ACTH
      secretion in the rat.

PMID- 4363341
TI  - Current therapy approaches of the Division of Cancer Treatment with emphasis on
      pancreatic carcinoma.

PMID- 4363342
TI  - [Vagotomy in duodenal ulcer].

PMID- 4363343
TI  - A study of the mechanism of the formation of the unproductive lactate
      dehydrogenase-NAD-pyruvate ternary complex.

PMID- 4363344
TI  - Conformational analysis of globular proteins by optical rotatory dispersion.

PMID- 4363345
TI  - Fine structure of the magnetooptical rotatory dispersion curves and the
      surroundings of heme in ferrocytochrome c and its model compounds.

PMID- 4363346
TI  - [Indirect hemagglutination test for research of anti-cytomegalovirus antibodies].

PMID- 4363348
TI  - [Proceedings: Enzymatic equipment and staphylococcal typing].

PMID- 4363349
TI  - [Proceedings: Technical considerations and statistical evaluations on the
      determination of some enzymes performed with instruments for automatic analysis
      and with an analyzer for kinetic enzymes].

PMID- 4363350
TI  - Proceedings: A new rapid method of enzymic analysis using rate reaction
      techniques.

PMID- 4363347
TI  - In vitro studies on the nature of prostaglandin E1 binding in the hamster uterus.

PMID- 4363351
TI  - [Proceedings: Relationship of serum cholinesterase level in chronic alcoholic
      liver disease and appearance of delirium tremens: therapeutic effect of oximes].

PMID- 4363352
TI  - [Proceedings: Isolactate dehydrogenase activity in human sperm].

PMID- 4363353
TI  - [Proceedings: Technical considerations and diagnostic evaluation in the
      determination of lactate dehydrogenase isoenzymes].

PMID- 4363354
TI  - [Proceedings: Significance of free glycerol level in the enzymatic determination
      of serum triglycerides].

PMID- 4363355
TI  - [Proceedings: New methodological improvement in the determination of GLDH].

PMID- 4363357
TI  - Inhibition of 3',5'-cyclic AMP phosphodiesterase with anti-inflammatory agents.

PMID- 4363356
TI  - Inhibition of 3',5'-cyclic AMP phosphodiesterase by acid mucopolysaccharides and
      sulfopolysaccharides.

PMID- 4363358
TI  - Enhancement of the hepatotoxicity of trichloroethylene by inducers of drug
      metabolism.

PMID- 4363359
TI  - The effect of apyrase on platelet retention in normal subjects and in patients
      with abnormal cardiac valves or with von Willebrand's disease.

PMID- 4363360
TI  - Experimental observations on the effects of physical training upon intrinsic
      cardiac physiology and biochemistry.

PMID- 4363361
TI  - Effects of prostaglandins E1 and E2 on renal sodium reabsorption and Starling
      forces.

PMID- 4363362
TI  - Fever produced in the squirrel monkey by intravenous and intracerebral endotoxin.

PMID- 4363363
TI  - Brush-border processes and transepithelial Na and Cl transport by rabbit ileum.

PMID- 4363364
TI  - Effects of ADH and other agents on cyclic AMP accumulation in toad bladder
      epithelium.

PMID- 4363365
TI  - Effects of hormones on cyclic AMP formation in kidneys of nonmammalian
      vertebrates.

PMID- 4363366
TI  - Dibutyryl cyclic AMP and potassium transport in cardiac Purkinje fibers.

PMID- 4363367
TI  - Recovery of poliovirus from turbid estuarine water on microporous filters by the
      use of celite.
AB  - The application of a new step for recovering poliovirus from moderately to highly
      turbid estuarine water by the filter virus-adsorption technique was investigated.
      The experiments were conducted under both (i) laboratory-based conditions (200-ml
      volumes) where the turbidity was controlled and (ii) simulated field conditions
      (15- to 100-gal volumes) where the turbidity varied depending upon the hydrology
      of the raw estuarine water. The new step consisted of adding Celite to the turbid
      water prior to sampling for virus. In the experiments, the pH of the water was
      first adjusted to 3.5 and then AlCl(3) was added to 0.0005 M. Celite was added to
      a concentration of 0.01% and mixed thoroughly. Either an HE Cox M-780 microfilter
      (Cox Instrument, Div. of Lynch Corp., Detroit, Mich.) or an MF-membrane filter
      (Millipore Corp., Bedford, Mass.) was used as the virus adsorbent. Virus was
      eluted from the Celite-filter complex in situ at pH 9 with 5x nutrient broth. In
      the laboratory-based experiments, when turbidity ranged from 5.0 to 30.0 Jackson
      turbidity units (JTU), virus recovery ranged from 66 to 89%. In the simulated
      field experiments, when the turbidity ranged from 8.5 to 80.0 JTU, virus recovery
      ranged from <1 to 74%, depending upon the multiplicity of virus input and the
      level of turbidity. The new step greatly improved the filtration-flux of turbid
      water and significantly reduced the premature clogging problem usually observed
      with microporous filters.

PMID- 4363368
TI  - Enumeration of food-borne Clostridium perfringens in egg yolk-free tryptose
      sulfite-cycloserine agar.
AB  - The SFP (Shahidi-Ferguson perfringens), TSC (tryptose-sulfite-cycloserine), EY
      (egg yolk)-free TSC, and OPSP (oleandomycin-polymyxin-sulfadiazine perfringens)
      agars have been tested for their suitability to enumerate Clostridium perfringens
      in naturally contaminated foods. Complete recoveries of C. perfringens were
      obtained in each of the four media, but only the TSC and EY-free TSC agars were
      sufficiently selective to ensure subsequent confirmatory tests without
      interference from facultative anaerobes. Because of some disadvantages associated
      with the use of egg yolk, EY-free TSC agar is recommended for enumeration of C.
      perfringens in foods. Several conditions for convenient shipment of foods and C.
      perfringens isolates with minimum loss of viability have been tested. The highest
      viable counts were preserved when foods were mixed 1:1 (wt/vol) with 20% glycerol
      and kept in a container with dry ice. Isolated C. perfringens strains remained
      viable for at least 2 weeks at ambient temperatures on blood agar slopes with a
      2% agar overlay in screw-cap culture tubes.

PMID- 4363369
TI  - Enumeration of fecal Clostridium perfringens spores in egg yolk-free tryptose
      sulfite-cycloserine agar.
AB  - The Shahidi-Ferguson perfringens, tryptose-sulfite-cycloserine (TSC), and egg
      yolk-free TSC agars have been tested for their suitability to enumerate fecal
      spores of Clostridium perfringens. When these spores comprised at least 20% of
      the total anaerobe spores, equally accurate counts were obtained in the three
      media. With lower ratios of C. perfringens spores, the most accurate counts were
      obtained in egg yolk-free TSC agar. The median C. perfringens spore count of 60
      normal fecal specimens was log 3.4/g. A nonmotile, sulfite- and nitrate-reducing
      Clostridium, not identifiable with any known clostridial species, was isolated
      from 14 out of 60 fecal specimans. It was not differentiated from C. perfringens
      in the nitrite motility test, but could be distinguished by its inability to
      liquefy gelatin.

PMID- 4363370
TI  - The amino acid sequence of a protein (apovitellenin I) from the low-density
      lipoprotein of emu egg yolk.

PMID- 4363371
TI  - [Study of glucose-6-phosphatase in CC-14 poisoning].

PMID- 4363372
TI  - [Morphogenesis of optic path ways in the newborn rat: biochemical and
      morphological correlations].

PMID- 4363373
TI  - Editorial: The heart during sleep.

PMID- 4363375
TI  - Clinical pharmacology as an approach to the study of biochemical sleep
      mechanisms: the action of L-dopa.

PMID- 4363374
TI  - Pathology of murine cytomegalovirus infection in newborn mice. Muscle, heart, and
      brown fat lesions.
AB  - Newborn mice were inoculated intracerebrally with murine cytomegalovirus and
      studies were made of the pathological changes in the striate and cardiac muscle
      and brown fat. Widespread necrosis was seen in muscle and brown fat in the early
      stages of the infection. Necrotic lesions became calcified. By 56 days lesions
      were not resolved in the heart and brown fat but were completely resolved in
      skeletal muscle.

PMID- 4363376
TI  - Retarded growth of rats by anticonvulsant drugs.

PMID- 4363377
TI  - The polycyclic sleep-wake cycle in the cat: effects produced by sensorimotor
      rhythm conditioning.

PMID- 4363378
TI  - Asymptomatic infection with EB virus.
AB  - Evidence of asymptomatic EB virus infection was sought in healthy medical
      students and nurses following the observation that 1.4% possessed heterophile
      antibodies. The proportion of subjects with EB virus antibodies rose with age and
      there was evidence of recent infection in 19%. Smooth muscle antibodies were
      detected in 13 individuals and recent infection with EB virus was probable in six
      of these. Subclinical EB virus infections, in some cases associated with some
      disturbance of immunological function, may therefore be not uncommon in young
      adults.

PMID- 4363379
TI  - Investigation of the accompaniment of calcium during active calcium transport
      from human erythrocyte ghosts.
AB  - To determine whether a cell metabolite was involved in active calcium transport,
      the cell contents of human erythrocytes were subjected to high dilutions and the
      resultant ghosts were checked for their ability to actively transport calcium. It
      was found that the diluted erythrocyte ghosts did retain their capacity to
      actively transport calcium and that the characteristics of this transport process
      appeared to be unaltered by the high dilutions. Calcium analysis of the cell
      membrane and cell supernatant indicated that almost all of the calcium was lost
      from the cell solution rather than the cell membrane as active calcium transport
      proceeded. Therefore it appeared that calcium was able to cross the cell membrane
      without the aid of a cell metabolite. Investigations with layered erythrocytes
      indicated that the active transport of calcium was not assisted by
      centrifugation. Neither inorganic phosphate, pyrophosphate, nor an adenine
      nucleotide appeared to accompany calcium across the membrane as indicated by
      total phosphate and inorganic phosphate analysis and 260-nm readings of the
      deproteinized supernatant.

PMID- 4363380
TI  - A cyclic adenosine monophosphate link in the catecholamine enhancement of
      transmitter release at the neuromuscular junction.
AB  - The frequency of miniature endplate potentials (mepps) in rat diaphragms was
      markedly increased by epinephrine and norepinephrine in preparations exposed to
      15 mM K(+). The effect was rapid in onset but gradually declined during continued
      exposure to the catecholamines. N(6), O(2')-dibutyryl adenosine 3',5'
      monophosphate (dibutyryl-cAMP) also caused transient frequency increases
      resembling in time-course those observed with catecholamines. Contrary to
      previous reports, catecholamines and dibutyryl-cAMP had little effect on mepp
      frequency in preparations not treated with K(+). Sustained increases with
      theophylline and decreases with adenosine were found in both K(+)-treated and
      untreated preparations. Analysis of the data obtained with catecholamines showed
      the intensity of the response to be a function of nerve terminal polarization.
      The inability of catecholamines and dibutyryl-cAMP to affect mepp frequency of
      untreated preparations argues against an obligatory role for cAMP in the
      neurosecretory mechanism. The findings are consistent with an action of
      catecholamines and cAMP in the regulation of transmitter release at fatigued
      preparations.

PMID- 4363381
TI  - [Macula changes associated with pits in the optic disc (author's transl)].

PMID- 4363382
TI  - Metabolic effects of antibodies on platelets.

PMID- 4363383
TI  - Pulmonary generation and peripheral uptake of endogenous angiotensin II in man.

PMID- 4363384
TI  - Evidence that acromegaly is not a hypothalamic disease.

PMID- 4363385
TI  - Stimulation of adenosine 3',5'-cyclic monophosphate accumulation in anterior
      pituitary gland in vitro by purified growth hormone-releasing hormone.

PMID- 4363386
TI  - In vitro demonstration of normal thyrotropin (TSH) responsiveness in thyroid
      tissue from patients with Graves' disease.

PMID- 4363388
TI  - The Distinguished Lecture. The adrenal cortex: reflections, progress and
      speculations.

PMID- 4363387
TI  - Antifracture efficacy of long-term estrogens for osteoporosis.

PMID- 4363389
TI  - Cartilage collagen: substrate in soluble and fibrillar form for rheumatoid
      collagenase.

PMID- 4363390
TI  - [Etiology and epidemiology of oral carcinoma].

PMID- 4363391
TI  - [Desiccating factors in ulcerative necrotizing gingivitis].

PMID- 4363392
TI  - Development of chloroplasts in intact Atropa belladonna and in stem callus
      cultures during greening and leaf differentiation.

PMID- 4363393
TI  - Paneth cell metaplasia in diseases of the colon and rectum.

PMID- 4363394
TI  - Quantitative cytologic measurements in hepatomas.

PMID- 4363395
TI  - Complement-fixing antibodies against cytomegalovirus in different parts of the
      world.
AB  - A WHO cooperative study in which 27 laboratories participated showed that the
      distribution of cytomegalovirus antibodies in healthy blood donors varies widely,
      ranging from 40% in highly industrialized areas to 100% in developing countries.
      Climatic factors did not appear to play an important role in the spread of the
      virus.

PMID- 4363396
TI  - Ecological studies on Culex tritaeniorhynchus as a vector of Japanese
      encephalitis.
AB  - In the Republic of Korea, light-trap assessments and collections from cows and
      pigs after sunset were highly successful in monitoring the seasonal abundance of
      C. tritaeniorhynchus, the primary vector of Japanese encephalitis. The dates and
      duration of the population peaks at semirural suburbs of Seoul and Pusan were
      markedly different from those at a rural rice-growing site. The main breeding
      sites in these three areas were, respectively, swamps, marshes, and ricefields.
      The overall adult densities were the lowest at the rice-growing site where
      agricultural pesticides were extensively used. A short period of man-vector
      contact occurred at each study site at low densities when the natural population
      was at its peak. These vector monitoring techniques, coupled with information on
      antibodies in swine, represent a simple but valuable surveillance system.

PMID- 4363397
TI  - Immunity to cancer. Naturally occurring tumours in domestic animals as models for
      research. 1.
AB  - PREVENTIVE VACCINATION IS SUCCESSFULLY PRACTISED TODAY AGAINST TWO NEOPLASTIC
      DISEASES OF DOMESTIC ANIMALS: fibropapillomatosis of cattle and Marek's disease
      of chickens (a lymphoproliferative disease). Also it may soon be possible to
      immunize cats against lymphosarcoma. This memorandum describes these diseases and
      the immunological reactions involved. It also mentions a number of other tumours
      that could be used for immunological studies.The greatest advances in immunity
      have been made with the tumours caused by viruses. The killed papillomavirus
      vaccine used against bovine papillomatosis produces demonstrable antibodies
      against the virus. In the case of Marek's disease of chickens, which is due to a
      herpesvirus, a live virus vaccine is used. This does not prevent infection with
      virulent virus, but prevents the development of neoplasia. The mechanism by which
      the vaccine produces its effect is not yet known. Immunization with live and with
      killed vaccines has been successfully carried out experimentally against leukosis
      of chickens, which is caused by an oncornavirus. There is evidence that it will
      be possible to vaccinate cats against lymphosarcoma with non-living
      vaccine.Naturally occurring cancer in domestic animals parallels cancer in man
      more closely than does experimentally induced cancer in inbred laboratory
      animals; therefore immunological studies with the former are more likely to yield
      results relevant to the problem in man. Experimental cancer in rodents provides
      models that have the great advantages of uniformity and availability, and they
      cannot be replaced. However, models in domestic animals offer valuable
      supplementary systems for research aimed at elucidating the basic principles of
      immunity to cancer.

PMID- 4363398
TI  - Limitations of immunofluorescence tests in the diagnosis of infectious
      mononucleosis.
AB  - The relative value of heterophil agglutinins (HA) and of specific EBV antibodies
      in the diagnosis of infectious mononucleosis (IM) was assessed in 108 cases of
      the disease and in 280 controls. Among the 108 cases 93 were HA-positive by sheep
      cells in at least one of their sera, while 15 were HA-negative by the same test.
      Among the 280 controls false-positive HA tests were not encountered except in
      eight cases with the horse cell microtitre tests. With one of the two slide tests
      at least two false-positive tests and 12 false-negative tests were also found but
      these sera had low titres in microtitre tests. The HA life-span was found to be
      unexpectedly long in a few cases, sheep cell HA lasting up to 8 to 10 months and
      horse cell HA up to 21 to 23 months.Many false-positive tests may therefore not
      be true false-positives and may result from the persistence of HA following
      unrecognized mononucleosis months before. Virtually all cases of IM had (or
      developed) antibodies to Epstein-Barr virus, viral capsid antigen (EBV-VCA),
      whereas only half of the controls were EBV-VCA-positive. The comparative analysis
      of nonspecific and specific test results in mononucleosis allows the following
      conclusions: (1) horse cell microtitre tests and the monospot test are more
      sensitive than sheep cell microtitre tests and the monotest; (2) false-negative
      results are occasionally seen with the latter tests but not with the former; (3)
      more false-positive results, however, are probably seen with the former tests;
      and (4) specific EBV-IgM and EBV-EA antibody tests are useful in the diagnosis of
      selected borderline cases of mononucleosis.

PMID- 4363399
TI  - Parathyroid carcinoma: location of pelvic metastases by parathyroid hormone
      assay.
AB  - A metastasis from a functioning parathyroid carcinoma was located by PTH
      radioimmunoassay and selective venous catheterization. The site of the
      metastasis, verified at autopsy, was in the right side of the pelvis. This is the
      most distant reported location for metastatic parathyroid carcinoma. The
      patient's plasma immunoreactive PTH rose more than twofold in response to induced
      hypocalcemia. This suggests that relative hypocalcemia, induced therapeutically
      in such patients, may result in a higher chronic level of PTH secretion.

PMID- 4363400
TI  - [Autopsy case of monocytic leukemia with severe peripheral nerve disturbance].

PMID- 4363402
TI  - Address to Annual Meeting of the American Medical Women's Association.

PMID- 4363401
TI  - [4,4'-Diaminodiphenylmethane--histological, enzyme histochemical and
      autoradiographic investigations in acute and subacute experiments in rats, with
      and without the additional stress of heat (author's transl)].

PMID- 4363403
TI  - Success or failure: women as medical school applicants.

PMID- 4363404
TI  - Sex ratios in authorship and acknowledgments for medical journal articles.

PMID- 4363405
TI  - An internal auditing system for improving the quality of medical care.

PMID- 4363407
TI  - The effect of cyclic AMP and dibutyryl cyclic AMP on the permeability
      characteristics of the renal tubule.
AB  - The effect of adenosine-3',5'-cyclic monophosphate (cyclic AMP) and N(6),O(2)
      dibutyryl adenosine-3',5'-cyclic monophosphate (dibutyryl cyclic AMP) on renal
      tubular permeability was studied by microinjection techniques in anesthetized
      diuretic rats. Radioactive inulin and mannitol were microinjected simultaneously
      into superficial proximal and distal convolutions and recovery of the isotopes
      was measured in the urine.During control conditions, mannitol and inulin recovery
      was essentially complete. However, during infusion of cyclic AMP or dibutyryl
      cyclic AMP, mannitol recovery was significantly less than control after early
      proximal and late proximal microinjections, averaging 79 and 85%, respectively.
      There was no loss of mannitol from the nephron after microinjection into distal
      convolutions. Inulin recovery was complete after all microinjections during
      cyclic AMP or dibutyryl cyclic AMP infusion. Simultaneous clearances of mannitol
      and inulin as well as peritubular capillary microinjections studies demonstrated
      bidirectional fluxes of mannitol across the proximal tubular epithelium during
      infusion of cyclic AMP or dibutyryl cyclic AMP. Intratubular pressures were not
      different during control and experimental periods. These studies demonstrate a
      change in the permeability characteristic of the proximal convoluted tubule
      during infusion of cyclic AMP and dibutyryl cyclic AMP. This change in
      permeability of the proximal tubule could account for the effects of cyclic AMP
      on proximal tubular transport processes.

PMID- 4363406
TI  - Familial hypercholesterolemia (one form of familial type II
      hyperlipoproteinemia). A study of its biochemical, genetic and clinical
      presentation in childhood.
AB  - Primary hyperbetalipoproteinemia (type II hyperlipoproteinemia) is a common
      disorder associated with premature vascular disease. It is frequently due to
      genetic abnormalities, some of which are expressed in childhood. We have examined
      the manner in which that form of hyperbetalipoproteinemia known as familial
      hypercholesterolemia may be expressed in 236 children aged 1-19 born of 90
      matings in which one parent had hyperbetalipoproteinemia of this variety and one
      parent did not.Two Gaussian populations were fitted to the distribution of both
      low density lipoprotein cholesterol (C(LDL)) and plasma cholesterol (C) in these
      children and a likelihood ratio test strongly favored a two over a one population
      model for both C(LDL) (X(2) = 18.41, P < 0.0005) and C (X(2) = 7.81, P < 0.025).
      45% of the children were in the population identified as affected; their mean
      C(LDL) was 229. The remaining 55% were in the normal population with a mean
      C(LDL) of 110 which was indistinguishable from that of an unrelated control
      population, aged 1-19. On the basis of an assumed frequency of
      hyperbetalipoproteinemia in the general population of 5%, the Edwards' test
      indicated that a polygenic model of inheritance was highly unlikely (expected,
      22%; observed, 45%). The segregation ratio obtained from the derived intersection
      between the two population curves (C(LDL), 164 mg/100 ml; C, 235 mg/100 ml) was
      45/55 (abnormal/normal). The percentage of abnormal children in the first decade
      (52%) significantly exceeded that in the second (39%) (P < 0.01). The ratios
      (II/N) were 50/47 and 55/84 in the offspring of affected female and male parents,
      respectively (X(2) = 3.819, 0.05 < P < 0.10). Only 10% of
      hyperbetalipoproteinemic children were considered to have hyperglyceridemia.
      These children, frequently, but not invariably, had a parent with
      hyperglyceridemia in addition to hyperbetalipoproteinemia (P < 0.05). None of the
      affected children who were examined had ischemic heart disease (IHD) and 7% had
      tendon xanthomas. Half of the parents (mean age, 37.4 yr) who were examined had
      IHD and three-quarters had xanthomas. The data agree well with the hypothesis
      that hyperbetalipoproteinemia is inherited as a monogenic trait with early
      expression in these children. More than one genetic defect within the group is
      not excluded, but retrospective analyses of the 345 first-degree adult relatives
      of the affected parents indicated that most of the abnormal parents probably
      represented familial hypercholesterolemia, rather than combined hyperlipidemia,
      the other most generally recognized form of familial hyperbetalipoproteinemia.

PMID- 4363408
TI  - Assay of total plasma apolipoprotein B concentration in human subjects.
AB  - We have developed a double antibody radioimmunoassay (RIA) for human
      apolipoprotein B (ApoB). The assay measures not only the ApoB content of beta
      lipoproteins (low density lipoproteins [LDL]) but also that contained in the
      other lipoproteins in plasma. Purified lymph and plasma chylomicrons and plasma
      very low density lipoproteins (VLDL) produced displacement curves in the assay
      system which paralleled those produced by pure LDL. Thus, the ApoB found in
      chylomicrons, VLDL, and LDL were immunologically identical. ApoB accounted for
      about 25 and 35%, respectively, of the total protein of chylomicrons and VLDL by
      RIA. VLDL and LDL preparations from normal and hyperlipoproteinemic subjects also
      produced parallel displacement curves, suggesting that the ApoB of normal and
      hyperlipoproteinemic subjects were immunologically identical. High density
      lipoproteins and abetalipoproteinemic plasma displaced no counts, nor did the
      sera of several animal species produce any useful displacement curves in this
      system. The fasting total plasma ApoB concentration of normal subjects was 83+/
      16 mg/dl (mean+/-SD). ApoB levels were high in Type II (162+/-16), and less so in
      Type IV (112+/-24) and Type V (105+/-17).When plasma ApoB concentration in Type
      IV patients was graphed against plasma glycerides, two subpopulations, which may
      represent different genetic or biochemical subgroups, were apparent.ApoB
      concentration in individuals on constant diet and drug regimen was stable over
      weeks to months. Greater than 90% of ApoB of normal and Type II subjects was in
      the d > 1.006 plasma fraction. By contrast, only 50-80% of ApoB was in the d >
      1.006 fraction in Types IV and V. Thus, hypertriglyceridemia was associated
      primarily with a redistribution of ApoB to the lighter density fractions; by
      contrast, in hypercholesterolemia absolute ApoB concentration was markedly
      increased.

PMID- 4363410
TI  - Concordant segregation of the expression of SV40 T antigen and human chromosome 7
      in mouse-human hybrid subclones.
AB  - Subcloning of Simian virus 40 (SV40) T antigen-positive mouse-human hybrids,
      derived from the fusion of mouse cells deficient in thymidine kinase with SV40
      transformed Lesch Nyhan fibroblasts, resulted in their segregation into T antigen
      positive and negative subclones. Positive correlation between the presence of
      human chromosome 7 and the expression of SV40 T antigen was established in the
      subclones examined. These results negate the possibility of a transfer of the
      SV40 genome to a mouse chromosome.

PMID- 4363409
TI  - Epstein-barr virus-negative human malignant T-cell lines.
AB  - Two lymphoblastoid lines, CCRF-CEM and HSB-2, with properties of malignant cells,
      derived from children with leukemia secondary to lymphosarcoma, have T-cell
      properties and lack Epstein-Barr virus antigens.

PMID- 4363411
TI  - [Healthy living through correct nutrition].

PMID- 4363412
TI  - [Nutrition in childhood].

PMID- 4363413
TI  - [Nutritional status in old age].

PMID- 4363414
TI  - [High quality health care for large communities].

PMID- 4363415
TI  - [Proposals for weight reducing. Significance and causes of obesity].

PMID- 4363416
TI  - [Vitamins are preventative].

PMID- 4363418
TI  - [Anesthesia and intensive care. IV. Diagnostic and therapeutic nerve blocks].

PMID- 4363417
TI  - [Nutrition of patients with skull-brain injuries].

PMID- 4363419
TI  - [Where are the professionals?].

PMID- 4363420
TI  - [Role of cyclic AMP in coronary circulation].

PMID- 4363421
TI  - Aldosterone: current concepts.

PMID- 4363422
TI  - [Use of a model for study of the interactions of 2 substances in fish
      toxicology].

PMID- 4363423
TI  - [Preservation soil for C1.perfringens].

PMID- 4363424
TI  - Wilm's tumor: thirty-year review of cases in Buffalo.

PMID- 4363425
TI  - [Role of local immunity in the resistance against respiratory viral infections].

PMID- 4363426
TI  - [The cyclic adenylcyclase AMP system as a modulator of thyroid homeostasis.
      Physiopathological and clinical implications].

PMID- 4363427
TI  - [Various recent uses of hormones and their mechanism of action on the cell
      level].

PMID- 4363429
TI  - Timing of interceptive orthodontic measures based on stages of maturation.

PMID- 4363428
TI  - Increased production of cyclic AMP in mechanically stressed alveolar bone in
      cats.

PMID- 4363431
TI  - Hereditary deafness in the white cat.

PMID- 4363432
TI  - Immunoprecipitation is inappropriate for the isolation of radiochemically pure
      albumin from tissues.

PMID- 4363433
TI  - A method for isolating respiring mitochondria from epiphyseal cartilage.

PMID- 4363434
TI  - A method for separating DNA fragments by electrophoresis in polyacrylamide
      concentration gradient slab gels.

PMID- 4363435
TI  - Determination of 2,4-dihydroxy-1,4(2h)-benzoxazin-3-one glucosides in corn (Zea
      mays L.).

PMID- 4363436
TI  - Rapid sampling of yeast cells and automated assays of adenylate, citrate,
      pyruvate and glucose-6-phosphate pools.

PMID- 4363437
TI  - A high precision fluorometer for biochemical measurements.

PMID- 4363438
TI  - Adsorption chromatography of cyclic nucleotides on silica gel and alumina thin
      layer sheets.

PMID- 4363439
TI  - Assay for the enzymic hydrolysis of penicillin and acylhydroxamates.

PMID- 4363441
TI  - Separation of proteins by high-speed pressure liquid chromatography.

PMID- 4363442
TI  - Enzymatic synthesis of 32P-labeled coenzyme A.

PMID- 4363440
TI  - Microanalytical determination of the activities of phospholipases A, C, and D and
      of their mixtures.

PMID- 4363443
TI  - Percentage recovery of free fatty acids from bovine muscle lipids by
      nonchromatographic techniques.

PMID- 4363444
TI  - Antigenic structure of murine mammary tumour viruses.

PMID- 4363445
TI  - The lack of effect of mouse epidermal growth factor (EGF) and its anti-serum on
      human tissues.

PMID- 4363447
TI  - Spin concentration per living cell of normal liver, regenerating liver, and
      hepatomas.

PMID- 4363446
TI  - Carcinogenic effect of N-nitrosoamines related to butyl(4
      hydroxybutyl)nitrosoamine in ACI-N rats, with special reference to induction of
      urinary bladder tumors.

PMID- 4363448
TI  - [Advances in cytochemical differentiation of cellular infiltrates into the skin].

PMID- 4363449
TI  - [Clinical aspects, storage capacity and epidermal changes in histiocytomas].

PMID- 4363450
TI  - The evolution of a state hospital into a human-services center.

PMID- 4363451
TI  - The impact of a mental health center on admissions to a state hospital system.

PMID- 4363452
TI  - On the mechanism of thymine formation from thymine glycol by gamma-irradiation in
      aqueous system.

PMID- 4363453
TI  - Ultrastructure of inclusion bodies in type II cells of lung, human and sub
      simian.

PMID- 4363454
TI  - The velocity of lymph flow in the canine thoracic duct.
AB  - 1. The velocity and pattern of movement of lymph in the thoracic duct of
      anaesthetized and conscious dogs has been studied by observing the movement of
      droplets of ultrafluid lipiodol in the duct.2. The velocity of flow when
      anaesthetized varied from 0.1-2.0 cm/sec, to 5.0 cm/sec when conscious.3. The
      pattern of flow was affected by respiration and the cardiac cycle. Most movement
      occurred at the end of inspiration.4. The duct of five autopsy preparations was
      perfused with saline to assess the volume and velocity of flow produced by the
      level of pressure gradients previously observed in the duct. These studies show
      that the small gradients (2-5 mmHg) observed during life are more than sufficient
      to produce the normal volume and velocity of flow measured. The mean resistance
      of the duct was 0.5 mmHg/ml. min.

PMID- 4363455
TI  - Analysis of the role of cyclic adenosine 3',5'-monophosphate in catecholamine
      release.
AB  - 1. Cyclic adenosine 3',5'-monophosphate (cyclic AMP) levels and catecholamine
      release were measured in cat adrenal glands perfused in situ with Locke
      solution.2. Cyclic AMP was present in the medulla in an amount which represented
      approximately one fifth of that present in the cortex.3. Perfusion with
      acetylcholine (ACh) or nicotine increased cyclic AMP both in the intact adrenal
      and in the perfusate. The time course of the changes in tissue cyclic AMP during
      stimulation was out of phase with the time course of catecholamine release.
      Maximal increases in cyclic AMP were not manifest until after 8 min of exposure
      to the secretogogue, whereas maximal rates of secretion occurred during the first
      minute.4. Theophylline (0.5 mM) increased basal and stimulated adrenal cyclic AMP
      levels, but did not potentiate the secretory response to ACh or nicotine.5.
      Perfusion with cyclic AMP or its dibutyryl derivative (0.2-4 mM) failed to effect
      a consistent or significant increase in the rate of catecholamine release and was
      unable to potentiate the secretory response to a submaximal concentration of ACh
      or calcium.6. The results suggest that, unlike calcium, cyclic AMP is not a
      direct mediator of medullary secretion.

PMID- 4363456
TI  - Plasma renin and angiotensin II in conscious pregnant ewes and their lambs.

PMID- 4363457
TI  - Negative feed-back regulation of noradrenaline release by nerve stimulation in
      the perfused cat's spleen: differences in potency of phenoxybenzamine in blocking
      the pre- and post-synaptic adrenergic receptors.
AB  - 1. The effects of low concentrations of phenoxybenzamine (8.8 x 10(-10) to 2.9 x
      10(-7)M) on responses and on noradrenaline overflow elicited by nerve stimulation
      were studied in the perfused cat's spleen.2. In the presence of 8.8 x 10(-10)M or
      2.9 x 10(-9)M phenoxybenzamine there was a significant reduction in responses to
      nerve stimulation while the overflow of the transmitter did not increase at the
      two frequencies of stimulation employed: 5 and 30 Hz.3. In the presence of 2.9 x
      10(-8)M or 2.9 x 10(-7)M phenoxybenzamine the responses to nerve stimulation were
      practically abolished and a significant increase in transmitter overflow was
      obtained at both frequencies of stimulation. The drug was more effective in
      increasing transmitter overflow at 5 Hz when compared with 30 Hz.4. The higher
      effectiveness of phenoxybenzamine in blocking the post-synaptic alpha-receptor
      when compared with the blockade of the presynaptic alpha-receptor that regulates
      transmitter release is compatible with the view that these two receptors are not
      identical.5. A second alternative for the difference in effectiveness of
      phenoxybenzamine is that both types of alpha receptors are identical, but the
      spare receptor capacity for the presynaptic adrenergic receptors is higher than
      that of the post-synaptic receptors.

PMID- 4363458
TI  - Gamma-aminobutyric acid and inhibition in the septal nuclei of the rat.
AB  - 1. The electrophoretic application of gamma-aminobutyrate (GABA) and glycine to
      septal neurones inhibited their discharge, but the currents required to cause
      equivalent degrees of inhibition were always smaller for GABA than for glycine.2.
      The actions of GABA but not those of glycine were antagonized by bicuculline and
      not by strychnine and vice versa.3. The recurrent collateral inhibition of
      lateral septal neurones and the direct inhibition of medial cells evoked by
      stimulation of the fimbria were blocked by bicuculline but not by strychnine.4.
      The bursting patterns of discharge of laterally situated medial septal neurones
      was disrupted by bicuculline, but required a longer application of the drug than
      was needed to block the direct fimbrial inhibition. It is suggested that this
      disruption is due to diffusion of the drug to affect the inhibitory interneurones
      of the lateral septum.5. It is concluded that the inhibitory processes in the
      septum involve GABA as the synaptic transmitter.

PMID- 4363459
TI  - [A case of benign pelomorphic adenoma orginated from a minor salivary gland of
      the right buccal mucosa (author's transl)].

PMID- 4363460
TI  - [Current views on the viral origin of cancer].

PMID- 4363461
TI  - Cell fusion induced by pederine.

PMID- 4363462
TI  - The preparation of single cell suspensions from liver and their use for the study
      of protein synthesis.

PMID- 4363463
TI  - Repeated partial endoscopic resections as treatment for two patients with
      inoperable tracheal tumours.

PMID- 4363464
TI  - [Investigations concerning the incidence of disorders of lipid and carbohydrate
      metabolism in primary gout and symptomless hyperuricaemia (author's transl)].

PMID- 4363465
TI  - [German measles and cytomegalic virus disease contamination of the female
      population].

PMID- 4363466
TI  - Prophylaxis of endemic goitre.

PMID- 4363467
TI  - Five years follow-up in the treatment of endemic goiter by iodized oil.

PMID- 4363468
TI  - Biochemical studies on endemic goiter glands before and one year after an
      injection of iodized oil.

PMID- 4363469
TI  - Factors which may alter the epidemiology of endemic goiter.

PMID- 4363470
TI  - Gonadotropins and ovarian function.

PMID- 4363471
TI  - Clinical implications of monoclonal gammopathy in chronic liver disease.

PMID- 4363473
TI  - Cytomegalovirus and renal vein thrombosis in a newborn infant.

PMID- 4363474
TI  - Bordetella pertussis serotypes in a whooping cough outbreak.

PMID- 4363472
TI  - Direct effects of alcohol on in vivo and in vitro exocrine pancreatic secretion
      and metabolism.

PMID- 4363475
TI  - Metabolic defects of primary hyperuricemia and gout.

PMID- 4363476
TI  - Disseminated herpes with hepatoadrenal necrosis in an adult.

PMID- 4363478
TI  - Virus-induced diabetes mellitus. II. Relationship between beta cell damage and
      hyperglycemia in mice infected with encephalomyocarditis virus.
AB  - Infection of DBA 2 male mice with the M variant of encephalomyocarditis virus
      resulted in a diabetes-like syndrome. Histologic examination of the pancreas
      revealed damage to the beta cells with little involvement of the acinar cells.
      The severity of the hyperglycemia correlated closely with the degree of beta cell
      damage. By immunofluorescence, viral antigens could be detected in the beta cells
      during the first 10 days of the infection. In contrast to the response found in
      male DBA 2 mice, infection of DBA 2 female mice and male mice of several other
      strains resulted in little if any elevation of blood glucose concentration.
      Histologic examination of the pancreas of these animals revealed only minimal
      damage to the beta cells. It is concluded that differences in the severity of the
      hyperglycemia between DBA 2 males and females and among the different strains of
      male mice tested are directly related to the degree of beta cell damage produced
      by the viral infection.

PMID- 4363479
TI  - Pathology of colonic polyps as it relates to surgical management.

PMID- 4363477
TI  - Neurotropic virus-host relationship alterations due to variation in viral genome
      as studied by electron microscopy.
AB  - A series of experiments has been described in which litters of suckling rats were
      inoculated either with wild-type reovirus type III or one of two of its
      temperature-sensitive (ts) mutants. While the wild-type virus produced an acute,
      fatal syndrome, the ts mutants were substantially less neurovirulent. Of the ts
      mutant-inoculated animals, a large percentage of the surviving (chronic) animals
      given ts mutant B showed an unobstructive hydrocephalus ex vacuo whereas chronic
      ts mutant C animals showed no visible nervous system disease. The ts mutants
      persisted within the central nervous system (CNS) for 6 to 8 weeks, after which
      they could not be detected either virologically, immunologically or
      morphologically. In another set of experiments, organized CNS explants were
      studied following infection with either measles virus or the neuroadapted
      Mantooth strain of SSPE virus, a variant of measles. Wild measles (Edmonston
      strain) exerted an acute destructive effect, but SSPE virus had a tendency to
      enter into coexistence with the tissue without destroying its organotypic nature.
      These relationships are somewhat reminiscent of the neuropathologic conditions
      caused by these two viruses in man. Since the reovirus type III ts mutants
      possess both genetic and morphologic defects and in many instances cause CNS
      conditions different from that induced by the wild-type virus, it has been
      proposed that a comparable situation may exist after measles and SSPE virus
      infection. SSPE virions of the strain studied were found to be defective in
      certain viral components which may have contributed to the lower neurovirulence
      and its entering into a chronic relationship with the CNS, in contrast to the
      acute destructive nature of measles infection. The findings are discussed in
      terms of relevance to other chronic CNS diseases, particularly multiple
      sclerosis, in which the possiblity exists that a mutant virus is operative.

PMID- 4363480
TI  - A comparison of the interlaboratory reproducibility of the Hansen
      radioimmunoassay for carcinoembryonic antigen.

PMID- 4363481
TI  - The diagnosis of malignant neoplasms in infants and children.

PMID- 4363482
TI  - Catecholamine measurements in pheochromocytoma and neuroblastoma.

PMID- 4363484
TI  - Initial steps in the degradation of n-alkane-1-sulphonates by Pseudomonas.

PMID- 4363483
TI  - Selection and characterization of acriflavine-induced mutants of Candida
      albicans.

PMID- 4363485
TI  - Pathways of glycollate metabolism in the blue-green alga Anabaena cylindrica.

PMID- 4363487
TI  - IV. Joint erosion in rheumatoid arthritis.

PMID- 4363486
TI  - Editorial: The compensated polarized light microscope in clinical rheumatology.

PMID- 4363488
TI  - Proceedings: Lymphocyte tubuloreticular structures--disease activity correlation
      and sequential studies in systemic lupus erythematosus.

PMID- 4363489
TI  - Proceedings: New and simple polarized microscopy.

PMID- 4363490
TI  - Subcellular fractionation of rat cerebellum: an electron microscopic and
      biochemical investigation. II. Resolution of morphologically characterised
      fractions.

PMID- 4363491
TI  - The effect of high doses of synthetic ACTH on rat brain.

PMID- 4363492
TI  - Corticosterone binding to hippocampus: immediate and delayed influences of the
      absence of adrenal secretion.

PMID- 4363493
TI  - Androgen-induced enhancement of vascular reactivity.

PMID- 4363494
TI  - Role of the N-terminal amino acid for the biological activities of angiotensin
      and inhibitory analogues.

PMID- 4363495
TI  - Action of angiotensin and analogues on the heart.

PMID- 4363496
TI  - The effect of replacement of potassium by cesium ions on neuromuscular blockade
      of the rat phrenic nerve--diaphragm preparation in vitro.

PMID- 4363497
TI  - Constancy and linearity of the metabolic clearance of adrenocorticotropin in
      dogs.

PMID- 4363499
TI  - The insulin-glucose ration in children with islet cell tumors of the pancreas.

PMID- 4363498
TI  - Renin activity by radioimmunoassay: the plasma incubation step.

PMID- 4363500
TI  - Germ cell tumors of the ovary: the role of pathology in diagnosis and management.

PMID- 4363501
TI  - Gestational trophoblastic neoplasia.

PMID- 4363502
TI  - Physical biochemistry of calcification.

PMID- 4363503
TI  - Batrachotoxin, an extremely active cardio- and neurotoxin from the Colombian
      arrow poison frog Phyllobates aurotaenia.

PMID- 4363504
TI  - Biochemistry of iron.

PMID- 4363505
TI  - Intracellular recording of spontaneous local responses in the chronic
      epileptogenic focus of a rhesus monkey.

PMID- 4363506
TI  - [Treatment and after-treatment of carcinoma in the female. 1st Oberaudorf
      discussion, 24-26 October 1973].

PMID- 4363507
TI  - Editorial: Status report: feline leukemia.

PMID- 4363508
TI  - Preparation and use of soluble ferritin-antiferritin complexes as a specific
      marker for immunoelectron microscopy.

PMID- 4363509
TI  - Enzymatic digestion of the first component of human complement (C1q).

PMID- 4363510
TI  - Abnormalities in the mixed leukocyte reaction during infectious mononucleosis.

PMID- 4363511
TI  - Wilms' tumor in the horseshoe kidney.

PMID- 4363512
TI  - 3H-actinomycin D binding to DNA localized in ultrathin sections of plastic
      embedded biological materials.

PMID- 4363514
TI  - Staining methods of Australia antigen in paraffin section--detection of
      cytoplasmic inclusion bodies.

PMID- 4363513
TI  - Comparison of red cell angiotensinase activity in man and animals.

PMID- 4363515
TI  - Effect of mitotic inhibitors on C-type virion production.

PMID- 4363516
TI  - Toxic metabolites released from rat hepatoma cells in culture. 2. Biological and
      chemical analyses of toxic metabolites.

PMID- 4363517
TI  - Endothelial injury and platelet aggregation assoicated with acute lipid
      mobilization.

PMID- 4363518
TI  - Experimental hydrocephalus: surface alterations of the lateral ventricle.
      Scanning electron microscopic studies.

PMID- 4363519
TI  - Oncorna virus disease. The syndrome of hemolytic anemia and lymph node cystic
      disease.

PMID- 4363520
TI  - Effect of prophylactic measures on the microbial flora of patients in protected
      environment units.

PMID- 4363521
TI  - Studies of resonance energy migration in a heterogeneous pigment complex. I.
      Heterogeneity as a factor accelerating the localization of electron excitation in
      traps.

PMID- 4363522
TI  - Conformational changes in spin-labeled antibodies and antigens during specific
      complex formation.

PMID- 4363523
TI  - Letter: Adrenal responsiveness in chronic hemodialysis.

PMID- 4363524
TI  - Letter: Neuropathy and methyl N-butyl ketone.

PMID- 4363525
TI  - Letter: Mechanisms of lithium action.

PMID- 4363526
TI  - [Facilitation of cortical neuronal reactions to cortical and peripheral
      stimulation following tetanization of the surface of the brain].

PMID- 4363527
TI  - [Corticofugal postsynaptic influences on red nucleus neurons].

PMID- 4363528
TI  - [Synaptic potentials of the motor neurons of the digastric muscle].

PMID- 4363530
TI  - [The nature of the electrical responses of fish retina horizontal cells].

PMID- 4363529
TI  - [The influence of forelimb afferents on the activity of motor neurons in the
      lumbar region of the spinal cord].

PMID- 4363531
TI  - [Characteristics of the electrical reactions of the medial geniculate bodies of
      flat-nosed and horseshoe-nosed bats to ultrasound stimuli of different frequency
      ranges].

PMID- 4363532
TI  - [The slow negative wave of the evoked potential of the frog midbrain tectum].

PMID- 4363534
TI  - [Rubrospinal synaptic influences on the lumbar motor neurons of rats].

PMID- 4363533
TI  - [The neuronal organization of the dentate nucleus of the cerebellum].

PMID- 4363535
TI  - [Centrifugal influences on the amacrine cells of the frog retina].

PMID- 4363536
TI  - Leptomeningeal changes following lumbar myelography with water-soluble contrast
      media (meglumine iothalamate and methiodal sodium).

PMID- 4363537
TI  - A landmark for the choroidal arteries of the fourth ventricle--branches of the
      posterior inferior cerebellar artery.

PMID- 4363538
TI  - Studies of chicken sarcoma (strain 13). A review.

PMID- 4363539
TI  - Interdependable effects of magnesium ion and ethylene diamine tetracetate (EDTA)
      on chicken liver D-fructose-1,6-diphosphate, 1-phosphohydrolase.

PMID- 4363540
TI  - Effect of various nucleoside triphosphates on the catalytic activity of chicken
      liver fructose diphosphatases.

PMID- 4363541
TI  - [Amino acid dehydrogenases of Candida albicans at different growth periods].

PMID- 4363542
TI  - [Current problems of solid tumors in childhood].

PMID- 4363544
TI  - [Indications for radiotherapy alone or combined with chemotherapy in solid tumors
      of the child].

PMID- 4363545
TI  - [Testicular tumors in childhood].

PMID- 4363543
TI  - [Biochemical tumor diagnosis in childhood].

PMID- 4363546
TI  - [Wilms' tumor in the newborn infant. Statistics and results of follow-up
      studies].

PMID- 4363547
TI  - [Behavior of peripheral estrogen receptors during clomiphene therapy].

PMID- 4363548
TI  - [Glucocorticoid and androgenic function of the adrenal cortex in lumbosacral
      radiculitis before and after hydrocortisone treatment].

PMID- 4363550
TI  - [Etiology of leukemias: role of virus in leukemogenesis (author's transl)].

PMID- 4363549
TI  - Ultrastructure of hepatoma cells detected in peritoneal fluid.

PMID- 4363551
TI  - Haptoglobin levels in the plasma of newborn infants with special reference to
      infections.

PMID- 4363552
TI  - Common bile duct obstruction by granular cell tumor (schwannoma).

PMID- 4363553
TI  - Hepatoma, erythrocytosis and increased serum erythropoietin developing in long
      standing hemochromatosis.

PMID- 4363554
TI  - The history of infectious mononucleosis.

PMID- 4363555
TI  - Relationship of cellular fatty acid composition to survival of Lactobacillus
      bulgaricus in liquid nitrogen.
AB  - Concentrated cultures of Lactobacillus bulgaricus were prepared by resuspending
      cells grown in semisynthetic media in sterile 10% non-fat milk solids. The
      concentrated cultures were frozen in liquid nitrogen for 24 h. The cell
      suspensions exhibited decreased viability after storage, and the amount of death
      varied among the different strains tested. Storage stability of all strains
      examined was improved by supplementing the growth medium with sodium oleate.
      Radioisotopes were used to study the fate of sodium oleate with L. bulgaricus
      NCS1. [1-(14)C]sodium oleate was incorporated solely into the lipid portion of
      the cells, including both neutral and polar lipids. The fatty acid composition of
      L. bulgaricus NCS1, NCS2, NCS3, and NCS4 grown with and without sodium oleate was
      studied. The major fatty acids of strains NCS1, NCS2, and NCS3 grown without
      sodium oleate were dodecanoic, tetradecanoic, hexadecanoic, hexadecenoic, and
      octadecenoic acids. In addition to these, strain NCS4 contained C(19)
      cyclopropane fatty acid. The major fatty acids of all strains grown with sodium
      oleate were tetradecanoic, hexadecanoic, hexadecenoic, octadecenoic, and C(19)
      cyclopropane fatty acids. All strains grown in broth containing sodium oleate
      contained larger amounts of octadecenoic and C(19) cyclopropane fatty acid, and
      less saturated fatty acids than when grown without sodium oleate. Statistical
      analyses indicated that C(19) cyclopropane fatty acid was most closely related to
      stability of the lactobacilli in liquid nitrogen. A negative regression line that
      was significant at P < 0.001 was obtained when the cellular content of this fatty
      acid was plotted against death.

PMID- 4363556
TI  - Phosphatase activity of anaerobic organisms.
AB  - Anaerobic organisms were tested for phosphatase activity in different pH ranges.
      Several groups of organisms displayed characteristic patterns. Bacteroides
      fragilis, B. melaninogenicus, and B. ruminicola produced phosphatase with
      strongest activity at pH 8.6. Fusobacterium mortiferum was the only species of
      this genus to show strong hydrolysis. The enzyme was active in both acid and
      alkaline ranges. The activity of gram-positive organisms was variable, the most
      active groups being Clostridium perfringens, Peptostreptococcus intermedius, P.
      micros, and Peptococcus constellatus. The incorporation of phosphatase activity
      into the identification scheme of anaerobes seems feasible. There was a
      correlation of hydrolysis with several important pathogens.

PMID- 4363557
TI  - Specificity and sensitivity of the streptozyme test for the detection of
      streptococcal antibodies.
AB  - A comparison between the results of the streptozyme hemagglutination test and
      serological titers for anti-streptolysin O (ASO), anti-hyaluronidase (AH), anti
      deoxyribonuclease B (ADN-B), and anti-nicotinamide adenine dinucleotidase (ANAD)
      was made in two groups of human sera. In one group, serological titers for all
      the four antibodies were lower than the threshold of sensitization reported by
      the producing firm. In the second group, the titer of at least one of the four
      antibodies was equal to or higher than the threshold. False-positive and false
      negative reactions occur with those sera when one or more antibody titer is at or
      near the threshold of the test as described by the manufacturer. The test was
      positive for all sera where either the ASO was greater than 166 or the ANAD was
      greater than 270, and for 98% of the sera with ADN-B greater than 360. It is,
      therefore, concluded that the streptozyme test can be used as an adjunct to the
      clinical diagnosis of streptococcal infections and their nonsuppurative sequelae.
      It is less useful to assess the levels of antibodies in sera from general
      population surveys. For such sera, the relative specificity and sensitivity of
      the test might yield misleading results. Until more experience is gained with the
      test, caution should be used in its application to infant and older adult age
      groups, where significant streptococcal antibody titers are frequently near the
      threshold of the test.

PMID- 4363558
TI  - Evaluation of media, time and temperature of incubation, and method of
      enumeration of several strains fo Clostridium perfringens spores.
AB  - Two basal media, containing the ingredients found in common in both SPS (BBL) and
      TSN (BBL) media and in the previously described media of Schaedler et al. (1965)
      and Starr et al (1971), but minus antibiotics, were selected as the most suitable
      for the enumeration of Clostridium perfringens spores in a model system. These
      media were also used to study the influence of the presence of glucose, xylose,
      or ribose in various concentrations (0, 0.01, 0.1, and 1.0%) on colony morphology
      and spore recovery. As the sugar concentration in the basal agar medium
      increased, the colonies of all the test organisms also increased in size, and
      more of the black colonies became white in color. At the 1.0% sugar level,
      glucose permitted only white colony development, whereas the pentoses were
      completely inhibitory. Both pour plates and most-probable-number tubes were
      inoculated with the spores of several strains of C. perfringens and incubated at
      20, 30, 37, and 45 C for 24, 48, and 72 h. Statistical analyses of the
      enumeration data indicated, at the 99% confidence level, that a Trypticase(BBL)
      yeast extract-glucose-sulfite-iron agar gave maximal population estimates at 37 C
      in 72 h.

PMID- 4363559
TI  - Requirement for and sensitivity to lysozyme by Clostridium perfringens spores
      heated at ultrahigh temperatures.
AB  - The requirement of ultrahigh temperature (UHT)-treated Clostridium perfringens
      spores for lysozyme and the sensitivity of heated and unheated spores to lysozyme
      were studied. The UHT-treated spores requiring lysozyme for germination and
      colony formation originated from only a small portion of the non-UHT-treated
      spore population. This raised a question of whether the requirement for lysozyme
      was natural to the spores or was induced by the UHT treatments. However, these
      spores did not require lysozyme for germination before UHT treatment, which
      confirmed that the requirement for lysozyme had been induced by the UHT
      treatment. Only 1 to 2% of the spores were naturally sensitive to lysozyme;
      therefore, the mere addition of lysozyme to the plating medium did not permit the
      enumeration of all survivors. Treatment of UHT-treated spores with
      ethylenediaminetetraacetate (EDTA) sensitized the spores to lysozyme and
      increased by 10- to 100-fold the number of survivors that were detected on a
      medium containing lysozyme. Under the heating conditions used, spores that were
      naturally sensitive to lysozyme and spores that required EDTA treatment were
      equally heat resistant.

PMID- 4363560
TI  - Developmental changes in vascular reactivity in neonatal skeletal muscle.

PMID- 4363561
TI  - Aggression, schizophrenic reactions and epilepsy: some transcultural
      correlations.

PMID- 4363562
TI  - Chronic venous insufficiency. Discussion and case report of statis ulcer
      treatment.

PMID- 4363564
TI  - Synaptic interactions of reticulospinal neurons and nerve cells in the spinal
      cord of the sea lamprey.

PMID- 4363563
TI  - Synaptic interactions of identified nerve cells in the spinal cord of the sea
      lamprey.

PMID- 4363566
TI  - A light and electron microscopic study of an atypical calcifying odontogenic
      tumor containing "amyloid".

PMID- 4363565
TI  - The effect of collagenase-inhibitor complexes on collagenolytic activity of
      normal and inflamed gingival tissue.

PMID- 4363567
TI  - Electron microscopic studies of organ cultures of tooth germs infected with
      polyoma virus.

PMID- 4363568
TI  - A serological survey for selected viral infections of Rocky Mountain bighorn
      sheep.

PMID- 4363569
TI  - Bluetongue virus and white-tailed deer in an enzootic area of Texas.

PMID- 4363571
TI  - Editorial: Myelography.

PMID- 4363572
TI  - Differentiation of blood islands in chick blastoderms in association with Morris
      hepatoma grafts and its relationship to specific chromosomal changes in the
      hepatomas.

PMID- 4363573
TI  - [Hyperlipoproteinemia and its role in the pathogenesis of arteriosclerosis].

PMID- 4363574
TI  - [Comparative evaluation of the effect of antihypoxic preparations in acute
      hemorrhage and prolonged hypotension].

PMID- 4363575
TI  - [Effect of the sympathetic innervation on the vascular tonus in experimental
      anaerobic intoxication].

PMID- 4363576
TI  - [Prostaglandins and their biological role].

PMID- 4363577
TI  - [Histoenzymological observations on the duodenal Auerbach's plexus in the acute
      phase of experimental Chagas' disease in rats].

PMID- 4363578
TI  - Angiotensin II- and angiotensin 3-induced aldosterone release vivo in the rat.
AB  - The potential role of angiotensin II and its heptapeptide metabolite, des
      aspartyl-angiotensin II, was studied in the conscious unanesthetized rat.
      Aldosterone release was induced by both peptides at physiologic doses (0.72
      nanogram per minute). [I-Sarcosyl-8-alanyl]-angiotensin II (P-113 inhibited
      angiotensin II more effectively than des-aspartyl-angiotensin II (101 percent as
      compared to 82 percent). These results indicate that angiotensin controls
      aldosterone release in the rat and that des-aspartyl-angiotensin II (that is,
      angiotensin III) may be important in this sequence.

PMID- 4363579
TI  - [Principles and the 1973 draft of the "multistep cancer therapy" with optimal
      distance after care. Theoretical viewpoints. 2].

PMID- 4363581
TI  - [Effect of dust containing quartz on the state of the eye].

PMID- 4363580
TI  - [Fluorescent antibody method in the diagnosis and treatment of herpetic
      keratitis].

PMID- 4363582
TI  - Host range studies on xenotropic type C viruses in somatic cell hybrids.

PMID- 4363583
TI  - Characterization of "heavy" and "light" SV40-like particles from a patient with
      PML.

PMID- 4363584
TI  - Poliovirus proteins associated with ribosomal structures in infected cells.

PMID- 4363585
TI  - Integration of SV40 DNA and induction of cellular DNA synthesis after a ts SV40
      infection.

PMID- 4363586
TI  - Fractionation of the double-stranded RNA of maize rough dwarf virus subviral
      particles.

PMID- 4363587
TI  - Adsorption chromatography of polioviruses on porous glass.

PMID- 4363588
TI  - Dependence of interferon induction on cell membrane integrity.

PMID- 4363589
TI  - [The intracellular and resorptive toxic action of viruses].

PMID- 4363590
TI  - [The effect of nucleases on the reproduction of RNA- and DNA-containing viruses].

PMID- 4363591
TI  - [Creatine kinase activity in cells infected by Rous virus].

PMID- 4363592
TI  - [Use of the throbocyte aggregation test for diagnosis of human cytomegalovirus
      infection].

PMID- 4363594
TI  - [Cultivation of several viruses in organ cultures developing on chick embryo
      chorioallantoic membranes].

PMID- 4363593
TI  - [Humoral virus neutralizing antibodies and the sensitivity of 4 species of
      monkeys to disease induced green monkey cytomegalovirus].

PMID- 4363595
TI  - [Formation of oncornavirus type A in the mitochondria of a hamster cell culture
      from a tumor induced by Rous sarcoma virus].

PMID- 4363596
TI  - [Use of a bentonite layer for enterovirus titration by the plaque method].

PMID- 4363597
TI  - [Extraction of specific complement binding antibodies from the sera of pigeons
      with tumors induced by the Schmidt-Ruppin strain of Rous sarcoma virus].

PMID- 4363598
TI  - [Concentration and purification of poliomyelitis and Coxsackie A7 viruses].

PMID- 4363599
TI  - Skeletal maturation of the hand and wrist, a longitudinal study covering two
      years among children of Finnish Lapps.

PMID- 4363600
TI  - A comparison between histochemical and biochemical data on the optic lobe of the
      chicken embryo after unilateral removal of the eye.

PMID- 4363602
TI  - Vinblastine-induced aggregates of smooth endoplasmic reticulum in proximal
      tubular cells of rat kidney.

PMID- 4363601
TI  - "Caveolated cells" characterized by deep surface invaginations and abundant
      filaments in mouse gastro-intestinal epithelia.

PMID- 4363603
TI  - An ultrastructural comparison of the uptake and transport of horseradish
      peroxidase by the rat visceral yolk-sac placenta during mid- and late gestation.

PMID- 4363604
TI  - Ultrastructure of the mouse superior cervical ganglion, with particular reference
      to the pre- and postganglionic elements covering the soma of its principal
      neurons.

PMID- 4363605
TI  - Purification and characterization of a cellular fibrinolytic factor associated
      with oncogenic transformation: the plasminogen activator from SV-40-transformed
      hamster cells.

PMID- 4363606
TI  - Effects of glucagon on activities of hepatic enzymes in sheep.

PMID- 4363607
TI  - Pacemaker activity during aggregation in Dictyostelium discoideum.

PMID- 4363608
TI  - Nucleoside triphosphate hydrolase activities of avian vitelline membrane and
      oviductal lumen.

PMID- 4363609
TI  - Nicotinamide adenine dinucleotide levels in cells of developing chick limbs:
      possible control of muscle and cartilage development.

PMID- 4363610
TI  - [Genetic study of hereditary dentinogenesis imperfecta associated or not with
      hereditary odontogenesis imperfecta].

PMID- 4363611
TI  - Red to white fiber ratios as an index of double muscling in beef cattle.

PMID- 4363612
TI  - Simultaneous measurements in awake rats of drug-induced changes in carotid and
      tail-cuff systolic pressures.

PMID- 4363613
TI  - [Action of purified collagenase on the organic stroma of carious human dentin].

PMID- 4363614
TI  - Glioblastoma multiforme with remote extracranial metastases.

PMID- 4363615
TI  - In vitro degradation and stabilization of the glucocorticoid binding component
      from mouse fibroblasts.

PMID- 4363616
TI  - Steroid-receptor in Pseudomonas testosteroni released by osmotic shock.

PMID- 4363617
TI  - Induction of steroid-binding activity in Pseudomonas testosteroni.

PMID- 4363619
TI  - [Pulmonary sclerosing hemangioma].

PMID- 4363618
TI  - The influence of synthetic anti-estrogens on the binding of tritiated estradiol
      17beta by cytosols of human uterus and human breast carcinoma.

PMID- 4363620
TI  - [The importance of alpha1-fetoprotein in infancy (author's transl)].

PMID- 4363621
TI  - [Chemical synthesis and properties of peptidic hormone analogues (author's
      transl)].

PMID- 4363622
TI  - [Changes in cell surface after viral transformation (author's transl)].

PMID- 4363623
TI  - Clinical neurology.

PMID- 4363625
TI  - Neuroophthalmology.

PMID- 4363624
TI  - Otoneurology.

PMID- 4363627
TI  - Neuroendocrine relationships.

PMID- 4363626
TI  - Genral neurophysiology (biochemical aspects).

PMID- 4363628
TI  - Peripheral nerve surgery.

PMID- 4363629
TI  - Neuropathology.

PMID- 4363631
TI  - [Exploration of hypoglycemia].

PMID- 4363630
TI  - [Thin layer chromatography of various organophosphate and nitrogenated
      insecticides].

PMID- 4363633
TI  - [A case of cytomegalic inclusion disease].

PMID- 4363635
TI  - [Histological classification of breast cancer].

PMID- 4363634
TI  - [Familial hyperlipoproteinemia type IV].

PMID- 4363632
TI  - [Secondary hemorrhages of the brain stem].

PMID- 4363636
TI  - Neutrophil leukocyte collagenase, elastase and serum protease inhibitors in human
      gingival crevicles.

PMID- 4363637
TI  - Two-dimensional polyacrylamide gel electrophoresis separation of low molecular
      weight nuclear RNA.

PMID- 4363639
TI  - Inhibition of deoxyribonuclease in an extract of rat liver nuclei by poly(ADP
      ribose).

PMID- 4363640
TI  - Competitive inhibition of the transport of nucleosides, hypoxanthine, choline and
      deoxyglucose by theophylline, papaverine and prostaglandins.

PMID- 4363638
TI  - Inhibition of adenosine 3',5'-monophosphate accumulation in anterior pituitary
      gland in vitro by growth hormone-release inhibiting hormone.

PMID- 4363642
TI  - Corticosterone suppression of ACTH secretion: actinomycin D sensitive and
      insensitive components of the response.

PMID- 4363641
TI  - "In vitro" binding of cellular, alpha-amanitin sensitive, RNA polymerase to
      infectious, mengovirus-induced double-stranded RNA.

PMID- 4363643
TI  - Evidence from the control of pyrimidine biosynthesis in tissue minces by purines.

PMID- 4363645
TI  - Interactions of parathyroid hormone and plasma membranes from rat kidney.

PMID- 4363644
TI  - Studies of vanadium toxicity in the rat. Lack of correlation with molybdenum
      utilization.

PMID- 4363646
TI  - Lymphocyte and polymorphonuclear enzymes in stress. V. Changes associated with a
      viral infection: Herpes simplex.

PMID- 4363647
TI  - Elevation of hepatic phenylalanine: pyruvate aminotransferase by dibutyryl cyclic
      AMP in rats.

PMID- 4363649
TI  - Combination therapy: some concepts and results.

PMID- 4363650
TI  - Rationale of combined modality therapy for cancer.

PMID- 4363648
TI  - A brief review of pulmonary clearance of bacterial aerosols emphasizing aspects
      of particular relevance to veterinary medicine.

PMID- 4363651
TI  - In vitro-in vivo studies on the susceptibility of the solid Yoshida sarcoma to
      drugs and hyperthermia (42 degrees).

PMID- 4363652
TI  - 5'-Nucleotide phosphodiesterase activity in rat hepatoma.

PMID- 4363654
TI  - Virus oncogenesis and tumor immunogenicity in the mouse mammary tumor system.

PMID- 4363653
TI  - Alpha-(N)-heterocyclic carboxaldehyde thiosemicarbazone inhibitors of
      ribonucleoside diphosphate reductase.

PMID- 4363655
TI  - In vitro determination of thymidine-3H labeling index in human solid tumors.

PMID- 4363656
TI  - Beta-aminoisobutyric acid, a new probe for the metabolism of DNA and RNA in
      normal and tumorous tissue.

PMID- 4363657
TI  - Concanavalin A-induced agglutination and tumorigenicity in virally and
      spontaneously transformed cells derived from BALB-c mice.

PMID- 4363658
TI  - Relationship of rat alpha 1-fetoprotein to growth rate and chromosome composition
      of Morris hepatomas.

PMID- 4363661
TI  - Isozymes of pyruvate kinase in liver and hepatomas of the rat.

PMID- 4363659
TI  - Effects of carcinogens and other agents on histone methylation by a histone
      arginine methyltransferase purified from rat liver cytoplasm.

PMID- 4363660
TI  - Effects of carcinogens and other agents on histone methylation in rat liver
      nuclei by endogenous histone lysine methyltransferase.

PMID- 4363662
TI  - Isolation of a transplantable cell line induced by the MC29 avian leukosis virus.

PMID- 4363663
TI  - Metabolic regulation and adenyl cyclase activity of adrenocortical carcinoma
      cultured cells.

PMID- 4363664
TI  - Separation and characterization of the soluble and insoluble components of
      insoluble laminaran.

PMID- 4363665
TI  - Chemical analysis of exocellular, acid polysaccharides from seven Rhizobium
      strains.

PMID- 4363666
TI  - [Separation of the sulfate and glucuronate fractions of urinary steriods: a new
      analytical method (author's transl)].

PMID- 4363667
TI  - Quantitative immunoelectrophoresis of plasma proteins in acute viral hepatitis,
      extrahepatic biliary obstruction, primary biliary cirrhosis and idiopathic
      haemochromatosis.

PMID- 4363668
TI  - Improved lipid extraction of erythrocytes.

PMID- 4363669
TI  - Control of mitogen--induced lymphocyte activation.  I. The effect of cyclic AMP
      on DNA and RNA synthesis in PHA--stimulated cells.

PMID- 4363670
TI  - Meeting report Twelfth Midwinter Conference of Immunologists. January 6-9, 1973.

PMID- 4363671
TI  - Pyrophosphate stimulation of calcium uptake into cultured embryonic bones. Fine
      structure of matrix vesicles and their role in calcification.

PMID- 4363673
TI  - 5Alpha-dihydrotestosterone "receptor" in the rat hypophysis.

PMID- 4363672
TI  - Further studies on the localization of peroxidase in pig thyroid cells.

PMID- 4363674
TI  - Action of angiotensin on uptake, release and metabolism of 14C-noradrenaline by
      isolated rabbit hearts.

PMID- 4363676
TI  - Training mental health workers to better meet patient needs.

PMID- 4363675
TI  - [Biosynthesis of steroids by human adrenal cancer tissue--effects of ACTH and
      cyclic AMP].

PMID- 4363677
TI  - Using college students as paraprofessionals.

PMID- 4363678
TI  - Influence of catalase and superoxide dismutase on side oxidations involving
      singlet oxygen.

PMID- 4363680
TI  - Changes in adenosine 3',5'-monophosphate level and protein kinase activity by
      glucagon in rat liver nuclei.

PMID- 4363679
TI  - Mechanism of adrenaline-induced lipolysis in adipose tissue.

PMID- 4363681
TI  - Further investigations on the chemical structure of Forssman globoside obtained
      from caprine erythrocyte stroma.

PMID- 4363682
TI  - Membrane-associated adenosine 3',5'-monophosphate-dependent protein kinase and
      its substrates in human erythrocytes.

PMID- 4363683
TI  - A spin-label study on calcium-induced conformational changes of troponin
      components.

PMID- 4363684
TI  - Studies on low temperature spectra of respiratory pigments. II. Spectra of
      cytochromes in respiratory systems between liquid helium and room temperatures.

PMID- 4363685
TI  - The formate hydrogenlyase activity of cytochrome c552-deficient mutants of
      Escherichia coli K12.

PMID- 4363686
TI  - Resistance to skin tumorigenesis by 3-methylcholanthrene in mice susceptible to
      leukemia.

PMID- 4363687
TI  - Feline malignant mammary tumors. II. Immunologic and electron microscopic
      investigations into a possible viral etiology.

PMID- 4363688
TI  - Tumor grading by implantation in embryos. I. Grading of minimum-deviation
      hepatomas.

PMID- 4363689
TI  - Membrane antigen of bovine papilloma virus-induced fibroma cells.

PMID- 4363690
TI  - Restriction of herpes simplex virus type 1 replication in oncornavirus
      transformed cells.

PMID- 4363691
TI  - Type-C RNA virus isolated from SJL-J mice.

PMID- 4363692
TI  - Properties of the common antigen associated with Marek's disease herpesvirus and
      turkey herpesvirus infections.

PMID- 4363693
TI  - Transplacental effects of 1-ethyl-1-nitrosourea in inbred strains of mice. IV.
      Rapid tumor induction in strain crosses.

PMID- 4363694
TI  - Effect of lifetime administration of 2-hydroxyethylhydrazine on tumorigenesis in
      hamsters and mice.

PMID- 4363695
TI  - Transplantation studies on polyoma virus-infected cultures of mouse tooth germs.

PMID- 4363696
TI  - Spontaneous tumors and C-type virus in polyoma-infected aging wild house mice.

PMID- 4363698
TI  - Additional evidence of type-C particles in human placentas.

PMID- 4363697
TI  - An attenuated mouse leukemia virus. I. Origin and immunization.

PMID- 4363699
TI  - Effect of dibutyryl cyclic adenosine 3',5'-monophosphate on in vivo growth of
      Walker 256 carcinoma: isolation of responsive and unresponsive cell populations.

PMID- 4363700
TI  - Antibodies to Epstein-Barr virus-associated antigens in relatives of cancer
      patients.

PMID- 4363701
TI  - B-cell characteristics of human peripheral and cord blood lymphocytes transformed
      by Epstein-Barr virus.

PMID- 4363702
TI  - Mammary tumor virus in strain GR mice in relation to age and tissue type.

PMID- 4363704
TI  - Diversity of envelope antigens on murine type-C RNA viruses.

PMID- 4363703
TI  - Evaluation of an in vitro assay system for carcinogens based on prior infection
      of rodent cells with nontransforming RNA tumor virus.

PMID- 4363706
TI  - C-type virus particles in a reptilian tumor.

PMID- 4363705
TI  - Expression of genes for intracisternal A-particle antigen in somatic cell
      hybrids.

PMID- 4363707
TI  - Differential effect of ionizing radiation on mammary tumor virus activity
      associated with blood cells and mammary tumor cells.

PMID- 4363708
TI  - Hemic cell-associated mammary tumor virus activity in BALB-cfC3H mice.

PMID- 4363710
TI  - Stimulated growth of syngeneic tumors at the site of an ongoing delayed
      hypersensitivity reaction to tuberculin in BALB-c mice.

PMID- 4363709
TI  - Transmission of mammary tumor virus by the GR mouse strain. I. Role of the virus
      in the production of lesions.

PMID- 4363711
TI  - Morphology of a "noninfectious" sarcoma virus.

PMID- 4363712
TI  - Procedure for activating Epstein-Barr virus early antigen in nonproducer cells by
      5-iododeoxyuridine.

PMID- 4363713
TI  - Cellular immunity in mice with simian virus 40-induced mKSA tumors: comparison of
      three assays of tumor immunity.

PMID- 4363714
TI  - Neurotropic effect of 7,12-dimethylbenz(a)anthracene in transplacental
      carcinogenesis.

PMID- 4363716
TI  - Ultrastructural comparison of placental virus with several type-c- oncogenic
      viruses.

PMID- 4363715
TI  - Glandular epithelial cells from mice: a method for selective cultivation.

PMID- 4363718
TI  - [Central pleomorphic adenoma in the mandible: report of a case (author's
      transl)].

PMID- 4363717
TI  - Biogenesis of cocarboxylase in Escherichia coli: regulatory properties of
      thiamine monophosphate kinase.

PMID- 4363719
TI  - Lipids of cultured hepatoma cells. 3. Triglyceride and phosphoglyceride
      biosynthesis in minimal deviation hepatoma 7288C.

PMID- 4363720
TI  - On the levels of alkyl and alk-1-enyl glycerolipids in normal and neoplastic
      tissues: a method of quantification.

PMID- 4363721
TI  - Diseases in feeder calves.

PMID- 4363724
TI  - The tegument of Schistosoma mansoni: observations on the formation, structure and
      composition of cytoplasmic inclusions in relation to tegument function.

PMID- 4363723
TI  - The functional significance of scolex retraction and subsequent cyst formation in
      the cysticercoid larva of Hymenolepis microstoma.

PMID- 4363725
TI  - An in vitro investigation of dynamic processes occurring in the schistosome
      tegument, using compounds known to disrupt secretory processes.

PMID- 4363722
TI  - Oxaloacetate metabolic crossroads in liver. Enzyme compartmentation and
      regulation of gluconeogenesis.

PMID- 4363726
TI  - [Glycolysis and the activity of certain enzymes in the tissues of rats sensitized
      to a carcinogen].

PMID- 4363727
TI  - Liver-spleen scanning in pediatrics.

PMID- 4363728
TI  - Neonatal islet cell adenoma: case report and literature review.

PMID- 4363729
TI  - Studies on hypoglycaemia in primary carcinoma of the liver. A case report and
      review of pathogenetic mechanisms.

PMID- 4363730
TI  - [Non-carcinomatous gastric tumors. Apropos of 35 cases].

PMID- 4363731
TI  - [Iatrogenic gastroduodenal ulcerations. Corticosteroids excluded].

PMID- 4363732
TI  - [Encapsulating peritonitis: diagnostic and etiologic problems].

PMID- 4363733
TI  - [Mesenchymoma-type retroperitoneal tumors. Apropos of 10 cases, including one
      presenting as an unusual invasive fibroma].

PMID- 4363734
TI  - [2 rare and severe complications of hemorrhagic rectocolitis: cancer and
      amyloidosis].

PMID- 4363735
TI  - [2 RARE AND SEVERE COMPLICATIONS OF HEMORRHAGIC RECTOCOLITIS: CANCER AND
      AMYLOIDOSIS].

PMID- 4363737
TI  - Differentiation of water-conducting elements in plants.

PMID- 4363736
TI  - Formation of receptors of glucocorticoid hormones in rat liver chromatin and
      cytoplasm in ontogenesis.

PMID- 4363738
TI  - Action of corticosteroids and ACTH on the chromaffin cells of chick embryo's
      adrenal glands in organ culture.

PMID- 4363739
TI  - [Imipramine-desipramine association in depressive syndromes: EEG study during
      spontaneous sleep].

PMID- 4363740
TI  - The morphology of experimental tumours of the nervous system. II. Intracerebral
      tumours in the rat.

PMID- 4363741
TI  - Oncocytes in the anterior lobe of the human pituitary gland. A light and electron
      microscopic study.

PMID- 4363743
TI  - Heterogeneity and biochemical findings in manic-melancholic disorders.

PMID- 4363742
TI  - [A rare atypical muscular inclusion: "fingerprint bodies" (author's transl)].

PMID- 4363744
TI  - Cyclic 3',5'-adenosine monophosphate stimulates trehalose degradation in baker's
      yeast.

PMID- 4363745
TI  - Respiratory control in cytochrome oxidase.

PMID- 4363747
TI  - Demethylamination of N6-methyldeoxyadenosine by commercial spleen
      phosphodiesterase preparations.

PMID- 4363746
TI  - A novel property of mitochondrial oxidative phosphorylation.

PMID- 4363748
TI  - Kinetics of reactions involving C-550 and cytochrome b559 in chloroplasts at low
      temperature. Evidence for two photoreactions.

PMID- 4363749
TI  - A possible termination factor for transcription in Escherichia coli.

PMID- 4363750
TI  - The reaction of the superoxide ion with iron (3) protoporphyrin IX dimethyl ester
      perchlorate: evidence for a stable dioxygen complex.

PMID- 4363751
TI  - The effect of cyclic AMP and related compounds on the control of protein
      synthesis in reticulocyte lysates.

PMID- 4363752
TI  - Cyclic adenosine 3':5'-monophosphate levels in normal and transformed cells of
      higher plants.

PMID- 4363753
TI  - Deuterium and carbon-13 tracer studies of ethanol metabolism in the rat by 2H, 1H
      decoupled 13C nuclear magnetic resonance.

PMID- 4363754
TI  - On the specificity and pH dependence of ficin-catalyzed hydrolyses. Some
      comparisons with bromelain specificity.

PMID- 4363755
TI  - The heme environment in ferric and ferrous cytochrome c oxidase.

PMID- 4363756
TI  - Influence of globin structure on the state of the heme. 3. Changes in heme
      spectra accompanying allosteric transitions in methemoglobin and their
      implications for heme-heme interaction.

PMID- 4363757
TI  - Prefrontal unit activity during delayed alternation in the monkey. I. Relation to
      direction of response.

PMID- 4363758
TI  - Prefrontal unit activity during delayed alternation in the monkey. II. Relation
      to absolute versus relative direction of response.

PMID- 4363759
TI  - Correlation between brain adenyl cyclase activity and spontaneous motor activity
      in rats after chronic reserpine treatment.

PMID- 4363760
TI  - Early onset in inhibitory functions during synaptogenesis in fetal mouse brain
      cultures.

PMID- 4363761
TI  - Molecular species and membrane forming properties of lecithins in normal liver
      and hepatoma.

PMID- 4363762
TI  - Upper limit of autoregulation of cerebral blood flow in the baboon.

PMID- 4363763
TI  - Stimulation of prostaglandin biosynthesis by adenine nucleotides. Profile of
      prostaglandin release by perfused organs.

PMID- 4363764
TI  - Depressed fatty acid and acetate oxidation and other metabolic defects in
      homogenates from hearts of hamsters with hereditary cardiomyopathy.

PMID- 4363765
TI  - Ontogenesis of the renin-angiotensin system in spontaneously hypertensive and
      normal Wistar rats.

PMID- 4363766
TI  - Evaluation of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides in
      the hexokinase method for determining glucose in serum.

PMID- 4363767
TI  - Radioimmunoassay of angiotensin I, for estimation of plasma renin activity.

PMID- 4363768
TI  - Optic radiation activity during sleep and waking.

PMID- 4363770
TI  - Excitation of cerebral cortical neurons by various polypeptides.

PMID- 4363769
TI  - Binding of D-tubocurarine and alpha-bungarotoxin in normal and denervated mouse
      muscles.

PMID- 4363771
TI  - Electron microscope studies of Fasciola hepatica. XI. Autophagy and parenchymal
      cell function.

PMID- 4363772
TI  - Hormonal responses to intravenous and oral glucose tolerance testing in a patient
      with a gastrinoma and a gastrojejunostomy.

PMID- 4363774
TI  - Saccadic discharges evoked by intracellular stimulation of extraocular
      motoneurons.

PMID- 4363773
TI  - Route of protein loss during a model protein-losing gastropathy in dogs.

PMID- 4363775
TI  - Primary afferent hyperpolarization and presynaptic facilitation of Ia afferent
      terminals induced by large cutaneous fibers.

PMID- 4363776
TI  - Contribution of nonspecific thalamus to sensory evoked activity in cat
      postcruciate cortex.

PMID- 4363777
TI  - Neural control of circulation in Aplysia. I. Motoneurons.

PMID- 4363778
TI  - Neural control of circulation in Aplysia. II. Interneurons.

PMID- 4363779
TI  - Furosemide--pharmacology and cellular mode of action.

PMID- 4363780
TI  - The use of multiple systemic antibiotics in the treatment of patients with burns.

PMID- 4363781
TI  - Experience with infusion and resection in cancer of the liver.

PMID- 4363782
TI  - The carcinogenic effect of 2-oxo-propyl-propylnitrosamine in Sprague-Dawley rats.

PMID- 4363784
TI  - Action of ascorbic--iron combination on the synthesis of blood cells and on the
      activity of phosphatase enzymes.

PMID- 4363783
TI  - Energy coupling and extramitochondrial electron transport in slices of Morris
      hepatoma 3924 A.

PMID- 4363785
TI  - Megakaryocyte abnormalities in thrombotic thrombocytopenic purpura.

PMID- 4363786
TI  - Effect of polymyxin B on antibiotic-resistant Proteus mirabilis.
AB  - The surface properties of polymyxin B-resistant Proteus mirabilis are markedly
      altered by the antibiotic. The effects include the development of susceptibility
      to surface-active agents such as deoxycholate or tris(hydroxymethyl)aminomethane
      and a marked increased osmotic fragility. However, cell wall impermeability to
      various agents such as erythromycin, actinomycin D, bacitracin, lysozyme, and
      triphenyltetrazolium chloride apparently remains intact. These results support
      the concept that the actions of the polymyxins on gram-negative bacteria are
      multiple; the action(s) of the antibiotic responsible for lethality in vitro,
      presumably at the level of the cytoplasmic membrane, may represent only a portion
      of the potential therapeutic effects of the antibiotic in vivo.

PMID- 4363787
TI  - Standardized antimicrobial disc susceptibility testing of anaerobic bacteria: in
      vitro susceptibility of Clostridium perfringens to nine antibiotics.
AB  - The in vitro susceptibility of 43 strains of Clostridium perfringens to nine
      antibiotics was determined by a standardized test for rapid-growing anaerobes.
      Good correlation was established between the agar dilution susceptibility and the
      disc diffusion susceptibility results. The inhibition zone diameters around the
      antibiotic discs, however, were generally much smaller than those of gram
      negative anaerobes previously studied. All of the strains tested were susceptible
      in vitro to chloramphenicol, clindamycin, doxycycline, minocycline, penicillin,
      and vancomycin. Erythromycin showed poor in vitro activity against this organism,
      with only 7% of the strains susceptible, 72% intermediate in susceptibility, and
      21% resistant. In tests of the 43 strains against lincomycin, 58% were
      susceptible, 32.5% were intermediate in susceptibility, and 9.5% were resistant.
      Against tetracycline, 37% of the strains were intermediate in susceptibility and
      the rest were susceptible.

PMID- 4363788
TI  - Locus of divalent cation inhibition of the bactericidal action of polymyxin B.
AB  - The bactericidal effect of polymyxin B upon two Pseudomonas aeruginosa strains
      and two Escherichia coli strains was studied as a function of the concentration
      of the divalent cations Ca(2+) and Mg(2+). Lipid spherules in aqueous suspension
      (liposomes) were prepared from the bacterial phospholipids and were examined for
      the release of trapped glucose induced by polymyxin B under similar conditions of
      divalent cation concentration. In contrast to the bacteria, which were protected
      markedly from the bactericidal action of polymyxin B by Ca(2+) or Mg(2+) at
      concentrations of 2 x 10(-3)m or less, neither cation had any protective effect
      on bacterial liposomes at concentrations up to 2 x 10(-2)m. These observations
      suggest that divalent cations antagonize the bactericidal effect of polymyxin B
      indirectly through interaction with the cell wall rather than at the primary
      membrane locus of action. The interaction of the divalent cations with the cell
      wall prevents access of the antibiotic to the cytoplasmic membrane by mechanisms
      that remain unclear.

PMID- 4363789
TI  - Antiviral action of camptothecin.
AB  - At a concentration of 10 mum, camptothecin inhibited vaccinia deoxyribonucleic
      acid (DNA) synthesis in HeLa cells. Inhibition of viral DNA synthesis was
      observed when the drug was added before infection or at 1 or 2 hr after
      infection. Inhibitory effects of camptothecin on vaccinia DNA synthesis could be
      reversed, even after exposure to the alkaloid for 2 hr. Viral DNA, isolated from
      vaccinia-infected, camptothecin-treated cells, displayed an altered sedimentation
      constant after alkaline sucrose density gradient centrifugation. Incorporation of
      uridine into vaccinia messenger ribonucleic acid was inhibited by camptothecin,
      but the activity of ribonucleic acid polymerase, as tested in isolated vaccinia
      cores, was not affected by the drug. Camptothecin had essentially no effect on
      replication of poliovirus in HeLa cells.

PMID- 4363791
TI  - Autonomous breathing. Report of a case.

PMID- 4363792
TI  - [The determination of organic sulfides (author's transl)].

PMID- 4363790
TI  - The Guillain-Barre syndrome. A clinical and electrodiagnostic study of 25 cases.

PMID- 4363793
TI  - Pituitary tumours.

PMID- 4363794
TI  - Effect of "medical" and surgical adrenalectomy on the ventral prostate and other
      accessory sex glands of the male rat.

PMID- 4363795
TI  - Intermediary mechanisms in asthma. Some informal comments on the pathogenesis of
      the breathing disturbances.

PMID- 4363796
TI  - A cytological and genetic study of oogenesis in Drosophila melanogaster.

PMID- 4363797
TI  - Protein synthesis and secretion in a myogenic cell line.

PMID- 4363798
TI  - Microtubules in the cortical region of the egg of Lymnaea during cortical
      segregation.

PMID- 4363800
TI  - Ultrastructural studies of lizard (Anolis carolinensis) myogenesis in vitro.

PMID- 4363799
TI  - Changes in adenosine 3',5'-monophosphate induced by parathyroid hormone and
      theophylline in the developing rat renal cortex.

PMID- 4363801
TI  - Inhibition of ribosomal RNA synthesis in neurula cells by extracts from blastulae
      of Xenopus laevis.

PMID- 4363802
TI  - Adhesive specificity in normal and transformed mouse fibroblasts.

PMID- 4363804
TI  - Preparation and characterization of chick erythrocyte nuclei from heterokaryons.

PMID- 4363803
TI  - Stimulation of ciliary activity by low levels of extracellular adenine
      nucleotides in the amphibian oviduct.

PMID- 4363805
TI  - N6-substituted adenines induce cell elongation irrespective of the intracellular
      cyclic AMP levels.

PMID- 4363806
TI  - The influence of serum proteins and pH on the effective amino acid concentration
      in tissue culture medium.

PMID- 4363807
TI  - Suitability of silica sol gradients for purification of cell organelles.

PMID- 4363808
TI  - Different cyclic changes in the surface membrane of normal and malignant
      transformed cells.

PMID- 4363809
TI  - Electron microscope observations on the cell walls of some gram-positive
      bacteria.

PMID- 4363810
TI  - Phagocytic activity in the retinal pigment epithelium of the frog Rana pipiens.
      II. Exclusion of Sarcina subflava.

PMID- 4363811
TI  - Observations on the fine structure and peroxidase cytochemistry of normal rat
      liver Kupffer cells.

PMID- 4363813
TI  - [Measurement of plasma renin activity by angiotension I radioimmunoassay].

PMID- 4363812
TI  - Kupffer cell reactions in rat liver under various conditions as observed in the
      electron microscope.

PMID- 4363814
TI  - [Comparative data on the distribution of enteroviruses and bacteriophages in the
      environment].

PMID- 4363815
TI  - Peripheral nerve function in long-term therapy with diphenylhydantoin. A clinical
      and electrophysiologic correlation.

PMID- 4363816
TI  - Adverse interaction between steroid hormones and anticholinesterase drugs.

PMID- 4363817
TI  - Paroxysmal signs and symptoms in multiple sclerosis.

PMID- 4363818
TI  - Morphologic changes associated with combined BCNU and radiation therapy in
      glioblastoma multiforme.

PMID- 4363819
TI  - Effect of pentoxifylline on cerebral edema in cats.

PMID- 4363821
TI  - [Phenotyping of secondary hyperlipoproteinemia in diabetics].

PMID- 4363820
TI  - [Epidemiologic study of cytomegalovirus infections. II. Studies on the mode of
      transmission of the virus].

PMID- 4363822
TI  - Endogenously blocked high affinity estradiol receptors in the immature and mature
      rat uterus.

PMID- 4363823
TI  - Effect of intravenous infusion of isethionate on rats.

PMID- 4363824
TI  - Effects of glucagon and dibutyryl cyclic AMP on the phosphorylase activity and
      gluconeogenesis in rat liver slices.

PMID- 4363825
TI  - Comparative studies of the viruses rescued from polyoma tumor cell line.

PMID- 4363826
TI  - Estrogen receptors in bone. An evaluation of the uptake of estrogen into bone
      cells.

PMID- 4363828
TI  - Evidence for the involvement of superoxide anion in dopamine-beta-hydroxylase
      system.

PMID- 4363829
TI  - Typing of isolates of herpes simplex-virus by mixed agglutination.

PMID- 4363827
TI  - Induction of tumors of the stomach and esophagus in inbred Chinese hamsters by
      oral diethylnitrosamine.

PMID- 4363830
TI  - Pituitary-adrenal function in adult androgenized female rats.

PMID- 4363831
TI  - [The importance of mammography in early detection of breast cancer (author's
      transl)].

PMID- 4363832
TI  - [The use of electronic data processing in nuclear medicine (author's transl)].

PMID- 4363833
TI  - Specific unresponsiveness to skin allografts in mice. 3. Synergistic effect of
      tissue extracts, Bordetella pertussis, and antilymphocytic serum.

PMID- 4363834
TI  - [Significance of juxtaglomerular apparatus for the function of the nephron].

PMID- 4363835
TI  - [Appearance of abnormal macrophages in the alveoli of the rat following treatment
      with an appetite depressant (chlorphentermine)].

PMID- 4363836
TI  - [Light and electron microscopical studies on localization and differentiation of
      activities of nucleoside phosphatase in the Schweigger-Seidel capillary envelopes
      in the spleen of swine].

PMID- 4363837
TI  - [Recent findings on ultrastructure of amitosis in interrenal cells of Rana
      temporaria L].

PMID- 4363838
TI  - A histochemical study on the interstitial cells of the rat renal medulla.

PMID- 4363839
TI  - Liver biopsy.

PMID- 4363840
TI  - [Effect of the primary distribution of the microbial aerosol in the respiratory
      system on the size of the infecting dose (a review of the literature)].

PMID- 4363841
TI  - Hyperresponsiveness to lysine-vasopressin in Cushing's disease.

PMID- 4363842
TI  - Plasma testosterone in male puberty. I. Physiology of plasma testosterone.

PMID- 4363843
TI  - The uptake and metabolism of (4-14C)testosterone in human breast cancer growth in
      organ culture.

PMID- 4363844
TI  - Biological activity of synthetic human corticotropin with revised amino acid
      sequence.

PMID- 4363845
TI  - Growth retardation in the Lesch-Nyhan syndrome.

PMID- 4363846
TI  - Angiography in gastric tumours.

PMID- 4363848
TI  - Herpesvirus infections in pregnancy: a comparison of neutralizing antibody titers
      in mothers and their infants.

PMID- 4363847
TI  - On the regulation of estrogen production by cortisol and ACTH in human pregnancy
      at term. Memorial Foundation award thesis.

PMID- 4363849
TI  - Sodium dodecylsulfate-dependent anomalies in gel electrophoresis: alterations in
      the banding patterns of foot-and-mouth disease virus polypeptides.

PMID- 4363850
TI  - Activation of DNA primer for DNA polymerase as an ultrasensitive assay for a
      subgroup of enzymes with deoxyribonuclease activity.

PMID- 4363851
TI  - An improved protein binding assay for cyclic AMP.

PMID- 4363852
TI  - A sensitive analytical method for the detection and quantitation of adenosine in
      biological samples.

PMID- 4363853
TI  - A fast and sensitive method for the analysis of modified nucleosides in tRNA.

PMID- 4363855
TI  - The effect of two synthetic ACTH analogues on the metabolism of biogenic amines
      in the rat brain.

PMID- 4363854
TI  - The assay of ATP by the luciferin-luciferase method. Interference by a bacterial
      phosphatase enzyme stable to perchlorate treatment.

PMID- 4363856
TI  - Experimental disciform serous retinal detachment. I. Method of production and
      histology.

PMID- 4363857
TI  - Experimental disciform serous retinal detachment. II. Autoradiography of
      photoreceptor protein metabolism.

PMID- 4363859
TI  - [The effect of molecular oxygen on anaerobic bacteria of the genus Clostridium].

PMID- 4363858
TI  - Pseudomonas blepharoconjunctivitis: a complication of combination chemotherapy.

PMID- 4363860
TI  - [Several properties of pea chloroplast adenylate kinase].

PMID- 4363861
TI  - Studies on the radioiodination of very low density lipoprotein obtained from
      different mammalian species.

PMID- 4363862
TI  - Long-term storage of erythrocytes for quantitative analyses of lipids.

PMID- 4363863
TI  - A review of methods and metabolic studies associated with the radioiodination of
      lipoproteins.

PMID- 4363864
TI  - Proceedings: A possible gene assignment to chromosome 21.

PMID- 4363865
TI  - Proceedings: The human loci for phosphopyruvate hydratase and guanylate kinase
      are syntenic with the PGD-PGM1 linkage group in man-Chinese hamster somatic cell
      hybrids.

PMID- 4363866
TI  - Proceedings: The genetics of the antiviral state in human cells.

PMID- 4363867
TI  - Proceedings: Assignment of the gene in man for mitochondrial superoxide dismutase
      (indophenol oxidase-B, tetrameric) to chromosome 6.

PMID- 4363868
TI  - Proceedings: Assignment of the second locus of adenylate kinase to chromosome 1p:
      preliminary data.

PMID- 4363869
TI  - Proceedings: Evidence for synteny between the human loci for the HLA
      histocompatibility antigen, phosphoglucomutase3, malic enzyme (cytoplasmic), and
      indophenol oxidase B (tetrameric).

PMID- 4363870
TI  - Proceedings: Regional assignments of seven enzyme loci on chromosme 1 of man.

PMID- 4363871
TI  - Proceedings: The expression of hepatic functions in mouse hepatoma x human
      leukocyte hybrids.

PMID- 4363872
TI  - Temperature-sensitive mutations in Drosophila melanogaster. XI. Male sterile
      mutants of the Y chromosome.

PMID- 4363873
TI  - Studies of oogenesis in Urechis caupo. II. Accumulation during oogenesis of
      carbohydrate, RNA, microtubule protein, and soluble, mitochondrial, and lysosomal
      enzymes.

PMID- 4363874
TI  - Sleep, sleep deprivation, photosensitivity and epilepsy.

PMID- 4363875
TI  - 5-Hydroxyindoleacetic acid and homovanillic acid in cerebrospinal fluid of
      patients with neurological diseases.

PMID- 4363876
TI  - [Effect of a physical load of varying duration on the function of the hypothalamo
      hypophyseo-adrenal system in rats].

PMID- 4363877
TI  - [Participation of the direct spino- and cuneocerebellar tracts in the formation
      of potentials evoked in the cerebellum on stimulation of the nerves].

PMID- 4363878
TI  - Intracellular conversions of deoxyribonucleosides by Novikoff rat hepatoma cells
      and effects of hydroxyurea.

PMID- 4363879
TI  - The deoxyribonucleoside transport systems of cultured Novikoff rat hepatoma
      cells.

PMID- 4363880
TI  - Effect of growth conditions on the activity of ornithine decarboxylase in
      cultured hepatoma cells. I. Effect of amino acid supply.

PMID- 4363881
TI  - The effect of calcium concentration on ACTH stimulation of steroidogenesis in
      mouse adrenal tumor cells.

PMID- 4363882
TI  - Plasma membrane ectoglycosyltransferase activity of L1210 murine leukemic cells.

PMID- 4363883
TI  - The nervous control of autotomy in Carcinus maenas.

PMID- 4363884
TI  - Angiofibroma: a treatment approach.

PMID- 4363885
TI  - The medical and surgical treatment of nasal polyps.

PMID- 4363886
TI  - [Multilocular renal cyst in infancy].

PMID- 4363887
TI  - Role of the spleen in membrane conditioning and hemolysis of spur cells in liver
      disease.

PMID- 4363888
TI  - Treatment of hyperlipidemia.

PMID- 4363889
TI  - Thyroid thermogenesis.

PMID- 4363890
TI  - Letter: Hypertension and hydronephrosis.

PMID- 4363891
TI  - Studies on the neuropharmacology of papaverine. 3. The inhibition of ganglionic
      transmission.

PMID- 4363892
TI  - Comparative study of brain scintiphotography, cerebral angiography and
      pneumencephalography in detection of gliomas.

PMID- 4363893
TI  - The vascular supply of eosinophilic and mixed pituitary adenomas in acromegalic
      patients.

PMID- 4363894
TI  - Aspects of the venous drainage of the pons and the mesencephalon.

PMID- 4363895
TI  - Radioisotope serial brainscanning.

PMID- 4363896
TI  - Type-specific tumor patterns in the cerebral radioangiography (CRAG): results in
      195 patients.

PMID- 4363897
TI  - Functional radioangiographic studies of cerebral vascular haemodynamics
      (preliminary report).

PMID- 4363898
TI  - A case of chronic adhesive arachnoiditis after lumbar myelography with methiodal
      sodium.

PMID- 4363899
TI  - Cytomegalic inclusion diseases; a clinico-pathological correlation.

PMID- 4363900
TI  - Diagnostic problems of cerebral metastases.

PMID- 4363901
TI  - [A case of "granulosa cell tumor" of the breast].

PMID- 4363902
TI  - [Metabolism and mechanism of vitamin D].

PMID- 4363903
TI  - [Contrast medium studies of the internal acoustic meatus (cisternomeatography)--a
      system for early diagnosis of acoustic nerve tumors].

PMID- 4363904
TI  - Renin-angiotensin activation in hyperacute renal xenograft rejection.

PMID- 4363905
TI  - Activation of the renal erythropoietic factor by a cyclic AMP-dependent protein
      kinase.

PMID- 4363906
TI  - Erythrocyte association and interferon production by minute virus of mice.

PMID- 4363907
TI  - Inhibitory effect of sodium cyclamate and sodium saccharin on tumor induction by
      2-acetylaminofluorene in rats.

PMID- 4363908
TI  - Inhibition at the T-cells of the spinothalamic tract: a neurophysiological basis
      for electrically induced analgesia.

PMID- 4363909
TI  - Histochemical enzyme changes in epidermis of manganese-deficient fetal mice.

PMID- 4363910
TI  - Effects of adrenal steroids on brain function and behavior.

PMID- 4363911
TI  - How do neurones secrete peptides? Exocytosis and its consequences, including
      "synaptic vesicle" formation, in the hypothalamo-neurohypophyseal system.

PMID- 4363912
TI  - Effects of acute and chronic adminstration of narcotic analgesics on growth
      hormone and corticotrophin (ACTH) secretion in rats.

PMID- 4363913
TI  - Effects of morphine and related drugs on the corticotrophin (ACTH)-stress
      reaction.

PMID- 4363914
TI  - Antagonism between morphine and the polypeptides ACTH, ACTH1-24 and beta-MSH in
      the nervous system.

PMID- 4363915
TI  - The influence of peptides derived from corticotrophin (ACTH) on performance.
      Structure activity studies.

PMID- 4363916
TI  - Behavioral aspects of melanocyte-stimulating hormone (MSH).

PMID- 4363917
TI  - Glucocorticoid binding sites in rat brain: subcellular and anatomical
      localizations.

PMID- 4363918
TI  - Steroid feedback mechanisms in pituitary-adrenal function.

PMID- 4363919
TI  - Effect of short-term upright posture on plasma angiotensin II in man.

PMID- 4363920
TI  - [Effect of clonazepam in the long-term oral treatment of severe epilepsy in
      children].

PMID- 4363921
TI  - Altered action of parathyroid hormone by chlorpropamide.

PMID- 4363922
TI  - Charge to the community: some early effects of a state hospital system's change
      of policy.

PMID- 4363923
TI  - The principle of energy transduction in the cytochrome c oxidase region of the
      respiratory chain.

PMID- 4363924
TI  - Energy coupling in cytochrome oxidase.

PMID- 4363925
TI  - Enzymic generators of membrane potential in mitochondria.

PMID- 4363926
TI  - Evaluation of the chemiosmotic interpretation of active transport in bacterial
      membrane vesicles.

PMID- 4363927
TI  - The function of cytochrome c.

PMID- 4363928
TI  - Conduction within the cytochrome c molecule.

PMID- 4363929
TI  - Heme-heme interaction between the cytochromes of the mitochondrial respiratory
      chain.

PMID- 4363930
TI  - Solid state physical mechanisms of biological energy transduction.

PMID- 4363931
TI  - The separation of electrons and protons during electron transfer: the distinction
      between membrane potentials and transmembrane gradients.

PMID- 4363932
TI  - [Determination of the serotypes of strains of Bordetella pertussis isolated
      between 1952 and 1971 in Rumania].

PMID- 4363933
TI  - [Electronoptic diagnosis of paravaccinal virus infections].

PMID- 4363934
TI  - [Laboratory diagnosis of paravaccinia].

PMID- 4363935
TI  - Irreversibility of the alteration in RNA transport induced by an azo-dye
      carcinogen in the rat liver.

PMID- 4363936
TI  - Studies on a possible phosphoryl-enzyme intermediate in the catalytic reaction of
      yeast phosphoglycerate kinase.

PMID- 4363937
TI  - The incorporation of glycerol into mitochondrial lipids during neonatal renal
      compensatory growth.

PMID- 4363938
TI  - Choline kinase and choline phosphotransferase in developing fetal rat lung.

PMID- 4363939
TI  - A functional acetylcholine receptor in the human erythrocyte.

PMID- 4363940
TI  - Formation of mengovirus-like particles in cell-free extracts from virus-infected
      cells.

PMID- 4363941
TI  - In vivo covalent binding of 14CCl4 metabolites in liver microsomal lipids.

PMID- 4363942
TI  - Release of the inhibition of messenger RNA translation in extracts of interferon
      treated Ehrlich ascites tumor cells by added transfer RNA.

PMID- 4363943
TI  - Use of a concanavalin A polymer to isolate right side-out vesicles of purified
      plasma membranes from eukariotic cells.

PMID- 4363944
TI  - The metabolism of very low density lipoprotein and chylomicrons by purified
      lipoprotein lipase from rat heart and adipose tissue.

PMID- 4363946
TI  - Isolation of the plasma membrane of a trypanosomatid flagellate: general
      characterisation and lipid composition.

PMID- 4363947
TI  - Effect of ATP on the intermediary steps of the reaction of the (Na+ plus K+)
      dependent enzyme system. 3. Effect on the p-nitrophenylphosphatase activity of
      the system.

PMID- 4363948
TI  - A sensitive method for the bioassay of acetylcholine.

PMID- 4363949
TI  - Mechanism of the inhibitory actions of some spasmogens on the bradykinin
      relaxation of the guinea-pig ileum.

PMID- 4363950
TI  - Effects of cell adhesion of the substratum on the growth of chick embryo
      fibroblasts.

PMID- 4363951
TI  - A comparison of the utilization of thymine and thymidine for the synthesis of DNA
      thymine in Novikoff hepatoma cells.

PMID- 4363952
TI  - [Study of the pituitary corticotropin reserve with metyrapone in subjects treated
      with a steroid association and with the single components].

PMID- 4363953
TI  - GH and ACTH secretion in insulin-induced hypoglycemia in normal children.

PMID- 4363954
TI  - [Changes in the gas-chromatographic pattern of urinary steroids induced with
      prolonged corticotropin stimulation].

PMID- 4363955
TI  - Stereological analysis of the guinea pig pancreas. I. Analytical model and
      quantitative description of nonstimulated pancreatic exocrine cells.
AB  - A stereological model which provides detailed quantitative information on the
      structure of the fasted, nonstimulated gland has been developed for the guinea
      pig pancreas. The model consists of morphologically defined space and membrane
      compartments which were used to describe the general composition of the tissue
      and the specific components of exocrine cells. The results are presented, where
      appropriate, relative to a cubic centimeter of pancreas, a cubic centimeter of
      exocrine cell cytoplasm, and to the volume of an average exocrine cell. The
      exocrine cells, accounting for 82% of the pancreas volume, consisted of 54%
      cytoplasmic matrix, 22% rough-surfaced endoplasmic reticulum (RER), 8.3% nuclei,
      8.1% mitochondria, 6.4% zymogen granules, and 0.7% condensing vacuoles. Their
      total membrane surface area was distributed as follows: 60% RER, 21%
      mitochondria, 9.9% Golgi apparatus, 4.8% plasma membranes, 2.6% zymogen granules,
      1.8% plasma membrane vesicles, and 0.4% condensing vacuoles. The application of
      this model to the study of membrane movements associated with the secretory
      process is discussed within the framework of an analytical approach.

PMID- 4363956
TI  - Rapid changes in nucleoside transport induced by growth inhibitors. Studies with
      neoplastic mast cells.
AB  - Aqueous extracts of murine embryonic or uterine tissue, or [(6)N]O(2)'-dibutyryl
      3',5'-adenosine monophosphate (dbc-AMP) which were cytostatic for the murine
      mastocytoma P815Y in vitro also induced rapid changes in the incorporation of
      exogenous nucleosides into acid-insoluble material. However, these alterations
      were not a consequence of growth arrest. Different dose-response curves were
      obtained for cytostasis and inhibition of [(3)H]-nucleoside incorporation, and
      changes in [(3)H]thymidine uptake were detected within 15 min of treatment with
      the inhibitors. Also, there were differential effects of each inhibitor on the
      incorporation of (3)H-labeled thymidine, uridine, adenosine, or choline into acid
      insoluble material.

PMID- 4363957
TI  - Effects of cyclic AMP and Sephadex fractions of chick embryo extract on cloned
      retinal pigmented epithelium in tissue culture.
AB  - The effects of dibutyryl cyclic 3',5'-adenosine monophosphate (BcAMP) and
      Sephadex G-25 fractions of chick embryo extract on the growth rate, morphology,
      and pigmentation of normal chick retinal pigmented epithelium (PE) were
      investigated. Seven cloned PE cell lines were each grown in modified Ham's F-12
      medium alone (F-12), or in F-12 supplemented with either high molecular weight
      (H) or low molecular weight (L) fractions of chick embryo extract. Cells grown in
      F-12 alone or in L medium formed compact epithelial sheets, whereas cells grown
      in H had a fibrocytic appearance and formed poorly organized monolayers. In H
      plus BcAMP, cell morphology was more epithelioid than in H alone, and generally
      the monolayers appeared more differentiated. Under each of these three culture
      conditions, 2 x 10(-4) M BCAMP retarded the increase in cell number and decreased
      the final number of cells per culture dish, but had little effect on plating
      efficiency. BcAMP also increased the rate of cell adhesion to a plastic
      substratum. Pigmentation was marked in cultures grown in F-12 or in L alone, but
      the addition of BcAMP dramatically reduced visible pigmentation. This effect was
      reversed when BcAMP was removed from the culture medium. Thus BcAMP modifies cell
      and colonial morphology, rate of cell accumulation, adhesive properties, and
      pigmentation of normal PE cells.

PMID- 4363958
TI  - Characterization of a unique muscle cell line.
AB  - A clonal cell line derived from a mouse neoplasm is described which shares many
      properties with smooth muscle. The cells have electrically excitable membranes
      capable of generating overshooting action potentials, and they contract both
      spontaneously and with electrical stimulation. They respond to the iontophoretic
      application of acetylcholine with a depolarizing response, and to norepinephrine
      with a hyperpolarizing response. Electron microscopy reveals that the cells have
      a morphology similar in many, but not all, respects to that of smooth muscle
      cells in vivo. The cells secrete soluble collagen-like molecules in addition to
      several proteins of undefined function. Finally, there is an increase in the
      specific activities of creatine phosphokinase and myokinase associated with
      increased cell density and the cessation of cell division.

PMID- 4363959
TI  - Resolution of three distinct populations of nerve endings from rat brain
      homogenates by zonal isopycnic centrifugation.
AB  - Conditions have been established for the fractionation of subcellular components
      of rat forebrain homogenates by zonal isopycnic equilibration in continuous
      sucrose density gradients using a B-XIV rotor. The fractions were analyzed
      biochemically and by ultra-structural morphometry. Starting from postnuclear
      supernates of forebrain homogenates, it has been possible to resolve three
      distinct populations of nerve endings from one another, as well as from free
      mitochondria and myelin fragments. The three types of nerve endings differ in
      their apparent specific gravity, their biochemical properties, and their ability
      selectively to accumulate exogenous transmitter substances in vitro. These three
      particle populations are likely to represent, in order of increasing modal
      equilibrium density, (a) cholinergic nerve endings, characterized by their high
      content of acetylcholine, (b) gamma-amino butyric acid (GABA)-containing nerve
      endings with high glutamate decarboxylase activity and the ability to accumulate
      exogenous GABA, (c) adrenergic nerve endings that accumulate exogenous dopamine
      and noradrenaline and exhibit high monoamine oxidase activity.

PMID- 4363960
TI  - Ultrastructural localization of concanavalin A receptors in somatic cell hybrids
      between normal mouse cells and simian virus 40-transformed rat cells.

PMID- 4363961
TI  - Bulk isolation of mouse hepatocyte gap junctions. Characterization of the
      principal protein, connexin.

PMID- 4363962
TI  - A single extraction thin-layer chromatographic method in current use.

PMID- 4363963
TI  - Quantitative spectrodensitometry on morphine and amphetamine on thin layer
      chromatograms.

PMID- 4363965
TI  - Inhibition of free fatty acid mobilization by colchicine.
AB  - Segments of epididymal adipose tissue from normal male rats were incubated with
      micromolar concentrations of colchicine for different periods of time up to 4 hr,
      and the mobilization of free fatty acids (FFA) was measured during a subsequent
      reincubation. Although pretreatment with colchicine did not alter basal
      unstimulated FFA release, mobilization of FFA in the presence of epinephrine or
      theophylline was reduced. However, neither lipolysis, as judged by glycerol
      production, nor cyclic AMP accumulation was impaired under the same conditions.
      To assess the possibility that colchicine might limit production of fatty acids
      by accelerating the entry and metabolism of glucose into adipocytes, the
      metabolism of glucose by adipose tissue was studied. Pretreatment with colchicine
      did not affect uptake of glucose nor its oxidation to CO(2), although colchicine
      treated tissues did have slightly more [(14)C]glucose incorporated into the
      glyceride moiety of triglyceride. When adipose tissues pretreated with colchicine
      were incubated in an albumin-free medium, no reduction in FFA production by
      colchicine was observed. Because no FFA release occurs in albumin-free media,
      this experiment suggests that colchicine-induced inhibition of FFA mobilization
      results from impaired extrusion of FFA from adipose cells.

PMID- 4363964
TI  - Glycosphingolipids from rabbit aorta, plasma, and red blood cells: effects of
      high cholesterol-high fat diets on fatty acid distribution and quantity of
      glycosphingolipids.
AB  - Four glycosphingolipids were isolated from rabbit aorta, plasma, and red blood
      cells. They were identified, by thin-layer chromatography and by quantitative
      analysis of hexose and fatty acid, as cerebroside, diglycosyl ceramide,
      triglycosyl ceramide, and globoside. The rabbits had been maintained on a normal
      diet or on one of three high cholesterol diets for 180 days. The quantities of
      the glycosphingolipids and their fatty acid distributions were determined, and
      comparisons were made between the control and experimental animals. Aorta and
      plasma glycosphingolipids were more affected by the high cholesterol diets than
      were those from red blood cells. The effects on aorta and plasma
      glycosphingolipids were similar. The amount of cerebroside was increased in aorta
      and plasma in all animals in the experimental groups. The amount was also
      increased in red blood cells in rabbits from two of the experimental groups. The
      average fatty acid chain length was greater in the lipids from the experimental
      animals than in those from the control animals for all measured
      glycosphingolipids from aorta. The average chain length was also greater in
      cerebrosides from the experimental animals from all three tissues. Probably the
      most notable differences in the experimental animals were the increased 24:1/24:0
      ratios and the increased concentrations of 24:2. These increases occurred in
      nearly all samples from plasma and aorta, but not in red blood cells. There was
      also an increase of total unsaturated fatty acids in aorta cerebrosides from the
      experimental animals. Except for the increase in 24:2, lard generally caused more
      deviation from normal than did cottonseed oil when the level of cholesterol in
      the diet was 1%.

PMID- 4363966
TI  - 3-Hydroxy-3-methylglutaryl CoA reductase and mevalonate kinase of Neurospora
      crassa.
AB  - Two enzymes of polyisoprenoid synthesis, 3-hydroxy-3-methylglutaryl coenzyme A
      (HMG CoA) reductase (mevalonate:NADP oxidoreductase [acylating CoA], EC 1.1.1.34)
      and mevalonate kinase (ATP:mevalonate 5-phosphotransferase, EC 2.7.1.36), are
      present in the microsomal and soluble fractions of Neurospora crassa,
      respectively. HMG CoA reductase specifically uses NADPH as reductant and has a
      K(m) for dl-HMG CoA of 30 micro M. The activities of HMG CoA reductase and
      mevalonate kinase are low in conidia and increase threefold during the first 12
      hr of stationary growth. Maximum specific activities of both enzymes occur when
      aerial hyphae and conidia first appear (2 days), but total activities peak later
      (3-4 days). Addition to the growth media of ergosterol or beta-carotene, alone or
      in combination, does not affect the specific or total activity of either enzyme.
      The mevalonate kinase of N. crassa, purified 200-fold to a specific activity of 5
      micro moles/min/mg, is free from HMG CoA reductase, phosphomevalonate kinase,
      ATPase, adenylate kinase, and NADH oxidase activities. Mevalonate kinase
      specifically requires ATP as cosubstrate and exhibits a marked preference for
      Mg(2+) over Mn(2+), especially at high ratios of divalent metal ion to ATP.
      Kinase activity is inhibited by p-hydroxymercuribenzoate, and this inhibition is
      partially prevented by mevalonate or MgATP. Optimum activity occurs at pH 8.0-8.5
      and at about 55 degrees C. The Neurospora kinase, like that of hog liver, has a
      sequential mechanism for substrate addition. The Michaelis constants obtained
      were 2.8 mM for dl-mevalonate and 1.8 mM for MgATP(-2). Geranyl pyrophosphate is
      an inhibitor competitive with MgATP (K(i) = 0.11 mM).

PMID- 4363967
TI  - High performance liquid chromatography of ceramides: application to analysis in
      human tissues and demonstration of ceramide excess in Farber's disease.
AB  - Conditions have been determined for the benzoylation of ceramides containing
      nonhydroxy and hydroxy fatty acids, and a high performance liquid chromatography
      system for the separation and measurement of these derivatives has been devised
      that is capable of good resolution and high sensitivity. These methods have been
      used to determine quantitatively the levels of ceramides in human tissues, and in
      serum and urine, and to demonstrate elevated amounts of ceramide in Farber's
      disease urine and tissues.

PMID- 4363968
TI  - Structure and composition of sulfatides isolated from livers of patients with
      metachromatic leukodystrophy: galactosyl sulfatide and lactosyl sulfatide.
AB  - The livers of four patients with metachromatic leukodystrophy contained
      galactosyl sulfatide and lactosyl sulfatide, whereas these substances were
      undetectable in normal human liver. On the basis of methanolysis and
      permethylation studies, both sulfatides were shown to be substituted with sulfate
      at the C-3 position of the galactose moiety. Examination of the fatty acid
      compositions of these sulfatides showed that C(22:0) and higher 2-hydroxy and
      nonhydroxy fatty acids predominated in both. Both sulfatides contained the same
      long-chain bases, predominantly sphingosine, dihydrosphingosine, and
      phytosphingosine. Using as criteria the proportion of lactosyl sulfatide to
      galactosyl sulfatide, and the fatty acid and long-chain base compositions, the
      liver sulfatides from subjects with metachromatic leukodystrophy closely resemble
      those in the kidney and differ from those in brain and peripheral nerve.

PMID- 4363969
TI  - Steryl esters and their relationship to normal and diseased human central nervous
      system.
AB  - The composition and distribution of steryl esters in human diseased or developing
      brain tissue has been studied. The abnormal brain conditions included
      sudanophilic leukodystrophy, multiple sclerosis plaque, subacute sclerosing
      panencephalitis, and an old cerebral infarction and two types of brain-derived
      tumors. In addition to the above abnormal tissue, steryl esters were also
      examined in developing and normal adult human brain. It was found upon
      subcellular fractionation that the steryl ester was localized mainly in the
      soluble nonparticulate material. A cholesteryl ester-rich fraction, floating on
      top of distilled water after centrifugation, was recovered only in the developing
      brain or in instances where there was myelin damage. The sterol portion of the
      steryl ester was largely cholesterol. The fatty acid moiety was mainly composed
      of C(16), C(18), and C(20) fatty acids. The dominant fatty acid was oleic acid,
      and the proportion of this fatty acid increased in demyelination. Although there
      were great differences in the quantities of steryl ester found, the fatty acid
      profiles of normal developing and adult brain were quite similar. As has been
      noted by others, the fatty acid composition of brain steryl esters most closely
      resembles that of brain phosphatidylcholine.

PMID- 4363970
TI  - Permeability changes induced by peroxidation in liposomes prepared from human
      erythrocyte lipids.
AB  - The diffusion of [2-(14)C]glucose out of liposomes prepared from extracted human
      erythrocyte lipids was examined. Increased glucose efflux was observed when the
      lipids were treated with hydrogen peroxide and CuCl(2) before liposome formation,
      and this phenomenon required both peroxide and metal. Peroxidation of these
      lipids also resulted in the destruction of polyunsaturated fatty acids and the
      generation of conjugated dienes, but neither of these processes appeared to be
      the sole cause of increased glucose efflux. Thin-layer chromatography and the
      effects of aqueous washes suggested that surface-active lysophosphatides or other
      lipid degradation products were responsible for the increased permeability of the
      treated liposomes. It is suggested that the behavior of this liposome model
      system may be relevant to the high permeability and fragility of vitamin E
      deficient erythrocytes.

PMID- 4363971
TI  - Quantitative determination of lysolecithin and sphingomyelin in phospholipid
      mixtures by thin-layer chromatography as applied to the thymus of the fmfm mouse.
AB  - Lysolecithin and sphingomyelin may be readily separated from other phospholipids
      on thin-layer plates impregnated with silver nitrate using the solvent system
      chloroform-methanol-concentrated ammonium hydroxide 65:35:8. Quantitation is
      carried out by determining the phosphorus content of the developed bands. The
      minimum amount of phospholipid that can be quantitatively determined is that
      which contains 0.7 micro g of phosphorus. This method has been used for the
      determination of lysolecithin and sphingomyelin in the tissues of mice having
      foam-cell reticulosis.

PMID- 4363972
TI  - Simple assay for monoacylglycerol hydrolase activity of rat adipose tissue.
AB  - A simple, sensitive, and specific assay for monoacylglycerol hydrolase activity
      of rat adipose tissue is described. Monoacyl[(3)H]glycerols with different chain
      lengths (8-18 carbon atoms) and different degrees of unsaturation in mixed
      micellar solution with different detergents can be used as substrates. The
      [(3)H]glycerol that is produced is isolated in a one-step liquid-liquid partition
      procedure. For routine purposes monooleoyl[(3)H]glycerol was found to be the most
      suitable substrate. A simple method for the chemical synthesis and purification
      of this substrate in high yield is given. The assay allows rapid serial sampling
      of enzymatic activity with a high reproducibility.

PMID- 4363973
TI  - Use of stainless steel wire coil prosthesis in treatment of anastomotic
      dehiscence after cervical tracheal resection.

PMID- 4363974
TI  - Arteriographic findings in mediastinal chemodectoma.

PMID- 4363975
TI  - Mucus gland adenoma of the bronchus.

PMID- 4363976
TI  - [Infections of the eye in childhood].

PMID- 4363977
TI  - [Hemorrhagic complications in the nervous system during anticoagulant therapy
      (author's transl)].

PMID- 4363978
TI  - Granular-cell tumor. Review of the literature and report of a case.

PMID- 4363979
TI  - The effect of systemic disorders on the dental pulp in experimental animals.

PMID- 4363980
TI  - [Mixed tumor of the parotid Intraductal gland].

PMID- 4363981
TI  - [Preoperative chemotherapy in Wilm's tumor in children].

PMID- 4363982
TI  - [The mechanism of anaerobic gastrointestinal infection in man].

PMID- 4363983
TI  - Competitive protein-binding assay for corticoids in the peripheral plasma of the
      immature chicken.

PMID- 4363984
TI  - Isolation and purification of turkey heme proteins.

PMID- 4363985
TI  - [Peroneal nerve palsy after trauma of the ankle (author's transl)].

PMID- 4363986
TI  - [Subcutaneous histiocytoma in a boy].

PMID- 4363988
TI  - [Herpes simplex encephalitis. Acute necrotizing encephalitis and benign herpes
      simplex encephalitis].

PMID- 4363987
TI  - Steroid metabolism by human breast and rat mammary carcinomata.

PMID- 4363989
TI  - [Gas gangrene treated with hyperbaric oxygen].

PMID- 4363990
TI  - [Editorial: Gas gangrene].

PMID- 4363991
TI  - [The concentration of soluble proteins and the degree of ionization of their side
      groups in several regions of the brains of rabbits following administration of
      hydrocortisone and ACTH].

PMID- 4363992
TI  - [Glycolytic processes in the livers of thyroidectomized rats].

PMID- 4363993
TI  - [Nucleic acid metabolism in hepatoma 46 and normal liver].

PMID- 4363994
TI  - [The glucose-6-phosphate dehydrogenase isoenzyme spectrum of subcellular organ
      fractions from rabbits with endogenous and exogenous hypercorticism].

PMID- 4363995
TI  - [Reiter's disease].

PMID- 4363996
TI  - [Histophysiological research of a rat's organs under the effect of Foschlor
      (author's transl)].

PMID- 4363997
TI  - [Histochemical research on the effect of administering metanabol during pregnancy
      on the differentiation of the small intestine epithelium in the embryo of a white
      rat (author's transl)].

PMID- 4363998
TI  - Dual role of calcium in steroidogenesis in the isolated adrenal cell of rat.

PMID- 4363999
TI  - A novel form of covalently bound flavin from thiamine dehydrogenase.

PMID- 4364000
TI  - Comparative study on the binding of estrogens by human and rat serum proteins in
      development.

PMID- 4364001
TI  - Antibiotic mucidin, a new antimycin A-like inhibitor of electron transport in rat
      liver mitochondria.

PMID- 4364002
TI  - The role of tryptophan in neutral fructose diphosphatase.

PMID- 4364003
TI  - A different pattern of insulin release in the perifused islets of the rabbits.

PMID- 4364004
TI  - Activity of protein-deficient 30S ribosomal subunits in elongation factor G
      dependent GTPAse.

PMID- 4364005
TI  - Sialic acid residues exposed on mammalian cell surface: the effect of adsorption
      of denatured virus particles.

PMID- 4364006
TI  - Linoleic- and linolenic acid dependency of some brain membrane-bound enzymes
      after lipid deprivation in rats.

PMID- 4364007
TI  - Insulin and non-suppressible insulin-like activity (NSILA-s): evidence for
      separate plasma membrane receptor sites.

PMID- 4364008
TI  - A recognition marker required for uptake of a lysosomal enzyme by cultured
      fibroblasts.

PMID- 4364009
TI  - Phospholipids of adrenal cortex mitochondria and the steroid hydroxylases: the
      lipid-environment of cytochrome P-450.

PMID- 4364010
TI  - Immunity to cancer: naturally occurring tumours in domestic animals as models for
      research. 2.
AB  - Part 1 of this Memorandum appeared in Vol. 49, pages 81-91. Part 2 covers
      neoplasia of the bovine urinary bladder; tumours of unknown cause (including
      melanomas, osteosarcomas, mammary tumours, lymphosarcomas, mastocytomas,
      transmissible venereal tumours, and histiocytomas); and the applications of
      animal models in studies of neoplasia. A summary of animal models is included as
      an annex.

PMID- 4364011
TI  - A fluorescent spot test for the detection of galactokinase deficiency.

PMID- 4364012
TI  - Case report No. 16942.

PMID- 4364013
TI  - [The effect of iophendylate on the concentration of formed elements, hemoglobin
      and nucleic acids in circulating blood].

PMID- 4364014
TI  - [Rearrangement of prolinol derivatives. 2. N-alkoxycarbonyl-prolinyl esters].

PMID- 4364015
TI  - Protein kinase in adipose tissue: effect of hypophysectomy.

PMID- 4364016
TI  - Renal handling of cortisol in dogs. II. Effect of ACTH on stop flow pattern.

PMID- 4364017
TI  - The cyclic AMP-mediated action of epinephrine on the activity of carbonic
      anhydrase in avian erythrocytes.

PMID- 4364018
TI  - Kidney function during anesthesia and hemorrhage.

PMID- 4364019
TI  - Repair of soft tissue injuries of the face.

PMID- 4364020
TI  - What is CWIM?

PMID- 4364021
TI  - Intracellular and extracellular nucleotides and related compounds during the
      development of Myxococcus xanthus.
AB  - Changes in nucleotide pools and extracellular nucleotides during the
      developmental cycle of the myxobacterium Myxococcus xanthus were determined using
      a high-pressure liquid chromatography nucleotide analyzer. A general increase in
      all nucleotide pools occurred during the morphological phase of glycerol
      conversion of vegetative cells to myxospores. The levels of the nucleoside
      triphosphate pools remained high as the myxospore matured and throughout
      subsequent germination. Oxidized nicotinamide adenine dinucleotide levels were
      elevated in the dormant myxospore and then declined during germination. The
      adenylate energy charge value was 0.85 +/- 0.02 for vegetative cells, germinating
      myxospores, and 6-h-old myxospores. It was interesting that the value for the so
      called dormant myxospore was the same as that characteristic of physiologically
      active cells. The germinating myxospores excreted large quantities of uracil
      along with lesser quantities of purine nucleoside monophosphates. Although the
      source of the extracellular uracil cannot be determined from these experiments,
      it may have been derived from a shift in base ratios accompanying an assumed
      ribonucleic acid turnover during germination.

PMID- 4364022
TI  - Explanation for the apparent inefficiency of reduced nicotinamide adenine
      dinucleotide in energizing amino acid transport in membrane vesicles.
AB  - Lineweaver-Burk plots of reduced nicotinamide adenine dinucleotide (NADH)
      oxidation by membrane preparations from Bacillus subtilis are biphasic, with two
      K(m) values for NADH. The higher K(m) corresponds to the only K(m) observed for
      NADH oxidation by whole cells, whereas the lower K(m) corresponds to that
      observed with open cell envelopes. Membrane preparations apparently contain a
      small fraction of open or inverted vesicles which is responsible for the low K(m)
      reaction, whereas entry of NADH into the larger portion of closed, normally
      oriented vesicles is rate limiting and responsible for the high K(m) reaction. In
      contrast, the oxidation of l-alpha-glycerol-phosphate (glycerol-P) by membrane
      preparations shows only one K(m) that corresponds to that of glycerol-P oxidation
      by whole cells or lysates. Since glycerol-P dehydrogenase (NAD independent) has
      the same K(m), this enzyme reaction rather than entry of glycerol-P into vesicles
      represents the rate-limiting step for glycerol-phosphate oxidation. The K(m) for
      amino acid uptake by vesicles in the presence of NADH corresponds to the high
      K(m) for NADH oxidation, indicating that NADH energizes transport only if it
      enters closed, normally oriented vesicles. Studies with rotenone and proteolytic
      enzymes support this interpretation. The apparent efficiency of NADH in
      energizing uptake seems to be lower than that of glycerol-P because, under the
      experimental conditions usually employed, open or inverted vesicles that do not
      participate in amino acid uptake are responsible for the major portion of NADH
      oxidation. When the results are corrected for this effect, the efficiency of NADH
      is essentially the same as that of l-alpha-glycerol-P.

PMID- 4364023
TI  - Homoserine kinase from Escherichia coli K-12: properties, inhibition by L
      threonine, and regulation of biosynthesis.
AB  - We have partially purified homoserine kinase from a genetically derepressed
      strain of Escherichia coli K-12. The optimum pH of the enzyme-substrate reaction
      was 7.8 and the K(m) values for l-homoserine and adenosine 5'-triphosphate were
      both 3 x 10(-4) M. K(+) (or NH(4) (+)) as well as Mg(2+) were required for its
      activity. The sedimentation coefficient determined by ultracentrifugation in a
      sucrose density gradient was 5.0 +/- 0.25S. l-Homoserine was an excellent
      protector against heat inactivation of homoserine kinase. l-Threonine was a
      competitive inhibitor of homoserine kinase, suggesting that end-product
      inhibition of this enzyme plays a role in vivo in the overall regulation of
      threonine biosynthesis. The specific activity of aspartokinase I-homoserine
      dehydrogenase I and of homoserine kinase showed a strong positive correlation in
      extracts from strains under widely varying conditions of genetic or physiological
      derepression; it was concluded that these two enzymes are coordinately regulated
      in E. coli K-12.

PMID- 4364024
TI  - Osmiophilic structure in pigment-producing Flavobacterium mutants.
AB  - A highly osmiophilic structure observed in all pigment-producing mutants of
      Flavobacterium examined is described. Several factors favor the possibility that
      this structure might be related to pigment synthesis or pigment accumulation.

PMID- 4364025
TI  - Lung collagen composition and synthesis. Characterization and changes with age.

PMID- 4364026
TI  - Electron paramagnetic resonance, 1-H, and 13C nuclear magnetic resonance studies
      of the interaction of manganese and bicarbonate with ribulose 1, 5-diphosphate
      carboxylase.

PMID- 4364027
TI  - Electron spin resonance studies with dioldehydrase. II. The hyperfine structure
      of proposed radical intermediates derived from isotopic substitution in 2
      chloroacetaldehyde.

PMID- 4364028
TI  - Adenylate cyclase. A new kinetic analysis of the effects of hormones and fluoride
      ion.

PMID- 4364029
TI  - Effect of uridine on de novo pyrimidine biosynthesis in rat hepatoma cells in
      culture.

PMID- 4364030
TI  - Purification and properties of electron-transferring flavoprotein from
      Peptostreptococcus elsdenii.

PMID- 4364031
TI  - Phosphorylation of acid-soluble nucleolar proteins of Novikoff hepatoma ascites
      cells in vivo.

PMID- 4364032
TI  - Properties of gonadotropin receptors in the cell membranes of bovine corpus
      luteum.

PMID- 4364033
TI  - Oxidation and reduction of soluble cytochrome c by membrane-bound oxidase and
      reductase systems.

PMID- 4364034
TI  - Regulation of the L-arabinose operon BAD in vitro.

PMID- 4364035
TI  - Surveillance of viral infections at the National Taiwan University Hospital.

PMID- 4364036
TI  - Averaged encephalic response of aphasics to linguistic and nonlinguistic auditory
      stimuli.

PMID- 4364037
TI  - Influence of stimulus level and sleep stage on the early components of the
      averaged electroencephalic response to clicks during all-night sleep.

PMID- 4364038
TI  - [Senescence and hormones].

PMID- 4364039
TI  - Stimulation of brain aromatic alkylamine N-methyltransferase activity by FAD and
      methylcobalamin.

PMID- 4364040
TI  - Cyclic nucleotide phosphodiesterase activity in rat adrenal gland zones.

PMID- 4364041
TI  - Effects of hormone treatment and age on the stimulation of rat anterior pituitary
      adenylate cyclase and cyclic adenosine 3',5' monophosphate by hypothalamic
      extract.

PMID- 4364042
TI  - Composition of myelin. Enzymes.

PMID- 4364043
TI  - [Craniotabes--induced by excessive dose of vitamin D].

PMID- 4364044
TI  - Action of two hypothalamic factors (TRH, MIF) and of angiotensin II on the
      behavioral effects of L-DOPA and 5-hydroxytryptophan in mice.

PMID- 4364045
TI  - [Characteristics of the interactions of viruses and cells in chronically infected
      cultures].

PMID- 4364046
TI  - [Pituitary gland-adrenal cortex regulation in patients with chronic kidney
      failure during longtime hemodialysis].

PMID- 4364047
TI  - [Detection of specific T-antigens and T-antibodies in artificial heterogenization
      of tumors by SV40 virus].

PMID- 4364048
TI  - [Herpetic infection of human embryo organ cultures].

PMID- 4364049
TI  - [Viral etiology of acute pneumonias in children and some of their epidemiological
      patterns in Kirghizia].

PMID- 4364050
TI  - [Renin-angiotensin system in persisting orthostatic hypotension following
      guanacline].

PMID- 4364051
TI  - [Comparative study of the characteristics of the manifestation of viral hepatitis
      in animals infected by different routes].

PMID- 4364052
TI  - [Study of the etiology of respiratory diseases].

PMID- 4364053
TI  - [Editorial: Extracellular maturation of the Rous sarcoma virus].

PMID- 4364054
TI  - Proceedings: Quantitative assay of the immunizing dose of monovalent vaccines
      against foot-and-mouth disease prepared from the virus propagated on cattle
      tongue mucosa and in culture after Frenkel.

PMID- 4364055
TI  - Proceedings: The immunizing potency of foot-and-mouth disease virus vaccines for
      swines.

PMID- 4364056
TI  - Proceedings: Isolation of various types of enteroviruses from ill children from a
      nursery school.

PMID- 4364057
TI  - Proceedings: The role of vegetables in spread of enteroviruses. I. The presence
      of poliovirus in overground parts of the plants cultivated on infected soil.

PMID- 4364058
TI  - Proceedings: Cow teat inflammation due to a poxvirus.

PMID- 4364059
TI  - [Combined corticosteroid and synthetic depot ACTH therapy in chronic obstructive
      ventilation disorders].

PMID- 4364060
TI  - A tissue culture system for studies of the regulation of ether-linked and ester
      linked aliphatic moieties in glycerolipids.

PMID- 4364061
TI  - Inhibition of subtilisin by boronic acids, potential analogs of tetrahedral
      reaction intermediates.

PMID- 4364062
TI  - The occurrence of beta-glucocerebrosidase activity in the glucocerebroside-rich
      deposits of Gaucher's disease.

PMID- 4364063
TI  - Studies on the in vitro transcription and translation of the lac operon.

PMID- 4364064
TI  - Increased response to catecholamines of the cyclic AMP system of rat pineal gland
      induced by decreased sympathetic activity.

PMID- 4364065
TI  - Characterization of the threonine-sensitive aspartokinase--homoserine
      dehydrogenase of Escherichia coli K12 by transient electric birefringence.

PMID- 4364066
TI  - [Alpha1-fetoprotein demonstration in biological fluids in primary liver cell
      carcinoma].

PMID- 4364067
TI  - Rapid purification of lactate dehydrogenase from rat liver and hepatoma: a new
      approach.

PMID- 4364068
TI  - Pseudomonas putida cytochrome P-450. Binding of a spin-labeled analog of the
      inhibitor metyrapone.

PMID- 4364069
TI  - Prolyl hydroxylase and an immunologically related protein in mammalian tissues.

PMID- 4364070
TI  - Subcellular location of rat liver calciferol-25-hydroxylase.

PMID- 4364071
TI  - Changes in membrane lipid structure of illuminated chloroplasts: studies with
      spin-labeled and freeze-fractured membranes.

PMID- 4364072
TI  - Apocrine hidrocystoma (cystademnoma).

PMID- 4364073
TI  - Clinical and metabolic effects of pentaerythritol tetranicotinate in combination
      with cholesolvin or clofibrate.

PMID- 4364074
TI  - Lipid deposits in ageing human arteries, tendons and fascia.

PMID- 4364075
TI  - [Metabolism of phospholipids of the aorta. Incorporation of (32-p) orthophosphate
      into the phospholipids of the aorta of the rat in vivo].

PMID- 4364076
TI  - Effect of the sodium salt and ethyl ester of alpha-p-chlorophenoxyisobutyric acid
      (clofibrate) on a fat-mobilizing factor in serum.

PMID- 4364077
TI  - The fatty acid composition of cholesteryl esters, phospholipids and triglycerides
      of the baboon, Papio ursinus.

PMID- 4364078
TI  - Serum lipoproteins in pigs on high-cholesterol-high-triglyceride diets.

PMID- 4364079
TI  - Composition and concentration of apolipoproteins in very-low-and low-density
      lipoproteins of normal human plasma.

PMID- 4364080
TI  - Infectious bursal disease virus: growth and characterization in cell cultures.

PMID- 4364081
TI  - Arrhenoblastoma in a chukar partridge.

PMID- 4364082
TI  - The activity of 2',3'-cyclic adenosine monophosphate 3'-phosphoesterhydrolase in
      elasmobranch and teleost brain.

PMID- 4364083
TI  - Lysosomal and mitochondrial enzymes in avian muscle.

PMID- 4364084
TI  - Vesicle ultrastructure and RNA synthesis during male meiosis of Glossina austeni
      (Diptera, Glossinidae).

PMID- 4364085
TI  - Subcellular distributions of catalase in rat skeletal muscle.

PMID- 4364086
TI  - [Letter: Climacteric disorders].

PMID- 4364087
TI  - [Preliminary results of lymphography of the human stomach: a method for
      demonstrating gastric lymph nodes by endoscopic injection of Lipiodol Ultrafluid
      (author's transl)].

PMID- 4364088
TI  - [Letter: Diagnosis of Wilm's tumor].

PMID- 4364089
TI  - Gas phase analytical methods for the study of human metabolites. Metabolic
      profiles obtained by open tubular capillary chromatography.

PMID- 4364090
TI  - [Identification of certain essential compounds in drugs by a modified
      thermofractography method (author's transl)].

PMID- 4364091
TI  - Effect of increased aortic perfusion pressure on fluorescent emission of the
      isolated rat heart.

PMID- 4364092
TI  - Inhibition of central pressor effects of agiotensin I and II.

PMID- 4364093
TI  - The after care project: a viable alternative to home care.

PMID- 4364094
TI  - [The composition, dynamics and enzymatic transformation of acid-soluble
      nucleotides, nucleosides and bases of mycelial fungi].

PMID- 4364095
TI  - [Exogenous orthophosphate regulation of phosphorus metabolism enzymes and
      polyphosphate levels in Escherichia coli K-12].

PMID- 4364096
TI  - [Phosphoribulokinase and regulation of the size of the metabolic pool of ribulose
      1,5-diphosphate by hydrogen bacteria].

PMID- 4364097
TI  - Norepinephrine--an antagonist of dibutyryl cyclic AMP in the regulation of
      narcosis in the rat.

PMID- 4364098
TI  - Cytomegalovirus antibody in uremic patients prior to renal transplantation.

PMID- 4364099
TI  - [ACTH and plasma cortisol level under function dynamic conditions in normal
      weight persons and patients with exogenous obesity].

PMID- 4364100
TI  - [Influence of ACTH and cortisol on gonadal function].

PMID- 4364101
TI  - [Determination of renal cyclic adenosine 3',5'-monophosphate excretion for
      diagnosis of primary hyperparathyroidism].

PMID- 4364102
TI  - [Catabolism of human plasma lipoproteins].

PMID- 4364103
TI  - [Clinicla findings for differentiation of Lp(a) lipoprotein].

PMID- 4364104
TI  - [Experiences with alternating corticoid therapy of chronic polyarthritis].

PMID- 4364105
TI  - [70S RNA containing particles in human leukemias].

PMID- 4364106
TI  - [Lymphocyte transformation and immunoglobulins in children with acute lymphatic
      leukemias and malignant tumors].

PMID- 4364107
TI  - [Cycl AMP influence on glucose metabolism in human blood platelets].

PMID- 4364108
TI  - [Cyclic AMP in normal and PHA stimulated lymphocytes].

PMID- 4364109
TI  - [Modification of a strain of the bovine rhinotracheitis virus and study of its
      immunogeneity].

PMID- 4364110
TI  - [Constant ratio of purine and pyrimidine bases in desoxyribonucleic acid of bull
      spermatozoa before and after deep-freezing].

PMID- 4364111
TI  - [Tryptic proteolysis in vitro of various foods].

PMID- 4364112
TI  - The influence of angiotensin II and of adrenaline on the critical opening
      pressure of vessels in forearm skin. Evidence for a qualitatively different
      response to angiotensin II in vessels of forearm skin from that in some digital
      vessels.

PMID- 4364113
TI  - A contrast in vascular reactivity between two kinds of experimental hypertension
      studied by measurements of the critical opening pressure of tail vessels in the
      conscious rat.

PMID- 4364114
TI  - Heat treatment of rat liver denosine 3':5'-monophosphate phosphodiesterase.
      Kinetic characterization of the low affinity enzyme.

PMID- 4364115
TI  - Fructose-1,6-diphosphatase from rat liver. Purification and properties.

PMID- 4364116
TI  - Specificities of rat alkaline ribonucleases and cytochemical localization of
      pancreatic-like ribonucleases.

PMID- 4364117
TI  - Nucleotide and divalent cation interactions with the (Na+ plus K+)-dependent
      ATPase.

PMID- 4364118
TI  - Dihydroxyacetone sulfate as substrate analogue for alpha-glycerol phosphate
      dehydrogenase.

PMID- 4364119
TI  - The inhibition by saccharin and cyclamate of phosphotransferase and
      phosphohydrolase activities of glucose-6-phosphatase.

PMID- 4364120
TI  - Inorganic pyrophosphate-phosphohydrolytic activity associated with human
      placental alkaline orthophosphatase. Nature of the substrate and role of
      magnesium.

PMID- 4364121
TI  - Stereochemistry of hydrogen transfer between pyridine nucleotide and some
      intermediates of cholesterol catabolism catalyzed by liver alcohol and aldehyde
      dehydrogenase.

PMID- 4364122
TI  - Studies on cyclic nucleotides in the adrenal gland. 3. Properties of cyclic AMP-
      and GMP-dependent protein kinases in the adrenal gland.

PMID- 4364123
TI  - Rabbit muscle L-glycerol-3-phosphate dehydrogenase. Substrate activity of 3,4
      dihydroxybutyl 1-phosphonate and 4-hydroxy-3-oxobutyl 1-phosphonate.

PMID- 4364124
TI  - Inhibitors of glucagon inactivation. Effect on glucagon--receptor interactions
      and glucagon-stimulated adenylate cyclase activity in liver cell membranes.

PMID- 4364125
TI  - Adenosine 3',5'-cyclic monophosphate in higher plants: assay, distribution and
      age-dependency.

PMID- 4364126
TI  - Analogs of alpha-tocopherol as inhibitors of cyclic-AMP and cyclic-GMP
      phosphodiesterases and effects of alpha-tocopherol deficiency on cyclic AMP
      controlled metabolism.

PMID- 4364127
TI  - Formation, accumulation and release of adenosine 3',5'-monophosphate induced by
      histamine in the superior cervical ganglion of the rat in vitro.

PMID- 4364128
TI  - Regulation of fructose metabolism in the perfused rat liver. Interrelation with
      inorganic phosphate, glucose, ketone body and ethanol metabolism.

PMID- 4364129
TI  - Protein-bound carbohydrate content of normal and tumorous human lung tissue.

PMID- 4364130
TI  - Alterations in adenylate cyclase activity of the rat prostate gland.

PMID- 4364131
TI  - Effects of glucagon on cyclic AMP and carbohydrate metabolism in livers from
      diabetic rats.

PMID- 4364132
TI  - Insulin receptors in murine mammary cells: comparison in pregnant and nonpregnant
      animals.

PMID- 4364133
TI  - Studies of the metabolism of asialotransferrins: potentiation of the catabolism
      of human asialotransferrin in the rabbit.

PMID- 4364134
TI  - Changes in the adenyl cyclase system of skeletal muscle of cold-acclimated rats.

PMID- 4364135
TI  - Studies on corticosterone-receptor complexes from mouse placenta.

PMID- 4364136
TI  - Biosynthesis of the diguanosine nucleotides. II. Mechanism of action of GTP:GTP
      guanylyltransferase on nucleotide metabolism in brine shrimp embryos.

PMID- 4364137
TI  - Inhibition of lipogenesis by cylic AMP without altered lipolysis.

PMID- 4364138
TI  - Effects of actinomycin D on purine ribonucleotide metabolism in Ehrlich ascites
      tumor cells in vitro.

PMID- 4364139
TI  - Pyrimidine metabolism in Pseudomonas acidovorans.

PMID- 4364140
TI  - Sequential action of cell wall hydrolases in the germination and outgrowth of
      Microsporum gypseum macroconidia.

PMID- 4364141
TI  - Characteristics of a reserve alpha-glucan from Clostridium pasteurianum.

PMID- 4364142
TI  - Morphologic and functional studies in lymph nodes regional to cancer.

PMID- 4364143
TI  - [Character and significance of the dynamics of the electrical activity of the
      neocortex and hippocampus during the paradoxical phase of sleep].

PMID- 4364144
TI  - [Spatial distribution of the reactions of the striate cortex neurons of the
      guinea pig in the projection zones of the central and peripheral areas of the
      retina].

PMID- 4364145
TI  - [Use of factor analysis for the encephalographic characterization of sleep].

PMID- 4364146
TI  - A comparison of the properties of FSH from several species as determined by a rat
      testis tubule receptor assay.

PMID- 4364147
TI  - The mechanism of frog skin lightening by acetylcholine.

PMID- 4364148
TI  - Adhesion of red cells to foreign surfaces in the presence of flow.

PMID- 4364149
TI  - [What role does the after-care clinic play?].

PMID- 4364150
TI  - [Thymic alymphoplasia without agammaglobulinemia. Nezelof syndrome].

PMID- 4364151
TI  - Extracellular lipids of Pseudomonas aeruginosa NCTC2000 obtained by n-butanol
      extraction of stationary liquid cultures.

PMID- 4364152
TI  - Studies on the degradation of poliovirus by heat.

PMID- 4364153
TI  - [Viral infections and chronic bronchopneumopathies. Isolation of cytomegalovirus
      in 2 cases].

PMID- 4364154
TI  - [Relationship between the secretion of ACTH, GH and cortisol during insulin
      hypoglycemia test in the normal and obese child].

PMID- 4364155
TI  - [Pathophysiological aspects of hypertension (author's transl)].

PMID- 4364156
TI  - [Determination of adrenocorticotropic hormone and 17-hydroxycorticosteroids in
      cancer of the corpus uteri as well as in its recurrences and metastases].

PMID- 4364157
TI  - [Intracranial hypertension syndrome in infants and children].

PMID- 4364158
TI  - Demonstration of myositis ossificans by 99mTc pyrophosphate bone scanning.

PMID- 4364159
TI  - Neurosurgical aspects of leprosy.

PMID- 4364160
TI  - Aldehyde-osmium fixation of the rat olfactory bulb: correlation between synaptic
      patterns and nature of the transmission.

PMID- 4364161
TI  - Phosphorylation in vitro of adrenal subcellular proteins by adenosine-3',5'
      monophosphate-dependent protein kinase: effect of ACTH in vivo.

PMID- 4364162
TI  - Accentuation by angiotensin II of the antidiuretic and dipsogenic responses to
      intracarotid infusions of NaCl and fructose.

PMID- 4364163
TI  - Hypercorticism in rabbits immunized against corticosteroids.

PMID- 4364164
TI  - Action of cyclic adenosine 3',5' monophosphate on protein synthesis in a
      thyroidal cell-free system. Relation to ATP and GTP.

PMID- 4364165
TI  - [Submicroscopic study of Reissner's membrane after streptomycin application].

PMID- 4364166
TI  - Gastric localization of endodermal sinus tumour.

PMID- 4364167
TI  - The fine structure of possible carcinoma-in-situ in the seminiferous tubules in
      the testis of four infertile men.

PMID- 4364168
TI  - Ultrastructural study of heterokaryons from rous rat sarcoma cells and normal
      chickens cells.

PMID- 4364169
TI  - Intracranial tumours induced in guinea pigs with Rous sarcoma virus.

PMID- 4364170
TI  - Competition between p-aminophenol, p-nitrophenol, and bilirubin for
      glucuronidation in cultures of rat hepatoma cells and homogenates of the same
      cells.

PMID- 4364171
TI  - Ultrastructural changes of rat blastocysts induced by estrogen during delayed
      implantation.

PMID- 4364172
TI  - Inhibition of vesicular stomatitis virus replication by 9-beta-D
      arabinofuranosyladenine.
AB  - 9-beta-d-Arabinofuranosyladenine (Ara-A) effectively inhibited the production of
      infectious vesicular stomatitis virus (VSV) in MDBK cells. Furthermore,
      inhibition was shown to begin as early as the first 3 hr of infection. Studies
      employing (3)H-l-leucine indicated that Ara-A did not affect protein synthesis in
      uninfected cells, although it did cause a marked stimulation of protein synthesis
      in VSV-infected cells during the log phase of the growth cycle. Puromycin, an
      inhibitor of protein synthesis, was a more effective viral inhibitor than Ara-A.
      However, the combination of Ara-A and puromycin was less effective than puromycin
      alone except when present for long time periods. Short-term labeling experiments
      with (3)H-uridine demonstrated that Ara-A depressed ribonucleic acid (RNA)
      synthesis in uninfected cells, whereas periods of stimulation and depression of
      radioisotope incorporation occurred in infected cells. The results support the
      notion that Ara-A is incorporated into RNA early during viral replication.

PMID- 4364173
TI  - Spectrophotometric method for the estimation of 6-aminopenicillanic acid.
AB  - A simple, rapid, and sensitive method is described whereby 6-aminopenicillanic
      acid can be spectrophotometrically determined in the presence of penicillins and
      their degradation products without prior separation. d-(+)-Glucosamine is used as
      reagent. The effect of such parameters as pH, temperature, and time of heating on
      the formation of the chromophore is described. The recommended range is from 25
      to 250 mug of 6-aminopenicillanic acid.

PMID- 4364174
TI  - Reversible inhibition of herpes simplex virus replication by hydroxyurea.
AB  - Hydroxyurea, at a concentration of 5 x 10(-2) M, inhibits the replication of
      herpes simplex deoxyribonucleic acid (DNA) in the nuclei of infected cells. As a
      result, the synthesis of infectious virus progeny was prevented. The presence of
      parental viral DNA genomes in inhibited cells led to the synthesis of the viral
      structural peptides. The inhibitory effect of hydroxyurea was reversible; after
      washing the cells free from hydroxyurea, virus progeny appeared after a lag of 3
      h. Upon resumption of viral DNA replication, the content of radioactive viral
      structural peptides gradually increased in parallel with the increase in mature
      virions. It is concluded that the information for the synthesis of viral
      structural peptides is transcribed from the parental DNA genomes.

PMID- 4364175
TI  - Trial of the antiviral action of isoprinosine against rhinovirus infection of
      volunteers.
AB  - Isoprinosine (NPT-10381) was given orally to a group of 22 volunteers at a daily
      dose of 6 g for 7 days; a control group of 23 volunteers received placebo.
      Volunteers were inoculated intranasally with both rhinovirus type 9 and
      rhinovirus type 31, and the clinical picture, extent of virus shedding, and
      serological responses were assessed. There was no evidence that the compound had
      useful antiviral activity under the conditions of this trial.

PMID- 4364176
TI  - Metabolism of penicillins to penicilloic acids and 6-aminopenicillanic acid in
      man and its significance in assessing penicillin absorption.
AB  - Penicillins can be metabolized to penicilloic acids in man, the extent being
      dependent on the penicillin structure. In the phenoxy penicillin series,
      phenoxymethyl penicillin was found to be particularly unstable, but the higher
      homologues were more stable. In the isoxazolyl series, oxacillin was unstable,
      and progressive insertion of halogen in the phenyl ring increased stability.
      Ampicillin and amoxycillin showed some instability, ampicillin possibly being the
      more stable. After intramuscular administration, carbenicillin was very stable in
      the body, ampicillin was fairly stable, and benzyl penicillin was unstable. It is
      important to take into account the penicilloic acid content of urine when
      estimating total absorption of a penicillin. Increased stability in the body as
      well as slower renal clearance can lead to high concentrations in the serum.
      Penicilloic acids seemed to be more slowly cleared from the body than
      penicillins. The liver is probably the site of inactivation.

PMID- 4364177
TI  - Antiviral activity of tobacco smoke condensate on encephalomyocarditis infection
      in mice.
AB  - A water-soluble nontumorigenic acidic fraction of tobacco smoke condensate of
      cigarettes has been found to have antiviral activity against encephalomyocarditis
      (EMC) virus infection in mice. The portion of lower molecular weight was
      inhibitory to the growth of EMC virus, vesicular stomatitis virus, reovirus type
      2, vaccinia virus, and poliovirus type 2, but not against adenovirus type 12, in
      KB cell cultures. The cigarette smoke agent did not induce serum interferon
      although it protected mice from EMC disease by pretreatment.

PMID- 4364178
TI  - N,N-dioctadecyl-N',N'-bis(2-hydroxyethyl) propanediamine: antiviral activity and
      interferon stimulation in mice.
AB  - CP-20,961, N,N-dioctadecyl-N', N'-bis(2-hydroxyethyl)propanediamine, is an
      antiviral drug with low acute toxicity in mice. Parenteral injection of this
      compound protected mice against lethal infections with encephalomyocarditis and
      Semliki Forest viruses and effectively suppressed pox formation by vaccinia
      infection. Maximal antiviral effects were observed when CP-20,961 was
      administered 6 to 12 h before infection. An interferon detected in plasma 12 to
      20 h after the drug was given appeared to mediate these effects. Comparison of
      the minimal effective and lethal doses in mice established a therapeutic index of
      300.

PMID- 4364179
TI  - Synergism of polymyxin and sulfonamides in L-forms of Staphylococcus aureus and
      Proteus mirabilis.
AB  - Earlier workers suggested that synergism of polymyxin and sulfonamides occurred
      because sulfonamides produced changes in the cell wall which permitted the more
      ready access of polymyxin. We tested this hypothesis by using L-forms, which lack
      cell wall. The demonstration that synergism of polymyxin and sulfonamides occurs
      in L-forms of Proteus mirabilis and Staphylococcus aureus suggested that the
      synergism is a result of some mechanism other than alterations of the cell wall.

PMID- 4364180
TI  - Double-stranded ribonucleic acid from Mengo virus: production, characterization,
      and interferon-inducing and antiviral activities in comparison with
      polyriboinosinic-polyribocytidylic acid.
AB  - Mengo virus double-stranded ribonucleic acid (dsRNA) was obtained on a semi
      industrial scale from infected cultures of BHK-21 cells grown in suspension.
      Yield of the extraction and purification operations was small (about 22 mg from
      10(11) cells in a 100-liter culture). Physicochemical characterization of this
      dsRNA gave an estimated molecular weight close to 4 x 10(6), a density of 1.59
      (similar to that of the poliovirus dsRNA), and a thermal transition midpoint of
      94 C. This product was a little more toxic for the mouse, by the intravenous
      route, than polyriboinosinic . polyribocytidylic acid (poly I:C) and strictly
      comparable in this respect to poliovirus dsRNA. The interferon-inducing capacity
      in the mouse and the antiviral activities in the mouse (infected with
      encephalomyocarditis, Semliki Forest, influenza, foot-and-mouth disease, and
      murine hepatitis viruses) and in the rabbit (Shope fibroma virus) of the
      ultraviolet light-inactivated product were practically identical, on a
      quantitative basis, with those of poly I:C. In vitro and in vivo experiments
      showed the dsRNA from Mengo virus to be slightly but significantly more resistant
      than poly I:C to the inactivating effect of human serum.

PMID- 4364181
TI  - Interaction of poliovirus-specific RNAs with HeLa cells and E. coli.

PMID- 4364182
TI  - The SV40 "S" antigen and other papovavirus-induced surface antigens.

PMID- 4364183
TI  - Alterations in bovine endothelial histidine decarboxylase activity following
      exposure to shearing stresses.

PMID- 4364184
TI  - Alcoholic steatonecrosis. II. Prospective study of prevalence of Mallory bodies
      in biopsy speciemens and comparison of severity of hepatic disease in patients
      with and without this histological feature.

PMID- 4364185
TI  - Implications of portal hepatotrophic factors in hepatology.

PMID- 4364186
TI  - Endoscopic localization of a duodenal wall tumor in Zollinger-Ellison syndrome.

PMID- 4364187
TI  - Possible involvement of cyclic AMP in regulation of masculine sexual behaviour by
      testosterone.

PMID- 4364188
TI  - Proceedings: Effect of synthetic corticotrophin analogues on plasma delta4
      androstenedione, testosterone and gonadotrophins in normal men.

PMID- 4364189
TI  - Proceedings: Cytoplasmic steroid hormone 'receptors' in reproductive organs.

PMID- 4364190
TI  - Proceedings: Effects of prostaglandin E1 and an endogenous inhibitor of
      vasopressin action on the cyclic AMP system in toad bladders.

PMID- 4364191
TI  - Proceedings: The influence of the oestrous cycle upon the energy supply for
      angiotensin-induced contractions of rat uterus and colon.

PMID- 4364192
TI  - Plasma testosterone, androstenedione and urinary 17-oxosteroids in hirsutism.

PMID- 4364193
TI  - Proceedings: Pituitary-adrenocortical function in the reserpine-treated rat.

PMID- 4364194
TI  - Proceedings: Corticosterone in the control of corticotrophin secretion in the
      rat.

PMID- 4364195
TI  - Inhibition of formation of birefringent crystals by high humidity in citrus red
      mites infected with virus.

PMID- 4364196
TI  - The development of spindle inclusions of Choristoneura fumiferana (Lepidoptera:
      Tortricidae) infected with entomopox virus.

PMID- 4364197
TI  - 67Ga-citrate imaging in untreated primary lung cancer: preliminary report of
      Cooperative Group.

PMID- 4364198
TI  - Tumor uptake of 99mTc-polyphosphate: its similarity with 87mSr-citrate and
      dissimilarity with 67Ga-citrate.

PMID- 4364199
TI  - Modification of intestinal stimulatory effects of 5-hydroxytryptamine by
      adrenergic amines, prostaglandin E1 and theophylline.

PMID- 4364200
TI  - Effects of verapamil on the short-circuit current of an epithelial membrane: the
      toad urinary bladder.

PMID- 4364201
TI  - [Mechanism of synthesis and secretion of amylase in the pancreas].

PMID- 4364202
TI  - [Non-erythropoietic component of early bilirubin in liver diseases. 1. Changes of
      early bilirubin levels in the blood and bile in acute infectious hepatitis (in
      the recovery stage) and liver cirrhosis].

PMID- 4364203
TI  - [Cardiovascular effects of glucagon].

PMID- 4364204
TI  - Lipid composition of rat superior cervical ganglion.

PMID- 4364205
TI  - In vitro desaturation of 1-14C linoleic acid in Novikoff hepatoma.

PMID- 4364206
TI  - Interrelation between silicosis and lung cancer. Preliminary report.

PMID- 4364207
TI  - Influence of citrate ions on the dissolution of silica from asbestos.

PMID- 4364208
TI  - Fluorocarbon emulsion as a blood substitute: cerebral microcirculation and
      related parameters.

PMID- 4364209
TI  - Recurrent herpes genitalis. Treatment with Mycobacterium bovis (BCG).

PMID- 4364210
TI  - Immunologic competence of the immature human fetus. Morphologic evidence from
      intrauterine Cytomegalovirus infection.

PMID- 4364211
TI  - The nature of pressor responsiveness to angiotensin II in human pregnancy.

PMID- 4364212
TI  - Relation of type 2 Herpesvirus antibodies to cervical neoplasia. Barbados, West
      Indies, 1971.

PMID- 4364213
TI  - Adenoid cystic carcinoma of the uterine cervix.

PMID- 4364214
TI  - Hypercalcemia associated with chronic renal failure: a unifying hypothesis.

PMID- 4364215
TI  - Influence of anti-inflammatory drugs on the electroencephalographic effect of
      morphine in rabbits.

PMID- 4364216
TI  - [Kidney and hypertension (author's transl)].

PMID- 4364217
TI  - [Structure and properties of hypophyseal hormones. 1. Peptide hormones of the
      pituitary gland].

PMID- 4364218
TI  - [Syndrome of total hypercorticism in a patient with pheochromoblastoma].

PMID- 4364219
TI  - [Effect of 6-methylthiouracil and cholesterol on corticosteroid biosynthesis in
      the adrenal glands of dogs].

PMID- 4364220
TI  - Development of the capillitium in Perichaena vermicularis, a plasmodial slime
      mold.

PMID- 4364221
TI  - A possible virus infection in the brown alga Pylaiella littoralis.

PMID- 4364222
TI  - [Fluorescence emission spectra and ultrastructure of plastids in the green alga
      Protosiphon botryoides treated with streptomycin (author's transl)].

PMID- 4364223
TI  - Clinical and polygraphic study of the cataplectic attacks.

PMID- 4364224
TI  - ACTH therapy in some nonhypsarrhythmic forms of epilepsy.

PMID- 4364225
TI  - Measurement of a progestational and antiandrogenic compound by a competitive
      protein binding assay.

PMID- 4364226
TI  - [Histochemical of some enzymes in the lungs of pigs with adenoviral pneumonia].

PMID- 4364227
TI  - Histochemical data on the parotid glands of the marmosets, Callithrix jacchus and
      Callithrix penicillata.

PMID- 4364228
TI  - Histochemical observations on the seminiferous epithelium of the snake testis.

PMID- 4364229
TI  - Ulastructural modifications in the keratinization process of the intermediate
      layer cells in the epidermis of Natrix natrix (L.).

PMID- 4364230
TI  - Crystalloid material in marrow macrophages of specific pathogen-free mice.

PMID- 4364231
TI  - Cytoplasmic microfilaments in the anterior lobe of the human pituitary gland.

PMID- 4364232
TI  - Effect of some chemical mutagens on proteolytic activity in Lactobacilli.

PMID- 4364233
TI  - Canine mycoplasmas II: biochemical characterization and serological
      identification.

PMID- 4364234
TI  - Rapid diagnosis by immunofluorescence of viral infections associated with the
      croup syndrome in children.

PMID- 4364235
TI  - Letter: Cyclic GMP and gastric acid secretion.

PMID- 4364236
TI  - Are cyclic AMP effects related to real physiological phenomena?

PMID- 4364237
TI  - Content of 3',5' cyclic AMP and cyclic AMP phosphodiesterase in dormant and
      activated tissues of Jerusalem artichoke tubers.

PMID- 4364238
TI  - Abnormally high rate of cyclic AMP excretion from an Escherichia coli mutant
      deficient in cyclic AMP receptor protein.

PMID- 4364239
TI  - Adenosine 3',5'-monophosphate-dependent protein kinase and amylase secretion from
      rat parotid gland.

PMID- 4364240
TI  - Regulation of prostaglandin metabolism: inhibition of 15-hydroxyprostaglandin
      dehydrogenase by thyroid hormones.

PMID- 4364241
TI  - Venom exonuclease (phosphodiesterase) immobilized on concanavalin-A-sepharose.

PMID- 4364242
TI  - Glucocorticoid tight binding in rat liver and thymus particles.

PMID- 4364243
TI  - [Studies of the variability of action of pituitary hormones. II. Tetracosactide
      and STH].

PMID- 4364244
TI  - [The diameter of some cellular strains transformed by adenoviruses and SV40
      virus].

PMID- 4364245
TI  - On the relationship between Lp(a) lipoprotein, "sinking pre-beta-lipoprotein" and
      inherited hyper-beta-lipoproteinaemia.

PMID- 4364246
TI  - Antimicrobial therapy in experimental pseudomonas infection. II.

PMID- 4364247
TI  - Thyrotropin-binding properties of isolated thyroid cells and their purified
      plasma membranes. Relation of thyrotropin-specific binding to adenylate-cyclase
      activation.

PMID- 4364248
TI  - Enzyme and enzyme fragments purification by specific immunoadsorbents.
      Application to structural studies of aspartokinase I-homoserine dehydrogenase I
      of Escherichia coli.

PMID- 4364249
TI  - A study of the density pattern of ATPase and respiratory enzymes during
      mitochondrial biogenesis of Saccharomyces cerevisiae.

PMID- 4364250
TI  - Isolation and properties of hydroxycinnamate: CoA ligase from lignifying tissue
      of Forsythia.

PMID- 4364251
TI  - Properties of soluble and bound protein kinases isolated from swine kidney.

PMID- 4364252
TI  - Metabolism of isolated kidney tubules. Regulation of pyruvate dehydrogenase by
      metabolic substrates.

PMID- 4364253
TI  - Template specificity of eucaryotic DNA-dependent RNA polymerases. Effect of DNA
      structure and integrity.

PMID- 4364254
TI  - [Antibiotics. New aspects from the viewpoint of the pharmacologist].

PMID- 4364255
TI  - Multilayering of the capillary basal lamina in the granular cell tumor. A marker
      of cellular injury.

PMID- 4364256
TI  - Herpetic esophagitis. A common cause of esophageal ulceration.

PMID- 4364257
TI  - Testing for drugs. II. Techniques and issues.

PMID- 4364258
TI  - Some international differences in histology and survival in breast cancer.

PMID- 4364259
TI  - Relationship between the sensitivity of EBV-carrying lymphoblastoid lines to
      superinfection and the inducibility of the resident viral genome.

PMID- 4364260
TI  - Histologic characteristics of breast cancer in Boston and Tokyo.

PMID- 4364261
TI  - Oncogenic activity of N-nitrosododecamethyleneimine in liver, glandular stomach
      and other tissues of NZO-B1 mice.

PMID- 4364262
TI  - Temperature-dependent alterations in 2-deoxyglucose uptake in rat cells
      transformed by a cold-sensitive murine sarcoma virus mutant.

PMID- 4364263
TI  - Fractionation of plasma membrane-associated tumor-specific antigen from an
      aminoazo dye-induced rat hepatoma.

PMID- 4364264
TI  - Distribution of basic azo-dye-binding protein in normal rat tissues and
      carcinogen-induced liver tumors.

PMID- 4364265
TI  - Immunological studies on a case of recurrent Burkitt's lymphoma during immune
      stimulant treatment.

PMID- 4364266
TI  - Isolation and characterization of a primate sarcoma virus: mechanism of rescue.

PMID- 4364267
TI  - Reversion in hybrids between SV40-transformed hamster and mouse cells.

PMID- 4364268
TI  - The horizontal development of cell-mediated tumor-specific immunity in Rous
      sarcoma virus tumorigenesis in rats.

PMID- 4364269
TI  - Aggregation of feline lymphoma cells by hyaluronic acid.

PMID- 4364270
TI  - Cell-mediated immunity and blocking factors in patients with tumours of the
      central nervous system.

PMID- 4364271
TI  - [New antigens in cells transformed by the SV40 virus. 3. Presence of an SV40
      coded antigen on the surface of different cell lines transformed by this virus
      (author's transl)].

PMID- 4364272
TI  - Cell-mediated immunity to human oral leukoplakia demonstrated by the leukocyte
      migration test.

PMID- 4364273
TI  - Effects of hypothyroidism and hyperthyroidism on dipyrone metabolism in man.

PMID- 4364274
TI  - Congenital non-progressive peripheral neuropathy with arthrogryposis multiplex.
AB  - A family is described in which a hereditary peripheral neuropathy occurs,
      inherited as an autosomal dominant character. The syndrome is present at birth
      and does not show any significant progression thereafter. Three of the cases have
      suffered from arthrogryposis multiplex congenita. A secondary myopathy is also
      present. The condition appears to be intermediary between peroneal muscular
      atrophy and Friedreich's ataxia. Appearance at birth, presence of arthrogryposis
      multiplex congenita, and the non-progressive nature separate it sharply from the
      other heredofamilial ataxias and peripheral neuropathies.

PMID- 4364275
TI  - Acidophilic adenoma of the pituitary with polyneuropathy.
AB  - An acromegalic man aged 70 developed progressive polyneuropathy affecting mainly
      the extremities. The peripheral nerves showed hypertrophic neuropathy and
      accumulation of acid mucopolysaccharides in the nerve without 'onion bulb'
      formation. The myelin showed a lamellar disintegration and vesicular formation.
      It is suggested that the association of these findings represents a pathological
      entity, acromegalic polyneuropathy.

PMID- 4364276
TI  - Electrophysiological studies of peripheral nerves in patients with organic
      mercury poisoning.
AB  - Nineteen patients with organic mercury poisoning were examined clinically and
      electrophysiological studies were carried out on their peripheral nerves. Four
      severely affected patients were disorientated, restless, and unable to speak.
      Vision was abnormal in nearly half the patients, usually consisting of gross
      constriction of visual fields with preservation of central acuity. Severe
      cerebellar abnormalities were present in most. Paraesthesiae were common. On
      sensory examination, all except three patients had one or more of the following
      abnormalities: reduced appreciation of pin prick peripherally, defective position
      sensation, abnormal two-point discrimination, astereognosis. Vibration sensation
      was normal in all. Despite these sensory findings no electrophysiological
      abnormality was demonstrated in the peripheral nerves. It is suggested that the
      sensory disturbances are predominantly or entirely due to damage to the central
      nervous system.

PMID- 4364277
TI  - In vivo lipogenesis and enzyme levels in adipose and liver tissues from pair-fed
      genetically obese and lean rats.

PMID- 4364278
TI  - The inhibition of L-3-hydroxyacyl-CoA dehydrogenase by acetoacetyl-CoA and the
      possible effect of this inhibitor on fatty acid oxidation.

PMID- 4364279
TI  - The influence of caffeine on d-amphetamine- and apomorphine-induced stereotyped
      behavior.

PMID- 4364280
TI  - Metabolism of prostaglandin A. I. The kidney cortex as a major site of PGA2
      degradation.

PMID- 4364281
TI  - Rate of inactivation of adenyl cyclase and phosphodiesterase: determinants of
      brain cyclic AMP.

PMID- 4364282
TI  - [Comparative study of certain properties of the extracellular acid RNAases of
      Penicillium claviforme].

PMID- 4364283
TI  - [Action of furfural on the cytochrome system of yeasts].

PMID- 4364284
TI  - [Use of microthin-layer chromatography for controlling the biosynthesis of
      physiologically active substances].

PMID- 4364285
TI  - [Inhibition of spore germination in actinomycetes in a constant magnetic field].

PMID- 4364286
TI  - BCG and cancer (first of two parts).

PMID- 4364287
TI  - Letter: Adenovirus type 19 keratoconjunctivitis.

PMID- 4364288
TI  - [Reversible fatigue of the postsynaptic reactions of mollusc neurons following
      strong direct hyperpolarizing stimulation].

PMID- 4364289
TI  - Sleep and serotonin in two strains of Mus musculus.

PMID- 4364290
TI  - Sleep-waking patterns and brain biogenic amine levels in cats after
      administration of 6-hydroxydopamine into the dorsolateral pontine tegmentum.

PMID- 4364291
TI  - Elicitation of water ingestion in the Mongolian gerbil (Meriones unguiculatus) by
      intracranial injections of angiotensin II and 1-norepinephrine.

PMID- 4364292
TI  - Lipid biosynthesis.

PMID- 4364293
TI  - [The effect of diet on several metabolic indices in phenylketonuria].

PMID- 4364294
TI  - [Protein concentration in winter wheat M3 following exposure to chemical
      mutagens].

PMID- 4364295
TI  - [Importance of the adrenal glands in regulating iron metabolism in the animal
      organism].

PMID- 4364296
TI  - [Carbohydrate metabolic enzyme activity and the glycogen content in the muscles
      of purebred and hybrid cattle].

PMID- 4364297
TI  - [Inhibited electrochemoluminesence as an index of the bioantioxidant activity
      during chemical hepatocarcinogenesis].

PMID- 4364298
TI  - Functional parameters in the study of metabolic regulation.

PMID- 4364299
TI  - Effect of beta receptor blockade on liver injury induced by carbon tetrachloride.

PMID- 4364300
TI  - Audiological comparison of cochlear and eighth nerve disorders.

PMID- 4364301
TI  - Cochlear and neural diseases: classification and oto-audiologic correlations.

PMID- 4364302
TI  - Association of nerve fibers and plasma cells in abnormal human nasal respiratory
      mucosa.

PMID- 4364303
TI  - Letter: Femoral neuropathy.

PMID- 4364304
TI  - Roentgenography of the ear and eye in Pyle disease.

PMID- 4364305
TI  - Idiopathic hypoglycemia in infancy. Surgical management.

PMID- 4364306
TI  - Letter: Bile duct adenomatosis of the liver.

PMID- 4364307
TI  - Theoretical view of REM sleep function: maintenance of catecholamine systems in
      the central nervous system.

PMID- 4364308
TI  - The action of D-amphetamine on spontaneous activity in the caudate nucleus and
      reticular formation of the rat.

PMID- 4364309
TI  - Family treatment within the milieu of a residential treatment center.

PMID- 4364310
TI  - An Israeli experimental group with primary school dropouts outside the school
      setting.

PMID- 4364311
TI  - Proceedings: Experimental herpes arthritis--chronicity and species specificity.

PMID- 4364312
TI  - Effect of phenobarbitone treatment on vitamin D metabolism in mammals.

PMID- 4364313
TI  - Investigation of serum lipoproteins and apoproteins in abetalipoproteinaemia.

PMID- 4364314
TI  - Melatonin and the endocrine role of the pineal organ.

PMID- 4364315
TI  - Luteinizing hormone and human chorionic gonadotropin: structure and activity.

PMID- 4364316
TI  - The effect of corticotrophine and cortisone on arylsulphatase activity in stomach
      mucosa of rats.

PMID- 4364317
TI  - [Muscle contractions on stimulation of the sensorimotor area of the cooled
      cerebral cortex].

PMID- 4364318
TI  - Platelet lipid modifications induced by fatty acids. Experimental studies and
      correlations with human neuropathology.

PMID- 4364319
TI  - Comparison of blood platelet and erythrocyte lipids in man in three age groups
      from three regions: Milan, Cincinnati and Sicily.

PMID- 4364320
TI  - Effect of lipids and hypolipaemic drugs on platelet aggregation and thrombosis.

PMID- 4364321
TI  - Effects of BCG on various facets of the immune response against polyoma tumors in
      rats.

PMID- 4364322
TI  - EBV infections in Brazil. I. Occurrence in normal persons, in lymphomas and in
      leukemias.

PMID- 4364323
TI  - Antibody to Epstein-Barr virus and cellular immunity in Hodgkin's disease and
      chronic lymphatic leukemia.

PMID- 4364324
TI  - Growth and antigenic properties of a biopsy-derived Burkitt's lymphoma in thymus
      less (nude) mice.

PMID- 4364325
TI  - Cell locomotion and contact inhibition of normal and neoplastic rat cells.

PMID- 4364326
TI  - Growth regulation and tumour formation of normal and neoplastic rat cells.

PMID- 4364327
TI  - Synthesis of murine leukemia virus in cell culture.

PMID- 4364328
TI  - Cold-sensitive mutant of Salmonella typhimurium defective in
      nucleosidediphosphokinase.
AB  - A cold-sensitive mutant of Salmonella typhimurium defective in
      nucleosidediphosphokinase (ATP:nucleosidediphosphate phosphotransferase, EC
      2.7.4.6) has been isolated and characterized. The mutant contains only 2% of the
      enzyme activity found in the parent, and the heat lability of this activity is 10
      times that from the parent at 33 C. Mutant extracts lack the ability to convert
      any of 11 nucleoside diphosphates tested to the corresponding nucleoside
      triphosphates, but the nucleosidemonophosphatase activities are normal. Although
      the nucleoside triphosphate pools of the mutant are depressed significantly at
      the restrictive temperature (20 C), they are slightly elevated at the permissive
      temperature (37 C). The levels of guanosine pentaphosphate and guanosine
      tetraphosphate are dramatically increased. Two representative enzymes of
      pyrimidine de novo synthesis, aspartic transcarbamylase and dihydroorotate
      dehydrogenase, are fully repressed at both 37 and 20 C. Intracellular pools of
      uridine diphosphate are depressed at both permissive and restrictive temperature.

PMID- 4364330
TI  - Ribonucleic acid regulation in premeabilized cells of Escherichia coli capable of
      ribonucleic acid and protein synthesis.
AB  - A cell permeabilization procedure is described that reduces viability less than
      10% and does not significantly reduce the rates of ribonucleic acid and protein
      synthesis when appropriately supplemented. Permeabilization abolishes the normal
      stringent coupling of protein and ribonucleic acid synthesis.

PMID- 4364329
TI  - Properties of a thermosensitive asporogenous filamentous mutant of Bacillus
      megaterium.
AB  - Mutant TH14 of Bacillus megaterium ATCC 19213 is thermosensitive and defective in
      cell-division septation and spore formation at the restrictive temperature (39
      C). As a consequence, the mutant forms multinucleate aseptate filaments and is
      asporogenic. The mutation does not result in any qualitative compositional
      changes in extractable membrane proteins. At the restrictive temperature, the
      mutant membrane has a reduced content of a small molecular weight protein(s). A
      membrane protein(s) with a molecular weight of nearly 80,000 appears to be
      partially derepressed in the mutant grown at the restrictive temperature. In
      addition, numerous unidentified spherical inclusions of fairly uniform size
      (diameter approximately 100 nm) are present in the cytoplasm at the restrictive
      temperature. They are especially concentrated at only one pole of each filament.
      Filamentous growth of the mutant is less sensitive to penicillin than growth in
      the rod form. Growth in either form is equally sensitive to d-cycloserine at the
      concentrations used for selection of the mutant. Temperature shift-up experiments
      suggest that one to two rounds of deoxyribonucleic acid (DNA) replication occur
      before the phenotypic expression of the mutation occurs. The septations after
      these replication events can be either two-division septations or a single
      division septation plus a subsequent sporulation septation. This conclusion,
      coupled with previously reported work, supports the hypothesis that the early
      stages of sporulation represent a modified cell division.

PMID- 4364331
TI  - Inhibition of transformation by sodium metaperiodate in Streptococcus sanguis
      (Wicky): demonstration that deoxyribonucleic acid binding sites contain amino
      acids.
AB  - Addition of sodium metaperiodate to competent Streptococcus sanguis (Wicky) cells
      at 0 or 37 C revealed that the deoxyribonucleic acid binding sites consist of
      amino acids.

PMID- 4364332
TI  - Characteristics and relationships of mercury-resistant mutants and methionine
      auxotrophs of yeast.
AB  - Approximately one-half of the mutants of Saccharomyces cerevisiae that are
      selected as resistant to methyl mercury are also found to require methionine.
      Eighty-four percent of these met mutations occur at the met15 locus, and the
      remaining 16% occur at the met2 locus. Surprisingly, the methionine-requiring
      mutants are recovered at a much higher frequency on methionineless media than on
      media supplemented with methionine. Growth patterns of the met mutants on media
      having a continuous concentration gradient of methionine and mercury compounds
      indicate that, at a critical concentration of the mercury compounds, the
      methionine requirement of certain met mutants is partially or completely
      alleviated. This was found for met2, met15, and to a lesser extent for met6, but
      not for any other methionine mutants. This loss of methionine requirement is
      produced with methyl mercury, phenyl mercury, and mercuric chloride although met2
      and met15 strains can be shown to be resistant only to methyl mercury. Other
      methionine auxotrophs are not resistant to any of the three mercury compounds.
      The met2 and met15 mutants, but not the other methionine auxotrophs, develop a
      sheen of an unidentified product when grown on media with mercuric chloride but
      not with methyl mercury or phenyl mercury. It is suggested that met2 and met15
      mutants produce a simple diffusible substance, which detoxifies methyl mercury,
      which reacts with mercuric chloride to produce a sheen, and which is the cause of
      the methionine requirement.

PMID- 4364333
TI  - Threonine locus of Escherichia coli K-12: genetic structure and evidence for an
      operon.
AB  - Three genes, thrA, thrB, and thrC, were previously defined and localized in the
      threonine locus of Escherichia coli K-12. thrA, thrB, and thrC specify the
      enzymes aspartokinase I-homoserine dehydrogenase I, homoserine kinase, and
      threonine synthetase, respectively. A complementation analysis of the threonine
      cluster using derivatives of a lambda phage carrying the threonine genes
      (lambdadthr(c)) demonstrates that: (i) thrB and thrC each consist of a single
      cistron; and (ii) thrA is composed of two cistrons, thrA(1) and thrA(2), although
      it specifies a single polypeptide chain. thrA(1) and thrA(2) correspond to
      aspartokinase I and homoserine dehydrogenase I, respectively. Their relative
      order is established. The demonstration of polar effects of mutations (nonsense
      or induced by phage Mu) in thrA and thrB is taken as evidence for the existence
      of a thrA thrB thrC operon, transcribed in this order.

PMID- 4364334
TI  - Hormonal control of lysosomal enzyme release from human neutrophils. Effects of
      autonomic agents on enzyme release, phagocytosis, and cylic nucleotide levels.
AB  - The purpose of this investigation was to examine the effects of autonomic
      neurohormones, cyclic nucleotides, and related agents on the immunologic
      discharge of lysosomal enzymes from, and phagocytosis by, purified human
      neutrophils. In order to discern the possible intracellular mechanisms by which
      certain neurohormones influence neutrophil function, the concentrations of cyclic
      AMP and cyclic GMP in neutrophils were assessed during cell contact with
      phagocytizable particles and autonomic agents. The model system employed for
      study was the interaction of purified human neutrophils with rheumatoid arthritic
      (RA) serum-treated zymosan particles at 37 degrees C in a neutral, balanced salt
      solution containing glucose. Neutrophils ingested the particles and discharged
      beta-glucuronidase but not lactate dehydrogenase activity during 30 min of
      incubation. Treatment of zymosan particles with RA serum was more effective than
      treatment with normal serum with regard to the extent of both particle uptake and
      lysosomal enzyme release. During contact of neutrophils with RA serum-treated
      zymosan particles epinephrine, isoproterenol, and cyclic AMP inhibited both
      particle ingestion and beta-glucuronidase discharge. These actions of epinephrine
      were associated with a concomitant elevation of cyclic AMP levels. In contrast to
      the actions of catecholamines and cyclic AMP, acetylcholine and cyclic GMP
      accelerated lysosomal enzyme release without affecting particle uptake. The
      actions of acetylcholine were associated with a concomitant elevation of cyclic
      GMP levels. Increases in neutrophil levels of cyclic GMP but not of cyclic AMP
      were associated also with the discharge of beta-glucuronidase provoked by
      particles in the absence of added cholinergic agents. The data suggest that the
      immunologic release of lysosomal enzymes from human neutrophils can be regulated
      by autonomic neurohormones, perhaps via the selective formation of appropriate
      nucleotides.

PMID- 4364336
TI  - 3-Substituted 5,7-dimethylpyrazolo(1,5-a)pyrimidines, 3',5'-cyclic-AMP
      phosphodiesterase inhibitors. 1.

PMID- 4364335
TI  - Autogenous immunity to endogenous RNA tumor virus. Identification of antibody
      reactivity to select viral antigens.
AB  - The viral antigenic determinants recognized in an autogenous immune response in
      mice against their endogenous C-type virus have been identified by SDS
      polyacrylamide gel electrophoresis of immune precipitates between various sera
      and H(3)-labeled intact or disrupted AKR leukemia virus. Normal B6C3F(1)
      [(C57BL/6 x C3H/Anf)F(1)] serum reacts with viral envelope antigens having mol wt
      of approximately 68,000, 43,000, and 17,000. In addition, minor reactions with
      viral antigens having mol wts of approximately 19,000 and 15,000 are
      demonstrable. The 68,000 and 43,000 mol wt antigens can be labeled with
      [(3)H]glucosamine and may correspond to the major viral envelope antigens M(2)
      and M(1), respectively. The antigens recognized by autogenous immune sera do not
      differ with respect to age of the animal, nor are they significantly different in
      sera from various strains of mice (BALB/c, C57BL/6, and C3H/Anf). These results
      suggest that the age-asociated and strain variations in the autogenous immune
      response, as determined by radioimmune precipitation assays against intact virus,
      are due to quantitative and qualitative alterations of antibody levels against
      common antigens.

PMID- 4364337
TI  - Enzymatic isotopic assay for and presence of beta-phenylethylamine in brain.

PMID- 4364338
TI  - The lipid composition of axons from bovine brain.

PMID- 4364339
TI  - Isolation and partial characterization of rat brain synaptic plasma membranes.

PMID- 4364340
TI  - Effect of neurotransmitters on phospholipid metabolism in rat cerebral-cortex
      slices: cellular and subcellular distribution.

PMID- 4364341
TI  - Mechanisms activating glycolysis in the brain in arterial hypoxia.

PMID- 4364342
TI  - The effect of porta-caval anastomosis upon the energy state and upon acid-base
      parameters of the rat brain.

PMID- 4364343
TI  - Changes in brain alcohol dehydrogenase activity during chronic ethanol ingestion
      and withdrawal.

PMID- 4364344
TI  - 2',3'-Cyclic AMP 3'-phosphohydrolase activity during Wallerian degeneration.

PMID- 4364345
TI  - Effects of neonatal hyperthyroidism on activity of cyclic AMP-dependent
      microsomal protein kinase.

PMID- 4364346
TI  - Detergent-like action of tetraphenylborate on phospholipid labelling in guinea
      pig cortex subfractions.

PMID- 4364347
TI  - The biosynthesis and concentration of galactosyl diglyceride in glial and
      neuronal enriched fractions of actively myelinating rat brain.

PMID- 4364349
TI  - Elevation of cyclic GMP levels in central nervous system by excitatory and
      inhibitory amino acids.

PMID- 4364348
TI  - Neuronal cell body enriched and glial cell enriched fractions from young and
      adult rat brains: preparation and morphological and biochemical properties.

PMID- 4364350
TI  - In vivo changes of cerebral cyclic adenosine 3',5'-monophosphate induced by
      biogenic amines: association with phosphorylase activation.

PMID- 4364351
TI  - Influence of cephalin and egg lecithin on pig heart malate dehydrogenase
      activity.

PMID- 4364353
TI  - Structure of inositol hexaphosphate--human deoxyhaemoglobin complex.

PMID- 4364352
TI  - Enzymatic acylation of histidine to mengovirus RNA.

PMID- 4364354
TI  - Expression of polyoma-induced antigens in low malignant hybrids derived from
      fusion of a polyoma-induced tumour with a fibroblast line.

PMID- 4364355
TI  - Prostaglandins and the regulation of uterine blood flow in pregnancy.

PMID- 4364356
TI  - Solubilisation of angiotensin II receptors in rabbit aortae membranes.

PMID- 4364357
TI  - Presence of HCN in chlorella vulgaris and its possible role in controlling the
      reduction of nitrate.

PMID- 4364358
TI  - Class of promotor sites for Escherichia coli DNA-dependent RNA polymerase.

PMID- 4364359
TI  - Alpha-hydrazino-ornithine blocks net synthesis of putrescine but not of RNA and
      DNA.

PMID- 4364360
TI  - Cytochrome c oxidase: some current biochemical and biophysical problems.

PMID- 4364361
TI  - Latent ganglionic infection with herpes simplex virus types 1 and 2: viral
      reactivation in vivo after neurectomy.
AB  - Inoculation of the cornea, lip, or footpad of mice with herpes simplex virus type
      1 resulted in a latent infection of the local sensory ganglia. Inoculation of the
      vagina and cervix with herpes simplex virus type 2, as well as type 1, also
      induced a latent ganglionic infection. With the use of sciatic nerve section as a
      stimulus, a reproducible model of viral reactivation in vivo was established.

PMID- 4364362
TI  - Thyroid hormone action: in vitro demonstration of putative receptors in isolated
      nuclei and soluble nuclear extracts.
AB  - Saturable binding activities for triiodothyronine were demonstrated in vitro with
      isolated nuclei and soluble nuclear extracts of rat liver, kidney, and cultured
      GH(1) cells. The binding activity can be extracted from nuclei in soluble form
      with no significant change in hormone affinity and has properties of a nonhistone
      protein.

PMID- 4364363
TI  - Blocking antibodies and enhancement.

PMID- 4364364
TI  - Invasive mole, gestational choriocarcinoma and transplantation antigens.

PMID- 4364365
TI  - Phospholipid requirements in thrombin formation.

PMID- 4364366
TI  - Effects of hypophysectomy with or without ACTH maintenance therapy on the final
      steps of aldosterone biosynthesis in the rat.

PMID- 4364367
TI  - A new in vitro method for assay of the biological activity of growth hormone.

PMID- 4364368
TI  - Serum pre-beta-1 lipoprotein fraction in coronary atherosclerosis.

PMID- 4364369
TI  - Pre-beta-1 lipoprotein and early detection of risk factors for coronary heart
      disease.

PMID- 4364370
TI  - Effect of bicarbonate and phosphate on the adrenergic receptor response in human
      adipose tissue in vitro.

PMID- 4364371
TI  - Ribonuclease T1, Structure and function.

PMID- 4364372
TI  - Normal and abnormal sexual maturation.

PMID- 4364373
TI  - Serum and liver triglycerides in malnourished Jamaican children with fatty liver.

PMID- 4364374
TI  - Papillary adenofibroma of the uterus: a benign mesodermal mixed tumor of
      Mullerian orgin.

PMID- 4364375
TI  - [Properties of erythrocyte phosphofructokinase in normal humans].

PMID- 4364376
TI  - Studies on amikhellin. I. Intercalative binding to double-stranded DNA.

PMID- 4364377
TI  - [Subcellular distribution of protein kinases stimulated by cyclic AMP and cyclic
      AMP receptor proteins in the swine thyroid].

PMID- 4364378
TI  - [Regulation of DNA synthesis in the silk gland of Bombyx mori. I. Study of
      thymidine and thymidylate-kinases of the crude soluble fraction].

PMID- 4364379
TI  - Properties of 3-aldoxime pyridine adenine dinucleotide, an NAD+ analogue.

PMID- 4364380
TI  - Effect of cyclic 3'-5' GMP on in vitro protein synthesis.

PMID- 4364381
TI  - Editorial: Guidelines on the analysis of tumour rates and death rates in
      experimental animals.

PMID- 4364382
TI  - Fibrosis as in indication of time in infiltrating breast cancer and its
      importance in prognosis.
AB  - The histological grading of tumours according to their intrinsic malignancy is
      very important in the prognosis of breast cancer but within each grade the
      ultimate prognosis depends mainly on the age of the tumours.We have shown that
      tumour fibrosis is an indication of this time factor, increasing with the age of
      the tumour. Within each grade the metastatic ratio is higher and the 5 year and
      10 year survival less with the scirrhous than with the non-scirrhous tumours. The
      establishment of axillary metastases is closely connected with both the degree of
      malignancy and the time available, the unfavourable effect upon survival being
      greater in the scirrhous than in the non-scirrhous tumours.Another consequence of
      the passage of time, as indicated by fibrosis, is the gradual diminution of
      lymphoid infiltration (LI) which is mostly present in young tumours, especially
      those of high grades. The favourable effect of LI upon survival is demonstrated
      in the non-scirrhous tumours of grade III, possibly because of its great
      intensity, but this influence upon survival is lost as fibrosis increases and the
      intensity of the reaction diminishes.

PMID- 4364383
TI  - Survival rates of lung cancer according to histological type.
AB  - The post-operative survival in 554 lung carcinomata, classified according to the
      histological type, was calculated by the actuarial method. On the whole, squamous
      cell carcinoma was the most favourable and anaplastic small cell carcinoma the
      least favourable lesion. However, in tumours smaller than 4 cm, confined to the
      lung and with negative lymph nodes (stage I), small cell carcinoma had the
      highest percentage of 5 year survivors, followed by large cell carcinoma,
      squamous cell carcinoma and adenocarcinoma. When tumours had attained a larger
      size and/or spread to neighbouring structures and regional lymph nodes (stage II
      and III), the histological type was a much more determining factor in survival,
      squamous cell carcinoma being a significantly more favourable lesion. On the
      other hand, no difference in survival in relation to the histological type was
      found when distant metastases were probably present (stage IV). It was concluded
      that in assessing the role of histopathology in the prognosis of lung cancer, the
      mutual relationship to other pathological factors must be taken into account.

PMID- 4364384
TI  - The effects of the inhalation of asbestos in rats.
AB  - Two experiments in which SPF Wistar rats were exposed by inhalation to dust
      clouds of the UICC standard reference samples for periods of between one day and
      2 years are described. All the samples of asbestos produced asbestosis which
      continued to progress after removal from exposure but only a little fibrosis was
      observed in control rats. Lung tumours, ranging in severity from adenomata to
      squamous carcinomata, were produced by all samples but in the controls there were
      only a few adenomata and none of the more serious tumours. Of the 20 tumours
      which metastasized, 16 occurred after exposure to one or other of the 2
      chrysotile samples. In addition, a total of 11 mesotheliomata occurred, 4 of
      which were with crocidolite and 4 with Canadian chrysotile. Two of the
      mesotheliomata occurred with only one day's exposure to asbestos. There was a
      positive association between asbestosis and lung tumours.

PMID- 4364385
TI  - Pulmonary blastoma.

PMID- 4364386
TI  - Management of an infected simple renal cyst by percutaneous aspiration.

PMID- 4364387
TI  - Characterization of the periodate oxidation of glycerol and related compounds,
      and application toward determination of serum triglyceride concentrations.

PMID- 4364388
TI  - Plasma corticotropin radioimmunoassay, with use of fuller's earth for extraction.

PMID- 4364389
TI  - Diabetic neuropathic cachexia.

PMID- 4364390
TI  - [Advances in the endocrinology of reproduction of domestic animals. 2.
      Neurotransmitters, neurohormones, hormones of the adenophypophysis].

PMID- 4364391
TI  - [Advances in reproduction endocrinology of domestic animals. II.
      Neurotransmitters, neurohormones, hormones of the adenohypophysis].

PMID- 4364392
TI  - A linear steady-state treatment of enzymatic chains. A mathematical model of
      glycolysis of human erythrocytes.

PMID- 4364393
TI  - RNA ligase activity in phage-infected bacteria and animal cells.

PMID- 4364394
TI  - Alteration of ribosomal proteins and functions by 2-methoxy-5-nitrotropone.

PMID- 4364395
TI  - Kinetics of the interaction between pig-plasma benzylamine oxidase and hydrazine
      derivatives.

PMID- 4364396
TI  - Affinity chromatography on immobilised adenosine 5'-monophosphate. Some kinetic
      parameters involved in the binding of group-specific enzymes.

PMID- 4364397
TI  - Studies on the quaternary structure of the threonine-sensitive aspartokinase
      homoserine dehydrogenase of Escherichia coli. A proposed subunit-interaction
      model.

PMID- 4364398
TI  - Prostaglandin induction of mitochondrial respiration and adaptive changes of
      enzymes in the perfused rat liver.

PMID- 4364399
TI  - Autoradiographic studies on the influence of ACTH and ovarian hormones on
      proliferation of epithelial cells of the mammary gland in white mice.

PMID- 4364400
TI  - Effect of bacterial enterotoxins on the gastrointestinal tract.

PMID- 4364401
TI  - [What's new in American dermatology?].

PMID- 4364402
TI  - Lipolysis in genetically obese and diabetes-prone mice.

PMID- 4364403
TI  - Electron microscopic studies on the existence of the so called "acinar-islet
      cells" in the regenerating pancreas of the rat.

PMID- 4364404
TI  - Cushing's syndrome following ectopic neoplastic production of corticotropin.
      (Report of 4 cases studied by clinical and biochemical methods, and by
      microscopic and macroscopic anatomy).

PMID- 4364405
TI  - Circadian rhythmicity of hypothalamic CRH and its central nervous regulation.

PMID- 4364406
TI  - Potentiation by antidiuretic hormone (vasopressin) of the ability of parathyroid
      hormone to stimulate the proliferation of rat thymic lymphocytes.

PMID- 4364407
TI  - Diabetes mellitus--a disorder of cellular information transmission?

PMID- 4364408
TI  - Human platelet collagenase.
AB  - The presence of proteolytic enzymes such as cathepsin and elastase in platelets
      and the important role of collagen in platelet aggregation suggested that
      collagenase might be present in platelets. Epinephrine, ADP, and collagen
      liberate collagenase from platelets in plasma as measured by the hydrolysis of
      [(14)C]glycine-labeled collagen fibrils. The collagenase activity appeared in an
      early phase of platelet aggregation and was not a part of the release reaction.
      However, only 50% of the total collagenase could be liberated by the aggregating
      agents used. Sucrose density gradient analysis of platelet homogenates using
      appropriate sub-cellular markers indicated that collagenase appeared in both the
      granule and membrane fractions. Gel-filtered platelets failed to show collagenase
      activity before exposure to aggregating agents but released more collagenolytic
      activity than was found in platelet-rich plasma. This observation was explained
      by the finding that collagenolytic activity was inhibited by normal human plasma.
      One of the inhibitors is alpha(1)-antitrypsin as demonstrated by decreased
      inhibition in plasma from a patient with homozygous alpha(1)-antitrypsin
      deficiency. Platelet collagenase activity could also be demonstrated by its
      ability to decrease the viscosity of collagen solutions and to produce collagen
      fragments similar to those produced by other mammalian collagenases on disk gel
      electrophoresis. The observation that partially purified platelet collagenase
      could destroy the platelet-aggregating activity of collagen suggests that the
      enzyme might function in a negative feedback mechanism limiting thrombus
      formation.

PMID- 4364409
TI  - Biological defense mechanisms. The effect of bacteria and serum on superoxide
      production by granulocytes.
AB  - We previously reported that granulocytes are able to produce superoxide (O(2) (
      )), a highly reactive compound formed by the one-electron reduction of oxygen.
      The demonstration of O(2) (-) production was based on the observation that the
      reduction of extra-cellular cytochrome c by granulocytes was greatly diminished
      by superoxide dismutase, an enzyme catalyzing the conversion of O(2) (-) to
      hydrogen peroxide and oxygen. In the present report, studies concerning the
      effect of bacteria and serum on O(2) (-)-dependent cytochrome c reduction by
      granulocytes are described.In the absence of bacteria, the O(2) (-)-dependent
      reduction of extracellular cytochrome c by granulocytes under optimal assay
      conditions amounted to 9.2+/-2.8 SD nmol/3 x 10(6) cells/20 min. When bacteria
      (100 organisms/cell) were present, the O(2) (-)-dependent cytochrome c reduction
      under otherwise similar conditions increased by a factor of nearly four (34.5+/
      9.4). There was no effect of albumin or catalase on cytochrome c reduction, and
      boiled dismutase had only a small effect. Omission of granulocytes or
      substitution of live cells by cells by cells killed by heat abolished O(2) (-)
      dependent cytochrome c reduction. Bacteria killed by autoclaving were almost as
      effective as live bacteria in stimulating granulocyte O(2) (-) production.
      Measurements of particle uptake and O(2) uptake by granulocytes indicated that
      superoxide dismutase did not affect granulocyte metabolism nonspecifically,
      supporting the conclusion that the diminution of cytochrome c reduction in the
      presence of dismutase was due to the destruction of O(2) (-) by this enzyme.
      Stimulation of O(2) (-) production by bacteria was strongly dependent on the
      presence of serum in the incubation mixture. Serum heated to 56 degrees C for 45
      min was as effective as unheated serum in stimulating O(2) (-) production in the
      presence of bacteria, but boiled serum had no effect. Other experiments suggested
      that incubation of bacteria with serum resulted in the release of a
      nonparticulate heat-labile substance capable of stimulating O(2) (-) production
      in the absence of bacteria. Certain characteristics of the O(2) (-)-dependent
      cytochrome c reduction by granulocytes were studied, including the dependence of
      this process on granulocyte, cytochrome c, and bacterial concentrations. In
      addition, O(2) (-)-dependent cytochrome c reduction was followed as a function of
      time. A constant rate was found with resting granulocytes. With bacteria the time
      course was more complex. A well-defined lag was followed by a fairly brief period
      of extremely vigorous cytochrome c reduction. During this period, the maximum
      rate of cytochrome c reduction exceeded the rate observed in the absence of
      bacteria by a factor of 12. The rate then decreased until by 40 min, it had
      slowed to the rate observed in the absence of bacteria. From the above results,
      it was concluded that the exposure of the granulocyte to bacteria plus serum
      initiates a process in which a defined quantity of O(2) (-) is formed in a rapid
      burst lasting 20-30 min. It is conceivable that the O(2) (-) generated by this
      process may be involved in the killing of bacteria by the granulocytes.

PMID- 4364410
TI  - Immunochemical localization of parathyroid hormone in cancer tissue from patients
      with ectopic hyperparathyroidism.
AB  - Immunoreactive parathyroid hormone (PTH) in nonparathyroid malignant tumors
      associated with hypercalcemia and hypophosphatemia in the absence of demonstrable
      bone metastases was determined by radioimmunoassay and immunofluorescent
      techniques. Six of seven tumors contained material with immunological cross
      reactivity to bovine PTH by radioimmunoassay and immunofluorescence. The
      intensity of the immunofluorescent stain varied considerably in the different
      tumors. From 15 to 90% of neoplastic cells were stained specifically with
      fluorescein-labeled anti-PTH. In contrast, normal parathyroid glands and
      parathyroid adenomas showed uniform distribution of immunofluorescence in all
      parenchymal cells. In one malignant tumor, PTH was localized also by
      immunoautoradiography. In every case PTH was detected only in the cytoplasm of
      parenchymal cells. One patient lacked detectable PTH in his tumor, yet showed
      regression of the hypercalcemia to normal values after removal of large masses of
      neoplastic tissue and recurrence of hypercalcemia when new growth
      occurred.Dilutional radioimmunoassay curves of nonparathyroid malignant tumors
      were in most cases different from those obtained with extracts of normal
      parathyroid glands and parathyroid adenomas. Although both nonparathyroid
      neoplasmas and parathyroid extracts demonstrated immunoheterogeneity by gel
      filtration, greater heterogeneity was found in nonparathyroid malignant tumors.
      In those tumors in which immunological cross-reactivity to PTH was detected, the
      capability of secreting PTH may be restricted to derepressed cell clones amidst
      other neoplastic cells, whereas the greater heterogeneity of ectopic PTH may
      reflect hormone cleavage by proteolytic enzymes in the tumor that is less
      specific than the Pro-PTH cleaving enzyme in the parathyroids.

PMID- 4364411
TI  - The effect of ethidium bromide on the membrane glycopeptides in control and virus
      transformed cells.

PMID- 4364412
TI  - The effect of parathyroid hormone and thyrocalcitonin on the accumulation of
      cyclic adenosine 3':5'-monophosphate in freshly isolated bone cells.

PMID- 4364413
TI  - Receptor-binding affinities and biological activities of analogs of thyrotropin
      releasing hormone in prolactin-producing pituitary cells in culture.

PMID- 4364414
TI  - The effects of epinephrine and prostaglandin E-1 on cyclic adenosine 3':5'
      monophosphate levels in WI-38 fibroblasts.

PMID- 4364415
TI  - Purification and kinetic characterization of a monovalent cation-activated
      glycerol dehydrogenase from Aerobacter aerogenes.

PMID- 4364416
TI  - Electron paramagnetic resonance studies of cobalt-copper bovine superoxide
      dismutase.

PMID- 4364417
TI  - Iron, an essential component of lipoxygenase.

PMID- 4364418
TI  - Magnetic resonance and kinetic studies of the mechanism of sodium and potassium
      ion-activated adenosine triphosphatase.

PMID- 4364419
TI  - The subcellular localization of glutaminase isoenzymes in rat kidney cortex.

PMID- 4364420
TI  - Regulation of renal ammoniagenesis. Subcellular localization of rat kidney
      glutaminase isoenzymes.

PMID- 4364421
TI  - Two nucleid acid-dependent nucleoside triphosphate phosphohydrolases from
      vaccinia virus. Purification and characterization.

PMID- 4364422
TI  - Two nucleic acid-dependent nucleoside triphosphate phosphohydrolases from
      vaccinia virus. Nucleotide substrate and polynucleotide cofactor specificities.

PMID- 4364423
TI  - Single-stranded deoxyribonucleic acid-specific nuclease from vaccinia virus.
      Endonucleolytic and exonucleolytic activities.

PMID- 4364424
TI  - Conformational transition in polypeptide elongation factor Tu as revealed by
      electron spin resonance.

PMID- 4364425
TI  - Nonessentiality of the active sulfhydryl group of rabbit muscle creatine kinase.

PMID- 4364426
TI  - Photoaffinity labeling with cyclic nucleotides.

PMID- 4364427
TI  - Treatment of renal osteodystrophy with calciferol (vitamin D) and related
      steroids.

PMID- 4364428
TI  - Disordered divalent ion metabolism in kidney disease: comments on pathogenesis
      and treatment.

PMID- 4364429
TI  - The kidney as an endocrine organ involved in calcium homeostasis.

PMID- 4364430
TI  - [In sulfure diabolus: in sulfur there sticks the devil].

PMID- 4364431
TI  - [Clinical experience with betain citrate (author's transl)].

PMID- 4364432
TI  - [Effects of a new vasoactive substance on renal hemodynamics].

PMID- 4364433
TI  - Presence of a large poly(rC) tract within the RNA of encephalomyocarditis virus.

PMID- 4364434
TI  - Fucosylglycolipids in cells transformed by a temperature-sensitive mutant of
      murine sarcoma virus.

PMID- 4364435
TI  - Carbohydrate groups in the major glycoprotein of Rous sarcoma virus.

PMID- 4364436
TI  - Parathormone, cyclic AMP and neonatal kidneys.

PMID- 4364437
TI  - Regulation of cell growth by cyclic AMP.

PMID- 4364438
TI  - Cytomegalovirus infections in New York State.

PMID- 4364439
TI  - [Juvenile fibromas].

PMID- 4364440
TI  - Ultrastructural and functional relationships of some human endocrine tumors.

PMID- 4364441
TI  - [Biological consequences of enzymatic modifications of proteins (author's
      transl)].

PMID- 4364443
TI  - [Discitis following operations for lumbar disc prolapse (Close space infection)].

PMID- 4364442
TI  - Positive control of transformed phenotype in hybrids between SV40-transformed and
      normal human cells.
AB  - Somatic cell hybrids have been obtained between SV40-transformed Lesch-Nyhan
      fibroblasts, which are deficient in hypoxanthine-guanine
      phosphoribosyltransferase (HGPRT) and display glucose-6-phosphate dehydrogenase A
      (G6PD-A) activity, and late-passage HGPRT-positive W138 human embryo fibroblasts,
      which display G6PD-B activity. The human-human hybrid clones, which display G6PD
      A and G6PD-B and heteropolymers of the two enzyme forms, have the same growth
      characteristic as the SV40-transformed parental cells and behave as continuous
      cell lines. The SV40 tumor antigen, the gene for which has been assigned to human
      chromosome 7, is present in all clones examined.

PMID- 4364444
TI  - [Some clinical syndromes associated with hormonally-active tumors of pancreatic
      islets derived from non-insulin-producing cells].

PMID- 4364445
TI  - [Lymphocytosis-stimulating and type-specific serological activity of B.
      pertussis].

PMID- 4364446
TI  - [Characteristics of the serological properties of Bordetella pertussis variants
      with defective cell walls].

PMID- 4364447
TI  - [Ultrastructure of L forms. I. Mycobacterium tuberculosis].

PMID- 4364448
TI  - Conversion of angiotensin I in pulmonary and systemic vascular beds of children.

PMID- 4364449
TI  - On the mechanism of the enhancement by smooth muscle stimulants of the motor
      responses of the guinea-pig vas deferens to nerve stimulation.

PMID- 4364450
TI  - Activities of rat muscle enzymes after acute exercise.

PMID- 4364451
TI  - Differences in recruitment order and discharge pattern of motor units in the
      early and late flexion reflex components in man.

PMID- 4364453
TI  - Stimulation of adenosine 3,5-monophosphate formation in mast cells by 5
      hydroxytryptamine and guanethidine.

PMID- 4364452
TI  - The effect of dopa on the spinal cord. 8. Presynaptic and "remote" inhibition of
      transmission from Ia afferents to alpha motoneurones.

PMID- 4364454
TI  - Carcinogenic response of brood sows fed aflatoxin for 28 to 30 months.

PMID- 4364455
TI  - Infectivity of bovine C- type (leukemia) virus for sheep and goats.

PMID- 4364456
TI  - Genital disease in dogs caused by canine herpesvirus.

PMID- 4364457
TI  - Study of the use of evoked cortical activity for clinical evaluation of spinal
      cord sensory transmission.

PMID- 4364458
TI  - Lesions in nervous tissue of owl monkeys experimentally infected with herpesvirus
      T.

PMID- 4364459
TI  - Antigenic comparisons and serologic survey of equine adenoviruses.

PMID- 4364460
TI  - Phagocytosis of Babesia canis by neutrophils in peripheral circulation.

PMID- 4364461
TI  - Reduction of mercury to the elemental state by a yeast.
AB  - A yeast of the genus Cryptococcus has been isolated from a stream and was shown
      to be capable of reducing mercury to the elemental state. The organism grows in
      Wickerham broth supplemented with high concentrations of mercury (II) chloride
      (180 mg of mercury per liter) and will metabolize [(14)C]glucose in this medium
      as do cells in the absence of mercury. Mercury was associated with the cell wall
      and membrane, and in vacuoles within the cytoplasm.

PMID- 4364462
TI  - The plaque-antiserum method: an assay of virus infectivity and an experimental
      model of virus infection.
AB  - Areas of cytopathic effect can be circumscribed in cell monolayers by adding
      antiserum to the liquid nutrient medium after adsorption of virus. This procedure
      represents a simple and reliable tool for the titration of virus infectivity and
      provides an experimental model for studying some aspects of virus infection.

PMID- 4364463
TI  - Environmental factors influencing isolation of enteroviruses from polluted
      surface waters.
AB  - The influence of water quality upon the concentration of virus on location was
      assessed in field studies conducted in the Houston ship channel, Galveston Bay,
      and Houston waste treatment plants. Clarification of polluted surface waters was
      accomplished with minimal loss of virus. Virus from clarified sewage effluents
      and saline waters was then adsorbed and concentrated on textile and membrane
      filter surfaces. Direct measurements of virus from large volumes of polluted
      surface waters under existing field conditions were then made using the virus
      concentrator equipment.

PMID- 4364464
TI  - Concentration of oncogenic herpesviruses by methyl alcohol precipitation.
AB  - Oncogenic herpesviruses, like many other viruses, can be concentrated effectively
      from large volumes of culture fluids by precipitation with methanol with good
      recovery of infectivity.

PMID- 4364465
TI  - Hepatitis B (Australia) antigen--current clinical and epidemiological concepts.

PMID- 4364466
TI  - Electrophoretic characterization of human phosphoribosylpyrophosphate synthetase.

PMID- 4364467
TI  - Pyruvate carboxylase in human liver. Apparent loss of a component of catalytic
      activity in a form of lactic acidosis with hypoglycemia.

PMID- 4364468
TI  - Metabolite levels reflecting changes in liver energy metabolism during the
      neonatal period.

PMID- 4364469
TI  - Influence of asphyxia and of dexamethasone on ATP concentrations in the immature
      rat brain.

PMID- 4364471
TI  - Acetylcholine sensitivity of the chick fast muscle after cross-union with the
      slow muscle nerve.

PMID- 4364470
TI  - Cytoplasmic solvent structure of single barnacle muscle cells studied by electron
      spin resonance.
AB  - A free radical probe was introduced into single barnacle muscle cells, and its
      freedom of motion inferred from the spin resonance spectra. The probe reported an
      average local viscosity of 5-10 cp compared with 1 cp for pure water. From a
      comparison of the temperature dependence of the probe's tumbling rate in model
      aqueous systems and in the muscle we concluded that in the muscle the probe was
      undergoing fast exchange between sites of different mobility. Thus 10 cp must be
      taken as an upper limit for the viscosity of most cell water.

PMID- 4364472
TI  - Modulation of synaptic transmission in cat's superior colliculus by saccadic eye
      movements.

PMID- 4364473
TI  - Common synaptic effects of pentylenetetrazol and penicillin.

PMID- 4364474
TI  - Stimulation- and calcium-dependence of vesicle attachment sites in the
      presynaptic membrane: a freeze-cleave study on the lamprey spinal cord.

PMID- 4364475
TI  - Ascending monoamine-containing fiber pathways related to intracranial self
      stimulation: histochemical fluorescence study.

PMID- 4364476
TI  - The action of norepinephrine in the rat hippocampus. I. Iontophoretic studies.

PMID- 4364477
TI  - The action of norepinephrine in the rat hippocampus. II. Activation of the input
      pathway.

PMID- 4364478
TI  - [New data on the role of taurine as a transmitting-inhibitor in the chick
      retina].

PMID- 4364479
TI  - [Effect of various androgens on carcinogenesis of in the rat liver induced by
      para-dimethylaminoazobenzene (DAB)].

PMID- 4364480
TI  - [Insulinoma].

PMID- 4364481
TI  - [Carcinoid].

PMID- 4364482
TI  - Histochemical studies on the effect of sodium fluoride on metabolism in
      Purkinje's cells.

PMID- 4364483
TI  - The effect of oxytocin on the oxidoreductive activity and spermatogenesis in the
      rabbit testicle.

PMID- 4364484
TI  - [Changes due to pancreatic cysts seen on retrograde endoscopic choledocho
      pancreaticograms (author's transl)].

PMID- 4364485
TI  - [Changes on retrograde cholangiograms in primary biliary cirrhosis of the liver
      (author's transl)].

PMID- 4364486
TI  - [The value of conventional radiographic methods in the differential diagnosis of
      congenital cardiac defects during the first month of life (author's transl)].

PMID- 4364487
TI  - [Pulmonary vasularisation in isolated left heart syndromes in neonates (author's
      transl)].

PMID- 4364488
TI  - [Experience with a satisfactory condenser discharge unit (Condix) in a neonatal
      department (author's transl)].

PMID- 4364489
TI  - [Filling of Lieberkuhn's crypts of the colon during contrast examination. A
      contribution to the differential diagnosis of colitis (author's transl)].

PMID- 4364490
TI  - [Pneumo-encephalographic findings in children with microcephaly (author's
      transl)].

PMID- 4364491
TI  - [Tomography for malformations of the ear. Guides for its practical use (author's
      transl)].

PMID- 4364492
TI  - [Craniometric investigations of the normal growth rate of the intracranial space
      in the first three years of life (author's transl)].

PMID- 4364493
TI  - [Radiological aspects of umbilical vein catheterization (author's transl)].

PMID- 4364494
TI  - [The Cronkhite-Canada syndrome (author's transl)].

PMID- 4364495
TI  - [Abnormal ureteric motility (author's transl)].

PMID- 4364496
TI  - [Estimation of renal filtration fraction by a simultaneous double radionucleide
      clearance technique (author's transl)].

PMID- 4364498
TI  - [Cisternography with 111Indium-HSA (author's transl)].

PMID- 4364497
TI  - [Differentiation of renal drainage abnormalities by functional scintigraphy
      (author's transl)].

PMID- 4364499
TI  - [Roentgen-cine-densitometric measurements with computer analysis (author's
      transl)].

PMID- 4364500
TI  - [Practical usefulness of an x-ray microfilming system. Association study of x-ray
      film documentation and archives on fluorographic format 100x100 mm].

PMID- 4364501
TI  - [Metastasizing psammocarcinoma ovary].

PMID- 4364502
TI  - [Unusual course of a melanoma].

PMID- 4364503
TI  - [Bilateral parasternal diaphragmatic hernia with thyroid gland aplasia in an
      infant].

PMID- 4364504
TI  - [Roentgen symptoms of Candida-esophagitis].

PMID- 4364505
TI  - Action of Escherichia coli enterotoxin: adenylate cyclase behavior of intestinal
      epithelial cells in culture.
AB  - Heat-labile enterotoxin preparations obtained from two enteropathogenic strains
      of Escherichia coli of porcine and human origin were shown to stimulate adenylate
      cyclase activity of human embryonic intestinal epithelial cells in culture.
      Comparable results were also obtained when cholera toxin was used. The degree of
      enzyme stimulation was proportional to the concentration of enterotoxin. Similar
      preparations from two strains of non-enterotoxigenic E. coli had no effect on
      adenylate cyclase activity. Cells exposed to enterotoxin could be washed after 1
      min of contact time without altering the subsequent course of maximum adenylate
      cyclase activity, which was maintained for at least 18 h at 37 C. During long
      periods (18 h) of tissue culture incubation, the determination of adenylate
      cyclase activity was 200- to 300-fold more sensitive than quantitating fluid
      accumulation in the adult rabbit ileal loop model. Decreasing the incubation time
      appreciably reduced the sensitivity of the epithelial cells to enterotoxin. E.
      coli enterotoxin is an effective activator of nonintestinal adenylate cyclase
      systems. Treatment of KB and HEp-2 cell lines with enterotoxin also resulted in
      significant enzyme stimulation. The intestinal epithelial cell tissue culture
      model provides a sensitive homogenous biological system for studying the response
      of intestinal adenylate cyclase to enterotoxin while eliminating the numerous
      cellular and tissue components present in the ligated ileal loop model.

PMID- 4364506
TI  - Replication of Marek's disease virus in cell cultures derived from genetically
      resistant chickens.
AB  - Various parameters of replication of Marek's disease virus (MDV) were studied in
      cells derived from genetically resistant (line 6) and susceptible (line 7)
      chickens. Cell-free and cell-associated preparations of three strains of
      pathogenic MDV (JM, GA, and Id-1) replicated equally well in cells of resistant
      and susceptible chickens. There were no demonstrable differences between the two
      genetic sources of cells for the chronological appearance and type of cytopathic
      effects and for the type of virus-induced antigens detectable by
      immunofluorescent and agar-gel precipitin tests. MDV propagated for about 4 weeks
      in cells of resistant line 6 chickens remained nonvirulent for line 6 and fully
      virulent for line 7 chickens. The lack of expression of genetic resistance to
      Marek's disease at cellular level contrasts the infection mechanisms of MDV from
      those of viruses associated with lymphoid leukosis in chickens.

PMID- 4364507
TI  - [Antibodies against cytomegalovirus in hepatitis related to Australia antigen and
      other criteria of serum hepatitis (author's transl)].

PMID- 4364508
TI  - Synthesis and biological activity of some 8-substituted seleno cyclic nucleotides
      and related compounds.

PMID- 4364509
TI  - Synthesis of analogs of (8-isoleucine)angiotensin II with variations in position
      1.

PMID- 4364510
TI  - Synthesis of some trinucleoside monophosphates of biological interest.

PMID- 4364511
TI  - The pathology of the human muscle spindle: effect of denervation.

PMID- 4364512
TI  - [Malignant mixed tumor of the tongue].

PMID- 4364513
TI  - [Interval of radiosensitivity as a basis of therapeutic irradiation of malignant
      tumors].

PMID- 4364514
TI  - A thin-layer chromatographic procedure for the separation of aspirin, cocaine,
      caffeine, codeine, heroin, 6-monoacetyl morphine, and morphine.

PMID- 4364515
TI  - [BR 750 (2,6-dichloro-benzilidene amino guanidine acetate), skeletal musculature
      and neuromuscular transmission].

PMID- 4364516
TI  - [Control of thyrotrophic and corticotrophic functions in acromegaly].

PMID- 4364517
TI  - [Acromegaly syndrome: choice of surgical technic].

PMID- 4364518
TI  - [Large tumor of the glomus jugulare: combined oto-neuro-surgical approach].

PMID- 4364519
TI  - [Serum proteins in healthy and VHS affected rainbow trout (author's transl)].

PMID- 4364520
TI  - [Cytomegalic virus infection in an infant with jaundice confirmed by virological
      methods].

PMID- 4364521
TI  - Oligonucleotide photoproducts formed by photolysis of polyribobromouridylic acid.

PMID- 4364522
TI  - Photochemistry of biological molecules. IV. Gaseous products from the photolysis
      of alanine peptides in the solid state.

PMID- 4364523
TI  - The phosphorescent triplet state of some hydroxycoumarins.

PMID- 4364524
TI  - The egg yolk very low density lipoproteins of fresh and stored shell eggs.

PMID- 4364525
TI  - Synthesis of simian virus 40 DNA in isolated nuclei.
AB  - Nuclei isolated from African green monkey kidney cells infected with simian virus
      40 at different times after infection maintain in vitro the same temporal
      sequence of host and viral DNA synthesis as that seen in intact cells. The viral
      DNA synthesized by the nuclei of cells previously infected for 32-35 hr was
      characterized by centrifugation through neutral and alkaline sucrose gradients,
      and by isopycnic banding in a propidium iodide-cesium chloride gradient. DNA
      synthesis in this system is maintained for only 4-5 min. Neutral sucrose gradient
      analysis showed that most of the radioactivity is associated with the replicative
      intermediate of simian virus 40 DNA and the rest sediments at 5-7 S. Alkaline
      gradient analysis showed that 50-60% of the radioactivity sediments as 3-7S
      fragments, and the rest between 7 and 16 S. Pulsechase experiments showed that in
      this system 3-7S fragments do not mature into long chains. A model is presented
      to explain the failure of these fragments to join into long chains in this in
      vitro nuclear system.

PMID- 4364526
TI  - Genetic control of melanization: isolation and analysis of amelanotic variants
      from cultured melanotic melanoma cells.
AB  - MELANOMA CELLS EXPRESS A PHENOTYPE THAT IS EASY TO RECOGNIZE: the synthesis of
      melanin. We used this marker to isolate clones of amelanotic variants from large
      populations of wild-type melanotic clones. Cloudman mouse melanoma (S91, clone M
      3, CCL 53.1) was chosen as the parental line because the cells are highly
      pigmented, grow well as clones in soft agar, and fuse readily with Sendai virus.
      Subclones (10(7)) of this line were screened without prior mutagenesis, and nine
      amelanotic variants were isolated. The mutagen ethylmethanesulfonate increased
      the frequency of variants by three to four orders of magnitude. Wild-type cells
      had both basal and melanocyte stimulating hormone-inducible tyrosinase
      activities. The four amelanotic variants that we have examined to date all
      behaved similarly: they lost basal tyrosinase (EC 1.14.18.1; monophenol
      monooxygenase) activity but retained melanocyte stimulating hormone-inducible
      activity; they contained Stage-II melanosomes but no melanized melanosomes; they
      exhibited growth characteristics similar to those of wild-type cells in culture
      but produced fewer tumors in mice.

PMID- 4364527
TI  - Octopamine- and serotonin-stimulated phosphorylation of specific protein in the
      abdominal ganglion of Aplysia californica.
AB  - Phosphorylation of a protein (or proteins) of molecular weight 120,000 in the
      Aplysia abdominal ganglion, as measured by incorporation of [(32)P] or
      [(33)P]sodium phosphate in vitro followed by separation of the phosphoproteins on
      sodium dodecyl sulfate-polyacrylamide gels, was specifically stimulated by
      incubation in the presence of the putative neurotransmitters octopamine or
      serotonin. The stimulatory effect of octopamine and serotonin was inhibited by
      phentolamine and methysergide, respectively, and was mimicked by incubation in
      the presence of dibutyryl cyclic AMP. Label-chase experiments indicated that the
      difference between control and octopamine-treated ganglia persists for several
      hours after removal of the drug from the incubation medium. This result suggests
      that neurotransmitters may produce relatively long-lasting changes in a
      phosphoprotein in the ganglion, perhaps in postsynaptic cells.

PMID- 4364528
TI  - Relationship of a proton gradient to the active transport of proline with
      membrane vesicles from Mycobacterium phlei.
AB  - Electron transport particles prepared from Mycobacterium phlei were depleted of
      bound coupling factors by washing with water in the absence of inorganic ions.
      The depleted electron transport particles were void of latent ATPase activity and
      were capable of oxidation, but were unable to support coupled phosphorylation.
      Nevertheless, the depleted electron transport particles were capable of substrate
      induced active transport of proline. Changes in pH in response to substrate
      oxidation were measured in normal and depleted electron particles with bromthymol
      blue. A bromthymol blue response upon substrate oxidation was not observed with
      depleted electron transport particles. The level of oxidative phosphorylation
      with succinate or NADH oxidation was not reduced in the presence of proline, and
      proline did not have an effect upon the proton gradients formed by the oxidation
      of either succinate or NADH.

PMID- 4364529
TI  - Cell-free transcription of mammalian chromatin: transcription of globin messenger
      RNA sequences from bone-marrow chromatin with mammalian RNA polymerase.
AB  - A mammalian cell-free transcriptional system was developed in which mammalian RNA
      polymerase synthesizes globin messenger RNA sequences from bone-marrow chromatin.
      The messenger RNA sequences are detected by measurement of the ability of the
      transcribed RNA to hybridize with globin complementary DNA. The globin
      complementary DNA is synthesized by the enzyme from avian myeloblastosis virus,
      RNA-directed DNA polymerase, with purified globin messenger RNA as template. The
      specificity of the globin complementary DNA in annealing reactions was verified
      by preparing DNA complementary to liver messenger RNA and showing that the globin
      and liver complementary DNAs are specific for their own messenger RNAs. Both DNA
      dependent RNA polymerase II from sheep liver and RNA polymerase from Escherichia
      coli can transcribe globin messenger RNA sequences from rabbit bone-marrow
      chromatin; however, the mammalian enzyme appears to be more specific in that
      globin gene sequences represent a higher proportion of the RNA synthesized.
      Neither polymerase can transcribe globin messenger RNA sequences from rabbit
      liver chromatin. This cell-free assay system should be useful in searching for
      mammalian transcriptional regulatory factors.

PMID- 4364530
TI  - Simian virus 40 DNA sequences in DNA of healthy adult mice derived from
      preimplantation blastocysts injected with viral DNA.
AB  - Explanted mouse blastocysts were microinjected in the blastocoel cavity with
      simian virus 40 (SV40) viral DNA. After surgical transfer to the uteri of
      pseudopregnant surrogate mothers, approximately 40% of the blastocysts developed
      to term and became healthy adults without apparent tumors at 1 year of age.
      Molecular hybridization tests for the presence of SV40-specific DNA sequences
      were conducted on DNA extracted from various organs of these animals. Between 0.5
      and 13 SV40 genome equivalents per diploid mouse DNA value were found in some
      organs of approximately 40% of the adult survivors; this represents a substantial
      augmentation of the amount administered per embryo. The results are consistent
      with the working hypothesis that the SV40 DNA may have been integrated into the
      host genome; alternatively, the viral DNA may have replicated as an
      extrachromosomal entity or by lytic infection in a few permissive cells.
      Persistence of the viral DNA from preimplantation stages to adult life may thus
      provide a new tool for experimental investigation of vertical transmission and
      expression of tumor viruses.

PMID- 4364531
TI  - Viral DNA-RNA hybrids in cells infected with simian virus: the simian virus 40
      transcriptional intermediates.
AB  - Brief labeling of cells infected with simian virus 40 with tritiated uridine
      resulted in the incorporation of part of the label into material that was soluble
      in 1 M NaCl and sensitive to KOH, with a buoyant density close to that of DNA.
      The properties of this material suggest that it represents single-stranded
      nascent molecules of messenger RNA of simian virus 40 hydrogen-bonded over a
      small portion of their length to viral DNA templates. The name "simian virus 40
      transcriptional intermediate molecules" is suggested for these naturally
      occurring DNA.RNA hybrid molecules. The DNA in the hybrid seems to be in the form
      of replicative intermediate molecules.

PMID- 4364532
TI  - Regulation of a plant 5'(3')-ribonucleotide phosphohydrolase by cyclic
      nucleotides and pyrimidine, purine, and cytokinin ribosides.
AB  - A highly specific 5'(3')-ribonucleotide phosphohydrolase has been purified
      extensively from wheat seedling leaves. While catalyzing the hydrolysis of a wide
      variety of phosphomonoesters, the enzyme has K(m) values for adenosine 5'
      monophosphate and adenosine 3'-monophosphate in the micromolar range and appears
      highly specific for 5'- and 3'-ribonucleoside monophosphates as substrates at pH
      5.0. The cyclic nucleotides adenosine 3':5'-cyclic monophosphate, guanosine 3':5'
      cyclic monophosphate, and 8-bromoadenosine 3':5'-cyclic monophosphate, as well as
      8-bromoadenosine 5'-monophosphate, are powerful competitive inhibitors of the
      enzyme; the apparent K(i) values for these nucleotides are 3.4 muM, 1.6 muM, 26
      muM, and 9.1 muM, respectively. The enzyme is inhibited noncompetitively by a
      variety of pyrimidine and purine (including cytokinin) ribosides and 2'
      deoxyribosides. Since the cyclic nucleotide competitive inhibitors are also
      active growth promoters of higher plants, and, furthermore, since elevation of
      cyclic AMP levels appears to be a consequence of some phytohormone treatments
      that promote plant growth, it is suggested that negative control of this 5'(3')
      ribonucleotide phosphohydrolase may be a significant component of growth
      regulation through the maximizing of the levels of nucleotide precursors for RNA
      and DNA synthesis.

PMID- 4364533
TI  - Rapid loss of translatable messenger RNA of phosphoenolpyruvate carboxykinase
      during glucose repression in liver.
AB  - The rate of synthesis of phosphoenolpyruvate carboxykinase (EC 4.1.1.32) in rat
      liver decreased with a half-life of 30 min after fasted rats were refed either a
      chow diet or glucose. A requirement for both glucose and insulin to bring about
      this rapid deinduction was shown, as well as the ability of dibutyryl adenosine
      3':5'-cyclic monophosphate to block the decrease in enzyme synthesis. Estimates
      of the stability of messenger RNA of phosphoenolpyruvate carboxykinase were made
      by using the inhibitors actinomycin D and cordycepin to block further messenger
      RNA synthesis, and then measuring the decrease in specific enzyme synthesis. It
      is suggested that the use of actinomycin D yields an overestimation of the
      template stability. The results with cordycepin imply that the enzyme messenger
      RNA has a short half-life of approximately 1 hr. Thus, it is possible that
      deinduction may proceed by way of a decrease in messenger RNA production, leading
      to a rapid fall in the synthesis of phosphoenolpyruvate carboxykinase.

PMID- 4364535
TI  - Synthesis and properties of Clostridium acidi-urici (Leu2)-ferredoxin: a function
      of the peptide chain and evidence against the direct role of the aromatic
      residues in electron transfer.
AB  - Tyrosyl or other aromatic residues generally occur in two conserved positions in
      the peptide chain of clostridial-type ferredoxins and have been implicated in the
      electron transfer function of these iron-sulfur proteins. We have prepared and
      determined some of the properties of a derivative of Clostridium acidi-urici
      ferredoxin, [Leu(2)]-ferredoxin, in which a leucyl residue has been substituted
      for the tyrosyl residue in position 2 from the amino terminus. [Leu(2)]
      ferredoxin is fully active as an electron carrier in two biological assays, the
      phosphoroclastic enzyme system and the ferredoxin-dependent reduction of
      cytochrome c in the presence of ferredoxin-TPN reductase and TPNH. Quantitative
      electron paramagnetic resonance experiments indicate that [Leu(2)]-ferredoxin
      accepts nearly two electrons upon enzymatic reduction by pyruvate-ferredoxin
      oxidoreductase and an excess of pyruvate. If electron transfer to an iron-sulfur
      cluster is the rate-limiting step in the assays used, and if the rate of electron
      transfer through Tyr(30) is not much faster than through Tyr(2), these results
      indicate that the primary pathway of electron transfer in clostridial-type
      ferredoxins is not via Tyr or other aromatic amino-acid residues. The syntheses
      of other ferredoxin derivatives with amino-acid substitutions or deletions in
      positions 1 and 2 indicate that a large bulky residue, but not necessarily an
      aromatic residue, is needed in position 2 for the stability of this ferredoxin.
      The residue in position 2, therefore, appears to act as a hydrophobic shield for
      an iron-sulfur cluster.

PMID- 4364534
TI  - Cholinergic augmentation of lymphocyte-mediated cytotoxicity. A study of the
      cholinergic receptor of cytotoxic T lymphocytes.
AB  - Cholinergic agonists have previously been shown to augment the ability of
      sensitized lymphocytes to injure cells bearing the sensitizing alleantigens. The
      cholinergic receptor of the attacking lymphocyte population has been studied with
      pharmacological manipulation of an in vitro system that quantitates the injury
      mediated by sensitized attacking cells upon target cells. The data reveal that
      muscarinic ligands are several orders of magnitude more potent than nicotinic
      agents in altering cytotoxicity.

PMID- 4364536
TI  - Electron transfer reactions in biological systems: the reduction of
      ferricytochrome c by chromous ions.
AB  - Chromous ion reacts with ferricytochrome c to yield a one-to-one Cr(III)
      ferrocytochrome c complex. This material, when hydrolyzed by trypsin and
      subjected to chromatographic procedures, yielded two fragments containing
      chromium. The amino-acid compositions and chemical characteristics of each of
      these fragments indicated that the chromium had crosslinked two segments of
      polypeptide chain; these were residues 40-53-Cr(III)-residues 61-72 and residues
      40-53-Cr(III)-residues 61-73. Examination of a model of the ferricytochrome c
      molecule indicated that only two residues of the crosslinked peptides were
      sufficiently close to allow crosslinking to take place. These residues were
      tyrosine 67 and asparagine 52. Enzymatic hydrolysis of one of those fragments by
      aminopeptidase M supported this identification. The position of the chromic ion
      implies what is the path of electron transfer from the chromous ion to the ferric
      ion in this chemical reduction of cytochrome c, and suggests a possible path of
      electron transfer in biological oxidation-reduction reactions.

PMID- 4364537
TI  - The three-state model: a minimal allosteric description of homotropic and
      heterotropic effects in the binding of ligands to hemoglobin.
AB  - The effect of hydrogen ion, chloride, and 2,3-diphosphoglycerate upon the oxygen
      binding of hemoglobin may be satisfactorily described by an allosteric model
      employing three affinity states. The allosteric two-state model does not provide
      even an approximate description except under defined extreme conditions. In
      particular, the two-state model cannot provide a correct interpretation of
      recently reported electron spin resonance and nuclear magnetic resonance data.

PMID- 4364538
TI  - Epstein-Barr virus-associated membrane-reactive antibodies during long term
      survival Burkitt's lymphoma.
AB  - Antibodies to Epstein-Barr virus associated cell membrane antigens persisted or
      slowly decreased during prolonged uncomplicated survival of patients with
      Burkitt's lymphoma in remission. Serum was sampled from four patients within 6
      months before recurrence occurring after the first year and preceded by remission
      during more than 6 months. Rapid and significant decreases of the antibodies
      before clinical recognition of the recurrences were found in three patients. The
      fourth patient had slowly increasing titers before relapse. Immune stimulant
      treatment during remission, with BCG (Bacille Calmette Guerin vaccine) or BCG +
      Bordetella pertussis, temporarily increased the antibody levels. Possible
      mechanisms for the observed titer changes before recurrence are discussed.

PMID- 4364539
TI  - Renal aldosterone receptors: studies with (3H)aldosterone and the anti
      mineralocorticoid (3H)spirolactone (SC-26304).
AB  - In vivo, a spirolactone (SC-26304) inhibited the effects of aldosterone on
      urinary K(+):Na(+) ratios and the binding of [(3)H]aldosterone to renal
      cytoplasmic and nuclear receptors. Cytoplasmic binding of [(3)H]aldosterone and
      [(3)H]spirolactone (SC-26304) was similar in magnitude and involved the same set
      of sites. Under three sets of conditions-(i) in the intact rat, (ii) in kidney
      slices, and (iii) in reconstitution studies (mixing prelabeled cytoplasm with
      either purified renal nuclei or chromatin), [(3)H]spirolactone (SC-26304) did not
      yield specific nuclear complexes in contrast to the reproducible generation of
      these complexes with [(3)H]aldosterone. In glycerol density gradients,
      cytoplasmic [(3)H]aldosterone receptor complexes sedimented at 8.5 S and 4 S in
      low concentrations of salt and at 4.5 S in high concentrations of salt.
      Cytoplasmic [(3)H]spirolactone (SC-26304) receptor complexes sedimented at 3 S in
      low concentrations of salt and 4 S in high concentrations of salt. These results
      are discussed in terms of an allosteric model of the receptor system.

PMID- 4364540
TI  - Cyclic 3':5'-adenosine monophosphate in Escherichia coli during transient and
      catabolite repression.
AB  - Cyclic AMP concentrations were low for an adenylate cyclase-deficient mutant
      (cya(-)) and abnormally high for a catabolite receptor protein-deficient mutant
      (crp(-)). A fall in cellular cAMP concentration was always found when cells were
      subjected to transient repression. No consistent correlations were observed
      between catabolite repression and cellular cAMP levels.

PMID- 4364541
TI  - Enhancement by carbachol of transmitter release from motor nerve terminals.
AB  - In the endplates of rat phrenic nerve-diaphragm, application of the acetylcholine
      like compound, carbachol, causes a marked increase in transmitter release, as
      measured electrophysiologically using miniature endplate potential frequency.
      Washing out of carbachol reverses the increase in frequency. The ability of
      carbachol to increase transmitter release is greatly enhanced by perfusion of the
      preparation with Ringer solution containing elevated K(+). At concentrations of
      carbachol greater than 30 muM, the onset of the postjunctional blocking action of
      carbachol is too rapid and obscures the increase in miniature potential
      frequency. The rate of increase in transmitter release is dependent on the
      concentration of carbachol applied and can be antagonized by d-tubocurarine (10
      60 nM) and other blocking compounds. These findings, in contrast to previous
      reports, indicate that cholinergic nerve endings, like adrenergic nerve endings,
      respond to applied acetylcholine-like drugs with measurable increases in
      transmitter output.

PMID- 4364543
TI  - A molecular model of high density lipoproteins.
AB  - Based on the analysis of recombined lipidapoprotein complexes by C-13 and P-31
      nuclear magnetic resonance spectroscopy and circular dichroism [Assmann, G.,
      Sokoloski, E. A. & Brewer, H. B., Jr. (1974) Proc. Nat. Acad. Sci. USA 71, 549
      553; Assmann, G., Highet, R. J., Sokoloski, E. A. & Brewer, H. B., Jr. (1974)
      Proc. Nat. Acad. Sci. USA 71, in press; Assmann, G. & Brewer, H. B., Jr. (1974)
      Proc. Nat. Acad. Sci. USA 71, 989-993] and the identification of conformational
      amphipathic regions in apoproteins, a new model for human high density
      lipoproteins is proposed. This model is analogous to membrane models proposed by
      Singer, in that protein "icebergs" are embedded in a "sea" of lipid.

PMID- 4364542
TI  - Role of phosphate and other proton-donating anions in respiration-coupled
      transport of Ca2+ by mitochondria.
AB  - Measurements of extra oxygen consumption, (45)Ca(2+) uptake, and the osmotic
      expansion of the matrix compartment show that not all permeant anions are capable
      of supporting and accompanying the energy-dependent transport of Ca(2+) from the
      medium into the matrix in respiring rat-liver mitochondria. Phosphate, arsenate,
      acetate, butyrate, beta-hydroxybutyrate, lactate, and bicarbonate + CO(2)
      supported Ca(2+) uptake, whereas the permeant anions, nitrate, thiocyanate,
      chlorate, and perchlorate, did not. The active anions share a common denominator,
      the potential ability to donate a proton to the mitochondrial matrix; the
      inactive anions lack this capacity. Phosphate and the other active permeant
      anions move into the matrix in response to the alkaline-inside electrochemical
      gradient of protons generated across the mitochondrial membrane by electron
      transport, thus forming a negative-inside anion gradient. It is postulated that
      the latter gradient is the immediate "pulling" force for the influx of Ca(2+) on
      the electrogenic Ca(2+) carrier in respiring mitochondria under intracellular
      conditions. Since mitochondria in the cell are normally exposed to an excess of
      phosphate (and the bicarbonate-CO(2) system), particularly in state 4, inward
      transport of these proton-yielding anions probably precedes and is necessary for
      inward transport of Ca(2+) and other cations under biological conditions. These
      observations indicate that a negative-inside gradient of phosphate generated by
      electron transport is a common step and provides the immediate motive power not
      only for (a) the inward transport of dicarboxylates and tricarboxylates and (b)
      the energy-dependent exchange of external ADP(3-) for internal ATP(4-) during
      oxidative phosphorylation, as has already been established, but also for (c) the
      inward transport of Ca(2+), K(+), and other cations.

PMID- 4364544
TI  - Paradoxical response to dexamethasone. A contribution to the differential
      diagnosis of adrenal hyperfunction?.

PMID- 4364545
TI  - [Preliminary note on sleep organization in blind children].

PMID- 4364546
TI  - [Apropos of a series of 134 cases of intraspinal metastases with neurologic
      complications in adults].

PMID- 4364547
TI  - [The place of the syncytial respiratory virus in current pulmonary disorders in
      children and adults].

PMID- 4364548
TI  - [Obesity as a symptom: psychodynamic classification and therapeutic management].

PMID- 4364549
TI  - [Mushroom growers' lung].

PMID- 4364550
TI  - [Acute myopericarditis and viral hepatitis].

PMID- 4364551
TI  - [Editorial: Setting daily rates and the approval of budget in public hospitals].

PMID- 4364552
TI  - Renal arteriovenous fistula secondary to metastatic tumor.

PMID- 4364553
TI  - Wilms' tumor. Treatment in an adult.

PMID- 4364554
TI  - Effect of prolonged lithium ingestion on glucagon and parathyroid hormone
      responses in rats.

PMID- 4364555
TI  - [Recent electroencephalographic data in infantile autism. Review of the
      literature].

PMID- 4364556
TI  - Endocrine laboratory assays in obstetrics and gynecology.

PMID- 4364557
TI  - [Parasitic protozoa of the blood of rodents. 3. Two new malaria parasites of
      Anomalurine flying squirrels of the Ivory Coast (author's transl)].

PMID- 4364558
TI  - Antifungal properties of polymyxin B and its potentiation of tetracycline as an
      antifungal agent.
AB  - High concentrations of polymyxin B inhibited the growth of Candida albicans and
      Saccharomyces cerevisiae. When these yeasts were incubated with concentrations of
      polymyxin B too low to affect growth, and were then exposed to tetracycline,
      protein synthesis was inhibited and at least 99% of the organisms were killed.
      Neither inhibition of protein synthesis nor cell death occurred in cultures
      treated with high concentrations of tetracycline alone. We conclude that
      polymyxin B at high concentrations affects the cell membrane of yeasts, which
      results in inhibition of growth. At low concentrations, it increases the
      permeability of the yeast cell membrane to tetracycline, which then inhibits
      protein synthesis and leads to cell death.

PMID- 4364559
TI  - Location of the T4 gene 32 protein-binding site on polyoma virus DNA.

PMID- 4364560
TI  - Interaction of N-methyl phenazinium radical cation with single-stranded
      polyriboadenylic acid.

PMID- 4364561
TI  - Localization of major group-specific polypeptides in the avian RNA tumor viruses.

PMID- 4364562
TI  - Coupling of polyoma DNA and RNA synthesis.

PMID- 4364563
TI  - Flavin binding by bacterial luciferase: affinity chromatography of bacterial
      luciferase.

PMID- 4364564
TI  - Translation of mengovirus RNA in Ehrlich ascites cell extracts.

PMID- 4364565
TI  - The effect of altered sterol composition on cytochrome oxidase and S
      adenosylmethionine: delta 24 sterol methyltransferase enzymes of yeast
      mitochondria.

PMID- 4364566
TI  - A new eukaryotic RNA polymerase factor: a factor from chicken myeloblastosis
      cells which stimulates transcription of denatured DNA.

PMID- 4364567
TI  - Isolation and terminal sequence determination of the major rat brain myelin
      proteolipid P7 apoprotein.

PMID- 4364568
TI  - Interaction of lysolecithin micelles and lecithin vesicles with apolipoprotein
      Gln I from serum high density lipoproteins.

PMID- 4364569
TI  - Effect of NH+4 and K+ on the activity of the ribosomal subunits in the EF-G- and
      EF-T-dependent GTR hydrolysis.

PMID- 4364570
TI  - [Double infections due to herpesviruses and adenoviruses in infants'
      communities].

PMID- 4364571
TI  - [New findings on the physiology and pathology of sleep from the developmental
      point of view].

PMID- 4364572
TI  - ALA synthetase induction. Inhibitory effect exerted by administration of
      dibutyryl adenosine-3',5'-cyclic monophosphate, theophylline and caffeine.

PMID- 4364573
TI  - Comparative study on induction of hepatic delta-aminolevulinate synthetase by
      different drugs.

PMID- 4364574
TI  - Are both fractions of Rhodopseudomonas spheroides Y ALA synthetase isoenzymes?

PMID- 4364575
TI  - Protohaem synthesis by the yeast Saccharomyces cerevisiae during respiratory
      adaptation. Relationships with glycogen metabolism.

PMID- 4364576
TI  - Vitamin D3 metabolites. I. Synthesis of 25-hydroxycholesterol.

PMID- 4364577
TI  - Vitamin D3 metabolites. II. Further syntheses of 25-hydroxycholesterol.

PMID- 4364578
TI  - Vitamin D3 metabolites. 3. Synthesis and X-ray analysis of 1 alpha,25
      dihydroxycholesterol.

PMID- 4364579
TI  - The cytoproct of Paramecium caudatum: structure and function, microtubules, and
      fate of food vacuole membranes.

PMID- 4364581
TI  - Cell hybridization and cancer.

PMID- 4364580
TI  - Tumour-associated hormonal products.

PMID- 4364582
TI  - Molecular pathology of the cancer cell.

PMID- 4364583
TI  - Effects of tumour viruses on cell growth.

PMID- 4364584
TI  - Hormones and neoplasia.

PMID- 4364585
TI  - [A case of ectopic gonadotropin producing cholangioma (author's transl)].

PMID- 4364586
TI  - Characteristics of Sendai virus receptors in a model membrane.

PMID- 4364587
TI  - Replication of polyoma DNA in isolated nuclei. 3. The nucleotide sequence at the
      RNA-DNA junction of nascent strands.

PMID- 4364588
TI  - Letter: Evidence for non-repetitive subunits in the genome of Rous sarcoma virus.

PMID- 4364589
TI  - Logical analysis of the mechanism of protein folding II. The nucleation process.

PMID- 4364590
TI  - A re-examination of the renal blastema graft model for Wilms tumor production.

PMID- 4364591
TI  - [Insulinoma].

PMID- 4364592
TI  - [Multiplication of Mycobacterium lepraemurium in cell-free liquid medium. I.
      Establishment of the NC medium (author's transl)].

PMID- 4364593
TI  - [Multiplication of Mycobacterium lepraemurium in cell-free liquid medium. II. The
      growth curve of M. lepraemurium in the NC medium and the pathogenicity of the
      bacilli grown in the medium (author's transl)].

PMID- 4364594
TI  - Editorial: Vaccine against cytomegalovirus.

PMID- 4364595
TI  - [Arterial hypertension as a risk factor in the development of arteriosclerosis].

PMID- 4364596
TI  - [Nuclease activity in the cultural fluid filtrate of actinomycetes--producers of
      antibiotics].

PMID- 4364597
TI  - [The antirachitic activity of lumisterol-3].

PMID- 4364598
TI  - Spread of an avian adenovirus (CELO virus) to uninoculated fowls.

PMID- 4364599
TI  - The survival of foot-and-mouth disease virus in African buffalo with non
      transference of infection to domestic cattle.

PMID- 4364600
TI  - [Benign tumors of the esophagus (7 cases)].

PMID- 4364601
TI  - [Functioning tumor of the pancreas (insulinoma)].

PMID- 4364602
TI  - [Report of resection of a malignant esophagostenosis (author's transl)].

PMID- 4364603
TI  - Influence of human ceruloplasmin on the aggregation of human platelets by
      adenosine diphosphate.

PMID- 4364604
TI  - Errata: Demonstration of platelet fibrinogen secretion via the surface connecting
      system.

PMID- 4364605
TI  - Studies on the pathogenesis of iodide myxedema.

PMID- 4364606
TI  - The mechanism of activation of hormone-sensitive lipase.

PMID- 4364607
TI  - Action of cholera toxin to stimulate adenyl cyclase.

PMID- 4364608
TI  - Extracellular deoxyribonuclease production by anaerobic bacteria.
AB  - The production of extracellular deoxyribonuclease was examined with anaerobic
      organisms isolated from clinical specimens. Nuclease activity was extraordinarily
      common. All strains of Fusobacterium, including eight species, as well as
      Bacteroides fragilis and B. melaninogenicus, displayed enzyme activity. Whereas
      the gram-positive bacteria were generally less productive, all strains of
      Clostridium perfringens, Peptostreptococcus intermedius, and P. anaerobius
      specifically produced deoxyribonuclease. The test is taxonomically valuable,
      particularly in the characterization of gram-positive cocci, since a
      deoxyribonuclease-producing coccus indicates P. intermedius or P. anaerobius.
      Additionally, possession of the enzyme may prove to be a useful correlate of the
      potential pathogenicity of anaerobes.

PMID- 4364609
TI  - Method for isolation and selection of temperature-sensitive mutants of herpes
      simplex virus.
AB  - A method for induction and selection of temperature-sensitive mutants of herpes
      simplex virus is presented. After the infected cells were treated with 5
      bromodeoxyuridine, the virus was extracted by repeated freezing and thawing and
      cloned in microcultures which were then incubated at permissive temperature until
      viral plaques appeared. The microcultures were then replicated at nonpermissive
      temperature. Clones not forming plaques in these latter were further purified and
      examined for temperature-sensitive characteristics. Viral clones mutated in
      plaque-forming ability or in yield were obtained and preliminarily characterized.

PMID- 4364610
TI  - Effect of culture medium and carbon dioxide concentration on growth of anaerobic
      bacteria commonly encountered in clinical specimens.
AB  - Representative strains of anaerobic bacteria from human infections were used to
      evaluate broth media, gas mixtures, and inocula for use in developing a procedure
      for performing minimal inhibitory concentration antimicrobic susceptibility
      tests. Nine commercially available media, including two that were chemically
      defined, were tested. Tests were performed in atmospheres with carbon dioxide
      concentrations between 2.5 and 10% and also in the GasPak system (BBL) that had a
      disposable hydrogen-carbon dioxide generator. Growth curves on each organism
      grown in schaedler broth and a 5% carbon dioxide atmosphere were used to
      determine growth characteristics, equate time of the particular growth phases to
      turbidity readings, and determine the numbers of viable organisms present in the
      culture. Schaedler broth proved to be most advantageous in combination with an
      atmosphere of 5% carbon dioxide, 10% hydrogen, and 85% nitrogen. The growth curve
      studies yielded valuable data on the rapidity and quantity of growth under these
      conditions. We believe these data have provided information which can be used as
      the basis for developing a standardized procedure for antimicrobic susceptibility
      testing for anaerobic bacteria.

PMID- 4364611
TI  - Apparatus for conditioning unlimited quantities of finished waters for enteric
      virus detection.
AB  - An apparatus has been developed, constructed, and tested for conditioning
      unlimited quantities of finished waters for enteric virus detection.

PMID- 4364612
TI  - Metabolic adaptations in skeletal muscle of streptozotocin-diabetic rats
      following exercise training.

PMID- 4364613
TI  - Incorporation of 131-I-labeled androgen-receptor into nuclei of rat prostates.

PMID- 4364614
TI  - The influence of cyclic GMP on polypeptide synthesis in a cell-free system
      derived from wheat embryos.

PMID- 4364616
TI  - The conformation of oxytocin in dimethylsulfoxide as revealed by carbon-13 spin
      lattice relaxation times.

PMID- 4364615
TI  - An apolipoprotein preferentially enriched in cholesteryl ester-rich very low
      density lipoproteins.

PMID- 4364617
TI  - Conversion of diglyceride to triglyceride by rat liver microsomes: a requirement
      for the 105,000 x g supernatant.

PMID- 4364618
TI  - Cobalt cytochrome C: preparation of characterization.

PMID- 4364619
TI  - Action of Solanum malacoxylon on calcium metabolism in the rat.

PMID- 4364620
TI  - Selective chemical modification of arginine residues in mitochondrial malate
      dehydrogenase.

PMID- 4364621
TI  - Role of lecithin in D-beta-hydroxybutyrate dehydrogenase function.

PMID- 4364623
TI  - In vivo regulation of hepatic protein kinase by adenosine 3',5'-monophosphate
      mediated glucagon stimulation.

PMID- 4364622
TI  - Soluble & membrane-bound superoxide dismutases in a blue-green algae
      (Spirulina)and spinach.

PMID- 4364624
TI  - Synthesis of glucosylceramide by purified calf spleen beta-glucosidase.

PMID- 4364625
TI  - Discharge patterns of cat raphe neurons during sleep and waking.

PMID- 4364626
TI  - Developmental variations of choline acetyl-transferase, dopamine-beta-hydroxylase
      and monoamineoxidase in chicken embryo and chicken sympathetic ganglia.

PMID- 4364627
TI  - Connectivity changes of Ia afferents on axotomized motoneurons.

PMID- 4364628
TI  - Streptomycin resistance and ribosomal proteins: amino acid substitutions in the
      str protein of one streptomycin-resistant mutant of Escherichia coli K12 after
      mutagenesis with ethyl methanesulfonate.

PMID- 4364629
TI  - Two cAMP-activated protein kinases from bovine thyroid.

PMID- 4364630
TI  - The synthesis of diastereomeric epoxy-(beta-D-glucopyranosyl)ethanes and 1,2
      epoxy-3-(beta-D-glucopyranosyl)propanes, as irreversible inhibitors of beta-D
      glucosidase.

PMID- 4364631
TI  - Identification of iduronic acid as a constituent of the "type-specific"
      polysaccharide of Clostridium perfringens Hobbs 10.

PMID- 4364632
TI  - The ultrastructure of the accessory sex organs of the male rat. VI. The effect of
      cyproterone acetate on the dorsal lobe and the coagulating gland.

PMID- 4364633
TI  - The development and fine structure of the ultimobranchial glands in larval Rana
      temporaria L.

PMID- 4364634
TI  - Developmental genetics of teleosts: a biochemical analysis of lake chubsucker
      ontogeny.

PMID- 4364635
TI  - The content of pyridine dinucleotides in the mouse embryo before implantation.

PMID- 4364636
TI  - Effect of phenobarbital administration on the subcellular distribution of vitamin
      D3-3H in rat liver.

PMID- 4364637
TI  - Effects of calcitonin in the concentration of cyclic adenosine 3',5'
      monophosphate in rat kidney in vivo and in vitro.

PMID- 4364638
TI  - Purified somatotrophs from rat adenohypophysis: response to secretagogues.

PMID- 4364639
TI  - Embryonic chick intestine in organ culture: interaction of adenylate cyclase
      system and vitamin D3-mediated calcium absorptive mechanism.

PMID- 4364640
TI  - Thyrotropin-releasing hormone stimulation and somatostatin inhibition of growth
      hormone secretion from perfused rat adenohypophyses.

PMID- 4364641
TI  - Observations on the effects of chromate on the thyroid.

PMID- 4364642
TI  - Secretion of ACTH by isolated anterior pituitary cells: kinetics of stimulation
      of corticotropin-releasing factor and of inhibition by corticosterone.

PMID- 4364643
TI  - Mineralocorticoid receptors in salt-susceptible and salt-resistant rats.

PMID- 4364644
TI  - Lead aggravates viral disease and represses the antiviral activity of interferon
      inducers.
AB  - Lead acetate was administered continuously in the drinking water to CD-1 male
      mice beginning at 4 weeks of age. An LD(10-20) of the lytic viruses or 300 plaque
      forming units of RLV was inoculated intrapertioneally at 6 weeks of age. Lead
      increased the response of the mice to all classes of viruses against which it was
      tested: an RNA picornavirus-encephalomyocarditis (EMCV), a DNA herpesvirus
      pseudoribies, an RNA leukemia-virus-Rauscher leukemia (RLV), an RNA arbovirus B
      St. Louis encephalitis, and an RNA arbovirus A-western encephalitis. Most studies
      were performed between lead and EMCV. Increases in EMCV mortality in lead treated
      mice over controls ranged from 2x at a lead level of 0.004M to 7x (100%
      mortality) at a 0.1M lead level. Splenomegaly with spleens 800 to 1100 mg in
      weight containing high titers of RLV occurred in lead (0.03M)-treated mice 3 and
      6 weeks after RLV inoculation; spleens or RLV controls were normal in weight (200
      mg) and were free of virus. Lead did not reduce the protective effect of mouse
      interferon (IF) against the lethal action of EMCV, but it did repress the EMCV
      antiviral effect of poly I/poly C (PIC) and of Newcastle disease virus (NDV)
      against EMCV mortality. These data indicate several new facts concerning adverse
      effects lead may have on an animal: (1) lead aggravates viral disease, most
      likely in part, through reduced IF synthesis; (2) lead represses the anti-EMCV
      protective effects of both PIC and of NDV, which, in other reports, were shown to
      induce IF in radioresistant macrophages (PIC) or in radiosensitive lymphocytes
      (NDV); (3) lead may then be said to repress IF induction in two kinds of cells;
      (4) however, lead does not inhibit IF action.

PMID- 4364645
TI  - Lead-induced inclusion bodies: composition and probable role in lead metabolism.
AB  - Lead-induced inclusion bodies in renal tubular cells of rats have been studied in
      vitro after isolation by differential centrifugation. The inclusion bodies are
      insoluble in physiological media but may be dissolved in denaturants like 6M urea
      and sodium deoxycholate. They contain about 40-50 mug of lead/mg protein, but
      only about 10% of this is tightly bound. They also contain calcium, iron, zinc,
      copper, and cadmium. The protein is rich in glutamic and aspartic acids, glycine
      and cystine. When dissolved in 6M urea, the protein migrates as a single band on
      acrylamide gel electrophoresis and has a molecular weight of 27,500. It is
      suggested that the inclusion bodies function as an intracellular depot of
      nondiffusible lead. Further studies have been directed toward finding a free,
      unaggregated lead-containing protein fraction. Nuclear proteins from kidneys of
      lead-toxic rats were separated into NaCl-, Tris-, and NaOH-soluble fractions and
      an insoluble acidic fraction. A quantitatively small lead-containing protein was
      found in the 0.14M NaCl fraction. Amino acid composition, electrophoretic
      mobility, molecular weight, and ability to bind lead are similar to those of
      insoluble inclusion body protein. The possible role of this soluble lead-binding
      protein in the formation of nuclear inclusion bodies is at present time not
      certain. These studies do suggest, however, that protein-bound lead in renal
      tubular cells may be partitioned between insoluble and nondiffusible
      morphologically discrete inclusion bodies and a soluble, extractable fraction
      which is presumably diffusable.

PMID- 4364647
TI  - Demonstration of a reaggregation inhibitor in sea urchin embryos.

PMID- 4364646
TI  - Red cell lead, whole blood lead, and red cell enzymes.
AB  - Simultaneous assay of blood lead (Pb-B) and red cell lead (Pb-Rbc) in 123 samples
      from 104 urban and suburban students, ages 10-18, shows the ratio of
      concentration (Pb-Rbc)/(Pb-B) to increase as the hematocrit decreases. On direct
      assay in 40 samples, plasma lead (Pb-P) was fixed in a narrow range. In 28
      students with Pb-Rbc >40 mug/100 ml, the mean red cell 2,3-diphosphoglycerate
      (2,3-DPG) was 6.05+/-0.28 (+/-S.E.), significantly higher (P<.025) than the
      5.25+/-0.18 of 51 students with Pb-Rbc<40 mug/100 ml, although hemoglobin values
      were comparable (13.83+/-0.31 versus 13.55+/-0.20). Analysis of the individual
      population groups showed this correlation of Pb-Rbc with 2,3-DPG to be primarily
      related to the intercorrelation of each parameter with hemoglobin.Rbc membrane
      Na/K ATPase, as per cent of total membrane ATPase, had a median value of 60% in
      48 subjects. Na/K ATPase below 60% was found in 10 (77%) of the 13 students with
      Pb-Rbc>/=40 mug/100 ml, but in only 14 of the 35 with Pb-Rbc<40 mug/100 ml
      (chi(2)=5.1, df=1, P<0.05). Correlation of significant enzyme changes with Pb
      Rbc, but not with Pb-B in the normal urban range of Pb-B<35 mug/100 ml suggests
      Pb-Rbc, increased in anemia, to be a critical factor in the hematotoxicity of
      lead.

PMID- 4364648
TI  - Retraction fibers and leucocyte chemotaxis.

PMID- 4364649
TI  - Effect of proteolytic inhibitors on growth and surface architecture of normal and
      transformed cells.

PMID- 4364650
TI  - Uncoupler-stimulated adenosine triphosphatase activity. Deficiency in intact
      mitochondria from Morris hepatomas and ascites tumor cells.

PMID- 4364651
TI  - Sugar transport in chick embryo fibroblasts. II. Alterations in transport
      following transformation by a temperature-sensitive mutant of the Rous sarcoma
      virus.

PMID- 4364652
TI  - The isolation and partial characterization of two novel sphingolipids from
      Neurospora crassa: di(inositolphosphoryl)ceramide and ((gal)3glu)ceramide.

PMID- 4364653
TI  - Inositol phosphorylceramide, a novel substance and the chief member of a major
      group of yeast sphingolipids containing a single inositol phosphate.

PMID- 4364654
TI  - Nucleoside diphosphokinase of Salmonella typhimurium.

PMID- 4364655
TI  - Inhibition of macromolecular synthesis in Escherichia coli by protease
      inhibitors. Specific reversal by glutathione of the effects of chloromethyl
      ketones.

PMID- 4364656
TI  - Thermodynamic parameters for the hydrolysis of inorganic pyrophosphate at pH 7.4
      as a function of (Mg2+), (K+), and ionic strength determined from equilibrium
      studies of the reaction.

PMID- 4364657
TI  - Regulation of protein synthesis during density-dependent growth inhibition of
      BHK21-13 cells.

PMID- 4364658
TI  - Isolation and relationship of human hexosaminidases.

PMID- 4364659
TI  - The equilibria and reaction rates of nicotinamide-adenine dinucleotide and its
      related compounds with cyanide ion in the presence of polyelectrolytes.

PMID- 4364660
TI  - Differential effects of adenylyl imidodiphosphate on adenosine triphosphate
      synthesis and the partial reactions of oxidative phosphorylation.

PMID- 4364661
TI  - Studies with cyclic adenosine monophosphate receptor and stimulation of in vitro
      transcription of the Gal operon.

PMID- 4364662
TI  - Stimulation and desensitization of macrophage adenylate cyclase by prostaglandins
      and catecholamines.

PMID- 4364663
TI  - The enhancement of macrophage adenylate cyclase by products of activated
      lymphocytes.

PMID- 4364665
TI  - Formation of a novel nucleotide by fat cell preparations containing adenylate
      cyclase.

PMID- 4364664
TI  - Casein kinase from the Golgi apparatus of lactating mammary gland.

PMID- 4364666
TI  - A histochemical characterization of malignant tumour mucins as a possible aid in
      the identification of metastatic deposits.

PMID- 4364667
TI  - The determination of low density lipoproteins by micro-nephelometry: a practical
      assessment.

PMID- 4364668
TI  - [Nucleic acids, high-molecular polyphosphates and some polyphosphate metabolic
      enzymes in a synchronized culture of Schizosaccharomyces pombe yeasts].

PMID- 4364669
TI  - [Characteristics of yeast mitochondria from Endomyces magnusii isolated by a
      fermentation method].

PMID- 4364670
TI  - Cystosarcoma phylloides in a twelve-year-old girl.

PMID- 4364671
TI  - [The evaluation of arterial hypertension (author's transl)].

PMID- 4364672
TI  - Studies on growth homone secretion. VI. Effects of dibutyryl cyclic AMP,
      prostaglandin E1, and indomethacin on growth and hormone secretion by rat
      pituitary tumor cells in culture.

PMID- 4364673
TI  - Cyclic AMP regulation of prostaglandin biosynthesis in fat cells.

PMID- 4364674
TI  - [Fetoproteins of human cancer].

PMID- 4364675
TI  - [Pre-beta lipoprotein in the plasma of normal adults].

PMID- 4364676
TI  - [Study of experimental chronic bronchitis in the rat].

PMID- 4364677
TI  - [Changes of hippocampal single-cell activity in emotion and motivation-active
      stimuli].

PMID- 4364678
TI  - The effect of L-tryptophane upon the elaboration and extinction of a conditioned
      avoidance response and upon the behaviour of rats.

PMID- 4364680
TI  - Binding of calcium to a cell membrane-enriched preparation from pig myocardium:
      increase in calcium affinity upon membrane protein phosphorylation enhanced by a
      membrane-bound cyclic AMP-dependent protein kinase.

PMID- 4364679
TI  - Cyclic AMP-dependent protein kinase activity in a cell membrane-enriched
      subcellular fraction of pig myocardium.

PMID- 4364681
TI  - Subcellular localisation and properties of contractile protein ATPases of blood
      platelets.

PMID- 4364682
TI  - Cyclic AMP and platelet aggregation.

PMID- 4364683
TI  - Platelet aggregation in the rat--relation to human thrombopathias.

PMID- 4364684
TI  - The release reaction.

PMID- 4364685
TI  - Enzymes of purine metabolism in platelets: phosphoribosylpyrophosphate synthetase
      and purine phosphoribosyltransferases.

PMID- 4364686
TI  - Hypoxanthine-guanine phosphoribosyltransferase deficiency: altered kinetic
      properties of a specific mutant form of the enzyme.

PMID- 4364687
TI  - Mutant phosphoribosylpyrophosphate synthetase in two gouty siblings with
      excessive purine production.

PMID- 4364688
TI  - Increased PP-ribose-P synthetase activity: a genetic abnormality leading to
      excessive purine production and gout.

PMID- 4364689
TI  - An unusual case of glycogen storage disease.

PMID- 4364690
TI  - Human glltamine phosphoribosylpyrophosphate (PP-ribose-P) amidotransferase:
      kinetic, regulation and configurational changes.

PMID- 4364691
TI  - Xanthine oxidase and aldehyde oxidase in purine and purine analogue metabolism.

PMID- 4364692
TI  - Human phosphoribosylpyrophosphate (PP-ribose-P) synthetase: properties and
      regulation.

PMID- 4364693
TI  - Regulatory aspects of the synthesis of 5-phosphoribosyl-1-pyrophosphate in human
      red blood cells.

PMID- 4364694
TI  - Hormonal control of skeletal and mineral homeostasis.

PMID- 4364695
TI  - Familial association of metabolic myopathy, lactic acidosis and sideroblastic
      anemia.

PMID- 4364696
TI  - Fat metabolism in higher plants. Recent studies on plant alpha-oxidation systems.

PMID- 4364697
TI  - Catalytic properties of three lactate dehydrogenases from potato tubers (Solanum
      tuberosum).

PMID- 4364698
TI  - Regulatory sulfhydryl groups, conformational change, and allosteric inhibition in
      rabbit muscle fructose diphosphatase.

PMID- 4364699
TI  - Effects of visual pigments on the organization of phospholipid multibilayer model
      membranes--a spin probe study.

PMID- 4364700
TI  - [Spontaneous nephroblastomas in SPF Han rats].

PMID- 4364701
TI  - [Mechanism of action of iodo-4-salicylic acid on the respiration of isolated
      mitochondria].

PMID- 4364703
TI  - The effect of sulisoxazole (Gantrisin) and albumin on bilirubin conjugation in
      cultures of a clonal cell line with liver-like functions.

PMID- 4364702
TI  - The mode of action of metronidazole in Trichomonas vaginalis and other micro
      organisms.

PMID- 4364704
TI  - Antibodies to the unfolded form of a helix-rich region in staphylococcal
      nuclease.

PMID- 4364705
TI  - Changes in apolipoproteins and properties of rabbit very low density lipoproteins
      on induction of cholesteremia.

PMID- 4364706
TI  - Two pictures of a lipid bilayer. A comparison between deuterium label and spin
      label experiments.

PMID- 4364707
TI  - Enzymatic synthesis of deoxyribonucleic acids with repeating sequences. A new
      repeating trinucleotide deoxyribonucleic acid, d(T-C-C)n-d(G-G-A)n.

PMID- 4364708
TI  - Tritium-hydrogen exchange of the cyclic peptide polymyxin B-1.

PMID- 4364709
TI  - Magnetic resonance studies of the geometry of bound nicotinamide adenine
      dinucleotide and isobutyramide on spin-labeled alcohol dehydrogenase.

PMID- 4364710
TI  - Specificity of chemical modification of ribonucleic acid transport by liver
      carcinogens in the rat.

PMID- 4364711
TI  - Binding of lanthanides and of divalent metal ions to porcine trypsin.

PMID- 4364712
TI  - [Effect of a new derivative of cyclic AMP on the liberation and synthesis of
      growth hormone and pituitary prolactin].

PMID- 4364713
TI  - [Characterization of a hybrid cell line, "human leukemia-Chinese hamster"].

PMID- 4364714
TI  - Protective effect of interferon on mice experimentally infected with Japanese
      encephalitis virus.

PMID- 4364715
TI  - [Prostaglandins: biological action and therapeutic prospects].

PMID- 4364716
TI  - Improving psychiatric drug therapy. A matter of dosage and choice.

PMID- 4364717
TI  - Inhibition of hepatoma-immune lymph-node cell cytotoxicity by tumour-bearer
      serum, and solubilized hepatoma antigen.

PMID- 4364718
TI  - Inheritance of susceptibility to Friend mouse leukemia virus. X. Separate genetic
      control of two viruses in Friend virus preparation.

PMID- 4364719
TI  - Specific neutralizing antibodies in Epstein-Barr virus associated diseases.

PMID- 4364720
TI  - Influence of age and 3-methylcholanthrene on azo-dye carcinogenesis and
      metabolism of p-dimethylaminoazobenzene in rat liver.

PMID- 4364721
TI  - Increase in viral antigen in individual polyoma-virus-infected mouse kidney cells
      as studied by quantiative immunofluorescence.

PMID- 4364722
TI  - The effects of long-term feeding of DDT to BALB-c mice.

PMID- 4364723
TI  - A rapid destructive effect of the Schmidt-Ruppin strain of Rous sarcoma virus on
      transformed rat cell lines.

PMID- 4364724
TI  - Genetic control of MuLV-gs expression in crosses between high and low leukemia
      incidence strains.

PMID- 4364725
TI  - Cherubism.

PMID- 4364726
TI  - Extraction and analysis of carotenoids in fresh plant materials.

PMID- 4364727
TI  - Rapid screening method for analysis of chlorinated pesticide and polychlorinated
      biphenyl residues in fish.

PMID- 4364728
TI  - Rapid screening method for examining corn and corn-derived products for possible
      aflatoxin contamination.

PMID- 4364729
TI  - Failure to detect, in human sera, antibodies cross-reactive with group-specific
      antigens of murine leukemia virus.

PMID- 4364730
TI  - Chemodectomas in dogs: epidemiologic comparisons with man.

PMID- 4364731
TI  - A rapid dialysis cell in the zirconyl gel assay for carcinoembryonic antigen in
      human serum.

PMID- 4364732
TI  - Prevalence of endogenous type-C virus in normal hamster tissues and hamster
      tumors induced by chemical carcinogens, simian virus 40, and polyoma virus.

PMID- 4364733
TI  - Responses of isolator-derived and conventional chickens to Marek's disease
      herpesvirus and avian leukosis virus.

PMID- 4364734
TI  - Effect of aminoacetonitrile on the metabolism of diethylnitrosamine during liver
      carcinogenesis.

PMID- 4364735
TI  - Transmission of the mammary tumor virus by the GR mouse strain. II. Genetic
      studies.

PMID- 4364736
TI  - Immunotherapy of cancer: regression of established intradermal tumors after
      intralesional injection of mycobacterial cell walls attached to oil droplets.

PMID- 4364737
TI  - Potential carcinogens. I. Carcinogenicity of some plant extracts and their tannin
      containing fractions in rats.

PMID- 4364738
TI  - BALB-cfR3: a new high mammary-tumor and high leukemia mouse strain.

PMID- 4364739
TI  - Protection against guinea pig hepatomas by pretreatment with subcelluar fractions
      of Mycobacterium bovis (BCG).

PMID- 4364740
TI  - Hepatocarcinogenic material in urine specimens from humans consuming aflatoxin.

PMID- 4364742
TI  - [Recent advances in the study of metabolism of collagen].

PMID- 4364741
TI  - A one cell-cycle delay for tumor cytostasis in vitro: effects of dibutyryl cyclic
      AMP or embryonic extracts on synchronized cultures of a murine tumor.

PMID- 4364743
TI  - [Symposium I: The skin and cyclic AMP].

PMID- 4364744
TI  - Effect of soluble and membrane proteins upon diethyl ether extraction of aqueous
      phospholipid dispersions.

PMID- 4364745
TI  - Bis-(monoacylglyceryl)phosphate and acyl phosphatidylglycerol isolated from human
      livers of lipidosis induced by 4,4'-diethylaminoethoxyhexesterol.

PMID- 4364746
TI  - Phospholipids of two strains of dermatophyte, Arthroderma uncinatum.

PMID- 4364747
TI  - [Steroid therapy using ACTH or corticoids? Indications, effectiveness, and
      adverse effects of ACTH-therapy].

PMID- 4364748
TI  - Biological characters of Staphylococcus aureus isolated from diseased chickens.

PMID- 4364749
TI  - Axonal filamentous spheroids associated with cardiomyopathy with "targetoid
      fibers". I. Clinical, histologic, and electron microscopic studies.

PMID- 4364750
TI  - [Sorption capacity of colloidal silicic acid for polyethylene glycol and
      polyethylene glycol derivatives. Report I. Quantitative course and sorption
      mechanisms in water suspensions].

PMID- 4364751
TI  - Malignant tumors of the trachea. A new outlook.

PMID- 4364752
TI  - Diabetes and Addison's disease.

PMID- 4364753
TI  - [Clinical expereience with Iruxol in miscellaneous surgical patients (author's
      transl)].

PMID- 4364754
TI  - Flunitrazepam (Ro 5-4200) and sleep cycle in insomniac patients.

PMID- 4364755
TI  - Cytochemical observations on the midpiece of the spermatozoa of the gastropod
      Biomphalaria glabrata.

PMID- 4364756
TI  - [Endolymphatic radiotherapy in cancer of the cervix (author's transl)].

PMID- 4364757
TI  - [Hepatic cholangiohamartomas (von Meyenburg complexes) (author's transl)].

PMID- 4364758
TI  - A case of Raynaud's syndrome of peculiar origin.

PMID- 4364759
TI  - Is the inhibition of glutamic-pyruvic transaminase by phenylalanine one of the
      causes of hypoglucosemia in phenylketonurics?

PMID- 4364760
TI  - Latest developments in the treatment of amebiasis.

PMID- 4364761
TI  - Adrenocortical responses of the Apollo 17 crew members.

PMID- 4364762
TI  - In vitro antiviral activity and preliminary clinical trials of a new adamantane
      compound.
AB  - A compound, 1'-methyl spiro (adamantane-2,3'-pyrrolidine) maleate, chemically
      related to the antiviral drug amantadine, was tested for activity in vitro
      against a number of human respiratory viruses. By a variety of techniques, it was
      shown to be active against a wide range of human and animal influenza A viruses.
      The effect was, however, variable and ranged from high activity against two 1957
      Asian strains to no observable activity against a 1971 strain. Like amantadine,
      the drug did not inhibit the growth of influenza B viruses. It was also inactive
      against a number of paramyxoviruses. Unlike amantadine, the drug did inhibit
      rhinoviruses, but to a lesser extent than myxoviruses. The coronavirus 229E was
      also sensitive to the action of the drug in vitro. Although an earlier trial in
      volunteers showed that, when given orally from 2 days before until 5 days after
      virus challenge, the drug was protective against infection with influenza A/Hong
      Kong/68 virus, a similar trial in volunteers challenged with rhinoviruses 2 and 9
      revealed no useful activity against rhinoviruses in man.

PMID- 4364764
TI  - Regulation of the diurnal rhythm of rat liver beta-hydroxy-beta-methylglutaryl
      coenzmye A reductase activity by insulin, glucagon, cyclic AMP and
      hydrocortisone.

PMID- 4364763
TI  - Antiviral activity of cytarabine in herpesvirus-infected rats.
AB  - Intranasal inoculation of herpesvirus (approximately 1.8 mean lethal doses
      [LD(50)] in 0.1 ml) into 105- to 115-g rats produces paralytic disease in 4 to 5
      days and 80 to 100% mortality in 8 to 12 days. Cytarabine (ara-C) (40 to 320
      mg/kg), administered subcutaneously to inoculated rats, delays the onset of
      paralysis and protects the animals from death. Drug treatments were given twice
      daily for 5 days. Beneficial drug effects were observed even when initiation of
      therapy was delayed for 3 days after virus inoculation. A dose-response
      relationship existed when therapy was initiated at 4 h after virus inoculation.
      However, when therapy was delayed for 3 days, it appeared that the highest drug
      level (320 mg/kg twice daily) was somewhat less effective than the lower doses
      (160 and 80 mg/kg twice daily). Virus could be detected in homogenates of brain
      beginning 3 days after inoculation, and the titer increased through 7 days. Ara-C
      treatment, initiated 4 h after inoculation, caused a delay in the appearance of
      virus, and a reduction in the titer in the brain homogenates. No virus was
      detected in blood serum, or in homogenates prepared from lung, kidney, thymus, or
      spleen of infected rats. The virus titration studies are in agreement with the
      illness and mortality produced by herpesvirus infection.

PMID- 4364765
TI  - Thermodynamic relationships between the oxidation-reduction reactions and the ATP
      synthesis in suspensions of isolated pigeon heart mitochondria.

PMID- 4364766
TI  - Formation of the yeast mitochondrial membrane. 3. Accumulation of mitochondrial
      proteins synthesized in both the cytoplasm and mitochondria in yeast undergoing
      glucose depression.

PMID- 4364767
TI  - The use of 13C spin lattice relaxation times to study the interaction of alpha
      methyl-D-glucopyranoside with concanavalin A.

PMID- 4364768
TI  - Factors affecting the formation of phytol and its incorporation into chlorophyll
      by homogenates of the leaves of the french bean Phaseolus vulgaris.

PMID- 4364769
TI  - Heme-heme interaction in cytochrome c oxidase: the cooperativity of the hemes of
      cytochrome c oxidase as evidenced in the reaction with CO.

PMID- 4364770
TI  - Stimulation of the incorporation of 32Pi and myo-(2-3H)inositol into the
      phosphoinositides in polymorphonuclear leukocytes during phagocytosis.

PMID- 4364771
TI  - Inhibition of nucleic acid synthesis in Ehrlich tumor cells by periodate-oxidized
      adenosine and adenylic acid.

PMID- 4364772
TI  - Ferrochelatase activity in wild-type and mutant strains of Spirillum itersonii.
      Solubilization with chaotropic reagents.

PMID- 4364773
TI  - Alterations of the aryl hydrocarbon hydroxylase system during riboflavin
      depletion and repletion.

PMID- 4364774
TI  - New cyclopentenyl fatty acids in Flacourtiaceae. Straight-chain fatty acids and
      cyclic fatty acids in lipids during maturation of the seeds.

PMID- 4364775
TI  - Adenosine diphosphate as a regulatory ligand in beef heart cytosol nucleoside
      diphosphokinase.

PMID- 4364777
TI  - Effect of magnesium adenosine 5'-triphosphate on the accessibility of the iron of
      clostridial azoferredoxin, a component of nitrogenase.

PMID- 4364776
TI  - Molecular characterization of proteins in detergent solutions.

PMID- 4364778
TI  - A convenient micro method for the quantitation of closed circular
      deoxyribonucleic acid.

PMID- 4364780
TI  - Conformation of angiotensin II in aqueous solution. Titration of several peptide
      analogs and homologs.

PMID- 4364779
TI  - Partial characterization of the sexual agglutination factor from Hansenula wingei
      Y-2340 type 5 cells.

PMID- 4364781
TI  - Bone turnover-sex hormone-parathyroid hormone interrelationships in
      postmenopausal osteoporosis.

PMID- 4364782
TI  - The temporal order of replication of some DNA cistrons.

PMID- 4364783
TI  - The mechanism of SV40 DNA replication.

PMID- 4364785
TI  - Cleavage of mouse DNA by a restriction enzyme as a clue to the arrangement of
      genes.

PMID- 4364784
TI  - Replication of mitochondrial DNA: replicative forms of molecules from rat tissues
      and evidence for discontinuous replication.

PMID- 4364786
TI  - Genetic organization and regulation of the Drosophila Y chromosome.

PMID- 4364787
TI  - Recent DNA fiber diffraction studies and their implications for DNA recognition.

PMID- 4364788
TI  - Some properties of RNA:protein complexes from the nucleus of eukaryotic cells.

PMID- 4364789
TI  - [Complement fixation reaction for Mycoplasma pneumoniae in the serologic
      diagnosis of respiratory diseases].

PMID- 4364790
TI  - A comparison of DNA binding proteins from normal and virus-transformed mouse
      cells.

PMID- 4364791
TI  - Intracerebral transplantation of human rhabdomyosarcoma cells into fetal and
      newborn kittens.

PMID- 4364792
TI  - Mammary tumor virus (MTV) antigens in normal and mammary tumor-bearing mice.

PMID- 4364793
TI  - Differences in cytochalasin B inhibition of 3-O-methylglucose uptake between BALB
      3T3 cells and a murine sarcoma virus transformed clone.

PMID- 4364794
TI  - A study of herpes simplex type 2 antibody status in groups of patients with
      cervical neoplasia in Czechoslovakia.

PMID- 4364795
TI  - The humoral antibody response to a primary viral neoplasm (MSV) through its
      entire course in BALB-c mice.

PMID- 4364796
TI  - Influence of interferon on virus particle formation in different oncornavirus
      carrier cell lines.

PMID- 4364797
TI  - Serum effects on cell-mediated destruction of Rous sarcomas.

PMID- 4364798
TI  - Antibody to Epstein-Barr virus in man in Australia and New Guinea.

PMID- 4364799
TI  - The histogenesis of tumours induced in golden hamsters by murine sarcoma virus
      Harvey (MSV-H).

PMID- 4364800
TI  - Carcinogenicity of nitrosamines and methanesulphonate esters given
      intraperitoneally, in RF mice.

PMID- 4364801
TI  - Cyclic-AMP in ocular tissues of the rabbit, monkey, and human.

PMID- 4364802
TI  - Carbon-13 nuclear relaxation measurements in nicotinamide adenine dinucleotide
      and adenosine monophosphate.

PMID- 4364803
TI  - Kinetic studies of the reduction of ferricytochrome c by Fe(EDTA)2-.

PMID- 4364804
TI  - Effects of a prolonged 3-hour sleep-wake cycle on sleep stages, plasma cortisol,
      growth hormone and body temperature in man.

PMID- 4364805
TI  - A rapid assay for 25-OH-vitamin D3 without preparative chromatography.

PMID- 4364806
TI  - Oxytocin receptors in human uterus.

PMID- 4364807
TI  - A study of thyrotropin deficiencies by the combination of two tests of TSH
      function.

PMID- 4364808
TI  - Recovery of hypothalamic-pituitary-adrenal function, growth hormone
      responsiveness and sleep EEG pattern in a patient following removal of an adrenal
      cortical adenoma.

PMID- 4364809
TI  - Hypothalamic-pituitary function in the olfacto-genital syndrome.

PMID- 4364811
TI  - Glandular end organ deficiency associated with secretion of biologically inactive
      pituitary peptides.

PMID- 4364810
TI  - Multiple hormones in a bronchial tumor.

PMID- 4364812
TI  - Prostaglandin E (PGE) control of cell proliferation in vitro: characteristics of
      HT-29.

PMID- 4364813
TI  - Editorial: The value of scanning in hepatic cirrhosis.

PMID- 4364814
TI  - [Chromatography of the para-influenza viruses on certain ion exchangers].

PMID- 4364815
TI  - The agent of trachoma. Recent studies of the biology, biochemistry and immunology
      of a prokaryotic obligate parasite of eukaryocytes.

PMID- 4364816
TI  - Localisation of a fibroblast growth factor and its effect alone and with
      hydrocortisone on 3T3 cell growth.

PMID- 4364817
TI  - In vitro and in vivo phosphorylation of myelin basic protein by cerebral protein
      kinase.

PMID- 4364818
TI  - Induced redistribution of membrane particles, anionic sites and con A receptors
      in Entamoeba histolytica.

PMID- 4364819
TI  - Urinary excretion of carnitine in progressive muscular dystrophy.

PMID- 4364820
TI  - Biologic exposure to dental materials.

PMID- 4364821
TI  - Production of O2- in photolyzed water demonstrated through the use of superoxide
      dismutase.

PMID- 4364822
TI  - Protein binding of 3',5'-adenosine cyclic monophosphate acid.

PMID- 4364823
TI  - Heterogeneity of the inner mitochondrial membrane through the unequal
      distribution of phospholipid unsaturation.

PMID- 4364824
TI  - Association of cowpea mosaic virus-induced double-stranded RNA with a
      cytopathological structure in infected cells.

PMID- 4364825
TI  - A nonselective analysis of SV40 transformation of mouse 3T3 cells.

PMID- 4364826
TI  - Inhibition of influenza and parainfluenza virus replication in tissue culture by
      2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA).

PMID- 4364827
TI  - Isolation of defective viruses from SV40-transformed human and hamster cells.

PMID- 4364828
TI  - Characteristics of murine C-type viruses. II. The behavior of viruses resident in
      various cell lines and their hybrids on BALB-3T3 and mouse embryo fibroblast
      cultures.

PMID- 4364829
TI  - Maturation of vesicular stomatitis virus: electron microscopy of surface replicas
      of infected cells.

PMID- 4364830
TI  - The involvement of NADH-cytochrome b5 reductase and cytochrome b5 complex in
      microsomal NADH-cytochrome c reductase activity. Resolution of the complex by
      triton X-100.

PMID- 4364831
TI  - The involvement of NADH-cytochrome b5 reductase and cytochrome b5 complex in
      microsomal NADH-cytochrome c reductase activity. Changes in NADH-cytochrome c
      reductase activity following phenobarbital treatment.

PMID- 4364832
TI  - Labyrinthine morphology and temperature in cryosurgery (guinea pig).

PMID- 4364833
TI  - Isoleucyl transfer ribonucleic acid synthetase from Escherichia coli. Effect of
      limited cleavage by trypsin on activity and structure.

PMID- 4364834
TI  - Fluorescence energy transfer between the thiamine diphosphate and flavine adenine
      dinucleotide binding sites on the pyruvate dehydrogenase multienzyme complex.

PMID- 4364835
TI  - Fluorescent affinity labeling of initiation site on ribonucleic acid polymerase
      of Escherichia coli.

PMID- 4364837
TI  - Conformational transitions of cyclic adenosine monophosphate receptor protein of
      Escherichia coli. A temperature-jump study.

PMID- 4364836
TI  - Conformational transitions of cyclic adenosine monophosphate receptor protein of
      Escherichia coli. A fluorescent probe study.

PMID- 4364839
TI  - A new method of assay for polynucleotide ligase.

PMID- 4364838
TI  - Interaction of apolipoprotein-alamine and apolipoprotein-glutamine-I with
      phosphatidylcholine. Effect on solute quenching of intrinsic fluorescence.

PMID- 4364840
TI  - Chemical synthesis of ppGpp.

PMID- 4364841
TI  - Serum lipoprotein apoproteins as major protein constituents of the human
      erythrocyte membrane.

PMID- 4364842
TI  - Effect of neuraminidase on the synthesis of collagen and other proteins.

PMID- 4364843
TI  - Magnetic studies on the changes in the iron environment in Chromatium
      ferricytochrome c'.

PMID- 4364844
TI  - A method for the preparation of desialylated human chorionic gonadotropin and its
      sub-units.

PMID- 4364845
TI  - [Wart-like epidermodysplasia of Lewandowsky-Lutz observed in a subject from
      Cameroon].

PMID- 4364846
TI  - Aberrant carotid artery simulating a tumor of the middle ear.

PMID- 4364847
TI  - Effects of antibiotics on intracellular symbiotes in the pea aphid, Acyrthosiphon
      pisum.

PMID- 4364848
TI  - Fine structure of frog lime sacs.

PMID- 4364849
TI  - A comparative ultrastructural study of the pars tuberalis of various mammals, the
      chicken and the newt.

PMID- 4364850
TI  - The cell-types in the adenohypophysis of the Indian catfish Heteropneustes
      fossilis (Bloch).

PMID- 4364851
TI  - Intraependymal cerebrospinal fluid contacting neurons and axon terminals on the
      external surface in the filum terminale of the carp (Cyprinus carpio).

PMID- 4364852
TI  - The fine structure of the digital pads of rhacophorid tree frogs.

PMID- 4364853
TI  - Comparative studies on porcine and human high density lipoproteins.

PMID- 4364854
TI  - Characterization and quantification of a crustacean lipovitellin.

PMID- 4364855
TI  - Some enzymic reactions of adenine derivatives in the tail muscle of the lobster,
      Homarus americanus.

PMID- 4364856
TI  - Fish liver fructose 1,6-diphosphatase. II. "Neutral" and "alkaline" forms.

PMID- 4364857
TI  - The amino acid sequence of ostrich (Struthio camelus) cytochrome c.

PMID- 4364858
TI  - DNCB reactivity in patients with skin carcinoma.

PMID- 4364859
TI  - [Potential generation on bilayer lipid membranes, containing Fe3+ and ubiquinone,
      during oxidation-reduction reactions at the separation boundary].

PMID- 4364860
TI  - Modulation of mitochondrial adenylate kinase by citric-acid-cycle intermediates.

PMID- 4364861
TI  - The effect of lanthanide ions on the conformation of adenine mononucleotides and
      dinucleotides.

PMID- 4364862
TI  - Characterization of the single-strand-specific nuclease S1 activity on double
      stranded supercoiled polyoma DNA.

PMID- 4364863
TI  - Structural studies on phenylalanine transfer ribonucleic acid from yeast with the
      spectroscopic label formycin.

PMID- 4364864
TI  - Intracellular cyclic AMP level and intestinal smooth muscle relaxation.

PMID- 4364865
TI  - Interactions between peripheral and hypothalamic carbachol stimulation of
      drinking in the rat.

PMID- 4364866
TI  - Chromosomal and nonchromosomal mutations affecting the "killer character" of
      Saccharomyces cerevisiae.
AB  - The "killer character" of Saccharomyces cerevisiae is a nonchromosomal genetic
      element which imparts to cells carrying it (a) the ability to kill cells which
      lack it, by secreting the soluble macromolecular killer substance and (b) the
      ability to resist the killing effects of the killer substance.-Mutants have been
      isolated from S. cerevisiae carrying the "killer character". Mutants were found
      in two nuclear genes (mak1 and mak2) involved in maintenance of the genetic
      element of the killer character. Mutants in three other nuclear genes could
      maintain the cytoplasmic genetic element normally; two of these were able to
      express resistance to killing, but not the ability to kill (kex1 and kex2), while
      the third could express the killing function, but was sensitive to killing and is
      thus a "suicide" strain (rex1). These five nuclear genes were all distinct.
      Several mutants were detected which showed non-mendelian segregation indicating
      mutation of the "cytoplasmic" genetic element. Some such mutants had normal
      resistance to killing but were either unable to kill at all or showed marked
      reduction in the ability to kill. Others had lost both killing ability and
      resistance. None were suppressive.-Two nonkilling mutants, both of which showed
      cytoplasmic inheritance, were mated. A large, but variable, proportion of diploid
      colonies, plated after several generations of growth, showed normal killing which
      has then stably inherited on further subcloning.

PMID- 4364868
TI  - Proceedings: The effect of cyclic AMP and cyclic GMP on the histology of the
      neonatal rat hepatocytes.

PMID- 4364867
TI  - Phosphatases within the cartilage of the mandibular condyle of the mouse.

PMID- 4364870
TI  - Proceedings: Adrenergic and cholinergic innervation of arteriovenous anastomoses:
      the effect of 6-hydroxydopamine.

PMID- 4364869
TI  - Proceedings: Evidence that large granular vesicles are not involved in
      transmitter release from adrenergic nerves.

PMID- 4364871
TI  - Proceedings: Interrelationship between swimming performance and chronological
      age, dental age, skeletal age of age group competitive swimmers.

PMID- 4364872
TI  - The rapid isolation of plant virus RNAs using sodium perchlorate.

PMID- 4364874
TI  - Studies in genetic resistance to RSV (RAV-O). A third type of genetic resistance
      typified by the W line of fowl and further support for the two loci genetic
      model.

PMID- 4364873
TI  - Human serum lipoproteins as inhibitors of haemagglutination for selected
      togaviruses.

PMID- 4364875
TI  - On the nature of poliovirus genetic recombinants.

PMID- 4364876
TI  - Retarded growth of poliovirus in contact inhibited cells.

PMID- 4364877
TI  - A temperature-sensitive mutant of vesicular stomatitis virus with two abnormal
      virus proteins.

PMID- 4364878
TI  - Bovine enterovirus-1: characterization, replication and cytopathogenic effects.

PMID- 4364879
TI  - Murine sarcoma virus-induced cytopathological effects in mouse cells made
      resistant to 6-azauridine.

PMID- 4364880
TI  - The effect of an antireceptor serum on mammalian cell lines.

PMID- 4364881
TI  - A locus affecting circulating interferon levels induced by mouse mammary tumour
      virus.

PMID- 4364882
TI  - Association of foot-and-mouth disease virus replicase with RNA template and
      cytoplasmic membranes.

PMID- 4364883
TI  - A stable syncytial mutant of herpes simplex type 2 virus.

PMID- 4364884
TI  - [Ultrastructural changes of neurons and synapses in the neocortex, striatum, and
      thalamus induced by oxygen deficiency in the guinea pig (Cavia porcellus L.)].

PMID- 4364885
TI  - Heparin anticoagulation as adjuvant to chemotherapy in carcinoma of the lung.

PMID- 4364886
TI  - Effects of sodium warfarin and other carcinostatic agents on malignant cells: a
      study of drug synergy.

PMID- 4364887
TI  - Potential of yttrium-aluminum-garnet laser in caries prevention.

PMID- 4364888
TI  - [Radiological study of the internal auditory canal].

PMID- 4364889
TI  - [Technetium 99m labeled sodium pyrophosphate for the study of malignant bone
      tumors].

PMID- 4364890
TI  - [A new method for the isotopic diagnosis of primary hepatomas using
      selenomethionine].

PMID- 4364891
TI  - [Pigmented villo-nodular synovitis of the hip with bone manifestations].

PMID- 4364892
TI  - [False cyst of the pancreas with intrahepatic development].

PMID- 4364893
TI  - [Cystic tumors of the nephrogenous cord].

PMID- 4364894
TI  - Ribonucleotides linked to DNA of herpes simplex virus type 1.
AB  - Cells of a continuous cell line derived from rabbit embryo fibroblasts were
      infected with herpes simplex type 1 virus (HSV-1) and maintained in the presence
      of either [5-(3)H]uridine or [methyl-(3)H]thymidine or (32)PO(4) (3-).
      Nucleocapsids were isolated from the cytoplasmic fraction, partially purified,
      and treated with DNase and RNase. From the pelleted nucleocapsids, DNA was
      extracted and purified by centrifugation in sucrose and cesium sulfate gradients.
      The acid-precipitable radioactivity of [5-(3)H]uridine-labeled DNA was partially
      susceptible to pancreatic RNase and alkaline treatment; the susceptibility to the
      enzyme decreased with increasing salt concentration. No drop of activity of DNA
      labeled with [(3)H]thymidine was observed either after RNase or alkali treatment.
      Base composition analysis of [5-(3)H]uridine-labeled DNA showed that the
      radioactivity was recovered as uracil and cytosine. In the cesium sulfate
      gradient, the purified [5-(3)H]uridine-labeled DNA banded at the same position as
      the (32)P-labeled DNA. The present data tend to suggest that ribonucleotide
      sequences are present in HSV DNA, that they are covalently attached to the viral
      DNA, and that they can form double-stranded structures.

PMID- 4364895
TI  - Inhibition of the multiplication of vesicular stomatitis and Newcastle disease
      virus by 2-deoxy-d-glucose.
AB  - The production of infectious vesicular stomatitis (VSV) and Newcastle disease
      virus can be completely inhibited by 2-deoxy-d-glucose in pyruvate-containing
      medium, if virus either grown in pyruvate-containing medium or dialyzed against
      phosphate-buffered saline is used for infection. Under these conditions, the
      synthesis of all VSV proteins is reduced. VSV RNA, which is synthesized at
      reduced rates, seems to be unstable. The effect is completely reversible. If
      virus grown in glucose-containing medium is used for infection, the production of
      both viruses is not significantly inhibited by 2-deoxy-d-glucose. Under these
      conditions the production of the VSV glycoprotein is specifically impaired, but
      does not lead to a marked reduction of the yield of infectious virus.

PMID- 4364896
TI  - Immunochemical characterization of two major polypeptides from murine mammary
      tumor virus.
AB  - A major murine mammary tumor viral (MMTV) antigen, sl, originally described by
      Nowinski et al. (1967, 1968, 1971), has been purified from RIII mouse milk MMTV
      by sequential ion-exchange and gel chromatography. The purified protein with sl
      antigenic reactivity contains carbohydrate, and has an apparent minimal molecular
      weight of 52,000. It can be designated as gp52 (sl). Another major MMTV viral
      protein with a molecular weight of 27,000 has also been isolated, and antisera
      have been prepared against it. Both MMTV gp52 (sl) and p27 viral polypeptides
      have been iodinated with (125)I and used in immunoprecipitation and competition
      assays. The two MMTV proteins differ absolutely from each other and from major
      mouse type C viral polypeptides in molecular weight, immunological reactivity,
      and amino acid composition. Purified gp52 (sl) in radioimmunoprecipitation
      inhibition assays reacted in two distinct patterns. One pattern showed partial
      displacement of antibody which could be converted to the second, a complete
      displacement, by heating the antigen, presumably by exposing additional reactive
      determinants. Biologically, the patterns of major MMTV polypeptide expression in
      milk correlated with spontaneous mammary tumor incidence in different strains of
      mice, indicating that the sl antigen is group specific for MMTV or that several
      mouse strains contain the same virus type.

PMID- 4364897
TI  - Harvey sarcoma virus: a second murine type C sarcoma virus with rat genetic
      information.
AB  - The nucleic acid sequences found in the Harvey strain of murine sarcoma virus
      have been analyzed by RNA.[(3)H]DNA and [(3)H]RNA.DNA hybridization techniques.
      The Harvey strain of murine sarcoma virus has been found to possess at least two
      sets of nucleic acid sequences. One set of sequences is contained in the Moloney
      strain of mouse type-C virus, and the other set is contained in DNA transcripts
      synthesized in endogenous reactions containing rat type-C virus(es). The nucleic
      acid sequences that are detected in the Harvey sarcoma virus with the DNA probes
      synthesized from the rat type-C virus(es) are related to the rat sequences
      detected in the Kirsten strain of murine sarcoma virus. The results support the
      model that both Kirsten and Harvey sarcoma viruses arose through a process of
      recombination or reassortment between mouse type-C viruses and sequences in rat
      cells and suggest that the information for transformation of fibroblasts may be
      contained in the rat type-C or cellular genome.

PMID- 4364898
TI  - Conditional lethal mutants of adenovirus 2-simian virus 40 hybrids. I. Host range
      mutants of Ad2+ND1.
AB  - Human adenovirus type 2 (Ad2) grows poorly in monkey cells, although this defect
      can be overcome by co-infection with simian virus 40 (SV40). The nondefective Ad2
      SV40 hybrid virus, Ad2(+)ND1, replicates efficiently in both human and African
      green monkey kidney cells, presumably due to the insertion of SV40 sequences into
      the Ad2 DNA. Several mutants of Ad2(+)ND1 have been isolated that grow and plaque
      poorly in monkey cells, although they retain the ability to replicate and plaque
      efficiently in HeLa cells. One of these mutants (H39) has been examined in
      detail. Studies comparing the DNA of the mutant with Ad2(+)ND1 either by the
      cleavage patterns produced by Escherichia coli R.RI restriction endonuclease
      digestion or by heteroduplexing reveal no differences. The pattern of protein
      synthesis of Ad2(+)ND1 and H39 in monkey cells is quite different with the mutant
      resembling Ad2, which is defective in the synthesis of late proteins. However, in
      human cells, the proteins synthesized by H39 and the parent Ad2(+)ND1 are very
      similar. The production of SV40 U antigen in H39-infected cells is different from
      that in Ad2(+)ND1-infected cells. Finally, the growth of H39 in monkey cells can
      be complemented by SV40.

PMID- 4364899
TI  - Virion-bound protein kinase in Semliki forest and Sindbis viruses.
AB  - Semliki forest virus and Sindbis virus (Alphaviruses belonging to the togavirus
      group) grown in BHK-21 cells possessed very low levels of virion-associated
      protein kinase activity. For comparison, vesicular stomatitis virus, also grown
      in BHK-21 cells, contained a virion-bound protein kinase which had a specific
      activity 80 times greater than that of the Alphaviruses. The Alphavirus protein
      kinase was unmasked by the nonionic detergent Nonidet P-40 but was not activated
      by cyclic nucleotides. Phosvitin was the best exogenous phosphate acceptor for
      assaying the viral enzyme in vitro. Phosphoprotein phosphatase activity was also
      detected in the Alphaviruses. Both in vivo and in vitro, all of the viral
      structural polypeptides were phosphorylated, and the phosphorylated amino acids
      were found to be serine and threonine. The viral nucleocapsid protein was about
      four times more efficient as a phosphate acceptor than were the envelope
      proteins. From 33 to 50% of the total protein kinase was bound to the viral
      nucleocapsid, and the specific activity of this enzyme was 4 to 10 times greater
      than that associated with the viral envelope.

PMID- 4364900
TI  - Simian virus 40 transcription in productively infected and transformed cells.
AB  - Several independent cell lines transformed by simian virus 40 carry a species of
      viral RNA of 900,000 to 1,000,000 daltons. A viral RNA species of similar size is
      found early in the lytic cycle. Late in the viral lytic cycle, two prominent
      viral RNA species of about 600,000 and 900,000 daltons are seen. The larger late
      species shares nucleotide sequences with, and is less stable than, the smaller.
      These RNA species are located in the cytoplasm of the infected cell. The regions
      of the viral genome coding for these RNA species are mapped by hybridization of
      lytic RNA species to fragments of the genome produced by cleavage with
      Haemophilus aegyptius endonuclease.

PMID- 4364901
TI  - Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses.
      Transformation of hamster kidney cells by adenovirus 2 and the nondefective
      hybrid viruses.
AB  - Nonhybrid adenovirus 2 (Ad2) and five nondefective Ad2-simian virus 40 (SV40)
      hybrids (Ad2(+)ND(1)-Ad2(+)ND(5)) failed to produce tumors when injected into
      newborn hamsters. However, each of these agents transformed hamster kidney cells
      in vitro, and the transformed cell lines produced tumors when injected into
      suckling hamsters. Foci of cells transformed by the hybrids could not be
      distinguished from foci of cells transformed by nonhybrid Ad2.
      Histopathologically, tumors induced by the nondefective hybrid-transformed lines
      were of the adenovirus type with no areas of SV40-type fibrosarcoma. All of the
      cell lines studied contained Ad2 T antigen and Ad2 RNA. Only the B55HK(1) line
      contained the three early SV40 antigens, U, TSTA, and T. The ND(4)HK(1) line
      contained SV40 T and TSTA antigens (the latter antigen being detected only after
      48 to 49 tissue culture passages) and SV40 RNA. The ND(2)HK(2) line contained
      SV40 RNA but no detectable SV40 antigens; the other hybrid-transformed lines
      contained no SV40 RNA. The transformation of hamster cells by the nondefective
      Ad2-SV40 hybrids seemed to be caused by the Ad2 genome and could not be
      attributed to the regions of the SV40 genome contained within the hybrids.
      Additionally, these results indicate that interactions between the genomes of the
      nondefective hybrid viruses and the hamster cells they transform are complex and
      could involve the site of integration, the size of the incorporated viral genome,
      the transcription or translation of the viral genome, or various combinations of
      these processes.

PMID- 4364902
TI  - Virion-associated RNA primer for Rous sarcoma virus DNA synthesis: isolation from
      uninfected cells.
AB  - Uninfected chicken, duck, rat, and human fibroblast cells in culture contained a
      tRNA-like RNA molecule which was structurally identical to a virion-associated
      RNA primer for in vitro Rous sarcoma virus DNA synthesis. This primer RNA
      appeared to be a normal tRNA of these cells. It was not found in a number of
      lower eukaryotic cells or in Escherichia coli.

PMID- 4364903
TI  - Inactivation of herpes simplex virus by concanavalin A.
AB  - The infectivity of herpes simplex virus type 1 (HSV-1) was inactivated after
      treatment with either concanavalin A (ConA) or periodate. Phytohemagglutinin,
      wheat germ agglutinin, pokeweed mitogen, and neuraminidase failed to inactivate
      the virus. The effect of ConA could be specifically inhibited or reversed by the
      addition of alpha-methyl-d-glucoside or alpha-methyl-d-mannoside. Evidence was
      obtained that HSV-1 inactivated by ConA could adsorb to host cells. Viral
      aggregation was not a major mechanism in the inactivation of HSV-1 by ConA. Under
      the experimental conditions employed, inactivation of HSV-1 was faster by ConA
      than by antiserum and less temperature dependent. A ConA-resistant fraction was
      detected which appeared to adsorb less quickly than untreated virus, and
      penetration of ConA-resistant fraction was strikingly slow. The presence of
      aggregates in the virus preparation did not appear to account for the ConA
      resistant fraction. Inactivation of viral infectivity by ConA was obtained only
      with enveloped viruses, since HSV-1, HSV-2, pseudorabies, and vesicular
      stomatitis virus were inactivated and vaccinia and echovirus type 6 were not.

PMID- 4364904
TI  - Endogenous C-type virus of a mouse cell line and its defectiveness.
AB  - MLg cells originating from a newborn ddY mouse began to release C-type virus by
      treatment with 5-iodo-2'-deoxyuridine (5 mug/ml) for 48 h, or spontaneoulsy after
      prolonged cultivation. The data indicated the presence of three categories of the
      viruses spontaneously induced, i.e., virus equipped with the abilities of
      infecting and transforming the S+L- C182 cells, virus which can infect C182 cells
      but is unable to transform C182 cells, and virus which cannot infect nor
      transform the C182 cells, but is positive for the XC test. The type of the virus
      produced depended upon the cell clone. With the advance in the passage level, the
      cell population was dominated by the cells producing, uniquely, the last category
      of the virus.

PMID- 4364905
TI  - Cellular replication and the persistence of inducible RNA type C viruses.
AB  - Cells of mouse and rat origin contain endogenous type C viruses. There are
      intrinsic regulatory factors which restrict the ability of different classes of
      these inducible viruses to persist in cells after chemical activation. The
      cellular block to certain viruses is shown to be overcome under conditions in
      which the virus-activated cells are allowed continued exponential growth. These
      findings may help to explain the high frequency at which replicating type C
      viruses are detectable in naturally occurring tumors of some species.

PMID- 4364906
TI  - [Human lipid metabolism in conditions of sealed chambers].

PMID- 4364907
TI  - Ocular myopathy. A case history with electron microscopy, biochemistry and review
      of literature.

PMID- 4364908
TI  - [Gamma-orbitography with 203Hg-neohydrin and 67Ga-citrate].

PMID- 4364909
TI  - Effect of cyclic AMP and some structural analogues on the dark repair inhibition
      by caffeine of uv-irradiated cells.

PMID- 4364910
TI  - [Action of arginine in a recurrent hepatic coma complicating a feminizing tumor
      of the adrenal cortex with hepatic metastases].

PMID- 4364911
TI  - [Incidence of psycho-emotional manifestations in the triggering of episodes of
      ventricular tachycardia].

PMID- 4364912
TI  - [A cause of error in the laboratory determination of masculine fertility].

PMID- 4364913
TI  - [Acute lupus erythematosus induced by procainamide].

PMID- 4364914
TI  - [Simultaneous presence of Mycobacterium tuberculosis and Mycobacterium bovis in
      pathologic human fluids. Biological problems].

PMID- 4364915
TI  - [Preclinical health examinations using automated data processing. Current state.
      Perspectives of the future].

PMID- 4364916
TI  - [Juvenile diabetes and primary optic atrophy].

PMID- 4364917
TI  - [Chronic cor pulmonale due to schistosomiasis].

PMID- 4364918
TI  - [Primary nevocarcinoma of the esophagus].

PMID- 4364919
TI  - [A case of hyperthyroidism with adrenal insufficiency and hemolytic anemia.
      Positive action of corticotherapy].

PMID- 4364920
TI  - [One year prostatic carcinoma-registry (author's transl)].

PMID- 4364921
TI  - [Vitellogenesis in Bothriocephalus clavibothrium Ariola, 1899 (Cestoda:
      Pseudophyllidea) (author's transl)].

PMID- 4364922
TI  - Effects of vestibular nuclei lesions on vestibulo-ocular reflexes and posture in
      monkeys.

PMID- 4364923
TI  - Spindle responses in pig eye muscles.

PMID- 4364924
TI  - The mechanism of interaction of red cell organic phosphates with hemoglobin.

PMID- 4364925
TI  - Focal nodular hyperplasia of the liver. Possible relationship to oral
      contraceptives.

PMID- 4364926
TI  - Ten thousand consecutive frozen sections. A retrospective study focusing on
      accuracy and quality control.

PMID- 4364927
TI  - Letter: Ferruginous bodies in lung tissue.

PMID- 4364928
TI  - Colitis cystica profunda.

PMID- 4364929
TI  - Congenital band of the abdomen and the amniotic etiology of bands.

PMID- 4364930
TI  - Serum lipids and lipoproteins in hepatosis of pregnancy and pre-eclampsia.

PMID- 4364931
TI  - Rapid ACTH test with plasma aldosterone levels. Improved diagnostic
      discrimination.

PMID- 4364932
TI  - Diagnostic use of glucagon-induced insulin response. Studies in patients with
      insulinoma or other hypoglycemic conditions.

PMID- 4364933
TI  - Goltz syndrome with multiple giant-cell tumor-like lesions in bones. A case
      report.

PMID- 4364934
TI  - Vincristine neurotoxicity.

PMID- 4364935
TI  - Letter: "Swiss-cheese" platelets.

PMID- 4364936
TI  - Letter: Gastrin and islet-cell tumors.

PMID- 4364937
TI  - Susceptibility of herpesviruses to cytosine arabinoside: standardization of
      susceptibility test procedure and relative resistance of herpes simplex type 2
      strains.
AB  - Susceptibility testing of herpes simplex type 1 (HSV-1) and type 2 (HSV-2)
      viruses to cytosine arabinoside (Ara-C) has been standardized under conditions of
      optimal reproducibility, susceptibility, and simplicity. Standard conditions were
      defined as virus inoculum of 10(1.5) to 10(2.5) TCID(50), WI-38 strain of lung
      fibroblasts, 2-day incubation, and observation of virus cytopathic effect after
      staining by the May-Greenwald-Giemsa method. The variability of minimum
      inhibitory concentration (MIC) of cytopathic effect was fourfold within each test
      and sixfold in successive assays. MIC values of all seven tested HSV-1 strains
      were in the range of 0.25 to 0.75 mug per ml, whereas four of nine HSV-2 strains
      had MIC values of 0.9 mug per ml and greater. A similar method can be used for
      assay of virus inhibitory titers of body fluids.

PMID- 4364938
TI  - Lividomycin resistance in staphylococci by enzymatic phosphorylation.
AB  - Enzymatic inactivation of lividomycin (LV) was attempted with nine clinical
      isolates of staphylococci including LV-susceptible and -resistant strains. LV
      inactivation and the incorporation into LV of (32)P from gamma-(32)P-adenosine
      triphosphate were demonstrated in the presence of cell-free extracts from LV
      resistant strains but not from LV-susceptible ones. The enzyme was purified
      approximately 82-fold from a resistant Staphylococcus aureus strain by means of
      ammonium sulfate fractionation and column chromatography. Some properties of the
      partially purified LV-phosphorylating enzyme were quite similar to those of an
      enzyme from Escherichia coli carrying an R factor conferring LV resistance, and
      the phosphorylated product of the drug was also found to be identical with that
      produced by E. coli carrying an R factor, i.e., 5''-phosphoryl-LV.

PMID- 4364939
TI  - Analysis of 2-acetylaminofluorene: residues in laboratory chow and
      microbiological media.

PMID- 4364941
TI  - The variable course of primary hepatocellular carcinoma.

PMID- 4364940
TI  - A monomolecular electron transfer chain: structure and function of cytochrome C3.

PMID- 4364942
TI  - Sleep and delirium after open heart surgery.

PMID- 4364943
TI  - Growth pattern and dietary intake of children with chronic renal insufficiency.
AB  - The growth pattern and dietary intake of 33 children with varying degrees of
      renal insufficiency has been investigated. The development of impaired renal
      function in infancy has a more deleterious effect on linear growth than has its
      onset in later years. A reduction in growth velocity may occur once the
      glomerular filtration rate falls below 25 ml/min/1.73m(2). There was a
      significant reduction of the energy, protein, and vitamin D intakes of children
      with renal insufficiency compared with those recommended for their age, and of
      energy intake compared with that of normal children of their own height. Reduced
      growth velocity occurred when energy intake fell below 80% of that recommended.
      The reduction in the intake of energy and nutrients in these children may in part
      be responsible for their growth retardation.

PMID- 4364944
TI  - Viability and pathogenicity of entomogenous fungi after prolonged storage on
      silica gel at -20degrees C.

PMID- 4364945
TI  - Corynebacterium okanaganae, an entomopathogenic species of the
      Corynebacteriaceae.

PMID- 4364947
TI  - [Phosphorylation of histone F-1 in thymocytes].

PMID- 4364946
TI  - [Comparative study of the action of collagenase and L-acetidinic 2-carboxylic
      acid on dental morphogenesis in vitro].

PMID- 4364948
TI  - Primary tumours of salivary glands: analysis of 111 tumours.

PMID- 4364950
TI  - [Opacification laryngography: technic, results and indications].

PMID- 4364949
TI  - Conformational flexibility of the neurohypophyseal hormones oxytocin and lysine
      vasopressin. A carbon-13 spin-lattice relaxation study of backbone and side
      chains.

PMID- 4364951
TI  - Role of cyclic adenosine 3',5'-monophosphate in lymphocyte mitogenesis.

PMID- 4364953
TI  - Spin-label studies of a hapten-combining site of rainbow trout antibody.

PMID- 4364952
TI  - Alteration of rabbit PCA reaction by drugs known to influence intracellular
      cyclic AMP.

PMID- 4364954
TI  - Properties of antisera to ganglioside GM1 and asialo GM1.

PMID- 4364955
TI  - Increase in Gross (G) antigen sites on the surface of AKR virus-induced rat
      lymphoma cells after treatment with trypsin.

PMID- 4364956
TI  - The variability of plasma oestradiol concentration in late pregnancy.

PMID- 4364957
TI  - Adrenal response in pregnancy to long-acting tetracosactrin.

PMID- 4364958
TI  - An evaluation of cytology in the diagnosis of herpes simplex virus infection and
      cytomegalovirus infection of the cervix uteri.

PMID- 4364959
TI  - [Chronic rheumatoid arthritis].

PMID- 4364960
TI  - [Autopsy case of diffuse scleroderma with silicosis].

PMID- 4364961
TI  - [Clinical application of an angiotension II analogue].

PMID- 4364962
TI  - Synovial sarcoma of the cervical area.

PMID- 4364963
TI  - [Cytochromes and the respiratory intensity of the bacteroids from lupine
      tubercles inoculated with effective and ineffective strains of Rhizobium lupini].

PMID- 4364964
TI  - [Determination of iron-porphyrin enzymes using a small, highly sensitive
      chemiluminescence apparatus].

PMID- 4364965
TI  - [Purification and properties of the extracellular alkaline phosphodiesterase of
      Penicillium chrysogenum 152A].

PMID- 4364966
TI  - Differential labeling of triglycerides and polar lipids of cultured mammalian
      cells by albumin-bound (1-14C) fatty acids of serum.

PMID- 4364967
TI  - The cytidine mechanism and methylation pathway in the formation of N-methylated
      ethanolamine phosphoglycerides in Neurospora crassa.

PMID- 4364968
TI  - Letter: On the repression of mitochondrial DNA transcription by fructose 1.6
      diphosphate and its derepression by cyclic adenosine 3',5'-monophosphate.

PMID- 4364969
TI  - Wilms's tumor in three children of a woman with congenital hemihypertrophy.

PMID- 4364970
TI  - [Effects of corticosteroids on experimental epileptogenic foci].

PMID- 4364971
TI  - Jaw metastases.

PMID- 4364972
TI  - Multiple denticle formation.

PMID- 4364974
TI  - [Corticocerebellar unit activity and ocular movements: saccadic-related changes
      during sleep and waking (author's transl)].

PMID- 4364973
TI  - A preview of growth hormone stimulation tests in children.

PMID- 4364975
TI  - Limitations of angiography and scanning in diagnosis of liver masses.

PMID- 4364976
TI  - Tumor detection and localization with 99mTc-tetracycline.

PMID- 4364977
TI  - [Editorial: Futile substrate cyclization and malignant hyperthermia].

PMID- 4364978
TI  - Studies on the mechanism of fructose-induced hyperuricemia in man.

PMID- 4364979
TI  - Observations of altered intracellular phosphoribosylpyrophosphate (PP-ribose-P)
      in human disease.

PMID- 4364980
TI  - Human erythrocyte phosphoribosylpyrophosphate content and "generation" during a
      constant rate infusion of xylitol.

PMID- 4364981
TI  - Electrophoretic separation of normal and mutant phosphoribosylpyrophosphate
      synthetase.

PMID- 4364982
TI  - Diagnostic value of Bekesy comfortable loudness tracings.

PMID- 4364983
TI  - Glomus tympanicum tumor in infancy.

PMID- 4364984
TI  - Malignant fibrous histiocytoma of the maxilla. A report of an unusual lesion.

PMID- 4364985
TI  - Chemical, biochemical and toxicological differences between carbon tetrachloride
      and chloroform. A critical review of recent investigations of these compounds in
      mammals.

PMID- 4364986
TI  - ATP balance and the effect of 2,4-dinitrophenol on fatty acid synthesis.

PMID- 4364987
TI  - The sphingolipid composition of human renal carcinoma.

PMID- 4364988
TI  - The lipid composition of the salt (rectal) gland of spiny dogfish.

PMID- 4364989
TI  - Isolation and characterization of an unsaponifiable lipid from Neurospora crassa.

PMID- 4364990
TI  - The nuclear lipids of bovine hypertrophic thyroid.

PMID- 4364991
TI  - Interaction of I-anilino-8-naphthalene sulphonate with human serum low-density
      lipoprotein.

PMID- 4364992
TI  - Stimulation by angiotensin of myocardial prostaglandin synthesis.

PMID- 4364993
TI  - The rate of polypeptide chain elongation in a cell-free system from Krebs II
      ascites cells.

PMID- 4364994
TI  - Modification of cytidine residues with a bisulfite-O-methylhydroxylamine mixture.

PMID- 4364995
TI  - Aetiology and prevention of wound infection in appendicetomy.

PMID- 4364996
TI  - Proceedings: active enhancement of mouse skin allografts: the effect of
      Bordetella pertussis and regional lymphadenectomy.

PMID- 4364997
TI  - Proceedings: The effects of mercury perchloride solution on collagen synthesis in
      rat colon anastomoses.

PMID- 4364998
TI  - Proceedings: Comparison of 99Tc-labelled polyphosphate, pyrophosphate and ethane
      hydroxydiphosphonate in patients with skeletal metastases.

PMID- 4364999
TI  - Hydrolysis of bradykinin by angiotensin-converting enzyme.

PMID- 4365000
TI  - [The role of ACTH in the regulation of cholesterol metabolism in the adrenal
      cortex].

PMID- 4365001
TI  - Comparison between fractional turnover rate of endogenous plasma triglycerides
      and of intralipid (intravenous fat tolerance test) in man.

PMID- 4365002
TI  - Plasma cyclic AMP and total catecholamines during acute myocardial infarction in
      man.

PMID- 4365003
TI  - Sex difference in the kinetics of triglyceride metabolism in normal and
      hypertriglyceridaemic human subjects.

PMID- 4365004
TI  - Relationship between plasma concentrations of angiotensin I, angiotensin II and
      plasma renin activity during cardio-pulmonary bypass in man.

PMID- 4365005
TI  - Galactose metabolism in a patient with hereditary galactokinase deficiency.

PMID- 4365006
TI  - Cycloheximide: a specific inhibitor of protein synthesis and intercellular ion
      transport in plant roots.

PMID- 4365007
TI  - Presence of the same types of nonhistone chromosomal proteins in different
      tissues.

PMID- 4365009
TI  - Muscarinic mediation of the biphasic temperature response to intrahypothalamic
      injections of carbachol in the cat.

PMID- 4365008
TI  - Carbohydrate components of plasma membrane of transitional epithelium of urinary
      tract.

PMID- 4365010
TI  - The cyclic AMP response to noradrenalin in young adult rat brain following post
      natal injections of 6-hydroxydopamine.

PMID- 4365011
TI  - A neuralizing influence of dibutyryl cyclic AMP on competent chick ectoderm.

PMID- 4365012
TI  - Short term effects of dimethylnitrosamine and methylmethanesulphonate on
      hydrolases of the rat.

PMID- 4365013
TI  - [An electrophysiologic analysis of the depressant effect of several derivatives
      of gamma-aminobutyric acid].

PMID- 4365014
TI  - [Comparative characteristics of sodium gamma-hydroxybutyrate, several of its beta
      substituted analogs and sodium alpha-hydroxyglutarate].

PMID- 4365015
TI  - [The effect of fentanyl on afferent systems].

PMID- 4365016
TI  - Use of restriction endonucleases in analyzing the genome of simian virus 40.

PMID- 4365017
TI  - [Clinical picture and expert testimony on work capacity in chronic occupational
      poisoning with unsaturated and chlorinated hydrocarbons].

PMID- 4365018
TI  - [General toxic action of perchloric acid].

PMID- 4365019
TI  - [Hygienic standardization of Aerosil dusts modified with butyl alcohol and
      dimethyldichlorosilane].

PMID- 4365020
TI  - [Dysplasia of the cervix uteri. Comparative study of different treatments].

PMID- 4365021
TI  - The usefulness of the relaxation response in the therapy of headache.

PMID- 4365022
TI  - [Carcinoma of the breast in males. Review of 29 cases].

PMID- 4365023
TI  - Clinical evolution of Japanese encephalitis.

PMID- 4365024
TI  - The Epstein-Barr virus and its relationship to infectious mononucleosis in Air
      Force recruits.

PMID- 4365025
TI  - Venereal disease in Vietnam: clinical experience at a major military hospital.

PMID- 4365026
TI  - [Influence of retrograde and transneural effects on the activity of thiamine
      pyrophosphate in the Golgi apparatus].

PMID- 4365027
TI  - [Influence of retrograde and transneural effects on the activity of thiamine
      pyrophosphate in the Golgi apparatus].

PMID- 4365028
TI  - Pediatric radiologic notes. Case no. 373. Mesenchymal hamartoma of the kidney in
      a neonate.

PMID- 4365029
TI  - Glomus tympanicum tumours: early diagnosis by arteriography.

PMID- 4365030
TI  - Association of the Golgi complex with the plasma membrane of amphibian embryonic
      cells.

PMID- 4365031
TI  - [Retropharyngeal abscess in an elderly patient].

PMID- 4365032
TI  - [Tumor as the cause of exudative otitis media].

PMID- 4365033
TI  - [Chronic infection of cell cultures by tick-borne encephalitis virus: ribonucleic
      acid characteristics].

PMID- 4365034
TI  - [The effect of p-fluorophenylalanine on the synthesis of virus-specific RNA of
      different sedimentation classes in cells infected by Newcastle disease virus].

PMID- 4365035
TI  - [The morphology and morphogenesis of oncogenic RNA-containing virus (strain LPV)
      obtained from man in human cell cultures].

PMID- 4365036
TI  - [The epidemiologic aspect of an outbreak of leukemia in a herd of baboons at the
      Sukhumi nursery].

PMID- 4365037
TI  - [Use of stress on the reticuloendothelial system and hyperthemia for enhancement
      of tumor heterogenization by viruses and direct viral oncolysis].

PMID- 4365038
TI  - [The sensitivity of embryonal cell cultures from rats and mice of different lines
      the transformation-destructive effect of mouse sarcoma virus].

PMID- 4365039
TI  - [The frequency of development of associated infections in acute respiratory
      diseases].

PMID- 4365040
TI  - [Genetic markers of clonal variants of adenovirus type 1].

PMID- 4365041
TI  - [Reconstruction of the hand in epidermolysis bullosa].

PMID- 4365042
TI  - [Therapeutic effect of lipiodol and hysterosalpingography in female sterility].

PMID- 4365043
TI  - [Changes in the reactivity of the anterior tibial muscle in cats following action
      of some piperazine derivatives].

PMID- 4365044
TI  - Release and metabolism of prostaglandins in lung tissue.

PMID- 4365045
TI  - Visna virus-induced fusion of continous simian kidney cells.

PMID- 4365046
TI  - [Treatment of primary hyperlipoproteinemia type IIa and IIb with dextrothyroxine
      (author's transl)].

PMID- 4365047
TI  - [Kidney and calcium metabolism. Physiology and pathophysiology of renal calcium
      excretion].

PMID- 4365048
TI  - [Clinical significance of immunoglobulin E].

PMID- 4365049
TI  - Properties of afferent nerve impulses originating from a neuroma.

PMID- 4365050
TI  - [Latent adrenal gland insufficiency in ketonemic vomiting].

PMID- 4365051
TI  - The blockade of angiotensin action by 8-leu-angiotensin on the guinea-pig aortic
      strip.

PMID- 4365052
TI  - Drinking elicited by polyethylene glycol and isoproterenol reduced by antiserum
      to angiotensin II.

PMID- 4365053
TI  - Thrombocythaemia. Familial occurrence and transition into blastic crisis.

PMID- 4365054
TI  - A look at restraining practices and the use of psychotropic drugs.

PMID- 4365055
TI  - Which patient for which therapeutic group.

PMID- 4365056
TI  - At what level does the psychiatric clinical specialist practice?

PMID- 4365057
TI  - An expanded role for psychiatric nursing personnel: psychological evaluation and
      interpersonal care.

PMID- 4365059
TI  - Everybody gets angry sometime.

PMID- 4365058
TI  - Sterilization and therapeutic abortion counseling for the mentally retarded.

PMID- 4365060
TI  - Nursing students and their learning experiences in geriatrics.

PMID- 4365061
TI  - Prospects for contraception.

PMID- 4365062
TI  - Speaking out on: approaching a sensible position on public facilities and
      treatment resources for the mentally ill and mentally retarded?

PMID- 4365063
TI  - Determination of the kinetic constants of fructose transport and phosphorylation
      in the perfused rat liver.

PMID- 4365064
TI  - The action of melittin on phosphatide multibilayers as studied by infrared
      dichroism and spin labeling. A model approach to lipid-protein interactions.

PMID- 4365065
TI  - [Biochemical heterogeneity of brain microstructures].

PMID- 4365066
TI  - [Heart rate and respiration in newborn infants in different sleep stages].

PMID- 4365067
TI  - [Heterogeneity of the amino acid composition of cytochrome C].

PMID- 4365068
TI  - [Electron microscopic study of the sturgeon olfactory organ].

PMID- 4365069
TI  - Ultrasonic patterns of tumors of the liver.

PMID- 4365070
TI  - Proceedings: Pharmacological aspect of enzymes related to cyclic AMP.

PMID- 4365071
TI  - Proceedings: Effects of prostaglandin E on the inhibitory responses of taenia
      coli produced by electrical stimulation.

PMID- 4365072
TI  - Proceedings: Studies on food poisoning due to Clostridium welchii.

PMID- 4365073
TI  - Proceedings: Inhibition of platelet cyclic AMP phosphodiesterase and platelet
      aggregation.

PMID- 4365074
TI  - Proceedings: Effect of antidiuretic hormone on cyclic adenosine 3',5'
      monophosphate levels in rat kidney cells in culture.

PMID- 4365075
TI  - Proceedings: Fluorometric determination of cyclic AMP using dansyl chloride.

PMID- 4365076
TI  - Proceedings: Pharmacological analyses of action of DBc-AMP on the central nervous
      system of conscious dogs.

PMID- 4365077
TI  - Proceedings: Excretion of cyclic AMP into duct saliva from the salivary gland.

PMID- 4365078
TI  - Proceedings: Comparison of cardiovascular effects of dibutyryl cyclic AMP
      (DBcAMP) and cyclic AMP (cAMP).

PMID- 4365079
TI  - Proceedings: Regional differences in the sensitivity to several bioactive
      peptides in the venous system of dog.

PMID- 4365080
TI  - Proceedings: Effects of trazodone on monoamine metabolism in rat brain, as
      related to the paradoxical sleep suppressing effects.

PMID- 4365081
TI  - Proceedings: Physiological and pharmacological properties of bradikinin-sensitive
      dorsal horn neuron of the spinal cord.

PMID- 4365082
TI  - Proceedings: Studies of the "whorled body" in the adrenocortical cell.

PMID- 4365083
TI  - Proceedings: Pharmacological studies on ganglionic transmission: effects of
      acetylcholine and catecholamines.

PMID- 4365084
TI  - Proceedings: Effects of antispasmodics on phosphodiesterase.

PMID- 4365085
TI  - Proceedings: The effects of some drugs on the Ca++-uptake by microsomal fraction
      from guinea pig taenia coli.

PMID- 4365086
TI  - Transcellular fluid formation and vascular permeability increase by angiotensins.

PMID- 4365087
TI  - Cellular and subcellular localization of 3H-oestradiol in the oviduct and uterus
      of the neonatal rat.

PMID- 4365088
TI  - Detergent dispersion of adenylate cyclase from partially purified rat liver
      plasma membranes.

PMID- 4365089
TI  - Cyclic 3',5'-nucleotide phosphodiesterase. Distribution and developmental changes
      of the enzyme and its protein activator in mammalian tissues and cells.

PMID- 4365090
TI  - Effect of temperature upon inhibition by substrate of lactate dehydrogenase
      isoenzymes from a poikilotherm.

PMID- 4365091
TI  - Pilot experiments with EB virus in owl monkeys (Aotus trivirgatus). I
      Reticuloproliferative disease in an inoculated animal.

PMID- 4365092
TI  - Primary immunodeficiency diseases and cancer: the immunodeficiency-cancer
      registry.

PMID- 4365093
TI  - Sensitivity to EBV superinfection and IUdR inducibility of hybrid cells formed
      between a sensitive and a relatively resistant Burkitt lymphoma cell line.

PMID- 4365094
TI  - Immunogenicity and immunosensitivity of SV40-transformed cells with different
      oncogenic potentials.

PMID- 4365095
TI  - Analysis of minimal functions of simian virus 40. I. Oncogenic transformation of
      Syrian hamster kidney cells in vitro by photodynamically inactivated SV40.

PMID- 4365096
TI  - Repair of radiation and chemical damage to DNA in human cells.

PMID- 4365097
TI  - Triglyceride metabolism in skeletal muscle from normal and dystrophic mice.

PMID- 4365098
TI  - Quinones of Brevibacterium.

PMID- 4365099
TI  - Current concepts of therapy in mushroom intoxication.

PMID- 4365100
TI  - Studies on the ribosomes of a thiopeptin-resistant mutant of Escherichia coli.

PMID- 4365102
TI  - Isolation of cold-sensitive mutants of simian virus 40.

PMID- 4365101
TI  - Intestinal resistance in the experimental enteric infection of mice with a mouse
      adenovirus. 3. Suppressive effect of cyclophosphamide on the establishment and
      duration of the intestinal resistance.

PMID- 4365103
TI  - Cyclic nucleotide levels in incubations of guinea pig trachea.

PMID- 4365104
TI  - Modulation by cyclic AMP in vitro of liver plasma membrane (Na+--K+)-ATPase and
      protein kinases.

PMID- 4365105
TI  - 5-Keto-D-fructose. 8. Synthesis of 5-keto-D-fructose 1,6-bisphosphate and some of
      its properties.

PMID- 4365106
TI  - Regulation of gluconeogenesis by alanine.

PMID- 4365107
TI  - Polysaccharides of the cellular slime mold. I. Extracellular polysaccharides in
      growth phase of Dictyostelium discoideum.

PMID- 4365108
TI  - Disulphide groups of gonadotropin receptors are essential for specific binding of
      human chorionic gonadotropin.

PMID- 4365109
TI  - Ultrastructlral and histochemical observations of the external epithelium of
      echinoderm tube feet.

PMID- 4365110
TI  - Myodifferentiation in the carotid artery of the adult sheep: an ultrastructural
      study.

PMID- 4365111
TI  - Effect of glucose loading on blood sugar and on the histology of the pancreatic
      islets in Clarias batrachus (Linn.).

PMID- 4365113
TI  - Avian pox in a mourning dove.

PMID- 4365112
TI  - An electron microscopic study of the intraepidermal innervation of human glabrous
      skin.

PMID- 4365114
TI  - Anti-herpesvirus action of isoprinosine.
AB  - Anti-herpesvirus effects of Isoprinosine were found to be condition-dependent in
      vitro and in vivo. A herpes type 1 strain, grown in primary rabbit kidney cells,
      was not susceptible to Isoprinosine when cytopathic effect was evaluated, but was
      modestly inhibited when plaque-forming methocel overlay was used in the same cell
      line. However, the growth of a herpes type 2 strain was inhibited by Isoprinosine
      in this system when cytopathic effect was evaluated. Both viruses produced an
      encephalitis in hamsters after application by corneal abrasion. The encephalitis
      produced by a 1.5 mean lethal dose of herpesvirus was strikingly suppressed by
      large doses of Isoprinosine given ad libitum in the drinking water; this
      protection was not seen, however, at 15 mean lethal doses. Anti-herpes effects of
      Isoprinosine were suppressed by additional treatment with cortisone, both in
      tissue culture and in vivo. Isoprinosine, in the absence of virus infection,
      produced significant effects on the metabolism, structure, and function of brain
      ribosomes. In vivo, RNA components were labeled more rapidly and gave up their
      radioactivity more slowly after treatment with Isoprinosine. This enhanced
      cytoplasmic radioactivity was associated with a loss of incorporated
      radioactivity located in the nucleus and an increase in radioactivity located in
      a ribonucleo-protein fraction >4S and <18S. Ribosomes from treated brains gave
      physical evidence of being more compact (less orthochromic). Isoprinosine
      treatment increased the incorporation of [(14)C]phenylalanine into nascent
      protein in a cell-free system examining protein synthesis in brain polyribosomes.
      The addition of the exogenous messenger ribonucleic acid, polyuridylic acid,
      produced a significant age-dependent inhibition in the incorporation of [(14)C]
      phenylalanine. This inhibition was significantly greater when ribosomes were
      isolated from animals pretreated with Isoprinosine. These and other observations
      suggest that the Isoprinosine stimulation of host ribonucleic acid metabolism may
      be coupled to the production of ribosomes that do not effectively translate
      exogenous messenger ribonucleic acid.

PMID- 4365115
TI  - Efficacy of trimethoprim and sulfamethoxazole in the prevention and treatment of
      Pneumocystis carinii pneumonitis.
AB  - A combination of trimethoprim and sulfamethoxazole was effective in the
      prevention and treatment of Pneumocystis carinii pneumonitis in cortisonetreated
      rats. Although all of 15 untreated rats died with P. carinii pneumonitis, none of
      15 given trimethoprim-sulfamethoxazole prophylactically acquired the infection.
      After P. carinii pneumonitis was established, 9 of 14 rats recovered after
      treatment with trimethoprim-sulfamethoxazole compared with only 2 of 14 treated
      with pentamidine isethionate. Rifampin and clindamycin, separately or in
      combination with pentamidine, were ineffective in the prevention and treatment of
      P. carinii infection.

PMID- 4365116
TI  - Susceptibility of 1,500 isolates of Pseudomonas aeruginosa to gentamicin,
      carbenicillin, colistin, and polymyxin B.
AB  - A series of 1,500 strains of Pseudomonas aeruginosa was collected from a variety
      of sources to provide a group of strains which would truly represent the species.
      All of them were pyocine typed, and a wide range of types was included among the
      isolates from each source. The gentamicin, carbenicillin, colistin, and polymyxin
      minimal inhibitory concentration of each strain was measured by the agar dilution
      method employing the Steers inocula replicator. Over 99% of strains were
      inhibited by 8 mug of gentamicin per ml, by 256 mug of carbenicillin per ml, and
      by 4 mug of colistin per ml. The small number of strains more resistant to each
      antibiotic comprised a variety of different pyocine types. Few strains were found
      to be susceptible to tetracycline, chloramphenicol, kanamycin, or streptomycin at
      the single concentration tested.

PMID- 4365117
TI  - Inhibition of Sindbis virus replication in HeLa cells by poliovirus.
AB  - Concomitant infection of HeLa cells with poliovirus and Sindbis (SB) virus
      allowed replication of poliovirus only. The poliovirus-induced interference with
      the replication of SB virus was dependent partially on the multiplicity of SB
      virus used for infection. The observed interference was not sensitive to
      guanidine. Translation, but not replication of poliovirus, appears to be needed
      for the restriction of SB virus. Superinfection of SB virus-infected cultures
      with poliovirus was followed by inhibition of protein, but not by viral
      ribonucleic acid (RNA) synthesis. Polyribosomes present in SB virus-infected
      cells were disaggregated subsequent to superinfection. The nascent SB viral RNAs
      synthesized in cells subsequent to superinfection were not associated with the
      ribosomal structures. These results indicate that the block in protein synthesis,
      possibly at the level of initiation, may be the basis of the observed
      interference.

PMID- 4365118
TI  - Model studies in terpene biosynthesis.

PMID- 4365119
TI  - Nitrite in meat. Effect of various compounds on loss of nitrite.

PMID- 4365120
TI  - Discharge from hospital: the problem of adjustment.

PMID- 4365121
TI  - Culture of hepatitis B virus on a human cell line of hepatic origin. Preliminary
      results.

PMID- 4365122
TI  - Morphometric study of the ultrastructure of human alcoholic fatty liver.

PMID- 4365123
TI  - Letter: Recognition of structural domains in globular proteins.

PMID- 4365124
TI  - Specific immunodiagnosis of hepatocellular carcinoma by leucocyte adherence
      inhibition.
AB  - The leucocyte adherence inhibition test provides a rapid, reliable, and specific
      technique for the immunodiagnosis of primary hepatocellular carcinoma (malignant
      hepatoma). The patient's blood leucocytes are tested in vitro for cell-mediated
      immunity against tumour-associated antigens and the serum is tested for blocking
      factor which interferes with the immunological reaction. Specific reactivity of
      both leucocytes and serum was consistently detected in patients with malignant
      hepatoma, and negative reactions were obtained in other liver diseases including
      secondary tumours of the liver. The test has provided positive evidence for the
      presence of hepatoma when more conventional methods gave doubtful or negative
      results. A positive result preceded the clinical appearance of tumour by up to
      three years in two patients.

PMID- 4365125
TI  - Unsuspected cytomegalic mononucleosis.

PMID- 4365126
TI  - Electrophysiological properties of the giant neurons of the leech subesophageal
      ganglion.

PMID- 4365127
TI  - Calcium and Purkinje cells in a perfused frog cerebellum.

PMID- 4365128
TI  - Recovery of neuronal activity and high-energy compound level after complete and
      prolonged brain ischemia.

PMID- 4365129
TI  - Vascular lesions in the hand. Current management.

PMID- 4365130
TI  - Ultrastructure of chondrosarcoma.

PMID- 4365131
TI  - [Studies of calcium phosphate metabolism in a case of McCune-Albright syndrome
      with phosphate diabetes (author's transl)].

PMID- 4365132
TI  - [Role of prostaglandins in the skin].

PMID- 4365133
TI  - Inclusion of proteins of the cytoplasm of Zajdela hepatoma in the chromatin of
      rat liver cells.

PMID- 4365134
TI  - Photoconversions of bacteriochlorophylls and cytochromes in Chromatium
      chromatophores and cells under reducing conditions.

PMID- 4365135
TI  - The transsynaptic relationship between dopamine and serotonin in the caudate
      nucleus of cats.

PMID- 4365136
TI  - [Composition of nutrient media and toxin formation of Clostridium perfringens].

PMID- 4365137
TI  - [Use of ensheathing prosthesis in cases of odontogenesis imperfecta hereditaria].

PMID- 4365138
TI  - [Current diabetology and its prospects].

PMID- 4365139
TI  - Fine structure of rat islet cell tumors induced by streptozotocin and
      nicotinamide.

PMID- 4365140
TI  - [Persistence of viruses on surface areas and use of UV-irradiation in virus
      disinfection].

PMID- 4365141
TI  - Aldosterone secretion in the enucleated rat adrenal during salt retention.

PMID- 4365142
TI  - Prostaglandin receptors in the human, monkey and hamster uterus.

PMID- 4365143
TI  - A comparison of cyclic nucleotide levels in plasma and cells of rat and human
      blood.

PMID- 4365144
TI  - Prevention of illness from rhinovirus infection by a topical interferon inducer.

PMID- 4365145
TI  - Proceedings: An explanation of the antiandrogenic properties of a non-steroidal
      compound, SCH 13521.

PMID- 4365146
TI  - Proceedings: Thyroid-stimulating hormone binding to human thyroid membranes and
      solubilized receptors.

PMID- 4365147
TI  - Proceedings: Corticosteroid feedback at the pituitary level.

PMID- 4365148
TI  - Proceedings: Pituitary adrenocorticotrophic activity after adrenalectomy and
      adrenal enucleation in the rat.

PMID- 4365149
TI  - Proceedings: Effect of human chorionic gonadotrophin on in-vivo levels of cyclic
      AMP in rabbit ovaries.

PMID- 4365150
TI  - The gonadotrophins and their releasing factors.

PMID- 4365151
TI  - Hypothalamic control of gonadotrophin and prolactin secretion, implications for
      fertility control.

PMID- 4365152
TI  - Hypoglycemia and insular hyperplasia: review of 148 cases.
AB  - On the bases of personal experience and the series of 148 cases from an
      international inquiry and a review of the literature, the relation between
      insular hyperplasia and hypoglycemia was examined. The fundamental points in this
      investigation included: age, diagnostic investigations, histological findings and
      postoperative results. The data on the patients with insular hyperplasia
      indicates that 83% were of adult age. Insular hyperplasia was the only abnormal
      factor determined to be present. Through treatment a high percentage of cases
      (71%) was cured. From a practical surgical point of view, differentiation between
      occult insulomas and insular hyperplasia is not critical. Consequently, good
      results can be achieved in botlh diseases by practicing a progressive blind
      resection guided by examination of the operated specimen and by intra-operative
      blood sugar levels.

PMID- 4365153
TI  - Cholesteryl ester-rich inclusions from human aortic fatty streak and fibrous
      plaque lesions of atherosclerosis. I. Crystalline properties, size and internal
      structure.
AB  - Cholesteryl esters, the major lipid in the lesions of human atherosclerosis,
      occurred in fatty streaks and fibrous plaques from 42 adults as spherical
      inclusions whose diameters averaged 1.99 +/- 0.48 and 2.16 +/- 0.62 mu,
      respectively, and which with polarizing light microscopy resolved into a mixture
      of various proportions of anisotropic and isotropic forms. Anisotropic forms had
      diameters of 1.9 +/- 0.4 mu, uniaxial-like symmetry with a formee cross image, a
      whitish gray interference color under cross polarizer and analyzer, second order
      blue and first order yellow interference colors with a tint plate, a
      birefringence of 0.0412 +/- 0.0054 and a refractive index of 1.559 +/- 0.0014.
      Their probable structural organization is primarily a lyotropic smectic mesophase
      (liquid crystal) of cholesteryl esters secondarily organized into multiple
      concentric lamellae. Isotropic forms had diameters of 2.3 +/- 0.6 mu and were
      optically inactive irrespective of their orientation. At 23 C, fatty streak
      inclusions from 21 subjects averaged significantly higher in the proportion of
      anisotropic forms, 85.5 +/- 9.3%, than did fibrous plaque inclusions from 21
      subjects, which had 32.4 +/- 16.3% anisotropic forms (P < 0.01).

PMID- 4365154
TI  - Responses to exogenous adenosine 3',5'-monophosphate of cardiac output and blood
      flow in the renal, superior mesenteric and carotid arteries in anesthetized dogs.

PMID- 4365155
TI  - Effect of corticosterone and cortisol on corticosteroidogenesis in isolated rat
      adrenal cells.

PMID- 4365156
TI  - Studies on plasma membranes. XXI. Inhibition of liver plasma membrane enzymes by
      tumour-promoting phorbolester, mitotic inhibitors and cytochalasin B.

PMID- 4365157
TI  - Proceedings: Effect of calcium ion on renin release from renal cortex slices and
      isolated renin granules.

PMID- 4365158
TI  - Proceedings: Acute toxicity of cyclic AMP in mice.

PMID- 4365159
TI  - Proceedings: Metabolism of N6,02'-dibutyryl-3', 5'-cyclic-AMP (DBcAMP).

PMID- 4365160
TI  - Proceedings: Effects of cholinergic drugs on the synaptic transmission in
      isolated spinal cord-nerve-muscle preparation of the bullfrog.

PMID- 4365161
TI  - Proceedings: Influence of morphine on ACTH secretion in the rat.

PMID- 4365162
TI  - Proceedings: Mechanism of relaxation of smooth muscle by 3-isopropyl-5,7
      dipiperidinomethyltropolone hydrochloride (IDPT).

PMID- 4365163
TI  - Response of plasma aldosterone to postural change, diuretica, angiotensin II,
      sodium restriction or loading and prostaglandin.

PMID- 4365164
TI  - [Therapeutic prospects with a sulfoglycopeptide (sulglycotide) in gastroduodenal
      ulcer].

PMID- 4365165
TI  - Coronavirus infections in military recruits. Three-year study with coronavirus
      strains OC43 and 229E.

PMID- 4365166
TI  - Melanin: a normal component of human eosinophils.

PMID- 4365167
TI  - The effects of sodium chromate on the proximal tubules of the rat kidney. Fine
      structural damage and lysozymuria.

PMID- 4365168
TI  - Effect of renin immunization on mercuric chloride and glycerol-induced renal
      failure.

PMID- 4365169
TI  - Letter: Down's syndrome, hypothyroidism, and diabetes mellitus.

PMID- 4365170
TI  - Temperature-sensitive pleiotropic revertants from a mutant in the arom gene
      cluster of Neurospora crassa.
AB  - Genetical and biochemical studies have been performed with revertants induced in
      a polyaromatic mutant (No. 58) in the arom gene cluster of Neurospora crassa. In
      addition to complete and partial revertants able to grow on minimal at both 25
      degrees and 35 degrees , temperature-sensitive revertants capable of growth on
      minimal at 25 degrees but not at 35 degrees have been recovered. One of these
      revertants has been shown to lack biosynthetic dehydroquinase activity at both
      temperatures (utilizing the inducible catabolic isozyme for growth at 25 degrees
      ), to have dehydroshikimate reductase activity only at 25 degrees , and to form
      an arom aggregate having a molecular weight approximately one-half that of wild
      type. These results are interpreted as indicating that pleiotropic mutants in the
      arom gene cluster can result from missense mutations, as well as from nonsense
      mutations as indicated in previous studies.

PMID- 4365171
TI  - Malignancy in pleomorphic adenoma. A clinical and microspectrophotometric study.

PMID- 4365172
TI  - Diagnostic tests of facial nerve function.

PMID- 4365173
TI  - Neoplastic involvement of the facial nerve.

PMID- 4365174
TI  - [Studies on epinephrine- and norepinephrine-stimulated FFA (Free Fatty Acid)
      mobilization in vitro and in human fatty tissue from various regions].

PMID- 4365175
TI  - Prostaglandins and inflammation.

PMID- 4365176
TI  - Comparison of the PGE1 and catecholamines influence on the active transport of
      sodium.

PMID- 4365177
TI  - Reference values for cord blood lipid and lipoprotein concentrations.

PMID- 4365178
TI  - Intracellular hydroxylation of non-helical protocollagen to form triple-helical
      procollagen and subsequent secretion of the molecule.

PMID- 4365179
TI  - Chromatographic analysis of aminoacyl tRNAs of poliovirus infected HEp-2 cells.

PMID- 4365180
TI  - Studies on seed-oil triglycerides. Triglyceride biosynthesis and storage in whole
      seeds and oil bodies of Crambe abyssinica.

PMID- 4365181
TI  - Mossbauer effect and electron spin resonance of the (iron)4-sulfur clusters of
      ferredoxin from Clostridium pasteurianum.

PMID- 4365182
TI  - Protein kinase activity in African swine fever virus.

PMID- 4365183
TI  - Studies of glutamate dehydrogenase: chemical modification and quantitative
      determination of tryptophan residues.

PMID- 4365184
TI  - Hemadsorption cell-counting assay of interferon.

PMID- 4365185
TI  - Foot-and-mouth disease virus: plaque reduction neutralization tests.

PMID- 4365186
TI  - ATPase and GTPase activities isolated from rat liver ribosomes.

PMID- 4365187
TI  - Neutralizing activity in the serum and oesophageal-pharyngeal fluid of cattle
      after exposure to foot-and-mouth disease virus and subsequent re-exposure.

PMID- 4365188
TI  - The intracellular location of pyruvate carboxylase in rat liver.

PMID- 4365189
TI  - The reactivation of C55-isoprenoid-alcohol-phosphokinase apoprotein by lipids.
      Evidence for lipid hydration in lipoprotein function.

PMID- 4365190
TI  - The surface energetics of asbestos minerals.

PMID- 4365191
TI  - [Physiology and physiopathology of ketone bodies II. Regulation of ketone bodies
      formation and their utilization].

PMID- 4365192
TI  - [Glucagon and its effect on the gastrointestinal tract].

PMID- 4365193
TI  - Adenosine 3',5'-cyclic phosphate, lipolysis and oxygen consumption in brown
      adipose tissue from newborn rabbits. Effect of cervical sympathectomy and of
      noradrenalin and theophylline in vitro, and the partial purification of an
      adenosine 3',5'-cyclic phosphate-dependent protein kinase.

PMID- 4365194
TI  - [Primary and secondary aldosteronism in hypertension].

PMID- 4365195
TI  - [Electron microscopic evidence of intraepithelial axons in the epidermis of the
      eyelid in the guinea pig].

PMID- 4365196
TI  - Enhancement of the sensitivity of the immunodiffusion reaction in the detection
      of antibody against bovine adenoviruses.

PMID- 4365197
TI  - Enhancement in excitability properties of mouse neuroblastoma cells cultured in
      the presence of dibutyryl cyclic AMP.

PMID- 4365198
TI  - Aromatic sulfonic acids as viral inhibitors. Structure-activity study using
      rhino, adeno 3, herpes simplex, and influenza viruses.

PMID- 4365199
TI  - Angiotensin II analogs. 5. (2-Glycine)angiotensin II and related analogs.

PMID- 4365200
TI  - Septic arthritis of the hip joint secondary to umbilical artery catheterization
      associated with transient femoral and sciatic neuropathy.

PMID- 4365201
TI  - Potential antidiabetics. 9. Biological activity of some pyrazoles.

PMID- 4365202
TI  - [Primary liver carcinoma a clinical study].

PMID- 4365203
TI  - [Liver findings in primary hyperlipoproteinemia (HLP)].

PMID- 4365204
TI  - Studies of malformation syndromes of man 33: the FG syndrome. An X-linked
      recessive syndrome of multiple congenital anomalies and mental retardation.

PMID- 4365205
TI  - Protein kinase-catalyzed phosphorylation of muscle sarcolemma.

PMID- 4365206
TI  - Differences in active center reactivity of trypsin homologs. Specific
      inactivation of thrombin by nitrophenyl p-amidinophenylmethanesulfonate.

PMID- 4365207
TI  - Control of respiration by the mitochondrial phosphorylation state.

PMID- 4365208
TI  - Distribution of enzymes of glycogen metabolism and calcium uptake in skeletal
      muscle.

PMID- 4365209
TI  - Hyperlipoproteinemia type V: biochemical observations in two cases.

PMID- 4365210
TI  - Glucosylceramide in plasma of patients with Niemann-Pick disease.

PMID- 4365211
TI  - The use of synthetic inhibitors to study the interaction of nicotinamide adenine
      dinucleotide with yeast alcohol dehydrogenase.

PMID- 4365212
TI  - The renin-angiotensin system in the fetal lamb.

PMID- 4365213
TI  - Biochemical changes during progesterone-induced maturation in Xenopus laevis
      oocytes.

PMID- 4365214
TI  - Enzyme catalysis: conflicting requirements of substrate access and transition
      state affinity.

PMID- 4365215
TI  - Receptor-binding assay of chemically modified insulins. Comparison with in vitro
      and in vivo bioassays.

PMID- 4365216
TI  - [Alpha1-foetoprotein in malignant tumors (author's transl)].

PMID- 4365217
TI  - Ocular manifestations of systemic disease.

PMID- 4365218
TI  - [Cytarabine, a reliable antiviral drug?].

PMID- 4365219
TI  - Plasma cyclic adenosine 3'5'-monophosphate (AMP) levels in acute myocardial
      infarction.

PMID- 4365220
TI  - Donovanosis: a morphologic study.

PMID- 4365221
TI  - The adrenergic innervation of the gastrointestinal tract.

PMID- 4365222
TI  - The maintenance of liver cells in vitro for virological and other studies.

PMID- 4365223
TI  - [Results of virological diagnosis of 21 cooperating medico-virological
      examination centers in the Federal Republic of Germany. 1972 annual report. 14].

PMID- 4365224
TI  - [Postoperative peripheral pareses].

PMID- 4365225
TI  - [In-vitro inhibition of renin secretion by angiotensin II].

PMID- 4365226
TI  - Ultrastructural and histochemical studies of a newly recognized form of systemic
      mucopolysaccharidosis. (Maroteaux-Lamy syndrome, mild phenotype).

PMID- 4365227
TI  - Letter: Postmortem formation of giant endothelial vacuoles in Schlemm's canal.

PMID- 4365228
TI  - Different degradation rates of alkylated RNA protein and lipids in normal and
      tumor cells.

PMID- 4365229
TI  - Effect of N-methyl-N-nitrosourea on the protein-synthesizing system in mouse
      liver and hepatoma 22a cells.

PMID- 4365230
TI  - Cytoplasmic glucocorticoid-binding proteins in glucocorticoid-unresponsive human
      and mouse leukemic cell lines.

PMID- 4365231
TI  - The catabolism of alpha1-fetoprotein and albumin in rats bearing Morris hepatoma
      7777.

PMID- 4365232
TI  - Diurnal distribution of motor activity and feeding during growth of tumors.

PMID- 4365233
TI  - A comparison of phenylalanyl-tRNA synthetase from rat liver and a minimal
      deviation hepatoma.

PMID- 4365234
TI  - Evidence for bile acid synthesis by transplantable hepatomas.

PMID- 4365235
TI  - Activity and hormone responsiveness of adenyl cyclase during induction of tumors
      in rat liver with 3'-methyl-4-dimethylaminoazobenzene.

PMID- 4365236
TI  - Letter: Classification of mouse tumor viruses.

PMID- 4365237
TI  - A fast method of analysis of the 5' terminal nucleotides of
      deoxyribooligonucleotides.

PMID- 4365238
TI  - Isolation and characterisation of a mitochondrially synthesized precursor protein
      of cytochrome oxidase.

PMID- 4365239
TI  - On the nature of argR mutations is Saccharomyces cerevisiae.

PMID- 4365240
TI  - Biological and immunological activity of fructose 1,6-bisphosphatase. Effect of
      structural changes on the quantitative displacement radioimmunoassay of fructose
      1,6-bisphosphatase.

PMID- 4365241
TI  - Purification and properties of N-acetylglucosamine kinase from human gastric
      mucosa.

PMID- 4365242
TI  - Isotope effects and hydrogen transfer during simultaneous metabolism of ethanol
      and cyclohexanone in rats.

PMID- 4365243
TI  - Benefit from adrenocorticotrophin in myasthenia gravis.
AB  - Twenty-one of 29 patients suffering from myasthenia gravis derived benefit from a
      short intensive course of adrenocorticotrophin (ACTH). The mean duration of
      benefit was approximately six months. The best results were obtained in patients
      with a short history of myasthenia. Transient deterioration during the course of
      injections was encountered in some cases but necessitated assisted respiration
      only in patients with severe generalized weakness before treatment.

PMID- 4365244
TI  - Micturition symptoms in frontal tumours.
AB  - In a series of 50 consecutive tumours involving the frontal lobes, seven cases
      (14%) were found who exhibited the syndrome, first described by Andrew and Nathan
      in 1964, of frequency of micturition, urgency, and incontinence causing distress
      to the patient. This suggests that this syndrome may occur rather more commonly
      than those authors had indicated. In 100 consecutive intracranial tumours, no
      instances were found with non-frontal tumours, indicating that the syndrome may
      be of localizing value.

PMID- 4365245
TI  - Collagen films: effect of cross-linking on physical and biological properties.

PMID- 4365246
TI  - Epinephrine blockade of ribonuclease activity stimulation in lymphoid organs by
      cortisone and prostaglandin EI.

PMID- 4365247
TI  - Molecular aspects for the metabolic regulation of the nicotinamide adenine
      dinucleotide-dependent D(-)-lactate dehydrogenase from Leuconostoc.

PMID- 4365248
TI  - Reaction of cytidine with ethylating agents.

PMID- 4365249
TI  - Reaction of adenosine with ethylating agents.

PMID- 4365250
TI  - Regulation of adenylyl cyclase from isolated pancretic islets by prostaglandins
      and guanosine 5'-triphosphate.

PMID- 4365251
TI  - Characterization of the interaction between 17 beta-estradiol and its cytoplasmic
      receptor in the rat anterior pituitary gland.

PMID- 4365252
TI  - Proton magnetic resonance studies of Desulfovibrio cytochromes c3.

PMID- 4365253
TI  - [Chemodectomas in otorhinolaryngology (author's transl)].

PMID- 4365254
TI  - The inhibition of avian myeloblastosis virus deoxyribonucleic acid polymerase by
      synthetic polynucleotides.

PMID- 4365255
TI  - [Residual moisture of lyophilized biopreparations and its influence on
      effectiveness].

PMID- 4365256
TI  - [Familial type 3 hyperlipoproteinemia].

PMID- 4365257
TI  - Ribonucleic acid synthesis of vesicular stomatitis virus. VI. Correlation of
      defective particle RNA synthesis with standard RNA replication.

PMID- 4365258
TI  - Enhanced phosphatidylinositol labelling in rat parotid fragments exposed to alpha
      adrenergic stimulation.
AB  - 1. Adrenergic agonists provoke a marked increase in labelling of
      phosphatidylinositol in fragments of rat parotid gland. 2. Adrenaline and
      phenylephrine (an adrenergic alpha-agonist) are effective stimulants, but
      isoprenaline (an adrenergic beta-agonist) is relatively ineffective. 3. The
      response evoked by phenylephrine or adrenaline is prevented by prior incubation
      of the tissue with phenoxybenzamine (an alpha-receptor blocking agent), but not
      by prior incubation with pindolol (a beta-receptor blocking agent). 4. Adrenergic
      stimulation of phosphatidylinositol metabolism in parotid gland is therefore
      mediated through alpha-receptors, in common with the adrenaline-induced K(+)
      efflux. It is not linked to enzyme secretion, which is triggered by stimulation
      of beta-receptors. 5. It is suggested that the stimulation of phospholipid
      metabolism that occurs in several other tissues in the presence of adrenaline or
      noradrenaline may also involve alpha-receptors.

PMID- 4365259
TI  - Diminishing corticotrope capacity to release ACTH during sustained stimulation:
      the twenty-four hours after bilateral adrenalectomy in the rat.

PMID- 4365260
TI  - Metabolism of two adrenocorticotrophin analogues in the intestine of the rat.
AB  - 1. At 30min after oral administration unchanged Synacthen [corticotrophin-(1-24)
      tetracosapeptide] was found in the stomach but could not be detected in the lumen
      of the small intestine of the rat. 2. Synacthen and 41795-Ba {[d-Ser(1), Lys(17),
      Lys(18)]corticotrophin-(1-18)-octadecapeptide amide} were rapidly metabolized in
      vitro by both intestinal juice and everted pieces of small intestine. Peptide
      products were not found either in the intestinal tissue or in the fluid bathing
      the serosal tissue. 3. Glucose but not O(2) was necessary for the breakdown of
      the two adrenocorticotrophin analogues by everted tissue. 4. When the products
      obtained after partial digestion were chromatographically separated and
      identified, a pattern of breakdown emerged. The N-terminus of Synacthen and the
      Phe(7)-Arg(8) bond in both analogues were particularly labile. The d-serine N
      terminal residue of 41795-Ba conferred a marked protection to aminopeptidase
      action. 5. The relative susceptibilities of peptide bonds would have been
      difficult to predict on the basis of existing knowledge of the properties of
      enzymes of the small intestine.

PMID- 4365261
TI  - Stimulation of uridine incorporation in isolated bone cells by parathyroid
      hormone and cyclic AMP.

PMID- 4365262
TI  - [Craniopharyngioma ultrastructure. In vivo and in vitro study].

PMID- 4365263
TI  - Case records of the Massachusetts General Hospital. Weekly clinicopathological
      exercises. Case 27-1974. Recurrent abdominal pain and fever post cholecystectomy.

PMID- 4365265
TI  - Proceedings: Characterization of adrenocortical cell receptors for
      adrenocorticotrophin.

PMID- 4365266
TI  - Proceedings: Investigation of steroid-receptor interaction in pregnant sheep
      myometrium.

PMID- 4365267
TI  - Effects of silica and asbestos on cells in culture.

PMID- 4365264
TI  - Chemistry of animal venoms.

PMID- 4365268
TI  - [Fibrous silicates in animal experiments and cell-culture-morphological cell and
      tissue reactions according to different physical chemical influences].

PMID- 4365269
TI  - Proceedings: Functional affinities of the non-zoned adrenocortical tissue of the
      skink Tiliqua rugosa with the zone glomerulosa of the rat adrenal.

PMID- 4365270
TI  - Proceedings: Functional and morphological changes occuring in rat adrenal zona
      glomerulosa cells in monolayer culture.

PMID- 4365271
TI  - Inhibition of growth and respiration by visible and near-visible light.

PMID- 4365272
TI  - Proceedings: Thyroid function in the foetal calf.

PMID- 4365273
TI  - Proceedings: Adrenal function, oestrogen and the control of parturition in the
      guinea-pig.

PMID- 4365274
TI  - Proceedings: A correlated biochemical and morphological study of the development
      of adrenocorticotrophin-sensitive adenylate cyclase activity in foetal rabbit
      adrenals.

PMID- 4365275
TI  - Proceedings: Stimulation of melanocyte-stimulating hormone release in vitro by
      cyclic AMP.

PMID- 4365276
TI  - The effect of antibiotics on the growth and longevity of human diploid
      fibroblasts in vitro.

PMID- 4365277
TI  - An electron microscopic study of a single-cycle infection of Madin-Darby bovine
      kidney cells by infectious bovine rhinotracheitis virus.

PMID- 4365278
TI  - The radiology corner. Insulin-producing tumors of the pancreas.

PMID- 4365279
TI  - Isolation and properties of cytochrome a deficient mutants of Bacillus subtilis.

PMID- 4365280
TI  - Effect of prolonged chlorpromazine administration on the sleep of chronic
      schizophrenics.

PMID- 4365281
TI  - [Immunosuppression and cytomegalovirus infection. Animal experiments using
      cyclophospamidea].

PMID- 4365282
TI  - The formation of methylated bases in DNA by dimethylnitrosamine and its relation
      to differences in the formation of tumours in the livers of GR and C3HF mice.

PMID- 4365283
TI  - [Infectious bursitis of chickens (Gumboro disease) (review of the foreign
      literature)].

PMID- 4365284
TI  - EPR studies on the mechanism of biotransformation of tricyclic neuroleptics and
      antidepressants.

PMID- 4365285
TI  - Hydroxylation of 7-hydroxychlorpromazine by mushroom tyrosinase.

PMID- 4365286
TI  - Inhibition by phenothiazines of adenylate cyclase in adrenal and brain tissue.

PMID- 4365287
TI  - Effects of phenothiazines and phenothiazine metabolites on adenyl cyclase and the
      cyclic AMP response in the rat brain.

PMID- 4365288
TI  - Applied anatomical aspects of pain.

PMID- 4365289
TI  - Replication of temperature sensitive mutant of infectious bovine rhinotracheitis
      virus in the tissues of inoculated calves.

PMID- 4365290
TI  - Bovine abortion associated with Cytomegalovirus infection.

PMID- 4365291
TI  - [Clostridium perfringens as an indicator of water pollution as illustrated on the
      example of a harbor town in Turkey].

PMID- 4365292
TI  - Influence of heart rate on the reduction of sympathetic outflow produced by L
      dopa.

PMID- 4365293
TI  - Beta-adrenergic effects on rat myometrium: role of cyclic AMP.

PMID- 4365294
TI  - Pituitary 45 Ca ion uptake and release of ACTH, GH, and TSH: effect of verapamil.

PMID- 4365295
TI  - Effect of PGE1, indomethacin, and polyphloretin phosphate on toad bladder
      response to ADH.

PMID- 4365296
TI  - Acute intermittent porphyria, hypercholesterolaemia, and renal impairment.

PMID- 4365297
TI  - Sensitization to ragweed pollen in Bordetella pertussis-infected or vaccine
      injected mice.

PMID- 4365298
TI  - Effects of glucocorticosteroids on the urinary excretion of cyclic AMP and
      electrolytes by asthmatic children.

PMID- 4365299
TI  - An electron microscopic study of the giant cells in proliferative myositis.

PMID- 4365300
TI  - Proceedings: 231. Role of Ca++ and Mg++ in neuromuscular transmission and
      excitation of the radula protractor.

PMID- 4365301
TI  - Primary liver carcinoma.

PMID- 4365302
TI  - Proceedings: 261. On the projection from the parietal association cortex to the
      cerebellum.

PMID- 4365303
TI  - The bioavailability of iron sources and their utilization in food enrichment.

PMID- 4365304
TI  - Proceedings: 350. Aerobic dependence of synaptic transmission at the outer
      plexiform layer in the fish retina.

PMID- 4365305
TI  - Familial hypobetalipoproteinemia: report of a case with psychomotor retardation.

PMID- 4365306
TI  - Letter: Burkitt's lymphoma.

PMID- 4365307
TI  - Effects of cholecalciferol on bone formation and serum calcium, phosphate and
      magnesium in chicks.

PMID- 4365308
TI  - Viral probes of aging in the human diploid cell strain WI-38.

PMID- 4365309
TI  - Effect of angiotensin converting enzyme inhibition on renal autoregulation.

PMID- 4365310
TI  - 125I-glucagon binding and adenylate cyclase activation in the fetal rat heart.

PMID- 4365311
TI  - An improved immunoperoxidase technique for identifying SV40 V and T antigens by
      light microscopy.

PMID- 4365312
TI  - Effect of nonsteroidal antiinflammatory drugs on plasma protein-thyroxine
      interaction.

PMID- 4365313
TI  - Effect of hypophysectomy and pretreatment on uptake and retention of estradiol by
      the ovary.

PMID- 4365314
TI  - Depression of frog isolated spinal cord by morphine and antagonism by
      tetracosactin.

PMID- 4365315
TI  - Enhancement of interferon antiviral action in L-cells by cyclic nucleotides.

PMID- 4365316
TI  - Malignant fibrous histiocytoma of spermatic cord.

PMID- 4365317
TI  - Effect of adenosine 3',5'-cyclic monophosphate on the morphogenesis of fruit
      bodies of Schizophyllum commune.

PMID- 4365318
TI  - Cyclophosphamide in disseminated bronchial carcinoma.

PMID- 4365319
TI  - Relationships between antimicrobial activities and chemical structures of reduced
      products of viomycin.

PMID- 4365320
TI  - [Efficacy and limits of diagnostic procedures in hypertension].

PMID- 4365321
TI  - Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the
      synthesis of three groups of viral proteins.
AB  - Based on evidence that 50% of herpes simplex 1 DNA is transcribed in HEp-2 cells
      in the absence of protein synthesis we examined the order and rates of synthesis
      of viral polypeptides in infected cells after reversal of cycloheximide- or
      puromycin-mediated inhibition of protein synthesis. These experiments showed that
      viral polypeptides formed three sequentially synthesized, coordinately regulated
      groups designated alpha, beta, and gamma. Specifically: (i) The alpha group,
      containing one minor structural and several nonstructural polypeptides, was
      synthesized at highest rates from 3 to 4 h postinfection in untreated cells and
      at diminishing rates thereafter. The beta group, also containing minor structural
      and nonstructural polypeptides, was synthesized at highest rates from 5 to 7 h
      and at decreasing rates thereafter. The gamma group containing major structural
      polypeptides was synthesized at increasing rates until at least 12 h
      postinfection. (ii) The synthesis of alpha polypeptides did not require prior
      infected cell protein synthesis. In contrast, the synthesis of beta polypeptides
      required both prior alpha polypeptide synthesis as well as new RNA synthesis,
      since the addition of actinomycin D immediately after removal of cycloheximide
      precluded beta polypeptide synthesis. The function supplied by the alpha
      polypeptides was stable since interruption of protein synthesis after alpha
      polypeptide synthesis began and before beta polypeptides were made did not
      prevent the immediate synthesis of beta polypeptides once the drug was withdrawn.
      The requirement of gamma polypeptide synthesis for prior synthesis of beta
      polypeptides seemed to be similar to that of beta polypeptides for prior
      synthesis of the alpha group. (iii) The rates of synthesis of alpha polypeptides
      were highest immediately after removal of cycloheximide and declined thereafter
      concomitant with the initiation of beta polypeptide synthesis; this decline in
      alpha polypeptide synthesis was less rapid in the presence of actinomycin D which
      prevented the appearance of beta and gamma polypeptides. The decrease in rates of
      synthesis of beta polypeptides normally occurring after 7 h postinfection was
      also less rapid in the presence of actinomycin D than in its absence, whereas
      ongoing synthesis of gamma polypeptides at this time was rapidly reduced by
      actinomycin D. (iv) Inhibitors of DNA synthesis (cytosine arabinoside or
      hydroxyurea) did not prevent the synthesis of alpha, beta, or gamma polypeptides,
      but did reduce the amounts of gamma polypeptides made.

PMID- 4365322
TI  - Self-annealing of Sendai virus RNA.
AB  - Both complementary strands are found in 50S Sendai virion RNA. 50S Sendai virion
      RNA has been shown to consist of unequal amounts of a single population of plus
      and minus strands by annealing studies.

PMID- 4365323
TI  - Detection of baboon type C viral sequences in various primate tissues by
      molecular hybridization.
AB  - Nucleic acid sequences homologous to a single-stranded [(3)H]DNA transcript
      prepared from a baboon type C virus replicating in dog thymus cells can be
      readily detected in the cellular DNA of several Old World monkeys (baboon, patas,
      African green, and two species of macaques-rhesus and stumptail). These results
      demonstrate that primates other than the baboon also contain endogenous type C
      viral genes. With the hybridization conditions employed (S(1) nuclease, 65 C), no
      homologous sequences were detected in DNA from human or New World monkey tissues.
      Of various nonprimate tissues examined, only domestic cat cellular DNA was
      partially homologous to the baboon virus [(3)H]DNA transcript. In reciprocal
      experiments, [(3)H]DNA transcripts of RNAs from endogenous cat viruses (RD
      114/CCC group) show a significant partial homology with cellular DNA from Old
      World primates (baboon, patas, and rhesus monkey). The partial homology between
      type-C-related information in the DNA of domestic cats and various Old World
      monkeys suggests the possibility of horizontal transmission between the
      progenitors of these animals at some point in evolution. No nucleic acid
      sequences homologous to [(3)H]DNA transcripts prepared from type C viruses
      isolated from tumor tissue of a woolly monkey and a gibbon ape could be detected
      in any primate tissue DNA examined; however, a partial nucleic acid homology was
      found between woolly monkey and gibbon ape type C viral [(3)H]DNA and normal
      mouse cellular DNA.

PMID- 4365324
TI  - Specific fragmentation of DNA of adenovirus serotypes 3, 5, 7, and 12, and adeno
      simian virus 40 hybrid virus Ad2+ND1 by restriction endonuclease R.EcoRI.
AB  - The products of complete digestion of duplex DNA of each of seven human
      adenoviruses with restriction endonuclease R. EcoRI ranged from two fragments for
      adenovirus 7 DNA (Ad7) to six fragments for Ad12 and Ad2 DNA. Viral serotypes
      from the same subgroups appeared to have related cleavage sites; Ad3 DNA and Ad7
      (cl E46-LL) DNA were each cleaved into three fragments, and Ad7 (cl 19) DNA
      lacked one of the cleavage sites present in Ad3 and Ad7 (cl E46-LL) DNA. One of
      the cleavage sites in Ad2 DNA was deleted in the DNA' of adeno-SV40 hybrid virus
      Ad2(+)ND1, and three of the cleavage sites in Ad2 DNA were missing in Ad5 DNA.
      Thus, Ad2(+)ND1 DNA was cleaved into five and Ad5 DNA into three fragments. Each
      fragment represented a unique segment of viral DNA since each fragment was
      obtained in equimolar amounts and since the sum of the molecular weights of the
      fragments equaled the molecular weight of the homologous intact adenovirus DNA.

PMID- 4365325
TI  - Isolation and partial characterization of bacteriophage T5 mutants deficient in
      the ability to induce deoxynucleoside monophosphate kinase.
AB  - Two mutants of bacteriophage T5 deficient in the ability to induce wild-type
      levels of deoxynucleoside monophosphate kinase were isolated and partially
      characterized. Both mutations were demonstrated to be in a structural gene for
      the kinase. One of the mutants, designated dnk 10, induces no detectable levels
      of dCMP, dGMP, or dTMP kinase activity. Because the mutant can successfully
      infect nonpermissive cells, phage-induced deoxynucleoside monophosphate kinase
      appears to be an unessential function for phage production. DNA synthesis in dnk
      10-infected cells, however, is reduced to 30% of that observed in wild-type
      infected cells; phage production is reduced by a comparable amount. The dnk
      mutation has been mapped and located on the "C" region of the T5 genetic map, 6.3
      map units from the C1 locus.

PMID- 4365326
TI  - Mechanism of Sindbis virus-induced intrinsic interference with vesicular
      stomatitis virus replication.
AB  - Heterologous viral interference is induced by Sindbis virus against vesicular
      stomatitis virus (VSV) in a manner analogous to intrinsic interference with
      Newcastle disease virus replication. Interference in both systems (i) depends
      upon early expression of the inducing virus genome, (ii) shows similar kinetics
      of induction, (iii) does not involve interferon action, and (iv) appears to be
      manifest as an all-or-none effect. VSV can be added to the list of viruses
      blocked by intrinsic interference. Sindbis virus-induced intrinsic interference
      with VSV replication is not mediated through homotypic interference by defective
      interfering particles; rather, T-particle and B-particle synthesis is inhibited.
      Significantly, intrinsic interference has no effect on primary transcription
      directed by the virion-associated transcriptase in VSV-challenged cells. However,
      Sindbis virus appears to induce interference with the VSV-RNA synthesized
      subsequent to primary transcription, namely, that which is dependent on protein
      synthesis. Thus, the target of intrinsic interference appears to be a reaction
      subsequent to primary transcription but prior to the appearance of protein
      synthesis-dependent VSV RNA, secondary transcription.

PMID- 4365327
TI  - Reconstitution of infectivity and transcriptase activity of homologous and
      heterologous viruses: vesicular stomatitis (Indiana serotype), Chandipura,
      vesicular stomatitis (New Jersey serotype), and Cocal viruses.
AB  - RNA TRANSCRIPTASE ACTIVITIES HAVE BEEN RECONSTITUTED FROM FRACTIONATED COMPONENTS
      OF FOUR RHABDOVIRUSES: vesicular stomatitis virus (VSV) (Indiana serotype),
      Cocal, VSV (New Jersey), and Chandipura viruses. Heterologous reconstitution of
      transcription has been observed between template and enzyme fractions of VSV
      Indiana and Cocal viruses but not to any significant extent between components of
      the other two viruses with VSV Indiana template or enzyme. Homologous
      reconstitution of infectivity has been obtained for each virus from their
      respective parts as well as heterologous reconstitution between Cocal and VSV
      Indiana components.

PMID- 4365328
TI  - Phosphate acceptor amino acid residues in structural proteins of rhabdoviruses.
AB  - Partial acid hydrolysates of the [(32)P]phosphate- or [(3)H]serine-labeled
      proteins of purified vesicular stomatitis, rabies, Lagos bat, Mokola, or spring
      viremia of carp virions and of purified intracellular nucleocapsids of these
      viruses have been analyzed by paper electrophoresis for the presence of
      phosphorylated amino acids. Both phosphoserine and phosphothreonine, with the
      former predominant, were present in virion and nucleocapsid preparations that
      contained phosphoproteins. An exception was the fish rhabdovirus, which contained
      only phosphoserine. When vesicular stomatitis or rabies virus proteins were
      phosphorylated in a cell-free system by the virion-associated protein kinase and
      analyzed for the presence of phosphorylated amino acid residues, phosphoserine
      was again found to be more abundant than phosphothreonine. After in vitro protein
      phosphorylation, another phospho-compound, possibly a third phosphoamino acid,
      was detected in the partial acid hydrolysates of these viruses.

PMID- 4365329
TI  - Structure and molecular length of the large subunits of RD-114 viral RNA.
AB  - By electron microscopy, the large subunits of RD-114 RNA have a molecular weight
      of 5.0 x 10(6); they all have a characteristic secondary structure feature close
      to the middle.

PMID- 4365330
TI  - Host cell regulation of induction of Epstein-Barr virus.
AB  - When Epstein-Barr virus (EBV) negative cells (Raji) were treated with
      iododeoxyuridine, only the early antigen (EA) component was induced. There was no
      significant increase in EBV DNA and no virus particles were observed. Somatic
      cell hybrids were prepared from the fusion of Raji and D98 cells (D98/Raji). When
      these cells were treated with iododeoxyuridine, early antigen EBV DNA, and virus
      particles were synthesized. These data suggest cellular control over the
      expression of the EBV genome.

PMID- 4365331
TI  - Simple, quantitative assay for both xenotropic murine leukemia and ecotropic
      feline leukemia viruses.
AB  - A cat cell line carrying the genome of a murine sarcoma virus developed discrete
      foci in linear response to infection with feline leukemia virus or xenotropic
      murine C-type virus.

PMID- 4365332
TI  - [Tumors of skin appendages in West African Blacks].

PMID- 4365333
TI  - [Radioimmunoassay of urinary insulin using the method of separation by magnesium
      silicate. Application to the measure of insulin urinary clearance].

PMID- 4365334
TI  - The effects of noise level and elevated ambient temperatures upon selected
      reproductive traits in female Swiss-Webster mice.

PMID- 4365335
TI  - Isospora callimico n sp, (Coccidia: Eimeriidae) from Goeldi's marmoset (Callimico
      goeldii).

PMID- 4365336
TI  - Effect of open and closed formula rations on the performance of three strains of
      laboratory mice.

PMID- 4365337
TI  - A semisynthetic diet for long-term maintenance of hamsters to study effects of
      dietary vitamin A.

PMID- 4365338
TI  - The erythrocyte life span in the American opossum (Didelphis marsupialis
      Virginiana).

PMID- 4365339
TI  - Use of ventriculo-cisternal perfusion in conscious sheep.

PMID- 4365340
TI  - The parasitic ecology of the rodent mite Myobia musculi. I. Grooming factors.

PMID- 4365341
TI  - A feeder for controlling food consumption in treatment-control pairs of mice.

PMID- 4365342
TI  - Cranial hyperostosis of squirrel monkeys (Saimiri sciureus).

PMID- 4365343
TI  - Malignant melanoma in a black gerbil (Meriones unguiculatus).

PMID- 4365344
TI  - Blood chemistry of the rat kangaroo, Potorous tridactylus.

PMID- 4365345
TI  - Letter: Duodenal ulcer formation in the rat.

PMID- 4365346
TI  - Letter: Time of fertility as reflected by urinary protein levels.

PMID- 4365347
TI  - The biogenesis of mitochondria during proliferation and muturation of the
      intestinal epithelium of the rat. Effects of oxytetracycline.

PMID- 4365348
TI  - [An infant with 2 extraordinary intrauterine acquired infections].

PMID- 4365349
TI  - [Cestode parasites of small mammals (rodents and insectivora) of the Ivory Coast
      and Upper Volta].

PMID- 4365350
TI  - [Hypercalcemia and cancer].

PMID- 4365351
TI  - [Determination AND ANTIBODY PROPERTIES OF THE DUODENAL SECRETION IMMUNOGLOBULINS
      In celiac disease].

PMID- 4365352
TI  - A new and fast method of preparation of CEA.

PMID- 4365353
TI  - In vitro study on the effects of bradykinin potentiating factor and angiotensin
      II analogue on degradation and conversion of angiotensin I and II in plasma.

PMID- 4365354
TI  - [Problems of hospitalization and after-care planning. Apropos of a study on the
      length of stay in 9 Belgian psychiatric institutions].

PMID- 4365355
TI  - [Method of institutional analysis applicable to foster home therapy].

PMID- 4365356
TI  - [Intraoperative injuries of the carotid arteries and their surgical correction].

PMID- 4365357
TI  - [Effect of linuron and chlortoluron in short-term chronic experiment on young
      rats on the hexobarbital metabolism and activity of some liver enzymes].

PMID- 4365358
TI  - Selected topics in immunology: infectious mononucleosis and Australia antigen.

PMID- 4365359
TI  - Injection of foreign substances into single cells by cell fusion.

PMID- 4365360
TI  - Are there differences in contact inhibition of movement between normal and
      malignant cells.

PMID- 4365361
TI  - Evidence that mitogenic lectins induce changes in lymphocyte membrane fluidity.

PMID- 4365362
TI  - Neurotrophic control of colchicine effects on muscle?

PMID- 4365363
TI  - The neuropharmacology of aggression: a critical review.

PMID- 4365364
TI  - Syndrome of accelerated skeletal maturation in infancy, peculiar facies, and
      multiple congenital anomalies.

PMID- 4365365
TI  - Temperature-dependent expression of transformation by cold-sensitive mutant of
      murine sarcoma virus.
AB  - Morphological transformation of normal rat kidney cells by a murine sarcoma virus
      was found to be cold-sensitive. Cells transformed by the virus expressed their
      transformed phenotype at the permissive temperature (39 degrees ) but not at the
      nonpermissive temperature (33 degrees ), as judged by the criteria of
      morphological changes and colony-forming ability on monolayers of normal rat
      kidney cells. Cold-sensitive expression of transformation was specific for focus
      derived normal rat kidney cells transformed by the virus, readily reversible, and
      not lost during serial propagation of the cells. The genome of the murine sarcoma
      virus can be rescued by superinfection with Moloney leukemia virus at the
      permissive or nonpermissive temperature, and the rescued virus exhibited the same
      cold-sensitive properties as the original transforming virus. These results
      suggest that maintenance of the transformed state is continuously dependent on a
      cold-sensitive viral function.

PMID- 4365366
TI  - Identification of the chloramphenicol-binding protein in Escherichia coli
      ribosomes by partial reconstitution.
AB  - 50S-derived cores were prepared by treatment of 50S subunits with 0.4 M Licl
      (0.4c core) and 0.8 M Licl (0.8c core), respectively. 0.4c cores bind
      chloramphenicol whereas 0.8c cores do not. The split proteins obtained during the
      transitions 0.4c --> 0.8c were separated by DEAE-cellulose chromatography and
      Sephadex G-100 gel filtration. Reconstitution experiments with the fractionated
      proteins demonstrated that protein L16 is involved in chloramphenicol binding. In
      contrast to chloramphenicol, the CACCA-(N-acetyl-leucyl) fragment is bound by the
      0.8c core, i.e., this core contains the intact p-site moiety of the
      peptidyltransferase center. Puromycin can inhibit chloramphenicol binding
      completely. In the concentration range tested (up to 20 mM) the trinucleotide CCA
      inhibits chloramphenicol binding as effectively as puromycin, whereas an
      aminoacid mixture shows no inhibition. It is concluded that chloramphenicol acts
      exclusively on the a-site part of the peptidyltransferase center interfering with
      the binding of the last two or three nucleotides (3' end) of aminoacyl-tRNA.

PMID- 4365367
TI  - The synthesis and enzymatic polymerization of nucleotides containing mercury:
      potential tools for nucleic acid sequencing and structural analysis.
AB  - A simple acetoxymercuration reaction for introducing covalently bound mercury
      atoms into nucleotides is described. The 5-mercuriacetate derivatives of UTP,
      CTP, dUTP, and dCTP, as well as the 7-mercuriacetate derivative of 7-deazaATP,
      have been prepared by this procedure and tested as substrates for nucleic acid
      polymerases. These nucleotides, in the absence of added mercaptan, are not
      polymerized and in most instances are potent enzyme inhibitors. However,
      conversion of these mercuriacetates to mercurithio compounds in situ by the
      addition of one of various mercaptans, yields nucleoside triphosphates that are
      excellent substrates for all polymerases tested: Escherichia coli and T7 RNA
      polymerases, DNA polymerase I of E. coli, DNA polymerase of avian myeloblastosis
      virus, and calf-thymus terminal deoxynucleotidyl transferase. By varying the
      mercaptan used to promote syntheses it is possible to access certain structural
      limitations in the enzyme's nucleoside triphosphate binding site. These
      mercurinucleotides appear to have a diversity of potential applications: (1) as
      heavy-atom reagents for crystallographic and microscopic studies; (2) as affinity
      probes for enzymes sensitive to sulfhydryl modification; (3) as steric probes of
      substrate-binding sites on enzymes; and (4) as reagents for forming covalent
      protein-polynucleotide complexes.

PMID- 4365368
TI  - Biological activity of 1alpha-hydroxycholecalciferol, a synthetic analog of the
      hormonal form of vitamin D3.
AB  - 1,25-Dihydroxycholecalciferol, the apparent active hormonal form of
      cholecalciferol (vitamin D(2)), is formed from cholecalciferol by specific and
      sequential hydroxylations of the sterol at carbons 25 and 1. Recently, 1alpha
      hydroxycholecalciferol was synthesized and we report on its biological activity
      in rachitic chicks. 1alpha-Hydroxycholecalciferol is identical in potency to 1,25
      dihydroxycholecalciferol in stimulation of intestinal calcium absorption; either
      sterol elicits a near maximal effect at a dose of 0.3-0.6 nmol. The time-course
      of action of 1alpha-hydroxycholecalciferol also parallels that of the active
      metabolite 1,25-dihydroxycholecalciferol with a maximal increase in calcium
      transport occurring 5-10 hr after administration of sterol to vitamin D-deficient
      chicks. 6.5 nmol of 1alpha-hydroxycholecalciferol causes a doubling in calcium
      absorption in only 2-3 hr, which is the most rapid physiologic response yet
      detected for a vitamin D-sterol. 1alpha-Hydroxycholecalciferol is active also in
      enhancing bone calcium resorption and, like 1,25-dihydroxycholecalciferol, is at
      least 10 times as active as cholecalciferol in mobilizing bone calcium and
      raising plasma calcium concentration. It is concluded that 1alpha
      hydroxycholecalciferol represents a synthetic analog of 1,25
      dihydroxycholecalciferol that can be used both to study the mechanism of action
      of this hormone and as a therapeutic agent in the treatment of patients with
      certain metabolic bone diseases.

PMID- 4365369
TI  - Lateral phase separations in membrane lipids and the mechanism of sugar transport
      in Escherichia coli.
AB  - Changes in slope of Arrhenius plots for transport can, in some instances, be
      detected at two different temperatures for cells that have a relatively simple
      fatty-acid composition in the membrane lipids. These characteristic temperatures
      correlate with the characteristic temperatures that define changes of state in
      membrane phospholipids as revealed by the paramagnetic resonance of the spin
      label TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl). The higher of these
      characteristic temperatures is that at which the formation of solid patches of
      membrane lipids is first detected. The lower is the end point of the course of
      lateral phase separations, at which all the membrane lipids are in a solid phase.
      For cells enriched for elaidic acid, the rate of transport increase by as much as
      2-fold as the temperature is decreased by less than 1 degrees , at the higher
      characteristic temperature. At this characteristic temperature, lateral phase
      separations begin in the membrane phospholipids. This is also the temperature
      where one predicts a striking increase in the lateral compressibility of the
      membrane lipids. These data are thus interpreted to indicate that a component of
      the transport system vertically penetrates one or both monolayer faces of the
      membrane during transport, or that some other event involving the lateral
      compression of the phospholipids is important for transport.

PMID- 4365370
TI  - Induction of the stellate configuration in cultured iris epithelial cells by
      adenosine and compounds related to adenosine 3':5'-cyclic monophosphate.
AB  - Adenosine, dibutyryl cyclic AMP, monobutyryl cyclic AMP, cyclic AMP, and 5'-AMP
      have a remarkable morphogenetic effect on cultured iris epithelial cells obtained
      from adult newt. They alter the broad undulating membrane of the cell into
      branching strands of cytoplasm, a configuration that has been named "stellate."
      Theophylline, a phosphodiesterase inhibitor also induces the stellate
      configuration. This transient morphological alteration is detectable by 30 min
      and becomes maximal 80 min after treatment. In the continued presence of the
      effective compounds the altered cells return to their normal shape, although the
      recovery period is variable. The morphological alteration of iris epithelial
      cells in vitro observed in the present experiment is reminiscent of that which
      occurs during the dedifferentiation phase in lens regeneration in vivo. These
      observations suggest that induction of the stellate configuration is relevant to
      the mechanism of dedifferentiation of newt iris epithelial cells during Wolffian
      lens regeneration.

PMID- 4365371
TI  - Enumeration of activated thymus-derived lymphocytes by the virus plaque assay.
AB  - Lymphocytes activated by antigens or mitogens acquire the capacity to replicate
      viruses, and the number of activated lymphocytes can be estimated by the virus
      plaque assay. Concanavalin A and pokeweed mitogen produced 33-fold and 17-fold
      increases in virus plaqueforming cells (V-PFC), respectively, above background,
      while lipopolysaccharide produced only a 2- to 3-fold increase. T (thymus-derived
      lymphocyte)-depleted lymphocyte populations, derived from anti-theta-treated or
      nude (arthymic) mouse spleens, failed to produce V-PFC after culture with
      concanavalin A or pokeweed mitogen. The present studies thus demonstrate that the
      virus plaque assay measures activated T-lymphocytes.A dissociation between the V
      PFC response and cell proliferation was previously observed in antigen-stimulated
      cells cultured in the presence of mitotic inhibitors. In the present studies,
      while stimulation of CBA (H2(k)) lymphocytes by DBA/2 (H2(d)) cells produced high
      levels of thymidine incorporation, lymphocyte target-cell cytotoxicity, and V
      PFC, stimulation of BALB/c (H2(d)) lymphocytes against DBA/2 (H2(d)) cells
      resulted in even higher levels of thymidine incorporation with a virtual absence
      of cytotoxic lymphocytes or V-PFC. These results indicate that proliferation is
      not a sufficient condition for permitting lymphocytes either to exert
      cytotoxicity on target cells or to replicate viruses, and suggest that there may
      be a correlation between the development of V-PFC and cytotoxic lymphocytes. They
      are consistent with the view that there are at least two functional
      subpopulations of T-lymphocytes.

PMID- 4365372
TI  - In vitro transcription of simian virus 40 sequences in SV3T3 chromatin.
AB  - The template properties of chromatin were studied in a system in which
      transcription of unique genes could be examined. Chromation and DNA were isolated
      from SV3T3 cells, a line of simian virus 40 (SV40)-transformed mouse cells, and
      used as templates for Escherichia coli RNA polymerase. The SV40 sequences in the
      RNA transcribed in vitro and in RNA isolated from the transformed cells were
      analyzed by hybridization to radioactive RNA transcribed from SV40 DNA. The
      results indicate that the same sequences of the SV40 "-" strand (DNA strand which
      serves as a template for early RNA) are transcribed in vitro from chromatin as
      are found in transformed cells. In contrast, when the DNA isolated from SV3T3
      chromatin by removal of proteins is used as a template, the entire SV40 "-"
      strand is transcribed. It is concluded that the specific template restriction
      observed with chromatin is due to the presence of proteins associated with the
      DNA.

PMID- 4365373
TI  - Adhesion of cultured fibroblasts to insoluble analogues of cell-surface
      carbohydrates.
AB  - Animal cells are coated with complex carbohydrates. Insoluble analogues of these
      substances were prepared by coupling monosaccharides to Sephadex beads
      (crosslinked dextran), and the interactions between these derivatives and three
      established cell lines were studied. A virally transformed fibroblast, simian
      virus 40-transformed 3T3 cells, adhered to the beads derivatized with D
      galactose, but did not adhere to the corresponding beads derivatized with D
      glucose or N-acetyl-D-glucosamine. Cells that adhered to the galactose-beads
      appeared to initiate a nucleation process in that they became more adhesive
      towards the cells in suspension, leading to the formation of large aggregates
      containing both cells and galactose-beads. The results suggest that specific
      carbohydrates are involved in the processes of cell recognition or cell adhesion,
      or both.

PMID- 4365374
TI  - Antiviral effect of interferon covalently bound to sepharose.
AB  - Interferon, covalently bound to Sepharose 4B activated by cyanogen bromide,
      induces the antiviral state in sensitive cells. The antiviral effect is
      neutralized by antiserum specific to interferon and is recovered thereafter when
      the antibody is detached from the interferon by treatment at low pH. Binding
      interferon to Sepharose increases the stability of the molecule. It is likely
      that the interferon molecule acts on the cell receptor without being detached
      from the beads. However, the data do not exclude the possibility of a small loss
      of interferon, or fragments of it, after contact with the cell.

PMID- 4365375
TI  - A cell-contact model for cellular position determination in development.
AB  - The fate of a cell in a developing organism is a function of its position within
      the organism. The molecular mechanism that cells use to determine their position
      and to convert positional information into a form that can be used to regulate
      the expression of genes is not understood. This paper presents a model in which
      contacts between complementary molecules on plasma membranes of adjacent cells
      regulate the concentration of a morphogenetic substance and transmit positional
      information. This model is described by four equations that, when solved with
      realistic parameters, demonstrated that this mechanism will produce discrete
      populations of cells within a few hours from an initially undifferentiated array
      of cells. The model suggests an explanation for several phenomena that have been
      observed and suggests experiments to test it and to clearly differentiate it from
      other models for position determination.

PMID- 4365376
TI  - NAD(P) glycohydrolase deficiency in human erythrocytes and alteration of cytosol
      NADH-methemoglobin diaphorase by membrane NAD-glycohydrolase activity.
AB  - Erythrocytic NADH methemoglobin diaphorase acquires NADH-dichlorophenolindophenol
      diaphorase activity when enzyme-associated NAD is removed. This transformation is
      reversible and can be mediated by membrane NAD glycohydrolase (EC 3.2.2.5) in
      hemolysates as well as in intact cells exposed to hydrogen peroxide. It is
      abolished either in NADH methemoglobin diaphorase deficiency or in NAD(P)
      glycohydrolase (EC 3.2.2.6) deficiency which is common in Afro-American but not
      in European-American adults. Activities of erythrocytic NADP glycohydrolase and
      NAD glycohydrolase appear to depend on a single membrane enzyme.

PMID- 4365377
TI  - Supersensitivity and subsensitivity of the beta-adrenergic receptor in pineal
      gland regulated by catecholamine transmitter.
AB  - Depletion of neural norepinephrine by reserpine treatment or by denervation
      resulted in a greater induction of serotonin N-acetyltransferase (EC 2.3.1.5) and
      a higher elevation of cyclic AMP in postsynaptic pineal cell to small amount of
      isoproterenol. This increase in responsiveness occurs rapidly within 24 hr after
      treatment with reserpine. Repeated administration of isoproterenol to the
      denervated or reserpine-treated rats not only suppressed the superinduction, but
      also caused a decreased response to isoproterenol in cultured pineal cells.
      Cultured pineal cells from denervated or reserpine-treated rats were about 10
      times more responsive to small amounts of isoproterenol. The response of cultured
      pineal cells of rats which were repeatedly injected with isoproterenol was
      markedly reduced after exposure to submaximal amounts of catecholamines. The
      maximal increase in N-acetyltransferase was the same in denervated, reserpine
      treated, isoproterenol-treated, and untreated pineal cells. Exposure of rats to
      continuous lighting (a procedure that reduces sympathetic nerve activity)
      resulted in a superinduction of pineal N-acetyltransferase by isoproterenol.
      These observations indicate that the responsiveness of the postsynaptic beta
      adrenergic receptor is conditioned by prior exposure to its agonist,
      norepinephrine. Decreased norepinephrine results in supersensitivity, and
      repeated exposure to large amounts of catecholamines causes subsensitivity
      (tolerance).

PMID- 4365378
TI  - The synthesis in vitro of RNA polymerase subunits of Escherichia coli.
AB  - DNA from transducing bacteriophage that carry the structural gene for the beta
      subunit of RNA polymerase has been used to direct protein synthesis in a cell
      free transcription-translation system. A polypeptide species has been detected
      which appears to be beta-subunit material made in vitro.

PMID- 4365379
TI  - Structure of liver alcohol dehydrogenase at 2.9-angstrom resolution.
AB  - The conformation of the polypeptide chain in horse liver alcohol dehydrogenase
      (EC 1.1.1.1), as well as the binding sites for some inhibitor molecules, have
      been determined from x-ray crystallographic data to a resolution of 2.9 A. Each
      subunit of the dimeric molecule is organized into two parts unequal in size and
      separated by a wide and deep active-site cleft. The adenosine moiety of the
      coenzyme is bound within the smaller region. Interactions between these coenzyme
      binding substructures define the subunit contact area of the molecule. The
      "catalytic" zinc atoms are bound at the bottom of the clefts about 20 A from the
      surface of the molecule. The coenzyme binding region has a main-chain
      conformation very similar to a corresponding region in lactate and malate
      dehydrogenase. It is suggested that this substructure is a general one for
      binding of nucleotides and, in particular, the coenzyme NAD(+).

PMID- 4365380
TI  - Mechanism of action of nerve growth factor and cyclic AMP on neurite outgrowth in
      embryonic chick sensory ganglia: demonstration of independent pathways of
      stimulation.
AB  - The suggested role of adenosine 3':5'-cyclic monophosphate as the "second
      messenger" in the neurite outgrowth from chick embryonic sensory ganglia mediated
      by nerve growth factor was examined. Although N(6),O(2)-dibutyryl adenosine 3':5'
      cyclic monophosphate induces fiber outgrowth at concentrations of 1-5 mM, this
      response is morphologically distinct from that produced by nerve growth factor,
      is pH dependent, is mimicked by sodium butyrate, and does not occur in
      sympathetic ganglia. In addition, nerve growth factor does not alter the amounts
      of intracellular cyclic AMP during incubations up to 24 hr and does not stimulate
      adenylate cyclase in broken-cell preparations. Addition of theophylline, an
      inhibitor of phosphodiesterase, causes increases in intracellular levels of
      cyclic AMP but does not affect fiber outgrowth. These observations indicate that
      the nerve growth factor response is not mediated through cyclic AMp and that
      stimulation of sensory ganglia by exogenous cyclic AMP derivatives is probably of
      limited physiological significance. These findings are also compatible with the
      developing hypothesis, based on structural similarities, that nerve growth factor
      and insulin exert their effects on their respective responsive tissues by related
      mechanisms.

PMID- 4365381
TI  - Growth inhibition and morphological changes caused by lipophilic acids in
      mammalian cells.
AB  - Human (HeLa, Chang liver, L-132, and Intestine 407) and other mammalian (XC,
      SV3T3, and chick-embryo) cells in tissue culture are at least as sensitive to
      inhibition by lipophilic acids and nitrite as bacteria. Some of these compounds
      are the most frequently used antimicrobial food additives. Short-chain fatty
      acids (up to hexanoate) and parabens induce, at partially inhibitory
      concentrations, a jagged cell shape in continuous epithelial-like cell lines,
      such as HeLa, Chang liver, L-132, and Intestine 407. This morphological effect is
      not mediated or enhanced by butyryl cyclic AMP, which specifically affects
      fibroblasts.

PMID- 4365382
TI  - Presynaptic inhibition at inhibitory nerve terminals.  A new synapse in the
      crayfish stretch receptor.
AB  - Previous physiological evidence has shown that the receptor neuron of the slowly
      adapting stretch receptor organ of crayfish receives synapses from three
      inhibitory axons, while the receptor muscle is innervated by both excitatory and
      inhibitory axons. Fine structural studies have indicated that after certain
      preparative procedures synaptic vesicles in the inhibitory terminals on dendrites
      of the receptor neuron appear small and elongate, while those in the excitatory
      terminals on the receptor muscle are round and larger. This study describes a new
      synapse between two inhibitory nerve endings on the receptor neuron. One axon,
      containing small elongate vesicles, forms a presynaptic chemical contact with
      another morphologically similar axon that, itself, presumably releases inhibitory
      transmitter onto the receptor neuron. A second type of presynaptic axo-axonic
      synapse, analogous to one previously described in another crustacean muscle, was
      also found between presumed inhibitory and excitatory nerve terminals on the
      receptor muscle. Thus, the stretch receptor has a relatively complex organization
      with a morphological basis for two types of presynaptic inhibition: one on
      excitatory terminals and the other on inhibitory terminals.

PMID- 4365383
TI  - Regulation of 25-hydroxycholecalciferol metabolism by inorganic phosphate.

PMID- 4365384
TI  - Malignancy of the uterine corpus following irradiation therapy for squamous cell
      carcinoma of the cervix.

PMID- 4365385
TI  - Studies on a specific glucocorticoid-hormone receptor in the developing chick
      retina.

PMID- 4365386
TI  - Karyometry in the estimation of nuclear population in pulmonary carcinomas.

PMID- 4365387
TI  - Ultrastructure of human mesotheliomas.

PMID- 4365388
TI  - Titrations of various mouse mammary tumor viruses in different mouse strains.

PMID- 4365389
TI  - Mechanism of resistance to mammary tumor development in C57BL and I strains of
      mice. II. Inherent differences between the two strains.

PMID- 4365390
TI  - C-type particles in baboon (Papio cynocephalus) preimplantation embryos.

PMID- 4365391
TI  - Inhibitory effect of 2-br-alpha-ergocryptine-methane-sulfonate on renal
      carcinogenesis in the male hamster.

PMID- 4365392
TI  - Proceedings: Experimental observations on intestinal healing in malignant
      disease.

PMID- 4365393
TI  - Letter: Doxapram hydrochloride.

PMID- 4365394
TI  - Editorial: Problems in receptor identification: catecholamines.

PMID- 4365395
TI  - Letter: Eosinophilia in bronchogenic carcinoma.

PMID- 4365396
TI  - Nerve conduction velocity in patients on long-term diphenylhydantoin therapy.

PMID- 4365397
TI  - Uptake of the neurotransmitter candidate glutamate by glia.

PMID- 4365398
TI  - 1,25-dihydroxyvitamin D3: a kidney-produced steroid hormone essential to calcium
      homeostasis.

PMID- 4365399
TI  - Effect of Sendai virus on the respiration of rabbit spermatozoa.

PMID- 4365400
TI  - Editorial: Islet cell tumours of the pancreas.

PMID- 4365401
TI  - Cation dependence of high-affinity angiotensin II binding to adrenal cortex
      receptors.
AB  - The specific binding of monoiodinated angiotensin II by particulate receptors
      from the bovine adrenal cortex is enhanced by addition of sodium and potassium
      ions, but not other cations. In the presence of 140 millimolar sodium, increased
      uptake of angiotensin II by adrenal receptors is associated with the appearance
      of high-affinity binding sites with an association constant of 2 x 10(9) liters
      per mole.

PMID- 4365402
TI  - Incrementing responses in myasthenia gravis.

PMID- 4365403
TI  - The ubiquity of type-C viruses in spargana of Spirometra spp.

PMID- 4365404
TI  - Recovery following cranial nerve dysfunction and muscle weakness in infancy.

PMID- 4365405
TI  - Letter: Surgical correction of islet cell carcinoma in a dog.

PMID- 4365406
TI  - Regulation of aspartokinase activity in non-fermentative, marine eubacteria.

PMID- 4365407
TI  - NADH- and N2-oxidation in hydrogen bacteria studied by respiratory chain
      inhibitors.

PMID- 4365408
TI  - Comparison of 13C spin-lattice relaxation times in phospholipid vesicles and
      mutilayers.

PMID- 4365409
TI  - EPR studies on the mechanism of action of succinate dehydrogenase in activated
      preparations.

PMID- 4365410
TI  - Ultrastructural studies of periostracum formation in the hard shelled clam
      Mercenaria mercenaria (L).

PMID- 4365411
TI  - The rapid separation and isolation of mono- and oligonucleotides by high speed
      liquid chromatography: an ion exchange, reversed-phase system.

PMID- 4365412
TI  - Guanosine 3', 5'-cyclic monophosphate phosphodiesterase activity of Bacillus
      licheniformis.

PMID- 4365413
TI  - Resolution of two protein kinase modulators from lactating rat mammary gland.

PMID- 4365414
TI  - Acetylcholine causes a net decrease in phosphatidylinositol and a net increase in
      phosphatidic acid in mouse pancreas.

PMID- 4365415
TI  - Comparative studies on composition of liver phospholipids from rats fed oleic or
      elaidic acid.

PMID- 4365416
TI  - Evidence for a regulatory function related to the expression of the polyoma
      genome following the onset of virus DNA replication.

PMID- 4365417
TI  - Effect of X537A on the release of amino acids in retina.

PMID- 4365418
TI  - The nucleic acids of viruses.

PMID- 4365419
TI  - Cytomegaloviruses.

PMID- 4365420
TI  - Selective and reversible inhibition of initiation of protein synthesis in
      mammalian cells.

PMID- 4365421
TI  - Mating reaction in Saccharomyces cerevisiae. V. Changes in the fine structure
      during the mating reaction.

PMID- 4365422
TI  - Liver circulation.

PMID- 4365423
TI  - Role of silicon in diatom metabolism. V. Silicic acid transport and metabolism in
      the heterotrophic diatom Nitzschia alba.

PMID- 4365424
TI  - Electron microscope studies on spermiogenesis in various animal species.

PMID- 4365425
TI  - Comparative studies of the juxtaglomerular apparatus.

PMID- 4365426
TI  - Hepatography: distribution of the oily contrast medium after intrasplenic and
      intravenous (mesenteric) injection.

PMID- 4365427
TI  - Micronuclei in mouse bone-marrow cells. A simple in vivo model for the evaluation
      of drug-induced chromosomal aberrations.

PMID- 4365428
TI  - The uvrC  gene in Salmonella: phenotypic properties and a preliminary mapping.

PMID- 4365429
TI  - Herpes simplex.

PMID- 4365430
TI  - [Ultrastructure of the nucleus-associated body ("centriolar plaque", "MTOC",
      "KCE") during interphase in the conidia of Aspergillus nidulans].

PMID- 4365431
TI  - Paul-Bunnell-Davidsohn antibody of infectious mononucleosis and Epstein-Barr
      virus.

PMID- 4365432
TI  - [Differential diagnosis of benign pigmented skin tumors].

PMID- 4365433
TI  - Concurrence of multiple sclerosis and glioma.
AB  - Three cases are reported of concurrence of malignant gliomas (astrocytomas and
      glioblastomas) with multiple sclerosis (MS). This situation may lead to
      considerable diagnostic difficulties, yet an accurate appraisal is of prognostic,
      if not therapeutic, value. There is suggestive but inconclusive evidence that the
      two conditions may be causally related, malignant astrocytic tumours arising from
      plaques of MS. The small number of reported cases makes statistical analysis
      impossible, but the scanty literature may not reflect the true incidence.

PMID- 4365434
TI  - Reaction patterns of intimal mesenchyme to injury, and repair in atherosclerosis.

PMID- 4365435
TI  - Proliferation of arterial cells in atherosclerosis.

PMID- 4365436
TI  - Thrombosis and connective tissue interrelationships in arteriosclerosis.

PMID- 4365437
TI  - [Resection of the tracheal bifurcation with preservation of both lungs].

PMID- 4365438
TI  - Distribution of some possible intermediates of the haem biosynthesis.

PMID- 4365439
TI  - Androgen receptors in rat testis.

PMID- 4365440
TI  - Enzymes of glycerol metabolism in developing rat liver and kidney.

PMID- 4365441
TI  - Protein-prednisolone interaction in the regulation of the activity of some liver
      and kidney enzymes in growth-plateaued rats.

PMID- 4365442
TI  - Kinetics of the photo-induced EPR signal in whole-cell Rhodospirillum rubrum:
      effects of light intensity, dark adaptation, temperature, and microwave power.

PMID- 4365443
TI  - An ultrastructural study of silica deposition in the freshwater sponge Spongilla
      lacustris.

PMID- 4365444
TI  - Benign clear cell tumor of lung.

PMID- 4365445
TI  - Absence of adenine nucleotide release from autonomic ganglion.

PMID- 4365446
TI  - Editorial: Treatment of genital herpes.

PMID- 4365447
TI  - [Experience in using a zinc-corticotropin suspension in the therapy of certain
      dermatoses].

PMID- 4365448
TI  - Antioestrogens in treatment of breast cancer.

PMID- 4365449
TI  - The bacterial etiology of pneumatosis cystoides intestinalis.

PMID- 4365450
TI  - [Failure to produce renal changes in the guinea pig by chronic administration of
      silicic acid: an experiment concerning the etiology of Balkan nephropathy
      (author's transl)].

PMID- 4365451
TI  - The effects of acetylcholine and of synaptic stimulation on the sensorimotor
      cortex of cats. II. Comparison of the neuronal responses to reticular and other
      stimuli.

PMID- 4365452
TI  - [Effect of hydroxyurea and 5-fluorouracil on enzyme pattern and ultrastructure of
      liver, kidney, and pancreas in rats (author's transl)].

PMID- 4365453
TI  - p-Chlorophenylalanine treatment in developing rats: protein and lipids in whole
      brain and myelin.

PMID- 4365454
TI  - Amino acid release from isolated rat dorsal root ganglia.

PMID- 4365455
TI  - Effect of dorsal root section on amino acids of rat spinal cord.

PMID- 4365456
TI  - Effects from the somatic sensory cortex on transmission through the spinocervical
      tract.

PMID- 4365457
TI  - Comparison of purified lactate dehydrogenases from normal rat liver and Morris
      hepatomas in rats and in culture.

PMID- 4365458
TI  - Microglia and reactive "M" cells of degenerating central nervous system: does
      similar morphology and function imply a common origin?

PMID- 4365459
TI  - The effect of slow freezing and hypertonic NaCl on the hydrolytic activity of rat
      erythrocyte cyclic AMP phosphodiesterase and its sensitivity to the inhibitor,
      D,L-4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone.

PMID- 4365460
TI  - Further observations on urethral chromaffin cells: an electron microscopic study.

PMID- 4365461
TI  - Characteristics of murine C-type viruses. I. Independent assortment of
      infectivity in one in vivo and four in vitro assays.

PMID- 4365462
TI  - Study by the isotopic antiglobulin technique of a cross-reacting murine antibody
      produced by immunization with a syngeneic SV40 tumor.

PMID- 4365463
TI  - [5-ht-induced relaxation and cyclic AMP in a molluscan smooth muscle (author's
      transl)].

PMID- 4365464
TI  - The distribution of the sensory input in the dorsal spinal cord of the tortoise.

PMID- 4365465
TI  - Composition drift in the cytochrome c cistron.

PMID- 4365466
TI  - Effect of angiotensin II on blood volume and water intake in the rat.

PMID- 4365467
TI  - Induction and complementation of lysine auxotrophs in Saccharomyces.

PMID- 4365468
TI  - Interrelations between sulfate-reducing and methane-producing bacteria in bottom
      deposits of a fresh-water lake. II. Inhibition experiments.

PMID- 4365469
TI  - Cellular lipoproteins, calcium and magnesium in Novikoff hepatoma, liver of tumor
      bearing and liver of normal rats.

PMID- 4365470
TI  - [Use of 4-aminoazobenzene for studying the activity of the acetylating and
      succinylating systems].

PMID- 4365471
TI  - [Letter: Are anticonvulsive substances also mutagenic?].

PMID- 4365472
TI  - [Letter: 99mTc pyrophosphates in radioisotope brain scanning].

PMID- 4365473
TI  - [Letter: Identical malignant diseases in members of the same family].

PMID- 4365474
TI  - Streptozotocin treatment for malignant insulinoma.

PMID- 4365475
TI  - I-active antigen of human erythrocyte membrane.

PMID- 4365476
TI  - [Glucose-6-phosphate dehydrogenase isoenzymes in the liver and hepatomas of
      mice].

PMID- 4365477
TI  - Synthesis and morphogenetic activity of derivaties and analogs of aryl geranyl
      ether juvenoids.

PMID- 4365478
TI  - A microcolumn apparatus for rapid cleanup of 2,4-dinitrophenylmethylamine
      extracts for carbamate pesticide analysis.

PMID- 4365479
TI  - Chromatin-associated receptors for estrogen, progesterone, and
      dihydrotestosterone and the induction of egg white protein synthesis in chick
      magnum.

PMID- 4365481
TI  - Studies on experimental lymphoma induced by Herpesvirus saimiri in nonhuman
      primates. Introduction to the symposium.

PMID- 4365480
TI  - [State of tissue enzyme systems in the initial stages of phospholipid-glyceride
      biosynthesis during starvation and adrenaline stimulation].

PMID- 4365482
TI  - Oncogenic herpesviruses in species other than owl monkeys. A review.

PMID- 4365483
TI  - [Regeneration of Mesothelial, endothelial, and synovial cells].

PMID- 4365484
TI  - [Obesity as a disease: a wrong concept].

PMID- 4365485
TI  - [Pericardial agenesis. Apropos of a case].

PMID- 4365486
TI  - [Vaquez' disease masked by Biermer's anemia].

PMID- 4365487
TI  - A serological study on mentally ill patients with particular reference to the
      prevalence of herpes virus infections.

PMID- 4365488
TI  - The polypeptide composition of the encephalomyocarditis virus particle.

PMID- 4365489
TI  - Nuclear localization and covalent linkage of infective virus DNA to chromosomal
      DNA of non-producer Rous sarcoma cells.

PMID- 4365490
TI  - Inhibition of simian virus 40 DNA synthesis by frog virus 3.

PMID- 4365491
TI  - Inhibition of rhinovirus RNA synthesis in diploid cells by a substituted
      guanidine compound having a different mode of action from guanidine.

PMID- 4365493
TI  - [Role of NADH Hplus and ATP adenine amino groups in the reaction of reductive
      amination of alpha-ketoglutaric acid].

PMID- 4365492
TI  - [Oxidative phosphorylation in rat liver mitochondria under deep freeaing and
      thawing].

PMID- 4365494
TI  - [Cytological and ultrastructural study of a case of genital herpes during acute
      leukemia].

PMID- 4365495
TI  - [Dostoievski or the pleasure of suffering].

PMID- 4365496
TI  - [Geomicrobiological studies. XII. Behavior of microorganisms on uranium
      containing rocks].

PMID- 4365497
TI  - Alteration of fermentation products from butyrate to acetate by nitrate reduction
      in Clostridium perfringens.

PMID- 4365498
TI  - Sensitivity of mesenteric vascular bed to vasoconstrictor drugs during reactive
      hyperemia.

PMID- 4365499
TI  - Partially coated vacuoles--a new type of endocytotic structure.

PMID- 4365501
TI  - The mechanism of action of methionyl-tRNA synthetase from Escherichia coli.
      Mechanism of the amino-acid activation reaction catalyzed by the native and the
      trypsin-modified enzymes.

PMID- 4365502
TI  - Myocardial energy metabolism.

PMID- 4365503
TI  - Energy sources of cardiac contraction.

PMID- 4365500
TI  - [The lipotropins (author's transl)].

PMID- 4365504
TI  - Letter: 14-Sec and 6-sec spikes on sleep EEG as normal finding in stage REM.

PMID- 4365505
TI  - Effects of sodium acetate and sodium chloride on EMS-induced chlorophyll
      mutations in barley.

PMID- 4365506
TI  - Cyclic nucleotide phosphodiesterase of Chlamydomonas reinhardtii.

PMID- 4365507
TI  - Transformation of mouse cells infected with AKR leukemia virus by benzene extact
      fractions of city air particles.

PMID- 4365508
TI  - Biochemical reactions involved in pancreatic enzyme secretion. I. Activation of
      the adenylate cyclase complex.

PMID- 4365509
TI  - Comparison of dihydrotachysterol and 5,6-trans vitamin D3 on intestinal calcium
      absorption in patients with chronic renal failure.

PMID- 4365511
TI  - Proceedings: 67Ga citrate liver scanning: evaluation of its use in 80 patients
      and evidence of intrahepatic distribution by autoradiography.

PMID- 4365510
TI  - Collagen proline hydroxylase activity and 35S sulphate uptake in human liver
      biopsies.
AB  - In an effort to assess connective tissue biosynthetic activity in human liver
      disease, collagen proline hydroxylase (a key enzyme in collagen biosynthesis) and
      the uptake of (35)S sulphate (a precursor of sulphated mucopolysaccharides) were
      measured in hepatic tissue obtained mainly by percutaneous biopsy.A procedure is
      described for the quantitation of collagen proline hydroxylase in cryostat
      sections which allows for the simultaneous histopathological examination of the
      liver specimen. A three to eightfold increase in the activity of this enzyme was
      found in four cirrhotic livers compared with the mean value of four normal livers
      and two biopsies from patients with Gilbert's syndrome. Elevated hydroxylase
      levels were found also in five patients with hepatic dysfunction but without
      cirrhosis (four alcoholics and one patient with persistent hepatitis associated
      with serum smooth muscle antibody). It is suggested that the hepatic level of
      collagen proline hydroxylase may be a useful quantitative index of fibroblastic
      activity in human liver disease. Autoradiographic studies of radioactive sulphate
      uptake in biopsy specimens from patients with chronic liver disease showed an
      exaggerated incorporation of isotope not only at sites of established
      fibrogenesis but also in the walls of sinusoids throughout the liver.

PMID- 4365512
TI  - Proceedings: Primary liver cell carcinoma: alcohol and chronic liver disease.

PMID- 4365514
TI  - Mutants of nonproducer cell lines transformed by murine sarcoma virus. 3.
      Detection and characterization of RNA specific for helper and sarcoma viruses.
AB  - BALB/3T3 cells transformed by the Kirsten sarcoma virus (nonvirus producer
      BALB/3T3 cells) and mutant cell lines derived therefrom by treatment with
      bromodeoxyuridine (BrdU) were analyzed for expression of virus-specific RNA using
      single-stranded DNA transcripts of Rauscher leukemia virus (RLV), a virus
      activated in one of the cell lines (58-2T), and Ki-SV-specific DNA transcript;
      the latter transcript after removal of all sequences cross-reactive with RLV RNA.
      The Rauscher virus DNA detected multiple copies of viral RNA in virus-producing
      cells ( approximately 2.5 x 10(3)/cell) whether infected with RLV or activated to
      produce virus with BrdU. Nonproducer (NP) cells and normal BALB cells showed
      small numbers of RNA genomes (70-250/cell) and only partial saturation of the
      transcript. The intracellular RNA sedimented at 35S (main peak) with a variable
      minor peak at 20S with the exception of one mutant cell, M-43-2 (main peak at 26
      27S). The 58-2T transcript reacted preferentially in NP cells and their
      derivatives with biphasic kinetics suggesting the possibility of sequences
      specific for the original transforming virus. The size of Ki-SV specific
      sequences were 30S in mutant cells whether or not complete virus was being
      produced and independent of in vivo transplantability.

PMID- 4365513
TI  - Cell surface antigens of a mouse testicular teratoma. Identification of an
      antigen physically associated with H-2 antigens on tumor cells.
AB  - Rabbit antisera to a mouse testicular teratoma, absorbed with normal mouse
      tissues, react by immunofluorescence with plasma membrane antigens of a variety
      of transplantable mouse tumor cells and transformed fibroblast cell lines
      including Clone 1D, SV-40-3T3, and 3T12. Trypsin treatment of cells of "normal"
      lines, 3T3 and FR-SV-3T3, uncovers reactivity on these as well. Early passage
      mouse embryo fibroblast cell cultures do not react even after trypsinization. By
      cross-absorbtion studies, the anti-teratoma serum appears to react with an
      antigen common to most tumor cells investigated thus far. When this antigen on
      Clone 1D cells is "capped," H-2 antigens collect with the teratoma antigens in
      the cap indicating a physical association between the molecules. Molecules
      specified by both the H-2D and H-2K regions are bound to the teratoma antigens in
      the Clone 1D plasma membrane. This antigen is also found in soluble tumor cell
      fractions where it is believed to be free of H-2. A second cell surface antigen
      defined by anti-teratoma serum is expressed only by hepatoma and teratoma itself.
      This second antigen is apparently a secretory product of teratoma cells. A third
      surface antigen defined by anti-teratoma serum appears to be specific for the
      teratoma.

PMID- 4365515
TI  - Mediation of immunologic discharge of lysosomal enzymes from human neutrophils by
      guanosine 3',5'-monophosphate. Requirement of calcium, and inhibition by
      adenosine 3',5'-monophosphate.
AB  - The purpose of this investigation was to elucidate the relationship of cyclic GMP
      and calcium to the immunologic discharge of lysosomal enzymes from purified human
      neutrophils. Contact of neutrophils with a variety of immunologic stimuli,
      including zymosan particles treated with either normal or rheumatoid arthritic
      (RA) serum, heat-aggregated (agg) IgG, particulate and immobilized agg IgG each
      treated with RA serum, and zymosan-treated serum, provoked the discharge of beta
      glucuronidase, but not cytoplasmic lactate dehydrogenase, and stimulated the
      accumulation of cyclic GMP. Both enzyme release and elevation of cyclic GMP
      levels required the presence of extracellular calcium as neither cellular event
      proceeded in its absence. Cholinergic enhancement of the immunologic secretion of
      beta-glucuronidase from neutrophils by acetylcholine was associated with a
      concomitant accumulation of cyclic GMP. These actions of acetylcholine on
      neutrophils did not proceed in the absence of extracellular calcium. Whereas the
      concentrations of cyclic GMP in neutrophils were elevated by both immune
      reactants and a combination of the latter and acetylcholine, cyclic AMP levels
      remained unaltered. Thus, cyclic GMP, but not cyclic AMP, was associated with the
      immunologic and pharmacologic discharge of lysosomal enzymes from neutrophils.
      Contrariwise, cyclic AMP, but not cyclic GMP, was associated with inhibition of
      lysosomal enzyme release. For example, dibutyryl cyclic AMP and epinephrine
      inhibited the release of beta-glucuronidase from neutrophils that was elicited by
      each of the immune reactants tested. Moreover, cyclic AMP levels in the cells
      were elevated markedly in every instance that enzyme discharge was inhibited by
      epinephrine. Epinephrine did not alter the neutrophil concentrations of cyclic
      GMP at times when those of cyclic AMP were elevated. The data in this report
      constitute partial evidence that the immunologic discharge of lysosomal enzymes
      from human neutrophils is mediated or signaled by intracellular cyclic GMP and
      that calcium is linked to this stimulation of enzyme secretion.

PMID- 4365516
TI  - Ultrastructure of xanthelasma palpebrarum as revealed by freeze etching
      techniques.

PMID- 4365517
TI  - [Ultrastructure of inborn errors of keratinization. IV. X-linked recessive
      ichthyosis (author's transl)].

PMID- 4365518
TI  - [Endocrine cycles and paradoxal sleep].

PMID- 4365519
TI  - Pathogenesis of infectious bovine rhinotracheitis (IBR) virus infection in bovine
      fetal tracheal organ cultures.

PMID- 4365520
TI  - Studies on the unmasking and-or carrier effects of vesicular stomatitis virus
      grown in human lymphocytes.

PMID- 4365521
TI  - Pancreatitis of mice infected with encephalomyocarditis virus.

PMID- 4365522
TI  - [Electron-microscope studies of structural changes in the pigment epithelium of
      the human retina (author's transl)].

PMID- 4365523
TI  - In vitro effects of synthetic somatotropin-release inhibiting factor on cyclic
      AMP level and GH release in rat anterior pituitary gland.

PMID- 4365524
TI  - ['Fingerprint'-inclusions in the orbicular muscle of the eye].

PMID- 4365525
TI  - A papovavirus isolated from patients with progressive multifocal
      leukoencephalopathy.

PMID- 4365526
TI  - Virus antibodies in patients with multiple sclerosis.

PMID- 4365527
TI  - Editorial: Bronchial asthma.

PMID- 4365529
TI  - Editorial: Japanese encephalitis in India.

PMID- 4365528
TI  - Mixed tumour in an ectopic salivary gland.

PMID- 4365530
TI  - The distribution of 14C-label in the lipids of ram semen following the
      intratesticular injection of (1-14C)palmitic acid.

PMID- 4365531
TI  - Actions of antifertility chemicals on Xenopus laevis spermatozoa in vitro.

PMID- 4365532
TI  - Interaction of prostaglandins E1 and E2 in regulation of cyclic-AMP and
      aggregation in human platelets: evidence for a common prostaglandin receptor.

PMID- 4365533
TI  - Relation of nucleoside transport and surface phosphohydrolase activity in
      Hymenolepis diminuta.

PMID- 4365534
TI  - On the treatment with proflavine of herpes simplex or vaccinia infected GMK
      cells. An electron microscopic study.

PMID- 4365535
TI  - Genetic control of some metabolic modifications during the sporulation of
      Saccharomyces cerevisiae Hansen.

PMID- 4365536
TI  - Influence of dilution rate on enzyme synthesis in Aspergillus niger in continuous
      culture.

PMID- 4365537
TI  - Enzymes of arginine biosynthesis and their repressive control.

PMID- 4365538
TI  - Aminoacyl-tRNA synthetases: sone recent results and achievements.

PMID- 4365539
TI  - Clinical care of nonhuman primates. Synopsis and evaluation of a workshop held at
      the National Institutes of Health, Bethesda, MD., 7-8 March 1973.

PMID- 4365540
TI  - Methods for the separation of platelets from plasma. A comparison of functional
      and morphological integrity.

PMID- 4365541
TI  - The influence of benzamidine derivatives on human platelet function.

PMID- 4365542
TI  - Time of appearance of the distal sesamoidean loci of ossification of the calf.

PMID- 4365543
TI  - Rapid identification of swine vesicular disease virus in vesicular epithelium
      using the fluorescent antibody technique.

PMID- 4365544
TI  - Bacterial attack on phenolic ethers. Electron acceptor-substrate binding proteins
      in bacterial O-dealkylases: purification and characterization of cytochrome P
      450npd of Nocardia.

PMID- 4365545
TI  - Biosynthesis of lipovitellin by the crustacean ovary.

PMID- 4365546
TI  - The effects of an elevated temperature, colchicine, and vinblastine on axonal
      microtubules of the crayfish (Procambarus clarkii).

PMID- 4365547
TI  - Isolation and characterization of phenothiazine-copper complexes.

PMID- 4365549
TI  - [Preparation and study of adenovirus type-specific antihemagglutinin sera and its
      value in immunodiffusion diagnostic procedures].

PMID- 4365550
TI  - [Ultrastructure and morphogenesis of type-C virus particles in bovine enzootic
      leucosis].

PMID- 4365551
TI  - [The density of the foot-and-mouth disease virus in CsCl solutions].

PMID- 4365552
TI  - A Meckel-like syndrome?

PMID- 4365553
TI  - Purification and biochemical properties of genetically defined malate
      dehydrogenase in maize.

PMID- 4365554
TI  - A new procedure for synthesis of 3-keto derivatives of sphingolipids and its
      application for study of fatty acid composition of brain ceramides and
      cerebrosides containing dihydrosphingosine of sphingosine.

PMID- 4365555
TI  - Membrane phospholipids and hormone-sensitive lipolysis in fat cells.

PMID- 4365556
TI  - Morphological and biochemical studies on liver biopsies of parkinsonian patients
      treated with levodopa and decarboxylase inhibitor.

PMID- 4365557
TI  - [Epidemiology and prophylaxis of viral hepatitis].

PMID- 4365559
TI  - The effect of sex on certain properties of the very low density lipoprotein
      secreted by the liver.

PMID- 4365558
TI  - The effect of catecholamines and fasting on cyclic-AMP and release of glycerol
      from human adipose tissue.

PMID- 4365560
TI  - Cobalt--bis(histidine methyl ester) deuteroporphyrine IX: a coenzyme B12--related
      model.

PMID- 4365561
TI  - A Neurospora crassa morphological mutant showing reduced adenylate cyclase
      activity.

PMID- 4365562
TI  - Lysophospholipid induced volume changes in lysosomes and in lysosomal lipid
      dispersions.

PMID- 4365563
TI  - Phosphoglycerate kinase (GTP). An enzyme from Entamoeba histolytica selective for
      guanine nucleotides.

PMID- 4365565
TI  - [Possibilities of radiologic diagnosis of insulinoma].

PMID- 4365564
TI  - (3H)norepinephrine binding: unrelated to catechol-O-methyl transferase.

PMID- 4365567
TI  - Editorial: The diagnostic tripod.

PMID- 4365566
TI  - [Lymphography in childhood cancer (author's transl)].

PMID- 4365568
TI  - Letter: Test for role of angiotensin in hypertension.

PMID- 4365569
TI  - Regularity in the control of the free-running sleep-wakefulness rhythm.

PMID- 4365570
TI  - Regulation of melanocyte stimulating hormone action at the receptor level:
      discontinuous binding of hormone to synchronized mouse melanoma cells during the
      cell cycle.
AB  - Melanocyte stimulating hormone coupled to Sepharose effects an increase in
      tryosinase (EC 1.14.18.1; monophenol monoxygenase) activity of cultivated mouse
      melanoma cells. Synchronized cells are found to respond to melanocyte stimulating
      hormone only in the G2 phase of the cell cycle, although their response to cyclic
      AMP is independent of position in the cell cycle. The binding of (125)I-labeled
      melanocyte stimulating hormone occurs predominantly in G2. These observations are
      satisfied by a model in which the hormone can activate adenylate cyclase (EC
      4.6.1.1) by binding to a melanocyte stimulating hormone receptor only in G2; the
      events distal to cyclic AMP production can occur throughout the cell cycle.

PMID- 4365571
TI  - Non-selective inhibition of transformed cell growth by a protease inhibitor.
AB  - The protease inhibitors N-tosyl-L-phenylalanylchloromethyl ketone (TPCK) and N
      tosyl-L-lysylchloromethyl ketone (TLCK) have previously been shown to selectively
      inhibit growth of simian virus 40-transformed cells, suggesting that proteolytic
      enzymes play a role in loss of cellular growth control following viral
      transformation. In contrast, this study shows that TPCK-mediated growth
      inhibition is non-selective, since the growth of both simian virus 40-transformed
      and untransformed 3T3 cells is similarly reduced by TPCK treatment. Under certain
      conditions, TPCK treatment of simian virus 40-transformed cells yields a
      reversible "growth plateau" condition which mimics, but is not equivalent to,
      contact inhibition of growth. The growth inhibitory effects of TPCK are due to
      inhibition of protein synthesis, since TPCK treatment resulted in a diminution of
      protein synthesis and since the "growth plateau" effect was also observed in
      cultures treated with cycloheximide.

PMID- 4365572
TI  - Changes in activity and molecular properties of fructose 1, 6-bisphosphatase
      during fasting and refeeding.
AB  - During prolonged starvation, fructose 1,6bisphosphatase (EC 3.1.3.11) activity in
      rabbit liver and kidney shows a transient decrease during the first 36 hr, before
      rising at 96 hr to levels severalfold higher than those found in the livers of
      fed animals. Proteolytic activity appears in the 105,000 x g supernatant fraction
      within several hours of starvation, and continues to increase during the entire
      96-hr period. On refeeding, the activities return to nearly the control levels
      within 24 hr. The catalytic properties of fructose 1,6-bisphosphatase isolated
      from the livers of fasted rabbits are similar to those of the enzyme from fed
      animals, but its structure is modified, since it no longer contains the single
      tryptophan residue located near the NH(2)-terminus in the native enzyme. Thus
      this tryptophan residue is not required for the neutral pH optimum. The
      structural changes and the transient decrease in activity may be related to the
      observed increase in "free" proteolytic activity.

PMID- 4365574
TI  - Visualization of single-stranded nucleic acid of RNA tumor virus with the
      electron microscope.
AB  - 60-70S RNA of avian myeloblastosis virus was spread with the Kleinschmidt method
      and examined in the electron microscope after being subjected to a variety of
      denaturing conditions. Extension of the molecules from a collapsed configuration
      was seen only under stringent denaturing conditions, resulting in molecules of 1
      2 mum in length. Longer strands of these extremely fragile molecules cannot be
      obtained with the methods presently available.

PMID- 4365573
TI  - Enzyme activity in invasive tumors of human breast and colon.
AB  - Elevated levels of glycoprotein:sialyltransferase activity (EC 2.4.99.1; CMP-N
      acetylneuraminate: D-galactosyl-glycoprotein N-acetylneuraminyltransferase) were
      found in human malignant neoplastic tissues compared to normal, benign, and
      "preneoplastic" tissues. This increase was not due to the cell density of the
      tissue. Elevated levels of certain proteases and glycosidases were also found.
      The increase in transferase activity may be associated with altered membrane
      synthesis in the neoplastic state; changes in the activity of degradative enzymes
      may be associated with tumor invasiveness and maintenance of the neoplastic
      state. Measurements on human tumors are possibly more directly relevant to cancer
      than those described for transformed fibroblastic cells in vitro.

PMID- 4365575
TI  - Guanosine 3':5'-cyclic monophosphate-dependent phosphorylation of endogenous
      substrate proteins in membranes of mammalian smooth muscle.
AB  - Guanosine 3':5'-cyclic monophosphate (cyclic GMP) stimulated the endogenous
      phosphorylation of two proteins in isolated membrane fractions from mammalian
      organs rich in smooth muscle, including ductus deferens, uterus, and small
      intestine. The apparent molecular weights of the substrate proteins were 130,000
      and 100,000. In the presence of 10 mM MnCl(2), a half-maximal increase in
      phosphorylation of these proteins was achieved with 20-30 nM cyclic GMP.
      Approximately 10-fold higher concentrations of adenosine 3':5'-cyclic
      monophosphate (cyclic AMP) were required to produce the same increase in
      phosphorylation of these two proteins. Cyclic AMP, but not cyclic GMP, regulated
      the phosphorylation of a third protein present in these same membrane fractions;
      the apparent molecular weight of this protein was 50,000. Cyclic GMP-dependent
      phosphorylation of endogenous protein was not observed in the cell sap of any of
      the three preparations of smooth muscle studied. The finding of endogenous cyclic
      GMP-dependent protein kinase activity and associated substrate proteins in
      membrane fractions from several mammalian organs containing smooth muscle raises
      the possibility that physiological actions of cyclic GMP in smooth muscle may be
      mediated by the phosphorylation of membrane proteins.

PMID- 4365576
TI  - Investigation of very slowly tumbling spin labels by nonlinear spin response
      techniques: theory and experiment for stationary electron electron double
      resonance.
AB  - The investigation of very slowly tumbling spin labels by nonlinear electron spin
      response techniques is discussed. Such techniques permit characterization of
      rotational processes with correlation times from 10(-3) to 10(-7) sec even though
      the linear spin response (ESR) technique is insensitive to motion in this region.
      Nonlinear techniques fall into two categories: (a) Techniques (referred to as
      passage techniques) in which the distribution of saturation throughout the spin
      system is determined both by the applied magnetic field modulation of the
      resonance condition and by the modulation of the resonance frequency induced by
      the molecular motion. The time dependence of this distribution produces phase and
      amplitude changes in the observed signals. (b) Techniques that measure the
      integral of the distribution function of the time required for saturated spin
      packets to move between pumped and observed portions of the spectrum [stationary
      and pulsed electron electron double resonance (ELDOR) techniques]. Quantitative
      analysis of passage ESR and stationary ELDOR techniques can be accomplished
      employing a density matrix treatment that explicitly includes the interaction of
      the spins with applied radiation and modulation fields. The effect of molecular
      motion inducing a random modulation of the anisotropic spin interactions can be
      calculated by describing the motion by the diffusion equation appropriate to the
      motional model assumed. For infinitesimal steps the eigen-functions of the
      diffusion operator are known analytically, while for random motion of arbitrary
      step size they are determined by diagonalizing the transition matrix appropriate
      for the step model used. The present communication reports investigation of the
      rotational diffusion of the spin label probes 2,2,6,6-tetramethyl-4-piperidinol-1
      oxyl and 17beta-hydroxy-4',4'-dimethylspiro-[5alpha-androstane-3,2'-oxazolidin]
      3'-oxyl in sec-butylbenzene. Experimental spectra are compared with computer
      simulations of spectra carried out for isotropic Brownian (limit of infinitesimal
      step size) and free diffusion (arbitrary step size) models.

PMID- 4365577
TI  - Widespread natural occurrence of high titers of neutralizing antibodies to a
      specific class of endogenous mouse type-C virus.
AB  - Mouse cells contain several biologically distinguishable endogenous type-C
      viruses. In the present studies, the immunologic response of different strains of
      mice to the natural expression of these viruses has been examined. High titers of
      neutralizing antibodies have been detected to a class of virus that lacks the
      ability to exogenously infect mouse cells. The expression of this virus, in vivo
      as well as in vitro, is shown to be vertically transmitted as a dominant genetic
      trait. The findings indicate the widespread occurrence of this endogenous virus
      and the ability of the mouse to immunologically respond to a class of type-C
      virus whose mode of transmission is similar to that of cellular genes.

PMID- 4365578
TI  - Accumulation of an intermediate in DNA synthesis by HEp.2 cells treated with
      methyl methanesulfonate.
AB  - A portion of the DNA synthesized by HEp.2 cells after short incubation in the
      presence of BrdU bands in a CsCl gradient at a distinct peak of density 1.715
      1.718 g/cm(3). Inhibition of DNA synthesis by methyl methanesulfonate results in
      an increased proportion of this "intermediate density" DNA. Cells labeled and
      subsequently chased in nonradioactive BrdU yield only hybrid DNA. Treatment with
      single-strand-specific deoxyribonuclease converts a portion of the intermediate
      density material to molecules of hybrid density (1.755 g/cm(3)). The data suggest
      an intermediate in DNA replication that contains a single-stranded region in the
      parental strand and that accumulates when DNA synthesis is blocked by an
      alkylation-induced lesion.

PMID- 4365579
TI  - Mechanism of enzymic acetylation of des-acetyl citrate lyase.
AB  - A new enzyme, acetate:SH-[acyl-carrier-protein] enzyme ligase (AMP), has been
      purified about 30-fold from cell-free extracts of Klebsiella aerogenes. The
      enzyme, in the presence of acetate and ATP, catalyzes the acetylation of
      enzymically inactive des-acetyl citrate lyase to enzymically active citrate lyase
      (EC 4.1.3.6). Acetate and ATP could be replaced by acetyl adenylate. Acetyl-CoA
      can act as acetyl donor in this activation only if trace amounts of adenine
      nucleotides and auxiliary enzymes are present. These allow formation of acetyl
      adenylate in acetate- and ATP-generating reactions.

PMID- 4365580
TI  - Differences in membrane fluidity and structure in contact-inhibited and
      transformed cells.
AB  - Studies on contact-inhibited mouse embryo fibroblast 3T3 cells and 3T3 cells
      transformed by oncogenic RNA and DNA viruses and by a chemical carcinogen have
      demonstrated differences in plasma membrane architecture. Spin-label and freeze
      fracture ultrastructural studies have shown that contact-inhibited cells have
      ordered membrane lipids and aggregated intramembranous particles, whereas
      transformed cells have fluid membrane lipids and randomly distributed
      intramembranous particles. These findings suggest a model for how changes in the
      cell membrane may account for some of the characteristic differences observed
      between contact-inhibited and transformed cells.

PMID- 4365581
TI  - An RNA-dependent nucleoside triphosphate phosphohydrolase (ATPase) associated
      with rho termination factor.
AB  - Highly purified rho termination factor from Escherichia coli catalyzes an RNA
      dependent hydrolysis of ribonucleoside triphosphates to nucleoside diphosphates
      and inorganic phosphate. In the presence of poly(C), a specific activity of 100
      mumole of ATP hydrolyzed per min/mg has been measured. The phosphohydrolase
      activity appears to be associated with the protein responsible for termination of
      RNA synthesis, but a functional relationship between the two activities is not
      yet evident. Hydrolysis of nucleoside triphosphates occurs in the absence of
      termination and without any extensive degradation of RNA.

PMID- 4365583
TI  - Specific movement of cell membranes fused with HVJ (Sendai virus).
AB  - When Ehrlich ascites tumor cells fused with UV-inactivated HVJ (Sendai virus)
      were cultured, the viral envelope antigens, which had been integrated at random
      into the cell membranes, accumulated at one site on the fused cell. The site
      showed a specific structure, namely, a projection of the cytoplasm from the
      spherical fused cell surface with clusters of many long microvillilike
      protrusions from it. When the fused cells were conjugated with antibody against
      Ehrlich ascites tumor cells and cultured, the antigen-antibody complex also
      accumulated on the projection.Associated with the development of the projection
      and accumulation of viral antigens, vacuoles developed at the base of the
      projection in the cytoplasm of the fused cells in culture. The development of the
      projection and vacuoles and the accumulation of viral antigens were all inhibited
      by glucose, mannose, galactose, sodium azide, and cycloheximide, and these
      inhibitions were reversible. All these structures were observed in multinucleated
      cells, but few in mononucleated cells after reaction with HVJ (Sendai virus). We
      consider that these three phenomena correlate with each other and may result from
      changes in cell-membrane systems caused by fusion of cells.

PMID- 4365582
TI  - Spontaneous induction of endogenous murine leukemia virus-related antigen
      expression during short-term in vitro incubation of mouse lymphocytes.
AB  - Short-term lymphocyte cultures from mouse thymus, spleen, or lymph nodes were
      studied for the presence of murine leukemia virus group-specific antigens with an
      immunofluorescence test using rat immune sera against syngeneic cells infected
      with the radiation leukemia virus or its pseudotype of murine sarcoma virus and
      goat and rabbit antisera against purified murine leukemia virus group-specific
      antigen. Antigens reacting with these sera appeared in the cultured lymphocytes
      within 24 hr, and the proportion of immunofluorescent-positive cells increased to
      25-80% by the second or third day of cultivation, concomitantly with a decrease
      in cell viability. The appearance of these antigens can be suppressed by
      inhibitors of DNA (mitomycin-C), RNA (actinomycin-D, cordycepin, and polyadenylic
      acid), and protein (cycloheximide) synthesis. No infectious virus could be
      detected by the immunofluorescence and XC-cell tests. The observed phenomenon
      appears to represent the spontaneous partial derepression of endogenous murine
      leukemia virus replication in lymphocytes during short-term in vitro cultivation.

PMID- 4365584
TI  - Discontinuous variability, in the form of a geometric progression, of albumin
      production in hepatoma and hybrid cells.
AB  - A clonal rat hepatoma cell line (Fu5) produces rat serum albumin at a constant
      rate over at least 3 months of continuous cultivation. Ten hybrid cell clones
      derived from the fusion of Fu5 cells and mouse fibroblasts, as well as 14
      hepatoma subclones of Fu5 cells, all produce albumin but at different rates,
      ranging from about 0.09 to 36.7 mug/mg of protein per 72 hr. Despite this
      variability in albumin production, the distribution of clones is not random but
      discontinuous, with both hepatoma and hybrid clones clustering around discrete
      values that can be fitted to the geometric progression: a, a( radical2)(1), a(
      radical2)(2)..... a( radical2)(n). The values of the majority of clones fall into
      alternate members of this geometric progression, which differ by a factor of 2.
      Hepatoma subclones with indistinguishable karyotypes differ in level of albumin
      production by as much as 4-fold. In contrast to hepatoma clones, albumin
      production in hybrid clones decreases with increasing cell generations. A survey
      of 28 enzymes of different hepatomas reveals a large variability in enzyme levels
      which, for most enzymes, can be arranged into classes that form a geometric
      progression. The apparent widespread nature of this discontinuous phenotypic
      variability suggests that it may reflect a basic mechanism of control of gene
      expression in animal cells.

PMID- 4365585
TI  - Polyoma DNA: a physical map.
AB  - The action of restriction enzymes on polyoma DNA was studied with uniformly (32)P
      labeled viral DNA obtained from either infected 3T6 or secondary mouse-embryo
      cells. Three restriction enzymes were used to construct a physical map of the
      polyoma genome. An enzyme from Hemophilus parainfluenzae, Hpa(II), cleaved polyma
      DNA into eight unique fragments (Hpa(II)-1 to Hpa(II)-8), ranging in size from
      27.3 to 1.8% of the genome. An enzyme from Hemophilus influenzae, Hin(III), gave
      two fragments (56 and 44%); and a third enzyme from Escherichia coli, EcoR(I),
      cut at a single unique site. The physical map of the polyma genome was
      constructed from methods involving: (1) further digestion of the fragments
      produced by enzymes EcoR(I) and Hin(III) with Hpa(II), and (2) analysis of the
      products of partial digestion with Hpa(II). Analysis by electron microscopy of
      replicating DNA molecules (less than 50% replicated) cut with the Hin(III)
      enzyme, in combination with other studies, has indicated that the origin of DNA
      replication is located at 71 +/- 3 map units from the EcoR(I) cleavage site,
      probably in Hpa(II)-5.

PMID- 4365586
TI  - Evidence for the in vivo regulation of glucose 6-phosphate dehydrogenase activity
      in Hydrogenomonas eutropha H 16 from measurements of the intracellular
      concentrations of metabolic intermediates.

PMID- 4365587
TI  - [Estrogen treatment of women after the menopause].

PMID- 4365588
TI  - Aspirin and analgin as analgesics.

PMID- 4365589
TI  - Carbohydrate transport and cyclic 3',5' adenosine monophosphate (cAMP) levels in
      a temperature sensitive phosphotransferase mutant of Escherichia coli.

PMID- 4365590
TI  - Physiological and endocrinological changes in response to terminal heat stress in
      swine.

PMID- 4365591
TI  - [Skin resorptive effect of the fumes of hydrogen fluoride].

PMID- 4365592
TI  - [Vaginism].

PMID- 4365593
TI  - [Primary hepatocellular carcinoma with increased TBG and free thyroxine].

PMID- 4365594
TI  - An autopsy case of isolated myocarditis probably associated with infectious
      mononucleosis and disseminated cytomegalic inclusion disease.

PMID- 4365596
TI  - Letter: Estrogenic substances in beef.

PMID- 4365595
TI  - Reciprocal influence of salt intake on adrenal glomerulosa and renal vascular
      responses to angiotensin II in normal man.
AB  - The adrenal glomerulosa cell and the renal vasculature respond to similar
      arterial angiotensin II (A II) levels. We have assessed the effect of decreased
      sodium intake on their responses to A II in man. Studies were performed in 42
      normal subjects in balance on a daily intake of 100 meq potassium and either 200
      or 10 meq sodium/day. Renal blood flow was measured with (133)Xe and arterial A
      II, renin and aldosterone concentrations by radioimmunoassay. A II was infused
      intravenously (1, 3, or 10 ng/kg/min) for 40-60 min; 14 subjects received graded
      doses. The A II level increased linearly with dose and plateaued within 3 min;
      blood pressure and renal vascular resistance showed a similar time-course.
      Aldosterone rose within 10 and plateaued within 20 min. Dose-response
      relationships were established between the rate of A II infusion and the adrenal,
      the renal vascular, and pressor responses. Sodium restriction reduced the pressor
      (P < 0.01) and the renal vascular response (P < 0.01), but potentiated the
      adrenal response to A II (P < 0.01). An excellent correlation was found between
      the plasma A II and aldosterone levels, but the slope of their regression
      relationship on a high (y = 0.13x + 6) and low salt intake (y = 0.32x + 14)
      differed significantly (P < 0.0005). Thus, sodium intake reciprocally influences
      vascular and adrenal responses to A II: salt restriction blunts the vascular
      response and potentiates the adrenal's, a physiologically important influence in
      view of aldosterone's role in sodium conservation.

PMID- 4365597
TI  - Genital herpes. Some clinical and laboratory observations.

PMID- 4365598
TI  - Growth quantitation of human mammary carcinoma in organ tissue culture.

PMID- 4365599
TI  - Relationship of the adrenergic nervous system and growth hormone release in
      normal adults and children with various growth disorders.

PMID- 4365600
TI  - Renal vein native plasma pressor activity.

PMID- 4365601
TI  - [Interrelation of metabolism of inorganic polyphosphates and mannan in yeasts].

PMID- 4365602
TI  - Isolation of reovirus type 1 from lambs showing respiratory and intestinal
      symptoms.

PMID- 4365603
TI  - Isolation of rhinovirus from cattle in outbreaks of acute respiratory disease.

PMID- 4365605
TI  - Further characterization of infectious hematopoietic necrosis virus of salmonid
      fish (Oregon strain).

PMID- 4365604
TI  - [A latex agglutination-inhibition test for demonstrating antibodies against
      enteroviruses (author's transl)].

PMID- 4365606
TI  - Effects of cytochrome C on the liver function of aged rats.

PMID- 4365607
TI  - Mechanism of bufalin-induced blockade of neuromuscular transmission in isolated
      rat diaphragm.

PMID- 4365608
TI  - [Stability of some antibiotics in medicated feed and milkreplacers (author's
      transl)].

PMID- 4365609
TI  - [Photosensitization of cytochrome C transformations by chlorophyll: activating
      effect of quinones].

PMID- 4365610
TI  - [Oligomers of the replicative form of encephalomyocarditis virus RNA].

PMID- 4365611
TI  - [Variations in the intensity of H3-leucine incorporation into proteins during
      slow-wave and paradoxical phases of natural sleep in the cat associative cortex].

PMID- 4365612
TI  - Sleep patterns in the pony with observations on partial perceptual deprivation.

PMID- 4365613
TI  - Spectral analysis of hippocampal slow wave activity during feeding and drinking
      in the rabbit.

PMID- 4365614
TI  - [Current aspects of clinical osteology from the viewpoint of medicine].

PMID- 4365615
TI  - [Current aspects of clinical osteology from radiological point of view].

PMID- 4365617
TI  - [Malignant metastasizing Abrikossov's granular cell myoblastoma with symptomatic
      dermatomyositis].

PMID- 4365616
TI  - [Clinical picture of rheumatic diseases. Experiences with interval corticoid
      therapy].

PMID- 4365618
TI  - Responsiveness of lymphocytes from Mengovirus treated mice to phytohaemagglutinin
      stimulation, in vitro.

PMID- 4365619
TI  - Specific induction of transitions and transversions of G-C base pairs by 4
      nitroquinoline-1-oxide in iso-1-cytochrome c mutants of yeast.

PMID- 4365620
TI  - Specificity and frequency of ultraviolet-induced reversion of an iso-1-cytochrome
      c ochre mutant in radiation-sensitive strains of yeast.

PMID- 4365621
TI  - Acute suppurative amebic pericarditis.

PMID- 4365622
TI  - Inhibition of glucagon-mediated increases in hepatic cyclic adenosine 3', 5'
      monophosphate by prostaglandin E1 and E2.

PMID- 4365623
TI  - Nuclear receptor estradiol complex: a requirement for uterotrophic responses.

PMID- 4365624
TI  - Initiation of luteinization in rabbit Graafian follicles by dibutyryl cyclic AMP
      in vitro.

PMID- 4365625
TI  - Binding of luteinizing hormone and human chorionic gonadotrophin to ovarian cells
      and activation of adenylate cyclase.

PMID- 4365626
TI  - Proceedings: Further investigations on the effects of adrenalectomy and pituitary
      adrenocortical hormone treatments on isolation-induced fighting behaviour in male
      albino mice.

PMID- 4365627
TI  - Proceedings: Changes in kallikrein excretion during arterial infusion of
      angiotensin.

PMID- 4365628
TI  - Proceedings: Effect of angiotensin II on cyclic AMP and corticosterone output by
      purified zona glomerulosa and zona fasciculata cells of the rat adrenal cortex.

PMID- 4365629
TI  - Red blood cell drug binding as a possible mechanism for tranquilization.

PMID- 4365630
TI  - Mode of action of mucidin, a new antifungal antibiotic produced by the
      basidiomycete Oudemansiella mucida.

PMID- 4365631
TI  - Inhibition by several standard antiprotozoal drugs of growth and O2 uptake of
      cells and particulate preparations of a Leptomonas.

PMID- 4365632
TI  - Biochemical cytology of trichomonad flagellates. II. Subcellular distribution of
      oxidoreductases and hydrolases in Monocercomonas sp.

PMID- 4365633
TI  - Stimulation of cyclic adenosine 3',5'-monophosphate accumulation and lipolysis in
      fat cells by adenosine deaminase.

PMID- 4365634
TI  - [Prognosis of the idiopathic nephrotic syndrome in children].

PMID- 4365635
TI  - Renal morphological and immunological changes associated with acute viral
      hepatitis.

PMID- 4365636
TI  - The renin system: Variations in man measured by radioimmunoassay or bioassay.

PMID- 4365637
TI  - Enzyme activities of the single juxtaglomerular apparatus in the rat kidney.

PMID- 4365638
TI  - [Bacterial enzymology: adenylate cyclase].

PMID- 4365639
TI  - [Symposium I: Structure and function of cilia of Bordetella pertussis].

PMID- 4365640
TI  - [Symposium II: Gas gangrene and toxins].

PMID- 4365641
TI  - Exocellular pyruvate-containing galactoglucan of Achromobacter spp.

PMID- 4365642
TI  - Pinocytotic uptake of protein from the reservoir in Euglena.

PMID- 4365643
TI  - The cytochromes of some hydrogen bacteria.

PMID- 4365644
TI  - Bio-degradation and utilization of silica and quartz.

PMID- 4365645
TI  - Chromatographic preparation of purified structural proteins from foot-and-mouth
      disease virus.

PMID- 4365646
TI  - Comparison of large fragments obtained by T1 RNase digestion of ribosomal and
      nucleolar preribosomal RNA of Novikoff hepatoma ascites cells: the 5'-terminal
      eicosanucleotide.

PMID- 4365647
TI  - Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible
      mechanism for paraquat (methyl viologen) toxicity.

PMID- 4365648
TI  - Nucleotide clusters in in deoxyribonucleic acids. X. Sequences of the pyrimidine
      oligonucleotides of mouse L-cell satellite DNA.

PMID- 4365649
TI  - Regulation of herpes simplex virus-induced thymidine kinase.

PMID- 4365650
TI  - [Orthodontic indications for the extraction of milk teeth].

PMID- 4365651
TI  - [A case of nystagmus retractorius with Parinaud's syndrome in peduncular
      ischemia].

PMID- 4365652
TI  - Inactivation of Sabin oral poliomyelitis type I virus.

PMID- 4365653
TI  - Proceedings: Influence of dibutyryl cyclic AMP on the K+-contracture of guinea
      pig trachea.

PMID- 4365654
TI  - Proceedings: Changes of the level of cyclic AMP in carrageenin granuloma.

PMID- 4365655
TI  - Proceedings: Electrophysiological studies on adenyl cyclase-cyclic AMP system in
      the fat cell membrane.

PMID- 4365656
TI  - Proceedings: Thiamine metabolism in the central nervous system. 2. Effects of
      psychotropic drugs on rat brain thiamine di- and tri-phosphatase.

PMID- 4365657
TI  - Proceedings: Relation between hyperkalemia and hyperglycemia. 9.

PMID- 4365658
TI  - Proceedings: Influence of the nucleus dorsalis on neuron activities of the spinal
      trigeminal nucleus.

PMID- 4365659
TI  - Proceedings: Influence of the nucleus dorsalis on neuron activities of the spinal
      trigeminal nucleus.

PMID- 4365660
TI  - Proceedings: Effects of ATP on sympathetic ganglia from bullfrog.

PMID- 4365661
TI  - Proceedings: Biochemical studies on the mechanism of action of a new anti
      inflammatory agent, naproxen. 2. Effects of naproxen on mucopolysaccharase,
      protease and collagenolytic enzyme activities in inflamed tissues of filter paper
      implanted rats.

PMID- 4365662
TI  - [Serum lipids levels, lipoprotein phenotypes and analysis of lipoprotein in
      Italian population group (author's transl)].

PMID- 4365663
TI  - Ocular findings in leprosy.

PMID- 4365664
TI  - Polyamines in normal and in virus-transformed chick embryo fibroblasts.

PMID- 4365666
TI  - Neurotoxicity of commonly used antineoplastic agents (second of two parts).

PMID- 4365665
TI  - Trial of a bacterial screening system for rapid detection of mutagens and
      carcinogens.

PMID- 4365667
TI  - Cytomegalovirus in semen. Persistence and demonstration in extracellular fluids.

PMID- 4365668
TI  - Letter: Implications of cyclic adenosine 3',5'-monophosphate in chronic renal
      failure.

PMID- 4365669
TI  - Esophageal varices. Development secondary to primary and metastatic liver tumors.

PMID- 4365670
TI  - Pneumonia in an intensive care unit. A 30-month experience.

PMID- 4365671
TI  - Letter: Gentamicin-resistant escherichia coli.

PMID- 4365672
TI  - Subcellular localization of staphylococcal enterotoxin B in rabbit kidney.

PMID- 4365674
TI  - Effect of cyclic AMP, caffeine and theophylline on differentiation of lens
      epithelial cells.

PMID- 4365673
TI  - Physicochemical properties of plasma renin substrate in normal, binephrectomized,
      and estrogen-treated rats.

PMID- 4365675
TI  - Some observations on spontaneously occurring tumours of the central nervous
      system of Sprague-Dawley derived rats.

PMID- 4365676
TI  - Pressor substances in the posthemodialysis dialysates of patients with toxemia of
      pregnancy.

PMID- 4365677
TI  - Rous sarcoma virus-transformed hamster tumor cells resistant to 5
      bromodeoxyuridine.

PMID- 4365678
TI  - Relationship between hydration and proton nuclear magnetic resonance relaxation
      times in tissues of tumor-bearing and non-tumor-bearing mice: implications for
      cancer detection.

PMID- 4365679
TI  - Adult and embryonic gecko cells in vitro: growth characteristics, infection by
      rabies, sindbis and polyoma viruses, and transformation by SV40.

PMID- 4365680
TI  - Structure-function relationships in phosphoinositides.

PMID- 4365681
TI  - Extraction and production of renin and angiotensin II across several vascular
      beds in dogs.

PMID- 4365683
TI  - Biochemical changes in cottonseed during germination.

PMID- 4365682
TI  - [The pathogenesis of Darier-Gronblad-Strandberg syndrome (author's transl)].

PMID- 4365684
TI  - Vestibulospinal effects on hindlimb motoneurons of the frog.

PMID- 4365685
TI  - Hormonally enhanced proliferation of human breast cancer in organ culture. An in
      vitro system for assessment of specific hormonal response.

PMID- 4365686
TI  - Radiologic assessment of the facial nerve.

PMID- 4365687
TI  - Dibutyryl cyclic 3':5'-adenosine monphosphate in hypopituitarism and Silver
      Russell syndrome.

PMID- 4365688
TI  - [On the distribution and prevalence of parasitic infections in various regions of
      the Iran (author's transl)].

PMID- 4365689
TI  - [Beginning of an experiment with a center for psychiatric after care].

PMID- 4365690
TI  - [Guiding principles and initial results of an intensive psychotherapy center for
      young psychotics, centered on communication and autonomy].

PMID- 4365691
TI  - [6 months of activities of the Center for Social Readaptation and Productive
      Reintegration].

PMID- 4365692
TI  - Radioimmunoassays.

PMID- 4365693
TI  - Laboratory recognition of coronary artery disease (with a review of the surgical
      treatment).

PMID- 4365694
TI  - [Electroencephalographical studies on the actions of hypnotic agents. 1. Effects
      of various hypnotic agents on the sleep and wakefulness cycle in the rabbit].

PMID- 4365695
TI  - [Electroencephalography studies on the actions of hypnotic agents. 2. effects of
      various hypnotic agents on electrical activity of the lower brain stem of
      rabbits].

PMID- 4365696
TI  - Exercise after myocardial infarction.

PMID- 4365697
TI  - Hypothesis: hypothalamic dysfunction and lipoatrophic diabetes.

PMID- 4365698
TI  - Toxic proteins produced by Clostridium botulinum.

PMID- 4365699
TI  - Avian tumor virus RNA: a comparison of three sarcoma viruses and their
      transformation-defective derivatives by oligonucleotide fingerprinting and DNA
      RNA hybridization.
AB  - Earlier electrophoretic analyses have shown that the 60-70S RNA of avian sarcoma
      viruses contains a characteristic subunit, termed class a subunit, which has a
      lower electrophoretic mobility than class b subunit found in transformation
      defective derivatives of sarcoma viruses and in avian leukosis viruses. We have
      compared the RNAs of three nondefective avian sarcoma viruses, B77 and Prague and
      Schmidt-Ruppin strains of Rous sarcoma virus, with those of their transformation
      defective (td) derivatives, td B77, td PR-C, and td SR-A, respectively, to
      determine the chemical basis for the difference between class a and b subunits.
      It was found by "fingerprinting" that (1) all (about 20-25) large T1 RNase
      resistant oligonucleotides present in class b subunits of transformation
      defective viruses have homologous counterparts in the class a subunits of
      corresponding nondefective sarcoma viruses and that (2) class a subunits contain
      a few (one or two) additional oligonucleotides that are not present in class b.
      By contrast the oligonucleotide fingerprints of avian tumor viruses of different
      strains and subgroups were very different.Cross hybridization of classes a and b
      RNA of sarcoma virus B77 with DNA transcribed from a corresponding transformation
      defective virus td B77 showed that the two RNAs share at least 60% and differ by
      about 10% of their sequences. It is suggested that the structural relationship of
      class a and b subunits of corresponding viruses may be expressed as a = b + x,
      and that all the oligonucleotides present only in RNAs of sarcoma viruses but not
      in transformation-defective viruses of the corresponding strains are part of
      sequence(s) x. The possibility that x represents genetic information directly or
      indirectly involved in transformation of fibroblasts is discussed.

PMID- 4365700
TI  - Growth-and density-dependent inhibition of deoxyglucose transport in Balb 3T3
      cells and its absence in cells transformed by murine sarcoma virus.
AB  - The earliest measurable parameter that shows density-dependent inhibition is the
      uptake of [(3)H]deoxyglucose by Balb 3T3 cells. The rate decreases even during
      the exponential phase of growth and reaches a minimum, about 8- to 10-times lower
      than maximum, as the culture approaches the saturation density. Cells transformed
      by murine sarcoma virus fail to show either growth-dependent or density-dependent
      inhibition of deoxyglucose uptake. Treatment with dibutyryl cyclic AMP in the
      presence of theophylline results in premature cessation of growth and in an
      arrest in the decline of deoxyglucose transport. Culture in serum-deficient
      medium also produces rapid inhibition of growth at low cell density, but these
      cultures exhibit a markedly decreased rate of deoxyglucose uptake.

PMID- 4365701
TI  - Guanosine 3':5'-cyclic monophosphate and the action of insulin and acetylcholine.
AB  - Low concentrations of insulin (120 muunits/ml) and of carbamylcholine (1 muM)
      increase cyclic GMP content in isolated fat cells by 350%. The maximal amount of
      cyclic GMP, achieved within 2 min after addition of insulin or carbamylcholine,
      falls rapidly for insulin and much more slowly for carbamylcholine. 10 pM
      Acetylcholine can also augment the content of fat-cell cyclic GMP, but by 5 min
      (37 degrees ) the amount falls to that of unstimulated cells. Atropine abolishes
      the effects of carbamylcholine and acetylcholine but does not modify that of
      insulin, indicating that the ability of insulin to regulate cyclic GMP levels is
      not mediated by cholinergic receptors. Insulin and carbamylcholine increase the
      concentration of cyclic GMP in rat-liver slices by 400%; the effects of both
      agents occur rapidly and are relatively transient. Insulin does not alter cyclic
      GMP concentrations in purified human peripheral lymphocytes or in rat-spleen
      lymphocytes, cells which possess few insulin receptors and which are insensitive
      to the metabolic effects of the hormone. Carbamylcholine, however, causes a
      substantial increase in the cyclic GMP content of these lymphocytes. The data
      support the view that close and reciprocal relationships may exist between the
      concentrations and actions of cyclic AMP and cyclic GMP, as well as between the
      enzymes responsible for biosynthesis and degradation of these nucleotides.

PMID- 4365702
TI  - Effect of ADP-induced shape change on incorporation of 32P into platelet
      phosphatidic acid and mono-, di- and triphosphatidyl inositol.

PMID- 4365703
TI  - [Treatment of primary lipoproteinemia type IIa and IIb with highly purified
      dextro-thyroxine (D-T4). Controlled study in ambulant conditions].

PMID- 4365705
TI  - Letter: Status report: feline leukemia.

PMID- 4365704
TI  - [Hypercalciuria--nephrocalcinosis-- and calcium calculi of the kidney.
      Differential diagnosis and clinical aspects of pathological renal calcium
      transport].

PMID- 4365706
TI  - [Role of inhibitory interaction in the formation of an impulse reaction of the
      central auditory neurons to an acoustic signal].

PMID- 4365707
TI  - [Passive haemagglutination: a sensitive alpha1-foetoprotein assay (author's
      transl)].

PMID- 4365708
TI  - [The ultrastructure of lattice dystrophy of the cornea (author's transl)].

PMID- 4365709
TI  - The biogenesis of mitochondria in Neurospora crassa: ultrastructural changes
      induced by nutrients.

PMID- 4365710
TI  - Conjunctivitis. Differential diagnosis and treatment.

PMID- 4365711
TI  - Physical compatibility and chemical stability of cephapirin sodium in combination
      with antibiotics and large-volume parenteral solutions. I.

PMID- 4365712
TI  - An ultrastructural study of the first cleavage of Xenopus embryos.

PMID- 4365713
TI  - Homology between human breast tumour RNA and mouse mammary tumour virus genome.

PMID- 4365714
TI  - Invisible glomus tumor.

PMID- 4365715
TI  - Fine structure and cytochemistry of testicular cells in men treated with
      testosterone propionate.

PMID- 4365716
TI  - Tumours of the nervous system in the African in Eritrea (Ethiopia).

PMID- 4365717
TI  - Serological characterization of the three major proteins of vesicular stomatitis
      virus.
AB  - The three major proteins of vesicular stomatitis virus-Indiana, glycoprotein (G),
      nucleoprotein (N), and membrane protein (M), were isolated and characterized by
      means of specific monocomponent antisera. G, N, and M proteins are distinct,
      nonrelated antigens with specific serological properties. The G protein is the
      only antigen inducing the formation of virus-neutralizing antibodies and was
      shown to confer immunity to mice. Specific complement-fixing and precipitating
      activity was demonstrated for each of the three antisera. The future use of
      isolated rhabdovirus components and of monospecific antisera is considered for
      therapeutic and diagnostic purposes as well as for virus strain differentiation
      and classification work.

PMID- 4365718
TI  - Inhibition of herpes simplex virus type 2 replication by thymidine.
AB  - Replication of herpes simplex virus type 2 (HSV-2) was impeded in KB cells which
      were blocked in their capacity to synthesize DNA by 2 mM thymidine (TdR). The
      degree of inhibition was dependent upon the concentration of TdR. In marked
      contrast, HSV-1 is able to replicate under these conditions. The failure of HSV-2
      to replicate is probably due to the inhibition of viral DNA synthesis; there was
      a marked reduction in the rate of DNA synthesis as well as the total amount of
      HSV-2 DNA made in the presence of 2 mM TdR. We postulated that the effect of TdR
      on viral replication occurs at the level of ribonucleotide reductase in a manner
      similar to KB cells. However, unlike KB cells, an altered ribonucleotide
      reductase activity, highly resistant to thymidine triphosphate inhibition, was
      found in extracts of HSV-2-infected KB cells. This activity was present in HSV-2
      infected cells incubated in the presence or absence of TdR. Ribonucleotide
      reductase activity in extracts of HSV-1-infected KB cells showed a similar
      resistance to thymidine triphosphate inhibition. These results suggest that the
      effect of TdR on HSV-2 replication occurs at a stage of DNA synthesis other than
      reduction of cytidine nucleotides to deoxycytidine nucleotides.

PMID- 4365719
TI  - Presence in leukemic cells of avian myeloblastosis virus-specific DNA sequences
      absent in normal chicken cells.
AB  - (3)H-labeled 35S RNA from purified avian myeloblastosis virus (AMV) was
      exhaustively hybridized with an excess of normal chicken DNA to remove all viral
      RNA sequences which are complementary to DNA from uninfected cells. The [(3)H]RNA
      which failed to hybridize was isolated by hydroxylapatite column chromatography
      which separates DNA-RNA hybrids from single-stranded [(3)H]RNA. The residual RNA
      hybridized to leukemic chicken DNA but did not rehybridize with normal chicken
      DNA. This demonstrates conclusively that DNA from AMV-induced leukemic cells
      contain viral-specific sequences which are absent in DNA from normal cells.

PMID- 4365720
TI  - The changing seborrheic keratosis.

PMID- 4365721
TI  - Colitis in mice with a high incidence of rectal prolapse.

PMID- 4365722
TI  - Quantitative studies on the migration and development of Taenia pisiformis larvae
      in laboratory rabbits.

PMID- 4365723
TI  - Bacterial diseases of bats: a review.

PMID- 4365724
TI  - Heart rate in caged rhesus monkeys (Macaca mulatta).

PMID- 4365725
TI  - A new technical approach for the study of endometrial regeneration in the rabbit.

PMID- 4365726
TI  - Comparative aspects of mastocytosis in man and animals with report of a case in a
      baboon.

PMID- 4365727
TI  - The thiolation, methylation, and formation of pseudouridine and dihydrouridine in
      tRNA of regenerating rat liver, human phytohemagglutinin stimulated lymphocytes,
      and Novikoff ascites cells.

PMID- 4365728
TI  - Interrelation of epithelial glycogen, cell proliferation and cellular migration
      with cyclic adenosine monophosphate in epithelial wound healing.

PMID- 4365729
TI  - Hyporeactivity of tissue cultures.

PMID- 4365730
TI  - Radioimmunoassay of insulin by the double antibody method. Evaluation of the
      techique in practice.

PMID- 4365731
TI  - [Cellular immune defect: an isolated immunocytic deficiency syndrome (author's
      transl)].

PMID- 4365732
TI  - A new indigogenic method for the light and electron microscopic demonstration of
      5'-nucleotide phosphodiesterases.

PMID- 4365733
TI  - Histochemical demonstration of xanthine dehydrogenase in the tissues of the
      domestic fowl.

PMID- 4365734
TI  - A mitochondrial iron protein with properties of a high-potential iron-sulfur
      protein.

PMID- 4365735
TI  - Unsubstituted agarose as an affinity matrix for isolation of NAD-dependent alpha
      glycerophosphate dehydrogenase from the trypanosomatid Crithidia fasciculata.

PMID- 4365736
TI  - Mobilization of iron from reticulocyte ghosts by cytoplasmic agents.

PMID- 4365737
TI  - Evaluation of mammography based upon correlation of specimen mammograms and
      histopathologic findings.

PMID- 4365738
TI  - Kinetics of Woodward's Reagent K hydrolysis and reaction with staphylococcal
      nuclease.

PMID- 4365739
TI  - Yeast glycogen synthetase in the glucose 6-phosphate-dependent form. I.
      Purification and properties.

PMID- 4365740
TI  - Myosin in cultured fibroblasts.

PMID- 4365741
TI  - The interaction of polypeptide components of human high density lipoprotein with
      sodium dodecyl sulfate.

PMID- 4365742
TI  - Comparison of surface membranes isolated from cultured murine neuroblastoma cells
      in the differentiated or undifferentiated state.

PMID- 4365743
TI  - Epinephrine and adrenocorticotropic hormone-stimulated magnesium accumulation in
      adipocytes and their plasma membranes.

PMID- 4365744
TI  - Proceedings: Rhodopsin and light-sensitive kinase activity of retinal outer
      segments.

PMID- 4365745
TI  - Childhood cancer: the national Wilm's tumor study. A progress report.

PMID- 4365746
TI  - Immediate inactivation of T7 coliphage treated by monofunctional alkylating
      agents.

PMID- 4365747
TI  - [Influence of different hormones on the evolution of embryonic chicken liver in
      organotypic culture].

PMID- 4365748
TI  - The association of adenovirus infection with disease of the intestinal tract.

PMID- 4365749
TI  - Rapid diagnostic techniques in clinical virology.

PMID- 4365750
TI  - Immunoglobulins in virus disease.

PMID- 4365751
TI  - [Intravital tellurium labeling of lysosomal storage organoids in exogenous
      lipoidosis].

PMID- 4365752
TI  - [Comparative study of the lipid fraction content and incorporation of P32
      orthophosphate into individual phospholipids in experimental lung tumors and in
      normal lungs of mice].

PMID- 4365753
TI  - [Action of insulin and oxytocin on the lipolytic activity of rat adipose tissue].

PMID- 4365754
TI  - [Phospholipid makeup of the sarcoplasmic reticulum of normal and dystrophic
      muscular tissue in mice].

PMID- 4365755
TI  - [Pathogenetic role of kinins in allergic lesion of the myocardium].

PMID- 4365756
TI  - [Role of viruses in cardiac pathology].

PMID- 4365757
TI  - Immunofluorescence evidence for the distribution of cyclic AMP in cells and cell
      masses of the cellular slime molds.
AB  - With immunofluorescent techniques it has been possible to show that bound cyclic
      AMP is uniformly distributed in the nucleus and cytoplasm of a number of species
      of cellular slime molds. One species (which does not respond to cyclic AMP as an
      acrasin) is an exception and has its cyclic AMP concentrated in the nucleus
      during the feeding and aggregation stage. In cell masses of Dictyostelium
      discoideum that show early signs of differentiation the anterior, prestalk cells
      contain more cyclic AMP than the posterior, prespore cells.

PMID- 4365758
TI  - Effects of epinephrine, adrenocorticotrophic hormone, and theophylline on
      adenosine 3', 5'-monophosphate phosphodiesterase activity in fat cells.
AB  - When rat fat cells were incubated with ACTH, epinephrine, or theophylline for 2
      to 10 min, cyclic AMP phosphodiesterase (3':5'-cyclic-AMP 5'-nucleotidohydrolase,
      E.C. 3.1.4.17) activity (K(m) about 0.39 muM) in the 100,000 x g sediment
      fraction of homogenates was increased 35 to 50%. The effects of epinephrine and
      ACTH were concentration dependent and maximal increases were produced with
      concentrations similar to those that maximally stimulate lipolysis. Theophylline
      (0.5 mM) similarly increased phosphodiesterase activity but did not enhance the
      effects of maximally effective concentrations of the hormones. The changes in
      phosphodiesterase activity following addition of ACTH or theophylline paralleled
      changes in cell cyclic AMP content; both reached a maximum within 5 min and then
      declined, approaching basal levels after 20 or 30 min. The increased
      phosphodiesterase activity in cells incubated for 5 min with epinephrine reverted
      to basal levels within 2.5 min after the addition of propranolol. Our data are
      consistent with the view that there is a component of the fat-cell
      phosphodiesterase, perhaps localized in the plasma membrane, whose activity can
      be acutely modified by the concentration of its substrate, cyclic AMP. As
      previously reported (J. Biol. Chem.248, 7164-7170, 1973), exposure of fat cells
      to insulin increases the activity of a low K(m) phosphodiesterase also localized
      in the 100,000 x g sediment fraction of fat cell homogenates. In the presence of
      insulin, however, phosphodiesterase remained elevated for at least 40 min and
      there was no significant change in fat-cell cyclic AMP content. When
      phosphodiesterase activity was elevated and cyclic AMP content maintained at a
      high level by incubation of cells with ACTH plus theophylline, insulin produced a
      further increase in enzyme activity. Whether or not insulin and ACTH (or
      epinephrine or theophylline) affect the same phosphodiesterase, there seems
      little doubt that the underlying mechanisms are different.

PMID- 4365759
TI  - Immune lysis of liposomes and erythrocyte ghosts loaded with spin label.
AB  - It is shown that the paramagnetic resonance of spin labels offers a convenient
      technique for monitoring the complement-mediated immune lysis of erythrocyte
      ghosts, and sensitized phospholipid liposomes. The ghosts or liposomes are loaded
      with a concentrated solution of a water-soluble, membrane-impermeable spin label,
      so that there is a strong exchange broadening of the paramagnetic resonance
      signal due to labels enclosed within the liposomes or ghosts. Complement-mediated
      lysis releases the labels into a dilute solution, where a relatively sharp and
      intense paramagnetic resonance signal is detected. AN UNANTICIPATED RESULT IS
      ALSO REPORTED: this is the augmentation of release of spin label from loaded
      ghosts sensitized with egg albumin, in the presence of antibody against egg
      albumin, complement, and egg albumin in solution, over and above the release in
      the absence of egg albumin in solution. Comparison with complement fixation
      suggests that the augmentation of lysis is effected by crosslinking of immune
      complexes with the cell membrane.

PMID- 4365760
TI  - Characterization and substrate specificity of a protein carboxymethylase in the
      pituitary gland.
AB  - Protein carboxymethylase, an enzyme capable of methylating proteins and
      polypeptides, was purified from bovine pituitary. The anterior pituitary
      hormones, luteinizing hormone, follicle-stimulating hormone, adrenocorticotropic
      hormone, growth hormone, thyroid-stimulating hormone, and prolactin, were found
      to be substrates for this enzyme. The posterior pituitary hormones, oxytocin and
      vasopressin, did not serve as substrates. With luteinizing hormone as the
      substrate, protein carboxymethylase had a pH optimum near pH 5.5. A limiting K(m)
      of 1.47 muM for S-adenosyl-L-methionine was obtained with luteinizing hormone as
      the methyl acceptor. Possible roles of this enzyme in the posterior and anterior
      pituitary are discussed.

PMID- 4365761
TI  - Angiotensin-converting enzyme from rabbit pulmonary particles.
AB  - Angiotensin-converting enzyme has been solubilized from rabbit pulmonary
      particles and purified to homogeneity. The molecular weight of the native enzyme
      was estimated to be about 136,000 by glycerol gradient centrifugation, and a
      value of 140,000 was obtained for the reduced denatured protein by disc-gel
      electrophoresis in the presence of sodium dodecyl sulfate and 2-mercaptoethanol.
      The enzyme was found to be a glycoprotein with carbohydrate accounting for
      approximately 16% of its dry weight. The major sugar residues were identified as
      galactose, N-acetylglucosamine, and mannose, with smaller amounts of fucose and
      sialic acid. The homogeneous enzyme catalyzed the release of His-Leu from the
      COOH-terminus of angiotensin I and of Phe-Arg and Ser-Pro from that of
      bradykinin.

PMID- 4365762
TI  - Interspecific recombination of mitochondrial DNA molecules in hybrid somatic
      cells.
AB  - The mitochondrial DNA (mtDNA) in rodent-human hybrid somatic cells was studied in
      strains that contain nucleotide sequences from both parental mtDNAs. A test for
      linkage of rodent to human mtDNA was devised on the basis of the density and
      sequence differences between these DNAs. When a mixture of rodent and human
      mtDNAs was banded in a CsCl gradient and each fraction hybridized with a mixture
      of complementary [(3)H]RNA transcribed from human mtDNA and complementary
      [(32)P]RNA transcribed from rodent mtDNA, each DNA was detected as a distinct and
      separate band at its expected density by specific hybridization with its
      complementary RNA. In some of the hybrid cell strains, the mtDNA sequences
      derived from the two species did not separate in the CsCl gradients. This result
      is interpreted as evidence for linkage between sequences from the two parental
      mtDNAs. While the exact nature of the linkage and the structure of the molecules
      containing both types of sequences are not known, the evidence supports the
      conclusion that the linkage is realized by a covalent bond. An event leading to
      the covalent bonding of these different sequences may be described as
      recombination. Among 18 hybrid cell strains examined, 13 contained large
      proportions of recombinant molecules. These molecules were found in both mouse
      human and rat-human strains, and in strains containing more human or more rodent
      mtDNA sequences.

PMID- 4365763
TI  - Estrogen-related increases in uterine guanosine 3':5'-cyclic momophosphate
      levels.
AB  - Endogenous uterine cyclic GMP and cyclic AMP concentrations were monitored at
      each stage of the estrus cycle; cyclic GMP concentrations were found to be
      highest and cyclic AMP concentrations lowest during proestrus when plasma
      estrogen levels have been shown to be maximal. After administration of estradiol
      17beta or diethylstilbestrol, the concentrations of uterine cyclic GMP in
      ovariectomized rats underwent a progressive and significant elevation and the
      levels of cyclic AMP declined significantly below control values when near
      maximal accumulation of tissue cyclic GMP was achieved. The increase in uterine
      cyclic GMP concentrations produced by estradiol benzoate administration was
      prevented when progesterone and the estrogen were co-administered. These results
      raise the possibility that an enhanced cellular accumulation of cyclic GMP may be
      involved in the expression of some of the actions of estrogen in uterine tissue.

PMID- 4365764
TI  - Cyclic-AMP-controlled oscillations in suspended Dictyostelium cells: their
      relation to morphogenetic cell interactions.
AB  - Periodic spikes of decreased optical density were recorded in cell suspensions of
      Dictyostelium discoideum. Spike formation as well as changes in the redox state
      of cytochrome b are facultatively and independently coupled to an oscillating
      system which is under developmental control and presumably underlies signal
      transmission in aggregating cells. Cyclic AMP triggers a double response, the
      slow component resembling the spikes formed during spontaneous oscillations. The
      fast component shows characteristics of the chemotactic response to cyclic AMP.
      The receptor system is suggested to sense changes of cyclic AMP concentration in
      time. Cyclic AMP pulses interact with the oscillating system, resulting in phase
      shift or suppression of spike formation, and in the induction of oscillations in
      an early stage of development before the onset of spontaneous oscillations.
      Continuous flow application of cyclic AMP does not change frequency up to flow
      rates which extinguish oscillations.

PMID- 4365765
TI  - Simultaneous administration of dichlorvos anthelmintic and modified live virus
      vaccines to puppies.

PMID- 4365766
TI  - [Therapeutics in 1973].

PMID- 4365767
TI  - [Sensitivity of 150 Pseudomonas strains determined by the bouillon dilution
      method and the Kirby-Bauer method].

PMID- 4365769
TI  - [Experimental treatment of burns by hypodermic drug administration].

PMID- 4365768
TI  - A study of serum vitamin B12 in various peripheral neuropathies.

PMID- 4365770
TI  - [Activity of certain enzymes (AspAT, AlaAT, nonspecific ChE, CytO, LDH) and LDH
      isoenzymes in the serum, myocardium and liver in experimental myocardial
      infarct].

PMID- 4365771
TI  - [Pituitary apoplexy].

PMID- 4365772
TI  - Third F. Raymond Keating, Jr., Memorial Symposium--parathyroid hormone,
      calcitonin and vitamin D: clinical considerations. II. Vitamin D--1973.

PMID- 4365773
TI  - Rickets and the pathogenesis of impaired tubular transport of phosphate and other
      solutes.

PMID- 4365774
TI  - The physiologic significance of plasma transport of vitamin D and metabolites.

PMID- 4365775
TI  - Circulating 25-hydroxyvitamin D in man.

PMID- 4365776
TI  - Intrauterine infection and cord immunoglobulin M. 3. Serological analysis of
      infants with elevated cord serum immunoglobulin M.
AB  - The presence of antibodies to rubella, cytomegalovirus and Toxoplasma gondii was
      determined at birth and at 6 months of age in a group of 147 infants with cord
      serum IgM levels >/= 19.0 mg/dl and in 92 control infants. Maternal syphilis
      serology was determined in both groups as well. No significant differences in the
      prevalence or levels of antibodies to these pathogens were found between the two
      groups which might have led to the diagnosis of unsuspected intrauterine
      infection. Persistence of antibodies to 6 months of age was similar in the two
      groups, indicating that this is not a useful index of intrauterine
      infection.ANALYSIS OF THE RESULTS YIELDED THE FOLLOWING DATA ON THE PREVALENCE OF
      ANTIBODIES TO THE PATHOGENS STUDIED: rubella virus, 90 and 75% seropositivity at
      birth and 6 months respectively; cytomegalovirus, 65 and 35%; and Toxoplasma
      gondii, 33% seropositivity at birth.

PMID- 4365777
TI  - [Isocitrate lyase of Candida guilliermondii, strain H17. II. Regulation by
      selected intermediates of the tricarboxylic acid cycle and hexose catabolism].

PMID- 4365778
TI  - Transport of peroxidase in flounder kidney tubules studied by electron microscope
      histochemistry.

PMID- 4365779
TI  - Sedative or tranquillizer? A comparison of the hypnotic effects of
      chlordiazepoxide and amylobarbitone sodium.

PMID- 4365780
TI  - Nuclear gene dosage effects on mitochondrial mass and DNA.
AB  - In order to assess the effect of nuclear gene dosage on the regulation of
      mitochondria we have studied serial sections of a set of isogenic haploid and
      diploid cells of Saccharomyces cerevisiae, growing exponentially in the absence
      of catabolite repression, and determined the amount of mitochondrial DNA per
      cell. Mitochondria accounted for 14% of the cytoplasmic and 12% of the total
      cellular volume in all cells examined regardless of their ploidy or their
      apparent stage in the cell cycle. The mean number of mitochondria per cell was 22
      in the diploid and 10 in the haploids. The volume distribution appeared unimodal
      and identical in haploids and diploids. The mitochondrial DNA accounted for 12.6
      +/- 1.2% and 13.5 +/- 1.3% of the total cellular DNA in the diploid and haploid
      populations, respectively. These values correspond to 3.6 x 10(-15) g, 2.2 x
      10(9) daltons, or 44 genomes (50 x 10(6) daltons each) per haploid and twice that
      per diploid cell. On this basis, the average mitochondrion in these cells
      contains four mitochondrial genomes in both the haploid and the diploid.

PMID- 4365781
TI  - Lysosomal packaging in differentiating and degenerating anuran lateral motor
      column neurons.
AB  - The role of the Golgi apparatus and the Golgi-endoplasmic reticulum-lysosome
      complex (GERL) in the genesis of lysosomes was examined in differentiating and
      degenerating motor neurons of anuran larvae. Acid phosphatase, aryl sulfatase,
      and thiolacetic acid esterase were utilized as marker enzymes for the lysosomal
      system, while nucleoside diphosphatase and thiamine pyrophosphatase labeled the
      inner saccule(s) of the Golgi apparatus. Reduced osmium tetroxide was routinely
      deposited in the outer Golgi saccule regardless of the state of neuronal
      maturation. In all young neurons, the disposition of acid hydrolase reaction
      product paralleled the formation of GERL, with no lytic activity in the Golgi
      apparatus per se. Hypertrophy of the Golgi apparatus and GERL was observed in the
      early phases of degeneration, and both organelles apparently exhibit extensive
      hydrolytic activity. Dense bodies, autophagic vacuoles, and primary lysosomes
      were found arising from GERL, while the Golgi apparatus may produce primary
      lysosomal granules during regression. On the other hand, in differentiating
      neurons, hydrolytic activity was restricted to GERL and an occasional dense body
      and autophagic vacuole. These studies illustrate a parallelism between the
      development of GERL and genesis of primary and secondary lysosomes during
      neuronal cytodifferentiation, and implicate GERL and possibly the Golgi apparatus
      in lysosomal packaging in degenerating neurons.

PMID- 4365782
TI  - [Etiology and pathogenesis of hypertension].

PMID- 4365783
TI  - [Cardiovascular forms of arterial hypertension].

PMID- 4365784
TI  - [Primary hypo- and hyperreninism].

PMID- 4365785
TI  - [A simple and rapid technic for triglyceride determination].

PMID- 4365786
TI  - [Determination of 17-alpha hydroxyprogesterone in plasma using competitive
      protein binding].

PMID- 4365787
TI  - Quinoline derivatives as antiallergy agents.

PMID- 4365788
TI  - Thymidine 5' variants as inhibitors of thymidylate kinase.

PMID- 4365789
TI  - Morphology of mesenchymal elements of normal artery, fatty streaks, and plaques.

PMID- 4365790
TI  - Studies of primate arterial smooth muscle cells in relation to atherosclerosis.

PMID- 4365791
TI  - Changes in plasma levels of estrone sulfate and estrone in the pregnant ewe
      around parturition.

PMID- 4365792
TI  - Fatal herpes hepatitis associated with pemphigus vulgaris and steroids in an
      adult.

PMID- 4365793
TI  - [Electron microscope studies of synovial tissue in juvenile rheumatoid
      arthritis].

PMID- 4365794
TI  - Thiamine diphosphate content of liver mitochondria of the pregnant and developing
      rat.

PMID- 4365795
TI  - [Arteriographic exploration of secondary liver cancers. Value of arterial
      injection of iodolipids].

PMID- 4365796
TI  - [Myocardial infarction in general medicine practice. Study of a continuous series
      of 174 cases].

PMID- 4365797
TI  - [Pulmonary diseases in subjects over 70 years old. Effect on respiratory
      function].

PMID- 4365798
TI  - Dugbe virus: a tick-borne arbovirus from Nigeria.

PMID- 4365799
TI  - Partial separation of Sendai virus-fused lymphocytes by velocity sedimentation.

PMID- 4365800
TI  - [Neutron activation analysis of the trace elements cobalt, iron, rubidium,
      selenium, zinc, chromium, silver, cesium, antimony and scandium in surgical
      specimens of human brain tumors. 1].

PMID- 4365801
TI  - Riboflavin deficiency and galactose metabolism in human subjects.

PMID- 4365802
TI  - Microsomal Na+-stimulated NADH-cytochrome c reductase: could it be involved in
      sodium transport?

PMID- 4365803
TI  - Intracellular concentration of inorganic pyrophosphate in the cells of
      Escherichia coli: a method for its determination.

PMID- 4365804
TI  - A microassay for guanosine 3',5'-monophosphate phosphodiesterase activity.

PMID- 4365805
TI  - Assay of cyclic AMP by an isotope dilution test with binding protein.

PMID- 4365806
TI  - Coprecipitation of ATP with potassium perchlorate: the effect of the firefly
      enzyme assay of ATP in tissue and blood.

PMID- 4365807
TI  - Separation and automated analysis of phosphorylated metabolic intermediates.

PMID- 4365808
TI  - Langerhans cells in a bronchiolar-alveolar tumour of lung.

PMID- 4365809
TI  - A statistical analysis of the release of acetylcholine at newly formed synapses
      in striated muscle.
AB  - 1. A statistical analysis has been made of the changes in the binomial parameters
      n and p during transmitter release from motor-nerve terminals when synapses are
      forming in either regenerating or reinnervated mammalian muscle.2. The amplitude
      frequency distribution of e.p.p.s evoked by a single impulse was well predicted
      by binomial statistics at all junctions analysed allowing values of n and p to be
      determined. At most of these junctions, p > 0.5 and Poisson statistics did not
      predict the observed distributions at all.3. During the changes in quantal
      content which occur during short trains of impulses or during continual
      stimulation over minutes, no significant change in p was detected. Changes in
      quantal content of the e.p.p. were therefore determined by n.

PMID- 4365810
TI  - [Regulation of hexuronate metabolism in Escherichia coli K12. Kinetics of enzyme
      induction of the hexuronate system].

PMID- 4365812
TI  - 28-S RNA from Xenopus laevis contains a sequence of three adjacent 2'-O
      methylations.

PMID- 4365811
TI  - Sulfhydryl group reactivity of D-galactose dehydrogenases from Pseudomonas
      saccharophila.

PMID- 4365813
TI  - Characterization of blood-group-H-active ceramide tetrasaccharide from hog
      stomach mucosa.

PMID- 4365814
TI  - Aspiration biopsy cytology. I. Cytology of supradiaphragmatic organs. 8 Lungs.

PMID- 4365816
TI  - Proceedings: Plasma levels of amino acids and glucagon in patients with
      pancreatic glucagonomas.

PMID- 4365815
TI  - [The genesis of hyperuricemia in patients with essential hypertension (author's
      transl)].

PMID- 4365817
TI  - Fine-structural observations on the gill filaments of the fresh-water crayfish,
      Astacus pallipes Lereboullet.

PMID- 4365818
TI  - Editorial: Vitamin D, the kidney and calcium homeostasis.

PMID- 4365819
TI  - The effect of exogenous angiotensin on superficial and deep glomeruli in the rat
      kidney.

PMID- 4365820
TI  - An evaluation of the contribution of cholinergic mechanism to thirst.

PMID- 4365821
TI  - Centrally mediated effects of angiotensin II in the unanesthetized rat.

PMID- 4365822
TI  - [Determination of certain sterols--products of vitamin D3 synthesis--by means of
      thin-layer chromatography].

PMID- 4365823
TI  - [Viral origin of certain cases of chronic intrahepatic cholestasis: a case of
      hypercholostatic and hyperlipidemic jaundice evolving towards a chronic
      condition].

PMID- 4365824
TI  - [Curative treatment of Duhring-Brocq disease using BCG vaccination (part 2)].

PMID- 4365825
TI  - [Aneurysmal sciatica or the pulsing buttock syndrome].

PMID- 4365826
TI  - [Central form of Recklinhausen's disease with neurinomas and multiple meningiomas
      and associated gliomatosis].

PMID- 4365828
TI  - [Mazarini and the doctors].

PMID- 4365827
TI  - [Crohn's disease of the colon in patients with pulmonary tuberculosis].

PMID- 4365829
TI  - [History of bezoars. From legendary belief to human pathology].

PMID- 4365830
TI  - [Diagnosis and treatment of diseases of the parotid (author's transl)].

PMID- 4365831
TI  - Studies on Coccidioides immitis. XVII: Morphology of the parasite in relationship
      with the host immunoallergic condition in the experimental infection of the
      guinea-pig.

PMID- 4365832
TI  - Occurrence of atypical lymphocytes following intravenous injection of Candida
      albicans in mice.

PMID- 4365833
TI  - Comparative treatment of hyperlipoproteinaemias in chimpanzees.

PMID- 4365834
TI  - [Myelography--its value in the diagnosis and treatment of prolapse of lumbar
      intervertebral disk (author's transl)].

PMID- 4365835
TI  - [The family of a patient with galactokinase-defect 2nd communication (author's
      transl)].

PMID- 4365836
TI  - Glycosylation of beta-lipoprotein and the possible role of choline derivatives.

PMID- 4365837
TI  - Urinary excretion of cyclic AMP by cold-acclimated rats.

PMID- 4365838
TI  - Enzymatic dehydrogenation of testosterone coupled to pyruvate reduction in a two
      phase system.

PMID- 4365839
TI  - Nucleophilic addition at the photoexcited flavin cation: synthesis and properties
      of 6- and 9-hydroxy-flavocoenzyme chromophores.

PMID- 4365840
TI  - Identification and properties of new flavins in electron-transferring
      flavoprotein from Peptostreptococcus elsdenii and pig-liver glycolate oxidase.

PMID- 4365841
TI  - Regulation of myocardial contraction.

PMID- 4365842
TI  - Free fatty acids and the ischaemic myocardium.

PMID- 4365843
TI  - Regulatory role of adenyl cyclase and cyclic AMP.

PMID- 4365844
TI  - Lymphocytes in infectious mononucleosis. Properties of atypical cells and origin
      on the lymphoblastoid lines.

PMID- 4365845
TI  - [Ultrastructural detection of leucine aminopeptidases by lead chelation].

PMID- 4365846
TI  - Urea-cycle enzymes in normal liver and in patients with alcoholic hepatitis.

PMID- 4365847
TI  - [Participation of histiocytes and smooth muscle fibers in the formation of
      Aschoff's nodules].

PMID- 4365848
TI  - Effect of onion ingestion on serum triglyceride, betalipoprotein-cholesterol and
      phospholipids in alimentary lipaemia.

PMID- 4365849
TI  - [Dysfunction of phagocytosis with special reference to chronic granulomatous
      disease].

PMID- 4365850
TI  - [Examination of yolk extracts within the scope of serological research on the
      incidence of poultry diseases].

PMID- 4365852
TI  - Influence of prostaglandin E1 on cyclic 3',5'-AMP levels and glycosaminoglycan
      secretion of fibroblasts cultured in vitro.

PMID- 4365851
TI  - Coeliac disease. Electron microscopy of jejunal mucosa.

PMID- 4365853
TI  - Influence of antiphlogistic drugs on prostaglandin E1 stimulated cyclic 3',5'-AMP
      levels and glycosaminoglycan synthesis in fibroblast tissue cultures.

PMID- 4365854
TI  - Effects of prostaglandin synthesis inhibitors on angiotensin tachyphylaxis in the
      isolated coeliac and mesenteric arteries of the rabbit.

PMID- 4365855
TI  - Studies on human cytomegalovirus strain variations by membrane-fluorescence.

PMID- 4365856
TI  - Cytomegalovirus infection after lumbosacral fusion. A case report.

PMID- 4365857
TI  - [The Renin-Angiotensin-Aldosterone system in kidney diseases].

PMID- 4365858
TI  - [Epidemiology].

PMID- 4365859
TI  - Editorial: Sex and alcohol.

PMID- 4365860
TI  - Astrocytosis without globules in infant cerebral white matter. An epidemiologic
      study.

PMID- 4365861
TI  - [A technic to obtain ultrathin longitudinal sections of fungal mycelian hyphae
      for electron microscopy].

PMID- 4365862
TI  - Vitreoretinal juncture--simple epiretinal membranes.

PMID- 4365863
TI  - Effect of dipyridamole on retinal embolism associated with cardiopulmonary bypass
      surgery in the dog.

PMID- 4365865
TI  - Serum prolactin levels during ovulatory menstrual cycle and menstrual disorders
      in women.

PMID- 4365864
TI  - Rubella and cytomegalovirus. Current concepts of congenital and acquired
      infection.

PMID- 4365866
TI  - A human papovavirus (B.K.), biological properties and seroepidemiology.

PMID- 4365868
TI  - Plasma renin and angiotensin I converting enzyme activity in anaphylactic shock.

PMID- 4365867
TI  - Adynamic ileus, its pathogenesis and treatment.

PMID- 4365869
TI  - [Enzyme convertor of angiotensin].

PMID- 4365870
TI  - [Polygraph studies of sleep in cerebrovascular ischemic disease].

PMID- 4365872
TI  - [Polygraph study of sleep in nocturnal ambulatory automatism].

PMID- 4365871
TI  - Abnormal reflexes in the "stiff-man" syndrome.

PMID- 4365873
TI  - A roentgenologic study of epiphyseal union around elbow, wrist and knee joints
      and the pelvis in boys and girls of Uttar Pradesh.

PMID- 4365874
TI  - [Histochemical changes in pharyngeal tonsils in small children with tonsillitis].

PMID- 4365875
TI  - [Influence of high altitude adaptation on the metabolic response following
      administration of adrenocorticotropic hormone and after hypoxia load in the
      altitude of 6000 m above sea level].

PMID- 4365876
TI  - [Alcohol-induced chylomicronemia in type IV hyperlipoproteinemia].

PMID- 4365877
TI  - [Primary carcinoma of the small intestine].

PMID- 4365878
TI  - [Studies on development of the phycomycete Allomyces arbuscula. I. Effects of
      inhibitors of protein and nucleic acid synthesis on differentiation of gametangia
      (author's transl)].

PMID- 4365879
TI  - Guanidine inhibition of poliovirus growth. Partial elimination by protease
      antagonists and low temperature.

PMID- 4365880
TI  - Studies on beta-galactosidase activity in Vibrio El Tor.

PMID- 4365881
TI  - [Polyphosphate metabolic enzymes in the developmental process of
      Propionibacterium shermanii normally and in the presence of polymyxin M].

PMID- 4365882
TI  - [Tumor lipids. The positional distribution of fatty acids in rat liver
      glycerophospholipids and in hepatoma-27].

PMID- 4365883
TI  - [Action of different proline structural analogs on the synthesis of proteins in
      the cartilaginous tissue of chick embryos].

PMID- 4365884
TI  - Biochemical studies on sulfate-ruducing bacteria. 8. Sulfite reductase from
      Desulfovibrio vulgaris--mechanism of trithionate, thiosulfate, and sulfide
      formation and enzymatic properties.

PMID- 4365885
TI  - The activity of adenylate cyclase, phosphodiesterase and protein kinase in the
      adenohypophyses of rats treated by chronic administration of estrogens and acute
      application of thyroxine in vivo.

PMID- 4365886
TI  - The response of adipose tissue to lipid mobilizing hormones in postnatally under-
      and overnourished rats.

PMID- 4365887
TI  - Two types of insulin receptors mediating opposite effects on cyclic-amp in fat
      cells of the rat.

PMID- 4365888
TI  - Gastric HCO3-stimulated ATPase: evidence against its microsomal localization in
      rat fundus mucosa.

PMID- 4365889
TI  - Effect of insulin on the phosphorylation of adipose tissue protein.

PMID- 4365890
TI  - Testosterone-estradiol-binding globulin of human plasma: denaturation and
      protection.

PMID- 4365891
TI  - Purification of Clostridium perfringens phospholipase C (alpha-toxin) by affinity
      chromatography on agarose-linked egg-yolk lipoprotein.

PMID- 4365892
TI  - Synthetic analogs of the active sites of iron-sulfur proteins. 8. Some electronic
      properties of (Fe4S4(SR)4)3-, analogs of reduced bacterial ferredoxins.

PMID- 4365894
TI  - The influence of 2,3 diphosphoglycerate on the Bohr effect of sulfhemoglobin.

PMID- 4365893
TI  - A possible mechanism for the stimulation of Krebs cycle activity by ACTH in
      isolated rat adrenal cells.

PMID- 4365895
TI  - Peptidase activity of carrier proteins used in radioimmunoassays.

PMID- 4365896
TI  - Pathomorphologic and histochemical changes in the liver during hemodilution.

PMID- 4365897
TI  - Regulation of glycogen metabolism in acute uremic hearts.

PMID- 4365898
TI  - Catecholamine metabolism in health and disease.

PMID- 4365899
TI  - Biochemical genetics of bacterial sporulation. V. Fine structure analysis of two
      sporulation mutants of B. subtilis derepressed for late functions.

PMID- 4365900
TI  - Saponin adjuvants. 3. Isolation of a substance from Quillaja saponaria Molina
      with adjuvant activity in food-and-mouth disease vaccines.

PMID- 4365901
TI  - The development of double-seeded and mixed cell culture systems for use in
      diagnostic virology.

PMID- 4365902
TI  - Replication and plaque formation of mouse hepatitis virus (MHV-2) in mouse cell
      line DBT culture.

PMID- 4365903
TI  - Effect of morphinization on in vitro incorporation of labelled precursors into
      adrenal protein and nucleic acids in rats.

PMID- 4365904
TI  - Adrenergic mechanism in Tetrahymena. 3. Cyclic adenosine 3', 5'-monophosphate and
      cell proliferation.

PMID- 4365905
TI  - [What significance for the etiology and pathogenesis of rheumatoid arthritis
      have: b) infectious agents].

PMID- 4365906
TI  - Differentiation between early and late membrane antigen on human lymphoblastoid
      cell lines infected with Epstein-Barr virus. I. Immunofluorescence.

PMID- 4365907
TI  - Presence and transmission of mammary tumor virus and leukemia virus in the BALB
      cfRIII mouse.

PMID- 4365908
TI  - Latent infection and malignant lymphoma in marmosets (Callithrix jacchus) after
      infection with two oncogenic herpesviruses from primates.

PMID- 4365909
TI  - Pancreatic islet cell tumors in domestic animals. Data from 11 colleges of
      veterinary medicine in the United States and Canada.

PMID- 4365910
TI  - Variation in quantitative expression of Forssman antigen on virus-transformed
      hamster cells.

PMID- 4365911
TI  - Zinc intake and growth of a transplanted hepatoma induced by 3'-methyl-4
      dimethylaminoazobenzene in rats.

PMID- 4365912
TI  - Elevated cyclic AMP levels in human breast-cancer tissue.

PMID- 4365913
TI  - Acute cerebral infarction and hypotension: an ultrastructural study.

PMID- 4365914
TI  - The astrocyte response in experimental portal-systemic encephalopathy: an
      electron microscopic study.

PMID- 4365916
TI  - Electron-microscopic observations of scirrhous and mucin-producing carcinomas of
      the breast.

PMID- 4365915
TI  - Gliomas containing bone and cartilage.

PMID- 4365917
TI  - The nature of the circadian periodicity and suppressibility of immunoreactive
      ACTH levels in Addison's disease.

PMID- 4365918
TI  - Cyclic adenosine 3',5'-monophosphate concentration in plasma, adipose tissue and
      skeletal muscle in normal subjects and in patients with hyper- and
      hypothyroidism.

PMID- 4365919
TI  - Secretion of 16alpha-hydroxyprogesterone and other steroids by the adult human
      adrenal.

PMID- 4365920
TI  - Regulation of aldosterone in the syndrome of inappropriate antidiuretic hormone
      secretion (SIADH).

PMID- 4365921
TI  - Human adrenal tissue in vitro: steroidogenic properties.

PMID- 4365922
TI  - Cirrhosis and malignant hepatoma in alpha 1-antitrypsin deficiency.

PMID- 4365923
TI  - Respirable silica dust exposure of sandblasters and associated workers in steel
      fabrication yards.

PMID- 4365924
TI  - Effects of cigarette smoke components on bronchial clearance in the donkey.

PMID- 4365925
TI  - Wilm's tumour.

PMID- 4365926
TI  - Intranuclear inclusions in the lead-poisoned cultured kidney cell.

PMID- 4365927
TI  - Plasma MSH and cortisol levels in 567 patients with special reference to brain
      trauma.

PMID- 4365928
TI  - Cytophysiology and metabolism of pancreatic B-cell.

PMID- 4365929
TI  - Immediate effects of total visual deafferentation on single unit activity in the
      visual cortex of freely behaving cats. I. Tonic excitability changes.

PMID- 4365930
TI  - Immediate effects of total visual deafferentation on single unit activity in the
      visual cortex of freely behaving cats. II. Rhythmic EEG bursts and PGO waves.

PMID- 4365931
TI  - [Sleep patterns in cerebral palsied adult].

PMID- 4365932
TI  - Tumours of the orbit and the eye in Indonesia. A clincal-pathological
      correlation.

PMID- 4365933
TI  - Clostridium perfringens panophthalmitis.

PMID- 4365935
TI  - [Polymyxin B in the treatment of bacterial diarrhea in infants].

PMID- 4365936
TI  - [Abrikossoff's tumor].

PMID- 4365937
TI  - [Vertebral metastases in hepatocellular carcinoma].

PMID- 4365938
TI  - Methyl n-butyl ketone.

PMID- 4365939
TI  - Treatment of advanced primary liver carcinoma using intermittent intra-arterial
      nitrogen mustard.

PMID- 4365940
TI  - Genital herpes in guinea-pigs. An experimental model with Herpesvirus hominis.

PMID- 4365934
TI  - Metabolism and action of the hormone vitamin D. Its relation to diseases of
      calcium homeostasis.
AB  - Extensive experimental evidence has established a significant role of calciferol
      in the maintenance of normal calcium homeostasis. Present knowledge indicates
      that vitamin D(3) must first be converted to 25-OH-D(3) and then to
      1,25(OH)(2)D(3), the most active known form of the steroid. Many of the factors
      regulating the rate of production of this last steroid from its precurser have
      been evaluated, and the concept that vitamin D functions as a steroid hormone
      seems to be well established. Deranged action of calciferol, caused by impaired
      metabolism of the steroid or through altered sensitivity of target tissues, may
      be involved in the pathophysiology of several disease states with abnormal
      calcium metabolism. It is noted that liver disease, osteomalacia due to
      anticonvulsant therapy, chronic renal failure, hypophosphatemic rickets,
      hypoparathyroidism, hyperparathyroidism, sarcoidosis and idiopathic
      hypercalciuria have possible relation to alterations in metabolism or action of
      vitamin D. The future clinical availability of 1,25(OH)(2)D(3) and other analogs
      of this steroid may offer potential therapeutic benefit in the treatment of
      certain of the disease entities discussed.

PMID- 4365941
TI  - Simian virus 40 in a human cancer.

PMID- 4365942
TI  - Outline structure of cytochrome c3 and consideration of its properties.

PMID- 4365943
TI  - Congenital corneal clouding with abnormal systemic storage bodies: a new variant
      of mucolipidosis.

PMID- 4365944
TI  - Serologic responses to herpes simplex virus in rabbits: complement-requiring
      neutralizing, conventional neutralizing, and passive hemagglutinating antibodies.

PMID- 4365945
TI  - Pathogenesis of pulmonary cytomegalovirus infection in immunosuppressed mice.

PMID- 4365946
TI  - The effect of cholera enterotoxin on steroidogenesis in cultured adrenal tumor
      cells.

PMID- 4365947
TI  - Urinary tract infection and pyelonephritis due to Escherichia coli in dogs
      infected with canine adenovirus.

PMID- 4365949
TI  - Fecal excretion of cytomegalovirus in disseminated cytomegalic inclusion disease.

PMID- 4365948
TI  - Bacterial interference among strains of Staphylococcus aureus in man.

PMID- 4365950
TI  - Plasma proinsulin. Comparison of insulin specific protease and gel filtration
      assays.

PMID- 4365951
TI  - Relation of hypertension to changes in the arteries.

PMID- 4365952
TI  - Renin and aldosterone and the pathogenesis of hypertensive vascular damage.

PMID- 4365953
TI  - Plasma vitamin A and E levels in children with familial type II
      hyperlipoproteinemia during therapy with diet and cholestyramine resin.

PMID- 4365954
TI  - Vitamin A and glycosaminoglycan metabolism in rats.

PMID- 4365955
TI  - Influence of dietary protein on 6- and 9-desaturation of fatty acids in rats of
      different ages and in different seasons.

PMID- 4365956
TI  - Occurrence of Parkinson's disease in black patients at Charity Hospital in New
      Orleans.

PMID- 4365957
TI  - Lipid cerebrospinal fluid in a patient with cerebral hemorrhage.

PMID- 4365958
TI  - Sleep epilepsy: its pattern and prognosis.
AB  - In a series of 645 patients with epilepsy only 38 had attacks exclusively during
      sleep. A further 111 had attacks while waking and sleeping. The total number of
      patients whose epilepsy started with sleep attacks and who later developed
      attacks when waking increased with each successive year. The prognosis of sleep
      epilepsy is important in relation to the granting of driving licences.

PMID- 4365959
TI  - EB virus and the treatment of lymphomas.
AB  - The high incidence of EB virus infections (and possibly of other viruses) in
      patients with African lymphoma and, to a lesser extent, in patients with
      lymphosarcoma in the temperate zones, is thought to be due to its being a
      passenger virus which persists in the human body and, since it is lymphotropic,
      presents an opportunistic infection of proliferating lymphoid cells. The thesis
      is put forward that by entering the cell nucleus, the virus renders malignant
      lymphoid cells more vulnerable to cytotoxic drugs. Hence a deliberate policy of
      EB virus inoculation before starting chemotherapy might achieve a more rapid
      response and longer remissions in indigenous lymphomas of the temperate zones,
      and might possibly render drug-resistant cases once more drug-sensitive.

PMID- 4365960
TI  - Letter: Unsuspected cytomegalic mononucleosis.

PMID- 4365961
TI  - Letter: Mental changes in Parkinsonism.

PMID- 4365963
TI  - An unusual case of adenocarcinoma of the pancreas.

PMID- 4365962
TI  - Metronidazole and amebiasis.

PMID- 4365964
TI  - A histological, histochemical and biochemical study of the effect of the toxin of
      lupinosis on murine liver.

PMID- 4365965
TI  - [Vitamin D metabolism and rickets prevention].

PMID- 4365966
TI  - Plasma corticotrophin levels during insulin-hypoglycaemia: comparison of
      radioimmunoassay and cytochemical bioassay.

PMID- 4365967
TI  - DDT absorption and chylomicron transport in rat.

PMID- 4365968
TI  - Mass determination of lipids with automated thermogravimetric analytical
      procedure.

PMID- 4365970
TI  - [Chronic herpetic infection in a continuous culture of human lymphoblastoid
      cells].

PMID- 4365969
TI  - Radioimmunoassay for medroxyprogesterone acetate (Provera) using the 11alpha
      hydroxy succinyl conjugate.

PMID- 4365973
TI  - The cytochemical section assay for corticotrophin.

PMID- 4365971
TI  - [Use of an immunoelectronic method for studying the oncornavirus LPV and cells
      transformed by it].

PMID- 4365972
TI  - Ectopic hormone production by non-endocrine tumours.

PMID- 4365974
TI  - Validation of the redox cytochemical assay for corticotrophin.

PMID- 4365975
TI  - The redox bioassay technique for the direct assessment of pituitary
      adrenocorticotrophic activity in the rat.

PMID- 4365976
TI  - [Kinetics of the initial response of plasma corticoids to corticotropin
      administration].

PMID- 4365977
TI  - Massive fetal ascites, urethral atresia, and cytomegalic inclusion disease.

PMID- 4365978
TI  - Virus-like particles induced in guinea pig cells by 5-bromo-2'-deoxyuridine are
      morphologically similar to murine B-type virus.

PMID- 4365980
TI  - Mixed Mullerian tumors of the oviduct.

PMID- 4365979
TI  - Evidence that most noradrenaline is stored without ATP in sympathetic large dense
      core nerve vesicles.

PMID- 4365981
TI  - Individual versus group aftercare treatment.

PMID- 4365983
TI  - [Current aspects of radiologic diagnosis and combined urologic-radiologic
      treatment of malignant kidney neoplasms].

PMID- 4365982
TI  - [T3-thyrotoxicosis in a 3-year-old girl (author's transl)].

PMID- 4365984
TI  - Auxiliary structures of tuberous organ (electroreceptor) of Sternarchus albifrons
      (Gymnotidae).

PMID- 4365985
TI  - The giant melanosome: a model of deranged melanosome-morphogenesis.

PMID- 4365986
TI  - Striated and crystalline inclusions in the nuclei and cytoplasm of intact yeast
      cells and yeast protoplasts.

PMID- 4365987
TI  - Cerebral blood flow in acute hypertension.

PMID- 4365988
TI  - Letter: Acute poliomyelitis disputed.

PMID- 4365989
TI  - Proceedings: Interactions of separate types of cells during normal and neoplastic
      mammary gland growth.

PMID- 4365990
TI  - Proceedings: Hormones and other factors controlling growth in the mammary gland:
      a review.

PMID- 4365991
TI  - Proceedings: Mammogenesis in transsexuals.

PMID- 4365992
TI  - Special diet for familial type II hyperlipoproteinemia.

PMID- 4365993
TI  - Pitfalls in the diagnosis of low-back and leg pain.

PMID- 4365995
TI  - Brain scanning and conventional neuroradiologic methods in intracranial tumours.
      Scanning with 99Tcm and a gamma camera.

PMID- 4365994
TI  - Bone marrow biopsy in malignant disease.

PMID- 4365996
TI  - Cerebral scintiphotos with 113mIn.

PMID- 4365997
TI  - Experience with intraoperative echoencephalography in cerebral mass lesions.

PMID- 4365998
TI  - Unusual myelographic appearances of the lumbosacral radicular sheaths.

PMID- 4365999
TI  - Electron microscopic observations of human retinitis pigmentosa, dominantly
      inherited.

PMID- 4366000
TI  - Retinal degeneration in monkeys induced by deficiencies of vitamin E or A.

PMID- 4366001
TI  - Primary malignant lymphoma of the bladder: case report and review of the
      literature.

PMID- 4366002
TI  - Association between herpes hominis type 2 and the male genitourinary tract.

PMID- 4366003
TI  - Nuclear bodies in papillary carcinomas of the human thyroid gland.

PMID- 4366004
TI  - Megakaryocytes in the May-Heggelin anomaly.

PMID- 4366005
TI  - Hepatic injury associated with penicillin therapy.

PMID- 4366006
TI  - Functional black adenoma of the adrenal gland. Light and electron microscopical
      study.

PMID- 4366007
TI  - An electrophoretic study of the negative correlation of certain carboxylesterases
      to insecticide resistance in Musca domestica L.

PMID- 4366008
TI  - Electron microscope studies on the dissociation of actomyosin by pyrophosphate.

PMID- 4366009
TI  - Effects of GABA on presynaptic nerve terminals in bullfrog (Rana catesbiana)
      sympathetic ganglia.

PMID- 4366010
TI  - Light-microscopic demonstration of drug-induced myelin bodies in the liver of
      rats.

PMID- 4366011
TI  - A renal tumour of the nephroblastoma type in Praomys (Mastomys) natalensis.

PMID- 4366012
TI  - In vitro synthesis of an ACTH-like hormone and human chorionic somatomammotrophin
      by placental and amniotic cells.

PMID- 4366013
TI  - Excretion of equine infectious anemia virus from horses infected with the virus.

PMID- 4366014
TI  - SV40 DNA molecules which contain host cell DNA.

PMID- 4366015
TI  - Studies on the replicase of encephalomyocarditis virus.

PMID- 4366016
TI  - Prostaglandins and cancer: an update.

PMID- 4366017
TI  - Cyclic AMP, prostaglandins, and the control of cell proliferation.

PMID- 4366018
TI  - Effects of prostaglandins on the stomach and the intestine.

PMID- 4366019
TI  - Synaptic organization of the substantia gelatinosa glomeruli in the spinal
      trigeminal nucleus of the adult cat.

PMID- 4366020
TI  - Morphology of the electromotor system in the spinal cord of the electric eel,
      Electrophorus electricus.

PMID- 4366021
TI  - Viral DNA synthesis in cells infected by temperature-sensitive mutants of simian
      virus 40.
AB  - Temperature-sensitive mutants of simian virus 40 (SV40) have been classified as
      those that are blocked prior to viral DNA synthesis at the restrictive
      temperature, "early" mutants, and those harboring a defect later in the
      replication cycle, "late" mutants. Mutants of the A and D complementation groups
      are early, those of the B, C, and BC groups are late. Our results confirm earlier
      reports that A mutants are defective in a function required for the initiation of
      each round of viral DNA synthesis. D mutants, on the other hand, continue viral
      DNA replication at the restrictive temperature after preincubation at the
      permissive temperature. The length of time required for D function to be
      expressed at the permissive temperature-after which infection proceeds unabated
      on shifting of the cultures to the restrictive temperature-is 10 to 20 h. The
      viral DNA synthesized in D mutants under these conditions progresses in normal
      fashion through replicative intermediate molecules to mature component I and II
      DNA molecules.

PMID- 4366022
TI  - Genetic analysis of a temperature-resistant revertant of the conditional lethal
      Escherichia coli double mutant polA12 uvrE502.
AB  - Conditional lethality of the Escherichia coli polA12 uvrE502 double mutant may be
      overcome by a mutation that has been termed polA350. The polA350 mutation
      restored the polymerizing activity of deoxyribonucleic acid polymerase I at 42 C
      in the polA12 mutant and partially suppressed ultraviolet (UV) and methylmethane
      sulfonate sensitivities of the polA12. Mapping experiments have located polA350
      between metE and polA12, very close to the latter. The strain carrying polA12
      polA350 and recB21 was viable at 42 C. The effects of the recB21 and polA12
      polA350 combination on the UV sensitivity were additive. The triple mutant polA12
      polA350 uvrE502 was more UV sensitive than the single uvrE502 mutant.

PMID- 4366023
TI  - Biosynthetic dihydroorotate dehydrogenase from Lactobacillus bulgaricus: partial
      characterization of the enzyme.
AB  - Some of the catalytic properties of the biosynthetic dihydroorotate dehydrogenase
      purified from an anaerobic bacterium, Lactobacillus bulgaricus, are described.
      Studies with p-hydroxymercuribenzoate, N-ethylmaleimide, and mercuric chloride
      showed that sulfhydryl groups are necessary for transfer of electrons from
      dihydroorotate to a variety of electron acceptors. Protection studies with
      substrates for the enzyme indicated that free sulfhydryl groups at or near the
      active center are required for catalytic activity. Evidence is presented for the
      production of superoxide free radicals during reaction of the enzyme with
      molecular oxygen. Inhibitor studies with Tiron indicated that reduction of
      cytochrome c by the enzyme may involve the superoxide free radical as an
      intermediate. Orotate, one of the substrates for the enzyme, has been found to be
      a competitive inhibitor for the dihydroorotate site. The K(i) for orotate as
      estimated by several techniques is 0.1 mM. The K(m) for dihydroorotate with
      ferricyanide as the electron acceptor is estimated to be 0.5 mM.

PMID- 4366024
TI  - Pleiotropic alteration of activities of several toxins and enzymes in mutants of
      Staphylococcus aureus.
AB  - Pleiotropic alteration of several genetic characters including toxin production
      was quantitatively shown with a strain of Staphylococcus aureus of phage type 80,
      81 which had been given a very specific genetic marker (temperature sensitivity
      of mannitol fermentation) to avoid confusion by contamination. Thus, alpha
      hemolysin hyperproducers obtained by N-methyl-N'-nitro-N-nitrosoguanidine (NTG)
      mutagenesis were very often hyperproducers of DNase, coagulase, and protease.
      Their colonies were less yellow than the parent. DNase hyperproducers obtained
      after NTG mutagenesis were also often hyperproducers of alpha-hemolysin,
      coagulase, and protease, with colonies less yellow than the parent. Almost all of
      the revertants obtained by mutagenesis with ethyl methane sulfonate with respect
      to alpha-hemolysin or DNase were shown to have simultaneously become
      hypoproducers of alpha-hemolysin, DNase, and protease. Since the pleiotropic
      alteration of multiple functions was thus quantitatively confirmed, the mechanism
      underlying this phenomenon should probably be related to a regulatory mechanism
      common to them.

PMID- 4366025
TI  - Ribitol catabolic pathway in Klebsiella aerogenes.
AB  - In Klebsiella aerogenes W70, there is an inducible pathway for the catabolism of
      ribitol consisting of at least two enzymes, ribitol dehydrogenase (RDH) and d
      ribulokinase (DRK). These two enzymes are coordinately controlled and induced in
      response to d-ribulose, an intermediate of the pathway. Whereas wild-type K.
      aerogenes W70 are unable to utilize xylitol as a carbon and energy source,
      mutants constitutive for the ribitol pathway are able to utilize RDH to oxidize
      the unusual pentitol, xylitol, to d-xylulose. These mutants are able to grow on
      xylitol, presumably by utilization of the d-xylulose produced. Mutants
      constitutive for l-fucose isomerase can utilize the isomerase to convert d
      arabinose to d-ribulose. In the presence of d-ribulose, RDH and DRK are induced,
      and such mutants are thus able to phosphorylate the d-ribulose by using the DRK
      of the ribitol pathway. Derivatives of an l-fucose isomerase-constitutive mutant
      were plated on d-arabinose, ribitol, and xylitol to select and identify mutations
      in the ribitol pathway. Using the transducing phage PW52, we were able to
      demonstrate genetic linkage of the loci involved. Three-point crosses, using
      constitutive mutants as donors and RDH(-), DRK(-) double mutants as recipients
      and selecting for DRK(+) transductants on d-arabinose, resulted in DRK(+)RDH(+)
      constitutive, DRK(+)RDH(+)-inducible, and DRK(+)RDH(-)-inducible transductants
      but no detectable DRK(+)RDH(-) constitutive transductants, data consistent with
      the order rbtC-rbtD-rbtK, where rbtC is a control site and rbtD and rbtK
      correspond to the sites for the sites for the enzymes RDH and DRK, respectively.

PMID- 4366027
TI  - Regulation of rabbit liver fructose-1,6-diphosphatase. II. Modification by
      lysosomal cathepsin B1 from the same cell.

PMID- 4366028
TI  - Isolating peripheral nerve activity with respect to propagation velocity.

PMID- 4366026
TI  - D-Arabitol catabolic pathway in Klebsiella aerogenes.
AB  - Klebsiella aerogenes strain W70 has an inducible pathway for the degradation of d
      arabitol which is comparable to the one found in Aerobacter aerogenes strain PRL
      R3. The pathway is also similar to the pathway of ribitol catabolism in that it
      is composed of a pentitol dehydrogenase, d-arabitol dehydrogenase (ADH), and a
      pentulokinase, d-xylulokinase (DXK). These two enzymes are coordinately
      controlled and induced in response to d-arabitol, the apparent inducer of
      synthesis of these enzymes. We obtained mutants which lacked a functional d
      xylose pathway and were constitutive for the ribitol catabolic pathway. These
      mutants were able to grow on the unusual pentitol, xylitol, only if they
      contained the functional DXK of the d-arabitol pathway. This provided us with a
      specific selection technique for DXK(+) transductants. As in A. aerogenes,
      mutants constitutive for ADH were able to use this enzyme to convert the hexitol
      d-mannitol to d-fructose. With mutants blocked in the normal d-mannitol catabolic
      pathway, growth on d-mannitol became a test for ADH constitutivity. Growth of
      such mutants on xylitol, d-arabitol, and d-mannitol was utilized to classify
      transductants in mapping, by transductional analysis, the loci involved in d
      arabitol utilization. Three-point crosses gave the order dalK-dalD-dalC, where
      dalK is the DXK structural gene, dalD is the ADH structural gene, and dalC is a
      regulatory site controlling synthesis of both enzymes.

PMID- 4366029
TI  - [Gastrointestinal hormones and regulation of the processes of digestion,
      absorption, and utilization of nutrients].

PMID- 4366030
TI  - Morphologic abnormalities in human infant cerebral white matter related to
      gestational and postnatal age.

PMID- 4366031
TI  - [Effect of various pH values of the medium on some phosphorus compounds in
      Candida utilis].

PMID- 4366032
TI  - Ultrastructural changes in germinating ascospores of Saccharomyces cerevisiae.

PMID- 4366033
TI  - The cytochrome system in Mycobacterium lepraemurium.

PMID- 4366034
TI  - Histoenzymological demonstration of certain phosphatases in the intestinal mucosa
      of common garden lizard Calotes versicolor.

PMID- 4366035
TI  - [Quantitative investigations of the histochemical evidence of GABA-transaminase
      SSA-dehydrogenase (author's transl)].

PMID- 4366036
TI  - [Biochemical similarity between tumor and embryonic cells].

PMID- 4366038
TI  - The acupunture point.

PMID- 4366037
TI  - Hypoglycemia with primary liver cell carcinoma.

PMID- 4366039
TI  - [Platelets, ADP, cAMP, and antiplatelet drugs].

PMID- 4366040
TI  - [Use of the IR spectra of the tubular bones in forensic medicine].

PMID- 4366041
TI  - [Human leucocyte collagenase isolation, purification and properties (author's
      transl)].

PMID- 4366042
TI  - [Bilateral damage of recurrent laryngeal nerves following operations of
      nonmalignant thyroid hypertrophy (author's transl)].

PMID- 4366043
TI  - [Hyperinsulinism and epilepsy].

PMID- 4366044
TI  - The influence of presleep suggestions on dream content: evidence and
      methodological problems.

PMID- 4366045
TI  - Proceedings: The oxidation of catecholamines by hemepeptide obtained from
      enzymatically digested yeast cytochrome C.

PMID- 4366046
TI  - Ultrastructure of the fetal rat adenohypophysis.

PMID- 4366047
TI  - Hepatic cell adenoma: A report of four cases.
AB  - Four patients with hepatic cell adenoma have been treated at the UCLA Hospital
      since 1965. The most recent was a 22-year-old woman who underwent subtotal
      resection of a giant hepatic cell adenoma after an unusual and confusing clinical
      presentation. The tumor may be the largest reported to date and may have excreted
      metabolically-active substances. Increased familiarity with the varying clinical
      and radiographic presentations of these rare tumors may facilitate earlier
      diagnosis and management.

PMID- 4366048
TI  - The retina and optic nerve.

PMID- 4366049
TI  - Vasodilator drugs in the treatment of peripheral arterial insufficiency.

PMID- 4366050
TI  - The effect of plasma cortisol concentration on the pituitary adrenal response
      elicited by electrical stimulation of the infundibular area of the awake
      unrestrained cat.

PMID- 4366051
TI  - Experimental studies of the endolymphatic radiotherapy.

PMID- 4366052
TI  - Expression of the familial hypercholesterolemia gene in heterozygotes: mechanism
      for a dominant disorder in man.
AB  - Studies in ctltured fibroblasts indicate that the primary genetic abnormality in
      familial hypercholesterolemia involves a deficiency in a cell surface receptor
      for low density lipoproteins (LDL). In normal cells, binding of LDL to this
      receptor regulates cholesterol metabolism by suppressing cholesterol synthesis
      and increasing LDL degradation. In cells from heterozygotes, a 60 percent
      reduction in LDL receptors leads to a concentration-dependent defect in
      regulation, so that attainment of equal rates of cholesterol synthesis and LDL
      degradation in normal and heterozygous cells requires a two- to threefold higher
      concentration of LDL in the heterozygote. The identification of this genetic
      regulatory defect in fibroblasts of heterozygotes makes available an in vitro
      system for studying the effects of a dominant mutation on gene expression in
      mammalian cells.

PMID- 4366053
TI  - The effects of Escherichia coli endotoxin and ACTH on the plasma zinc
      concentration in the domestic fowl.

PMID- 4366054
TI  - Collagenolytic enzymes and acid-proteinase activity in granuloma tissue.

PMID- 4366055
TI  - Loss of serum protein from hepatoma-bearing animals.

PMID- 4366056
TI  - Comparison of MHG virus with mouse encephalomyelitis viruses.

PMID- 4366057
TI  - The lipoprotein apoproteins. Their role in normal lipid transport and
      dyslipoproteinemia.

PMID- 4366058
TI  - Neuromuscular transmission in myasthenia gravis studied with single fibre
      electromyography.
AB  - Patients with myasthenia gravis have been investigated with single fibre
      electromyography. In all myasthenic muscles recordings were obtained where there
      was an increase of the jitter and occasional blocking of different degree of
      single fibre action potentials. The jitter is the variability at consecutive
      discharges in the time interval between action potentials from two muscle fibres
      from the same motor unit. During prolonged activity the jitter increased and
      blockings occurred more and more frequently. The size of the jitter and the
      degree of blocking also depended on the discharge rate. At a low rate the jitter
      was lower and the degree of blocking less than at the high rate. Injection of
      edrophonium could decrease or increase the jitter or leave it unaffected. Single
      fibre electromyography is a sensitive way of studying the transmission in
      individual motor end-plates in myasthenia gravis and is also a valuable
      diagnostic aid.

PMID- 4366059
TI  - Oncornavirus expression in human x mouse hybrid cells segregating mouse
      chromosomes.
AB  - Human x mouse hybrid clones obtained by fusing transformed human (VA2) cells with
      embryonic mouse brain cells were tested for their ability to spontaneously
      express type C virus particles. It had been previously shown that these hybrid
      cells preferentially retained human chromosomes while mouse chromosomes were
      lost. The culture fluid from one cell line was found to contain type C particle
      markers in abundance, and typical budding C particles were observed in the cells
      by electron microscopy. In contrast, no particle markers were detected in the
      culture fluid from parental cells and several other hybrid cell lines. Subclones
      of the virus-positive cell line continued to lose mouse chromosomes and were
      found to vary more than 100-fold in their culture fluid DNA polymerase activity.
      The hybrid cell viruses, termed HMV1, banded in a sucrose gradient between 1.14
      and 1.16 g/ml, possessed viral group-specific antigens, and exhibited B-tropic
      host range for replication in mouse embryo cells, but did not replicate in human
      cells when directly applied. The virus did not transform mouse cells but was able
      to rescue the defective murine sarcoma virus from sarcoma-positive, helper-virus
      negative cells. Activity of the DNA polymerase associated with HMV1 was similar
      to the activity of Rauscher murine leukemia virus (MuLV) DNA polymerase in its
      preference for poly(rA) over poly(dA) as a template, use of endogenous template,
      detergent requirement, and inhibition by antiserum directed against MuLV.DNA
      polymerase. The results suggest that human x mouse hybrid cells segregating mouse
      chromosomes can spontaneously express endogenous type C viruses and that such
      hybrid cell lines may be used for the isolation of latent mammalian
      oncornaviruses and analysis of viral gene regulation.

PMID- 4366060
TI  - Role of extrapulmonary conversion in mediating the systemic pressor activity of
      angiotensin I.
AB  - The effect of antibodies against angiotensin II (AII) on systemic pressor
      responses to intravenously injected AII and angiotensin I (AI) was studied in a
      group of bioassay rats. AII antibody was only 29% as effective in neutralizing AI
      given intravenously as it was in neutralizing AII injected by the same route.
      Control plasma caused no change in the relative potencies of AI and AII. In a
      further series of experiments, AII antibody was significantly less effective in
      blocking intra-arterial AI than in blocking intravenous AI. The potency of intra
      arterial AI, initially less than that of intravenous AI, became nearly twice that
      of intravenous AI after antibody administration, a result which could not occur
      if AI were inactive before lung transit. Thus, AI can elicit systemic pressor
      activity independently of pulmonary conversion to AII. However, since the intra
      arterial AI responses were abolished by an inhibitor of angiotensin-converting
      enzyme, the activity would appear to be mediated by peripheral conversion to AII
      rather than by an intrinsic action of the decapeptide. Both series of experiments
      suggest that the efficacy of AII antibody in abolishing the systemic pressor
      activity of AI is highly dependent on the site of conversion of the AI to AII.
      The occurrence of localized intramural conversion of AI to AII near arteriolar
      receptors in vivo may so minimize exposure of the liberated AII to circulating
      antibody as to render AII immunization an inefficient means of blocking
      endogenous pressor activity of the renin-angiotensin system.

PMID- 4366061
TI  - Control of derepressed beta-galactosidase synthesis in Escherichia coli.

PMID- 4366062
TI  - [The effect os estrogen, ACTH and cortisone administration, as well as
      hypophysectomy on histological changes in unilateral renal hilus ligation].

PMID- 4366064
TI  - [Echotomography associated with scanning in hepatology].

PMID- 4366063
TI  - Functional and morphological effects of hypophysectomy and androgen replacement
      in the rabbit epididymis.

PMID- 4366066
TI  - Isolation of temperature-sensitive mutants of mammalian cells.

PMID- 4366065
TI  - Induction and isolation of auxotrophic mutants in mammalian cells.

PMID- 4366068
TI  - Uses of enucleated cells.

PMID- 4366067
TI  - Methods for obtaining revertants of transformed cells.

PMID- 4366069
TI  - Enucleation of somatic cells with cytochalasin B.

PMID- 4366070
TI  - Ionic coupling between nonexcitable cells in culture.

PMID- 4366071
TI  - Methods of cell transformation by tumor viruses.

PMID- 4366072
TI  - Persistent changes induced by subcarcinogenic doses of 3'-methyl-4
      (dimethylamino)azobenzene in rat liver.

PMID- 4366073
TI  - Effect of N-(3,5-dichlorophenyl)succinimide on the histological pattern and
      incidence of kidney tumors in rats induced by dimethylnitrosoamine.

PMID- 4366074
TI  - Variation in the mode of sugar transport among normal and tumor cells.

PMID- 4366076
TI  - Episodic secretion of aldosterone in primary aldosteronism: relationship to
      cortisol.

PMID- 4366075
TI  - Effect of Clostridium perfringens phospholipase C(alpha-toxin) on the human
      diploid fibroblast membrane.

PMID- 4366077
TI  - Physical characterization and simultaneous purification of bacteriophage T4
      induced polynucleotide kinase, polynucleotide ligase, and deoxyribonucleic acid
      polymerase.

PMID- 4366078
TI  - Phosphorylation of N-protected deoxyoligonucleotides by T4 polynucleotide kinase.

PMID- 4366079
TI  - Ribosomal activities dependent on elongation factors T and G. Effects of
      methanol.

PMID- 4366080
TI  - Conformation of nicotinamide adenine dinucleotide bound to cytoplasmic malate
      dehydrogenase.

PMID- 4366081
TI  - Polynucleotides containing 2'-amino-2'-deoxyribose and 2'-azido-2'-deoxyribose.

PMID- 4366082
TI  - Acidophilic activation of steroid hormone receptors.

PMID- 4366083
TI  - Gonadotropin regulation of nucleotide biosynthesis in corpus luteum.

PMID- 4366084
TI  - Studies on the function of central noradrenergic neurons.

PMID- 4366085
TI  - Shape of the hydrophobic barrier of phospholipid bilayers (evidence for water
      penetration in biological membranes).

PMID- 4366087
TI  - Galactosyl-diglyceride from Actinomyces viscosus.

PMID- 4366086
TI  - Regulation of glycolysis in the early development of fish embryos.

PMID- 4366088
TI  - Mass spectra of complex molecules. I. Chemical ionization of sphingolipids.

PMID- 4366089
TI  - [Antibody dynamics against parainfluenza-3 and adenoviruses in cattle].

PMID- 4366090
TI  - Virus, the primordial parasite, and man.

PMID- 4366091
TI  - Herpesviruses, latency and cancer: a biochemical approach.

PMID- 4366093
TI  - The Wilms' tumour--old and new facts. I. Clinical features and tumour biology.

PMID- 4366092
TI  - [Function of the genital system and its effect on the pituitary-adrenal complex
      in male white rats in groups and in isolation].

PMID- 4366094
TI  - The Wilms' tumour--old and new facts. 3. Special problems in therapy.

PMID- 4366095
TI  - Intraoperative upper gastrointestinal endoscopy and biopsy.

PMID- 4366096
TI  - Granuloma annulare and vitamin D resistant rickets.

PMID- 4366097
TI  - Observations on the epidemiology of pseudocowpox in South-west England and South
      Wales.

PMID- 4366098
TI  - Radioimmunoassay of pituitary gonadotropins: serum levels in normal women and
      those with gonadal dysfunction.

PMID- 4366100
TI  - Effect of dibutyryl cyclic amp on glucose-6-phosphatase activity in human fetal
      liver explants.

PMID- 4366099
TI  - The role of estradiol in the equilibrium binding of estrogen receptor to rabbit
      uterine chromatin.

PMID- 4366102
TI  - Effects of decapitation, ether and pentobarbital on guanosine 3',5'-phosphate and
      adenosine 3',5'-phosphate levels in rat tissues.

PMID- 4366101
TI  - Effect of triamcinolone treatment, starvation and diabetes on rat liver protein
      kinase activity.

PMID- 4366103
TI  - The physical chemistry of hemes and hemopeptides. 3. Synthesis and
      physicochemical properties of cytochrome c-related heme--pentapeptide soluble in
      organic solvents.

PMID- 4366105
TI  - Ultrastructure, steroidogenic potential, and energy metabolism of the Snell
      adrenocortical carcinoma 494. A comparison with normal adrenocortical tissue.
AB  - Electron microscope studies were carried out with the adrenocortical carcinoma
      494 and normal adrenal cortex tissue. The mitochondria of the tumor cells showed
      marked differences when compared with mitochondria from fasciculata cells of the
      normal adrenal cortex. These differences were primarily related to mitochondrial
      number and crista structure. Corticosterone production in isolated tumor cells
      was extremely low and neither ACTH nor dibutyryl cyclic AMP had any stimulatory
      effect. Normal adrenal cells showed at least a tenfold increase under identical
      conditions. In the presence of corticosteroid precursors the amount of
      corticosterone produced by the tumor cells was much less than that produced by
      normal cells. The results indicate a reduced capacity for 11beta-hydroxylation in
      the tumor mitochondria and a possible reduced capacity for biosynthetic steps
      before the 11beta-hydroxylation reaction. Glycolysis in isolated tumor cells was
      also lower than in normal cells. Isolated tumor mitochondria oxidized succinate
      normally with a good degree of coupling with phosphorylation. However, unlike
      normal adrenal mitochondria, the tumor mitochondria showed little or no oxygen
      uptake with other Krebs cycle substrates. These data suggest that the tumor
      mitochondria may be lacking in the flavoprotein dehydrogenases responsible for
      the oxidation of NADH and NADPH, although other components of the respiratory
      chain may be intact.

PMID- 4366106
TI  - The enrichment of adenylate cyclase in the plasma membrane and golgi subcellular
      fractions of porcine adenohypophysis.

PMID- 4366104
TI  - Colchicine-induced inhibition of lipoprotein and protein secretion into the serum
      and lack of interference with secretion of biliary phospholipids and cholesterol
      by rat liver in vivo.
AB  - Rats were injected with colchicine and the secretion of triglycerides into the
      serum was studied for 90 min after injection of [(14)C]palmitic acid and Triton
      WR 1339. The release of labeled and chemically determined triglyceride was
      reduced to about 20-30% of control values. The effect of colchicine on serum
      triglyceride levels was not dependent on the presence of Triton and was similar
      in males and females and in fed and fasted rats. The effect was dose dependent
      and was reversible 6-7 h after injection of 0.05 mg/100 g body weight. Colchicine
      inhibited also the release of labeled proteins into the serum but did not affect
      the amount of [(3)H]leucine incorporated into liver proteins. Within 4 h of
      colchicine treatment there was an 80% fall in serum very low density lipoproteins
      (VLDL), a 30% fall in serum high density lipoproteins (HDL), and no change in the
      d > 1.21 protein level, but reduction in the appearance of labeled proteins was
      encountered in all serum fractions. Colchicine had no effect on the rate of bile
      flow and on the secretion of phospholipids and cholesterol into the bile. In the
      hepatocyte there was accumulation of Golgi-derived secretory vesicles, containing
      nascent VLDL particles; these vesicles were seen also in the vicinity of the
      sinusoidal cell surface, but the space of Disse contained few or no VLDL
      particles. There was an apparent reduction in microtubules and some increase in
      microfilaments. It is suggested that microtubules affect the secretion of
      lipoproteins and proteins into the serum by maintaining the organization of the
      plasma membrane required for its fusion with secretory vesicles. The lack of
      effect of colchicine on biliary lipid secretion indicates that the latter is not
      dependent on vesicular transport.

PMID- 4366107
TI  - Effect of dibutyryl adenosine cyclic 3',5'-monophosphate and testololactone on
      concanavalin A binding and cell killing.

PMID- 4366108
TI  - Role of the cell surface in growth and transformation.

PMID- 4366109
TI  - Time on organic evolution.

PMID- 4366110
TI  - A study of the renin-angiotensin system in the nephrotic syndrome.

PMID- 4366111
TI  - The effect of intravenous oestrogen injections on plasma human placental lactogen
      levels.

PMID- 4366112
TI  - Adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices: effect of
      benzodiazepines.

PMID- 4366113
TI  - Alterations in cyclic AMP metabolism associated with photoreceptor cell
      degeneration in the C3H mouse.

PMID- 4366115
TI  - Oat cell tumor of the small bowel.

PMID- 4366114
TI  - Effects of ATP on the activity of nucleoside 3',5'-cyclic monophosphate
      phosphodiesterase from brain.

PMID- 4366116
TI  - Corticotrophin-like peptides in the rat pituitary.

PMID- 4366117
TI  - Purification and characterization of porcine corticotrophin-like intermediate
      lobe peptide.

PMID- 4366118
TI  - DNA synthesis and the secretion of prolactin and growth hormone by the pituitary
      gland of the male rat: effects of diethylstilboestrol and 2-bromo-alpha
      ergocryptine methanesluphonate.

PMID- 4366119
TI  - The thyrotrophin receptor in guinea-pig thyroid homogenate: general properties.

PMID- 4366120
TI  - The thyrotrophin receptor in guinea-pig thyroid homogenate: interaction with the
      long-acting thyroid stimulator.

PMID- 4366121
TI  - Genetic study of the effects of (8-arginine)- and (8-lysine)-vasopressins on
      adenyl cyclase activity of mouse kidney.

PMID- 4366124
TI  - Letter: Serological tests for amoebiasis.

PMID- 4366122
TI  - Virological findings and blood gas tensions in acute lower respiratory tract
      infections in children.
AB  - Sequential blood gas tensions and pH have been measured in 84 children selected
      from 486 admitted to hospital during a 15-month period with acute lower
      respiratory tract infections. Of those selected 73 were treated conservatively
      and 11 by intermittent positive-pressure ventilation; one infant in the latter
      group died. Respiratory syncytial virus (R.S.V.) was isolated from 24 out of 62
      patients studied and the main pathogen in the most severely affected infants.
      Statistical analysis showed that age and R.S.V. infection were independent
      determinants of severity, as reflected by a peak Pco(2) measurement at the height
      of the illness (age, P < 0.01; R.S.V. 0.05 > P > 0.01).

PMID- 4366125
TI  - Studies on hormone-cytostatic complexes in the cytoplasm of rat prostatic gland.

PMID- 4366123
TI  - Acute respiratory failure in bronchiolitis and pneumonia in infancy. Modes of
      presentation and treatment.
AB  - The modes of presentation and the management of acute respiratory failure in 11
      infants with severe lower respiratory tract infections (due to respiratory
      syncytial virus in eight) are described. Progressive respiratory difficulties
      leading to exhaustion, peripheral circulatory collapse, recurrent apnoeic
      attacks, or generalized convulsions were the main clinical presentations
      resulting in severe ventilatory failure. In nine infants preventilation carbon
      dioxide tensions exceeded 65 mm Hg. It seems likely that the use of intermittent
      positive-pressure ventilation in these patients contributed to the low mortality
      rate, less than 0.5%, from such illnesses during the 15-month study period.

PMID- 4366126
TI  - Estracyt (NSC 89199) as a substrate for phosphatases in human serum.

PMID- 4366127
TI  - [Embryopathies and fetopathies caused by pathogenic organisms].

PMID- 4366128
TI  - Cellular hypersensitivity in Guillain-Barre syndrome.
AB  - The Guillain-Barre syndrome is hypothesized to be secondary to cellular
      hypersensitivity to peripheral nerve antigens. To test this theory lymphocytes
      from 100 subjects were studied using the macrophage-migration-inhibition factor
      (MIF) assay. Thirty-four normal controls gave a mean migration of 100.4 +/- 9%.
      Of 34 patients with peripheral nervous system disease, only those with the
      Guillain-Barre syndrome showed hypersensitivity with a mean migration of 72 +/-
      11%. Of 34 patients with central nervous system disease only three with multiple
      sclerosis and two with stroke gave similar results. Positive results in the
      Guillain-Barre syndrome were found only in patients presenting with classical
      disease and who were ill at the time of study.

PMID- 4366129
TI  - Immunology of virus-induced tumours.

PMID- 4366130
TI  - Oncogenic DNA viruses of nonhuman primates: a review.

PMID- 4366131
TI  - [Current study of latent viral infections in man and animals].

PMID- 4366133
TI  - A possible mechanism of 1,2-shift reactions catalyzed by coenzyme B 12 dependent
      enzymes.

PMID- 4366132
TI  - Transvenous adrenal destruction: clinical trials in patients with metastatic
      malignancy.

PMID- 4366134
TI  - The pharmacodynamics of depression and its relation to therapy.

PMID- 4366135
TI  - Beta-islet cell tumors of the pancreas: results of a study on 1,067 cases.

PMID- 4366136
TI  - Contributions of clonal systems to neurobiology.

PMID- 4366137
TI  - [Synthetic polynucleotides as nonspecific stimulators of the body's immunological
      system].

PMID- 4366138
TI  - [Protoplasts from the yeast Rhodotorula gracilis I. Formation of protoplasts
      (author's transl)].

PMID- 4366139
TI  - [Curative treatment of Duhring-Brocq disease by BCG vaccine].

PMID- 4366140
TI  - [A case of peritoneal and pulmonary schistosomiasis caused by S. haematobium].

PMID- 4366141
TI  - [Recurrent hemorrhagic pericarditis revealing adenocarcinoma of probable ovarian
      origin. 4-year survival following pericardectomy].

PMID- 4366142
TI  - [Pseudogout (chondrocalcinosis)].

PMID- 4366143
TI  - [Effect of glucocorticoids and the level of ACTH, TSH, LH and FSH in the human
      serum].

PMID- 4366144
TI  - Studies on the availability of intramitochondrial carbamoylphosphate for
      utilization in extramitochondrial reactions in rat liver.

PMID- 4366145
TI  - Cytochrome c interaction with membranes. Interaction of cytochrome c with
      isolated membrane fragments and purified enzymes.

PMID- 4366147
TI  - On the interpretation of electron paramagnetic resonance spectra of binuclear
      iron-sulfur proteins.

PMID- 4366146
TI  - Effects of membrane steroid modification on human erythrocyte glucose transport.

PMID- 4366148
TI  - Stimulation of cytochrome synthesis in Escherichia coli by cyclic AMP.

PMID- 4366150
TI  - Resonance-raman evidence for anomalous heme structures in cytochrome c' from
      Rhodopseudomonas palustris.

PMID- 4366149
TI  - Polyacrylamide gel electrophoresis of glycoproteins on single concentration and
      gradient gels.

PMID- 4366151
TI  - Purification and properties of a protein which stimulates succinate oxidation in
      the particulate fraction of Azotobacter vinelandii.

PMID- 4366152
TI  - Localization of low-density lipoproteins in atherosclerotic lesions from human
      normolipemics employing a purified fluorescent-labeled antibody.

PMID- 4366153
TI  - [Thermal inactivation of inorganic pyrophosphatase from yeasts].

PMID- 4366154
TI  - Energy-dependent accumulation of iron by isolated rat liver mitochondria. 3.
      Submitochondrial localization of the iron accumulated.

PMID- 4366155
TI  - Biochemical and biophysical studies on cytochrome c oxidase. XVI. Circular
      dichroic study of cytochrome c oxidase and its ligand complexes.

PMID- 4366156
TI  - Articular rhizotomy.

PMID- 4366157
TI  - Synaptic potentials of hypoglossal motoneurons and a common inhibitory
      interneuron in the trigemino-hypoglossal reflex.

PMID- 4366158
TI  - The accumulation of adenosine 3',5'-monophosphate in cerebral cortical slices of
      the quaking mouse, a neurologic mutant.

PMID- 4366159
TI  - Biochemical and physiological properties of a purified snake venom neurotoxin
      which acts presynaptically.

PMID- 4366160
TI  - Characterization of the serum low-density lipoproteins of normal and two rhesus
      monkeys with spontaneous hyperbeta-lipoproteinemia.

PMID- 4366161
TI  - [Cancer and immunosuppressive treatment. Apropos of 2 cases].

PMID- 4366162
TI  - [Polyarthritis preceding viral hepatitis].

PMID- 4366163
TI  - [The specialty of internal medicine in hospital].

PMID- 4366165
TI  - Alcohol dehydrogenases of Euglena gracilis, strain Z.

PMID- 4366164
TI  - Cyclic AMP stimulation of calcium efflux from kidney, liver and heart
      mitochondria.

PMID- 4366166
TI  - A DNA antigen that reacts with antisera to cardiolipin.

PMID- 4366167
TI  - Singlet oxygen generation by the lipoxidase system.

PMID- 4366168
TI  - Liver microsomal electron transport systems. II. The involvement of cytochrome b5
      in the NADH-dependent hydroxylation of 3,4-benzpyrene by a reconstituted
      cytochrome P-448-containing system.

PMID- 4366169
TI  - [Cat cerebral cortex posterior sigmoid and proreal gyrus neuron activity
      following bemegride administration].

PMID- 4366170
TI  - [Physical modeling of neuronal memory as a mosaic of chemo- and electroreceptive
      elements of the somato-dendritic membrane].

PMID- 4366171
TI  - [An analysis of monosynaptic cortico-reticular connections].

PMID- 4366172
TI  - Effect of nuclear protein kinases on mammalian RNA synthesis.

PMID- 4366173
TI  - [In vitro biosynthesis of bovine beta-lipotropic hormone].

PMID- 4366175
TI  - Proceedings: Peptide antagonists of the renin-angiotensin system and the
      elucidation of the receptors for angiotensin-induced drinking.

PMID- 4366174
TI  - Use of (1-14C) aectic anhydride to quantitate diglycerides: a new analytical
      procedure.

PMID- 4366176
TI  - Proceedings: Effects of hypoxia on maternal and foetal renin and angiotensin II
      in sheep.

PMID- 4366177
TI  - The amino-acid sequence of sarcine adenylate kinase from skeletal muscle.

PMID- 4366178
TI  - The muscular atrophy of central origin (an ultramicroscopic study on muscle
      biopsy material).

PMID- 4366179
TI  - [Biochemical and biophysical reactions of rat lung tissue to quartz and corundum
      with and without PVN-oxide treatment].

PMID- 4366180
TI  - Positive and negative control of bacterial gene expression.

PMID- 4366181
TI  - A prospective controlled study of neonatal hypoglycemia.

PMID- 4366182
TI  - [Radioclinical aspects and difficulties of diagnosis in some forms of primary
      bronchopulmonary cancer].

PMID- 4366183
TI  - Performances of Mueller-Hinton agars prepared by three manufacturers.

PMID- 4366184
TI  - Role of the superoxide anion in the myeloperoxidase-mediated antimicrobial
      system.

PMID- 4366185
TI  - Proceedings: Physiology and enzymology of frog photoreceptor membranes.

PMID- 4366186
TI  - Proceedings: Light regulation of adenosine 3',5' cyclic monophosphate levels in
      vertebrate photoreceptors.

PMID- 4366187
TI  - A new overgrowth syndrome with accelerated skeletal maturation, unusual facies,
      and camptodactyly.

PMID- 4366189
TI  - The effects of acetylcholine and of synaptic stimulation on the sensorimotor
      cortex of cats. I. Neuronal responses to stimulation of the reticular formation.

PMID- 4366188
TI  - Lipoproteins in neonates.

PMID- 4366190
TI  - Biochemically active substances from Actinomycetes and other organisms. II.
      Effects of various compounds on motilometry.

PMID- 4366192
TI  - [Natural history of the arthritic synovial membrane].

PMID- 4366191
TI  - Dissociated loss of cold and warm sensibility during regional anaesthesia.

PMID- 4366193
TI  - Fine structure of Bowen's disease in chronic arsenicalism.

PMID- 4366194
TI  - Effects of cis-dichlorodiammine platinum (II) in the regression of sarcoma 180: a
      fine structural study.

PMID- 4366195
TI  - Humoral immune responses to tumor-specific antigens in strain-2 guinea pigs.

PMID- 4366196
TI  - Epithelial cell cultures from normal glandular tissue of mice.

PMID- 4366197
TI  - Summary and recommendations of the workshop on uterine-cervical cancer.

PMID- 4366198
TI  - Respiratory virus inhibitors in the colostrum of Chinese donors.

PMID- 4366199
TI  - Effects of corticotrophin, starvation and glucose on ascorbic acid levels in the
      blood plasma and liver of piglets.

PMID- 4366201
TI  - Purification of alpha-toxin (phospholipase C) of Clostridium perfringens by
      affinity chromatography.

PMID- 4366200
TI  - Lack of fixed order of recruitment in cat motoneuron pools.

PMID- 4366202
TI  - Fine structure of myogenesis and elastogenesis in the developing rat lung.

PMID- 4366203
TI  - A colicin-tolerant mutant of Escherichia coli with reduced levels of cyclic AMP
      and the regulation of lambdoid phage lysogeny.

PMID- 4366204
TI  - [Adenoma of the mamilla].

PMID- 4366205
TI  - Spin-label studies at F9(93)beta of deoxyhemoglobin S aggregation.

PMID- 4366206
TI  - Brenner tumors and Walthard cell nests.

PMID- 4366207
TI  - Atherosclerosis in rat kangaroos.

PMID- 4366208
TI  - [Possible participation of melanin pigment in protecting the fungal cell from
      desiccation].

PMID- 4366209
TI  - Proteinaceous hexagonal inclusions in hyphae of Whetzelinia sclerotiorum and
      Neurospora crassa.

PMID- 4366210
TI  - [Enzyme histochemical studies of islets of Langerhans during postnatal
      development. I. Evidence of oxidoreductases].

PMID- 4366211
TI  - Influence of mesencephalic stimulation on unit activity in striate cortex of
      squirrel monkeys.

PMID- 4366212
TI  - Dynamic characteristics of responses to horizontal head angular acceleration in
      vestibuloocular pathway in the cat.

PMID- 4366213
TI  - A supraspinal monosynaptic input to hindlimb motoneurons in lumbar spinal cord of
      the frog, Rana catesbiana.

PMID- 4366214
TI  - [Current data on human amniotic cytology and their significance for medical
      genetics].

PMID- 4366215
TI  - Phenylethanolamine-N-methyl transferase activity in the avian adrenal following
      immobilization or adrenocorticotropin.

PMID- 4366216
TI  - Transformation by adenovirus type 12 of rat embryol fibroblasts cultivated in the
      presence of interferon.

PMID- 4366217
TI  - Bacterial pathogens in dry dog foods.

PMID- 4366218
TI  - Abnormality in hepatic lipids of a patient having taken coralgil, (hexestrol bis
      (beta-diethylaminoethyl ether)) for a long period.

PMID- 4366220
TI  - [Familial occurrence of cancer].

PMID- 4366219
TI  - Alterations with age in composition and lipolytic activity of adipose tissue from
      male and female chickens.

PMID- 4366221
TI  - The effect of ergocornine on melanophores of Ambystoma tigrinum: evidence for
      suppression of pituitary MSH release.

PMID- 4366222
TI  - Subcutaneous glucagon as a test of the ability of the pituitary to secrete GH and
      ACTH.

PMID- 4366223
TI  - Gas chromatographic resolution of homologous monoacyl and monoalkylglycerols.

PMID- 4366225
TI  - Prostaglandins of rat testis.

PMID- 4366224
TI  - Biosynthesis of monoacyl-sn-glycerol 3-phosphate by rabbit heart mitochondria:
      positional specificity differing from liver enzyme.

PMID- 4366226
TI  - In vivo and in vitro biosynthesis of free fatty alcohols in Escherichia coli K
      12.

PMID- 4366227
TI  - Embryonic vs tumor lipids. II. Changes in phospholipids of developing chick
      brain, heart, and liver.

PMID- 4366228
TI  - The ACTH-enhanced conversion of 118-hydroxyprogesterone to corticosterone in the
      adrenal glands of fetal rhesus monkeys (Macaca mulatta).

PMID- 4366229
TI  - Gas chromatographic differentiation of 4-desmethyl, 4-monomethyl and 4,4
      dimethylsterols.

PMID- 4366230
TI  - Simultaneous radioimmunoassay of testosterone and dihydrotestosterone.

PMID- 4366231
TI  - Extranasopharyngeal juvenile angiofibroma--a case report.

PMID- 4366232
TI  - Plasticity in small neuronal assemblies.
AB  - When spike activity of two or more individual neurons is simultaneously recorded,
      it is possible to detect various types of neuronal connections to and between the
      observed neurons by making appropriate statistical analysis of the data. Such
      methods are reviewed. This approach is particularly useful in seeking changes of
      neuronal connectivity associated with behavioral plasticity. Examples from
      experiments with Aplysia and crayfish are given.

PMID- 4366233
TI  - The role of the renin-angiotensin system in the aldosterone response to acute
      hemorrhage.

PMID- 4366234
TI  - Influence of pure virus infection on wound healing.

PMID- 4366235
TI  - Insulin responses to calcium infusion.

PMID- 4366236
TI  - Alterations in plasma aldosterone levels in response to acute stimuli in kidney
      allograft recipients.

PMID- 4366237
TI  - Influence of altered cyclic 3',5'-adenosine monophosphate phosphodiesterase
      activity on systemic hemodynamics.

PMID- 4366238
TI  - Diagnosis of pulmonary cytomegalic virus by bronchoscopy.

PMID- 4366239
TI  - Histamine and collagen synthesis in keloid and hypertrophic scar.

PMID- 4366240
TI  - Temperature-sensitive mutations in Habrobracon.

PMID- 4366241
TI  - The regulation of NAD L-glutamate dehydrogenase in Aspergillus nidulans.

PMID- 4366242
TI  - Differentiation between the steroidogenic effects of cholera enterotoxin and
      adrenocorticotropin through use of a mutant adrenal cell line.

PMID- 4366243
TI  - Yeast glycogen synthetase in the glucose 6-phosphate-dependent form. II. The
      effect of proteolysis.

PMID- 4366244
TI  - Demonstration of acetylcholine-sensitive adenyl cyclase in malignant
      neuroblastoma cells in culutre.

PMID- 4366246
TI  - Hydroxyproline in the early diagnosis of bone metastases in prostatic cancer.

PMID- 4366245
TI  - Effects of phorbol myristate acetate on the metabolism and ultrastructure of
      neutrophils in chronic granulomatous disease.
AB  - Previous investigations have demonstrated that phorbol myristate acetate (PMA),
      the active principle of croton oil, stimulates alterations in normal
      polymorphonuclear leukocytes (PMN) that resemble closely the changes that develop
      in the cells after phagocytosis of bacteria. The present study has compared the
      effects of PMA and heat-killed bacteria on the oxygen uptake, glucose oxidation,
      nitroblue tetrazolium (NBT) reduction, and ultrastructure of normal neutrophils
      and PMN from six patients with chronic granulomatous disease (CGD). PMA
      stimulated oxygen consumption, hexose monophosphate shunt activity, and NBT
      reduction in normal cells but failed to produce similar effects in CGD
      neutrophils. However, PMA did induce formation of cytoplasmic vacuoles in the CGD
      cells similar to those observed in normal neutrophils. The results indicate that
      PMA is a useful nonparticulate agent for distinguishing between normal and CGD
      neutrophils and for studying basic mechanisms of phagocytosis in normal and
      abnormal PMN.

PMID- 4366247
TI  - Letter: Menetrier disease.

PMID- 4366248
TI  - Sensitivity of serological tests and the diagnosis of streptococcal sore throat
      in children.

PMID- 4366249
TI  - Proceedings: Renin and lysosomal enzyme activities in the kidney of spontaneously
      hypertensive rats.

PMID- 4366250
TI  - Regulation of glycerol catabolism in Klebsiella aerogenes.
AB  - The utilization of glycerol as a carbon source for growth by Klebsiella
      aerogenes, strain 2103, involves separate aerobic (sn-glycerol-3-phosphate or
      G3P) and anaerobic (dihydroxyacetone or DHA) pathways of catabolism. Enzyme and
      transport activities of the aerobic pathway are elevated in cells grown under
      oxygenated conditions on glycerol or G3P. Anaerobic growth on G3P as carbon
      source requires the presence of an exogenous hydrogen acceptor such as fumarate;
      cells thus grown also are highly induced in the G3P pathway. Anaerobic growth on
      glycerol requires no exogenous hydrogen acceptors; cells thus grown are highly
      induced in the DHA pathway but almost uninduced in the G3P pathway and the
      addition of fumarate electron acceptors has no effect on the relative levels of
      the two pathways. When both glycerol and G3P are provided anaerobically with
      fumarate, the DHA pathway is still preferentially induced, which probably
      accounts for the exclusive utilization of glycerol until its exhaustion. These
      observations suggest the presence of a regulatory control of G3P pathway imposed
      by the operation of the DHA pathway.

PMID- 4366252
TI  - Differential diagnosis of an abnormal brain scan.

PMID- 4366251
TI  - Evidence for a composite state of an F'his, gnd element and a cryptic plasmid in
      a derivative of Salmonella typhimurium LT2.
AB  - A method designed to select mutants constitutive for expression of the histidine
      operon has been applied to a Salmonella typhimurium LT2 strain containing an
      F'his,gnd element and a cryptic plasmid. One of the mutants isolated, strain
      AA0019, has not only increased levels of histidinol phosphate phosphatase (hisB),
      but also increased levels of gluconate-6-phosphate dehydrogenase (gnd).
      Ultracentrifugation studies of extrachromosomal deoxyribonucleic acid (DNA)
      isolated from strain AA0019 revealed the presence of a single species of
      covalently closed circular (CCC) DNA that sedimented more rapidly through neutral
      and alkaline sucrose gradients than any of its possible plasmid precursors. From
      neutral sucrose gradients, sedimentation coefficients of 130, 100, and 86S were
      derived, corresponding to the CCC DNA of the large plasmid in strain AA0019, the
      F'his,gnd element and the cryptic LT2 plasmid, respectively. An Escherichia coli
      plasmid-free strain that upon mating had received the large 130S plasmid also
      contained 86S and 100S CCC DNA components. A histidine-requiring derivative of
      strain AA0019 obtained after acridine orange treatment retained the cryptic
      plasmid DNA. Apparently, the large plasmid in strain AA0019 consists of the
      F'his,gnd element and the cryptic LT2 plasmid of the parental strain.

PMID- 4366253
TI  - [Lumbar myelography with a new water-soluble and resorbable contrast medium
      without spinal anesthesia (Dimer X). Results after 757 examinations].

PMID- 4366254
TI  - Papillary cystadenoma lymphomatosum associated with pleomorphic adenoma of the
      parotid gland.

PMID- 4366255
TI  - Juvenile nasopharyngeal angiofibroma.

PMID- 4366257
TI  - [The structure of the high density lipoproteins of the plasma: various properties
      of its protein component].

PMID- 4366256
TI  - [Species and age determination according to microstructure of the bones].

PMID- 4366258
TI  - [Studies on iron and copper in various macromolecules].

PMID- 4366259
TI  - Reusability of silica gel in thin layer chromatography.

PMID- 4366260
TI  - The effects of human serum on local (Ibadan) strains of Entamoeba histolytica.
      (Preliminary studies).

PMID- 4366261
TI  - Proceedings: Long-term follow-up of fluorine-18 bone scans in carcinoma of the
      prostate.

PMID- 4366262
TI  - Proceedings: Urinary hydroxyproline and leucocyte ascorbic acid levels in
      patients bearing breast tumour with skeletal metastases.

PMID- 4366263
TI  - Studies on a new antiviral antibiotic, 9-methylstreptimidone. I. Physicochemical
      and biological properties.

PMID- 4366264
TI  - [Radiotheraphy in the treatment of glomus jugulare tumors].

PMID- 4366266
TI  - [Latency and reactivation of herpes group viruses].

PMID- 4366267
TI  - Formation of interchain disulfide bonds and helical structure during biosynthesis
      of procollagen by embryonic tendon cells.

PMID- 4366265
TI  - Adrenergic receptors and insulin secretion.

PMID- 4366268
TI  - Comparison of proteins of ribosomal subunits and nucleolar preribosomal particles
      from Novikoff hepatoma ascites cells by two-dimensional polyacrylamide gel
      electrophoresis.

PMID- 4366269
TI  - An electrophoretic method for the quantitative isolation of human and swine
      plasma lipoproteins.

PMID- 4366270
TI  - Wilms' tumor.

PMID- 4366271
TI  - [Proceedings: 239. Transmitter release and Ca and Mg: determination of
      association constants (author's transl)].

PMID- 4366272
TI  - [Proceedings: 241. Synaptic transmission of sympathetic ganglion cells].

PMID- 4366273
TI  - [Proceedings: 260. The neuronal construction of the cerebello-vestibulo
      oculomotor control system (author's transl)].

PMID- 4366274
TI  - [Proceedings: 265. Cross dependency and correlation between two single neurons of
      brain stem (author's transl)].

PMID- 4366275
TI  - [Proceedings: 282. Quantitative analysis of the information transmission in
      vestibulo-ocular system (author's transl)].

PMID- 4366276
TI  - [Proceedings: 288. Mono- and polysynaptic transmission in stretch reflex
      (author's transl)].

PMID- 4366277
TI  - [Proceedings: 290. On a new ascending tract transmitting group I impulses from
      hindlimb muscles in the cat (author's transl)].

PMID- 4366278
TI  - [Proceedings: 355. Responses of the amacrine cell of the frog retina (author's
      transl)].

PMID- 4366279
TI  - [Proceedings: 361. Synaptic transmission from hair cells to auditory fibers
      (author's transl)].

PMID- 4366280
TI  - [Histoenzymologic study of secretory tumors of the ovary].

PMID- 4366281
TI  - [Endometritis due to cytomegalovirus].

PMID- 4366282
TI  - Viral disease of the labyrinth. I. Review of the literature and discussion of the
      role of cytomegalovirus in congenital deafness.

PMID- 4366283
TI  - Fat absorption after infusing bile salts into the human small intestine.

PMID- 4366284
TI  - Electron microscopy of small intestinal mucosa in pancreatic insufficiency.

PMID- 4366285
TI  - Jejunal calcium transport in health and metabolic bone disease: Effect of vitamin
      D.

PMID- 4366286
TI  - Changes in the fine structure of mouse gastric epithelium produced by ethanol and
      urea.

PMID- 4366287
TI  - Pathogenesis of herpetic encephalitis in mice after ophthalmic inoculation.

PMID- 4366289
TI  - News. From the National Academy of Sciences: Nomenclature of antigens associated
      with viral hepatitis type B.

PMID- 4366288
TI  - Effect of adenine arabinoside on cytomegalovirus infections.

PMID- 4366290
TI  - Hyperoxia and lung metabolism.

PMID- 4366291
TI  - Clinical trial design in studies of corticosteroids for bacterial infections.

PMID- 4366292
TI  - Letter: Anticoagulant therapy and acute adrenal insufficiency.

PMID- 4366293
TI  - Letter: Androgen role in erythroleukemia after treatment with alkylating agents.

PMID- 4366295
TI  - The frog dorsal column nucleus.

PMID- 4366294
TI  - Use of amoxicillin in the treatment of patients with septic abortion.

PMID- 4366296
TI  - Ribonuclease T1 catalyzed degradation of transfer RNA: an unusual alteration
      induced by urea.

PMID- 4366298
TI  - [A criticism of the fundamental aspects of certain syphilis treatments].

PMID- 4366297
TI  - Evaluation of the role of 5-phosphoribosyl-alpha-1-pyrophosphate synthetase in
      congenital hyperuricemia and gout: a simple isotopic assay and an activity stain
      for the enzyme.

PMID- 4366299
TI  - A theoretical treatment of the turnover of protein-bound phosphate in the
      presence of both protein kinase and phosphatase activities.

PMID- 4366300
TI  - The effect of hypophysial hormones and human chorionic gonadotrophin (HCG) on the
      anencephalic fetal adrenal cortex and on parturition in the human.

PMID- 4366301
TI  - Uptake and relase of (14C)adenine derivatives at beds of mammalian cortical
      synaptosomes in a superfusion system.

PMID- 4366302
TI  - Transfer RNA and the regulation of protein synthesis in rat cerebral cortex
      during neural development.

PMID- 4366304
TI  - [Capability of the electroreceptor system of the Black Sea skate for magnetic
      field reception].

PMID- 4366303
TI  - Comparison of effects of long-term corticotrophin and corticosteroid treatment on
      responses of plasma growth hormone, ACTH, and corticosteroid to hypoglycaemia.
AB  - The development of the highly sensitive cytochemical bioassay for ACTH has
      permitted the measurement of plasma ACTH levels during the insulin hypoglycaemia
      test (I.H.T.) in patients treated with corticosteroids and corticotrophin. The
      ACTH, corticosteroid, and growth hormone (GH) responses in the I.H.T. were
      measured in three groups of 12 rheumatoid arthritis patients. One group was
      receiving long-term corticotrophin treatment, the second was undergoing long-term
      corticosteroid treatment, and the third had never received systemic hormone
      therapy. The increments in plasma ACTH, corticosteroids, and GH were diminished
      in the corticosteroid-treated group, as were increments in plasma GH and ACTH in
      the corticotrophin-treated group; but in this group the corticosteroid increment
      was normal. Examination of the area under the curve of the ACTH response showed
      that the total amount of ACTH secreted was normal though the rate of secretion
      was reduced. In the corticosteroid-treated group both rate and total secretion
      were diminished.

PMID- 4366305
TI  - Methods for selecting and studying temperature-sensitive mutants of BHK-21 cells.

PMID- 4366306
TI  - Reversal of bacteriophage T4 induced polynucleotide kinase action.

PMID- 4366307
TI  - The catecholamines and aggressive behavior.

PMID- 4366308
TI  - [An evaluation of affective value for vocal sign in Macaca fuscata by skin
      potential reflex].

PMID- 4366309
TI  - Experimental herpes infection in the newborn rat. 3. Disease development after
      oral inoculation.

PMID- 4366310
TI  - Conjunctival collagenase: partial purification.

PMID- 4366311
TI  - The pathogenesis of the neuropathy in dimorphous leprosy: electron microscopic
      and cytochemical studies.

PMID- 4366312
TI  - Thyrotrophin responses to intravenous thyrotrophin-releasing hormone in patients
      with hypothalamic and pituitary disease.

PMID- 4366313
TI  - 31P nuclear magnetic resonance: application to the study of human serum high
      density lipoproteins.

PMID- 4366314
TI  - Glycerolipid formation from sn-glycerol-3-phosphate by rat liver cell fractions.
      The role of phosphatidate phosphohydrolase.

PMID- 4366316
TI  - Effect of exogenous adenosine cyclic 3'-5'-monophosphate on antibody-producing
      cells in vivo and in vitro.

PMID- 4366315
TI  - An enzymatic explanation for dietary induced alterations in hepatic glycerolipid
      metabolism.

PMID- 4366317
TI  - [Study of human thyroid stimulator (HTS): comparision with LATS].

PMID- 4366318
TI  - [Determination of low unit urinary HCG with Hi-Gonavis].

PMID- 4366319
TI  - Transcription products synthesized by purified calf thymus DNA-dependent RNA
      polymerase on Shope papilloma virus DNA.

PMID- 4366321
TI  - [Synacthen-depot in dermatology (author's transl)].

PMID- 4366320
TI  - Virus-like particles in human laryngeal papilloma. An ultrastructural study.

PMID- 4366322
TI  - The efficacy of various mutagens and polyene antibiotics for the induction and
      isolation of sterol mutants of Neurospora crassa.

PMID- 4366323
TI  - Rsf mutants of Escherichia coli HfrC defective in the production of the factor
      stimulating recombination in conjugation.

PMID- 4366324
TI  - Methionine biosynthesis in Saccharomyces cerevisiae: mutations at the regulatory
      locus ETH2. I. Genetic data.

PMID- 4366325
TI  - Chemical induction of streptomycin-resistant mutations in Escherichia coli. Dose
      and mutagenic effects of dichlorvos and methyl methanesulfonate.

PMID- 4366326
TI  - Repair replication and unscheduled DNA synthesis in mammalian cell lines showing
      differential sensitivity to alkylating agents.

PMID- 4366328
TI  - The molecular biology of the steroid hormones.

PMID- 4366329
TI  - Effects of oestradiol on different cell types.

PMID- 4366330
TI  - Sequential gene expression in response to estradiol-17 beta during post-natal
      development of rat uterus.

PMID- 4366331
TI  - Effect of prostaglandin E1 on hepatic cyclic AMP activity, carbohydrate and lipid
      metabolism.

PMID- 4366332
TI  - The relationship of transmitter release and storage to fine structure in a
      sympathetic ganglion.

PMID- 4366333
TI  - The substantia gelatinosa Rolandi of the rat. Fine structure, cytochemistry (acid
      phosphatase) and changes after dorsal root section.

PMID- 4366334
TI  - Medical management of the patient with arthritis.

PMID- 4366335
TI  - Tibial osteotomy for the treatment of degenerative arthritis of the knee.

PMID- 4366337
TI  - Stabilization of pathologic fractures with acrylic cement.

PMID- 4366336
TI  - Effect of a surgical horizontal unidirectional filtered air flow unit on wound
      bacterial contamination and wound healing.

PMID- 4366338
TI  - Toxicity of collagenase: the relation to enzyme therapy of disk herniation.

PMID- 4366339
TI  - [Adeno-associated viruses].

PMID- 4366341
TI  - [Morphogenesis of Sindbis virus in intestinal and salivary gland cells of the
      mosquito Aedes aegypti].

PMID- 4366340
TI  - [Karyological study of L cells sensitive and resistant to vesicular stomatitis
      virus].

PMID- 4366342
TI  - [Cleavage of the polypeptide chain of Sendai virus nucleoprotein].

PMID- 4366327
TI  - [The rhino-surgeon's responsibility at rhino-surgery of the face skull adjoining
      the base of the skull (author's transl)].

PMID- 4366344
TI  - Application of the cytochemical bioassay for corticotrophin to clinical and
      physiological studies in man.

PMID- 4366343
TI  - [Properties of parental Sendai virus ribonucleoprotein in nucleoli of cells in
      permissive systems].

PMID- 4366345
TI  - Studies on the mechanism of cytochemical bioassays.

PMID- 4366346
TI  - [The juxtaglomerular apparatus of the kidney in diabetes insipidus (author's
      transl)].

PMID- 4366347
TI  - Lanthanum inhibition of the action of oxytocin on the water permeability of the
      frog urinary bladder: effect on the serosal and the apical membrane.

PMID- 4366349
TI  - [Eosinophilic adenoma of the parotid].

PMID- 4366350
TI  - Cytomegalic inclusion syndrome with thrombocytopenia.

PMID- 4366348
TI  - [Behavior of intradialysis curves of the PRA (Plasma Renin Activity) in a group
      of uremic patients during a periodic hemodialysis treatment].

PMID- 4366351
TI  - On the Nordic Pharmacopoeia limit test for heavy metals. Heating with anhydrous
      sodium sulphate as a source of error.

PMID- 4366352
TI  - Principles of synaptic ultrastructure in the central nervous system.

PMID- 4366353
TI  - [Genetic heterogeneity of the poliomyelitis viruses according to bentonite
      markers].

PMID- 4366354
TI  - [Gas vacuoles in blue-green algae and bacteria].

PMID- 4366355
TI  - The effect of chlorhexidine on some biochemical parameters of rat liver
      microsomes.

PMID- 4366356
TI  - Serial plasma growth hormone concentration during selective removal of pituitary
      tumors in acromegaly.

PMID- 4366357
TI  - Lymphocyte inhibition by mammary tumor virus in patients with breast cancer.

PMID- 4366358
TI  - Collagenase activity in the alkali-burned cornea.

PMID- 4366359
TI  - Experimental liquefaction of the vitreous body.

PMID- 4366362
TI  - Functional morphology of cestode larvae.

PMID- 4366363
TI  - Close genetic linkage of the determinants of the ribitol and D-arabitol catabolic
      pathways in Klebsiella aerogenes.
AB  - Klebsiella aerogenes strain W70 has separate inducible pathways for the
      degradation of the pentitols ribitol and d-arabitol. These pathways are closely
      linked genetically as determined by transduction with phage PW52. There are two
      regulatory sites for the ribitol catabolic pathway as defined by loci for
      mutations to constitutive synthesis of ribitol dehydrogenase and d-ribulokinase,
      rbtB and rbtC. The two control sites are separated by a site represented by the
      dalB22 mutation. This mutation deprives the cell of the ability to induce
      synthesis of d-arabitol dehydrogenase and d-xylulokinase activities. Two
      additional regulatory mutations for the d-arabitol pathway, dalC31 and dalC37,
      map to the opposite side of rbtB13 relative to dalB22. The order of the genetic
      sites thus far determined for this region is dalK-dalD-dalC31, dalC37-rbtB13
      dalB22-rbtC14-rbtD-rbtK, where dalK and dalD represent structural genes for the
      kinase and dehydrogenase of the d-arabitol pathway, respectively, and rbtK and
      rbtD represent the corresponding genes for the ribitol pathway. The two mutations
      that lead to constitutive synthesis of the d-arabitol-induced enzymes, dalC31 and
      dalC37, have different phenotypes with regard to their response to xylitol. The
      growth of dalC31 is inhibited by xylitol, but the toxicity can be reduced by
      increasing the levels of ribitol dehydrogenase either by induction with ribitol
      or by selection of a ribitol dehydrogenase-constitutive mutation.

PMID- 4366364
TI  - Bladder function during lumbar myelography. An experimental investigation in
      cats.

PMID- 4366365
TI  - [Spongy encephalopathy of the van Bogaert-Bertrand type. Intrafamilial
      association with other degenerative diseases].

PMID- 4366366
TI  - Complications in therapeutic soft lens wear.

PMID- 4366367
TI  - Cyclic nucleotide phosphodiesterase activities from isolated fat cells:
      correlation of subcellular distribution with effects of nucleotides and insulin.

PMID- 4366368
TI  - Direct evidence for the involvement of epoxide intermediates in the biosynthesis
      of the C18 family of cutin acids.

PMID- 4366369
TI  - Divalent metal ion effects on a mutant histidinol phosphate phosphatase from
      Salmonella typhimurium.

PMID- 4366370
TI  - Low temperature photodissociation of hemoproteins: oxygenated cobalt-myoglobin
      and hemoglobin.

PMID- 4366371
TI  - Characterization of porcine malate dehydrogenase. II. Amino acid sequence of a
      peptide containing the active center histidine residue.

PMID- 4366372
TI  - Chimpanzee (Pan troglodytes) serum high density lipoproteins. Isolation and
      properties of their two major apolipoproteins.

PMID- 4366373
TI  - [Tumor lipids. A comparative study of the phospholipids of the rat kidneys and
      nephroma RA].

PMID- 4366374
TI  - Biochemical and biophysical studies on cytochrome c oxidase. XVII. An epr study
      of the photodissociation of cytochrome a32+-CO.

PMID- 4366375
TI  - Effects of ATP, antimycin and cyanide on the EPR spectra of cytochromes in
      phosphorylating submitochondrial particles.

PMID- 4366376
TI  - A re-examination of succinic dehydrogenase activity and its association with cell
      death in the interdigit of the chick foot.

PMID- 4366377
TI  - Application of physical methods to the study of serum lipoproteins.

PMID- 4366378
TI  - Half-site reactivity.

PMID- 4366380
TI  - [Abnormalities-induced pulmonary distension caused by pulmonary emphysema alone
      or in association with emphysema in the infant and child].

PMID- 4366379
TI  - The role of the membrane in the utilization of nucleic acid precursors.

PMID- 4366381
TI  - Use of Xavin in auditory nerve lesions.

PMID- 4366382
TI  - Angiotensin I-converting enzyme of the kidney cortex.

PMID- 4366383
TI  - The inhibition of alkaline phosphatase by periodate and permanganate.

PMID- 4366384
TI  - Intracellular localisation and properties of aldehyde dehydrogenases from sheep
      liver.

PMID- 4366385
TI  - Maleimideinactivation of lactate dehydrogenase isozymes.

PMID- 4366386
TI  - Inhibitor of nitrate reductase in the roots of rice seedlings and its effect on
      the enzyme activity in the presence of NADH.

PMID- 4366387
TI  - Kinetics of amidophosphoribosyltransferase in intact tumor cells.

PMID- 4366388
TI  - Partial purification and characterization of an adenosine 3',5'-monophosphate
      dependent protein kinase from rabbit gastric mucosa.

PMID- 4366389
TI  - Activation and phosphorylation of carbonic anhydrase by adenosine 3',5'
      monophosphate-dependent protein kinases.

PMID- 4366390
TI  - Isolation of cyclic inositol-1,2-phosphate from mammalian cells and a probable
      function of phosphatidylinositol turnover.

PMID- 4366391
TI  - Isoenzymes of sphingomyelinase and the genetic defect in Niemann-Pick disease,
      type C.

PMID- 4366392
TI  - Stimulation by thyrotropin of horse thyroid plasma membranes adenylate cyclase:
      evidence of cooperativity.

PMID- 4366393
TI  - Lecithin biosynthesis in liver mitochondrial fractions.

PMID- 4366394
TI  - In vitro triiodothyronine binding to non-histone proteins from rat liver nuclei.

PMID- 4366395
TI  - [Effect of small doses of lead on the growth and the activity of various liver
      and serum enzymes of the white rat].

PMID- 4366396
TI  - Pulmonary carcinoma (Jaagsiekte) of sheep: pathologic findings and comparison in
      multiple-case and case-free herds.

PMID- 4366397
TI  - Comparative studies on some herpes simplex virus strains with different
      locations. 3. Cultivability in cell cultures.

PMID- 4366398
TI  - [Primary hemostatic disorders and osteoarticular diseases].

PMID- 4366399
TI  - Gene manipulation: progress and prospects.

PMID- 4366400
TI  - [Effect of lymphoid cells from hepatectomized mice on the growth of hepatoma
      22a].

PMID- 4366401
TI  - Histologic differences in breast carcinoma of Japanese and American women.

PMID- 4366402
TI  - Lung cancer at autopsy in a-bomb survivors and controls, Hiroshima and Nagasaki,
      1961-1970. I. Autopsy findings and relation to radiation.

PMID- 4366403
TI  - Hereditary tumors of the carotid bodies and chronic obstructive pulmonary
      disease.

PMID- 4366404
TI  - Biosynthesis of yeast mitochondria. Some effects of ethidium bromide on
      Kluyveromyces (Saccharomyces) fragilis.

PMID- 4366405
TI  - Estimation of the mean and variance of cycle times in cinemicrographically
      recorded cell populations during balanced exponential growth.

PMID- 4366406
TI  - Effects of indomethacin on Moloney sarcoma virus-induced tumors.

PMID- 4366407
TI  - [Senai virus ribonucleoprotein in nucleoli of infected cells and its function].

PMID- 4366408
TI  - The study and effect of streptoxotocin (NSC-37917) rendered diabetic Chinese.

PMID- 4366410
TI  - Virologic and serologic studies on infectious mononucleosis-like disease in
      children, with special reference to cytomegalovirus, Epstein-Barr virus and
      adenovirus infections.

PMID- 4366411
TI  - Effect of alpha-methyldopa and of spironolactone on angiotensin responsiveness in
      man.

PMID- 4366409
TI  - Ultrastructure of the tegument of Schistosoma.

PMID- 4366412
TI  - Current evaluation research on mental health services.

PMID- 4366413
TI  - Ego defense patterns in manic-depressive illness.

PMID- 4366414
TI  - Intrinsic urethral peristalsis.

PMID- 4366415
TI  - Genetic influence on development of reticulum cell sarcomas in SJL-J mice.

PMID- 4366416
TI  - Ultrastructure and function of the mesenchyme of the rat adrenal cortex.

PMID- 4366417
TI  - The Nader report: one author's perspective.

PMID- 4366418
TI  - Recurrent sciatica associated with herpes simplex. Case report.

PMID- 4366419
TI  - Early changes of protein-kinase (glycogen-synthetase kinase) in denervated
      muscle.

PMID- 4366420
TI  - Symmetrical transcription in animal cells and viruses.

PMID- 4366421
TI  - Erythema multiforme exudativum (Stevens-Johnson syndrome) following sodium
      diphenylhydantoin therapy.

PMID- 4366422
TI  - Effects of short-term ozone exposure on lung mitochondrial oxidative and energy
      metabolism.

PMID- 4366423
TI  - Complementation in theta-toxin production between mutants of two groups of
      Clostridium perfringens.

PMID- 4366424
TI  - Viral infection and lipemia: a problem of disordered host physiology.

PMID- 4366425
TI  - Transmitter sensitivities of some nerve and muscle cells in culture.

PMID- 4366426
TI  - Short-term toxicity of pentachlorophenol in rats.

PMID- 4366427
TI  - [Comparative study on the problem of absorption and metabolism of the pyrazolone
      derivative metamizole, in man after oral and intramuscular administration].

PMID- 4366428
TI  - Reinitiation within one cell cycle of the deoxyribonucleic acid synthesis induced
      by simian virus 40.
AB  - The infection of secondary cultures of Chinese hamster cells with simian virus 40
      (SV40) induces the appearance of cells with polyploid deoxyribonucleic acid (DNA)
      content or chromosomal component within one cell generation. The mechanism of
      this phenomenon was studied by the use of 5-bromodeoxyuridine (BUdR)
      incorporation as a DNA density marker. When cultures were treated with (14)C-BUdR
      and colcemide and harvested at 48 hr postinfection, only hybrid and light DNA
      molecules were found in control cultures, whereas in infected cultures there were
      also heavy molecules. The proportion of heavy DNA synthesized during the
      experimental period varied from 13 to 25%. It was determined by DNA-DNA
      hybridization that the heavy DNA consisted of cellular DNA. In radioautographic
      experiments, it was shown that, under the conditions used, a fraction of the
      infected cell population twice replicated its complete DNA content. Analysis of
      the kinetics indicated that the heavy DNA resulted from the reinitiation of DNA
      synthesis after the initial replication of the entire cell DNA. It was concluded
      that, after infection with SV40, a fraction of the Chinese hamster cell
      population undergoes two cycles of DNA synthesis without intervening mitosis.

PMID- 4366429
TI  - Isolation and characterization of temperature-sensitive mutants of vesicular
      stomatitis virus, New Jersey serotype.
AB  - Forty-eight temperature-sensitive (ts) mutants have been isolated from a wild
      type strain of the New Jersey serotype of vesicular stomatitis virus (VSV) after
      exposure to the base analogue mutagen 5-fluorouracil. Of these mutants, 47 have
      been classified into 6 nonoverlapping complementation groups containing 21, 17,
      4, 3, 2, and 1 mutant, respectively (1 mutant remaining unallocated). The
      ribonucleic acid (RNA) phenotype of 23 of these mutants has been established.
      Four of the six groups contain one or more mutants unable to synthesize
      detectable amounts of viral RNA under restrictive conditions (39 C). No
      complementation was observed in mixed infection with ts mutants from the five
      established complementation groups of the Indiana serotype of VSV.

PMID- 4366430
TI  - Nucleotide composition of the ribonucleic acid of rabies virus.
AB  - The nucleotide composition of the ribonucleic acid of three strains of rabies
      virus was determined and found to be similar to that of vesicular stomatitis
      virus.

PMID- 4366431
TI  - The accumulative properties of facilitation at crayfish neuromuscular synapses.
AB  - 1. Synaptic facilitation was measured with intracellular recording at two classes
      of neuromuscular synapses in the opener muscle of the crayfish dactyl by placing
      a test stimulus at various intervals after either a single conditioning stimulus
      or a short conditioning train.2. The facilitative effect of one stimulus reaches
      approximately the same level with both the superficial central and superficial
      distal synapses. The facilitation decreases smoothly in two phases after the
      conditioning stimulus at superficial central synapses and in a more complex
      fashion at superficial distal synapses.3. The two synaptic types differ in the
      manner in which they add up the facilitative effects produced by each of the
      stimuli in a short train. With superficial distal synapses the facilitative
      effects of conditioning stimuli add linearly, while with superficial central
      synapses the facilitative effects accumulate exponentially.4. The linear addition
      of facilitation at superficial distal synapses is not altered when the quantal
      content is lowered by decreasing the external Ca concentration from 13.5 to 3
      mM.5. The rate of decay of facilitation is the same following both one and three
      conditioning stimuli, even though the facilitation is nearly six times larger in
      the latter case.6. The results are discussed in terms of mechanisms for synaptic
      facilitation.

PMID- 4366432
TI  - Different properties of synapses between a single sensory neurone and two
      different motor cells in the leech C.N.S.
AB  - In leech ganglia, an individual sensory cell that responds specifically to
      noxious mechanical stimulation of the skin (N cell) excites two different
      motoneurones. One raises the annuli of the skin into ridges (the AE cell), while
      the other innervates logitudinal muscles and thereby shortens the body segment (L
      cell). A comparison has been made of the way in which these two synapses behave
      when their common presynaptic cell is stimulated in various conditions.1. Using
      previously described criteria, N sensory cells have been shown to make
      monosynaptic chemical connexions with both the AE and L motoneurones (Nicholls &
      Purves, 1972). Following a single stimulus, the excitatory synaptic potential
      recorded in the AE motoneurone was only about one tenth the size of that in the L
      cell (approximately 0.5 mV compared to 5 mV). Trains of impulses in the same N
      sensory cell gave rise to synaptic potentials in the AE and the L motoneurones
      that underwent phases of facilitation and depression; the facilitation, however,
      was characteristically greater and longer lasting at synapses upon the AE
      motoneurone.2. The differences between the two synapses were accentuated in
      Ringer fluid containing increased concentrations of Ca and also in the cold.
      Under both of these conditions repetitive firing by the N sensory cell could give
      rise to synaptic potentials in the AE motoneurone which progressively increased
      in amplitude, while those in the L motoneurone became smaller.3. The results
      suggest that the differences in synaptic transmission can be accounted for by
      variations in the amount of transmitter released at the presynaptic N cell
      terminals, rather than by differences in the post-synaptic cells. The animal's
      behaviour corresponds to expectations from the physiology of the synapses.

PMID- 4366433
TI  - [Enzyme histochemical studies in the myocardium of deceased premature newborns
      with respiratory distress syndrom (author's transl)].

PMID- 4366434
TI  - Quantitative and qualitative dynamics of the epidermal and cellular inflammatory
      reaction in primary toxic and allergic dinitrochlorobenzene contact dermatitis in
      guinea pigs.

PMID- 4366435
TI  - Quantitative determination of the conformation of cyclic 3',5'-adenosine
      monophosphate in solution using lanthanide ions as nuclear magnetic resonance
      probes.

PMID- 4366436
TI  - Rapid viscosimetric evaluation of collagenose activity.

PMID- 4366437
TI  - Insulin secretion and glucose metabolism during succinylcholine paralysis in
      dogs.

PMID- 4366438
TI  - Penetration and removal of horseradish peroxidase injected into the cerebrospinal
      fluid: role of cerebral perivascular spaces, endothelium and microglia.

PMID- 4366439
TI  - [On formal genesis of crystalline inclusions in oligodendroglioma (author's
      transl)].

PMID- 4366440
TI  - [The role of viruses in renal pathology. Etiopathogenic aspects].

PMID- 4366442
TI  - [Gas gangrene. Apropos of 24 cases. Value of combined surgical and hyperbaric
      oxygen therapy].

PMID- 4366441
TI  - [Research on the effect of angiotensin on transepithelial transport of sodium].

PMID- 4366443
TI  - [Effects of magnesium therapy in a case vitamin D resistant rickets of the De
      Toni-Debre-Fanconi type].

PMID- 4366444
TI  - [Value of cytodiagnosis in the differential histological criteria for some bucco
      maxillo-facial tumors].

PMID- 4366445
TI  - [An epizootic of Sendai virus infection in a rat colony (author's transl)].

PMID- 4366446
TI  - [Sero-epidemiological observation on mouse hepatitis virus in a mouse breeder
      colony (author's transl)].

PMID- 4366447
TI  - [Histological and histochemical studies of liver cells in an acute intermittent
      hepatic porphyria (author's transl)].

PMID- 4366448
TI  - Evolutionary divergence in the two kinds of subunits of ribulose diphosphate
      carboxylase isolated from different species of Nicotiana.

PMID- 4366449
TI  - Analysis of high molecular weight material from the polymerization of adenosine
      cyclic 2', 3'-phosphate.

PMID- 4366450
TI  - Simultaneous isolation of adenosine 3',5'-cyclic monophosphate (cAMP) and
      guanosine 3',5'-cyclic monophosphate (cGMP) in small tissue samples.

PMID- 4366451
TI  - Flotation equilibrium of serum low density lipoproteins.

PMID- 4366452
TI  - An enzymatic, spectrophotometric glycerol assay with increased basic sensitivity.

PMID- 4366453
TI  - Adrenal-gonadal interactions at puberty.

PMID- 4366454
TI  - Nuclear receptor-estrogen complex: in vivo and in vitro binding of estradiol and
      estriol as influenced by serum albumin.

PMID- 4366455
TI  - Steroid excretion in the neo-natal period: a comparative study of the excretion
      of steroids by human, ape and rhesus monkey infants.

PMID- 4366456
TI  - Radioimmunoassay for aldosterone and normal values under various physiological
      conditions.

PMID- 4366457
TI  - Demonstration of an androgen binding protein (ABP) in rabbit testis: secretion in
      efferent duct fluid and passage into epididymis.

PMID- 4366458
TI  - Specificity of cyclic AMP potentiation of glucose-stimulated insulin release.

PMID- 4366459
TI  - Influence of adrenal steroidogenesis in urinary excretion of catecholamine acid
      metabolites.

PMID- 4366460
TI  - Glucose transport in isolated brush-border and lateral-basal plasma-membrane
      vesicles from intestinal epithelial cells.

PMID- 4366461
TI  - On the sidedness of plasma membrane enzymes.

PMID- 4366462
TI  - The effect of oxygen on the photoconductivity of lipid bilayers containing
      magnesium-porphyrin.

PMID- 4366463
TI  - Two variants of feedback artificially created in central motor disturbances on
      the base of EMG.

PMID- 4366464
TI  - [Malignant synovioma in the dog].

PMID- 4366465
TI  - Photooxidative and spectral studies on cytochrome c. Conformational changes
      induced by binding of cardiolipin.

PMID- 4366466
TI  - [Herpetic meningoradiculitis].

PMID- 4366467
TI  - Characteristics of the sensory discharge of the muscle spindle in Xenopus laevis.

PMID- 4366468
TI  - Modification of fructose-1,6-diphosphatase with pyridoxal 5'-phosphate. Evidence
      for the participation of lysyl residues at the active site.

PMID- 4366469
TI  - Neurospora arginyl transfer ribonucleic acid ligase. Binding and dissociation of
      transfer ribonucleic acid.

PMID- 4366470
TI  - Chemical polymerization of oligonucleotides directed by a complementary
      polynucleotide. Preparation and polymerization of oligo(2'-O-methylinosine 3'
      phosphate).

PMID- 4366471
TI  - Substrate and product inhibition in the xanthine oxidase catalyzed oxidation of
      acetaldehyde.

PMID- 4366472
TI  - Contribution of carotenoids to the optical activity of human serum low-density
      lipoprotein.

PMID- 4366473
TI  - Linear electric field effect measurements of variant low-spin forms of ferric
      cytochrome c.

PMID- 4366474
TI  - Interactions of periodate-oxidized guanine nucleotides with Escherichia coli
      elongation factor G and the ribosome.

PMID- 4366475
TI  - Chemical linkage of nucleic acids to neutral and phosphorylated cellulose powders
      and isolation of specific sequences by affinity chromatography.

PMID- 4366476
TI  - The genetics of Caenorhabditis elegans.
AB  - Methods are described for the isolation, complementation and mapping of mutants
      of Caenorhabditis elegans, a small free-living nematode worm. About 300 EMS
      induced mutants affecting behavior and morphology have been characterized and
      about one hundred genes have been defined. Mutations in 77 of these alter the
      movement of the animal. Estimates of the induced mutation frequency of both the
      visible mutants and X chromosome lethals suggests that, just as in Drosophila,
      the genetic units in C. elegans are large.

PMID- 4366477
TI  - Gel electrophoresis, isoelectric focusing, and localization of thymidine kinase
      in normal and simian virus 40-infected monkey cells.

PMID- 4366478
TI  - On the nature of the hemolytic activity of Sendai virus. A kinetic study.

PMID- 4366479
TI  - Enzyme activities associated with cytoplasmic polyhedrosis virus from Bombyx
      mori. II. Comparative studies.

PMID- 4366480
TI  - Induction of common transplantation antigen by various isolates of papovavirus
      SV40 and by virus rescued from transformed cells.

PMID- 4366481
TI  - Sanfilippo A disease in the fetus.

PMID- 4366483
TI  - E.s.r.-spectroscopy of radiation-produced radicals in 9-ethyl adenine.

PMID- 4366482
TI  - Polysyndactyly and Marfan's syndrome.

PMID- 4366484
TI  - [Letter: Radiation-induced free radicals in frozen solutions of 5
      methylcytosine].

PMID- 4366485
TI  - [Prolonged remission in Cushing's syndrome following treatment with ortho-para
      dichlordiphenyldichlorethane].

PMID- 4366486
TI  - [Letter: Observation of herpes zoster patients during ACTH (Synacten depot)
      treatment].

PMID- 4366487
TI  - [Cases of paravaccinia (milkers' nodules) in man, caused by contact with a bovine
      focus].

PMID- 4366488
TI  - Insulin binding to isolated human adipocytes.

PMID- 4366489
TI  - Genetic variation in coumarin hydroxylase activity in the mouse (Mus musculus).
AB  - Basal and phenobarbital-induced rates of hepatic metabolism of coumarin to 7
      hydroxycoumarin are markedly higher in DBA/2J mice than they are in the AKR/J,
      C57BL/6J, and C3H/HeJ strains. Intermediate coumarin hydroxylase activity in F(1)
      hybrids of mating between DBA/2J and the other three strains indicates an
      additive mode of inheritance.

PMID- 4366490
TI  - Absence of REM rebound after barbiturate withdrawal.
AB  - Administration of three different barbiturates reduced rapid eye movement (REM)
      sleep. Drug withdrawal led to a return to baseline REM] values without
      significant overshoot. Similar results are observed with administration of
      benzodiazepines in pharmacologically equivalent dosages; therefore, a distinction
      between these two drug classes on the basis of withdrawal effects on the sleep
      electroencephalogram appears unwarranted. Further investigation is required
      determine why high REM levels are sometimes associated with the withdrawal of
      sedative-hypnotic agents.

PMID- 4366491
TI  - Increased sensitivity of cell-free protein synthesis to double-stranded RNA after
      interferon treatment.

PMID- 4366492
TI  - Comparative studies on tomato aspermy and cucumber mosaic viruses. II. Virus
      stability.

PMID- 4366493
TI  - Partial suppression by UV irradiation of the mechanism of resistance to cucumber
      mosaic virus in a resistant cucumber cultivar.

PMID- 4366494
TI  - Posttranscriptional block to adenovirus replication in nonpermissive monkey
      cells.

PMID- 4366495
TI  - Production of interferon-like substance by mouse spleen cells through contact
      with BHK cells persistently infected with HVJ.

PMID- 4366496
TI  - Rescue of simian virus 40 (SV 40) from SV40-transformed cells by fusion with
      anucleate monkey cells and variation in the yield of virus rescued by fusion with
      replicating or nonreplicating monkey cells.

PMID- 4366497
TI  - Carbohydrate composition of the membrane glycoprotein of vesicular stomatitis
      virus.

PMID- 4366498
TI  - Influence of increasing 2'-O-methylation on the interferon stimulating capacity
      of poly(rl)-poly(rC).

PMID- 4366499
TI  - Transcription of herpes simplex type 1 DNA in nuclei isolated from infected HEp-2
      and KB cells.

PMID- 4366500
TI  - Redetermination of the RNA content and the limiting RNA size of three strains of
      cucumber mosaic virus.

PMID- 4366501
TI  - Cross-reacting tumor-associated antigen (s) among chemically induced rat colon
      carcinomas.

PMID- 4366502
TI  - Synthesis of alpha-fetoprotein by membrane-bound polysomes of rat ascites
      hepatoma cells.

PMID- 4366503
TI  - Deviation in esterase isozyme pattern during early stage of hepatocarcinogenesis
      by 3'-methyl-4-dimethylaminoazobenzene.

PMID- 4366504
TI  - Virus release by cell colonies derived from chickens and cultures infected with
      avian myeloblastosis virus.

PMID- 4366505
TI  - Effect of nitrofurans antagonistic to 3'-methyl-4-dimethylaminoazobenzene in
      hepatocarcinogenesis and RNA polymerase activity of liver cell nuclei in rats.

PMID- 4366506
TI  - Proceedings: Proposed mechanisms by which autochthonous neoplasms escape immune
      rejection.

PMID- 4366507
TI  - Proceedings: The graded enzymic immaturity of transplanted neoplasms.

PMID- 4366508
TI  - Hormonal interactions among GH, ACTH, cortisol and dexamethasone upon size of
      kidney, liver, and adrenal.

PMID- 4366509
TI  - Identification by immunofluorescence of adenoviral antigen in exfoliated bladder
      epithelial cells from patients with acute hemorrhagic cystitis.

PMID- 4366511
TI  - Interferon cell species specificity: role of cell membrane receptors.

PMID- 4366510
TI  - Depressed growth of Morris hepatomas and altered lysosomal hydrolases during
      altitudinal hypoxia.

PMID- 4366512
TI  - Growth of Novikoff hepatoma cells in the presence of long-chain fatty acids.

PMID- 4366513
TI  - Epidermal cell-leukocyte interactions in spongiform pustules of Kogoj. An
      ultrastructural study.

PMID- 4366514
TI  - Progressive multifocal leukoencephalopathy with paramyxovirus-like structures,
      Hirano bodies and neurogibrillary tangles.

PMID- 4366515
TI  - Morphological and biochemical observations in the Jimpy spinal cord.

PMID- 4366516
TI  - Steroid therapy of multiple myeloma and macroglobulinemia.

PMID- 4366517
TI  - The structure of the gills of the elasmobranch, Scyliorhinus canicula (1).

PMID- 4366518
TI  - [Infrastructural aspects of the secretion in the glandular cells of the
      vasdeferens in Porcellio scaber Latreille (terrestial Isopoda) (author's
      transl)].

PMID- 4366519
TI  - The molecular basis of connective tissue pathology.

PMID- 4366520
TI  - Nerve and muscle stimulation of the rat isolated phrenic nerve-diaphragm
      preparation.

PMID- 4366522
TI  - Characteristics of aortic diastolic pressure decay with application to the
      continuous monitoring of changes in peripheral vascular resistance.

PMID- 4366521
TI  - Hyperlipoproteinaemia in peripheral arterial disease in the north of England.

PMID- 4366523
TI  - Copper content and exchange in mammalian hearts.

PMID- 4366524
TI  - Effect of ischemia on capillary pressure and equivalent pore radius in
      capillaries of the isolated dog hind limb.

PMID- 4366525
TI  - Studies on the cardiomegaly of the spontaneously hypertensive rat.

PMID- 4366526
TI  - Lipoprotein uptake and metabolism by rat aortic smooth muscle cells in tissue
      culture.

PMID- 4366528
TI  - [Determination of the individual sensitivity of gastric cancerous tumors to 5
      fluorouracil according to respiratory and glycolytic indices].

PMID- 4366527
TI  - [State of the androgen function of the adrenal cortex in chronic cholangitic
      hepatitis].

PMID- 4366529
TI  - [Anatomical and virological findings in herpes simplex encephalitis].

PMID- 4366530
TI  - A Raman and infrared spectroscopic study of the 3-carbonyl group of pyridine
      nucleotide coenzymes and related model compounds.

PMID- 4366531
TI  - Separation of ribonucleotides and deoxyribonucleotides on columns of borate
      covalently linked to cellulose. Application to the assay of ribonucleoside
      diphosphate reductase.

PMID- 4366532
TI  - Chemical studies on the cyanogen bromide peptides of rat skin collagen. Amino
      acid sequence of alpha 1-CB3.

PMID- 4366533
TI  - Electron-microscopic investigation of pathologic inclusions in neuron
      mitochondria during retrograde degeneration.

PMID- 4366534
TI  - [Chromatographic separation of chicken liver lactate dehydrogenase and xanthine
      dehydrogenase].

PMID- 4366535
TI  - Study of free and bound lipids of Brassica campestris, var yellow sarson.

PMID- 4366536
TI  - Unusual lipids. II. Head oil of the north atlantic pilot whale, Globicephala
      melaena melaena.

PMID- 4366537
TI  - In vitro activity of delta 6 and delta 9 desaturases in hepatomas of different
      growth rates.

PMID- 4366539
TI  - Enhancement by rat liver preparations of the gene conversion frequency induced by
      ethyl methanesulphonate in Saccharomyces cerevisiae.

PMID- 4366538
TI  - Comparative studies of the effects of carcinogenic and antitumor agents on the
      DNA replication of cultured mammalian cells.

PMID- 4366540
TI  - [Changes in nervous system in sarcoidosis].

PMID- 4366541
TI  - Effect of actinomycin D, cycloheximide and puromycin on hepatic adenosine 3',5'
      monophosphate in rats treated with glucagon.

PMID- 4366542
TI  - [Value of combined radiologic methods. Radiology].

PMID- 4366543
TI  - [Value of combined radiologic methods. Urology].

PMID- 4366544
TI  - [Value of combined radiology-nuclear medicine examination methods in nephrology].

PMID- 4366545
TI  - [Value of ultrasonic tomography in kidney neoplasms].

PMID- 4366546
TI  - [Ultrasonic examination of the kidney in the differential diagnosis between
      tumors and cysts].

PMID- 4366547
TI  - [Nuclear-medicine function diagnostics and x-ray morphology in changed kidney
      location (tilted kidney without ptosis)].

PMID- 4366548
TI  - [Nuclear medicine and radiologic diagnosis of renal hypertension].

PMID- 4366549
TI  - [Diagnostic studies of the afferent urinary pathways using a gamma-camera].

PMID- 4366550
TI  - [Indication and value of angiographic and nuclear medicine studies following
      kidney transplantation 1,2].

PMID- 4366551
TI  - [Function-scintigraphy, angiography and excretion urography in transplanted
      kidneys. Xenogenous transplantation in animal experiments].

PMID- 4366552
TI  - [Ultrasonics, thermography and radiology--combined use. Further progress in
      current neuroradiology].

PMID- 4366553
TI  - [Value of radiological and scintigraphic examination in the diagnosis of
      recurrent cerebral tumors].

PMID- 4366554
TI  - [Clinical significance of brain scintigraphy].

PMID- 4366555
TI  - [Value of combined radiologic methods in neuroradiology].

PMID- 4366556
TI  - [Value of angiography and scintigraphy in cerebrovascular diseases].

PMID- 4366557
TI  - [Value of thermography, scintigraphy and angiography in brain infarction].

PMID- 4366558
TI  - [Ultrasonic tomography and isotope diagnostics as ideal supplementary
      examinations in intracranial space-requiring processes in childhood].

PMID- 4366559
TI  - [Diagnostic value obtained through the rational use of neuroradiological and
      nuclear medicine, technics as illustrated on the example of meningioma].

PMID- 4366561
TI  - [Demonstration of brain metastases using various research methods].

PMID- 4366560
TI  - [Diagnosis of intravital brain death using radioisotope angiography].

PMID- 4366562
TI  - [Value of x-ray diagnosis and nuclear medicine in bone and joint diseases].

PMID- 4366563
TI  - [Comparative studies with 87m-Sr, 99m-Tc-pyrophosphate and 99m-Tc-polyphosphate
      in patients with imflammatory joint diseases and Bechterew's disease].

PMID- 4366564
TI  - [Comparative significance of studies with 87m-Sr and 113m-In in relation to
      radiologic and clinical findings in inflammatory joint diseases with reference to
      course control].

PMID- 4366565
TI  - [Bone scintigraphy in osteomyelitis and tumors].

PMID- 4366566
TI  - [Value of combined radiological methods in the field of skeletal diseases].

PMID- 4366567
TI  - [X-ray diagnosis and scintigraphy of peripheral joints in patients with chronic
      polyarthritis].

PMID- 4366568
TI  - [Comparative x-ray, scintigraphic and clinico-chemical studies for the
      demonstration of bone metastases in prostatic carcinoma].

PMID- 4366569
TI  - [Comparison of x-ray diagnostics of skeletal diseases using calcium kinetics and
      scintigraphy].

PMID- 4366570
TI  - [Comparison of radiological and scintigraphic examination technics in bone
      diseases].

PMID- 4366571
TI  - [Value of combined radiologic methods in bone diseases].

PMID- 4366572
TI  - [Comparison of x-ray diagnosis and nuclear medicine in bronchi obstructive lung
      diseases].

PMID- 4366573
TI  - [Value of angiography in liver and pancreatic diseases].

PMID- 4366574
TI  - [Value of endoscopic, retrograde cholangio-pancreatography].

PMID- 4366575
TI  - [Combined use of ultrasonics, scintigraphy and hepatic arteriography for the
      demonstration of liver metastases].

PMID- 4366576
TI  - [Cine-densitometric and nuclear medicine studies on liver and portal perfusion in
      portal hypertension].

PMID- 4366577
TI  - [Value of radiological methods in liver and gallbladder diseases].

PMID- 4366578
TI  - [Use of local anesthetics in the after care of irradiated tumor-patients].

PMID- 4366579
TI  - [After care in Hodgkin's disease (pathology)].

PMID- 4366580
TI  - [Indication and achievements of after-care examinations in Hodgkin's disease.
      Splenectomy].

PMID- 4366581
TI  - [Indication and achievements of after-care examinations in Hodgkin's disease.
      Ultrasonics].

PMID- 4366582
TI  - [Indication and achievements of after-care examinations in Hodgkin's disease from
      the radiotherapist' viewpoint].

PMID- 4366584
TI  - [Cooperation between the internist and radiologist in the treatment and after
      care of patients with lymphogranulomatosis].

PMID- 4366583
TI  - [Various problems in radical radiotherapy of Hodgkin's disease].

PMID- 4366585
TI  - [Diagnosis of recurrence and therapy in Hodgkin's disease].

PMID- 4366586
TI  - [Splenectomy in Hodgkin's disease].

PMID- 4366587
TI  - [Incidence and diagnosis of recurrence in lymphogranulomatosis with mediastinal
      involvement].

PMID- 4366588
TI  - [Lymphography during the course of lymphogranulomatosis].

PMID- 4366589
TI  - [Value of single examination methods in after care for the early diagnosis of
      liver metastases].

PMID- 4366590
TI  - [Value of liver scintigraphy as compared to laparoscopy in the after care of
      tumor-patients].

PMID- 4366591
TI  - [Pathologico-anatomical notes on the problem of after care in kidney and urethral
      neoplasms].

PMID- 4366592
TI  - [Internal-medicine after care in treated urologic tumor-patients].

PMID- 4366594
TI  - [Indication and achievement of after-care examinations of urologic tumors.
      Nuclear medicine].

PMID- 4366593
TI  - [X-ray diagnosis of recurrences in malignant urogenital tumors].

PMID- 4366595
TI  - [Indication and achievement of after-care examinations of urologic tumors.
      Ultrasonics].

PMID- 4366596
TI  - [Indication and achievement of after-care examinations of urologic tumors.
      Urogram, scintigram, aortogram, comparative study results].

PMID- 4366597
TI  - [Surgical report. After care study of urologic tumors].

PMID- 4366598
TI  - [After care in bladder and urethral carcinoma].

PMID- 4366599
TI  - [Comparison and course observations in skeletal-metastases and primary bone
      tumors using 87mSr, 85mSr. 99mTc-pyrophosphate, 99mTc-polyphosphate and x-ray
      diagnosis].

PMID- 4366600
TI  - [Radiotherapy of tumors in childhood. Report on the 1st x-ray therapy case in
      Vienna (Leopold Freund, 1896)].

PMID- 4366601
TI  - [Chemotherapy].

PMID- 4366602
TI  - [Radiotherapy of bone tumors in childhood].

PMID- 4366604
TI  - [Discussional comment on the radiotherapy of lymphogranulomatosis in childhood].

PMID- 4366603
TI  - [Radiotherapy of lymphogranulomatosis in childhood].

PMID- 4366605
TI  - [Contribution of the radiologist to the diagnosis and therapy of Wilms' tumor].

PMID- 4366606
TI  - [Results of radiotherapy in 228 children with retinoblastomas].

PMID- 4366607
TI  - [Report on experiences in the treatment of childhood leukoses using irradiation
      of the CNS and combined cytostatic medication].

PMID- 4366608
TI  - [Irradiation of the CNS in acute leukoses within the scope of 1st attack
      treatment].

PMID- 4366609
TI  - [Therapy and course of malignant diseases of the lymphoreticular system in
      infancy and early childhood].

PMID- 4366610
TI  - [Ewing's sarcoma: report on 36 cases].

PMID- 4366611
TI  - [Surgery and drug therapy of Ewing's sarcoma].

PMID- 4366612
TI  - [Therapy and prognosis of sarcomas in childhood].

PMID- 4366613
TI  - [Results of radio and chemotherapy for malignant tumors after partial
      synchronization by blocking the synthesis-phase].

PMID- 4366614
TI  - [Mammo-elastography].

PMID- 4366615
TI  - [Clinical aspects, mammography, cytology, stamp-biopsy and thermography in breast
      diagnostics].

PMID- 4366616
TI  - [Value of combined mammography and plate-thermography in breast diagnostics].

PMID- 4366617
TI  - [Thermography, a central component of a large preventive health care unit].

PMID- 4366618
TI  - [Local early recurrence in carcinoma of the breast].

PMID- 4366619
TI  - [Current dosimetry within the scope of radiotherapy for gynecologic neoplasms].

PMID- 4366620
TI  - [Significance of excretion urography in the after care of treated gynecological
      neoplasms].

PMID- 4366621
TI  - [Therapeutic procedure in carcinoma of the collum at the Oncological Research
      Institute in Sofia].

PMID- 4366623
TI  - [Individual dosimetry using a computer during the pendulum irradiation of
      gynecologic tumors].

PMID- 4366622
TI  - [Correlation of morphological and radiological findings following endolymphatic
      administration of radioactive isotopes].

PMID- 4366624
TI  - [Surgical treatment of peripheral circulation disorders].

PMID- 4366625
TI  - [Angiographic control after surgical treatment of peripheral circulation
      disorders].

PMID- 4366626
TI  - [Percutaneous treatment of arterial occlusive diseases of the limbs using a
      catheter].

PMID- 4366627
TI  - [Pharmacoangiography in blood circulation disorders of the limbs].

PMID- 4366628
TI  - [Isotope diagnosis in blood circulation disorders of the limbs].

PMID- 4366629
TI  - [Radio-fibrinogen test in the diagnosis of fresh thrombophlebitis].

PMID- 4366631
TI  - [Angiographic, neurographic and electromyographic studies on the limbs in
      peripheral blood circulation disorders].

PMID- 4366630
TI  - [Early diagnosis of thrombosis in the lower limbs using I-125-fibrinogen in
      patients with total prosthesis of the hip joint].

PMID- 4366632
TI  - [Phebographic studies in the treatment of acute deep thrombophlebitis using
      thrombolysis and anticoagulants].

PMID- 4366633
TI  - [Postoperative x-ray control in plastic surgery of the veins].

PMID- 4366635
TI  - [Angiographic course observation in femoral-popliteal venous bypass].

PMID- 4366634
TI  - [Course evaluation in venous diseases of the arm and leg with special reference
      to phlebography].

PMID- 4366636
TI  - [Postoperative control from the angiographic and functional viewpoints].

PMID- 4366637
TI  - [Control angiography after reconstructive vascular surgery on the limbs].

PMID- 4366638
TI  - [Significance of angiography for the indication, surgical procedure and prognosis
      in peripheral blood circulation disorders].

PMID- 4366640
TI  - [Results of surgical interventions following vascular injuries as seen in the
      angiogram].

PMID- 4366639
TI  - [Contribution of arteriography to the evaluation of operability in vascular
      occlusions of lower limbs].

PMID- 4366641
TI  - [Data on the aneurysmatic form of arteriosclerosis in the lower limb].

PMID- 4366642
TI  - [Possibilities and limitations of ambulatory angiographies].

PMID- 4366643
TI  - [Postoperative x-ray-cinematography and serial angiography following
      thromboendarterectomy].

PMID- 4366644
TI  - [Results of transluminal vascular catheterization using Dotter's method--course
      observation using Doppler's ultrasonic pressure measurements].

PMID- 4366645
TI  - [Special aspects of transluminal catheter-recanalization using Dotter's method].

PMID- 4366646
TI  - [Assessment on the blood circulation in the limbs using autofluoroscopy].

PMID- 4366647
TI  - [Determination of blood supply to muscles during constant load under simplified
      working conditions using 133-Xe-clearance].

PMID- 4366649
TI  - [Collateral connections in occlusions of the terminal aorta and the big pelvic
      arteries].

PMID- 4366648
TI  - [Nuclear medicine studies on the legs in stage 3 and IV of arterial occlusive
      disease].

PMID- 4366650
TI  - [Comparison of angiographic and scintigraphic findings in various pancreatic
      diseases].

PMID- 4366651
TI  - [Animal experiment liver function tests following directed Co-60 irradiation with
      radionuclides].

PMID- 4366652
TI  - [Comparison of scintigraphic and x-ray determinations of the spleen-size in
      splenomegaly].

PMID- 4366653
TI  - [Thermography, ultrasonics and radiology--an ideal examination procedure for
      patients with neuro-ophthalmologic problems].

PMID- 4366654
TI  - [Comparative x-ray and bone scintigraphic studies in diseases of the paranasal
      sinuses].

PMID- 4366655
TI  - [Long-term after-care examinations in patients with irradiated breast using lung
      scintigraphy].

PMID- 4366656
TI  - [Color-scintigraphy of the heart cavities and great vessels].

PMID- 4366657
TI  - [Gallium 67 in the diagnosis of neoplasms].

PMID- 4366658
TI  - [Value of isotope-lymphography in the diagnosis of melanoblastoma].

PMID- 4366659
TI  - [Studies on a new model of 47 Calcium kinetics].

PMID- 4366660
TI  - [Sialographic and scintigraphic comparative studies in salivary gland diseases].

PMID- 4366662
TI  - [Analysis of the effect of minimal irradiation doses].

PMID- 4366661
TI  - [Comparison of nuclear medicine and x-ray findings on the function of the small
      intestine in patients with treated exudative enteropathy].

PMID- 4366663
TI  - [Cytogenetic studies on lymphocytes following irradiation].

PMID- 4366664
TI  - [Behavior of thymidine kinase in irradiated blood lymphocytes after stimulation
      with plant agglutinin].

PMID- 4366665
TI  - [Effects of extracorporeal irradiation on normal and pathological lymhocytes].

PMID- 4366666
TI  - [Cell-tissue changes following small doses of beta-, gamma, x-ray and laser
      radiation].

PMID- 4366667
TI  - [Morphologic changes of the lymphatic system following irradiation].

PMID- 4366668
TI  - Lymphocytopoiesis after irradiation.

PMID- 4366669
TI  - [Radiation effects and function of the reticuloendothelial system (RES)].

PMID- 4366670
TI  - [Changes in the antigenicity of serum albumin after lymph node irradiation].

PMID- 4366671
TI  - [Reciprocal effect of ultraviolet and ionizing radiation on the skin].

PMID- 4366672
TI  - [New methods in the radiologic synchronization of small doses and their
      determination using the impulse cytophotometer].

PMID- 4366673
TI  - [Radiation-hematologic blood picture analysis using impulse cytophotometry].

PMID- 4366674
TI  - [Analysis of lymphoscintigraphy and lymphography with reference to therapeutic
      consequences].

PMID- 4366675
TI  - The pathology of colitis and other inflammatory diseases of the colon.

PMID- 4366676
TI  - [X-ray diagnosis of colitis and other inflammatory diseases of the colon].

PMID- 4366677
TI  - [X-ray morphology of inflammatory colonic diseases secondary to tuberculous
      inflammations with reference to angiographic findings].

PMID- 4366678
TI  - [Clinical aspects of inflammatory colonic diseases with special reference to
      coloscopy].

PMID- 4366679
TI  - [Tropical colonic diseases].

PMID- 4366680
TI  - [Stenoses of the colon descendens due to cobalt-therapy for hypernephroma].

PMID- 4366681
TI  - [Colitis ulcerosa and granulomatosa from surgical viewpoint].

PMID- 4366682
TI  - [Diverticulosis. Diverticulitis from the surgical viewpoint].

PMID- 4366683
TI  - [Irritable colon].

PMID- 4366684
TI  - [A "new" pathognomonic, differential diagnostic sign between ulcerative colitis
      and Crohn's disease].

PMID- 4366685
TI  - [X-ray morphological findings in early and special forms of colitis].

PMID- 4366686
TI  - [Which is the best x-ray method for the determination of ulcerative colitis?].

PMID- 4366687
TI  - [Chronic forms of colitis due to various diseases in the infant and small-child
      age].

PMID- 4366688
TI  - [Acute, life-endangering hemorrhage from the colon in ulcerative colitis and in
      radiation injuries of the colon].

PMID- 4366689
TI  - [Pecularities of inflammatory diseases of the sigmoid colon with reference to
      pharmacoradiography].

PMID- 4366690
TI  - [Physician's performance in the x-ray examination of the colon].

PMID- 4366691
TI  - [Radiological analysis of the disordered colon function in colitis].

PMID- 4366692
TI  - [Early x-ray signs of inflammatory colonic diseases].

PMID- 4366693
TI  - [Colon-transplants in reconstructive surgery of the esophagus].

PMID- 4366694
TI  - [Significance of angiography in the diagnosis of colitis].

PMID- 4366695
TI  - Compact cyclotron neutron dosimetry.

PMID- 4366696
TI  - Neutrons in radiotherapy--yes or no?

PMID- 4366697
TI  - Biological effects of fast neutrons.

PMID- 4366698
TI  - [Clinical experiences in neutron therapy].

PMID- 4366699
TI  - [Neutron-producing instruments for radiotherapy].

PMID- 4366700
TI  - [Neutron therapy unit (15 MeV) in the University Radiology Clinic Hamburg
      Eppendorf].

PMID- 4366701
TI  - [Planned nuclear medicine use of the Heidelberg cyclotron].

PMID- 4366702
TI  - [Diagnosis of salivary gland diseases].

PMID- 4366703
TI  - [Results of radiological after care in surgically treated thyroid neoplasms].

PMID- 4366704
TI  - [Lympho-venous anastomosis in the thoraco-axillary region].

PMID- 4366705
TI  - [Thermography of the lower limb. Comparison of thermography, arteriography,
      venography and lymphography].

PMID- 4366706
TI  - [Studies on the problem of thyrogenic osteopathy (radio-calcium kinetics,
      histomorphometry)].

PMID- 4366707
TI  - [New possibilities in the control of radiation sickness].

PMID- 4366708
TI  - [1st experiences with routine xeroradiography].

PMID- 4366709
TI  - [Use of isotopes for the determination of blood-flow volume in the leg during
      arterial occlusive diseases of the lower limbs].

PMID- 4366711
TI  - [Angiographic localization and pharmacological control of gastrointestinal
      hemorrhages].

PMID- 4366710
TI  - [X-ray criteria for strangulation of the small intestine in the abdominal picture
      without contrast media].

PMID- 4366712
TI  - [Combined radiological diagnosis for the assessment of liver diseases in
      thorotrast-carriers].

PMID- 4366713
TI  - [Technology of television tubes].

PMID- 4366714
TI  - [Physiology of television watching and its limitations].

PMID- 4366715
TI  - [Clinical requirements for the transfer of pictures in x-ray diagnosis].

PMID- 4366716
TI  - [Electronic procedure for modification of the picture content of x-ray exposures
      on the television screen].

PMID- 4366717
TI  - [Demonstration of isotope distribution using electron-ray tubes].

PMID- 4366718
TI  - [Radiation load and radiation protection in the use of television sets].

PMID- 4366719
TI  - [Possibilities in the clarification of details on x-ray pictures using coherent
      light].

PMID- 4366720
TI  - [Television-technical possibilities and their clinical value].

PMID- 4366721
TI  - [Intergrated television-system at the University Clinic Munich--Grosshadern].

PMID- 4366722
TI  - [Use of color-television in x-ray diagnostics].

PMID- 4366723
TI  - [Viewing conditions for transillumination installations].

PMID- 4366725
TI  - [Photography and cinematography off the television screen].

PMID- 4366724
TI  - [Influence of the inhomogeneous background on the possibility of obtaining fine
      structural details of the lung in the x-ray picture for television].

PMID- 4366726
TI  - [Requirements on film quality in motion pictures taken off the television
      screen].

PMID- 4366727
TI  - [Television-regulated tomography and comparison of consequently required
      tomographic technics].

PMID- 4366728
TI  - [Combined endoscopic-radiologic pancreaticography (ERP)].

PMID- 4366729
TI  - [Neuroradiological examination device "Neurocentrix"].

PMID- 4366730
TI  - [Measuring devices for x-ray specifications: guidelines for accelerator
      installations in the medical field].

PMID- 4366731
TI  - [Prerequisites and implementation of an uniform capacity equalizing system in the
      x-ray department of the German Diagnostic Clinic].

PMID- 4366732
TI  - [Prerequisites and implementation of an uniform capacity. Equalizing system in
      nuclear medicine departments or institutes].

PMID- 4366733
TI  - [Organizational procedure during the use of x-ray diagnostics in operating
      rooms].

PMID- 4366734
TI  - [Model of an institute for the medical use of radioisotopes at an University
      Hospital with 2000 beds].

PMID- 4366735
TI  - [Programmed determination of medical achievements, their control and settlement
      in x-ray diagnostic and radiotherapeutic departments].

PMID- 4366736
TI  - [Personal problems in medical-enterprises].

PMID- 4366737
TI  - [Configuration of a system for programmed text-processing in x-ray diagnostics].

PMID- 4366738
TI  - [Cleartext analysis of x-ray data].

PMID- 4366740
TI  - [Programmed assistance in radiographic findings using automatic recording].

PMID- 4366739
TI  - [Reflections on the implementation of a documentation system in x-ray
      diagnostics].

PMID- 4366741
TI  - [Simplification of the medical letter and finding report in nuclear medicine
      using tape-recording operated typewriters].

PMID- 4366742
TI  - [Ethics, ethos and morals; various fundamental considerations].

PMID- 4366743
TI  - [What is ethics?].

PMID- 4366744
TI  - [Everyday ethics].

PMID- 4366745
TI  - [Advances in German nursing education?].

PMID- 4366747
TI  - [Model of a job description for nursing service administration].

PMID- 4366746
TI  - [Structural plan for the reorganization of professional education in nursing;
      Recommendation of the German Hospital Association-proposal].

PMID- 4366748
TI  - [Student-centered education; group work and group dynamics].

PMID- 4366749
TI  - [Mixed parotid tumor with tyrosine crystals].

PMID- 4366750
TI  - [Primary non-obstructive myocardiopathy and progressive external
      ophthalmoplegia].

PMID- 4366751
TI  - [Association of polyglobulia and fibroma. Study of a case].

PMID- 4366752
TI  - Experimental studies on the regulation of myocardial and adipose tissue
      lipoprotein lipase activitites in rat.

PMID- 4366753
TI  - The electron paramagnetic resonance of oxidized clostridial ferredoxins.

PMID- 4366754
TI  - Regulation of fructose, 1,6-bisphosphatase by histidine under gluconeogenic
      conditions.
AB  - Fructose 1,6-bisphosphatase (EC 3.1.3.11) requires a free divalent metal and a
      metal chelate for optimum activity in the neutral pH range. The latter
      requirement can be satisfied by histidine, which appears to function as the
      chelating metabolite in vivo. Under fasting conditions, the concentrations of
      histidine in rabbit liver vary in the range required for activation of fructose
      bisphosphatase, and the enzyme itself is modified so that it becomes more
      responsive to histidine.

PMID- 4366755
TI  - A phosphate-acceptor protein related to parvalbumins in dogfish skeletal muscle.
AB  - A phosphate-acceptor protein was isolated from the skeletal muscle of the Pacific
      dogfish (Squalus acanthias) displaying properties extremely similar to those of
      the parvalbumins, i.e., the low-molecular-weight, soluble, Ca-binding muscle
      proteins found in fish and amphibians. It has the same characteristic UV
      spectrum, strong affinity for calcium, and immunological crossreactivity with
      antibodies against homogeneous dogfish parvalbumin. Although it was isolated in
      three states of aggregation with molecular weights of about 350,000, 75,000, and
      25,000, all species dissociate in Na dodecyl sulfate into subunits of 11,000 and
      13,000 molecular weight. Furthermore, whereas no phosphorylation of parvalbumins
      could be demonstrated under any experimental conditions, the aggregated forms
      could be readily phosphorylated by a cyclic AMP-independent dogfish protein
      kinase, but not by phosphorylase kinase. One acid-stable and base-labile
      phosphate group was introduced per subunit which could be rapidly released by a
      dogfish protein phosphatase, but only very slowly if at all by phosphorylase
      phosphatase. It is speculated that this "phosphate-acceptor protein" might
      represent a physiologically active form of the parvalbumins.

PMID- 4366756
TI  - Pattern of immunoglobulin synthesis and assembly in a human-mouse somatic cell
      hybrid clone.
AB  - Fusion of human peripheral blood lymphocytes, not forming detectable
      immunoglobulins, with mouse myeloma cells (TEPC-15), secreting mouse
      immunoglobulin A with known antibody activity, yielded a somatic cell hybrid
      clone that secreted both human and mouse immunoglobulins. Analysis by sodium
      dodecyl sulfate-polyacrylamide gel electrophoresis indicated that human gamma,
      alpha, and light chains, as well as mouse alpha and light chains, were formed by
      the hybrid cells. To determine whether individual antibody molecules with both
      human and mouse components were secreted, medium from the hybrid cells was
      precipitated first with antibody against mouse immunoglobulin produced in rabbit,
      reduced, and alkylated, and then reprecipitated with antibody against human
      immunoglobulin produced in rabbit. Human gamma, alpha, and light chains were
      detected after electrophoresis of the immunoprecipitates on sodium dodecyl
      sulfate-polyacrylamide gels, indicating that antibody molecules containing both
      human and mouse components were secreted by the hybrid cells. These data indicate
      that this somatic cell hybrid clone synthesized human gamma and alpha heavy
      chains and human light chains, as well as mouse alpha heavy chains and mouse
      light chains. Some of these immunoglobulin components were assembled as hybrid
      antibody molecules.

PMID- 4366758
TI  - Localization of replicating DNA of simian virus 40 in monkey kidney cells.
AB  - Approximately 80-85% of the DNA synthesized by cells infected with simian virus
      40 during a short pulse with [(3)H]thymidine is associated with host nuclear
      membrane components, as defined by the M-band technique. A substantial portion of
      this membrane-associated DNA has been shown to be viral specific by sedimentation
      studies and by DNA.DNA hybridization. Examination of DNA associated and
      unassociated with nuclear M-band by neutral sucrose gradient analysis suggested
      that while replicating DNA of simian virus 40 is attached to the nuclear
      membrane, mature component I DNA of simian virus 40 is released from the membrane
      upon completion of replication.

PMID- 4366757
TI  - Dominance of the senescent phenotype in heterokaryons between replicative and
      post-replicative human fibroblast-like cells.
AB  - In heterokaryons between senescent and young diploid fibroblast-like cells,
      dominance of the former with respect to nuclear DNA synthesis (incorporation of
      [(3)H]thymidine) was demonstrated. For identification of the respective partners,
      double-layer autoradiography was used after the old cells were labeled with
      [(3)H]methionine and the young cells were labeled with [(14)C]thymidine.
      Synchrony of nuclear labeling (i.e., all nuclei in a cell labeled with
      [(3)H]thymidine) was observed in the majority of di- and polykaryons during the
      second and third of three 24-hr periods of labeling with [(3)H]thymidine. The
      results are compatible with either terminal differentiation or error theories of
      clonal senescence.

PMID- 4366760
TI  - Effects of dialyzable transfer factor in patients with breast cancer.
AB  - Five patients with advanced breast cancer were treated with pooled dialyzable
      transfer factor from healthy adult donors. The period of treatment ranged from 21
      to 310 days, the total dose from 20 to 257 ml. Transfer factor did not elicit
      inflammatory or hypersensitivity reactions or detectable formation of antibody to
      itself, nor any hematological or biochemical abnormalities or other side effects.
      Three patients became responsive (by skin test) to tuberculin and/or
      streptococcal antigens. Marked partial regression of the breast cancer, lasting 6
      months, was observed in one patient.

PMID- 4366759
TI  - Lipid binding to the amphipathic membrane protein cytochrome b5.
AB  - The lipid binding properties of the membrane protein cytochrome b(5) (detergent
      extracted from calf liver microsomal preparations) were characterized by studying
      the interaction of spin-labeled lipids (5-, 12-, and 16-doxylstearic acid and 5-
      and 16-doxylphosphatidyl-choline, where doxyl refers to the nitroxide moiety)
      with cytochrome b(5), using electron spin resonance spectroscopy. The intact
      cytochrome b(5) molecule immobilizes all of the lipid spin labels, while the
      segment of cytochrome b(5) released by trypsin does not affect lipid mobility.
      The immobilization of lipid spin labels on the hydrophobic surface of intact
      cytochrome b(5) is not appreciably altered by associating the protein with
      liposomes. Differences in polarity of the lipid binding sites between cytochrome
      b(5) and phospholipid vesicles were also observed. The lipid binding sites on
      cytochrome b(5) are hydrophobic by conventional criteria, but are more polar than
      the interior of fluid phospholipid bilayers.

PMID- 4366761
TI  - Glucose inhibition of adenylate cyclase in intact cells of Escherichia coli B.
AB  - Previous studies in E. coli B have demonstrated an inverse correlation between
      the presence of glucose in the medium and the accumulation of cyclic AMP in the
      medium. This observation could not be explained by the action of glucose as a
      repressor of adenylate cyclase (EC 4.6.1.1) synthesis, as a stabilizer of cyclic
      AMP phosphodiesterase (EC 3.1.4.17) activity, or as a direct inhibitor of
      adenylate cyclase activity in cell-free preparations. The recent development of
      an in vivo assay for adenylate cyclase has provided a basis for further exploring
      the inhibitory action of glucose in intact cells. With this assay it has been
      possible to show that, while glucose does not affect adenylate cyclase in vitro,
      it rapidly inhibits the enzyme activity in intact cells. Extensive metabolism of
      glucose is not required, since alpha-methylglucoside also inhibits adenylate
      cyclase in vivo. When cells are grown on glucose as carbon source, some sugars
      (mannose, glucosamine) substitute for glucose as adenylate cyclase inhibitors
      while others (e.g., fructose) do not. Dose-response studies indicate that low
      concentrations of glucose lead to essentially complete inhibition of adenylate
      cyclase activity while only moderately decreasing intracellular cyclic AMP
      concentrations. The evidence presented suggests that the decreased cellular
      cyclic AMP levels resulting from glucose addition can be accounted for by
      inhibition of adenylate cyclase without any significant effect on cyclic AMP
      phosphodiesterase or the transport of cyclic AMP from the cells to the medium.

PMID- 4366762
TI  - Isolation of the major viral glycoprotein and a putative precursor from cells
      transformed by avian sarcoma viruses.
AB  - Immune precipitation with a monospecific antiserum was employed to study the
      synthesis of the major viral glycoprotein gp85. Labeled gp85 was detectable by
      polyacrylamide gel electrophoresis of immune precipitates prepared from lysates
      of transformed cells which had been labeled for long term with radioactive amino
      acid or fucose. When immune precipitates were prepared from lysates of cells
      pulse-labeled with radioactive amino acid, the bulk of the precipitated counts
      did not appear in gp85 but in a heterogeneous protein fraction with a mean
      molecular weight of approximately 70,000; this fraction has been designated p70.
      If, however, the pulse label was followed by incubation of the cells in medium
      containing excess unlabeled amino acid, the bulk of the precipitated counts
      comigrated with gp85. Similar pulse-labeling experiments with radioactive fucose
      and glucosamine suggested that p70 represents incompletely glycosylated precursor
      to gp85.

PMID- 4366763
TI  - The isolation and characterization of a new iron-sulfur protein from
      photosynthetic membranes.
AB  - A new iron-sulfur protein, distinct from the soluble chloroplast ferredoxin, was
      isolated from chloroplast membranes. The isolated protein, purified to
      homogeneity, had a molecular weight of about 8000 and 4 atoms of iron and 4
      inorganic sulfides per mole. Its absorption spectrum had a broad absorbance band
      in the 400 nm region, a shoulder at approximately 310 nm, and a peak around 280
      nm. The absorbance ratio A(400) to A(280) was 0.55. The electron paramagnetic
      resonance spectrum (measured at 12 degrees K) of the reduced protein was similar
      to that of other reduced iron-sulfur proteins, showing a major resonance line at
      g = 1.94. The isolated protein, when photoreduced by spinach chloroplasts, can in
      turn transfer electrons to mammalian cytochrome c. However, the photoreduced
      protein cannot replace soluble ferredoxin in NADP(+) reduction because of its
      apparent inability to interact with the chloroplast enzyme, ferredoxin-NADP(+)
      reductase. The relation of the isolated iron-sulfur protein to the bound
      ferredoxin that acts as the primary electron acceptor in Photosystem I is
      discussed.

PMID- 4366764
TI  - Regulation of adenylate kinase and creatine kinase activities in myogenic cells.
AB  - The regulation of the specific activities of adenylate kinase (EC 2.7.4.3) and
      creatine kinase (EC 2.7.3.2) in myogenic cell lines is independent of cell
      fusion. The observed increases in enzyme specific activities are cell density
      dependent, and may be further broken down into contributions from an increase in
      enzyme activity per cell and a decrease in protein per cell. Only the former
      appears to be affected by medium conditioning.

PMID- 4366765
TI  - The homopolyadenylate and adjacent nucleotides at the 3'-terminus of 30-40s RNA
      subunits in the genome of murine sarcoma-leukemia virus.
AB  - Adenosine is the major 3'OH-terminal nucleoside of the 60-70S RNA genome of the
      murine sarcoma-leukemia virus, its 30-40S RNA subunits, and the poly(A) segments
      derived by RNase treatment of both RNA species, as determined by periodate
      oxidation-[(3)H]-borohydride reduction. The binding 30-40S RNA to oligo(dT)
      cellulose suggests that most viral RNA subunits contain poly(A). The molecular
      weight of poly(A) derived from viral RNA by digestion with RNase and purified by
      affinity chromatography is 64,000-68,000, as determined by gel electrophoresis.
      From the size of poly(A) and the poly(A) content of viral RNA (1.6%), it is
      estimated that there is about one poly(A) segment for each viral 30-40S RNA
      subunit. The results of 3'-termini labeling with [(3)H]borohydride, in vivo
      labeling with [(3)H]adenosine, and base composition of [(32)P]poly(A) indicate
      that a homopoly(A) segment is located at the 3'-end of a 30-40S RNA subunit. The
      homogeneous poly(A) segments isolated from RNase T1 digests of 60-70S [(32)P]RNA
      consist of one cytidylate, one uridylate, and about 190 adenylate residues, while
      those isolated from RNase A digests consist exclusively of adenylate residues.
      These results indicate that -G(C,U)A(190)A(OH) is the 3'-terminal nucleotide
      sequence of the viral 30-40S RNA subunits.

PMID- 4366767
TI  - Short-term binding and hydrolysis of cyclic 3':5'-adenosine monophosphate by
      aggregating Dictyostelium cells.
AB  - Transient binding of cyclic AMP to aggregating cells of Dictyostelium discoideum
      was measured under cyclic GMP excess in order to inhibit cyclic AMP hydrolysis by
      cell-bound phosphodiesterase. Cyclic GMP extended the period of half-maximal
      cyclic AMP binding from less than 5 sec to 1-2 min. With the same time course as
      bound cyclic AMP was released from the cells, labeled 5'-AMP appeared in the
      medium. Specificity, kinetics, and developmental regulation suggest that the
      cyclic AMP-binding sites exposed in living cells are identical with receptor
      sites for the chemotactic response. The functioning of the cyclic AMP
      receptor/phosphodiesterase system and its formal similarity with the synaptic
      acetylcholine-receptor/esterase system are discussed.

PMID- 4366766
TI  - Induction of a lactogenic receptor in rat liver: influence of estrogen and the
      pituitary.
AB  - A receptor exists in female rat liver with high specificity for lactogenic
      hormones. Previous work showed the receptor level increased at the time of
      puberty in female but not male animals. Pregnancy caused a further substantial
      increase. Here we show that estrone (50 mug/day) administration to male rats
      induced a 10- to 30-fold increase in specific binding of ovine prolactin and
      human growth hormone after 8-12 days with a significant increase first seen after
      4 but not 2 days of injection. In females, this regimen increased binding to
      pregnancy levels. In prepuberal (20-days-old) male and female rats, estrone was
      also markedly stimulatory. The binding sites for ovine prolactin and human growth
      hormone were of high affinity in liver membranes from both female and estrone
      treated male rats (K(a) = 0.6 to 1.4 x 10(9) M(-1)). Estrone and estradiol were
      equally effective in inducing the lactogenic receptor. Estriol (50 mug/day),
      progesterone (500 mug/day), human placental lactogen (1 mg/day), and testosterone
      (100 mug/day) were without influence. Hypophysectomy drastically decreased the
      levels of lactogenic receptor in mature female rats, and estrogen treatment
      failed to restore receptor levels to normal. Hypophysectomized male rats were
      also unresponsive to estrogen. Throughout these studies the specific binding of
      (125)I-labeled insulin remained relatively constant. This work demonstrates
      estrogen induction of a lactogenic receptor. The pituitary gland appears to have
      a critical, though presently undefined, role in the induction process.

PMID- 4366768
TI  - Effect of poliovirus double-stranded RNA on viral and host-cell protein
      synthesis.
AB  - Cell-free protein-synthesizing systems that initiate on endogenous messenger RNA
      have been developed from uninfected and poliovirus-infected HeLa cells.
      Poliovirus double-stranded RNA is an effective inhibitor of protein synthesis in
      these extracts, and both cell-directed and virus-specific protein synthesis are
      equally sensitive to the inhibitory action of double-stranded RNA. The
      concentrations of double-stranded RNA required for inhibition are not achieved in
      the infected cell at early times after infection when host-cell shut-off occurs,
      but rather are achieved only late in infection when virus-specific protein
      synthesis begins to decline. This indicates that double-stranded RNA does not act
      as a direct agent to inhibit host cell protein synthesis following infection by
      poliovirus. The possible significance of inhibition by double-stranded RNA of
      poliovirus-specific protein synthesis is discussed.

PMID- 4366769
TI  - Kinetic properties and electron paramagnetic resonance spectra of the nitric
      oxide derivative of hemoglobin components of trout (Salmo irideus).
AB  - The binding of nitric oxide to hemoglobin components of trout (Salmo irideus),
      i.e., Hb trout I and Hb trout IV, has been studied by optical and electron
      paramagnetic resonance spectroscopy. Kinetic studies show that the Root effect in
      Hb trout IV is operative also for NO, since a large increase in the dissociation
      velocity constant (j(4)) is observed as the pH is decreased below 7. Moreover,
      the time course of the displacement of NO by CO is heterogeneous, suggesting that
      alpha and beta chains may have different j(4) values. Low-temperature X-band
      electron paramagnetic resonance spectra have been recorded with Hb trout I and IV
      saturated with NO at different pH values. The spectra of Hb trout IV are strongly
      pH-dependent. The high-pH form (pH 8.1) shows axial symmetry and no resolved
      hyperfine splitting, while the low-pH form is rhombic with a hyperfine splitting
      of 6.5 G in the g(z) region. The latter form reflects a more distorted site with
      a more significant delocalization of the unpaired electron on the proximal
      histidine; both features indicate a destabilization of the ligand binding at low
      pH. On the other hand, spectra of Hb trout I are axial at both pH values, with
      hyperfine splitting of 16.5 G, indicating that the site is not distorted and
      interacts with the ligand very strongly at either pH.

PMID- 4366770
TI  - Phosphate metabolism in intact human erythrocytes: determination by phosphorus-31
      nuclear magnetic resonance spectroscopy.
AB  - Whole human blood was examined by (31)P nuclear magnetic resonance spectroscopy.
      Individual phosphates (alpha,beta,gamma) of ATP were identifiable, and two
      microenvironments appeared to be present for this molecule. When sequential
      recordings of freshly collected blood were made, 2,3-diphosphoglycerate was
      observed to decrease in association with a concomitant increase in inorganic
      orthophosphate. When aged cells containing little 2,3-diphosphoglycerate were
      incubated in the presence of inosine and pyruvate, 2,3-diphosphoglycerate
      formation could be demonstrated. These results show that cellular metabolism can
      be recorded directly in intact cells by (31)P nuclear magnetic resonance.

PMID- 4366771
TI  - Cholera toxin mimics melanocyte stimulating hormone in inducing differentiation
      in melanoma cells.
AB  - Cholera toxin (choleragen) and melanocyte stimulating hormone alter within hours
      the morphology of melanoma cells in culture, and they slow the growth of serum
      stimulated cells. After 7-10 days, cells exposed to choleragen or hormone show
      increased size and a fibroblastic growth pattern. Tyrosinase (EC 1.14.18.1;
      monophenol monooxygenase) activity increases after 3 days in the presence of 10(
      8) M hormone or 10(-10) M choleragen. Binding studies with (125)I-labeled
      choleragen indicate that although a melanoma cell can bind a maximum of 10(6)
      molecules of cholera toxin, only about 4000 binding sites must be occupied to
      achieve maximum stimulation of tyrosinase activity. Melanocyte stimulating
      hormone and choleragen probably have different membrane-binding sites. After
      exposure to choleragen for 5 min, membrane adenylate cyclase (EC 4.6.1.1)
      activity increases dramatically upon further incubation of intact cells for
      several hours at 37 degrees and falls slowly to basal values over a period of
      more than 10 days. Hormone stimulation of adenylate cyclase is rapidly reversed
      by washing the cells, but subsequent restimulation of cyclase by the hormone is
      impaired. These studies indicate that cAMP mediates the effects of melanocyte
      stimulating hormone on growth and morphology as well as on tyrosinase activity.
      Cholera toxin may permanently activate the available adenylate cyclase molecules,
      and the protracted decay of stimulation that follows may reflect the biological
      turnover of adenylate cyclase molecules in these cells.

PMID- 4366773
TI  - The mechanism of viral replication. Structure of replication complexes of
      encephalomyocarditis virus.
AB  - The structure of the purified replicative intermediate of encephalomyocarditis
      virus was determined by electron microscopy. Approximately 80% of the replicative
      intermediate complexes were characterized by a filament of double-stranded RNA of
      widely variable length, which had a "bush" of single-stranded RNA at one end. In
      many examples one or more additional single-stranded bushes were appended
      internally to the double-stranded RNA filament. These results support the view
      that before deproteinization, replicative intermediate contains little if any
      double-stranded RNA.

PMID- 4366774
TI  - Acquirement of fetal properties in hepatoma on glutathione metabolism.

PMID- 4366772
TI  - Demonstration of dopamine-sensitive adenylate cyclase in malignant neuroblastoma
      cells and change in sensitivity of adenylate cyclase to catecholamines in
      "differentiated" cells.
AB  - Adenylate cyclase (EC 4.6.1.1) activity was stimulated by low concentrations of
      dopamine and apomorphine, but not by low concentrations of norepinephrine in
      homogenates of malignant mouse neuroblastoma cells. In cyclic AMP-induced
      "differentiated" cells, dopamine concentration required for a maximal increase in
      adenylate cyclase activity was about 10-fold less than that required for a
      similar increase in control cells, and norepinephrine-sensitive adenylate cyclase
      activity became apparent at low norepinephrine concentrations. The
      pharmacological properties of dopamine-sensitive adenylate cyclase were different
      from those of norepinephrine-sensitive enzyme. For example, dopamine-stimulated
      adenylate cyclase activity was markedly reduced by low concentrations of
      haloperidol and phentolamine, whereas norepinephrine-stimulated enzyme activity
      required higher concentrations of these blocking agents for a similar amount of
      inhibition. Norepinephrine-stimulated enzyme activity was markedly blocked by low
      concentrations of propranolol, whereas dopamine-stimulated enzyme activity
      required a much higher concentration of this blocking agent for a similar amount
      of inhibition. Low concentrations of isoproterenol increased adenylate cyclase
      activity in malignant cells, but in "differentiated" cells even a high
      concentration failed to do so. The fact that dopamine and norepinephrine produced
      an additive stimulatory effect on adenylate cyclase activity suggests that they
      interact at different receptor sites. This suggestion is further supported by the
      observation that the combination of prostaglandin E(1) and norepinephrine
      produced an additive stimulatory effect of enzyme activity. The observation that
      the effects of dopamine and prostaglandin E(1) are not additive, coupled with the
      observation that a low concentration of phentolamine blocked the effect of
      prostaglandin E(1), suggests that these two agents may interact at a common site.

PMID- 4366775
TI  - Hormonal regulation of hepatic and jejunal formiminotransferase activity in man
      and rat.

PMID- 4366776
TI  - Correlations between the enzymatic activities and the factors active on blood
      coagulation and platelet aggregation from the venom of Vipera aspis.

PMID- 4366777
TI  - SV40 nucleoprotein complex activity unwinds superhelical turns in SV40 DNA.

PMID- 4366778
TI  - Binding of concanavalin A and ricin to synaptic junctions of rat brain.

PMID- 4366779
TI  - Toxins of Vibrio cholerae and Escherichia coli stimulate adenyl cyclase in rat
      fat cells.

PMID- 4366780
TI  - Constitutivity of the HCG-receptor protein in the testis of rat and man.

PMID- 4366782
TI  - The effect of angiotensin upon the vasculature of the isolated perfused rat
      kidney.

PMID- 4366781
TI  - Release of cyclic AMP from rat superior cervical ganglia after stimulation of
      synthesis in vitro.

PMID- 4366783
TI  - Meiotic drive in tn-bearing mouse spermatozoa: a relationship between aerobic
      respiration and transmission frequency.

PMID- 4366784
TI  - [Effect of imuran on enzymatic activity of peripheral blood leukocytes in
      rheumatoid arthritis].

PMID- 4366785
TI  - [Control of ACTH secretion. Present diagnosis of Cushing's syndrome and adrenal
      insufficiency].

PMID- 4366786
TI  - The somatomedins: a family of insulinlike hormones under growth hormone control.

PMID- 4366787
TI  - MSH, cyclic AMP, and melanocyte differentiation.

PMID- 4366788
TI  - Interpreting the failures to confirm the depression of cerebellar Purkinje cells
      by cyclic AMP.

PMID- 4366789
TI  - D(--)-lactic acid and d(--)-lactate dehydrohgenase in octopus spermatozoa.
AB  - The spermatozoa of Octopus dofleini martini produce anaerobically D(-)-lactic
      acid and possess a very active D(-)-lactate dehydrogenase. In this respect, while
      resembling certain microorganisms, they differ strikingly from mammalian
      spermatozoa which produce L(+)-lactic acid and contain L(+)-lactate
      dehydrogenase.

PMID- 4366790
TI  - The spectrum of antibacterial activity of human amniotic fluid determined by
      scanning electron microscopy.

PMID- 4366791
TI  - Serum estradiol-17beta and serum human chorionic gonadotropin in patients with
      hydatidiform moles.

PMID- 4366793
TI  - Quantitation of the lecithin-sphingomyelin ratio in amniotic fluid by a simple
      charring method.

PMID- 4366792
TI  - Progesterone concentrations in the sera of patients with intact and aborted
      hydatidiform moles.

PMID- 4366794
TI  - Respiratory movements in fetal rhesus monkeys.

PMID- 4366795
TI  - Studies on the luteinizing hormone- and follicle-stimulating hormone-releasing
      mechanism in the testicular feminization syndrome. Hypothalamic-pituitary
      responsiveness to clomiphene, luteinizing hormone-releasing hormone, gonadectomy,
      and sexual steroids.

PMID- 4366797
TI  - Cyclic AMP, ATP and cell contact.

PMID- 4366796
TI  - Viral teratogenesis: a review with experimental and clinical perspectives.

PMID- 4366798
TI  - Correlations between plasma ACTH concentrations and breathing movements in foetal
      sheep.

PMID- 4366799
TI  - Herpes simplex viruses: discrimination of types and correlation between different
      characteristics.

PMID- 4366800
TI  - Mink cell line Mv 1 Lu (CCL 64). Focus formation and the generation of
      "nonproducer" transformed cell lines with murine and feline sarcoma viruses.

PMID- 4366801
TI  - The nucleotide sequence of chicken 5S ribosomal RNA.

PMID- 4366802
TI  - Potentiated acid 1,5 pentanedial solution--a new chemical sterilizing and
      disinfecting agent.

PMID- 4366803
TI  - Zonal electrophoresis and isoelectric focusing of proteins and virus particles in
      density gradients of small volume.

PMID- 4366804
TI  - Analysis of hydroxyproline and hydroxylysine by gas chromatography.

PMID- 4366805
TI  - The steroid specificity of the estrogen-receptor of human breast carcinoma.

PMID- 4366806
TI  - Mechanism of estrogen action--independence of several responses of the rat uterus
      from the early increase in adenosine 3',5'-cyclic monophosphate.

PMID- 4366808
TI  - Involvement of the anticodon region of Escherichia coli tRNAGln and tRNAGlu in
      the specific interaction with cognate aminoacyl-tRNA synthetase. Alteration of
      the 2-thiouridine derivatives located in the anticodon of the tRNAs by BrCN or
      sulfur deprivation.

PMID- 4366807
TI  - Quantitative histologic distribution of adenosine-3',5'-monophosphate in the rat
      stomach. Improved procedure for the luminescence assay.

PMID- 4366810
TI  - Nucleases in HeLa cell nucleoplasm and nucleoli.

PMID- 4366809
TI  - Ribosomal RNA homologies in flowering plants: comparison of the nucleotide
      sequences in 5.8-S rRNA from broad bean, dwarf bean, tomato, sunflower and rye.

PMID- 4366811
TI  - [Separation and purification of Robinia lectin and concanavalin A binding sites
      from the surface of normal and transformed hepatic cells (Zajdela's hepatoma)
      (author's transl)].

PMID- 4366812
TI  - Lateral phase separations in Escherichia coli membranes.

PMID- 4366813
TI  - Tumors of the submandibular gland.

PMID- 4366814
TI  - Structural differences in the adenylate kinase enzymes.

PMID- 4366815
TI  - Activity of microsomal enzymes in the livers of rats fed rapeseed oil.

PMID- 4366816
TI  - Pathology of ulcerogenic and diarrheogenic tumors of the pancreas.

PMID- 4366817
TI  - Studies on the stability of rat liver D-glucose-6-phosphate phosphohydrolase (EC
      3.1.3.9).

PMID- 4366818
TI  - The effect of partial degradation of mitochondrial phospholipids by phospholipase
      A on the temperature dependence of succinate-cytochrome c reductase and
      cytochrome c oxidase.

PMID- 4366820
TI  - [Repair of esophageal mouth stenosis secondary to previous operative section of
      the esophagus].

PMID- 4366821
TI  - [Giant sub-cardial ulcer. Therapeutic failure requiring total gastrectomy].

PMID- 4366819
TI  - Uptake and accumulation of purine bases by stationary yeast cells pretreated with
      glucose.

PMID- 4366822
TI  - [Reticulosarcoma of the stomach with invasion of the liver, spleen and bone
      marrow].

PMID- 4366823
TI  - [Lithiasis of the choledocus formed upon ligation material].

PMID- 4366825
TI  - [Lithiasis of Wirsung's duct discovered by retrograde catheterization].

PMID- 4366824
TI  - [Malignant tumors of the liver in infants].

PMID- 4366826
TI  - [Splenic rupture and chronic pancreatitis].

PMID- 4366827
TI  - [Splenomegaly and ectopic spleen].

PMID- 4366828
TI  - [Lymphosarcoma of the splenic region].

PMID- 4366830
TI  - [Localized necrosis of the small intestine after arteriography].

PMID- 4366829
TI  - [Calcified appendicular mucocele].

PMID- 4366831
TI  - [The 1832 cholera epidemic in the prisons of Paris].

PMID- 4366832
TI  - Regulation of membrane lipid fluidity in Acholeplasma laidlawii: effect of
      carotenoid pigment content.

PMID- 4366833
TI  - Partitioning turkey blood plasma and egg yolk lipoproteins using agarose gel.

PMID- 4366834
TI  - Hematological responses associated with resistance to Rous sarcomas in four
      strains of chickens.

PMID- 4366835
TI  - Estradiol mustard (NSC-112259) and phenester (NSC-116785): possible mediation of
      action by estrogen binding protein.

PMID- 4366837
TI  - [Diffuse xanthogranulomatous pyelonephritis in children. Report of 6 new cases].

PMID- 4366836
TI  - [Comparative biochemical analysis of midgut extracts of the first-stage larvae of
      warble flies].

PMID- 4366838
TI  - [Limits of the surgical treatment of kidney cancer. Special problems of
      nephroblastoma in children].

PMID- 4366839
TI  - [Bilateral renal angiofibromyolipoma and Bourneville's tuberous sclerosis].

PMID- 4366840
TI  - Chemistry of technetium 99m.

PMID- 4366841
TI  - [Letter: Gonadotropin pituitary inhibition test. New data in the detection and
      the biological surveillance of trophoblastic tumors in both sexes].

PMID- 4366842
TI  - [Letter: Hemochromatosis with positive alpha-feto-protein. A further case].

PMID- 4366844
TI  - Analysis of the relationship between 99mTc-Sn-polyphosphate and 99mTc-Sn
      pyrophosphate.

PMID- 4366843
TI  - Effect of caffeine on the neuromuscular junction of the frog, and its relation to
      external calcium concentration.

PMID- 4366845
TI  - The diagnostic value of bronchial washing in lung cancer.

PMID- 4366846
TI  - A new electrophoretic technique for mouse, human, and Chinese hamster
      galactokinase.

PMID- 4366848
TI  - Intraocular and optic nerve sheath hemorrhage in cases of sudden intracranial
      hypertension.

PMID- 4366849
TI  - Ganglion of the peroneal nerve. Report of two cases.

PMID- 4366847
TI  - Blood loss and factors affecting pulmonary antibacterial defenses.

PMID- 4366851
TI  - Induction of alkaline phosphatase activity by dibutyryl adenosine 3':5'-cyclic
      monophosphate in aneuploid rat liver cells.

PMID- 4366853
TI  - Ultrastructural localization of SV40 viral DNA in cells, during lytic infection,
      by in situ molecular hybridization.

PMID- 4366852
TI  - Some effects of 5-bromodeoxyuridine on polyoma-transformed mouse cells.

PMID- 4366854
TI  - Ribosomal protein differences between animal cells.

PMID- 4366850
TI  - The Mongolian gerbil as a model for lead toxicity. I. Studies of acute poisoning.
AB  - Mongolian gerbils fed diets containing lead acetate maintained body weight
      comparable to gerbils fed the same diet without added lead. Intranuclear lead
      inclusion bodies in epithelial cells of the proximal convoluted tubules of the
      kidney were first observed at 4 weeks, and increased in number to about 50 per
      high power field at 12 weeks. At this time, a corticomedullary area of empty
      appearing tubules was prominent. Transmission electron microscopy confirmed the
      increase in number and size of nuclear lead inclusion over the 12-week period.
      Cytoplasmic changes observed in proximal tubule cells containing lead inclusions
      were considered indicative of acute lethal injury. Distinct cytoplasmic fibrillar
      structures, first apparent at 8 weeks, were present in some proximal tubular
      lining cells and strongly resembled newly formed intranuclear lead inclusions.
      After 12 weeks, the total amount of lead present in the gerbil kidney was four to
      six times greater than that in rat kidney as determined by atomic absorption
      spectrophotometry. A hypothesis has been formulated that relates the more
      efficient nephron of the gerbil kidney to the rapid and extensive development of
      intranuclear inclusion bodies and the greater accumulation of total lead.

PMID- 4366855
TI  - A diseases of Sokoto goats resembling "peste des petits ruminants".

PMID- 4366856
TI  - A hospital's support systems for chronic patients living in the community.

PMID- 4366857
TI  - Holding tea groups: a home visiting program for chronic schizophrenics.

PMID- 4366858
TI  - Boerum Hill: a private long-term residential program for former mental patients.

PMID- 4366859
TI  - Inhibitory effects in the cuneate nucleus produced by vago-aortic afferent
      fibers.

PMID- 4366860
TI  - Disynaptic corticospinal effects in forelimb motoneurones in the cat.

PMID- 4366861
TI  - [Benign mesenchymal mixed tumor (angiofibromyolipoma) of the cervix uteri].

PMID- 4366863
TI  - [10 keywords for ethics in the nursing profession].

PMID- 4366862
TI  - Effect of prolonged alcohol administration on calcium transport in heart muscle
      of the dog.

PMID- 4366865
TI  - [Ethical principles--critically examined].

PMID- 4366864
TI  - [Professional ethics in nursing education: new dimensions for an auxiliary
      subject].

PMID- 4366867
TI  - Perthes-like changes in the syndrome of caudal regression.

PMID- 4366868
TI  - [Classification of hyperlipoproteinemia. II. Distribution principle of
      hyperlipoproteinemias according to Fredrickson et al. correlated with clinical
      dermatological possibilities].

PMID- 4366866
TI  - [Disease-induced behavior changes in patients. From a nurse's viewpoint].

PMID- 4366869
TI  - Ochratoxin A, an inhibitor of mitochondrial transport systems.

PMID- 4366870
TI  - Virus encephalitis: pathogenesis in the immature brain.

PMID- 4366871
TI  - [Actions induced by urea and guanidine on xanthine dehydrogenase].

PMID- 4366872
TI  - Some chemical aspects of dose-response relationships in alkylation mutagenesis.

PMID- 4366873
TI  - Caffeine-induced enhancement of chromosome damage in human lymphocytes treated
      with methyl-methanesulphonate, mitomycin C and X-rays.

PMID- 4366874
TI  - [Blood protein electrophoresis in patients with lesions of the peripheral nervous
      system].

PMID- 4366875
TI  - [Quantitative determination of free silica in dust samples by using infrared
      spectroscopy].

PMID- 4366876
TI  - Cytomegalovirus infection and sudden death in infants.

PMID- 4366877
TI  - Early eruption of deciduous and permanent teeth: a case report.

PMID- 4366878
TI  - A modified gas chromatographic method for lactate analysis.

PMID- 4366879
TI  - Identification of a vasopressin-neurophysin and of an oxytocin-neurophysin in
      man.

PMID- 4366880
TI  - Effects of neurogenic and systemic stresses on hypothalamic and adenohypophysial
      cAMP content.

PMID- 4366882
TI  - Lecithin:cholesterol acyltransferase and plasma proteins in liver diseases.

PMID- 4366881
TI  - Platelet glucose-6-phosphatase activity in patients with von Gierke's disease and
      their parents.

PMID- 4366883
TI  - The binding of indocyanine green and other organic anions to serum proteins in
      liver diseases.

PMID- 4366884
TI  - [Effects of dibutyryl-cyclic AMP and theophylline on cells separated from
      cultured cerebral hemispheres].

PMID- 4366885
TI  - [Experimental herpetic infection in newborn rats].

PMID- 4366886
TI  - Investigations on the oncogenic activity for the chick embryo of ribonucleic acid
      (RNA) extracted from fowl sarcoma induced by the Carr strain (Zilber) of Rous
      virus.

PMID- 4366887
TI  - Association between production of infectious virus and chromosomal aberrations in
      carcinomatous human cells (HeLa) persistently infected with Papova virus SV40.

PMID- 4366888
TI  - Mitochondrial functions under hypoxic conditions. The steady states of cytochrome
      c reduction and of energy metabolism.

PMID- 4366889
TI  - The effect of temperature on the primary reaction of chloroplast photosystem II.
      Evidence for a temperature-dependent back reaction.

PMID- 4366890
TI  - Identification of ubiquinone as the secondary electron acceptor in the
      photosynthetic apparatus of Chromatium vinosum.

PMID- 4366891
TI  - Light activation of phosphodiesterase activity in retinal rod outer segments.

PMID- 4366892
TI  - EPR studies by 57Fe isotopic substitution on the nature of an unknown electron
      acceptor in Azotobacter vinelandii phosphorylating particles.

PMID- 4366893
TI  - The synthesis of 3-deoxy-4-O-methyl-D-arabino-2-heptulosonic acid and its
      behaviour in the Warren reaction.

PMID- 4366894
TI  - Studies on dextrans and dextranases. XI. The structure of a dextran elaborated by
      Leuconostoc mesenteroides NRRL B-1299.

PMID- 4366895
TI  - A synthesis of (plus or minus)-myo-inositol 1-phosphate.

PMID- 4366896
TI  - Alkaline sucrose gradient sedimentation studies of DNA from HeLa S3 cells exposed
      to methyl methanesulphonate or methylazoxymethanol acetate.

PMID- 4366897
TI  - The determination of metallic elements in wastes and waters with the graphite
      furnace.

PMID- 4366898
TI  - Using primates in medical reseach. 2. Recent comparative research. Cancer--a
      general review.

PMID- 4366899
TI  - Monkey cell cultures in virology.

PMID- 4366900
TI  - Using primates in medical research. 2. Recent comparative research. Communicable
      diseases: hazards for man and models for research.

PMID- 4366901
TI  - Smallpox and monkeypox in primates.

PMID- 4366902
TI  - Using primates in medical research. 1. Husbandry and technology. New World
      monkeys.

PMID- 4366904
TI  - Trophic functions of the neuron. VI. Other trophic systems. Neurotrophic
      regulation at the neuromuscular junction.

PMID- 4366903
TI  - Brain and meningeal infections in children. Radiological considerations.

PMID- 4366905
TI  - Trophic interactions in the mammalian central nervous system.

PMID- 4366906
TI  - Aspects of the geologic history of seawater.

PMID- 4366908
TI  - Some properties of embryonic mitochondria of the loach.

PMID- 4366909
TI  - The relationship between chromosomal aberrations, survival and DNA repair in
      tumour cell lines of differential sensitivity to X-rays and sulphur mustard.

PMID- 4366907
TI  - Biomolecules from HCN.

PMID- 4366910
TI  - [Role of cyclic adenosine monophosphate in phosphorization of histone F1
      thymocytes].

PMID- 4366911
TI  - [Various cytochemical and ultrastructural problems of the pancreatic islands of
      Langerhans].

PMID- 4366913
TI  - [Problem of storage and synaptic processes in the brain].

PMID- 4366912
TI  - [Granular-cell tumor of the third ventricle of the brain. Clinical findings,
      light and electron microscopy].

PMID- 4366914
TI  - Persistence of Adenovirus 5 in guinea pigs.
AB  - One intracardiac inoculation of adenovirus 5 in guinea pigs leads to virus
      persistence in different organs, viz., 5 days in lungs and liver, 14 days in
      blood and lymph nodes, and 56 days or more in the spleen. After cultivation of
      tissue cells for 1 week, virus was recovered from blood, lymph nodes, or spleen
      lymphocytes, but virus could be detected directly in cells only when organs were
      removed within 48 h of inoculation. To determine how the virus persisted in low
      concentrations and as a latent infection, spleens were primarily selected for
      study by three techniques: homogenization of spleens, suspended Maitland fragment
      cultures, and in vitro cultivation of spleen cells. The last procedure showed
      virus in fibroblast-like cells (probably macrophages or reticuloendothelial
      cells) for 56 days after infection of guinea pigs. With other methods, the virus
      was found only within the first 2 days after inoculation.

PMID- 4366915
TI  - In vitro cellular immunity to unrelated pathogens in chickens infected with
      fowlpox virus.
AB  - Peritoneal macrophages recovered from chickens 15 to 20 days after inoculation
      with fowlpox virus and showing a delayed hypersensitivity reaction against
      fowlpox antigens demonstrated an enhanced antimicrobial effect against fowlpox
      virus as well as unrelated viruses and bacteria. Inoculation of normal chicken
      macrophage cultures with fowlpox virus resulted in approximately a 200-fold
      increase in virus titer by 96 h, whereas the virus showed less than a fourfold
      increase in macrophage cultures from fowlpox-immune chickens. Similarly, the
      titer of Newcastle disease virus increased by more than 1 log in cultures of
      normal macrophages, whereas the titer decreased by approximately 1 log after
      infection of fowlpox-immune macrophages. Vaccinia, vesicular stomatitis, and
      herpes simplex viruses, which are not natural pathogens of chickens, failed to
      replicate in cultures of either normal or fowlpox-immune macrophages. By using
      Salmonella gallinarum, it was further demonstrated that the antimicrobial
      activity of fowlpox-immune macrophages encompassed not only nonspecific viruses
      but also bacteria. Infection of normal macrophages with Salmonella resulted in
      intracellular replication of the organism between 0 and 24 h as determined by
      microscope examination and viable bacteria counts. In contrast, cultures of
      fowlpox-immune macrophages failed to show an increase in intracellular organisms
      and showed a marked decrease in viable bacteria. In conclusion, these studies
      clearly showed that cellular immunity, previously demonstrated in mammalian
      species, develops in chickens after infection with fowlpox virus.

PMID- 4366916
TI  - Reactivity of envelope, capsid, and soluble antigens of Herpesvirus hominis types
      1 and 2 in the indirect hemagglutination test.
AB  - Envelope, capsid, and soluble antigens of Herpesvirus hominis (HVH) types 1 and 2
      were compared to crude antigens (disrupted HVH-infected cells) for potency, type
      specificity, and diagnostic value in the indirect hemagglutination (IHA) test.
      The envelope appeared to be the predominant component reacting in the IHA test,
      but recurrent HVH infections increased the reactivity of human sera with capsid
      antigens. The soluble antigens reacted in the IHA test with HVH immune animal
      sera, but very few convalescent-phase human sera showed reactivity with soluble
      antigens. Overall, none of the subunit antigens showed greater type-specificity
      than did crude antigens in IHA tests with immune animal or convalescent-phase
      human sera. Recurrent infections with type 1 or type 2 viruses tended to broaden
      heterotypic reactivity of the patients' sera with both crude and subunit
      antigens, even in patients showing only a single type of antibody by IHA
      inhibition. Subunit antigens were no more sensitive than crude antigens in
      demonstrating significant IHA antibody titer rises for serodiagnosis of
      herpesvirus infections, and they generally had to be used at lower working
      dilutions than crude antigens.

PMID- 4366917
TI  - Production of chemotactic factor and lymphotoxin by human leukocytes stimulated
      with Herpes simplex virus.
AB  - Peripheral blood leukocytes (PBL) of 41 subjects were tested for their ability to
      be stimulated by herpes simplex virus antigens as measured by [(3)H]thymidine
      incorporation and lymphokine production (i.e., lymphocyte-derived chemotactic
      factor and lymphotoxin). The PBL of seronegative subjects failed to respond to
      viral antigens as measured by stimulation or lymphokine production. In contrast,
      PBL from seropositive subjects without clinical lesions of herpes labialis were
      stimulated by herpes simplex virus antigens and produced lymphokines. PBL from
      seropositive patients with clinical lesions of herpes labialis also produced
      lymphokines, but [(3)H]thymidine incorporation was slightly depressed. These
      findings suggest that lymphocytes from patients with a recent herpes simplex
      virus infection may respond less vigorously to in vitro stimulation by herpes
      antigens, but our study fails to show any basic defect in the responsiveness of
      the lymphocytes to account for recurrent herpetic episodes.

PMID- 4366918
TI  - Oxygen uptake by Treponema pallidum.
AB  - Virulent Treponema pallidum has been shown to consume O(2) at a rate similar to
      that of the known aerobic spirochaete, Leptospira. Such O(2) uptake is cyanide
      sensitive, indicating a functioning cytochrome oxidase. Inhibition of O(2) uptake
      by azide, chlorpromazine, and amytal further suggests a functioning electron
      transport system for the oxidation of nicotinamide adenine dinucleotide (reduced)
      to O(2). Evidence is consistent with the probability that this terminal electron
      transport system is coupled to oxidative phosphorylation. The potential
      significance of these findings is discussed.

PMID- 4366919
TI  - Escherichia coli enterotoxin-induced steroidogenesis in cultured adrenal tumor
      cells.
AB  - A heat-labile, Pronase-sensitive factor has been partially purified from cell
      free culture filtrates of enterotoxigenic Escherichia coli. The partially
      purified factor contains both protein and carbohydrate moieties and appears to be
      E. coli enterotoxin (ECT). ECT binds to cultured adrenal tumor cells rapidly and
      irreversibly leads to adenosine 3', 5'-cyclic monophosphate formation and
      steroidogenesis after a 60-min lag phase. Further studies indicate that it
      interacts with the cholera toxin receptor site on adrenal cells rather than the
      adrenocorticotropin receptor to activate adenyl cyclase. Mixed gangliosides block
      stimulation of steroidogenesis in response to both E. coli and cholera
      enterotoxin. In contrast to adrenocorticotropin, ECT has no additive effect on
      cholera toxin-induced steroidogenesis. The protein moiety of ECT is similar to
      cholera enterotoxin because horse serum anticholeragenoid prevented stimulation
      of steroidogenesis by either enterotoxin. Cultured adrenal cells provide a
      quantitative assay system that has facilitated the purification and
      characterization of E. coli enterotoxin.

PMID- 4366920
TI  - Comparison of techniques and immunoreagents used for indirect immunofluorescence
      and immunoperoxidase identification of enteroviruses.
AB  - Peroxidase-conjugated antibodies were found to be as sensitive as those
      conjugated to fluorescein-isothiocyanate (FITC) for identification of selected
      enterovirus types by the indirect technique. Peroxidase conjugates, however, were
      found to give fewer nonspecific reactions. The reasons for the higher specificity
      of the immunoperoxidase technique appear to be related to the relative size,
      charge, and uniformity of the preparations. Monomers of peroxidase-conjugated
      globulin are larger than those of FITC conjugates, but the latter readily form
      aggregates. This was shown by chromatography on Sepharose 6B columns: various
      FITC-conjugated globulins eluted before those conjugated to peroxidase and before
      (125)I-labeled immunoglobulin G. The net charge of the conjugates was determined
      by adsorption to ion-exchange columns. FITC-labeled globulins had a negative net
      charge, eluting at pH 5.1 from diethylamino-ethyl-Sephadex A-50 columns.
      Peroxidase conjugates were not retained by either cationic or anionic exchangers
      at pH values ranging from 4.0 to 10.5. Further, the fluorescein/protein ratios of
      FITC conjugates from different commercial sources and of those prepared in the
      laboratory were found to be variable; higher fluorescein/protein ratios (>2:1)
      give a higher degree of nonspecific reactions, whereas the peroxidase/protein
      ratio does not appear to affect specificity. These characteristics of peroxidase
      conjugates make the immunoperoxidase technique easier to standardize and more
      reliable for enterovirus identification than the immunofluorescence technique.

PMID- 4366921
TI  - Growth of murine cytomegalovirus in a heterologous cell system and its
      enhancement by 5-iodo-2'-deoxyuridine.
AB  - Mouse cytomegalovirus replicated in rabbit kidney cultures, a cell system of
      nonrodent origin. However, the sensitivity of these cultures, and the yields of
      virus therefrom, were lower than those of mouse cultures. Although a cytopathic
      effect developed in rabbit kidney cultures inoculated with sufficient amounts of
      the virus, such cultures were unsatisfactory for plaque assay. This was also true
      when rabbit fibroblast cultures were used, even though the murine cytomegalovirus
      replicated much better in mouse fibroblasts than in mouse kidney cultures, the
      latter of which contained extensive areas of epithelial cells. Viral growth in
      rabbit kidney cells was considerably enhanced when those cells had been initiated
      and grown in the presence of 5-iodo-2'-deoxyuridine; not only were the viral
      titers increased, but also the clarity and distinctness of the inclusion bodies.

PMID- 4366922
TI  - [Mixed tumor of the lacrimal gland and adenoid-cystic carcinoma (author's
      transl)].

PMID- 4366923
TI  - Origin and biological role of molecular asymmetry.

PMID- 4366924
TI  - [Physiologic polymorphism of erythrocyte enzymes].

PMID- 4366925
TI  - Editorial: Tempest in the chickenpot.

PMID- 4366926
TI  - Benign tumors of the hand.

PMID- 4366927
TI  - [Various standards of security and hygiene in the storage and handling of
      cyanides and hydrocyanides. Medical treatment in case of poisoning].

PMID- 4366928
TI  - Molecular mechanisms of temperature compensation in poikilotherms.

PMID- 4366929
TI  - Fetal hamartoma of the kidney--a benign tumour to be distinguished from Wilms'
      tumour.

PMID- 4366930
TI  - The host DNA sequences in different populations of serially passaged SV40.

PMID- 4366931
TI  - Complementation of adeno-associated satellite viral antigens and infectious DNA
      by temperature-sensitive mutants of herpes simplex virus.

PMID- 4366932
TI  - Studies on action mechanisms of a possible false cholinergic transmitter, (2
      hydroxyethyl) methyldiethylammonium.

PMID- 4366933
TI  - A pilgrim's progress in cancer research, 1918 to 1974: autobiographical essay.

PMID- 4366934
TI  - Blood glucose levels and gluconeogenesis in animals bearing transplantable
      tumors.

PMID- 4366936
TI  - Alveolar cell carcinoma-like antigen and antibodies in patients with alveolar
      cell carcinoma and other cancers.

PMID- 4366935
TI  - The presence of the Epstein-Barr viral genome in human lymphoblastoid B-cell
      lines and its absence in a myeloma cell line.

PMID- 4366937
TI  - Mitochondrial protein content and enzyme activity of Reuber hepatoma H-351.

PMID- 4366938
TI  - Inhibition of subcutaneously growing line 1 carcinomas due to metastatic spread.

PMID- 4366939
TI  - Proceedings: Heterogeneity of carcinoembryonic antigen.

PMID- 4366940
TI  - Estrogen excretion in a case of theca-granulosa cell tumor.

PMID- 4366941
TI  - Prolactin binding to rat mammary tumor tissue.

PMID- 4366942
TI  - Anterolateral hypothalamic deafferentation prevents compensatory hypersecretion
      of ACTH following adrenalectomy in the rat.

PMID- 4366943
TI  - Isolation and characterization of a neutral deoxyribonuclease from the testes of
      the crab Cancer pagurus.

PMID- 4366944
TI  - Different expressions of cooperativity in the kinetics of two forms of
      cytoplasmic malic dehydrogenase.

PMID- 4366945
TI  - Determination of the helix and beta form of proteins in aqueous solution by
      circular dichroism.

PMID- 4366947
TI  - DNA-synthesis in the spleen of mice after whole-body X-irradiation and its
      modification by 5-hydroxytryptamine and NADH.

PMID- 4366946
TI  - Fabry's disease: specific inclusions found on electron microscopy of fibroblast
      cultures.

PMID- 4366949
TI  - [Ultrastructure of the human corpus luteum. 2. Evolution during pregnancy].

PMID- 4366948
TI  - Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino
      acids.

PMID- 4366951
TI  - [Segmental aglomerular hypoplasia of the kidney. II. Hypertensive complication
      and results of nephrectomy].

PMID- 4366950
TI  - [Segmental aglomerular hypoplasia of the kidney. I. Associated renal lesions].

PMID- 4366952
TI  - [Introduction to the radiological diagnosis and surgical treatment of lumbalgias.
      Some aspects not to be neglected].

PMID- 4366953
TI  - [Crystalline dystrophy of the cornea. Histological and ultrastructural study].

PMID- 4366954
TI  - 5'-Adenylylation and 5'-uridylation of N-acetyl tyrosine ethyl ester: a general
      synthesis of 5'-nucleotidylated tyrosyl residues.

PMID- 4366955
TI  - Metabolism of glycol-derived lipids in Novikoff hepatomas.

PMID- 4366956
TI  - Nucleotide sequences at the cleavage sites of two restriction endonucleases from
      Hemophilus parainfluenzae.

PMID- 4366957
TI  - The length of repetitive sequences of monkey cell and salmon sperm DNA.

PMID- 4366958
TI  - Decreased basal cyclic adenosine 3',5'-monophosphate levels in Morris hepatoma
      5123 t.c. (h).

PMID- 4366960
TI  - TSH regulation of cAMP-dependent protein kinase activity in the thyroid.

PMID- 4366959
TI  - Stimulation of DNA polymerase activity by the combination of p
      hydroxymercuribenzoate and dithiothreitol.

PMID- 4366961
TI  - Structure-function correlations of formylmethionine transfer RNA.

PMID- 4366962
TI  - A proposed hydrogen transfer function for cytochrome c.
AB  - Outlines of proposed mechanisms for cytochrome c oxidoreduction are presented
      which differ in detail from those previously published. The mechanisms, while
      accommodating the fact that cytochrome c is a net electron acceptor and donor in
      its catalytic cycle, dictate that the enzyme catalyses hydrogen transfer. It is
      shown that the mechanism of cytochrome c reduction fulfills a recent proposal
      that the transition state is an analogue of the structure of ferricytochrome
      c(2). The implications of a hydrogen transfer role of cytochrome c are discussed.

PMID- 4366963
TI  - Preferential inhibition of the growth of virus-transformed cells in culture by
      rifazone-82, a new rifamycin derivative.
AB  - Rifazone-8(2), a new rifamycin derivative, is shown to preferentially inhibit the
      growth of virus-transformed chick cells in culture. Macromolecular synthesis and
      glucose uptake of transformed cells are also appreciably decreased in the
      presence of low concentrations of rifazone-8(2) where the normal cells appear
      unaffected. While rifazone-8(2) is shown to be a selective inhibitor of RNA
      directed DNA polymerase in vitro, its action on the growth of transformed cells
      may involve some other mechanism.

PMID- 4366964
TI  - Structure of cell wall and exocellular mannans from the yeast Hansenula holstii.
      I. Mannans produced in phosphate-containing medium.

PMID- 4366965
TI  - Direct measurement of electric current generation by cytochrome oxidase, H+
      ATPase and bacteriorhodopsin.

PMID- 4366966
TI  - Effects of nucleotides, hormones, ions, and 1,25-dihydroxycholecalciferon on 1,25
      dihydroxycholecalciferol production in isolated chick renal tubules.

PMID- 4366967
TI  - Maintenance of pregnancy in rats on deficient diets.

PMID- 4366968
TI  - Preparation of cell lysate for separation of polyoma DNA from cellular DNA by
      sedimentation velocity.

PMID- 4366969
TI  - Reduced transplantability of syngeneic tumors in rats immunized with allogeneic
      tumors.

PMID- 4366970
TI  - Virus-augmented tumor transplantation antigens: evidence for a Helper antigen
      mechanism.

PMID- 4366971
TI  - Occupational lung cancer among copper smelters.

PMID- 4366972
TI  - Induction of neurogenic tumors in C3HeB-FeJ mice by nitrosourea derivatives:
      observations by light microscopy, tissue culture, and electron microscopy.

PMID- 4366974
TI  - Frequency dependence of dual negative feedback control of secretion of
      sympathetic neurotransmitter in guinea-pig vas deferens.
AB  - The secretion of sympathetic neurotransmitter in guinea-pig vas deferens appears
      to be normally controlled by two different mechanisms, one dependent and one
      independent of prostaglandin E. The efficiency of both control systems, as well
      as of exogenous prostaglandin E(2), is inversely related to nerve stimulation
      frequency.

PMID- 4366973
TI  - Inhibition by diuretics of cyclic 3',5'-AMP-dependent protein kinase from toad
      bladder epithelium.
AB  - 1. A cAMP-dependent protein kinase enzyme has been isolated from toad bladder
      epithelium.2. This enzyme catalyses the phosphorylation of histones; a reaction
      stimulated by 0.1 muM cAMP.3. Activity of this enzyme in the presence of 0.1 muM
      cAMP was significantly inhibited by 100 muM mercuderamide, bumetanide and
      frusemide. A small, though statistically insignificant inhibition was seen with
      the same concentrations of hydrochlorothiazide and ethacrynic acid.4. The half
      maximal inhibition was achieved with mercuderamide, 5 muM, and with frusemide and
      bumetanide 600 muM.

PMID- 4366975
TI  - Basal cell adenoma of intraoral minor salivary gland origin.

PMID- 4366976
TI  - Bronchoscopic diagnosis of cytomegalovirus infection.

PMID- 4366977
TI  - The oncogenicity of Epstein-Barr virus.

PMID- 4366978
TI  - Studies on 1-beta-D-arabinofuranosyl-cytosine (Ara-C) resistant mutants of
      Chinese hamster fibroblasts. II. High resistance to Ara-C as a genetic marker for
      cellular hybridization.

PMID- 4366979
TI  - Cell surface interactions with concanavalin A. Location of bound radiolabeled
      lectin.

PMID- 4366980
TI  - Low resistance junctions between normal and between virus transformed fibroblasts
      in tissue culture.

PMID- 4366981
TI  - A differential chemotactic response of slime mould amoebae to regions of the
      early amphibian embryo.

PMID- 4366982
TI  - Serological studies of normal and leukemic cats in a multiple-case leukemia
      cluster.

PMID- 4366983
TI  - Herpesviruses and cervical cancer.

PMID- 4366984
TI  - Perspectives on the epidemiology of cervical cancer with special reference to the
      herpesvirus hypothesis.

PMID- 4366986
TI  - A nonhuman primate model for the study of the cervical oncogenic potential of
      herpes simplex virus type 2.

PMID- 4366987
TI  - Biochemical approaches to detection of herpes simplex virus type 2 in cervical
      carcinoma.

PMID- 4366985
TI  - Epidemiological studies relating genital herpetic infection to cervical
      carcinoma.

PMID- 4366988
TI  - Discussion of case-control study of Hodgkin's disease.

PMID- 4366989
TI  - Nasopharyngeal carcinoma: recent studies and outlook for a viral etiology.

PMID- 4366990
TI  - Antibodies to herpes group viruses in patients with nasopharyngeal and other head
      and neck cancers.

PMID- 4366991
TI  - Antibody levels to infectious agents other than Epstein-Barr virus in Burkitt's
      lymphoma patients.

PMID- 4366992
TI  - Immunological reactions to tumor-associated antigens in Burkitts lymphoma and
      other lymphomas.

PMID- 4366993
TI  - Epstein-Barr virus DNA in Hodgkin's disease, American Burkitt's lymphoma, and
      other human tumors.

PMID- 4366994
TI  - Animal models: herpesvirus saimiri, a nonhuman primate model for herpesvirus
      associated neoplasia of man.

PMID- 4366995
TI  - Epstein-Barr virus: one or a family of viruses.

PMID- 4366996
TI  - [Pulmonary complications during a course of lymphography with an oily contrast
      media].

PMID- 4366997
TI  - DNA and nucleoprotein changes in liver and tumor nuclei after irradiation.

PMID- 4366998
TI  - Eicosatrienoic acid omega9 in serum lipids of patients with hepatocellular
      carcinoma.

PMID- 4366999
TI  - [The increased activity of unspecific beta-lipoprotein-bound alkaline phosphatase
      in human serum (author's transl)].

PMID- 4367000
TI  - Studies on the dense pre-beta-lipoprotein of human serum.

PMID- 4367001
TI  - 3,4-Methylene hexanedioic acid--a previously unknown compound in human urine.

PMID- 4367003
TI  - [Corticotherapy of bronchial asthma].

PMID- 4367002
TI  - [Cancer of the biliary tract].

PMID- 4367004
TI  - Cell culture of the endocrine pancreas of the mouse in chemically defined media.

PMID- 4367006
TI  - Direct contact between a neuron and soma and myocardial cells; an
      electronmicroscopic finding in the sinus venosus of the turtle heart.

PMID- 4367007
TI  - [Effect of anabolic steroids on skeletal bone differentiation in hypophyseal and
      cerebral (hypothalamic) nanism].

PMID- 4367008
TI  - [Role of serotonin-sensitive structures in the central nervous system in the
      development of compensatory adrenal hypertrophy].

PMID- 4367009
TI  - [Effect of etimizol, ACTH and hydrocortisone on the hypothalamo-hypophyseal
      neurosecretory system of guinea pigs].

PMID- 4367010
TI  - [Functional state of the adrenal cortex of guinea pigs under conditions of
      prolonged and continuous overheating].

PMID- 4367011
TI  - [Criteria for evaluating adrenal cortical reserves by the ACTH test].

PMID- 4367012
TI  - Antiviral compounds. XVI. p-Alkylthiophenylglyoxals and their derivatives.

PMID- 4367013
TI  - [Galactography: indications and diagnostic value (author's transl)].

PMID- 4367014
TI  - [Retrosternal lymphography (author's transl)].

PMID- 4367015
TI  - [The intrapulmonary lymph node. A contribution to the differential diagnosis of a
      single coin lesion. 2 cases (author's transl)].

PMID- 4367016
TI  - [Lobular shadows on lung radiographs (author's transl)].

PMID- 4367018
TI  - [The practical application of discriminant analysis in the diagnosis of
      peripheral bronchial carcinomas (author's transl)].

PMID- 4367017
TI  - [67 gallium in tumour diagnosis (author's transl)].

PMID- 4367020
TI  - [The radiographic appearances of total knee joint endoprosthesis (author's
      transl)].

PMID- 4367019
TI  - [Angiographic findings in two Meckel's diverticula with recurrent bleeding
      (author's transl)].

PMID- 4367021
TI  - Femoral cortical erosions and osteoarthrosis of the knee with chondrocalcinosis.
      An anatomo-radiological study of two cases.

PMID- 4367022
TI  - [Hyperostosis of the radial head--an analogy with hyperostosis of the head of a
      rib (author's transl)].

PMID- 4367023
TI  - [Complex dysplasias of the atlanto-occipital transition zone (author's transl)].

PMID- 4367024
TI  - [Comparative animal experiments concerning the distribution of 99mTc
      pyrophosphate, 99mTc-diphosphonate and 85Sr (author's transl)].

PMID- 4367025
TI  - [Preoperative angiography in traumatic hemobilia].

PMID- 4367026
TI  - [Hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber's disease).
      Angiographic demonstration of pulmonary hepatic and gastric manifestations].

PMID- 4367027
TI  - [Post-traumatic development exostoses between two lumbar spinous processes].

PMID- 4367028
TI  - Clindamycin phosphate in severe infections mainly caused by Bacteroides fragilis:
      clinical and microbiological evaluation.

PMID- 4367029
TI  - The effect of drugs influencing the level of cyclic AMP on angiotensin
      hyperglycaemia in rabbits.

PMID- 4367030
TI  - Seroepidemiology of herpesvirus type Epstein-Barr in blood donors from
      communities around Lyon.

PMID- 4367031
TI  - Occurrence of respiratory illness due to an atypical strain of adenovirus type 11
      during a large outbreak in Spanish military recruits.

PMID- 4367032
TI  - Study of Japanese encephalitis virus in Chiangmia Valley, Thailand. V. Animal
      infections.

PMID- 4367033
TI  - Study of Japanese encephalitis virus in Chiangmia Valley, Thailand. VI. Summary
      and conclusions.

PMID- 4367034
TI  - Use of the delayed brain scan in differentiating calvarial from cerebral lesions.

PMID- 4367035
TI  - Further studies on chemical closure of the Fallopian tubes in the monkey.

PMID- 4367036
TI  - A fluorometric kinetic method for creatine in urine.

PMID- 4367037
TI  - Purification and further characterization of three DNA polymerases of rat Ascites
      hepatoma cells.

PMID- 4367038
TI  - Effect of protein deficiency on the inducibility of the hepatic microsomal drug
      metabolizing enzyme system. 3.

PMID- 4367039
TI  - Inhibition of 2-deoxy-D-glucose transport by theophylline, caffeine and
      papaverine in alveolar macrophages.

PMID- 4367040
TI  - [Comparative evaluation of nuclear medicine and x-ray examination methods in
      nephro-urology. Cooperative study from 16 clinical centers].

PMID- 4367041
TI  - [Comparison of nuclear medicine and radiologic methods in nephro-urology-
      cooperative study from 16 clinical centers].

PMID- 4367042
TI  - [Value of combined radiologic methods. Report on the results of working groups
      and summary].

PMID- 4367043
TI  - [Experimental studies in dogs on the clarification of the detail-recognition in
      angiography and scintigraphy of the kidney].

PMID- 4367044
TI  - [Angiographic and nuclear medicine studies in experimental kidney carcinoma].

PMID- 4367046
TI  - [Value of various examination technics in the diagnosis of parieto-occipital
      glioma].

PMID- 4367045
TI  - [Scintigraphy equals neuroradiology].

PMID- 4367047
TI  - [Comparison of scintigraphy and magnification-angiography with hyperventilation
      in brain tumors].

PMID- 4367048
TI  - [Value of combined radiologic methods in the field of bone diseases].

PMID- 4367049
TI  - [133Xe--99mTc-MAP lung scintigraphy: differential diagnosis of pulmonary
      circulation disorders].

PMID- 4367050
TI  - [Role of combined pulmonary scintigraphy and thoracic radiography in the control
      of patients with inoperable bronchial carcinoma following radiotherapy].

PMID- 4367051
TI  - [Incidence of pulmonary changes following irradiation for breast carcinoma
      (comparison between the x-ray picture and lung scintigraphy)].

PMID- 4367053
TI  - [Indication and achievements of after-care examination in Hodgkin's disease.
      Report on nuclear medicine].

PMID- 4367052
TI  - [Diagnostic value of nuclear medicine liver and bile function tests using 131-I
      BSP in comparison with x-ray diagnostic examination methods].

PMID- 4367054
TI  - [X-ray diagnosis and after-care examinations in Hodgkin's disease].

PMID- 4367055
TI  - [Computer analysis of the results of x-ray studies in the course control of
      patients with Hodgkin's disease].

PMID- 4367056
TI  - [Heart involvement in lymphogranulomatosis].

PMID- 4367057
TI  - [Clinical, clinico-chemical, radiographic and nuclear medicine methods in course
      observations of malignant reticuloses].

PMID- 4367058
TI  - [Pathology of tumors in childhood].

PMID- 4367059
TI  - [Indications for radiotherapy in acute leukemias of the child with special
      reference to clinically not manifested CNS involvement].

PMID- 4367060
TI  - [Diagnostic and therapeutic aspects of neuroblastoma sympathicum].

PMID- 4367061
TI  - [Bone load and influence of bones on dosis distribution in megavolt therapy using
      electrons and photons up to 42 MeV].

PMID- 4367062
TI  - [Effect of ozone in radiotherapy for malignant tumors in the animal experiment].

PMID- 4367063
TI  - [Mammographic indication for excision biopsy in clinically not manifested cases].

PMID- 4367064
TI  - [Combined functional-morphologic studies of the female breast using I.R.
      thermography and the breast-soft-beam exposure technic].

PMID- 4367065
TI  - [Task of the radiotherapist in the treatment of gynecologic neoplasms. Round
      table discussion].

PMID- 4367066
TI  - [Experience report on 40 years of radiotherapy in approximately 1,300
      gynecological cases].

PMID- 4367067
TI  - [Significance of angiography for the thrombolysis of arterial obliterations].

PMID- 4367068
TI  - [Thermography in circulatory disorders of the extremities].

PMID- 4367069
TI  - [Significance of phlebographic and thermographic methods in reflux disorders of
      the leg and pelvic veins].

PMID- 4367070
TI  - [Arterial circulation disorders in diabetes].

PMID- 4367071
TI  - [Angiographic findings after reconstruction of the femoral artery by means of
      venous-interpostition or thrombendarterectomy].

PMID- 4367072
TI  - [Angiographic domonstration of blood circulation disorders of the upper limbs in
      the a.-v. fistula for hemodialysis].

PMID- 4367073
TI  - [Radiation load after intravenous injection of a soluble 192Ir-iridium complex
      combination].

PMID- 4367074
TI  - [Distribution kinetics and biliary excretion of ioglycamate in mini-pig].

PMID- 4367075
TI  - [Importance of the parasternal lymphoscintigram for dosage planning in breast
      carcinoma].

PMID- 4367076
TI  - [Electrophoresis--immunodiffusion--immunoelectrophoresis. Course observations in
      irradiated patients].

PMID- 4367077
TI  - Antibody formation after irradiation and its cellular background.

PMID- 4367078
TI  - [Significance of scintigraphic and radiologic examination methods within the
      scope of lymph node diagnosis or malignant lymphoma].

PMID- 4367079
TI  - [Behavior of PHA-stimulated lymphocytes during a course of after-irradiation in
      patients operated for breast carcinoma].

PMID- 4367080
TI  - [Diverticulosis. Diverticulitis from the radiological viewpoint].

PMID- 4367081
TI  - [Carcinomatous degeneration of inflammatory colonic diseases].

PMID- 4367083
TI  - [Differential diagnosis of Crohn's disease and tuberculosis in ileo-cecal
      region].

PMID- 4367082
TI  - [Psychosomatic aspects of ulcerative colitis].

PMID- 4367084
TI  - [Clinical and x-ray contribution on the "toxic colon"].

PMID- 4367085
TI  - [X-ray diagnosis of coproliths].

PMID- 4367087
TI  - [The deceiving picture of colitis].

PMID- 4367086
TI  - [Radiographic functional diagnosis of the colon for the differential diagnosis of
      colitis].

PMID- 4367088
TI  - [Working program of the IAEC (International Atomic Energy Commission), Dosimetry
      Section in the field of medical use of irradiation].

PMID- 4367089
TI  - [Palacos-stiffening, contribution to the therapy of spinal neoplasms].

PMID- 4367090
TI  - [Comparative thermographic and myelographic studies in lumbosacral disk
      prolapse].

PMID- 4367091
TI  - [Effect of narcotics on coronary arteries].

PMID- 4367092
TI  - [Significance of alkaline phosphatase activity for the x-ray and scintigraphic
      diagnosis of skeletal diseases].

PMID- 4367093
TI  - [Quantitative determination of minerals and phlebographic findings in venous
      blood circulation disorders of the lower limbs].

PMID- 4367094
TI  - [Comparative symptom-analytic and densitometric evaluation of angiographic films
      as illustrated on the example of kidney perfusion].

PMID- 4367095
TI  - [Organizsational incorporation of the physicist into the radiologic institute].

PMID- 4367096
TI  - [Automatic isodosis printer for stationary and non-stationary vertical fields in
      radiotherapy].

PMID- 4367097
TI  - [Testing device for the measurement of important data in construction-technical
      radiation protection for the shielding of electron accelerators through the
      heaviest concrete and 1st measurement results].

PMID- 4367098
TI  - [Function of ITV-systems at the radiographic department of the University
      Hospital in Uppsala].

PMID- 4367099
TI  - [News from the house of C.H.F. Muller, Inc., Hamburg].

PMID- 4367100
TI  - [Comparative evaluation of nuclear medicine and radiographic examination methods
      in nephro-urology using the IATROS system].

PMID- 4367101
TI  - [Organizational forms and procedures of radiotherapeutic departments].

PMID- 4367102
TI  - [Electronic data processing in radiotherapy].

PMID- 4367103
TI  - [Writing automatons or data processing machines].

PMID- 4367104
TI  - Anti-tumor activity in regression fluid.

PMID- 4367105
TI  - Adenocarcinoma of the lung cytologic correlation with histologic types.

PMID- 4367106
TI  - Cellular changes in the glandular epithelium of patients using IUCD--a source of
      cytologic error.

PMID- 4367107
TI  - The lysosome as a mediator of hormone action.

PMID- 4367108
TI  - Endocrine action during insect growth.

PMID- 4367109
TI  - Nerve growth factor and insulin: evidence of similarities in structure, function,
      and mechanism of action.

PMID- 4367110
TI  - Heterogeneity of peptide hormones.

PMID- 4367111
TI  - Microtubule proteins in the nerve growth factor mediated response. Interaction
      between the nerve growth factor and its target cells.

PMID- 4367112
TI  - Insulin secreting pancreatic adenoma demonstrated by selective angiography.

PMID- 4367113
TI  - [Cerebral amines and behavior. Central effects of 6-hydroxydopamine].

PMID- 4367114
TI  - [Pharmacology of GABA derivatives in correlation with the cerebral dopaminergic
      system].

PMID- 4367115
TI  - Preparation of DNA-splitting activities yielding 3'-mononucleotides from the
      sponge Verongia aerophoba.

PMID- 4367116
TI  - Hydrophobic binding sites in bovine serum albumin and erythrocyte ghost proteins.
      Study by spin-labelling, paramagnetic fluorescence quenching and chemical
      modification.

PMID- 4367117
TI  - [Pathogenesis of Schatzki's ring].

PMID- 4367118
TI  - [Monstrous liver angioma unsuccessfully treated by hepatic artery ligation].

PMID- 4367120
TI  - Biological properties of two strains of Simian virus 40 isolated from patients
      with progressive multifocal leukoencephalopathy.
AB  - Biological properties of two strains of simian virus 40 (SV40) from brains of two
      patients with progressive multifocal leukoencephalopathy (PML) have been compared
      to those of a standard laboratory strain of SV40. Infectivity of both SV40-PML
      viruses was resistant to treatment with chloroform, low pH, and 50 C for 120 min.
      African green monkey kidney and BSC-1 cells were the most sensitive for viral
      replication, and cytopathology in these cultures was indistinguishable from that
      caused by SV40. Both viruses formed plaques in these cells. but, in African green
      monkey kidney cells, strain 1 virus produced plaques measuring 2 mm in diameter
      whereas strain 2 virus produced pleomorphic plaques varying from 1 to 10 mm in
      diameter. Hamster cells were not permissive for viral replication, and infection
      resulted only in viral transformation. Inoculation of human fetal glial cells
      resulted in a permissive lytic infection of one cell type and a persistent
      infection with only partial expression of the viral genome in the other. No
      morphological evidence of transformation was evident in the latter cells. Both
      strains of SV40-PML viruses were neutralized by commercial anti-SV40 serum, but
      in reciprocal kinetic neutralization tests differences in K values were noted
      when each was compared to SV40. Both viruses showed oncogenicity for hamsters,
      producing undifferentiated sarcomas when injected subcutaneously and choroid
      plexus papillomas after intracerebral inoculation. All hamster tumor cells
      contained intranuclear immunofluorescent tumor antigen. This was
      indistinguishable from SV40 T antigen in reciprocal staining reactions using
      hamster anti-T antibody induced by the two SV40-PML agents and SV40. These two
      human agents appear therefore to be new variants of simian virus 40.

PMID- 4367119
TI  - Comparison of immunofluorescence and isolation techniques in the diagnosis of
      respiratory viral infections of children.
AB  - The immunoflourescent antibody technique (IFAT) and cell culture isolation
      procedures were compared for their efficiency in the etiological diagnosis of
      viral respiratory illness in children. Before the IFAT was incorporated as a
      routine procedure, antisera used in the test were carefully calibrated to insure
      specificity. A study was then conducted in which 375 nasopharyngeal suctions were
      investigated by both IFAT and isolation for the presence of parainfluenza virus
      types 1, 2, and 3, respiratory syncytial, influenza A, and influenza B viruses.
      Methods already established in our hospital for patient management and specimen
      collection were not altered for the purposes of the study. The IFAT, as
      conventionally practiced in the detection of respiratory virus antigens, requires
      adequate numbers of ciliated epithelial cells. There were 68.5% specimens which
      contained cells suitable for IFAT, whereas 31.5% had either an insufficient
      number or inappropriate types of cells and could be used only for virus
      isolation. Cell-associated immunoglobulins were detected in 16% of those
      specimens with adequate cells. When all specimens were considered regardless of
      their cell population, IFAT was inferior to isolation in diagnostic efficiency.
      However, isolation complemented by IFAT resulted in a statistically significant
      increase in number of positive virus identifications. Under routine working
      conditions in a large pediatric hospital, it was found that IFAT could not
      replace isolation techniques but could, if used in conjunction with isolation,
      provide a significant overall increase in number of positive diagnoses. The time
      that the specimen was taken in relation to first symptoms was found to be an
      important variable with respect to the method most likely to succeed in virus
      identification.

PMID- 4367121
TI  - Hepatocellular localization of fetal antigens during induction of rat liver
      tumors by 3'-methyl-4-dimethylaminoazobenzene.

PMID- 4367122
TI  - Primary neoplasms in dog liver induced by diethylnitrosamine.

PMID- 4367123
TI  - Biosynthesis of globoside and Forssman-related glycosphingolipid in mouse adrenal
      Y-1 tumor cells.

PMID- 4367124
TI  - The effects of di-butyryl cAMP on enzymatic and metabolic changes in explants of
      rat mammary tissue.

PMID- 4367125
TI  - Influence of reserpine-induced depletion of noradrenaline on the negative feed
      back mechanism for transmitter release during nerve stimulation.
AB  - 1. The effects of depletion of endogenous noradrenaline by reserpine-pretreatment
      on [(3)H]-noradrenaline overflow elicited by nerve stimulation were determined in
      the isolated nerve-muscle preparation of the cat's nictitating membrane.2.
      Reserpine pretreatment (0.3 mg/kg, s.c., 4 days prior to the experiment) reduced
      the noradrenaline levels in the smooth muscle of the nictitating membrane to
      about 10% of the control values while granular retention of [(3)H]-noradrenaline
      had recovered to nearly 40% of the controls.3. In the reserpine-pretreated tissue
      the fraction release per shock induced by nerve stimulation was 2.2-fold higher
      than the value obtained in the untreated tissues. This effect was correlated with
      the degree of depletion of the noradrenaline stores rather than with the decrease
      in the response of the effector organ.4. Phenoxybenzamine, 2.9 muM reduced the
      responses to nerve stimulation to the same extent in control and in reserpine
      pretreated tissues. Yet, this concentration of phenoxybenzamine increased by 13
      fold the overflow of the labelled transmitter in the controls and only by 3-fold
      in reserpine-pretreated tissues.5. The decrease in effectiveness of
      phenoxybenzamine in enhancing transmitter overflow after reserpine-pretreatment
      appears to be due to the decrease in the total release of the transmitter.6. The
      results obtained support the view that in reserpine-pretreated tissues decreased
      transmitter output reduces the activation of the presynaptic alpha-adrenoceptors
      which mediate the negative feed-back mechanism that regulates transmitter release
      by nerve stimulation.

PMID- 4367127
TI  - Transformation of chick embryo neuroretinal cells by Rous sarcoma virus in vitro:
      induction of cell proliferation.
AB  - Neuroretinal cells from 7-day-old chick embryos are transformed and induced to
      proliferate after infection with Rous sarcoma virus in vitro. Susceptibility of
      neuroretinal cells to the virus is also dependent on the stage of development
      since infection of cells from 10-day-old embryos is uneffective.

PMID- 4367126
TI  - Presynaptic and postsynaptic effects of the venom of the Australian tiger snake
      at the neuromuscular junction.
AB  - 1. Crude venom (TSV) from the Australian tiger snake (Notechis scutatus scutatus)
      has both presynaptic and postsynaptic effects at the neuromuscular junctions of
      toads.2. TSV (50 mug/ml) rapidly blocked indirectly elicited muscle twitches
      without affecting the compound action potential in the sciatic nerve or twitches
      elicited by direct stimulation.3. Low concentrations of the venom (1-10 mug/ml)
      reduced the amplitude of miniature endplate potentials (m.e.p.ps) and inhibited
      the depolarization of muscle fibres normally caused by carbachol. It was
      concluded that a fraction of the venom binds to acetylcholine receptors.4. The
      frequency of m.e.p.ps was at first increased by TSV at a concentration of 1
      mug/ml. Occasional, high frequency ;bursts' of m.e.p.ps were recorded in some
      preparations. The mean frequency of m.e.p.ps appeared to fall after several hours
      in the venom.5. The quantal content of endplate potentials (e.p.ps) was reduced
      by the venom. With low concentrations (1 mug/ml), an initial increase in quantal
      content was often seen. When the quantal content was markedly depressed there was
      no parallel reduction in the amplitude of nerve terminal spikes recorded
      extracellularly, though a later fall in size and slowing of time course was often
      seen.6. There was evidence that TSV eventually changed the normal Poisson
      characteristics of the spontaneous release of quanta and this may be correlated
      with electronmicroscopic changes in nerve terminals.7. Tiger snake antivenene
      counteracted the postsynaptic, but not the presynaptic effects of TSV when they
      had developed.

PMID- 4367128
TI  - Management of burn syndactyly.

PMID- 4367130
TI  - Degranulation of sensitised rat peritoneal mast cells in response to antigen,
      compound 48-80 and polymyxin B. A scanning electron microscope study.

PMID- 4367131
TI  - Chemotactic responses of human polymorphonuclear leukocytes to cyclic GMP and
      other compounds.

PMID- 4367129
TI  - Studies on a murine form of spontaneous lower motor neuron degeneration--the
      wobbler (wa) mouse.
AB  - The wobbler (wr) mouse has been considered an animal model of spontaneous lower
      motor neuron degeneration which is inherited as an autosomal recessive trait.
      Previously available data are, however, also compatible with genetic factors
      playing a necessary though not exclusive role in the expression of the wobbler
      trait. The present report describes the results of chromosome analyses,
      electromyography and selected histochemical studies on wobbler mice, as well as
      studies exploring the possible participation of infectious agents, transneuronal
      effects, retrograde effects, aging, circulating toxins and immunologic factors in
      the pathogenesis of the wobbler disorder. The data obtained do not implicate any
      of these mechanisms in the pathogenesis of the wobbler trait and also indicate
      that the wobbler mouse is not a clinical variant of the recently described type C
      oncornavirus-induced murine paralytic disease.

PMID- 4367132
TI  - The distribution of 5-bromodeoxyuridine in the DNA of polyoma-transformed mouse
      cells and some apparent effects on transcription.

PMID- 4367133
TI  - Infectious pericarditis in children.

PMID- 4367134
TI  - Muscular hypertrophy in hypothyroid children: the Kocher-Debre-Semelaigne
      syndrome. A review of 23 cases.

PMID- 4367135
TI  - Postural protection against complications in radiculography with dimer X.

PMID- 4367136
TI  - Type-specific tumor patterns in the combined early and late cerebral scintigrams.

PMID- 4367137
TI  - Trophic functions of the neuron. VI. Other trophic systems. Taste bud
      regeneration in organ culture.

PMID- 4367138
TI  - The binding of 1alpha-hydroxycorticosterone to tissue soluble proteins in the
      skate, Raja ocellata.

PMID- 4367139
TI  - Studies on fish liver protein synthesis. I. Isolation and characterization of
      shark liver transfer ribonucleic acid.

PMID- 4367140
TI  - Mutagenicity of hycanthone in Drosophila melanogaster.

PMID- 4367141
TI  - Development of host-mediated mutagenicity tests. I. Differential response of
      yeast cells injected into testes of rats and peritoneum of mice and rats to
      mutagens.

PMID- 4367143
TI  - Assessment of biological age. Methodological study in two finnish populations.

PMID- 4367144
TI  - [Editorial: Progressive encephalopathy and peripheral neuropathy].

PMID- 4367142
TI  - Observations on pathogenic organisms in the airborne state.

PMID- 4367145
TI  - Presynaptic modulation of la fiber synaptic effectiveness without concurrent
      postsynaptic inhibitory conductances.

PMID- 4367146
TI  - Monosynaptic projections from the pontine reticular formation to the 3rd nucleus
      in the cat.

PMID- 4367148
TI  - [Gycogenolysis disorders in the hereditary intolerance to fructose. Study of 2
      cases in children].

PMID- 4367147
TI  - Ultrastructural aspects of the liver in cases of constitutional non haemolytic
      hyperbilirubinemia before and after treatment with barbiturates. Morphological
      aspects of enzymatic induction.

PMID- 4367149
TI  - Canine glomeruli: light and electron microscopic change in biopsy, perfused, and
      in situ autolyzed kidney from normal dogs.

PMID- 4367150
TI  - A review of prostaglandin F2alpha for ovulation control in cows and mares.

PMID- 4367151
TI  - A contribution to the study on embryonal lung cancer (alveogonioma).

PMID- 4367152
TI  - [Bacterial enterotoxins and the diarrhea syndrome].

PMID- 4367153
TI  - [Histamine sensitization induced with Bordetella pertussis and other microbial
      agents].

PMID- 4367154
TI  - [Effect of aminophylline, a phosphodiesterase inhibitor on somatotropin secretion
      after intravenous tolbutamide loading in obese subjects].

PMID- 4367155
TI  - [Value of the analysis of synovial fluid in rheumatology].

PMID- 4367156
TI  - Persistence and expression of the herpes simplex virus type 2 genome in cervical
      tumor cells.

PMID- 4367158
TI  - Transformation of nonhuman primate lymphocytes by Epstein-Barr virus.

PMID- 4367157
TI  - Nasopharyngeal carcinoma: present status of knowledge.

PMID- 4367159
TI  - Uranyl acetate as an excellent fixative for lipoproteins after electrophoresis on
      agarose gel.

PMID- 4367160
TI  - [Comparative study of lipoproteinograms obtained by three different methods
      (author's transl)].

PMID- 4367162
TI  - [Functional state of the insular apparatus of the pancreas in insulinomas in the
      late periods following surgical treatment].

PMID- 4367163
TI  - [Capacity of the peripheral endocrine glands in rats for physiological
      regeneration under the action of tropic hormones a long time after
      hypophysectomy].

PMID- 4367164
TI  - [Editorial: The Australia antigen].

PMID- 4367165
TI  - [In memoriam Professor Hanns Langendorff, Ph. D., D.Sci, M.D. h.c].

PMID- 4367166
TI  - [Comparative lymphographic and sonographic examination of the retroperitoneal
      lymph nodes in malignant lymphomas (author's transl)].

PMID- 4367167
TI  - [The diagnosis of peripheral bronchial carcinomas using discriminant analysis
      (author's transl)].

PMID- 4367168
TI  - [Trans-lumbar abdominal and thoracic catheter angiography (author's transl)].

PMID- 4367169
TI  - [Abnormal vascular patterns in the hand. A contribution to its differential
      diagnosis (author's transl)].

PMID- 4367170
TI  - [Osseous haemophilic pseudo-tumours (author's transl)].

PMID- 4367172
TI  - Antineoplastic substances from the sea: a review.

PMID- 4367174
TI  - Interrelation of afferent impluses from different bellies of the temporal muscle
      of the cat.

PMID- 4367173
TI  - Formation of high-energy phosphate bonds effected by electron-deficient sulfides.

PMID- 4367171
TI  - Newer beta-lactam antibiotics.

PMID- 4367175
TI  - Pathways for glucose metabolism in the rat gingiva. I. Patterns of enzymes of
      glucose metabolism.

PMID- 4367176
TI  - Meningeal and glial tumors in combination.

PMID- 4367177
TI  - [S.N.V. and insulin secretion. 3. Restorative effect of aminophylline a
      phosphodiesterase inhibitor, on catecholamine inhibition of insulin secretion].

PMID- 4367178
TI  - Cross-reacting tumor-associated antigen(s) of adenovirus type 9-induced
      fibroadenomas and a chemically induced mammary carcinoma in rats.

PMID- 4367179
TI  - Enhanced Na+-K+-activated adenosine triphosphatase activity in transformed
      fibroblasts.

PMID- 4367180
TI  - Radioimmunoassay for mouse mammary tumor virus-associated antigen.

PMID- 4367182
TI  - Klinefelter syndrome and cancer. A family study.

PMID- 4367183
TI  - [Esophageal duplication and cancer of the esophagus].

PMID- 4367181
TI  - The immunologic modulation of infectious disease pathogenesis. Friedenwald
      Lecture, 1973.

PMID- 4367184
TI  - [Slow developing (7 and-a-half years) voluminous stomach cancer with negative
      directed biopsy].

PMID- 4367185
TI  - [Isolated schwannoma of the rectum].

PMID- 4367186
TI  - Association of Wolff-Parkinson-White syndrome with congenital abnormalities of
      hands and feet.

PMID- 4367187
TI  - [Results of serial-scintigraphy in cerebrovascular attacks].

PMID- 4367188
TI  - [Value of combined radiologic methods. Neuroradiology. Report on the results of
      working groups and summary].

PMID- 4367189
TI  - [Molecular mechanisms in the repair of radiation damage to lymphocytes].

PMID- 4367190
TI  - [Servicing and care for video-instruments].

PMID- 4367191
TI  - [Influence of new x-ray-technical developments on the organization and planning
      of x-ray departments].

PMID- 4367192
TI  - Suggestive evidence for an oncorna-virus-specific DNA polymerase from C-type
      particles of bovine leukosis.

PMID- 4367193
TI  - A sporadic case of apparent Crouzon's syndrome with extracraniofacial
      manifestations.

PMID- 4367194
TI  - Electroneurography in intermittent claudication due to obliterative
      arteriosclerosis.

PMID- 4367196
TI  - [Vascular anomalies in limb deformities].

PMID- 4367195
TI  - [Angiographic and isotope-nephrologic evaluation of renal artery stenosis].

PMID- 4367197
TI  - Association of PPi-phosphohydrolytic activity with fractions of alkaline
      orthophosphatase (EC 3.1.3.1) from human placenta.

PMID- 4367198
TI  - Influence of sodium and cyclic AMP on the passive permeability of the mucosal
      membrane in the rat intestine.

PMID- 4367199
TI  - The lysosomal enzymes in the regression of the mesonephron. Histochemical
      observations on chick embryo development.

PMID- 4367200
TI  - Isolation of infectious bovine rhinotracheitis virus from feces of a feeder
      steer.

PMID- 4367201
TI  - Epipolythiopiperazinedione antibiotics from Penicillium turbatum.

PMID- 4367202
TI  - [Fasting hypoglycemias and postprandial hypoglycemias: a distinction useful for
      functional exploration].

PMID- 4367204
TI  - [Synteny of enolase (PPH) and the markers assigned to chromosome 1 (study of man
      hamster and man-mouse cellular hybrids)].

PMID- 4367203
TI  - [The insulin-glucose ratio: its value in diagnosis of hypoglycemic islet cell
      tumors].

PMID- 4367205
TI  - [Papulous stomatitis in bovines].

PMID- 4367206
TI  - [Electrokinetic behavoir of Ehrlich ascites tumor cells following infection with
      oncolytic influenza viruses].

PMID- 4367207
TI  - [Myxovirus hepatitis: a model].

PMID- 4367208
TI  - Adenoid cystic carcinoma in the head and neck (cylindroma).

PMID- 4367209
TI  - The resident's page: pathologic quiz case 2.

PMID- 4367210
TI  - Three dimensional structure of adenyl kinase.

PMID- 4367212
TI  - Topological comparison of adenyl kinase with other proteins.

PMID- 4367211
TI  - Comparison of predicted and experimentally determined secondary structure of
      adenyl kinase.

PMID- 4367213
TI  - Food vacuole membrane in nutrient uptake by Tetrahymena.

PMID- 4367214
TI  - The reaction of xanthine oxidase with molecular oxygen.

PMID- 4367215
TI  - The mechanism of action of xanthine oxidase.

PMID- 4367217
TI  - Effects of temperature on conformation, hydroxylation, and secretion of chick
      tendon procollagen.

PMID- 4367216
TI  - Effect of sulfate on the activity and the kinetics of dexoyribonucleic acid
      degradation by porcine spleen deoxyribonuclease.

PMID- 4367218
TI  - Heme-spin label studies of hemoglobin. I. Preparation and properties of heme-spin
      labeled ferrihemoglobin.

PMID- 4367219
TI  - The mechanism of action of ethanolamine ammonia-lyase, a B-12-dependent enzyme.
      The participation of paramagnetic species in the catalytic deamination of 2
      aminopropanol.

PMID- 4367220
TI  - Interactions of saccharides with concanavalin A. Relation between calcium ions
      and the binding of saccharides to concanavalin A.

PMID- 4367221
TI  - Selective binding of human interferon to albumin immoblized on agarose.

PMID- 4367222
TI  - The recovery of anaerobic bacteria from swabs.
AB  - When a standard sample of simulated exudate containing known numbers of anaerobic
      bacteria was taken up on a swab and plated on solid medium, the number of
      colonies subsequently cultured represented a very small proportion of the
      original sample. Evidence is produced that the apparent loss is not primarily
      attributable to inactivation on the swab but rather to retention of organisms on
      the swab. This was demonstrable with Clostridium welchii and with Bacteroides
      species that have hitherto been regarded as relatively oxygen-sensitive.When
      stock strains of Bacteroides species were held for some hours on swabs, some
      progressive loss of viability was demonstrable. A measure of protection was
      afforded when these organisms were held aerobically on blood agar medium, but a
      very exacting anaerobe and some wild strains of faecal anaerobes showed gradual
      inactivation under these conditions.These findings may have important
      implications in relation to currently employed bacteriological sampling
      procedures with swabs in clinical practice.

PMID- 4367223
TI  - A study of foot-and-mouth disease virus strains by complement fixation. I. A
      model for the fixation of complement by antigen-antibody mixtures.
AB  - An examination was made of the relations between antigen, antibody and fixation
      of complement with foot-and-mouth disease virus (FMDV). It was found that
      complement fixation in this system follows the same principles as models
      developed in other antigen/antibody systems. The assumption that there is a
      relation of direct proportionality between the amount of complement fixed and the
      amount of antiserum reacting with constant antigen was found to be incorrect. An
      alternative method was proposed for the quantitative differentiation of FMDV
      strains by comparing the titres of an antiserum when reacting with optimum
      amounts of homologous or heterologous antigens.

PMID- 4367224
TI  - A study of foot-and-mouth disease virus strains by complement fixation. II. A
      comparison of tube and microplate tests for the differentiation of strains.
AB  - Several foot-and-mouth disease virus strains were examined by complement-fixation
      tests in microplates and in tubes. It was established that the two systems are
      comparable, although greater reproducibility is obtained with tube tests. While
      microplate tests are a satisfactory method for the differentiation of strains,
      tube tests provide a more precise method for the identification of small
      antigenic differences.

PMID- 4367227
TI  - Diagnosis of idiopathic hypertrophic subaortic stenosis by right ventricular
      septal biopsy.

PMID- 4367225
TI  - Viruses associated with acute respiratory infections 1961-71.
AB  - Influenza-like illness, cold and sore throat was the diagnosis given in over 80%
      of 5177 acute respiratory illnesses in patients swabbed over a 10-year-period. A
      pathogenic organism was isolated twice as frequently from patients with a sore
      throat or an influenza-like illness as from those diagnosed as suffering from
      croup or laryngitis and bronchitis. A laboratory diagnosis was commoner in school
      children than in older or younger persons.Most of the organisms isolated were
      found in association with all types of acute respiratory illness but, with
      increasing age of the patient, one particular agent or group of agents was more
      likely to be of aetiological significance.

PMID- 4367226
TI  - Antibodies against adeno-, cytomegalo and rubella viruses in Australia-antigen
      negative sera from patients with infectious hepatitis.
AB  - Antibodies neutralizing adenovirus type 5 were found in all of 50 pairs (100%) of
      sera from patients with acute icteric infectious hepatitis. The incidence in sera
      from the general population was 57%. No differences in mean titre or in
      proportion of positive sera were found in the same sera tested for complement
      fixing antibodies to cytomegalovirus and for antibodies to rubella virus
      haemagglutinin. The results can be interpreted as supporting the involvement,
      either direct or indirect, of adenovirus in the aetiology of infectious
      hepatitis; but could also be due to a non-specific anamnestic enhancement of the
      production of antibody to adenovirus, or to coincidental infection with
      adenovirus and the agent of infectious hepatitis.

PMID- 4367228
TI  - The Golgi complex. II. The effects of aminonucleoside on ultrastructure and
      glycoprotein biosynthesis.

PMID- 4367229
TI  - The Brenner tumor and the Walthard cell nest. An electron microscopic study.

PMID- 4367230
TI  - Ultrastructure of the parafollicular (C) cells and the parathyroid cell in
      growing dogs on a high calcium diet.

PMID- 4367231
TI  - Pharmacologic effects of nicotinic acid on human purine metabolism.

PMID- 4367232
TI  - Evaluation of a new mucolytic drug.

PMID- 4367234
TI  - Spontaneous eyelid behavior in the sleeping cat.

PMID- 4367233
TI  - [1st experiences in the treatment of ovarian tumors with Peptichemio].

PMID- 4367235
TI  - Effects of glutamate on spontaneous electrical activity in the embryonic chick
      cerebrum.

PMID- 4367236
TI  - Rigidity and primary motoneuron damage in tetanus.

PMID- 4367237
TI  - The uptake process for gamma-aminobutyric acid in cultures of developing chick
      cerebrum.

PMID- 4367238
TI  - Superinfection with adenovirus of Burkitt's lymphoma cell lines.

PMID- 4367239
TI  - Isolation and characterization of a cell line from the cocultivation of Lucke
      renal tumor cells and nontransformed feeder cells.

PMID- 4367240
TI  - Effects of partial hepatectomy on carcinogenicity, metabolism, and binding to DNA
      of ethyl carbamate.

PMID- 4367241
TI  - Cell culture from a rat brain tumor induced by intracerebral inoculation with
      murine sarcoma virus.

PMID- 4367242
TI  - Effect of cyclopropenoid compounds on the carcinogenic activity of
      diethylnitrosamine and aflatoxin B1 in rats.

PMID- 4367243
TI  - Neuraminidase and cell viability: failure to detect cytotoxic effects with dye
      exclusion techniques.

PMID- 4367245
TI  - Suppression of chemically induced pulmonary tumors by treatment of strain A mice
      with murine sarcoma virus.

PMID- 4367244
TI  - In vivo inhibition of murine leukemia and sarcoma viruses by the heteropolyanion
      5-tungsto-2-antimoniate.

PMID- 4367246
TI  - The murine male antigen. 3. Variable expression of H-Y by murine tumors.

PMID- 4367247
TI  - Ultrastructural studies of cell-virus interaction in reptilian cell lines. II.
      Distribution, incidence, and factors enhancing the production of
      intramitochondrial virions.

PMID- 4367248
TI  - Destruction of syngeneic tumors by tuberculin-stimulated peritoneal exudate cells
      from guinea pigs immunized to Mycobacterium bovis (strain BCG).

PMID- 4367250
TI  - Several changes associated with the acquisition of a single chromosome in rat
      glial tumor cells.

PMID- 4367249
TI  - Induction of adenofibrosis and hepatomas of the liver in BALB-cJ mice by
      polychlorinated biphenyls (Aroclor 1254).

PMID- 4367251
TI  - Treatment of metastatic Wilm's tumor.

PMID- 4367252
TI  - Editorial: The "oat-cell" tumors: a medical and biological challenge.

PMID- 4367253
TI  - Drug levels in the target tissue and effect.

PMID- 4367254
TI  - Blood level measurements and antimicrobial agents.

PMID- 4367255
TI  - The supine subcostal modification of the thoraco-abdominal incision.

PMID- 4367256
TI  - Peritubular membrane transport of PAH into proximal cells in Necturus kidney
      slices.

PMID- 4367257
TI  - Zinc deficiency and decreased pancreatic secretory response.

PMID- 4367258
TI  - Comparison of the effects of cholera enterotoxin and ACTH on adrenal cells in
      tissue culture.

PMID- 4367260
TI  - Effect of pH on epinephrine-induced lipolysis in isolated fat cells.

PMID- 4367259
TI  - Pulmonary adema and hemorrhage as a consequence of systemic vasoconstriction.

PMID- 4367261
TI  - Influence of sodium, potassium, and pituitary hormones on iso-renin in rat
      adrenal glands.

PMID- 4367262
TI  - Computer-assisted analysis of chromosomal abnormalities: detection of a deletion
      in aniridia-Wilms' tumor syndrome.
AB  - A chromosome translocation, t(8p + ; 11q -), in a patient with aniridia and
      Wilms' tumor, appeared balanced by standard techniques, including trypsin
      banding. Computer analysis of optical microscope scanning profiles of chromosome
      pairs 8 and 11 revealed an interstitial deletion of the short arm of 8. Computer
      analysis coupled to the new banding techniques provides greater resolution for
      the detection of subtle chromosomal variations not recognized by banding methods
      alone.

PMID- 4367263
TI  - Toxic polyneuropathy produced by methyl N-butyl ketone.
AB  - A polyneuropathy affecting a large number of workers was recently observed at a
      plant producing plastic-coated and color-printed fabrics. Epidemiological data
      suggested strongly that methyl N-butyl ketone (MBK) was responsible for the
      outbreak. This hypothesis is now supported by the development of a peripheral
      neuropathy in chickens, rats, and cats exposed to MBK at atmospheric
      concentrations of 200 to 600 parts per million, 24 hours per day, 7 days per
      week. Although the animals were exposed continuously and the affected workers
      were exposed intermittently, the averages of the total number of hours of
      exposure for development of the peripheral neutropathy in the animals and workers
      were remarkably close.

PMID- 4367265
TI  - Animal model of human disease. Burkitt's lymphoma, malignant lymphoma and
      lymphocytic leukemia.

PMID- 4367266
TI  - [Letter: Antithyroid therapy].

PMID- 4367264
TI  - Cancer of the pancreas induced in the Syrian golden hamster.
AB  - A high incidence of pancreatic neoplasms was induced in Syrian golden hamsters
      following subcutaneous applications of diisopropanolnitrosamine (DIPN) once
      weekly for life. The tumor latency was as short as 15 weeks. In clinical and
      morphologic aspects the induced pancreatic tumors closely resembled those of
      humans.

PMID- 4367267
TI  - Altering lipid patterns in adult males.

PMID- 4367268
TI  - The renin-angiotensin system (second of two parts).

PMID- 4367269
TI  - Reduced calcium absorption after nephrectomy in uremic patients.

PMID- 4367270
TI  - Case records of the Massachusetts General Hospital. Weekly clinicopathological
      exercises. Case 34-1974.

PMID- 4367271
TI  - Cellular pathology and uterine cancer. Ward Burdick Award address.

PMID- 4367272
TI  - Autoimmunity and neoplasia. The possible role of C-type viruses.

PMID- 4367273
TI  - Effects of actinomycin D on RNA metabolism in the growing hair follicles of the
      mouse.

PMID- 4367276
TI  - Macrodactyly and localized hypertrophic neuropathy.

PMID- 4367275
TI  - Ocular myasthenia gravis mimicking progressive external ophthalmoplegia. Rare
      case of myasthenia associated with peripheral neuropathy and spastic paraparesis.

PMID- 4367274
TI  - Carcinoma of the gallbladder and extrahepatic biliary tree.

PMID- 4367277
TI  - The innervation of muscle spindles in a case of hypertrophic polyneuropathy.

PMID- 4367278
TI  - The fate of kidney transplants from donors with minor renal abnormalities.

PMID- 4367279
TI  - Trace elements in noraml and malignant human breast tissue.

PMID- 4367280
TI  - Oestrogen assays in gynaecology.

PMID- 4367281
TI  - Letter: Effect of exogenous oestrogens on minor psychiatric symptoms in
      postmenopausal women.

PMID- 4367282
TI  - Prevention of food poisoning in hospital patients.

PMID- 4367283
TI  - Enhancement of 7,12-dimethylbenzanthracene skin carcinogenesis by adenosine 3',5'
      cyclic monophosphate.

PMID- 4367284
TI  - The preparation of microsomal fractions of rodent respiratory tract and their
      characterization.

PMID- 4367285
TI  - A comparative study of rat liver, muscle, and hepatoma 3924A phosphofructokinase
      isozymes.

PMID- 4367286
TI  - Endogenous type C particles from rat embryo cells treated with 5
      bromodeoxyuridine.

PMID- 4367287
TI  - Synthesis, toxicities, and carcinogenicities of carcinogenic bifunctional
      aminoazo dyes.

PMID- 4367288
TI  - Isozyme patterns of pyruvate kinase in various primary liver tumors induced
      during the process of hepatocarcinogenesis.

PMID- 4367289
TI  - Substrate requirements and kinetic analysis of the cortisol effects on uridine
      uptake and incorporation by mouse lymphoma P1798 cells in vitro.

PMID- 4367290
TI  - Rabbit antibodies to nucleoli of Novikoff hepatoma and normal liver of the rat.

PMID- 4367291
TI  - Polyamine depletion of tumor tissue and subsequent elevation of spermidine in the
      sera of rats with 3924A hepatomas after 5-fluorouracil administration.

PMID- 4367292
TI  - Stromal nephromas and renal cell tumors in suckling and weaned rats.

PMID- 4367293
TI  - Transfer RNA methylase activity in benign human ovarian neoplasms.

PMID- 4367294
TI  - [Acetylcholinesterase activity of Pacini's corpuscles].

PMID- 4367296
TI  - [Circadian variations of plasma renin activity in normal women].

PMID- 4367295
TI  - Overview on pathogenesis of cardiac hypertrophy.

PMID- 4367297
TI  - Massive hemothorax: two unusual cases.

PMID- 4367299
TI  - Travelers' warning: dipyrone in over-the-counter drugs.

PMID- 4367298
TI  - Bilateral symmetrical metastases to the clavicular heads from bronchogenic
      carcinoma simulating primary hyperparathyroidism.

PMID- 4367300
TI  - Proceedings: Electron spin resonance study of the role of calcium in the
      fibrinogen fibrin reaction.

PMID- 4367302
TI  - A temperature-sensitive mutant of herpes simplex virus type 1 defective in the
      synthesis of the major capsid polypeptide.

PMID- 4367301
TI  - The role of transferrin in iron transport.

PMID- 4367303
TI  - Inhibition of foot-and-mouth disease virus replicase by frog virus 3 particles.

PMID- 4367304
TI  - The induction of deoxythymidine kinase by bacteriophage T4.

PMID- 4367305
TI  - Electron microscopic observations on the entry of influenza virus into
      susceptible cells.

PMID- 4367306
TI  - Transformation of rat embryo cells by temperature-sensitive mutants of herpes
      simplex virus.

PMID- 4367307
TI  - Inactivation of some bacterial and animal viruses by exposure to liquid-air
      interfaces.

PMID- 4367308
TI  - The IgG receptor induced by herpes simplex virus: studies using radioiodinated
      IgG.

PMID- 4367310
TI  - A clinical test useful for predicting the development of acute hypertension in
      pregnancy.

PMID- 4367309
TI  - Absence of a requirement for host polypeptides in the herpes virus thymidine
      kinase.

PMID- 4367311
TI  - Treatment of gestational trophoblastic disease.

PMID- 4367312
TI  - Relative importance of viral and neoantigens in cytotoxic reaction against murine
      leukaemia cells.

PMID- 4367313
TI  - Simple siliceous pneumoconiosis in Negev Bedouins.

PMID- 4367315
TI  - The inhibition of mouse bone collagenase by lysozyme.

PMID- 4367314
TI  - The lipids of matrix vesicles from bovine fetal epiphyseal cartilage.

PMID- 4367316
TI  - Vibrational spectra of some phosphate salts amorphous to X-ray diffraction.

PMID- 4367317
TI  - The effect of galactose on bone metabolism.

PMID- 4367318
TI  - Vitamin A deficiency stimulated phosphatase activity in epiphyseal chick
      cartilage.

PMID- 4367320
TI  - Antibody to leukemia virus: widespread occurrence in inbred mice.
AB  - Mice from a wide variety of inbred strains produce immunoglobulin G antibody
      against murine leukemia virus. This is contrary to the common view that the mouse
      is immunologically tolerant to its endogenous leukemia virus.

PMID- 4367319
TI  - Human serum albumin phenotype activation in mouse hepatoma--human leukocyte cell
      hybrids.
AB  - Murine hepatoma cells that secreted mouse serum albumin were fused with human
      leukocytes that did not produce albumin. The resulting hybrids secreted both
      mouse and human serum albumin, as demonstrated by immuno-electrophoretic
      techniques. The activation of the human genome suggests that mapping genes
      governing specialized functions in somatic cell hybrids may be accomplished by
      using adifferentiated human cells as a parental line.

PMID- 4367321
TI  - Cytochemical, ultrastructural, and autoradiographic study of the intranuclear
      crystals in the midgut cells of Gyrinus marinus Gyll.

PMID- 4367322
TI  - Affinity chromatography. New approaches for the preparation of spacer containing
      derivatives and for specific isolation of peptides.

PMID- 4367323
TI  - Cooperative effects of AMP, ATP and fructose 1,6-P2 on the specific elution of
      fructose 1,6-diphosphatase from cellulose phosphate.

PMID- 4367324
TI  - The biosynthesis of riboflavin: affinity chromatography purification of GTP-ring
      opening enzyme.

PMID- 4367325
TI  - Immobilized polynucleotides and nucleic acids.

PMID- 4367326
TI  - Immobilized cofactors and multi-step enzyme-systems.

PMID- 4367327
TI  - Preparation, characterization and applications of enzymes immobilized on
      inorganic supports.

PMID- 4367328
TI  - The optimization of porous materials for immobilized enzyme (IME) systems.

PMID- 4367330
TI  - Chain refolding and subunit interactions in enzyme molecules covalently bound to
      a solid matrix.

PMID- 4367329
TI  - The preparation of microenvironments for bound enzymes by solid phase peptide
      synthesis.

PMID- 4367331
TI  - Use of immobilized enzymes for synthetic purposes.

PMID- 4367332
TI  - Studies on the site of origin of the androgen binding protein present in
      epididymal cytosol from mature intact rabbits.

PMID- 4367333
TI  - Androgen binding protein (ABP) in rabbit testis and epididymis.

PMID- 4367334
TI  - [Clinical relevance of photosensitivity in psychiatric EEG diagnosis].

PMID- 4367335
TI  - [Ultrastructure and secretion studied using tritiated leucine in human
      somatotropin secreting adenoma in tissue culture (author's transl)].

PMID- 4367336
TI  - [Pituitary cytology in a case of paraneoplastic hypercorticism (author's
      transl)].

PMID- 4367337
TI  - [Pituitary adenomas in Cushing disease. A study of 21 cases (author's transl)].

PMID- 4367339
TI  - In vitro cellular immunity to Epstein-Barr virus in normal human subjects.

PMID- 4367338
TI  - Disappearance of a major cell-type specific surface glycoprotein antigen (SF)
      after transformation of fibroblasts by Rous sarcoma virus.

PMID- 4367340
TI  - Attempts to detect virus-secific DNA in human tumors. I. Nucleic acid
      hybridizations with complementary RNA of human wart virus.

PMID- 4367341
TI  - Attempts to detect virus-specific DNA in human tumors. II. Nucleic acid
      hybridizations with complementary RNA of human herpes group viruses.

PMID- 4367342
TI  - An analysis of variables affecting the measurement of tumor immunity in vitro
      with 125I-iododeoxyuridine-labelled target cells. Studies of immunity to primary
      Moloney sarcomas.

PMID- 4367343
TI  - Cell-mediated and humoral immunity studies of murine and hamster sarcoma virus
      induced producer and non-producer tumors in syngeneic animals.

PMID- 4367344
TI  - Proceedings: Influence of large doses of rifampicin on mammalian embryonic
      development.

PMID- 4367346
TI  - Proceedings: Calcium-dependent changes of adenylate cyclase activity by
      adenosine.

PMID- 4367347
TI  - Proceedings: Effects of cyclic nucleotide monophosphates (cAMP, dbcAMP, cGMP,
      cIMP) on transepithelial netfluxes in proximal convolutions of rat kidneys.

PMID- 4367345
TI  - Proceedings: The effect of PGE1, PGE2 and PGF2alpha on parasympathetic
      transmission.

PMID- 4367349
TI  - Proceedings: Angiotensin receptors in the adrenal cortex.

PMID- 4367348
TI  - Proceedings: Iso-renin in adrenal glands of rats: a possible factor in steroid
      production.

PMID- 4367350
TI  - Proceedings: The specificity of membranes of chromaffin granules: a biochemical
      and immunohistological study.

PMID- 4367351
TI  - Proceedings: The action of tetanus toxin on the electrical activity of the
      rabbit's brain.

PMID- 4367353
TI  - Proceedings: Influence of hydroxyphenyl-orciprenalin (HO) on the cAMP level and
      the motility of the rat uterus in vitro.

PMID- 4367354
TI  - Proceedings: Cardiac effects of dibutyryl-C-AMP in several mammalian species.

PMID- 4367352
TI  - Proceedings: (14C)-labelling and fractionation of lipids in bovine glomerular
      basement membrane.

PMID- 4367355
TI  - Proceedings: Investigation of the antilipolytic action of clomiphene.

PMID- 4367356
TI  - Proceedings: Effect of nicotine and nicotine monomethiodide on vascular
      adrenergic neuroeffector transmission.

PMID- 4367357
TI  - Proceedings: Studies on the inhibitory effect of pepstatin on the renin-
      angiotensinogen reaction.

PMID- 4367358
TI  - Proceedings: Demonstration of the in vivo action of pepstatin: effects on plasma
      angiotensin II concentration (PAC).

PMID- 4367359
TI  - Proceedings: Effects of antiphlogistic drugs on the adenyl cyclase system of
      fibroblasts.

PMID- 4367360
TI  - Proceedings: Synthesis of cyclic AMP and cyclic AMP-mediated protein
      phosphorylation in rat erythrocytes.

PMID- 4367361
TI  - Proceedings: Effect of cholinergic mechanisms on rat gastric mucosal cAMP.

PMID- 4367363
TI  - Proceedings: Effect of tropolone on vascular sympathetic neuroeffector
      transmission.

PMID- 4367362
TI  - Proceedings: The ciliary ganglion of the cat: pharmacological aspects.

PMID- 4367364
TI  - Proceedings: The effect of norepinephrine on cyclic nucleotide concentrations in
      rat ductus deferens.

PMID- 4367365
TI  - Proceedings: Adenosine 3',5'-monophosphate in cerebral cortical slices from
      guinea pig and rat: effect of benzodiazepines.

PMID- 4367367
TI  - [Immunology and immunotherapy of cerebral tumors. Current status].

PMID- 4367366
TI  - Proceedings: Effect of the alpha-receptor blocking agent phentolamine on cAMP
      levels and release of glycerol in isolated rat fat cells.

PMID- 4367368
TI  - The evaluation of the experience of various European countries in cancer control.

PMID- 4367369
TI  - [Adrenal hypertrophy following lesions of pontile catecholaminergic neurons in
      the rat].

PMID- 4367370
TI  - [Action of calcium, EGTA and EDTA on adenyl cyclase activity in subcellular
      preparations of corticoadrenal glands].

PMID- 4367371
TI  - A fine structural study of human oral epithelium separated from the lamina
      propria by enzymatic action.

PMID- 4367372
TI  - A cytoplasmic inclusion in mouse trigeminal neurons (1).

PMID- 4367373
TI  - Primary breast cancer: some considerations concerning its management.

PMID- 4367374
TI  - Brain lipid changes following hypoxia.

PMID- 4367376
TI  - Specificity of rabbit IgM and IgG antibody in intratypic differentiation of
      poliovirus type I strains.

PMID- 4367375
TI  - Effect of histone on oncogenic properties of Moloney's murine sarcoma virus.

PMID- 4367377
TI  - Herpesvirus strigis: a new avian herpesvirus. I. Biological properties.

PMID- 4367378
TI  - Composition of poliovirus fibrils.

PMID- 4367379
TI  - Nelson Bay virus. A novel reovirus.

PMID- 4367380
TI  - Precipitating antibodies against maedi-visna virus in experimentally infected
      sheep.

PMID- 4367382
TI  - In vivo behaviour of a temperature-sensitive (ts) mutant of herpesvirus hominis
      type 2.

PMID- 4367381
TI  - Biological and biophysical characterization of SV40 cytoplasmic T-antigen
      inducing mutants of PARA-adenovirus 7.

PMID- 4367384
TI  - Infections with herpesviruses in a closed infants' community.

PMID- 4367385
TI  - Strain specific cell-mediated response to polyoma-transformed fibroblasts in
      mice.

PMID- 4367386
TI  - Rational surgery for tumors of the ovary in children.

PMID- 4367387
TI  - [Syndrome of osteomalacia in relation to the biological value of hatching eggs].

PMID- 4367383
TI  - Further studies on the development of Yaba poxvirus in cell culture.

PMID- 4367388
TI  - [Serum lipoproteins in geese].

PMID- 4367389
TI  - Hyperlipoproteinemia--relation to platelet lipids, platelet function and tendency
      to thrombosis.

PMID- 4367390
TI  - Applications of phospholipase C in the study of membranes.

PMID- 4367391
TI  - [Contribution of neuroradiology to the diagnosis of glomus jugulare tumors].

PMID- 4367392
TI  - [Differentiation and ultrastructure of the distal skeleton of the pectoral fin of
      the native trout (Salmo trutta fario L.). I. Differentiation and ultrastructure
      of the actinotrichia].

PMID- 4367393
TI  - Postsynaptic effects evoked from brain stem reticular formation in lumbar cord
      and their temporal correlations with a presynaptic mechanism.

PMID- 4367394
TI  - [Aschoff's nodule: ultrastructural study].

PMID- 4367395
TI  - Inhibition studies of dehydrogenases by structural analogues of NAD.

PMID- 4367396
TI  - [Study of intrapulmonary mineral deposits by electron microscopy, electron probe
      microanalysis and electron microdiffraction].

PMID- 4367397
TI  - Treatment of respiratory distress in the newborn infant.

PMID- 4367398
TI  - [Hyaline membrane disease. Immunofluorescent study. The role of complement].

PMID- 4367400
TI  - Cytochemical localization of cyclic nucleotide phosphodiesterase activity at
      developing synapses.

PMID- 4367399
TI  - Tonotopic organization: review and analysis.

PMID- 4367401
TI  - Signal transmission through degenerating synapses in the lateral geniculate body
      of the cat.

PMID- 4367402
TI  - Phosphatases in the substantia gelatinosa and motoneurones: a comparative
      histochemical study.

PMID- 4367403
TI  - [Influence of the level and quality of dietary proteins on variations of the
      enzyme activity: pyruvate kinase(PK), glucose-6-P-dehydrogenase (G6PDH), malic
      enzyme(ME), glutamic pyruvate transaminase(GPT), glucose-6-phosphatase(G6Pase)
      and phosphoenol pyruvate carboxykinase(PEPCK) in the rat].

PMID- 4367404
TI  - [Immunopotentiation by thiols and disulfides].

PMID- 4367405
TI  - Binding of 3H-labelled cobra neurotoxin to cholinergic receptors in fast and slow
      mammalian muscles.

PMID- 4367406
TI  - Cholinergic suppression of tardive dyskinesia.

PMID- 4367407
TI  - Effects of methylphenidate on hyperactive children's sleep.

PMID- 4367408
TI  - Sensory conduction of the sural nerve in polyneuropathy.
AB  - Using surface electrodes, sensory nerve action potentials (SAP) have been
      recorded in the proximal segment (mid-calf to lateral malleolus) and the distal
      segment (lateral malleolus to toe 5) of the sural nerve and in the median nerve
      in 79 control subjects. The values obtained for the distal segment of the sural
      nerve varied widely and in seven apparently normal subjects no SAP could be
      distinguished. In the proximal segment conduction velocities were over 40 m/s and
      there was no significant change with age, unlike the median nerve in which a
      highly significant slowing occurred with age. Comparison of the results of sural
      and median sensory conduction studies in 300 consecutive patients screened for
      sensory polyneuropathy confirms the value of sural nerve sensory studies as a
      routine screening test, and confirms the belief that the changes in
      polyneuropathy are usually more prominent in lower limb nerves. It is therefore
      suggested that studies of sural sensory conduction form the single most useful
      test in the diagnosis of sensory polyneuropathy.

PMID- 4367409
TI  - Pattern of recruiting human motor units in neuropathies and motor neurone
      disease.
AB  - The pattern of recruiting human motor units in the first dorsal interosseous
      muscle of the hand has been studied in 31 patients with ulnar neuropathies and
      motor neurone disease. Two years after surgical repair of an unilateral complete
      severance of the ulnar nerve, the twitch tensions increased to normal size.
      However, the normal orderly pattern of recruiting motor units of increasing size
      during increasing voluntary contractions was irretrievably lost. Among patients
      with pressure or entrapment neuropathies, the normal orderly pattern of
      recruiting motor units was always retained. Similarly, in patients with motor
      neurone disease (amyotrophic lateral sclerosis), the orderly pattern of
      recruitment was not disrupted.

PMID- 4367410
TI  - Nephroblastoma in a bovine fetus.

PMID- 4367411
TI  - Ultrastructure of canine carotid body and aortic body tumors. Comparison with
      tissues of thyroid and parathyroid origin.

PMID- 4367412
TI  - Ultrastructure of normal and neoplastic mast cells of the cat.

PMID- 4367413
TI  - Aortic body tumor in a white rat.

PMID- 4367414
TI  - Cyclic adenosine-3',5'-monophosphate in cellular immunity.

PMID- 4367415
TI  - [Metabolism of hexuronides and hexuronates in Escherichia coli K12: physiologic
      and genetic aspects of its regulation].

PMID- 4367416
TI  - Preliminary analysis of the effects of ATP-Mg on Escherichia coli K 12
      aspartokinase I-homoserine dehydrogenase I, at low potassium concentration.

PMID- 4367417
TI  - [Study of sub-units of high density lipoproteins of human serum after partial
      delipidation].

PMID- 4367418
TI  - Congenital hyperphosphatasia.

PMID- 4367419
TI  - [Acute viral hepatitis in man].

PMID- 4367420
TI  - The action of barbiturates upon liver alcohol dehydrogenase. Their interference
      with alcohol metabolism.

PMID- 4367421
TI  - Action of proteolytic and glycolytic enzymes on the permeability of the blood
      brain barrier.

PMID- 4367422
TI  - Activity of inactivated Burcella on murine tumors: prophylactic effects and
      combination with specific immunostimulation.

PMID- 4367423
TI  - Experiences with a lyophilised contagious bovine pleuropneumonia vaccine in the
      Ivory coast.

PMID- 4367424
TI  - Isolation and characterization of a novel lipid, 1(3),2-diacylglyceryl-(3)-O-4'
      (N,N,N-trimethyl)homoserine, from Ochromonas danica.

PMID- 4367425
TI  - Stimulation of alkaline phosphatase by analogs of inorganic pyrophosphate.

PMID- 4367426
TI  - Kinetic and magnetic resonance studies of the interaction of oxalate with
      pyruvate kinase.

PMID- 4367428
TI  - Quantitative interaction of Ricinus communis agglutinin and concanavalin A with
      influenza and vesicular stomatitis viruses and virus-infected normal and polyoma
      transformed cells.

PMID- 4367427
TI  - Magnetic resonance studies of the active-site region of thermolysin.

PMID- 4367429
TI  - Antibodies to the codons ApApAp, ApApC, and ApUpG.

PMID- 4367430
TI  - Stepwise degradation of polyribonucleotides.

PMID- 4367431
TI  - Chemical probes of chromatin structure.

PMID- 4367432
TI  - Canine malignant mammary tumours. I. Sarcomas.

PMID- 4367433
TI  - The relevance of the superoxide anion radical in biological systems.

PMID- 4367434
TI  - The biological activity and the binding affinity of modified insulins determined
      on isolated rat fat cells.

PMID- 4367435
TI  - Mesenchymal tumors of the uterus.

PMID- 4367436
TI  - Pathophysiology of the Fallopian tube.

PMID- 4367437
TI  - Complications of regional anesthesia in obstetrics.

PMID- 4367438
TI  - [Importance of catecholamines in the physiology and pathology of childhood].

PMID- 4367439
TI  - [Treatment of hyperlipoproteinemias (author's transl)].

PMID- 4367440
TI  - [The quantitative evaluation of lipid spectrum in population studies (author's
      transl)].

PMID- 4367443
TI  - [Peripheral necrotic lesions in scleroderma].

PMID- 4367441
TI  - Some kinetic and inhibition properties of human brain mitochondrial monoamine
      oxidase (EC 1.4.3.4).

PMID- 4367442
TI  - [Invasive malaria with hemoglobinuric bilious fever. Apropos of a fatal case].

PMID- 4367444
TI  - [Indications for neurosurgery in cancerology].

PMID- 4367445
TI  - [Bronchial obstruction following pulmonary embolism].

PMID- 4367446
TI  - [Editorial: Remarks concerning tuberculosis observed during 2 years in a
      hospital].

PMID- 4367447
TI  - Fibers projecting onto the crista ampullaris of the vertical anterior
      semicircular canal from other ipsilateral vestibular receptors in the frog (Rana
      esculenta).

PMID- 4367448
TI  - [An example of the so-called Krukenberg tumor of primary ovarian origin].

PMID- 4367449
TI  - Malignant liver tumors in children.

PMID- 4367450
TI  - Effects of some coenzymes and metabolic factors on experimintal atherosclerosis
      in animals.

PMID- 4367451
TI  - Cytochrome c.

PMID- 4367452
TI  - Effects of 3', 5'-cyclic adenosine monophosphate, 5-hydroxytryptamine,
      noradrenaline and theophylline on the simultaneous release of peroxidase and
      amylase from the guinea pig submanibular gland.

PMID- 4367454
TI  - Pituitary and plasma concentrations of adrenocorticotrophin, growth hormone,
      vasopressin and oxytocin in fetal and maternal sheep during the latter half of
      gestation and the response to haemorrhage.

PMID- 4367453
TI  - Virus infections in bats.

PMID- 4367455
TI  - In vivo metabolism of 14C-labeled palmitic acid in serum and in brown and white
      adipose tissue of well-fed and starved newborn rabbits. II. Tracer kinetic
      analysis of the incorporation rate of serum free fatty acids into the main lipid
      fractions of brown and white adipose tissues.

PMID- 4367456
TI  - Unsuspected tumors in aircraft accident fatalities as a guide to evaluation of
      physical-examination standards.

PMID- 4367457
TI  - Use of immunoperoxidase for the rapid identification of human myxoviruses and
      paramyxoviruses in tissue culture.
AB  - The immunoperoxidase method, using commercially available antisera, was compared
      with standard virological methods for the identification and typing of 77
      isolates of human myxoviruses and paramyxoviruses. Results of typing using
      neutralization tests and the immunoperoxidase technique were identical for 76 of
      the 77 isolates. With the immunoperoxidase method there was one false negative
      reaction, but no false positive reactions. Cross-reactivity between influenza A
      (soluble) and A(2)/HK antisera with influenza A isolates was noted, but did not
      interfere with the interpretation of results. It is concluded that the
      immunoperoxidase method is ideally suited for the rapid identification and typing
      of common human respiratory viruses on a routine basis. It offers a number of
      decided advantages over both immunofluorescence and standard virological methods.

PMID- 4367458
TI  - Biophysical-immunological assay for ribonucleic acid type C viruses.
AB  - A biophysical and immunological method for characterization of ribonucleic acid
      type C virus suspensions is described. The method provides a relationship to the
      total viral mass concentration of the particle titer, the gs antigen titer, and
      the ultraviolet absorbance (268 nm) of 2% sodium dodecyl sulfate digests. Data
      for murine, rat, feline, and hamster viruses are shown to be analogous within the
      test limitations. From these data, an assessment of the viral purity can be made,
      the structural integrity can be evaluated, an approximate molecular weight can be
      computed, and the mole ratio of gs antigen can be determined.

PMID- 4367459
TI  - [Maintenance of differentiated steroidogenetic functions by isolated adrenal
      cells from newborn rats in monolayer culture].

PMID- 4367460
TI  - [Demonstration and study of physico-chemical characteristics of a placental
      protein binding cyclic AMPC].

PMID- 4367461
TI  - [Are bradykinin receptors of smooth muscle and adrenal glands different?].

PMID- 4367462
TI  - Biosynthesis of nitrogenous phospholipids in spinach leaves.

PMID- 4367463
TI  - Preparation and properties of purified (Na+ plus K+)-stimulated mitochondrial
      ATPase from germinating pea seeds.

PMID- 4367464
TI  - Glycosphingolipids in secondary lysosomes prepared from rat liver.

PMID- 4367466
TI  - [Pneumonias of pigs and their etiological complexity].

PMID- 4367465
TI  - [Etiology and pathogenesis of various respiratory tract infections in cattle
      diagnosed in Czechoslovakia].

PMID- 4367467
TI  - Ultrastructural findings in a well-differentiated hepatoma.

PMID- 4367468
TI  - Quantitative hepatic cytology. Experimental study.

PMID- 4367469
TI  - [Hypertrophic radiotherapeutic myelopathies. Apropos of 5 cases with anatomo
      clinical description in 1].

PMID- 4367470
TI  - [Study of infection in primary calf kidney cells by infectious bovine
      rhinotracheitis virus (IBR) using immunofluorescence].

PMID- 4367471
TI  - Herpes encephalitis.

PMID- 4367472
TI  - Electroencephalographic patterns in herpesvirus encephalitis.

PMID- 4367473
TI  - [Acute hydrocyanic acid intoxication. Current data on the metabolism of cyanide
      and treatment by hydroxocobalamin].

PMID- 4367474
TI  - Purification and partial characterization of an endonuclease from Palaemon
      serratus hepatopancreas.

PMID- 4367475
TI  - [Extragonadal endocrine repercussions of long-term estro-progestational
      treatment].

PMID- 4367476
TI  - [Paraneoplastic syndromes with polyendocrine manifestations].

PMID- 4367477
TI  - [Repercussions of thyroid diseases on adrenocortical function].

PMID- 4367479
TI  - Pancreatic islet cell carcinoid: a highly malignant form of carcinoid tumor.

PMID- 4367478
TI  - [New data on the respective behavior of the CRF-ACTH and ACTH-cortisol secretory
      stages in normal subjects and in certain endocrine diseases].

PMID- 4367480
TI  - Culturing breast tumor cells in the presence of hormones.

PMID- 4367482
TI  - Solitary glomus tumours of the fingers.

PMID- 4367481
TI  - Theory of chromatography of rigid molecules on hydroxyapatite columns with small
      loads. I. The case when virtually all molecules are adsorbed on to a single type
      of crystal site through a single type of adsorption group.

PMID- 4367483
TI  - Proceedings: Ectopic parathyroid hormone-producing tumors.

PMID- 4367484
TI  - Proceedings: An autopsy case of cholangiocarcinoma associated with
      pseudohyperparathyroidism.

PMID- 4367485
TI  - Proceedings: Effect of dibutyryl cyclic AMP on the formation of dentin and bone
      in parathyroidectomized rats.

PMID- 4367486
TI  - Rescue of defective SV40 from a transformed mouse 3T3 cell line: selection of a
      specific defective.

PMID- 4367487
TI  - Properties of the ts3 mutant of polyoma virus during lytic infection.

PMID- 4367488
TI  - Inhibitors of DNA synthesis: their influence on replication and transcription of
      simian virus 40 DNA.

PMID- 4367489
TI  - Mapping temperature-sensitive mutants of simian virus 40: rescue of mutants by
      fragments of viral DNA.

PMID- 4367490
TI  - Correlation between amino acid exchanges in coat protein of TMV mutants and the
      nature of the mutagens.

PMID- 4367491
TI  - Molecular weights of plant viral RNAs determined by gel electrophoresis under
      denaturing conditions.

PMID- 4367493
TI  - High specific infectivity avian RNA tumor viruses.

PMID- 4367492
TI  - Regulation of synthesis of herpes simplex type 1 virus mRNA during productive
      infection.

PMID- 4367494
TI  - RNA tumor viruses of pheasants: characterization of avian leukosis subgroups F
      and G.

PMID- 4367495
TI  - Hemagglutinating activity of bovine papilloma virus.

PMID- 4367496
TI  - Defective interfering particles from poliovirus vaccine and vaccine reference
      strains.

PMID- 4367497
TI  - Simian virus 40 structural proteins: amino-terminal sequence of the major capsid
      protein.

PMID- 4367498
TI  - Hybridization of simian virus 40 complementary RNA with nucleolus-associated DNA
      isolated from simian virus 40-transformed Chinese hamster cells.

PMID- 4367499
TI  - "Huffer's" neuropathy.

PMID- 4367501
TI  - [General principles of changes in free radical content during neoplastic growth].

PMID- 4367500
TI  - A study of fine structural changes in the cartilage-to-bone transition within the
      developing chick vertebra.

PMID- 4367502
TI  - The control of mastitis.

PMID- 4367503
TI  - Pathogenesis of peptic ulcer.

PMID- 4367504
TI  - [Autoradiography in degenerative diseases of the hip-joint (author's transl)].

PMID- 4367505
TI  - Depression and frequency facilitation at a synapse in Aplysia californica:
      evidence for regulation by availability of transmitter.

PMID- 4367506
TI  - Potassium-induced release of amino acids from cerebral cortex and spinal cord
      slices of the rat.

PMID- 4367507
TI  - Effects of 6-hydroxydopamine on an identified dopamine-containing neuron in the
      central nervous system of Planorbis corneus.

PMID- 4367509
TI  - The effect of angiotensin II on neurones of the cat subfornical organ.

PMID- 4367508
TI  - Measurements of extracellular potassium, ECoG and pyridine nucleotide levels
      during cortical spreading depression in rats.

PMID- 4367510
TI  - Dynamic patterns of brain cell assemblies. II. Concept of dynamic patterns.
      Dynamic patterns in chemistry.

PMID- 4367511
TI  - Dynamic patterns of brain cell assemblies. II. Concept of dynamic patterns. Cell
      patterning.

PMID- 4367512
TI  - Dynamic patterns of brain cell assemblies. IV. Mixed systems. Interneuronal
      connectivity. Gap junction ultrastructure.

PMID- 4367513
TI  - Dynamic patterns of brain cell assemblies. IV. Mixed systems. Oscillating fields
      and pulse distributions. Relation of neuronal waves to EEG.

PMID- 4367515
TI  - Dynamic patterns of brain cell assemblies. IV. Mixed systems. Oscillating fields
      and pulse distributions. Postsynaptic events.

PMID- 4367514
TI  - Dynamic patterns of brain cell assemblies. IV. Mixed systems. Oscillating fields
      and pulse distributions. Pulse-wave problems.

PMID- 4367516
TI  - Dynamic patterns of brain cell assemblies. IV. Mixed systems. Influence of
      exogenous low-level currents. Electrophysiological effects of direct currents.

PMID- 4367517
TI  - Identification of viruses involved in the 1971 outbreak of hemorrhagic disease in
      southeastern United States white-tailed deer.

PMID- 4367518
TI  - The 1971 outbreak of hemorrhagic disease among white-tailed deer of the
      southeastern United States.

PMID- 4367519
TI  - Vaccination trials in desert bighorn sheep against bluetongue virus.

PMID- 4367520
TI  - Proceedings: Synaptochemistry. Outlines and scope of a discipline.

PMID- 4367522
TI  - Proceedings: Effects of papaverine derivatives on cyclic 3', 5'-AMP
      phosphodiesterase and relaxation of rabbit ileum.

PMID- 4367521
TI  - Proceedings: An attempt to localize cyclic phosphodiesterase at adrenergic nerve
      endings.

PMID- 4367523
TI  - Proceedings: Spinal transmission of autonomic processes.

PMID- 4367524
TI  - Proceedings of the International Neurovegetative Symposium: Concluding remarks.

PMID- 4367525
TI  - [Study in cats with or without motor cortex, or the control of ventrolateral
      thalamic mucleus cells by the substantia nigra].

PMID- 4367526
TI  - General neuropathology of degenerative processes of the nervous system.

PMID- 4367527
TI  - Spontaneous autoimmune diseases of domestic animals.

PMID- 4367528
TI  - Reactivation of chick erythrocyte nuclei by somatic cell hybridization.

PMID- 4367529
TI  - Cyclic AMP levels in temperature sensitive SV40 transformed cell lines.

PMID- 4367530
TI  - Calcium transport in isolated bone cells. I. Bone cell isolation procedures.

PMID- 4367531
TI  - Calcium transport in isolated bone cells. II. Calcium transport studies.

PMID- 4367532
TI  - Studies on a Chinese hamster line that is temperature sensitive for the
      commitment to DNA synthesis.

PMID- 4367533
TI  - Comparative study of various methods for the extraction of free creatine and
      phosphocreatine from mouse skeletal muscle.

PMID- 4367534
TI  - An assay for protein activity on polyacrylamide gels.

PMID- 4367535
TI  - Quantitative measurement of hypermodified adenosine ribonucleosides in plant
      tissues.

PMID- 4367536
TI  - A new rapid assay for measuring deoxycytidylate- and deoxythymidylate-kinase
      activities.

PMID- 4367537
TI  - Acetonitrile-based solvents: their application in thin-layer chromatography of
      cyclic nucleotides, nucleosides, purine, and pyrimidines.

PMID- 4367538
TI  - Experimental herpetic keratitis in the guinea pig.

PMID- 4367540
TI  - Characteristics and distribution of spinal focal synaptic potentials generated by
      group II muscle afferents.

PMID- 4367539
TI  - [Study of the mode of action of dexamethasone used to induce labor in ewes].

PMID- 4367541
TI  - Studies on the postnatal development of the collecting ducts of the rat kidney,
      with particular reference to their glycogen content.

PMID- 4367542
TI  - Ascorbic acid as an antioxidant in thin-layer chromatography of corticosteroids.

PMID- 4367543
TI  - Separation of phosphatidyl inositomannosides of Mycobacteria.

PMID- 4367544
TI  - Lipidosis-like cellular alterations in lymphatic tissues of chlorphentermine
      treated animals.

PMID- 4367545
TI  - Retinal lesions in rat after treatment with chlorphentermine or with tricyclic
      antidepressants.

PMID- 4367546
TI  - Bone marking and lead intoxication. Early pathological changes in osteoclasts.

PMID- 4367548
TI  - Electron microscopic investigation of synaptic organization of the trochlear
      nucleus in cat. I. Normal ultrastructure.

PMID- 4367547
TI  - An ultrastructural analysis of early fertilization in the sand dollar,
      Echinarachnius parma.

PMID- 4367549
TI  - [Endocrine hypertension].

PMID- 4367550
TI  - [Collagenase in the treatment of ulcus cruris].

PMID- 4367551
TI  - Clinicopathological conference: Exanthem and pneumonia in a 3-year-old girl.

PMID- 4367552
TI  - Circumscribed "giant-cell" glioblastoma.

PMID- 4367553
TI  - Giant cell hepatitis with cytomegalovirus inclusions in an adult. A case report.

PMID- 4367554
TI  - Plasma angiotensin-like activity in hypertension.

PMID- 4367555
TI  - [Dental occlusion development in nursery children receiving prophylactic
      treatment against rickets].

PMID- 4367556
TI  - [Unusual complications following implantation of vascular protheses (author's
      transl)].

PMID- 4367557
TI  - [Paraganglioma of the urinary bladder (author's transl)].

PMID- 4367559
TI  - The use of solid medium cultures for the removal of bacteria and fungi from
      Entamoeba histolytica strains.

PMID- 4367558
TI  - [The effect of histones on cytochrome oxidase activity of rabbit reticulocytes].

PMID- 4367560
TI  - Studies on the effect of inactivated viruses on the growth of Poxvirus variolae.
      I. The influence of heating at temperatures: 70 degrees C, 56 degrees C and 37
      degrees C on the infection activity of some viruses.

PMID- 4367561
TI  - Syncytium formation of Japanese quail embryo fibroblasts on double infection with
      Rous sarcoma virus and measles virus.

PMID- 4367562
TI  - Primary tissue culture of brain tumor using glass fiber.

PMID- 4367563
TI  - Vincristine sulphate in the postoperative management of malignant supratentorial
      glioma.

PMID- 4367564
TI  - Combined use of trimethoprim plus superseptyl and of trimethoprim plus
      superseptyl plus polymyxin B in Salmonella infections.

PMID- 4367565
TI  - [Rare vascular tumors of the skin: begign, semi-malignant and malignant (clinical
      evolution, histology, classification)].

PMID- 4367566
TI  - [Mechanism of action and cellular receptors of insulin (author's transl)].

PMID- 4367567
TI  - [Analysis of the possibilities of morphological diagnosis of skeletal
      precancerous conditions and neoplasms according to materials of puncture biopsy].

PMID- 4367569
TI  - [Cace of brain tumor with angiographic presentation of arterial occlusion].

PMID- 4367568
TI  - [Angiography in diseases of the hand and foot in children].

PMID- 4367570
TI  - [Cerebral angiography of the tentorial branch of the internal carotid artery in
      diseases involving the tentorium cerebelli].

PMID- 4367571
TI  - [Diagnosis of brain tumor by encephaloscintigram: with special reference to
      differential diagnosis of glioblastoma and meningioma].

PMID- 4367572
TI  - [Hygienic evaluation of working conditions and state of health of the workers of
      the cyanide process stage at the gold extraction plants].

PMID- 4367573
TI  - [Sexual hormone on the human mammary carcinoma cells in vitro (author's transl)].

PMID- 4367574
TI  - The primary structure of DNA.

PMID- 4367576
TI  - [Difference in facial skin temperature following peripheral or central injury of
      the facial nerve as correlated with electromyographic studies].

PMID- 4367575
TI  - Variola virus in the throat of healthy contacts of small-pox cases.

PMID- 4367578
TI  - A specific method for the assay of alcohol dehydrogenase in human liver and
      serum.

PMID- 4367577
TI  - Treatment and prophylaxis in food handling amoebic cyst carriers.

PMID- 4367579
TI  - [Phosphatase reaction of the striated border of the small intestine of the rat].

PMID- 4367580
TI  - Identification and quantitative determination of 2-hydroxyoestriol in human late
      pregnancy urine.

PMID- 4367581
TI  - Steroid metabolism in testis tissue: concentrations of unconjugated and sulfated
      neutral steroids in boar testis.

PMID- 4367582
TI  - Ligand specificity of progesterone-binding proteins in guinea pig and sheep.

PMID- 4367583
TI  - Physiological variations in plasma testosterone in normal adult male subjects
      measured by a competitive protein-binding technique.

PMID- 4367585
TI  - Binding of progesterone by rat myometrium during pregnancy and by human
      myometrium in late pregnancy.

PMID- 4367584
TI  - Simultaneous determination of cortisol, deoxycortisol and corticosterone in
      plasma and urine by competitive protein binding assay. Response of normal
      subjects to ACTH and metyrapone.

PMID- 4367586
TI  - Characterization of a specific androgen receptor in rat prostate cytosol by
      agargel electrophoresis. In vivo and in vitro studies.

PMID- 4367587
TI  - Blood coagulation and fibrinolysis in Ugandan patients with cirrhosis and
      hepatocellular carcinoma.

PMID- 4367588
TI  - [Effect of ultrasonics on the restoration of functions of parabiotized nerve].

PMID- 4367589
TI  - [Lupus type inclusions. Historical, theoretical, and pratical interest].

PMID- 4367590
TI  - [Transmission of vibrations to the upper limbs].

PMID- 4367591
TI  - Carriers and specificity in membranes. 3. Carrier-facilitated transport.
      Molecular motion in phospholipid bilayers and biomembranes.

PMID- 4367593
TI  - Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral
      agents. 2. Tilorone and related bis-basic ethers of fluorenone, fluorenol, and
      fluorene.

PMID- 4367592
TI  - Carriers and specificity in membranes. V. Neuron membranes. Membrane phenomena at
      the synapse.

PMID- 4367594
TI  - Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral
      agents. 3. 2,7-Bis(aminoacyl)fluorenes and -fluorenones.

PMID- 4367595
TI  - Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral
      agents. 4. Bis-basic sulfonamides of anthraquinone.

PMID- 4367596
TI  - The enzymology of cholesterol esterification.

PMID- 4367597
TI  - Phospholipid substrate specificity of purified human plasma lecithin:cholesterol
      acyltransferase.

PMID- 4367598
TI  - Cholesterol esterification by the rat liver Golgi apparatus.

PMID- 4367599
TI  - Studies on enzymatic and molecular properties of lecithin:cholesterol
      acyltransferase.

PMID- 4367600
TI  - In vitro determination of lecithin:cholesterol acyltransferase in plasma.

PMID- 4367601
TI  - Lecithin: cholesterol acyltransferase of human plasma. Role of chylomicrons, very
      low, and high density lipoproteins in the reaction.

PMID- 4367603
TI  - Degradation of high-density lipoproteins (HDL) in vitro.

PMID- 4367602
TI  - Factors determining the concentrations of lysolecithin in plasma and tissues.

PMID- 4367604
TI  - Human plasma high-density lipoprotein composition during the menstrual cycle.

PMID- 4367605
TI  - Isoelectric fractionation of plasma high-density lipoproteins.

PMID- 4367606
TI  - Familial lecithin:cholesterol acyltransferase deficiency--a clinical survey.

PMID- 4367607
TI  - Apolipoproteins and lipoprotein families in familial lecithin: cholesterol
      acyltransferase deficiency.

PMID- 4367608
TI  - Familial lecithin:cholesterol acyltransferase deficiency. Studies on lipid
      composition and morphology of tissues.

PMID- 4367609
TI  - Familial lecithin:cholesterol acyltransferase deficiency. Report of a third
      Norwegian family with two afflicted members.

PMID- 4367610
TI  - Lipid and lipoprotein abnormalities in liver disease: the possible role of
      lecithin: cholesterol acyltransferase deficiency.

PMID- 4367611
TI  - Structural studies on serum lipoproteins in homozygotes and heterozygotes for the
      lecithin:cholesterol acyltransferase deficiency gene.

PMID- 4367612
TI  - Plasma cholesterol esterification in vivo in man.

PMID- 4367613
TI  - Current concepts of cholesterol metabolism and their relationship to
      lecithin:cholesterol acyltransferase.

PMID- 4367614
TI  - Plasma lipoprotein metabolism in familial lecithin:cholesterol acyltransferase
      deficiency.

PMID- 4367615
TI  - [Apropos of glomus tumors].

PMID- 4367616
TI  - [Diminished glucose tolerance and hyperinsulinism due to prolactin secreting
      adenoma].

PMID- 4367617
TI  - [Sulfate reduction and biosynthesis of sulfur containing amino acids (author's
      transl)].

PMID- 4367618
TI  - [Data on the mechanism of pulmonary edema in perfluorotriethylamine poisoning].

PMID- 4367619
TI  - [Characteristics of morphogenesis of silicotic nodule in silicosis induced by
      silicon oxide].

PMID- 4367620
TI  - [Early cancer of the stomach. 2. Pathology].

PMID- 4367621
TI  - Milk inhalation pneumonia: the significance of fat filled macrophages in tracheal
      secretions.

PMID- 4367622
TI  - [Structure and activity of diphteria toxin (author's transl)].

PMID- 4367623
TI  - Clinicopathologic conference: Coexistent congenital cytomegalovirus and
      toxoplasmosis in a newborn infant.

PMID- 4367624
TI  - Bronchogenic carcinoma.

PMID- 4367626
TI  - [Inhibition by interferon of chromosome damage caused by Sendai virus].

PMID- 4367625
TI  - [Laryngeal and pulmonary neoplasms in asbestosis patients (case report)].

PMID- 4367627
TI  - [Therapy of osteodystrophia deformans (Paget's disease)].

PMID- 4367628
TI  - Oxidative haemolysis and Heinz body haemolytic anaemia.

PMID- 4367629
TI  - Delayed incorporation of (75Se)selenomethionine into fibrinogen: its effect upon
      kinetic studies of fibrinogen with (75Se)selenomethionine in rabbits.

PMID- 4367630
TI  - Neuromuscular blocking action of an alkylating local anaesthetic: site of action
      and effects of temperature and calcium ions.

PMID- 4367632
TI  - Solvent exposure of specific nuclei of angiotensin II determined by NMR solvent
      saturation method.

PMID- 4367631
TI  - Genetic complementation after fusion of Tay-Sachs and Sandhoff cells.

PMID- 4367633
TI  - Analysis of specificity of antibodies contained in antiserum against poliovirus
      with mutants resistant to inhibitors in equine serum.

PMID- 4367634
TI  - On-filter analysis of quartz in respirable coal dust by infrared absorption and X
      ray diffraction.

PMID- 4367636
TI  - Comparative evaluation of cyclacillin and ampicillin in urinary tract infections.
      A double-blind study.

PMID- 4367635
TI  - Therapeutic action of antimicrobial agents in localized infections of mice.

PMID- 4367637
TI  - Pre- and postoperative treatment of chronic multiresistant cases of pulmonary
      tuberculosis with rifampicin.

PMID- 4367638
TI  - [Independance of the binding site for the hormone and of interaction sites with
      chromatin of the uterine receptor for estradiol: demonstration by controlled
      proteolysis].

PMID- 4367639
TI  - Atypical warts in cattle.

PMID- 4367640
TI  - Ulcerative esophagitis associated with poxvirus infection in a calf.

PMID- 4367641
TI  - Biochemical characteristics of mammalian brain 5-hydroxytryptophan decarboxylase
      activity.

PMID- 4367642
TI  - Role of active transport of tryptophan in the control of 5-hydroxytryptamine
      biosynthesis.

PMID- 4367643
TI  - The role of serotonin in the regulation of a phasic event of rapid eye movement
      sleep: the ponto-geniculo-occipital wave.

PMID- 4367645
TI  - Ventricular fluid 5-hydroxyindoleacetic acid concentrations during human sleep.

PMID- 4367644
TI  - On the effects of melatonin on sleep and behavior in man.

PMID- 4367646
TI  - Effects of central alterations of serotoninergic neurons upon the sleep-waking
      cycle.

PMID- 4367647
TI  - Opposite effects of serotonin and dopamine on copulatory activation in castrated
      male rats.

PMID- 4367649
TI  - Serotonergic-dopaminergic interactions and extrapyramidal function.

PMID- 4367648
TI  - Melatonin: effects on brain function.

PMID- 4367651
TI  - [Observations by electron microscopy of 5'-nucleotidase activity at the level of
      biliary canaliculi and of plasma membranes isolated from mouse liver].

PMID- 4367650
TI  - Radioimmunoassay of porcine FSH.

PMID- 4367653
TI  - [Ultrastructural analysis of the peritumoral infiltrate accompanying malignant
      primary melanoma of superficial extensive type].

PMID- 4367652
TI  - [Differentiation of the external segment of cells from the sensory line in
      embryonic epiphysis cerebri of Lacerta vivipara J. (Reptilia; Lacertilia)].

PMID- 4367654
TI  - The pathogenesis of recurrent infections with infectious bovine rhinotracheitis
      virus induced in calves by treatment with corticosteroids.

PMID- 4367655
TI  - An outbreak of bovine cutaneous fibropapillomas following dehorning.

PMID- 4367656
TI  - [Carotid glomus tumors].

PMID- 4367657
TI  - Americans love hogwash.

PMID- 4367658
TI  - Megavitamin and orthomolecular therapy in psychiatry.

PMID- 4367659
TI  - Radioiodine metabolism in endemic goitre in Nigeria. (Significance of the
      perchlorate discharge test).

PMID- 4367660
TI  - Advantages of intertrochanteric osteotomy in osteoarthrosis of the hip.

PMID- 4367661
TI  - Case report: pseudo-tumor of the liver in hepatitis.

PMID- 4367662
TI  - The use of the Langner's Psychiatric Impairment Scale in a student health
      service.

PMID- 4367664
TI  - Group after-care for employed problem drinkers.

PMID- 4367663
TI  - Administrative relationships between maternal and child health programs and
      family planning programs in health departments--1973.

PMID- 4367665
TI  - A treatment for cold sores.

PMID- 4367666
TI  - Cosmetics: is new legislation needed?

PMID- 4367667
TI  - Cosmetics: marketing practices and the Federal Trade Commission.

PMID- 4367668
TI  - Cosmetic legislation: the need.

PMID- 4367669
TI  - Remarks on proposed cosmetic legislation pending in Congress.

PMID- 4367670
TI  - [Relations of cytomegalic inclusion-body disease to pulmonary pathology (author's
      transl)].

PMID- 4367671
TI  - Inactivation of poliovirus in water by ozonation.

PMID- 4367673
TI  - [Can long term patients be rehabilitated?].

PMID- 4367672
TI  - [Lymphographic study of the thyroid gland].

PMID- 4367674
TI  - Inhibition of replication of vesicular stomatitis virus in mouse embryonic cell
      culture infected with Japanese encephalitis virus.

PMID- 4367675
TI  - [Bedside nursing. Approach in after-care in psychiatric nursing].

PMID- 4367676
TI  - [Uncertainty about the care of patients after hospital discharge].

PMID- 4367677
TI  - [Cosmetics for men].

PMID- 4367678
TI  - [Total body cosmetics and preventive health].

PMID- 4367679
TI  - [Cosmetics as a therapeutic medium in psychiatry].

PMID- 4367680
TI  - [Skin disorders as a psychosomatic problem].

PMID- 4367681
TI  - [Skin tests. Methods, significance and evaluation in relation to allergy
      diagnosis].

PMID- 4367682
TI  - [Types of skin; their classification and care from medical and cosmetic
      viewpoint].

PMID- 4367683
TI  - [Foot grooming in diabetics].

PMID- 4367684
TI  - [Venus in a nettle bath].

PMID- 4367685
TI  - [Beat and cosmetics in the sanatorium].

PMID- 4367686
TI  - Antiviral effect of 3, 4-dihydro-1-isoquinolineacetamide hydrochloride in
      experimental human rhinovirus infection.
AB  - Double-blind trials were conducted in volunteers to evaluate the efficacy of the
      prophylactic 3,4-dihydro-1-isoquinolineacetamide hydrochloride (DIQA) treatment
      against rhinovirus type 24 challenge. Ten men received a 7-day course of DIQA
      treatment and 11 men received a placebo. The intranasal viral challenge dose was
      10 mean tissue culture infective doses. The oral administration of 1 g
      prechallenge and 2 g a day for 6 consecutive postchallenge days did not prevent
      the development of colds. Nine drug-treated men and 10 controls developed
      rhinovirus illness. However, the illnesses of the drug-treated men were mild.
      Rhinorrhea occurred less frequently and was more mild in the drug-treated group.
      The challenge virus was recovered from 80% of these subjects in both groups, but
      almost twice the number of challenge viruses were isolated from the controls than
      from the drug-treated men. The prophylactic DIQA therapy appears to suppress the
      cold syndrome and to reduce virus excretion, although its effect is marginal.
      Additional clinical trials are warranted to confirm the antirhinoviral effect of
      this drug.

PMID- 4367687
TI  - Review of the functional neuromuscular transmission unit.

PMID- 4367688
TI  - Rehabilitation through team effort.

PMID- 4367689
TI  - [Tumors of the temporal paraganglion].

PMID- 4367690
TI  - [Usefulness of several methods of investigation in the diagnosis of renovascular
      hypertension].

PMID- 4367691
TI  - [Serum triglyceride changes in diabetes mellitus (pathogenetic and diagnostic
      significance)].

PMID- 4367692
TI  - [Significance of the cancer-leukemia combination].

PMID- 4367693
TI  - [Light and electron microscope appearance of the epithelial lining of epulis].

PMID- 4367694
TI  - Testosterone-activated copulatory behavior in the castrated male rat.

PMID- 4367695
TI  - [Attempt to detect collagenase in the traumatic panus and in autogenous
      osteocartilaginous grafts during incorporation (author's transl)].

PMID- 4367696
TI  - Fetal influences on myometrial contractility.

PMID- 4367698
TI  - Embryonic antigen expression on experimental rat tumours.

PMID- 4367697
TI  - [Theoretical and practical aspects of the problem of peroral immunization at the
      present time].

PMID- 4367699
TI  - [The nurse as a therapeutic reference person and the postreatment arrangement
      practiced by the model station of the psychosomatic clinic, Giessen (author's
      transl)].

PMID- 4367700
TI  - [Influence of angiotensin II-infusion on the sodium- and potassium level in
      plasma and erythrocytes of normotensive persons and patients with essential
      hypertension (author's transl)].

PMID- 4367701
TI  - Myasthenia gravis.

PMID- 4367702
TI  - [Importance of the study of corticotropin circadian rhythm in the functional
      symptomatology of the ACTH-adrenal axis].

PMID- 4367704
TI  - Bronchogenic carcinoma in the presence of heart disease: a diagnostic dilemma.

PMID- 4367703
TI  - [Changes in the plasma angiotensin II activities during the menstruation cycle].

PMID- 4367705
TI  - Changes in 32P-content of phosphatidic acid and the phosphoinositides of rabbit
      platelets during aggregation induced by collagen or thrombin.

PMID- 4367706
TI  - Histochemical findings on preleukemic states.

PMID- 4367707
TI  - Nitroxides. 58. Structure of steroidal spin labels.

PMID- 4367708
TI  - Ornithine decarboxylase turnover slowed by alpha-hydrazino-ornithine.

PMID- 4367709
TI  - The influence of dichlorodiphenyltrichloroethane, polychlorinated biphenyls and
      anionic amphiphilic compounds on stabilization of sodium- and potassium-activated
      adenosine triphosphatases by acidic phospholipids.

PMID- 4367710
TI  - ACTH and alpha-MSH: cardiovascular and antiarrhythmic properties.

PMID- 4367711
TI  - [The thyrotropin response to hypothalamic TRH in some extra-thyroid pathological
      conditions: simple obesity, Paget's disease, endocrine exophthalmos without
      thyrotoxicosis].

PMID- 4367712
TI  - Increasing the resistance of carp to dropsy by breeding. I. Methods of breeding
      for resistance.

PMID- 4367713
TI  - Genetic control of the sensitivity of Aspergillus nidulans to mutagenic factors.
      II. The sensitivity of uvs mutants to different mutagenic factors.

PMID- 4367714
TI  - [Comparative polarisation optical studies of ceramic materials reinforced with
      aluminum oxide].

PMID- 4367715
TI  - [Enterocyte enzymatic activity impairment in lambliasis. Histochemical and
      histopathological study (author's transl)].

PMID- 4367716
TI  - [Effect of metyrapone (SU 4885) on renin-angiotensin-aldosterone system of
      fasting rats].

PMID- 4367717
TI  - 5-Hydroxytryptamine and sleep in the cat: a brief overview.

PMID- 4367718
TI  - [Value of serological tests in infectious mononucleosis (author's transl)].

PMID- 4367719
TI  - Characteristics of a novel serum vitamin-B12-binding protein associated with
      hepatocellular carcinoma.

PMID- 4367720
TI  - Proceedings: The release of plasminogen activator and factor VIII to lysine
      vasopressin, arginine vasopressin, I-desamino-8-d-arginine vasopressin,
      angiotensin and oxytocin in man.

PMID- 4367721
TI  - Glucose intolerance in mice infected with encephalomyocarditis virus.

PMID- 4367722
TI  - Steroid studies in a case of ovarian hyperluteinization with virilism in two
      consecutive pregnancies.

PMID- 4367723
TI  - [Induced hypertension (stages 3 and IV) in patients with chronic peripheral
      arteriopathy (author's transl)].

PMID- 4367724
TI  - Growth of a new fiber projection in the brain of adult rats: Re-innervation of
      the dentate gyrus by the contralateral entorhinal cortex following ipsilateral
      entorhinal lesions.

PMID- 4367726
TI  - Affinity chromatography of beta-hydroxybutyrate dehydrogenase on Nad and
      hydrophobic chain derivatives of sepharose.

PMID- 4367725
TI  - Isolation of synaptic plasma membrane from brain by combined flotation
      sedimentation density gradient centrifugation.

PMID- 4367727
TI  - Nine disease outbreaks associated with myxoviruses among ducks in Hong Kong.

PMID- 4367728
TI  - Effects of phosphate on the dissociation and enzymic stability of rabbit muscle
      lactate dehydrogenase.

PMID- 4367729
TI  - Covalent attachment of fluorescent groups to transfer ribonucleic acid. Reactions
      with 4-bromomethyl-7-methoxy-2-oxo-2H-benzopyran.

PMID- 4367730
TI  - The vitamin-E-deficiency syndrome in pigs. 3. Light- and electron microscopic
      studies on myocardial vascular injuty.

PMID- 4367731
TI  - Canary pox in sparrows and canaries (Fringillidae and in weavers (Ploceidae).
      Pathology and host specificity of the virus.

PMID- 4367732
TI  - Cushing's syndrome secondary to ACTH-secreting Wilms' tumor.

PMID- 4367733
TI  - Coenzyme contents of arterial tissue.

PMID- 4367734
TI  - Dissolution and removal of neuronal lipofuscin following dimethylaminoethyl p
      chlorophenoxyacetate administration to guinea pigs.

PMID- 4367735
TI  - [State of the liver in Itsenko-Cushing syndrome].

PMID- 4367736
TI  - [Symposium on pathophysiology of congestive heart failure. 1. Relationship of
      renin-angiotensin-aldosterone system to cardio-renal hemodynamics on chronic
      congestive heart failure (author's transl)].

PMID- 4367738
TI  - [Multiple primary malignant neoplasms].

PMID- 4367737
TI  - Swellings of the salivary glands. I. Non-neoplastic enlargements.

PMID- 4367739
TI  - [Function of chorda tympani and Bell's paralysis].

PMID- 4367740
TI  - IBR virus isolated from two epizootics in Mexican dairy cattle.

PMID- 4367741
TI  - Letter: Ferroxidase I and II.

PMID- 4367742
TI  - Food faddism.

PMID- 4367743
TI  - Investigation of some biochemical genetic markers in four endogamous groups in
      Panjab (N.W. India). II. Red cell enzyme polymorphisms.

PMID- 4367744
TI  - [Critic study of multiple sclerosis treatment by chlorambucil and intraspinal
      corticotherapy. Apropos of 100 cases followed up from 2 to 9 years].

PMID- 4367745
TI  - The turnover rate of serum glycerides in the lipoproteins of fasting obese women
      during weight loss.

PMID- 4367746
TI  - Aspects of experimental hepatocarcinogenesis. V. Ultrastructural morpholgy of
      early hepatocellular carcinomas.

PMID- 4367747
TI  - Primary liver tumors in infancy and childhood. 41 cases variously treated.

PMID- 4367748
TI  - Vascular problems in upper abdominal cancer surgery.

PMID- 4367749
TI  - Bronchial carcinoma treated by adjuvant cancer chemotherapy.

PMID- 4367750
TI  - The Lockerbie road accident after-care scheme.

PMID- 4367751
TI  - [Instruction as an intervention process and as reflection of the intervention
      process].

PMID- 4367752
TI  - Endocrine changes before and after the menarche. I. Urinary excretion of
      estrogen, FSH and LH, and serum levels of progesterone, FSH and LH.

PMID- 4367753
TI  - Enhancement of the activity of angiotensin II by certain cations.

PMID- 4367754
TI  - Papaverine, a potent inhibitor of respiration in C-6 astrocytoma cells.

PMID- 4367755
TI  - Products, requirements and efficiency of biosynthesis: a quantitative approach.

PMID- 4367756
TI  - [Episodes of clinical manifestations referable to probable involvement of the
      immune system in 2 sisters with myasthenia gravis].

PMID- 4367757
TI  - Formation and biologic role of polyoma virus-antibody complexes. A critical role
      for complement.
AB  - Interaction of polyoma virus, specific antibody, and complement has been studied.
      Firm evidence has been gathered that C1 through C3 and not C5 through C9 enhance
      neutralization of virus-antiviral antibody (V-Ab) complexes. C enhancement of
      neutralization occurs primarily by agglutination of V-Ab complexes and not by
      virion lysis or attachment of large protein molecules to the V-Ab complex. In
      this model, binding of C1, 4, 2, 3 to the V-Ab complex may explain why some
      viruses concentrate in or infect certain cells bearing C3 receptors such as B
      lymphocytes, macrophages, and monocytes.

PMID- 4367759
TI  - Expression of mammary tumor virus antigen on the membranes of lymphoid cells.

PMID- 4367758
TI  - Inhibition of leukocyte migration by human tumors. Effect on patient survival.

PMID- 4367760
TI  - Carcinogenic and hepatotoxic effects of diethylnitrosamine in hedgehogs.

PMID- 4367761
TI  - Cancer control in Yugoslavia.

PMID- 4367762
TI  - Possible viral etiology of human cancer.

PMID- 4367763
TI  - Studies on the effect of fructose diphosphatase on phosphofructokinase.

PMID- 4367764
TI  - Differential effects of pentylenetetrazol on REM sleep in naive and cobalt
      epileptic rats.

PMID- 4367765
TI  - Cytoplasmic inclusions in urinary bladder epithelium of the rhesus monkey. A
      histochemical, light-and electron-microscopic study.

PMID- 4367766
TI  - Proceedings: The role of choline in maintatining the fine structure of nerve
      terminals in the superior cervical ganglion of cat.

PMID- 4367767
TI  - [Patterns of discharge of inspiratory laryngeal motor neurons under various
      experimental conditions].

PMID- 4367769
TI  - [Incidence of antiboides against viruses of infectious bovine rhinotracheitis
      (IBR), parainfluenza (PI-3) and mucosal disease (VDV) in young cattle herds in
      the region of south western Slovakia].

PMID- 4367770
TI  - Light and electron microscopic study of unfertilized egg of Ascidia malaca
      (Tunicata).

PMID- 4367768
TI  - Protein and ribonucleic acid metabolism in single-cell suspensions from Morris
      hepatoma 5123tc and from normal rat liver.

PMID- 4367771
TI  - Availability of tryptophan to the brain and some hormonal and drug influences on
      it.

PMID- 4367772
TI  - How important is the synthesis of brain 5-hydroxytryptamine in the physiological
      control of its central function?

PMID- 4367773
TI  - Intrahepatic arterial portal communications: angiographic study.

PMID- 4367774
TI  - Macro-regenerating nodule in the cirrhotic liver. Radiologic features and
      differential diagnosis.

PMID- 4367775
TI  - Localized deformity of the gallbladder secondary to hepatic mass lesions.

PMID- 4367776
TI  - [Isolation of a foreign virus from calf serum].

PMID- 4367777
TI  - Paralytic poliomyelitis in Ontario: laboratory studies of two recent cases.
AB  - Sporadic cases of paralytic poliomyelitis are being reported with increasing
      frequency, particularly in unvaccinated persons, in several countries in which
      the disease had been absent for several years following adequate initial
      vaccination programmes. In Ontario, two paralytic cases occurred in unvaccinated
      children after several disease-free years. Detailed studies of the strains of
      poliovirus type 1 isolated from these patients showed that they were not vaccine
      strains. Contact surveillance in one case showed that 21 originally unvaccinated
      contacts were also excreting virulent virus.

PMID- 4367779
TI  - Ecological studies on the mosquito vectors of Japanese encephalitis.
AB  - These studies were conducted in China (Province of Taiwan) to assess the
      populations of known and potential mosquito vectors of Japanese encephalitis in a
      typical endemic area, and to evaluate a variety of sampling techniques, some of
      which were new. Culex annulus was found to be the predominant vector species in
      the study area during the epidemic season; C. tritaeniorhynchus was never
      abundant, and C. fuscocephalus was rare. C. annulus and C. tritaeniorhynchus were
      active throughout the year, although populations were at a low level during the
      cool season. The results show that attention must be given to C. annulus as a
      possible vector where it is present in JE foci. The collection of mosquitos
      during the early evening hours from buffalo bait tethered outdoors was found to
      be the most efficient and sensitive means of monitoring vector populations
      throughout the year. During the JE epidemic season remarkable results were
      obtained with a vacuum sweep-net.

PMID- 4367778
TI  - Assay of variola virus on microtiter plates and its application to the
      neutralization test.
AB  - It was established that microfocus assay of the variola virus in HeLa cell
      cultures on Microtiter plates is a suitable method for titrating the virus in
      numerous specimens of small volume. The variola foci were formed within 48 hours
      of inoculation, and the standard error for the number of foci per well did not
      exceed 15%, with 96 flat-bottomed wells (6 mm diameter) containing 0.1 ml per
      well of the culture media on a plastic plate replacing 96 Petri dishes in the
      standard assay procedures. Microfocus assay was successfully applied to the
      quantification of neutralizing antibody against variola and vaccinia viruses,
      with a reproducibility equal to that of the standard focus reduction method on
      glass Petri dishes. Applications of this technique to the assay of field
      specimens and to the laboratory differentiation of variola viruses are discussed.

PMID- 4367780
TI  - Host-feeding patterns and behaviour of 4 Culex species in an endemic area of
      Japanese encephalitis.
AB  - Studies were made on the host-feeding patterns and behaviour of 4 Culex species
      in China (Province of Taiwan) to further assess their importance as vectors of
      Japanese encephalitis. A relatively unbiased, non-attractant technique (vacuum
      sweep-net) was used for collecting mosquitos resting outdoors on rural premises;
      blood meals from engorged specimens were identified by precipitin tests.
      Additional information was obtained by analysing data from related studies.
      Precipitin-test results indicated that C. annulus, C. tritaeniorhynchus, and C.
      fuscocephalus feed principally on mammals, the first species mainly on swine and
      the latter two largely on bovine hosts. Mosquito forage ratios suggested that the
      apparent preference of C. annulus for swine over bovine hosts might be a function
      of host density. C. annulus was found to be zoophilic, exophilic, and exophagic;
      however, in view of its abundance during the JE epidemic season, contact with
      human hosts may reach a significant level, even indoors. The other 3 species of
      Culex were considered to be of lesser importance as JE vectors during the 1971
      epidemic season because of their host-feeding patterns and/or population
      densities.

PMID- 4367781
TI  - [Demonstration of several enzymes in the sperm of the carp (Cyprinus carpio
      L.)and the trout (Salmo gairdnerii Richardson) and in the coelomic fluid of the
      trout].

PMID- 4367782
TI  - [Anti-nicotinic effect of papaverine].

PMID- 4367783
TI  - [Clinical observations on dibutyryl cyclic AMP in the treatment of psoriasis].

PMID- 4367784
TI  - [Electron microscopic identification of several respiratory viruses].

PMID- 4367785
TI  - [New drugs used in stomatology].

PMID- 4367786
TI  - [Perfusion scans and myocardial myograms as an addition to selective coronary
      angiograms and laevo-cardiograms. Methods and normal perfusion findings (author's
      transl)].

PMID- 4367787
TI  - [Selective coronary angiography using Diaphyllin as a functional test (author's
      transl)].

PMID- 4367788
TI  - [Percutaneous, transhepatic cholangiography before reexplorations of the biliary
      ducts (author's transl)].

PMID- 4367789
TI  - [Angiographic investigation of the Budd-Chiari syndrome. Case following use of an
      oral contraceptive (author's transl)].

PMID- 4367790
TI  - [Blood supply of the abdominal organs through a single vessel, the truncus
      coeliaco-mesenterico, combined with hypoplasia of the abdominal aorta (author's
      transl)].

PMID- 4367791
TI  - [Demonstration of the A. radicularis magna in abdominal aortograms (author's
      transl)].

PMID- 4367792
TI  - [Haemangiopericytoma of the meninges radiographically considered (author's
      transl)].

PMID- 4367794
TI  - [The results of dose measurements during cerebral angiography, using various
      types of angiographic equipment (author's transl)].

PMID- 4367793
TI  - [Hydrocephalus: the radiology of non-vascular liquor shunts and their
      complications (author's transl)].

PMID- 4367795
TI  - [Clinically occult carcinoma of the breast and the early diagnosis of breast
      cancer (author's transl)].

PMID- 4367796
TI  - [An investigation of the accuracy of mammography--diagnosis without a knowledge
      of the clinical findings (author's transl)].

PMID- 4367797
TI  - [Changes in creatin phosphokinase levels during angiography, with particular
      reference to general anaesthesia (author's transl)].

PMID- 4367798
TI  - [Observations on the absorption of an oily contrast medium (Duroliopaque) after
      myelography (author's transl)].

PMID- 4367800
TI  - [Storage of micro-films: present experience (author's transl)].

PMID- 4367801
TI  - [A rare collateral circulation following thrombosis of vena cava inferior and
      pelvic-bone vein thrombosis left].

PMID- 4367799
TI  - [Myelography using a water-soluble contrast medium without anaesthesia in the
      diagnosis of abnormalities in the lumbo-sacral-region (author's transl)].

PMID- 4367802
TI  - [Solitary plasmacytoma of the duodenum].

PMID- 4367804
TI  - [German standards. Medical x-ray equipment up to 300 kV: radiation protection
      rules for installation. Draft February 1974].

PMID- 4367803
TI  - [Punction syringe for taking out of tissue, especially for lung punctures].

PMID- 4367805
TI  - Association of the uterine 17beta-estradiol-receptor complex with
      ribonucleoprotein in vitro and in vivo.

PMID- 4367806
TI  - Initiator methionine transfer ribonucleic acid from wheat embryo. Purification,
      properties, and partial nucleotide sequences.

PMID- 4367807
TI  - Staphylococcal transfer ribonucleic acids. II. Sequence analysis of isoaccepting
      glycine transfer ribonucleic acids IA and IB from Staphylococcus epidermidis
      Texas 26.

PMID- 4367808
TI  - Functional groups of diphosphopyridine nucleotide-linked isocitrate dehydrogenase
      from bovine heart. Studies of cysteine residues.

PMID- 4367809
TI  - Rotational and segmental motions in the lipids of human plasma lipoproteins.

PMID- 4367810
TI  - Structure and methylation of coenzyme M(HSCH2CH2SO3).

PMID- 4367811
TI  - Soluble cytochrome b-c1 complex and the reconstitution of succinate-cytochrome c
      reductase.

PMID- 4367812
TI  - Physical and kinetic studies of arginyl transfer ribonucleic acid ligase of
      Neurospora. A sequential ordered mechanism.

PMID- 4367814
TI  - Isolation and alignment of the tryptic peptides of alanine apolipoprotein, an
      apolipoprotein from human plasma very low density lipoproteins.

PMID- 4367813
TI  - Cyclic 3':5'-nucleotide phosphodiesterase. Purification, characterization, and
      active form of the protein activator from bovine brain.

PMID- 4367816
TI  - Aflatoxin hepatic carcinogenesis (sequential study in albino rats).

PMID- 4367815
TI  - Phosphorylation of a cyclic adenosine 3':5'-monophosphate-dependent protein
      kinase from bovine cardiac muscle.

PMID- 4367817
TI  - Microbial opportunism in clinical medicine.

PMID- 4367818
TI  - [Climacteric period in men and its therapy (author's transl)].

PMID- 4367819
TI  - [Pharmacological aspects of the prostaglandins].

PMID- 4367820
TI  - The metabolism of vitamin D; recent developments and their clinical relevance.

PMID- 4367822
TI  - [Case of mediastinal chemodectoma].

PMID- 4367823
TI  - [Anaerobic paraproctitis].

PMID- 4367821
TI  - Idiopathic thrombocytopenic purpura.

PMID- 4367824
TI  - [New hormonal factor influencing natriuresis in mammals].

PMID- 4367826
TI  - Etiology and laboratory diagnosis of infectious mononucleosis: I. Epstein-Barr
      virus (EBV) mononucleosis.

PMID- 4367825
TI  - Classification and treatment of seizure disorders in children.

PMID- 4367827
TI  - Etiology and laboratory diagnosis of infectious mononucleosis: II.
      Cytomegalovirus (CMV) mononucleosis.

PMID- 4367828
TI  - Foreign body granuloma of synovium following intra-articular injection.

PMID- 4367829
TI  - Gout and pseudogout established by polarized light microscopy of synovial fluid.
      Methods and two case reports.

PMID- 4367830
TI  - Histogenesis of prostatic carcinomas.

PMID- 4367831
TI  - Cyclic changes in the uterine phosphatases during breeding and non-breeding
      seasons of Hemiechinus auritus collaris Gray, the Indian long-cared hedgehog.

PMID- 4367832
TI  - Virus content of sewage in different seasons in Hungary.

PMID- 4367833
TI  - Intraspecific variation in Plasmodium falciparum.

PMID- 4367834
TI  - Malaria antibody levels in patients with Burkitt's lymphoma.

PMID- 4367835
TI  - The interaction between Entamoeba histolytica and Trichuris muris infections in
      mice.

PMID- 4367836
TI  - Susceptibility of Schistosoma mansoni from Liberia and Puerto Rico to
      antischistosomal drugs.

PMID- 4367837
TI  - [Periodimetry in non-aqueous media: application to the determination of various
      substances of pharmaceutical interest].

PMID- 4367838
TI  - Ultrastructure of polymorphic Mucor as observed by means of freeze-etching. I.
      Vegetative growth of mycelium and arthrospore formation in submerged and aerated
      cultures.

PMID- 4367839
TI  - The presence of unusual microtubular structures in senescent cells of
      Chlamydomonas dysosmos.

PMID- 4367840
TI  - Inorganic polyphosphates and enzymes of polyphosphate metabolism in the cellular
      slime mold Dictyostelium discoideum.

PMID- 4367841
TI  - Cyanide-insensitive respiration in Moniliella tomentosa and the effect of drugs
      on respiration and polyol biosynthesis.

PMID- 4367842
TI  - Treatment of Wilm's tumor. Diagnosis and surgical treatment.

PMID- 4367843
TI  - Treatment of Wilm's tumor. Radiotherapy.

PMID- 4367844
TI  - Treatment of Wilm's tumor. Chemotherapy.

PMID- 4367845
TI  - Cyclic nucleotide binding and protein kinase in the central nervous system of
      Galleria mellonella (L.).

PMID- 4367846
TI  - Measured and calculated NAD+-NADH ratios in human erythrocytes.

PMID- 4367847
TI  - Turnover of hepatic mitochondrial ornithine aminotransferase and cytochrome
      oxidase using (14C)carbonate as tracer.

PMID- 4367848
TI  - Hormonal regulation of collagen degradation in the uterus: inhibition of
      collagenase expression by progesterone and cyclic AMP.

PMID- 4367849
TI  - Catabolite repression of L-arabinose isomerase in Escherichia coli induced by
      ultraviolet irradiation.

PMID- 4367850
TI  - Regulation of growth in vitro. I. Control of ornithine decarboxylase levels in
      untransformed and transformed mouse fibroblasts by serum.

PMID- 4367851
TI  - Structural changes in rat liver endoplasmic reticulum following triiodothyronine
      administration.

PMID- 4367852
TI  - [Tissue sphingomyelins in the chick: in vivo analysis and metabolism].

PMID- 4367853
TI  - [Molecular evolution at the level of proteins].

PMID- 4367854
TI  - [Enterogenons methemoglobinemia caused by heterozygotic deficiency of
      erythrocytic NADH-methemoglobin reductase].

PMID- 4367855
TI  - Fluorescence and electron microscopical study of aminergic nuclei in the brain of
      Bufo poweri.

PMID- 4367856
TI  - Origin and fate of the multivesicular bodies in PHA stimulated lymphocytes.

PMID- 4367857
TI  - A quantitative study of the ultrastructural changes in the hypothalamo
      neurohypophysial system during and after experimentally induced hypersecretion.

PMID- 4367858
TI  - Structure and ultrastructure of the central nervous system of the polychaete
      Nephtys, with special reference to photoreceptor elements.

PMID- 4367859
TI  - Cholinesterase in the posterior pituitary. Increased number of reactive
      pituicytes in the dehydrated rat.

PMID- 4367860
TI  - Lipidosis-like alterations in hypothalamic neurosecretory cells of rats treated
      with chlorphentermine or iprindole.

PMID- 4367861
TI  - Nerve endings in the arteria centralis retinae.

PMID- 4367862
TI  - Investigations on the fine structure of Purkinje fibres in the atrium of the
      avian heart.

PMID- 4367863
TI  - Ultrastructure of neurohemal organs (paraganglionic plates) of Trogulus
      nepaeformis (Scopoli) (Opiliones, Trogulidae) and release of neurosecretory
      material.

PMID- 4367864
TI  - Ivestigations on adrenocortical mitochondria turnover. I. Effect of chronic
      treatment with ACTH on the size and number of rat zona fasciculata mitochondria.

PMID- 4367865
TI  - Ultrastructure of mucosal mast cells in normal and compound 48-80-treated rats.

PMID- 4367866
TI  - [Development of complement fixation antibodies against Cytomegaloviruses in early
      childhood and its long-term follow-up].

PMID- 4367867
TI  - Anti-DNA virus activity of the 5'-nucleotide and 3',5'-cyclic nucleotide of 9
      beta-D-arabinofuranosyladenine.

PMID- 4367869
TI  - The use of density gradient centrifugation for the separation of serum
      lipoproteins.

PMID- 4367868
TI  - A modified thymol turbidity test in hyperglobulinaemia.

PMID- 4367870
TI  - The use of nitroblue tetrazolium prestaining of serum lipoproteins on
      polyacrylamide disc electrophoresis.

PMID- 4367871
TI  - Hepatic hexokinase isozyme in liver diseases.

PMID- 4367872
TI  - Effect of Al-chlorophenoxyisobutyrate (Alufibrate) on pyruvate metabolism and on
      the fate of very low density lipoprotein lipids in hyperlipidemic patients.

PMID- 4367873
TI  - Possible association between an abnormal low density lipoprotein and nephropathy
      in lecithin: cholesterol acyltransferase deficiency.

PMID- 4367874
TI  - A modified radiochemical assay for serum free fatty acid determination.

PMID- 4367875
TI  - Effect of lipoic acid on tissue respiration in rabbits with experimental
      atherosclerosis.

PMID- 4367876
TI  - [Clofibrate in diabetes insipidus (author's transl)].

PMID- 4367877
TI  - Mutants of yeast defective in iso-1-cytochrome c.
AB  - A medium containing chlorolactate has been devised to enrich for mutants that are
      unable to utilize lactate for growth, and therefore that may be defective in
      cytochrome c. Complementation tests of 6,520 chlorolactate-resistant mutants that
      were obtained spontaneously or induced with UV, ICR-170, or nitrosoimidazolidone
      resulted in the identification of 195 mutations at the cyc1 locus, which controls
      the primary structure of iso-1-cytochrome c. These 195 mutants, with 16 cyc1
      mutants previously isolated, were examined for total cytochrome c by
      spectroscopic methods, growth on lactate medium, suppressibility by defined
      nonsense suppressors, mutational sites by x-ray-induced recombination, ability to
      revert, and in 86 cases, whether intragenic revertants contain altered iso-1
      cytochrome c. Except for the deletion mutant cyc1-1, all of the mutants appeared
      to contain single-site mutations that could be assigned to at least 35 different
      sites within the gene. The cyc1 mutants either completely lacked iso-1-cytochrome
      c or contained iso-1- cytochromes c that were completely or partially
      nonfunctional. In spite of the fact that the cyc1 mutants obtained by the
      chlorolactate procedure were selected on the basis of defective function, 68%
      appeared to completely lack iso-1-cytochrome c. The remaining cyc1 mutants
      contained below normal amounts of iso-1-cytochromes c. Studies at several
      incubation temperatures indicated that these nonfunctional iso-1-cytochromes c
      were thermolabile. It is suggested that the predominant means for abolishing iso
      1-cytochrome c by mutations are either through a complete loss, such as produced
      by chain terminating codons, or impairments through drastic changes of tertiary
      structure which lead to instability and thermolability.

PMID- 4367878
TI  - Comparison of the frequencies of spontaneous and chemically-induced 5
      bromodeoxyuridine-resistance mutations in wild-type and revertant BHK-21-13
      cells.
AB  - 5-bromodeoxyuridine resistance mutations induced by mutagenesis were studied. The
      average expression time for induced mutations varied with the concentration of
      the mutagen ethyl methanesulfonate (EMS). However, a constant number of two
      generation times was necessary for half maximal expression of induced mutations.
      Also, induced mutation rates were compared under optimal expression conditions
      for bromodeoxyuridine, fluorodeoxyuridine and azaguanine resistance markers. Ten
      independent bromodeoxy-uridine-resistant clones were tested for reversion. Two
      clones reverted-one spontaneously and the other after mutagenesis. The
      spontaneous rate of mutation to bromodeoxyuridine resistance, estimated by the
      fluctuation test, was high in revertant clones (4 x 10(-6) / cell / generation)
      and low in the wild-type cells (< 3.5 x 10(-8) / cell / generation). A comparison
      of induced mutation frequencies at variable EMS concentrations showed a single
      hit curve for revertant clones and a multihit curve for the wild-type cells.
      Thymidine kinase activities of resistant clones were usually less than 2% of that
      of the wild-type clone. Inducibility, thermal stability and intracellular
      localization of the thymidine kinases of the wild-type cells and of a revertant
      clone were identical. A low, but significant (P < 0.10), Km discrepancy was
      observed between enzyme extracts of these lines. The genetic implications of
      these results are discussed.

PMID- 4367879
TI  - Localization of 3', 5'-cyclic nucleotide phosphodiesterase activity in isolated
      thyroid cells and intact thyroid tissue.

PMID- 4367880
TI  - [Overactivity of the indophenol oxidase (form dimeric) in the trisomy 21,
      secondary to triplicated gene (author's transl)].

PMID- 4367881
TI  - An affinity column method for partial purification of cytochrome P-450 from
      phenobarbital-induced rabbit liver microsomes.

PMID- 4367882
TI  - Nuclear phosphoprotein kinases from rat liver.

PMID- 4367883
TI  - Reactivity of peptide imino groups in proteins with tert-butyl hypochlorite in
      relation to secondary structure.

PMID- 4367884
TI  - Phosphodiesterase-phosphomonoesterases from Fusarium moniliforme. IV. Kinetic
      studies.

PMID- 4367885
TI  - N-acyl specificity of Taka-N-acetyl-beta-d-glucosaminidase. IV. Essential
      requirement of the 2-acetamide-carbonyl group for the enzymatic hydrolysis.

PMID- 4367886
TI  - Malignant fibrous histiocytoma and osteosarcoma in association with bone
      infarcts; report of four cases, two in caisson workers.

PMID- 4367887
TI  - Effects of colchicine and vinblastine on the cellular action of vasopressin in
      mammalian kidney. A possible role of microtubules.
AB  - To evaluate the possible role of microtubules in the cellular action of
      vasopressin on the mammalian kidney, the effects of microtubule-disrupting agents
      were studied in vivo and in vitro. In vivo studies were done in rats in mild to
      moderate water diuresis induced by drinking 5% glucose. Microtubule-disrupting
      alkaloids, colchicine (0.1 mg/day) or vinblastine (0.08 mg/day), given
      intraperitoneally, did not change water and solute excretion itself, but blocked
      or markedly inhibited the antidiuretic response (increase in urine osmolality and
      decrease in urine flow) to exogenous vasopressin. Total solute excretion was
      unaffected by these two alkaloids and there were no substantial changes in
      excretion of sodium, potassium, or creatinine. Lumicolchicine, a derivative of
      colchicine that does not interact with microtubules, did not alter the
      antidiuretic response to exogenous vasopressin. Activities of adenylate cyclase
      in the renal medullary plasma membrane, and cyclic AMP phosphodiesterase and
      protein kinase in renal medullary cytosol, were not influenced by 10(-5)-10(-4) M
      colchicine or vinblastine in vitro. Studies on the subcellular distribution of
      microtubular protein (assessed as [(3)H]colchicine-binding protein) in renal
      medulla shows that this protein is contained predominantly in the cytosol.
      Particulate fractions, including plasma membrane, contain only a minute amount
      (less than 6%) of the colchicine-binding activity. The results suggest that the
      integrity of cytoplasmic microtubules in cells of the distal nephron is required
      for the antidiuretic action of vasopressin, probably in the sites distal to
      cyclic AMP generation in the mammalian kidney.

PMID- 4367888
TI  - Utilization of alpha-keto and alpha-hydroxy analogues of valine by the growing
      rat.
AB  - When 70-80-g male albino rats eat a diet furnishing daily requirement of valine
      for optimal growth (70 mumol/g) and all other nutrients ("complete diet"), they
      gain weight at an average rate of 3.0 g/100 g body wt/day. When valine is
      removed, they lose weight at an average 2.1 g/100 g body wt/day. The growth
      retardation is improved or corrected by adding valine to the diet, daily weight
      gain being proportional to dietary valine content over a range of 0-70 mumol/g.
      Addition of alpha-ketoisovaleric acid instead of valine to the valine-free diet
      also improves or corrects the growth failure. Percent efficiency of alpha
      ketoisovaleric acid as a substitute for valine was calculated as: 100 x
      (micromole valine per gram diet required to produce specified growth
      response)/(micromole alpha-ketoisovaleric acid per gram diet required to produce
      the same response). Efficiency of the substitution is inversely related to
      dietary content of the keto analogue, being 80% when diet contains 17.5 mumol/g
      (molar equivalent of (1/4) the daily requirement of valine), and 37% when diet
      provides 140 mumol/g (molar equivalent of twice the daily requirement of
      valine).alpha-Hydroxyisovaleric acid also substitutes for valine. Efficiency of
      the substitution at the single ration tested, 70 mumol/g diet, is 45%, similar to
      that for the keto analogue under the same conditions. When [1-(14)C]alpha
      ketoisovaleric acid is injected intravenously, 30-80% of the administered
      radioactivity is exhaled as (14)CO(2) within 24 h. This finding suggests that
      inefficiency of alpha-ketoisovaleric acid as a substitute for valine results in
      part from degradation of the keto acid to isobutyric acid by branched chain
      dehydrogenase-decarboxylase. Oral administration of neomycin, polymyxin, and
      bacitracin reduces efficiency of alpha-ketoisovaleric acid as a substitute for
      valine by (1/4)-(1/2). This effect suggests that transamination of the keto acid
      may be performed in part by gastrointestinal microbes.

PMID- 4367889
TI  - The turnover of cholesterol in human atherosclerotic arteries.
AB  - The equilibration of cholesterol between plasma and atherosclerotic arteries was
      studied in 13 patients with obstructive atherosclerosis 2-96 days after the
      intravenous and/or oral administration of isotopic cholesterol. Arterial
      specimens were obtained in 12 patients during surgery for arterial reconstruction
      and in a 13th patient at autopsy. Equilibration was calculated as the specific
      radioactivity of cholesterol in the arterial tissue relative to that in the
      plasma (percent).In specimens obtained 2-4 days after pulse labeling, the
      specific activity of cholesterol in atheroma ranged from 0.3 to 4.5% of that in
      the plasma. By 17-27 days, the relative specific activity ranged from 6 to 20% in
      different arteries. In contrast, cholesterol of skeletal muscle had a relative
      specific activity of 96% by 22 days. By 61-96 days, atheroma cholesterol in the
      abdominal aorta, common iliac, and femoral arteries had equilibrated to 55, 30,
      and 26%, respectively. In the patient who died at 96 days, the cholesterol in the
      coronary arteries had a mean equilibration of 66%, similar to the values for the
      abdominal (66%) and thoracic (57%) aortas. The route of administration of the
      isotope did not influence the equilibration. Within the atheromatous plaque, the
      superficial layers equilibrated better than the deeper layers (75% vs. 22%). The
      free cholesterol in the atheroma equilibrated to a significantly higher extent
      than did esterified cholesterol (59% vs. 38%). There was a fourfold higher
      specific activity of cholesterol in the media than in the corresponding intima
      (916 vs. 230 dpm/mg). The estimated minimal influx rates of plasma cholesterol
      into the atheromatous intima ranged from 0.065 to 0.274 mg of cholesterol/g dry
      tissue per day for different arteries. The approximated turnover times of
      atheroma cholesterol ranged from 442 days for the abdominal aorta and the
      coronary arteries to 580 days for the common iliac and 821 and 934 days,
      respectively, for the femoral and the carotid arteries. These data indicate a
      definite, though slow, exchange of cholesterol between the plasma and severely
      atherosclerotic human arteries. Within the atheroma, there are multiple pools of
      cholesterol, each turning over differently and more slowly than the cholesterol
      of most other tissues, such as the skeletal muscle. The estimates of influx rate
      and turnover time of atheroma cholesterol suggest the possibility that this
      cholesterol is mobilizable, an indication of potential regression of atheromatous
      lesions in man.

PMID- 4367890
TI  - Release of prostaglandin by mitogen- and antigen-stimulated leukocytes in
      culture.
AB  - The prostaglandin (PG) content of mitogen- and antigen-stimulated leukocyte
      cultures was examined by a radioimmunoassay procedure empolying an antiserum
      reactive with PGB(1) and PGB(2), the alkaline dehydration products of PGE and
      PGA. At 48 h, mitogen-activated mouse spleen cell cultures showed 2-10-fold
      increases in the PGE, but not in the PGA, component of immunoreactive PG (iPG)
      fractionated by silicic acid column chromatography. Increases in iPG were
      detectable by h 16 in spleen cell cultures incubated with staphylococcal
      enterotoxin B. Since iPG levels rose only in the culture supernates and not in
      cells exposed to mitogens for 48 h, increases reflected extracellular release of
      PG. The validity of the radioimmunoassay determinations of PGE in spleen cell
      cultures was supported by the results of concomitant assessment of the PGE(2)
      content of basal and enterotoxin-stimulated cultures by gas chromatography/mass
      spectrometry. By the latter method, the PGE(2) content was three-fold higher in
      enterotoxin-activated, compared to basal, cultures at 48 h. Aspirin effectively
      suppressed increases in both iPG and PGE(2). In spleen cell cultures prepared
      from mice previously inoculated with an attenuated strain of yellow fever virus
      in vivo and then incubated with this virus in vitro, iPG levels increased twofold
      over basal at 48 h. By contrast, iPG content of spleen cell cultures prepared
      from saline-inoculated mice was not appreciably altered by exposure to the virus
      in vitro. The enhancement of iPG release from cultured spleen cells by mitogens
      did not correlate with an ability of these agents to increase cellular cyclic AMP
      (cAMP) levels. Moreover, epinephrine and cholera toxin markedly increased spleen
      cell cAMP content but had no demonstrable effect on basal iPG levels, suggesting
      iPG release from these cells was not mediated by cAMP. Incubation with mitogens
      also enhanced the iPG content of 72-cultures of human peripheral leukocytes and
      of human lymphocytes isolated by nylon chromatography. However, the iPG of
      cultures of human lymphocytes purified by glass bead chromatography and of mouse
      thymocytes was not appreciably altered when these cells were cultured with
      mitogens, even though DNA synthesis in both instances was markedly increased.
      Accordingly, iPG release was not an invariable concomitant of increased DNA
      synthesis in lymphoid cell cultures. In summary, the results demonstrate that
      mitogen and antigen stimulation of leukocytes in culture may be accompanied by
      enhanced release of PGE. The mechanisms mediating this phenomenon and its
      biologic significance remain to be delineated, but participation of PGE in
      immunologically induced inflammatory responses seems possible.

PMID- 4367891
TI  - The hypercalciurias. Causes, parathyroid functions, and diagnostic criteria.
AB  - The causes for the hypercalciuria and diagnostic criteria for the various forms
      of hypercalciuria were sought in 56 patients with hypercalcemia or
      nephrolithiasis (Ca stones), by a careful assessment of parathyroid function and
      calcium metabolism. A study protocol for the evaluation of hypercalciuria, based
      on a constant liquid synthetic diet, was developed. In 26 cases of primary
      hyperparathyroidism, characteristic features were: hypercalcemia, high urinary
      cyclic AMP (cAMP, 8.58+/-3.63 SD mumol/g creatinine; normal, 4.02+/-0.70 mumol/g
      creatinine), high immunoreactive serum parathyroid hormone (PTH), hypercalciuria,
      the urinary Ca exceeding absorbed Ca from intestinal tract (Ca(A)), high fasting
      urinary Ca (0.2 mg/mg creatinine or greater), and low bone density by (125)I
      photon absorption. The results suggest that hypercalciuria is partly secondary to
      an excessive skeletal resorption (resorptive hypercalciuria). The 22 cases with
      renal stones had normocalcemia, hypercalciuria, intestinal hyperabsorption of
      calcium, normal or low serum PTH and urinary cAMP, normal fasting urinary Ca, and
      normal bone density. Since their Ca(A) exceeded urinary Ca, the hypercalciuria
      probably resulted from an intestinal hyperabsorption of Ca (absorptive
      hypercalciuria). The primacy of intestinal Ca hyperabsorption was confirmed by
      responses to Ca load and deprivation under a metabolic dietary regimen. During a
      Ca load of 1,700 mg/day, there was an exaggerated increase in the renal excretion
      of Ca and a suppression of cAMP excretion. The urinary Ca of 453+/-154 SD mg/day
      was significantly higher than the control group's 211+/-42 mg/day. The urinary
      cAMP of 2.26+/-0.56 mumol/g creatinine was significantly lower than in the
      control group. In contrast, when the intestinal absorption of calcium was limited
      by cellulose phosphate, the hypercalciuria was corrected and the suppressed renal
      excretion of cAMP returned towards normal. Two cases with renal stones had
      normocalcemia, hypercalciuria, and high urinary cAMP or serum PTH. Since Ca(A)
      was less than urinary Ca, the hypercalciuria may have been secondary to an
      impaired renal tubular reabsorption of Ca (renal hypercalciuria). Six cases with
      renal stones had normal values of serum Ca, urinary Ca, urinary cAMP, and serum
      PTH (normocalciuric nephrolithiasis). Their Ca(A) exceeded urinary Ca, and
      fasting urinary Ca and bone density were normal. The results support the proposed
      mechanisms for the hypercalciuria and provide reliable diagnostic criteria for
      the various forms of hypercalciuria.

PMID- 4367892
TI  - Studies on locust neuromuscular physiology in relation to glutamic acid.

PMID- 4367893
TI  - L-glutamate in arthropod blood plasma: physiological implications.

PMID- 4367894
TI  - Saturday night retinopathy.

PMID- 4367895
TI  - Paradoxical effects of d-amphetamine on behavioral thermoregulation: possible
      mediation by brain dopamine.

PMID- 4367896
TI  - Effects of intracellularly applied cyclic 3',5'-adenosine monophosphate and
      dibutyryl cyclic 3',5'-adenosine monophosphate on the electrical activity of
      sinoatrial nodal cells of the rabbit.

PMID- 4367898
TI  - Inhibition of angiotensin-induced adrenal catecholamine release by 8-substituted
      analogs of angiotensin II.

PMID- 4367897
TI  - Influence of various substances which induce and inhibit aggregation on the
      uptake of deoxyglucose by human blood platelets.

PMID- 4367899
TI  - Reliability of the RNA-DNA filter hybridization for the detection of oncornavirus
      specific DNA sequences.
AB  - Denatured DNA from leukemic myeloblasts or uninfected chicken embryos,
      immobilized on nitrocellulose filters, was hybridized to a vast excess of
      [(3)H]70S RNA from purified avian myeloblastosis virus. The viral RNA was eluted
      from the RNA-DNA hybrids, purified, and then rehybridized in solution to an
      excess of either leukemic or normal chicken embryonic DNA. This study revealed
      that all the slow and the fast hybridizing viral RNA sequences detectable by
      liquid hybridization in DNA excess had hybridized to the filter bound DNA. Both
      techniques also gave similar values for the number of 28S ribosomal RNA genes
      contained in a chicken cell genome: 210 by the liquid hybridization procedure and
      218 by the filter hybridization technique. Therefore, filter hybridization can
      accurately detect DNA sequences present in relatively few numbers in the genome
      of higher organisms.

PMID- 4367900
TI  - Selection of revertants of Kirsten sarcoma virus transformed nonproducer BALB-3T3
      cells.
AB  - Revertants of Kirsten sarcoma virus transformed nonproducer BALB/3T3 cells (KA31
      cells) were isolated after exposing the transformed cells to 5-fluorodeoxyuridine
      at high cell density, or when suspended in methylcellulose. Revertants were also
      isolated by treating KA31 cells with the lectin, concanavalin A, which is
      manyfold more toxic to transformed cells than for normal cells. The revertants
      resemble BALB/3T3 cells in their morphology and growth characteristics in that
      they have a low saturation density, fail to grow in 1% calf serum or when
      suspended in methylcellulose, and cease to synthesize DNA after reaching their
      saturation density. Infection by murine leukemia virus rescues Kirsten sarcoma
      virus from only the concanavalin-A-selected variants, though all the revertants
      are susceptible to infection by leukemia virus. The concanavalin A revertants
      also become transformed after infection with murine leukemia virus. All the
      revertants can be transformed by Kirsten sarcoma virus but not by simian virus
      40.

PMID- 4367901
TI  - Characterization of late polyoma mRNA.
AB  - Polyoma-infected mouse kidney cell cultures were labeled with [(3)H]uridine for 3
      h late in the lytic cycle (26 to 29 h after infection) and RNA was extracted from
      cytoplasm and nuclei and from isolated polyribosomes. Sedimentation velocity
      analysis in sucrose gradients showed that polyoma-specific "giant" and 26S RNAs
      are present exclusively in the nucleus. RNA associated with cytoplasmic
      polyribosomes was analyzed by sedimentation in aqueous sucrose density gradients
      and dimethylsulfoxide sucrose gradients, as well as by polyacrylamide gel
      electrophoresis. Polyoma-specific RNA in polyribosomes consists of at least two
      classes, with sedimentation coefficients of 16 (major fraction) and 19S (minor
      fraction) in aqueous sucrose gradients and 15 and 17S, respectively, in
      dimethylsulfoxide gradients. Estimates based on dimethylsulfoxide gradient and
      analysis suggest a molecular weight of approximately 500,000 for 16S RNA and
      700,000 for 19S RNA. These polyoma RNAs seem to undergo reversible conformational
      changes under the different conditions of analysis. We cannot exclude the
      possibility that they contain more than one molecular species.

PMID- 4367902
TI  - Cleavage of mengovirus polyproteins in vivo.
AB  - The synthesis of mengovirus-specific proteins in vivo was studied by labeling the
      viral proteins with radioactive amino acids under conditions in which host
      protein synthesis was almost completely inhibited. Pulse-chase experiments
      enabled the kinetic analysis of the cleavages of certain viral protein precursors
      and the formation of others. The pattern of cleavages of mengovirus precursor
      polypeptides is similar to that of encephalomyocarditis virus. The major
      difference between the two viruses seems to be in the molar concentration in
      which the various primary products are produced. The molar ratio of the A
      protein, which is the precursor of the capsid proteins, to that of the primary
      products F and C, is approximately 1.5 to 2.0: 1: 1. Possible explanations for
      the unequal appearance of the structural and nonstructural proteins are
      discussed.

PMID- 4367903
TI  - Sialoglycoprotein of vesicular stomatitis virus: role of the neuraminic acid in
      infection.
AB  - Neuraminidase free of proteolytic activity substantially reduced the infectivity
      of vesicular stomatitis (VS) virus but less effectively than trypsin. The only
      sugar residue hydrolyzed by neuraminidase was N-acetyl neuraminic acid,
      approximately 89% of which was liberated from virion glycoprotein and the rest
      from virion glycolipid. Desialylation of virion glycoprotein but not of
      glycolipid resulted in progressive loss of infectivity. Sialyl transferase
      prepared and partially purified from BHK-21 cells catalyzed resialylation by CMP
      [(14)C]sialic acid of the glycoprotein of neuraminidase-treated VS virions and
      supersialylation of unhydrolyzed VS viral glycoprotein. Resialylation of
      desialylated VS virions resulted in substantial (26-fold) restoration of their
      infectivity. We conclude that terminal neuraminic acids of VS viral
      sialoglycoprotein play an important role in initiation of infection with this
      virus.

PMID- 4367904
TI  - Characterization of the large picornaviral polypeptides produced in the presence
      of zinc ion.
AB  - Zinc ion inhibits the posttranslational cleavages of human rhinovirus-1A,
      encephalomyocarditis virus, and poliovirus polypeptides. Each virus displayed a
      different susceptibility to zinc. However, in each case the cleavages of the
      capsid precursor and the cleavages analogous to the C --> D --> E conversion in
      encephalomyocarditis virus were most sensitive to zinc. Higher concentrations of
      zinc resulted in the buildup of even larger precursor polypeptides of a size
      between 106,000 and 214,000 daltons. The sizes of these polypeptides and the
      relative position of their gene loci on the viral RNA were determined. These data
      were used to place these polypeptides in the over-all scheme of viral protein
      processing.

PMID- 4367905
TI  - Transcriptional regulation of T4 bacteriophage-specific enzymes synthesized in
      vitro.
AB  - In contrast to dihydrofolate reductase and four other phage-specific enzymes, the
      initiation of deoxynucleotide kinase is essentially prevented if rifampin is
      added to a culture of Escherichia coli B cells within 1.5 min after infection
      with T4. Deoxynucleotide kinase thus belongs to a group of so-called delayed
      early enzymes that is not initiated from an immediate-early promoter site. We
      prepared crude extracts from infected cells in a manner designed to maintain the
      integrity of the complexes of native, endogenous T4 DNA with bacterial structural
      and enzymatic units concerned with RNA synthesis. The initiation of the synthesis
      of the mRNA for dihydrofolate reductase, an example of an immediate-early enzyme,
      and deoxynucleotide kinase, a special type of delayed-early enzyme, was studied
      with these extracts prepared from cells infected in the absence or presence of
      chloramphenicol. Initiation of transcription of the dihydrofolate reductase gene
      is immediate when programmed by extracts made either from cells treated with
      chloramphenicol prior to infection (CM extracts) or from cells 3 min into the
      normal infection cycle (3-min extracts). However, initiation of transcription of
      the deoxynucleotide kinase gene programmed by CM extracts is delayed 2 min
      relative to the immediate initiation of transcription of the deoxynucleotide
      kinase gene programmed by 3-min extracts. These experiments duplicated in vitro
      effects of the antibiotics on the synthesis of phage-specific mRNA previously
      noted only in vivo.

PMID- 4367906
TI  - Rhabdovirus replication in enucleated host cells.
AB  - Infection of enucleated TC-7 monkey cells with rabies virus resulted in the
      synthesis of virus-directed RNA and the production of rabies antigens but not of
      infectious virus. The yield of infectious vesicular stomatitis virus from
      enucleated TC-7 cells, on the other hand, was almost as high as that from intact
      cells. Inhibition of the mitochondrial functions of enucleated cells by treatment
      with ethidium bromide did not influence the development of rabies antigens or the
      production of infectious vesicular stomatitis virus.

PMID- 4367908
TI  - [Problems of organ, specifically kidney transplantation].

PMID- 4367907
TI  - Growth in agarose of human cells infected with cytomegalovirus.
AB  - After infection by human cytomegalovirus (CMV), human diploid fibroblasts could
      grow in agarose medium for several generations. Clones of infected cells grew for
      weeks, although in every case they ultimately underwent lysis owing to the
      cytopathic effect of the virus. Virus was inoculated at high dilution and after
      UV irradiation in an effort to derive cells infected with noninfectious defective
      particles still capable of inducing cell stimulation. Dilute or irradiated virus
      occasionally yielded large colonies of replicating cells, although permanent
      transformation was not observed. One clone derived from UV-CMV-infected cells was
      passaged four times before undergoing lysis. During these passages the cells
      exhibited alterations in morphology and orientation.

PMID- 4367909
TI  - [Surgery in old age].

PMID- 4367911
TI  - [Burns].

PMID- 4367910
TI  - [Lumbar disk disorders].

PMID- 4367912
TI  - [Aids in modern surgery].

PMID- 4367913
TI  - [Anesthesia and intensive care. VII. Cardiopulmonary resuscitation without
      equipment].

PMID- 4367915
TI  - [Reincorporation of registered nurses previously tied down through marriage or
      housekeeping duties].

PMID- 4367914
TI  - [Emotional dimensions of cognitive group learning].

PMID- 4367916
TI  - Improving emergency-room patient follow-up in a metropolitan teaching hospital.
      Effect of a follow-up check.

PMID- 4367917
TI  - The renin-angiotensin system (first of two parts).

PMID- 4367918
TI  - A comparative study of two structurally related analogs of Asp1-Ile5-angiotensin
      II.

PMID- 4367919
TI  - The preparation of brush border membranes from rat kidney using an aqueous two
      phase polymer system.

PMID- 4367920
TI  - Relative contributions of Ca2+ influx and cellular Ca2+ release during drug
      induced activation of the rabbit aorta.

PMID- 4367921
TI  - [Surface structure of cancer cell with special reference of the cell coat in
      ascites hepatomas (author's transl)].

PMID- 4367922
TI  - Platelet adenylate cyclase responses in depression: implications for a receptor
      defect.

PMID- 4367923
TI  - [Value of arthroscopy in isolated monoarthritis of the knee].

PMID- 4367924
TI  - [Functional tolerance and clinical course of idiopathic femur head necrosis.
      Attempt of prognosis and therapeutic orientation].

PMID- 4367925
TI  - [Physiopathology of osteoporosis in the young adult].

PMID- 4367926
TI  - [Myeloma, melphalan and acute myelo-monocytic leukemia. Apropos of a case].

PMID- 4367927
TI  - [Surgical treatment of gonarthrosis with axial deviation].

PMID- 4367928
TI  - [Bacterial endocarditis and Libman-Sacks syndrome].

PMID- 4367929
TI  - [Isotopic splenoportography. Morphologic and kinetic results].

PMID- 4367930
TI  - [Lateral left artery, instead of marginal left coronary artery].

PMID- 4367931
TI  - [Etiology of postoperative stenosing esophagitis].

PMID- 4367932
TI  - [Type II glycogenosis].

PMID- 4367933
TI  - [Spontaneous hepatoma of the liver during pregnancy].

PMID- 4367934
TI  - [Lithium poisoning].

PMID- 4367935
TI  - [Editoial: Apparently contradictory data concerning breast cancer].

PMID- 4367936
TI  - [Lesional pulmonary edema during peritonitis].

PMID- 4367937
TI  - [Bilateral hypoplasia of the internal carotid arteries. Apropos of an anatomo
      clinical case].

PMID- 4367938
TI  - [A non-aggressive exploration in vertebro-basilar circulatory insufficiency:
      rheography with dynamic tests].

PMID- 4367939
TI  - [Creeping disease, cutaneous myasis. A new holiday disease].

PMID- 4367940
TI  - [Congenital anal tumor, revealing a botryoid sarcoma].

PMID- 4367942
TI  - [ESR investigations on the photochemistry of acridine orange (author's transl)].

PMID- 4367941
TI  - [Resin linked derivatives of serotonin and affinity chromatography of proteins
      isolated from synaptic membranes (author's transl)].

PMID- 4367943
TI  - [Effect of neonatal thymectomy on viral leukemogenesis in the mouse].

PMID- 4367944
TI  - Serum concentrations of beta-melanocyte-stimulating hormone in human pregnancy.

PMID- 4367946
TI  - Acute endogenous panophthalmitis caused by Clostridium perfringens.

PMID- 4367945
TI  - Study of serum lipid and blood fibrinolytic activity in cases of cerebral venous
      venous sinus thrombosis during the puerperium.

PMID- 4367947
TI  - [Electron microscopic observations on parasites of scenedesmus mass cultures. 4.
      Bacteria (author's transl)].

PMID- 4367949
TI  - Experimental vitreous surgery in monkeys. IX. Pars plana approach in open-sky
      technique.

PMID- 4367948
TI  - Cell wall formation in zoospores of Allomyces arbuscula. I. Fine structural
      observations on encysting haploid zoospores.

PMID- 4367950
TI  - Cornea and sclera.

PMID- 4367951
TI  - The concept of social dominance.

PMID- 4367952
TI  - Molecular modifications of anti-aldosterone compounds: effects on affinity of
      spirolactones for renal aldosterone receptors.

PMID- 4367953
TI  - Effects of SC-26096(2-methyl-3-oxo-2azabicyclo(2.2.2.)octan-6-exo-yl 5-(4
      biphenylyl)-3-methyl valerate), a new hypolipidemic agent, on mitochondrial
      respiration and oxidative phosphorylation.

PMID- 4367954
TI  - Effects of opioid narcotic drugs on energy reserves of skeletal muscle. II.
      Further studies of the glycogenolytic action of methadone.

PMID- 4367957
TI  - Deoxythymidine triphosphate-deoxyuridine triphosphate nucleotidohydrolase induced
      by Bacillus subtilis bacteriophage phie.

PMID- 4367955
TI  - Further studies on the inhibition of drug metabolism by pregnanolone and related
      steroids.

PMID- 4367956
TI  - A new phosphodiesterase inhibitor in human lymphocytes: N-methyl-isatin-beta
      thiosemicarbazone.

PMID- 4367958
TI  - The triplet state of reaction center bacteriochlorophyll: determination of a
      relative quantum yeild.

PMID- 4367959
TI  - Biochemical and biophysical studies on cytochrome C oxidase. XIV. The reaction
      with cytochrome as studied by pulse radiolysis.

PMID- 4367960
TI  - Biochemical and biophysical studies on cytochrome oxidase. XV. Reaction with
      fluoride.

PMID- 4367961
TI  - Properties of the cytochrome a-like material developed in the photosynthetic
      bacterium Rhodopseudomonas spheroides when grown aerobically.

PMID- 4367963
TI  - Light-induced absorbance changes in chloroplasts mediated by photosystem I and
      photosystem II at low temperature.

PMID- 4367962
TI  - Characterization of a mutant of Schizosaccharomyces pombe lacking cytochrome b
      566.

PMID- 4367964
TI  - Oxidation of reduced nicotinamide-adenine dinucleotide by the malate-aspartate
      shuttle in Ehrlich ascites tumour cells.

PMID- 4367966
TI  - Metabolism of prostaglandin F2alpha in the rat.

PMID- 4367965
TI  - The distribution of molecular species of monoglycosylceramides (cerebrosides) in
      different parts of bovine digestive tract.

PMID- 4367967
TI  - Microbiological transformation of prostaglandins. II. Stereospecific reduction of
      A (plus or minus)-delta 8(12)-15-dehydroprostaglandin.

PMID- 4367968
TI  - Mechanism of biohydrogenation of cholesterol to coprostanol by Eubacterium ATCC
      21408.

PMID- 4367969
TI  - The acute action of adrenocorticotropic hormone on adrenal steroidogenesis.

PMID- 4367970
TI  - On the solubility, stability and partial purification of CDPdiacyl-sn-glycerol:
      inositol transferase from rat brain.

PMID- 4367971
TI  - Affinity chromatography of 3-oxosteroid delta4--delta5-isomerase of Pseudomonas
      testosteroni.

PMID- 4367972
TI  - Biochemical changes in Bifidobacterium bifidum var. Pennsylvanicus after cell
      wall inhibition. VII. Structure of the phosphogalactolipids.

PMID- 4367973
TI  - Sulfatides of hog gastric mucosa.

PMID- 4367974
TI  - Microsomal synthesis of the ether analogs of triacylglycerols. Acyl
      CoA:alkylacylglycerol and acyl CoA:alk-i-enylacylglycerol acyltransferases in
      tumors and liver.

PMID- 4367975
TI  - The effect of premixing on the oxidation of ethanol by liver alcohol
      dehydrogenase.

PMID- 4367976
TI  - The inhibition of malate dehydrogenase by chlorammine-platinum complexes.

PMID- 4367978
TI  - Studies on glycogen synthase D phosphatase of rat liver--multiple nature.

PMID- 4367977
TI  - Lipoamide dehydrogenase of the phytopathogenic fungi Pythium ultimum and
      Phytophthora erythroseptica. Differences in conformation and kinetics.

PMID- 4367979
TI  - Competition of inorganic pyrophosphate and a phosphomonoester as substrates for
      human placental alkaline orthophosphatase.

PMID- 4367980
TI  - Solid-phase radioimmunoassay of rat skin collagenase. Comparative studies and in
      vivo measurement of the enzyme.

PMID- 4367981
TI  - Separation of multiple dihydrotestosterone receptors in rat ventral prostate by a
      novel micromethod of electrofocusing. Blocking action of cyproterone acetate and
      uptake by nuclear chromatin.

PMID- 4367983
TI  - Electron paramagnetic resonance studies on the copper(II) substituted alkaline
      phosphatase from Escherichia coli.

PMID- 4367982
TI  - The quaternary structure of lactate dehydrogenase. II. The mechanisms, kinetics
      and thermodynamics of dissociation, denaturation and hybridization in ethylene
      glycol.

PMID- 4367984
TI  - Two copper-containing proteins from cucumber (Cucumis sativus).

PMID- 4367985
TI  - Histone and casein kinases of lactating bovine mammary gland.

PMID- 4367986
TI  - Protein disposition in biological membranes.

PMID- 4367987
TI  - The distribution of noradrenergic nerves and small, intensely fluorescent (SIF)
      cells in the cat urinary bladder. A light and electron microscope study.

PMID- 4367990
TI  - The role of the nervous system in regeneration, growth and cell differentiation
      in Hydra. II. Ultrastructural study of nerve cell elements during hypostomal
      regeneration.

PMID- 4367988
TI  - Ultrastructural study of pigment cells of human red hair.

PMID- 4367989
TI  - Ultrastructure of rat pituitary gonadotrophs following incubations of the gland
      with synthetic LH-RH.

PMID- 4367991
TI  - Electron microscopical and cytochemical study of vitelline cells in the fresh
      water triclad Dugesia lugubris s. 1. I. Origin and morphogenesis of cocoon-shell
      globules.

PMID- 4367992
TI  - In vitro maturation of Arbacia punctulata oocytes and initiation of heavy body
      formation. An ultrastructural study.

PMID- 4367993
TI  - Electrophoretic patterns of blood serum proteins of the cyprinid fish, Leuciscus
      leuciscus (L.).

PMID- 4367994
TI  - Organophosphate splitting serum enzymes in different mammals.

PMID- 4367995
TI  - Inhibition of the angiotensin I converting enzyme of the lung by a peptide
      fragment of bradykinin.

PMID- 4367996
TI  - The effect of hydrocortisone on tension and cyclic AMP metabolism in tracheal
      smooth muscle.

PMID- 4367997
TI  - Paracrystalline inclusions in mitochondria of frog oocytes.

PMID- 4367998
TI  - Stimulation of cell aggregation by theophylline in the asexual reproduction of
      fresh-water sponges (Ephydatia fluviatilis).

PMID- 4367999
TI  - Epstein-Barr virus-binding receptor on the surface of chronic lymphocytic
      leukaemic lymphocytes.

PMID- 4368000
TI  - Cyclic guanosine 3',5'-monophosphate and gallbladder contraction.

PMID- 4368001
TI  - Inherited hyperammonemic syndromes.

PMID- 4368002
TI  - Cross-reactions between human and animal plasma proteins. VI. An assay method for
      ape and monkey plasma proteins using antihuman antisera.

PMID- 4368003
TI  - Metastasis of mammary carcinoma to the mandibular condyle.

PMID- 4368004
TI  - Spontaneous conductance changes, multilevel conductance states and negative
      differential resistance in oxidized cholesterol black lipid membranes.

PMID- 4368005
TI  - Localization of a calcium-stimulated ATPase in the basal-lateral plasma membranes
      of the proximal tubule of rat kidney cortex.

PMID- 4368006
TI  - Polar lipid composition of the leaves and seeds from the tea plant (Camellia
      sinensis L).

PMID- 4368007
TI  - [Comparison of the activities of various enzymes in ureteral urine and renal
      venous and arterial blood in 41 patients with arterial hypertension and renal
      artery abnormality].

PMID- 4368008
TI  - To spritz or not to spritz: the doubtful value of aimless iontophoresis.

PMID- 4368011
TI  - Renal effects of cyclic AMP in normal and congenital diabetes insipidus rats.

PMID- 4368009
TI  - The role of the first component of the bovine complement system in the haemolytic
      activity of a bovine derived lytic intermediate.

PMID- 4368010
TI  - A 7S DNA polymerase in the cytoplasmic fraction from higher plant.

PMID- 4368012
TI  - Changes in electrolyte excretion following intraperitoneal injection of dibutyryl
      cyclic AMP in the brattleboro rat.

PMID- 4368013
TI  - Virus-associated enzymes.

PMID- 4368015
TI  - [Prolonged ischemic tolerance time of the human liver with successful grafting
      (author's transl)].

PMID- 4368014
TI  - Kinetic and metabolic studies of Prostaglandin F2-alpha administered intra
      amniotically for induction of abortion.

PMID- 4368016
TI  - [Hepatogenous (secondary) aldosteronism (author's transl)].

PMID- 4368017
TI  - Decreased adrenal sensitivity to ACTH in the vasopressin-deficient (Brattleboro)
      rat.

PMID- 4368018
TI  - Differential localization of the influence of lysine vasopressin and of ACTH 4-10
      on avoidance behavior: a study in rats bearing lesions in the parafascicular
      nuclei.

PMID- 4368020
TI  - Brain monoamines and endocrine function.

PMID- 4368019
TI  - Hypothalamic control of aldosterone production in sodium-deficient rats.

PMID- 4368021
TI  - Neuroendocrine transduction.

PMID- 4368022
TI  - Possible function of monoamines as neurotransmitters.

PMID- 4368023
TI  - Possible sites of action of monoamines in hypothalamohypophyseal function.

PMID- 4368024
TI  - Neuroendocrine transducer input-output relations.

PMID- 4368025
TI  - Monoamines and control of glucocorticoid secretion from the adrenal cortex.

PMID- 4368026
TI  - Gonad function and tuberoinfundibular dopamine.

PMID- 4368027
TI  - Lesion effects on hypothalamohypophyseal function.

PMID- 4368029
TI  - A special baby visitor.

PMID- 4368028
TI  - Brain monoamines and endocrine function. Conclusions.

PMID- 4368030
TI  - [Autoradiographic studies on 99mTc distribution in the mouse].

PMID- 4368032
TI  - Permeability and other properties of the outer mitochondrial membrane.

PMID- 4368031
TI  - Antiviral activities of silver sulfadiazine in ocular infection.

PMID- 4368033
TI  - [Animal experimental studies on manganese poisoning and on the effect of thiamine
      on chronic manganese exposure].

PMID- 4368034
TI  - Permeability of capillaries to different tracers and uptake of horseradish
      peroxidase by the secretory cells in rat anterior pituitary gland.

PMID- 4368035
TI  - 'Stress' hormones and lipid metabolism.

PMID- 4368036
TI  - "Cri du chat" syndrome with maternal insertional translocation.

PMID- 4368037
TI  - [A case of amyotrophic lateral sclerosis syndrome with positive viral tests of
      the cerebrospinal fluid].

PMID- 4368038
TI  - [A case of giant cytosarcoma phyllodes].

PMID- 4368039
TI  - [A case of lung asbestosis and metastatic cancer--interrelation or solely
      concomittance? (author's transl)].

PMID- 4368040
TI  - [A comparison of ultra sound and scanning for placental localisation (author's
      transl)].

PMID- 4368041
TI  - [A new case of myoid tumor of the stomach].

PMID- 4368042
TI  - [A rare cholesteatoma following otobasal fracture].

PMID- 4368044
TI  - [Abnormalities or renal function related to body position, particularly with
      mobile kidneys. Demonstration by means of quantitative sequential seintigraphy
      (author's transl)].

PMID- 4368043
TI  - [A.C.T.H. treatment and its effect on serum cortisol in asthmatic adults].

PMID- 4368045
TI  - [Acquired primary sideroblastic anemia. Apropos of 16 cases].

PMID- 4368046
TI  - [Actinomycosis of the cervical lymph nodes, the epididymis and the testis].

PMID- 4368048
TI  - [Actual therapy and prognosis of malignant tumors in childhood (author's
      transl)].

PMID- 4368047
TI  - [Action of distamycin A and its derivatives on the Moloney murine sarcoma virus
      in vitro and in vivo].

PMID- 4368049
TI  - [Acute mechanism of kidney failure due to mercury chloride poisoning in the rat].

PMID- 4368050
TI  - [Adenocarcinoma of the corpus uteri associated with carcinoid tumor of Meckel's
      diverticulums].

PMID- 4368051
TI  - [Amblyopia as a complication of cerebral angiography (author's transl)].

PMID- 4368052
TI  - [Ampicillin, pivampicillin and amoxycillin. Comparative studies on serum
      concentrations and urinary excretion after oral administration to fasting
      subjects].

PMID- 4368053
TI  - [Angiocinematographic evaluation of tortuosity, coiling and kinking of the
      cervical portion of the internal carotid artery (author's transl)].

PMID- 4368055
TI  - [Antiviral activity of benzimidazole derivatives. IV. Bisbenzimidazole
      derivatives. (2) (author's transl)].

PMID- 4368054
TI  - [Antibody level in aqueous humor and serum in cytomegalic inclusion disease].

PMID- 4368056
TI  - [Arterial pharmaco-portography for portal hypertension (author's transl)].

PMID- 4368057
TI  - [Arteriography in adrenal tumours in childhood (author's transl)].

PMID- 4368058
TI  - [Aspiration cytology in the diagnosis of diseases of the breast (author's
      transl)].

PMID- 4368059
TI  - [Assessment of malignancy of stomach neoplasms according to natural beta
      activity].

PMID- 4368060
TI  - [Association of Herpes simplex virus with human tumors].

PMID- 4368061
TI  - [Australia antigen in chronic liver diseases (author's transl)].

PMID- 4368062
TI  - [ACTH secretion in vitro from dispersed rat pars intermedia cells].

PMID- 4368063
TI  - [Basilar impression and Paget's bone disease, in 2 patients with cerebellar
      tonsil herniation].

PMID- 4368064
TI  - [Bibliographic study of cases of double cancer in Japan in the past 10 years:
      with special reference to our experiences with 7 cases].

PMID- 4368065
TI  - [Biochemical and histochemical studies on the existence of glucose-6-phosphatase
      in the normal human placenta].

PMID- 4368066
TI  - [Biochemical reactions of cyanic acid as the basis for therapy of cyanic acid
      poisoning].

PMID- 4368067
TI  - [C-type viruses in the culture of lymphocytes of cows with leukemia].

PMID- 4368068
TI  - [Calcifying mucinous adenocarcinoma of the stomach--case report and differential
      diagnosis of calcifying processes in the upper abdomen (author's transl)].

PMID- 4368069
TI  - [Calculus-filled diverticulum of the female urethra].

PMID- 4368070
TI  - [Carcinoma in a congenital bronchial cyst-wall].

PMID- 4368071
TI  - [Cardiovascular effects of glucagon].

PMID- 4368072
TI  - [Characteristics of the pathology of bronchial adenomas and the cancers arising
      from them].

PMID- 4368073
TI  - [Chemical compositions of crystalline inorganic components existing in plant
      tissues (author's transl)].

PMID- 4368074
TI  - [Cholera enterotoxin--its biological activity and mechnism of action].

PMID- 4368076
TI  - [Circadian rhythm of plasma renin activity in man (author's transl)].

PMID- 4368075
TI  - [Cholesterolosis with alpha-lipoprotein deficiency (Tangier disease)].

PMID- 4368077
TI  - [Classification of hyperlipoproteinemias].

PMID- 4368078
TI  - [Clinic and histology in dermatological differential diagnoses (author's
      transl)].

PMID- 4368079
TI  - [Clinical aspects and especially dignity of mucoepidermoid tumors of salivary
      glands].

PMID- 4368080
TI  - [Clinical significance of cyclic adenosine 3', 5'-monophosphate determination in
      chronic kidney failure].

PMID- 4368081
TI  - [Clinical significance of restricted respiratory function in ankylosing
      spondylitis].

PMID- 4368082
TI  - [Clinical study of Baralgine in stomatology].

PMID- 4368083
TI  - [Clinical, hematologic, and biochemical study of a case of kala-azar (visceral
      leishmaniasis) observed in Belgium].

PMID- 4368085
TI  - [Clostridium welchii type A enterotoxin].

PMID- 4368086
TI  - [Collagenase activity in human gingiva with periodontal diseases (author's
      transl)].

PMID- 4368084
TI  - [Clinicopathological conference. XV. A metabolic disease diagnosed from a
      fibroblast culture].

PMID- 4368087
TI  - [Combined preoperative radio- and chemotherapy of nephroblastoma (Wilms' tumor)].

PMID- 4368088
TI  - [Comments on the work by K.P. Schulitz and M.Aalam: "Disorders of skeletal growth
      following radiotherapy, and their treatment" (Z.Orthop.3 (1973) 249-257].

PMID- 4368091
TI  - [Congenital cytomegalic inclusive disease (cytomegaly) (author's transl)].

PMID- 4368089
TI  - [Comparative study of the inhibitory effect on platelet aggregation of various
      anti-inflammatory drugs].

PMID- 4368090
TI  - [Complement, hemostasis and kinins. Their interrelationships and their role in
      inflammation].

PMID- 4368093
TI  - [Contagious kerato-conjunctivitis in the Mainz area (author's transl)].

PMID- 4368092
TI  - [Conjugated estrogens in hemorrhages due to ulcerative colitis].

PMID- 4368094
TI  - [Controlled study of the analgesic action of viminol p-OH bezoate in
      suppositories in post-partum pain].

PMID- 4368095
TI  - [Cortisol production and metabolic clearance rate in primary hypothyroidism].

PMID- 4368096
TI  - [Criteria of hormone dependency of breast cancer].

PMID- 4368097
TI  - [Cultivation of the virus of camels' smallpox in the developing chick embryo].

PMID- 4368098
TI  - [Current concepts on the hypothalamo-hypophyseal axis].

PMID- 4368100
TI  - [Cytomegalovirus infection in pregnancy (author's transl)].

PMID- 4368101
TI  - [Day versus inpatient hospitalization for psychiatric patients?].

PMID- 4368099
TI  - [Current problems in hormone research. 2. The role of receptors in some insulin
      effects at the cellular level].

PMID- 4368102
TI  - [Demonstration of golgian secretion in epiphyseal interstitial cells of Symphodus
      melops].

PMID- 4368103
TI  - [Derivatives of vitamin D3 in human and cow's milk: sulfate esters of
      cholecalciferol and 25-hydroxycholecalciferol].

PMID- 4368104
TI  - [Detection of iron in anuclear erythrocytes of Magelona papillicornis F. Muller
      by cytochemistry and electronic sound microanalysis].

PMID- 4368105
TI  - [Development of growth retardation in children with rheumatoid arthritis and
      still's disease: a clinical investigation (author's transl)].

PMID- 4368106
TI  - [Diagnosis of polio-virus infections].

PMID- 4368107
TI  - [Disorders in the tyrosine metabolism. II. Tyrosinemia - a congenital metabolic
      disorder].

PMID- 4368108
TI  - [Distribution of cholesterol and activity of lecithin-cholesterol-
      acyltransferase (LCAT) in quail, as a function of sex].

PMID- 4368109
TI  - [Dysplasias, osteoarthritis and osteonecrosis of the hip].

PMID- 4368110
TI  - [Effect of a high-sodium diet and DOC on the glucocorticoid function of the rat
      adrenals].

PMID- 4368111
TI  - [Effect of adrenaline and angiotensin on the blood pressure of thyroidectomized
      rats].

PMID- 4368112
TI  - [Effect of antibiotics on phagocytosis and killing of Pseudomonas aeruginosa by
      polymorphonuclear leukocytes. II. Effect of some antibiotics, and interaction
      between carbenicillin and PMN intracellular active material (author's transl)].

PMID- 4368113
TI  - [Effect of multicomponent antiangiotensin preparations on the rate of oxygen
      consumption and heart contractions].

PMID- 4368114
TI  - [Effect of silymarin-sodium on hemolysis of human erythrocytes by saponins,
      lysolecithin, sodium dodecylsulfate, phallolysin and theta-toxin from Clostridium
      Welchi].

PMID- 4368115
TI  - [Effectiveness of postoperative radiation therapy of glioblastoma multiforme in
      relation to dose distribution].

PMID- 4368116
TI  - [Effects of aminoglutethimide on cortisol secretion in Cushing's disease].

PMID- 4368117
TI  - [Effects of polyoma virus injections on leukemogenesis in AkR mice].

PMID- 4368118
TI  - [Effects of splanchnic fibres and mechanoreceptors stimulation on unitary
      activity of the somesthesic cortex].

PMID- 4368119
TI  - [Electron spin resonance method and its use for clinical and research purposes].

PMID- 4368120
TI  - [Embryonic kidney tumours; Ultrastructure of nephroblastoma (author's transl)].

PMID- 4368121
TI  - [Embryonic rhabdomyosarcomas in the form of epibulbar subconjunctival tumors
      (author's transl)].

PMID- 4368122
TI  - [Enchondral dysostosis of knee simulating a chisel fracture of the tibial head].

PMID- 4368123
TI  - [Endocrinological problems in renal tumors].

PMID- 4368124
TI  - [Entry of influenza A-Hong-Kong-1-68 (H3-N2) virus into the bronchial and
      alveolar epitheliums of Balb-c mice. Electron microscopy (author's transl)].

PMID- 4368127
TI  - [Epithelial culture isolated from T 3 mouse mammary adenocarcinoma:
      characteristics during 5 years].

PMID- 4368125
TI  - [Enzyme-histochemical studies of mature human placental villi. II. Zonal
      differences in the syncytotrophoblast (author's transl)].

PMID- 4368128
TI  - [Equine rhinovirus infection].

PMID- 4368129
TI  - [Etiologic study of virus infections of the central nervous system in children].

PMID- 4368126
TI  - [Enzymhistochemical and electronmicroscopical studies of the intestinal mucosa of
      the rat in the circadian rhythm (author's transl)].

PMID- 4368131
TI  - [Etiopathogenesis of arteriosclerosis].

PMID- 4368130
TI  - [Etiology of encephalomyocarditis in rhesus monkeys].

PMID- 4368133
TI  - [Experience in treating bronchial cancer with braking radiation].

PMID- 4368132
TI  - [Evaluation of detailed recognition during renal angiography and scanning during
      dog experiments (author's transl)].

PMID- 4368134
TI  - [Experiences with the cytologic rapid diagnosis in thoracic surgery].

PMID- 4368135
TI  - [Experimental and clinical studies on a new synthetic corticotropin with 18 amino
      acids].

PMID- 4368136
TI  - [Experimental results with aimed synthetized substances for antiviral
      chemotherapy. 3. Indandione derivatives and beta ketosulfones].

PMID- 4368138
TI  - [Extracapillary proliferative glomerulonephritis].

PMID- 4368137
TI  - [Experimental results with purposely synthetized substances for antiviral
      chemotherapy. 2. Additional 2-amino-4-phenylthiazoles, tetrahydrobenzthiazoles, 4
      phenylimidazoles, and 8-hydroxyquinolines].

PMID- 4368139
TI  - [Familial distal tubular acidosis].

PMID- 4368140
TI  - [Familial truncular paralysis. A case with biopsy of a peripheral nerve.
      Histopathological lesions of a very peculiar type].

PMID- 4368141
TI  - [Frequency of abnormal lipid values and of hyperlipoproteinaemia in in-patients
      of a general hospital (author's transl)].

PMID- 4368143
TI  - [Gastro-duodenal band and double pylorus (author's transl)].

PMID- 4368142
TI  - [Functional tumors of the ovary].

PMID- 4368145
TI  - [Glycogen and glucose-6-phosphatase during cancerization of rat liver cells by N
      nitrosomorpholine (author's transl)].

PMID- 4368144
TI  - [Glucose retention and growth rate of tumors (author's transl)].

PMID- 4368146
TI  - [Hepatic disarterialization in the treatment of primary cancer of the liver].

PMID- 4368147
TI  - [Hepatitis-B-antigen in cases of viral hepatitis in Munich (author's transl)].

PMID- 4368148
TI  - [Herpes vaccination in the treatment of dendritic keratitis].

PMID- 4368149
TI  - [High affinity of mouse embryo serum for estrogens (author's transl)].

PMID- 4368150
TI  - [Histochemical evaluation of ovarian tumors and indexes of hormonal activity].

PMID- 4368151
TI  - [Hormonal control of lipolysis of isolated fat cells in several domestic and wild
      mammals].

PMID- 4368152
TI  - [Hydrocephalus as a sequel of foetal injury by cytomegalovirus (author's
      transl)].

PMID- 4368153
TI  - [Hyperlipemia and lipoproteinogram].

PMID- 4368154
TI  - [Hypoglycemia].

PMID- 4368155
TI  - [Hypophysiotropic hypothalamic chemical mediation].

PMID- 4368156
TI  - [Immunology of Epstein-Barr virus in lymphoproliferative diseases].

PMID- 4368157
TI  - [In vitro action of dibutyryl-3'-5'-AMPc on thyroid explants of Gobius niger L].

PMID- 4368159
TI  - [In vivo-demonstration of cytoplasmic actomyosin-fibrils (author's transl)].

PMID- 4368160
TI  - [Incorporation of SV40-tumor specific transplantation antigen (SV40-TSTA) in
      vesicular stomatitis virus grown in SV40 transformed hamster cells (author's
      transl)].

PMID- 4368158
TI  - [In vitro induction of the S phase in multipotent stem cells of bone marrow by
      parathyroid hormone].

PMID- 4368161
TI  - [Indirect (arterial) spleno-portography and portography in the diagnosis of pre
      hepatic blocks (author's transl)].

PMID- 4368162
TI  - [Infection by avian myeloblastosis virus, rapidly labeled polysomal heavy RNA
      biosynthesis and cell differentiations].

PMID- 4368163
TI  - [Insulinoma--diagnostic aspects].

PMID- 4368164
TI  - [Insulinopoiesis in various neurologic syndromes. Study using oral glucose load
      and tolbutamide test].

PMID- 4368165
TI  - [Interaction of alkyl sulfite salts of p-dimethylaminobenzaldehyde].

PMID- 4368166
TI  - [Intestinal biopsy in dystrophy and prolonged diarrhea of infants. Its importance
      in the diagnosis and conduct of diet therapy].

PMID- 4368167
TI  - [Isolation of carboxycathepsin (peptidyl dipeptidases 3.4.15.1) from bovine
      kidneys].

PMID- 4368168
TI  - [Isolation of latent herpes viruses in horses].

PMID- 4368169
TI  - [Isolation, purification and differentiation of Clostridium welchii (perfringens)
      from heavily contaminated material].

PMID- 4368170
TI  - [Jubilee of the discovery of anatoxins and current practice of diphtheria and
      tetanus vaccinations].

PMID- 4368171
TI  - [Kaposi's sarcoma: tissue culture studies: viral and immunologic studies].

PMID- 4368172
TI  - [Klebsiella aerogenes infection in turkey chicks and therapeutic attempts using
      polymyxin B].

PMID- 4368173
TI  - [Letter: Serum immunoglobulins in liver tumours].

PMID- 4368174
TI  - [Lipid composition of plasma light-beta-lipoproteins in total body irradiated
      rabbits].

PMID- 4368175
TI  - [Liver in progressive myoclonus epilepsy (Lafora's disease) (author's transl)].

PMID- 4368176
TI  - [Localization of viral antigens of Myxomatosis, by immunoperoxidase].

PMID- 4368178
TI  - [Macular edemas caused by papillary lesions--a macular edema combined with a
      cystic lesion in optic disc (author's transl)].

PMID- 4368179
TI  - [Malignant papillomatosis in a giant breast cyst].

PMID- 4368177
TI  - [Long- and short-term effects of sulpiride on sleep-EEG of man].

PMID- 4368180
TI  - [Medical treatment of malignant bone tumors (carcinolytics, hormonotherapy,
      immunotherapy)].

PMID- 4368181
TI  - [Medullary sponge kidney (author's transl)].

PMID- 4368182
TI  - [Method for calculation of the titer of 3 types of poliovirus present in
      trivalent anti-poliomyelitis vaccine for oral use].

PMID- 4368183
TI  - [Microlymphangiography of the stomach: interpretation of developmental pattern of
      early gastric cancer].

PMID- 4368184
TI  - [Micromethod for determining pyridoxal kinase activity in serum].

PMID- 4368185
TI  - [Mixed tumors of the soft palate].

PMID- 4368187
TI  - [Modification of the method of aggregate hemagglutination for determining the
      alpha-fetoprotein in patient sera].

PMID- 4368186
TI  - [Modification of properties of hydrocarbon-ointments. 7. Effect of suspended
      substances on consistency].

PMID- 4368188
TI  - [Morphology of the postacute visceral ectromelia].

PMID- 4368189
TI  - [Multiple necrosing histiocytomas. A clinical presentation simulating an allergic
      vascularitis].

PMID- 4368190
TI  - [Myocarditis caused by herpes simplex virus].

PMID- 4368191
TI  - [Myoid tumor of the stomach. Apropos of 2 new cases].

PMID- 4368192
TI  - [Nasal ozena within the framework of autoimmune diseases (clinical and
      experimental studies)].

PMID- 4368194
TI  - [Neoplasms of the small intestine].

PMID- 4368195
TI  - [Neuro-radiologic confirmation of tumors of the auditory canal].

PMID- 4368193
TI  - [Necrotic enteritis in broilers. II. Characteristics of the strains of
      Clostridium perfringens isolated].
AB  - A Gram positive bacillus, strictly anaerobic, was isolated from the viscera of
      all diseased birds showing lesions of necrotic enteritis. Its morphology and
      biochemical reactions, the presence of alpha and theta hemolysins and the
      production of a lecithinase-C in vitro, all these characteristics indicated a
      similarity to those belonging to the group of Clostridium perfringens. The two
      hemolysins were neutralized in vitro only by the antitoxin A. Broiler chickens
      injected I.V. with a Viande-Foie (VF) broth culture of Clostridium perfringens
      together with the antitoxin A survived, whereas those receiving antitoxin C died.
      These results seem to indicate that this organism belongs to the type A. This
      bacillus was sensitive to a great variety of antibiotics, except neomycin.

PMID- 4368196
TI  - [Neurologic manifestations of hereditary digestive polyposes].

PMID- 4368197
TI  - [Neurologic manifestations of viral diseases].

PMID- 4368198
TI  - [Neuropathy and lymphoma: a clinical-pathological discussion].

PMID- 4368199
TI  - [New methods in infant-neurology and rehabilitation].

PMID- 4368200
TI  - [Nitrosamines (NA) in the atmospheric air and in the air at the places of
      employment (author's transl)].

PMID- 4368201
TI  - [Ophthalmological diagnosis of cytomegalic retinitis (author's transl)].

PMID- 4368202
TI  - [Ovarian tumors in young women].

PMID- 4368203
TI  - [Palatal cylindroma].

PMID- 4368204
TI  - [Partial neuronal denervation as treatment principle of affective disorders. A
      preliminary report].

PMID- 4368205
TI  - [Pathogenesis of acute kidney failure in shock and renal circulation in man].

PMID- 4368206
TI  - [Pathogenesis of hyperlipoproteinemias].

PMID- 4368207
TI  - [Peripheral neurogenic amyotrophy in the Marinesco-Sjogren syndrome].

PMID- 4368208
TI  - [Peripheral neuropathy due to vincristine. Ultrastructural study of muscle and
      peripheral nerve biopsy].

PMID- 4368209
TI  - [Peripheral neuropathy in malignant dysglobulinemias. Immunopathological
      aspects].

PMID- 4368210
TI  - [Persistence of morphogenetic effect after cessation of general metabolic effect
      of thyroxine in newborn rat].

PMID- 4368211
TI  - [Persistent viral infections of the central nervous system appearing in the
      prenatal or perinatal period].

PMID- 4368212
TI  - [Phagocytosis of lymphocytes. Electron microscopic investigation (author's
      transl)].

PMID- 4368213
TI  - [Pheochromocytoma with an intra-petrous development].

PMID- 4368214
TI  - [Phospholipid metabolism in alveolar macrophages of lungs. (32P)orthophosphate
      incorporation in pulmonary surfactant phospholipids in rat in vivo and in vitro
      (author's transl)].

PMID- 4368215
TI  - [Photo reports: Granuloma faciale eosinophilicum, paravaccinal milkers' nodules,
      primary syphilitic lesion, ulcus phagedaenicum, Albright's hereditary
      osteodystrophy].

PMID- 4368216
TI  - [Physicochemical properties of medicinal agents. 3. Partition coefficients and
      acid dissociation constants of N2-substituted-N1-arylsulfonylurea derivatives
      (author's transl)].

PMID- 4368217
TI  - [Pituitary gland adenomas with galactorrhea].

PMID- 4368218
TI  - [Plasma cell inclusions in acid maltase deficiency (author's transl)].

PMID- 4368219
TI  - [Possibilities of determining fetal age from the morphological development of the
      bones of the base of the skull].

PMID- 4368220
TI  - [Postnatal development and hormonal control (author's transl)].

PMID- 4368221
TI  - [Potassium perchlorate inhibition test in iodine metabolic disorders].

PMID- 4368222
TI  - [Preliminary data on the ultrastructure of the mature ovarian ovum of
      Chaetopterus pergamentaceus C].

PMID- 4368223
TI  - [Presentation of microfilaments in the cytoplasm of Entamoeba histolytica
      (author's transl)].

PMID- 4368224
TI  - [Primary aldosteronism].

PMID- 4368225
TI  - [Primary meningitis due to Cryptococcus neoformans associated with
      polyradiculitis. Cure by amphotericin B].

PMID- 4368226
TI  - [Principles and results of treatment of infantile carcinosis represented by
      osteogenic sarcoma, Wilms' tumor and neuroblastoma (author's transl)].

PMID- 4368227
TI  - [Probable existence of hexosaminidase C locus located on chromosome 7 in man].

PMID- 4368228
TI  - [Proceedings: Analysis of androgens in hirsutic women].

PMID- 4368229
TI  - [Proceedings: Effect of triiodothyronine (T3) and adrenocorticotropin (ACTH) on
      the circulating red cell mass-lean mass ratio of the hypophysectomized rat].

PMID- 4368230
TI  - [Proceedings: Pathogenesis of hypertension--hypotheses and facts].

PMID- 4368231
TI  - [Proceedings: Plasma cortisol and cortisol secretion rates in patients with
      bronchial carcinoma].

PMID- 4368232
TI  - [Prognosis of hypertension disease and of the system renin-angiotension
      aldosteron (author's transl)].

PMID- 4368233
TI  - [Proof of mutagenicity of foreign substances].

PMID- 4368234
TI  - [Properties and evaluation of oleogels. 1. Definition, review, orientation
      studies on consistency and structural stability].

PMID- 4368235
TI  - [Properties and evaluation of oleogels. 2. Studies on autoxydation and
      stabilisation].

PMID- 4368236
TI  - [Properties and kinetic mechanism of D-beta-hydroxybutyrate dehydrogenase from
      rat liver submitochondrial particles. Comparative study of the effects of
      differents thiols].

PMID- 4368237
TI  - [Prophylactic effects of 5,6-trans-25hybroxycholecalciferol on acute oral cadmium
      intoxication (author's transl)].

PMID- 4368238
TI  - [Raman spectroscopy in investigation of protein structure (author's transl)].

PMID- 4368239
TI  - [Rapid semi-purification of rat renal renin by affinity chromatography].

PMID- 4368240
TI  - [Recent advances in platelet research].

PMID- 4368241
TI  - [Recurrent familial neuropathy].

PMID- 4368242
TI  - [Reflex algodystrophy of the legs of vertebro-pelvic origin (apropos of 23
      cases)].

PMID- 4368244
TI  - [Relation of Dematiaceae species and mutants to oxygen content in the air].

PMID- 4368243
TI  - [Regulation of estrogen "receptors" in mammary tumors: action of prolactin in
      vivo].

PMID- 4368245
TI  - [Renal insufficiency and renin-angiotensin-aldosterone].

PMID- 4368246
TI  - [Resistance of chickens of the White Leghorn stock to Rous sarcoma virus].

PMID- 4368248
TI  - [Reversible ectasia of the renal cavity system of traumatic origin].

PMID- 4368247
TI  - [Results of surgical treatment for primary cancer of the liver (author's
      transl)].

PMID- 4368250
TI  - [Scutacaridae of the Lamto savane (Ivory Coast) (Acarina: Tarsonemida). 2.
      Imparipedinae, with description of a new species].

PMID- 4368249
TI  - [Schilder's diffuse sclerosis involving the spinal cord and optic nerve].

PMID- 4368251
TI  - [Semisynthetic penicillins. 13. Comparative studies of antibacterial action in
      vitro of 6-(N,N-1',6'-hexylenformamidino)-penicillanic acid and(D- (D-(minus)
      alpha-aminobenzyl)-penicillanic acid against clinical pathogenic gram negative
      strains].

PMID- 4368252
TI  - [Septicemia due to staphylococcus albus. Report of 14 personal cases].

PMID- 4368253
TI  - [Septum formation in sporogenic and asporogenic Bacillus megaterium cells during
      transition to nitrogen- and carbon starvation].

PMID- 4368254
TI  - [Serum activity of some enzymes in patients with ulcerative colitis].

PMID- 4368255
TI  - [Serum lipoproteins in acute viral hepatitis (author's transl)].

PMID- 4368256
TI  - [Severe infections and septicemia due to group B streptococci in adults. Report
      of 4 cases including 1 case of tricuspid endocarditis complicated by
      glomerulonephritis].

PMID- 4368257
TI  - [Significance of extended laboratory-diagnostic studies on donor blood].

PMID- 4368258
TI  - [Significance of reovirus infections in equine respiratory tract diseases].

PMID- 4368259
TI  - [Sodium dimercaptopropansulfonate (unithiol) in the treatment of stannosis].

PMID- 4368260
TI  - [Somatomedin activity of the serum in the normal child and in hypopituitarism].

PMID- 4368262
TI  - [Sorption conduct of steroids in silicic acid surfaces].

PMID- 4368261
TI  - [Some problems on the microassay of enzyme proteins (author's transl)].

PMID- 4368263
TI  - [Sorption of drugs on surface-treated silicic acids].

PMID- 4368264
TI  - [Sphincter of Oddi].

PMID- 4368265
TI  - [Stimulation by thyrotropin of thyroid gland calcium mobilization].

PMID- 4368266
TI  - [Structure of the antifungal antibiotic MBU-18].

PMID- 4368267
TI  - [Studies on adrenal-cortex function in farm animals using cortisole and
      corticosterone determinations following the principle of concurrent protein
      binding. 3. Studies in birds].

PMID- 4368268
TI  - [Studies on the removal of nonspecific inhibitors and heteroagglutinins in the
      parainfluenza-hemagglutination inhibition test (author's transl)].

PMID- 4368269
TI  - [Study of temperature-induced structural changes in the membranes of thermophilic
      bacteria using a spin probe and light scattering].

PMID- 4368270
TI  - [Study of the correlation between certain liver diseases and a non-constitutional
      precipitating system. Milan antigen?].

PMID- 4368271
TI  - [Study of the hemadsorption plaques formed by 3 strains of parainfluenza virus
      type 3].

PMID- 4368272
TI  - [Study of the intestinal mucosa in dystrophic infants. Histoenzymological
      aspects].

PMID- 4368273
TI  - [Superinfection by Neisseria catarrhalis in Herpesvirus hominis infection
      (author's transl)].

PMID- 4368274
TI  - [Surgical treatment of recurrent misposition of the eyelids with scleras,
      preserved in glycerin].

PMID- 4368275
TI  - [Synthesis of azolidine derivatives with possible hypoglycemic action. IX. 2'
      Arylsulfonyl-3-aryl-(alkyl-) derivatives of 2-iminothiazolidone-4].

PMID- 4368276
TI  - [Synthetic ACTH in the treatment of hyalitis].

PMID- 4368277
TI  - [The action of glucagon on Escherichia coli spheroplasts].

PMID- 4368278
TI  - [The biological activities of cytochrome c hemeoctapeptide (CHP). (2). The
      effects of CHP against the tissue damage caused by dl-isoproterenol-induced
      cardiac infarct-like angina (author's transl)].

PMID- 4368279
TI  - [The correlation between radiographic appearance and contrast excretion during
      infusion urography with dissimilar renal function (author's transl)].

PMID- 4368281
TI  - [The normal angiographic anatomy of the spleen (author's transl)].

PMID- 4368280
TI  - [The development of sleep in newborn rat separated from its mother. Effects of
      alpha-methyl-dopa (author's transl)].

PMID- 4368282
TI  - [The radiological evaluation of splenic size (author's transl)].

PMID- 4368283
TI  - [The radiology of cancellous bone transplants following implantation and during
      healing (author's transl)].

PMID- 4368285
TI  - [The triple diagnosis of benign and malignant tumours of the breast by clinical
      findings, mammography and cytology (author's transl)].

PMID- 4368284
TI  - [The role of adenosine-3',5'-monophosphate in the development of Acanthamoeba
      castellanii (author's transl)].

PMID- 4368286
TI  - [The virulence plasmids of Enterobacteriaceae].

PMID- 4368287
TI  - [Thoracic manifestations of Recklinghausen's neurofibromatosis (1882)].

PMID- 4368288
TI  - [Threatening of the foetus in various, mostly viral infections affecting pregnant
      women (author's transl)].

PMID- 4368289
TI  - [Thyroid pathology of hypothalamic origin].

PMID- 4368290
TI  - [Tissue culture of viruses (author's transl)].

PMID- 4368291
TI  - [Tomography for injuries of the larynx (author's transl)].

PMID- 4368292
TI  - [Total upper lid reconstruction following excision of extensive carcinoma].

PMID- 4368293
TI  - [Trans-tympanic examination of the auditory meatus (author's transl)].

PMID- 4368294
TI  - [Traumatic lesions of the brachial plexus. Surgical treatment, transplantation,
      long term results].

PMID- 4368296
TI  - [Treatment of 44 cases of nasopharyngeal angiofibroma].

PMID- 4368295
TI  - [Treatment of oat cell cancer of the lung].

PMID- 4368297
TI  - [Ultrasonic analysis of cancers of the liver (author's transl)].

PMID- 4368298
TI  - [Ultrastructural changes in the alveolar wall of the remaining lung following
      pulmonectomy in the dog].

PMID- 4368299
TI  - [Ultrastructure of ovarian tumors].

PMID- 4368300
TI  - [Ultrastructure of the septa in the human placenta].

PMID- 4368302
TI  - [Variations of percentage of initial 32P incorporation into fibroblastic
      phosphatidylcholine and phosphatidylethanolamine after viral transformation].

PMID- 4368301
TI  - [Value of telethermography in the study of primary malignant bone tumors].

PMID- 4368303
TI  - [Vascular abnormalities in cerebral tumours. A comparative study of enzyme
      activity and permeability to fluorescent tracers].

PMID- 4368304
TI  - [Vertebral manifestation of fibrous dysplasia (author's transl)].

PMID- 4368305
TI  - [Viewpoints of breast biopsy. An evaluation of cases in the years 1969 to 1972].

PMID- 4368307
TI  - [Virilizing tumors of the ovary].

PMID- 4368306
TI  - [Viral hepatitis in children].

PMID- 4368308
TI  - [Virus diseases of the skin].

PMID- 4368309
TI  - [Wegener's syndrome with renal involvement. Histological, therapeutic and
      immunopathological study].

PMID- 4368310
TI  - [Weight study of the chick embryo and its adrenal glands: normal, decapitated and
      ACTH-treated embryos].

PMID- 4368311
TI  - [WDHA (watery diarrhea, hypokalemia, a chlorhydria) syndrome].

PMID- 4368312
TI  - [3 cases of calculous cholecystitis with retention icterus without lithiasis of
      the common bile duct].

PMID- 4368314
TI  - A catch-up phenomenon in skeletal development of children with Down's syndrome.

PMID- 4368315
TI  - A chickenpox epidemic in a pediatric burn unit.

PMID- 4368313
TI  - A basic approach to the understanding of seizures and the mechanism of action and
      metabolism of anticonvulsants.

PMID- 4368316
TI  - A chromatographic method of assay of colchicine alkaloid.

PMID- 4368319
TI  - A comparison of graduate and recidivist WISC IQ scores in a delinquency treatment
      program for girls.

PMID- 4368318
TI  - A comparative study of viruses associated with acute haemorrhagic conjunctivitis.
AB  - Seven representative isolates from six outbreaks of acute haemorrhagic
      conjunctivitis were shown to have the characteristics of enteroviruses. Two
      viruses differed from the remaining five isolates in producing paralysis in
      suckling mice and being resistant to 2-hydroxybenzyl-benzimidazole. These two
      viruses were also closely related antigenically and distinct from the other five
      viruses which were serologically similar to each other. Neither group of viruses
      was inhibited by antisera to the known enteroviruses and they probably represent
      two new enterovirus types one related to the Coxsackie A viruses and the other to
      the echoviruses.

PMID- 4368317
TI  - A comparative histochemical study of some oxidative and hydrolytic enzymes in the
      kidneys of domestic food animals, laboratory animals and the fowl.

PMID- 4368320
TI  - A comparison of urea and alkali degradation of full and empty bovine enterovirus
      particles.

PMID- 4368322
TI  - A cytomegalovirus vaccine?

PMID- 4368321
TI  - A critical investigation into the antibiotic sterilization of heart valve
      homografts.

PMID- 4368323
TI  - A deletion mutation placing the galactokinase gene of Escherichia coli under
      control of the biotin promoter.
AB  - A deletion has been isolated which fuses galK and presumably galT to the promoter
      and operator of the bioA operon. The deletion has endpoints in bioA and galE, and
      leaves the operator-proximal end of bioA intact and the regulatory sites
      themselves functional. In bacterial strains which carry the deletion, the
      expression of galK is regulated by biotin, although due to the inefficiency of
      the bioA promoter even the fully derepressed level of galactokinase is low.
      Electron micrographic examination of the mutation shows that it is a simple
      deletion, uncomplicated by other chromosomal abnormalities.

PMID- 4368324
TI  - A demonstration of several deoxyribonuclease activities in mammalian cell
      mitochondria.
AB  - Extracts of purified mitochondria from adult rabbit liver and kidney have been
      prepared by lysis with Triton X-100. Such extracts contain deoxyribonuclease
      activity demonstrable at alkaline pH. Studies utilizing the effects of substrate
      variation, differing ionic strength, nucleoside di- and triphosphates, and SH
      group inhibitors reveal the existence of at least five distinguishable
      deoxyribonuclease activities in these extracts. Assay of lysosomal and
      mitochondrial enzyme markers indicates no significant lysosomal contamination of
      the mitochondrial extracts. Further studies also suggest that the alkaline
      deoxyribonuclease activity is specifically located in or in association with
      mitochondria.

PMID- 4368325
TI  - A differential effect of chronically administered guanethidine on sympathetic
      neurotransmission to the dog heart and mesenteric arterial blood vessels.

PMID- 4368327
TI  - A filter assay for the sex steroid binding protein (SBP) of human serum.

PMID- 4368326
TI  - A family study of 50 REM narcoleptics.

PMID- 4368328
TI  - A health and seroepidemiological survey of a community in Barbados.

PMID- 4368329
TI  - A large hepatoma without apparent abnormality on laparotomy.

PMID- 4368330
TI  - A method for the implanation of solid and liquid materials in the marrow cavity
      of the femur of small laboratory animals.

PMID- 4368331
TI  - A modified tendon transference for radial nerve paralysis.

PMID- 4368332
TI  - A modified two-dimensional gel system for the separation and radioautography of
      microgram amounts of ribosomal proteins.

PMID- 4368333
TI  - A molecular theory of lipid-protein interactions in the plasma lipoproteins.

PMID- 4368334
TI  - A new acid hydrolysis method for determining tryptophan in peptides and proteins.

PMID- 4368335
TI  - A new approach to the study of nucleotide sequences in DNA: the analysis of
      termini formed by DNases.

PMID- 4368336
TI  - A new assay of cyclic nucleotide phosphodiesterase; its application to human
      serum.

PMID- 4368337
TI  - A new procedure for the two-dimensional display of the molecular size-electric
      charge characteristics of native proteins in crude mixtures.

PMID- 4368338
TI  - A new purine ring closure and the synthesis of 2-substituted derivatives of
      adenosine cyclic 3',5'-phosphate.

PMID- 4368339
TI  - A nuclear magnetic relaxation study of Co(II) bovine superoxide dismutase.
      Evidence that the Co(II) site is exchange-coupled to the copper and not
      accessible to the solvent.

PMID- 4368340
TI  - A parasitological survey of a village in a mountain district of Papua.

PMID- 4368341
TI  - A possible biological function of the protein kinase associated with vaccinia and
      vesicular stomatitis virions.

PMID- 4368342
TI  - A probable mechanism for apurinic acid inhibition of DNA synthesis.

PMID- 4368343
TI  - A pure sign of lumbrical function.

PMID- 4368344
TI  - A qualification to the use of TEA as a tracer for monosynaptic pathways.

PMID- 4368345
TI  - A quantitative approach to habituation and to evaluation of the effects of noisy
      neural pathways in a crayfish system.

PMID- 4368346
TI  - A radioimmunoassay for serum dehydroepiandrosterone.

PMID- 4368347
TI  - A rapid isolation of phosphoribosyladenosine triphosphate synthetase and
      comparison to native enzyme.

PMID- 4368348
TI  - A re-evaluation of the effects of lesions of the pontine tegmentum and locus
      coeruleus on phenomena of paradoxical sleep in the cat.
AB  - Bilateral lesions placed in the pontiene tegmentum resulted in episodes of
      paradoxical sleep in which the characteristic atonia of that sleep stage was
      absent in six cats. Following each period of synchronized sleep, in which the
      degree of muscle tone of the dorsal cervical muscles gradually diminished, cats
      with such lesions would slowly raise their heads, move their limbs at all joints,
      make several attempts to rise and eventually leap violently. During such episodes
      they were unresponsive to strong lights, touching and mild pinching. Only sound
      would arouse them. This behavior appeared as early as the 2nd postoperative day,
      the 1st day of recording. Such episodes supplanted normal paradoxical sleep with
      atonia and lasted unchanged for as long as 6 months in one cat until it was
      killed while still in good health. Complete recovery of atonia was observed in
      one cat after 3 weeks. Either no recovery or else eventual recovery to
      excessively active periods of paradoxical sleep while remaining recumbent
      characterized the sleep of the other four. The conclusion drawn from these
      experiments and from a review of the literature is that the hypotheses stating
      that the locus coeruleus or other isolated nuclei of the pons are specifically
      concerned with the initiation of paradoxical sleep are not clearly supported by
      available evidence.

PMID- 4368349
TI  - A resolution of conflicting reports concerning the mode of action of fusidic
      acid.

PMID- 4368350
TI  - A retrospective study of lung cancer in Bombay.
AB  - This is a retrospective study of 520 patients with lung cancer, seen at the Tata
      Memorial Hospital between 1963 and 1970. Matched controls were obtained from
      those patients who came to the hospital within the same period and who were
      diagnosed as not having cancer. The patients and controls were matched for age,
      sex and community. As reported in other studies, an association was found between
      smoking habit and lung cancer. The relative risk of all types of smokers to non
      smokers is 2.45, of bidi smokers 2.64 and of cigarette smokers 2.23. There is a
      preponderance of the group of epidermoid carcinomata among smokers as against
      adenocarcinomata. The probable reasons for the reported low incidence of lung
      cancer in this population have been discussed.

PMID- 4368351
TI  - A role of the carbohydrate moiety of glucose oxidase: kinetic evidence for
      protection of the enzyme from thermal inactivation in the presence of sodium
      dodecyl sulfate.

PMID- 4368352
TI  - A semi-automated in vitro assay for CRF: activities of peptides related to
      oxytocin and vasopressin.

PMID- 4368353
TI  - A sensitive method for the detection of corticotrophin releasing factor using a
      perfused pituitary cell column.

PMID- 4368354
TI  - A serologic study on cytomegalovirus infection associated with blood transfusion
      in Japanese.

PMID- 4368355
TI  - A simple modification of the Tudor Thomas eye piece stand.

PMID- 4368356
TI  - A simplified technique for hepatic resection: the crush method.
AB  - A new technique of hepatic lobectomy with combined use of hepatic clamp and liver
      crush clamp is described. It is a simplification of the original finger fracture
      technique by using instruments instead of fingers for hepatic resection. It
      provides the unexperienced with a technique of hepatic resection done in the
      shortest possible time and in an almost bloodless field with safety. Since
      February 1973 the author has performed 5 hepatic resections with this crush
      method for primary liver cell carcinoma. The blood transfusion averaged 200 ml
      and the operation time averaged 1.5 hours. No complication or mortality was
      encountered and the patients were invariably discharged within 14 days after the
      operation.

PMID- 4368357
TI  - A small portable centrifugal fast analyzer system.

PMID- 4368358
TI  - A special program for nurse addicts.

PMID- 4368360
TI  - A thermodynamic approach to the problem of stabilization of globular protein
      structure: a calorimetric study.

PMID- 4368359
TI  - A spectrophotometric assay of beta-lactamase action on penicillins.
AB  - A new method for measuring the enzymic hydrolysis of the beta-lactam ring in
      penicillins is described. The change in extinction in the u.v. region is
      determined. The method is sensitive (50mum-benzylpenicillin can be used) and
      convenient.

PMID- 4368361
TI  - A transmissible antigen detected in two cell lines derived from human tumours.

PMID- 4368362
TI  - Abortive infection and transformation of human embryonic fibroblasts by Molluscum
      contagiosum virus.

PMID- 4368365
TI  - Acidic nuclear protein synthesis in Rous Sarcoma virus infected chick embryo
      fibroblasts.

PMID- 4368364
TI  - Accumulation and metabolism of 3H-epinephrine by the rat heart during variable
      states of adrenocortical function.

PMID- 4368363
TI  - Acceleration of sugar transport in avian erythrocytes by catecholamines.

PMID- 4368366
TI  - Action of 'diamide' on some energy linked processes of rat liver mitochondria.

PMID- 4368367
TI  - Action of cyclic 3',5' adenosine monophosphate on the uterus of the
      ovariectomized rat.

PMID- 4368368
TI  - Activation by reductive cleavage of potentially cytotoxic azo compounds by human
      hepatocellular carcinoma.

PMID- 4368369
TI  - Activation of cholesteryl esterase in bovine adrenal cortex.

PMID- 4368370
TI  - Activation of latent collagenase by microbial plaque.

PMID- 4368371
TI  - Activation of the peripheral lymphocytes in the course of the immune response to
      transplanted SV40-transformed tumour cells in hamsters.

PMID- 4368372
TI  - Activation of transcription at specific promoters by glycerol.

PMID- 4368373
TI  - Adenocarcinoma of the larynx.

PMID- 4368374
TI  - Adenosine 3',5'-cyclic phosphorothioate: synthesis and biological properties.

PMID- 4368375
TI  - Adenovirus polypeptide synthesis in the presence of non-replicating poliovirus.

PMID- 4368376
TI  - Adenyl cyclase and the cyclic AMP responsive systems in the uterus.

PMID- 4368377
TI  - Adenylate cyclase assay with adenylyl imidodiphosphate and product detection by
      competitive protein binding.

PMID- 4368378
TI  - Adrenal steroids in leukemia and lymphoma.

PMID- 4368379
TI  - Adreno-leukodystrophy (sex-linked Schilder disease). Ultrastructural
      demonstration of specific cytoplasmic inclusions in the central nervous system.

PMID- 4368380
TI  - Adrenocortical function following long-term corticosteroid treatment.

PMID- 4368381
TI  - Adrenocortical function in the Burmese.

PMID- 4368383
TI  - Adriamycin in advanced bronchogenic carcinoma.

PMID- 4368384
TI  - Adult lipoid nephrosis: clinicopathological correlations.

PMID- 4368382
TI  - Adrenocorticotrophic and melanocyte-stimulating peptides in the human pituitary.
AB  - The adrenocorticotrophic and melanocyte-stimulating peptides of the human
      pituitary were investigated by means of radioimmunoassay, bioassay and
      physicochemical procedures. Substantial amounts of adrenocorticotrophin and a
      peptide resembling beta-lipotrophin were identified in pituitary extracts, but
      alpha-melanocyte-stimulating hormone, beta-melanocyte-stimulating hormone and
      corticotrophin-like intermediate lobe peptide, which have been identified in the
      pars intermedia of pituitaries from other vertebrates, were not found. The
      absence of beta-melanocyte-stimulating hormone appears to contradict previous
      chemical and radioimmunological studies. Our results suggest, however, that it is
      not a natural pituitary peptide but an artefact formed by enzymic degradation of
      beta-lipotrophin during extraction.

PMID- 4368385
TI  - Aerial applications of ultra-low-volume insecticides to control the vector of
      Japanese encephalitis in Korea.
AB  - As a suitable emergency measure to arrest epidemics of Japanese encephalitis in
      Korea, the ultra-low-volume method of spraying insecticide to control the
      mosquito vector Culex tritaeniorhynchus has been tested in 2 successive years
      over a 16-km (2) area, utilizing a large fixed-wing aircraft. Malathion
      concentrate applied at 0.36 litres/ha gave insufficient control of the parous
      (infective) females, and no reduction in total numbers of this species.
      Fenitrothion concentrate applied at 0.45 litres/ha resulted in a 77-87% reduction
      in total numbers and an 87-98% reduction in parous females over a 4-day period.

PMID- 4368386
TI  - Affinity chromatographic differentiation of lactate dehydrogenase isoenzymes on
      the basis of differential abortive complex formation.

PMID- 4368387
TI  - Affinity chromatography of cytosolic NAD-linked glycerol-3-phosphate
      dehydrogenase from normal and neoplastic mammalian tissues.

PMID- 4368388
TI  - Affinity labeling steroids for characterization of steroid binding sites.

PMID- 4368389
TI  - Aflatoxin hepatitis (an experimental comparative study).

PMID- 4368390
TI  - Aggressive trends in endocrine surgery.

PMID- 4368391
TI  - Aldosterone production by adrenal cultures via dbcAMP, and the reversibility of
      ACTH and dbcAMP-induced changes.

PMID- 4368393
TI  - Alleviation of barbiturate inhibition on the oxidative activity of
      submitochondrial particles by alkali.

PMID- 4368392
TI  - Alkaline isomerization of ferricytochrome c: identification of the lysine ligand.
AB  - Changes in the visible absorbance spectra of complexes of horse heart cytochrome
      c hemopeptide 1-65, peptide 66-104, and their guanidinated counterparts are
      compared with those characteristic of native and fully guanidinated
      ferricytochrome c over the pH range 7 to 11. Upon raising the pH, the methionine
      ligand in the guanidinated hemopeptide 1-65.peptide 66-104 complex is replaced by
      a strong field ligand. By contrast, the methionine ligand in the hemopeptide 1
      65.guanidinated peptide 66-104 is replaced by a weak field ligand. These results
      demonstrate that lysine 13 does not ligate with the heme iron upon isomerization
      of ferricytochrome c and that the ligand in the horse heart protein is one of the
      eight lysine residues in the 66-104 segment of the polypeptide, most likely
      lysine 79.

PMID- 4368394
TI  - Allyl alcohol-induced irreversible inhibition of yeast alcohol dehydrogenase.

PMID- 4368395
TI  - Alteration of structure of level of threonyl-tRNA-synthetase in Borrelidin
      resistant mutants of E. coli.

PMID- 4368396
TI  - Alveolar cell carcinoma (bronchiolar carcinoma).

PMID- 4368397
TI  - An autopsy case of congenital hepatic cell tumor.

PMID- 4368398
TI  - An electron microscope study of mitochondrial DNA in spontaneous human tumours
      and chemically induced animal tumours.
AB  - MtDNA was extracted by a phenol method from transplanted and primary DAB induced
      hepatomata in male Wistar rats, normal rat liver, spontaneous human tumours (2
      Wilm's tumours, one neuroblastoma and one adrenal carcinoma), as well as 2
      specimens of normal human kidney, BNU induced "leukaemias" in mice and CHO
      fibroblasts in monolayer culture. The proportion of monomers, catenated dimers
      and oligomers, open dimers and small circles was determined by electron
      microscopy of the fractions comprising lower and middle DNA bands in a CsCl-EthBr
      gradient. Tumours were compared where possible with their normal tissue of
      origin. Open dimers were found in 2 Wilm's tumours and their attached "normal
      looking" kidney tissue but not in normal, non-malignant kidney or any other
      tissue studied. In Wilm's tumours, the occurrence of open dimers is far from
      being an all-or-none phenomenon. Malignancy produced little change in the
      relative proportions of catenated dimers and oligomers in the tissues studied.
      Small circles were found associated with mtDNA from every tissue. Tumour mtDNA
      was not more heterogeneous in length than monomers from the corresponding normal
      tissue, neither was the mean length of tumour mtDNA significantly different from
      its corresponding normal mtDNA.

PMID- 4368399
TI  - An epidemiologic and serologic comparison of uterine carcinoma in situ and
      squamous dysplasia.

PMID- 4368400
TI  - An examination of the constancy of the rate of molecular evolution.

PMID- 4368401
TI  - An improved spectrophotometric assay for ribulosebisphosphate carboxylase.

PMID- 4368402
TI  - An in vitro study of mineralocorticoid binding proteins from rat kidney.

PMID- 4368403
TI  - An inactivator for the affinity labelling of adenine nucleotide dependent
      enzymes.

PMID- 4368405
TI  - An overview on new procedures in surgery of the hand.

PMID- 4368404
TI  - An investigation of media for the long term storage of three respiratory viruses.

PMID- 4368406
TI  - An unusual lipid-protein complex observed in an IgG myeloma patient.

PMID- 4368407
TI  - Analysis of intact gangliosides by mass spectrometry. Comparison of different
      derivatives of a hematoside of a tumour and the major monosialoganglioside of
      brain.

PMID- 4368408
TI  - Analysis of labeled 3' terminal nucleotides of DNA fragments.

PMID- 4368409
TI  - Analysis of molecular species of 2H-labelled phosphatidylcholines by liquid-gel
      chromatography and gas chromatography-mass spectrometry.

PMID- 4368410
TI  - Analytical study of microsomes and isolated subcellular membranes from rat liver.
      IV. Biochemical, physical, and morphological modifications of microsomal
      components induced by digitonin, EDTA, and pyrophosphate.
AB  - Isopycnic equilibration and sedimentation rate studies of rat liver microsomes
      led previously to the assignment of microsomal constituents into group a1
      (monoamine oxidase), group a2 (5'-nucleotidase, alkaline phosphodiesterase I,
      alkaline phosphatase and cholesterol), group a3 (galactosyltransferase), group b
      (NADH cytochrome c reductase, NADPH cytochrome c reductase, aminopyrine
      demethylase, cytochrome b(5) and P 450), and group c (glucose 6-phosphatase,
      esterase, nucleoside diphosphatase, beta-glucuronidase and
      glucuronyltransferase). Confirmation and extension of the assignment into groups
      has been obtained by studying the differential effect of the reagents digitonin,
      EDTA, and PPi. Digitonin specifically affected the equilibrium density only of
      the group a2 and (to a lesser extent) group a3, and not of groups b and c under
      conditions which preserved the structure-linked latency of nucleoside
      diphosphatase and galactosyltransferase. Within experimental error the rate of
      sedimentation of all microsomal constituents was unaffected. The morphological
      appearance under the electron microscope was indistinguishable from that of
      nondigitonin-treated microsomes, except that a few smooth membranes (< 10%)
      exhibited broken-looking profiles. Treatment of microsomes with EDTA or PPi
      detached a substantial part of RNA and released protein in excess over the amount
      accountable for by detachment of ribosome constituents. This detachment was
      confirmed by electron microscopy. EDTA and PPi decreased markedly the equilibrium
      density and the density dispersion of groups b and c, due mainly to the uncoating
      of rough elements. EDTA and PPi shifted slightly the distribution profiles of
      groups a towards lower densities, possibly as a result of the release of adsorbed
      proteins. The combination of EDTA and digitonin, used subsequently, rendered the
      average equilibrium density of group a2 higher than that of groups b and c. Dense
      subfractions were thus enriched in constituents of group a2 and showed mainly
      broken-looking vesicles under the electron microscope. The import of our results
      on the biochemical and enzymic properties of the subcellular components of the
      microsome fractions is discussed.

PMID- 4368412
TI  - Androgen-receptor cycling in prostate cells.

PMID- 4368411
TI  - Androgen transport and receptor mechanisms in testis and epididymis.

PMID- 4368413
TI  - Androgens in the human fetus.

PMID- 4368414
TI  - Androgens. I. A review of current research on the binding and mechanism of action
      of androgenic steroids, notably 5 alpha-dihydrotestosterone.

PMID- 4368415
TI  - Animal DNA-dependent RNA polymerases. 10. General enzymatic properties of
      purified calf thymus RNA polymerases AI and B.

PMID- 4368416
TI  - Anomeric specificity of enzymes of D-glucose metabolism.

PMID- 4368417
TI  - Anterior hypophysial function in the posterior-hypophysectomized rat: normal
      regulation of the adrenal system.

PMID- 4368418
TI  - Anti-allergic actions of disodium cromoglycate and other drugs known to inhibit
      cyclic 3',5'-nucleotide phosphodiesterase.

PMID- 4368419
TI  - Antiasthmatic drugs. II. Therapeutic aspects.

PMID- 4368421
TI  - Antibodies to Epstein-Barr virus, cytomegalovirus, and Australia antigen in
      Hodgkin's disease.

PMID- 4368420
TI  - Antibodies to Epstein-Barr and other viruses in children with acute lymphoblastic
      leukaemia.

PMID- 4368422
TI  - Antibody response of susceptible and resistant chickens (type-II leukosis)
      infected with JM and JM-V leukosis strains and herpesvirus of turkeys (HVT).

PMID- 4368424
TI  - Appearance of cytotoxic T cells in cerebrospinal fluid of mice with ectromelia
      virus-induced meningitis.

PMID- 4368423
TI  - Anticonvulsant activity and inhibition of respiration in rat brain homogenates by
      substituted oxadiazoles.

PMID- 4368425
TI  - Application of spin-labeled vitamin B6 analogues for the study of aspartate
      aminotransferase.

PMID- 4368427
TI  - Aqueous humour dynamics in ocular hypertension.

PMID- 4368426
TI  - Applications of kinetic methods to aminoacyl-tRNA synthetases.

PMID- 4368428
TI  - Arabinose (fucose) dehydrogenase from pig liver. II. Steady-state kinetics.

PMID- 4368430
TI  - Arrestovisography, a method for objective assessment of visual acuity.
      Demonstration of the apparatus.

PMID- 4368429
TI  - Aromatization of testosterone by human placental microsomes under the presence of
      sex hormone-binding globulin and 17 beta-estradiol.

PMID- 4368432
TI  - Aspects of experimental hepatocarcinogenesis. II. Hyperplastic nodules.

PMID- 4368431
TI  - Ascorbic acid-like effect of the soluble fraction of rat brain on adenosine
      triphosphatases and its relation to catecholamines and chelating agents.

PMID- 4368433
TI  - Aspects of the blood-aqueous barrier with special reference to the penetration of
      antibiotics.

PMID- 4368434
TI  - Association of herpes simplex type 2 virus with cervical cancer of the uterus.

PMID- 4368436
TI  - Atypical lymphocytes. Morphologic features.

PMID- 4368435
TI  - Association of viral and mycoplasma infections with exacerbations of asthma.

PMID- 4368437
TI  - Automatic determination of the N-terminal sequence of cytochrome C from the
      insect Ceratitis capitata.

PMID- 4368438
TI  - Autoradiographic analysis of gonadotropin binding to rat ovarian tissue sections.

PMID- 4368439
TI  - Autoradiography with a position sensitive counter.

PMID- 4368440
TI  - Availability of zinc in leavened and unleavened wholemeal wheaten breads as
      measured by solubility and uptake by rat intestine in vitro.

PMID- 4368441
TI  - Axonal degeneration in the sural nerves of cancer patients.

PMID- 4368442
TI  - Axonal transport in the retinal ganglion cells of the rabbit under different
      experimental conditions.

PMID- 4368443
TI  - ACTH-induced protein release from the perfused cat adrenal gland: evidence for
      exocytosis?

PMID- 4368445
TI  - Bacteriocin susceptibility of Clostridium perfringens: a provisional typing
      schema.
AB  - Ninety-four strains of Clostridium perfringens were examined for bacteriocin
      production. Bacteriocins produced by ten of these strains were selected for
      typing 274 cultures of C. perfringens. The bacteriocins were prepared by growing
      the producer strains in broth and precipitating the active principle from the
      supernatant fluids of centrifuged cultures with ammonium sulfate. All
      bacteriocins were titrated against a common indicator strain, adjusted to
      equivalent titers, and spotted onto blood agar plates seeded with the test
      organisms. Fifty different bacteriocin sensitivity patterns were observed. These
      patterns were organized into seven groups bearing some relationship, and the
      largest number of strains falling into any one pattern did not exceed 16% of the
      total strains tested. Ninety-nine percent of all isolates were typable. The new
      method should prove useful in studies where strains must be fingerprinted.

PMID- 4368444
TI  - Bacitracin biosynthesis by three complementary fractions from Bacillus
      licheniformis.

PMID- 4368446
TI  - Baro- and chemoreceptor mechanisms in haemorrhage.

PMID- 4368447
TI  - Basis for the selectivity of action of the polymyxin antibiotics on cell
      membranes.

PMID- 4368448
TI  - Binding and degradation of low density lipoproteins by cultured human
      fibroblasts. Comparison of cells from a normal subject and from a patient with
      homozygous familial hypercholesterolemia.

PMID- 4368449
TI  - Binding of acetylcholine and cholinergic drugs to proteolipid fractions from rat
      cerebral cortex and to phospholipids from bovine brain.

PMID- 4368450
TI  - Binding of heparin in vitro and in vivo to plasma proteins.

PMID- 4368452
TI  - Binding of UGA to wild type and suppressor tryptophan tRNA from E. coli.

PMID- 4368451
TI  - Binding of thyroid stimulators to thyroid membranes.

PMID- 4368455
TI  - Biogenic amines and affective disorders.

PMID- 4368453
TI  - Bioassay of oxytocin on the superfused mammary gland of the mouse, using an
      automatic apparatus.
AB  - 1 A sensitive method of assaying oxytocin using the superfused mouse mammary
      gland is described. The method is shown to be reliable, accurate and precise.
      Assays are performed automatically and the preparation is stable for at least 18
      hours.2 The preparation is relatively insensitive to bradykinin, histamine, 5
      hydroxytryptamine, angiotensin, prostaglandin F(2alpha), adrenaline and
      noradrenaline. The contractions produced by acetylcholine can be abolished by
      atropine without the sensitivity to oxytocin being affected.3 Vasopressin has a
      variable activity on the preparation; its potency can be as high as one-fifth
      that of oxytocin.4 It is concluded that this method compares favourably with
      other published methods.

PMID- 4368454
TI  - Biochemical effects of ellipticine on leukemia L1210 cells.

PMID- 4368456
TI  - Biosynthesis of membrane teichoic acid: role of the D-alanine-activating enzyme
      and D-alanine: membrane acceptor ligase.

PMID- 4368457
TI  - Biosynthesis of valinomycin.

PMID- 4368460
TI  - Blood volume of adult germfree and conventional rats.

PMID- 4368458
TI  - Biosynthesis of water-soluble vitamins.

PMID- 4368459
TI  - Biosynthesis, physiologic role and normal patterns of lipoproteins in normal
      human plasma.

PMID- 4368461
TI  - Bluetongue and related viruses in Ibadan, Nigeria: serologic comparison of
      bluetongue, epizootic hemorrhagic disease of deer, and Abadina (Palyam) viral
      isolates.

PMID- 4368463
TI  - Bone marrow and thymus regeneration is a condition for thymoma development.

PMID- 4368462
TI  - Bluetongue and related viruses in Ibadan, Nigeria: serologic studies of
      domesticated and wild animals.

PMID- 4368464
TI  - Brain stem encephalitic lesions and schizophrenia. A report of 3 cases.

PMID- 4368465
TI  - Calcinosis.

PMID- 4368466
TI  - Calcium-binding phosphoprotein from pig brain: identification as a calcium
      dependent regulator of brain cyclic nucleotide phosphodiesterase.

PMID- 4368467
TI  - Can benign lymphadenosis (lymphomatosis) of the orbit occasionally be a
      paraneoplasia?

PMID- 4368468
TI  - Canine herpesvirus infection: literature review and case report.

PMID- 4368469
TI  - Canrenoate in normal man.

PMID- 4368471
TI  - Carbohydrate metabolism in shock resistance.

PMID- 4368470
TI  - Carbohydrate metabolism in rat uterus during the oestrous cycle.

PMID- 4368472
TI  - Carcinoma complicating a benign teratoma of the rectum: Report of a case.

PMID- 4368473
TI  - Case records of the Massachusetts General Hospital. Weekly clinicopathological
      exercises. Case 37-1974.

PMID- 4368474
TI  - Case records of the Massachusetts General Hospital. Weekly clinicopathological
      exercises. Cases 38-1974.

PMID- 4368475
TI  - Ca2+-induced lateral phase separations in phosphatidic acid-phosphatidylcholine
      membranes.

PMID- 4368476
TI  - Cell fusion by the antigen-antibody complex of Sendai virus studied by electron
      microscopy.

PMID- 4368477
TI  - Cell surface glycolipid and glycoprotein glycosyltransferases of normal and
      transformed cells.

PMID- 4368478
TI  - Cell surface immunoglobulin. VI. Dynamics on a human lymphoma line.

PMID- 4368479
TI  - Cell transformation mutants are not susceptible to growth activation by
      fibroblast growth factor at permissive temperatures.

PMID- 4368481
TI  - Central nervous influence upon the adrenocortical reaction during stress
      situations.

PMID- 4368482
TI  - Cerebral scintigraphy with a Nuclear Chicago 1206 high performance gamma camera.

PMID- 4368480
TI  - Cellular action of antidiuretic hormone in mice with inherited vasopressin
      resistant urinary concentrating defects.
AB  - Previous work has suggested that resistance to vasopressin in two strains of mice
      with nephrogenic deficiency of urinary concentration may entail a defect in the
      action of vasopressin at the cellular level. Several components involved in this
      action were therefore examined in vitro in renal medullary tissues from control
      mice (genotype VII +/+) and two genotypes with mild diabetes insipidus (DI +/+
      nonsevere) and marked (DI +/+ severe) vasopressin-resistant concentrating
      defects. No significant differences were found in the affinity of adenylate
      cyclase for [8-arginine]-vasopressin (AVP), tested over a range of hormone
      concentration from 10(-10) to 10(-5) M. However, maximal stimulation of adenylate
      cyclase by saturating concentrations of AVP (intrinsic activity) was markedly
      decreased from control values in DI +/+ severe mice, and decreased to a lesser
      extent in DI +/+ nonsevere animals. A significant correlation was found between
      the activity of adenylate cyclase maximally stimulated by AVP in a given
      genotype, and the urine osmolality in the same animals. There were no significant
      differences in maximal stimulation of renal medullary adenylate cyclase in
      control experiments: not when stimulated nonspecifically by sodium fluoride, nor
      when stimulated by AVP in tissues from rats with induced water diuresis as
      compared to antidiuretic rats. Nor were there significant differences between VII
      +/+ and DI +/+ severe mice in the activity of renal cortical adenylate cyclase,
      either basal or when stimulated by parathyroid hormone. Furthermore, the abnormal
      genotypes did not differ significantly from control mice in the renal medullary
      activities of cyclic AMP phosphodiesterase or cyclic AMP-dependent protein
      kinase, nor in the content of microtubular subunits (assessed as
      colchicinebinding protein). The results are compatible with the view that
      impaired stimulation of renal medullary adenylate cyclase by vasopressin might be
      the sole or contributing cause of the vasopressin-resistant concentrating defect
      in the diseased mice; however, a causal relationship has not yet been proved.

PMID- 4368483
TI  - Changes in plasma corticosterone and hypothalamic CRF levels following
      intraventricular injection or drug-induced changes of brain biogenic amines in
      the rat.

PMID- 4368484
TI  - Characteristics of vesicular stomatitis virus envelopes released with saponin.

PMID- 4368485
TI  - Characterization of a novel nicotinamide adenine dinucleotide-dependent alcohol
      dehydrogenase from a strain of Streptococcus mutans.

PMID- 4368486
TI  - Characterization of bromodeoxyuridine-induced endogenous guinea pig virus.
AB  - An endogenous virus (GPV) was induced after 5-bromodeoxyuridine treatment of
      cultured guinea pig cells. Compared to Gross murine leukemia virus (G-MuLV) GPV
      has a reproducibly heterogenous density of about 1.16 to 1.18 g/ml. The virion
      associated RNA is slightly larger than that in G-MuLV. Sodium dodecyl sulfate
      polyacrylamide gel electrophoretic analysis of dissociated GPV resolved five
      major structural proteins: I (molecular weight 70,000), II (molecular weight
      36,000), III (molecular weight 24,000), IV (molecular weight 18,000), and V
      (molecular weight 16,000) which are similar to but distinct from G-MuLV proteins.
      Proteins I and II were demonstrated to be glycoproteins by incorporation of
      [(3)H]glucosamine. GPV and G-MuLV did not have any appreciable genetic homology
      or any common group-specific antigens when analyzed by immunodiffusion,
      radioimmunoassay, and indirect immunofluorescence. Morphogenesis of GPV also
      differed from that of a typical type C oncornavirus and proceeded via two
      pathways: (i) a majority of virus particles were formed in cytoplasmic vacuoles
      and were released after cellular disruption; and (ii) a minor population of
      particles were assembled in the cytoplasmic matrix and then migrated to the
      plasma membrane where they budded into the extracellular space. To date, GPV has
      been unable to initiate or maintain a productive replication in any cell line
      tested.

PMID- 4368487
TI  - Characterization of lactose-fermenting revertants from lactose-negative
      Streptococcus lactis C2 mutants.
AB  - Partial lactose-fermenting revertants from lactose-negative (lac(-)) mutants of
      Streptococcus lactis C2 appeared on a lawn of lac(-) cells after 3 to 5 days of
      incubation at 25 C. The revertants grew slowly on lactose with a growth response
      similar to that for cryptic cells. In contrast to lac(+)S. lactis C2, the
      revertants were defective in the accumulation of [(14)C]thiomethyl-beta-d
      galactoside, indicating that they were devoid of a transport system. Hydrolysis
      of o-nitrophenyl-beta-d-galactoside-6-phosphate by toluene-treated cells
      confirmed the presence of phospho-beta-d-galactosidase (P-beta-gal) in the
      revertant. However, this enzyme was induced only when the cells were grown in the
      presence of lactose; galactose was not an inducer. In lac(+)S. lactis C2, enzyme
      induction occurred in lactose- or galactose-grown cells. The revertants were
      defective in EII-lactose and FIII-lactose of the phosphoenolpyruvate-dependent
      phosphotransferase system. Galactokinase activity was detected in cell extracts
      of lac(+)S. lactis C2, but the activity was 9 to 13 times higher in extracts from
      the revertant and lac(-), respectively. This suggested that the lac(-) and the
      revertants use the Leloir pathway for galactose metabolism and that galactose-1
      phosphate rather than galactose-6-phosphate was being formed. This may explain
      why lactose, but not galactose, induced P-beta-gal in the revertants. Because the
      revertant was unable to form galactose-6-phosphate, induction could not occur.
      This compound would be formed on hydrolysis of lactose phosphate. The data also
      indicate that galactose-6-phosphate may serve not only as an inducer of the
      lactose genes in S. lactis C2, but also as a repressor of the Leloir pathway for
      galactose metabolism.

PMID- 4368488
TI  - Characterization of protein kinases forming acid-labile histone phosphates in
      Walker-256 carcinosarcoma cell nuclei.

PMID- 4368489
TI  - Characterization of slowly interconvertible states of phosphoribosyladenosine
      triphosphate synthetase dependent on temperature, substrates, and histidine.

PMID- 4368490
TI  - Chemical and biological evolution of nucleotide-binding protein.

PMID- 4368491
TI  - Chemical and physico-chemical alterations of human erythrocytes by periodate,
      succinic anhydride, 2-phenylethanol, and 1,1-dimethylphenylethanol: effects on
      membrane permeability and on metabolism of intact cells and hemolysates.

PMID- 4368492
TI  - Chemical determination of oestrogen distribution in the foetus and placenta of
      the domestic pig.

PMID- 4368493
TI  - Chemotherapy in intraocular metastasis from carcinoma of the breast.

PMID- 4368494
TI  - Children's mental health services: a case study of a successful grant proposal.

PMID- 4368496
TI  - Chloroquine-induced ultrastructural changes in the pigment epithelium of the
      albino rat.

PMID- 4368495
TI  - Chinese hamster hypoxanthine-guanine phosphoribosyltransferase. Purification,
      structural, and catalytic properties.

PMID- 4368497
TI  - Cholangiofibrosis induced by short-term feeding of 3'-methyl-4
      (dimethylamino)azobenzene: an electron microscopic observation.

PMID- 4368498
TI  - Cholinergic stimulation of phospholipid labelling from (32P) orthophosphate in
      guinea-pig cortex synaptosomes in vitro: subsynaptosomal localization.

PMID- 4368499
TI  - Chromatin-associated DNA endonuclease activities in HeLa cells.

PMID- 4368500
TI  - Chromatographic changes in specific tRNAs after reaction with cyanogen bromide
      and sodium periodate.

PMID- 4368501
TI  - Chronic aggressive hepatitis. Report of a case with virus like particles in the
      liver.

PMID- 4368502
TI  - Chronic cyclitis in children.

PMID- 4368503
TI  - Circular dichroism of DNA in the vacuum ultraviolet.

PMID- 4368504
TI  - Circular dichroism spectra of DNA of high adenine plus thymine content.

PMID- 4368505
TI  - Cleavage of 23-S RNA in 50-S ribosomes into a 5'-terminal and a 3'-terminal
      fragment by pancreatic ribonuclease.

PMID- 4368506
TI  - Clinical and pathological effects of streptozotocin.

PMID- 4368507
TI  - Clinical disorders of sleep.

PMID- 4368508
TI  - Clinical evaluation of endolymphatic radiotherapy in malignant lymphoma.

PMID- 4368509
TI  - Clinical immunology and the physician. Blood.

PMID- 4368511
TI  - Clusters in lipid bilayers and the interpretation of thermal effects in
      biological membranes.

PMID- 4368510
TI  - Clinical significance of circulating hormonal substances.

PMID- 4368512
TI  - Cold agglutinin production and cytomegalovirus infection.

PMID- 4368513
TI  - Colitis cystica profunda, an unusual solitary tumor: Report of three cases.

PMID- 4368514
TI  - Collagenases (first of three parts).

PMID- 4368515
TI  - Collagenases (second of three parts).

PMID- 4368516
TI  - Collagenases (third of three parts).

PMID- 4368517
TI  - Combined use of 99mtechnetium-labelled macroaggregates of albumin and 75selenium
      selenomethionine in the diagnosis of lung cancer.

PMID- 4368518
TI  - Comparative effects of prostaglandins A2 and B2 on vascular and airway
      resistances and adrenergic neurotransmission.

PMID- 4368519
TI  - Comparative studies on mitochondrial development in yeasts. 3. Growth-phasic
      effects of antibiotics on mitochondrial differentiation in Candida.

PMID- 4368520
TI  - Comparison between different techniques of immuno-protection in the A-SW mouse
      SEWA tumour system.
AB  - Various procedures for immunoprotection in the A-SW mouse SEWA tumour system were
      compared. Four types of protector agents were used: polyoma virus, allogeneic
      S724 cells, A9/SEWA hybrid cells and xenogeneic ST(py) cells. Several injection
      schedules were also employed. On the whole, reasonable immunoprotection was
      obtained. The results, when allogeneic hybrid or xenogeneic cells were used, were
      comparable with those obtained for polyoma virus. This indicates that the
      T.A.T.A. of the SEWA tumour had been well conserved. When polyoma virus alone was
      used as the protector agent, injection 7 days before the tumour challenge, or
      iterative injection, afforded better protection than a single injection on the
      day of challenge.

PMID- 4368521
TI  - Comparison between the effect of luteinizing hormone and prostaglandin E1 on
      ovarian cyclic AMP.

PMID- 4368522
TI  - Comparison of actions of papaverine, aspaminol and isoprenaline on isolated rat
      uterus.

PMID- 4368523
TI  - Comparison of analysis of isoniazid and its dosage forms by several methods.

PMID- 4368524
TI  - Comparison of immunoglobulin formation in vitro by leukocytes of normal donors
      and steroid- and nonsteroid-treated asthmatic patients.

PMID- 4368525
TI  - Comparison of somatic mutation rates induced in Tradescantia by chemical and
      physical mutagens.

PMID- 4368527
TI  - Comparison of the properties of glucosaminephosphate isomerase (glutamine
      forming) from rat liver and a hepatoma.

PMID- 4368526
TI  - Comparison of the presynaptic actions of botulinum toxin and beta-bungarotoxin on
      neuromuscular transmission.

PMID- 4368528
TI  - Compartmentalization of murein hydrolases in the envelope of Escherichia coli.

PMID- 4368530
TI  - Conformation changes in cytochrome c2 from Rhodospirillum rubrum.

PMID- 4368529
TI  - Concentration of amino acids in aqueous humour and plasma in congenital cataract
      or dislocation of the lens.

PMID- 4368531
TI  - Conformation of cyclic beta-adenosine 3',5'-phosphate in solution using the
      lanthanide shift technique.

PMID- 4368532
TI  - Conformational differences in myosin. Evidence for change in rate limiting step
      of the magnesium stimulated ITPase of myosin.

PMID- 4368533
TI  - Conjugated estrogen therapy and tests of thyroid function.

PMID- 4368534
TI  - Consideration of potential parasite food hazards.

PMID- 4368535
TI  - Constant occurrence of adrenocortical tissue in the juvenile rabbit ovary.

PMID- 4368536
TI  - Control of membrane lipid fluidity in Acholeplasma laidlawii.

PMID- 4368538
TI  - Corneal reflection of a straight line and ophthalmometry in normal people and in
      asymptomatic relatives of patients with keratoconus. A preliminary report.

PMID- 4368537
TI  - Copper deficiency in the developing rat brain: a possible model for Menkes'
      steely-hair disease.

PMID- 4368539
TI  - Cortisol induction of glycerol phosphate dehydrogenase in a rat brain tumour cell
      line.

PMID- 4368540
TI  - Cross-pathway regulation: histidine-mediated control of histidine, tryptophan,
      and arginine biosynthetic enzymes in Neurospora crassa.
AB  - In Neurospora crassa, histidine starvation of histidine mutants resulted in
      derepression of histidine, tryptophan, and arginine biosynthetic enzymes. The
      same tripartite derepression occurred in wild-type strain 74A when it was grown
      in medium supplemented with 3-amino-1,2,4-triazole, an inhibitor of histidine
      biosynthesis. Histidine-mediated derepression of tryptophan and arginine
      biosynthetic enzymes was not due to a lowered intracellular concentration of
      tryptophan or arginine, respectively. A discussion of possible mechanisms and of
      similar studies in prokaryotic and eukaryotic organisms is presented.

PMID- 4368541
TI  - Cross-pathway regulation: tryptophan-mediated control of histidine and arginine
      biosynthetic enzymes in Neurospora crassa.
AB  - In Neurospora crassa, the starvation of tryptophan mutants for tryptophan
      resulted in the derepression of tryptophan, histidine, and arginine biosynthetic
      enzymes. This tryptophan-mediated derepression of histidine and arginine
      biosynthetic enzymes occurred despite the fact that the tryptophan-starved cells
      had a higher intracellular concentration of histidine and arginine than did
      nonstarved cells.

PMID- 4368542
TI  - Cryptic A-like receptor sites in human erythrocyte glycoproteins: proposed nature
      of Tn-antigen.

PMID- 4368543
TI  - Cultivation of Entamoeba histolytica with bacterial associates. Isolation and
      maintenance of Taiwan strains.

PMID- 4368544
TI  - Cutting the REM nerve: an approach to the adaptive role of REM sleep.

PMID- 4368545
TI  - Cyclic adenosine monophosphate and alteration of Chinese hamster ovary cell
      morphology: a rapid, sensitive in vitro assay for the enterotoxins of Vibrio
      cholerae and Escherichia coli.
AB  - The major limitation to our understanding of the clinical importance of
      enterotoxigenic Escherichia coli in diarrheal illness has been the lack of a
      simple rapid assay for the enterotoxin produced by certain E. coli. On the basis
      of the activation of adenylate cyclase by heat-labile enterotoxin of E. coli (LT)
      and by cholera toxin (CT) in intestinal and other tissues, cultured Chinese
      hamster ovary (CHO) cells with known morphological responses to dibutyryl cyclic
      adenosine 5'-monophosphate (AMP) were exposed to these enterotoxins. Crude
      culture filtrates of LT-producing E. coli and CT stimulated cyclic AMP
      accumulation and cell elongation in CHO cells. The similarity of time course,
      concentration dependence, and potentiation by phosphodiesterase inhibitors
      suggested cyclic AMP mediation of the morphological change. Heat inactivated CT
      and LT in this system. Choleragenoid inhibited CT; antiserum against CT inhibited
      both enterotoxin effects. In contrast to culture filtrates of 16 strains of E.
      coli known to produce LT, culture filtrates from 13 E. coli that do not produce
      LT did not alter CHO cell morphology. The morphological change is a simple,
      specific assay for these enterotoxins and detect 3 x 10(-17) mol of CT or a 1:250
      dilution of crude culture filtrate of LT-producing E. coli 334.

PMID- 4368547
TI  - Cyclic guanosine 3':5'-monophosphate in Escherichia coli and Bacillus
      lichenformis.

PMID- 4368546
TI  - Cyclic adenosine 3':5'-monophosphate metabolism in normal and SV40-transformed WI
      38 cells.

PMID- 4368548
TI  - Cyclic guanosine-3':5'-monophosphate induced diuresis in rats.

PMID- 4368549
TI  - Cyclic nucleotide levels during spontaneous uterine contractions.

PMID- 4368550
TI  - Cyclic nucleotides in higher plants?

PMID- 4368551
TI  - Cyclic AMP and anxiety.

PMID- 4368552
TI  - Cyclic AMP and the immune response;.

PMID- 4368554
TI  - Cyclic AMP and the triggering of the decidual reaction.

PMID- 4368553
TI  - Cyclic AMP and the transformation of fibroblasts.

PMID- 4368556
TI  - Cytochalasin B: aspects of phagocytosis in nutrient uptake in Tetrahymena.

PMID- 4368555
TI  - Cytarabine treatment of progressive multifocal leukoencephalopathy. Clinical
      course and detection of virus-like particles after antiviral chemotherapy.

PMID- 4368558
TI  - Cytochrome c peroxidase catalyzed oxidation of ferrocyanide by hydrogen peroxide.
      Transient state kinetics.

PMID- 4368557
TI  - Cytochrome c peroxidase catalyzed oxidation of ferrocyanide by hydrogen peroxide.
      Steady-state kinetics.

PMID- 4368560
TI  - Cytochrome P450 associated with free hepatic polyribosomes.

PMID- 4368559
TI  - Cytochrome c: a thermodynamic study of the relationship among oxidation state,
      ion-binding and structural parameters. Cation binding to horse-heart
      ferrocytochrome c.

PMID- 4368561
TI  - Cytosol-binding protein of thyroxine and triiodothyronine in human and rat kidney
      tissue.

PMID- 4368562
TI  - D(-)-beta-hydroxybutyrate dehydrogenase activity in cloned cell lines of glial
      and neuronal origin.

PMID- 4368563
TI  - Death and dying--oncology discussion group.

PMID- 4368564
TI  - Demodicosis in the Mongolian gerbil (Meriones unguiculatus): a case report.

PMID- 4368565
TI  - Demonstration of alpha-Fetoglobulin in hepatoma tissue by fluorescent antibody
      technique.

PMID- 4368566
TI  - Demonstration of protease-like activity in human serum low density lipoprotein.

PMID- 4368568
TI  - Deoxyglucose transport changes in murine sarcoma virus-infected cells-a
      quantitative assay for virus transforming activity.

PMID- 4368567
TI  - Density changes in herpesvirus-infected cells.

PMID- 4368569
TI  - Deoxyribonucleic acid-dependent ribonucleic acid polymerase activity in purified
      Chlamydia trachomatis initial bodies.

PMID- 4368570
TI  - Design consideration for long-acting antagonists.

PMID- 4368571
TI  - Detection of antibodies against virally-induced tumor-associated antigens by
      mixed hemadsorption.

PMID- 4368572
TI  - Detection of cardiac damage using a steady state assay for lactate dehydrogenase
      isoenzymes in serum.

PMID- 4368573
TI  - Detection of tumor-virus associated antibodies by mixed hemadsorption.

PMID- 4368574
TI  - Detection of Epstein-Barr virus (EBV)-associated nuclear antigen in human
      lymphoblastoid cell lines by means of an 125-I-IgG-binding assay.

PMID- 4368575
TI  - Determination of glycerol dehydratase activity by the coupled enzymic method.

PMID- 4368576
TI  - Determination of the absolute hand of the helix in the nucleocapsid of
      haemagglutinating virus (Japan).

PMID- 4368577
TI  - Determination of the age of some anopheline mosquitos by daily growth layers of
      skeletal apodemes.
AB  - Earlier work has shown that it is possible to determine the calendar age of Culex
      and Aedes mosquitos by counting the daily layers of cuticular growth on the inner
      apodemes. In view of the epidemiological importance of age grouping in Anopheles
      species, the applicability of the method to this genus was studied in both
      laboratory-reared and field-collected specimens. In the four species examined, it
      was found possible to distinguish daily growth layers for periods of up to 10-13
      days provided that proper staining procedures are used.

PMID- 4368578
TI  - Determination of the catalytically active unit of fructose 1,6-diphosphatase from
      rabbit liver.

PMID- 4368579
TI  - Determination of the vanadium content of protein solutions by electron
      paramagnetic resonance spectroscopy.

PMID- 4368580
TI  - Development of an inexpensive cell culture medium for the production of foot-and
      mouth disease vaccine.

PMID- 4368581
TI  - Development of methods for detecting viruses in solid waste landfill leachates.
AB  - Methods were developed for detecting and concentrating enteric viruses in
      municipal solid waste landfill leachates. Poliovirus added to a leachate was not
      readily detectable, possibly because the virus was adsorbed to the leachate
      particulates. The masking effects associated with suspended solids in the
      leachate were overcome by adding a final 0.1 M sodium
      (tetra)ethylenediaminetetraacetate concentration to the leachate. A sodium
      (tetra)ethylenediaminetetraacetate-treated leachate could be clarified by
      filtration at pH 8.0 without a loss of virus. The clarified and sodium
      (tetra)ethylenediaminetetraacetate-treated leachate contained interfering
      materials of an anionic nature which prevented virus adsorption to epoxy-fiber
      glass filters. This interfering effect was overcome by treating the leachate with
      an anion-exchange resin. Viruses in the resin-treated leachate were concentrated
      by adjusting the leachate to pH 3.5, adding AlCl(3) to a final 0.005 M
      concentration, adsorbing the viruses to an epoxy-fiber glass virus adsorbent, and
      eluting the adsorbed viruses in a small volume. When this method was used to
      concentrate poliovirus 100-fold in a variety of leachates, the average virus
      recovery efficiency was 37%. With the methods described in this study, it should
      be possible to efficiently monitor solid waste disposal site leachates for
      enteric viruses.

PMID- 4368582
TI  - Development of Periplaneta americana (L.) cell cultures and their infection with
      enteroviruses.

PMID- 4368583
TI  - Developmental changes of steryl esters in normal and jimpy mouse brain.

PMID- 4368584
TI  - Developments in monitoring human populations for mutation rates.

PMID- 4368585
TI  - Diagnosis of recent Herpes simplex infections. A modified immunofluorescent test
      for the detection of specific Herpes simplex IgM antibodies after staphylococcal
      adsorption of IgG.

PMID- 4368586
TI  - Dielectric measurements of Nitellopsis obtusa cells with intracellular
      electrodes.

PMID- 4368587
TI  - Differential effects of Mg2+ on various hydrolytic and synthetic activities of
      multifunctional glucose-6-phosphatase.

PMID- 4368588
TI  - Differential properties of prostaglandin and gonadotropin receptors in the bovine
      corpus lutuem cell membranes.

PMID- 4368589
TI  - Differential spermatogenic response of mice to the induction of mutations by
      antineoplastic drugs.

PMID- 4368590
TI  - Differentiation of type A foot-and-mouth disease virus subtypes by double- and
      radial-immunodiffusion analysis.

PMID- 4368591
TI  - Diguanosinetetraphosphate guanylohydrolase in Artemia salina.

PMID- 4368592
TI  - Diphenylhydantoin treatment of glycogen storage diseases.

PMID- 4368593
TI  - Distribution and some properties of acid phosphatase in the 7,12
      dimethylbenz(alpha) anthracene-induced rat-mammary carcinoma.

PMID- 4368594
TI  - Disturbances of the hypothalamo-hypophysial-adrenocortical system in the alloxan
      diabetic rat.

PMID- 4368595
TI  - Divergent synaptic influences affecting discharge patterning of genioglossus
      motor units.

PMID- 4368596
TI  - Dopamine-beta-hydroxylase activity in cholinergic neuroblastoma times glioma
      hybrid cells; increase of activity by N6,O2'-dibutyryl adenosine 3':5'-cyclic
      monophosphate.

PMID- 4368597
TI  - Dopamine-induced inhibition of synaptic transmission in the inferior mesenteric
      ganglion of the dog.

PMID- 4368598
TI  - Dose response analysis of 0.1 per cent, 0.5 per cent, 1.0 per cent, and 2.0 per
      cent epinephrine in chronic open-angle glaucoma.

PMID- 4368600
TI  - Duck viral enteritis: microtiter plate isolation and neutralization test using
      the duck embryo fibroblast cell line.

PMID- 4368601
TI  - Duodenal calcium binding protein in the chick: a new bioassay for vitamin D.

PMID- 4368599
TI  - Drinking induced by injections of angiotensin into forebrain and mid-brain sites
      of the monkey.
AB  - 1. Unilateral and bilateral injections of 1.0 mul. solutions of angiotensin II
      into specific brain sites produced copious drinking of water in the water-replete
      rhesus monkey (Macaca mulatta).2. Of six brain regions in seven monkeys into
      which a total of 368 microinjections of angiotensin II were made, three were
      sensitive to angiotensin II. In decreasing order of sensitivity, they were (i) a
      rostral zone that included the septum, the anterior hypothalamus and the preoptic
      region, (ii) a caudal zone consisting of the mesencephalic central grey, and
      (iii) the lateral and third ventricles near the foramen of Monro. Of the regions
      tested, those that were relatively inactive included (i) the mid line thalmus,
      (ii) the mid-brain reticular formation, and (iii) metencephalic points in the
      cerebellum, the 4th ventricle and the dorsal aspect of the pons.3. Bilateral
      microinjections of angiotensin II into the sensitive regions in doses as low as
      0.75-6 ng were dipsogenic and, with increasing doses, drinking occurred in a dose
      dependent fashion up to 500 ng, after which the amount drunk levelled off or was
      reduced. The dose-response curve for unilateral microinjections began at 12.5 ng,
      and at doses higher than 50 ng unilateral and bilateral microinjections were
      equipotent.4. The onset of drinking (without eating) averaged 2.1-3.2 min
      following the end of microinjections for all sensitive tissue sites. Injections
      into the ventricles produced significantly longer drinking latencies.5.
      Angiotensin I elicited drinking in amounts comparable to angiotensin II at a dose
      of 100 ng whereas analogues of angiotensin II were weak dipsogens. Of the three
      analogues tested, Phe(4), Tyr(8)-angiotensin II was the most potent dipsogen,
      followed by Ile(8)-angiotensin II. The 1-7 heptapeptide, des-Phe(8)-angiotensin
      II was an ineffective dipsogen. Carbachol microinjected into the most sensitive
      angiotensin drinking sites had no dipsogenic action in the water-replete
      monkey.6. Tachyphylaxis to angiotensin II was demonstrated as a reduction in mean
      water intake of 55 and 74 per cent on the second and third microinjections,
      respectively. This reduction appeared to be due to dilutional inhibition or
      signals from the amount of water ingested on the first microinjection of
      angiotensin II.7. Monkeys drank an amount equal to a normal daily intake
      following two to three microinjections of angiotensin II in doses of 100-250 ng
      into sensitive regions. This extra water load caused no reductions in normal
      daily water intake either for the remainder of the experimental day or 24 hr
      later.8. Pre-treatments with microinjections of an angiotensin-converting enzyme
      inhibitor, SQ 20,881, did not reduce the dipsogenic action of angiotensin I,
      suggesting that this and perhaps other peptide precursors act directly on
      receptor mechanisms to produce drinking. Attempts to change the polydipsic
      effects of angiotensin II were unsuccessful with pre-treatments of intracranial
      microinjections of either haloperidol, Ile(8)-angiotensin II or carbachol.9.
      Microinjections of angiotensin II dissolved in hypertonic saline solutions had no
      influence on water intake when compared with the same dose dissolved in distilled
      water or isotonic saline.10. Yawning was the only other response that appeared to
      be related directly to intracranial injections of angiotensin II. In some
      instances, a hyperactive state of the animal followed intraventricular injections
      of angiotensin II. In other instances, intracranial microinjections of
      angiotensin II were followed by quietude or e.e.g. and behavioural signs of light
      sleep.11. This work further confirms the findings of previous research which
      showed that angiotensin II is the most potent dipsogen in all species tested to
      date. This endogenous peptide appears to participate in natural thirst by acting
      on central mechanisms of extracellular thirst.

PMID- 4368602
TI  - Dynamics of cyclic adenosine 3',5'-monophosphate release during adrenocortical
      stimulation in vivo.

PMID- 4368603
TI  - Dyskeratotic marginal keratoconjunctivitis in hereditary periodontopathy and
      hyperkeratosis.

PMID- 4368604
TI  - Dyslipoproteinemias and diabetes mellitus.

PMID- 4368606
TI  - Editorial: Burkitt's lymphoma;.

PMID- 4368605
TI  - Ecological survey by the immunofluorescent method of virus in enzootics of avian
      encephalomyelitis.

PMID- 4368607
TI  - Editorial: New concepts in adipose tissue metabolism and obesity.

PMID- 4368608
TI  - Editorial: The endogenous factor in intestinal calcium absorption.

PMID- 4368609
TI  - Effect of aging on renal membrane-bound enzyme activities.

PMID- 4368611
TI  - Effect of chemical mediators on the K+-efflux, Ca2+-uptake and 32P-incorporation
      of erythrocytes.

PMID- 4368610
TI  - Effect of carbachol on amino acid incorporation into protein of rat pancreas in
      vitro.

PMID- 4368612
TI  - Effect of chloroquine on acid phosphatase activity in the pigment epithelium of
      the retina of albino and pigmented rats.

PMID- 4368614
TI  - Effect of cyclopentolate on the aqueous dynamics in incipient or suspected open
      angle glaucoma.

PMID- 4368613
TI  - Effect of chlorpropamide on cyclic AMP in rat renal medulla.

PMID- 4368615
TI  - Effect of cyclophosphamide on ACTH-induced kidney disease.

PMID- 4368616
TI  - Effect of drugs on the activity of thrombocytes 3,5-cyclic AMP phosphodiesterase.

PMID- 4368617
TI  - Effect of estradiol on lipolysis and adenosine 3',5'-monophosphate accumulation
      in isolated rat adipocytes.

PMID- 4368618
TI  - Effect of extracellular chondroitin sulfate on cultured chondrocytes.

PMID- 4368619
TI  - Effect of flavin adenine dinucleotide on the glucose-6-phosphate dehydrogenase
      activity of adrenal gland of hypophysectomized rats.

PMID- 4368620
TI  - Effect of fusidic acid on sporulation of Bacillus subtilis.

PMID- 4368621
TI  - Effect of glucagon, epinephrine, cyclic 3',5'-AMP, N6-2'-0-dibutyryl cyclic 3',5'
      AMP and insulin upon the phosphate exchange of the isolated perfused fed rat
      liver.

PMID- 4368623
TI  - Effect of hypervitaminosis A on the testes of the rat during lactation.

PMID- 4368622
TI  - Effect of glycine and serine in synthetic amino acid diets upon glycine and
      serine metabolism in chicks.

PMID- 4368624
TI  - Effect of immunisation with heat-killed micro-organisms on transplantation
      immunity to adenovirus-12-induced tumour cells.

PMID- 4368625
TI  - Effect of induced hypothyroidism on pituitary luteinizing hormone (LH)
      concentration in female rats.

PMID- 4368627
TI  - Effect of isoproterenol on blood pressure, plasma renin activity, and water
      intake in rats.

PMID- 4368626
TI  - Effect of inhibitors of ribonucleic acid and protein synthesis on the cyclic
      adenosine monophosphate stimulation of plasmid ColE1 replication.
AB  - Addition of cyclic adenosine 3'-5'-monophosphate (c-AMP) to growing Escherichia
      coli cells, colicinogenic for the plasmid ColE1, results in a fourfold
      stimulation in the rate of synthesis of the plasmid deoxyribonucleic acid (DNA).
      The stimulation is transient (30 min) and is succeeded by a brief period (30 min)
      of cessation of plasmid DNA replication. The stimulation of ColE1 DNA replication
      also occurs in chloramphenicol-treated cells. Rifampin inhibits ColE1 DNA
      replication in the presence or absence of c-AMP. Employing thymine starvation
      conditions to stop ColE1 DNA synthesis, it was found that c-AMP, added during the
      period of thymine starvation, effected a stimulation in the amount of subsequent
      replication which took place when replicating conditions were restored. The
      stimulatory effect of c-AMP under these conditions was not prevented by
      chloramphenicol but was completely eliminated when rifampin was present. Under
      these conditions, when rifampin was added after the effect of c-AMP was allowed
      to occur, subsequent replication of the plasmid could take place, but only one
      round of replication occurred. A model to account for the c-AMP effects is
      presented.

PMID- 4368628
TI  - Effect of paracentesis on ocular antibiotic concentration.

PMID- 4368629
TI  - Effect of phenformin on lipid transport in hypertriglyceridemia.

PMID- 4368630
TI  - Effect of phospholipase C on the permeability of the toad bladder.

PMID- 4368631
TI  - Effect of potassium sorbate on salmonellae, Staphylococcus aureus, Clostridium
      perfringens, and Clostridium botulinum in cooked, uncured sausage.
AB  - Skinless precooked, uncured sausage links with and without potassium sorbate
      (0.1% wt/wt) were inoculated with salmonellae, Staphylococcus aureus, Clostridium
      perfringens, and Clostridium botulinum and held at 27 C to represent temperature
      abuse of the product. Total counts of uninoculated product showed that the normal
      spoilage flora was delayed 1 day when sorbate was present. Growth of salmonellae
      was markedly retarded by sorbate. Growth of S. aureus was delayed 1 day in the
      presence of sorbate, after which growth occurred to the same level as in product
      without sorbate. C. perfringens declined to below detectable levels within the
      first day in product with and without sorbate. Sorbate retarded the growth of C.
      botulinum. Botulinal toxin was detected in 4 days in product without sorbate but
      not until after 10 days in product with sorbate.

PMID- 4368633
TI  - Effect of short-term increased intraocular pressure on the fine structure of the
      retina.

PMID- 4368632
TI  - Effect of schistosomal infection and of schistosomicidal drugs on the drug
      metabolizing enzymes of mouse liver.

PMID- 4368634
TI  - Effect of somatostatin on glucose induced insulin release in isolated perfused
      rat pancreas and isolated rat pancreatic islets.

PMID- 4368635
TI  - Effect of stretching on the elastic characteristics and the contractile component
      of frog striated muscle.
AB  - 1. The force-velocity relationship and the stress-strain curve of the so-called
      series elastic component (s.e.c.) of frog sartorius, semitendinosus and
      gastrocnemius have been determined during shortening against a given force
      (isotonic quick-release) and at high speed (controlled release): (a) from a state
      of isometric contraction and (b) after stretching of the contracted muscle. In
      both cases the muscle was released from the same length: this was usually
      slightly greater than the muscle's resting length.2. The muscle released
      immediately after being stretched is able to shorten against a constant force, P,
      equal to or even greater than the isometric force, P(0), at the same length. When
      the force P applied to the muscle is reduced below P(0) the velocity of
      shortening is greater after stretching, and the force-velocity curve is therefore
      shifted along the velocity axis: the shift is maximal when P is near to P(0) and
      it decreases rapidly with decreasing P.3. The extent of shortening of the s.e.c.
      required to make the force fall from P(0) to zero is 50-100% greater when the
      muscle is released immediately after stretching than when it is released from a
      state of isometric contraction. This difference is found by using either the
      controlled release method or the isotonic quick-release method.4. If a time
      interval is left between the end of stretching and the onset of shortening of the
      contracted muscle (controlled release method), the length change of the s.e.c.,
      for a given fall of the force, is reduced and approaches that taking place when
      the muscle is released from a state of isometric contraction.5. Curare does not
      affect the results described above, indicating that these do not depend on
      modification of the neuromuscular transmission.6. It is concluded that stretching
      a contracted muscle modifies temporarily: (a) its elastic characteristics, as
      shown by the greater amount of mechanical energy released for a given fall of the
      force at the muscle's extremities, and (b) its contractile machinery, as it is
      suggested by the change of the force-velocity relationship.

PMID- 4368636
TI  - Effect of vasoconstrictors on lymph oxygen tension in normo- and hypovolemia.

PMID- 4368637
TI  - Effect of DB-c-AMP on mechanical characteristics of ventricular and atrial
      preparations of several mammalian species.

PMID- 4368638
TI  - Effect of 2'-deoxythymidine on experimental herpes infection.

PMID- 4368639
TI  - Effect on growth and structure of transplantable malignant melanomas of the
      Syrian golden hamster (Mesocricetus auratus) by depletion of phenylalanine and
      tyrosine in the diet and by inhibition of tyrosinase. Brief report.

PMID- 4368640
TI  - Effects of acetylcholine on incorporation of (14C)glucose into
      phosphatidylinositol and on phosphatidylinositol breakdown in subcellular
      fractions from cerebral cortex.

PMID- 4368642
TI  - Effects of alcohols on the autoxidation of cytochrome c-1.

PMID- 4368643
TI  - Effects of cyclic adenosine nucleotides on fluid absorption by different segments
      of proximal tubule.

PMID- 4368641
TI  - Effects of adrenalectomy and corticosterone on thyroid weight of goitrogen
      treated rats. Role of adrenal-corticoids in the insulin increase of goitre
      weight.

PMID- 4368644
TI  - Effects of demethylchlortetracycline on cellular action of antidiuretic hormone
      in vitro.

PMID- 4368645
TI  - Effects of dopamine-like drugs on rat striatal adenyl cyclase have implications
      for CNS dopamine receptor topography.

PMID- 4368646
TI  - Effects of ethanol, methanol and different antibiotics on the ATPase and GTPase
      activities associated with B. stearothermophilus 5 S RNS- protein complex.

PMID- 4368647
TI  - Effects of halothane and other anesthetic agents on the concentrations of rat
      liver metabolites in vivo.

PMID- 4368648
TI  - Effects of hypophysectomy and TSH replacement on the ultrastructural localization
      of thyroperoxidase.

PMID- 4368650
TI  - Effects of ovine luteinizing hormone and porcine adrenocorticotropin on
      maturation of oocytes of the catfish, Heteropneustes fossilis (Bloch), in ovary
      interrenal coculture.

PMID- 4368649
TI  - Effects of morphine on kinetics of 14C-dopamine in rat striatal slices.

PMID- 4368651
TI  - Effects of photo-oxidation on the catalytic and regulatory properties of citrate
      synthase from Acinetobacter lwoffi.

PMID- 4368652
TI  - Effects of pyrazole on ethanol-induced changes in hepatic triglyceride and
      glycerol-1-phosphate contents and on esterified and non-esterified fatty acids in
      the blood.

PMID- 4368653
TI  - Effects of succinyl-con A on the growth of normal and transformed cells.

PMID- 4368654
TI  - Effects of theophylline and propranolol on acetylcholine-induced release of
      adrenal medullary catecholamines.

PMID- 4368655
TI  - Effects of thyroid hormone deficiency on cyclic adenosine 3':5'-monophosphate and
      control of lipolysis in fat cells.

PMID- 4368656
TI  - Effects of ACTH on the sleep of normal subjects and patients with Addison's
      disease.

PMID- 4368657
TI  - Electro-oculography: a clinical normal case series.

PMID- 4368659
TI  - Electrocorticogram and behavioral correlates during the development of chronic
      cobalt experimental epilepsy in the rat.

PMID- 4368660
TI  - Electron microscopic observations on postnatal development of the X zone in mouse
      adrenal cortex.

PMID- 4368658
TI  - Electro-optical system for monitoring activity of heart cells in culture:
      application to the study of several drugs and scorpion toxins.

PMID- 4368662
TI  - Electron microscopy as a supplement in the diagnosis of glomus jugulare tumor.

PMID- 4368661
TI  - Electron microscopical studies of the acetylcholinesterase-positive and -negative
      nerve fibres in the ciliary body of the albino rat.

PMID- 4368663
TI  - Electron microscopy of the lung in experimental Toxocara canis infection.

PMID- 4368665
TI  - Electron paramagnetic resonance study of the interaction of a spin-labeled analog
      of adenosine diphosphoribose with paramagnetic cobalt(II) liver alcohol
      dehydrogenase.

PMID- 4368664
TI  - Electron microscopy of young Candida albicans chlamydospores.
AB  - One- to three-day-old cultures of Candida albicans bearing chlamydospores were
      grown and harvested by a special technique, free of agar, and prepared for
      ultramicrotomy and electron microscopy. These young chlamydospores exhibited a
      subcellular structure similar to that of the yeast phase, e.g., cytoplasmic
      membrane, ribosomes, and mitochondria. Other structural characteristics unique to
      chlamydospores were a very thick, layered cell wall, the outer layer of which was
      continuous with the outer layer of the suspensor cell wall and was covered by
      hair-like projections; membrane bound organelles; and large lipoid inclusions.
      Only young chlamydospores less than 3 to 4 days old exhibited these
      ultrastructural characteristics.

PMID- 4368666
TI  - Electron spin resonance spectrometry on the whole mouse in vivo: a 100 MHZ
      spectrometer.

PMID- 4368668
TI  - Electron spin resonance studies on diol dehydrase. 3. Rapid kinetic studies on
      the rate of formation of radicals in the reaction with propanediol.

PMID- 4368667
TI  - Electron spin resonance studies of free radicals in solution. 3. pH dependence of
      thiyl free radical of cysteine.

PMID- 4368669
TI  - Electron transport phosphorylation.

PMID- 4368670
TI  - Electron-paramagnetic-resonance studies on nitrogenase. Investigation of the
      oxidation-reduction behaviour of azoferredoxin and molybdoferredoxin with
      potentiometric and rapid-freeze techniques.

PMID- 4368671
TI  - Electron-paramagnetic-resonance study of manganese ions bound to concanavalin A.

PMID- 4368672
TI  - Elongation factor T-dependent GTP hydrolysis: dissociation from aminoacyl-tRNA
      binding.

PMID- 4368673
TI  - Elongation factor 2. Amino acid sequence at the site of adenosine diphosphate
      ribosylation.

PMID- 4368676
TI  - Endemic goitre and thyroid function in Central Africa.

PMID- 4368675
TI  - Encephalomyocarditis virus infection of mouse plasmacytoma cells. II. Effect on
      host RNA synthesis and RNA polymerases.
AB  - The effect of encephalomyocarditis virus infection of MOPC 460 mouse plasmacytoma
      cells on host RNA synthesis and RNA polymerases was investigated. Consistent with
      work performed in other virus host systems, rates of RNA synthesis appeared to be
      inhibited in infected cells, whereas RNA degradation appeared normal. These
      results were further extended with isolated nuclei, in which distinct RNA
      polymerase activities could be studied under conditions where problems with RNA
      turnover and endogenous nucleotide pool sizes were insignificant. Endogenous
      nuclear RNA polymerase II activity was inhibited early postinfection and at 1 to
      2 h prior to endogenous RNA polymerase I plus III activity. However, the
      solubilized enzymes were fully active with exogenous DNA as template. In fact,
      the levels of RNA polymerases I, II, and III, isolated from infected cells and
      nuclei, were indistinguishable from levels in uninfected cells and nuclei at each
      stage of their partial purification procedure. The chromatographic properties of
      the enzymes on DEAE-Sephadex were also unaltered. Furthermore, the RNA synthetic
      activity of these isolated enyzmes, or of nuclei isolated from uninfected cells,
      was resistant to extracts of nuclei or of cytoplasmic fractions from infected
      cells. These results are discussed in terms of a possible inhibition of RNA
      synthesis in vivo at the level of transcription initiation.

PMID- 4368674
TI  - Encephalomyocarditis virus infection of mouse plasmacytoma cells. I. Inhibition
      of cellular protein synthesis.
AB  - Mouse plasmacytoma ascites tumor cells (MOPC 460) were efficiently infected with
      encephalomyocarditis virus. Inhibition of host protein synthesis was evident
      after 2 h and complete by 4 h postinfection. The mechanism by which virus
      infection results in inhibition of host cell protein synthesis was studied in
      vitro. Cell-free protein-synthesizing systems, prepared from uninfected and
      infected cells, were found to be equally active with respect to their abilities
      to translate cellular and viral mRNAs. The plasmacytoma cell-free system was also
      shown to be insensitive to the addition of double-stranded viral RNA. Host
      cellular mRNA was isolated from uninfected and infected cells. No difference in
      the amount or size distribution of the mRNA was detected. However, the mRNA from
      infected cells was translated only 46 to 49% as actively as that from uninfected
      cells. mRNA isolated from cells in which initiation of protein synthesis was
      inhibited with pactamycin was similarly inactivated. Simultaneous addition of
      viral RNA and cellular mRNA to the plasmacytoma cell-free system resulted in a
      complete suppression of the translation of the cellular message, whereas viral
      RNA was translated normally.

PMID- 4368677
TI  - Endocrine functions during adaptation to stress.

PMID- 4368678
TI  - Endocrine tumors of the pancreas associated with elevated urinary serotonin
      excretion.

PMID- 4368679
TI  - Enhanced interferon response to murine leukemia virus by ascorbic acid.
AB  - BALB/cJ mice, on an ad libitum regimen of 250 mg% l-ascorbate in their drinking
      water, displayed augmented levels of circulating interferon after stimulation
      with murine leukemia virus.

PMID- 4368681
TI  - Enhancement of radiation effects by heating of the tumor.

PMID- 4368680
TI  - Enhancement of radiation effects by chemotherapy.

PMID- 4368682
TI  - Enhancement of DNA synthesis of mouse myelogenous cells by cyclic adenosine 3',5'
      monophosphate (cAMP).

PMID- 4368683
TI  - Enterovirus type 70: the etiologic agent of pandemic acute haemorrhagic
      conjunctivitis.
AB  - A new enterovirus, now classified as enterovirus type 70, was isolated from the
      conjunctiva of patients with acute haemorrhagic conjunctivitis during the 1971
      epidemics that occurred in Japan, Singapore, and Morocco. These epidemics were
      parts of a pandemic involving Africa (Algeria, Ghana, Morocco, Nigeria, and
      Tunisia), Asia (Cambodia, China (Province of Taiwan), Hong Kong, India,
      Indonesia, Japan, Malaysia, the Philippines, Singapore, and Thailand), and
      England during 1969-71. A representative strain from each of the three epidemic
      areas was studied cooperatively. The strains exhibited the physicochemical
      characteristics of enteroviruses. Cross-neutralization tests showed that these
      viruses were distinct from all known human enterovirus immunotypes, but that they
      were antigenically closely related. The human origin of the viruses was
      demonstrated by the appearance of homologous neutralizing antibodies during
      convalescence in patients with acute haemorrhagic conjunctivitis.

PMID- 4368684
TI  - Environmental mutagen testing in Escherichia coli and phage lambda.

PMID- 4368685
TI  - Enzymatic acylation of 1-alkyl-, 1-alkenyl- and 1-acyl glycero-3
      phosphorylethanolamine in developing rat brain.

PMID- 4368686
TI  - Enzymatic formation of uridine diphosphate N-acetyl-D-mannosaminuronic acid.

PMID- 4368687
TI  - Enzymatic methods for sequence analysis applied to DNA restriction and
      methylation sites.

PMID- 4368688
TI  - Epidermal growth factor: effects of androgens and adrenergic agents.

PMID- 4368689
TI  - Epinephrine binding by rat liver plasma membranes: effect of guanyl nucleotides.

PMID- 4368690
TI  - Epstein-Barr virus and heterophile antibodies in infectious mononucleosis.

PMID- 4368691
TI  - Epstein-Barr virus specific diagnostic tests in infectious mononucleosis.

PMID- 4368693
TI  - Erythrocyte membrane vacuole formation in hereditary spherocytosis.

PMID- 4368692
TI  - Equilibrium kinetic study of bovine liver glutamate dehydrogenase at high pH.

PMID- 4368694
TI  - Escape of intestinal resistance vessels to angiotensin II.

PMID- 4368695
TI  - Escape of TA3 tumors from allogeneic immune rejection: theory and experiments.

PMID- 4368697
TI  - Estradiol receptors: a new evaluation.

PMID- 4368696
TI  - Establishment of a tetraploid, immunoglobulin-producing cell line from the
      hybridization of two human lymphocyte lines.
AB  - We here report the establishment of a seemingly permanent hybrid cell line formed
      by fusion of the cells of two biochemically mutant human lymphocyte lines. One
      parental line (UM-1-6TGr) was deficient in hypoxanthine-guanine phosphoribosyl
      transferase (IMP: pyrophosphate phosphoribosyltransferase, EC 2.4.2.8), and had
      two marker chromosomes. The second parental line (UM-21-5) was a clonal
      derivative of a citrullinemic lymphocyte line, and was, like the line of origin,
      dificient in argininosuccinic acid synthetase [(L)-Citrulline: (L)-aspartate
      ligase (AMP-forming), EC 6.3.4.5]. This line also had a marker chromosome, which
      was a B5 with a very prominent secondary constriction. After trypsinization of
      both parental lines, followed by addition to the fusion mixture of beta
      propiolactone-inactivated Sendai virus, the cells were placed in a doubly
      selective medium (hypoxanthine-aminopterin-thymidine-containing medium in which
      the arginine was replaced with citrulline) to prevent the proliferation of the
      mutant parents. Under selective conditions, 97-99% of cells were found to be
      tetraploid, containing the three marker chromosomes; and the specific activities
      of the hybrid line transferase and synthetase were intermediate between normal
      and mutant line values. Furthermore, the UM-1-6TGr and UM-21-5 lines were
      producers of gamma and mu heavy chains of immunoglobulin, and of kappa light
      chains, as determined by immunodiffusion and immunofluorescence, and the hybrid
      line continued to synthesize and to secrete detectable levels of these same
      immunoglobulins. These studies demonstrate the genic and cytogenetic stability of
      this hybridized lymphocyte cell line, and prove that hybridization per se does
      not extinguish the activity of either the regulatory of structural genes involved
      in immunoglobulin synthesis.

PMID- 4368698
TI  - Estrogen binding in the rat and human.

PMID- 4368699
TI  - Estrogen receptor transformation and nuclear RNA synthesis.

PMID- 4368700
TI  - Estrogenic profile on a water-soluble estrogen, estrazinol hydrobromide.

PMID- 4368702
TI  - Evaluation of physical maturity in adolescent mentally retarded boys.

PMID- 4368701
TI  - Ethanol-induced inhibition of human intestinal enzyme activities: reversal by
      folic acid.

PMID- 4368703
TI  - Evidence against formation of a pyrophosphoryl enzyme intermediate in the
      phosphoribosylpyrophosphate synthetase reaction.

PMID- 4368704
TI  - Evidence for a guanosine-3':5'-monophosphate-binding protein from rat cerebellum.

PMID- 4368706
TI  - Evidence for a role of the Epstein-Barr virus in the etiology of human lymphoma.

PMID- 4368705
TI  - Evidence for a role for protein phosphorylation in synaptic function in the
      cerebral cortex mediated through a beta noradrenergic receptor.

PMID- 4368707
TI  - Evidence for cooperative binding of Triton X-100 to bovine serum albumin.

PMID- 4368708
TI  - Evolutionary clock: the rate of evolution of rattlesnake cytochrome c.

PMID- 4368709
TI  - Existence of two pools of prostaglandins during stimulation of the thyroid by
      TSH.

PMID- 4368711
TI  - Experimental transmission of equine adenovirus in Arabian and non-Arabian foals.

PMID- 4368710
TI  - Experimental autoallergic parotitis.

PMID- 4368712
TI  - Extraction, partial purification and characterization of 'the insoluble estrogen
      receptor' from chick liver nuclei.

PMID- 4368713
TI  - EM49: a new polypeptide antibiotic active against cell membranes.

PMID- 4368714
TI  - Facial muscle tonus during REM and NREM sleep.

PMID- 4368715
TI  - Facilitation by adenosine of the action of insulin on the accumulation of
      adenosine 3':5'-monophosphate, lipolysis, and glucose oxidation in isolated fat
      cells.

PMID- 4368716
TI  - Factors affecting the saturation assay of cyclic AMP in biological systems.

PMID- 4368717
TI  - Factors associated with treatment success in lithium carbonate prophylaxis.
      Report of the Veterans Administration and National Institute of Mental Health
      collaborative study group.

PMID- 4368718
TI  - Failure of pentagastrin to stimulate cyclic AMP accumulation in human gastric
      mucosa.

PMID- 4368719
TI  - False negative and prozone reactions in tests for antibodies to Epstein-Barr
      virus-associated nuclear antigen.

PMID- 4368720
TI  - Familial homozygous hypobetalipoproteinemia.

PMID- 4368721
TI  - Fatal adenovirus pneumonia in a young adult associated with ADV-7 vaccine
      administered 15 days earlier.

PMID- 4368722
TI  - Fatty acid composition of the major lipid classes of very low density
      lipoproteins and of plasma in rats poisoned with carbon tetrachloride.

PMID- 4368723
TI  - Fc binding of IgG to skeletal muscle tissue.

PMID- 4368724
TI  - Feed preferences of adult male Dutch rabbits.

PMID- 4368725
TI  - Feeding in ciliated protozoa. I. Pharyngeal disks in Euplotes: a source of
      membrane for food vacuole formation?

PMID- 4368726
TI  - Fibrinolysis associated with oncogenic transformation. Morphological correlates.

PMID- 4368727
TI  - Fibrinolysis associated with oncogenic transformation. Partial purification and
      characterization of the cell factor, a plasminogen activator.

PMID- 4368728
TI  - Field nutrition survey of Nigerian children in Ivory Coast refugee camps.

PMID- 4368730
TI  - First night effect revisited: a clinical note.

PMID- 4368729
TI  - Filtered air-positive pressure rearing of broiler chickens.

PMID- 4368731
TI  - Flagyl and reduced nicotinamide adenine dinucleotide.

PMID- 4368732
TI  - Fluorescence studies of cytochrome c1 and a cytochrome c1-cytochrome c complex.

PMID- 4368733
TI  - Function and interaction of on and off transients in vision. II. Neurophysiology.

PMID- 4368734
TI  - Functional organization of the vestibular input to ocular motoneurons of the
      frog.

PMID- 4368735
TI  - Functional similarity of yeast and mammalian adenosine 3',5'-monophosphate
      dependent protein kinases.

PMID- 4368736
TI  - Further analysis of the resistance of a colony of rats to dextran.

PMID- 4368737
TI  - Further evidence for the heterogeneity of liver lysosomes.

PMID- 4368739
TI  - Gas gangrene in a greyhound.

PMID- 4368738
TI  - Further studies on rat mast cell degranulation by IgE-anti-IgE and the inhibitory
      effect of drugs related to cAMP.

PMID- 4368740
TI  - General anesthesia for surgery in the infant pigtail monkey, Macaca nemestrina.

PMID- 4368743
TI  - Genital herpesvirus infection in pregnancy.

PMID- 4368742
TI  - Genetic counselling in retinoblastoma.

PMID- 4368741
TI  - Genetic blood markers and anthropometry of the populations in Aswan Governorate,
      Egypt.

PMID- 4368744
TI  - Geriatrics. Intermediate care facilities standards.

PMID- 4368745
TI  - Glucose oxidation in alveolar macrophages: pharmacologic features.

PMID- 4368747
TI  - Glycosyltransferases in canine respiratory tissue. Alterations in an
      experimentally induced hypersecretory state.

PMID- 4368746
TI  - Glycerol metabolism in Bacillus subtilis: gene-enzyme relationships.
AB  - Bacillus subtilis mutants unable to catabolize glycerol (Glp mutants) were
      isolated and mapped. The location of the mutations on the chromosome was
      determined by a density transfer technique and confirmed by PBS1 transduction and
      transformation. The different mutations were ordered relative to each other.
      Mutations rendering the cells glycerol auxotrophic were also mapped and found not
      to be linked to the Glp mutations.

PMID- 4368748
TI  - Golgi function and cell wall formation in the Conjugales.

PMID- 4368752
TI  - Goniotomy in congenital glaucoma.

PMID- 4368751
TI  - Gonadotropin receptors in rat ovarian tissue. II. Subcellular localization of LH
      binding sites by electron microscopic radioautography.

PMID- 4368750
TI  - Gonadotropin receptors in rat ovarian tissue. I. Localization of LH binding sites
      by fractionation of subcellular organelles.

PMID- 4368749
TI  - Gonadal hormones and triglycerides.

PMID- 4368753
TI  - Granular cell myoblastoma located in the floor of the mouth.

PMID- 4368754
TI  - Granular cell myoblastoma of the head and neck.

PMID- 4368755
TI  - Granular cell tumor (myoblastoma) of the bladder.

PMID- 4368756
TI  - Granulosa cell maturation in the rat: increased binding of human chorionic
      gonadotropin following treatment with follicle-stimulating hormone in vivo.

PMID- 4368757
TI  - Growth of mouse hepatitis and other indigenous mouse viruses in tracheal organ
      cultures.

PMID- 4368758
TI  - Guinea pig insulin. II. Biological activity.

PMID- 4368759
TI  - Haem ligands of the ferricytochrome c of Ustilago sphaerogena.
AB  - The mammalian-type cytochrome c of the basidiomycete Ustilago sphaerogena
      contains in a single polypeptide chain of 107 residues, two histidine residues
      located at positions 18 and 33, and one methionine residue situated at position
      80 (Bitar et al., 1972). The reaction of Ustilago ferricytochrome c with
      bromoacetate at neutral pH resulted in the modification of histidine-33, but not
      of histidine-18 or of the invariant methionine residue. The activities of
      Ustilago cytochrome c with mitochondrial cytochrome c oxidase and with NADH
      cytochrome c reductase were unaltered by the modification. The equilibrium
      constants for the formation of low-spin complexes of the ferrihaem octapeptide of
      horse cytochrome c (residues 14-21, including the haem bound covalently to
      cysteines 14 and 17) with imidazole, N(2)-acetylhistidine and monocarboxymethyl
      derivatives of N(2)-acetylhistidine were determined spectrophotometrically.
      Alkylation of the imidazole side-chain group of N(2)-acetylhistidine resulted in
      a marked decrease in its ability to form low-spin ferrihaem complexes. These
      results indicate that in Ustilago ferricytochrome c in solution histidine-33 is
      not involved in the central co-ordination complex. Since side-chain groups of
      residues other than histidine and methionine do not appear to be involved in the
      central complexes of other mammalian-type cytochromes c (Hettinger & Harbury,
      1964, 1965; Myer & Harbury, 1965) it is likely that in Ustilago ferricytochrome c
      in solution at neutral pH, the side-chain groups of histidine-18 and methionine
      80 are involved in the central co-ordination complex. The latter is stable over
      the pH range 2.6-8.4.

PMID- 4368761
TI  - Health care cooperation at Aquarius Festival.

PMID- 4368760
TI  - Hapten-specific tolerance in mice. II. Adoptive transfer studies and evidence for
      unresponsiveness in the B cells.

PMID- 4368762
TI  - Heat denaturation of D-glyceraldehyde-3-phosphate dehydrogenase holoenzyme.

PMID- 4368763
TI  - Helix-coil transition and conformational studies of nucleoprotein: poly(L
      arginine)- and poly(L-arginine87, L-ornithine13)-DNA complexes. II. Circular
      dichroism.

PMID- 4368764
TI  - Hematological and serological effects of Rauscher leukemia virus and Epstein-Barr
      virus on immunosuppressed newborn subhuman primates.

PMID- 4368765
TI  - Heme proteins: hemoglobin.

PMID- 4368766
TI  - Hepatic microsomal membrane: activation of glucose-6-phosphatase.

PMID- 4368768
TI  - Herpes nodules in the lung of the African elephant (Loxodonta africana
      (Blumebach, 1792)).

PMID- 4368767
TI  - Hepatoma associated with ulcerative colitis: Report of a case.

PMID- 4368769
TI  - Herpesviruses and cancer.

PMID- 4368770
TI  - Herring bodies reexamined: an ultrastructural experimental investigation of the
      rat neural lobe.

PMID- 4368771
TI  - High reactivity of kidney preparations from man, pig, beef, dog and rat for
      carbamyl phosphate hydrolysis.

PMID- 4368772
TI  - Histidine residues and the enzyme activity of pig heart supernatant malate
      dehydrogenase.
AB  - 1. Supernatant pig heart malate dehydrogenase is completely inhibited by reaction
      with diethyl pyrocarbonate at pH6.5, when 0.58+/-0.1 residue of
      ethoxycarbonylhistidine is formed per NADH-binding site. 2. Oxaloacetate and
      hydroxymalonate protect the enzyme from inhibition in the absence of coenzyme. 3.
      Limited ethoxycarbonylation does not alter the binding of NADH to the enzyme but
      prevents the enzyme-NADH complex from interacting with hydroxymalonate in a
      ternary complex.

PMID- 4368773
TI  - Histochemical findings on sodium-potassium activated adenosine triphosphatase
      (NaK-ATPase) activity in the cornea.

PMID- 4368774
TI  - Histochemical studies of hepatic enzymes in dogs subjected to lobar bile duct
      obstruction.

PMID- 4368775
TI  - Histochemistry and ultrastructure of atypical myoclonus body (type II).

PMID- 4368776
TI  - Histologic and histochemical studies on C cells in the thyroid gland in white
      rats under conditions of chronic hypercalcemia induced with vitamin D3.

PMID- 4368778
TI  - Hormonal effects on mammary cytology.

PMID- 4368777
TI  - Hormonal control of lipolysis.

PMID- 4368780
TI  - Human ecthyma contagiosum (orf) in the Faroe islands. An epidemiological and
      electron microscopical study.

PMID- 4368779
TI  - Hormone-receptor interactions with the genome of eucaryotic target cells.

PMID- 4368781
TI  - Human N-acetyl-beta-hexosaminidases: hydrolysis of N, N' diacetylchitobiose by a
      low molecular weight enzyme.

PMID- 4368782
TI  - Hypoglycemia in infancy caused by beta cell nesidioblastosis.

PMID- 4368783
TI  - Iatrogenic disorders in epilepsy.

PMID- 4368785
TI  - Identification of missense mutants by amino acid replacements in iso-1-cytochrome
      c from yeast.

PMID- 4368784
TI  - Identification of bile acids as their derivatives by 100 MHZ PMR spectroscopy.

PMID- 4368786
TI  - Identity of a newly isolated human polyomavirus from a patient with progressive
      multifocal leucoencephalopathy.
AB  - Isolation of a strain of polyomavirus, designated COL, from the brain of a
      patient with progressive multifocal leucoencephalopathy is described. The COL
      strain is antigenically similar to JC polyomavirus, previously isolated from a
      brain affected by progressive multifocal leucoencephalopathy and is unrelated to
      BK, another human polyomavirus isolated from urine. Immunological cross testing
      of viruses in the Polyomavirus genus shows that there are at least six antigenic
      types in this group.

PMID- 4368787
TI  - Immunity in viral and rickettsial diseases. Round table conference.

PMID- 4368788
TI  - Immunocytes and leukemia virus infection: effects on bone marrow and thymus cell
      responses and interactions.

PMID- 4368790
TI  - Immunofluorescence and elution studies in tetraparental NZB forms and is formed
      from CFW chimaeras and graft-versus-host diseased NZB.

PMID- 4368791
TI  - Immunologic study of an oncornavirus isolated from a human cancer cell line.

PMID- 4368789
TI  - Immunodeficiency states.

PMID- 4368792
TI  - Immunological cross-reactions between two low-molecular-weight polypeptides from
      a murine type C virus.
AB  - Two low-molecular-weight type-specific virion polypeptides from the Kirsten
      strain of Murine leukemia virus, polypeptides p10 and p12, are immunologically
      related by radioimmunoassay competition techniques.

PMID- 4368795
TI  - Implications of selection for high and low adrenal response to stress.

PMID- 4368796
TI  - Important events in photosynthesis.

PMID- 4368794
TI  - Immunospecificity of chromatin nonhistone protein--DNA complexes in normal and
      neoplastic growth.

PMID- 4368793
TI  - Immunological studies of the protein moieties of human plasma very low-density
      and low-density lipoproteins.

PMID- 4368797
TI  - Improved prognosis of infants mechanically ventilated for hyaline membrane
      disease.

PMID- 4368798
TI  - In vitro labelling of childhood cancers with tritiated thymidine.

PMID- 4368799
TI  - In vitro synthesis of proteins by membrane-bound polyribosomes from vesicular
      stomatitis virus-infected HeLa cells.
AB  - Membrane-bound polysomes from vesicular stomatitis virus (VSV)-infected HeLa
      cells synthesize predominantly three proteins in an in vitro protein synthesizing
      system. These three proteins have different molecular weights than the viral
      structural proteins, i.e., 115,000, 88,000, and 72,000. Addition of preincubated
      L or HeLa cell S10 or HeLa cell crude initiation factors stimulates amino acid
      incorporation and, furthermore, alters the pattern of proteins synthesized.
      Stimulated membrane-bound polysomes synthesize predominantly viral protein G and
      lesser amounts of N, NS, and M. In vitro synthesized proteins G and N are very
      similar to virion proteins G and N based on analysis of tryptic methionine
      labeled peptides. Most methionine-labeled tryptic peptides of virion G protein
      contain no carbohydrate moieties, since about 90% of sugar-labeled peptides co
      chromatograph with only about 10% of methionine-labeled peptides. Sucrose
      gradient analysis of the labeled RNA present in VSV-infected membrane-bound
      polysomes reveals a relative enrichment in a class of viral RNA sedimenting
      slightly faster than the total population of the 13 to 15S mRNA, as compared to a
      VSV-infected crude cytoplasmic extract. A number of proteins, other than the
      viral structural proteins, are synthesized in the cytoplasm of five lines of VSV
      infected cells. One of these proteins has the same molecular weight as the major
      in vitro synthesized protein, P(88). In vitro synthesized protein P(88) does not
      appear to be a precursor of viral structural proteins G, N, or M based on pulse
      chase experiments and tryptic peptide mapping. Nonstimulated membrane-bound
      polysomes from uninfected HeLa cells synthesize the same size distribution of
      proteins as nonstimulated VSV-infected membrane-bound polysomes.

PMID- 4368800
TI  - In vitro synthesis of structural proteins of Semliki Forest virus directed by
      isolated 26 S RNA from infected cells.

PMID- 4368802
TI  - In vivo and in vitro properties of a temperature sensitive mutant of infectious
      bovine Rhinotracheitis virus.

PMID- 4368801
TI  - In vitro synthesis of Rous sarcoma virus-specific RNA is catalyzed by a DNA
      dependent RNA polymerase.
AB  - Synthesis of Rous sarcoma virus RNA was examined in vitro with a new assay for
      radioactive virus-specific RNA. Nuclei from infected and uninfected cells were
      incubated with ribonucleoside [alpha-(32)P]triphosphates, Mn(++), Mg(++) and
      (NH(4))(2)SO(4). Incorporation into total and viral RNA proceeded with similar
      kinetics for up to 25 min at 37 degrees . About 0.5% of the RNA synthesized by
      the infected system was scored as virus-specific, compared to 0.03% of the RNA
      from the uninfected system and 0.005% of the RNA synthesized by monkey kidney
      cell nuclei. Preincubation with DNase or actinomycin D completely suppressed
      total and virus-specific RNA synthesis. alpha-Amanitin, a specific inhibitor of
      eukaryotic RNA polymerase II, completely inhibited virus-specific RNA synthesis,
      while reducing total RNA synthesis by only 50%. We conclude that tumor virus
      specific RNA is synthesized on a DNA template, most probably by the host's RNA
      polymerase II.

PMID- 4368804
TI  - Inactivation of trypsinogen by methane sulfonyl fluoride.

PMID- 4368805
TI  - Incidence of clostridia in meat products.

PMID- 4368803
TI  - In vivo effects of pancreozymin, secretin, vasoactive intestinal polypeptide and
      pilocarpine on the levels of cyclic AMP and cyclic GMP in the rat pancreas.

PMID- 4368806
TI  - Incidence of postoperative complications in patients subjected to surgery under
      steroid cover.

PMID- 4368808
TI  - Increase of serum free thyroxine following the administration of thiocyanate and
      other anions in vivo and in vitro.

PMID- 4368807
TI  - Increase in hepatic NAD level--its effect on the redox state and on ethanol and
      acetaldehyde metabolism.

PMID- 4368809
TI  - Increased binding of calcitonin to renal receptors in parathyroidectomized rats.

PMID- 4368810
TI  - Increased paradoxical sleep in mice during acquisition of a shock avoidance task.

PMID- 4368811
TI  - Increased thermal stability of chromatin containing 5-bromodeoxyuridine
      substituted DNA.
AB  - The replacement of thymidine by 5-bromodeoxyuridine in DNA leads to a greatly
      enhanced stability of chromatin from hepatoma tissue culture or embryonic rat
      pancreas, as measured by thermal chromatography on hydroxylapatite. The increased
      stability is directly correlated with the degree of bromodeoxyuridine
      substitution. On the other hand, the incorporation of bromodeoxyuridine into DNA
      results in a modest stabilization of purified DNA. Substitution of nucleotide
      also alters slightly the hyperchromicity profile generated during the thermal
      denaturation of purified DNA and chromatin. The observed changes can best be
      explained by an altered interaction between the bromodeoxyuridine-DNA and other
      chromatin components, presumably proteins. These results suggests that the
      selective effects of bromodeoxyuridine on cytodifferentiation may be due to an
      increased affinity of regulatory proteins for bromodeoxyuridine-DNA.

PMID- 4368812
TI  - Increased PRPP synthetase activity in rapidly growing hepatomas.

PMID- 4368813
TI  - Increases in activities of aminoacyl-tRNA synthetases during cold-treatment of
      dormant pear embryo.

PMID- 4368814
TI  - Induction and inhibition of ovulation in the rat by intracerebral progesterone
      implants.

PMID- 4368815
TI  - Infectious tenosynovitis: serologic and histopathologic response after
      experimental infection with a Connecticut isolate.

PMID- 4368817
TI  - Influence of ligands on the coenzyme dissociation constants in octopine
      dehydrogenase.

PMID- 4368816
TI  - Inflammatory pseudotumor of the lung.

PMID- 4368818
TI  - Influence of NAD+ on development of mouse blastocysts in vitro.

PMID- 4368820
TI  - Inhibition effect of quinaldic acid on glucose-induced insulin release from
      isolated Langerhans islets of the rat.

PMID- 4368819
TI  - Inhibition by interferon of SV40 tumor antigen formation in cells injected with
      SV40 cRNA transcribed in vitro.

PMID- 4368821
TI  - Inhibition of a vesicular stomatitis virus mutant by rifampin.
AB  - Rifampin reversibly inhibits the intracellular replication of a VSV mutant,
      whereas a revertant variant selected from this viral population, as well as the
      wild strain, are not affected by this drug. Rifampin inhibits transcriptase
      activity of the sensitive mutant only and, consequently, total viral RNA
      synthesis decreases significantly in the cells.

PMID- 4368822
TI  - Inhibition of phagocytosis and plasma membrane mobility of the cultivated
      macrophage by cytochalasin B. Role of subplasmalemmal microfilaments.
AB  - Functional and morphologic effects of cytochalasin B on the cultivated macrophage
      were examined to determine the basis for plasma membrane movements of the type
      required for endocytosis and/or spreading on a substratum. Inhibition of
      phagocytosis and changes in cell shape by cytochalasin B exhibited nearly
      identical dose-response curves requiring 2-5 x 10(-6) M and 1-2 x 10(-5) M
      cytochalasin B to inhibit these functions by 50% and 100%, respectively. In
      contrast, hexose transport was ten times more sensitive to the drug requiring 2-3
      x 10(-7) M cytochalasin B to achieve 50% inhibition of 2-deoxyglucose uptake.
      Inhibition of phagocytosis and changes in cell shape could not be explained
      solely by drug effects on hexose transport. Analysis of serial thin sections
      showed that cytochalasin B doses inhibitory for hexose transport had no effect on
      distribution or organization of either of the two subplasmalemmal microfilament
      types. However, cytochalasin B concentrations (2.0 x 10(-5) M) that inhibited
      phagocytosis and altered cell shape disorganized and/or disrupted oriented
      bundles of 40-50-A subplasmalemmal microfilaments, but had no effect on the
      microfilamentous network. Comparative dose-response studies showing positive
      correlations among cytochalasin B effects on phagocytosis, changes in cell shape,
      and alterations in oriented subplasmalemmal microfilament bundles provide
      additional support for the hypothesis that microfilamentous structures play a
      role in translocation of plasma membrane required for endocytosis and cell
      motility.

PMID- 4368824
TI  - Inhibition of AMV DNA polymerase by polyriboadenylic acid containing epsilon
      adenosine residues.

PMID- 4368823
TI  - Inhibition of rat liver Ca2+, Mg2+-dependent endonuclease activity by
      nicotinamide adenine dinucleotide and poly (adenosine diphosphate ribose)
      synthetase.

PMID- 4368825
TI  - Inhibition of 3',5'-nucleotide phosphodiesterase in guinea pig cerebral cortical
      slices.

PMID- 4368826
TI  - Inhibitory effects of central hypertensive activity of angiotensin I and II by 1
      sar-8-ala-angiotensin II (saralasin acetate).

PMID- 4368827
TI  - Inhibitory effects of 2-thiouracil and 2-thiouracil metabolites on enzymes
      involved in pyrimidine nucleotide biosynthesis.

PMID- 4368828
TI  - Insulin secretion: multifactorial regulation for a single process of release. The
      Minkowski award lecture delivered on September 7, 1972 before the European
      Association for the study of Diabetes at Madrid, Spain.

PMID- 4368829
TI  - Interaction of human serum high density lipoproteins with triglycerides in vitro.

PMID- 4368830
TI  - Interaction of phalloidin with actin.
AB  - Phalloidin, a toxic bicyclic peptide of rapid action from the toadstool, Amanita
      phalloides, gives rise to polymerization of G-actin to filamentous structures (Ph
      actin) in a medium of low ionic strength. Ph-actin closely resembles the
      microfilaments found in liver membrane fractions (Ph-filaments) after in vivo or
      in vitro poisoning. Both phalloidin induced filaments are resistant to 0.6 M KI
      in contrast to F-actin, and become decorated by heavy meromyosin. After
      preincubation with cytochalasin B significantly fewer actin filaments are
      observed.

PMID- 4368831
TI  - Interactions of glucagon, gut glucagon, vasoactive intestinal polypeptide and
      secretin with liver and fat cell plasma membranes: binding to specific sites and
      stimulation of adenylate cyclase.

PMID- 4368832
TI  - Interactions of LH and hCG with testicular gonadotropin receptors.

PMID- 4368833
TI  - Interconversion of ampicillin and hetacillin in vitro.

PMID- 4368835
TI  - Intermolecular steric interactions and lipid chain fluidity in phospholipid
      multibilayers. A spin label study.

PMID- 4368836
TI  - Interstitial cell tumor of the testicle in rabbits: a report of two cases.

PMID- 4368834
TI  - Intermembrane electron transfer in mitochondrial and microsomal systems.

PMID- 4368837
TI  - Intestinal glycoproteins of germfree rats. 3. Characterization of a water-soluble
      glycoprotein fraction.

PMID- 4368838
TI  - Intracranial causes of headache.

PMID- 4368839
TI  - Intranuclear annulate lamellae in Ehrlich ascites tumour cells.

PMID- 4368840
TI  - Intranuclear concentration of lysosomal hydrolases in steroid target cells. Acute
      response to administration of gonadal hormones in vivo.

PMID- 4368841
TI  - Introduction of mouse L cell nucleus into heterologous mammalian cells.

PMID- 4368843
TI  - Investigation of recognition sites in valine tRNA I (Baker's yeast) by dissected
      molecule method.

PMID- 4368842
TI  - Investigation of a family with hypertrophic neuropathy resembling Roussy-Levy
      syndrome. Clinical, electrophysiologic, histologic, and biochemical studies.

PMID- 4368844
TI  - Investigations on the release of membrane-bound glyceraldehyde-3-phosphate
      dehydrogenase.

PMID- 4368846
TI  - Is cortisol metabolized as it dissociates from glucocorticoid receptors in thymus
      cells?

PMID- 4368845
TI  - Iontophoretic and autoradiographic studies on the role of proline in nervous
      transmission.

PMID- 4368847
TI  - Isolated hypoaldosteronism associated with idiopathic hypoparathyroidism.

PMID- 4368848
TI  - Isolation and characterization of plasma and smooth membranes of the marine
      diatom Nitzschia alba.

PMID- 4368849
TI  - Isolation and identification of infectious bursal disease virus in Lebanon.

PMID- 4368850
TI  - Isolation and partial characterization of a glycoprotein from bovine cortical
      bone.

PMID- 4368851
TI  - Isolation of a myelogenous leukemia-inducing virus from mice infected with the
      Friend virus complex.

PMID- 4368852
TI  - Japanese encephalitis vaccination in Thailand.

PMID- 4368853
TI  - Juvenile fibroma of antral origin.

PMID- 4368854
TI  - Juvenile GM1 gangliosidosis. Occurrence with absence of two beta-galactosidase
      components.

PMID- 4368855
TI  - Kinetic techniques for the investigation of amino acid: tRNA ligases (aminoacyl
      tRNA synthetases, amino acid activating enzymes).

PMID- 4368857
TI  - Klebsiella air sacculitis in the owl monkey (Aotus trivirgatus).

PMID- 4368856
TI  - Kinetics of aminoacyl-tRNA synthetases catalyzed ATP-PPi exchange.

PMID- 4368858
TI  - Laboratory aids in the diagnosis of tumors of the pancreas.

PMID- 4368859
TI  - Letter: Basal cell adenomas.

PMID- 4368860
TI  - Letter: Feline leukemia virus.

PMID- 4368862
TI  - Letter: On the possible role of cAMP in receptor dark adaptation.

PMID- 4368861
TI  - Letter: Letter: Nucleotide distribution in bacterial DNA's differing in G plus C
      content.

PMID- 4368863
TI  - Letter: Relief of pain in women with genital herpes.

PMID- 4368865
TI  - Levels of adenosine 3',5'-cyclic monophosphate in the cerebral cortex of aging
      rats.

PMID- 4368864
TI  - Leukocyte chemotaxis in vivo. II. Analysis of the selective inhibition of
      neutrophil or mononuclear cell accumulation.

PMID- 4368866
TI  - Lightly haptenated proteins induce IgM-deficient antibody responses.

PMID- 4368867
TI  - Linitis plastica carcinoma of the intestine: Report of four cases.

PMID- 4368868
TI  - Lipid acceptor in UDPglucuronic acid metabolism in rat liver microsomes.

PMID- 4368869
TI  - Lipid composition and cholesterol esterification in lymph.

PMID- 4368871
TI  - Lipids of potato tubers. 3. Effect of growth and storage on lipid content of the
      potato tuber.

PMID- 4368870
TI  - Lipid phase transitions and drug interactions.

PMID- 4368872
TI  - Lipoproteins and lipolytic plasma enzymes in a case of tangier disease.

PMID- 4368873
TI  - Lipotropic and adrenocorticotropic hormones. Biological activities of the
      carboxyl-modified hormones.

PMID- 4368874
TI  - Liver and spleen in rats after intravenous injection of Lipiodol Ultra-Fluide and
      99Tcm-sulphide colloid.

PMID- 4368876
TI  - Local immunity to avian infectious bronchitis in tracheal organ culture.

PMID- 4368875
TI  - Liver cirrhosis and hepatoma in rats induced by 3-benzylsydnone-4-acetamide.

PMID- 4368877
TI  - Long-term stimulatory effects of adenosine 3',5'-cyclic monophosphate on nuclear
      and cytoplasmic protein synthesis of rat hepatocytes in primary culture.

PMID- 4368878
TI  - Long-term survival after massive liver resection for hepatocellular carcinoma.

PMID- 4368879
TI  - Lumbar myelography and arachnoiditis.

PMID- 4368880
TI  - Luteinizing hormone receptors in luteinized rat ovaries.

PMID- 4368881
TI  - Lymphocyte tubuloreticular structures in lupus erythematosus. Correlation with
      disease activity.

PMID- 4368882
TI  - Lymphotic inclusions in I-cell disease.

PMID- 4368883
TI  - Lysosomal labilization: rapid, target-specific effect of ACTH.

PMID- 4368884
TI  - LH does not increase cyclic AMP in the thyroid.

PMID- 4368885
TI  - LH-RH interaction with the pituitary plasma membrane is affected by sex steroids.

PMID- 4368886
TI  - Magnetic resonance studies on glutamate dehydrogenase.

PMID- 4368887
TI  - Major or minor tranquilizers for relief of common symptoms of psychoneurosis?

PMID- 4368888
TI  - Malignant chemodectoma of the superior mediastinum with elevated urinary
      homovanillic acid.

PMID- 4368889
TI  - Malignant melanoma in a snake.

PMID- 4368890
TI  - Mass fragmentographic determination of eleven estrogens in the body fluids of
      pregnant and nonpregnant subjects.

PMID- 4368891
TI  - Mass spectra of trimethylsilyl ethers of 2H-labelled mono- and diglycerides.

PMID- 4368892
TI  - Maternal cardiovascular adjustments to pregnancy.

PMID- 4368893
TI  - Mathematics of hormone-receptor interaction. I. Basic principles.

PMID- 4368894
TI  - Measurement of the second and fourth components of rat complement.

PMID- 4368896
TI  - Mechanism of bacitracin action: a specific lipid-peptide interaction.

PMID- 4368895
TI  - Measurement of the sequence complexity of cloned Moloney murine leukemia virus 60
      to 70S RNA: evidence for a haploid genome.
AB  - The sequence complexity of the 60-70S RNA complex from Moloney murine leukemia
      virus (M-MuLV) was determined by measuring the annealing rate of radioactively
      labeled virus-specific DNA with M-MuLV 60-70S RNA in conditions of vast RNA
      excess. The M-MuLV RNA annealing rate, characterized by the quantity
      C(r)t((1/2)), was compared with the C(r)t((1/2)) values for annealing of
      poliovirus 35S RNA (2.6 x 10(6) molecular weight) with poliovirus-specific DNA
      and Sindbis virus 42S RNA (4.3 x 10(6) molecular weight) with Sindbis-specific
      DNA. M-MuLV-specific DNA was prepared in vitro by the endogenous DNA polymerase
      reaction of M-MuLV virions, and poliovirus and Sindbis virus DNAs were prepared
      by incubation of viral RNA and DNA polymerase purified from avian myeloblastosis
      virus and an oligo deoxynucleotide primer. The poliovirus and Sindbis virus DNAs
      were sedimented through alkaline sucrose gradients, and those portions of the DNA
      with sizes similar to the M-MuLV DNA were selected out for the annealing
      measurements. M-MuLV was cloned on NIH-3T3 cells because it appeared possible
      that the standard source of M-MuLV for these experiments was a mixture of
      viruses. The annealing measurements indicated a sequence complexity of
      approximately 9 x 10(6) daltons for the cloned M-MuLV 60-70S RNA when
      standardized to poliovirus and Sindbis virus RNAs. This value supports the
      hypothesis that each of the 35S RNA subunits of M-MuLV 60-70S RNA has a different
      base sequence.

PMID- 4368897
TI  - Mechanism of cell contact-dependent glycolipid synthesis: further studies with
      glycolipid-glass complex.

PMID- 4368898
TI  - Mechanism of control of skeletal-muscle contraction by dantrolene sodium.

PMID- 4368899
TI  - Mechanism of the interferon-induced block of mRNA translation in mouse L cells:
      reversal of the block by transfer RNA.

PMID- 4368900
TI  - Mechanisms of resistance of human acute leukaemia cells to cytosine arabinoside.

PMID- 4368901
TI  - Mechanisms of spasticity.

PMID- 4368902
TI  - Meiotic maturation of the mammalian oocyte in vitro: effect of dibutyryl cyclic
      AMP on protein synthesis.

PMID- 4368903
TI  - Melatonin: cellular effects on live stentors correlated with the inhibition of
      colchicine-binding to microtubule protein.

PMID- 4368904
TI  - Membrane filtration in the study of antimicrobial drugs.
AB  - A membrane filtration apparatus of the type employed in water bacteriology was
      used in the assessment of some antimicrobial drugs. Samples of liquid nutrient
      medium inoculated with a small number of bacteria, to which dilutions of a drug
      had been added before incubation and again later, were filtered and the membranes
      washed and incubated on solid medium. By this means differences between
      bacteriostatic and bactericidal action were clearly demonstrated. It was shown
      that staphylococci which had survived exposure to penicillin or gentamicin at
      levels below their minimum bactericidal concentrations remained fully responsive
      to the subsequent addition of more of the same drug, while those which had
      survived exposure to chloramphenicol or clindamycin were not significantly
      affected by further addition, so that neither of the latter two drugs was
      bactericidal against the strain of organism used. Bactericidal effects were also
      demonstrated by benzyl penicillin against Clostridium welchii and ampicillin
      against Escherichia coli.

PMID- 4368905
TI  - Membrane orientation in vesicles from Micrococcus lysodeikticus cells.

PMID- 4368906
TI  - Membrane receptors.

PMID- 4368907
TI  - Metabolic effects of N6-substituted adenosines in rats.

PMID- 4368908
TI  - Metabolic effects of 2-phenylethanol, 1,1-dimethylphenylethanol, periodate and
      succinic anhydride on intact yeast cells and on fermenting preparations from
      lyophilized yeast.

PMID- 4368909
TI  - Metabolism of progesterone in the chick oviduct: relation to the progesterone
      receptor and biological activity.

PMID- 4368910
TI  - Metabolites and the incorporation of L-leucine into rabbit insulin in vitro.

PMID- 4368911
TI  - Methaqualone: an irrational hypnotic.

PMID- 4368912
TI  - Methodological problems and clinical validity of an ACTH radioimmunoassay method
      applied to extracted plasma samples.

PMID- 4368913
TI  - Methoxyflurane anesthesia for Rana pipiens.

PMID- 4368914
TI  - Methylglyoxal formation during glucose catabolism by Pseudomonas saccharophila.
      Identification of methylglyoxal synthase.

PMID- 4368915
TI  - Micro hemagglutination-inhibition test for detection of CELO virus antibodies.

PMID- 4368916
TI  - Microcirculation and hypoxia.

PMID- 4368917
TI  - Mineral metabolism and skeletal development of lambs affected by Trichostrongylus
      colubriformis.

PMID- 4368918
TI  - Minimal change and focal sclerotic lesions in lipoid nephrosis.

PMID- 4368919
TI  - Mitochondrial heterosis.

PMID- 4368920
TI  - Mobility of protein molecules in Micrococcus lysodeikticus membranes.

PMID- 4368921
TI  - Modification of cysteine residues with sodium 2-bromoethanesulfonate. The
      application of S-sulfoethylated peptides in automatic Edman degradation.

PMID- 4368922
TI  - Modifications in the chromosomal proteins of SV-40 transformed WI-38 human
      diploid fibroblasts.

PMID- 4368923
TI  - Modifications in the purified rabbit skeletal muscle apophosphorylase-b assay of
      serum pyridoxal phosphate levels.

PMID- 4368924
TI  - Modified radioimmunoassay for murine sarcoma-leukemia virus group-specific
      antigen.
AB  - Iodination of disrupted Moloney strain murine sarcoma-leukemia virus resulted in
      labeled group-specific (gs) protein which was subsequently purified on an
      isoelectrofocusing column. This iodinated purified gs antigen, prepared from a
      relatively small quantity of purified virus, was used in a radioimmunoassay. A
      radioimmunoassay inhibition method was developed so that antibody specific for
      mammalian C-type gs antigen could be measured in undiluted or low dilutions of
      test serum without altering the known reagents of the test. The gs antigen
      isolated from purified Moloney strain murine sarcoma-leukemia virus has an
      isoelectric point (pH 5.95) which is significantly lower than that reported for
      other murine leukemia viruses.

PMID- 4368925
TI  - Modulation of the baroreceptor reflex by central administration of angiotensin.

PMID- 4368926
TI  - Molecular basis of the biological function of molybdenum. Molybdenum-free sulfite
      oxidase from livers of tungsten-treated rats.

PMID- 4368927
TI  - Molecular basis of the biological function of molybdenum. Molybdenum-free
      xanthine oxidase from livers of tungsten-treated rats.

PMID- 4368928
TI  - Molecular orbital studies of the conformation around the 5 position in
      angiotensin II.

PMID- 4368929
TI  - Molecular orbital study on the interaction between coenzymes and enzymes; NAD+ or
      NADH and dehydrogenases.

PMID- 4368930
TI  - Molecular weight of microsomal glucose-6-phosphatase of rat and human liver.

PMID- 4368931
TI  - Morphological basis of diffusion through the iris vessels in the dynamics of the
      aqueous humour.

PMID- 4368932
TI  - Morphological observations on visceral leishmaniasis in the Sudan.

PMID- 4368933
TI  - Motor end-plate fine structure in acrylamide dying-back neuropathy: a sequential
      morphometric study.

PMID- 4368935
TI  - Mulibrey nanism; an inherited dysmorphic syndrome with characteristic ocular
      findings.

PMID- 4368936
TI  - Multicentric chemodectomata at high altitude. A case report and review of the
      literature.

PMID- 4368934
TI  - Motor unit recruitment as reflected by muscle fibre glycogen loss in a prosimian
      (bushbaby) after running and jumping.
AB  - A qualitative histochemical assessment of glycogen loss in biopsies was made in
      bush-babies after running and jumping. Glycogen loss was related to the specific
      type of exercise. After running, glycogen loss was greatest in the slow-twitch
      oxidative fibre and depletion in the fast-twitch oxidative glycolytic fibres was
      similarly greater than in the fast-twitch glycolytic fibres. After jumping, the
      opposite pattern of glycogen utilization occurred (FG>FOG>SO).

PMID- 4368937
TI  - Multiple aggregation states of phosphoribosyladenosine triphosphate synthetase.

PMID- 4368939
TI  - Multiple primary carcinomas of respiratory tract: primary carcinoma of larynx
      followed by primary carcinomas involving two lungs consecutively.

PMID- 4368938
TI  - Multiple forms of solubilized gonadotropin receptors from the rat testis.

PMID- 4368942
TI  - Mutagenicity of thioxanthenes (hycanthone, lucanthone and four indazole
      derivatives) at the TK locus in cultured mammalian cells.

PMID- 4368940
TI  - Murine cytomegalovirus-infected liver: depletion of acid phosphatase with
      concomitant increase of alkaline phosphate.

PMID- 4368941
TI  - Muscle length and neuromuscular transmission in the frog.

PMID- 4368943
TI  - Mutagens in the biosphere.

PMID- 4368944
TI  - Mutant of Salmonella typhimurium that channels infecting bacteriophage P22 toward
      lysogenization.
AB  - A slowly growing, polymyxin-sensitive mutant of Salmonella typhimurium was
      isolated. Wild-type phage P22 form plaques on the mutant at 5 x 10(-4), the
      frequency observed on wild-type hosts. All P22 clear mutants form plaques with
      near normal frequency. The inability of the mutant to form plaques is correlated
      with an increase in lysogenization frequency. The cause of the increased
      lysogenization frequency is not known, but it is not the result of overproduction
      of cyclic adenosine 5'-monophosphate.

PMID- 4368945
TI  - Myelin enzymes and protein metabolism.

PMID- 4368947
TI  - Mossbauer studies of some complexes of the undecapeptide of cytochrome c.

PMID- 4368946
TI  - Myocardial function and lipid metabolism in the chronic alcoholic animal.
AB  - In view of the variables that obscure the pathogenesis of cardiomyopathy, a study
      was undertaken in mongrel dogs fed ethanol as 36% of calories for up to 22 mo.
      Both the experimental and control groups maintained body weight, hematocrit,
      plasma vitamin, and protein levels. Left ventricular function was evaluated in
      the intact anesthetized dog using indicator dilution for end-diastolic and stroke
      volume determinations. During increased afterload with angiotensin, the ethanol
      group exhibited a larger rise of end-diastolic pressure (P<0.01), whereas end
      diastolic and stroke volume responses were significantly less than in controls.
      Preload increments with saline elicited a significantly higher end-diastolic
      pressure rise in the ethanol group (P<0.01). No hypertrophy, inflammation, or
      fibrosis was present and it was postulated that the enhanced diastolic stiffness
      was related to accumulation of Alcian Blue-positive material in the ventricular
      interstitium. To evaluate myocardial lipid metabolism, [1-(14)C]oleic acid was
      infused systemically. Plasma specific activity and myocardial lipid uptake were
      similar in both groups. There was a significantly increased incorporation of
      label into triglyceride, associated with a reduced (14)CO(2) production,
      considered the basis for a twofold increment of triglyceride content. In
      addition, diminished incorporation of [(14)C]oleic acid into phospholipid was
      observed accompanied by morphologic abnormalities of cardiac cell membranes.
      Potassium loss and sodium gain, like the lipid alteration, was more prominent in
      the subendocardium. Thus, chronic ethanol ingestion in this animal model is
      associated with abnormalities of ventricular function without evident
      malnutrition, analogous to the preclinical malfunction described in the human
      alcoholic.

PMID- 4368948
TI  - N-oxide formation and related reactions in drug metabolism.

PMID- 4368949
TI  - Needle biopsies in pulmonary diagnostics.

PMID- 4368950
TI  - Neo-natal mortality of puppies in Queensland caused by canine herpesvirus
      infection.

PMID- 4368951
TI  - Neonatal hematuria.

PMID- 4368952
TI  - Neural-tube defects and herpesvirus type 2--test of a hypothesis.

PMID- 4368953
TI  - Neurilemmoma of the choroid in Recklinghausen's disease.

PMID- 4368954
TI  - Neurophysiologic mechanisms of hemiplegic and paraplegic spasticity: implications
      for therapy.

PMID- 4368955
TI  - Neutralizing antibodies to herpesvirus types 1 and 2 in carcinoma of the cervix,
      carcinoma in situ and cervical dysplasia.

PMID- 4368956
TI  - Neutralizing antibodies to herpesvirus types 1 and 2 in Montreal women.

PMID- 4368957
TI  - New experimental approaches.

PMID- 4368958
TI  - No evidence for a carbohydrate moiety affecting the clearance of circulating
      human leukocyte interferon in rabbits.

PMID- 4368959
TI  - Non-metastatic neurological minifestations of malignant disease.

PMID- 4368960
TI  - Non-polio virus interference with oral polio vaccine immunization: possible
      influence of physical climate and socio-economic status.

PMID- 4368961
TI  - Non-transmitting neuromuscular junctions during an early stage of end-plate
      reinnervation.
AB  - 1. Electrophysiological studies were made on regenerating motor end-plates in
      frog cutaneous pectoris muscle after crushing the motor nerve.2. The pattern of
      degenerative and regenerative changes is similar to that already described for
      the frog sartorius, although it occurs more quickly in the cutaneous pectoris.
      Resumption of synaptic transmission first occurs after 9 days, in muscle fibres
      closest to the nerve crush. During the subsequent 12 days synaptic contact is
      progressively re-established across the muscle.3. During the period of
      regeneration muscle fibres can be found which have been reinnervated, but which
      do not produce an end-plate potential in response to stimulation of the nerve
      trunk. This is referred to as the ;non-transmitting' stage of regeneration.4.
      Increases in extracellular potassium, addition of lanthanum to the bath and focal
      extracellular stimulation all indicate that the axon terminals at non
      transmitting junctions do have a releasable supply of neurotransmitter. Focal
      stimulation occasionally sets up active responses in these nerve terminals.5. It
      is concluded that this ;non-transmitting' stage results from failure of action
      potential propagation in the regenerating neurone proximal to the end-plate
      region.

PMID- 4368962
TI  - Nonfunctioning nonchromaffin paraganglioma of the pancreas.

PMID- 4368963
TI  - Novikoff hepatoma nuclear 8-18S RNA.

PMID- 4368964
TI  - Nuclear concentration of estriol in superfused human endometrium; competition
      with estradiol.

PMID- 4368965
TI  - Nuclear receptor-estrogen complexes of rat uteri: concentration-time-response
      parameters.

PMID- 4368967
TI  - Nucleotide pyrophosphatase, a sialoglycoprotein located on the hepatocyte
      surface.

PMID- 4368968
TI  - Nucleotide sequence analysis of bacteriophage DNA.

PMID- 4368966
TI  - Nuclear ribonucleoprotein complexes containing polyadenylate from mouse ascites
      cells.
AB  - Nuclear poly(A)-containing RNA of mouse ascites cells can be extracted in the
      form of 15-17S ribonucleoprotein complexes under conditions in which the bulk of
      the heterogeneous nuclear RNA is released as 30S complexes. The poly(A)
      containing fraction of nuclear extracts has been resolved into two distinct
      components, 15 and 17 S; neither contains the two polypeptides of 30S
      ribonucleoprotein. The 17S particle contains approximately six polypeptide
      species of molecular masses 17,000-30,000 daltons. The 15S complex has four
      distinct polypeptides of higher molecular mass, including a prominent 80,000
      dalton species.

PMID- 4368969
TI  - NADH brain surface scanning and 3-D computer display.

PMID- 4368970
TI  - NADH, a physiological electron donor in clostridial nitrogen fixation.

PMID- 4368971
TI  - NH2-terminal sequence of yeast inorganic pyrophosphatase.

PMID- 4368972
TI  - N6-(delta2-isopentenyl)adenosine 5'-monophosphate: formation and effect on purine
      metabolism in cellular and enzymatic systems.

PMID- 4368973
TI  - Observations on the structural arrangement of the somatic sensory innervation in
      the iris of mammals.

PMID- 4368975
TI  - Observations on vibrio eltor.

PMID- 4368976
TI  - Occupational therapist in home health.

PMID- 4368974
TI  - Observations on uptake of herpes simplex virus in organized cultures of mammalian
      nervous tissue.

PMID- 4368977
TI  - On the development of a well-defined source of superoxide ion for studies with
      biological systems.

PMID- 4368978
TI  - On the electron donor property of veratrine.

PMID- 4368979
TI  - On the interaction of periodate oxidized GDP and its borohydride reduction
      product with the elongation factors Tu and G from Escherichia coli.

PMID- 4368980
TI  - On the mechanism of erythropoietin-induced differentiation. 13. The role of
      sialic acid in erythropoietin action.

PMID- 4368981
TI  - On the nature of the spin coupling between the iron-sulfur clusters in the eight
      iron ferredoxins.

PMID- 4368982
TI  - Oncolytic action of prostaglandins.

PMID- 4368984
TI  - Oral infection of Culicoides variipennis with bluetongue virus: development of
      susceptible and resistant lines from a colony population.

PMID- 4368983
TI  - One-step separation of human plasma angiotensinogen from renin.

PMID- 4368985
TI  - Origin of asymmetry in biomolecules.

PMID- 4368986
TI  - Oxaziridines as possible intermediates in flavin monooxygenases.
AB  - The enzymatic hydroxylation reactions of flavin monooxygenases are suggested to
      involve an oxaziridine as the active oxygenating agent. The chemistry of these
      monooxygenases and their nonenzymatic model systems are consistent with an
      oxaziridine intermediate. Several advantages of the oxaziridine model over the
      previously proposed "carbonyl oxide" and flavin peroxide models are discussed.

PMID- 4368987
TI  - Oxygen poisoning in the unanesthetized brain: correlation of the oxidation
      reduction state of pyridine nucleotide with electrical activity.

PMID- 4368988
TI  - Paediatric ophthalmology in Northern Finland--a population investigation.

PMID- 4368989
TI  - Pancreatic surgery in the 1960s.

PMID- 4368990
TI  - Parental compliance with postdischarge recommendations for retarded children.

PMID- 4368991
TI  - Partial inhibition of hydroxyurea on liver tumors induced by N, N-dimethyl-4
      aminoazobenzene.

PMID- 4368992
TI  - Partial nephrectomy--a pathological evaluation.

PMID- 4368993
TI  - Participation of mononuclear phagocytes in chronic inflammatory diseases.

PMID- 4368994
TI  - Particles similar to mouse leukaemia virus in Ehrlich's ascites carcinoma and in
      reticulum cell noeplasms type B. An electron microscopic study in mice.

PMID- 4368995
TI  - Patterns of changes in brain carbohydrate metabolites, amino acids and organic
      phosphates at increased carbon dioxide tensions.

PMID- 4368996
TI  - Patterns of spontaneous cortisol and growth hormone secretion in rhesus monkeys
      during the sleep-waking cycle.

PMID- 4368997
TI  - Pellicular immobilized enzymes.

PMID- 4368998
TI  - Pelvic arteriography in the diagnosis of malignant trophoblastic disease.

PMID- 4368999
TI  - Peptide hormones.

PMID- 4369001
TI  - Persistence of complement-fixing antibodies in guinea pig sera serially collected
      in large volumes.

PMID- 4369002
TI  - Persistence of late SV40 genome transcription after inhibition of DNA relication
      by cytosine arabinoside.

PMID- 4369000
TI  - Peptide synthesis.

PMID- 4369003
TI  - Persistent albuminuria and meningitis caused by congenital cytomegalovirus
      infection. A case report of cytomegalic inclusion disease.

PMID- 4369004
TI  - Pharmacological evaluation of a new Ca2+ antagonist, 8-(N,N-diethylamino)-octyl
      3,4,5-trimethoxybenzoate hydrochloride (TMB-8): studies in smooth muscles.

PMID- 4369005
TI  - Phase specific surface autoantigens on membranes of fetus and tumors.

PMID- 4369006
TI  - Phosphatase activity of methicillin-resistant and methicillin-sensitive cells of
      Staphylococcus aureus.

PMID- 4369007
TI  - Phospholipids and acyl groups of subcellular membrane fractions from human
      intracranial tumors.
AB  - The phospholipids from subcellular fractions of human intracranial tumors were
      examined. For comparison, microsomes were isolated from a fetal human brain and
      from the gray matter of adult human brains. The subcellular membranes of tumors
      had a higher protein-to-phospholipid ratio than the normal brain membranes. The
      microsomes from tumors had a lower proportion of
      diacylglycerophosphorylethanolamine and higher proportions of
      alkenylacylglycerophosphorylcholine and sphingomyelin (plus
      diacylglycerophosphorylinositol) than microsomes from the gray matter. Also, the
      ratios of alkenylacylglycerophosphorylethanolamine to
      diacylglycerophosphorylethanolamine were higher in the tumors than in the normal
      controls. The acyl groups of ethanolamine phosphoglycerides in tumor microsomes
      had relatively more 18:1, 18:2, and 20:4(n - 6) and less 18:0, 22:4(n - 6), and
      22:6(n - 3) than the adult brain gray matter. Except for the increase in 18:2,
      acyl group changes in choline phosphoglycerides between tumors and controls were
      not as extensive as in the ethanolamine phosphoglycerides. The characteristic
      features of phospholipids and their constituent acyl groups of tumors were often
      present in all the subcellular fractions. Although the acyl group profiles of the
      tumor phosphoglycerides were in closer resemblance to the fetal brain than to the
      adult brain, other differences were observed. Results indicate that neoplastic
      brain cells are unique in their cellular composition, and consequently they
      deviate from the normal neurons and glials in metabolism and functions.

PMID- 4369008
TI  - Phosphonolipids. XXVI. Mixed-acid phosphonocephalins: synthesis of alpha'
      stearoyl-beta-oleoyl-l-alpha-glyceryl-(2-aminoethyl)phosphonate.

PMID- 4369009
TI  - Phosphorylation of a zymogen granule membrane polypeptide from rat pancreas.

PMID- 4369010
TI  - Phosphorylation of nuclear proteins during muscle differentiation in vitro.

PMID- 4369011
TI  - Phosphorylation of proteins in rat liver. Endogenous phosphorylation and
      dephosphorylation of proteins from smooth and rough endoplasmic reticulum and
      free ribosomes.

PMID- 4369012
TI  - Photoinactivation of ammonia oxidation in Nitrosomonas.
AB  - Photoinactivation of ammonia oxidation in cells of Nitrosomonas was shown to
      follow first-order kinetics with a rate constant proportional to incident light
      intensity. The action spectrum for photoinactivation consisted of a broad peak in
      the ultraviolet range, where both hydroxylamine and ammonia oxidation were
      affected, and a shoulder at approximately 410 nm where only ammonia oxidation was
      affected. In photoinactivated cells, hydroxylamine but not ammonia was oxidized
      to nitrite and hydroxylamine but not ammonia caused reduction of cytochromes in
      vivo. The amount per cell of the following constituents was not measurably
      altered by photoinactivation: cytochromes b, c, a, and P460; ubiquinone;
      phospholipid; free amino acids; hydroxylamine-dependent nitrite synthetase;
      nitrite reductase; p-phenylenediamine oxidase; and cytochrome c oxidase.
      Malonaldehyde or lipid peroxides were not detected in photoinactivated cells.
      Photoinactivation was prevented (i) under anaerobic conditions, (ii) in the
      presence of methanol, allylthiourea, thiosemicarbazide, hydroxylamine,
      ethylxanthate, or CO at concentrations wich caused 100% inhibition of ammonia
      oxidation, and (iii) at concentrations of ammonia or hydroxylamine which gave a
      rapid rate of nitrite production. Recovery of ammonia oxidation activity in 90%
      inactivated cells took place in 6 h, required an energy and/or nitrogen source,
      and was inhibited by 400 mug of chloramphenicol per ml.

PMID- 4369013
TI  - Phylogenetic aspects of adrenocortical activity during the process of adaptation.

PMID- 4369014
TI  - Physical and chemical properties of opossum hemoglobin. A hemoglobin containing
      glutamine at position 58 (E7) in the alpha subunit.

PMID- 4369015
TI  - Physico-chemical properties of chromatin of mouse sperm nuclei in heterokaryons
      with Chinese hamster cells.

PMID- 4369016
TI  - Plant sterol metabolism. Enzymatic cleavage of the 9beta, 19beta-cyclopropane
      ring of cyclopropyl sterols in bramble tissue cultures.

PMID- 4369017
TI  - Plants gathered as foodstuffs by the Transkeian peoples.

PMID- 4369019
TI  - Plasma cortisol in children with fulminating meningococcal infection.

PMID- 4369018
TI  - Plasma adenosine 3',5'-cyclic monophosphate in human hypertension.
AB  - In a previous study we observed an increase in urinary cyclic AMP in labile
      hypertension in the upright position and during isoproterenol infusion, in
      contrast to a decrease in control subjects. In the present study we measured the
      plasma level of cyclic AMP in control subjects and patients with various types of
      hypertension. We obtained the following results: (1) plasma cyclic AMP increases
      in response to upright posture in control subjects and hypertensive patients; (2)
      values of cyclic AMP in the recumbent and upright positions are comparable in
      control subjects and patients with essential hypertension, but are significantly
      higher in those with true renovascular hypertension due to bilateral renal artery
      stenosis; (3) propranolol inhibits the increase of plasma cyclic AMP in response
      to posture in control subjects, but has an opposite effect in labile hypertension
      where there is a further increase; (4) the rise in blood pressure in
      pheochromocytoma is associated with a considerable increase in plasma cyclic
      AMP.Present and previous data suggest that kidney handling of cyclic AMP is
      abnormal in hypertension, and that the specific defect may be related to the type
      of hypertension.

PMID- 4369020
TI  - Plasma post-heparin lipolytic activity in patients with malabsorption: effect of
      intravenous fat administration.

PMID- 4369021
TI  - Plasminogen, the serum proenzyme activated by factors from cells transformed by
      oncogenic viruses.

PMID- 4369022
TI  - Platelet electrophoresis: the present position.

PMID- 4369023
TI  - Platelet retention in glass bead columns: further evidence for the importance of
      ADP.

PMID- 4369024
TI  - Polymyositis without inflammation.

PMID- 4369025
TI  - Polypeptide composition of rat high density lipoprotein: characterization by SDS
      gel electrophoresis.

PMID- 4369026
TI  - Polypeptide distribution of the main lipoprotein density classes separated from
      human plasma by rate zonal ultracentrifugation.

PMID- 4369027
TI  - Population dynamics of mitochondria. I. A model for the role to ACTH in the
      degradation of adrenocortical mitochondria.

PMID- 4369028
TI  - Possible dapsone-induced peripheral neuropathy in dermatitis herpetiformis.

PMID- 4369029
TI  - Postsynaptic responses of motor cortex neurons of cats to sensory stimulation of
      different modalities.

PMID- 4369030
TI  - Prediction of breast cancer response to endocrine therapy.

PMID- 4369031
TI  - Preliminary crystallographic data for cytochrome c' of Rhodopseudomonas
      palustris.

PMID- 4369032
TI  - Prenatal viral infection with particular reference to cytomegaloviruses.

PMID- 4369033
TI  - Preparation and properties of a cell-free, hormonally responsive adenylate
      cyclase from guinea pig brain.

PMID- 4369035
TI  - Preparation of avian ribosomes with low levels of contaminating elongation
      factors.

PMID- 4369034
TI  - Preparation of adenosine nucleotide derivatives suitable for affinity
      chromatography.
AB  - Methods of synthesizing a series of chemically-defined AMP, ADP, ATP, adenylyl
      imidodiphosphate and pyrophosphate derivatives suitable for affinity
      chromatography are extensively described. Each derivative has a single primary
      amino group at the end of a hexamethylene ;spacer' chain for attachment to CNBr
      activated agarose. The synthesis of the derivative where the ;spacer' arm is
      attached directly to the 8 position of the adenine ring to produce 8-(6
      aminohexyl)amino-AMP involves the direct bromination of AMP in the 8 position
      followed by displacement of the halogen by 1,6-diaminohexane. This monophosphate
      derivative can then be converted into the corresponding di- or triphosphate forms
      by direct phosphate condensation with carbonyl di-imidazole. A second series of
      adenosine phosphate derivatives with the phosphate moieties unsubstituted has
      been similarly prepared from N(6)-(6-aminohexyl)-AMP (Guilford et al., 1972). A
      third type of ligand has been synthesized by condensing the phosphoryl
      imidazolide of AMP with 6-aminohex-1-yl phosphate. This compound, P(1)-(6
      aminohex-1-yl) P(2)-(5'-adenosyl) pyrophosphate, has an unsubstituted adenine
      ring. The synthesis of a fourth type of ligand, 6-aminohex-1-yl pyrophosphate,
      was done by heating 6-aminohexan-1-ol with crystalline pyrophosphoric acid under
      reduced pressure. The structures of the synthesized compounds were confirmed by
      chemical, electrophoretic and chromatographic methods and by u.v. spectrometry.
      The general applicability of the synthetic methods used is discussed in relation
      to the preparation of other affinity adsorbents. Examples are given where these
      derivatives have been successful in reversibly binding dehydrogenases, kinases
      and myosin and its proteolytic subfragments. The partial purification of rat
      liver glucokinase on an ADP derivative is shown.

PMID- 4369037
TI  - Pressure response of pulmonary vasculature to vasoconstricting agents.

PMID- 4369036
TI  - Preparation of 3-chloroacetylpyridine adenine dinucleotide: an alkylating
      analogue of NAD+.

PMID- 4369038
TI  - Prevention by metallothionein of cadmium-induced inhibition of vitamin D
      activation reaction in kidney.

PMID- 4369039
TI  - Prevention of hemolysis by bivalent metal ions during virus-induced fusion of
      erythrocytes with Ehrlich ascites tumor cells.

PMID- 4369040
TI  - Prevention of the generalized Shwartzman reaction and endotoxin lethality by
      polymyxin B localized in tissues.
AB  - Pretreatment with multiple doses of polymyxin B and colistimethate was evaluated
      as to its ability to sequester sufficient antibiotic in tissues to neutralize the
      effects of endotoxin in three animal models. Animals were challenged with
      endotoxin 24, 48, or 72 h after the last dose of antibiotic when there was
      minimal or not detectable drug in serum. Pretreatment with polymyxin B was
      successful in preventing the generalized Shwartzman reaction in rabbits and
      reducing endotoxin lethality in mice; however, large doses (20 mg per kg per day
      for 2 or 4 days) were required. Prolongation by more than 24 h of the interval
      between the last dose of polymyxin B and endotoxin challenge resulted in
      reduction or loss of protection. Dogs were unable to tolerate the high polymyxin
      B dosage which was protective in the mouse and rabbit. Lower, nontoxic doses of
      polymyxin B in dogs did not prevent endotoxin shock and lethality, even when
      challenged as soon as 1 h after the last dose. Pretreatment with colistimethate
      was ineffective in all three animal models.

PMID- 4369041
TI  - Primary cause of decreased functional reserve in the liver of icteric patients
      and rats.

PMID- 4369042
TI  - Primary hepatoma and invasive lobular carcinoma of breast without cirrhosis.

PMID- 4369043
TI  - Primary mucinous (adenocystic) carcinoma of the skin.

PMID- 4369044
TI  - Primary structure of lobster-muscle arginine kinase. Isolation and
      characterization of the fragments produced by cyanogen-bromide cleavage.

PMID- 4369045
TI  - Probenecide sensitive 3'-5'-cyclic AMP secretion by isoproterenol stimulated
      glial cells in culture.

PMID- 4369047
TI  - Proceedings: Effect of temperature on the regulatory properties of poikilothermic
      enzymes.

PMID- 4369046
TI  - Proceedings: Do the anterior pituitary and adrenal cortex participate in the
      reflex response of the adrenal medulla to arterial hypoxia?

PMID- 4369048
TI  - Proceedings: Effects of electrical and chemical stimulation of the central
      nervous system on sodium chloride and water intake.

PMID- 4369050
TI  - Proceedings: Glycine receptors in the cerebral cortex are probably transport
      receptors.

PMID- 4369049
TI  - Proceedings: Feed-back control of corticotrophin in the rat.

PMID- 4369051
TI  - Proceedings: Humoral control of periodical changes of nervous excitability.

PMID- 4369052
TI  - Proceedings: Hydroxylation of steroids and electron microscopy in adrenals from
      rats bearing an ACTH secreting tumor.

PMID- 4369053
TI  - Proceedings: Intraneuronal distributions and metabolic pathways of the adrenergic
      neurotransmitter.

PMID- 4369054
TI  - Proceedings: Liver and adipose tissue metabolism in rats with acute insulin
      deficiency induced by total pancreatectomy.

PMID- 4369055
TI  - Proceedings: Malacoplakia in childhood.

PMID- 4369056
TI  - Proceedings: Modification of the receptive field properties of neurones in the
      visual cortex by bicuculline, a GABA antagonist.

PMID- 4369057
TI  - Proceedings: Neurotrophic effects upon muscles and receptors of the cat's tongue.

PMID- 4369058
TI  - Proceedings: Pancreas and hypophysis in liver ketone body production.

PMID- 4369060
TI  - Proceedings: Primary hepatic cancer in childhood.

PMID- 4369059
TI  - Proceedings: Physiological implication of the metabolism of androgen in brain.

PMID- 4369061
TI  - Proceedings: Regulatory mechanisms of sodium appetite.

PMID- 4369062
TI  - Proceedings: Some similarities and differences between renin and sustained
      pressor principle.

PMID- 4369063
TI  - Proceedings: Stimulation and inhibition of renin production in monolayer cultures
      of kidney cells.

PMID- 4369064
TI  - Proceedings: Synthetic angiotensin inhibiting peptides.

PMID- 4369065
TI  - Proceedings: The brain renin-angiotensin system. Its physiological role.

PMID- 4369066
TI  - Proceedings: The effect of reserpine on pituitary-adrenocortical function in the
      rat.

PMID- 4369068
TI  - Proceedings: The renin--angiotensin system in experimental renal hypertension.

PMID- 4369067
TI  - Proceedings: The mechanism of action of estrogens.

PMID- 4369069
TI  - Proceedings: The role of the presynaptic receptors in regulating noradrenaline
      overflow by nerve stimulation.

PMID- 4369070
TI  - Prognostic value of ERG (oscillatory potential) in juvenile diabetics.

PMID- 4369071
TI  - Prolactin stimulation of estrogen receptor in vitro in 7,12
      dimethylbenz(A)anthracene-induced mammary tumor.

PMID- 4369072
TI  - Prolonged culture of Visna virus in human astrocytes.

PMID- 4369073
TI  - Prolylcarboxypeptidase in biological fluids.

PMID- 4369074
TI  - Properties of feline leukemia virus. II. In vitro labeling of the polypeptides.
AB  - Radioactive labeling of proteins from guanidine-hydrochloride disrupted feline
      leukemia virus was done in vitro by attaching [(3)H]methyl groups to protein
      amino groups with reductive alkylation. When in vitro labeled disrupted virus was
      analyzed by gel filtration in the presence of 6 M guanidine-hydrochloride the
      expected six major and one minor protein peaks were detected. When the same
      preparation was analyzed by immunodiffusion, the three antigens tested were found
      to have retained their antigenic activity.

PMID- 4369075
TI  - Properties of partially purified liver microsomal cytochrome P-450: acceptance of
      two electrons during anaerobic titration.

PMID- 4369076
TI  - Properties of the abnormal human plasma lipoprotein (LP-X) characteristic of
      cholestasis after chemical modification with succinic anhydride.

PMID- 4369078
TI  - Properties of the Sezary lymphoid cell. An ultrastructural analysis.

PMID- 4369077
TI  - Properties of the nicotinamide adenine dinucleotide-specific isocitrate
      dehydrogenase from Blastocladiella emersonii.

PMID- 4369079
TI  - Properties of Clostridium perfringens (welchii) type-A alpha-toxin (phospholipase
      C) purified by electrofocusing.

PMID- 4369080
TI  - Prostaglandin inhibition of cartilage chondromucoprotein synthesis: concept of
      "intrinsic activity".

PMID- 4369081
TI  - Prostaglandin receptors in human and ovine adrenal glands: binding and
      stimulation of adenyl cyclase in subcellular preparations.

PMID- 4369082
TI  - Protein kinases in testes of adult and prepuberal rats.

PMID- 4369083
TI  - Protein metabolism in tumor cells at various stages of growth in vivo.
AB  - Protein metabolism of Yoshida ascites hepatoma cells was studied in the early
      phase of logarithmic proliferation and in the following stage in which cell mass
      remains constant (resting phase). The rate of protein synthesis was measured by a
      short-time incorporation of [(8)H]lysine, while degradation was concurrently
      assessed by following the decrease of specific activity of [(14)C]lysine-labeled
      proteins. Most of the labeled amino acid injected intraperitoneally into the
      animal was immediately available for the tumor cells, with only a minor loss
      towards the extra-ascitic compartment. It was thus possible to calculate the
      dilution of the isotope in the ascitic pool of the lysine, which increased
      concurrently with the ascitic plasma volume. Amino acid transport capacity did
      not change in the log vs. the resting cells. This fact permitted the correction
      of the specific activity of the proteins synthesized by tumors in the two phases,
      taking into account the dilution effect. Protein synthesis was found to proceed
      at a constant rate throughout each of the two phases, although it was 30% lower
      during the resting as compared to the log phase. When cell mass attained the
      steady-state, protein degradation occurred at such a level as to balance the
      synthesis. Throughout the resting phase the amount of lysine taken up by the
      cells and renewed from the blood remained unchanged. Protein turnover, as studied
      in subcellular fractions, exhibited a similar rate in nuclei and microsomes,
      where it proceeded at a higher level than in mitochondria. On the whole, the
      results encourage the use of the Yoshida ascites hepatoma as a suitable model for
      studying protein turnover in relation to cell growth in vivo.

PMID- 4369084
TI  - Protein-losing enteropathy in primary lymphoedema: mesenteric lymphography and
      gut resection.

PMID- 4369085
TI  - Proteins specified by herpes simplex virus. XII. The virion polypeptides of type
      1 strains.
AB  - The polypeptides from purified virions of a herpes simplex 1 (human herpes-virus
      1) strain, F1, which had been passaged a limited number of times in cell culture
      after isolation, formed 33 bands on electrophoretic separation in polyacrylamide
      gels cross-linked with N, N'-diallyltartardiamide in contrast to a maximum
      resolution of only 24 to 25 bands in gels cross-linked with N, N'
      methylenebisacrylamide. This increase in the number of bands was due chiefly to
      an improved separation of glycosylated polypeptides from nonglycosylated
      polypeptides with which they co-electrophoresed on methylenebisacrylamide cross
      linked gels. Purified virions of HSV-1 [F1] had a protein/DNA mass ratio of 10.7
      +/- 0.96, and based on a DNA molecular mass of 85 x 10(6) to 100 x 10(6) the
      estimated weight of virion polypeptides ranges from 16.4 to 19.4 x 10(-16) g. The
      number of molecules of each polypeptide per virion ranged from less than 50 to
      1,500. Comparison of the virion polypeptides of two HSV-1 strains with similar
      isolation and limited passage history with those of four HSV-1 strains with
      histories of numerous passages outside the human host showed a number of
      nonrandom variations in virion polypeptides. Thus, although the virion
      polypeptides of two strains with similar isolation and limited passage history
      could not be differentiated, strains with extended passage histories differed
      markedly from each other and from the limited passage strains in the number and
      electrophoretic mobility of noncapsid polypeptides and notably in those of the
      envelope.

PMID- 4369086
TI  - Proteolipids.

PMID- 4369088
TI  - Psychiatric nursing: facilitating the development of a helping person.

PMID- 4369087
TI  - Psychiatric drugs and trends. Review of the phenothiazines. II.

PMID- 4369089
TI  - Psychiatric patients' impressions of teaching conferences.

PMID- 4369090
TI  - Purification and characterization of Streptomyces sialidases.
AB  - Some strains of Streptomyces produce sialidases. Two sialidases were purified
      over 1,000-fold from a culture filtrate of two Streptomyces species. They had the
      same properties in molecular weight, behavior to ions and other reagents, and
      substrate specificity. They showed very small differences in kinetic properties,
      pH optima, and heat stability. These Streptomyces sialidases differed markedly
      from Clostridium perfringens sialidase in molecular weight, p
      chloromercuribenzoate sensitivity, and substrate specificity. Approximate
      molecular weights of the sialidases from Streptomyces and C. perfringens were
      32,000 and 57,000, respectively. p-Chloromercuribenzoate (10(-3) M) caused
      complete inhibition of C. perfringens sialidase but not of Streptomyces
      sialidases.

PMID- 4369091
TI  - Purification and propeties of (plus)-cis-naphthalene dihydrodiol dehydrogenase of
      Pseudomonas putida.
AB  - Cells of Pseudomonas putida, after growth with naphthalene as sole source of
      carbon and energy, contain an enzyme that oxidizes (+)-cis-1(r),2(s)-dihydroxy
      1,2-dihydronaphthalene to 1,2-dihydroxynaphthalene. The purified enzyme has a
      molecular weight of 102,000 and apparently consists of four 25,500 molecular
      weight subunits. The enzyme is specific for nicotinamide adenine dinucleotide as
      an electron acceptor and also oxidizes several other cis-dihydrodiols. However,
      no enzymatic activity was observed with trans-1,2-dihydronaphthalene, or the K
      region cis-dihydrodiols of carcinogenic polycyclic hydrocarbons.

PMID- 4369092
TI  - Purification and regulatory properties of phosphoribulokinase from Hydrogenomonas
      eutropha H 16.
AB  - 1. Phosphoribulokinase was purified 286-fold from extracts of autotrophically
      grown cells. 2. The enzyme had a molecular weight of 237000 and showed a pH
      optimum of 9.0 in both crude extracts and purified preparation. MgCl(2) was
      required for activity; full activation was obtained at 5mm-MgCl(2) and the K(m)
      was approx. 0.5mm. 3. The ATP-saturation curve was sigmoidal and the degree of
      positive co-operativity increased at higher MgCl(2) concentrations. The ATP
      binding sites appeared to be non-interacting at low ribulose 5-phosphate
      concentrations. 4. Lineweaver-Burk plots for ribulose 5-phosphate showed abrupt
      transitions between apparently linear sections. The apparent K(m) and V(max.)
      values increased with increasing concentrations of ribulose phosphate. The
      transitions may be explained by a sequence of negative and positive co
      operativity in the catalytic rate constants. 5. Phosphoribulokinase activity was
      inhibited by AMP and phosphoenolpyruvate and was activated by NADH. The presence
      of AMP or phosphoenolpyruvate increased s(0.5) (substrate concentration required
      for half-maximal velocity) for both ribulose 5-phosphate and ATP but V(max.) was
      not changed. The sigmoidicity of the ATP-saturation curve increased in the
      presence of AMP but was not affected by phosphoenolpyruvate. The transitions in
      the ribulose 5-phosphate-saturation curves were more abrupt in the presence of
      either inhibitor. NADH lowered the s(0.5) for both ribulose 5-phosphate and ATP.
      The activator did not affect the degree of positive co-operativity between ATP
      binding sites, but the ribulose 5-phosphate-binding sites appeared to be non
      interacting in its presence. 6. A sequence of positive and negative co
      operativity in the interactions of AMP-binding sites was suggested by the Hill
      plots. In the presence of NADH (and phosphoenolpyruvate) the sensitivity to
      inhibition by AMP was less below a certain AMP concentration and increased above
      that concentration. 7. Examination of the interactions between ligands indicated
      that phosphoribulokinase can be regulated effectively by changes in effector
      concentrations similar to those reported to occur in vivo.

PMID- 4369093
TI  - Purification of messenger RNA and heterogeneous nuclear RNA containing poly(a)
      sequences.

PMID- 4369094
TI  - Purification of the cAMP receptor protein by affinity chromatography.

PMID- 4369095
TI  - Purification of Escherichia coli ADPglucose pyrophosphorylase by affinity
      chromatography.

PMID- 4369097
TI  - Pyrophosphate arthropathy: a clinical study of fifty cases.

PMID- 4369096
TI  - Purification of N-acetyl D-glucosamine-binding proteins by affinity
      chromatography.

PMID- 4369098
TI  - P430, a possible primary electron acceptor in Rhodospirillum rubrum.

PMID- 4369099
TI  - Quantitative aspects of iodothyronine binding by cytosol proteins of rat liver
      and kidney.

PMID- 4369101
TI  - Quantum chemical study of the thermodynamics, kinetics of formation and bonding
      of H2CN: relevance to prebiotic chemistry.

PMID- 4369100
TI  - Quantitative determination of bile acids and their conjugates using thin-layer
      chromatography and a purified 3alpha-hydroxysteroid dehydrogenase.

PMID- 4369102
TI  - Rabbit intubation and halothane anesthesia.

PMID- 4369103
TI  - Radiation treatment of intraocular cancer metastases.

PMID- 4369104
TI  - Radiation-killed BCG in the treatment of transplanted rat tumours.

PMID- 4369105
TI  - Radiographic anatomy of normal cerebral deep medullary veins: criteria for
      distinguishing them from their abnormal counterparts.

PMID- 4369107
TI  - Radiologic diagnosis of carcinoma of the biliary tree.

PMID- 4369106
TI  - Radioimmunologic determination of plasma unconjugated estriol in normal and
      abnormal pregnancies with a specific antiserum to estriol.

PMID- 4369108
TI  - Rapid degradation of puromycyl peptides in hepatoma cells and reticulocytes.

PMID- 4369109
TI  - Rapid determination of estriol of pregnancy by spectrodensitometry of thin layer
      chromatograms.

PMID- 4369110
TI  - Rapid diagnosis and typind of herpesvirus hominis by the fluorescent antibody
      method.

PMID- 4369111
TI  - Rapid isolation of a plant microsomal fraction by Mg2+--precipitation.

PMID- 4369112
TI  - Rapidly fatal cytomegalovirus pneumonia in Hodgkin's disease.

PMID- 4369113
TI  - Rate constants for the reactions of OH radicals with the enzyme proteins as
      determined by the p-nitrosodimethylaniline method.

PMID- 4369114
TI  - Re-examination of the sequence of the C-terminal tryptic fragment from porcine
      adrenocorticotropic hormone.

PMID- 4369116
TI  - Reaction of nucleosides with N-trimethylsilylimidazole: separation of TMS
      derivatives of anomeric pyrimidine nucleosides by gas-liquid chromatography.

PMID- 4369115
TI  - Reaction of alantolactone, an allergenic sesquiterpene lactone, with some amino
      acids. Resultant loss of immunologic reactivity.

PMID- 4369117
TI  - Reassociation and reactivation of lactic dehydrogenase from the unfolded
      subunits.

PMID- 4369118
TI  - Recent advances in glycogen metabolism.

PMID- 4369119
TI  - Recent advances in wound healing.

PMID- 4369120
TI  - Recent views on tremors and their treatment.

PMID- 4369121
TI  - Receptors and acceptors: a necessary distinction in hormone binding studies.

PMID- 4369122
TI  - Recombination of human erythrocyte apoprotein and lipid. I. Interaction of
      apoprotein and lipid at the air-water interface.

PMID- 4369123
TI  - Recommended methods for the determination of four enzymes in blood.

PMID- 4369124
TI  - Recurrent herpes simplex virus infections.

PMID- 4369125
TI  - Reduced nicotinamide adenine dinucleotide cytochrome o reductase associated with
      cytochrome o purified from Vitreoscilla. Evidence for an intermediate oxygenated
      form of cytochrome o.

PMID- 4369126
TI  - Reduction of the pressor response to angiotensin and norepinephrine in the rat,
      induced by a renal peptide.

PMID- 4369128
TI  - Regulation of amino acid transport in chick embryo heart cells. IV. Site and
      mechanisms of insulin action.

PMID- 4369127
TI  - Regulation of adenosine 3':5'-monophosphate content in human astrocytoma cells by
      adenosine and the adenine nucleotides.

PMID- 4369129
TI  - Regulation of cellular sterol flux and synthesis by human serum lipoproteins.

PMID- 4369130
TI  - Regulation of hormone stimulation of adipose tissue lipolysis by guanosine
      triphosphate.

PMID- 4369131
TI  - Regulation of steroid biosynthesis.

PMID- 4369132
TI  - Regulation of synthesis of two immunologically distinct nucleic acid-dependent
      nucleoside triphosphate phosphohydrolases in vaccinia virus-infected HeLa cells.
AB  - The two nucleic acid-dependent nucleoside triphosphate phosphohydrolases,
      previously purified from vaccinia virus cores, were shown to be immunologically
      distinct enzymes. Antiserum prepared against purified phosphohydrolase I and
      antiserum prepared against purified phosphohydrolase II only neutralized the
      activity of that enzyme used as antigen. Both enzymes were induced in HeLa cells
      after vaccinia infection. DNA-cellulose chromatography was used to purify the two
      phosphohydrolases from the cytoplasms of infected cells. The enzymes were
      identified by their different substrate specificities, nucleic acid dependence,
      and neutralization with specific antiserum. A third chromatographically separable
      nucleic acid-dependent phosphohydrolase similar to phosphohydrolase I in
      substrate specificity but not neutralizable by antiserum to either
      phosphohydrolase I or II, was also isolated from infected cells. No nucleic acid
      dependent nucleoside triphosphate phosphohydrolase activity was detected by
      similar methods from uninfected HeLa cells. Formation of these virus-induced
      enzymes was prevented by actinomycin D and cycloheximide, indicating a
      requirement for de novo RNA and protein synthesis, respectively. The kinetics of
      induction and inhibition by cytosine arabinoside, an inhibitor of DNA synthesis,
      suggested that synthesis of the phosphohydrolases is a late viral function.
      Rifampin, an inhibitor of vaccinia virus growth which prevents virion assembly,
      had no inhibitory effect on the induction of the phosphohydrolases. This result
      was consistent with the finding that these enzymes exist in a soluble as well as
      in a particulate form in the cytoplasm of infected cells. Addition of another
      specific anti-poxviral drug, isatin-beta-thiosemicarbazone, to vaccinia-infected
      cells partially inhibited induction of the phosphohydrolases.

PMID- 4369133
TI  - Regulation of the mammalian pyruvate dehydrogenase multienzyme complex by Mg2+
      and the adenine nucleotide pool.

PMID- 4369134
TI  - Relative stabilities of the intermediate reducible crosslinks present in collagen
      fibres.

PMID- 4369135
TI  - Relaxation of catabolite repression and loss of valine sensitivity in Escherichia
      coli K-12.

PMID- 4369136
TI  - Relaxation spectra of rabbit muscle lactate dehydrogenase and
      tetraiodofluorescein.

PMID- 4369137
TI  - Release of lipopolysaccharide, phospholipids and enzymes from Salmonella
      enteritidis by ethylenediaminetetra-acetic acid.

PMID- 4369138
TI  - Remarks about angiographic findings in cases of pontine tumor.

PMID- 4369139
TI  - Renal transplantation in hypophosphatemia with vitamin D-resistant rickets.

PMID- 4369140
TI  - Renin-angiotensin-aldosterone system of a woman with Bartter's syndrome:
      Juxtaglomerular cell hyperplasia without hypertension.

PMID- 4369141
TI  - Reovirus-associated mortality in broiler chickens.

PMID- 4369142
TI  - Replacement of ribothymidine by 5-methyl-2-thiouridine in sequence GT psi C in
      tRNA of an extreme thermophile.

PMID- 4369143
TI  - Replication of mouse-tropic and xenotropic strains of murine leukemia virus in
      human x mouse hybrid cells.
AB  - The replication of mouse-tropic and xenotropic strains of murine leukemia virus
      in human x mouse hybrid cells was investigated. NB-tropic strains of the leukemia
      virus replicated efficiently in several hybrid lines, including those that
      contained a complete complement of human chromosomes and many mouse chromosomes.
      In lines with only a few mouse chromosomes, NB-tropic viruses failed to
      replicate. N- and B-tropic viruses replicated in human x N-type and human x B
      type cells, respectively. The N- and B-tropic viruses replicating in these hybrid
      cells retained their original tropism. The viral restrictive functions of the
      mouse Fv-1 locus were expressed in the hybrid cells, restricting the replication
      of N- and B-tropic strains in human x B-type and human x N-type mouse cells,
      respectively. In contrast to mouse-tropic viruses, AT-124 virus, a xenotropic
      strain, replicated in human but not in mouse cells or in hybrid cells containing
      a complete complement of human chromosomes and near complete complement of mouse
      chromosomes However, hybrid lines with only a few mouse chromosomes supported AT
      124 replication. Thus, human genes in hybrid cells do not restrict the
      replication of mouse or xenotropic murine leukemia virus strains, while mouse
      genes in such cells restrict xenotropic leukemia virus replication and, as
      determined by the mouse Fv-1 phenotype, mouse-tropic murine leukemia virus. These
      results indicate that exogenously applied mouse-tropic and xenotropic
      oncornaviruses exhibit different patterns of restriction in human-mouse hybrid
      cells and that such hybrid cells may be used for genetic analysis of oncornavirus
      replication.

PMID- 4369145
TI  - Requirement of L-serine for enzymic activation of carcinogen, 4
      hydroxyaminoquinoline 1-oxide.

PMID- 4369144
TI  - Requirement for cell division for initiation of transcription of Rous sarcoma
      virus RNA.
AB  - Stationary chicken embryo fibroblasts exposed to Rous sarcoma virus (RSV) did not
      synthesize virus RNA until after division of the infected cells. Initiation of
      RNA transcription after cell division resulted in transcription of the entire
      viral genome and was followed shortly thereafter by appearance of progeny virus.
      Addition of colchicine to RSV-infected stationary chicken embryo fibroblasts
      resulted in inhibition of cell division and a 24-h delay in the appearance of
      virus RNA. RSV-infected chicken embryo fibroblasts made stationary 10 to 15 cell
      generations after infection continued to produce an amount of progeny virus
      similar to that produced in dividing RSV-infected cells. Teh virus produced from
      cells made stationary after virus production had begun contained RNA synthesized
      in stationary cells. Therefore, division of the RSV-infected chicken embryo
      fibroblast is required for the initiation of transcription of virus RNA, but it
      is not required for the maintenance of transcription of virus RNA.

PMID- 4369147
TI  - Reticuloendothelial function in experimental injury and tolerance to shock.

PMID- 4369146
TI  - Respiratory deficiency in Saccharomyces carlsbergensis 4228 caused by thiamine
      and its prevention by pyridoxine.

PMID- 4369148
TI  - Retinoblastoma in Norway.

PMID- 4369149
TI  - Retrospective study of 117 patients with optic neuritis.

PMID- 4369150
TI  - Ribonucleoprotein complexes containing nascent DNA-like RNA in the crude
      chromatin fraction of rat liver.

PMID- 4369151
TI  - Rod outer segment phosphodiesterase: factors affecting the hydrolysis of cyclic
      AMP and cyclic-GMP.

PMID- 4369152
TI  - Role of cyclic nucleotides in cancer.

PMID- 4369153
TI  - Role of cyclic AMP in reproductive processes.

PMID- 4369154
TI  - Role of vasopressin and angiotensin in response of splanchnic resistance vessels
      to hemorrhage.

PMID- 4369155
TI  - Rorschach responses subsequent to REM deprivation in schizophrenic and
      nonschizophrenic patients.

PMID- 4369156
TI  - Sabin's vaccine used for nonspecific prevention of infant diarrhea of viral
      etiology.

PMID- 4369157
TI  - Salmonellosis and shigellosis at Boston City Hospital. 2. Susceptibility of
      strains of Salmonellae and Shigellae to antibacterial agents.

PMID- 4369158
TI  - Seasonal infection of Culex mosquitos and swine with Japanese encephalitis virus.
AB  - A year-round study of the infection rates of JE virus in Culex mosquitos was made
      during 1970-71 in 2 hamlets in Taoyuan County, China (Province of Taiwan). JE
      virus was recovered from 5 of 314 pools of C. annulus, and from 1 of 22 pools of
      C. tritaeniorhynchus; these recoveries occurred during a 14-day period in July
      1971. None of the 288 pools of C. p. fatigans, which had been collected between
      October and April, was positive. In addition, sentinel swine were assessed for
      antibody and virus. All the pigs became highly immune by 23 July; in each hamlet
      all the pigs had become infected within 1 week, virus being detected in them for
      only 1-2 weeks. Virus-positive mosquitos appeared to have obtained their
      infections at about the time that viraemia was occurring in the sentinel swine.
      These observations illustrate once again the lower infection rate and shorter
      duration of virus-positive mosquitos in China (Province of Taiwan) as compared
      with Japan.

PMID- 4369159
TI  - Secretion of apolipoproteins in very low density and high density lipoproteins by
      perfused rat liver.
AB  - The incorporation of labeled amino acids into the peptides of very low density
      lipoproteins (VLDL) and high density lipoproteins (HDL) secreted by perfused rat
      liver was studied using a Ringer-albumin solution in the perfusate in place of
      serum to diminish exchange of peptides between VLDL and HDL. Among the
      lipoproteins, the greatest release of protein, greatest incorporation of amino
      acid, and highest specific activity were found in VLDL. After separation of the
      delipidated peptides by electrophoresis on polyacrylamide gel, the incorporation
      into VLDL peptides was found to be 5-10 times as great as into HDL peptides.
      There was virtually no incorporation into the peptides of low density
      lipoproteins (LDL). Approximately 25% of the radioactivity incorporated into
      perfusate VLDL failed to enter the 13% polyacrylamide gel. The remaining
      radioactivity was distributed primarily among three peptide bands; one, found in
      the upper portion of the gel, contained 45% of the total, most of the remainder
      being found in two rapidly migrating bands. These three peptides appear to
      approximate those of human apo-C in relative electrophoretic mobility. Most of
      the HDL peptide radioactivity entering the running gel was found in a band that
      migrates slightly faster than the main VLDL band. A portion of the radioactivity
      of this major HDL band did not enter the running gel unless beta-mercaptoethanol
      was present. Greater separation of these two bands by polyacrylamide gel
      electrophoresis for 24 hr confirmed that the major bands in VLDL and in HDL were
      different. The rapidly moving peptides of HDL were found to contain very little
      radioactivity. Determination of the intensity of staining of carrier-free
      perfusate VLDL and HDL peptides produced a pattern similar to the incorporation
      of labeled amino acids. It is concluded that the rapidly moving peptides, which
      may contain activators of lipoprotein lipase, are only secreted as part of the
      VLDL.

PMID- 4369160
TI  - Selection and application of factors for forecasting the epidemic time and
      severity of Japanese encephalitis prevalence.

PMID- 4369161
TI  - Selective formation of desmosomes in chick cell reaggregates.

PMID- 4369162
TI  - Semen matrix calculi in a rhesus monkey (Macaca mulatta).

PMID- 4369163
TI  - Separate estimation of serum beta-lipoprotein cholesterol and pre-beta
      lipoprotein cholesterol: clinical aspects.

PMID- 4369164
TI  - Separation of the main lipoprotein density classes from human plasma by rate
      zonal ultracentrifugation.
AB  - The major lipoprotein density classes (chylomicrons-VLDL, LDL, HDL(2) and HDL(3))
      were isolated from human plasma in a two-step ultracentrifugal procedure using
      the Ti-14 zonal rotor. The isolation of the two major high density lipoprotein
      subclasses (HDL(2) and HDL(3)) was achieved in a 24-hr run using a nonlinear NaBr
      gradient in the density range of 1.00-1.40. The lipoproteins with a density <
      1.063 found in the rotor's center were isolated in a second run of 140 min
      duration using a continuous linear NaBr gradient in the density range of 1.00
      1.30. The isolated lipoproteins were analyzed for chemical composition and for
      electrophoretic mobility; purity of isolated fractions was checked by
      immunochemistry. The lipoproteins exhibited flotation rates, chemical
      compositions, and molecular weights similar to those found with the common
      sequential procedures in angle-head rotors. The amount of lipoprotein lipids in
      the bottom fraction of the zonal rotor was comparable to that of the angle-head
      rotor. The described method yields the main lipoprotein density classes free from
      albumin in a very short running time; compared with the rate-zonal techniques
      already in use, this method allows the quantitative separation of an additional
      lipoprotein density class (HDL(2)) without increasing the running time.
      Furthermore, this procedure proved to be suitable for isolation of plasma
      lipoproteins from subjects with various types and varying degrees of
      hyperlipoproteinemia.

PMID- 4369165
TI  - Separation of urinary androstanediol and pregnanediol isomers by a combined gas
      liquid chromatography-thin-layer chromatography method.

PMID- 4369166
TI  - Sequence dependent deamidation rates for model peptides of cytochrome C.

PMID- 4369167
TI  - Serologic testing of various primate species maintained in a single outdoor
      breeding colony.

PMID- 4369169
TI  - Serum parathyroid hormone concentrations in hypophosphataemic vitamin D resistant
      rickets.

PMID- 4369168
TI  - Serum hormone concentrations in ruminants during mammary growth, lactogenesis,
      and lactation: a review.

PMID- 4369170
TI  - Significance of respiratory virus isolations. A study in primary schoolchildren.

PMID- 4369171
TI  - Simian herpesviruses and neoplasia.

PMID- 4369172
TI  - Simple methods of preparing nicotinamide mononucleotide.

PMID- 4369173
TI  - Simultaneous bilateral fluorescein angiography of the anterior eye.

PMID- 4369174
TI  - Single dose irradiation in treatment of cerebral metastases from bronchial
      carcinoma.

PMID- 4369176
TI  - Sleep disorders. Recent findings in the diagnosis and treatment of disturbed
      sleep.

PMID- 4369175
TI  - Sleep and some psychoactive drugs.

PMID- 4369177
TI  - Sleep pattern and intelligence in functional mental retardation.

PMID- 4369178
TI  - Sleep-wakefulness cycle in adult rats suffered from icterus gravis neonatorum.

PMID- 4369179
TI  - Sleeping pills and dream content.

PMID- 4369180
TI  - Smallpox.

PMID- 4369181
TI  - So-called"virus-like" intranuclear filaments in brain autopsy material: a
      reappraisal on hand of two fatal cases of tick-borne encephalitis.

PMID- 4369182
TI  - Sodium-potassium-activated adenosine triphosphatase (NaK-ATPase) activity in the
      rat lens. A histochemical and biochemical study.

PMID- 4369183
TI  - Soluble gonadotropin receptors of the rat ovary.

PMID- 4369185
TI  - Some aspects on nervous control of aqueous humour dynamics in the rabbit eye.

PMID- 4369184
TI  - Soluble lymphocytic mediators. I. Inhibition of macrophage migration inhibitory
      factor production by drugs.

PMID- 4369186
TI  - Some characteristics of corticosterone uptake by the dorsal hippocampus and the
      adenohypophysis in the rat.

PMID- 4369188
TI  - Some fundamental considerations in the study of sleep.

PMID- 4369187
TI  - Some chemical parameters of serum, cerebrospinal fluid, perilymph, and aqueous
      humor of the chinchilla.

PMID- 4369189
TI  - Some histochemical reactions in the neurocytes of the trigeminal ganglion in
      rabbits.

PMID- 4369190
TI  - Some parasitic and other natural diseases of the African elephant in the Kruger
      National Park.

PMID- 4369191
TI  - Some properties of endothelial cells isolated from human umbilical cord vein.

PMID- 4369193
TI  - Some reactions of 1,6-di-O-p-tolylsulphonyl-D-mannitol and its derivatives.

PMID- 4369192
TI  - Some properties of the nitrogenase proteins from Clostridium pasteurianum.
      Molecular weight, subunit structure, isoelectric point and EPR spectra.

PMID- 4369194
TI  - Some studies of adrenal suppression by alternate-day prednisone therapy.

PMID- 4369196
TI  - Speaking out on: social change, social policy and the helping professional.

PMID- 4369195
TI  - Spacer arms in affinity chromatography: use of hydrophilic arms to control or
      eliminate nonbiospecific adsorption effects.

PMID- 4369197
TI  - Specific inactivation of fructose 1,6-bisphosphatase from Saccharomyces
      cerevisiae by a yeast protease.

PMID- 4369198
TI  - Specific inhibition of the renin-angiotensin system: A key to understanding blood
      pressure regulation.

PMID- 4369199
TI  - Specific interaction of 3H-FSH with rat testis binding sites.

PMID- 4369200
TI  - Specific RNA fragments in defective particles of bacteriophage MS2.

PMID- 4369201
TI  - Specificity of the natural rat liver ribonuclease inhibitor towards nuclease
      activities of subcellular fractions.

PMID- 4369202
TI  - Specificity of the retrograde axonal transport of nerve growth factor.

PMID- 4369203
TI  - Spectral characteristics and interconversions of the reduced oxidized, and
      oxygenated forms of purified cytochrome o.

PMID- 4369204
TI  - Spin labelling of D-glyceraldehyde-3-phosphate dehydrogenase with specific
      reagents.

PMID- 4369205
TI  - Spin-labeled polyuridylic acid. Formation of an intermediate structure.

PMID- 4369206
TI  - Spin-labelled phosphorylase as a probe in a rabbit muscle glycogen particle
      fraction.

PMID- 4369207
TI  - Splenomegaly, sex, and other characteristics of laboratory animals used for
      primary isolations of Coxiella burnetii.

PMID- 4369208
TI  - Spontaneous and stimulated secretion of QUSO-extractable immunoassayable ACTH in
      man.

PMID- 4369209
TI  - Spontaneous hematoma of the optic chiasma. Report of a case.

PMID- 4369210
TI  - Spontaneous tumours of the central nervous system of laboratory rats.

PMID- 4369211
TI  - Steroid metabolism in arrhenoblastoma.

PMID- 4369212
TI  - Steroid-induced bilateral femoral head ischaemic necrosis.

PMID- 4369213
TI  - Stimulation by D-glucose of cyclic adenosine 3':5'-monophosphate accumulation and
      insulin release in isolated pancreatic islets of the rat.

PMID- 4369214
TI  - Stimulation of a dopamine-sensitive adenylate cyclase in homogenates of rat
      striatum by a metabolite of piribedil (ET 495).

PMID- 4369215
TI  - Stimulation of melanogenesis in cultured melanoma cells by calciferols.

PMID- 4369216
TI  - Stimulation of sodium transport in turkey erythrocytes by cyclic 3',5'-AMP.

PMID- 4369218
TI  - Structural and functional changes in human and experimental neuropathy.

PMID- 4369217
TI  - Streptozotocin diabetes. Correlation with extent of depression of pancreatic
      islet nicotinamide adenine dinucleotide.
AB  - The diabetogenic activity of streptozotocin has been correlated with a reduction
      in pyridine nucleotide synthesis in the mouse pancreatic islet. To determine the
      specificity of this reduction for diabetogenicity, a comparative study of
      streptozotocin, its cytotoxic moiety, 1-methyl-1-nitrosourea, and alloxan was
      performed. Streptozotocin administered intraperitoneally (i.p.) producd a dose
      related reduction in islet NAD which was proportional to the degree of
      diabetogenicity. A diabetogenic dose, 200 mg/kg, attained a peak plasma N-nitroso
      intact streptozotocin concentration of 0.224 mumol/ml and reduced the mean islet
      NAD from a control of 0.78 to 0.15 pmol. At borderline, 150 mg/kg, and
      nondiabetogenic, 100 mg/kg, doses, plasma concentrations reached 0.161 and 0.136
      mumol/ml, and NAD was 0.36 and 0.86 pmol/islet, respectively. 1-Methyl-1
      nitrosourea, 100 mg/kg, attained a maximum N-nitroso intact 1-methyl-1
      nitrosourea concentration of 0.162 mumol/ml and reduced the mean NAD to 0.58
      pmol/islet, and was nondiabetogenic; 200 mg/kg attained a peak plasma
      concentration of 0.344 mumol/ml and depressed NAD to 0.38 pmol/islet, and was
      inconsistently diabetogenic. Islet NAD of 0.4 pmol/islet or greater is required
      for integrity of the beta cell. A diabetogenic dose of alloxan, 500 mg/kg, did
      not depress NAD, 0.85 pmol/islet, therefore confirming that its mechanism of
      diabetogenicity differs from that of streptozotocin. In vivo uptake of [methyl
      (14)C]streptozotocin by islets was 3.8 times that of [methyl-(14)C]-1-methyl-1
      nitrosourea, whereas uptake by the exocrine pancreas favored 1-methyl-1
      nitrosourea over streptozotocin 2.4:1. The decreased islet uptake of 1-methyl-1
      nitrosourea correlates with the 3.5 times increased molar dosage required to
      produce islet NAD depression comparable to that of streptozotocin, 150 mg/kg.
      These studies indicate that the glucose carrier of streptozotocin facilitates
      uptake of its cytotoxic group, 1-methyl-1-nitrosourea, into islets.

PMID- 4369219
TI  - Structural membrane proteins and loosely associated proteins of the sarcoplasmic
      reticulum.
AB  - The protein composition of sarcoplasmic-reticulum vesicles, either unpurified or
      after fractionation on sucrose gradients, and with or without previous osmotic
      shock and sonication, was investigated by electrophoresis in acid polyacrylamide
      gels. The pattern of release of loosely bound proteins is discussed with respect
      to their localization in the interior of the vesicles.

PMID- 4369221
TI  - Structure of bis(methylguanidinium) monohydrogen orthophosphate. A model for the
      arginine-phosphate interactions at the active site of staphylococcal nuclease and
      other phosphohydrolytic enzymes.

PMID- 4369220
TI  - Structural studies of a mitochondria-free plasma membrane fraction from rat
      liver.

PMID- 4369222
TI  - Structure-function relationship in rabbit muscle glyceraldehyde-3-phosphate
      dehydrogenase. Trinitrophenylation of the lysine residues.

PMID- 4369223
TI  - Structure-function relationships in foot-and-mouth disease virus.

PMID- 4369224
TI  - Studies of insulin, growth hormone and prolactin binding: ontogenesis, effects of
      sex and pregnancy.

PMID- 4369225
TI  - Studies of insulin, growth hormone and prolactin binding: tissue distribution,
      species variation and characterization.

PMID- 4369227
TI  - Studies on androgen and estrogen uptake by rat hypothalamus.

PMID- 4369226
TI  - Studies of the polysaccharide fraction from the lipopolysaccharide of Pseudomonas
      alcaligenes.
AB  - Studies of the lipopolysaccharide of Pseudomonas alcaligenes strain BR 1/2 were
      extended to the polysaccharide moiety. The crude polysaccharide, obtained by mild
      acid hydrolysis of the lipopolysaccharide, was fractionated by gel filtration.
      The major fraction was the phosphorylated polysaccharide, for which the
      approximate proportions of residues were; glucose (2), rhamnose (0.7), heptose (2
      3), galactosamine (1), alanine (1), 3-deoxy-2-octulonic acid (1), phosphorus (5
      6). The heptose was l-glycero-d-manno-heptose. The minor fractions from gel
      filtration contained free 3-deoxy-2-octulonic acid, P(i) and PP(i). The purified
      polysaccharide was studied by periodate oxidation, methylation analysis, partial
      hydrolysis, and dephosphorylation. All the rhamnose and part of the glucose and
      heptose occur as non-reducing terminal residues. Other glucose residues are 3
      substituted, and most heptose residues are esterified with condensed phosphate
      residues, possibly in the C-4 position. Free heptose and a heptosylglucose were
      isolated from a partial hydrolysate of the polysaccharide. The location of
      galactosamine in the polysaccharide was not established, but either the C-3 or C
      4 position appears to be substituted and a linkage to alanine was indicated. In
      its composition, the polysaccharide from Ps. alcaligenes resembles core
      polysaccharides from other pseudomonads: no possible side-chain polysaccharide
      was detected.

PMID- 4369228
TI  - Studies on free and 5 S RNA-bound ribosomal GTPase and ATPase.

PMID- 4369229
TI  - Studies on polynucleotides. The linkage of deoxyribopolynucleotide templates to
      cellulose and its use in their replication.

PMID- 4369230
TI  - Studies on proteins of animal ribosomes. XVII. Quantitative aspects of enzymatic
      phosphorylation of ribosomal proteins and particles from rat liver.

PMID- 4369231
TI  - Studies on pyrimidine biosynthesis in the granulocytes of patients receiving gold
      therapy for rheumatoid arthritis.

PMID- 4369232
TI  - Studies on the biology of the lung mite, Pneumonyssus simicola banks (Acarina:
      Halarachnidae) and diagnosis of infestation in macaques.

PMID- 4369234
TI  - Studies on the distribution of urea cycle enzymes in different regions of rat
      brain.

PMID- 4369233
TI  - Studies on the control of development. Differences in the pattern of DNA binding
      proteins isolated from vegetative and sporulating cells of Bacillus subtilis.

PMID- 4369235
TI  - Studies on the estrogen receptor in breast cancer.

PMID- 4369236
TI  - Studies on the immune response and pathogenesis of Sendai virus infection of
      mice. II. The immunoglobulin class of plasma cells in the bronchial sub-mucosa.

PMID- 4369237
TI  - Studies on the interaction of concanavalin A with major density classes of human
      plasma lipoproteins. Evidence for the specific binding of lipoprotein B in its
      associated and free forms.

PMID- 4369238
TI  - Studies on the minor components of the organic matrix of human dentine.

PMID- 4369239
TI  - Studies on the phosphorylation of nucleolar proteins. Identification of a
      nucleolus-associated protein kinase activity.

PMID- 4369240
TI  - Studies on the ultrastructure of the blood-aqueous barrier in the rabbit.

PMID- 4369241
TI  - Studies on 14C-imipramine metabolism in the isolated perfused rat liver.

PMID- 4369242
TI  - Studies with foot-and-mouth disease virus in British deer (red, fallow and roe).

PMID- 4369243
TI  - Studies with foot-and-mouth disease virus in British deer (red, fallow and roe).
      II. Recovery of virus and serological response.

PMID- 4369244
TI  - Study of the reactions of blood with artificial surfaces. Use of the
      thrombogenerator.

PMID- 4369245
TI  - Subacute sclerosing panencephalitis (SSPE). Reappraisal of nuclear, cytoplasmic
      and axonal inclusions ultrastructural study of eight cases.

PMID- 4369246
TI  - Subcellular distribution of sphingomyelinase and other acid hydrolases in
      different parts of the calf lens.

PMID- 4369247
TI  - Substructure of amphibian motor end plate. Evidence for a granular component
      projecting from the outer surface of the receptive membrane.
AB  - End-plate membrane has been examined at amphibian myoneural junctions by means of
      transmission electron microscopy of thin tissue sections. The postjunctional
      membrane exhibits morphologically specialized dense, convex patches which are
      located superficially facing the axon terminal but do not extend into the depths
      of the junctional folds. In the specialized regions the plasma membrane is
      approximately 120 A thick and trilaminar. The outer dense lamina is thickened by
      the presence in it of granular elements approximately 60-120 A in diameter which
      are spaced semiregularly at approximately 100-150-A intervals and which border
      the junctional cleft directly. In these regions the concentration of the granules
      is of the order of approximately 10(4)/microm(2), which is in the same range as
      the estimated concentration of receptor sites at other vertebrate cholinergic
      junctions. Filamentous projections can sometimes be seen extending from the
      granules to the overlying basement membrane, and in oblique views a reticular
      pattern may appear both in these patches and in the basement membrane. The
      cytoplasmic surface of the specialized membrane is covered with an amorphous and
      filamentous dense material whose distribution coincides with that of the granules
      visible in the outer layer and which may be connected to them across the
      membrane. In unosmicated specimens stained with permanganate and uranyl acetate
      the specialized regions exhibit the same morphological features but stand out
      sharply in contrast to adjacent areas of unspecialized membrane which appear only
      faintly. Such preparations are particularly useful in assessing the extent of the
      specialized membrane. It is proposed that the granules visible at the outer
      surface of the end-plate membrane represent acetylcholine receptors and that in
      amphibians, as in annelids, the receptors at myoneural junctions are concentrated
      into patches which occupy less than the total postjunctional membrane surface
      area.

PMID- 4369248
TI  - Subunit structure of testicular hyaluronidase.

PMID- 4369249
TI  - Sugar catabolism in Aquaspirillum gracile.
AB  - Aquaspirillum (Spirillum) gracile is one of the few spirilla that cause
      acidification of the medium when cultured with sugars. Acidic reactions have been
      reported only for d-glucose, d-galactose, and l-arabinose, and the mode of attack
      of these sugars has not been previously investigated. The soluble portion of
      extracts of glucose-cultured cells of A. gracile ATCC 19624 was found by
      spectrophotometric methods to contain enzyme activities characteristic of the
      Entner-Doudoroff and Embden-Meyerhof-Parnas pathways. No activity for 6
      phosphogluconate dehydrogenase (EC 1.1.1.44) was detected. Pyridine nucleotide
      linked dehydrogenase activities for l-arabinose and d-galactose (EC 1.1.1.46 and
      EC 1.1.1.48) occurred in the soluble fraction of cells cultured with either
      sugar. Glucose-cultured cells contained not only glucokinase (EC 2.7.1.2) and
      glucose-6-phosphate dehydrogenase (EC 1.1.1.49) activities but also glucose
      dehydrogenase (EC 1.1.1.47) activity. Enzymes capable of oxidizing gluconate were
      not detectable, but gluconokinase (EC 2.7.1.12) activity was present. Paper
      chromatographic analysis of the spent culture supernatant media from glucose
      cultured cells indicated an accumulation of gluconic acid, and this was confirmed
      by enzymatic methods. Evidence is presented for the production of d-galactonic
      and l-arabonic acids in cultures containing d-galactose or l-arabinose,
      respectively.

PMID- 4369251
TI  - Surface glycosyltransferases on cultured mouse fibroblasts.

PMID- 4369250
TI  - Superoxide dismutase activity in WI-38 cell cultures: effects of age,
      trypsinization and SV-40 transformation.

PMID- 4369252
TI  - Survival of Entamoeba and related Amoebae at low temperature. I. Viability of
      Entamoeba cysts at 4 degrees C.

PMID- 4369253
TI  - Synaptic regulation of specific protein synthesis in an identified neuron.

PMID- 4369254
TI  - Synergism between polymyxins, polysorbate and antimetabolites of folic acid
      synthesis, and a paper disc technique for routine testing for synergism.

PMID- 4369255
TI  - Synthesis and degradation of the major hepatic phosphofructokinase isozyme in rat
      liver and hepatoma 3924-A.

PMID- 4369256
TI  - Synthesis of (alpha-32P) ribo- and deoxyribonucleoside 5'-triphosphates.

PMID- 4369257
TI  - Synthesis of galactosylphytosphingosine and galactosylceramides containing
      phytosphingosine.

PMID- 4369258
TI  - Synthesis of substituted piperidino carbamides: correlation between CNS effects
      and selective inhibition of NAD-dependent oxidations.

PMID- 4369259
TI  - Synthesis of viral-specific RNA in cells infected with the parvovirus, Kilham rat
      virus.
AB  - We have studied the viral-specific RNA synthesized after infection of a
      permissive cell line with Kilham rat virus (KRV). The RNA was shown to be virus
      specific by analysis of its nucleotide base ratios and by hybridization with KRV
      and cellular DNA. Viral RNA is synthesized as early as 2 h after infection. This
      viral RNA synthesis occurs before viral progeny DNA synthesis which is initiated
      at 7 to 8 h after infection. The predominant viral RNA synthesized before and
      after viral progeny DNA synthesis has a sedimentation coefficient of
      approximately 18S in dimethylsulfoxide-sucrose gradients and a calculated
      molecular weight of 6.5 x 10(5) to 7.5 x 10(5). KRV contains a molecule of single
      stranded DNA with a molecular weight of approximately 1.6 x 10(6). If the viral
      specific 18S RNA is a homogenous species, it would account for 40 to 50% of the
      viral genome. A small amount of 26S viral RNA with a molecular weight of 1.6 x
      10(6) to 1.7 x 10(6) can also be detected. If this 26S RNA is a single viral
      specific entity, it could represent a transcription of the entire KRV genome.

PMID- 4369260
TI  - Systemic chromomycosis in Rana pipiens.

PMID- 4369261
TI  - Target cell polarity and membrane phosphorylation in relation to the mechanism of
      action of antidiuretic hormone.
AB  - The plasma membrane of the bovine renal collecting duct epithelial cell has been
      resolved into its apical (luminal) and basal-lateral (contraluminal) components
      by free flow electrophoresis. The contraluminal, but not the luminal, membrane
      was found to contain antidiuretic hormone-sensitive adenylate cyclase. The
      luminal membrane was found to contain a cyclic 3':5'-adenosine monophosphate
      sensitive self-phosphorylating system consisting of a membrane-bound protein
      kinase and its membrane-bound substrate(s); this intrinsic protein kinase was not
      present in the contraluminal membrane. These findings provide direct evidence
      that the initiating steps in the action of antidiuretic hormone on the kidney
      take place at the contraluminal pole of the hormonesensitive target cell and that
      the late or terminal steps occur at the luminal pole, where they involve an
      alteration in the level of membrane phosphorylation.

PMID- 4369262
TI  - Testosterone metabolism and 5 alpha-dihydrotestosterone-binding macromolecule in
      rat kidney.

PMID- 4369263
TI  - The adenohypophysial response to stress and its hypothalamic control.

PMID- 4369264
TI  - The advantages of drosophila for mutation studies.

PMID- 4369265
TI  - The amino acid sequences of the phosphorylated sites in troponin-I from rabbit
      skeletal muscle.

PMID- 4369266
TI  - The association of congenital malformations and malignant tumors in infants and
      children.

PMID- 4369268
TI  - The binding of quinacrine mustard to nucleic acids.

PMID- 4369267
TI  - The binding of dexamethasone and triamcinolone acetonide to glucocorticoid
      receptors in rat skeletal muscle.

PMID- 4369269
TI  - The biological oxidation of aromatic heterocyclic amines.

PMID- 4369270
TI  - The calcium ionophore A 23 187 as a probe for studying the role of Ca2+ ions in
      the mediation of carbachol effects on rat salivary glands: protein secretion and
      metabolism of phospholipids and glycogen.

PMID- 4369271
TI  - The carcinogenic effects of dimethylnitrosamine and nitrosomethylurea in European
      hamsters (Cricetus cricetus L.).
AB  - The carcinogenic effects of dimethylnitrosamine (DMN) and nitrosomethylurea (NMU)
      injected subcutaneously at 3 different dose levels in European hamsters were
      studied. DMN induced malignant haemangioendotheliomata of the liver and kidney,
      hepatocellular carcinomata and, in one animal, a cholangiocellular carcinoma. The
      effect of NMU was localized at the site of administration and resulted in
      subcutaneous fibrosarcomata, carcinosarcomata or epidermal carcinomata.

PMID- 4369272
TI  - The cardiodynamic effects and mechanism of action of bretylium tosylate.

PMID- 4369273
TI  - The cellular basis of immunosuppression caused by the radiation leukaemia virus.

PMID- 4369274
TI  - The chemical basis for the action of the vancomycin group of antibiotics.

PMID- 4369275
TI  - The continuing evolution of an estrogen-receptor model.

PMID- 4369276
TI  - The control of glycogen synthesis in the liver.

PMID- 4369277
TI  - The control of myelin synthesis and inborn errors of metabolism.

PMID- 4369278
TI  - The covalently bound flavin prosthetic group of beta-cyclopiazonate oxidocyclase.

PMID- 4369279
TI  - The demonstration of protein synthesis-dependent repair replication in
      Escherichia coli after treatment with the mono-alkylating agent ethyl methane
      sulphonate.

PMID- 4369280
TI  - The development of a new selective medium for the isolation of Brucella abortus
      from contaminated sources.

PMID- 4369282
TI  - The diagnostic value of radioimmunoassay in clinical medicine. Discussion.

PMID- 4369281
TI  - The diagnosis and management of myasthenia gravis.

PMID- 4369283
TI  - The distribution of genetic polymorphisms in patients with Down's syndrome.

PMID- 4369284
TI  - The dyslipoproteinemias.

PMID- 4369286
TI  - The effect of caffeine on the survival of u.v.-irradiated herpes simplex type 1
      virus.

PMID- 4369285
TI  - The effect of angiotensin-II intravenous infusion on plasma renin activity and
      prostaglandins A, E, and F levels in the uterine vein of the pregnant monkey.

PMID- 4369287
TI  - The effect of corticotropin on mouse spleen colony-forming cells.

PMID- 4369288
TI  - The effect of cAMP on phospholipid metabolism.

PMID- 4369289
TI  - The effect of disinfectants on bacteriophage phi chi X 174.

PMID- 4369290
TI  - The effect of early undernutrition on the calibre spectrum of the rat optic
      nerve. Amorphometric ultrastructural study.

PMID- 4369291
TI  - The effect of edema, hydrocortisone acetate, concurrent viral infection and
      immunization on the clearance of Pasteurella hemolytica from the bovine lung.
AB  - The influence of pulmonary edema, hydrocortisone, immunization against
      Pasteurella hemolytica and concurrent infection with parainfluenza-3 virus upon
      pulmonary clearance of aerosolized P. hemolytica was studied in 31 calves.
      Following the various treatments calves were challenged with an aerosol of P.
      hemolytica. One control calf was killed immediately after the aerosol and the
      numbers of bacteria in the lung taken as 100%. Two calves were killed four hours
      after challenge and the numbers of bacteria in the lungs were compared to the
      100% of the control calf. The result was the percentage clearance of bacteria at
      four hours. PULMONARY EDEMA WAS INDUCED BY THREE DIFFERENT METHODS: by an aerosol
      of histamine, by intravenous injection of endotoxin and by intravenous injection
      of croton oil emulsion. The edema impaired the clearance of P. hemolytica, which
      was reflected in high numbers of P. hemolytica present in the lungs at four hours
      after challenge: 260% after histamine, 300% and 400% after endotoxin and 92%
      after croton oil. SIX DAYS OF TREATMENT OF FOUR CALVES WITH HIGH DOSES OF
      HYDROCORTISONE ACETATE PRODUCED INCONSISTENT RESULTS: two calves treated with a
      higher daily dose (36 mg/kg) had normal clearance whereas two calves treated with
      a lower dose had pulmonary edema and displayed lowered clearance with 111% and
      31% respectively of P. hemolytica retained in the lungs four hours after
      challenge. Immunization of calves by three different methods, a subcutaneously
      injected bacterin of P. hemolytica (2 calves), single aerosol (2 calves) and four
      aerosols (4 calves) of live P. hemolytica was reflected in an accelerated
      pulmonary clearance of P. hemolytica (with a mean of 1.55% of bacteria retained
      at four hours). Concurrent infection with parainfluenza-3 virus did not lower the
      clearance of P. hemolytica in the lungs of 12 calves over 15 days except on the
      first day following the exposure to parainfluenza-3 virus. These calves had
      hemagglutinating antibodies against P. hemolytica before exposure.

PMID- 4369292
TI  - The effect of glucagon on the liver cell membrane potential.
AB  - 1. Intracellular recordings of membrane potential were made from superficial
      cells of isolated mouse liver segments superfused with physiological salt
      solutions.2. The mean resting cell membrane potential was -39.4 mV.3. Glucagon
      caused a dose-dependent membrane hyperpolarization which was detectable at 10(
      9)M and maximal (7 mV) at 10(-7)M. The hyperpolarization started within half a
      minute after exposure to glucagon. Secretion (2 x 10(-7)M) had no effect on the
      membrane potential.4. Adrenaline (10(-6)M) and isoprenaline (10(-6)M) also caused
      membrane hyperpolarization (4-6 mV). The effect of isoprenaline, but not that of
      adrenaline, was blocked by propranolol (5 x 10(-6)M).5. Dibutyryl adenosine 3',5'
      monophosphate (10(-3)M) caused a membrane hyperpolarization of 4-8 mV.6. In the
      absence of extracellular K or the presence of Strophanthin-G (10(-3)M) the
      resting potential was decreased and the response to glucagon reduced. During
      exposure to a solution containing 20 mM-K the resting potential was slightly
      enhanced and the amplitude of the glucagon-induced hyperpolarization reduced
      compared with control conditions.7. It is concluded that the effect of glucagon
      on the membrane potential is due to an interaction with specific membrane
      receptors probably leading to activation of the membrane-bound adenyl cyclase. It
      is probable that the hyperpolarization is mediated by cyclic AMP. The
      hyperpolarization induced by glucagon is dependent on a normal function of the
      membrane Na-K pump.

PMID- 4369293
TI  - The effect of growth conditions on NAD+ and NADH concentrations and the NAD+:NADH
      ratio in normal and transformed fibroblasts.

PMID- 4369294
TI  - The effect of hepatic injury upon the development of amoebic liver abscess in
      hamsters.

PMID- 4369295
TI  - The effect of hydrocortisone and bromodeoxyuridine (BUdR) on the Epstein-Barr
      herpes virus in human lymphoblastoid cell lines.

PMID- 4369296
TI  - The effect of intravenously administered prostaglandin E2 on rat uterine 3',5'
      adenosine monophosphate.

PMID- 4369297
TI  - The effect of noradrenaline and tyramine on cardiac contractility, cyclic AMP,
      and phosphorylase a in normal and hyperthyroid rats.

PMID- 4369298
TI  - The effect of polychlorinated biphenyls on liver gluconeogenic enzyme activities
      in rats during exposure to cold.

PMID- 4369299
TI  - The effect of tyrosinase on glyceraldehyde-3-phosphate dehydrogenase and
      glycerophosphate dehydrogenase.

PMID- 4369300
TI  - The effect of REM deprivation on depression.

PMID- 4369301
TI  - The effects of epinephrine, prostaglandins, and their antagonists on adenosine
      cyclic 3',5'-monophosphate concentrations and motility of the rat uterus.

PMID- 4369302
TI  - The effects of eye movement and dark-adaptation on transmission through the
      visual pathways of unrestrained cats.

PMID- 4369303
TI  - The effects of hyperosmolarity on the blood-brain barrier. A morphological and
      physiological correlation.

PMID- 4369305
TI  - The effects of parental composition on recidivism rates in delinquent girls.

PMID- 4369304
TI  - The effects of infusions of synthetic adrenocorticotrophin in the conscious calf.
AB  - 1. A technique is described by which the whole of the effluent blood from the
      right adrenal gland can be collected as required from conscious, unrestrained
      calves. The technique may be used to measure adrenal blood flow gravimetrically
      and to compute the output of adrenal hormones under various conditions in the
      normal calf.2. In a group of seven calves mean cortisol output from the right
      adrenal gland was found to vary between 20 and 40 ng.kg(-1) min(-1) and
      corticosterone between 6 and 18 ng.kg(-1) min(-1) during a 2 hr period, 24 hr
      after surgery.3. Intravenous infusions of synthetic adrenocorticotrophin (5
      ng.kg(-1) min(-1)) produced a significant increase in the output of both cortisol
      and corticosterone within 5 min. The output of both hormones rose to maximal
      values within 10-20 min and mean values of approximately 300 ng.kg(-1) min(-1)
      (cortisol) and 120 ng.kg(-1) min(-1) (corticosterone) were maintained thereafter
      for the duration of the infusion (120 min). The output of both steroids fell to
      values comparable with those observed initially within 45-60 min after the
      infusion was discontinued.4. These changes in glucocorticoid output in response
      to adrenocorticotrophin produced a significant rise in the concentration of both
      cortisol and corticosterone in peripheral plasma. It is noteworthy that the rise
      in the mean corticosterone concentration in the peripheral plasma was
      substantially less than that which might be expected from relating the rise in
      mean plasma cortisol concentration to cortisol output.5. The results of control
      experiments have eliminated the possibility that the sampling procedure might
      itself increase steroid output or peripheral plasma concentration. Comparison of
      results from calves of widely disparate ages (8-38 days) provided no evidence
      that either the resting output of cortisol or corticosterone or the response to
      adrenocorticotrophin changes with age within the range examined.6. Infusion of
      adrenocorticotrophin (5 ng.kg(-1) min(-1)) also stimulated an abrupt rise in
      adrenal blood flow; mean resting flow (210 +/- 23 mul.kg(-1)) increased by
      approximately 30% within 5 min and attained peak values (355-365 mul.kg(-1) min(
      1)) between 10 and 30 min. Thereafter, adrenal blood flow steadily decreased and
      then fell rapidly to within the resting range when the infusion was terminated.
      No significant changes in heart rate or aortic blood pressure occurred during
      these infusions.7. The results are discussed in relation to those obtained in
      other species and under differing conditions by other workers.

PMID- 4369307
TI  - The effects of theophylline on cyclic adenosine monophosphate metabolism in
      lymphocytes from open-angle glaucoma patients.

PMID- 4369306
TI  - The effects of thallium salts, with particular reference to the nervous system
      changes. A report of three cases.

PMID- 4369308
TI  - The epithelium of the urinary bladder of rock hyrax.

PMID- 4369309
TI  - The human plasma kallikrein-kinin system.

PMID- 4369310
TI  - The identification of intermediates in the reaction of pig heart lactate
      dehydrogenase with its substrates.
AB  - Pig heart lactate dehydrogenase was studied in the direction of pyruvate and NADH
      formation by recording rapid changes in extinction, proton concentration,
      nucleotide fluorescence and protein fluorescence. Experiments measuring
      extinction changes show that there is a very rapid formation of NADH within the
      first millisecond and that the amplitude of this phase (phase 1) increases
      threefold over the pH range 6-8. A second transient rate (phase 2) can also be
      distinguished (whose rate is pH-dependent), followed by a steady-state rate
      (phase 3) of NADH production. The sum of the amplitudes of the first two phases
      corresponds to 1mol of NADH produced/mol of active sites of lactate
      dehydrogenase. Experiments that measured the liberation of protons by using
      Phenol Red as an indicator show that no proton release occurs during the initial
      very rapid formation of NADH (phase 1), but protons are released during
      subsequent phases of NADH production. Fluorescence experiments help to
      characterize these phases, and show that the very rapid phase 1 corresponds to
      the establishment of an equilibrium between E(NAD) (Lactate) right harpoon over
      left harpoon H(+)E(NADH) (Pyruvate). This equilibrium can be altered by changing
      lactate concentration or pH, and the H(+)E(NADH) (Pyruvate) species formed has
      very low nucleotide fluorescence and quenched protein fluorescence. Phase 2
      corresponds to the dissociation of pyruvate and a proton from the complex with a
      rate constant of 1150s(-1). The observed rate constant is slower than this and is
      proportional to the position of the preceding equilibrium. The E(NADH) formed has
      high nucleotide fluorescence and quenched protein fluorescence. The reaction,
      which is rate-limiting during steady-state turnover, must then follow this step
      and be involved with dissociation of NADH from the enzyme or some conformational
      change immediately preceding dissociation. Several inhibitory complexes have also
      been studied including E(NAD+) (Oxamate) and E(NADH) (Oxamate') and the abortive
      ternary complex E(NADH) (Lactate). The rate of NADH dissociation from the enzyme
      was measured and found to be the same whether measured by ligand displacement or
      by relaxation experiments. These results are discussed in relation to the overall
      mechanism of lactate dehydrogenase turnover and the independence of the four
      binding sites in the active tetramer.

PMID- 4369311
TI  - The identification of phosphatidylglycerol in the rat, rabbit, monkey and human
      lung.

PMID- 4369313
TI  - The immunological system and the development of central nervous system lesions in
      acute viral infections.

PMID- 4369312
TI  - The immunological basis of glomerulonephritis.

PMID- 4369314
TI  - The in vivo effects of leucine dehydrogenase from Bacillus sphaericus.

PMID- 4369315
TI  - The incidence of cytomegalovirus among mentally retarded and microcephalic
      children in a state institution.

PMID- 4369316
TI  - The information content of protein amino acid sequences.

PMID- 4369317
TI  - The inhibition of brain choline kinase by hemicholinium-3.

PMID- 4369318
TI  - The inhibition of ribonuclease activity and the isolation of polysomes from
      leaves of the french bean, Phaseolus vulgaris.

PMID- 4369319
TI  - The intake, digestion and utilization of food and growth rate of lambs affected
      by Trichostrongylus colubriformis.

PMID- 4369320
TI  - The interaction of apolipoprotein-serine with phosphatidylcholine.

PMID- 4369321
TI  - The interaction of uterine estrogen receptors with DNA.

PMID- 4369322
TI  - The interaction of vasoactive intestinal polypeptide and secretin with liver-cell
      membranes.

PMID- 4369324
TI  - The lysosomal enzymes in lymphocytes. II. Activated lymphocytes.

PMID- 4369323
TI  - The lipids of the alga Spirulina.

PMID- 4369325
TI  - The mechanism of reaction of Cys- 149 of D-glyceraldehyde-3-phosphate
      dehydrogenase with p-hydroxy-mercuribenzoate.

PMID- 4369326
TI  - The metabolic response to exercise and exhaustion in normal and growth-hormone
      deficient children.

PMID- 4369327
TI  - The motor neuron surface and spinal shock.

PMID- 4369328
TI  - The motor unit profile of the rat soleus in experimental myopathy and
      reinnervation.

PMID- 4369330
TI  - The normal short child. Community study of children in Newcastle upon Tyne.

PMID- 4369329
TI  - The nature and distribution of enzymes catalyzing the conjugation of glutathione
      with foreign compounds.

PMID- 4369331
TI  - The nucleotide sequence of the cytoplasmic initiator transfer RNA of a mouse
      myeloma cell.

PMID- 4369332
TI  - The occurrence of intermediates in mitochondrial fatty acid oxidation.

PMID- 4369333
TI  - The organization of extraocular muscles in Anura.

PMID- 4369334
TI  - The pancreatic beta-cell recognition of insulin secretogogues. Influence of
      neuraminidase treatment on the release of insulin and the islet content of
      insulin, sialic acid, and cyclic adenosine 3':5'-monophosphate.

PMID- 4369335
TI  - The pathology of 3-Nitro-4-hydroxyphanylarsonic acid toxicity in turkeys.

PMID- 4369336
TI  - The peripheral lung pulse in pulmonary carcinoma. A cinedensigraphic study based
      on 174 proven cases.

PMID- 4369337
TI  - The phosphorylation sites of troponin I from white skeletal muscle of the rabbit.

PMID- 4369338
TI  - The poly(adenylic acid) sequence of mouse globin messenger RNA.

PMID- 4369341
TI  - The production of limit-oligonucleotide digests from phenylalanine tRNA
      (Escherichia coli) with snake venom phosphodiesterase.

PMID- 4369339
TI  - The preparation and properties of pyruvate kinase from yeast.
AB  - A new method is described for the preparation of pyruvate kinase from yeast. This
      eliminates proteolysis during the preparation. The molecular weight of yeast
      pyruvate kinase is 215000, and it is composed of four subunits. Such properties
      of the enzyme as its extinction coefficient, cold-lability, thiol-group
      reactivity and binding of Mn(2+) ions are compared with those previously reported
      for yeast pyruvate kinase prepared by different methods. The specific activity is
      significantly higher than previously observed, but otherwise the enzyme is
      similar, apart from its molecular weight and Mn(2+)-binding characteristics, to
      preparations from Saccharomyces cerevisiae obtained in this laboratory (e.g. Fell
      et al., 1972, and references therein) and that of C. H. Suelter (e.g. Kuczenski &
      Suelter, 1971, and references therein), and is different from the enzyme isolated
      from Saccharomyces carlsbergensis by B. Hess and his co-workers (e.g. Wieker &
      Hess, 1972, and references therein).

PMID- 4369340
TI  - The primary structure of apolopoprotein-serine.

PMID- 4369342
TI  - The production of superoxide radical during the decomposition of potassium
      peroxochromate(V).

PMID- 4369343
TI  - The psychogeriatric patient in hospital.
AB  - The records of 148 geriatric patients discharged from the Royal Ottawa Hospital
      over an 18-month period were studied. The readmission rate, 38%, was similar to
      that of all inpatients in this hospital. The largest diagnostic category was
      depressive neurosis. More women than men had diagnoses of affective disorders,
      while more men had organic brain disease; these differences were statistically
      significant. The average length of hospital stay was 25 days. Those patients with
      diagnoses of organic brain disease and alcoholism had shorter stays than those
      with affective disorders. The implications of these findings in terms of setting
      up a psychogeriatric unit are discussed.

PMID- 4369344
TI  - The purification of cell nuclei from calf uterus by zonal centrifugation in
      reorienting density gradients.

PMID- 4369345
TI  - The pH-dependence of ESR spectra from nitroxide probes in lecithin dispersions.

PMID- 4369346
TI  - The rate of cholesterol 'flip-flop' in lipid bilayers and its relation to
      membrane sterol pools.

PMID- 4369347
TI  - The rate-limiting step of adrenal steroidogenesis and adenosine 3':5'
      monophosphate.

PMID- 4369348
TI  - The regulation of calciferol-25-hydroxylase in the chick.

PMID- 4369349
TI  - The regulatory center of D-glyceraldehyde-3-phosphate dehydrogenase.

PMID- 4369350
TI  - The renin-angiotensin system in acute renal failure in rats.

PMID- 4369351
TI  - The renin-angiotensin system of uninephrectomized rats under diuretic treatment.

PMID- 4369352
TI  - The respiratory system of the marine bacterium Beneckea natriegens. Oxidation-
      reduction potentials of the cytochromes.

PMID- 4369354
TI  - The role of cyclic AMP in the regulation of steroid biosynthesis in testis
      tissue.

PMID- 4369353
TI  - The role of cyclic AMP in the modulation of cardiac contractility.

PMID- 4369355
TI  - The role of prolactin in the depressed or 'buffered' adrenocorticosteroid
      response of the rat.

PMID- 4369356
TI  - The role of sialic acid in determining the survival of transcortin in the
      circulation.

PMID- 4369357
TI  - The sensitivity of function tests in detecting liver damage in the rat.

PMID- 4369358
TI  - The sodium-potassium adenosinetriphosphatase.

PMID- 4369360
TI  - The stability of PGM and AK isoenzymes in human tissues.

PMID- 4369361
TI  - The stoichiometry of the three different types of copper in ascorbate oxidase
      from green zucchini squash.

PMID- 4369359
TI  - The specificity of dimethylbenzylrifampicin as an inhibitor of viral induced
      transformation.
AB  - The effect of 2',6'-dimethyl-N(4')-benzyl-N(4')- [desmethyl]rifampicin on viral
      transformation induced by two unrelated oncogenic viruses was compared.
      Transformation of Balb/3T3 cells by the small, DNA-containing papova virus simian
      virus 40 was completely normal under conditions where transformation by the
      large, RNA-containing oncornavirus murine sarcoma virus was inhibited more than
      150-fold. For these experiments a resistant variant of Balb/3T3 was selected that
      grows well in high concentrations of the drug, is not dependent on the drug for
      growth, and is probably not blocked at the level of drug uptake. These data show
      that dimethyl-benzylrifampicin specifically inhibits oncornavirus-induced
      transformation rather than nonspecifically inhibiting cellular growth or
      transformation.

PMID- 4369362
TI  - The structure of cytochrome oxidase membranes.

PMID- 4369363
TI  - The structure of the posterior piriform cortex in the dog.

PMID- 4369365
TI  - The surface structure of polyoma virus.

PMID- 4369364
TI  - The subfractionation of platelet membranes by zonal centrifugation:
      identification of surface membranes.

PMID- 4369367
TI  - The temperature-dependent enzymatic breakdown of ribosomal RNA of reticulocytes.
      The nucleoside plus mononucleotide fraction.

PMID- 4369368
TI  - The theme is change.

PMID- 4369366
TI  - The synthesis of encephalomyocarditis virus polypeptides in infected L-cells and
      cell-free systems.

PMID- 4369369
TI  - The treatment of muscular subaortic stenosis.

PMID- 4369370
TI  - The ultrastructure of cartilage cells in the epiphyses of long bones in the
      domestic fowl.

PMID- 4369371
TI  - The ultrastructure of Dentalium egg at the trefoil stage.

PMID- 4369373
TI  - The use of red light for handling wild rats.

PMID- 4369372
TI  - The use of deoxyfluoro-D-galactopyranoses in a study of yeast galactokinase
      specificity.
AB  - 1. 2-Deoxy-2-fluoro-d-galactose, 3-deoxy-3-fluoro-d-galactose, 4-deoxy-4-fluoro-d
      galactose, 6-deoxy-6-fluoro-d-galactose and 2-deoxy-d-lyxo-hexose are substrates
      for yeast galactokinase. 2. The variation in K(m) values for the d-hexose
      derivatives was not associated with a variation in the value of K(m) for MgATP(2
      ) indicating that the binding of MgATP(2-) is not modified by the binding of the
      sugar substrate. 3. Donated H bonds from OH-3, OH-4 and OH-6 and an accepted H
      bond to OH-2 of the d-hexose are important for the binding of the sugar substrate
      to galactokinase. 4. Yeast galactokinase exhibits similar kinetics to the
      galactokinase from Escherichia coli and operates by a similar random sequential
      mechanism. 5. 4-Deoxy-4-fluoro-d-glucose was neither a substrate for nor an
      inhibitor of yeast galactokinase.

PMID- 4369375
TI  - The RNA of defective vesicular stomatitis virus particles in relation to viral
      cistrons.

PMID- 4369376
TI  - The SV40-induced T-antigen in mouse cells.

PMID- 4369374
TI  - The use of ribosubstitution techniques for determining DNA sequences.

PMID- 4369377
TI  - Theory of hormone-receptor interaction. 3. The endocrine target cell as a quantal
      response unit: a general control mechanism.

PMID- 4369378
TI  - Theory of radioimmunoassays and hormone-receptor interactions. II. Simulation of
      antibody divalency, cooperativity and allosteric effects.

PMID- 4369379
TI  - Thermography of the eye during cold stress.

PMID- 4369380
TI  - Thymic lymphocytes in obese (ob-ob) mice. A mirror of the insulin receptor defect
      in liver and fat.

PMID- 4369381
TI  - Thymus graft in four children: clinical and immunological results.

PMID- 4369382
TI  - Thyroid function following partial thyroidectomy.

PMID- 4369383
TI  - Thyroid lymphography.

PMID- 4369384
TI  - Tissue differences in the concentration of triiodothyronine nuclear binding sites
      in the rat: liver, kidney, pituitary, heart, brain, spleen, and testis.

PMID- 4369385
TI  - Toxic effects of anticonvulsants: general principles.

PMID- 4369386
TI  - Toxic polyneuropathy due to glue sniffing.
AB  - Four cases of toxic polyneuropathy due to glue-sniffing were reported.
      Neurological examination revealed motor predominant mixed type polyneuropathy.
      The cause of polyneuropathies in these cases was considered to be due to the
      inhalation of the vaporized elements of the adhesive agent, which contain mainly
      n-hexane and toluene. N-hexane is considered to be chiefly responsible for the
      polyneuropathy, though toluene also could have some influence on the illness.

PMID- 4369387
TI  - Toxic properties of chlorine trifluoride.

PMID- 4369388
TI  - Toxicity studies on tertrasul. II. Short-term comparative studies in 6 animal
      species.

PMID- 4369389
TI  - Toxicity studies on tetrasul. 3. Short-term comparative studies in rats with
      tetrasul and structurally related acaricides.

PMID- 4369390
TI  - Transcortin: a corticosteroid-binding protein of plasma. XII. Immunologic studies
      on transcortin in guinea-pig tissues.

PMID- 4369392
TI  - Transfection of chicken embryo cells with DNA extracted from avian virus
      producing neoplastic cells.
AB  - DNA isolated from avian virus-producing leukemic myeloblasts induced the
      production of viruses, but not morphological transformation, in cultivated
      chicken fibroblasts. The recovered virus had the same biological characteristics
      as the original avian myeloblastosis virus (AMV) and produced myeloblastosis and
      nephroblastomas when injected into chickens. Neutralization experiments with
      chicken anti-AMV-BAI strain A sera showed an antigenic community between the DNA
      transfected virus and the original virus. Virus induced in fibroblasts after
      treatment with DNA from a viral nephroblastic nephroblastoma line only gave
      nephroblastoma when injected into chicken. Treatment of chicken embryo cells with
      DNA extracted from normal chicken embryos did not induce viral production.

PMID- 4369391
TI  - Transcribing complexes in cells infected by vesicular stomatitis virus and rabies
      virus.
AB  - We analyzed cell extracts from BHK(21) cells infected with vesicular stomatitis
      virus (VSV) and rabies virus for in vitro RNA polymerase activity. Cells infected
      with VSV B virions exhibited several complexes with in vitro RNA polymerase
      activity in sucrose gradients. These complexes synthesize VSV transcriptase
      product (4 to 18S) polyadenylated in RNA complementary to virion RNA. Cells
      infected with a high multiplicity of B virions and T particles show only one RNA
      polymerase complex active in vitro. This complex sediments at 110S and makes only
      small (2S) RNA. Carrier BHK(21) cells persistently noncytopathically infected
      with VSV contain several complexes active in RNA polymerase, but both exhibit
      very low activity. Cytoplasms of cells noncytopathically infected with rabies
      virus also show very low levels of a complex containing RNA polymerase activity.
      No transcriptase nor any other in vitro polymerase activity could be found
      associated with purified rabies virions, although they do carry out primary
      transcription in cells treated with actinomycin D and cycloheximide before
      infection.

PMID- 4369393
TI  - Transfer of very low density lipoprotein from hen plasma into egg yolk.

PMID- 4369394
TI  - Transient monoclonal gammopathy associated with cytomegalovirus infection.

PMID- 4369395
TI  - Translation of reovirus mRNA, poliovirus RNA and bacteriophage Qbeta RNA in cell
      free extracts of mammalian cells.

PMID- 4369396
TI  - Treatment of a case of sympathetic ophthalmia.

PMID- 4369398
TI  - Treatment of retinoblastoma.

PMID- 4369399
TI  - Treatment of stabilized liver cirrhosis by dehydroepiandrosterone sulphate. I.
      Evaluation of principal biochemical tests as a whole.

PMID- 4369397
TI  - Treatment of hyperlipoproteinaemia type II A with a new anion exchange resin
      secholex.

PMID- 4369401
TI  - Trisomy-9 in the bone marrow of a patient with acute myelomonoblastic leukaemia.

PMID- 4369400
TI  - Trehalose metabolism by Bacillus popilliae.
AB  - Trehalose was found to be utilized more readily than glucose for the growth of
      Bacillus popilliae NRRL B-2309MC. The pathway of degradation of trehalose was
      elucidated and found to differ from that reported for other organisms. Trehalase
      and trehalose phosphorylase activities could not be detected. Rather, trehalose
      was found to undergo phosphoenolpyruvate (PEP)-dependent phosphorylation, and the
      resulting trehalose 6-phosphate was cleaved by a phosphotrehalase to equimolar
      amounts of glucose and glucose 6-phosphate. The phosphotrehalase was purified 34
      fold and shown to have a pH optimum of 6.5 to 7.0 and a K(m) for trehalose 6
      phosphate of 1.8 mM. A mutant missing the phosphotrehalase failed to grow on
      trehalose but grew normally on other sugars. The mutant accumulated
      [(14)C]trehalose as [(14)C]trehalose 6-phosphate. Phosphorylation of trehalose by
      dialyzed extracts was at least 25 times faster with PEP than with adenosine 5'
      triphosphate, and the phosphorylation activity was associated primarily with the
      particulate fraction. These data and the results of studies of [(14)C]trehalose
      uptake suggest that trehalose is transported into the cell as trehalose 6
      phosphate by a PEP:sugar phosphotransferase system. Cell extracts of other
      strains of B. popilliae were also found to produce [(14)C]sugar phosphate from
      [(14)C]trehalose and to have phosphotrehalase activity.

PMID- 4369402
TI  - Tritium sequence analysis of polyribonucleotides following periodate
      phosphomonoesterase degradation--analysis of nucleoside methylene dialdehydes
      derived from tetra-, penta-, and hexanucleotides.

PMID- 4369403
TI  - Tumor-specific membrane antigens in established cell lines from gliomas.

PMID- 4369404
TI  - Tumors in Gerbillinae: a literature review and report of a case.

PMID- 4369405
TI  - Type 2 hyperprolinemia: absence of delta1-pyrroline-5-carboxylic acid
      dehydrogenase activity.
AB  - triangle up(1)-Pyrroline-5-carboxylic acid dehydrogenase activity was measured
      radioisotopically in normal and type 2 hyperprolinemia fibroblasts. The type 2
      cells had no detectable activity over a range of reaction conditions whereas
      normal cells had easily measurable activity. This enzymatic defect accounts for
      the biochemical abnormalities in type 2 hyperprolinemia.

PMID- 4369406
TI  - TSH initiation of hormone secretion by rat thyroid lobes in vitro.

PMID- 4369407
TI  - Ultrasonic diagnosis in melanoma and retinoblastoma.

PMID- 4369409
TI  - Ultrastructural changes produced in Proteus vulgaris by a synergistic combination
      of colistin and sulphadiazine.

PMID- 4369411
TI  - Ultrastructural observations of anterior pituitary somatotrophs following
      pituitary portal vessel infusion of dibutyryl cAMP.

PMID- 4369410
TI  - Ultrastructural examination of various stages of amelogenesis in the rat
      following parenteral fluoride administration.

PMID- 4369408
TI  - Ultrastructural alterations of rat brain microglial cells and pericytes after
      chronic lead poisoning.

PMID- 4369412
TI  - Ultrastructural studies on tumours and cell cultures of the Harding--Passey mouse
      melanoma.

PMID- 4369413
TI  - Ultrastructural study of androgen-producing adrenocortical adenoma.

PMID- 4369414
TI  - Ultrastructural study of brain lesions produced in mice by the administration of
      Clostridium welchii type D toxin.

PMID- 4369415
TI  - Ultrastructure of polymorphic Mucor as observed by means of freeze-etching. II.
      Vegetative yeast form grown under anaerobic conditions.

PMID- 4369416
TI  - Ultrastructure of polymorphic Mucor as observed by means of freeze-etching. 3.
      Dormant sporangiospore.

PMID- 4369417
TI  - Ultrastructure of pure cultures of Physarum flavicomum. 1. Conversion of a
      plasmodium to microplasmodia and microsclerotia, and the process of slime
      secretion.

PMID- 4369418
TI  - Ultrastructure of the chamber angle after a short period of high intraocular
      pressure.

PMID- 4369419
TI  - Ultrastructure of the extended ribonucleic acid molecules from purified ribosomes
      of Rous sarcoma virus-induced mouse ascites sarcoma cells.

PMID- 4369420
TI  - Ultraviolet-enhanced reactivation of Herpes virus in human tumor cells.

PMID- 4369421
TI  - Untreated neonatal herpes simplex 2 meningitis without apparent neurologic
      damage.

PMID- 4369422
TI  - Unusual metastatic sites of colonic and rectal carcinoma: Report of four cases.

PMID- 4369423
TI  - Urinary excretion and cerebrospinal fluid concentration of cyclic adenosine-3',5'
      monophosphate in various neurological diseases.

PMID- 4369424
TI  - Use of benzoylated cellulose columns for the isolation of poly(adenylic acid)
      containing RNA and other polynucleotides with little secondary structure.

PMID- 4369425
TI  - Use of immune lymphocytes to detect expression of herpetic genome.

PMID- 4369426
TI  - Utilization of ascites plasma very low density lipoprotein triglycerides by
      Ehrlich cells.
AB  - Much of the lipid present in the ascites plasma in which Ehrlich cells grow is
      contained in very low density lipoproteins (VLDL). Chemical measurements
      indicated that triglycerides were taken up by the cells during in vitro
      incubation with ascites VLDL. When tracer amounts of radioactive triolein were
      incorporated into the ascites VLDL, the percentage uptakes of glyceryl tri[1
      (14)C]oleate and triglycerides measured chemically were similar. The cells also
      took up [2-(3)H]glyceryl trioleate that was added to VLDL, but the percentage of
      available (3)H recovered in the cell lipids was 30-40% less than that of (1 4)C
      from glyceryl tri[1-(1 4)C]oleate. This difference was accounted for by water
      soluble (3)H that accumulated in the incubation medium, suggesting that extensive
      hydrolysis accompanied the uptake of VLDL triglycerides. Radioactive fatty acids
      derived from the VLDL triglycerides were incorporated into cell phospholipids,
      glycerides, and free fatty acids, and they also were oxidized to CO(2).
      Triglyceride utilization increased as the VLDL concentration was raised. These
      results suggest that one function of the ascites plasma VLDL may be to supply
      fatty acid to the Ehrlich cells and that the availability of fatty acid to this
      tumor is determined in part by the ascites plasma VLDL concentration. Although
      Ehrlich cells incorporate almost no free glycerol into triglycerides,
      considerable amounts of [2-(3)H]glyceryl trioleate radioactivity were recovered
      in cell triglycerides. This indicates that at least some VLDL triglycerides were
      taken up intact. The net uptake of VLDL protein and cholesterol was very small
      relative to the triglyceride uptake, suggesting that intact triglycerides are
      transferred from the ascites VLDL to the Ehrlich cells and that hydrolysis occurs
      after the triglyceride is associated with the cells.

PMID- 4369427
TI  - Uveitis, episcleritis and conjunctivitis associated with Yersinia infection.

PMID- 4369428
TI  - Vacuolar transcellular channels as a drainage pathway for cerebrospinal fluid.
AB  - 1. Based on our ultrastructural investigations in monkeys, we report here a new
      concept as to the physiological mechanism of drainage of cerebrospinal fluid
      (c.s.f.) which would seem to bridge the gap between the two apparently opposing
      views of ;closed' and ;open' system.2. Our studies reveal the presence of an
      intact mesothelial lining of the arachnoid mater, including its villus-like
      projections and herniations into the dural sinus and its lacunae, adjacent cells
      being joined by tight junctions; in addition we have observed for the first time
      that many lining cells in the region of the superior sagittal sinus are
      characterized by unit membrane-bound, electron-optically empty giant vacuoles of
      several micrometres diameter. In one monkey with a fresh subarachnoid
      haemorrhage, many vacuoles were filled with plasma proteins and some contained
      intact blood corpuscles.3. Serial section analysis showed that the vacuoles were
      in fact invaginations from the basal aspect of the cell surface and were
      evidently in direct communication with the c.s.f. in the subarachnoid space. Some
      vacuoles in addition showed openings on their apical surface thus constituting
      transcellular channels or pores. Basal openings up to 3.5 mum and apical openings
      up to 2.3 mum were seen.4. It is postulated that vacuoles are stages in the
      formation of a dynamic system of transcellular pores which allow the bulk outflow
      of c.s.f. down a pressure gradient, and that the mesothelial vacuolation cycle,
      in providing the requisite number of transcellular pores across the mesothelial
      barrier at any time, is a controlling factor in the outflow of c.s.f. and in the
      maintenance of its fluid-pressure within the subarachnoid space.5. The basic
      similarity between the bulk flow of the aqueous humour and c.s.f. from the
      anatomically closed cavities of the anterior chamber and the subarachnoid space,
      respectively, is underlined.6. The present study provides further support for our
      hypothesis that the bulk outflow of fluid, via a dynamic system of transcellular
      pores formed by gradually enlarging membranous surface infoldings in a single
      cell, termed as giant vacuoles, is a fundamental biological process not hitherto
      described.

PMID- 4369430
TI  - Variability of sleep measures in normal subjects.

PMID- 4369429
TI  - Value of aortography in the diagnosis of congenital multicystic kidney.

PMID- 4369431
TI  - Vascular characteristics of unilateral acute renal failure in the dog. Assessment
      with vasodilators and antagonists to angiotensin and norepinephrine.

PMID- 4369432
TI  - Vascular intimal components: precursors of thrombosis.

PMID- 4369433
TI  - Vascular responsiveness of the in situ perfused dog pancreas.

PMID- 4369436
TI  - Viability of swine vesicular disease in carcases and faeces.

PMID- 4369434
TI  - Vasoactive intestinal peptide stimulation of adenylate cyclase and active
      electrolyte secretion in intestinal mucosa.
AB  - Vasoactive intestinal peptide (VIP), originally isolated from hog small
      intestinal mucosa, has been shown to cause small intestinal secretion. More
      recently, this peptide has been identified in the plasma and tumors of patients
      with the so-called "pancreatic cholera" syndrome. In order to explore the
      possible role of VIP in the pathogenesis of this syndrome, we examined the
      effects of this peptide and other hormones on the cyclic AMP levels, adenylate
      cyclase activity, and ion transport in in vitro preparations of ileal mucosa. In
      rabbit ileal mucosa, VIP (20 mug/ml) caused a prompt fivefold increase in cyclic
      AMP level, whereas nine other hormones, which have been postulated to cause
      intestinal secretion, failed to exert such an effect. Pentagastrin and glucagon
      also failed to increase cyclic AMP levels in canine ileal mucosa. An increase in
      mucosal cyclic AMP levels was observed at a VIP concentration of 0.1 mug/ml and
      appeared to be nearly maximal at 2.0 mug/ml. VIP (100 mug/ml) stimulated
      adenylate cyclase activity in a membrane preparation from rabbit ileal mucosa.
      Secretin (6.0 x 10(-5) M) failed to do so. When added to the serosal side of
      isolated rabbit ileal mucosa clamped in an Ussing chamber, VIP (2 mug/ml)
      increased short-circuit current (SCC) and caused net secretion of both Cl and Na.
      Net Cl secretion exceeded net Na secretion. These effects of VIP on mucosal
      cyclic AMP metabolism and ion transport are similar to those observed with
      cholera enterotoxin and certain prostaglandins. VIP was also tested with normal
      human ileal mucosa. At a concentration of 2 mug/ml it caused a fivefold increase
      in cyclic AMP level and an increase in SCC of the same magnitude as that caused
      by 5 mM theophylline. Addition of a second 2-mug/ml dose of VIP and addition of
      theophylline after VIP produced no further change in SCC. We conclude the VIP
      stimulates adenylate cyclase and active ion secretion in both rabbit and human
      ileal mucosa. This may be related to the pathogenesis of diarrhea in patients
      with the pancreatic cholera syndrome.

PMID- 4369435
TI  - Ventilation and sleep state in the new-born.
AB  - 1. Ventilation, oesophageal pressure and sleep state were measured in fourteen
      babies between 25 hr and 7 days of age.2. Trunk plethysmograph records showed
      that respiratory rate and minute volume were significantly higher in REM sleep
      than non-REM sleep. Tidal volume was not significantly altered.3. Tidal volume,
      respiratory rate and minute volume were all more variable in each baby in REM
      sleep, both on breath to breath analysis and over successive 20 sec periods.4.
      Major oesophageal peristaltic activity was observed in REM sleep only.5. In
      response to a sharp rise in P(O2) the tidal volume and minute volume fell
      significantly by the same proportion in both sleep states. Respiratory rate did
      not change significantly.

PMID- 4369437
TI  - Villous adenoma of the colon and rectum: an ultrastructural study.
AB  - The villous component of nine colonic polyps (three pure villous adenoma and six
      mixed adenomatous and villous adenomas) was studied by light and electron
      microscopy. Normal colonic mucosa was used for control. The predominant cell was
      an undifferentiated epithelial cell resembling those of the base of the crypts of
      normal colonic mucosa. A minority of these cells differentiated toward goblet
      cells and absorptive cells. Interdigitations of the plasma membrane with enlarged
      intercellular spaces were frequently observed, possibly related to the loss of
      water and electrolytes in some of these tumors, suggesting an analogy to renal
      tubular plasma membrane changes in kalliopenic nephropathy. Numerous membrane
      bound, inter and intracellular "inclusion bodies" representing degenerated
      lymphocytes and epithelial cell organelles were commonly found. Viral inclusions
      were not detected in this material. The possibility that the inclusion bodies
      observed in villous adenoma may represent lysosome-modified vesicles, secondary
      to absorption of protein and surface mucosubstances appears unlikely.

PMID- 4369439
TI  - Virus infection and incidence of respiratory disease: a serological study of four
      micro-organisms at a large beef-rearing farm.

PMID- 4369441
TI  - Viruses and the immune response.

PMID- 4369440
TI  - Virus-specific proteins associated with ribosomes of Krebs-II cells infected with
      encephalomyocarditis virus.

PMID- 4369438
TI  - Viral teratology.

PMID- 4369442
TI  - Vitamin D hormones. 2.

PMID- 4369444
TI  - Water pollution. Microbiology--detection, occurrence, and removal of viruses.

PMID- 4369443
TI  - Vitamin D hormones: 1.

PMID- 4369445
TI  - What is analgesia?

PMID- 4369446
TI  - Wilms's tumour--an improved prognosis. Report of 22 consecutive children seen
      from 1967-71.

PMID- 4369447
TI  - X-ray diffraction studies of DNA at reduced water contents.

PMID- 4369448
TI  - X-ray small angle scattering of human plasma high density lipoprotein LpA from
      HDL2: application of a new evaluation method.

PMID- 4369449
TI  - Xanthine oxidase deficiency: studies of a previously unreported case.

PMID- 4369450
TI  - 1,N6-etheno-2-aza-adenosine 3',5'-monophosphate: a new fluorescent substrate for
      cycle nucleotide phosphodiesterase.

PMID- 4369451
TI  - 1H nuclear magnetic resonance studies of thyrotropin releasing factor (TRF).

PMID- 4369452
TI  - 2',3'-Cyclic nucleotide 3'-phosphohydrolase activity in human brain tumours.

PMID- 4369453
TI  - 270 MHz proton magnetic resonance spectra of metallothionein.

PMID- 4369454
TI  - 3' End-group labeling and partial sequence determination of
      oligodeoxynucleotides.

PMID- 4369455
TI  - 5'-Terminal nucleotide sequences of the double-stranded RNA of silkworm
      cytoplasmic polyhedrosis virus.

PMID- 4369456
TI  - 6-O-methyl-D-glucosamine in lipopolysaccharides of Rhodopseudomonas palustris
      strains.

PMID- 4369457
TI  - 8 alpha-substituted flavins of biological importance.

PMID- 4369458
TI  - On the hypothalamic regulation of the adenohypophysial gonadotropic function.

PMID- 4369459
TI  - Symptomatology of early maturing girls.

PMID- 4369460
TI  - [Clinical aspects of constitutional delay of maturation (author's transl)].

PMID- 4369461
TI  - Probable sites for estrogen receptors in brain and pituitary.

PMID- 4369462
TI  - [Erections in sleep and sexuality (author's transl)].

PMID- 4369463
TI  - (R,S)-2,3-epoxypropyl ethers and glycosides of D-glucopyranose.

PMID- 4369464
TI  - c-AMP phosphodiesterase activity during growth and differentiation in
      Blastocladiella emersonii.

PMID- 4369465
TI  - p-Nitrophenylphosphatase in denervated muscle.

PMID- 4369466
TI  - [A case of reversible erythroblastopenia due to thiamphenicol].

PMID- 4369467
TI  - [A case of spinal chloroma revealing acute leukemia].

PMID- 4369468
TI  - [A rare developmental disorder of the proximal femur end].

PMID- 4369469
TI  - [A summary of our study of temperature-sensitive mutants of SV 40 (author's
      transl)].

PMID- 4369470
TI  - [Abnormalities of phosphorus and calcium metabolism in the course of Basedow's
      disease].

PMID- 4369471
TI  - [Abnormalities of spermatogenesis in a mutant rat].

PMID- 4369472
TI  - [Acetylated corticotropin suppression of age dependant increase in the weight of
      the ovaries in mice].

PMID- 4369473
TI  - [Activity and subcellular localization of the enzyme adenyl cyclase in the flight
      muscle of Locusta migratoria (author's transl)].

PMID- 4369475
TI  - [Activity of protocollagen proline hydroxylase in the chick embryo liver as a
      function of age].

PMID- 4369474
TI  - [Activity of glucose-6-phosphate dehydrogenase, transketolase and glucose-6
      phosphatase in rat liver with different levels of corticosteroids and ACTH].

PMID- 4369476
TI  - [Acute Klebsiella pneumonia (author's transl)].

PMID- 4369477
TI  - [Adenomatosis of the lungs].

PMID- 4369478
TI  - [Administration of a diphosphonate in urinary calculi prevention].

PMID- 4369479
TI  - [Adrenal cortex and avitaminosis A: the influence of deficiency on the response
      to various experimental aggressions].

PMID- 4369480
TI  - [After care of treated tumor patients. Indication and efficacy of follow-up
      examination in Hodgkin's disease from the radiotherapeutic view-point].

PMID- 4369482
TI  - [An attempt to define radicular and pseudoradicular syndromes (author's transl)].

PMID- 4369481
TI  - [An aspect of fibrous dysplasia (author's transl)].

PMID- 4369483
TI  - [An evaluation of the 99mTc-Sn-polyphosphate or 99mTc-Sn-pyrophosphate
      scintigraphy for the detection of bone metastases from prostatic carcinoma
      (author's transl)].

PMID- 4369484
TI  - [Analysis of steroid hormones by gas-liquid chromatography. 17-Ketosteroids,
      pregnanediol and pregnanetriol in the urine (author's transl)].

PMID- 4369485
TI  - [Angiotensin test in the diagnosis of vasorenal hypertension].

PMID- 4369486
TI  - [Anti-inflammatory treatment of rheumatoid polyarthritis].

PMID- 4369487
TI  - [Antibody response in subjects vaccinated with a recall dose of the Sabin or Salk
      type vaccine].

PMID- 4369489
TI  - [Apocrine nevus. Study of 2 cases].

PMID- 4369488
TI  - [Antigenic structure of B. pertussis and its relationships to the conditions of
      strain circulation. II. The serological polymorphism of B. pertussis strains
      isolated from sick children and experimentally].

PMID- 4369490
TI  - [Appraisal and supervision of fees for various services in private and public
      hospitalization].

PMID- 4369491
TI  - [Approach to prognosis of hepatic schistosomiasis caused by Schistosoma mansoni].

PMID- 4369492
TI  - [Apropos of 25 primary cancers of the liver].

PMID- 4369493
TI  - [Bacterial ornithine lipids].

PMID- 4369494
TI  - [Behavior of silicic acid in live nature].

PMID- 4369496
TI  - [Benign duodenal tumors. Radiological and endoscopic correlations].

PMID- 4369495
TI  - [Benign and malignant soft-tissue neoplasms].

PMID- 4369498
TI  - [Biochemical properties of apathogenic Corynebacteria of human origin].

PMID- 4369499
TI  - [Body growth, skeletal age and size of the femoral epiphysis in children with
      Legg-Calve-Perthes disease on the territory of the East Bohemian Region].

PMID- 4369497
TI  - [Biochemical mechanisms in inducing of coagulation by collagen (author's
      transl)].

PMID- 4369500
TI  - [Carbohydrate metabolism of the lens depending on age. IV. Growth curves of
      enzyme activities and substrate concentrations of bovine lenses (author's
      transl)].

PMID- 4369502
TI  - [Certain methodological problems of an approach to the study of the biology of
      gliomas].

PMID- 4369501
TI  - [Carcinoidsyndrome due to anaplastic carcinoma of the pancreas (author's
      transl)].

PMID- 4369503
TI  - [Change in the ultrastructure of B. pertussis cultivated on different media. I.
      An electron microscopic study of B. pertussis during passage and storage on
      Bordet-Gengou medium].

PMID- 4369504
TI  - [Changes in lipid metabolism in rats during chronic inhalation of quartz dust].

PMID- 4369505
TI  - [Circadian organization of lipid metabolism in healthy subjects].

PMID- 4369506
TI  - [Circulating interferon in chickens inoculated with Rous viruses. Action of
      corticoids].

PMID- 4369508
TI  - [Clinical and biochemical aspects of virilizing adrenal tumors].

PMID- 4369507
TI  - [Classification of hyperlipoproteinemias].

PMID- 4369509
TI  - [Clinical aspects of tumors in childhood].

PMID- 4369510
TI  - [Clinical course and morphology of nodular adenomatosis of the lungs].

PMID- 4369511
TI  - [Clinical pathology of skin- and soft-tissue neoplasms].

PMID- 4369512
TI  - [Clinical picture of the F.P. Weber syndrome].

PMID- 4369513
TI  - [Clostridium perfringens. 2. S-form and R-form antigens].

PMID- 4369514
TI  - [Comments on the article "Prognosis of operated juvenile bone cyst in the
      roentgen picture" (Fortschritte Roentgenstrahlen 117 (1972) 52)].

PMID- 4369515
TI  - [Comparative studies on parenteral and nonparenteral immunization against canary
      pox].

PMID- 4369516
TI  - [Comparative study on quantitative determination of mixtures of analgesics. 1.
      Studies on selectivity of volumetric analysis procedures].

PMID- 4369517
TI  - [Conception and systematics of clinical follow-up therapy of mammary carcinoma
      (author's transl)].

PMID- 4369518
TI  - [Constrictive endocardial fibrosis or endo-myocardial fibrosis].

PMID- 4369519
TI  - [Coronary disease in Ivory Coast. Clinical, diagnostic and epidemiological
      aspects. Apropos of 75 cases].

PMID- 4369520
TI  - [Cortisolemia and pregnancy].

PMID- 4369521
TI  - [Cortisone psychoses].

PMID- 4369522
TI  - [Cryoglobulins, macroglobulins and the Gougerot-Sjogren syndrome. Treatment with
      chlorambucil and cyclophosphamide].

PMID- 4369524
TI  - [Current trends in the therapy of arteriosclerotic disease].

PMID- 4369523
TI  - [Crystallization inhibitory substances in urine and kidney calculi].

PMID- 4369525
TI  - [Cutaneous and rectosigmoid cavernous hemangiomas. Bean's syndrome].

PMID- 4369526
TI  - [Cyclic AMP].

PMID- 4369527
TI  - [Cytochrome oxidase activity in various rat organs following 200 Rad whole-body
      60Co-irradiation].

PMID- 4369528
TI  - [Cytomegalic disease as a cause of abortion].

PMID- 4369529
TI  - [Cytomegalic ulcer in the caecum after renal transplantation (author's transl)].

PMID- 4369530
TI  - [Cytomegalovirus infections in infancy. Epidemiology--diagnosis--clinical
      aspects].

PMID- 4369531
TI  - [Demonstration of a specific fixation of radio-iodinated human chorionic
      gonadotropin (HCG I-125) in fragments of human placentas].

PMID- 4369532
TI  - [Demonstration of tumor-specific cellular immunity and blocking serum factors in
      children with neuro- and nephroblastoma using a new in-vitro test (Leukocyte
      adherence inhibition)].

PMID- 4369533
TI  - [Determination by gas chromatography of the seven principal urinary oestrogens at
      the end of gestation (author's transl)].

PMID- 4369534
TI  - [Diagnosis, surgical and radiotherapeutic treatment of malignant tumors of the
      upper jaw].

PMID- 4369535
TI  - [Diagnostic and therapeutic problems of alveolar cell carcinoma].

PMID- 4369536
TI  - [Diagnostic problems in hepatic schistosomiasis].

PMID- 4369537
TI  - [Differential diagnosis of hyperlipidemias and hypolipidemias in endocrinologic
      diseases].

PMID- 4369538
TI  - [Difficulties of remission induction treatment of acute myeloblastic leukemia].

PMID- 4369539
TI  - [Disappearance of the theta antigen under the influence of products modifying
      infralymphocytic cyclic AMP metabolism].

PMID- 4369540
TI  - [Disorder of fat metabolism in the liver caused by the administration of a
      culture of Proteus vulgaris of varying age].

PMID- 4369541
TI  - [Disorders of memory of the Korsakoff type and-of transitory evolution in a case
      of septal tumor. Anatomo-clinical study].

PMID- 4369542
TI  - [Drug-induced lipidosis: formation of myeloid bodies (author's transl)].

PMID- 4369543
TI  - [Effect of a selective inhibitor of ribosomal RNA synthesis on the antiviral
      action of interferon].

PMID- 4369544
TI  - [Effect of heat on secretion of growth hormone and on activity of the adrenal
      cortex of the rat].

PMID- 4369545
TI  - [Effect of increase of cyclic AMP on the growth of cultures of guinea pig
      keratinocytes of the epidermis and fibroblasts of the dermis].

PMID- 4369546
TI  - [Effect of ionizing radiation on boundary surfaces. Cyclic changes of
      electrophoretic characteristics of albumin and quartz after radiation with low
      doses of x-rays].

PMID- 4369547
TI  - [Effect of large doses of vitamin D3 on the sodium, potassium, calcium and water
      content of the aortic wall in broilers].

PMID- 4369548
TI  - [Effect of satellite microorganisms on the growth of Leptospira colonies].

PMID- 4369549
TI  - [Effects of angiotensin, norepinephrine and tyramine on rabbit aortic strips
      (author's transl)].

PMID- 4369550
TI  - [Effects of hormones and chemical mediators on some functional parameters of the
      rabbit heart. I. Effect of angiotensin II].

PMID- 4369551
TI  - [Endolymphatic lipiodol-P32 therapy in melanoma of the limbs during clinical
      stage 1].

PMID- 4369552
TI  - [Enormous tuberculum of the scaphoid bone].

PMID- 4369553
TI  - [Enzymatic characteristics of populations of mitochondria isolated from the
      telencephalon of the chicken during development].

PMID- 4369554
TI  - [Epidemiologic evaluation of the causative role played by pertussis in the
      etiology of respiratory tract diseases in children].

PMID- 4369555
TI  - [Epidemiology of rheumatoid arthritis].

PMID- 4369556
TI  - [Epstein-Barr virus antibodies after blood transfusion (author's transl)].

PMID- 4369557
TI  - [Estrogen receptors in breast cancers and endocrine therapy].

PMID- 4369558
TI  - [Etiology and clinical characteristics of occupational pathology in workers
      engaged in the mechanical processing of crystal].

PMID- 4369559
TI  - [Experiences in the treatment of hirsutism with antiandrogenic drugs].

PMID- 4369560
TI  - [Experimental and epidemiological study of lysozyme and lysozyme with ecmoline in
      influenza and other acute respiratory diseases].

PMID- 4369562
TI  - [Eye movements in darkness in the "isolated brain" cat].

PMID- 4369561
TI  - [Experimental atherogenesis in the Wistar rat].

PMID- 4369563
TI  - [Fibrocystic disease of the breast].

PMID- 4369564
TI  - [Findings of viruses among foreign adopted children].

PMID- 4369565
TI  - [First results of comparative tests for sulfite-reducing Clostridium in
      sterilized milk].

PMID- 4369566
TI  - [Fixation and memorization of peripheral pain].

PMID- 4369567
TI  - [Form of systemic lupus erythematosus (lupoid sclerosis) resembling multiple
      sclerosis].

PMID- 4369568
TI  - [Fructose-1,6-diphosphatase activity at different stages of liver
      carcinogenesis].

PMID- 4369569
TI  - [Functional criteria of internal membrane fractions from rat liver mitochondria.
      II. Submitochondrial particles disintegrated by ultrasonic treatment or phosphate
      buffer].

PMID- 4369570
TI  - [Further purification of Cl. perfringens hyaluronidase].

PMID- 4369571
TI  - [Gastric localization of multiple myeloma].

PMID- 4369573
TI  - [General diagnosis of the functional state of the hypothalamus].

PMID- 4369572
TI  - [Gastritis and inflammation of the gastric stump after gastrectomy for ulcer.
      Radiological and endoscopic detection].

PMID- 4369574
TI  - [Glucose-6-phosphatase activity in liver carcinogenesis and in transplantable
      murine hepatomas].

PMID- 4369575
TI  - [Glyco-regulation and pregnancy].

PMID- 4369576
TI  - [Growth hormone secretion and diabetic syndromes].

PMID- 4369577
TI  - [Growth of a transplantable mast-cell neoplasm in the mouse inhibited by
      vesicular stomatitis virus (author's transl)].

PMID- 4369578
TI  - [Hepatic involvement in Rendu-Osler disease].

PMID- 4369579
TI  - [Hepatoma: hemoperitoneum and hemothorax as initial symptoms. Study of 2 personal
      cases].

PMID- 4369580
TI  - [Heptaminol effect on the activity of adenylcyclase and phosphodiesterase].

PMID- 4369581
TI  - [Herpetic corneal diseases].

PMID- 4369582
TI  - [Hormonal glyco-regulation during pregnancy. Correlations of insulin, cortisol
      and somatomammotrophic chorionic hormone].

PMID- 4369583
TI  - [Hyperlipoproteinemia and fibrin stabilization using blood factor 13].

PMID- 4369584
TI  - [Hyperlipoproteinemias and their skin manifestations].

PMID- 4369586
TI  - [Identification by electron microscopy of corticotropic cells in piglets].

PMID- 4369585
TI  - [Hypoplasia of intrahepatic bile ducts and other forms of intrahepatic
      cholestasis in infancy (author's transl)].

PMID- 4369587
TI  - [Iliac crest biopsies in various forms of rickets].

PMID- 4369588
TI  - [Immobilization of African buffaloes within the foot-and-mouth disease campaign
      in Botswana].

PMID- 4369589
TI  - [Immunocytic reactions of the gastric mucosa during alcoholic cirrhosis].

PMID- 4369590
TI  - [Immunological determination of aqueous humor lipoproteins (author's transl)].

PMID- 4369591
TI  - [Importance of formatio reticularis mesencephali in experimental models of
      hypertension].

PMID- 4369592
TI  - [Indication for tonsillectomy with references to morbidity, length of stay and
      after care].

PMID- 4369593
TI  - [Induction of malignant neurogenic tumors in the offspring of Sprague-Dawley rats
      after transcutaneous application of N-ethyl-N-nitrosourea during pregnancy
      (author's transl)].

PMID- 4369595
TI  - [Interferon and interferon stimulation. New items in therapy of viral
      infections].

PMID- 4369594
TI  - [Insulinemia and pregnancy].

PMID- 4369596
TI  - [Intestinal duplications].

PMID- 4369597
TI  - [Intrarenal regulation of sodium excretion in hypertension].

PMID- 4369598
TI  - [Islet cell tumors with hypoglycemia. Surgical tactics and results].

PMID- 4369599
TI  - [Isolation of soluble glycoproteins form the basement membrane of the human
      glomerulus using collagenase].

PMID- 4369600
TI  - [Klippel-Tranaunay syndrome].

PMID- 4369601
TI  - [Laboratory tests for the determination of the anterior pituitary function].

PMID- 4369602
TI  - [Late results of surgical treatment of primary-multiple metachronous cancer of
      the rectum and uterus].

PMID- 4369603
TI  - [Late-appearing congenital adrenal hyperplasia. Apropos of 3 cases of 11 beta
      hydroxylase deficiency].

PMID- 4369604
TI  - [Lesions of the uterine cervix during oral contraception].

PMID- 4369605
TI  - [Light and electron optical studies on protein crystals and microtubules in yeast
      protoplasts].

PMID- 4369606
TI  - [Liver as a site of extrarenal erythropoietin production (author's transl)].

PMID- 4369607
TI  - [Liver diseases, caused by chickenpox virus, in children with leukemia].

PMID- 4369608
TI  - [Lymphosarcomas of the stomach. Diagnostic value of gastroscopy and gastric
      biopsy under direct vision].

PMID- 4369609
TI  - [Malabsorption syndrome with mesenteric lymph node cavitation and splenic
      atrophy. Apropos of a new anatomo-clinical case].

PMID- 4369610
TI  - [Malignant angiofibromatosis].

PMID- 4369611
TI  - [Malignant giant-cell tumor of soft tissues. Case report].

PMID- 4369612
TI  - [Malignant influenza. Histopathogenetic discussion of an anatomical case].

PMID- 4369614
TI  - [Manual therapy and internal medicine (author's transl)].

PMID- 4369613
TI  - [Mandibular metastases from hepatoma. Apropos of a new case and literature
      review].

PMID- 4369615
TI  - [Medical Teaching Association of the Paris Hospitals (1907-1974)].

PMID- 4369616
TI  - [Metabolism of L-cystathione in tissue of brain glial tumors].

PMID- 4369617
TI  - [Method of extraction and fractionation of brain tissue phosphoinositides].

PMID- 4369618
TI  - [Methods of evaluating psychopharmacological agents experimentally].

PMID- 4369619
TI  - [Microcrystalline arthropathies (gout and pseudo-gout)].

PMID- 4369620
TI  - [Mixed mesodermal tumor of the uterine corpus in a 4-year-old girl].

PMID- 4369622
TI  - [Mononeuropathies of the leg and lesions of the lumbosacral plexus (author's
      transl)].

PMID- 4369621
TI  - [Modified cytochrome oxidase].

PMID- 4369623
TI  - [Morphology and ultrastructure of Wilms' tumor in children].

PMID- 4369624
TI  - [Multiple intercostal neurofibroma in a central form of neurofibromatosis (v.
      Recklinghausen's disease)].

PMID- 4369625
TI  - [Nasal bone osteoma and hyperostosis of the external auditory canal].

PMID- 4369626
TI  - [Neuro-psychic manifestations of hypoglycemia. Apropos of a case of malignant
      insulinoma].

PMID- 4369627
TI  - [Neurological complications in Paget's disease of spine].

PMID- 4369628
TI  - [Neurological signs of chronic renal insufficiency].

PMID- 4369629
TI  - [Neurophysiologic evaluation of functioning number of motor units in soleus
      muscle of the mouse during aging (preliminary results)].

PMID- 4369630
TI  - [New data on the metabolism and mechanism of action of vitamin D].

PMID- 4369631
TI  - [Oral immunization with vaccinia-virus against mouse-pox (author's transl)].

PMID- 4369632
TI  - [Orbital phlebography (author's transl)].

PMID- 4369633
TI  - [Osseous metastases of chemodectomas of the carotid body].

PMID- 4369634
TI  - [Osseous metastases revealing primary hepatic cancer].

PMID- 4369635
TI  - [Our studies in the treatment of exudative pleuritis].

PMID- 4369636
TI  - [Papilloma of the nasal and sinus cavities (author's transl)].

PMID- 4369637
TI  - [Pathomorphology of breast carcinoma].

PMID- 4369638
TI  - [Pathomorphology of infectious nervous system diseases].

PMID- 4369639
TI  - [Perfusion scans of the lung using 131xenon gas and 99mtechnetium particles. A
      comparison of the quantitative and morphological results (author's transl)].

PMID- 4369640
TI  - [Physiology of insulin secretion. 1. The energetic point of view].

PMID- 4369641
TI  - [Pion beam (pi) for biological and medical uses at the Swiss Institute of Nuclear
      Studies (SIN)].

PMID- 4369642
TI  - [Planning of dosimetry on the pion beam piE3 as preliminaries of biological
      experiments and medical applications].

PMID- 4369643
TI  - [Plastic surgery of skin in syndactylia].

PMID- 4369644
TI  - [Pneumopathies caused by hypersensitivity (farmer's lung and bird breeder's
      lung). Apropos of 2 cases in children].

PMID- 4369645
TI  - [Poisoning by acetonitrile. A lethal case].

PMID- 4369647
TI  - [Possibilities of drug therapy in brain tumors of childhood].

PMID- 4369646
TI  - [Polygraphic studies on sleep in adolescent drug addicts].

PMID- 4369648
TI  - [Possibilities of the development of the daily cost system].

PMID- 4369649
TI  - [Post-traumatic pulmonary haematomas and pneumatocoeles (author's transl)].

PMID- 4369650
TI  - [Pregnanetriolone excretion after stimulation with ACTH as a test on presumably
      heterozygous carriers of a 21-hydroxylase-deficiency (author's transl)].

PMID- 4369651
TI  - [Preoperative irradiation of Wilms' tumor].

PMID- 4369652
TI  - [Prevention of the manifestation of diabetes mellitus through dietetic and drug
      measures. 1. Theoretical and clinical aspects with reference to the insulin
      findings in the peripheral venous blood].

PMID- 4369653
TI  - [Problems and treatment of recurrent herpes simplex].

PMID- 4369654
TI  - [Proceedings: Long-term treatment of osteoporosis using sodium fluoride and
      vitamin D3].

PMID- 4369655
TI  - [Proceedings: Regulation of aldosterone secretion in patients without kidneys].

PMID- 4369656
TI  - [Prolonged treatment of severe hypoglycemia with diazoxide].

PMID- 4369657
TI  - [Protection afforded by hybrid cells against the inoculation of the parental
      tumour line (author's transl)].

PMID- 4369658
TI  - [Radiation-dosimetry studies after endolymphatic radionuclide therapy].

PMID- 4369659
TI  - [Radiotherapy of central nervous system neoplasms in childhood].

PMID- 4369660
TI  - [Reconsideration of Bartter's syndrome. Apropos of a new case].

PMID- 4369661
TI  - [Recurrent hydarthrosis of the knee (lipiodol intrajoint) (author's transl)].

PMID- 4369662
TI  - [Regression of the clinical signs of chronic subdural hematoma].

PMID- 4369663
TI  - [Research on the role of membrane phenomena in secretion of renin].

PMID- 4369664
TI  - [Respiratory diseases caused by asbestos].

PMID- 4369665
TI  - [Results of an inquiry into the types of packed meat and their microbiological
      requirements].

PMID- 4369666
TI  - [Results of 6 months of detection and prevention of congenital toxoplasmosis in
      the maternity ward of the Hopital Lariboisiere].

PMID- 4369667
TI  - [Review on internal medicine, 1973--nephrology. 5. The renin-angiotensin system
      (author's transl)].

PMID- 4369668
TI  - [So-called multiple reticulohistiocytosis (dermatoarthropathic giant-cell
      reticulohistiocytosis)].

PMID- 4369669
TI  - [Somatomammotrophic chorionic hormone and glyco-regulation].

PMID- 4369671
TI  - [Specificity of hospital medical supervision in the field of agriculture].

PMID- 4369670
TI  - [Special radiation units and-or SI-units?].

PMID- 4369672
TI  - [Stability of different forms of the estradiol-receptor complex as a function of
      pH].

PMID- 4369673
TI  - [Steroid hormones of the adrenal cortex--their biochemistry and biology].

PMID- 4369674
TI  - [Studies about the influence of different viruses on the benzo(a)pyrene
      carcinogenesis (author's transl)].

PMID- 4369675
TI  - [Studies on platelet aggregation inhibitory agents (author's transl)].

PMID- 4369676
TI  - [Studies on the hypothalamic and corticoadrenal functions in males following
      cranial injuries].

PMID- 4369677
TI  - [Studies on the mechanisms of the acquired resistance to poxvirus infections in
      mice: in vitro experiment (author's transl)].

PMID- 4369678
TI  - [Study of the amniotic fluid and its current importance in obstetrics].

PMID- 4369679
TI  - [Study of the mucosa of ileocystoplasties and ileo-ureteroplasties. Preliminary
      note].

PMID- 4369680
TI  - [Study of the nosological and pathological aspects of endogenous "pellagra". (A
      clinico-biological case)].

PMID- 4369681
TI  - [Succinocytochrome c-reductase and cytochrome c-oxidase in the brain of the rat
      during development].

PMID- 4369682
TI  - [Suitability of the immune adherence reaction (IAR) for the determination of
      antibodies against equine rhinovirus 1 in equine blood sera].

PMID- 4369683
TI  - [Suppression of the hormonal secretion of the thyroid gland of the dog in vitro
      by inhibitors of prostaglandin synthesis].

PMID- 4369684
TI  - [Surgical treatment of peripheral nerve lesions].

PMID- 4369685
TI  - [Systematic error in the determination of bone mineral equivalents by absorption
      measurements of monochromatic beams (author's transl)].

PMID- 4369686
TI  - [Systematic errors during radiological determinations of bone mineral content
      (author's transl)].

PMID- 4369687
TI  - [Systems of fixing daily prices and duration of stay].

PMID- 4369688
TI  - [Temperature sensitive mutants of herpes simplex virus (author's transl)].

PMID- 4369689
TI  - [Temperature sensitive mutants of polyoma virus and cell transformation (author's
      transl)].

PMID- 4369690
TI  - [Temperature-sensitive mutants of DNA tumor viruses (author's transl)].

PMID- 4369691
TI  - [Temperature-sensitive mutants of SV 40 (author's transl)].

PMID- 4369692
TI  - [The effect of angiotensin II on the composition of free fatty acids in blood
      plasma in rabbits].

PMID- 4369694
TI  - [The electromyogram in the evaluation of traumatic nerve lesions].

PMID- 4369695
TI  - [The kidney as an endocrine organ. I. Clinical significance of plasma renin
      determinations].

PMID- 4369693
TI  - [The effect of contrast media on the myocardium during coronary arteriography
      (experimental studies of electrolyte metabolism, autoradiographs and electron
      microscopic autoradiographs). Paper I (author's transl)].

PMID- 4369696
TI  - [The mechanism of action of the endocrinologic system with special reference to
      adenyl cyclase].

PMID- 4369697
TI  - [The neuronal organization of the left celiac ganglion in cats].

PMID- 4369698
TI  - [The platelet release reaction (author's transl)].

PMID- 4369699
TI  - [The problem of oily contrast emboli (author's transl)].

PMID- 4369700
TI  - [The use of paramagnetic electron resonance in studies on healthy human enamel].

PMID- 4369701
TI  - [The value of radiological observations: apical pleural scarring (author's
      transl)].

PMID- 4369702
TI  - [The 50th anniversary of "La Semaine des Hopitaux"].

PMID- 4369703
TI  - [Toxicological studies of tuberactinomycin-N on rat kidney (author's transl)].

PMID- 4369704
TI  - [Treatment of scleroderma with unithiol].

PMID- 4369705
TI  - [Tubular phosphate transport in vitamin D resistant rickets].

PMID- 4369706
TI  - [Tumor problems and follow-up care of tumors (author's transl)].

PMID- 4369707
TI  - [Ultrastucture of blood platelets in two new-born with trisomy 21,
      thrombocythaemia and leukemic syndrome (author's transl)].

PMID- 4369708
TI  - [Unusual case of combined oculo-facial-digital syndrome].

PMID- 4369709
TI  - [Use of angiotnesin as a pharmacodynamic-phonocardiographic test substance for
      the diagnosis of mitral valve diseases].

PMID- 4369710
TI  - [Vascular myelopathies].

PMID- 4369711
TI  - [What is the physiopathological importance of glucagon secretion?].

PMID- 4369712
TI  - A case of atrial myxoma.

PMID- 4369713
TI  - A column procedure for the esterification of organic acids with diazomethane at
      the microgram level.

PMID- 4369714
TI  - A comparative study of some properties of chromatin from normal diploid and SV-40
      transformed human fibroblasts.

PMID- 4369715
TI  - A comparison of renin and erythropoietin levels in anephric man.

PMID- 4369716
TI  - A cytogenetic investigation of blood lymphocytes in chronic forms of virus
      hepatitis.

PMID- 4369717
TI  - A direct, stimulating effect of cyclic GMP on purified phosphoribosyl
      pyrophosphate synthetase and its antagonism by cyclic AMP.

PMID- 4369718
TI  - A fluorescent method for the demonstration of cyclic 3',5'-AMP phosphodiesterase
      activity in polyacrylamide gel.

PMID- 4369719
TI  - A highly sensitive in vitro bioassay for luteinizing hormone and chorionic
      gonadotropin: testosterone production by dispersed Leydig cells.

PMID- 4369720
TI  - A method for determination of saturated phosphatidylcholine.
AB  - Phosphatidylcholine preparations containing saturated and unsaturated molecular
      species were subjected to KMnO(4)-NaIO(4) oxidation in aqueous acetic acid, which
      left only disaturated species intact. After the oxidation, the remaining intact
      phosphatidylcholine was separated by thin-layer chromatography. The procedure
      could be used as a simple and rapid method for microdetermination of the
      saturated species in phosphatidylcholine preparations containing more than 0.1
      micro mole of the saturated species. The contents of the saturated species in
      native phosphatidylcholines obtained from rat lung tissue and washings by this
      procedure were 35.7% and 58.3%, respectively.

PMID- 4369721
TI  - A method for determination of the methylated constituents of transfer ribonucleic
      acid.

PMID- 4369722
TI  - A method for quantitative determination of the abnormal lipoprotein of
      cholestasis, LP-X.

PMID- 4369723
TI  - A new approach to the isolation of RNA-DNA hybrids and its application to the
      quantitative determination of labeled tumor virus RNA.

PMID- 4369724
TI  - A new form of acute conjunctivitis epidemic in Taiwan. A simultaneous outbreak of
      adenovirus type II and "acute hemorrhagic conjunctivitis" virus infections.

PMID- 4369725
TI  - A new form of beta-thalassemia trait.

PMID- 4369726
TI  - A new hypothesis for the evolution of biological electron transport.

PMID- 4369727
TI  - A new method for radionuclide imaging of acute myocardial infarction in humans.

PMID- 4369728
TI  - A potent interferon inducer derived from poly (7-deazainosinic acid).

PMID- 4369729
TI  - A rapid gas chromatographic-mass spectrometric method for prostaglandin analysis
      at picomole levels.

PMID- 4369731
TI  - A seroepidemiological study of herpes simplex virus.

PMID- 4369732
TI  - A spin-label study of the photosynthetic bacterium, Rhodospirillum rubrum;
      Reduction and regeneration of nitroxide spin-labels.

PMID- 4369733
TI  - A study of associated factors, including genital herpes, in Black women with
      cervical carcinoma in Johannesburg.

PMID- 4369734
TI  - A study of auditory evoked responses during sleep.

PMID- 4369735
TI  - A study of methods of identification and estimation of Lp(a) lipoprotein and of
      its significance in health, hyperlipidaemia and atherosclerosis.

PMID- 4369736
TI  - A study of pyruvate-induced inhibition in the dogfish lactate dehydrogenase
      system. Mechanistic comparison with the iodination of pyruvate.

PMID- 4369737
TI  - A study on cataplexy.

PMID- 4369740
TI  - Abrogation of resistance to bone marrow grafts by silica particles. Prevention of
      the silica effect by the macrophage stabilizer poly-2-vinylpyridine N-oxide.

PMID- 4369739
TI  - A thermodynamic characterisation of the cytochromes of chromatophores from
      Rhodopseudomonas capsulata.

PMID- 4369741
TI  - Acetolysis of dextran NRRL b1397. Preparation of trisaccharides containing (1
      leads to 2)- and (1 leads to 6)-alpha-D-glucose linkages.

PMID- 4369742
TI  - Achilles tendinitis and tenosynovitis. A diagnostic manifestation of familial
      type II hyperlipoproteinemia in children.

PMID- 4369743
TI  - Acrodermatitis enteropathica associated with low density lipoproteins deficiency.

PMID- 4369744
TI  - Action of alpha-1,6-glucan glucohydrolase on oligosaccharides derived from
      dextran.

PMID- 4369745
TI  - Action of peptides and other algesic agents on paravascular pain receptors of the
      isolated perfused rabbit ear.

PMID- 4369746
TI  - Activation of glycogenolysis in perfused rat livers by glucagon and metabolic
      inhibitors.

PMID- 4369747
TI  - Activation of lordosis in ovariectomized guinea pigs by free and esterified forms
      of estrone, estradiol-17 beta and estriol.

PMID- 4369748
TI  - Activation of pea leaf chloroplast sedoheptulose 1,7-diphosphate phosphatase by
      light and dithiothreitol.

PMID- 4369749
TI  - Activation of simian virus 40 by transfer of isolated chromosomes from
      transformed cells.

PMID- 4369750
TI  - Active site chloride binding in liver alcohol dehydrogenase.

PMID- 4369752
TI  - Acute effects of ozone on cat lungs. II. Structural.

PMID- 4369751
TI  - Active transport of iodide and other anions across the choroid plexus.
AB  - 1. An in vitro preparation of the frog choroid plexus was used to study
      mechanisms of anion transport.2. It was observed that, in the absence of
      electrochemical potential gradients, there were net fluxes of I(-), SCN(-),
      TcO(4) (-), and Br(-) across the plexus, from the ventricular to the serosal
      surface. The net flux of I(-) reached a maximum at a concentration of 250 muM.3.
      On the basis of competition effects it was concluded that the affinity of the
      transport process for anions was: ClO(4) > ReO(4) approximately BF(4) > SCN
      approximately SeCN > I > NO(3) > Br > Cl.4. Ouabain, oligomycin, phloretin and
      2,4-DNP inhibited the net transport of anions, but phlorrhizin, furosemide, 2,4,6
      trinitro-m-cresolate, reducing agents, and antithyroid agents did not. Ouabain
      and phloretin were only effective on the ventricular side of the preparation.5.
      Anion transport required the presence of both Na and K. The requirement for Na
      was specific, but Rb, and to a lesser extent Cs, could substitute for K. Na in
      either the ventricular or the serosal fluids could partially stimulate anion
      transport, but K was only effective in the ventricular solution.6. TcO(4) (-),
      SCN(-) and I(-) were accumulated within the choroidal epithelium from the
      ventricular fluid, but not from the serosal fluid. Accumulation was inhibited by
      ouabain and ClO(4) (-).7. The unidirectional influx of I(-) across the apical
      cell membrane was about an order of magnitude greater than the flux across the
      epithelium. This flux was inhibited by ClO(4) (-), ouabain, and Na-free
      solutions.8. These experiments suggest the following mechanism for anion
      transport across the plexus: anions are actively transported into the epithelium,
      by a ouabain sensitive, Na/K dependent pump located in the brush border membrane.
      The anions are accumulated within the epithelium, and, finally, they pass into
      the serosal fluid down their electrochemical potential gradient. Relations
      between anion transport, Na/K transport, and Na/K ATPases are discussed.

PMID- 4369753
TI  - Acute respiratory infections.

PMID- 4369754
TI  - Adenosine 3',5'-monophosphate in amniotic fluid from pregnancy complicated by
      hypertension.

PMID- 4369755
TI  - Adenosine 3':5'-monophosphate and hormone interrelationships in the mammary gland
      of the rat during pregnancy and lactation.

PMID- 4369756
TI  - Adenosine 3':5'-monophosphate dependent protein kinase isolated from rat
      Harderian gland.

PMID- 4369757
TI  - Adenosine 3':5'-monophosphate-dependent protein kinase and the stimulation of
      ovarian nuclear ribonucleic acid polymerase activities.

PMID- 4369758
TI  - Adenylate kinase from Pseudomonas denitrificans. I. Purification and antiserum
      inhibition.

PMID- 4369759
TI  - Adrenal cells in tissue culture. The effect of papaverine and amytal on
      steroidogenesis, respiration and replication.

PMID- 4369760
TI  - Adrenergic stimulation of phosphatidylinositol labelling in rat vas deferens.

PMID- 4369761
TI  - Adrenoceptors and bronchial asthma.

PMID- 4369762
TI  - Adrenocortical control of monoamine oxidase activity in the ground squirrel
      (Citellus citellus) during the winter.

PMID- 4369763
TI  - Adrenocorticotrophic and growth hormone secretion. Studies during
      pneumoencephalography.

PMID- 4369765
TI  - Affinity chromatography purification of diphtheria toxin.

PMID- 4369764
TI  - Aetiology of hyperthyroidism. II.

PMID- 4369766
TI  - Affinity of murine and human interferon for concanavalin A.

PMID- 4369767
TI  - Agonist and antagonist relationships in 1- and 8-substituted analogs of
      angiotensin II.

PMID- 4369768
TI  - Algesic actions of the polypeptides and other agents.

PMID- 4369769
TI  - Allergenic glucans from dermatophytes. I. Isolation, purification, and biological
      properties.

PMID- 4369770
TI  - An electron microscopy study of the effects on dibutyryl cyclic AMP on Chinese
      hamster ovary cells.

PMID- 4369771
TI  - An epidemiologic study of breast cancer.

PMID- 4369772
TI  - An epizootic of Sendai infection with mortality in a barrier-maintained mouse
      colony.

PMID- 4369773
TI  - An estrogen binding protein in the renal cytosol of intact, castrated and
      estrogenized golden hamsters.

PMID- 4369774
TI  - An extra species of lysine transfer ribonucleic acid in polyoma virus-transformed
      cells in tissue culture.

PMID- 4369775
TI  - An in-vitro bioassay for prolactin based on stimulation of casein synthesis by a
      dispersed cell preparation from mouse mammary gland.

PMID- 4369776
TI  - An intracellular alpha-D-glucan from Clostridium botulinum, type E.

PMID- 4369777
TI  - An isoenzyme of 5'-nucleotide phosphodiesterase and alpha-fetoprotein in human
      hepatic cancer patient sera.

PMID- 4369778
TI  - An ultrastructural study of alkaline phosphatase activity in normal and
      neoplastic human salivary glands.

PMID- 4369779
TI  - An unusual variant of Klippel-Trenaunay-Weber syndrome.
AB  - The association of soft tissue and bony overgrowth, varicose veins and port-wine
      nevus is known as Klippel-Trenaunay-Weber syndrome. An unusual case of a young
      woman with this syndrome is presented. In addition to the classic features she
      had face swelling, bilateral limb involvement and an infected cutaneous
      lymphangioma. No evidence of arteriovenous fistula was demonstrated. In contrast
      to an abnormal lymphatic system the deep veins of the limbs were normal.
      Unilateral lung lesions were demonstrated which have not been described
      previously in such cases.

PMID- 4369780
TI  - Analysis of the RNA of defective VSV particles.

PMID- 4369781
TI  - Androgen binding proteins in cock's tissues: properties of ear lobe protein and
      determination of binding sites in head appendages and other tissues.

PMID- 4369783
TI  - Angiotensin infusion test in the diagnosis of renal hypertension.

PMID- 4369782
TI  - Angioleiomyoma of the skin.

PMID- 4369784
TI  - Anterior interosseous nerve syndrome.

PMID- 4369785
TI  - Anti-C3d antiglobulin reagents. I. Characteristics of the anti-C3c and anti-C3d
      responses during hyperimmunization in rabbits.

PMID- 4369786
TI  - Antibiotic neurotoxicity. Laboratory and clinical study.

PMID- 4369787
TI  - Antibodies to Epstein-Barr virus-associated nuclear antigen in infectious
      mononucleosis.

PMID- 4369788
TI  - Antibody to prolyl hydroxylase from rat skin and its cross-reactivity with enzyme
      from other species.

PMID- 4369789
TI  - Antimicrobial therapy in children.

PMID- 4369790
TI  - Application of measurement and control of dissolved oxygen pressure to vaccine
      production.

PMID- 4369792
TI  - Aspects of continuous cultivation of spore-forming microbes from the group
      Bacillus thuringiensis.

PMID- 4369791
TI  - Application of serum alpha feto-protein assay in mass survey of primary carcinoma
      of liver. The Co-ordinating Group for the Research of Liver Cancer. People's
      Republic of China.

PMID- 4369793
TI  - Atherogenic and thrombogenic mosaic.

PMID- 4369794
TI  - Atherosclerosis as a pediatric problem.

PMID- 4369795
TI  - Atherosclerosis in the rhesus monkey fed three food fats.

PMID- 4369796
TI  - Attempts to demonstrate the interferon defense mechanism in cultured mosquito
      cells.

PMID- 4369797
TI  - Attitudes and behaviors of acute and chronic schizophrenic patients regarding
      ambulatory treatment.

PMID- 4369798
TI  - Audiologic evaluation in cochlear and eighth nerve disorders.

PMID- 4369799
TI  - Autonomous derivatives of estrogen-induced renal carcinomas and spontaneous renal
      tumors in the Syrian hamster.

PMID- 4369800
TI  - Avian myeloblastosis virus DNA polymerase: initiation of DNA synthesis and an
      associated ribonuclease.

PMID- 4369801
TI  - ATP-dependent calcium uptake by microsomal fractions of pig coronary artery and
      its dependence on bradykinin and angiotensin II.

PMID- 4369802
TI  - Baroreceptor activity and responsiveness to angiotensin in patients with chronic
      renal failure.

PMID- 4369803
TI  - Basic rest-activity cycle in the perception of the spiral after-effect; a
      sensitive detector of a basic biological rhythm.

PMID- 4369804
TI  - Bentonite flocculation test for amoebiasis.

PMID- 4369805
TI  - Biliary excretion in vivo of bile acids synthesized by hepatomas.

PMID- 4369806
TI  - Biliary infections and the chouce of antibiotics.

PMID- 4369807
TI  - Binding of spin-labeled local anesthetics to phosphatidylcholine and
      phosphatidylserine liposomes.

PMID- 4369808
TI  - Binding of steroids to progesterone receptor proteins in chick oviduct and human
      uterus.

PMID- 4369809
TI  - Biochemical and biophysical studies on cytochrome c oxidase. XVIII.
      Potentiometric titrations of cytochrome c oxidase followed by circular dichroism.

PMID- 4369810
TI  - Biochemical neuroendocrinology. I. Biosynthesis of thyrotropin releasing hormone
      (TRH) by organ cultures of mammalian hypothalamus.

PMID- 4369811
TI  - Biochemistry and psychiatry with special reference to psychopharmacology.

PMID- 4369812
TI  - Biogenic amine-containing neurons: biochemical mechanisms of synaptic
      transmission.

PMID- 4369813
TI  - Biologic and immunologic comparison of two HSV-2 variants: one an isolate from
      cervical tumor cells.

PMID- 4369814
TI  - Biosynthesis of cholinesterase in rabbit bone marrow cells in culture.

PMID- 4369815
TI  - Biosynthesis of glycolipids in virus-transformed cells.

PMID- 4369816
TI  - Biosynthesis of 1-alkyl-sn-glycero-3-phosphate via adenosine triphosphate:1-alkyl
      sn-glycerol phosphotransferase.

PMID- 4369817
TI  - Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral
      agents. 1,2 6. Bis-basic-substituted fluoranthenes.

PMID- 4369818
TI  - Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral
      agents. 5. Bis-basic ethers of anthraquinone and bisalkamine esters of
      anthraquinonedicarboxylic acids.

PMID- 4369819
TI  - Blastocystis hominis: axenic cultivation.

PMID- 4369820
TI  - BGM, a continuous cell line more sensitive than primary rhesus and African green
      kidney cells for the recovery of viruses from water.

PMID- 4369821
TI  - Calciferol and its relatives. XVII. Ring-A components for synthetic work on
      vitamin D3 and on model compounds.

PMID- 4369822
TI  - Calcitonin secretion in vitro. I. Preparation of monolayer C-cell cultures.

PMID- 4369825
TI  - Calibration of a cascade centripeter dust sampler.

PMID- 4369823
TI  - Calcium homeostasis and the patogenesis and management of hypercalcemic
      disorders.

PMID- 4369824
TI  - Calculated equilibria of phosphocreatine and adenosine phosphates during
      utilization of high energy phosphate by muscle.

PMID- 4369826
TI  - Carbon-13 magnetic resonance assignments of the repeat peptides of elastin and
      solvent delineation of carbonyls.

PMID- 4369827
TI  - Carbon-13 spin-lattice relaxation studies of intramolecular motion in lysine and
      a series of oligolysines.

PMID- 4369828
TI  - Carcinoid tumours and cylindromas of the tracheobronchial tree.

PMID- 4369829
TI  - Carcinoma of the breast in American Negro men.

PMID- 4369830
TI  - Carcinoma of Skene's gland associated with urethral diverticulum: a case report.

PMID- 4369831
TI  - Cataracts induced by surface active agents.

PMID- 4369832
TI  - Cell cycle dependent transcription of SV40 DNA in SV40-transformed cells.

PMID- 4369833
TI  - Cell fusion, using Sendai virus, to effect inter-species transfer of a cell
      associated parasite (Theileria parva).

PMID- 4369834
TI  - Cell surface modifications in virus-transformed cells--glycolipid changes in the
      NIL2 hamster cells.

PMID- 4369835
TI  - Cellular immunity to herpes simplex virus mediated by interferon.
AB  - Rabbit kidney cell monolayers infected with herpes simplex virus (HSV) were
      incubated with leukocytes from rabbits immunized with complete Freund's adjuvant.
      When the leukocytes were exposed to tuberculin purified protein derivative (PPD),
      viral replication and plaque formation were markedly inhibited. Similarly, when
      leukocytes from animals immunized with HSV were exposed to UV-inactivated HSV,
      viral replication was markedly inhibited. Exposure of leukocytes from unimmunized
      animals or animals immunized with incomplete Freund's adjuvant to UV-inactivated
      virus or PPD produced relatively little inhibition of viral replication.
      Examination of supernatant fluids from stimulated cultures revealed a soluble
      mediator that had the properties of interferon. Interferon production was
      detected within several hours after exposure of sensitized leukocytes to antigen.
      Supernatant fluids from as few as one sensitized leukocyte per 200 rabbit kidney
      cells inhibited HSV replication by over 90%. These findings support the concept
      that the cellular immune response to HSV consists of two phases: an
      immunologically specific antigen recognition phase, and a nonspecific effector
      phase that stops HSV spread by generating interferon.

PMID- 4369836
TI  - Central and reflex regulation of sympathetic vasoconstrictor activity to limb
      muscles during desynchronized sleep in the cat.

PMID- 4369837
TI  - Cerebral metastatic disease in childhood.

PMID- 4369838
TI  - Cerebrospinal fluid concentration of cyclic adenosine-3',5'-monophosphate and
      pneumoencephalography.

PMID- 4369839
TI  - Certain biochemical and ultrastructural features of the ventricular myocardium
      following cardiac denervation.

PMID- 4369840
TI  - Change in the pituitary-adrenal function of silver foxes during selection
      according to behavior.

PMID- 4369841
TI  - Changes in chromatin proteins during liver regeneration.

PMID- 4369842
TI  - Changes in conformation of stereocilia in hair cells of the rat spiral organ of
      Corti after 6-hydroxydopamine as revealed by scanning electron microscopy.

PMID- 4369843
TI  - Changes in the properties of the resident L virus in somatic cell hybrid lines.

PMID- 4369844
TI  - Characteristics of sodium flux from serosa to mucosa in rabbit ileum.
AB  - Sodium flux from serosa to mucosa, J(sm) (Na) in rabbit ileum in vitro has been
      studied as a function of applied electrical potential at equal sodium
      concentrations in the bathing solutions. The results indicate that J(sm) (Na)
      involves two pathways, a diffusional flux through a paracellular shunt pathway
      and a flux that is independent of applied potential and presumably involves a
      transcellular pathway. The latter pathway comprises approximately 25 % of J(sm)
      (Na) in Ringer's solution containing 10 mM glucose and 25 mM bicarbonate. It is
      stimulated significantly by theophylline unaffected by removal of glucose or
      addition of ouabain but is reduced to negligible values by anoxia, dinitrophenol,
      and replacement of all chloride and bicarbonate by isethionate. Thus this
      component of J(sm) (Na) has a number of characteristics consistent with
      involvement in a specific secretory process mediating an electrically neutral
      secretory transport of sodium plus anion from serosa to mucosa. In addition to
      stimulating this process, theophylline significantly reduced the permeability of
      the paracellular shunt pathway to sodium.

PMID- 4369845
TI  - Characteristics of the cyclic 3',5'-AMP formation in isolated ovarian follicles
      from PMSG-treated immature rats after stimulation in vitro with gonadotrophins
      and prostaglandins.

PMID- 4369846
TI  - Characterization and properties of progesterone-binding components in human
      endometrium.

PMID- 4369847
TI  - Characterization of a hormone receptor defect in the androgen-insensitivity
      mutant.

PMID- 4369848
TI  - Characterization of a normal, tissular antigen extracted from human colonic
      tumors.

PMID- 4369849
TI  - Characterization of defective interfering viral particles present in a population
      of pseudorabies virions.

PMID- 4369850
TI  - Characterization of multiplication of embryo-adapted avian encephalomyelitis
      virus in chick embryo brain cell cultures.

PMID- 4369851
TI  - Characterization of the active site structures of arginine kinase-substrate
      complexes. Water proton magnetic relaxation rates and electron paramagnetic
      resonance spectra of manganous-enzyme complexes with substrates and of a
      transition state analog.

PMID- 4369852
TI  - Characterization of the plasma lipoproteins of the genetically obese
      hyperlipoproteinemic Zucker fatty rat.
AB  - The plasma lipoproteins of the Zucker fatty rat were characterized with respect
      to lipid and apoprotein composition, and results were compared with those
      obtained from lean controls. Information on apoproteins was obtained from gel
      filtration experiments and electrophoresis on polyacrylamide gels. Very low
      density lipoproteins (VLDL) were increased several-fold in fatties, and 78% of
      their mass was triglycerides compared with 60% in the controls. Low density (LDL)
      and high density (HDL) lipoproteins were increased by a factor of 2, although
      their compositions were similar to those of the controls. Levels of apoVLDL,
      apoLDL, and apoHDL were five, two and two times higher, respectively, in the
      fatties, and the two most rapidly moving subunit peptides on polyacrylamide gels
      were disproportionately elevated in the apoproteins. The slower of these two
      bands was present in relatively greater amounts than the faster one in fatties.
      If the slower peptide is an activator of lipoprotein lipase, analogous to the
      comparable subunit peptides of human apolipoproteins, plasmas of fatties could
      contain up to 10 times more lipase activator activity than control plasma. This
      finding, and the fact that adipose tissue lipoprotein lipase activity of fatties
      was about 150% of controls, suggests that fatties have increased capacities for
      VLDL catabolism. We have previously shown that hepatic VLDL secretory rates are
      higher than normal in these animals. The increased capacity for catabolism may be
      a response to the altered secretory rates.

PMID- 4369853
TI  - Characterization of the rat apolipoproteins. I. The low molecular weight proteins
      of rat plasma high density lipoproteins.

PMID- 4369854
TI  - Characterization of vesicular stomatitis virus nucleocapsids. I. Complementary 40
      S RNA molecules in nucleocapsids.

PMID- 4369855
TI  - Chemical and physiological approaches to neuroendocrine mechanisms: attempts at
      integration.

PMID- 4369856
TI  - Chemical constituents of the digestive gland of the sea hare Aplysia californica.
      I. Importance of diet.

PMID- 4369857
TI  - Chemical evolution. XXII. The hydantoins released on hydrolysis of HCN oligomers.

PMID- 4369858
TI  - Chemistry and biological activity of vitamin D, its metabolites and analogs.

PMID- 4369859
TI  - Chemistry of the hypothalamic releasing factors--studies on structure-function
      relationships.

PMID- 4369860
TI  - Chlorophyll a and cytochrome c at a heptane-water interface.

PMID- 4369861
TI  - Cholera enterotoxin stimulation of cAMP in cultured adrenal tumor cells.

PMID- 4369862
TI  - Cholesterol metabolism in the Ehrlich ascites tumor.

PMID- 4369863
TI  - Chromatin interaction with oestradiol-receptor protein complex.

PMID- 4369864
TI  - Chromophobe adenoma masquerading as corticosteroid-responsive optic neuritis.

PMID- 4369865
TI  - Clearing factor lipase and its role in the regulation of triglyceride
      utilization. Studies on the enzyme in adipose tissue.

PMID- 4369866
TI  - Clofibrate reversal of platelet hypersensitivity in hyperbetalipoproteinemia.

PMID- 4369867
TI  - Closed circular DNAs with tandem repeats of a sequence from polyoma virus.

PMID- 4369868
TI  - Clostridial myonecrosis of the abdominal wall. Management after extensive
      resection.

PMID- 4369870
TI  - Clostridium perfringens type D epsilon prototoxin. Some chemical, immunological
      and biological properties of a highly purified prototoxin.

PMID- 4369869
TI  - Clostridium perfringens type C in hemorrhagic enterotoxemia of neonatal calves in
      Alberta.

PMID- 4369871
TI  - Collagen degradation in cultured keloid and hypertrophic scar tissue.

PMID- 4369872
TI  - Collagen synthesis by lathyrogen-treated 3T6 fibroblasts.

PMID- 4369873
TI  - Collagenase induced changes in the circular dichroism spectrum of collagen.

PMID- 4369874
TI  - Color-enhanced chest roentgenography: a feasibility report.

PMID- 4369875
TI  - Committee on Environmental Hazards. Noise pollution: neonatal aspects.

PMID- 4369876
TI  - Comparative sensitivity and resistance of some strains of Pseudomonas aeruginosa
      and Pseudomonas stutzeri to antibacterial agents.
AB  - A comparison has been made of the sensitivities to various antibiotic and non
      antibiotic substances of some strains of Pseudomonas aeruginosa and P. stutzeri,
      the latter including strains isolated from eye and other cosmetic products and
      from other sources. Whereas P. aeruginosa strains showed a high resistance to
      cetrimide and to benzalkonium chloride, the P. stutzeri strains were generally
      more sensitive to these and to chlorhexidine. The P. stutzeri strains were also
      more sensitive to the various antibiotics tested. The loss of the ability to
      transfer an R factor by two strains of P. aeruginosa caused no significant change
      in their drug sensitivity pattern.

PMID- 4369877
TI  - Comparative studies on the effect of adrenocorticotrophic hormone (ACTH) and
      pregnenolone-16alpha-carbonitrile (PCN) upon drug response and distribution in
      rats.

PMID- 4369879
TI  - Comparison of effects of locally infused angiotensin I and II on hand veins and
      forearm arteries in man: evidence for converting enzyme activity in limb vessels.

PMID- 4369878
TI  - Comparative study of several hypolipidemic agents related to clofibrate.

PMID- 4369880
TI  - Comparison of glucocorticoid cytoplasmic receptors from liver, Zajdela hepatoma
      and HTC cells.

PMID- 4369881
TI  - Comparisons between induced by water deprivation or chemical stimulation.

PMID- 4369882
TI  - Competitive binding assay for estradiol receptor using immobilized antibody.

PMID- 4369883
TI  - Computerized tomography of the brain.

PMID- 4369884
TI  - Conditions influencing inhibitors of the colony-stimulating factor (CSF).

PMID- 4369885
TI  - Conductometric evaluation of interactions of electrolytes with D-glucitol, D
      glucose, glycerol, D-mannitol, and sucrose.

PMID- 4369886
TI  - Congenital goiter due to maternal ingestion of iodide.

PMID- 4369887
TI  - Continuous lymphoid cell lines with characteristics of B cells (bone-marrow
      derived), lacking the Epstein-Barr virus genome and derived from three human
      lymphomas.
AB  - Three exceptional cell lines have been tested for the presence of the Epstein
      Barr virus genome by nucleic acid hybridization (complementary RNA.DNA) and
      Epstein-Barr virus-determined nuclear antigen tests. Two lines were derived from
      Swedish lymphoma cases and one from an African Burkitt-like lymphoma biopsy that
      was negative for Epstein-Barr virus DNA and the virus-determined nuclear antigen.
      All three lines apparently lacked the viral genome. Two of the three lines
      clearly had characteristics of B-cells (bone-marrow-derived).

PMID- 4369888
TI  - Control of uracil transport by cyclic AMP in E. coli.

PMID- 4369890
TI  - Correlation of (Na+--K+)-ATPase activity with growth of normal and transformed
      cells.

PMID- 4369889
TI  - Cooperative interactions between native and modified subunits of rabbit liver
      fructose 1,6-bisphosphatase.

PMID- 4369891
TI  - Correlation of pretreatment serum nonprotein-bound cortisol and total 17
      hydroxycorticosteroid values with survival in patients with prostatic cancer.

PMID- 4369892
TI  - Corticosteroid therapy. Updating of principles.

PMID- 4369893
TI  - Current problems in myocardial metabolism.

PMID- 4369894
TI  - Cushing's disease. Treatment by pituitary implantation of radioactive gold or
      yttrium seeds.

PMID- 4369895
TI  - Cyclic changes in oviductal morphology and residual cytoplasmic estradiol binding
      capacity induced by sequential estradiol--progesterone treatment of spayed Rhesus
      monkeys.

PMID- 4369896
TI  - Cyclic guanosine monophosphate: elevation in degenerating photoreceptor cells of
      the C3H mouse retina.
AB  - As a result of an early deficiency in cyclic nucleotide phosphodiesterase
      activity, guanosine 3',5'-monophosphate accumulates in retinal photoreceptor
      cells before they begin to degenerate. It is suggested that degeneration of the
      photoreceptor cells is related to an imbalance in their metabolism or function
      which is caused by the elevated levels of cyclic guanosine monophosphate.

PMID- 4369897
TI  - Cyclic AMP as a cell surface activating agent in Dictyostelium discoideum.

PMID- 4369898
TI  - Cyclic AMP regulates phosphorylation of three protein components of rat cerebral
      cortex membranes for thirty minutes.

PMID- 4369899
TI  - Cytidine 3',5'-monophosphate (cyclic CMP). II. Initiation of leukemia L-1210 cell
      growth in vitro.

PMID- 4369900
TI  - Cytogenetic study of primary tumors of chemical and viral origin in the golden
      hamster. Communication I. Karyotypic characteristics of tumors induced by the
      Rous sarcoma virus and by 7,12-dimethylbenzanthracene.

PMID- 4369902
TI  - Cytosol androgen receptor from kidney of normal and testicular feminized (Tfm)
      mice.

PMID- 4369901
TI  - Cytomegalovirus: Clinical virological correlations in renal transplant
      recipients.
AB  - One-hundred thirty-two renal transplant recipients were systematically screened
      for viral infections and the findings correlated with the clinical course. One
      hundred ten patients showed evidence of infection with herpesviruses and 89
      patients showed laboratory evidence of infection with cytomegalovirus (CMV)
      uncomplicated by bacterial infections or technical complications. Patients
      without viral infections were usually asymptomatic. After recovery and
      development of anti-viral antibodies, most patients were asymptomatic despite the
      persistence of viral excretion in the urine. In contrast, the onset of viral
      infections were almost always accompanied by a significant clinical illness
      characterized by fever, leukopenia, and renal malfunction. Of 89 patients with
      cytomegalovirus infections, 83 survived at least three months. In these patients,
      the fever appeared to be self-limited and resolution of the fever was accompanied
      by increases in anti-CMV antibody. Renal biopsies demonstrated typical rejection
      reactions in all the biopsied patients and renal malfunction usually responded to
      anti-rejection treatment. Six of the 89 patients with CMV infections died within
      a month of viral isolation. These patients could be distinguished from those who
      recovered by a decreased or absent antibody response to the virus, suppressed
      lymphocyte responses to mitogen in autochthonous blood, and absent histologic
      evidence of rejection in the renal allografts. Thus, two paradoxical responses to
      CMV infections are seen in transplant patients: In the relatively immunocompetent
      patient, the infection is associated with renal allograft rejection, a prompt
      antibody response to the virus, and recovery. The severely immunosuppressed
      patient cannot make an antibody response, does not exhibit allograft rejection as
      a cause of renal malfunction, he may be further immunosuppressed by the viral
      infection, and is susceptible to sequential opportunistic infections leading to
      death.

PMID- 4369903
TI  - Daily changes in concentration of pancreatic and serum insulin and of blood
      glucose during 5 days of treatment of rats with growth hormone, ACTH, cortisol,
      dexamethasone, and tolbutamide alone and in combinations.

PMID- 4369905
TI  - Day care for cancer patients.

PMID- 4369904
TI  - Daily rhythms of steroid and associated pituitary hormones in man and their
      relationship to sleep.

PMID- 4369906
TI  - Degradation of O-phosphohydroxylysine in rat liver. Purification and properties
      of 2-aminoadipic semialdehyde dehydrogenase.

PMID- 4369907
TI  - Demonstration of two immunologically distinct xenotropic type C RNA viruses of
      mouse cells.

PMID- 4369908
TI  - Deoxycholate-mediated cleavage of the protein of Sendai virus nucleocapsid
      derived from infected cells.

PMID- 4369909
TI  - Depression in infant monkeys: physiological correlates.

PMID- 4369910
TI  - Depression of viral interferon induction in cell monolayers by coal dust.

PMID- 4369912
TI  - Determinants and modification of adrenergic and vascular resistance in the
      kidney.

PMID- 4369911
TI  - Detection of tricuspid valve vegetations by echocardiography.

PMID- 4369913
TI  - Determination of leptophos, leptophos oxon, and a possible phenolic
      photoconversion metabolite in rapeseed grain.

PMID- 4369915
TI  - Dialysis schedule and peripheral neuropathy.

PMID- 4369914
TI  - Development of hCG sensitivity in the testis of the immature rat.

PMID- 4369916
TI  - Diazoxide, encorton and streptozotocin in the treatment of malignant betacytoma.

PMID- 4369917
TI  - Dibutyryl cyclic AMP and cytotoxic lymphocytes in Hashimoto's thyroiditis.

PMID- 4369918
TI  - Dietary modulation of beta cell adenylate cyclase activity.

PMID- 4369919
TI  - Differences between liver and hepatoma cells in their complements of adenosine
      3':5'-monophosphate-binding proteins and protein kinases.

PMID- 4369920
TI  - Differences between the integration of avian myeloblastosis virus DNA in leukemic
      cells and of endogenous viral DNA in normal chicken cells.
AB  - The nature of integrated viral DNA in normal and leukemic chicken cells has been
      studied by sequential nucleic acid hybridization procedures that localize the
      viral specific DNA in cellular DNA regions differing in reiteration frequency.
      First, DNA.DNA reassociation was employed to fractionate cellular DNA sequences
      according to their reiteration frequencies. Next, the DNA in each fraction was
      denatured, immobilized on nitrocellulose filters, and then hybridized with viral
      [(3)H]RNA. In normal cells, endogenous viral DNA appears to be associated with
      cell sequences reiterated 1200 times, and each integration unit appears to have a
      maximal size approximately equivalent to the 35S RNA subunit of the virion. In
      infected cells, additional viral sequences are found which reassociate as if they
      integrated adjacent to unique cellular DNA, or in tandem with endogenous viral
      DNA.

PMID- 4369921
TI  - Different effects of hormonal peptides and cyclic adenosine 3',5'-monophosphate
      on colonic transport in vitro.

PMID- 4369922
TI  - Different sensitivity of nuclear and microsomal NADH-cytochrome c reductase
      activities to thenoyltrifluoroacetone.

PMID- 4369923
TI  - Differential effects of an angiotensin II analogue on pressor and adrenal
      receptors in the rabbit.

PMID- 4369924
TI  - Diffusion and convection in normal and neoplastic tissues.

PMID- 4369925
TI  - Dilution kinetic studies of yeast populations: in vivo aggregation of galactose
      utilizing enzymes and positive regulator molecules.
AB  - By use of a selective medium containing ethidium bromide, population analyses of
      yeast galactose long-term adaptation mutants (gal3) in the process of
      deadaptation in the absence of galactose have been performed. The analysis of
      diploid strains homozygous for the gal3 locus but heterozygous for different
      combinations of the other mutant galactose loci, which thus have reduced amounts
      of the gene products of those loci, have demonstrated that, in addition to the
      two permease units determined in a previous study, a cell requires one complex of
      the Leloir pathway enzymes and two complexes specified by the Gal4 locus to be
      readily induced. From the consideration of these complexes as being aggregated
      molecules which are diluted out as units (i.e., if such a molecule were a dimer,
      it would not dissociate into monomers) during cell growth, the in vivo
      aggregation of these enzymes and the Gal4 gene product could be studied. The data
      indicate that the function of the Gal4 gene product is to activate a Leloir
      enzyme complex. It is postulated that the gal3 phenotype is the result of such
      strains' inability to actively synthesize an endogenous co-inducer which allows
      wild-type cells to be readily induced upon exposure to galactose.

PMID- 4369926
TI  - Direct involvement of vitamin D in the regulation of 25-hydroxycholecalciferol
      metabolism.

PMID- 4369927
TI  - Discharge planning: tentative program improves utilization.

PMID- 4369928
TI  - Dispersion and isolation of beating cells from adult rat heart.

PMID- 4369929
TI  - Distinct molecular species of interferons.

PMID- 4369930
TI  - Distribution patterns of hepatitis B antigen in the liver. Immunofluorescence
      studies.

PMID- 4369931
TI  - Distrubances in tryptophan metabolism after a single dose of aflatoxin B1 and
      chronic intoxication with carbon tetrachloride.

PMID- 4369932
TI  - Dominant lethal mutations induced in mice by orally administered ethyl
      methanesulfonate.

PMID- 4369934
TI  - Dosimetry of the SIN biomedical pion beam with tissue-equivalent ionization
      chambers.

PMID- 4369933
TI  - Dopaminergic inhibition of striatal cholinergic neurons: synergistic blocking
      action of gamma-butyrolactone and neuroleptic drugs.

PMID- 4369935
TI  - Dosimetry studies on the ethylation of mouse sperm DNA after in vivo exposure to
      (3H)ethyl metanesulfonate.

PMID- 4369936
TI  - Dynamics of functional and ultrastructural changes in the liver cells during the
      development of allyl alcohol necrosis.

PMID- 4369937
TI  - DNA strand breakage caused by dichlorvos, methyl methanesulphonate and
      iodoacetamide in Escherichia coli and cultured Chinese hamster cells.

PMID- 4369938
TI  - DNA strand scission by the antitumor protein neocarzinostatin.

PMID- 4369939
TI  - Early and late averaged electroencephalic responses at low sensation levels.

PMID- 4369940
TI  - Early and late viral-specific polyribosomal RNA in herpes virus-1 and -2-infected
      rabbit kidney cells.

PMID- 4369941
TI  - Early components of the averaged electroencephalic response to monaural and
      binaural stimulation.

PMID- 4369942
TI  - Early diagnosis of carcinoma of the bronchi with special reference to catheter
      biopsy.

PMID- 4369943
TI  - Early tendon transfer in upper extremity peripheral nerve injury.

PMID- 4369944
TI  - Editorial: Acute hemorrhagic conjunctivitis.

PMID- 4369945
TI  - Editorial: Hepatitis and herpesvirus.

PMID- 4369947
TI  - Editorial: The national Wilms tumor study. A progress report.

PMID- 4369946
TI  - Editorial: Neuroblastoma: possible viral aetiology?

PMID- 4369948
TI  - Editorial: Vaccination against whooping cough.

PMID- 4369949
TI  - Effect of "Aquasol A", vitamin A, and "Tween 80" on vesicular stomatitis virus
      plaque formation and on interferon action.

PMID- 4369950
TI  - Effect of cyclic nucleotides on the induction of ornithine decarboxylase in BHK
      cells by serum and insulin.

PMID- 4369951
TI  - Effect of cytochalasin B on hexose transport and glucose metabolism in pancreatic
      islets.

PMID- 4369952
TI  - Effect of energy-rich compounds on release of intracellular enzymes from human
      leukocytes and rat lymphocytes.

PMID- 4369953
TI  - Effect of flurazepam on sleep in the laboratory.

PMID- 4369954
TI  - Effect of glucagon, dibutyryl adenosine 3',5'-cyclic monophosphate and
      phosphodiesterase inhibitors on rat liver phosphorylase activity and adenosine
      3',5'-cyclic monophosphate levels.

PMID- 4369955
TI  - Effect of imipramine on adrenergic responses.

PMID- 4369956
TI  - Effect of morphine on serotonin release from myenteric plexus of the guinea pig.

PMID- 4369957
TI  - Effect of plasma protein concentration on glomerular and tubular function.

PMID- 4369958
TI  - Effect of propranolol on pituitary adrenal axis.

PMID- 4369959
TI  - Effect of prostaglandins on the velocity of the reaction between human renin and
      homologous renin substrate.

PMID- 4369960
TI  - Effect of subacute administration of human growth hormone on various serum lipid
      and hormone levels of hypercholesterolemic and normocholesterolemic subjects.

PMID- 4369961
TI  - Effect of testes removal and androgen replacement therapy on enzyme levels in
      hypothalamus and pituitary of frog (Rana esculenta).

PMID- 4369962
TI  - Effect of tissue injury on tumorigenesis induced by murine sarcoma virus
      (Harvey).

PMID- 4369963
TI  - Effect of IUD on uterine cyclic AMP and the activities of adenyl cyclase and
      phosphodiesterase during the oestrous cycle and early pregnancy in rats.

PMID- 4369964
TI  - Effect of 1,10-phenanthroline and desferrioxamine in vivo on prolyl hydroxylase
      and hydroxylation of collagen in various tissues of rats.

PMID- 4369965
TI  - Effects of acetylimidazole on the hydrolysis of fructose diphosphate and p
      nitrophenyl phosphate by liver fructose diphosphatase.

PMID- 4369966
TI  - Effects of dimethylsulfoxide on the E. coli gal operon and on bacteriophage
      lambda in vivo.

PMID- 4369967
TI  - Effects of drugs on the metabolism of bile acids.

PMID- 4369968
TI  - Effects of factors influencing the activity of the reticuloendothelial system on
      the half-life of labelled beta-lipoproteins. Preliminary report.

PMID- 4369969
TI  - Effects of growth phase and repair capacity on rejoining of ethyl
      methanesulfonate-induced DNA breaks in Escherichia coli.

PMID- 4369970
TI  - Effects of pituitary hormones and corticosterone on lipolysis in
      hypophysectomized rats.

PMID- 4369971
TI  - Effects of pokeweed mitogen, cholera toxin and prostaglandin E1 on immunoglobulin
      production and cyclic AMP levels in tonsillar lymphocytes.

PMID- 4369972
TI  - Effects of prostaglandin E1 and isoproterenol on cyclic AMP content of human
      fibroblasts modified by time and cell density in subculture.

PMID- 4369973
TI  - Effects of prostaglandins, cyclic AMP, seminal plasma, indomethacin, and other
      factors on oviposition in the Japanese quail, Coturnix coturnix japonica.

PMID- 4369974
TI  - Effects of tetrahydrocannabinols on cyclic AMP levels in rat brain areas.

PMID- 4369975
TI  - Effects of the combination of nicotinic acid and propranolol in very low doses on
      blood lipids in man.

PMID- 4369976
TI  - Effects of the 3',5'-cyclic phosphates of 2-methylthioadenosine, 2
      chloroadenosine and adenosine on platelet aggregation.

PMID- 4369978
TI  - Elastosis in tubular carcinoma of the breast.

PMID- 4369977
TI  - Effects of vitamin D3 on duodenal absorptive cells of chicks. An electron
      microscopic study.

PMID- 4369979
TI  - Electromyography and nerve conduction measurements.

PMID- 4369980
TI  - Electron microscope studies of the antileprosy drug B663 (clofazimine;
      Lamprenel).

PMID- 4369981
TI  - Electron microscopy of the pulmonary alveolar cells (granular pneumocytes) of
      normal and vagotomized amphibian (Bufo icterus icterus).

PMID- 4369982
TI  - Electron paramagnetic resonance of single crystal 15N-nitrosyl-57Fe-myoglobin.

PMID- 4369983
TI  - Electron paramagnetic resonance studies of the structure and metal ion exchange
      kinetics of vanadyl(IV) bovine carbonic anhydrase.

PMID- 4369984
TI  - Electrophoretic characterization of shuttling and nonshuttling small nuclear
      RNAs.

PMID- 4369985
TI  - Elevation of renal cyclic GMP concentrations and plasma lysosomal enzyme activity
      following cobalt treatment in rats.

PMID- 4369986
TI  - Elucidation of the exact sites of cleavage of tropocollagen by rheumatoid
      synovial collagenase: correlation of cleavage sites with fibril structure.

PMID- 4369987
TI  - Embryonic differentiation in the nucleoside triphosphatase activities of myosin
      from the fast, slow and cardiac muscles of chick.

PMID- 4369988
TI  - Endocrine disorders as a contributory factor to neoplasia in SJL-J mice.

PMID- 4369989
TI  - Endocrine evaluation in thalassemia major.

PMID- 4369990
TI  - Endocrine function in thalassemia major.

PMID- 4369991
TI  - Enhancement of Simian virus 40-induced transformation of Chinese hamster embryo
      cells by 4-nitroquinoline 1-oxide.

PMID- 4369992
TI  - Envelope proteins of vesicular stomatitis virions: accessibility to iodination.

PMID- 4369993
TI  - Enzymatic activation of Clostridium perfringens epsilon prototoxin and some
      biological properties of activated toxin.

PMID- 4369994
TI  - Enzymatic synthesis of 2-keto-3-deoxy-d-glucose from D-gluconate.

PMID- 4369995
TI  - Epidemiology as a field of practice.

PMID- 4369996
TI  - Episodic secretion of luteinizing hormone-releasing factor (LRF) in the human.

PMID- 4369997
TI  - Erythema annulare centrifugum coincident with Epstein-Barr virus infection in an
      infant.

PMID- 4369998
TI  - Erythrocyte phosphoribosylpyrophosphate concentrations in heterozygotes for
      hypoxanthine-guanine phosphoribosyltransferase deficiency.

PMID- 4369999
TI  - Erythrocytic galactokinase activity in neonatal and adult blood from various
      mammalian species.

PMID- 4370000
TI  - Erythroleukemia in two infant chimpanzees fed milk from cows naturally infected
      with the bovine C-type virus.

PMID- 4370001
TI  - Estradiol binding to rat corpora lutea during pregnancy.

PMID- 4370002
TI  - Estrogen receptor in normal and neoplastic mouse mammary tissues.

PMID- 4370003
TI  - Estrogen receptor interaction with the antitumor agent estradiol mustard.

PMID- 4370004
TI  - Estrogen receptors: physiology and clinical applications.

PMID- 4370005
TI  - Estrogenic regulation of uterine cyclic AMP metabolism.

PMID- 4370006
TI  - Evidence for a dual central role for angiotensin in water and sodium intake.

PMID- 4370007
TI  - Evidence for a structural interaction between ATP synthetase and cytochrome c
      oxidase in mitochondria.

PMID- 4370008
TI  - Evidence for a subcellular vesicular site of collagen prolyl hydroxylation.

PMID- 4370009
TI  - Evidence for common nucleotide sequences in the RNA subunits comprising Rous
      sarcoma virus 70 S RNA.

PMID- 4370010
TI  - Evidence for myocardial conversion of angiotensin I.

PMID- 4370011
TI  - Evidence for persistence of infectious agents in isolated human populations.

PMID- 4370012
TI  - Evidence for the T cell specificity of sodium periodate-induced lymphocyte
      blastogenesis.

PMID- 4370013
TI  - Evidence that adenosine 3', 5'-cyclic monophosphate is not involved in the growth
      response of prostate to androgens.

PMID- 4370014
TI  - Excretion of cyclic 3',5'-adenosine monophosphate in renal insufficiency and
      primary hyperparathyroidism after stimulation with parathyroid hormone.

PMID- 4370015
TI  - Experiences in computer audiometry (ECoG and ERA).

PMID- 4370016
TI  - Experimental encephalomyocarditis virus infection of pigs.

PMID- 4370017
TI  - Explants, transplants and implants of a cartilage and bone morphogenetic matrix.

PMID- 4370018
TI  - Extracellular current density analysis of responses in cerebellar cortex to mossy
      fiber activation.

PMID- 4370019
TI  - Fabry's disease in a black man without skin lesions.

PMID- 4370020
TI  - Fatty acids composition of very low density lipoprotein in psoriatic serum.

PMID- 4370021
TI  - Fibroma regression in relation to antibody and challenge immunity to bovine
      papilloma virus.

PMID- 4370022
TI  - Fibrous histiocytoma of the corneoscleral limbus.

PMID- 4370023
TI  - Filter assay for 1alpha, 25-dihydroxyvitamin D3. Utilization of the hormone's
      target tissue chromatin receptor.

PMID- 4370024
TI  - Fine structure of rat carotid body after 6-methylprednisolone treatment.

PMID- 4370025
TI  - Flank tumours in infants and children.

PMID- 4370026
TI  - Flash photolysis--electron spin resonance studies of the dynamics of photosystem
      I. 3. Temperature dependence of the decay of signal I.

PMID- 4370027
TI  - Fluoride uptake from prophylactic dentifrices. IV. In vitro fluoride uptake from
      two different types of abrasive dentifrices.

PMID- 4370028
TI  - Fractionation of plasma lipoproteins by density gradient centrifugation in swing
      out rotors.

PMID- 4370029
TI  - Fructose-1,6-diphosphatase deficiency: another enzyme defect which can present
      itself with the clinical features of "tyrosinosis".

PMID- 4370031
TI  - Functional classes of cells and their laminar distribution in monkey visual
      cortex.

PMID- 4370030
TI  - Functional arginyl residues as NADH binding sites of alcohol dehydrogenases.

PMID- 4370032
TI  - Functional organization of receptive fields in thalamic ventrobasal neurons
      examined by neuronal response to iterative electrical stimulation of skin.

PMID- 4370033
TI  - Further investigations of the expression of SV40-induced surface antigens
      subsequent to enzymatic treatment of transformed cells.

PMID- 4370034
TI  - Further studies of histone phosphorylation in the presence of inhibitors of DNA
      synthesis.

PMID- 4370035
TI  - Further studies on the accumulation and binding of androgen in rat epididymis.

PMID- 4370036
TI  - Further studies on the stimulation of prostatic ribonucleic acid polymerase by x
      5 alpha-dihydrotestosterone-receptor complexes.

PMID- 4370037
TI  - Gangliosides of bovine optic nerve.

PMID- 4370038
TI  - Gas chromatographic estimation of hydroxyproline.

PMID- 4370039
TI  - Gas-chromatographic detection of isethionic acid in pig heart.

PMID- 4370040
TI  - Gas-liquid chromatographic determination of vitamin D 2 in fortified full-cream
      dried milk.

PMID- 4370041
TI  - Gastric leiomyoblastoma.

PMID- 4370042
TI  - General proteolytic activity of highly purified preparations of clostridial
      collagenase.

PMID- 4370043
TI  - Generalized planar xanthomata associated with multiple myeloma and
      hyperlipoproteinemia.

PMID- 4370045
TI  - Genetic study on susceptibility of different mouse lines to ectromelia virus.

PMID- 4370044
TI  - Genetic expression of aryl hydrocarbon hydroxylase activity. Induction of
      monooxygenase activities and cytochrome P1-450 formation by 2,3,7,8
      tetrachlorodibenzo-p-dioxin in mice genetically "nonresponsive" to other aromatic
      hydrocarbons.

PMID- 4370046
TI  - Giant cell tumour associated with rheumatoid arthritis.

PMID- 4370047
TI  - Glomerular permeability to protein molecules--its possible structural basis.

PMID- 4370048
TI  - Glomus tumour. A review of 15 clinical cases.

PMID- 4370049
TI  - Glucocorticoid receptors. Characteristics, specificity, and ontogenesis in
      embryonic chick neural retina.

PMID- 4370050
TI  - Glucocorticoid-binding components in an irradiation-induced thymoma of the C57BL
      6J mouse.

PMID- 4370051
TI  - Glycogen metabolism in macrophages: effect of exogenous glycogen on glucogenesis
      in inflammatory exudate leukocytes and macrophages.

PMID- 4370052
TI  - Glycolytic enzymes in muscle of the pacific dolphin: role of pyruvate kinase in
      aerobic-anaerobic transition during diving.

PMID- 4370053
TI  - Gonadal androgen and sociosexual behavior of male mammals: a comparative
      analysis.

PMID- 4370055
TI  - Granular cell myoblastoma lentiginosis profusa.

PMID- 4370054
TI  - Gram-negative bacteria isolated from external eye infections.

PMID- 4370056
TI  - Granular cell myoblastoma of the Larynx.

PMID- 4370057
TI  - Granulated hydroxyapatite: preparation and chromatographic properties.

PMID- 4370058
TI  - Growth and body composition in intrauterine growth retardation (IUGR) before and
      during human growth hormone administration.

PMID- 4370059
TI  - Growth control in chick embryo fibroblasts; no evidence for a specific role for
      cyclic purine nucleotides.

PMID- 4370060
TI  - Haem-haem interactions in cytochrome aa3 during the anaerobic-aerobic transition.

PMID- 4370061
TI  - Hepatic artery ligation: adjunct in the management of massive hemorrhage from the
      liver.

PMID- 4370062
TI  - Hepatocellular cacinoma; prolonged survival following resection.

PMID- 4370063
TI  - Hepatocellular tolerance to carbon tetrachloride induced injury in the rat: a
      study of its nature and possible mode of evolution.

PMID- 4370064
TI  - Herpes simplex-genitalis virus nonvirion antigens and their implication in
      certain human cancers: unconfirmed.
AB  - The previously reported data on the existence of herpes simplex-genitalis virus
      nonvirion, neoantigens with distinctive properties, and on the presence of
      specific antibodies for these neoantigens only in the sera of specially
      hyperimmunized guinea pigs or of patients with certain types of cancer, could not
      be confirmed. Many factors that could have been responsible for the difference
      between the originally reported results and those recently obtained were
      carefully checked and investigated. The assumption that a mixture of two
      anticomplementary ingredients bound at least as much complement as the more
      anticomplementary component, and sometimes more, was found to be incorrect for
      the ingredients used in this work; the reverse was true. Previous failure to
      observe some of the strict requirements of the complement fixation test could
      account for some but not all of the unconfirmed previously reported data.
      Conclusions, based on the unconfirmed data, including those implicating these
      viruses in the etiology of certain human cancers, are therefore negated.

PMID- 4370065
TI  - Heterogeneity and unusually high affinity in the interactions of adenosine 3':5'
      monophosphate with specific binding proteins from liver and hepatoma cells.

PMID- 4370066
TI  - Heterogeneity in the methylation and 5' termini of Novikoff ascites hepatoma 5.8
      S ribosomal RNA.

PMID- 4370067
TI  - High-molecular-weight DNA associated with intracytoplasmic A-particle inclusions.

PMID- 4370068
TI  - Histochemical evidence of cyclic nucleotide phosphodiesterase in photoreceptor
      outer segments.

PMID- 4370069
TI  - Histochemical observations on the enzymes of chicken yolk sac membrane.

PMID- 4370070
TI  - Hormonal control of lipolysis in adipose tissue.

PMID- 4370071
TI  - Hormonal control of oestrogen receptor in uterus and receptivity for
      ovoimplantation in the rat.

PMID- 4370072
TI  - Hormone control of heme synthesis in cultures of human fetal liver cells.

PMID- 4370073
TI  - Host defense mechanisms against infection with influenza virus. I. Effect of
      sensitized spleen cells on infection in vitro.

PMID- 4370074
TI  - Housing for the disabled: a follow-up study.

PMID- 4370075
TI  - Human cataract and galactose metabolism.

PMID- 4370076
TI  - Hydatid cysts of the kidney. Simulating similar kidney lesions.

PMID- 4370077
TI  - Hypercalcaemia of neoplasia, parathyroid hormone and vitamin D: studies in
      parabiosis.

PMID- 4370078
TI  - Hypercholesterolemia and hypertriglyceridemia in children. A pediatric approach
      to primary atherosclerosis prevention.

PMID- 4370079
TI  - Hyperpigmentation on cortisone after adrenalectomy for primary aldosteronism.

PMID- 4370080
TI  - Hypnotic effects of L-tryptophan.

PMID- 4370081
TI  - Hypolipidemic drugs and lipoprotein metabolism.

PMID- 4370082
TI  - Hypothalamic control of secretion and release of prolactin.

PMID- 4370083
TI  - Identification of a poison in toxic scallops from a Gonyaulax tamarensis red
      tide.

PMID- 4370084
TI  - Identity of structure of ovine and bovine ACTH: correction of revised structure
      of the ovine hormone.

PMID- 4370086
TI  - Imidazole derivatives as inhibitors of cyclic nucleotide phosphodiesterases.

PMID- 4370085
TI  - IgM antibodies specific for Epstein-Barr virus in infectious mononucleosis
      without heterophil antibodies.
AB  - IgM antibodies specific for Epstein-Barr (E.B.) virus were demonstrable in all
      but one out of 46 patients diagnosed as having infectious mononucleosis wihout
      heterophil antibodies; cytomegalovirus aetiology was excluded. In all but two
      cases the highest titre was found in the first sample. In 21 patients a
      significant decrease was seen within a few weeks. IgG antibodies to E.B. virus,
      mostly remaining at a constant level, were demonstrable in all cases. IgM
      antibodies to E.B. virus were found in only five out of 300 controls.The results
      suggest that in a disease similar to infectious mononucleosis without heterophil
      antibodies testing of transient E.B. virus-specific IgM antibodies makes a rapid
      aetiological diagnosis possible and that in clinically well-defined cases viruses
      other than E.B. virus and cytomegalovirus are unlikely to be causal agents.

PMID- 4370087
TI  - Immunofluorescence staining for the diagnosis of herpes encephalitis.
AB  - Direct immunofluorescence staining for herpes simplex virus was applied to
      cryostat sections of 43 specimens removed at brain biopsy. Herpes antigen was
      found in 10 specimens and virus was isolated from them. Antigen was found in one
      specimen from which virus was not isolated. Two specimens from which virus was
      isolated gave equivocal fluorescence. Thirty specimens gave no fluorescence or
      live virus. Immunofluorescence provided a diagnosis in three hr compared with 24
      42 hr for virus isolation. Indirect immunofluorescence staining was applied to
      sections of brain removed at necropsy and fixed in formalin. Herpes antigen was
      found in sections of six of the 12 brains examined.

PMID- 4370088
TI  - Immunological phagocytosis: effect of drugs on phosphodiesterase activity.

PMID- 4370089
TI  - Immunopurification of phospholipase C (alpha-toxin) from Clostridium perfringens.

PMID- 4370091
TI  - Importance of age of host in detecting tumor-associated transplantation antigens.

PMID- 4370090
TI  - Implications of secretory immune system in viral infections.

PMID- 4370092
TI  - Importance of testes in induction of hyperplastic nodules, carcinomas, and
      cirrhosis of liver in A times C male rats ingesting 0.025 percent N-2
      fluorenyldiacetamide.

PMID- 4370093
TI  - In situ characterisation of photosynthetic electron transport in Rhodopseudomonas
      capsulata.

PMID- 4370094
TI  - In vivo study of mechanism of propranolol-induced blockade or neuromuscular
      transmission.

PMID- 4370095
TI  - In vivo subunit hybridization of succinic semialdehyde and 4-aminobutanal
      dehydrogenases from a Pseudomonas species.

PMID- 4370096
TI  - Increase in the amount of iodide released from the thyroid after perchlorate or
      carbimazole administration.

PMID- 4370097
TI  - Increased collagen synthesis in blood vessels of hypertensive rats and its
      reversal by antihypertensive agents.
AB  - Collagen synthesis is increased in the aortas, mesenteric arteries, and to a
      lesser extent, in the hearts of rats either made hypertensive with
      desoxycorticosterone acetate-salt or that are spontaneously hypertensive. Several
      markers of collagen biosynthesis were shown to be increased, including prolyl
      hydroxylase (EC 1.14.11.2; proline, 2-oxoglutarate dioxygenase), prolyl
      hydroxylase-related antigen, total collagen content, and the incorporation of
      [(3)H]proline into total protein and into collagen. The antihypertensive agents
      chlorothiazide and reserpine, when administered before the onset of hypertension
      in the rats treated with desoxycorticosterone acetate-salt, prevented or
      diminished the increase in collagen biosynthesis. When reserpine was given after
      the onset of hypertension, prolyl hydroxylase activity was decreased concomitant
      with the decrease in blood pressure. Treatment with reserpine is particularly
      effective in diminishing arterial prolyl hydroxylase activity.

PMID- 4370098
TI  - Induction of respiratory-deficient mutants in a "petite negative" yeast species
      Kluyveromyces lactis with N-methyl-N'-nitro-N-nitrosoguanidine.

PMID- 4370099
TI  - Infectious diseases in children with cancer.

PMID- 4370100
TI  - Infectious mononucleosis.

PMID- 4370101
TI  - Inferences from protein and nucleic acid sequences: early molecular evolution,
      divergence of kingdoms and rates of change.

PMID- 4370102
TI  - Influenza virus antigen in postencephalitic parkinsonism brain. Detection by
      immunofluorescence.

PMID- 4370103
TI  - Inhibition of human leucocyte collagenase by some drugs used in the therapy of
      rheumatic diseases.

PMID- 4370104
TI  - Inhibition of interferon action by plant lectins.

PMID- 4370105
TI  - Inhibition of membrane adenosine triphosphatase by alpha-tocopherol and its
      derivatives.

PMID- 4370106
TI  - Inhibition of platelet adherence to a collagen-coated surface by agents that
      inhibit platelet shape change and clot retraction.

PMID- 4370107
TI  - Inhibition of transport systems in cultured rat hepatoma cells by colcemid and
      ethanol.

PMID- 4370109
TI  - Inhibitors of inositol cyclase (D-glucose 6-phosphate-1L-myoinositol 1-phosphate
      cycloaldolase) from rat testis.

PMID- 4370108
TI  - Inhibitors against rabies virus present in normal rabbit sera.

PMID- 4370110
TI  - Inhibitory action of thyroid hormone of the activation of adenyl cyclase-cyclic
      AMP system by thyroid-stimulating hormone in human thyroid tissues from euthyroid
      subjects and thyrotoxic patients.

PMID- 4370111
TI  - Inhibitory effects of dibutyryl and cyclic AMP on the compound action potential
      in the frog (Rana pipiens) sciatic nerve.

PMID- 4370112
TI  - Inhibitory processes and interneuronal apparatus in motor cortex during sleep and
      waking. I. Background firing and responsiveness of pyramidal tract neurons and
      interneurons.

PMID- 4370113
TI  - Inhibitory processes and interneuronal apparatus in motor cortex during sleep and
      waking. II. Recurrent and afferent inhibition of pyramidal tract neurons.

PMID- 4370114
TI  - Intensive transfusion therapy in thalassemia major: an eight-year follow-up.

PMID- 4370115
TI  - Interaction between dehydroepiandrosterone, cyclic adenosine-3',5'-monophosphate
      and glucose-6-phosphate-dehydrogenase in normal and diseased subjects.

PMID- 4370116
TI  - Interaction of angiotensin peptides and of amino acids with p-nitrophenyl
      acetate.

PMID- 4370118
TI  - Interaction of manganous ion, substrates, and anions with arginine kinase.
      Magnetic relaxation rate studies of water protons and kinetic anion effects.

PMID- 4370117
TI  - Interaction of human serum high density lipoprotein apoprotein with
      phospholipids.

PMID- 4370119
TI  - Interaction of neomycin with phosphoinositide metabolism in guinea pig inner ear
      and brain tissues.

PMID- 4370120
TI  - Interactions between the prostaglandins and steroid hormones.

PMID- 4370121
TI  - Interferon production by lymphocytes from patients with systemic lupus
      erythematosus.

PMID- 4370122
TI  - Intravenous nutrition of newborn infants with lipid.

PMID- 4370125
TI  - Iodinated derivatives of adrenocorticotropic hormone. Preparation of iodinated
      alpha 1-24-ACTH with full hormonal activity.

PMID- 4370123
TI  - Intussusception as a complication of malignant neoplasm.

PMID- 4370126
TI  - Ion pair partition chromatography in the bioanalysis of alprenolol-(3H) and
      alprenolol metabolites.

PMID- 4370127
TI  - Is chloramphenicol the drug of choice for the treatment of enteric fever?
      Comparative studies on the effects of chloramphenicol, trimethoprim
      sulphametoxazole and beta-lactam antibiotics.

PMID- 4370128
TI  - Isolation and analysis of human plasma lipoproteins accumulating postrandial in
      an intermediate density fraction (d 1.006--1.019 g-ml).

PMID- 4370129
TI  - Isolation and characterization of bovine parainfluenza type 3 virus from cattle
      in Kenya.

PMID- 4370130
TI  - Isolation and fractionation of porcine peripheral lymphocytes.

PMID- 4370131
TI  - Isolation and identification of an O-(2-hydroxypropyl)-maltose from the faeces of
      rats fed with O-(hyroxypropyl)starch.

PMID- 4370132
TI  - Isolation and properties of protein component as activator for anthranilamide
      hydroxylation in rat liver.

PMID- 4370133
TI  - Isolation and protein pattern of eye lens fiber junctions.

PMID- 4370134
TI  - Isolation of infectious DNA from avian myeloblastosis virus transformed leukemic
      cells.

PMID- 4370135
TI  - Isolation of plasma membranes from normal and 1-beta-D arabinofuranosylcytosine
      transformed hamster embryo fibroblasts.

PMID- 4370136
TI  - Kinetic and molecular properties of lysine-sensitive aspartokinase. Factors
      influencing the lysine-mediated association reaction and their relationship to
      the cooperativity of lysine inhibition.

PMID- 4370137
TI  - Kinetic studies of the oxidation of ferrocytochrome c from horse heart and
      Candida krusei by tris(1,10-phenanthroline)cobalt(3).

PMID- 4370138
TI  - Kinetics and electron paramagnetic resonance spectra of vanadyl(IV)
      carboxypeptidase A.

PMID- 4370139
TI  - Labeling of the external surface of hamster and mouse fibroblasts with
      (14C)sialic acid.

PMID- 4370140
TI  - Laboratory test results altered by "The Pill".

PMID- 4370141
TI  - Lactate stimulation of renal cortical adenylate cyclase: a mechanism for
      erythropoietin production following cobalt treatment or hypoxia.

PMID- 4370142
TI  - Late field responses in optic tectum of the pigeon.

PMID- 4370143
TI  - Lead neuropathy and sickle cell disease.

PMID- 4370144
TI  - Letter to the editor: Differences between in vivo and in vitro actions of
      prostaglandins in corpus luteum: is there a paradox?

PMID- 4370145
TI  - Letter: Alcohol and alpha-lipoprotein cholesterol.

PMID- 4370147
TI  - Letter: Congenital mesoblastic nephroma.

PMID- 4370146
TI  - Letter: Assay for carcinoembryonic antigen.

PMID- 4370148
TI  - Letter: Diagnosis of insulinomas.

PMID- 4370149
TI  - Letter: Experimental infection of a horse with an equine adenovirus.

PMID- 4370150
TI  - Letter: Glioblastoma multiforme.

PMID- 4370152
TI  - Letter: Indomethacin, prostaglandin and hypercalcemia.

PMID- 4370151
TI  - Letter: Immobilization of trypsin on partially oxidized cellulose.

PMID- 4370153
TI  - Letter: Malabsorption in overland travellers to India.

PMID- 4370154
TI  - Letter: Nutrient deficiencies after intensive parenteral alimentation.

PMID- 4370155
TI  - Letter: NAD and chronic schizophrenia.

PMID- 4370156
TI  - Letter: On continuity of care.

PMID- 4370157
TI  - Letter: Other causes of petechiae.

PMID- 4370158
TI  - Letter: Photoinactivation therapy and herpes simplex.

PMID- 4370159
TI  - Letter: The oncogenic potential of dye-light treatment of herpetic lesions.

PMID- 4370160
TI  - Letter: Tinel's sign and Laplace's Law.

PMID- 4370161
TI  - Letter: Viscosity of cellular protoplasm: what do spin probes tell us?

PMID- 4370162
TI  - Letter: Zoster in families.

PMID- 4370163
TI  - Light, electron microscopical, and histochemical study of motor nerve cells in
      spinal cord of hibernating and non-hibernating hedgehog.

PMID- 4370165
TI  - Lipid phase transitions in membrane vesicles from Thermoplasma acidophila.

PMID- 4370164
TI  - Linoleate oxidation products and cardiovascular lesions.

PMID- 4370166
TI  - Lipolysis, aging, and hormones.

PMID- 4370168
TI  - Lipoprotein fractions in maternal, cord and newborn serum.

PMID- 4370167
TI  - Lipolytic effects of sheep beta-lipotropin in rat adipose tissue: interaction
      with theophylline and dihydroergotamine.

PMID- 4370169
TI  - Lipoprotein lipase: comparative properties of the membrane-supported and
      solubilized enzyme species.

PMID- 4370170
TI  - Lipoproteins and lipids in diabetics with and without coronary heart disease.

PMID- 4370171
TI  - Liver disease in transplanted patients.

PMID- 4370172
TI  - Local, reflex, and central commands controlling gill and siphon movements in
      Aplysia.

PMID- 4370173
TI  - Localization of alpha-fetoprotein by immunofluorescence in hyperplastic nodules
      during hepatocarcinogenesis induced by 2-acetylaminofluorene.

PMID- 4370174
TI  - Location of intrahypothalamic estrogen-responsive sites influencing LH secretion
      in the female Rhesus monkey.

PMID- 4370175
TI  - Lumbar myelography and adhesive arachnoiditis.

PMID- 4370176
TI  - Lung cancer: assessment and selective management.

PMID- 4370177
TI  - Luteotrophic factors in the cow: evidence for LH rather than prolactin.

PMID- 4370178
TI  - Magnetic resonance study of spin-labelled rhodopsin.

PMID- 4370179
TI  - Malignant lymphoma with intracytoplasmic IgM crystalline inclusions.

PMID- 4370180
TI  - Malignant mesenchymal tumors of the uterine corpus.

PMID- 4370181
TI  - Malignant tumours following immunosuppression in renal transplantation.

PMID- 4370182
TI  - Mammographic varicosities indicative of a superior mediastinal syndrome. A case
      report.

PMID- 4370183
TI  - Marine sterols. V. Isolation and structure of occelasterol, a new 27-norergostane
      type sterol, from an annelida, Pseudopotamilla occelata.

PMID- 4370185
TI  - Measurement of angiotensin II in an ultrafiltrate of plasma.

PMID- 4370184
TI  - Maternal adrenocorticotrophic hormone and cortisol during labour and vaginal
      delivery.

PMID- 4370186
TI  - Mechanism of adenosine triphosphate-dependent Ca2+ uptake of brain microsomes.

PMID- 4370187
TI  - Mechanisms controlling maternal placental circulation.

PMID- 4370188
TI  - Mechanisms of drug action on recovery processes of cardiac muscle in myocardial
      infarction.

PMID- 4370189
TI  - Mechanisms of hyperlipoproteinemia.

PMID- 4370190
TI  - Mechanisms of insulin action.

PMID- 4370191
TI  - Mechanisms of steroid resistance.

PMID- 4370192
TI  - Mechanisms underlying vasomotor regulation of regional pulmonary blood flow in
      normal and disease states.

PMID- 4370193
TI  - Metabolic regulation of steroidogenesis in isolated adrenal cells of rat. Effect
      of actinomycin D on cGMP-induced steroidogenesis.

PMID- 4370194
TI  - Metabolic regulation of steroidogenesis in isolated adrenal cells of the rat.
      ACTH regulation of cGMP and cAMP levels and steroidogenesis.

PMID- 4370195
TI  - Methionine metabolism in pyridoxine deficiency.

PMID- 4370196
TI  - Microcirculatory effects of prostaglandins E1, E2, and A1 in the rat mesentery
      and cremaster muscle.

PMID- 4370197
TI  - Middle ear masses mimicking glomus tumors: radiographic and otoscopic
      recognition.

PMID- 4370198
TI  - Mitochondrial membranes of inositol-requiring Saccharomyces carlsbergensis:
      covalent binding of a radioactive marker to the outer membrane.

PMID- 4370199
TI  - Mode of action of cholera toxin: stabilization of catecholamine-sensitive
      adenylate cyclase in turkey erythrocytes.
AB  - Preincubating turkey erythrocytes with cholera toxin alters their adenylate
      cyclase (EC 4.6.1.1) system: basal activity, maximal epinephrine-stimulatable
      activity, and affinity of the enzyme reaction for epinephrine are all increased.
      Pretreatment of erythrocytes with choleragenoid prevents these changes. Cholera
      toxin does not alter [(3)H]epinephrine uptake by intact erythrocytes. The
      increase in epinephrine-stimulatable cyclase activity appears to occur at the
      expense of fluoride-stimulatable activity, which is decreased by the toxin. In
      lysates from both toxin-treated and control cells, maximally stimulating amounts
      of epinephrine and fluoride, when added in combination, have a nearly additive
      effect on cyclase activity. These observations suggest that the adenylate cyclase
      system of the turkey erythrocyte may exist in two interconvertible forms, one
      that is catecholamine-responsive but fluoride-insensitive, and another that is
      fluoride-sensitive but not coupled to catecholamine receptors. Cholera toxin
      appears to stabilize the enzyme in its hormone receptor-coupled form.

PMID- 4370200
TI  - Mode of action of chronotropic agents in cardiac Purkinje fibers. Does
      epinephrine act by directly modifying the external surface charge?
AB  - Hauswirth et al. (1968) proposed that epinephrine acts on i(KK2) by adding its
      own positive charge to the external membrane surface near the i(KK2) channel.
      This hypothesis was tested by using noncationic compounds, theophylline and R07
      2956, which mimicked epinephrine's effects on pacemaker activity and on i(KK2).
      In maximally effective doses, theophylline or R07-2956 occluded the effect of
      epinephrine, indicating a shared final common mechanism. Since theophylline and
      R07-2956 are noncationic at pH 7.4, the common mechanism cannot be a direct
      change in external surface charge. On the contrary, epinephrine does not
      interfere with the voltage shift produced by La(+++), which is thought to modify
      the external surface charge. The results argue against the original hypothesis
      but leave open the possibility that an alteration in internal surface charge
      generates the observed voltage shift. The potency of theophylline and R07-2956 as
      phosphodiesterase inhibitors suggests that the final common mechanism begins with
      the elevation of intracellular cyclic AMP, leading to a saturable process which
      limits the voltage shift's magnitude. This hypothesis is used to generate dose
      response curves describing the combined effects of epinephrine and theophylline,
      and these are compared with experimental data.

PMID- 4370201
TI  - Model of molecular mechanism able to generate a depolarization-hyperpolarization
      cycle.

PMID- 4370202
TI  - Modification of neuron properties by electrotonic synapses. I. Input resistance,
      time constant, and integration.

PMID- 4370203
TI  - Modification of neuron properties by electrotonic synapses. II. Burst formation
      by electrotonic synapses.

PMID- 4370204
TI  - Modulation of malate dehydrogenase of young and old rats by various effectors.

PMID- 4370205
TI  - Monovalent cation requirement for ADP inhibition of pyruvate dehydrogenase
      kinase.

PMID- 4370206
TI  - Multicentric reticulohistiocytosis. Fine structural analysis of the synovium and
      synovial fluid cells.

PMID- 4370208
TI  - Multiple glomus tumours.

PMID- 4370207
TI  - Multiple forms of cyclic 3',5'-AMP phosphodiesterase of rat cerebrum and cloned
      astrocytoma and neuroblastoma cells.

PMID- 4370209
TI  - Murine sarcoma virus gene expression: transformants which express viral envelope
      glycoprotein in the absence of the major internal protein and infectious
      particles.
AB  - Expression of the major internal protein and the envelope glycoprotein of murine
      C-type viruses in focus-derived lines of normal rat kidney cells infected with
      Kirsten murine sarcoma virus was measured by radioimmunoassay. Of the clones
      selected, which do not produce virus particles or the major viral structural
      protein, approximately half express the viral envelope glycoprotein at
      concentrations found in productively infected cells. Expression of the envelope
      glycoprotein did not appear to alter significantly the properties of the
      transformed cells in culture.

PMID- 4370210
TI  - Mutagenic action of methyl methane sulphonate on the bluegreen alga Anacystis
      nidulans.

PMID- 4370211
TI  - Mutations affecting adenine phosphoribosyl transferase activity in Chinese
      hamster cells.

PMID- 4370212
TI  - Myoepithelioma of the parotid gland.

PMID- 4370213
TI  - Neoplasms of the kidney, renal pelvis and ureter. A study of 92 primary and 44
      metastic tumours.

PMID- 4370214
TI  - Nephroblastoma with keratinising cysts--(a case report).

PMID- 4370215
TI  - Nephrotic syndrome with oat-cell carcinoma.

PMID- 4370216
TI  - Network analysis as a method for the evaluation of service delivery systems.

PMID- 4370217
TI  - Neural origin of granular cell tumor.

PMID- 4370219
TI  - Neuronal activity before and during eye movements in thalamic internal medullary
      lamina of the cat.

PMID- 4370218
TI  - Neuroblastoma: drug-induced differentiation increases proportion of cytoplasmic
      RNA that contains polyadenylic acid.
AB  - The production of cytoplasmic RNA that contains polyadenylic acid is increased,
      relative to total cytoplasmic RNA, in a neuroblastoma clone, NBE-(A), after
      induction of differentiation by 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone,
      an inhibitor of adenosine 3',5'-monophosphate phosphodiesterase. The amount of
      RNA that contains polyadenylic acid in cytoplasm may be greater in such
      differentiated neuroblastoma cells than in proliferating control cells.

PMID- 4370220
TI  - New approaches to the evaluation and treatment of insomnia. (Preliminary
      results).

PMID- 4370221
TI  - New serotypes of reoviruses isolated from cattle.

PMID- 4370222
TI  - Night terrors.

PMID- 4370223
TI  - Non-productive infection of genetically resistant mouse cells by murine
      cytomegalovirus.

PMID- 4370224
TI  - Non-specific immunostimulation in bronchogenic cancer.

PMID- 4370225
TI  - Nuclear bodies in endothelial cells of human glomeruli.

PMID- 4370226
TI  - Nuclear coupling of 33S and the nature of free radicals in irradiated crystals of
      cystine dihydrochloride.
AB  - The (33)S hyperfine structure has been observed and analyzed in the electron spin
      resonance of gamma-irradiated single crystals of cystine dihydrochloride at 77
      degrees K and at room temperature. The radicals observed at room temperature and
      previously assigned as RCH(2)S are proved to be disulfide radicals, RCH(2)SS.
      However, the RCH(2)S radical is identified by the (33)S measurements in samples
      irradiated at 77 degrees K, annealed at 200 degrees K, and observed at 77 degrees
      K. This monosulfide radical appears to undergo reactions to form disulfide
      radicals at room temperature.

PMID- 4370227
TI  - Nuclear magnetic resonance studies of cancer. V. Appearance and development of a
      tumor systemic effect in serum and tissues.

PMID- 4370228
TI  - Nuclear magnetic resonance titration curves of histidine ring protons. V.
      Comparative study of cytochrome c from three species and the assignment of
      individual proton resonances.

PMID- 4370229
TI  - Nuclear poly (ADPR) and mono (ADPR) residues in tissues with different growth
      rates.

PMID- 4370231
TI  - Nutrient media for plant-parasitic nematodes. VI. Nucleic acids content and
      nucleotide synthesis in Aphelenchoides rutgersi.

PMID- 4370230
TI  - Nucleoside peptides. 6. Synthesis of certain N-(5-amino-1-(beta-D
      ribofuranosyl)imidazole-4-carbonyl)amino acids related to naturally occurring
      intermediates in the purine biosynthetic pathway.

PMID- 4370232
TI  - Observations and comments on two outbreaks of abortion associated with IBR virus
      infection.

PMID- 4370233
TI  - Observations on experimental infection with infectious bovine rhinotracheitis
      virus in rabbits.

PMID- 4370234
TI  - Observations on the first epidemic of foot-and-mouth disease type SAT 1 in
      Tanzania.

PMID- 4370235
TI  - Ocular manifestations of the mucopolysaccharidoses.

PMID- 4370236
TI  - Olivopontocerebellar degeneration. Clinical and ultrastructural abnormalities.

PMID- 4370237
TI  - On the limited peptic digestion of horse heart cytochrome C. isolation of C
      terminal peptide sequences.

PMID- 4370238
TI  - On the luminescence of estrogens.

PMID- 4370239
TI  - On the mechanism of uptake of iron by reticulocytes.

PMID- 4370240
TI  - On the polypeptide composition of an abnormal high density lipoprotein (LP-E)
      occurring in LCAT-deficient plasma.

PMID- 4370242
TI  - Oncogenic activity of an m-dioxane derivatives: 2,6-dimethyl-m-dioxan-4-ol
      acetate (dimethoxane).

PMID- 4370241
TI  - On the relation of products of activated lymphocytes to cell-mediated cytolysis.
AB  - Experiments have been designed to test the hypothesis that soluble mediator
      production and T-cell-mediated cytotoxicity are necessarily related phenomena,
      and that soluble mediators may be involved in the mechanism of cytolysis. To this
      end, agents known to inhibit T-cell-mediated lysis in vitro have been studied for
      their effects on the production of two lymphocyte-derived mediators, lymphotoxin
      (LT) and migration inhibitory factor (MIF). A clear dissociation between mediator
      production and cell-mediated cytolysis was found using inhibitors of protein
      synthesis. Pactamycin and emetine, in doses of 10(-7) M to 10(-6) M, suppressed
      production of MIF and LT with only slight effect on killing of mastocytoma cells
      by immune T cells. On the other hand colchicine and vinblastine inhibited T-cell
      mediated cytolysis in a dose-related manner but had no significant effect on
      either MIF or LT production, A striking dichotomy was also observed after
      augmentation of intracellular cyclic 3'5' adenosine monophosphate (cAMP) levels
      with cholera enterotoxin. Increased cAMP levels were associated with abrogation
      of direct lytic activity, but were without significant effect on MIF or LT
      production in guinea pigs or mice. These findings indicate that mediator
      production and direct lymphocyte-mediated cytolysis can be experimentally
      dissociated and represent independent cell-mediated immune functions.

PMID- 4370243
TI  - Ontogeny of thirst in the rat: effects of hypertonic saline polyethylene glycol,
      and vena cava ligation.

PMID- 4370244
TI  - Oocyte maturation and follicle cell viability in vitro.

PMID- 4370245
TI  - Organizational and attitudinal correlates of citizen board accomplishment in
      mental health and retardation.

PMID- 4370246
TI  - Osteodystrophy of dialysed patients treated with vitamin D.

PMID- 4370247
TI  - Paradoxical sleep in the chick (Gallus domesticus).

PMID- 4370248
TI  - Parathyroid hormone deficiency with Albright's hereditary osteodystrophy.

PMID- 4370249
TI  - Partial purification and characterization of the SV40 T antigen.

PMID- 4370250
TI  - Partial purification and reconstitution of the heme oxygenase system from pig
      spleen microsomes.

PMID- 4370251
TI  - Partial purification of human interferon by affinity chromatography.
AB  - Human interferon prepared by challenge of leukocytes with Sendai virus, or of
      fibroblasts with double-stranded poly(inosinic acid).poly(cytidylic acid), has
      been studied with respect to purification by affinity chromatography. Both
      leukocyte and fibroblast interferons are removed from crude tissue culture fluids
      by means of columns of antibody to leukocyte interferon attached to Sepharose-4B.
      The antibody was prepared in sheep using, as antigen, material that had been
      partially purified by gel filtration through Sephadex G-100 columns. Many of the
      impurities in the crude fibroblast interferon were presumably not recognized by
      the sheep antibodies induced by leukocyte interferon. Fibroblast interferon was,
      therefore, much more effectively purified as the result of this "common
      denominator" approach. The fibroblast product, in contrast to interferon from
      leukocytes, could only be harvested efficiently from the crude starting material
      when a carrier protein (bovine-serum albumin, and later, cytochrome c) was added
      to the eluting buffers to counteract losses, presumably due to adsorption on
      purification and assay equipment. Both varieties of interferon exhibit molecular
      weights of approximately 20,000-25,000, although association with higher
      molecular weight proteins occurs.

PMID- 4370252
TI  - Pathological studies on adenocarcinoma of the uterine cervix in Singapore.

PMID- 4370253
TI  - Percutaneous needle aspiration lung biopsy.

PMID- 4370254
TI  - Peripheral modification of thermoregulatory function during heat acclimation.

PMID- 4370255
TI  - Persistent noncytocidal vesicular stomatitis virus infections mediated by
      defective T particles that suppress virion transcriptase.
AB  - Infectious B virions of vesicular stomatitis virus were 100% lethal to BHK(21)
      (baby hamster kidney) cells when infecting alone, and persistent noncytocidal
      infection could not be achieved with cloned B virions alone. However, a mixture
      of B virions and homologous, short, defective, interfering particles (T
      particles) of a temperature-sensitive mutant of the virus regularly established
      persistently infected, noncytocidal carrier cultures. A long T particle was
      generated during establishment of the carrier culture; we show that this long T
      particle can establish and maintain persistent noncytocidal infection even when
      it infects cells along with virulent wild-type B virions. This long T particle
      causes the production of wild-type B virions with greatly reduced virion
      transcriptase (EC 2.7.7.6; RNA nucleotidyltransferase) levels when coinfecting
      the same cells, so it appears to prevent cytopathology by regulating virus
      transcription. The implications of these findings for rabies and other slowly
      progressing noncytocidal infections are discussed.

PMID- 4370256
TI  - Pharyngoesophageal dysphagia and recurrent laryngeal nerve palsy.

PMID- 4370257
TI  - Phospholipid compositon of mitochondria and microsomes from regenerating rat
      liver and hepatomas of different growth rate.

PMID- 4370258
TI  - Phospholipid metabolism in the eggs and embryos of the sea urchin Arbacia
      punctulata.

PMID- 4370259
TI  - Phosphorylation of acid-soluble proteins in isolated nucleoli of Novikoff
      hepatoma ascites cells. Effects of divalent cations.

PMID- 4370260
TI  - Photophosphorylation not coupled to DCMU-insensitive photosystem II oxygen
      evolution.

PMID- 4370261
TI  - Physical-chemical studies of phospholipids and poly (amino acids) interactions.

PMID- 4370262
TI  - Physiological and biochemical properties of neuromuscular transmission between
      identified motoneurons and gill muscle in Aplysia.

PMID- 4370263
TI  - Physiological properties of developing frog tadpole nerve-muscle junctions during
      repetitive stimulation.

PMID- 4370264
TI  - Plasma adenosine 3',5'-monophosphate in antiinsulin-treated rats.

PMID- 4370265
TI  - Plasma aldosterone during haemodialysis in patients with terminal renal failure.

PMID- 4370266
TI  - Plasminic activity and emotional stress.

PMID- 4370267
TI  - Platelet factor-3 availability and the platelet release reaction.

PMID- 4370268
TI  - Platelets as a source of fibroblast growth-promoting activity.

PMID- 4370269
TI  - Pneumocystis carinii pneumonia.

PMID- 4370270
TI  - Poliomyelitis vaccination in Thailand. I. A pilot study of the administration of
      live poliomyelitis vaccine.

PMID- 4370272
TI  - Polymorphism of adenylate kinase (AK) and adenosine deaminase (ADA) in the Polish
      population.

PMID- 4370271
TI  - Poly(ADP-ribose): release of template restriction in HeLa cells.
AB  - Evidence is presented to show that ADP-ribosylation of nuclear proteins by
      poly(ADP-ribose) polymerase enhances template-primer activity of HeLa cell
      nuclear DNA. We used Escherichia coli DNA polymerase I (EC 2.7.7.7; DNA
      nucleotidyltransferase) as an exogenous probe of nuclear DNA status. Neither NAD
      nor free poly(ADP-ribose) acts directly on the bacterial enzyme. The stimulation
      is specific for formation of ADP-ribosylated proteins and is not a generalized
      polyanion or nucleotide effect on chromatin. The release of template restriction
      is proportional to the capacity of a given cell line to synthesize poly(ADP
      ribose); both the stimulation and poly(ADP-ribose) formation are coordinately
      proportional to NAD concentration. Binding studies with DNA polymerase indicate
      exposure or generation of additional 3'-OH primer sites due to ADP-ribosylation
      in intact nuclei. With intact cells, there appears a correlation among growth,
      physiological template restriction, and the above effects of ADP-ribosylation.

PMID- 4370273
TI  - Polysaccharide synthesis on immobilized phosphorylase.

PMID- 4370275
TI  - Potential antitumor agents. 11. Inhibitors of alkaline phosphatase, an enzyme
      involved in the resistance of neoplastic cells to 6-thiopurines.

PMID- 4370274
TI  - Potential antitumor agents. 10. Synthesis and biochemical properties of 5-N
      alkylamino-,N,N-dialkylamino-, and N-alkylacetamido-1-formylisoquinoline
      thiosemicarbazones.

PMID- 4370276
TI  - Power spectral density of hippocampal theta activity during rhombencephalic
      sleep, after physostigmine administration and during orienting reaction.

PMID- 4370277
TI  - Preparation of microcells by enucleation of micronucleate cells.

PMID- 4370279
TI  - Presence of two active X chromosomes in hybrids between normal human and SV40
      transformed fibroblasts from patients with the Lesch-Nyhan syndrome.

PMID- 4370278
TI  - Presence of repeating sub-sequences and symmetry patterns in proteins.

PMID- 4370280
TI  - Presynaptic inhibition: primary afferent depolarization in crayfish neurons.
AB  - Inhibition of transmission between tactile sensory neurons and interneurons in
      the crayfish was investigated by intracellular recording int the presynaptic
      processes. Inhibition is correlated with a depolarization of the presynaptic
      process, as in the mammalian spinal cord; the depolarization is accompanied by a
      conductance increase, and is mediated by interneurons that can be excited by a
      variety of routes.

PMID- 4370281
TI  - Prevalence of asymptomatic femoral artery atheromas in hyperlipoproteinemic
      patients.

PMID- 4370282
TI  - Prevention and treatment; a stategy for survival.

PMID- 4370283
TI  - Preventive maintenance for mentally ill patients.

PMID- 4370284
TI  - Primary breast and lung carcinoma in the same patient.

PMID- 4370285
TI  - Primary type V hyperlipoproteinaemia (mixed hyperlipaemia): successful response
      to dietary restriction and simfibrate.

PMID- 4370286
TI  - Problem solving: waking and dreaming.

PMID- 4370287
TI  - Proceedings: A possible origin of the 'giant' spontaneous potentials that occur
      after prolonged transmitter release at frog neuromuscular junctions.

PMID- 4370288
TI  - Proceedings: Azurophil and specific granules of blood neutrophils in chronic
      myelogenous leukaemia: and ultrastructural and cytochemical analysis.

PMID- 4370289
TI  - Proceedings: Benign tumours of the kidney in infancy.

PMID- 4370290
TI  - Procollagen: intermediate forms containing several types of peptide chains and
      non-collagen peptide extensions at NH2 and COOH ends.
AB  - A population of procollagen molecules has been isolated from the culture medium
      of a clonal line of calf dermatosparactic cells and shown to have the amino-acid
      composition, physical properties, and molecular structure consistent with
      collagen precursors. Although this procollagen population shares immunologic
      determinants with the procollagen obtained from dermatosparactic skin, it differs
      from the latter in aminoacid composition, in subunit properties, and by its
      content of both amino and carboxyl terminal non-collagen peptide appendages. We
      propose that the cell culture procollagen contains earlier biosynthetic forms of
      dermatosparactic procollagen.

PMID- 4370291
TI  - Progesterone receptors of chick oviduct. Steroid-binding "subunit" formed with
      divalent cations.

PMID- 4370292
TI  - Prolactin release in cattle.

PMID- 4370293
TI  - Propagation of mouse cytomegalovirus in murine renal epithelium.

PMID- 4370294
TI  - Properties of enucleated cells. II. Characteristic overlapping of transformed
      cells is reestablished by enucleates.

PMID- 4370295
TI  - Properties of the specific binding of 125I-nerve growth factor to responsive
      peripheral neurons.

PMID- 4370296
TI  - Prostaglandin inhibition of cyclic-AMP accumulation and rate of lipolysis in fat
      cells.

PMID- 4370297
TI  - Prostaglandin synthesis in rabbit graafian follicles in vitro. Effect of
      luteinizing hormone and cyclic AMP.

PMID- 4370298
TI  - Prostaglandin F production in vitro by granulosa cells from rabbit pre-ovulatory
      follicles.

PMID- 4370299
TI  - Prostaglandin 15-hydroxy dehydrogenase and delta13 reductase levels in the lungs
      of maternal, fetal and neonatal rabbits.

PMID- 4370300
TI  - Protein metabolism in hypertrophied heart muscle.

PMID- 4370301
TI  - Proton equilibria and kinetics in the liver alcohol dehydrogenase reaction
      mechanism.

PMID- 4370302
TI  - Pseudohypoparathyroidism type II: restoration of normal renal responsiveness to
      parathyroid hormone by calcium administration.

PMID- 4370304
TI  - Purification of a ribonuclease inhibitor from Novikoff hepatoma supernatant
      fraction.

PMID- 4370303
TI  - Purification and characterization of anti-A agglutinin from Euhadra callizoma
      amaliae.

PMID- 4370305
TI  - Pyruvate oxidation in neuromuscular diseases. Evidence of a genetic defect in two
      families with the clinical syndrome of Friedreich's ataxia.

PMID- 4370306
TI  - PGF-2 alpha-induced loss of corpus luteum gonadotrophin receptors.

PMID- 4370307
TI  - Quantitative studies of the inhibitory effect of perchlorate on the concentration
      of 36C1O minus 4 125I minus and 99mTcO minus 4 in salivary glands of male and
      female mice.

PMID- 4370308
TI  - Radiation effects and adrenal cortex. VII. Corticosteroid changes in mice
      following whole-body irradiation.

PMID- 4370310
TI  - Rapid estimation of small amounts of formaldehyde liberated during periodate
      oxidation of a sialoglycoprotein.

PMID- 4370309
TI  - Radioimmunoassay of the major group specific protein of endogenous baboon type C
      viruses: relation to the RD-114-CCC group and detection of antigen in normal
      baboon tissues.

PMID- 4370311
TI  - Rapid separation of tumor-promoting agents, phorbol and phorbol myristate acetate
      (12-o-tetradecanoylphorbol-13-acetate) by high-pressure liquid chromatography.

PMID- 4370312
TI  - Rates of disappearance from blood and biological potencies of mammalian
      gonadotropins (HCG and ovine LH) in the toad Bufo bufo bufo (L.).

PMID- 4370313
TI  - Reaction center bacteriochlorophyll triplet states: redox potential dependence
      and kinetics.

PMID- 4370314
TI  - Recent work on virus diseases.

PMID- 4370315
TI  - Receptive fields and response properties of mechanoreceptor neurons innervating
      siphon skin and mantle shelf in Aplysia.

PMID- 4370316
TI  - Recognition of TMV RNA by the tRNA nucleotidyltransferase.

PMID- 4370318
TI  - Recurrent idiopathic polyneuropathy.

PMID- 4370317
TI  - Reconstituted hamster liver microsomal enzyme system for N-hydroxylation of the
      carcinogen 2-acetylaminofluorene.

PMID- 4370319
TI  - Recurrent paroxysmal nonepileptic disorders.

PMID- 4370320
TI  - Red chorda tympani nerve and Bell's palsy.

PMID- 4370321
TI  - Reduced aldosterone secretion during spironolactone treatment in primary
      aldosteronism: report of a case.

PMID- 4370322
TI  - Reduction of ferricytochrome c by hydrogen atoms: evidence for intramolecular
      transfer of reducing equivalent.

PMID- 4370323
TI  - Reduction of serum triglyceride levels by polyunsaturated fat. Studies on the
      mode of action and on very low density lipoprotein composition.

PMID- 4370324
TI  - Regional diversity in excitatory and inhibitory receptive-field organization of
      cat thalamic ventrobasal neurons.

PMID- 4370325
TI  - Regulation of protein phosphorylation and membrane permeability by beta
      adrenergic agents and cyclic adenosine 3':5'-monophosphate in the avian
      erythrocyte.

PMID- 4370326
TI  - Regulation of renal circulation during behavioral changes in the cat.

PMID- 4370327
TI  - Rejection of mammary adenocarcinoma cell tumors and the prevention of progressive
      growth of incipient metastases following intratumor permeation with killed
      Bordetella pertussis.

PMID- 4370328
TI  - Relation between rhythmical hippocampal ("theta") and olfactory (breath) EEG
      activity during spontaneous behaviour and REM sleep in rats.

PMID- 4370329
TI  - Relationship of calcium uptake and calcium-binding protein synthesis in chick and
      rat intestine in response to Solanum malacoxylon.

PMID- 4370330
TI  - Relationship of glucose metabolism to adrenergic transmission in rat mesenteric
      arteries. Effects of glucose deprivation, glucose metabolites, and changes in
      ionic composition on adrenergic mechanisms.

PMID- 4370331
TI  - Release of kallikrein from isolated cellular organelles of the rat submandibular
      salivary gland.

PMID- 4370333
TI  - Renin release by rat kidney slices in vitro: effects of cations and
      catecholamines.

PMID- 4370332
TI  - Renal neoplasms in children.

PMID- 4370334
TI  - Reo-like neonatal calf diarrhoea (NCD) virus demonstrated in Denmark.

PMID- 4370335
TI  - Repetitive patterns of metabolic changes during cortical spreading depression of
      the awake rat.

PMID- 4370337
TI  - Report from Sloan-Kettering Institute. Enzyme therapy and nutritional depletion
      of tumors.

PMID- 4370336
TI  - Replication of arboviruses in mouse organ cultures. I. Results with Middelburg
      virus in organ cultures and peritoneal macrophages.

PMID- 4370338
TI  - Representation of the course of an outbreak of contagious bovine pleuro-pneumonia
      in a sedentary herd of humpless cattle.

PMID- 4370339
TI  - Requirement for double-stranded RNA during the in vitro synthesis of RNA by foot
      and-mouth disease virus replicase.

PMID- 4370340
TI  - Requirement of 3'-terminal poly(adenylic acid) for the infectivity of poliovirus
      RNA.
AB  - Ribonuclease H (EC 3.1.4.34) has been used to remove selectively much of the 3'
      terminal poly(adenylic acid) [poly(A)] from poliovirus RNA by treating the RNA
      with the enzyme in the presence of poly(dT). Over 80% of the poly(A) could be
      removed and the residuum was found as oligo(A) stretches attached to many or all
      of the viral RNA molecules. Reduction of the size of the poly(A) markedly
      decreased the specific infectivity of poliovirus RNA, indicating that poly(A) is
      necessary to the infectivity of the RNA. The virions in plaques deriving from
      infection with treated RNA have a normal amount and size of poly(A), indicating
      that mechanisms exist in infected cells to regenerate normal length poly(A) from
      truncated poly(A).

PMID- 4370341
TI  - Reserve of vasopressin-sensitive adenylate cyclase in toad urinary bladder.

PMID- 4370342
TI  - Residential facilities for hospital-discharged former mental patients. Aspects in
      development.

PMID- 4370343
TI  - Response of chick-embryo kidney cells in vitro to two avian tumor viruses.

PMID- 4370344
TI  - Responses of resistance and capacitance vessels in feline nasal mucosa to
      vasoactive agents.

PMID- 4370345
TI  - Rheumatic manifestations of hypophosphatemia.

PMID- 4370346
TI  - Riboflavin metabolism in cancer.

PMID- 4370347
TI  - Ribonucleotides in newly synthesized DNA of herpes simplex virus.

PMID- 4370348
TI  - Rifamycin derivatives as inhibitors of a ribonucleic acid instructed
      deoxyribonucleic acid polymerase function. Effect of lipophilicity.

PMID- 4370349
TI  - Role of deoxyribonucleic acid-ribonucleic acid hybrids in eukaryotes. Study of
      the template requirements of yeast ribonucleic acid polymerases and nature of the
      ribonucleic acid product.

PMID- 4370350
TI  - Role of enzyme interactions in the regulation of gluconeogenesis. Modification of
      the binding properties of fructose 1,6-diphosphatase by adenosine monophosphate,
      adenosine triphosphate, and fructose 1,6-diphosphate.

PMID- 4370351
TI  - Rotator cuff tear versus suprascapular nerve injury: a problem in differential
      diagnosis.

PMID- 4370352
TI  - Schistosomatium douthitti: effects of thyroxine.

PMID- 4370353
TI  - Screening and genetic counseling programs for sickle cell trait and sickle cell
      anemia.

PMID- 4370354
TI  - Screening tests for renovascular hypertension--an appraisal.

PMID- 4370355
TI  - Secretion rates and chemical composition of oviduct and uterine fluids in sows.

PMID- 4370356
TI  - Selection of hormone-dependent breast cancers.

PMID- 4370357
TI  - Selective inhibition of the synthesis of single-stranded RNA of
      encephalomyocarditis virus by 2-(alpha-hydroxybenzyl)-benzimidazole in cell-free
      systems.

PMID- 4370358
TI  - Selective thymic localization of murine leukemia virus-related antigens in C57BL
      Ka mice after inoculation with radiation virus.
AB  - The tissue distribution and extent of virus-specific antigen expression were
      studied by immunofluorescence as a function of time and of lymphoma development
      in adult C57BL/Ka (Fv-1(b)) mice after intravenous injection of radiation
      leukemia virus, a B-tropic murine leukemia virus. Viral antigens were detected
      earlier in the thymus (1 week) than in the bone marrow, spleen, or lymph nodes (2
      3 weeks). Despite an initial virus-induced thymic involution, the percentage of
      immunofluorescence-positive cells in the thymus rapidly increased thereafter to
      65-80%, at which level it remained until 9 weeks, at which time increases in size
      and weight, histological changes, and an increased number of blastoid cells
      indicated the onset of lymphoma development in the thymus. In contrast, the
      percentage of immunofluorescence-positive cells in the bone marrow, spleen, and
      nodes remained low, and gradually decreased to zero within 8 weeks after
      thymectomy. The selective thymic localization of antigens induced by radiation
      leukemia virus in C57BL/Ka mice is in striking contrast to the previously
      reported ubiquitous tissue distribution of the Gross-AKR virus, an N-tropic
      virus, in its natural host, the Fv-1(n), AKR strain with a high incidence of
      leukemia.

PMID- 4370359
TI  - Sensation and sensibility in the upper extremity.

PMID- 4370360
TI  - Sensitivity of target cells to the cytotoxic effects of lymphocytes induced by
      interferon.

PMID- 4370361
TI  - Sensory transmission through lemniscal pathway during voluntary movement in the
      cat.

PMID- 4370362
TI  - Separation of amino acids from untreated urine on thin layers of silica gel.

PMID- 4370364
TI  - Septal hyperdipsia: specific enhancement of drinking to angiotensin in rats.

PMID- 4370363
TI  - Separation of newly synthesized nucleohistone by equilibrium centrifugation in
      cesium chloride.

PMID- 4370365
TI  - Serological examination of a sample of human population and some animal species
      for the presence of antibodies to Yaba 1 virus.

PMID- 4370366
TI  - Serum and tissue lipid metabolism and effect of nicotinic acid in different types
      of hyperlipidemia.

PMID- 4370368
TI  - Serum lipoproteins and coronary heart disease.

PMID- 4370367
TI  - Serum lipoprotein abnormalities in patients with ischaemic heart disease:
      comparisons with a control population.
AB  - The frequency and nature of abnormalities of serum lipoproteins have been
      studied, using quantitative techniques, in 143 patients with ischaemic heart
      disease (I.H.D.). Rigorous selection criteria were used. The findings were
      related to the distribution of lipoprotein concentrations in a carefully screened
      control population. Hyperlipoproteinaemia occurred in 55% of patients and in 11
      out of 15 patients aged less than 40 years. Raised triglyceride and cholesterol
      concentrations in very low density lipoprotein were the most frequent
      abnormalities followed by raised cholesterol content of low density lipoprotein.
      In young patients high density lipoprotein levels were subnormal.
      Hyperlipoproteinaemia of W.H.O. types IIa, IIb, III, IV, and V all seemed to be
      over-represented in I.H.D. I.H.D. patients with type IIa, IIb, and IV
      abnormalities were all significantly younger than I.H.D. patients with normal
      lipoprotein levels.

PMID- 4370369
TI  - Short length amino acid sequence homology among ancestrally unrelated proteins.

PMID- 4370370
TI  - Sialyl transferase activities of rat ascites hepatoma cells and rat liver.

PMID- 4370371
TI  - Similar effects of calitonin, insulin and somatomedin A on lipolysis and uptake
      of calcium and glucose in rat adipose tissue in vitro.

PMID- 4370372
TI  - Simultaneous evaluation of the pituitary reserve of GH, TSH, ACTH and LH in
      children.

PMID- 4370373
TI  - Simultaneous stimulation test for the anterior pituitary hormones.

PMID- 4370374
TI  - Skeletal maturation of the hand and wrist of young children in Baghdad.

PMID- 4370375
TI  - Sleep of depressed patients in remission.

PMID- 4370376
TI  - Sleep-associated growth hormone (GH) release in schizophrenia.

PMID- 4370377
TI  - Slow evolution of transferrin and albumin in birds according to micro-complement
      fixation analysis.

PMID- 4370378
TI  - Society pays for the learning disabled.

PMID- 4370379
TI  - Solvent isotope effects on the structure and function of mitochondrial membranes
      in aqueous media.

PMID- 4370380
TI  - Some chemical and stereochemical modifications of the erythromycin lactone rings.

PMID- 4370381
TI  - Some in vivo interactions of oestradiol with the mouse vagina.

PMID- 4370382
TI  - Some peculiarities of metabolism of the myocardium under conditions of
      experimental disturbance of the microcirculation.

PMID- 4370383
TI  - Some recent advances in virilizing and feminizing syndromes and hirsutism.

PMID- 4370384
TI  - Specific binding of 8-anilinonaphthalene sulfonate to diphosphopyridine
      nucleotide-linked isocitrate dehydrogenase from bovine heart.

PMID- 4370385
TI  - Specificity of ribonucleic acid chain initiation by bacteriophage T3-induced
      ribonucleic acid polymerase.

PMID- 4370386
TI  - Spectral characterization of 15N spin labels.

PMID- 4370387
TI  - Spinal and supraspinal factors in the control of voluntary activity under normal
      and pathological conditions.

PMID- 4370388
TI  - Statistical quality control and routine data processing for radioimmunoassays and
      immunoradiometric assays.

PMID- 4370389
TI  - Stereotactic Curie-therapy of pituitary adenomas. A long-term follow-up study.

PMID- 4370390
TI  - Steroid hormones and breast cancer.

PMID- 4370391
TI  - Stimulated formation of cyclic adenosine 3':5'-monophosphate by aspartate and
      glutamate in cerebral cortical slices of guinea pig.

PMID- 4370392
TI  - Stimulation of the synthesis of very low density lipoproteins in rooster liver by
      estradiol.

PMID- 4370393
TI  - Stimulation of vascular smooth muscle sodium, potassium--adenosinetriphosphatase
      by vasodilators.

PMID- 4370394
TI  - Stochastic models for single neuron firing trains: a survey.

PMID- 4370395
TI  - Stress and the hormonal regulation of the immune response in mice.

PMID- 4370397
TI  - Structural investigation of oxalate-soluble rapeseed (Brassica campestris)
      polysaccharides. 3. An arabinan.

PMID- 4370396
TI  - Stress, insulin antagonist and transient diabetes mellitus in the rat.

PMID- 4370398
TI  - Structure of yeast hexokinase. 3. Low resolution structure of a second crystal
      form showing a different quaternary structure, heterologous interaction of
      subunits and substrate binding.

PMID- 4370399
TI  - Studies on an extracellular coat of mammalian sperm with reference to its DNA
      content.

PMID- 4370400
TI  - Studies on feline lymphosarcoma in the Sydney area.

PMID- 4370401
TI  - Studies on lipid and fatty acid composition of human hepatoma tissue.

PMID- 4370402
TI  - Studies on the angiotensin II receptor in the zona glomerulosa of the rat adrenal
      gland.

PMID- 4370403
TI  - Studies on the conformational changes of metalloproteins induced by electrons in
      water-ethylene glycol solutions at low temperatures. Cytochrome C.

PMID- 4370404
TI  - Studies on the differential response to glucagon concentration on gluconeogenesis
      in isolated hepatocytes containing high and low glycogen.

PMID- 4370405
TI  - Studies on the mechanism of action of udp-D-glucose dehydrogenase from beef
      liver. II.

PMID- 4370406
TI  - Studies on the metabolism of ATP by isolated bacterial membranes: role of
      succinyl CoA synthetase in diglyceride kinase activity.

PMID- 4370407
TI  - Studies on vitamin D and its analogs. I. Synthesis of 1alpha-hydroxycholest-5
      ene.

PMID- 4370408
TI  - Study of enterovirus replication in human tissue explants, using photosensitized
      virus strains.

PMID- 4370409
TI  - Study of the oxygen effect mediated by Janus green B.

PMID- 4370410
TI  - Subcellular distribution of oxidative enzymes in human, inflamed and dilantin
      hyperplastic gingiva.

PMID- 4370411
TI  - Subcellular localization of ribonucleotide reductase in Novikoff hepatoma and
      regenerating rat liver.

PMID- 4370412
TI  - Subclinical congenital cytomegalovirus infection and hearing impairment.

PMID- 4370413
TI  - Subcutaneous adipose tissue and lipids in blood in growth hormone deficiency
      before and after treatment with human growth hormone.

PMID- 4370414
TI  - Substrate activation and product inhibition of LDH activity in human skeletal
      muscle.

PMID- 4370415
TI  - Succinate dehydrogenase and cytochrome oxidase in adult and plerocercoid
      Diphyllobothrium latum.

PMID- 4370416
TI  - Suppression of fibrinolysin T activity fails to restore density-dependent growth
      inhibition to SV3T3 cells.

PMID- 4370417
TI  - Surgery of the pterygoid fossa.

PMID- 4370418
TI  - Survival and growth in a woman with untreated hypothalamic panhypopituitarism of
      21 years' duration.
AB  - A 29-year-old woman with evidence of a craniopharyngioma and documented
      panhypopituitarism is described. Clinical and laboratory evaluation revealed
      deficiencies of follicle-stimulating hormone, luteinizing hormone, thyroid
      stimulating hormone, growth hormone, prolactin, adrenocorticotropic hormone and
      antidiuretic hormone. Prompt release of several pituitary hormones was noticed
      after administration of the hypothalamic releasing hormones FSH/LH-RF and
      thyrotropin-releasing hormone, whereas insulin-induced hypoglycemia, levodopa,
      chlorpromazine and clomiphene citrate, all of which act at the level of the
      hypothalamus, did not alter basal pituitary secretion. The patient's height of 60
      inches, despite panhypopituitarism, and the interpretation of the above data are
      discussed in the light of current concepts regarding the dynamics of the
      hypothalamic-hypophyseal system.

PMID- 4370419
TI  - Sympathetic-parasympathetic interactions on the ventricular myocardium: possible
      role of cyclic nucleotides.

PMID- 4370420
TI  - Synthesis and antimicrobial activity of aliphatic nitro compounds.

PMID- 4370421
TI  - Synthesis and antiprotozoal activity of 1-(3-chloro-2-hydroxypropyl)-substituted
      nitroimidazoles.

PMID- 4370422
TI  - Synthesis and biological activity of 3-deoxy-1alpha-hydroxyvitamin D3.

PMID- 4370423
TI  - Synthesis and secretion of plasma lipoproteins.

PMID- 4370424
TI  - Synthesis of diphosphoinositide by a soluble fraction of Saccharomyces
      cerevisiae.

PMID- 4370425
TI  - Synthesis of viral mRNA and polyadenylate by a ribonucleoprotein complex from
      extracts of VSV-infected cells.

PMID- 4370426
TI  - Synthesis of 1-(3-deoxy-beta-D-psicofuranosyl)uracil and related compounds.
AB  - D-Fructose affords on treatment with cyanamide 2-amino-beta-D
      fructofuro[2',3':3,4]-oxazoline which is not isolated but transformed directly by
      the reaction with ethyl propiolate into O(2,3)-anhydro-2-[beta-D
      fructofuranosyl]uracil. This compound is benzoylated to the 1',4',6'-tri-O
      benzoyl derivative by the action of benzoyl cyanide and triethylamine. On
      treatment with hydrogen chloride/dimethylformamide, the latter intermediate is
      converted to the 1-[1,4,6-tri-O-benzoyl-3-chloro-3-deoxy-beta-D
      psicofuranosyl]uracil 1',4',5'-tribenzoate from which the title nucleoside
      derivative is obtained by methanolysis.

PMID- 4370427
TI  - Temperature effects on the concanavalin A molecule and on concanavalin A binding.

PMID- 4370428
TI  - Test and teach number two.

PMID- 4370430
TI  - The absorption of conjugated oestrogen and sodium oestrone sulphate from the
      vagina.

PMID- 4370429
TI  - Testing of antiviral compounds against Mengo virus infection of mice. I.
      Screening of compounds and statistical evaluation of their effects.

PMID- 4370431
TI  - The action of phospholipase C and lipase on black film bilayer membranes.

PMID- 4370432
TI  - The adhesion of BHK and PyBHK cells to the substratum.

PMID- 4370435
TI  - The archaic barbiturate hypnotics.

PMID- 4370434
TI  - The apolipoproteins.

PMID- 4370436
TI  - The binding of reduced nicotinamide adenine dinucleotide-cytochrome b5 reductase
      to hepatic microsomes.

PMID- 4370437
TI  - The carbohydrate moiety of sea cucumber (Thyone briareus) gelatin.

PMID- 4370438
TI  - The changing attitudes of women: implications for psychotherapy.

PMID- 4370439
TI  - The clinical and chemical heterogeneity of the beta-thalassemias.

PMID- 4370440
TI  - The clinical-chemical application of the NADH test for the determination of
      diamine oxidase activity in human pregnancy.

PMID- 4370442
TI  - The denervated heart. A model for studying autonomic control of the heart.

PMID- 4370441
TI  - The degradation of ribonucleic acids injected into Xenopus laevis oocytes.

PMID- 4370443
TI  - The detection of hyaluronidase on electrophoresis membranes.

PMID- 4370444
TI  - The development of nerve-muscle junctions in Rana catesbeiana tadpoles.

PMID- 4370445
TI  - The effect of alpha-tocopherol on cerium induced changes in drug and lipid
      metabolism of rat.

PMID- 4370446
TI  - The effect of cyclic 3',5'-adenosine monophosphate on yeast glyceraldehyde-3
      phosphate dehydrogenase. II. Initial velocity kinetic studies.

PMID- 4370447
TI  - The effect of glucagon on adenosine 3',5'-monophosphate (cyclic AMP), glucose,
      insulin and growth hormone in the full term newborn and children.

PMID- 4370448
TI  - The effect of orally administered cocaine on sleep of depressed patients.

PMID- 4370449
TI  - The effect of population density on phenylalanine hydroxylase activity in rat
      hepatoma cells in culture.

PMID- 4370450
TI  - The effect of prior inoculation with an enterovirus (LEV 4) on rhinovirus
      infection of volunteers.

PMID- 4370451
TI  - The effect of pH on hycanthone methanesulfonate-induced inactivation and mitotic
      recombination in saccharomyces.

PMID- 4370452
TI  - The effect of synthetic corticotropin analogues on adrenocortical, anterior
      pituitary and testicular function.

PMID- 4370453
TI  - The effect of Ro 20-1724 upon induced beta-galactosidase synthesis in Escherichia
      coli.

PMID- 4370454
TI  - The effect of 1-sarcosine, 8-leucyl angiotensin II on the pressor effect of
      infused angiotensin II.

PMID- 4370455
TI  - The effects of diet cholesterol on the synthesis of rat serum apolipoproteins.

PMID- 4370456
TI  - The effects of nicotinamide on mouse sleep.

PMID- 4370457
TI  - The effects of some anti-inflammatory drugs on the acute-phase proteins in
      rheumatoid arthritis.

PMID- 4370458
TI  - The effects of Lioresal on synaptic activity in the isolated spinal cord.

PMID- 4370459
TI  - The effects of PGE1 on the spontaneous motility of the guinea pig and rat female
      reproductive tracts, in vitro.

PMID- 4370460
TI  - The establishment of a line of visna virus-producing human astrocytes (V-1181N1).

PMID- 4370461
TI  - The evolution of ovarian steroid hormones during luteolysis and folliculogenesis
      in the cow.

PMID- 4370463
TI  - The experimental pathology of cycad toxicity with special reference to oncogenic
      effects.

PMID- 4370464
TI  - The face in sacred art of the Upper Sepik River of New Guinea: analogies to neuro
      developmental aspects and to prosopagnosia. 3. Neuropathologic aspects:
      prosopagnosia.

PMID- 4370465
TI  - The formation of arabino nucleosides from 3-acetamido-1,2-di-O-acetyl-3,5-dideoxy
      d-ribofuranose during the fusion synthesis.

PMID- 4370466
TI  - The fructose 1,6-diphosphatase-phosphofructokinase substrate cycle. A site of
      regulation of hepatic gluconeogenesis by glucagon.

PMID- 4370467
TI  - The furocoumarin photosensitizing effect on the virus-producing Graffi leukaemia
      cells.

PMID- 4370468
TI  - The glomerular basement membrane in long-term allografts with heavy proteinuria.

PMID- 4370469
TI  - The hemicellulose of pollen grains of Phoenix dactylifera.

PMID- 4370470
TI  - The immune response to virally determined tumor associated antigens.

PMID- 4370471
TI  - The importance of DNA size for successful transfection of chicken embryo
      fibroblasts.

PMID- 4370473
TI  - The influence of a conscious wish on dreams: a methodological study of dream
      meaning and function.

PMID- 4370474
TI  - The influence of cholesterol on molecular motion in egg lecithin bilayers--a
      variable-frequency electron spin resonance study of a cholestane spin probe.

PMID- 4370472
TI  - The in vitro synthesis of avian myeloblastosis viral RNA sequences.
AB  - Isolated nuclei, prepared from myeloblasts of chicks infected with avian
      myeloblastosis virus, synthesize RNA sequences present in avian myeloblastosis
      viral RNA. These sequences are also formed during transcription of chromatin,
      isolated from myeloblasts, by DNA-dependent RNA polymerases purified from
      Escherichia coli or calfthymus. In the latter case, transcription is alpha
      amanitin sensitive. Formation of hybrids between RNA and avian myeloblastosis
      virus DNA probes has been monitored by the combined use of ribonucleases A, T(1),
      and H, and ribonucleases specific for single strands.

PMID- 4370475
TI  - The influence of supraoptimal temperature on poliovirus type 1 Mahoney strain
      reproduction.

PMID- 4370476
TI  - The influence of the size of wuartz dust particles on the reaction of lung
      tissue.

PMID- 4370478
TI  - The interaction of cyclic 3',5'-adenosine monophosphate with yeast glyceraldehyde
      3-phosphate dehydrogenase. I. Equilibrium dialysis studies.

PMID- 4370477
TI  - The influence of the vegetative nerve system on the maximal conduction velocity
      in the atrioventricular bundle and in the cardiac ventricles measured by the
      differential quotient of QRS. Investigations in dogs.

PMID- 4370479
TI  - The involvement of human placental microsomal cytochrome P-450 in aromatization.

PMID- 4370480
TI  - The isolation and properties of a rabbit liver binding protein specific for
      asialoglycoproteins.

PMID- 4370481
TI  - The isolation of chemically pure elastins in a form suitable for mechanical
      testing.

PMID- 4370482
TI  - The isolation of soluble proteins, glycoproteins, and proteoglycans from bone.

PMID- 4370483
TI  - The isolation of terminally cross-linked DNA and kinetics of venom
      phosphodiesterase.

PMID- 4370484
TI  - The mechanism of water-proton relaxation in enzyme paramagnetic-ion complexes. 1.
      The Gd(3)-lysozyme complex.

PMID- 4370485
TI  - The metabolism of 25-hydroxycholecalciferol by isolated renal tubules in vitro as
      studied by a new chromatographic technique.

PMID- 4370487
TI  - The nucleases from Acrocylindrium sp. IV. Purification and properties of
      exonuclease.

PMID- 4370486
TI  - The modulating effect of cholera enterotoxin on the immune response.

PMID- 4370488
TI  - The phosphorylation and subsequent metabolism of 1-aminopropan-2-ol.

PMID- 4370490
TI  - The polypeptide compositions of bovine cytochrome oxidase and its "proteinase
      treated" derivative.

PMID- 4370489
TI  - The polyoma pseudovirion--its properties, production, and use in transferring DNA
      to mouse and human cells.

PMID- 4370491
TI  - The preparation of 1-deoxy-1-halogeno-D-fructoses.

PMID- 4370492
TI  - The properties and origin of the proteins in the SV40 nucleoprotein complex.

PMID- 4370493
TI  - The protective effects of nucleotides on the histamine hypersensitivity of
      Bordetella pertussis-treated mice.

PMID- 4370494
TI  - The purification of glycerate kinase from Hyphomicrobium sp. and Pseudomonas AM1:
      product identification.

PMID- 4370495
TI  - The redox properties of the cytochromes of purified complex 3.

PMID- 4370496
TI  - The regulation of polyamine synthesis during the stringent control in Escherichia
      coli.

PMID- 4370497
TI  - The renin-angiotensin system and aldosterone secretion during sodium depletion in
      the rat.

PMID- 4370499
TI  - The role of cyclic 3'5'-AMP and its derivatives in lipid and carbohydrate
      metabolism.

PMID- 4370498
TI  - The role of calcium in insulin action. I. Purification and properties of enzymes
      regulating lipolysis in human adipose tissue: effects of cyclic-AMP and calcium
      ions.

PMID- 4370500
TI  - The role of the amino group in subunit association and receptor site interaction
      for ovine luteinizing hormone as studied by acylation.

PMID- 4370501
TI  - The role of the secretory immune system in protection against agents which infect
      the respiratory tract.

PMID- 4370502
TI  - The state of water on hydrated collagen as studied by pulsed NMR.

PMID- 4370503
TI  - The susceptibility of the fetus and child to chemical pollutants. Viral etiology
      of cancer: two hypotheses with relevance to chemical exposures.

PMID- 4370504
TI  - The synthesis and biological activity of peptides corresponding to the first
      nineteen amino acids of adrenocorticotropin containing delta-aminovaleric and
      omega-aminocaprylic acids.

PMID- 4370505
TI  - The synthesis of virus-specific polypeptides on polyribosomes isolated from the
      cells infected with encephalomyocarditis virus.

PMID- 4370506
TI  - The toxic optic neuropathies.

PMID- 4370507
TI  - The ultrastructure of erythropoiesis in two haemoglobinopathies.

PMID- 4370508
TI  - The use of conjugated oestrogen in oral contraception.

PMID- 4370509
TI  - The use of lymphangiography in melanoma.

PMID- 4370511
TI  - Theoretical analysis of the oxidation of amylose by periodate ion as an example
      of cooperative effects in polymer kinetics.

PMID- 4370510
TI  - The value of resection in tumors involving the chest wall.

PMID- 4370512
TI  - Threshold of the early components of the averaged electroencephalic response
      determined with tone pips and clicks during drug-induced sleep.

PMID- 4370513
TI  - Thyrotropin-induced aggregation-promoting factors of adult cultured thyroid
      cells.

PMID- 4370514
TI  - Tissue cytochrome oxidase activity and copper, iron, and pantothenic acid
      nutrition in the growing rat.

PMID- 4370515
TI  - Traffic of metabolites between blood and tissue.

PMID- 4370516
TI  - Transformation of hamster embryo and human embryo cells by temperature sensitive
      mutants of herpes simplex virus type 2.

PMID- 4370517
TI  - Transformation-defective virus mutants in a class of morphologic revertants of
      sarcoma virus transformed nonproducer cells.

PMID- 4370518
TI  - Transfusion-acquired cytomegalovirus infection in newborn infants.

PMID- 4370519
TI  - Transient effect of angiotensin II infusion into the lateral ventricle of the
      brain on the blood ADH level in dogs.

PMID- 4370521
TI  - Transplantation of nervous system tumors in diffusion chambers.

PMID- 4370520
TI  - Translation in vitro of total nuclear RNA from HeLa cell nuclei infected with
      adenovirus 2.
AB  - Total heterogeneous nuclear RNA from HeLa cells infected with adenovirus for 18
      20 hr stimulates amino acid incorporation into protein in a cell-free system from
      Ehrlich ascites tumors. This stimulation of protein synthesis by the nuclear RNA
      requires intact nuclei. The role of nuclei in this system is unknown, but
      evidence is presented that the nuclei are involved in the conversion of high
      molecular-weight RNA to low-molecular-weight species. Some of the newly
      synthesized polypeptides appear to resemble the virion polypeptides.

PMID- 4370523
TI  - Transport of ACTH across human placenta.

PMID- 4370522
TI  - Transport of lipids in insects.
AB  - Many insect species are almost completely dependent on lipids for their metabolic
      needs, although this is usually a function of developmental stage. The primary
      storage organ is the fat body, which can constitute 50% of the fresh weight of
      the insect and also acts as the major metabolic center (analogous to the
      vertebrate adipose tissue and liver). Bathing the fat body (and all other tissues
      and organs) is the hemolymph, the main functions of which are to transport
      nutrient substrates to utilization sites and to deliver metabolic wastes to the
      excretory system. Although neutral lipids are stored as triglycerides, in times
      of need they appear to be endergonically released into the hemolymph as
      diglycerides in the majority of insects thus far studied (particularly silkmoths
      and locusts). Indeed, diglycerides constitute the largest neutral lipid fraction
      in the hemolymph of silkmoths, locusts, cockroaches, bugs, etc. In the hemolymph
      the diglyceride is found as a constituent of specific lipoproteins, and one
      specific lipoprotein class (lipoprotein I; high density lipoprotein) appears to
      be necessary for the transport of diglyceride from the fat body cell into the
      hemolymph. This particular lipoprotein is also involved in the transport of
      cholesterol from the gut into the hemolymph. Thus, lipoprotein I appears to be
      the major neutral lipid and sterol transport agent in the insects studied and, in
      addition, plays a regulatory role in the release of both diglycerides and
      sterols. Hemolymph lipoprotein II (very high density lipoprotein) may be
      important in providing protein and lipid to the insect ovary during oogenesis.
      Ecdysone, the polyhydroxy steroidal insect molting hormone, is probably carried
      "free" in the hemolymph, although reports exist of specific hemolymph-binding
      proteins in some species. The other major insect growth hormone, juvenile
      hormone, is transported by hemolymph lipoproteins in silkmoths and locusts and by
      a lower molecular weight hemolymph protein in the tobacco hornworm.

PMID- 4370524
TI  - Traumatic induction of an intraoral reinfection with herpes simplex virus. Report
      of a case.

PMID- 4370525
TI  - Treatment of acute cholecystitis by routine urgent operation.

PMID- 4370526
TI  - Trophoblastic disease diagnosis and management.

PMID- 4370527
TI  - Tumor viruses at Cold Spring Harbor.

PMID- 4370528
TI  - Turnover of phosphatidylglycerol in Streptococcus sanguis.

PMID- 4370529
TI  - Two cases of pseudo-gout.

PMID- 4370530
TI  - Two forms of mouse interferon messenger RNA.

PMID- 4370531
TI  - Two routes for synthesis of phosphoenolpyruvate from C4-dicarboxylic acids in
      Escherichia coli.

PMID- 4370532
TI  - Ultrastructural changes in the smooth musculature of antrum and pylorus in
      presence of ulcus ventriculi.

PMID- 4370534
TI  - Ultrastructural studies of early nidation in pregnancy and pseudopregnancy.

PMID- 4370535
TI  - Ultrastructure of the inclusion bodies and nuclear abnormalities in beta
      thalassemic erythroblasts.

PMID- 4370533
TI  - Ultrastructural evidence for leakage of lysosomal contents after phagocytosis of
      monosodium urate crystals. A mechanism of gouty inflammation.
AB  - To obtain direct evidence for the mechanism involved in gouty inflammation, human
      leukocytes were incubated with synthetic monosodium urate microcrystals. To trace
      the phago(lyso)somal contents, colloidal carbon, ferritin, Thorotrast(R) or
      horseradish peroxidase was added to the incubation medium, or acid phosphatase
      activity was localized cytochemically. The interaction was analyzed in time
      sequence by electron microscopy. By 5 minutes' incubation, urate crystals and
      tracers had appeared in the single membrane-bounded vacuoles of leukocytes. After
      30 minutes' incubation, the vacuoles containing the urate crystals and the
      tracers were found in more than 50% of the leukocyte population. The
      phago(lyso)somal membrane was occasionally discontinuous, and the tracers were
      found in the free cytoplasm near the membrane opening as well. After 60 minutes'
      or more incubation, the phago(lyso)somal changes and the cytoplasmic localization
      of the tracers were common, and many cells showed signs of degeneration. Urate
      crystals mixed in cell debris were often found to be ingested by other
      leukocytes. These results have been interpreted as follows. Monosodium urate
      crystals are avidly phagocytized. The urate crystal-containing phagosomes
      eventually become phagolysosomes. The phagolysosomal membrane is damaged and the
      contents leak out into the cytoplasm. The leakage of the hydrolases initiates the
      host cell injury. The urate crystals released by cell disruption are again
      phagocytized by other cells and the series of events are repeated.

PMID- 4370536
TI  - Ultrastructure of tumors induced in mice by Moloney and Harvey strains of murine
      sarcoma virus.

PMID- 4370537
TI  - Unit responses in the hypothalamus.

PMID- 4370538
TI  - Unstable hemoglobins and thalassemia: some properties of Hb Koln.

PMID- 4370539
TI  - Uptake of 2-deoxyglucose by BALB-3T3 cells: changes after polyoma infection.

PMID- 4370540
TI  - Ureteral and vesical metastases in nephroblastoma.

PMID- 4370541
TI  - Use of stochastic signals in evaluation of the dynamic properties of a neuronal
      system.

PMID- 4370542
TI  - Use of unithiol for reducing radiation hazard of renal scintigraphy with
      chlormerodrin 203Hg. I. Estimation of the urinary excretion of 203Hg.

PMID- 4370543
TI  - Use of unithiol for reducing radiation hazard of renal scintigraphy with
      chlormerodrin 203Hg. II. Scintigraphic estimation.

PMID- 4370544
TI  - Value structure as a predictor of type of discharge among residential addicts.

PMID- 4370545
TI  - Variable sensitivity of different hypertensives to constant infusion of
      angiotensin.

PMID- 4370546
TI  - Variables related to success in a medical rehabilitation setting.

PMID- 4370547
TI  - Varicella dendritic keratitis.

PMID- 4370548
TI  - Various aspects of alpha-thalassemia.

PMID- 4370549
TI  - Vastus lateralis cytochrome oxidase activity and its relationship to maximal
      oxygen consumption in man.

PMID- 4370550
TI  - Very early effects of aminonucleoside on some rat liver enzymes.

PMID- 4370551
TI  - Vesicular stomatitis virus envelope glycoprotein alterations induced by host cell
      transformation.

PMID- 4370552
TI  - Virilization in pregnancy associated with polycystic ovary disease.

PMID- 4370553
TI  - Virogenic nontransformed cells isolated following infection of normal rat kidney
      cells with B77 strain Rous sarcoma virus.

PMID- 4370554
TI  - Virus antibody in synovial fluid of rheumatoid and control patients.

PMID- 4370556
TI  - Vitamin D physiology and its importance in dairy cattle: a review.

PMID- 4370555
TI  - Visual loss: a rare complication following oil myelography. Case report and
      review of the literature.

PMID- 4370557
TI  - Vitamin D: mode of action and biomedical applications.

PMID- 4370558
TI  - Waxes of the uropygial gland secretion of birds of the genus Parus.

PMID- 4370559
TI  - Workshop on possible pharmacologic mechanisms for enhancement of lung maturation.

PMID- 4370560
TI  - 1Alpha-hydroxyvitamin D3. An analog of vitamin D which apparently acts by
      metabolism to 1alpha, 25-dihydroxyvitamin D3.

PMID- 4370561
TI  - 14CO2 fixation and glycolate metabolism in the dark in isolated maize (Zea mays
      L.) bundle sheath strands.

PMID- 4370562
TI  - 3-Epi-20-hydroxyecdysone from meconium of the tobacco hornworm.

PMID- 4370563
TI  - 8-(6-Aminohexyl)-amino-adenine nucleotide derivatives for affinity
      chromatography.

PMID- 4370564
TI  - What do women want?

PMID- 4370565
TI  - [Amyloidosis of the peripheral nervous system and its clinical manifestation].

PMID- 4370566
TI  - [The anticoagulation incident in neurology].

PMID- 4370567
TI  - Some applications of calorimetry in biochemistry and biology.

PMID- 4370568
TI  - [Age characteristics of the effect of cyclic 3',5'-AMP on tissue lipolytic
      activity].

PMID- 4370569
TI  - U.S. childhood cancer deaths by cell type, 1960-68.

PMID- 4370570
TI  - What cyclic AMP is all about.

PMID- 4370571
TI  - High density lipoproteins in cholestasis.

PMID- 4370572
TI  - [The determination of tube kV and inherent filtration in x-ray departments
      (author's transl)].

PMID- 4370573
TI  - [The diagnositic value of direct vision biopsies in stomach tumors].

PMID- 4370574
TI  - [The differential diagnosis of cysts in the posterior cranial fossa (author's
      transl)].

PMID- 4370575
TI  - Some diseases of zoo animals.

PMID- 4370576
TI  - [Our experience with pancreatic sonography (author's transl)].

PMID- 4370577
TI  - On a family with coexistence of phenotypes II and III hyperlipoproteinemia.

PMID- 4370578
TI  - Some hematologic and biochemical observations in the mongoose (Herpestes
      auropunctatus).

PMID- 4370580
TI  - Cell inoculum size and rate of subsequent exponential multiplication in human
      cell lines.

PMID- 4370579
TI  - [The influence of ellagic acid on the oncolytic effect of clostridium M55
      (author's transl)].

PMID- 4370581
TI  - [The jejunum as a stomach substitute. Histological and enzyme-histochemical
      findings in iso- and anisoperistaltic implanted sections].

PMID- 4370582
TI  - [The kinetics of the gall bladder due to congenital anomalies (author's transl)].

PMID- 4370583
TI  - [The liver and rifampicin].

PMID- 4370584
TI  - [Use of a medical information system for differential diagnosis of several
      infectious and infectious-allergic diseases of the central nervous system].

PMID- 4370585
TI  - [Use of aminoglutethimide in the treatment of Cushing's syndrome].

PMID- 4370586
TI  - [Age of closure of the epiphyses of the knee in the school population of the City
      of Buenos Aires].

PMID- 4370587
TI  - Role of cyclic nucleotides in the nervous system.

PMID- 4370588
TI  - Role of cytochrome b5 in hydroxylation by a reconstituted cytochrome P-450
      containing system.

PMID- 4370590
TI  - Loss of mitotic response of the thyroid gland to TSH in hypophysectomized rats
      and its partial restoration by anterior and posterior pituitary hormones.

PMID- 4370589
TI  - Role of lipid in the formation and function of the respiratory system of
      Staphylococcus aureus.

PMID- 4370592
TI  - Role of splenic arteriography in evaluation of malignant tumors in the body of
      the pancreas.

PMID- 4370591
TI  - Role of phospholipids in transport and enzymic reactions.

PMID- 4370593
TI  - Role of the amygdaloid complexes in the stress-induced release of ACTH in the
      rat.

PMID- 4370594
TI  - Role of 3-mercaptopyruvate sulfurtransferase in the formation of the iron-sulfur
      chromophore of adrenal ferredoxin.

PMID- 4370595
TI  - [The pathogenic microflora in edible fish].

PMID- 4370596
TI  - [The problem of malnutrition in Africa. Experiences in the Ivory Coast].

PMID- 4370597
TI  - Some properties of Ascaris suum allergen A.

PMID- 4370598
TI  - [The radiological diagnosis of carcinoids (author's transl)].

PMID- 4370599
TI  - Case records of the Massachusetts General Hospital. Weekly clinicopathological
      exercises. Case 48-1974.

PMID- 4370601
TI  - [New results of vitamin D research].

PMID- 4370600
TI  - Host responses to infectious bovine rhinotracheitis virus. III. Isolation and
      immunologic activities of bovine T lymphocytes.

PMID- 4370602
TI  - Fine structure of the adrenal gland in the duck (Anas platyrhynchos).

PMID- 4370603
TI  - [The synthesis of 3-thiolpyridine 2-sulfonic acid].

PMID- 4370604
TI  - [The toxins of Clostridium perfringens type C].

PMID- 4370606
TI  - [The value of photographic subtraction for angiography of bone and soft tissue
      tumours (author's transl)].

PMID- 4370605
TI  - [Low unit hCG determination with Highgonavis: a study of the hCG low level stage
      and treatment of chorionic tumor].

PMID- 4370607
TI  - [The Klippel-Trenaunay and Parkes-Weber syndromes, a practical and therapeutic
      classification, based on angiographic findings (author's transl)].

PMID- 4370608
TI  - Poly(riboadenylic acid) and adjacent nucleotides in Rous sarcoma virus RNA.

PMID- 4370609
TI  - Host-cell reactivation in mammalian cells. IV. Cell culture conditions affecting
      virus survival.

PMID- 4370610
TI  - Drug-induced phospholipidosis.

PMID- 4370611
TI  - Cell-mediated immunity to varicella-zoster virus: in vitro lymphocyte responses.

PMID- 4370612
TI  - Drug-receptor-related stereoselectivities in fat cells.

PMID- 4370613
TI  - Dose-response analysis of angiotensin- and renin-induced drinking in the cat.

PMID- 4370614
TI  - Post-transfusion hepatitis in a London hospital: results of a two-year
      prospective study. A report to the M.R.C. Blood Transfusion Research Committee by
      the Medical Research Council Working Party on Post-Transfusion Hepatitis.
AB  - Seven hundred and sixty-eight patients were seen and tested at frequent intervals
      after transfusion of whole blood. Eight patients were judged to have developed
      icteric or anicteric post-transfusion viral hepatitis, an incidence of 1%. Five
      were icteric and four of these were hepatitis B antigen (HB Ag) positive; two of
      these four died. One of the fatal cases and one non-fatal HB Ag positive case had
      received HB Ag positive blood. Two other antigen-positive patients had received
      blood or plasma or both which had not been tested for antigen.Thirty-five
      patients showed conspicuous or sustained elevations of alanine transaminase
      without clinical features of hepatitis.Four were positive for HB Ag but had not
      received antigen positive blood.Two who had received antigen positive blood
      remained antigen negative, but one developed hepatitis B antibody (HB Ab).Two
      other patients were also transfused with plasma.Five had serological evidence of
      cytomegalovirus (CMV) infection accompanying the enzyme changes.One patient who
      had received HB Ag positive blood remained antigen-negative and showed no
      abnormalities.Five patients who became HB Ag positive, although they had been
      given antigen-negative blood, remained clinically and biochemically
      well.Cytomegalovirus primary infection or reactivation occurred in another 32
      patients; five had isolated, transient enzyme rises, one other was associated
      with a drug-induced focal liver necrosis and 26 showed no enzyme changes. Epstein
      Barr virus infections, one of which was associated with a transient upset of
      enzyme activity, were detected in five patients. There were no cases of post
      perfusion syndrome.

PMID- 4370615
TI  - Visna-maedi in sheep.

PMID- 4370616
TI  - Destabilization of membranes with chaotropic ions.

PMID- 4370617
TI  - [Metabolic activity of the male genital tract in Cercocebus lunulatus and
      Erythrocebus patas: effect of castration and replacement therapy].

PMID- 4370618
TI  - Surface proteins of the erythrocyte membrane. Effect of aging.

PMID- 4370619
TI  - Intracellular activity of medullary respiratory neurons.

PMID- 4370620
TI  - Extracellular toxins of Pseudomonas aeruginosa.

PMID- 4370622
TI  - Intracisternal inclusions in nerve cells of cat ventromedial hypothalamic
      nucleus.

PMID- 4370621
TI  - Avenaciolide inhibition of anion transport in mitochondria.

PMID- 4370623
TI  - Characteristic ultrastructural changes in organs of newborn mice infected with
      EMC virus.

PMID- 4370624
TI  - Characterization and comparison of rabbit blastokinin produced under various
      physiological and experimental conditions.

PMID- 4370625
TI  - Characterization of the fraction obtained from the CNS of Jimpy mice by a
      procedure for myelin isolation.

PMID- 4370627
TI  - Characterization of Bacillus polymyxa amylase as an exo-acting(1 leads to 4)
      alpha-D-glucan maltohydrolase.

PMID- 4370626
TI  - Characterization of the insulin and somatomedin-C receptors in human placental
      cell membranes.

PMID- 4370628
TI  - Degradation of oil shale by sulfur-oxidizing bacteria.
AB  - Approximately 40% of oil shale can be solubilized by the action of sulfur
      oxidizing bacteria. Thiobacillus thiooxidans and Thiobacillus concretivorous are
      equally effective in solubilization. Continuous leaching experiments show that
      this process can be completed within 14 days. The growth of Thiobacillus and the
      production of acid were measured under several conditions. Almost all of the
      CaMg(CO(3))(2) was removed by this process, leaving a complex of silica and
      kerogen that could be burned as low-energy fuel. The silica-kerogen complex had
      not yet been biologically degraded.

PMID- 4370629
TI  - Circadian variation in human urinary cyclic AMP and the effect of different diets
      on this rhythm.

PMID- 4370630
TI  - Intradiaphragmatic cyst: a diagnostic challenge.

PMID- 4370631
TI  - Estradiol receptor in the human fallopian tube.

PMID- 4370632
TI  - Estradiol receptors in the oviduct and uterus of the rabbit.

PMID- 4370633
TI  - Leukaemogenic effect of repeated inoculations with small doses of Tennant virus
      in BALB-c mice.

PMID- 4370634
TI  - The aggregation of rabbit polymorphonuclear leucocytes: effects of antimitotic
      agents, cyclic nucleotides and methyl xanthines.

PMID- 4370635
TI  - [Renal osteodystrophy].

PMID- 4370636
TI  - Spinal pathways for cortical influences on lumbar motoneurons in rats.

PMID- 4370637
TI  - Spinal transmission of autonomic processes.

PMID- 4370638
TI  - Isovaleric acid as a precursor of odd numbered iso fatty acids in Tetrahymena.

PMID- 4370640
TI  - [Localization of mitochondrial alcohol dehydrogenase in Candida tropicalis].

PMID- 4370639
TI  - Mammalian acyl carrier protein. Dissociation of the acyl carrier protein subunit
      from dog liver fatty acid synthetase complex.

PMID- 4370641
TI  - A team approach to a disease survey on an aboriginal island (Orchid Island,
      Taiwan). V. Arboviral, rickettsial and brucella antibodies on Orchid Island.

PMID- 4370642
TI  - [Dream content study in schizophrenic patients by REMP--awakening technique
      (author's transl)].

PMID- 4370643
TI  - Glutamate dehydrogenase activity related to histopathological grade of
      hepatocellular carcinoma in man.

PMID- 4370644
TI  - Monoaminergic enzymes other than MAO.

PMID- 4370645
TI  - Monoamines and the regulation of vigilance and sleep.

PMID- 4370646
TI  - Neuraminidase treatment of adrenal cells increases their response to cholera
      enterotoxin.

PMID- 4370647
TI  - Neuraminidase: its effect on synaptic transmission.

PMID- 4370648
TI  - Intramitochondrial localization of arginase appearing in chicken liver upon
      starvation.

PMID- 4370649
TI  - The anatomy and physiology of the oviduct.

PMID- 4370650
TI  - Manganese in photosynthetic oxygen evolution. I. Electron paramagnetic resonance
      study of the environment of manganese in Tris-washed chloroplasts.

PMID- 4370651
TI  - Methanesulfonic acid derivative of p,p'-diaminodiphenylsulfone. II.
      Pharmacokinetics and availability of parental drug in rabbit.

PMID- 4370652
TI  - Cholangiocarcinoma: a clinicopathologic study of five cases with ultrastructural
      observations.

PMID- 4370653
TI  - Mechanically self-induced muzzle alopecia in mice.

PMID- 4370654
TI  - Mechanism of stimulation of murine type-C RNA tumor virus production by
      glucocorticoids: post-transcriptional effects.
AB  - We have previously shown that dexamethasone stimulates production of type-C virus
      from seemingly normal murine fibroblasts (BALB/3T3) and from transformed (Kirsten
      sarcoma-leukemia virus) nonproducing cells (BALB/K3T3) induced by 5
      iododeoxyuridine. In this report, we further examine the mechanism of this effect
      by using BALB/K3T3 cells. Several observations suggest that this effect is post
      transcriptional. The optimal stimulation by dexamethasone is obtained when
      dexamethasone is given 24 to 48 h after 5-iododeoxyuridine induction. Although
      this effect is late, time course experiments suggest that dexamethasone does not
      act to promote release of preformed virions. The stimulation by dexamethasone is
      blocked when cells are treated with cordycepin (3'-deoxyadenosine) during the
      first 24 h of induction, but not when cordycepin is added later. Conversely,
      interferon, which inhibits virus production, interferes with dexamethasone when
      it is added late or after removal of the steroid. The results of molecular
      hybridization experiments show that there is no detectable increase in Kirsten
      sarcoma-leukemia virus-specific RNA in dexamethasone-treated cells (with or
      without 5-iododeoxyuridine). The results of the time course studies, and the
      cordycepin, interferon, and hybridization experiments, suggest that the effect of
      dexamethasone on type-C virus production in this system is post-transcriptional.

PMID- 4370655
TI  - Mechanisms by which activated normal macrophages destroy syngeneic rat tumour
      cells in vitro. Cytokinetics, non-involvement of T lymphocytes, and effect of
      metabolic inhibitors.

PMID- 4370657
TI  - Mechanisms of blood-vascular reactions of the primate lung to acute endotoxemia.

PMID- 4370656
TI  - Mechanisms for development of diabetic hypertriglyceridemia in streptozotocin
      treated rats. Effect of diet and duration of insulin deficiency.
AB  - A combined ultrastructural and functional approach was employed to define the
      effects of duration of diabetes and of diet on various aspects of lipid
      metabolism in rats with severe streptozotocin (SZ)-induced insulin deficiency.
      Plasma triglyceride (TG) levels rose to a mean of 479 mg/100 ml 24 h after SZ
      administration in rats eating a fat-free, high carbohydrate diet as compared to a
      mean of 324 mg/100 ml in rats eating a high fat diet. These changes were
      associated with a commensurate increase in hepatocyte Golgi very low density
      lipoprotein (VLDL) content, but only a small increase in estimates of VLDL-TG
      secretion rate (post-Triton WR 1339 increment in plasma TG level). Although these
      findings are consistent with the thesis that VLDL-TG synthesis and secretion are
      increased 24 h after administration of SZ, it seemed unlikely that the observed
      increase in VLDL-TG secretion could entirely account for the severity of the
      hypertriglyceridemia. Thus, although lipoprotein removal rate was not measured
      directly, it was necessary to postulate that a defect in VLDL-TG removal was also
      present at this stage. Hypertriglyceridemia was still present 7 days later, only
      in this instance plasma TG levels were higher in rats eating the high fat diet (a
      mean of 589 mg/100 ml, as compared to 263 mg/100 ml). Rats with diabetes of 7-day
      duration had a 50% decrease in both TG entry rate and hepatocyte Golgi complex
      VLDL content, irrespective of diet. Thus, there was no evidence of increased VLDL
      TG secretion in chronic insulin deficiency. In this instance, although not
      assessed directly, it was necessary to postulate that the hypertriglyceridemia in
      chronically insulin-deficient rats is due entirely to a defect in lipoprotein
      removal, involving both dietary and endogenous fat.

PMID- 4370659
TI  - [Melanoderma as a side effect of cortisone depot therapy].

PMID- 4370658
TI  - Mechanisms of inflammation.

PMID- 4370660
TI  - The antiviral activity of some related benzo(b)thiophene derivatives. I. Initial
      screening tests.

PMID- 4370661
TI  - Ocular malformations in chick embryo resulting from diminished intraneural
      pressure.

PMID- 4370662
TI  - Preparation of impermeable ghosts and inside-out vesicles from human erythrocyte
      membranes.

PMID- 4370663
TI  - Preparation of isolated fat cells and fat cell "ghosts"; methods for assaying
      adenylate cyclase activity and levels of cyclic AMP.

PMID- 4370665
TI  - Comparative studies of viral infections of the developing forebrain. I.
      Pathogenesis of rat virus and bluetongue vaccine virus infections in neonatal
      hamsters.

PMID- 4370664
TI  - Comparative immunogenicity of irradiated, neuraminidase treated, and fused cells
      of a strain-restricted sarcoma.

PMID- 4370666
TI  - Comparative studies of viral infections of the developing forebrain. II. Electron
      microscopic studies of rat virus and bluetongue vaccine virus infections.

PMID- 4370667
TI  - Suprarenal cortical reserve capacity in Kwashiorkor.

PMID- 4370668
TI  - Univariate and multivariate models for evaluating long-term changes in
      neurobiological development, maturity and aging.

PMID- 4370669
TI  - Comparison between effects of cyclic AMP, dibutyryl cyclic AMP and luteinizing
      hormone on ovarian glycolysis.

PMID- 4370670
TI  - Comparison of adenylate kinase from liver and muscle of normal mice and those
      with an hereditary muscular dystrophy.

PMID- 4370671
TI  - Comparison of antigenicity of hepatoma cells, normal liver cells, foetal liver
      cells and chemically damaged liver cells in guinea-pigs immunized with hepatomata
      using the macrophage migration inhibition test.
AB  - The macrophage migration inhibition test has been used to study the immune
      responses of guinea-pigs immunized with injections of whole cells of both an
      allogeneic and a syngeneic hepatoma grown as established cell lines in tissue
      culture.A clear dose-response relationship between tumour cell concentration and
      migration inhibition was seen in immunized animals and no significant migration
      inhibition was seen in control animals. There was no cross reaction between the
      two tumours used. There was no cross reaction between whole isolated normal liver
      cells and tumour cells, or between foetal liver cells and tumour cells. Whole
      isolated liver cells from carbon tetrachloride damaged livers caused some degree
      of migration inhibition in both normal and immunized guinea-pigs but, taking this
      into account, they did not appear to cross react with hepatoma cells.

PMID- 4370673
TI  - Urinary cyclic adenosine monophosphate excretion in diabetes insipidus of
      childhood. Effect of vasopressin and chlorpropamide.

PMID- 4370672
TI  - Comparison of the fractional post-coital test with the Sims-Huhner post-coital
      test.

PMID- 4370674
TI  - Urinary excretion of adenosine 3' :5'-cyclic monophosphate in depressive illness.

PMID- 4370676
TI  - Primary linitis plastica carcinoma of the colon.

PMID- 4370675
TI  - Primary hyperparathyroidism. Preoperative evaluation and correlation with
      surgical findings.

PMID- 4370677
TI  - Primary malignant hemangioendothelioma of the liver. Report of a successful case
      of resection and review of the Japanese literature.

PMID- 4370678
TI  - Primary reninism, a surgically curable form of hypertension.

PMID- 4370679
TI  - Primary sequence of U-1 nuclear ribonucleic acid of Novikoff hepatoma ascites
      cells.

PMID- 4370680
TI  - Urinary steroid dynamics after a single dose of metyrapone.

PMID- 4370681
TI  - [A case of bilateral glomus tumor].

PMID- 4370682
TI  - [A case of leiomyosarcoma of the upper small intestine and accompanying jejuno
      jejunal invagination].

PMID- 4370683
TI  - [A case of parapharyngeal tumor of neurogenic origin].

PMID- 4370684
TI  - [A case of thymic tumor with hypercorticism].

PMID- 4370685
TI  - [3 cases of paraneoplastic syndromes in ORL].

PMID- 4370686
TI  - [2 cases of polyneuropathy caused by glue sniffing].

PMID- 4370687
TI  - [2 cases of Abrikosov's tumor of the larynx].

PMID- 4370688
TI  - [Breast cancer and estrogen receptor: from the standpoint of surgical hormone
      therapy].

PMID- 4370689
TI  - Ultrastructural and biochemical studies of the isolated fibrillar component of
      nucleoli from Novikoff hepatoma ascites cells.

PMID- 4370690
TI  - Ultrastructural changes in the nervous system after chronic exposure to
      halothane.

PMID- 4370691
TI  - Ultrastructural effects of dietary galactoflavin on mouse hepatocytes.

PMID- 4370692
TI  - Ultrastructural evolution of experimentally induced lipid inclusions in rat and
      mouse hepatocytes indicative for the recovery of livers from effects of
      benzidamine and triacetyloleandomycin.

PMID- 4370693
TI  - Ultrastructural features of papillomatosis and carcinoma of nipple ducts. The
      significance of myoepithelial cells and basal lamina in benign, "questionable,"
      and malignant lesions.

PMID- 4370694
TI  - Ultrastructural observation of possible nerve endings in rat sebaceous gland.

PMID- 4370695
TI  - Ultrastructural observations on the spinal cords of piglets affected with
      congenital tremor type AIV.

PMID- 4370696
TI  - Ultrastructure and three-dimensional organization of synaptic glomeruli in rat
      somatosensory thalamus.

PMID- 4370697
TI  - Ultrastructure of the lamina propria in the ovine seminiferous tubule.
      Development and some endocrine considerations.

PMID- 4370698
TI  - Ultrastructure of Michaelis-Gutmann body. A study of a case of testicular
      malacoplakia.

PMID- 4370699
TI  - An easy radioimmunological microassay of renin activity, concentration and
      substrate in human and animal plasma and tissues based on angiotensin I trapping
      by antibody.

PMID- 4370700
TI  - [Metasynchronous and synchronous neoplasms with metastases in a 47-years-old
      woman (author's transl)].

PMID- 4370701
TI  - Neonatal changes in the concentration of rat liver cyclic AMP and of serum
      glucose, free fatty acids, insulin, pancreatic, and total glucagon in man and in
      the rat.

PMID- 4370702
TI  - Neonatal keratitis due to herpes virus hominis type i infection.

PMID- 4370703
TI  - Neonatal plasma lipids as measured in cord blood.
AB  - The status of cord blood screening of plasma lipids is reviewed, emphasizing the
      problems associated with the diagnosis of familial hyperlipoproteinemia (HLP),
      particularly type II (hyperbetalipoproteinemia), in the neonate. For 2937
      neonates in this study the mean +/- standard deviation (SD) of plasma cholesterol
      was 70.3 +/- 16.9 mg/dl. The mean triglyceride level of 1805 neonates was 39.6 +/
      19.3 mg/dl. The mean level of beta-cholesterol in 240 neonates was 34.3 +/- 10.9
      mg/dl and the correlation between total and beta-cholesterol was high (r=0.89).
      By convention, the upper limit of normal was defined as the mean + 2 SD, and
      these levels for total cholesterol, triglyceride and beta-cholesterol were 100,
      80 and 55 mg/dl respectively. Only by careful follow-up of hyperlipidemic
      neonates can the incidence of HLP and the worth of early diagnosis be assessed.

PMID- 4370704
TI  - Repeated examinations, using the laparotomy sampling technique, of the gastro
      intestinal microflora of baboons fed a natural or a synthetic diet.

PMID- 4370706
TI  - Isolation and characterization of two distinct types of HVJ (Sendai virus)
      spikes.

PMID- 4370707
TI  - Radiation effects on NAD-and DNA-metabolism in mouse spleen.

PMID- 4370705
TI  - Isolation and characterization of rifampin-resistant and streptolydigin-resistant
      mutants of Bacillus subtilis with altered sporulation properties.
AB  - Mutants of Bacillus subtilis with altered deoxyribonucleic-dependent ribonucleic
      acid polymerase activity have been isolated and characterized. These mutants,
      selected as strains resistant to rifampin or streptolydigin, demonstrate drug
      resistant in vitro ribonucleic acid synthesis. Sporeforming ability and support
      of phage infection are altered in many of the mutants. Mutations to rifampin and
      streptolydigin resistance have been located on the B. subtilis chromosome and
      ordered relative to the markers cysA14 and str.

PMID- 4370708
TI  - Isolation of hen's egg yolk very low density lipoproteins by DEAE-cellulose
      chromatography.

PMID- 4370710
TI  - Isolation of modified liver lysosomes.

PMID- 4370709
TI  - Isolation of kidney lysosomes.

PMID- 4370711
TI  - Isolation of myelin from nerve tissue.

PMID- 4370713
TI  - Isolation of plasma membranes from rat and mouse livers and hepatomas.

PMID- 4370712
TI  - Isolation of nuclei from liver and other tissues.

PMID- 4370714
TI  - Isolation of rat liver plasma membrane fragments in isotonic sucrose.

PMID- 4370715
TI  - Variation of serotype in strains of Bordetella pertussis.
AB  - The four main serotypes of Bordetella pertussis (1, 2, 3; 1, 2; 1, 3; 1) undergo
      spontaneous variation involving loss or gain of antigen 2 or antigen 3. By serial
      subculture from single colonies on charcoal-blood-agar medium, we have detected
      loss-mutations from type 1, 2, 3 to 1, 2 or 1, 3, and from type 1, 2 to type 1.
      Likewise we have found gain-mutations from type 1 to 1, 2 or 1, 3, and from 1, 2
      to 1, 2, 3.These mutations apparently occur with a high frequency in some
      strains. Other strains have a lower mutation-rate and are more stable
      antigenically. We have not detected, by this method, either gain- or loss
      mutations from the type 1, 3 strains that we have tested.These findings offer an
      explanation for the changes in serotype that occur during the course of a
      pertussis infection in the child and in the marmoset. They also constitute a
      warning on the possible antigenic instability of laboratory strains, especially
      relevant in the production, absorption and testing of diagnostic antisera and in
      the preparation of pertussis vaccine.

PMID- 4370716
TI  - Isolation of ACTH-induced protein from adrenal perfusate.

PMID- 4370717
TI  - Formation of 5'-nucleotides of 6-methylmercaptopurine ribonucleoside in human
      tissues in vitro.

PMID- 4370718
TI  - Radiation therapy in bronchiolar-alveolar cell carcinoma: a case report.

PMID- 4370720
TI  - Isolation, identification, and characterization of six bovine picornavirus
      isolates.

PMID- 4370721
TI  - Variations of cytotoxic antibodies to cells with herpes simplex virus antigens in
      women with progressing or regressing cancerous lesions of the cervix.

PMID- 4370719
TI  - [Fixation with aldehydes for morphological and cytochemical studies (author's
      transl)].

PMID- 4370722
TI  - Chelator-sensitive in chloroplast electron transport.

PMID- 4370723
TI  - The background to Arthur Harden's discovery of cozymase.

PMID- 4370724
TI  - [Diabetic disease. Etiopathogenesis--clinical classification].

PMID- 4370725
TI  - Amoebic liver abscess--a clinical study.

PMID- 4370726
TI  - Solubilization of membrane-associated tumour-specific antigens by beta
      glucosidase.

PMID- 4370727
TI  - Antibiotic susceptibility testing of Pseudomonas aeruginosa: selection of a
      control strain and criteria for magnesium and calcium content in media.

PMID- 4370728
TI  - Inhibition of cytochrome c oxidase by hydrophobic metal chelators.

PMID- 4370729
TI  - Inhibition of growth of gonadal dependent structures by arginine vasotocin and
      purified bovine pineal fractions in immature mice and hamsters.

PMID- 4370730
TI  - Inhibition of Flac transfer by the fin+ I-like plasmid R62.
AB  - Flac mutants have been isolated in Escherichia coli K-12 which carry dominant
      mutations resulting in insensitivity to transfer inhibition by the Fin(+) I-like
      plasmid R62. These mutants were still sensitive to transfer inhibition by the
      fin(+) F-like plasmid R100 and, conversely, FlactraO(-) and traP(-) mutants,
      which are insensitive to R100 inhibition, were still sensitive to R62. The sites
      of action of the two inhibition systems are therefore different. Furthermore,
      inhibition by R62, unlike R100, did not require an F-specified product. Like
      R100, R62 prevented transfer, pilus formation, and surface exclusion and,
      therefore, probably inhibits expression of the transfer operon traA through traI.
      However, R62 was different from R100 in inhibiting transfer of J-independent
      mutants, indicating that its effect on the transfer operon is probably direct
      rather than via traJ. This is consistent with the different sites of action of
      the two inhibition systems. None of the Flac mutants overproduced pili in the
      absence of R62, although one mutant differing from those described above showed
      increased levels of transfer and surface exclusion.

PMID- 4370732
TI  - [Problems of late paralysis of the peripheral nerves].

PMID- 4370731
TI  - [Problems of ambulatory pharmacotherapy. 5. Chemotherapy of non-specific urinary
      tract infections].

PMID- 4370733
TI  - Antibodies to herpes-simplex virus in the cerebrospinal fluid of patients with
      herpetic encephalitis.

PMID- 4370734
TI  - Antibodies to Epstein-Barr virus and some other herpesviruses in patients with
      sarcoidosis, pulmonary tuberculosis and erythema nodosum.

PMID- 4370735
TI  - Metabolic adaptation of spiny mice (Acomys cahirinus) transferred from the desert
      to laboratory diets.

PMID- 4370736
TI  - Metabolic effects of cortisol and corticotrophins in the Australian brush-tailed
      opossum, Trichosurus vulpecula (Kerr).

PMID- 4370737
TI  - Metabolic regulation by multifunctional glucose-6-phosphatase.

PMID- 4370738
TI  - Metabolic studies on 125I-labeled baby hamster kidney cell plasma membranes.

PMID- 4370739
TI  - Metabolism of iodinated very low density lipoprotein in the rat. Autoradiographic
      localization in the liver.

PMID- 4370740
TI  - Metabolism of plasma triglycerides in endogenous hypertriglyceridemia.

PMID- 4370741
TI  - Foodborne disease surveillance: Washington State.

PMID- 4370742
TI  - The bovine respiratory disease complex.

PMID- 4370743
TI  - A rubredoxin-like mononuclear FeS4 derivative of adrenal iron-sulfur protein
      (adrenodoxin).

PMID- 4370744
TI  - Cerebrocerebellar communication systems.

PMID- 4370745
TI  - L-Ribulokinase from an initiator constitutive mutant.
AB  - The N-terminal sequence of l-ribulokinase (EC 2.7.1.16) isolated from an
      initiator constitutive (araI(-)) mutant is identical to wild-type kinase,
      indicating that the I(c) mutation probably lies outside of kinase structural gene
      araB.

PMID- 4370746
TI  - 99mTc pyrophosphate for diagnostic bone imaging.

PMID- 4370747
TI  - Radical treatment of recurrent cytosarcoma phylloides.
AB  - Malignant cystosarcoma phylloides is a rare breast cancer which frequently recurs
      locally before metastasizing. Local recurrence of cystosarcoma phylloides is
      unlike adenocarcinoma of the breast since it does not necessarily indicate
      systemic metastases; and, therefore, aggressive surgery can cure a number of
      patients with locally recurrent tumor. The present report is an extreme example
      of a patient with locally recurrent malignant cystosarcoma phylloides, and it
      illustrates the value of radical surgery in controlling this disease which had
      previously recurred 21 times. Fifteen months following sternal resection, the
      patient enjoys her longest tumor-free interval in 16 years.

PMID- 4370748
TI  - Two cases of chemodectoma of the carotid body.

PMID- 4370749
TI  - [Placental syncytiotrophoblast in tissue culture: study of its secretions and its
      cyclic AMP].

PMID- 4370750
TI  - A receptor mediating sexual differentiation?

PMID- 4370751
TI  - [Biochemical aspects of epilepsy].

PMID- 4370752
TI  - Bronchial carcinoma. A retrospective analysis of 2200 patients.

PMID- 4370753
TI  - Cytochrome oxidase activity in isolated giant cell of the reticular formation
      from the rat brain stem following carbon monoxide intoxication (Cartesian micro
      diver technique).

PMID- 4370754
TI  - [Succinate dehydrogenase activity of cytoplasmic and mesosomic membranes during
      sporulation of B. subtilis. Enzymatic analysis and cytochemical study].

PMID- 4370755
TI  - Principles of treatment of different types of parotid tumors.

PMID- 4370756
TI  - Capacitation in vitro of rabbit spermatozoa with cyclic adenosine monophosphate
      and human follicular fluid.

PMID- 4370757
TI  - The clinical effects of CI 744 in chinchillas, Chinchilla villidera (Laniger).

PMID- 4370758
TI  - The control of aldosterone secretion in nephrectomized man.

PMID- 4370759
TI  - The coordination of sterically hindered bases to metalloporphyrins.

PMID- 4370760
TI  - Endocrine evaluation and indications for surgery of functional pituitary
      adenomas.

PMID- 4370761
TI  - Direct binding of corticosterone and estradiol to rat liver nuclear non-histone
      proteins.

PMID- 4370762
TI  - Direct determination of molar ratios of various chemical constituents in
      endotoxic glycolipids in silicic acid scrapings from thin-layer chromatographic
      plates.

PMID- 4370763
TI  - Effect of aging, organ allografting, and surgical stress on rat thymus histidine
      decarboxylase activity.

PMID- 4370764
TI  - Effect of beta-propiolactone inactivation of polyoma virus on viral functions.
AB  - Polyoma virus was inactivated by treatment with beta-propiolactone. T-antigen
      production, polyoma-RNA synthesis, induction of host DNA synthesis (measured by
      incorporation of labeled thymidine into the cell culture), and in vitro
      transforming ability were inactivated to a similar degree by various beta
      propiolactone concentrations (0.25% beta-propiolactone reduced these functions
      approximately 96%), whereas plaque-forming ability and the ability of the virus
      to replicate its DNA and to synthesize capsid antigen were inactivated by a given
      concentration of beta-propiolactone to a much greater degree (0.25% beta
      propiolactone led to a reduction of plaque-forming ability of over 8 logs). The
      significance of these data and their relationship to previously published
      experiments are discussed.

PMID- 4370765
TI  - Effect of calcium ions on steroid-binding spectra and pregnenolone formation in
      rat-adrenal mitochondria.

PMID- 4370766
TI  - Effect of cysteine on the survival of mice with transplanted malignant thymoma.

PMID- 4370767
TI  - Effect of different solid metals and metallic pairs on human sperm motility.

PMID- 4370768
TI  - Effect of glucose on the fruiting body formation and adenosine 3',5'-cyclic
      monophosphate levels in Coprinus macrorhizus.
AB  - The formation of fruiting bodies in the monokaryotic fis(c) strain and a dikaryon
      of Coprinus macrorhizus was inhibited by growth in high-glucose media. In high
      glucose media the characteristic burst of adenosine 3',5'-cyclic monophosphate
      (cAMP) accumulation during fruiting-body formation was absent. Enzymatic activity
      assays revealed that mycelia grown in high-glucose media contained relatively
      lower amounts of adenylate cyclase and cAMP-phosphodiesterase than mycelia grown
      in low-glucose media. The synthesis of inducible d-serine deaminase and
      tryptophanase was repressed in high-glucose media. A mutant (gluR) in which the
      glucose repression of fruiting-body formation is affected was isolated by
      selection in high-glucose media. The mutation caused the cAMP levels to be no
      longer affected by glucose and affected ability to synthesize the inducible d
      serine deaminase and tryptophanase. The gluR mutant was partially dominant in
      dikaryons. It is suggested that cAMP may play important roles in inducing
      fruiting bodies and in controlling inducible enzyme synthesis in C. macrorhizus.

PMID- 4370769
TI  - Effect of inflammation upon human gingival oxidative metabolism.

PMID- 4370771
TI  - Effect of intraventricular norepinephrine on neuron activity in the medial
      forebrain bundle during self-stimulation behavior.

PMID- 4370770
TI  - Effect of inhibitors of proteolytic enzymes on the growth of normal and polyoma
      transformed BHK cells.

PMID- 4370772
TI  - Effect of manganese extraction on oxygen generation and EPR signal II in spinach
      chloroplasts.

PMID- 4370773
TI  - Effect of pentobarbital and sodium hydroxybutyrate on central mechanisms
      regulating vascular tone.

PMID- 4370774
TI  - Effect of peritubular infusion of angiotensin II on rat proximal nephron
      function.

PMID- 4370775
TI  - Effect of pharmacological agents on human keratinocyte mitosis in vitro. I.
      Inhibition by adenine nucleotides.

PMID- 4370776
TI  - Effect of polyinosinic-polycytidylic acid in dogs experimentally infected with
      infectious canine hepatitis virus.

PMID- 4370777
TI  - Effect of pregnancy on cytoplasmic and mitochondrial enzymes in human and animal
      myometrium.

PMID- 4370778
TI  - Effect of secretagogues on membrane parameters of adenohypophysial cells.

PMID- 4370779
TI  - Effect of sleep-wake cycle reversal on luteinizing hormone secretory pattern in
      puberty.

PMID- 4370780
TI  - Effect of tumor-promoting phorbol esters on the normal and the isoproterenol
      elevated level of adenosine 3',5'-cyclic monophosphate in mouse epidermis in
      vivo.

PMID- 4370781
TI  - Effect of various dietary fats on the size and distribution of lymph fat
      particles in rat.

PMID- 4370782
TI  - Effect of xanthothricin on the respiratory chain.

PMID- 4370784
TI  - Effect of TSH on iodine metabolism and intermediary metabolism in tissue from
      patients with Graves' disease.

PMID- 4370783
TI  - Effect of zinc deficiency from day 18 of gestation and-or during lactation on the
      development of some rat brain enzymes.

PMID- 4370785
TI  - Effect of 1,3-butanediol on hepatic fatty acid synthesis and metabolite levels in
      the rat.

PMID- 4370786
TI  - Effect of 2-nitrosonaphthalene on bacteria and bacteriophage.

PMID- 4370787
TI  - Selected recent vistas in bone pathology.

PMID- 4370788
TI  - Induction of aspermatogenesis in guinea pig through immunization with lactate
      dehydrogenase-x isozyme.

PMID- 4370790
TI  - Detection of sequence heterology by use of the N. Crassa nucleases.

PMID- 4370789
TI  - Detection of neoplastic lesions with radiogallium(67Ga citrate). Clinical
      statistical report on 125 cases.

PMID- 4370791
TI  - Induction of the postsynaptic membrane.

PMID- 4370792
TI  - Detection of trophoblast specific antigen in normal and neoplastic trophoblast.

PMID- 4370793
TI  - Infections of swine with pseudorabies virus and enteroviruses: laboratory
      confirmation, clinical and epizootiologic features.

PMID- 4370794
TI  - Defective immune responses and malignancy.

PMID- 4370796
TI  - Selective radioprotection in extracellular space.

PMID- 4370795
TI  - Selective measurement of two lipase activities in postheparin plasma from normal
      subjects and patients with hyperlipoproteinemia.
AB  - An assay has been developed for specific measurement of two different lipase
      activities in postheparin plasma. Lipoprotein lipase, derived from extrahepatic
      sources, is measured as protamine-inactivated lipase activity; hepatic lipase
      activity is protamine-resistant under the conditions of this assay. In 100 normal
      subjects, both enzyme activities were noted to be related to age and sex.
      Protamine-resistant lipase, which comprised 46-95% of the total activity, was
      highest in men over 18. Protamine-inactivated lipase activity was greatest in
      younger males and was age-correlated in women, doubling between the second and
      sixth decades. In 12 patients with hyperchylomicronemia, including five
      previously shown to have familial type I hyperlipoproteinemia, protamine
      inactivated lipase activity was markedly reduced, whereas protamine-resistant
      lipase was below normal in only 1. The results were not due to lack of plasma
      activator, presence of plasma inhibitor, or diet, and the deficiency was not
      overcome by increasing the provoking dose of heparin from 10 U to 75 U/kg. Mean
      values for both lipase activities were not reduced in 32 other patients with
      hyperchylomicronemia, nine with "floating beta" lipoproteins (type III
      hyperlipoproteinemia), and 23 with hyperprebetalipoproteinemia (type IV). Mean
      protamine-resistant lipase activity was below normal in a group of four women
      with hypothyroidism, in whom protamine-inactivated lipase was not reduced. Both
      of the lipase activities were capable of hydrolyzing lipid in very low-density
      lipoproteins, but the relative rate of hydrolysis of chylomicrons by protamine
      resistant lipase was markedly limited. These results indicate the importance of
      distinguishing between lipases of hepatic and extra-hepatic origin in the
      measurement of postheparin lipolytic activity.

PMID- 4370797
TI  - Defective simian virus 40 genomes: isolation and growth of individual clones.

PMID- 4370798
TI  - [Electron microscopic changes in rat hypophysis following adrenalectomy and ACTH
      administration. 1. Glandular lobe].

PMID- 4370799
TI  - [Electron microscopic study of differentiation of receptor cells in the sturgeon
      olfactory epithelium].

PMID- 4370800
TI  - [Electrophysiological studies of n-hexane polyneuropathy].

PMID- 4370801
TI  - Effects of alpha- and beta-receptor blocking agents on catecholamine and 5
      hydroxytryptamine induced peroxidase and amylase secretion from guinea pig
      submandibular gland.

PMID- 4370802
TI  - Effects of buffers and pH on in vitro binding of 67Ga by L1210 leukemic cells.

PMID- 4370803
TI  - Effects of clofibrate on mitochondrial function.

PMID- 4370804
TI  - Effects of cyclic neucleotide monophosphates (cAMP, cGMP, cIMP, dibutyryl-cAMP)
      on transtubular net fluxes in rat kidneys.

PMID- 4370805
TI  - Effects of dose on the induction of  dominant-lethal mutations and heritable
      translocations with ethyl methanesulfonate in male mice.
AB  - Genetic damage by ethyl methanesulfonate (EMS) in male mice was measured at doses
      ranging from 50 to 300 mg/kg with dominant-lethal mutations and reciprocal
      translocations as endpoints. No appreciable increase in dominant-lethal mutations
      was detected following a dose of 100 mg/kg. Dominant lethals induced by EMS were
      convincingly detected only after a dose of 150 mg/kg, but in the translocation
      experiment an increase in the genetic effect was detectable at the 50 mg/kg dose.
      It is likely that dominant lethals had also been induced at the 50 and 100 mg/kg
      doses, but were not detected due to the relative insensitivity of the
      dominant..lethal procedure. Thus, for detection of low levels of EMS-induced
      chromosome breakage, translocations are a much more reliable endpoint than are
      dominant-lethal mutations. A procedure for large-scale screening of induced
      translocations is described.-The dominant-lethal dose-response curve, plotted on
      the basis of living embryos as a percentage of the control value, is clearly not
      linear as it is markedly concave downward. Similarly, the translocation dose
      response curve showed a more rapid increase in the number of translocations with
      dose than would be expected on the basis of dose-square kinetics. It is clear for
      both of these endpoints that the effectiveness of EMS in inducing chromosome
      breakage is proportionately much lower at low doses.

PMID- 4370806
TI  - Effects of dose on the induction of dominant-lethal mutations with
      triethylenemelamine in male mice.
AB  - Dose effects of triethylenemelamine (TEM) in the induction of dominant-lethal
      mutations were studied at the early spermatozoon, midspermatid and spermatocyte
      stages. The pattern of effects on spermatocytes, unlike midspermatids and early
      spermatozoa, indicated possible cytotoxic damage, so for the determination of TEM
      dose-response curves in the induction of genetic damage only the data for
      midspermatids and early spermatozoa were used. The TEM dose-effect curves for
      those two stages differ markedly from ethyl methanesulfonate (EMS) dose-effect
      curves. Beginning with the lowest doses at which significant effects are
      observed, there is a considerably more rapid increase in dominant-lethal effects
      with dose of EMS than TEM. Another marked difference between the two compounds is
      in the ratio of the genetically effective dose (as measured by dominant-lethal
      mutations) to the lethal dose. The ratio is 1:100 for TEM and only 1:3.5 for EMS;
      thus, TEM is mutagenic far below its toxic level. Obviously, these results have
      important implications not only for our understanding of the nature of chemical
      induction and recovery of chromosomal aberrations but also for the practical
      problems of evaluating the mutagenic effects of chemicals.

PMID- 4370807
TI  - Effects of gonadotrophins, dibutyryl cyclic AMP and prostaglandin E2 on amino
      acid transport and glycolysis in isolated rat corpora lutea.

PMID- 4370808
TI  - Effects of intraventricular infusions of ACTH1-24 and ACTH4-10 on LH release,
      ovulation and behavior in the rabbit.

PMID- 4370809
TI  - Effects of papaverine derivatives on cyclic 3',5'-AMP phosphodiesterase and
      relaxation of rabbit ileum.

PMID- 4370810
TI  - Effects of progesterone and four synthetic progestagens on sodium balance and the
      renin-aldosterone system in man.

PMID- 4370811
TI  - Effects of pH and enzyme inhibitors on apparent generation of angiotensin I in
      human plasma.

PMID- 4370812
TI  - Effects of sympathetic stimulation on facial muscle contractions.

PMID- 4370813
TI  - Effects of tiletamine on spinal cord synaptic transmission.

PMID- 4370815
TI  - Effects of DMSO on vacuole formation, contractile vacuole function, and nuclear
      division in Tetrahymena pyriformis GL.

PMID- 4370814
TI  - Defects of two temperature-sensitive lysyl-transfer ribonucleic acid synthetase
      mutants of Bacillus subtilis.
AB  - Two temperature-sensitive mutants (lysS1 and lysS2) of the lysyl-transfer
      ribonucleic acid synthetase (l-lysine:tRNA ligase [adenosine 5'-monophosphate],
      EC 6.1.1.6) of Bacillus subtilis have been isolated. Although protein synthesis
      is inhibited in both mutants at the restrictive temperature (42 to 45 C), the
      mutants remain viable in a minimal medium. In comparison with the wild-type lysyl
      tRNA synthetase, the l-lysine-dependent exchange of [(32)P]pyrophosphate with
      adenosine 5'-triphosphate (ATP) for both mutant enzymes is decreased. The lysS1
      enzyme is completely defective in the ATP-dependent attachment of l-lysine to
      tRNA, whereas the lysS2 enzyme has 3- to 10-fold reduced levels of this activity.
      Temperature-resistant transformants have wild-type enzyme levels, whereas partial
      revertants to temperature resistance have varied levels of enzyme activity. The
      attachment and exchange activities of the lysS2 enzyme are more heat labile in
      vitro than the wild-type enzyme, as is the attachment activity of a partial
      revertant of the lysS1 mutant. The lysS1 and the lysS2 lysyl-tRNA synthetases
      have higher apparent K(m) values for lysine and ATP, in both the activation and
      the attachment reactions. The lysS2 enzyme has a V(max) for tRNA(lys) one-third
      that of the wild-type enzyme. Molecular weights of approximately 150,000 for the
      wild-type and lysS2 enzymes and approximately 76,000 for the lysS1 enzyme were
      estimated from sedimentation positions in sucrose density gradients assayed by
      the ATP-pyrophosphate exchange activity. We propose that the two mutations (lysS1
      and lysS2) directly affect the sites for exchange activity, but indirectly alter
      attachment activity as a consequence of defective subunit association.

PMID- 4370816
TI  - Effects on tumor growth in vivo by manipulation of the tumor immune response.

PMID- 4370818
TI  - Structural studies of avian myeloblastosis virus: absence of leukemogenic
      activity of the core component.

PMID- 4370817
TI  - Structural and functional heterogeneity of the murine cytomegalovirus genome.

PMID- 4370819
TI  - Structure of polysaccharides from the Polyporus tumulosus cell wall.

PMID- 4370820
TI  - Molecular and clinical pharmacology of psoriasis.

PMID- 4370821
TI  - Molecular and crystal structure of deoxyguanosine 5'-phosphate.

PMID- 4370822
TI  - Mixed mesodermal tumors of the corpus uteri.

PMID- 4370823
TI  - Mixed mesodermal tumour of the ovary.

PMID- 4370824
TI  - Mixed substrate experiments with human brain monoamine oxidase.

PMID- 4370825
TI  - Lipid transport and the availability of insulin.

PMID- 4370826
TI  - Rapid typing of herpes simplex virus strains using the indirect immunoperoxidase
      method.
AB  - The indirect immunoperoxidase technique with type-specific antisera was compared
      to kinetic neutralization for the typing of herpes simplex virus strains. There
      was complete agreement between the results obtained by kinetic neutralization and
      indirect immunoperoxidase. The indirect immunoperoxidase assay was far simpler to
      perform and interpret than the kinetic neutralization tests, and it offered a
      rapid means for the routine antigenic typing of herpes simplex isolates.

PMID- 4370827
TI  - [Fundamentals of per- and post-operative monitoring in surgery of organic
      hypoglycemia of pancreatic origin].

PMID- 4370828
TI  - Tinidazole in symptomatic intestinal amoebiasis.

PMID- 4370829
TI  - [Duodenal lymphangioma].

PMID- 4370830
TI  - Accidental infection of laboratory-reared Macaca mulatta with Trypanosoma cruzi.

PMID- 4370831
TI  - Ribodeoxyviruses and cancer.

PMID- 4370833
TI  - Age-dependent changes in the regulation of glycerolphosphate dehydrogenase in the
      rat brain and in a glial cell line.

PMID- 4370832
TI  - The dependence of evoked transmitter release on external calcium ions at very low
      mean quantal contents.
AB  - 1. The mean quantal content of the frog end-plate potential was examined under
      conditions that reduced evoked transmitter release to very low values.2. When the
      calcium concentration of the Ringer is reduced below 10(-4)M a deviation occurs
      from the fourth power dependence of the mean quantal content (m) on the calcium
      concentration such that more quanta are released than is expected from the
      behaviour of m at higher calcium concentrations.3. At 10(-5)M this extra quantal
      release is more than two orders of magnitude greater than that predicted by the
      fourth power relationship.4. The calcium dependence of very low values of m was
      studied in low calcium Ringer in which the calcium was buffered by either citrate
      or EDTA. It was found that in the fourth power dependence of m on the external
      calcium concentration changes rather suddenly to an approximately linear
      dependence.5. The inclusion of small concentrations of cobalt in the Ringer was
      found to reduce m to very low values even in the presence of millimolar
      concentrations of calcium.6. The fourth power dependence of m on the external
      calcium concentration at high values of m was unaffected by the presence of
      cobalt. At low quantal contents the transition to a linear dependence on external
      calcium was again seen, but was shifted to calcium concentrations that did not
      require buffering.7. The fourth power to linear transition is discussed in terms
      of its relevance to the relationship between m and the m.e.p.p. frequency.

PMID- 4370834
TI  - Acrodermatitis enteropathica. A clinical and biochemical survey.

PMID- 4370835
TI  - The detection of chemical mutagens using the L5178y-Asn-murine leukemia in vitro
      and in  a host-mediated assay.

PMID- 4370836
TI  - The determination of 2'-O-methylnucleosides in RNA.

PMID- 4370837
TI  - Triadic synaptic arrangements and their possible significance in the lateral
      geniculate nucleus of the monkey.

PMID- 4370838
TI  - [Studies of anti-foot-and-mouth disease vaccines for swine prepared with various
      adjuvants].

PMID- 4370839
TI  - [Studies on biologically active substances formed by bacilli. VI. Inhibitory
      effect of the serum calcium decreasing active lipoprotein alpha-I to cytolytic
      activity of surfactin (author's transl)].

PMID- 4370840
TI  - Sex differences in the elongation of the cranial base during pubescence.

PMID- 4370841
TI  - The differential diagnosis of neonatal hepatitis and biliary atresia.

PMID- 4370842
TI  - A modification in the response of human astrocytes to visna virus.

PMID- 4370843
TI  - Two distinct toxic proteins in Corynebacterium ulcerans.

PMID- 4370844
TI  - Two distinct types of secretory granules in an islet cell carcinoma associated
      with the Zollinger-Ellison syndrome.

PMID- 4370845
TI  - Pseudohomozygous type II hyperlipoproteinemia.

PMID- 4370846
TI  - Pseudomonas aeruginosa endocarditis in drug addicts.

PMID- 4370847
TI  - [Study of phagocytic activity of macrophages and their RNA content in mice-tumor
      carriers and isologous intact mice].

PMID- 4370848
TI  - [Study of the foot-and-mouth disease virus cultured on the BHK-21 cell line].

PMID- 4370849
TI  - Hemodynamic effects of acute and prolonged beta-adrenergic blockade in essential
      hypertension.

PMID- 4370850
TI  - Three cases of hepatoma.

PMID- 4370851
TI  - Three comparative techniques on tubo-plasty.

PMID- 4370852
TI  - Acute effects of alpha-methyldopa on mean blood pressure and plasma renin
      activity.

PMID- 4370853
TI  - [Side effects of antibiotic therapy (review of the literature)].

PMID- 4370855
TI  - House fly and Drosophila cell cultures as hosts for human enteroviruses.

PMID- 4370854
TI  - Trace elements in the human fallopian tube epithelium. Copper, zinc, manganese
      and potassium in the menstrual cycle.

PMID- 4370856
TI  - [Some general mechanisms of the effect of acupuncture (author's transl)].

PMID- 4370857
TI  - Acute leukemia-associated antigens.

PMID- 4370858
TI  - [Mode of action and regulation of aldosterone].

PMID- 4370859
TI  - [Case of insulinoma in forensic psychiatry].

PMID- 4370860
TI  - [Case of multiple familial glomus tumors].

PMID- 4370861
TI  - [Case of Lafora-body disease with interesting clinical symptoms].

PMID- 4370862
TI  - [Late results of surgical treatment in 100 patients with congenital vascular
      abnormalities].

PMID- 4370863
TI  - [Rare ventricular tumors].

PMID- 4370864
TI  - [Type 3 hyperlipoproteinaemia (broad-beta disease): diagnosis and quantitative
      isolation of the typical lipoprotein (author's transl)].

PMID- 4370865
TI  - Force-feeding effects on growth, carcass and blood composition in the young
      chick.

PMID- 4370866
TI  - Increased activity of a factor ("transferangiotensin") favoring the binding of
      angiotensin II to arterial wall in hypertension.

PMID- 4370867
TI  - Decreased response of plasma renin activity to orthostasis in diabetic patients
      with orthostatic hypotension.

PMID- 4370868
TI  - Increased transcapillary escape rate of albumin, IgG, and IgM during angiotensin
      II-induced hypertension in man.

PMID- 4370869
TI  - [Cerebral manifestation of congential cytomegalovirus infection (author's
      transl)].

PMID- 4370870
TI  - [Effect of adaptation to increased muscular activity on the sensitivity of the
      body to adrenaline].

PMID- 4370871
TI  - [Effect of adrenocorticotropic hormone on changes in the erythrocyte count, the
      amount of hemoglobin, the hematocrit value and the reticulocytes in suckling
      pigs].

PMID- 4370872
TI  - [Effect of cyclophosphamide and other homologous oxazaphosphorine-2-oxides on
      transplantation-immunologic reactions].

PMID- 4370873
TI  - [Effect of dehydration on certain functional aspects of the hypothalamo
      hypophyseo-adrenal axis].

PMID- 4370874
TI  - [Effect of prostaglandin on the kidney].

PMID- 4370875
TI  - [Effect of the temperature-humidity regime on some indices of carbohydrate
      metabolism in broilers with a varying content of tryptophan in the feed ration].

PMID- 4370876
TI  - [Effect of Krebs cycle components and glucose on the deamination of mono- and
      dinucleotides in brain mitochondrial fractions].

PMID- 4370877
TI  - Connection between the structural organization of the aortic baroreceptor zone
      and characteristics of the baroreceptors.

PMID- 4370878
TI  - [Detection of antibodies against Epstein's and Barr's virus in patients with
      carcinoma of the nasopharynx in the CSSR (author's transl)].

PMID- 4370879
TI  - [Effects of psychotropic drugs on the PGO-activities (PGO-activity in the REM
      sleep and reserpine-induced PGO-activity) (author's transl)].

PMID- 4370880
TI  - Soiled disposable diapers: a potential source of viruses.

PMID- 4370881
TI  - [Mixed tumors of the skin].

PMID- 4370882
TI  - Proceedings: A role for noradrenaline and cyclic AMP in prostaglandin E1 Fever.

PMID- 4370883
TI  - Proceedings: Assay of steroid hormone receptor in cancers, methodology and
      perspectives.

PMID- 4370884
TI  - Proceedings: Clinical value of predictive tests for advanced breast cancer.

PMID- 4370886
TI  - Proceedings: Effect of alpha-bungarotoxin and dendroaspis neurotoxins on
      acetylcholine responses of snail neurones.

PMID- 4370885
TI  - Proceedings: Correlation of serum levels of hepatoma D23 antigen, antibody and
      immune complexes with growth of transplanted tumours.

PMID- 4370887
TI  - Proceedings: Effects of angiotensin on fluid transport by rat jejunum in vivo.

PMID- 4370888
TI  - Proceedings: Further evidence that secretin stimulates pancreatic secretion
      through adenosine 3,'5'-monophosphate (cyclic AMP).

PMID- 4370889
TI  - Proceedings: Oestrogen and androgen receptors in human breast cancer.

PMID- 4370890
TI  - Proceedings: Oestrogen receptors in human breast cancer.

PMID- 4370891
TI  - Proceedings: Pathways for bulk outflow of aqueous humour and cerebrospinal fluid.

PMID- 4370892
TI  - Proceedings: Plasma cyclic AMP response to glucagon in thyroid disease.

PMID- 4370893
TI  - Proceedings: Possible role of mitochondria in transmitter release.

PMID- 4370894
TI  - Proceedings: Radioimmunoassay of HCG, alpha and beta subunits in cancer.

PMID- 4370895
TI  - Proceedings: The use of tissue culture in the screening of hormone sensitivity of
      endometrial carcinoma.

PMID- 4370896
TI  - The effect of acetyl-coenzyme A on phosphate-activated glutaminase from pig
      kidney and brain.
AB  - Phosphate-activated glutaminase (EC 3.5.1.2; l-glutamine amidohydrolase) purified
      from pig kidney and brain is activated by CoA and short-chain acyl-CoA
      derivatives. Acetyl-CoA is the most powerful activator (K(A) about 0.2mm). Acetyl
      CoA is maximally effective in the absence of other activating anions such as
      phosphate and citrate, and at low glutamine concentrations. The negative co
      operative substrate activation observed at pH7 becomes more pronounced in the
      presence of acetyl-CoA. Similarly to phosphate, acetyl-CoA produces at high
      protein concentrations a different type of activation, which is time-dependent,
      depends on protein concentration and is accompanied by an increase in the
      sedimentation coefficient. Acetyl-CoA, phosphate and citrate appear to have
      binding sites in common. No significant difference was observed between kidney
      and brain phosphate-activated glutaminase.

PMID- 4370897
TI  - The effect of antiestrogens on the nuclear binding of the estrogen receptor.

PMID- 4370898
TI  - The effect of repeated vaccination in an enzootic foot-and-mouth disease area on
      the incidence of virus carrier cattle.
AB  - A comparison was made of the incidence of foot-and-mouth disease virus ;carrier'
      cattle in an unvaccinated enzootic area and an area where routine 6-monthly
      vaccination with an inactivated vaccine had been carried out for 3-4 years. The
      incidence of carriers in the vaccinated area was 0.49% as compared to 3.34% in
      the non-vaccinated area. The results indicate that, provided the immune status of
      the vaccinated herd is maintained at a level sufficient to prevent outbreaks of
      clinical disease and the re-introduction of virus is prevented through livestock
      movement controls, it should be possible to eradicate the disease from an
      enzootic area through vaccination.

PMID- 4370899
TI  - The effect of sulfhydryl inhibitors on substrate oxidation and proline transport
      with membrane preparations from Mycobacterium phlei.

PMID- 4370902
TI  - The effects of a chronic limitation of sleep length.

PMID- 4370900
TI  - The effect of the hypocholesterolemic drug clofibrate on liver mitochondrial
      biogenesis. A role for neutral mitochondrial proteases.

PMID- 4370901
TI  - The effect of 3',5'-adenosine monophosphate on granulocyte adhesion.
AB  - Human granulocyte adhesion to glass capillary tubes was tested in the presence of
      agents that increase intracellular levels of cyclic 3',5'-adenosine monophosphate
      (cAMP). Adhesion was significantly reduced by 10(-3)-10(-4) M dibutyryl cAMP, 10(
      4)-10(-6) M prostaglandin E(1) (PGE(1)), 10(-4)-10(-6) M histamine, or 10(-3) M
      theophylline. Adhesion was not suppressed by 10(-4) M theophylline unless it was
      combined with PGE(1) or histamine. Eosinophil and basophil adhesion was
      especially sensitive to suppression by the above agents. These findings suggest
      that intracellular cAMP may play a role in regulation of adhesiveness of human
      basophils, eosinophils, and neutrophils.

PMID- 4370903
TI  - The effects of prolonged physiologic estradiol therapy on the maturation of
      hypogonadal teen-agers.

PMID- 4370904
TI  - Biodegradative L-threonine deaminase of Salmonella typhimurium.
AB  - The threonine deaminase formed under anaerobic conditions by Salmonella
      typhimurium is induced by l-serine and l-threonine, is catabolite repressible,
      requires cyclic adenosine 3',5'-monophosphate for its synthesis and adenylic acid
      for optimal activity, and is immunologically different from biosynthetic
      threonine deaminase.

PMID- 4370905
TI  - Protein kinase activity of bovine thyroid microsomes.

PMID- 4370906
TI  - Protein kinase and cyclic 3',5'-AMP: significance of binding and activation
      constants.

PMID- 4370907
TI  - Protein kinase in the sea urchin egg cortices. Its purification and
      characterization and some properties of an endogenous protein kinase in the
      cortices.

PMID- 4370908
TI  - Protein model refinement based on x-ray data.

PMID- 4370909
TI  - Protein secretion in the rat ventral prostate and the relation of golgi vesicles,
      cisternae and vacuoles, as studied by electron microscope radioautography.

PMID- 4370910
TI  - Epstein-Barr virus and human malignancies.

PMID- 4370911
TI  - Epstein-Barr virus from P3HR-1 cells grown in chemically defined medium.
AB  - A chemically defined medium, designated FCRC-1, supports the growth of P3HR-1
      cells and concomitant replication of infectious Epstein-Barr virus.

PMID- 4370912
TI  - Caffeine inhibition of dark-repair: lack of reversal by adenosine-(3'5')
      monophosphate.

PMID- 4370913
TI  - One-electron reactions in biochemical systems as studied by pulse radiolysis. VI.
      Stages in the reduction of ferricytochrome c.

PMID- 4370914
TI  - The electron transport system in the cochlear hair cell: the ultrastructural
      cytochemistry of respiratory enzymes in hair cell mitochondria of the guinea pig.

PMID- 4370915
TI  - The electrophoretic properties of some human blood cells. Effect of pH, ionic
      strength and antilymphocyte globulin.

PMID- 4370917
TI  - Subcellular fractionation of adipocytes.

PMID- 4370916
TI  - Subcellular distribution of transmitter-related enzyme activities in discrete
      areas of the rat dentate gyrus.

PMID- 4370918
TI  - Epidemiology of malignant neoplasms in children and juveniles in Warsaw Province
      between 1966-1970.

PMID- 4370919
TI  - [Attempts at the complex immunization of birds against fowl pox and infectious
      laryngotracheitis].

PMID- 4370920
TI  - Evidence against the presence of cyclic AMP and related enzymes in selected
      strains of Bacteroides fragilis.

PMID- 4370921
TI  - Evidence for the existence of a fully reduced state of molybdoferredoxin during
      the functioning of nitrogenase, and the order of electron transfer from reduced
      ferredoxin.

PMID- 4370922
TI  - Evidence for the formation of a gamma-phosphorylated glutamyl residue in the
      Escherichia coli acetate kinase reaction.

PMID- 4370923
TI  - Evidence for the modification of fructose 1,6-bisphosphatase by two distinct
      lysosomal proteases.

PMID- 4370925
TI  - [Intensification of antineoplastic immunity with the use of chemical
      heterogenization of tumor tissue antigens].

PMID- 4370924
TI  - Biogenic amines in cultured neuroblastoma and astrocytoma cells.
AB  - The presence of biogenic amines in cultured cells of mouse neuroblastoma C-1300
      (clone NB-2a) was suggested by fluorescence-microscope histochemistry. Incubation
      in media containing L-[(14)C]tyrosine and L-[(14)C]tryptophan for 24 h, followed
      by high-voltage electrophoresis, radiochromatogram scanning, and scintillation
      counting, confirmed the presence of [(14)C]dopamine, [(14)C]norepinephrine,
      [(14)C]epinephrine, [(14)C]serotonin, [(14)C]tyramine, and [(14)C]octopamine.
      Dopamine, norepinephrine, epinephrine, and serotonin were demonstrated
      spectrophotofluorometrically in concentrations, expressed as micrograms amine per
      milligram protein, of 1.19, 0.027, 0.038, and 0.148, respectively, for cells in a
      stationary growth phase. Fluorescence-microscope histochemistry also suggested
      the presence of biogenic amines in cultured astrocytoma cells (cell line C6).
      Spectrophotofluorometric assay of cells in a stationary growth phase demonstrated
      intracellular dopamine, norepinephrine, epinephrine, and serotonin in
      concentrations significantly lower than those of neuroblastoma cells.

PMID- 4370927
TI  - Content of adenosine 3'-5'-cyclic monophosphate in the pancreatic islets of mice
      with a hereditary defect of insulin secretion.

PMID- 4370926
TI  - [Extensive neuropathies caused by diphtheria. Apropos of the respiratory forms].

PMID- 4370928
TI  - [Recent research on the use of polyelectrolyte method for concentration of
      Enteroviruses from superficial waters].

PMID- 4370929
TI  - Segmental and lobar atrophy of the liver.

PMID- 4370930
TI  - Carpenter syndrome--acrocephalopolysyndactyly type II.

PMID- 4370931
TI  - Sequential renal lipid changes in weanling rats fed a choline-deficient diet.

PMID- 4370932
TI  - Concentration of enteric viruses from water with lettuce extract.
AB  - A method for recovering enteroviruses, adenovirus, and reovirus from water with
      lettuce extract is described. Lettuce extract at pH 8.5 was added to the sample
      and the pH was reduced stepwise with hydrochloric acid to 4.0 to 4.5. The
      flocculent lettuce-extract particles, and adsorbed virus, were readily removed
      from solution by low-speed centrifugation. Electron microscopy suggests that,
      under conditions suitable for adsorption, virus particles are coated with the
      lettuce-extract colloid.

PMID- 4370933
TI  - The enzymology of short-chain fatty acyl-coenzyme A synthetase from seeds of
      Pinus radiata. Kinetic studies and a proposed reaction mechanism.
AB  - 1. Short-chain fatty acyl-CoA synthetase from seeds of Pinus radiata was examined
      by acetate- and propionate-dependent PP(i)-ATP exchange. Reaction mixtures came
      to equilibrium almost instantly as judged by rates of exchange and analysis of an
      incubation mixture. 2. The activity of the enzyme was correlated with the
      concentration of MgP(2)O(7) (2-) but not with the concentration of Mg(2+), as
      judged by PP(i)-ATP exchange and fatty acyl AMP-dependent synthesis of ATP in the
      presence of PP(i). In PP(i)-ATP exchange assays, no clear relationship between
      activity and any single species of ATP was apparent. 3. High concentrations of
      fatty acid inhibited PP(i)-ATP exchange. PP(i)-dATP exchange was less than PP(i)
      ATP exchange at low concentrations of fatty acid, but at higher concentrations
      PP(i)-dATP exchange exceeded PP(i)-ATP exchange. The rate of synthesis of fatty
      acyl-CoA in the presence of dATP was less than with ATP. 4. ATP and propionate
      inhibited the synthesis of ATP from propionyl-AMP and PP(i). The inhibition by
      ATP was competitive with respect to propionyl-AMP and non-competitive with
      respect to PP(i). The inhibition by propionate was non-competitive with respect
      to propionyl-AMP and PP(i). 5. AMP was a competitive inhibitor of propionyl-AMP
      dependent synthesis of ATP and competitively inhibited propionate-dependent PP(i)
      ATP exchange when ATP was the variable substrate. 6. It was concluded that the
      first partial reaction catalysed by the enzyme is ordered; ATP is the first
      substrate to react with the enzyme and PP(i) is probably the only product
      released.

PMID- 4370934
TI  - Proteolytic processing in the biosynthesis of insulin and other proteins.

PMID- 4370935
TI  - Stereospecific (3H)(minus)-alprenolol binding sites, beta-adrenergic receptors
      and adenylate cyclase.

PMID- 4370936
TI  - Stereotactic anterior cingulate lesions for persistent pain: a report on 68
      cases.

PMID- 4370937
TI  - Nucleotide sequence of tRNA Cys from baker's yeast.

PMID- 4370938
TI  - Susceptibility of human gingival cells to some animal viruses.

PMID- 4370939
TI  - [Water and electrolyte metabolism in the regulation of blood pressure].

PMID- 4370940
TI  - Cancer in immunosuppressed experimental animals and human patients.

PMID- 4370941
TI  - Cancer risk in ulcerative colitis: its independence of luminal factors.

PMID- 4370942
TI  - Cancer- and organ-specificity of the carcinoembryonic antigen.

PMID- 4370943
TI  - Letter: A newly recognized inherited syndrome of dwarfism, craniosynostosis,
      retinitis pigmentosa, and multiple congenital malformations.

PMID- 4370944
TI  - Letter: Accurate quantitative estimation of lactate in whole blood.

PMID- 4370945
TI  - Letter: Cyclic AMP and cyclic GMP in gastric acid secretion.

PMID- 4370946
TI  - Letter: Cytomegalovirus and penta X syndrome.

PMID- 4370947
TI  - Letter: Hematologic and biochemical profiles in normal Demoiselle cranes.

PMID- 4370948
TI  - Letter: Interference by antibiotics in amino acid assays.

PMID- 4370949
TI  - Letter: Lead and intelligence.

PMID- 4370950
TI  - Letter: Nephroblastoma--genetic aspects.

PMID- 4370951
TI  - Letter: Nephrotic syndrome with oat-cell carcinoma.

PMID- 4370952
TI  - Letter: Prostaglandins in renal venous blood of essential hypertensive patients.

PMID- 4370953
TI  - Letter: Regulation of aldosterone biosynthesis by "angiotensin III".

PMID- 4370954
TI  - Letter: The dynamic voltage-transfer function for rod-bipolar cell transmission.

PMID- 4370955
TI  - Letter: Transmission of feline leukemia.

PMID- 4370956
TI  - Letter: Zoster in three children in family.

PMID- 4370957
TI  - Cooperativity in the inhibition of oxidative phosphorylation by
      chlorophenoxyisobutyrate.

PMID- 4370958
TI  - Temperature-sensitive mutants of vesicular stomatitis virus: comparison of the in
      vitro RNA polymerase defects of group I and group IV mutants.
AB  - When tested in vitro, certain temperature-sensitive (ts) mutants of vesicular
      stomatitis virus (VSV) belonging to complementation groups I and IV appear to
      have defects in the virion-bound polymerase. To obtain further information
      concerning the nature of these defects, representative mutants were dissociated
      by the method of S. Emerson and R. Wagner (1972), and their supernatant (S) and
      pellet (P) fractions were tested for transcriptase activity when combined with
      the P and S fractions, respectively, of VSV-HR virions. It was found that the S
      fractions from group I mutants tsW4, 11, 14, 15, and 28 were defective in
      transcriptase activity, whereas their P fractions were as active as those of VSV
      HR. On the other hand, the P fraction derived from virions of the group IV mutant
      tsW16B showed reduced activity at 25 C and very little activity at 38 C. These
      results suggest that our group I mutants, like those examined by D. Hunt and R.
      Wagner (1974), have a defect in the soluble transcriptase enzyme, whereas mutant
      tsW16B (group IV) has a defect in a sedimentable component required for
      transcriptase activity, possibly in the ribonucleoprotein template.

PMID- 4370959
TI  - Temperature-sensitive DNA polymerase from Rous sarcoma virus mutants.

PMID- 4370960
TI  - Differences in choroid plexus concentration of pertechnetate produced by varying
      time of pertechnetate administration and brain imaging.

PMID- 4370961
TI  - Different types of mutagenic effect of ethylmethanesulfonate on Drosophila
      melanogaster.

PMID- 4370962
TI  - Differential activation of biologically distinguishable endogenous mouse type C
      RNA viruses: interaction with host cell regulatory factors.

PMID- 4370963
TI  - Differential diagnosis of tumors of the salivary glands with radioactive
      isotopes.

PMID- 4370964
TI  - [Interference of sodium noramidopyrine methanesulfonate in the determination of
      plasma glucose and urea].

PMID- 4370965
TI  - Bacterial exoenzymes toxic for insects; proteinase and lecithinase.

PMID- 4370966
TI  - Bacterial interference between strains of S. aureus.

PMID- 4370967
TI  - [Experience in treatment of patients with chronic destructive pulmonary
      tuberculosis in a suburban tuberculosis hospital].

PMID- 4370968
TI  - [Experimental airborne A-Hong-Kong-1-68 (H3N2) influenza bronchopneumonia in Balb
      c mouse. Histopathological, immunofluorescent and ultrastructural studies
      (author's transl)].

PMID- 4370969
TI  - [Intermembrane electron transport in the absence of soluble carriers].

PMID- 4370970
TI  - [Determination of amylase activity in mixed salivary gland tumors].

PMID- 4370971
TI  - [Determination of basic hand of single helix by tilting device (author's
      transl)].

PMID- 4370972
TI  - Epidermolysis in a case of severe cytomegalovirus infection.

PMID- 4370973
TI  - Pattern of osmium deposition in the parietal cells of the stomach.
AB  - Parietal cells of the stomach of the hamster show extensive amounts of dense
      material in a variety of organelles after prolonged exposure to a solution of
      osmium tetroxide. Conspicuous amounts of reduced osmium compounds are evident
      within the granular endoplasmic reticulum, perinuclear cisterna, and vesicular
      elements of the Golgi complex. Dense material is also apparent within cristae of
      the mitochondria, the surface coat of the microvilli of the intracellular
      canaliculus, and vesicular elements of the multivesicular bodies. Multivesicular
      bodies, containing numerous small osmiophilic elements, are often seen
      surrounding and/or in close contact with mitochondria. The proximity of the
      multivesicular bodies to the mitochondria appears to be related to an autophagic
      process involving degradation of mitochondria. The distribution and intensity of
      the precipitates within the organelles of the parietal cells vary in different
      regions of the gastric glands. The findings of this study emphasize that cell
      structures other than the Golgi complex may contain large concentrations of
      reduced osmium compounds after prolonged exposure to a solution of osmium
      tetroxide.

PMID- 4370974
TI  - Concerning specificity of the influence of pentoxifylline on various cyclic AMP
      phosphodiesterases.

PMID- 4370975
TI  - Dispersion of central nervous system tumors. Correlation between clinical aspects
      and tissue culture studies.

PMID- 4370976
TI  - Properties and substrate specificity of some reactions catalysed by a short-chain
      fatty acyl-coenzyme A synthetase from seeds of Pinus radiata.
AB  - 1. Crude extracts of seeds of Pinus radiata catalysed acetate-, propionate-, n
      butyrate- and n-valerate-dependent PP(i)-ATP exchange in the presence of MgCl(2),
      which was apparently due to a single enzyme. Propionate was the preferred
      substrate. Crude extracts did not catalyse medium-chain or long-chain fatty acid
      dependent exchange. 2. Ungerminated dry seeds contained short-chain fatty acyl
      CoA synthetase activity. The activity per seed was approximately constant for 11
      days after imbibition and then declined. The enzyme was located only in the
      female gametophyte tissue. 3. The synthetase was purified 70-fold. 4. Some
      properties of the enzyme were studied by [(32)P]PP(i)-ATP exchange. K(m) values
      for acetate, propionate, n-butyrate and n-valerate were 4.7, 0.21, 0.33 and 2.1mm
      respectively. Competition experiments between acetate and propionate demonstrated
      that only one enzyme was involved and confirmed that the affinity of the enzyme
      for propionate was greater than that for acetate. CoA inhibited fatty acid
      dependent PP(i)-ATP exchange. The enzyme catalysed fatty acid-dependent
      [(32)P]PP(i)-dATP exchange. 5. The enzyme also catalysed the fatty acyl-AMP
      dependent synthesis of [(32)P]ATP from [(32)P]PP(i). Apparent K(m) (acetyl-AMP)
      and apparent K(m) (propionyl-AMP) were 57mum and 7.5mum respectively. The
      reaction was inhibited by AMP and CoA. 6. Purified enzyme catalysed the synthesis
      of acetyl-CoA and propionyl-CoA. Apparent K(m) (acetate) and apparent K(m)
      (propionate) were 16mm and 7.5mm respectively. The rate of formation of acetyl
      CoA was enhanced by pyrophosphatase. 7. It was concluded that fatty acyl
      adenylates are intermediates in the formation of the corresponding fatty acyl
      CoA.

PMID- 4370977
TI  - Properties of a phosphoprotein phosphatase from bovine heart with activity on
      glycogen synthase, phosphorylase, and histone.

PMID- 4370978
TI  - Properties of 3-hydroxy-3-methylglutaryl coenzyme A reductase solubilized from
      rat liver and hepatoma.

PMID- 4370979
TI  - [Hypertriglyceridemia and pancreatitis].

PMID- 4370980
TI  - Glomerular beta-lipoprotein in childhood renal diseases.

PMID- 4370982
TI  - Herpes encephalitis with catatonic stupor.

PMID- 4370981
TI  - Herpes encephalitis therapeutic considerations.

PMID- 4370983
TI  - Herpes genitalis and aseptic meningitis.

PMID- 4370984
TI  - Herpes genitalis and its relationship to cervical cancer.

PMID- 4370985
TI  - Herpes simplex lesions of the skin diagnosed by the immunofluorescence technique.

PMID- 4370986
TI  - Herpes simplex virus and human cytomegalovirus replication in WI-38 cells. II. An
      ultrastructural study of viral penetration.
AB  - An electron microscope study was carried out on the early minutes of herpes
      simplex virus (HSV) and cytomegalovirus (CMV) penetration into WI-38 cells. Both
      HSV and CMV entered cells either by fusion of the viral envelope with a limiting
      cell membrane, or via phagocytosis. Both fusion and phagocytosis occurred within
      3 min after the initiation of penetration. After fusion, the naked capsids of CMV
      free in the cytoplasm became coated with a fine, fibrillar material. CMV capsids
      thus coated retained a well-defined and easily identifiable morphology until the
      eclipse of visible viral particles between 1 and 1.5 days postinfection. In
      contrast, naked HSV capsids free in the cytoplasm were never coated. Rather,
      within minutes after penetration, they assumed a rounded, less regular outline,
      and were no longer detectable by 90 to 120 min postinfection. The free naked
      capsids of both viruses appeared to migrate across the cytoplasm toward the
      nucleus and to become located near nuclear pores. Both HSV and CMV capsids
      reached the nucleus as early as 5 min after the initiation of penetration. No
      further interaction with the nucleus could be documented. Particles were also
      consistently identified in the Golgi region. Phagocytosed particles generally
      remained within phagosomes, where they appeared to be degraded. However, stages
      were identified in what is believed to be the escape of enveloped viruses from
      phagosomes into the cytoplasm via fusion of their envelope with the phagosomal
      membrane.

PMID- 4370987
TI  - Herpes virus latency in spinal ganglia of mice without illness.

PMID- 4370989
TI  - Successful extraction of large intracaval isthmus of nephroblastoma.

PMID- 4370988
TI  - Herpes viruses and oncogenesis.

PMID- 4370990
TI  - Depression of cell-mediated immunity during acute infectious mononucleosis.

PMID- 4370991
TI  - Depression of human monocyte chemotaxis by herpes simplex and influenza viruses.

PMID- 4370992
TI  - Expression of purified mitochondrial poly(A)polymerase of hepatomas by an
      endogenous primer from liver..

PMID- 4370993
TI  - Progesterone and androgen receptors in non-flagellate germ cells of the rat
      testis.

PMID- 4370994
TI  - Cholesteryl ester metabolism in tissue culture cells. I. Accumulation in Fu5AH
      rat hepatoma cells.

PMID- 4370995
TI  - Nondestructive separation of rat liver rough microsomes into ribosomal and
      membranous components.

PMID- 4370996
TI  - Herpesvirus encephalitis and pulmonary sarcoidosis. A case report with necropsy
      findings.

PMID- 4370997
TI  - [Islet cell tumor. Different clinical forms demonstrated with 3 patients].

PMID- 4370998
TI  - Competitive protein-binding radioassay of urinary cortisol.

PMID- 4371000
TI  - EEG evaluation of a sleep recorder.

PMID- 4370999
TI  - Pasteur effect and phosphofructokinase.

PMID- 4371001
TI  - The eye and its disorders. 29. Diseases of the visual pathways.

PMID- 4371002
TI  - Purification and properties of an extracellular acid ribonuclease from
      Penicillium janthinellum.

PMID- 4371003
TI  - Purification and regulatory properties of fructose 1,6-diphosphatase from
      Hydrogenomonas eutropha.
AB  - Fructose diphosphatase of Hydrogenomonas eutropha H 16, produced during
      autotrophic growth, was purified 247-fold from extracts of cells. The molecular
      weight of the enzyme was estimated to be 170,000. The enzyme showed a pH optimum
      of 8.5 in both crude extracts and purified preparation. The shape of the pH curve
      was not changed in the presence of ethylenediaminetetraacetic acid. The enzyme
      required Mg(2+) for activity. The MgCl(2) saturation curve was sigmoidal and the
      degree of positive cooperativity increased at lower fructose diphosphate
      concentrations. Mn(2+) can replace Mg(2+), but maximal activity was lower than
      that observed with Mg(2+) and the optimal concentration range was narrow. The
      fructose diphosphate curve was also sigmoidal. The purified enzyme also
      hydrolyzed sedoheptulose diphosphate but at a much lower rate than fructose
      diphosphate. The enzyme was not inhibited by adenosine 5'-monophosphate but was
      inhibited by ribulose 5-phosphate and adenosine 5'-triphosphate. Adenosine 5'
      triphosphate did not affect the degree of cooperativity among the sites for
      fructose diphosphate. The inhibition by adenosine 5'-triphosphate was mixed and
      by ribulose 5-phosphate was noncompetitive. An attempt was made to correlate the
      properties of fructose diphosphatase from H. eutropha with its physiological role
      during autotrophic growth.

PMID- 4371004
TI  - Modification of diphtheria toxin by NAD.

PMID- 4371005
TI  - The fine structure of the lutein cells in the blue fox (Alopex lagopus) with
      special reference to the secretory activity during pregnancy.

PMID- 4371006
TI  - The fine structure of the ovarian follicle of Alloteuthis subulata Lam.
      (Mollusca, Cephalopoda).

PMID- 4371007
TI  - The flower pot technique of rapid eye movement (REM) sleep deprivation.

PMID- 4371009
TI  - [Perforation of the colon as a complication of contrast enemas (author's
      transl)].

PMID- 4371008
TI  - The foot-and-mouth disease virus subtype variants in Kenya.
AB  - The subtype variants found in Kenya in the past ten years have been studied. The
      type O and type SAT 2 subtypes have a distinct geographical distribution which
      appears to be associated with livestock movement patterns. The type A viruses
      have a greater tendency to antigenic variation and their geographical
      distribution is less distinct. In type C only minor differences exist between the
      three viruses studied.

PMID- 4371010
TI  - [Malformations of the femur: their spontaneous development].

PMID- 4371011
TI  - Wakefulness and REM sleep in human neonates.

PMID- 4371013
TI  - The general febrile respiratory form of infectious bovine rhinotracheitis in
      calves.

PMID- 4371012
TI  - Rat gastric mucosal cAMP following cholinergic and histamine stimulation.

PMID- 4371014
TI  - Cytogenetic study of primary tumors induced in the golden hamster by chemical and
      viral agents. Communication II. Karyotypic characteristics of tumors induced by
      the simian virus 40 (SV40) and the combined action of virus and 7,12
      dimethylbenzanthracene.

PMID- 4371015
TI  - Antigenic makeup of subcellular fractions of Trypanosoma cruzi.

PMID- 4371016
TI  - [Congenital seewaw nystagmus (author's transl)].

PMID- 4371017
TI  - Changes during development of mouse brain in the activities and subcellular
      distributions of creatine and adenylate kinases.

PMID- 4371018
TI  - Changes in intra-ovarian pressure in woman following the administration of
      luteinizing hormone-releasing hormone LH-FSH).

PMID- 4371020
TI  - Hypoglycemia: pathogenesis, diagnosis and treatment.

PMID- 4371021
TI  - Recognition by electrophoretic localisation of the extracellular products of
      selected strains of staphylococci.

PMID- 4371022
TI  - Assignment of the gene for galactokinase to human chromosome 17 and its regional
      localisation to band q21-22.

PMID- 4371023
TI  - Antagonism of dopamine-mediated inhibition in the nigro-striatal pathway: a mode
      of action of some catatonia-inducing drugs.

PMID- 4371024
TI  - Antagonism of morphine by beta-melanocyte-stimulating hormone and by
      tetracosactin.

PMID- 4371025
TI  - Antagonistic effect of methadone on steroidogenesis and the adenylate cyclase
      system in isolated rat adrenocortical cells.

PMID- 4371026
TI  - Energy-linked reactions in photosynthetic bacteria. IX. Pi-PPi exchange in
      Rhodospirillum rubrum.

PMID- 4371027
TI  - Lymph node metastasis as first manifestation of glioblastoma. Case report.

PMID- 4371028
TI  - [Phthalazines. X. On the reaction of 1-(methylsulfonyl)-phthalazine with Grignard
      reagents (author's transl)].

PMID- 4371029
TI  - [Exchangeable sodium and sodium space in some types of hypertension (author's
      transl)].

PMID- 4371030
TI  - [Mechanism of peripheral nerve involvement in alkyl mercury intoxication].

PMID- 4371031
TI  - On the association of some dermatoses with South American pemphigus foliaceus.

PMID- 4371032
TI  - On the electron transfer reaction between ferricytochrome c and ferrohexacyanide
      in the pH range 5 to 7.

PMID- 4371034
TI  - Is the neurotransmitter system abnormal in multiple sclerosis?

PMID- 4371033
TI  - On the extracellular synthesis of adenosine triphosphate by mammalian cells.

PMID- 4371035
TI  - On the origin of the genes for neoplasia: G.H.A. Clowes memorial lecture.

PMID- 4371036
TI  - On the problem of the origin of nerve terminals in the sympathetic ganglia.

PMID- 4371037
TI  - On the question of the primary acceptor in bacterial photosynthesis:manganese
      substituting for iron in reaction centers of Rhodopseudomonas spheroides R-26.

PMID- 4371038
TI  - On the relationship between cell division and cyclic adenosine-3',5'
      monophosphate in Escherichia coli.

PMID- 4371039
TI  - On the ultrastructure of the rat anococcygeus muscle.

PMID- 4371040
TI  - Epithelial inclusions in the vas deferens: an electron microscopic study.

PMID- 4371041
TI  - Biochemical and endocrine differences between normotensive and spontaneously
      hypertensive rats.

PMID- 4371043
TI  - [A chemical method for the determination of phospholipids in the amniotic fluid].

PMID- 4371044
TI  - Further studies on postsynaptic potential in masseteric motoneuron.

PMID- 4371045
TI  - Synthesis and secretion of fibrinogen and albumin by isolated rat hepatocytes.

PMID- 4371042
TI  - Biochemical and morphological characterization of azurophil and specific granules
      of human neutrophilic polymorphonuclear leukocytes.
AB  - Postnuclear supernates from homogenates of purified neutrophil polymorphonuclear
      leukocytes (PMNs) from human blood were fractionated by zonal sedimentation and
      isopycnic equilibration in sucrose gradients. The fractions were characterized
      biochemically by measuring protein content and the activities of eight enzymes.
      Selected fractions were further analyzed by electron microscopy. In both
      centrifugation systems, azurophil and specific granules could be resolved almost
      completely. Azurophil granules sediment three to four times faster than the
      specifics and have an average density of 1.23. They contain all the peroxidase of
      the cells, large portions of four lysosomal hydrolases, and about half of the
      total lysozyme, and therefore appear to be, in biochemical terms, very similar to
      the azurophil granules of rabbit PMNs. The specific granules, which have an
      average density of 1.19, contain the remaining half of the lysozyme but appear to
      be free of the other components of the azurophil granules, and of alkaline
      phosphatase. Isopycnic equilibration disclosed a minor lysosomal population,
      which strongly overlaps the specific granules, and made possible the
      identification of a membrane-fraction which is characterized by the presence of
      the thiol-sensitive acid 4-nitrophenyl phosphatase and of alkaline phosphatase.

PMID- 4371046
TI  - Synthesis of simian virus 40 DNA in isolated nuclei.

PMID- 4371047
TI  - Synthesis of some new semisynthetic penicillins.

PMID- 4371048
TI  - [Cushing's disease and genesis of the adrenocorticotrophic hormone].

PMID- 4371049
TI  - [Methods of regulating fertility. Endometrial biochemical changes].

PMID- 4371051
TI  - Psychological aspects of cardiac surgery. Psychiatric grand rounds.

PMID- 4371050
TI  - Morphological and cytological effects of carbenicillin on Pseudomonas
      pseudomallei.

PMID- 4371052
TI  - Morphology and X-ray sensitivity of rat glial cells after cytochalasin B
      treatment.

PMID- 4371053
TI  - Morphology of the aging brain, human and animal.

PMID- 4371054
TI  - N-(phosphonacetyl)-L-aspartate, a potent transition state analog inhibitor of
      aspartate transcarbamylase, blocks proliferation of mammalian cells in culture.

PMID- 4371055
TI  - Psychotropic drugs and some enzymes of energy metabolism.

PMID- 4371056
TI  - [Nephroblastoma (Wilm's tumor). European clinical research].

PMID- 4371057
TI  - Prophylactic use of antibiotics in preventing bovine respiratory disease complex.

PMID- 4371058
TI  - Staphylococcal sphingomyelinase (beta-hemolysin).

PMID- 4371059
TI  - Staphylococcal sphingomyelinase (beta-hemolysin).

PMID- 4371060
TI  - The hyperthermic effect of intracerebroventricular cholera enterotoxin in the
      unanaesthetized cat.
AB  - 1. Cholera enterotoxin was used to evaluate a possible role of endogenous cyclic
      AMP in production of hyperthermia. Injection of purified toxin (0.10-1.0 mug in
      0.10 ml.) into the lateral cerebral ventricle of unanaesthetized cats caused dose
      related hyperthermic responses. Heating the toxin for 40 min at 90 degrees C
      abolished its hyperthermic activity.2. Intraventricular administration of
      dibutyryl cyclic AMP (250-1000 mug) also caused hyperthermia which, however, was
      preceded by transient periods of hypothermia and/or excitation in about half of
      the tests.3. Paracetamol, indomethacin and sodium salicylate inhibited
      hyperthermic responses to cholera enterotoxin. Paracetamol and indomethacin also
      inhibited hyperthermia induced by dibutyryl cyclic AMP (sodium salicylate was not
      tested).4. It is likely that the hyperthermic effect of cholera enterotoxin in
      the cat is mediated via endogenous cyclic AMP and that the antipyretics inhibit
      this effect by an action subsequent to the increase in cyclic AMP.5. It is
      unlikely that prostaglandin-induced hyperthermia in the cat is mediated via
      cyclic AMP since these antipyretics do not inhibit this response to prostaglandin
      E(1).

PMID- 4371061
TI  - The hypothalamo-hypophysial system of the lamprey, Lampetra fluviatilis L. I. the
      neuohypophysis.

PMID- 4371062
TI  - Cardiac hypertrophy in spontaneously hypertensive rats.

PMID- 4371063
TI  - A trial of corticotrophin gelatin injection in acute optic neuritis.
AB  - The effect of a 30 day course of corticotrophin gelatin injections on the natural
      history of acute unilateral optic neuritis in 27 patients is reported. A further
      27 patients received inert injections in a double-blind control. Measurements
      were made on visual acuity, visual field, macular threshold, and colour vision,
      and the development of optic atrophy and other neurological episodes was
      recorded. No significant differences were found between treated and control
      groups at intervals up to two years from the start of the trial. The criteria for
      inclusion of patients are given and it is concluded that corticotrophin has no
      effect on the natural history of the condition as defined.

PMID- 4371064
TI  - [Facial paralysis of unknown origin. Testing for a viral etiology by antibody
      measurement].

PMID- 4371065
TI  - Ovarian hilus-cell tumours: their varying presentations.

PMID- 4371066
TI  - Ovarian neoplasms at the Chelsea Hospital.

PMID- 4371067
TI  - Amebiasis in a mental institution: serologic and epidemiologic studies.

PMID- 4371068
TI  - Possible higher valence states of cytochrome P-450 during oxidative reactions.

PMID- 4371069
TI  - A cribriform cylindroma with metastases.

PMID- 4371070
TI  - Cyclic adenosine monophosphate-dependent phosphorylation of specific fat cell
      membrane proteins by an endogenous membrane-bound protein kinase. Possible
      involvement in the regulation of insulin-stimulated glucose transport.

PMID- 4371071
TI  - Steric and electrostatic interactions in reactions of carbohydrates. III. Direct
      displacement of the C-2 sulfonate of methyl 4,6-o-benzylidene-3-o-methyl-2-o
      methylsulfonyl-beta-d-gluco-and-mannopyranosides.

PMID- 4371072
TI  - Cyclic AMP levels in Phycomyces during a response to light.

PMID- 4371073
TI  - Cyclic AMP mediates the concanavalin A agglutinability of mouse fibroblasts.
AB  - We have devised a quantitative way to measure the agglutination of cells which
      utilizes the size discrimination feature of an automatic particle counter. With
      this method we have studied the agglutinability by concanavalin A of 3T3 cells, a
      mutant of 3T3 cells (3T3cAMP(tcs)) in which cyclic AMP levels fall when the cells
      are subjected to temperature change or fresh serum, and L929 cells. We find with
      3T3cAMP(tcs) cells that low levels of cyclic AMP correlate with increased
      agglutinability and that high levels of cyclic AMP correlate with decreased
      agglutinability. Prior treatment of these cells with a cyclic AMP
      phosphodiesterase inhibitor or Bt(2)cAMP blocks the increase in agglutinability
      induced by temperature change. When 3T3 cells are treated with fresh serum, their
      agglutinability also increases although to a much smaller extent than with
      3T3cAMP(tcs) cells. Cells change their agglutinability very rapidly. Treatment of
      L929 cells for 15 min with 1-methyl-3-isobutyl xanthine at 1 mM decreases their
      agglutinability to the level of normal 3T3 cells. We conclude that in normal and
      transformed cells the level of cyclic AMP regulates agglutinability.

PMID- 4371074
TI  - Cyclic GMP and cyclic AMP levels in normal and transformed fibroblasts.

PMID- 4371075
TI  - Clinical antitumor activity and toxicity of streptozotocin (NSC-85998).

PMID- 4371076
TI  - Surgical aspects of amebiasis.

PMID- 4371077
TI  - Atypical blood lymphocytes in sarcoidosis: morphology, cytochemistry, and
      membrane properties.

PMID- 4371078
TI  - Atypical demyelinating disease.
AB  - A 17 year old girl died after an illness characterized by progressive mental
      deterioration and severe myoclonic jerks. Extensive pathological, virological,
      and immunological studies failed to support the diagnosis of subacute sclerosing
      panencephalitis but were compatible with disseminated demyelinating disease. The
      spinal fluid was positive for measles virus antibodies when examined by the
      fluorescent antibody technique, by complement fixation, and by haemagglutination
      inhibition tests, but the antibody titres were not high. The concentration of
      vaccinia antibody in the serum was consistent with that found in the general
      population and none was detected in the spinal fluid. Animal and tissue culture
      studies failed to disclose a viral agent, but pathological sections revealed
      perivascular cellular infiltration, demyelination, rare inclusion bodies, and
      multinucleated giant cells. Although these studies were not definitive, a record
      of procedures used and results obtained, both positive and negative, may be
      helpful to other investigators interested in defining more accurately the
      clinical features and the pathogenesis of these diseases.

PMID- 4371079
TI  - Physical properties of a dog liver and kidney cytosol protein that binds thyroid
      hormone.

PMID- 4371080
TI  - Physical protein regulation of adenylate kinases from muscle, liver, and
      hepatoma.

PMID- 4371081
TI  - Chemical structure of a modification of the Escherichia coli ribonucleic acid
      polymerase alpha polypeptides induced by bacteriophage T4 infection.

PMID- 4371082
TI  - Chemical synthesis and biological activity of 3-deoxy-1alpha-hydroxyvitamin D3 an
      analog of 1alpha,25-(OH)2-D3, the active form of vitamin D3.

PMID- 4371083
TI  - Clinical use of renin determinations.

PMID- 4371084
TI  - Application of a vidicon spectrometer for simultaneous flame-emission analysis
      for sodium and potassium in serum.

PMID- 4371085
TI  - Application of immune electron microscopy to the study of the antigenic
      relationships between three new human papovaviruses.

PMID- 4371086
TI  - [Dolichomega cerebral arteries in children].

PMID- 4371087
TI  - Corticosteroids: a direct effect at the neuromuscular junction.

PMID- 4371088
TI  - Corticotropin release during ECT in man.

PMID- 4371089
TI  - Prediction of the secondary structure of proteins using the helix-coil transition
      theory.

PMID- 4371090
TI  - [Vesicular stomatitis virus induced CO2 sensitivity in "Drosophila melanogaster".
      3. A study of different serotypes of the virus (author's transl)].

PMID- 4371091
TI  - Deamidation of glutaminyl and asparaginyl residues in peptides and proteins.

PMID- 4371092
TI  - President's address. Myasthenia gravis.

PMID- 4371093
TI  - Studies of serum lipoprotein concentrations in children: preliminary report.

PMID- 4371094
TI  - Studies of the regulation of colicin Ib synthesis. II. The synthesis of col Ib-P9
      specific RNA in vivo.

PMID- 4371095
TI  - Studies of NAD(H) conformations in solution: a new method using the PMR spectra
      of cobalt ion-dinucleotide complexes.

PMID- 4371096
TI  - Studies on the diagnostic value of an immunofluorescence test for EB virus
      specific IgM.
AB  - A modification of the test for EB virus/IgM introduced by Schmitz and Scherer
      (1972) is described. It is simple and gives reproducible results.EB virus/IgM was
      demonstrated in all but one case of infectious mononucleosis and in students with
      minor illness shown to have acquired EB virus/IgG recently. Unlike the EB
      virus/IgG, the IgM disappears within a few months. Although the Paul-Bunnell
      Davidsohn test is still the test of choice for the diagnosis of infectious
      mononucleosis, the EB virus/IgM test could be useful to establish a diagnosis of
      current or recent EB virus infection where the Paul-Bunnell-Davidsohn test was
      negative or equivocal.

PMID- 4371097
TI  - Studies on the effects of acetylcholine, epinephrine, dibutyryl cyclic adenosine
      monophosphate, theophylline, and calcium on the synthesis of myoglobin in muscle
      cell cultures estimated by radioimmunoassay.

PMID- 4371098
TI  - Studies on the growth and changes in metabolism of rats fed on carbohydrate
      deficient fatty acid-based diets supplemented with graded levels of maize starch.

PMID- 4371099
TI  - Studies on the in vitro adenylation of RNA by vesicular stomatitis virus.

PMID- 4371100
TI  - Studies on the inhibition of RNA synthesis by phalloidin in primary cultures of
      fetal cells.

PMID- 4371101
TI  - Studies on the mechanism of deacylation of aminoacyl-tRNAs by aminoacyl-tRNA
      synthetases in the absence of adenosine monophosphate and pyrophosphate.

PMID- 4371102
TI  - Studies on the stability of the hemagglutinating antibody of Entamoeba
      histolytica.

PMID- 4371103
TI  - Studies on the structure-activity relationships of synthetic LHRH analogs.

PMID- 4371104
TI  - Studies on 3,7-dimethyl-1-(5-oxo-hexyl)-xanthine(BL 191). I. Cyclic 3',5'
      nucleotide phosphodiesterase (PDE) and the inhibitory effect of BL 191 on PDE in
      rat brain and heart.

PMID- 4371105
TI  - Specific binding of growth hormone to thymocytes.

PMID- 4371106
TI  - Amplification of a circular segment of SV40 DNA.

PMID- 4371107
TI  - Calcification of selected strains of Streptococcus mutans and Streptococcus
      sanguis.
AB  - Nine strains of cariogenic Streptococcus mutans and two strains of Streptococcus
      sanguis were tested for their ability to form hydroxyapatite. The cells were
      examined by X-ray diffraction and electron microscopy for apatite crystals after
      growth in a synthetic calcification medium. Each of the test isolates, except for
      one strain of S. sanguis, produced intracellular mineral. Two strains of S.
      mutans formed both intra- and extracellular crystals. There was no apparent
      relationship between calcifiability and serotype.

PMID- 4371108
TI  - [Benign intraluminal stenosis of the oesophagus (author's transl)].

PMID- 4371109
TI  - [Malignant granuloma in animals in the course of experimental infection with reo
      I virus (author's transl)].

PMID- 4371110
TI  - Stability and enzyme separation: integral representation of the solutions.

PMID- 4371111
TI  - Stability studies and tumor uptake of a technetium-tetracycline complex.

PMID- 4371112
TI  - [Virilization of adrenal origin. Report of a case].

PMID- 4371113
TI  - [Capillaroscopic changes and disturbances of conductivity in motor fibers of
      peripheral nerves in diabetic children (author's transl)].

PMID- 4371114
TI  - [Optimally spaced after-treatment with multiplicative effect. A cancer therapy
      principle of universal character].

PMID- 4371115
TI  - Haemin and nicotinamide adenine dinucleotide requirements of Haemophilus
      influenzae and Haemophilus parainfluenzae.

PMID- 4371116
TI  - [Renin and sodium and the formation of vascular lesions in hypertension].

PMID- 4371117
TI  - Reagin synthesis in inbred strains of rats.

PMID- 4371118
TI  - [Renin-angiotensin system in hypertension].

PMID- 4371119
TI  - The inactivation of the acyl phosphatase activity catalyzed by the sulfenic acid
      form of glyceraldehyde 3-phosphate dehydrogenase by dimedone and olefins.

PMID- 4371120
TI  - Vaccination against infectious bovine rhinotracheitis may hamper export trade in
      breeding cattle.

PMID- 4371121
TI  - The incorporation of glucose into brain glycogen and the activities of cerebral
      glycogen phosphorylase and synthetase: some effects of amphetamine.

PMID- 4371122
TI  - [Cylindroma of the maxillary sinus].

PMID- 4371123
TI  - Guanine nucleotides and thiourea as modifiers of dynein ATPase and CTPase
      activity.

PMID- 4371124
TI  - Combined contrast and radionuclide angiography of the liver.

PMID- 4371126
TI  - The influence of calcium on the molecular mobility of fatty acid spin labels in
      phosphatidylserine and phosphatidylinositol structures.

PMID- 4371125
TI  - Cholinergic control by endogenous prostaglandins of cAMP accumulation under TSH
      stimulation in the thyroid.

PMID- 4371127
TI  - The influence of enzymes on the estrogen receptors of human uterus and breast
      carcinoma.

PMID- 4371128
TI  - [Meningo-encephalitic sarcoidic pseudo-tumor in a child: optical and electron
      microscopic study of a case].

PMID- 4371129
TI  - The inherited blood factors of the inhabitants of Southern Arabia.

PMID- 4371130
TI  - A clinical evaluation of aspiration of cysts of the breast.

PMID- 4371131
TI  - A clinicopathological review of 100 cases of primary malignant tumours of the
      liver.
AB  - One hundred cases of primary malignant tumour of the liver coming to necropsy in
      the period 1900-1969 have been reviewed. The overall tumour incidence was 0.46%
      of all necropsies. The overall tumour incidence in hepatic cirrhosis was 12.3%,
      but the corresponding male and female incidences were 17.5 and 4.4% respectively.
      There was no significantly increased tumour incidence in haemochromatosis. An
      increasing incidence of primary malignant tumours of the liver has been noted
      since 1940 and appears to be due to a corresponding increase in incidence of
      hepatic cirrhosis. Hepatocellular carcinomas outnumbered cholangiocarcinomas by 8
      to 1, were more common in males than females (6 to 1), and in 77% of cases
      occurred in cirrhotic livers. Tumours supervened as a complication of
      macronodular or predominantly macronodular cirrhotic patterns.

PMID- 4371132
TI  - Carcinomatous lymph nodes within breast parenchyma.

PMID- 4371133
TI  - The interaction of phospholipase C from Staphylococcus aureus and Clostridium
      perfringens with cell membranes.

PMID- 4371134
TI  - [Angiographic diagnosis of nesidioblastomas (author's transl)].

PMID- 4371135
TI  - [Angiographic findings in a retroperitoneal leiomyosarcoma].

PMID- 4371136
TI  - [Angiographic techniques for the demonstration of intracranial aneurysms
      (author's transl)].

PMID- 4371137
TI  - [Radioligand-receptor-assay of gonadotropin].

PMID- 4371138
TI  - Physiological characteristics of re-innervation of skeletal muscle in the mouse.
AB  - 1. Re-innervation of soleus was studied in the mouse after either crushing the
      sciatic nerve or re-implanting the nerve to soleus outside the original end-plate
      region.2. During the early stages of re-innervation subthreshold end-plate
      potentials (e.p.p.s) were recorded in muscle fibres in response to nerve
      stimulation. Later the e.p.p.s became large enough to evoke action potentials in
      muscle fibres.3. The rate of recovery of the release of acetylcholine (ACh) as
      estimated from the quantal content of e.p.p.s was faster when nerves re
      innervated the old end-plate region after nerve crush than after re-implantation
      so that new neuromuscular junctions were formed.4. During re-innervation soleus
      fatigued more rapidly than normal during repetitive nerve stimulation. The
      fatigue was due to failure of neuromuscular transmission associated with an
      impaired release of ACh.5. During re-innervation soleus was supersensitive to ACh
      until nerve stimulation was capable of evoking action potentials in muscle
      fibres.

PMID- 4371139
TI  - Physiological cyclic AMP in Drosophila.

PMID- 4371140
TI  - [Action of prostaglandin on adenyl cyclase--cyclic AMP system and its mechanism,
      with special reference to the thyroid gland].

PMID- 4371141
TI  - [Action of prostaglandin on the pituitary-adrenal system].

PMID- 4371142
TI  - [Action of the neomercazole and of the perchlorate ion on the normal human
      thyroid (author's transl)].

PMID- 4371143
TI  - Erosions of the petrous temporal bone.

PMID- 4371144
TI  - [Radionuclides in the diagnosis of space-requiring brain processes].

PMID- 4371146
TI  - [Peripheral neuropathy caused by drug in toxication--direct invasion by drugs and
      ultrastructural changes of the tissue].

PMID- 4371145
TI  - [Various peculiarities of the diagnosis of ventricular system tumors].

PMID- 4371147
TI  - Multiple control mechanisms underlie initiation of growth in animal cells.

PMID- 4371148
TI  - Multiple divergent copies of endogenous C-type virogenes in mammalian cells.

PMID- 4371149
TI  - Apolipoprotein B levels and altered lipoprotein composition in diabetes.

PMID- 4371151
TI  - Respiration for protection against cotton dust.

PMID- 4371150
TI  - Repair replication and photorepair of DNA in larvae of Drosophila melanogaster.
AB  - Repair replication of DNA has been studied in first instar larvae of Drosophila
      melanogaster with isopycnic centrifugation techniques. Larvae were fed BUdR,
      FUdR, streptomycin, penicillin, and Fungazone for two to four hours prior to
      exposure to UV, X-rays, MMS, or EMS. Feeding was continued for four hours in the
      presence of (3)HBUdR and DNA was isolated from whole larvae. Repair replication
      is stimulated by each of these agents. MMS is about 10 times as potent as EMS in
      stimulating repair synthesis. A dose of 200 ergs/mm(2) largely saturates the
      level of repair replication observed after UV irradiation. Repair replication
      rises between 0 and 80,000 R of X-rays before falling off. Semiconservative
      synthesis is seriously inhibited above a dose of 40,000 R of X-rays. Photorepair
      has been detected as a reduction in repair synthesis resulting from post
      irradiation exposure to photoreactivating light. The same treatment has no
      detectable effect on X-ray-stimulated repair replication. Repair replication is
      insensitive to the presence of caffeine or hydroxyurea during the final
      incubation, although semiconservative synthesis is strongly inhibited by these
      agents. A mixture of BUdR and (3)HTdR can be used to replace (3)HBUdR in
      detecting repair replication.

PMID- 4371152
TI  - Respiratory activities associated with mesosomal vesicles and protoplast
      membranes of Staphylococcus aureus.
AB  - Analysis of oxidase and dehydrogenase activities, cytochrome content of mesosomal
      vesicles, and protoplast membranes showed that the respiratory chain in
      Staphylococcus aureus is associated predominantly with the protoplast membranes.

PMID- 4371153
TI  - Of birds and mice and men: comments on the use of animal models and molecular
      hybridization in the search for human tumor viruses.

PMID- 4371154
TI  - Impaired autoregulation of blood flow and glomerular filtration rate in the
      isolated dog kidney depleted of renin.

PMID- 4371155
TI  - Requirement of thymus-derived theta-positive lymphocytes for rejection of DNA
      virus (SV 40) tumors in mice.

PMID- 4371156
TI  - Acquisition of chick cytosol thymidine kinase activity by thymidine kinase
      deficient mouse fibroblast cells after fusion with chick erythrocytes.
AB  - Chick-mouse heterokaryons were obtained by UV-Sendai virus-induced fusion of
      chick erythrocytes with thymidine (dT) kinase-deficient mouse fibroblast [LM(TK(
      ))] cells. Autoradiographic studies demonstrated that 1 day after fusion,
      [(3)H]dT was incorporated into both red blood cell and LM(TK(-)) nuclei of 23% of
      the heterokaryons. Self-fused LM(TK(-)) cells failed to incorporate [(3)H]dT into
      nuclear DNA. 15 clonal lines of chick-mouse somatic cell hybrids [LM(TK(-))/CRB]
      were isolated from the heterokaryons by cultivating them in selective
      hypoxanthine-aminopterin-thymidine-glycine medium. LM(TK(-)) and chick
      erythrocytes exhibited little, if any, cytosol dT kinase activity. In contrast,
      all 15 LM(TK(-))/CRB lines contained levels of cytosol dT kinase activity
      comparable to that found in chick embryo cells. Disk polyacrylamide gel
      electrophoresis and isoelectric focusing analyses demonstrated that the LM(TK(
      ))/CRB cells contained chick cytosol, but not mouse cytosol dT kinase. The LM(TK(
      ))/CRB cells also contained mouse mitochondrial, but not chick mitochondrial dT
      kinase. Hence, the clonal lines were somatic cell hybrids and not LM(TK(-)) cell
      revertants. The experiments demonstrate that chick erythrocyte cytosol dT kinase
      can be activated in heterokaryons and in hybrid cells, most likely as a result of
      functions supplied by mouse fibroblast cells.

PMID- 4371157
TI  - Cortisol dynamics in the adrenal venous effluent.

PMID- 4371158
TI  - The isolation and characterization of plasma membrane from cultured chicken
      embryo fibroblasts.

PMID- 4371160
TI  - The isolation of lung lamellar bodies.

PMID- 4371159
TI  - The isolation of anaerobic bacteria from wound swabs.
AB  - The isolation of anaerobic bacteria from routine wound swabs by three procedures
      was evaluated. Recovery of anaerobic organisms was doubled by immediate
      incubation of seeded plates, and the recovery could be further dramatically
      improved by the use of prereduced media, in conjunction with an anaerobic
      chamber. Recommendations for the treatment of swabs and cultures for anaerobic
      investigation are made.

PMID- 4371161
TI  - The isolation of lysosomes from brain.

PMID- 4371162
TI  - The isolation of outer and inner mitochondrial membranes.

PMID- 4371163
TI  - The isolation of strict anaerobes: the use of an anaerobic cabinet compared with
      a conventional procedure.

PMID- 4371164
TI  - Persistent infections with herpesviruses.

PMID- 4371165
TI  - Rabbit brain phosphofructokinase. Comparison of regulatory properties with those
      of other phosphofructokinase isozymes.

PMID- 4371167
TI  - [Solitary metastases of melanoblastoma in pancreatic insulinoma].

PMID- 4371166
TI  - Pituitary adenomas: factors in treatment.

PMID- 4371168
TI  - Sensitive in vivo assay for detection of murine leukemia viruses.
AB  - A test is reported for the in vivo detection of the replicative ability of murine
      leukemia viruses (MLV) in the BALB/c mouse strain. Growth in the spleen was
      assayed by the complement-fixation assay for MLV group-specific antigen after
      injection of newborn mice. Low doses of laboratory-derived and wild-type MLV from
      cell-culture and animal-grown sources were detected as early as 7 to 14 days
      postinoculation. The sensitivity of this in vivo test compared favorably with in
      vitro assays for MLV. In vivo detection of MLV replication was correlated with
      long-term oncogenicity.

PMID- 4371169
TI  - Calcitonin receptors on cultured human lymphocytes.

PMID- 4371170
TI  - In vitro association of unique species of cellular 4S RNA with 35S RNA of RNA
      tumor viruses.

PMID- 4371171
TI  - In vitro release of corticosteroids from adrenal glands of obese-hyperglycemic
      mice (gene symbol ob).

PMID- 4371172
TI  - In vitro transfer of cellular immunity against nasopharyngeal carcinoma using
      transfer factor from donors with Epstein-Barr virus antibody activity.

PMID- 4371173
TI  - Calcium binding to brain plasma membranes.

PMID- 4371174
TI  - Survival of Clostridium perfringens on chicken cooked with microwave energy.

PMID- 4371175
TI  - [Activity of certain oxidizing enzymes in the placenta of women with arterial
      hypotension].

PMID- 4371176
TI  - [Activity of glycolytic enzymes at different stages of the mitotic cycle of
      Ehrlich tumor cells].

PMID- 4371177
TI  - [Activity of phosphatases, transaminases and lactate dehydrogenase of mixed
      saliva in the use of stainless steel prostheses].

PMID- 4371178
TI  - Marek's disease virus and the herpesvirus of turkeys.

PMID- 4371179
TI  - Breakdown of intracellular NAD by streptococcal NAD--glycohydrolase EC 3.2.2.5.

PMID- 4371181
TI  - Cytokinins: formation of the nucleoside-5'-triphosphate in tobacco and Acer
      cells.

PMID- 4371180
TI  - The kinetics of formation and biological activity of native and hybrid molecules
      of human follicle-stimulating hormone.

PMID- 4371182
TI  - Basal cell adenoma of the salivary glands.

PMID- 4371183
TI  - Renal tubular localization of parathyroid hormone induced urinary cyclic
      adenosine 3',5'-monophosphate.

PMID- 4371184
TI  - The laboratory in the diagnosis and management of viral hepatitis.

PMID- 4371186
TI  - Modulation of cyclic-AMP synthesis in the cat superior cervical ganglion by short
      term presynaptic stimulation.

PMID- 4371185
TI  - Regulation of aldosterone synthesis.

PMID- 4371187
TI  - Regulation of muscle phosphorylase b kinase activity by inorganic phosphate and
      calcium ions.
AB  - The regulation of the activity of blowfly flight-muscle phosphorylase b kinase by
      P(i) and Ca(2+) was studied, and the actions of these effectors on the kinases
      from insect flight and rabbit leg muscles were compared. Preincubation of blowfly
      kinase with P(i) increased activity severalfold. The effect was concentration
      dependent, with an apparent K(m) of about 20mm, and time-dependent, requiring at
      least 10min for maximal activation. Neither ATP nor cyclic AMP was needed,
      suggesting that a protein kinase may not be involved. Maximal activation of the
      insect kinase required Mg(2+) in addition to P(i). The apparent K(m) for Mg(2+)
      was 3mm. Rabbit leg-muscle phosphorylase b kinase was slightly inhibited, rather
      than stimulated, by P(i), and was strongly inhibited by K(+), Na(+) and Li(+). At
      physiological concentrations, Ca(2+) activated the phosphorylase b kinases from
      both blowfly flight and rabbit leg muscles. However, the responses to Ca(2+) of
      the enzymes from the two tissues were different. The mammalian kinase had
      virtually no activity in the absence of Ca(2+), and showed a large increase in
      activity over a narrow range of Ca(2+) concentrations. Flight-muscle kinase had
      appreciable activity in the absence of Ca(2+), and had a smaller increase over a
      wide range of Ca(2+) concentration. The concentrations of Ca(2+) required for
      half-activation were 0.1 and 1mum for the blowfly and rabbit enzymes
      respectively. The pH-activity profiles of the non-activated, phosphate- and
      Ca(2+)-activated kinase revealed considerable enhancement of activity with
      little, if any, increase in the ratio of activities at pH6.8 to those at 8.2.
      These results are discussed in relation to the mechanism coupling contraction to
      glycogenolysis and to the biochemical distinction between asynchronous and
      synchronous types of muscle.

PMID- 4371188
TI  - Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma tissue
      culture cells by serum lipoproteins.

PMID- 4371189
TI  - [Nuclear bodies in the viviparous lizard, Lacerta vivipara Jacquin:
      ultrastructural study in the embryo and after birth].

PMID- 4371191
TI  - Indolent mucoid carcinoma of stomach.
AB  - In a review of 574 cases of gastric carcinoma, 50 (8.7%) proved to be mucoid
      using defined microscopic criteria. Three histological types were recognized:
      pure signet-ring cell carcinoma (three cases); tumour of mixed pattern (41
      cases); and an easily recognized, well differentiated type (six cases). This last
      group pursued an indolent course and had a mean survival time of nine years
      compared with mean survival times in the other two groups of five and 18 months
      respectively.

PMID- 4371190
TI  - Enucleated neuroblastoma cells form neurites when treated with dibutyryl cyclic
      AMP.

PMID- 4371192
TI  - Accelerated induction to two-kidney hypertension in rats and renin-angiotensin
      sensitivity.

PMID- 4371193
TI  - Mullerian adenosarcoma of the uterus. A clinicopathologic analysis of ten cases
      of a distinctive type of mullerian mixed tumor.

PMID- 4371194
TI  - Restless legs syndrome. Sleep-electroencephalographic and neurologic findings.

PMID- 4371195
TI  - Complete nucleotide sequence of the cohesive ends of bacteriophage P2
      deoxyribonucleic acid.

PMID- 4371197
TI  - [Cyclic GMP and its possible role in cellular regulation].

PMID- 4371196
TI  - Familial hyperlipidemias. Diagnosis and treatment.

PMID- 4371198
TI  - Insulin and growth hormone response to an oral glucose load in Ugandan
      hepatocellular carcinoma patients.

PMID- 4371200
TI  - Alkaline isomerization of ferricytochrome C from Euglena gracilis.

PMID- 4371199
TI  - Insulin reversal of alloxan-diabetes induced changes in gingival collagen
      metabolism of the rat.

PMID- 4371201
TI  - Insulinomas--problems of diagnosis and management.

PMID- 4371202
TI  - Thallium-205 nuclear relaxation and kinetic studies of sodium and potassium ion
      activated adenosine triphosphatase.

PMID- 4371203
TI  - Virologic studies of multiple sclerosis and other chronic and relapsing
      neurological diseases.

PMID- 4371204
TI  - Virologic studies of progressive multifocal leukoencephalopathy.

PMID- 4371206
TI  - Serological survey for antibodies to arboviruses in the human population of
      Portugal.

PMID- 4371205
TI  - Cytological and serological studies of a feline endogenous C-type virus.

PMID- 4371207
TI  - Development of a screening technic to monitor a Mycoplasma-free blu:(LE) Long
      Evans rat colony.

PMID- 4371208
TI  - Development of antibodies to viral and tumor antigens before tumor induction in
      Syrian golden hamsters inoculated intravenously at 3 weeks of age with SV40.

PMID- 4371209
TI  - Development of intranasal vaccination for the immunization of cattle against
      infectious bovine rhinotracheitis.

PMID- 4371210
TI  - Models for metal-protein interaction: copper(II) complexes with some substituted
      cyclic dipeptides.

PMID- 4371212
TI  - [Influence of extracellular calcium and pressure-load on the NADH-dependent
      fluorescence of the frog's ventricle].

PMID- 4371211
TI  - Simultaneous stimulation test for the anterior pituitary hormones.

PMID- 4371214
TI  - [Cellular metabolism of thyroid gland and its regulation].

PMID- 4371215
TI  - Involutional (physiologic) bone loss in women and the feasibility of preventing
      structural failure.

PMID- 4371213
TI  - [Influence of testectomy, estrogen and cyproteronacetate on the enzyme pattern of
      the glandula vesiculosa and the coagulating gland of adult rats (author's
      transl)].

PMID- 4371216
TI  - Involvement of the adrenal gland in ovulation of the fowl.

PMID- 4371217
TI  - [Early and rapid diagnosis for the protection against infections originating from
      the environment].

PMID- 4371218
TI  - Lipolytic activity of adipose tissue. IV. The diacylglycerol lipase activity of
      human adipose tissue.

PMID- 4371219
TI  - Serum lipid and lipoprotein concentrations in a Norwegian population sample.

PMID- 4371220
TI  - Serum lipoproteins and the liver, synthesis and catabolism.

PMID- 4371221
TI  - Serum 17-alpha-hydroxyprogesterone, progesterone, estradiol, and testosterone in
      the diagnosis and management of congenital adrenal hyperplasia.

PMID- 4371222
TI  - Plasma angiotensin II activity in essential hypertension. Relation with vascular
      complications.

PMID- 4371223
TI  - Plasma clotting of female beagle dogs.

PMID- 4371224
TI  - Plasma free fatty acid and triglyceride transport kinetics in man.

PMID- 4371225
TI  - Plasma lipoproteins in patients with familial plasma lecithin: cholesterol
      acyltransferase (LCAT) deficiency--studies on the apolipoprotein composition of
      isolated fractions with identification of LP-X.

PMID- 4371226
TI  - Plasma testosterone during nocturnal sleep in normal men.

PMID- 4371227
TI  - Plasma triglyceride production in man. Effect of noradrenaline infusion.

PMID- 4371228
TI  - Plasma ACTH levels in the human fetus and neonate as related to age and
      parturition.

PMID- 4371229
TI  - Plasma 17-OH-pregnenolone in normal subjects.

PMID- 4371230
TI  - Pharmacokinetic function of the pulmonary circulation.

PMID- 4371231
TI  - Pharmacologic regulation of the early steps of purine biosynthesis in Burkitt
      lymphoma cells and in Ehrlich ascites tumor cells.

PMID- 4371233
TI  - Pharmacological properties of a potential tranquilising agent mesylphenacyrazine.
      II. Changes related to its repeated administration.

PMID- 4371232
TI  - Pharmacological evaluation of a new Ca++ antagonist, 8-(N,N-diethylamino)octyl
      3,4,5-trimethoxybenzoate hydrochloride (TMB-8): studies in skeletal muscles.

PMID- 4371234
TI  - Pharmacological studies with alkylsulfonyloxyalkyl substituted and chloroethyl
      substituted oxazaphosphorine-2-oxides. 1. Communication: relationship between
      chemical structure and pharmacological action.

PMID- 4371235
TI  - Pharmacology of angiotensin.

PMID- 4371236
TI  - [Anomalies of rotation as cause of intestinal obstruction in the new-born
      (author's transl)].

PMID- 4371237
TI  - The management and evaluation of the solitary pulmonary nodule.

PMID- 4371238
TI  - [Primary malignant tumors of the trachea in Israel].

PMID- 4371239
TI  - [Primary retroperitoneal tumors in the adult. Nosologic and diagnostic problems.
      Apropos of 11 new cases].

PMID- 4371240
TI  - Rheumatoid arthritis of the elbow: The results of synovectomy.

PMID- 4371241
TI  - Chromatoid bodies in somatic cells of the planarian: observations on their
      behavior during mitosis.

PMID- 4371242
TI  - Enzyme activities and glycogen concentration in skeletal muscle in alcoholism.
      The effect of abstinence and physical conditioning.

PMID- 4371244
TI  - Enzyme changes during ageing.

PMID- 4371243
TI  - Enzyme and ultrastructural characteristics of esophageal columnar epithelium.

PMID- 4371245
TI  - Cytomegalovirus infection in black children in Durban. A morbid anatomical study.

PMID- 4371246
TI  - The metabolic role of lecithin: cholesterol acyltransferase: perspectives from
      pathology.

PMID- 4371247
TI  - Parameters influencing the purification of calf uterus estrogen 'receptor' by
      affinity chromatography.

PMID- 4371248
TI  - Indomethacin potentiates PGE1 stimulated cyclic AMP accumulation in human
      synoviocytes.

PMID- 4371250
TI  - Dynamic bloodflow studies of space-occupying lesions in the liver.

PMID- 4371249
TI  - Asymmetries in Cu(II) impurity complexes in asparagine monohydrate crystals.

PMID- 4371251
TI  - [Glomic tumor of the ileum with perforation and hemorrhage].

PMID- 4371252
TI  - Vitamin D-resistant rickets and parathyroid adenomas: renal transport of
      phosphate.

PMID- 4371253
TI  - Dopamine and psychotic states: preliminary remarks.

PMID- 4371254
TI  - Thiamine deficiency and oxalosis.
AB  - Type I hyperoxaluria results from reduced activity of alpha-ketoglutarate:
      glyoxylate carboligase, which is necessary for the synergistic decarboxylation of
      glyoxylate and alpha-ketoglutarate to alpha-hydroxy-beta-keto-adipate. Since
      thiamine pyrophosphate is a cofactor in the reaction, thiamine deficiency might
      be expected to result in tissue oxalosis. However, there was no significant
      increase in the incidence of renal oxalosis in 15 patients with Wernicke's
      encephalopathy at necropsy compared with controls. It is possible that
      hyperoxaluria was present in these thiamine-deficient patients but at a urine
      concentration below that necessary for calcium oxalate deposition. It is also
      possible that the severity of the thiamine deficit required for hyperoxaluria
      exceeds that for the neuronal and cardiac manifestations.

PMID- 4371256
TI  - Thermogram and mammogram.

PMID- 4371255
TI  - Dopaminergic nervous transmission in Parkinson's disease.

PMID- 4371258
TI  - Thermoluminescent supralinear response as an optical emission effect for CaF2 Vk
      centers.

PMID- 4371259
TI  - A tumor associated antigen in human nephroblastomas.

PMID- 4371257
TI  - Low molecular weight nuclear RNA. The 3'-terminal sequence of the U2 RNA.

PMID- 4371260
TI  - Pleomorphic salivary adenoma of the lower lip: a rare site of occurrence.

PMID- 4371261
TI  - Chromosomal nonhistone proteins of rat hepatomas and normal rat liver.

PMID- 4371262
TI  - Jaw movements and rumen motility as criteria for measurement of deep sleep in
      cattle.

PMID- 4371263
TI  - A simple direct assay for cyclic AMP in plasma and other biological samples using
      an improved competitive protein binding technique.

PMID- 4371264
TI  - A simple method for density gradient zonal electrophoresis with imidazole-glycine
      buffer and its application to a study of cyclic AMP-binding protein.

PMID- 4371266
TI  - The mutagenic effect of ethylmethanesulfonate on Drosophila melanogaster sperm
      and spermatids.

PMID- 4371265
TI  - A simple method for routine determination of adenylate cyclase activity in intact
      fat cells.

PMID- 4371267
TI  - Human cancer and animal viral oncology.

PMID- 4371268
TI  - Human cancer virus vaccines and the pursuit of the practical.

PMID- 4371269
TI  - Human chromosome 21 dosage: effect on the expression of the interferon induced
      antiviral state.
AB  - Human primary skin fibroblasts trisomic for chromosome 13, 18, or 21 and diploid
      human skin fibroblasts were induced for an antiviral response with human
      interferon. The cells that were trisomnic for chromosome 21 were three to seven
      times more sensitive to protection by human interferon than the normal diploid or
      trisomic 18 or 13 fibroblasts. The differential response in trisomnic 21 cells is
      consistent with the known assignment of the human antiviral gene to chromosome
      21.

PMID- 4371270
TI  - [Iron determination in biological material circumventing phosphate disorders].

PMID- 4371271
TI  - Human hemopexin. Preparation and magnetic properties.

PMID- 4371272
TI  - Human liver nuclear transcortin. Its postulated role in glucocorticoid regulation
      of genetic activity.

PMID- 4371274
TI  - Renin-secreting juxtaglomerular-cell tumour.

PMID- 4371273
TI  - Human IMP dehydrogenase. Kinetics and regulatory properties.

PMID- 4371275
TI  - Renin, angiotensin II and juxtaglomerular apparatus in liver cirrhosis.

PMID- 4371277
TI  - An anaerobic screw-cap culture tube.

PMID- 4371276
TI  - Renin, angiotensin, and aldosterone.

PMID- 4371278
TI  - Coronavirus infection in acute lower respiratory tract disease of infants.

PMID- 4371279
TI  - Absence of action potentials in frog slow muscle fibres paralysed by botulinum
      toxin.
AB  - 1. As shown previously, slow muscle fibres of the frog develop the ability to
      produce action potentials in 2 weeks after denervation.2. Normal transmission at
      the slow fibre neuromuscular junction gives a junction potential of 11 mV average
      (range 6-20 mV), caused by summation of potentials from several motor axons.3.
      Botulinum toxin injected intramuscularly into the iliofibularis blocks the
      neuromuscular junction of slow fibres in 6 days at room temperature. Single nerve
      stimuli give junction potentials of 0.05 mV average (range 0-1.6 mV). Contraction
      of slow fibres in response to tetanic stimulation is eliminated.4. No action
      potentials could be elicited in botulinum treated fibres, even 6(1/2) weeks after
      injection of toxin. This finding is discussed in relation to the possible
      involvement of a ;trophic' factor regulating the action potential mechanism in
      frog slow muscle fibres.

PMID- 4371280
TI  - Enhancement of bee venom phospholipase A2 activity by melittin, direct lytic
      factor from cobra venom and polymyxin B.

PMID- 4371281
TI  - Enhancement of simian virus 40 infection in simian and human cells by permissive
      cell extracts.

PMID- 4371283
TI  - Equine infectious anemia.

PMID- 4371284
TI  - Canine lingual granular cell myoblastoma: a case report.

PMID- 4371282
TI  - Advances in ocular therapy: noncorticosteroid anti-inflammatory agents. Fifth
      annual Jules Stein Lecture.

PMID- 4371285
TI  - Bovine lymphosarcoma (leukemia)-a synopsis.

PMID- 4371286
TI  - Purine nucleotide metabolism in the cat brain after one hour of complete
      ischemia.

PMID- 4371287
TI  - Immune responses to virus induced experimental leukemia and to human leukemia.

PMID- 4371288
TI  - Corynebacterium ulcerans mastitis in a bonnet macaque (Macaca radiata).

PMID- 4371289
TI  - Cutaneous afferent stimulation for relief of chronic pain.

PMID- 4371290
TI  - Cutaneous pseudolymphoma resulting from antigen injections.

PMID- 4371291
TI  - Cutaneous Herpesvirus hominis (type 2) infection after renal transplantation.

PMID- 4371292
TI  - The nephrotic syndrome in the first year of life: is a pathologic classification
      possible?

PMID- 4371293
TI  - On influence of aflatoxin B1 on the physical properties of the avian
      myeloblastosis virus BAI strain A (AMV) and on the biosynthesis of viral nucleic
      acids.

PMID- 4371295
TI  - Laryngeal pleomorphic adenoma.

PMID- 4371294
TI  - Typing Herpesvirus hominis antibodies and isolates by inhibition of the indirect
      hemagglutination reaction.
AB  - Inhibition of the indirect hemagglutination reaction (IHA inhibition) was
      compared to several other methods for type-specific identification of Herpesvirus
      hominis (HVH) antibodies and isolates. The method appears to have the greatest
      value for typing antibodies for HVH type 1 and HVH type 2 in human sera;
      identification of antibody type was relatively simple and results were
      definitive. The IHA-inhibition test permitted serological diagnosis of HVH type 2
      infection in three young adults with meningoencephalitis, thus extending the
      mounting evidence that nervous system involvement with this virus type is not
      limited to neonatal infections. II/I indexes of neutralizing or IHA antibody gave
      an accurate indication of the presence of HVH type 2 antibody in those sera
      containing type 2 antibody by IHA inhibition, but they indicated the presence of
      HVH type 2 antibody in one-half or more of the sera shown to contain only HVH
      type 1 antibody by IHA inhibition. For typing HVH isolates, the IHA-inhibition
      test gave results identical to those obtained by direct fluorescent-antibody
      staining using cross-absorbed conjugates, but the IHA-inhibition test was much
      more cumbersome and time-consuming to perform than was direct fluorescent
      antibody staining. A microneutralization technique for virus typing also gave
      results identical to those obtained with direct fluorescent-antibody staining and
      IHA inhibition. However, typing HVH isolates by plaque size or the differential
      effect of incubation temperature was found to be less definitive and accurate.

PMID- 4371296
TI  - Meningeal reactions seen with myodil myelography.

PMID- 4371297
TI  - [Changes in the rat myocardium caused by diets containing different oils (peanut,
      canbra, colza)].

PMID- 4371298
TI  - An angiotensin converting-enzyme inhibitor to identify and treat vasoconstrictor
      and volume factors in hypertensive patients.

PMID- 4371300
TI  - Chronic destructive polyarthritis due to pyrophosphate crystal arthritis
      ("pseudogout" syndrome).

PMID- 4371301
TI  - Chronic effects of botulinum toxin on neuromuscular transmission and sensitivity
      to acetylcholine in slow and fast skeletal muscle of the mouse.
AB  - 1. A sublethal dose of botulinum toxin (type A) was injected into the muscles of
      one hind limb of the mouse causing local paralysis.2. Neuromuscular transmission
      and muscle sensitivity to acetylcholine (ACh) were studied in vitro in soleus and
      extensor digitorium longus (EDL) from 6 hr to 4 months after the injection of
      toxin.3. Both soleus and EDL failed to respond to nerve stimulation within 6 hr
      of the injection of toxin.4. In muscle fibres in which neuromuscular transmission
      was blocked, subthreshold end-plate potentials (e.p.p.s) were recorded. The
      amplitude of the e.p.p.s increased during recovery from the effects of the toxin
      and both muscles contracted in response to nerve stimulation after 2-3 weeks.5.
      For about 2 months muscles fatigued more rapidly than normal during repetitive
      nerve stimulation because of the low quantal content of e.p.p.s.6.
      Supersensitivity to ACh developed in 3-5 days and persisted after the return of
      neuromuscular transmission. Muscle sensitivity to ACh became normal when the rate
      of fatigue during nerve stimulation was normal.

PMID- 4371302
TI  - [Clinical applications of the study of cellular receptors of steroid hormones].

PMID- 4371303
TI  - [Clinical aspects of arrhenoblastoma ovarii].

PMID- 4371299
TI  - Ammonia formation in brain slices.

PMID- 4371304
TI  - [Clinical characteristics of the main histological forms of liver cancer].

PMID- 4371305
TI  - Subunit structure of the apoprotein of human serum low density lipoproteins.

PMID- 4371306
TI  - Meconium corpuscles in intestinal epithelium of fetal and newborn primates.

PMID- 4371307
TI  - Adrenocorticotropin stimulation of cyclic adenosine 3', 5'-monophosphate
      formation in isolated rat adrenal cells. The role of membrane sialic acid.

PMID- 4371309
TI  - Immunofluorescent demonstration of double-stranded RNA and virus antigen in RNA
      virus-infected cells.

PMID- 4371308
TI  - Melanocyte function: influence of cyclic adenosine monophosphate.

PMID- 4371310
TI  - Immunologic evidence for horizontal transmission of MTV.

PMID- 4371311
TI  - Immunological destruction of herpes simplex virus I infected cells.

PMID- 4371312
TI  - Immunological intervention in neoplasia.

PMID- 4371313
TI  - An anomaly of the genetic regulation of the de novo pyrimidine pathway in the
      plant Arabidopsis.

PMID- 4371315
TI  - Immunotherapy of guinea pig cancer with BCG.

PMID- 4371314
TI  - Diagnosis of salivary gland tumors.

PMID- 4371316
TI  - Toxins and enzymes of coagulase negative staphylococci isolated from human
      infections.

PMID- 4371317
TI  - A sensitive method for the separation and quantitation of (14C)proline and
      (14C)hydroxyproline from the collagen of rat uterus.

PMID- 4371319
TI  - Demonstration of an enhanced alpha-adrenergic response in human adipose tissue
      when incubated in presence of Li+ instead of Na+.

PMID- 4371318
TI  - Reconstituted liver microsomal enzyme system that hydroxylates drugs, other
      foreign compounds and endogenous substrates. VII. Stimulation of benzphetamine N
      demethylation by lipid and detergent.

PMID- 4371320
TI  - Demonstration of collagenase activity in rat liver homogenate.

PMID- 4371321
TI  - Demonstration of low-titer anti-Pr cold agglutinins.

PMID- 4371322
TI  - Demonstration of the in vivo action of pepstatin: effects on plasma angiotensin
      II concentration.

PMID- 4371323
TI  - Potential generation in bilayer lipid membranes in the NADH-flavin mononucleotide
      ubiquinone-6-O2 system.

PMID- 4371324
TI  - Potential X-ray contrast agents. 3. Synthesis of some derivatives of
      iodomethanesulphonic acid and tris-iodomethylacetic acid.

PMID- 4371325
TI  - [Identification of corticotropic cells in the sturgeon hypophysis and hypophyseal
      interrenal interrelations in these fishes].

PMID- 4371326
TI  - Infantile type of so-called neuronal ceroid-lipofuscinosis.

PMID- 4371327
TI  - Attention in the cat: electrophysiological and behavioural studies.

PMID- 4371328
TI  - An ontogenic study on the effect of catecholamine receptor-stimulating agents on
      the turnover of noradrenaline and dopamine in the brain.

PMID- 4371329
TI  - Mutants of the N-3 R-factor conditionally defective in hspII modification and
      deoxyribonucleic acid-cytosine methylase activity.
AB  - The N-3 drug resistance (R) factor specifies a deoxyribonucleic acid (DNA)
      cytosine methylase and a DNA restriction-modification (hspII) system. We have
      isolated three independent mutants that are conditionally defective in their
      ability to modify bacteriophage lambda and to methylate DNA-cytosine residues.
      The ratio of 5-methylcytosine to N(6)-methyladenine in bacterial DNA and in the
      DNA of phages lambda and fd was determined after labeling with [methyl
      (3)H]methionine at various growth temperatures. Although the ability of the wild
      type N-3 factor to modify phage lambda and to methylate DNA-cytosine residues was
      unaffected with increasing temperature, two of the mutants exhibited a parallel
      loss in modification and cytosine methylation ability. The ability of the third
      mutant to carry out these functions was dependent on the presence or absence of
      an amber suppressor mutation in the host genome. These results offer further
      support for the notion that hspII modification is mediated by a DNA-cytosine
      methylase. Evidence is also presented that the modification methylase is
      responsible for the in vivo methylation of phage fd DNA (which is not subject to
      hspII restriction in vivo).

PMID- 4371331
TI  - Ice nucleation induced by pseudomonas syringae.
AB  - Broth cultures of suspensions of Pseudomonas syringae isolated from decaying
      alder leaves (Alnus tenuifolia) were found to freeze at very warm (-1.8 to -3.8
      C) temperatures. The initiation of freezing appears associated with the intact
      cell and not with extracellular material. Chemical treatments and physical
      destruction of the cell destroy activity. Bacteria must be in concentrations of
      approximately 10(6)/ml before freezing at warm temperatures occurs.

PMID- 4371330
TI  - Ribonuclease H activities associated with Herpes simplex virus.

PMID- 4371332
TI  - The nucleotide sequence of 5 S rRNA from the blue-green alga Anacystis nidulans.

PMID- 4371334
TI  - [Malnutrition at an early age--changes of the nervous system].

PMID- 4371333
TI  - An unusual karyotypic observation on cultured cells from an owl monkey (Aotus
      trivirgatus).
AB  - A cell line, established from a pathological lymph node of an owl monkey, Aotus
      trivirgatus s.sp. trivirgatus, was found to have two cell populations
      distinguished from one another by chromosome number. The normal karyotype was
      present in the population of cells with 54 chromosomes; the other cell
      population, with 55 chromosomes, possessed a normal karyotype but with one
      additional abnormal chromosome. The significance of this extra chromosome is
      discussed.

PMID- 4371335
TI  - [Adenylate cyclase and cyclic 3',5'-AMP content in isolated retinal outer
      segments].

PMID- 4371336
TI  - Amino acid transport and staphylococcal membrane vesicles.

PMID- 4371337
TI  - Microbial penicillin acylases.

PMID- 4371338
TI  - Protocatechuate 3, 4-dioxygenase. Cobalt substitution for iron.

PMID- 4371339
TI  - Histochemical data on the sebaceous glands in the lips of the marmoset
      (Callithrix jacchus).

PMID- 4371340
TI  - Histochemical localization of phosphohydrolases in testes of man and rat.

PMID- 4371343
TI  - [Myxochondroepithelioma in stomatological practice].

PMID- 4371342
TI  - Histochemical studies of hydropic degeneration of the rat liver induced by carbon
      disulphide.

PMID- 4371341
TI  - Histochemical observations on the human foetal testis with reference to steroid
      hormone synthesis.

PMID- 4371344
TI  - [Association of ectodermal dysplasia, ectrodactyly and cleft lip-palate: the EEC
      syndrome].

PMID- 4371345
TI  - Dissociation of growth hormone and prolactin secretion in Parkinson's disease
      following chronic L-dopa therapy.

PMID- 4371346
TI  - Dissociation properties of aspartokinase I-homoserine dehydrogenase I extracted
      from a missense mutant of E. coli K12.

PMID- 4371347
TI  - Histocompatibility studies on the husband-wife pair with trophoblastic neoplasia.

PMID- 4371348
TI  - Glucocorticoid binding in the chicken liver cytosol.

PMID- 4371349
TI  - Glucocorticoids and hCG sensitivity of rat testicular Leydig cell.

PMID- 4371350
TI  - [Endocrinological studies on myotonic dystrophy--insulin and HGH responses in
      myotonic dystrophy].

PMID- 4371351
TI  - [Endocrinology in pregnancy].

PMID- 4371352
TI  - Chemodectomas.

PMID- 4371353
TI  - [Cytodiagnosis of lung carcinoma as based on the records of in-patients of the
      tuberculosis and respiratory diseases hospitals in Wroclaw, Oborniki Slaskie and
      Kowary].

PMID- 4371354
TI  - Methods for preparation of secretory granules from anterior pituitary glands.

PMID- 4371355
TI  - Introduction of a cross-infection rate in children's wards and its application to
      respiratory virus infections.
AB  - Statistical methods are described in detail for the calculating and comparing of
      cross-infection rates. In addition the use of these rates has been extended to
      study the influence of age and of different virus types on susceptibility to
      cross-infection in children's wards.

PMID- 4371356
TI  - Introduction to virus-caused cancer: type C virus.

PMID- 4371357
TI  - Use of streptomycin and cyclic adenosine 5'-monophosphate in the isolation of
      mutants deficient in CAP protein.
AB  - A method is described for selective isolation of mutants deficient in CAP protein
      necessary for the expression of catabolite-sensitive operons in Escherichia coli.

PMID- 4371358
TI  - Neurofibromatosis (Recklinghausen's disease) with gastrointestinal and uterine
      manifestations: report of a case.

PMID- 4371359
TI  - Neurogenic and humoral factors controlling vascular resistance in the
      spontaneously hypertensive rat.

PMID- 4371360
TI  - Onocogenic conversion of normal cells by inactivated herpes simplex viruses.

PMID- 4371362
TI  - Pathogenicity of five Asian strains of Entamoeba histolytica in laboratory rats.

PMID- 4371361
TI  - Pathogenic role of cyclic AMP in the impairment of urinary concentrating ability
      in acute hypercalcemia.
AB  - A possible association between the impairment of urinary concentrating ability
      and an impairment of the vasopressin-dependent cyclic AMP system in hypercalcemia
      was investigated in rat kidneys both in vivo and in vitro. The increases of
      urinary osmolality and negative free water clearance and the increase of urinary
      cyclic AMP excretion by vasopressin injection were significantly less in the
      hypercalcemic rats than in the control rats. The increase of cyclic AMP
      concentration by vasopressin in renal medullary tissue was significantly less in
      the slices obtained from the hypercalcem'c rats than in those obtained from the
      control rats. The activation of adenylate cyclase by vasopressin was
      significantly less in the group with an increased concentration of calcium in
      media than the control group, but phosphodiesterase activity was not affected by
      calcium concentration in the media. These data suggest that the impaired urinary
      concentrating ability in hypercalcemic kidneys is due at least in part to the
      direct inhibitory effect of calcium on the vasopressin-dependent cyclic AMP
      system at the level of adenylate cyclase in renal medulla.

PMID- 4371364
TI  - Amniography for the detection of fetal myelomeningocele.

PMID- 4371363
TI  - Biological properties of extracellular proteins from staphylococcus.

PMID- 4371365
TI  - Angiography in radiation "hepatitis".

PMID- 4371366
TI  - Neurohypophyseal hormones and analogues: rat pressor potency versus contractile
      potency on rat arterioles and arteries.

PMID- 4371367
TI  - Steroid binding in polyacrylamide gels. Quantitation at steady state conditions.

PMID- 4371369
TI  - Steroid production by the isolated rabbit ovarian follicle. II. Effects of
      peptide hormones.

PMID- 4371368
TI  - Adenoid cystic carcinoma of salivary origin. A clinicopathologic study of 242
      cases.

PMID- 4371370
TI  - Steroids, hypertension, and fluid retention in the genesis of postoperative
      seizures with inflammatory bowel disease in childhood.

PMID- 4371371
TI  - Sterol compositions of echinoids (sea urchin, sand dollar and heart urchin).

PMID- 4371372
TI  - [Iodolipol as a foreign body in the maxillary sinus].

PMID- 4371373
TI  - [Auxological data on infantile bronchial asthma].

PMID- 4371374
TI  - [Cytological diagnosis of skin cancer].

PMID- 4371375
TI  - [Cytological examination of sputum in lung carcinoma].

PMID- 4371376
TI  - Radiological examination of the stomach with a potentiated double contrast
      technique.

PMID- 4371377
TI  - Radiological follow-up examination of the mineral salt content in the various
      vitamin D-resistant forms of rachitis of renal origin.

PMID- 4371378
TI  - [Serological studies of respiratory diseases in calves in relation to Myxovirus
      parainfluenzae-3, adenoviruses and Neorickettsia].

PMID- 4371379
TI  - Histologically different, synchronous, bilateral carcinoma of the male breast (a
      case report).

PMID- 4371380
TI  - Aetiology and epidemiology of viral croup in Glasgow, 1966-72.
AB  - A retrospective study of 258 children admitted to Ruchill Hospital, Glasgow, with
      croup between 1966 and 1972 indicated that the viruses most frequently associated
      with the syndrome were parainfluenza types 1 and 3 and influenza A. Most cases
      were admitted in the late autumn and winter months, with a small peak in May and
      June. This seasonal distribution mirrored the circulation of the main causative
      agents in the community, parainfluenza 1 being principally associated with the
      autumn cases, influenza A the winter cases and parainfluenza 3 the summer cases.
      Two of these ;croup associated' viruses showed regular periodicity, parainfluenza
      1 occurring biennially in even years and influenza A in most years. The
      periodicity of parainfluenza 3 is as yet undetermined.

PMID- 4371381
TI  - Pathology and pathogenesis of the common diseases of the respiratory tract of
      cattle.

PMID- 4371382
TI  - Glycolysis in the digestive gland of healthy and parasitized Littorina saxatilis
      rudis (Maton) and in the daughter sporocysts of Microphallus similis (Jag.)
      (Digenea: Microphallidae).

PMID- 4371383
TI  - Radiolysis of biochemical systems using adamantane as an isolation matrix.

PMID- 4371384
TI  - Sarcoma and transformation-defective viruses produced with infectious DNA(s) from
      Rous sarcoma virus (RSV)-transformed chicken cells.

PMID- 4371385
TI  - Thecoma with extensive calcification.

PMID- 4371386
TI  - Thymoma with systemic lupus erythematosus, red blood cell aplasia, and
      herpesvirus infection.

PMID- 4371387
TI  - [Chromatography of steroids in a thin layer of silufol impregnated with
      phosphomolybdic acid (author's transl)].

PMID- 4371388
TI  - [Cytomegalic inclusion disease of parotid and submandibular glands in an infant].

PMID- 4371389
TI  - [A comparison of positive and negative contrast media for the demonstration of
      the third and fourth ventricles (author's transl)].

PMID- 4371390
TI  - Poliomyelitis in the German Federal Republic. Sporadic diseases by imported wild
      poliovirus.

PMID- 4371391
TI  - Carbon dioxide laser in head and neck surgery.

PMID- 4371392
TI  - Fusion of chicken erythrocytes by phospholipase C (Clostridium perfringens). The
      requirement for hemolytic and hydrolytic factors for fusion.

PMID- 4371394
TI  - Action of metabolic hormones on the fine structure of rat liver cells. III.
      Effects of adrenalectomy and administration of cortisone.

PMID- 4371393
TI  - Fusion of intact human erythrocytes and erythrocyte ghosts.
AB  - Sendai virus is able to induce the fusion of human erythrocytes. Bivalent cations
      or ATP are not essential for polyerythrocyte formation. High fusion indices were
      obtained when Sendai virus was added to cells incubated in the presence of both
      EDTA and iodoacetic acid. Human erythrocyte ghosts prepared by gradual hemolysis
      still retain the potential to undergo virus-induced fusion. Fusion of human red
      blood cells without the addition of viruses was obtained by incubation of
      erythrocytes at pH 10.5 in the presence of Ca(++) (40 mM) or by addition of
      phospholipase C Clostridium perfringens preparations to cells previously
      agglutinated or polylysine.

PMID- 4371395
TI  - Action of thyrotropin on phosphate incorporation into thyroid proteins in vitro.

PMID- 4371396
TI  - Proton relaxation studies of diphosphopyridine coenzymes.

PMID- 4371398
TI  - Hormonal control of the potassium level in isolated rat liver cells.

PMID- 4371397
TI  - Rational basis for an immunization program against the common diseases of the
      bovine respiratory tract.

PMID- 4371400
TI  - Hormonal regulation of amino acid accumulation in human fetal liver explants.
      Effects of dibutyryl cyclic AMP, glucogon and insulin.

PMID- 4371401
TI  - Neuronal storage disorder with chorea and curvilinear bodies.

PMID- 4371402
TI  - [Coronary disease and the "accessory" pre-beta band: a causal relationship?].

PMID- 4371399
TI  - Hormonal effects of synthetic ACTH analogues.

PMID- 4371403
TI  - [Hyponatremic coma, first symptom of oat-cell carcinoma of the lung].

PMID- 4371404
TI  - Hormone synthesis and release from human fetal adenohypophyses in vitro.

PMID- 4371406
TI  - Actions of excitatory amino acids and their antagonism.

PMID- 4371405
TI  - Components of the renin-angiotensin system in the rat during development.

PMID- 4371407
TI  - Prisons, adolescents, and the right to quality medical care: the time is now.

PMID- 4371409
TI  - Response to LH-RH in women before and after treatment with prednisone.

PMID- 4371408
TI  - Response of isolated human ventricular myocardium to cyclic AMP and its dibutyryl
      derivative.

PMID- 4371410
TI  - Responses of antidromically identified preoptic neurons in the rat to
      neurotransmitters and to estrogen.

PMID- 4371412
TI  - [Demonstration of a specific receptor of testosterone in the cytoplasm of the
      anterior pituitary of the prepuberal male rat].

PMID- 4371411
TI  - Responses of guinea pig umbilical vasculature to vasoactive drugs.

PMID- 4371413
TI  - [Demonstration of the IBR-IPV virus in the vaginal secretion of cows with
      vulvovaginitis].

PMID- 4371414
TI  - [Cytopathic effect of Aujeszky's virus on cell cultures].

PMID- 4371415
TI  - [Idiopathic trigeminal neuropathy].

PMID- 4371416
TI  - Cyclopenta(f)isoquinoline derivatives designed to bind specifically to native
      deoxyribonucleic acid. 3. Interaction of 6-carbamylmethyl-8-methyl-7H
      cyclopenta(f)isoquinolin-3(2H)-one with deoxyribonucleic acids and
      polydeoxyribonucleotides.

PMID- 4371417
TI  - Macrophage spreading in vitro. III. The effect of metabolic inhibitors,
      anesthetics and other drugs on spreading induced by subtilisin.

PMID- 4371418
TI  - [Oesophagitis in Stevens-Johnson syndrome (author's transl)].

PMID- 4371419
TI  - Hydrophobic interaction of human interferon with concanavalin A-agarose.

PMID- 4371420
TI  - Netropsin. A specific probe for A-T regions of duplex deoxyribonucleic acid.

PMID- 4371421
TI  - Radioreceptor and radioimmunoassay quantitation of human growth hormone in
      acromegalic serum: overestimation by immunoassay and systematic differences
      between antisera.

PMID- 4371422
TI  - Radioreceptor assay for somatomedin A.

PMID- 4371424
TI  - Editorial: Cytomegalovirus again.

PMID- 4371423
TI  - Editorial: Angiotensin inhibition.

PMID- 4371425
TI  - Editorial: Diffuse interstitial pulmonary calcification.

PMID- 4371426
TI  - Editorial: Some newer endocrine aspects of breast cancer.

PMID- 4371427
TI  - Performance and concentration of airway washings of chickens.

PMID- 4371429
TI  - Conformational changes induced in Escherichia coli ribosomes by streptomycin. A
      spin label study.

PMID- 4371428
TI  - Conformational change associated with the acylation of alpha-chymotrypsin by N
      acetyl-L-phenylalanine methyl ester.

PMID- 4371430
TI  - Conformational mobility of the pyrrolidine ring of proline in peptides and
      peptide hormones as manifest in carbon 13 spin-lattice relaxation times.

PMID- 4371431
TI  - Factors influencing pituitary glycogen metabolism and gonadotropic hormone
      release. I. Luteinizing hormone-releasing hormone.

PMID- 4371432
TI  - Factors influencing pituitary glycogen metabolism and gonadotropic hormone
      release. II. A role of prostaglandins.

PMID- 4371433
TI  - Osteosclerotic myeloma with peripheral neuropathy.

PMID- 4371434
TI  - Adenosine 3',5'-cyclic monophosphate-deficient mutants of Vibrio cholerae.
AB  - Two adenosine 3',5'-cyclic monophosphate (AMP)-deficient mutants of Vibrio
      cholerae (biotype El Tor) were successfully isolated by nitrosoguanidine
      treatment followed by pencillin screening for pleiotropic sugar-negative clones.
      Exogenous cyclic AMP is required for the fermentation of sucrose, trehalose,
      fructose, maltose, and mannose but not of glucose, as well as for the formation
      of normal flagella and specific somatic antigens. A striking characteristic of
      the mutants is their growth behavior at higher temperatures. They cannot grow on
      TCBS selective plates at 37 C or higher unless they are provided with a supply of
      exogenous cyclic AMP, although they are capable of producing colonies on the same
      medium, even without cyclic AMP, at temperatures lower than 30 C. Since the
      mutants are converted to spheroplasts, spindle forms, and spiral filaments in
      cyclic AMP-free media at 37 C, and this phenomenon is stopped by the addition of
      cyclic AMP or a combination of 20% sucrose and 0.2% magnesium chloride, it is
      assumed that cyclic AMP is essential for the synthesis of the cell wall of V.
      cholerae at higher temperatures.

PMID- 4371435
TI  - Adenosine 3':5'-monophosphate-dependent protein kinase-catalyzed phosphorylation
      reaction and its relationship to calcium transport in cardiac sarcoplasmic
      reticulum.

PMID- 4371436
TI  - Adenosine 5'-triphosphate release and membrane collapse in glycerol-requiring
      mutants of Bacillus subtilis.
AB  - Glycerol-requiring mutants of Bacillus subtilis could not sporulate in nutrient
      sporulation medium even when additional glycerol was added from the beginning of
      growth. Sporulation could be partially restored either by the frequent addition
      of small amounts of glycerol during the developmental period or by the single
      addition of both 10 mM glycerol and 10 mM malate. But sporulation could be
      completely restored by the addition of 50 mM glycerol-phosphate from the
      beginning. At the end of growth of the glycerol mutants in nutrient sporulation
      medium, the cell membrane collapsed and separated from the cell wall, and much of
      the cellular adenosine 5'-triphosphate was released into the medium. These
      observations were made in two glycerol mutants, one derived from strain 168
      containing glycerol-teichoic acid in the cell wall and the other derived from
      strain W23 containing ribitol-teichoic acid.

PMID- 4371438
TI  - [Exposure to lead in the general environment and in places of employment. II.
      Physiopathological and clinical aspects].

PMID- 4371437
TI  - Phytosterols.

PMID- 4371439
TI  - Glycosyl glycerides.

PMID- 4371440
TI  - Mannosyltransferase activity in calf pancreas microsomes. Formation from
      guanosine diphosphate-D-(14C)mannose of a 14C-labeled mannolipid with properties
      of dolichyl mannopyranosyl phosphate.

PMID- 4371442
TI  - Hypnotic suggestions for learning during stage I REM sleep.

PMID- 4371441
TI  - A protein-bound form of porcine renal renin.

PMID- 4371444
TI  - Pronounced antiviral activity of human interferon on bovine and porcine cells.

PMID- 4371443
TI  - Enzootic Brucella canis--an occult disease in a research canine colony.

PMID- 4371445
TI  - An "outbreak" of juvenile diabetes mellitus: consideration of a viral etiology.

PMID- 4371446
TI  - Improved methods for the study of drug effects on purine metabolism and their
      application to nebularine and 7-deazanebularine.

PMID- 4371447
TI  - The oxidation state of copper in resting tyrosinase.

PMID- 4371448
TI  - Hydroxylysine glycosides in the collagen of normal and scarred rabbit corneas.

PMID- 4371449
TI  - Sleep deprivation in cattle.

PMID- 4371450
TI  - Sleep in hypnosis: a pilot EEG study.

PMID- 4371452
TI  - [Comparative localization of anti-lipotropin, anti-corticotropin and anti-beta
      melanotropin immune serums at the level of the pituitary gland in swine].

PMID- 4371451
TI  - [Comparative investigation on sputum viscosity before and after administration of
      mistabron or physiological saline solution with and without physiotherapy
      (vibration-therapy) (author's transl)].

PMID- 4371453
TI  - [Comparative testing of saponified vaccines against Aujeszky's disease].

PMID- 4371454
TI  - Idiopathic sexual precocity in a boy with growth hormone, prolactin and
      thyrotropin deficiencies.

PMID- 4371455
TI  - The pathogenesis of hexachlorophene neuropathy: in vivo and in vitro studies.

PMID- 4371456
TI  - C-type viral particles in a urinary bladder neoplasm induced by Schistosoma
      haematobium.

PMID- 4371457
TI  - Independence of cholesterol and fatty acid biosynthesis from cyclic adenosine
      monophosphate concentration in the perfused rat liver.

PMID- 4371458
TI  - Independent dibutyryl cyclic adenosine monophosphate stimulation of human
      chorionic gonadotropin and estrogen secretion by malignant trophoblast cells in
      vitro.

PMID- 4371459
TI  - Subependymal veins and ventricular tumors.

PMID- 4371460
TI  - Polypeptide composition of urea- and heat-resistant mutants of poliovirus types 1
      and 2.
AB  - Five urea-resistant and two heat-resistant mutants of poliovirus types 1 and 2
      were isolated and their structural and nonstructural polypeptides compared to
      those of their wild-type, parental strains in an attempt to correlate mutant
      phenotypes with alterations in specific capsid polypeptides. Four of the seven
      mutants were found to contain polypeptides which differed in molecular weight
      from their respective parental viruses. However, resistance of virions to heat-
      or urea-inactivation could not be attributed to changes in particular capsid
      polypeptides because alterations were detected in all but one of the capsid
      components. For two of the urea-resistant mutants and one heat-resistant mutant,
      no differences were found in the molecular weights of the capsid and noncapsid
      polypeptides. These results, and the fact that at least 12 selective treatments
      were required to obtain stable mutants, indicate that: (i) such phenotypes
      probably can be expressed by mutations affecting one or more of the larger capsid
      polypeptides, and (ii) such phenotypes reflect multiple mutational steps.

PMID- 4371461
TI  - Polypeptides of Moloney sarcoma-leukemia virions: their resolution and
      incorporation into extracellular virions.

PMID- 4371462
TI  - The peribrachial region of cat. II. Distribution of acetylthiocholinesterase and
      monoaminoxidase, with special reference to the locus coeruleus.

PMID- 4371463
TI  - [Properties of lecithin monolayers from tumors and homologous normal tissues at
      the water-air interface].

PMID- 4371464
TI  - [Competition between estradiol and various progestogens at the level of the rat
      hypothalamus].

PMID- 4371465
TI  - Phosphate metabolism in blue-green algae. I. Fine structure of the "polyphosphate
      overplus" phenomenon in Plectonema boryanum.

PMID- 4371466
TI  - [Lymphographic findings in carcinoma of the prostate (author's transl)].

PMID- 4371467
TI  - [Lymphography for malignant melanoma (author's transl)].

PMID- 4371468
TI  - Phospholipid exchange between membranes. Purification of bovine brain proteins
      that preferentially catalyze the transfer of phosphatidylinositol.

PMID- 4371470
TI  - Phosphorylation of proteins of ribosomes and nucleolar preribosomal particles in
      vivo in Novikoff hepatoma ascites cells.

PMID- 4371469
TI  - [Morphological and biochemical lesions of the rat liver in trichlorobromomethane
      poisoning].

PMID- 4371471
TI  - Ectopic fetal adrenal cortex in the lung of a newborn.

PMID- 4371473
TI  - A rapid, simple and reliable method for the screening of potential antiviral
      compounds in vitro.

PMID- 4371472
TI  - A rapid micromethod for the determination of nitrogen and phosphate in biological
      material.

PMID- 4371474
TI  - Incipient pulmonary emphysema. II. Genetics and biochemistry.

PMID- 4371475
TI  - Cytoplasmic alterations of hepatocytes in rainbow trout (Salmo gairdneri) induced
      by cyclopropenoid fatty acids.

PMID- 4371476
TI  - The preparation and characterisation of a water-soluble coenzymically active
      dextran-NAD+.

PMID- 4371477
TI  - The presence of bound cyanide in the naturally inactivated form of nitrate
      reductase of Chlorella vulgaris.

PMID- 4371478
TI  - The presence of 4-selenouridine in Escherichia coli tRNA.

PMID- 4371479
TI  - Derepression of nitrogenase in Azotobacter.

PMID- 4371480
TI  - The process of establishing a collaborative program between a mental health
      center and a public health nursing division: a case study.

PMID- 4371481
TI  - The properties of water in biological systems.

PMID- 4371482
TI  - Lipoprotein-polyanion-metal interactions.

PMID- 4371483
TI  - The purine DNA base cation and anion radicals: an e.s.r. study.

PMID- 4371484
TI  - The pyrophosphate exchange reaction of histidyl-tRNA synthetase from Salmonella
      typhimurium: reaction parameters and inhibition by transfer ribonucleic acid.

PMID- 4371485
TI  - Water balance and kidney function in some rodents native to Australia.

PMID- 4371486
TI  - Newer insights into the role and modifications of olfaction in man through
      clinical studies.

PMID- 4371487
TI  - 165Er: an "ideal" radionuclide for imaging with pressurized multiwire
      proportional gamma cameras.

PMID- 4371488
TI  - Interaction between adrenergic and cholinergic systems: presynaptic inhibitory
      effect of noradrenaline on acetylcholine release.

PMID- 4371489
TI  - Interaction of estradiol and ACTH in the regulation of adrenal corticosterone
      production in the rat.

PMID- 4371492
TI  - Accuracy of radionuclide cerebral angiograms in the detection of cerebral
      arteriovenous malformations.

PMID- 4371490
TI  - Interaction of staphylococcal protein A with virus-IgG complexes.

PMID- 4371493
TI  - The radiological diagnosis of congenital multicystic kidney 'Radiological Triad'.

PMID- 4371494
TI  - [Intraduodenal diverticulum (case report)].

PMID- 4371495
TI  - [Ultrahistochemical detection of phosphatases and peroxidases in cells of the
      thoracic duct (D. th)].

PMID- 4371496
TI  - A viral inhibitory substance in culture filtrates of Proteus mirabilis. 1.
      Inhibition of Sindbis virus plaque formation without a parallel antiviral action
      in fluid medium.

PMID- 4371497
TI  - Lateral phase separations in binary lipid mixtures: correlation between spin
      label and freeze-fracture electron microscopic studies.

PMID- 4371498
TI  - Programming of events in Epstein-Barr virus-activated cells induced by 5
      iododeoxyuridine.

PMID- 4371500
TI  - Membrane proteins of MSV-MLV: their role in virion-virion interactions in vitro.

PMID- 4371501
TI  - [Ultrastructural study of amyloid neuropathy with special reference to changes of
      the peripheral nerves in asymptomatic siblings].

PMID- 4371499
TI  - Membrane fusion. Transfer of phospholipid molecules between phospholipid bilayer
      membranes.

PMID- 4371502
TI  - [Ultrastructural study of keratinization in the sebaceous cyst (author's
      transl)].

PMID- 4371503
TI  - [Ultrastructural study of mixed metatypic epithelioma (basosquamous
      epithelioma)].

PMID- 4371505
TI  - [Ultrastructure of the kidney in spontaneously diabetic KK mice].

PMID- 4371504
TI  - [Ultrastructure of the corticotrophic cells of the pituitary gland in rat
      following administration of steroidogenesis-inhibitors and methylprednisolone
      (author's transl)].

PMID- 4371506
TI  - Separation of the two non-identical subunits of lombricine kinase from Lumbricus
      terrestris muscle by chromatography on sepharose-mercurial. Isolation of the
      tryptic peptide containing its essential thiol group.

PMID- 4371508
TI  - Alterations of surface properties of chick embryo fibroblasts infected with four
      Rous sarcoma viruses producing distinctive cell transformation.

PMID- 4371507
TI  - Alterations of murine immunologic responses after silica dust inhalation.

PMID- 4371509
TI  - Tuberculin testing in Macaca species: evaluation of two tuberculin diluents.

PMID- 4371510
TI  - Disordered calcium metabolism during anticonvulsant treatment.

PMID- 4371511
TI  - The reaction of alkylating agents with cyclic 3',5'-nucleotide phosphodiesterase.

PMID- 4371512
TI  - Pancreatic islet cell carcinoma metastatic to the eyes.

PMID- 4371513
TI  - Indirect hemagglutinating antibody response to Herpesvirus hominis types 1 and 2
      in immunized laboratory animals and in natural infections of man.
AB  - Indirect hemagglutinating (IHA) antibody responses to Herpesvirus hominis types 1
      and 2 (HVH-1 and HVH-2) were compared to complement-fixing and neutralizing
      antibody responses in immunized laboratory animals (rabbits, guinea pigs, and
      hamsters) and in natural infections of man. With the immunized animals, type
      specificity was seen only in the IHA test and only with antisera produced in
      hamsters and in the rabbits immunized with HVH-2. In human nongenital infections
      (considered to be caused predominately by HVH-1), IHA and neutralizing antibodies
      developed at about the same rate and reached approximately the same levels for
      HVH-1 and HVH-2. IHA titers tended to be higher than neutralizing antibody titers
      for both virus types. In genital infections (considered to be caused
      predominately by HVH-2), there was a rapid IHA antibody response to HVH-2, and
      the early HVH-2 antibody demonstrable by IHA, but not by neutralization tests,
      was found to be immunoglobulin M in nature. In genital infections, IHA titers for
      HVH-2 were markedly higher than neutralization titers, but there was no
      pronounced difference in neutralizing the IHA antibody titers for HVH-1. Several
      patients with genital infections fialed to develop IHA antibody for HVH-1. The
      IHA test possessed no greater sensitivity than did complement fixation or
      neutralization tests for serodiagnosis of HVH infections. Despite the fact that a
      number of patients with genital infections produced IHA antibody only for HVH-2,
      the test was no more effective than the neutralization test in providing a type
      specific serodiagnosis of infection, due largely to the fact that the rapid IHA
      antibody response to HVH-2 prevented demonstration of a further, significant
      antibody titer increase in a number of cases.

PMID- 4371514
TI  - Altered amphibian cell morphology following treatment with polyene antibiotic and
      a mammalian RNA virus.

PMID- 4371515
TI  - Altered protein metabolism in infection by the late tsB11 mutant of simian virus
      40.
AB  - The DNA of the temperature-sensitive mutant tsB11 is replicated at the same rate
      as the DNA of wild-type virus in infection at the restrictive temperature. The
      progeny mutant DNA cannot be distinguished from wild-type DNA by gel
      electrophoresis and is assembled into a nucleoprotein complex with the same
      velocity sedimentation characteristics as the wild-type complex. Analysis of in
      vivo protein synthesis by sodium dodecyl sulfate polyacrylamide gel
      electrophoresis and immunoprecipitation techniques demonstrated that the capsid
      components VP1, VP2, and VP3 of the mutant and wild-type virus are synthesized at
      a similar rate, but VP1 fails to accumulate within cells infected by tsB11.
      Furthermore, VP1 is located predominantly in the cytoplasmic rather than in the
      nuclear fraction of extracts from cells infected by the mutant. Immunofluorescent
      studies localized virion antigen within the nucleolus as well as the cytoplasm.
      The altered intracellular distribution and stability of VP1 suggest that it may
      be the mutant protein of tsB11. The synthesis of a 72,000 dalton protein is
      consistently induced in significant quantity in cells infected by tsB11 at the
      restrictive temperature. A protein of the same apparent molecular weight is
      present in smaller quantities in uninfected cells and is only slightly increased
      in quantity in cells infected by wild-type virus.

PMID- 4371516
TI  - The regulation of cyclic guanosine monophosphate in rat cerebellum: possible
      involvement of putative amino acid neurotransmitters.

PMID- 4371518
TI  - The relationship between plasma and tissue lipids in human atherosclerosis.

PMID- 4371517
TI  - Age-related changes in vascular responsiveness to cyclic nucleotides and
      contractile agonists.

PMID- 4371520
TI  - Low renin, "normal" aldosterone and hypertension: circadian rhythm of renin,
      aldosterone, cortisol and growth hormone.

PMID- 4371521
TI  - Apparent correlation between adenosine 3':5' cyclic monophosphate levels and
      malignancy in somatic cell hybrids.

PMID- 4371519
TI  - The relationship of total dust, free silica, and trace metal concentrations to
      the occupational respiratory disease of bituminous coal miners.

PMID- 4371522
TI  - [Current views on vitamin C metabolism].

PMID- 4371523
TI  - The reovirus murine models.

PMID- 4371525
TI  - The requirement for lipid fluidity in the formation and structure of
      lipoproteins: thermotropic analysis of apolipoprotein-alanine binding to
      dimyristoyl phosphatidylcholine.

PMID- 4371524
TI  - The replication of papovavirus DNA.

PMID- 4371526
TI  - Fluorescent antibody study of a new bovine herpesvirus (strain DN-599).

PMID- 4371527
TI  - Cigarette smoking and cholesterol atherosclerosis of rabbits.

PMID- 4371528
TI  - Interferon inducers in therapy of infection with encephalomyocarditis virus in
      mice. I. Effect of single doses of polyriboinosinic-polyribocytidylic acid and
      tilorone hydrochloride on viral pathogenesis.

PMID- 4371529
TI  - Interferon inducers in therapy of infection with encephalomyocarditis virus in
      mice. II. Effect of multiple doses of polyriboinosinic-polyribocytidylic acid on
      viral pathogenesis.

PMID- 4371530
TI  - Interferon-mediated increased lysis of L-cells by vesicular stomatitis virus.

PMID- 4371531
TI  - Allergy involving the cranial nerves.

PMID- 4371532
TI  - Synergy of 9-beta-D-arabinofuranosyladenine and human interferon against Herpes
      simplex virus, type 1.

PMID- 4371533
TI  - [Biorhythms. I. Circadian rhythms of concentration of paramagnetic centers in
      normal mouse liver].

PMID- 4371534
TI  - Arterial cannulation in awake restrained monkeys.

PMID- 4371535
TI  - Distribution and persistence of avian encephalomyelitis viral antigens in
      internal organs of naturally infected chickens.

PMID- 4371536
TI  - Distribution of calcium and magnesium in rat kidney homogenate fractions
      accompanying magnesium deficiency induced nephrocalcinosis.

PMID- 4371537
TI  - Distribution of glutamate sensitivity on insect muscle fibres.

PMID- 4371538
TI  - Distribution of sterols in the fungi. I. Fungal spores.

PMID- 4371540
TI  - Centrifugation.

PMID- 4371539
TI  - Distribution of WR-2721 in normal and malignant tissues of mice and rats bearing
      solid tumors: dependence on tumor type, drug dose and species.

PMID- 4371541
TI  - Experimental herpes virus arthritis. Factors in chronicity.

PMID- 4371542
TI  - Experimental investigations on the influence upon the chemical carcinogenesis.
      1st Communication: Studies with ethylnitroso-urea.

PMID- 4371543
TI  - Experimental Zieria arborescens (stinkwood) poisoning in rabbits.

PMID- 4371544
TI  - Description by quasi elastic laser light scattering of a biological preparation:
      sarcoplasmic reticulum vesicles.

PMID- 4371545
TI  - [Pharmacological studies with alkylsulfonyloxyalkyl substituted and chloroethyl
      substituted oxazaphosphorine-2-oxides. 2. Pharmacological characterization of 2
      alkylsulfonyl-oxyalkylamino-oxazaphosphorine-2-oxides including immunological
      reaction].

PMID- 4371546
TI  - Abnormal accumulation of sialoglycoproteins in a case of late infantile amaurotic
      idiocy.

PMID- 4371547
TI  - Abnormal brain scan in Paget's disease of bone-confusion with subdural hematoma.

PMID- 4371548
TI  - Determination of "free" testosterone in plasma by GLC-63Ni ECD.

PMID- 4371549
TI  - Determination of the degree of in vivo tRNA aminoacylation in yeast cells.

PMID- 4371550
TI  - Oncornavirus directed tumor cell surface antigens detectable by humoral and
      cellular immunity.

PMID- 4371551
TI  - [Hydrocyanic acid content of the air in work areas of coking plants].

PMID- 4371552
TI  - Oestrogen receptors and antagonism of steroid hormone action.

PMID- 4371553
TI  - [Neurography. Technic and value].

PMID- 4371554
TI  - Gastrointestinal fibroma. A clinicopathological study.

PMID- 4371555
TI  - Control of phospholipid peroxidation and enzyme activity losses in mitochondria
      by antioxidants.

PMID- 4371556
TI  - Control of uterine blood flow in pregnancy.

PMID- 4371558
TI  - The role of carboxyl, imidazole, and amino groups in inorganic pyrophosphatase of
      baker's yeast.

PMID- 4371557
TI  - The role of calcium in insulin action. II. Effects of insulin and procaine
      hydrochloride on lipolysis.

PMID- 4371559
TI  - The role of choline in maintaining the fine structure of nerve terminals in the
      superior cervical ganglion of cat.

PMID- 4371560
TI  - The role of cyclic nucleotides in the development and function of rat mammary
      tissue.

PMID- 4371561
TI  - The role of cyclic AMP in neoplastic cell growth and regression. II. Growth
      arrest and glucose-6-phosphate dehydrogenase isozyme shift by dibutyryl cyclic
      AMP.

PMID- 4371562
TI  - The role of mineralocorticoids in the pathogenesis of hypokalemic periodic
      paralysis.

PMID- 4371564
TI  - The role of the polyol pathway in methaemoglobin reduction in human red cells.

PMID- 4371563
TI  - The role of platelet membrane phospholipids in the platelet release reaction.
AB  - The structure and function of the platelet surface was probed by phospholipase C
      (Clostridium perfringens) which hydrolyzes membrane phospholipids, particularly
      phosphatidylcholine. Platelet phospholipids were susceptible to phospholipase C,
      and extent of hydrolysis was dependent on concentration of phospholipase C and
      Ca(++). Phospholipase C (0.15 U/ml) with Ca(++) (0.55 mM) hydrolyzed 15.6%
      phospholipids during 5 min. Phospholipase C released platelet serotonin (5HT),
      ADP, and platelet factor 4. Hydrolysis of 5% phospholipids resulted in release of
      70% 5HT. Platelet 5HT release was rapid, occurring within 2 min. Phospholipase C
      (0.2 U/ml) with Ca(++) (0.55 mM) also released 10.35 nmol sotrage pool ADP/10(9)
      platelets and 63% platelet factor 4 during 3 min. Phospholipase C did not cause
      leakage of cytoplasmic metabolic pool ADP, since only 6.6% [(3)H]ADP was
      released. Ultrastructural analysis of phospholipase C-modified platelets showed
      that platelets were intact. After 2% phospholipid hydrolysis, centralization of
      granules and contraction of microtubules were evident. After 18% phospholipid
      hydrolysis, there were morphological indications of degranulation. Phospholipase
      C-induced phospholipid hydrolysis caused the release of ADP and 5HT since: (a)
      Phospholipase C purified by heating was shown to be free of protease and
      neuraminidase activity and capable of inducing the platelet release reaction. (b)
      Antitoxin (Cl. perfringens) neutralized phospholipase C-induced 5HT release which
      rules out a contaminant. (c) Phosphorylcholine, the hydrolysis product, did not
      induce platelet 5HT release. This study demonstrates that minimal hydrolysis of
      platelet phospholipids triggers the release reaction. Our hypothesis is that
      phospholipids, presumably phosphatidylcholine, are situated at or near active
      site or "receptor" on the platelet surface and function as the modulator for the
      release reaction.

PMID- 4371565
TI  - The role of viruses in the etiology of cancer and leukemia.

PMID- 4371566
TI  - The role of Clostridium perfringens in the growth response of chicks to dietary
      penicillin.

PMID- 4371567
TI  - A serological study of antibody to Epstein-Barr virus in an Australian
      population.

PMID- 4371568
TI  - Chlorophyll b containing liposomes: effect of thermal transitions on catalytic
      and spectral properties.

PMID- 4371569
TI  - Hyperostosis corticalis generalisata familiaris.

PMID- 4371570
TI  - [Estrous cycle changes in female white mice resulting from the long-term effect
      of ACTH and zinc sulfate].

PMID- 4371572
TI  - Incorporation of lipid vesicles by mammalian cells provides a potential method
      for modifying cell behaviour.

PMID- 4371571
TI  - Superoxide dismutases.

PMID- 4371574
TI  - Interrelationships of pituitary and plasma corticotrophin and plasma
      corticosterone in adrenalectomized and stressed, adrenalectomized rats.

PMID- 4371573
TI  - Interrelationships among the levels of ATP, adenosine and cyclic AMP in incubated
      slices of guinea-pig cerebral cortex: effects of depolarizing agents,
      psychotropic drugs and metabolic inhibitors.

PMID- 4371575
TI  - Occurrence of carcinoma of the bile ducts: a brief review.

PMID- 4371576
TI  - Reversible inhibition of poliovirus RNA synthesis in vivo and in vitro by viral
      products.
AB  - In poliovirus-infected HeLa-S3 cells, the protease inhibitors tolylsulfonyl
      phenylalanyl chloromethyl ketone and iodoacetamide cause an accumulation of large
      precursor proteins, and they block viral RNA synthesis most probably via these
      products. Viral RNA polymerase activity can, however, be extracted by detergent
      containing buffer (Tris/Nonidet P-40, deoxycholate) from the inhibited cells.
      Only cytoplasmic extracts from infected cells treated with tolylsulfonyl
      phenylalanyl chloromethyl ketone or iodoacetamide contain a protein which
      inhibits the in vitro polymerase reaction.

PMID- 4371577
TI  - Revertants and secondary arom-2 mutants induced in non-complementing mutants in
      the arom gene cluster of Neurospora crassa.
AB  - Extensive genetical and biochemical studies have been performed with revertants
      and secondary arom-2 mutants induced in two different primary non-complementing
      mutants which map within the arom gene cluster of Neurospora crassa. These
      studies indicate that mutant M54 but not M25 can revert by super-suppressor
      mutations in unlinked genes, thus confirming previous evidence that M54 contains
      a nonsense codon. At least three new super suppressors of M54 have been detected.
      All four super suppressors (including one previously detected) when combined with
      M54 result in high levels of all five of the arom enzymic activities in the form
      of arom multienzyme complexes very similar to (but not necessarily identical
      with) that in wild type (WT).-Evidence has also been obtained that the two non
      complementing mutants can yield revertants which appear to result from true back
      mutations and produce arom aggregates essentially indistinguishable from that of
      WT. In addition, M25, but not M54, when plated on quinic acid yields revertants
      (secondary mutants) some of which are phenotypically indistinguishable from arom
      2 primary mutants and others of which, although also mapping within the arom-2
      gene, exhibit unusual properties. Genetic evidence indicates that the M25
      secondary mutants are localized within the arom-2 gene, but that they arise from
      mutational events more complex than ones resulting in single base pair changes in
      the M25 codon.-The recovery of secondary arom-2 mutants as revertants of non
      complementing arom mutants provides strong evidence, independent of earlier
      recombination data, that non-complementing arom mutants are located within the
      arom-2 structural gene of the arom gene cluster. In addition, the occurrence and
      characteristics of these secondary arom-2 mutants provide strong evidence,
      independent of the results with nonsense suppressors, that the arom gene cluster
      is transcribed, beginning with the arom-2 gene, as a single polycistronic
      messenger ribonucleic acid (mRNA) molecule which is subsequently translated into
      the arom multienzyme complex.

PMID- 4371578
TI  - Hypertriglyceridemia and carbohydrate intolerance.

PMID- 4371579
TI  - Bilirubin UDP-glucosyl-and UDP-glucuronosyltransferase of rat liver. A
      comparative study of the effects of membrane perturbants in vitro and of chrysene
      administration in vivo.

PMID- 4371580
TI  - Restructuring medical education for management of the chronically ill aged.

PMID- 4371581
TI  - Observations from longitudinal data on growth in stature and sitting height of
      children with Down's syndrome.

PMID- 4371583
TI  - Observations on the resistance of Fpstein-Barr virus DNA synthesis to
      hydroxyurea.

PMID- 4371582
TI  - Observations on the action of type A botulinum toxin on frog neuromuscular
      junctions.
AB  - 1. Progressive block of neuromuscular transmission in frog sartorius and
      gastrocnemius preparations by haemagglutinin-free crystalline Type A botulinum
      toxin (BTX) was investigated by in vitro application and by injection of the
      toxin into living animals.2. Neuromuscular block was characterized by (a) decline
      in amplitude of evoked twitch contractions, (b) decline in amplitudes of end
      plate potentials (e.p.p.s) and (c) changes in statistical characteristics of
      spontaneous miniature end-plate potentials (m.e.p.p.s).3. Progress of the block
      was enhanced by nerve stimulation.4. A decrease in frequency to less than 0.1/sec
      and decreased average amplitudes of m.e.p.p.s preceded observable impairment of
      neuromuscular transmission. These changes occurred as early as 3 hr after
      injection of the toxin into dorsal lymph sacs.5. The amplitude distributions of
      m.e.p.p.s changed from a normal distribution to one that showed an increased
      skewness toward smaller amplitudes as the block progressed. These changes were
      first detectable as early as 75 min following addition of the toxin to the
      bath.6. At later stages of toxin action, e.p.p.s began to decrease in amplitude
      and eventually failed altogether. E.p.p.s showed a normal quantal variation at
      very early stages in the block in Mg(2+)-treated preparations. At later stages of
      the block, it was not possible to test the quantal make-up of the e.p.p.7. At all
      stages before complete failure it was possible to obtain normal or greater than
      normal degrees of synaptic facilitation with paired stimuli to the nerve. This
      aspect of the coupling of nerve terminal depolarization to transmitter release
      appears to be relatively unaffected by BTX.8. Electrical depolarization of nerve
      terminals in partially blocked preparations evoked a maintained discharge of
      m.e.p.p.s with an amplitude distribution similar to that of the spontaneous
      m.e.p.p.s; hyperpolarization of the terminals evokes a distinctly larger class of
      m.e.p.p.s. In fully blocked preparations, depolarization of the terminals does
      not evoke transmitter release whereas hyperpolarization continues to yield the
      larger class of m.e.p.p.s.9. It is proposed that the neuromuscular block caused
      by BTX is due to impairment of a process by which vesicles become charged with
      transmitter before release.

PMID- 4371584
TI  - A surveillance for Japanese encephalitis (JE) in pigs in southern Taiwan.

PMID- 4371585
TI  - Mucus-producing adenocarcinoma of renal pelvis.

PMID- 4371586
TI  - Air sampling of smallpox virus.
AB  - Airborne smallpox virus has been recovered in an isolation hospital using an
      adhesive surface sampling technique in the presence of very low aerosol
      concentrations. Previous work in this field is reviewed. Successful recovery of
      airborne virus depends on sampling large volumes of air with a suitable sampler
      and thorough investigation of the whole sample taken for the presence of viable
      virus. More information on the characteristics and behaviour of airborne smallpox
      virus is needed in particular with regard to the future design and siting of
      smallpox isolation units.

PMID- 4371587
TI  - Transcutaneous electrical stimulation for control of pain.

PMID- 4371588
TI  - The search for a viral agent in Hodgkin's disease.

PMID- 4371590
TI  - [Possibilities of fluorescence microscopic detection with carbohydrates].

PMID- 4371589
TI  - Viruses and brain tumors.

PMID- 4371591
TI  - The significance of a palpable liver. A correlation of clinical and radioisotope
      studies.

PMID- 4371594
TI  - A gosling disease in Viet-Nam.

PMID- 4371592
TI  - The significance of cyclic 3'5-AMP for the Euler-Liljestrand mechanism.

PMID- 4371595
TI  - Chiasma in the XY bivalent of the Chinese hamster.

PMID- 4371596
TI  - Transmitter-dependent changes of equilibrium characteristics of catecholamine
      synaptosomes in sucrose density gradients.

PMID- 4371593
TI  - Translation products of foot-and-mouth disease virus-infected baby hamster kidney
      cells.

PMID- 4371597
TI  - [Phosphatase activity in the saliva and blood in subjects with intact and carious
      teeth].

PMID- 4371598
TI  - [Phospholipid metabolism in the brain and liver of dogs and albino rats with
      alloxan diabetes].

PMID- 4371599
TI  - Transport of sugars in tumor cell membranes.

PMID- 4371601
TI  - [Fiessinger-Leroy-Reiter syndrome in children. Apropos of a case].

PMID- 4371600
TI  - A possible relation between human pathogenicity of smallpox vaccines and virus
      growth at elevated temperatures.
AB  - Seven smallpox vaccines of known human pathogenicity were tested for their
      ability to produce pocks on the chick chorioallantois at 39.7 degrees C.
      Significant differences were found and the more pathogenic strains produced pocks
      with greater efficiency at 39.7 degrees C. than did strains of average or low
      pathogenicity.

PMID- 4371602
TI  - A test of osteoblasts for hematopoietic competence.

PMID- 4371603
TI  - [Prostaglandin and pancreatic function: endocrine and exocrine functions].

PMID- 4371604
TI  - [Prostaglandin F2alpha (PGF 2alpha) and striated musculature].

PMID- 4371605
TI  - The state of laboratory automation.

PMID- 4371606
TI  - The status of poliomyelitis in Venezuela.

PMID- 4371607
TI  - The stereospecificity of the hydrogen transfer from (R)-carnitine to NAD,
      catalyzed by (R)-carnitine dehydrogenase from Pseudomonas aeruginosa.

PMID- 4371608
TI  - The stimulation of calcium transport in cardiac sarcoplasmic reticulum by
      adenosine 3':5'-monophosphate-dependent protein kinase.

PMID- 4371609
TI  - The stimulatory effect of a serum factor on DNA and protein synthesis in hepatoma
      cells.

PMID- 4371610
TI  - The stimulus-secretion coupling of glucose-induced insulin release. XVI. A
      glucose-like and calcium-independent effect of cyclic AMP.

PMID- 4371611
TI  - Intestinal vasculitis in essential, mixed cryoglobulinemia.

PMID- 4371612
TI  - [Unusual perforation of a duodenal ulcer].

PMID- 4371614
TI  - [Biosynthesis of UDPglucose by rat liver microsomes (author's transl)].

PMID- 4371613
TI  - The synthesis and biological activity of 25,26-dihydroxy-cholecalciferol, a polar
      metabolite of vitamin D3.

PMID- 4371615
TI  - Short communications tissue culture of adult human adrenocortical cells.

PMID- 4371616
TI  - Ergot intoxication: historical review and description of unusual clinical
      manifestations.
AB  - Clinical ergotism as seen today results almost exclusively from the excessive
      intake of ergotamine tartrate in the treatment of migraine headache. Although
      both gangrenous and convulsive symptoms are seen in naturally occurring ergotism
      resulting from the ingestion of fungus infected rye, only gangrenous ergotism has
      been reported following the excessive ingestion of ergotamine tartrate. The
      symptoms of both iatrogenic and naturally occurring ergotism appear to result
      from regional ischemia caused by ergot induced vasospasm. This report discribes
      experiences in the diagnosis and management of two patients with unusual
      manifestations of iatrogenic ergotism. One patient presented with ischemia of all
      extremities and bilateral foot drop probably due to ischemic damage to the common
      peroneal nerves, a finding not previously described in ergot intoxication. The
      foot drop totally resolved in several months following the discontinuation of
      ergot. A second patient presented with unilateral leg ischemia and transient
      monocular blindness, both of which resolved after discontinuation of ergot. Both
      patients displayed typical angiographic findings of ergotism. There is no
      convincing evidence that any treatment other than discontinuation of ergotamine
      is of benefit in the treatment of iatrogenic ergotism.

PMID- 4371617
TI  - Short rib-polydactyly syndromes and related conditions.

PMID- 4371618
TI  - Excitability changes in crayfish motor neurone terminals.
AB  - 1. Changes in the post-activation excitability of crayfish motor nerve terminals
      were used to measure afterpotentials that might be related to facilitation of
      transmitter release.2. The refractory period is followed by a period of
      supernormal excitability in which the threshold of nerve terminals drops to about
      70% of its pre-activation level at about 15 msec following an impulse. The
      threshold returns exponentially to its pre-activation level with a time constant
      of about 25 msec at 13 degrees C. Such a supernormal excitability is rarely seen
      in pre-terminal nerve branches or in the main axon.3. Following a brief high
      frequency tetanus the peak of the supernormal excitability is greater than that
      following a single impulse. At low temperature this peak is reduced and delayed,
      and the decay rate of the supernormal excitability is prolonged with a Q(10) of
      about 2.5.4. Depolarization of nerve terminals decreases, and hyperpolarization
      increases, the magnitude of the post-activation supernormal excitability.5. The
      magnitude of the supernormal excitability depends on the external potassium
      concentration, but not on sodium. In low calcium the peak supernormal
      excitability is often reduced. High calcium concentration and manganese ions have
      no effect, but cobalt abolishes the supernormal excitability, and its effects are
      only slightly reversible. Both cobalt and manganese reversibly block
      neuromuscular transmission.6. Strophanthidin has no effect on the post-activation
      supernormal excitability, but proteolytic enzymes reduce or abolish it, and
      hyperosmotic solutions also affect it.7. It is suggested that the action
      potential is followed by a depolarizing afterpotential in nerve terminals which
      is caused by a transient increase in the potassium concentration around the
      terminals. There is no evidence that afterpotentials in nerve terminals are
      related to facilitation in any way.

PMID- 4371619
TI  - Prostaglandin E1 and fever.

PMID- 4371620
TI  - Spontaneous deaths in rabbits resulting from gastric trichobezoars.

PMID- 4371621
TI  - Spontaneous recovery from severe rickets resembling pseudo-vitamin D deficiency
      rickets.

PMID- 4371622
TI  - A mutant of Pseudomonas putida with altered regulation of the enzymes for
      degradation of phenol and cresols.

PMID- 4371623
TI  - Adaptation in Rhodopseudomonas spheroides.

PMID- 4371624
TI  - Adaptation of influenza virus to growth in cultured murine methylcholanthrene
      induced tumors.

PMID- 4371625
TI  - [Postcoital contraception].

PMID- 4371626
TI  - [Acute infectious enteritis. Some recent aspects].

PMID- 4371627
TI  - A detector tube for the analysis of methyl isocyanate in air or nitrogen purge
      gas;.

PMID- 4371628
TI  - Two temperature-induced changes in mitochondrial membranes detected by spin
      labelling and enzyme kinetics.

PMID- 4371629
TI  - [Letter: Spectral methods of conformational analysis of polypeptides and
      proteins].

PMID- 4371630
TI  - [Letter: Varicella prevention in persons with impaired immunoapparatus].

PMID- 4371631
TI  - Hypothalamic nuclei of rats after head irradiation and adrenocortical hormone
      treatment.

PMID- 4371632
TI  - Hypothalamus as an endocrine organ. II.

PMID- 4371633
TI  - [On the carcinogenic action of methyl- and ethyl-nitrosourea in rats after
      transplacental and postnatal application (author's transl)].

PMID- 4371634
TI  - [On the circle of forms of sclerosing osteoses (author's transl)].

PMID- 4371635
TI  - [On the formation of cytoplasmic vacuoles of leucocytes in vitro. II. Formation
      of cytoplasmic vacuoles in dependence on the experimental influence on the
      stability of membranes (author's transl)].

PMID- 4371637
TI  - [On the selective estimatin methods for beta-and pre beta-lipoproteins (author's
      transl)].

PMID- 4371636
TI  - [On the formation of cytoplasmic vacuoles of leukocytes in vitro. I. Formation of
      cytoplasmic vacuoles in dependence on inflammatory processes (author's transl)].

PMID- 4371638
TI  - [Synthesis and properties of insolubilized enzymes. IV. Covalent binding of
      glucose oxidase to dialdehyde Epidex and dialydehyde cellulose].

PMID- 4371639
TI  - Hypothesis: Inhibition of E prostaglandin-sensitive adenyl cyclase as the
      mechanism of morphine analgesia.

PMID- 4371640
TI  - A method for the detection of starch hydrolysis by bacteria.

PMID- 4371641
TI  - A method for the determination of polyamines in cerebrospinal fluid.

PMID- 4371642
TI  - Parathyroid hormone (PTH)-mediated rise in urinary cyclic AMP(UcAMP) during acute
      extracellular fluid (ECF) expansion natriuresis in man.

PMID- 4371644
TI  - Genetic analysis of mutations affecting growth of Saccharomyces cerevisiae at low
      temperature.
AB  - A large number of genes control growth of the yeast Saccharomyces cerevisiae at
      low temperatures (< 10 degrees ). Approximately 47 percent of the mutants
      selected for inability to grow at 4-5 degrees C show increased sensitivity to
      cycloheximide. In 3 of 4 cases tested, supersensitivity to cycloheximide and
      inability to grow at the low temperature segregate together and thus appear to be
      effects of the same mutation. Since many cold-sensitive mutants of bacteria have
      been found to have altered ribosomes and since cycloheximide resistance in yeast
      can be caused by ribosomal changes, this suggests that the mutants having low
      temperature-sensitive growth may be defective in ribosome-assembly processes at
      the low temperatures. Two of the lts loci, lts1 and lts3 have been located on
      chromosome VII and another two, lts4 and lts10 on chromosome IV. A mutation,
      cyh10, conferring cycloheximide resistance, but not cold sensitivity, has been
      located close to the centromere on chromosome II.

PMID- 4371643
TI  - Hepatic amoebiasis. A study of 32 cases in the Western Cape.

PMID- 4371645
TI  - Kinetic approach to the development in beta-lactam antibiotics. I. Comparative
      stability of semisynthetic penicllins and 6-aminopenicillanic acid in aqueous
      solution.

PMID- 4371647
TI  - Hepatic copper-and zinc-binding proteins in ruminants. 1. Distribution of Cu and
      Zn among soluble proteins of livers of varying Cu and Zn content.

PMID- 4371646
TI  - Somatic cell hybrids between mouse peritoneal macrophages and SV40-transformed
      human cells. I. Positive control of the transformed phenotype by the human
      chromosome 7 carrying the SV40 genome.
AB  - Fusion of mouse peritoneal macrophages with SV40-transformed human cells,
      deficient in hypoxanthine guanine phosphoribosyltransferase, resulted in the
      formation of transformed somatic cell hybrids which contained, without exception,
      the human chromosome 7 carrying the SV40 genome. It is postulated that the
      hybridization of mouse nondividing cells with human cancer cells could permit the
      identification of the human "oncogenic" chromosome(s) present in human cancer
      cells, since such chromosome(s) should be retained by the totality of the mouse
      human hybrid cells.

PMID- 4371648
TI  - Genetic manipulation of an abnormal jump response in Drosophila.
AB  - The hyperkinetic mutants, Hk(1) and Hk(2), jump and fall over when an object
      moves near them. This behavior, the kinetogenic response, has been measured by
      the experimenter moving his hand above a vial containing a single fly and scoring
      the number of positive responses in fifty trials. The response is higher in Hk(1)
      than in Hk(2) and has remained so over a period of several years and in different
      genetic backgrounds. The Hk(1)/Hk(2) heterozygote also responds to movements,
      establishing the allelism of the two mutants.-When Sh(5), a shaker mutant at
      another locus on the X chromosome, is introduced into the same chromosome as
      Hk(1) or Hk(2), the response is reduced in proportion to the number of Sh(5)
      mutant genes added.-When Hk(1) or Hk(2) is heterozygous with a deficiency for the
      hyperkinetic region of the X chromosome, the expression is more abnormal than the
      respective Hk(1) or Hk(2) homozygote. This shows that the mutant genes are
      producing an altered gene product, or less of the normal, since one mutant gene
      by itself has a more abnormal expression than two. A tentative explanation has
      been offered for the observed mutant behaviors.

PMID- 4371649
TI  - Kinetic regulation of adenylate kinases from muscle, liver, and hepatoma.

PMID- 4371650
TI  - Kinetics of allosteric enzymes.

PMID- 4371651
TI  - Kinetics of ligand-binding and oxidation-reduction reactions of cytochrome c from
      horse heart and Candida krusei.

PMID- 4371652
TI  - Kinetics of pyrophosphate-ATP exchange catalysed by L-tryptophan: tRNA ligase
      from Escherichia coli.

PMID- 4371653
TI  - Deletion analysis of two nonessential regions of the T4 genome.

PMID- 4371654
TI  - Function and structure of plasma lipoproteins.

PMID- 4371655
TI  - Rotational and translational diffusion in membranes.

PMID- 4371656
TI  - Functional correlates of dopamine neurotransmission.

PMID- 4371657
TI  - Functional development of the autonomic innervation of the human fetal heart.

PMID- 4371658
TI  - Fractionation and molecular weight determination of deoxyribonucleic acid
      fragments using agarose column chromatography.

PMID- 4371659
TI  - Fractionation of islet tissue in processing proinsulin to insulin.

PMID- 4371660
TI  - Relationship between SMON virus and avian infectious laryngotracheitis virus.

PMID- 4371661
TI  - [Multiplication of Mycobacterium lepraemurium in cell-free liquid medium. 3.
      Factors affecting the growth of M. lepraemurium in the NC medium (author's
      transl)].

PMID- 4371662
TI  - [Multiplication of Mycobacterium lepraemurium in cell-free liquid medium. 4.
      Establishment of the NC-3 medium (author's transl)].

PMID- 4371663
TI  - Quantitation of endogenous C-type virion production in several murine cell lines.
AB  - Quantitation by enumeration of virion particles, measurement of absorbancy at 260
      nm, and densitometry on sodium dodecyl sulfate-polyacrylamide gels has shown that
      mouse L-M cells yielded 7- to 10-fold less endogenous C-type virions than the
      parental lines, L or L929. The previously noted stimulation of L-M cell virion
      production by a concomitant 10% increase in fetal calf serum concentration (D. A.
      Kindig, R. Karp, and W. H. Kirsten, 1968), was not observed.

PMID- 4371664
TI  - Quantitative genetic studies of the human plasma Lp(a) lipoprotein.

PMID- 4371665
TI  - Hepatitis and brain lesions due to mouse hepatitis virus accompanied by wasting
      in nude mice.

PMID- 4371667
TI  - Hepatitis A: in vitro isolation of an agent with unusual growth requirements from
      a clinical case occurring in Costa Rica.

PMID- 4371666
TI  - Hepatitis following actinomycin D and irradiation.

PMID- 4371668
TI  - Hepatitis-associated antigen, cirrhosis and hepatoma in Rhodesia.

PMID- 4371669
TI  - Relative dependence on intracellular cyclic adenosine-3',5'-monophosphate levels
      of catabolite repressible proteins in Escherichia coli.

PMID- 4371670
TI  - Positive mediastinoscopy. An ominous finding.

PMID- 4371673
TI  - [Histological diagnosis of respiratory diseases in pigs].

PMID- 4371671
TI  - Reactivity of chick embryo heart to cholinergic agonists during ontogenesis:
      decline in desensitization at the onset of cholinergic transmission.

PMID- 4371672
TI  - Treatment of childhood asthma for 13 months and longer with beclomethasone
      dipropionate aerosol.

PMID- 4371674
TI  - Symptomatic porphyria. I. The pathology of the liver in human symptomatic
      porphyria.

PMID- 4371676
TI  - [Pantopaque embolus through a ventriculo-atrial shunt during ventriculography (a
      case report) (author's transl)].

PMID- 4371675
TI  - Symptomatic porphyria. II. Hepatic changes with hexachlorobenzene.

PMID- 4371678
TI  - [History and terminology of the FP Weber and Klippel-Trenaunay syndromes].

PMID- 4371677
TI  - [Factors affecting the function of the gall bladder and biliary ducts. The
      physiology of gall bladder filling (author's transl)].

PMID- 4371679
TI  - Somatostatin inhibition of rat growth hormone release in vitro in the presence of
      BaCl2 or 3-isobutyl-1-methylxanthine.

PMID- 4371680
TI  - Spectral and catalytic properties of cytochrome P-450 from a diazinon-resistant
      housefly strain.

PMID- 4371681
TI  - Spectral resolution of four cytochrome b components in mitochondria.

PMID- 4371682
TI  - [Distribution of NAD-deaminase activity in brain tissue subcellular fractions].

PMID- 4371684
TI  - Clostridium perfringens in the environment.
AB  - Clostridium perfringens was isolated from samples collected in Puget Sound in the
      state of Washington and areas considered as possible sources of these organisms
      to Puget Sound. The distribution of C. perfringens in the total Clostridium
      population was determined for fish gut contents and sediments collected in highly
      polluted and less polluted areas, sewage samples, freshwater sediments, and
      soils. The greatest numbers of C. perfringens were obtained from marine sediments
      collected near the sewage outfall at West Point. Fewer isolates were made from
      fish collected from less polluted stations, although the number of C. perfringens
      remained high in sediments from other Puget Sound stations. The proportion of C.
      perfringens in the total Clostridium populations varied between 56 and 71% for
      sewage samples and only 0.4 to 4.1% for freshwater sediments and soil samples.
      Only 25 C. perfringens isolates out of 137 from fish guts, or 18%, were
      identifiable serologically and these fell into 12 groups. C. perfringens were fed
      to fish and the fish were sacrificed after varying lengths of time. The number of
      C. perfringens increased slightly in the gut during the first 24 h and then the
      numbers decreased rapidly for the next 120 h.

PMID- 4371683
TI  - Electrical activity of gastrointestinal smooth muscle.

PMID- 4371685
TI  - Electron microscopic demonstration of insulin receptors on adipocyte plasma
      membranes utilizing a ferritin-insulin conjugate.

PMID- 4371687
TI  - Electron microscopy of single-stranded RNA from vesicular stomatitis virus.

PMID- 4371686
TI  - Electron microscopic observations on infectious bovine rhinotracheitis virus in
      bovine fetal tracheal organ cultures.

PMID- 4371688
TI  - Electron spin resonance of manganese(II)-substituted zinc(II) metalloenzymes.

PMID- 4371689
TI  - Electron spin resonance spectra from whole blood of cancer patients.

PMID- 4371691
TI  - Electron-spin resonance of an X-irradiated single crystal of N-acetyl-DL-valine.

PMID- 4371690
TI  - Electron-paramagnetic-resonance studies on cobalt(II) carbonic anhydrase. Low
      spin cyanide complexes.
AB  - The low-spin cyanide complexes of three Co(II) carbonic anhydrases were
      investigated by electron paramagnetic resonance (e.p.r.) at 9 and 35GHz. Well
      defined and closely axial spectra were obtained only in the absence of oxygen.
      Several mole equivalents of cyanide were required for complete formation of the
      complexes in frozen solution, although large excesses caused abstraction of the
      cobalt. Experiments with [(13)C]cyanide showed that the low-spin complexes
      contained two CN(-) groups in an environment similar to that of the in-plane
      ligands in [Co(CN)(5)](3-). A combined e.p.r. and spectrophotometric titration
      confirmed the presence of two CN(-) ligands. A 5-co-ordinate square pyramidal
      structure involving three protein ligands was proposed. The dicyanide complex
      could be oxygenated reversibly, producing a characteristic new e.p.r. spectrum.
      The O(2) molecule was thought to occupy the remaining octahedral metal site in a
      formally Co(III) species. The optical spectrum of the dicyanide lacked the
      prominent d-d bands of the high-spin monocyanide. Both e.p.r. and optical data
      indicated that the low-spin complex was formed much more fully in frozen solution
      than at room temperature. Differences in behaviour between the high- and low
      activity enzymes suggested some variation in conformational flexibility at the
      metal binding site.

PMID- 4371694
TI  - An attempt to identify putative neurotransmitter substance released from the non
      adrenergic inhibitory fibers in the vagal supply to the guinea-pig stomach.

PMID- 4371692
TI  - The trophic responses of cultured adrenocortical cells to ACTH.

PMID- 4371693
TI  - Electrophoretic polymorphism of adenylate kinase in human jejunum.

PMID- 4371695
TI  - An attempt to localize cyclic phosphodiesterase at adrenergic nerve endings.

PMID- 4371696
TI  - [Bertter' syndrome in an 8-year-old child].

PMID- 4371697
TI  - Denaturation of the normal and abnormal hemoglobin molecule.

PMID- 4371700
TI  - Evaluation of serum dopamine-beta-hydroxylase activity as an index of sympathetic
      nervous activity in man.

PMID- 4371698
TI  - Dibutyryl cyclic adenosine 3',5-monophosphate and brain lipid metabolism.

PMID- 4371702
TI  - [Induction of "epinephrine myocarditis" by hypertensin. Light- and electron
      microscopic studies (author's transl)].

PMID- 4371699
TI  - Evaluation of a plaque assay for the maedi-progressive pneumonia-visna viruses.
AB  - A simple and direct plaque assay for maedi virus, two strains of progressive
      pneumonia virus, and two strains of visna virus has been developed and evaluated.
      The technique allows the plaques formed by these viruses to be localized without
      disturbing the host-cell substrate of sheep choroid plexus cells or the gelled
      maintenance medium over the host-cell monolayer. Diethylaminoethyl-dextran
      supplementation of the medium used to overlay strain K796 visna virus-infected
      cultures decreases the time required for maximum plaque development from 12 to 10
      days, enhances the contrast of the plaques, increases the titer of plaque-forming
      units, and permits a plaque size heterogeneity to be realized. Both large and
      small plaques occur in cultures infected with the visna viruses, one strain of
      progressive pneumonia virus, or maedi virus. In contrast, the plaques observed in
      cultures infected with the second strain of progressive pneumonia virus are
      relatively homogeneous in size.

PMID- 4371701
TI  - Production and localization of the secretory component in tumours of the exocrine
      glands.

PMID- 4371703
TI  - Production of sindbis, influenza, and vesicular stomatitis viruses in chicken
      embryo and rat embryo cell suspensions.

PMID- 4371704
TI  - [Structural and histochemical changes in the neuroglia cultured in vitro and
      subjected to the action of carbon monoxide].

PMID- 4371706
TI  - A study of tumors of the parapharyngeal space.

PMID- 4371705
TI  - A study of the relationships between carbon tetrachloride-induced lipid
      peroxidation and liver damage in rats pretreated with vitamin E.

PMID- 4371708
TI  - Tissue androgens and androphilic proteins in rat epididymis during sexual
      development.

PMID- 4371707
TI  - A study of urolithiasis in grazing ruminants in South Australia.

PMID- 4371709
TI  - Tissue sensitivity to drugs in disease states.

PMID- 4371710
TI  - Influence of adrenal steroids on liver enzymes of neonatally castrated rats.

PMID- 4371711
TI  - Influence of corticotrophic and corticosteroid hormones on the output of cells
      from the popliteal lymph node of the sheep.

PMID- 4371712
TI  - Influence of immunosuppressive drugs on replication of Col MM virus and
      productive of interferon in vivo.

PMID- 4371713
TI  - Influence of membrane phosphatidylinositol content on the activity of bovine
      brain phospholipid transfer protein.

PMID- 4371714
TI  - Influence of the hormonal forms of ACTH on the pattern of corticosteroid
      secretion.

PMID- 4371715
TI  - Influence of the socio-economic level on the conception rate during lactation.

PMID- 4371716
TI  - Cellular and humoral immune interactions during neoplastic development.

PMID- 4371718
TI  - Cellular distribution of nicotinamide adenine dinucleotide glycohydrolase in the
      central nervous system.

PMID- 4371717
TI  - Granular cells and granular cell lesions.

PMID- 4371719
TI  - [Regulation and translation of eukaryotic cells. I. Efficacy of cytosol-fraction
      from normal and tumorous tissue on ribosomal protein synthesis].

PMID- 4371720
TI  - [Regulation of citrate synthase activity in Acinetobacter calcoaceticus].

PMID- 4371721
TI  - Stimulation of hepatic triglyceride synthesis and secretion by clofibrate.

PMID- 4371722
TI  - Stimulation of mitochondrial DNA synthesis as an early function of herpes simplex
      virus.

PMID- 4371723
TI  - Stimulation of ribosomal and DNA-like RNA synthesis by alpha-methyltryptophan.

PMID- 4371724
TI  - Stimulation of the posterior columns of the spinal cord for pain control:
      indications, technique, and results.

PMID- 4371725
TI  - Stimulation of thymidine kinase induction by polyoma virus in cells "prelabeled"
      with 5-bromo-2'-deoxyuridine.

PMID- 4371726
TI  - The ultrastructure of cytoplasmic inclusions in circulating lymphocytes in canine
      distemper.

PMID- 4371728
TI  - [Serum determination of 3 lysosomal enzymes as criterion of the reversability of
      hepatocellular lesions].

PMID- 4371727
TI  - The ultrastructure of neuroblastoma glioma somatic cell hybrids. Expression of
      neuronal characteristics stimulated by dibutyryl adenosine 3',5' cyclic
      monophosphate.

PMID- 4371729
TI  - Conjunctival bacterial flora of the clinically normal New Zealand white rabbit.

PMID- 4371730
TI  - [Immunhistologic, cytochemical, and electron-microscopic investigations in Verner
      Morrison syndrome (WDHA-syndrome, pancreatic cholera) (author's transl)].

PMID- 4371732
TI  - [Immunologic surveillance of broncho-pulmonary cancers treated by massive doses
      of methotrexate].

PMID- 4371731
TI  - [Immunochemical characteristics of glucose-6-phosphatase in rat liver and
      kidney].

PMID- 4371733
TI  - Disruption of drinking to intracranial angiotensin by a lateral hypothalamic
      lesion.

PMID- 4371734
TI  - [Saturation effect in relation to microwave field power of paramagnetic centers
      of proteins irradiated with ultraviolet light].

PMID- 4371735
TI  - Failure of cytochrome C to cure experimental Amanita phalloides poisoning.

PMID- 4371736
TI  - Failure to demonstrate serotonergic neurons in the myenteric plexus of the rat.

PMID- 4371737
TI  - Tumours and dysplasias of the mammary gland.
AB  - As mammary tumours occur frequently in the dog and cat but rarely in other
      domestic animals, only the tumours of these two species are classified. The
      epithelial tumours are termed "complex" when they consist of cells resembling
      both secretory and myoepithelial cells: these tumours are biologically less
      malignant than tumours of the "simple" type in which only one of these kinds of
      cell is present. The carcinomas are subdivided into adenocarcinoma, solid
      carcinoma, spindle cell carcinoma, anaplastic carcinoma, squamous cell carcinoma,
      and mucinous carcinoma. The term "carcinosarcoma or malignant mixed tumour" was
      used only when there were cells morphologically resembling not only one or both
      of the epithelial components but also connective tissue cells with their products
      of differentiation. The benign tumours are classed as adenoma, papilloma,
      fibroadenoma, or benign soft tissue tumour. The dysplasias are described under
      the following headings: cyst, adenosis, regular typical epithelial proliferation
      in ducts and lobules (epitheliosis), duct ectasia, fibrosclerosis, and lobular
      hyperplasia.

PMID- 4371738
TI  - Tumours of the lung.
AB  - Lung tumours are not common in domestic animals; there has not been the increase
      in epidermoid carcinomas and anaplastic small-cell carcinomas that has occurred
      in man this century. Adenocarcinoma is the most common type in animals. The
      biological behaviour of each type of tumour in animals seems to be much the same
      as in man. The tumours are described histologically, the main categories being:
      epidermoid carcinoma, anaplastic carcinoma, adenocarcinoma, combined epidermoid
      and adenocarcinoma, carcinoid tumours, bronchial gland tumours, benign tumours,
      and sarcomas.

PMID- 4371739
TI  - Tumours of the nervous system.
AB  - Tumours of the nervous system of animals are not as rare as has been commonly
      believed. In dogs, especially the brachycephalic breeds, these tumours occur as
      frequently as in man. The tumours are grouped according to tissue of origin as
      follows: nerve cells, neuroepithelium, glia, peripheral nerves and nerve sheaths,
      meninges and vessels, the pineal and pituitary glands, and the craniopharyngeal
      duct. Tumours of the glia are relatively common and are divided into the
      following types: astrocytoma, oligodendroglioma, glioblastoma, spongioblastoma,
      medulloblastoma, and unclassified gliomas.

PMID- 4371740
TI  - Tumours of the soft (mesenchymal) tissues.
AB  - This is a classification of tumours of fibrous tissue, fat, muscle, blood and
      lymph vessels, and mast cells, irrespective of the region of the body in which
      they arise. Tumours of fibrous tissue are divided into fibroma, fibrosarcoma
      (including "canine haemangiopericytoma"), other sarcomas, equine sarcoid, and
      various tumour-like lesions. The histological appearance of the tumours is
      described and illustrated with photographs.

PMID- 4371741
TI  - Tumours of the urinary bladder.
AB  - Tumours of the urinary bladder are uncommon in all domestic animals except cattle
      in certain regions. Where cattle eat bracken (Pteridium aquilinum) there is a
      high incidence of these tumours. Epithelial tumours are the most frequently
      encountered neoplasms in cattle and in dogs-the two species most studied. They
      are described under the following names: papilloma, adenoma, transitional cell
      carcinoma (with variants), squamous cell carcinoma, adenocarcinoma, and
      undifferentiated carcinoma.

PMID- 4371742
TI  - Status of the endogenous avian leukosis virus in resistant cells from a producing
      line.

PMID- 4371743
TI  - The use of continuous preparative free-flow electrophoresis for dissociating cell
      fractions and isolation of membranous components.

PMID- 4371744
TI  - The use of non-professional change agents in an institution.

PMID- 4371745
TI  - The use of oestrogen-progestogen preparations in the treatment of hirsutism in
      the female.

PMID- 4371746
TI  - The use of BSVR-SrCr mice for detection of murine strains of toxigenic
      Escherichia coli.

PMID- 4371747
TI  - The use of CI 744 as an anesthetic for laboratory animals.

PMID- 4371748
TI  - Computerized primate information retrieval system (PIRS).

PMID- 4371749
TI  - The validity of comparing the measurements of angiotensin I generated in human
      plasma by radioimmunoassay and bioassay.

PMID- 4371750
TI  - Salivary gland scintiphotography.

PMID- 4371751
TI  - Renovascular hypertension. A clinical and laboratory study.

PMID- 4371752
TI  - The vasopressin-sensitive adenylate cyclase of the rat kidney. Effect of
      adrenalectomy and corticosteroids on hormonal receptor-enzyme coupling.

PMID- 4371753
TI  - Pryuvate as substrate in the determination of serum lactate dehydrogenase
      isoenzyme activity.

PMID- 4371754
TI  - Pyruvate carboxylase from chicken liver. Magnetic resonance studies of the effect
      of substrates and inhibitors on the environment of the bound manganese.

PMID- 4371755
TI  - Activation and dissociation of adenosine 3'-5'-monophosphate-dependent and
      guanosine 3'-5'-monophosphate-dependent protein kinases by various cyclic
      nucleotide analogs.

PMID- 4371756
TI  - Activation of lipoprotein lipase in vitro by unsaturated phospholipids.

PMID- 4371757
TI  - Active transport of exogenous S-adenosylmethionine and related compounds into
      cells and vacuoles of Saccharomyces cerevisiae.
AB  - Saccharomyces cerevisiae 4094-B (alpha, ade-2, ura-1) in potassium phosphate
      buffer with glucose under aerobic conditions took up (-)S-adenosyl-l-methionine
      from the medium in sufficient quantity to permit the demonstration of its
      accumulation in the vacuole by ultraviolet micrography. The same result was
      obtained with (+/-)S-adenosyl-l-methionine, (+/-)S-adenosyl-d-methionine, and (
      )S-adenosyl-l-ethionine. The rate of uptake was slow with (-)S-adenosyl-S(n
      propyl)-l-homocysteine and S-adenosyl-d-homocysteine. S-Adenosyl-l-homocysteine
      was assimilated rapidly, but intracellular degradation precluded accumulation and
      ultraviolet micrographic studies. The uptake of 5'-methyl-, 5'-ethyl-, 5'-n
      propylthioadenosine, and 5'-dimethylsulfonium adenosine was minimal.

PMID- 4371759
TI  - Recovery of adenoviruses and slow herpesviruses from horses having respiratory
      tract infection.

PMID- 4371760
TI  - Recovery of herpes simplex virus from human sacral ganglions.

PMID- 4371758
TI  - A novel respiration-deficient mutant of Saccharomyces cerevisiae. I. Preliminary
      characterization of phenotype and mitochondrial inheritance.

PMID- 4371762
TI  - Synovial sarcoma arising from the lower end of the femur.

PMID- 4371761
TI  - Recovery of DNA-dependent RNA polymerase activities from L cells after mengovirus
      infection.

PMID- 4371763
TI  - Synovial sarcoma of the head and neck.

PMID- 4371764
TI  - Synovial sarcoma of the tongue, report of a case.

PMID- 4371765
TI  - Behavioral effects of direct- and indirect-acting dopaminergic agonists.

PMID- 4371766
TI  - Behavioral manifestations of competition of retinal endings for sites in doubly
      innervated frog optic tectum.

PMID- 4371767
TI  - Behavioral modulation of the cardiovascular effects of l-norepinephrine in the
      squirrel monkey.

PMID- 4371768
TI  - Behaviour of flagella isolated from Crithidia oncopelti.

PMID- 4371769
TI  - Behaviour of rat-liver mitochondria during centrifugation in a sucrose gradient.

PMID- 4371770
TI  - Activity of reduced ubiquinone: cytochrome c oxidoreductase with various
      ubiquinol-isoprenologues as substrate and corresponding inhibitory effect of
      antimycin in yeast.

PMID- 4371771
TI  - A new approach for selecting patients with metastatic breast cancer for
      hypophysectomy.

PMID- 4371772
TI  - A new class of lipopolysaccharide from Thermoplasma acidophilum.

PMID- 4371773
TI  - A new fluorimetric procedure for the detection and quantitation of organic
      compounds in thin-layer chromatography.

PMID- 4371774
TI  - A low molecular weight ruthenium complex inhibitory to mitochondrial Ca2+
      transport.

PMID- 4371775
TI  - A new, sensitive detector for liquid chromatography: the spray impact detector.

PMID- 4371776
TI  - [Growth hormone secretion during sleep].

PMID- 4371777
TI  - An examination of the metabolism of thiamin by rat liver alcohol dehydrogenase.

PMID- 4371778
TI  - Autoxidation as a cause of antibacterial activity in unsaturated fatty acids.

PMID- 4371779
TI  - An extracellular nuclease from suspension cultures of tobacco.

PMID- 4371780
TI  - On extraction of acyl and alkyl dihydroxyacetone phosphate from incubation
      mixtures.

PMID- 4371781
TI  - Fully automated, all-enzymatic triglyceride method adapted to the GEMSAEC
      centrifugal analyzer, with use of an aqueous triolein standard.

PMID- 4371782
TI  - Study of nucleolar vacuolation and RNA synthesis in embryonic root cells of Zea
      mays.

PMID- 4371783
TI  - Epoxy-fiberglass adsorbent for concentrating viruses from large volumes of
      potable water.
AB  - A simple and compact virus-adsorbing unit for efficiently concentrating human
      enteric viruses from 100 gallons (about 380 liters) or more of potable water is
      described.

PMID- 4371784
TI  - Prolyl hydroxylase.

PMID- 4371785
TI  - Adenylate cyclase activity in rat adipocyte plasma membranes after adrenalectomy
      and administration of cortisone acetate. Effects of calcium ions and hormonal
      stimulations.

PMID- 4371786
TI  - Acetylglutamate kinase: a feedback-sensitive enzyme of arginine biosynthesis in
      Neurospora.

PMID- 4371787
TI  - Biosynthesis of collagen and elastin by chick embryo skin during maturation.

PMID- 4371788
TI  - Biosynthesis of oligogalactosyl side chains of the cell envelope glycoprotein of
      Cryptococcus laurentii.

PMID- 4371789
TI  - Analysis of penicillic acid by gas-liquid chromatography.

PMID- 4371791
TI  - [ACTH and cortisol serum level in women with glaucoma simplex].

PMID- 4371792
TI  - The Klippel-Trenaunay-Weber syndrome.

PMID- 4371790
TI  - Analytical fractionation of homogenates from cultured rat embryo fibroblasts.
AB  - Homogenates of cultured rat embryo fibroblasts have been assayed for acid
      phosphatase, N-acetyl-beta-glucosaminidase, cathepsin D, acid deoxyribonuclease,
      cytochrome oxidase, NADH cytochrome c reductase, 5'-nucleotidase, inosine
      diphosphatase, acid pyrophosphatase, neutral pyrophosphatase, esterase, catalase,
      cholesterol, and RNA. The validity of the assay conditions was checked. Neutral
      pyrophosphatase is a readily soluble enzyme. Acid hydrolases, except acid
      pyrophosphatase, are particle-bound enzymes, which exhibit a high degree of
      structural latency. They are activated and solubilized in a parallel fashion by
      mechanical treatments and tensio-active agents. Catalase is also particle-bound
      and latent; activating conditions stronger than those for hydrolases are required
      to activate the enzyme. Acid pyrophosphatase, 5'-nucleotidase and inosine
      diphosphatase are firmly particle-bound, but not latent; they are not easily
      solubilized. In differential and isopycnic centrifugation, the latent hydrolases,
      cytochrome oxidase and catalase dissociate largely from each other; this suggests
      the occurrence of lysosomes and peroxisome-like structures besides mitochondria.
      The distribution patterns of 5'-nucleotidase and cholesterol are largely similar;
      digitonin influences their equilibrium density to the same extent; these two
      constituents are thought to be related to the plasma membrane. Inosine
      diphosphatase and acid pyrophosphatase are also partially associated with the
      plasma membrane, although some part of these enzymic activities probably belongs
      to other structures. NADH cytochrome c reductase is associated partly with the
      endoplasmic reticulum, partly with mitochondria.

PMID- 4371793
TI  - The Mn2+-activated incorporation of inositol into molecular species of
      phosphatidylinositol in rat liver microsomes.

PMID- 4371794
TI  - [Klippel-Trenaunay-Weber syndrome].

PMID- 4371795
TI  - [Puncture and perineal injection as a method for the diagnosis of anorectal
      malformations].

PMID- 4371797
TI  - [Studies on the possibility of a correlation between canine hepatitis virus
      (Rubarth's disease) and human hepatitis virus. II. Research on canine hepatitis
      antigen (CHA) and specific antibody in normal human serums].

PMID- 4371796
TI  - [Studies on the possibility of a correlation between canine hepatitis virus
      (Rubarth's disease) and human hepatitis virus. I. Research on the human hepatitis
      antigen (HHAg) and specific antibody in dog serum].

PMID- 4371798
TI  - [Studies on the possibility of a correlation between canine hepatitis virus
      (Rubarth's disease) and human hepatitis virus. III. Attempt to demonstrate an
      antigenic affinity between canine hepatitis virus (CHV) and human hepatitis
      antigen (HBAg)].

PMID- 4371799
TI  - [Abortive transformation of rabbit cells infected in vitro with polyoma virus].

PMID- 4371800
TI  - [Vestibulo-oculomotor reflexes in relation to the level of vigilance. I.
      Pathological nystagmus and nocturnal sleep].

PMID- 4371801
TI  - [Anti-spermatogenic effect of seminal ribonuclease (BS-1 RNase)].

PMID- 4371802
TI  - [Effect of tryptophan on the somatotropic hormone during sleep in
      schizophrenics].

PMID- 4371803
TI  - Copper and zinc levels in peripheral nerve tissues of rats with experimental
      carbon-disulphide neuropathy.

PMID- 4371804
TI  - A study of the histological cell types of lung cancer in workers suffering from
      asbestosis in the United Kingdom.

PMID- 4371805
TI  - What a dream is.

PMID- 4371806
TI  - Relapsing polychondritis and eye disease.

PMID- 4371807
TI  - Focal dermal hypoplasia.

PMID- 4371808
TI  - Imidazole catalysis of amino proton exchange in 2',3'-cyclic adenosine
      monophosphate. A general exchange mechanism.

PMID- 4371809
TI  - Physical and chemical properties of rabbit muscle phosphofructokinase cross
      linked with dimethyl suberimidate.

PMID- 4371810
TI  - A homogeneous, thermostable deoxythymidine kinase from Bacillus
      stearothermophilus.

PMID- 4371811
TI  - The phosphorylation of ribavirin by deoxyadenosine kinase from rat liver.
      Differentiation between adenosine and deoxyadenosine kinase.

PMID- 4371812
TI  - Biosynthesis of cartilage procollagen. Influence of chain association and
      hydroxylation of prolyl residues on the folding of the polypeptides into the
      triple-helical conformation.

PMID- 4371813
TI  - Ferrous porphyrins in organic solvents. II. Optical spectra and paramagnetic
      susceptibilities.

PMID- 4371814
TI  - Structure of the primary acid rearrangement product of reduced nicotinamide
      adenine dinucleotide (NADH).

PMID- 4371815
TI  - Glyceraldehyde-3-phosphate dehydrogenase catalyzed hydration of the 5-6 double
      bond of reduced beta-nicotinamide adenine dinucleotide (betaNADH). Formation of
      beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide.

PMID- 4371816
TI  - Topography of 16S RNA in 30S ribosomal subunits. Nucleotide sequences and
      location of sites of reaction with kethoxal.

PMID- 4371817
TI  - Purification and characterization of two forms of geranyl transferase from
      Ricinus communis.

PMID- 4371818
TI  - Trypsin-modified isoleucyl transfer ribonucleic acid synthetase with partial
      retention of activity.

PMID- 4371819
TI  - Structure of the major complex formed by interaction of phosphatidylcholine
      bilamellar vesicles and apolipoprotein-alanine (APO-C-III).

PMID- 4371820
TI  - The dynamic structure of fatty acyl chains in a phospholipid bilayer measured by
      deuterium magnetic resonance.

PMID- 4371821
TI  - The reactivity of conformationally modified cytochrome c.

PMID- 4371822
TI  - Mechanism of the mutagenic action of hydroxylamine. VII. Functional activity and
      specificity of cytidine triphosphate modified with hydroxylamine and O
      methylhydroxylamine.

PMID- 4371823
TI  - Effects of temperature-induced phase changes in membranes on protein synthesis by
      bound ribosomes.

PMID- 4371824
TI  - Ribosomal and soluble protein synthesis during a nutritional shift-up. Influence
      of cyclic AMP on beta-galactosidase activity.

PMID- 4371825
TI  - Steroid-protein interactions. XXX. A progesterone-binding protein in the uterine
      cytosol of the pregnant guinea pig.

PMID- 4371826
TI  - Enzymatic repair of x-ray-damaged DNA. I. Labeling of the precursor of a
      malonaldehyde-like material in X-irradiated DNA and the enzymatic excision of
      labeled lesions.

PMID- 4371827
TI  - Low molecular weight DNA polymerase of rat ascites hepatoma cells.

PMID- 4371828
TI  - Characterization of the 5'-terminus of murine leukemia virus RNA.

PMID- 4371829
TI  - ESR evidence for the radiation-induced breakage of the sugar-phosphate bonds in
      nucleotides: single crystal of deoxycytidine 5'-monophosphate.

PMID- 4371830
TI  - Effect of cyclic AMP on nucleoside metabolism. III. Effect on uridine
      incorporation in monkey (CV-1) cells.

PMID- 4371831
TI  - Purification of pig heart mitochondrial membranes. Enzymatic and morphological
      characterization as compared to microsomes.

PMID- 4371832
TI  - Studies on Tetrahymena membranes: temperature-induced alterations in fatty acid
      composition of various membrane fractions in Tetrahymena pyriformis and its
      effect on membrane fluidity as inferred by spin-label study.

PMID- 4371833
TI  - Chain ordering in liquid crystals. II. Structure of bilayer membranes.

PMID- 4371834
TI  - A plasma membrane fraction from bovine adrenal medulla: preparation, marker
      enzyme studies and phospholipid composition.

PMID- 4371835
TI  - Some factors affecting the valinomycin-induced leak from liposomes.

PMID- 4371836
TI  - The effect of phospholipase on the binding of asialoglycoproteins by rat liver
      plasma membranes.

PMID- 4371837
TI  - Substrate-induced membrane potential changes in the perfused rat liver.

PMID- 4371838
TI  - Biosynthetic pathways and turnover of individual biliary phosphatidylcholines
      during metabolism of (1,1-2H2)ethanol in the rat.

PMID- 4371839
TI  - Biosynthesis of molecular species of phosphatidylcholines in bile, liver and
      plasma of rats given (1,1-2H2)ethanol.

PMID- 4371840
TI  - Mono-acid diacylglycerols in human adipose tissue.

PMID- 4371841
TI  - Lipid components of two different regions of an intestinal epithelial cell
      membrane of mouse.

PMID- 4371842
TI  - The kinetics of NAD-linked isocitrate dehydrogenase from calf heart.

PMID- 4371843
TI  - Protein kinases in Tetrahymena cilia. II. Partial purification and
      characterization of adenosine 3',5'-monophosphate-dependent and guanosine 3',5'
      monophosphate-dependent protein kinases.

PMID- 4371844
TI  - Studies on manganese-substrate complexes of arginine kinase from Panulirus
      longipes.

PMID- 4371845
TI  - Effect of sulfhydryl reagents on the activity of histidinolphosphatase from
      Salmonella typhimurium and bakers' yeast.

PMID- 4371846
TI  - Cyclic nucleotide phosphodiesterase in silkworm: purification and properties.

PMID- 4371847
TI  - Separation of multiple forms of cyclic nucleotide phosphodiesterases from rat
      brain by isoelectrofocusing.

PMID- 4371848
TI  - Identification of the thiol residues involved in modifications of pig heart
      lipoamide dehydrogenase by cupric ion and by iodoacetamide.

PMID- 4371849
TI  - Oxidation of NADH by melanin and melanoproteins.

PMID- 4371850
TI  - Regulation of purine metabolism in Schizosaccharomyces pombe. IV. Variations in
      the stability and kinetic parameters of amidophosphoribosyltransferase depending
      on growth phase and growth conditions.

PMID- 4371851
TI  - A fluorescent probe for the coenzyme-induced structural changes in glyceraldehyde
      3-phosphate dehydrogenase from rabbit muscle.

PMID- 4371852
TI  - EPR studies of nitric oxide complexes of turnip and horse-radish peroxidases.

PMID- 4371853
TI  - Binding of the estradiol receptor from calf uterus to the chromatin: active
      forms.

PMID- 4371854
TI  - Tritium labeling of luteinizing hormone by reductive methylation.

PMID- 4371855
TI  - The apoproteins of various size classes of human chylous fluid lipoproteins.

PMID- 4371856
TI  - Magnetic susceptibility of lacquer tree laccase.

PMID- 4371857
TI  - Multiple molecular forms of phosphoprotein phosphatase. II. Dissociation and
      activation of phosphorylase phosphatase from rabbit skeletal muscle.

PMID- 4371858
TI  - Metabolism of phytane in rats.

PMID- 4371859
TI  - The cleavage of the carbon--cobalt bond in vitamin B12 and coenzyme B12 by
      reduction with electrons in gamma-irradiated frozen solutions.

PMID- 4371860
TI  - The pancreatic beta-cell recognition of insulin secretagogues. XIII. Effects of
      sulphydryl reagents on cyclic AMP.

PMID- 4371861
TI  - Subcellular localization and some properties of the adenylate cyclase activity of
      the yeast, Saccharomyces cerevisiae.

PMID- 4371862
TI  - Cyclic AMP and thyroglobulin biosynthesis in the experimental rat thyroid tumor.

PMID- 4371863
TI  - The isolation and partial characterization of a glycoprotein isolated from human
      gastric aspirates and from extracts of gastric mucosae.

PMID- 4371864
TI  - The effect of isoproterenol and its analogs upon adenosine 3',5'-monophosphate
      and guanosine 3',5'-monophosphate levels in mouse parotid gland in vivo.
      Relationship to the stimulation of DNA synthesis.

PMID- 4371865
TI  - The actions of insulin and glucagon on glucose metabolism and on related enzyme
      activities in the isolated perfused rat liver.

PMID- 4371867
TI  - Glycoprotein biosynthesis in liver mitochondria. II. Mitochondrial localization
      of mannosyltransferase.

PMID- 4371866
TI  - Androgen receptors in rat ventral prostate microsomes.

PMID- 4371869
TI  - The effect of pressure on the phase diagram of mixed dipalmitoyl
      dimyristoylphosphatidylcholine bilayers.

PMID- 4371868
TI  - Cycloheximide inhibition of hypoxanthine transport cultured cells.

PMID- 4371870
TI  - Effect of several "specific" chemical reagents on the Na+, K+ and leakage
      currents in voltage-clamped single nodes of Ranvier.

PMID- 4371871
TI  - Effect of chemical modifiers of passive permeability on the conformation of spin
      labeled erythrocyte membranes.

PMID- 4371872
TI  - Effect of theophylline and Na+ on methionine influx in Na+-depleted intestine.

PMID- 4371873
TI  - Temperature sensitivity of the assembly process of the enveloped bacteriophage
      phi6.

PMID- 4371874
TI  - Properties of the homogeneous main band DNA from the human genome.

PMID- 4371875
TI  - The methylation of transfer RNA in Escherichia coli.

PMID- 4371876
TI  - [Application of the paramagnetic label method to the study of conformational
      changes in DNA during UV-irradiation].

PMID- 4371877
TI  - [New analogs of NAD containing a fluorescent pyridine fragment].

PMID- 4371878
TI  - [Effect of platinum and palladium complexes on the activity of and conformational
      transitions in transport ATPase].

PMID- 4371879
TI  - [Photooxidation reaction of metal complexes of porphyrins at 293 and 77 degrees
      K].

PMID- 4371881
TI  - [Participation of free radicals in oxidative transformation and mechanism of
      action of vitamin D].

PMID- 4371880
TI  - [Cholesterol solubilization by lecithins from normal and neoplastic tissues].

PMID- 4371882
TI  - [Biorhythms. II. Disorders in circadian rhythms of paramagnetic center
      concentrations in animal organs exposed to ionizing radiation].

PMID- 4371884
TI  - Is there a first night effect? (a revisit).

PMID- 4371883
TI  - Longitudinal study of the effects of lithium carbonate on the sleep of
      hospitalized depressed patients.

PMID- 4371885
TI  - Spontaneously recalled verbal material and its linguistic organization in
      relation to different stages of sleep.

PMID- 4371887
TI  - Simplified radioimmunoassay of angiotensin II.

PMID- 4371886
TI  - The intracellular phase of fat absorption.

PMID- 4371888
TI  - Some hydrodynamic and optical properties of polyribonucleotides.

PMID- 4371889
TI  - On site heterogeneity in sturgeon muscle GPDH: a kinetic approach.

PMID- 4371890
TI  - Nucleotide and serotonin metabolism in platelets with defective secondary
      aggregation.

PMID- 4371892
TI  - Isolation of virus from the urine, conjunctiva and throat of smallpox cases.

PMID- 4371893
TI  - Further observations on the virological studies on the epidemic of conjunctivitis
      in Calcutta.

PMID- 4371891
TI  - Criteria for the differentiation of lymphoid cell lines.

PMID- 4371894
TI  - Role of acetylcholine in the mechanism of nervous autoregulation of the heart.

PMID- 4371895
TI  - Role of the limbic structures in the mechanism of action of glucocorticoids and
      estrogens on hypothalamic control of pituitary adrenocorticotropic and
      gonadotropic functions.

PMID- 4371897
TI  - A rare case of hidradenoma papilliferum: report of a case and review of the
      literature.

PMID- 4371896
TI  - The mechanism of action of ACTH on the adrenal cortex.

PMID- 4371898
TI  - Vascular reactivity in spontaneously hypertensive normotensive and hypotensive
      rats.
AB  - 1 Three strains of rats spontaneously hypertensive (HRS), normotensive (NS) and
      hypotensive (HOS), were selected by repeated inbreeding.2 In order to explain the
      different blood pressure levels observed, we have studied their vascular
      reactivity to noradrenaline and angiotensin II. Experiments were performed in
      anaesthetized ganglion-blocked, vagotomized rats.3 The reactivity to
      noradrenaline was significantly higher in HRS than in NS and HOS rats.4 The
      reactivity to angiotensin II appeared identical in the three strains used.

PMID- 4371899
TI  - Effects on plasma and brain tryptophan in the rat of drugs and hormones that
      influence the concentration of unesterified fatty acid in the plasma.
AB  - 1 The effects on tryptophan distribution and metabolism of drugs altering plasma
      unesterified fatty acid (UFA) concentration were investigated in the rat.2 UFA
      and plasma free (i.e. ultrafilterable) tryptophan altered in the same direction.3
      Catecholamines and L-DOPA increased both plasma UFA and free tryptophan. L-DOPA
      also increased brain tryptophan and 5-hydroxyindoleacetic acid (5-HIAA) but
      decreased brain 5-hydroxytryptamine (5-HT).4 Aminophylline increased plasma UFA
      and free tryptophan and also brain tryptophan, 5-HT and 5-HIAA. Food deprivation
      had qualitatively similar effects.5 Insulin decreased plasma UFA and free
      tryptophan in both fed and food-deprived rats. However, while in fed rats these
      changes were associated with small decreases of brain indoles, in food-deprived
      animals small increases occurred.6 Nicotinic acid had only small effects in fed
      rats but it opposed both the UFA and indole changes in food-deprived animals.
      Total plasma tryptophan increased in nicotinic acid treated, food-deprived rats.7
      There was a tendency towards inverse relations between changes of plasma free and
      total tryptophan.8 The results suggest that drugs which influence plasma UFA
      through actions on cyclic AMP thereby alter the binding of tryptophan to plasma
      protein and that this leads to altered distribution and metabolism of tryptophan.

PMID- 4371900
TI  - Mechanism of the pro-inflammatory activity of sympathomimetic amines in thermic
      oedema of the rat paw.
AB  - 1 Thermic oedema induced by heating rat paws at 46.5 degrees C was potentiated by
      local injection of adrenaline, noradrenaline or high doses of isoprenaline. The
      pro-inflammatory effect of sympathomimetic amines was antagonized by
      phenoxybenzamine or phentolamine but not by propranolol.2 The subcutaneous space
      of heated rat paws was perfused with Tyrode solution and the perfusate collected
      and assayed for bradykinin, bradykininogen, kinin-forming activity and kininase
      activity. When adrenaline (0.5 mug/ml) was included in the perfusion fluid,
      kininase activity of the perfusate was increased by 76% and free bradykinin
      reduced by 46%.3 Increased vascular permeability induced by injection of
      bradykinin or kallikrein was reduced by adrenaline or noradrenaline, but
      isoprenaline had no significant effect.4 Pretreatment with soya bean trypsin
      inhibitor (SBTI) or heparin did not antagonize the pro-inflammatory effect of
      adrenaline or thermic oedema per se.5 Potentiation of thermic oedema similar to
      that induced by sympathomimetic amines was obtained by injecting paws with
      vasopressin prior to heating, or by applying a ligature to stop blood flow to the
      paw for the first 15 min of heating.6 Thermistor probes inserted beneath the paw
      skin showed that sympathomimetic amines increased the internal temperature of
      heated paws. This was significant, as small changes in temperature had a marked
      effect on the development of thermic oedema.7 It is suggested that
      sympathomimetic amines potentiate thermic oedema of rat paws heated at 46.5
      degrees C by reducing blood flow to the paw, thereby causing a greater rise in
      paw temperature and consequently greater injury.

PMID- 4371901
TI  - Effect of ethanol on the oxidative metabolism of tryptamine by rat liver
      homogenate.
AB  - 1 The effect of a wide range of ethanol concentrations (v/v) on indoleacetic acid
      (IAA) formation from the oxidative deamination of tryptamine was studied in
      vitro, in rat whole liver homogenate.2 IAA production was inhibited progressively
      by ethanol in concentrations between 0.01% to 0.2%, but the inhibition declined
      when the ethanol concentration was increased further to 6%.3 Ethanol-induced
      inhibition of IAA formation was only partially reversed by excess aldehyde
      dehydrogenase, whereas reductions in IAA formation were completely prevented by
      pyrazole or ethanol (6% and 10%) itself.4 Excess nicotinamide adenine
      dinucleotide failed to alter the inhibitory effect of ethanol and no evidence was
      obtained for inhibition of monoamine oxidase by ethanol or its metabolite,
      acetaldehyde.5 We conclude that ethanol indirectly inhibits IAA production as a
      result of oxidation of ethanol by alcohol dehydrogenase, during which the
      oxidative metabolism of tryptamine is shifted towards the reductive pathway, thus
      favouring the formation of tryptophol in place of IAA.

PMID- 4371902
TI  - Dose-response curves for angiotensin II and synthetic analogues in three types of
      smooth muscle: existence of different forms of receptor sites for angiotensin II.
AB  - 1 The dose-response curves for angiotensin II and four analogues in rat colon and
      uterus, and in rabbit aorta, were obtained.2 The ED(50) values of angiotensin II
      as well as the ED(50)s and intrinsic activities of angiotensin analogues varied
      between the three organs.3 The interaction of two competitive antagonists with
      angiotensin II receptors was also examined. The K(I) values obtained with both
      antagonists on the uterus differed from the values on the other tissues.4 It is
      concluded that angiotensin II receptors may be different in the three organs
      examined.

PMID- 4371903
TI  - Letter: B-lymphocytes as target cells for E.B. virus transformation.

PMID- 4371905
TI  - What could the G.P. treat at home--with proper support?

PMID- 4371904
TI  - Editorial: Screening for hyperlipidaemia in childhood.

PMID- 4371906
TI  - Letter: E.B. virus and treatment of lymphomas.

PMID- 4371907
TI  - Paradoxical sleep: prolonged augmentation following learning.

PMID- 4371908
TI  - [Delimitation of gastric granuloblastoma].

PMID- 4371909
TI  - Renin and hypertension.

PMID- 4371910
TI  - Hypertension: selection of treatment in relation to the mechanisms raising blood
      pressure.

PMID- 4371911
TI  - [Clinical trial of UCB 630].

PMID- 4371912
TI  - Comparative measurements of the crystallinity of callus and compact bone by
      electron spin resonance spectrometry.

PMID- 4371913
TI  - [Metabolism of 6-phosphorylglucose in rats treated with phenobarbital].

PMID- 4371914
TI  - [Acute effect (in 3-6 hours) of a single dose of (plus)-catechin on experimental
      biochemical disturbances of the liver in white rats].

PMID- 4371915
TI  - [Capillary barrier of the mesentery of rats which have received intravascular
      injections of Zajdela's ascitic hepatoma. I. In vivo study of microcirculation].

PMID- 4371916
TI  - [Effect of intravenous injection of beta 1-24 corticotropin on somatotropin
      secretion].

PMID- 4371918
TI  - [Galactosemia: detection of galactokinase deficiency].

PMID- 4371917
TI  - [Quantitative evaluation of steroid extrogens by study of the vaginal epithelium
      thickness and mitotic index in mice].

PMID- 4371920
TI  - [Effect of follicular fluid on the in vitro luteinization of granulosa cells in
      rats].

PMID- 4371919
TI  - [Effect of prostaglandin E 1 on liver cells in histiotypic culture].

PMID- 4371921
TI  - [Ultrastructural histochemical study of lipid inclusions in the adrenal cortex of
      the chick embryo during early states of the development].

PMID- 4371922
TI  - [Properties of Nocardia adenylcyclase].

PMID- 4371923
TI  - Biosynthesis of spin-labelled lipids and their use in the study of biological
      membranes: isolation and characterization of membrane-bound spin-labelled sn-3
      phosphatidic acid-2-3H prepared by enzymatic incorporation of spin-labelled
      stearic acid into sn-glycero-3-phosphate-2-3H.

PMID- 4371924
TI  - Evidence for the biosynthetic difference between isolated mitochondria and
      microsomes from guinea-pig and rat liver regarding lysophosphatidic acid,
      phosphatidic acid, CDP-diglyceride, phosphatidylglycerol, and cardiolipin.

PMID- 4371925
TI  - Lipid and temperature dependence of membrane-bound ATPase activity of
      Acholeplasma laidlawii.

PMID- 4371926
TI  - Isolation of dimethylallylpyrophosphate: umbelliferone dimethylally transferase
      from Ruta graveolens.

PMID- 4371927
TI  - Succinate dehydrogenases of Mucor rouxii and Penicillium duponti.

PMID- 4371928
TI  - Localization of phosphate-independent glutaminase in the brush border of rat
      kidney cortex.

PMID- 4371929
TI  - Time differential in labelling of different monosaccharides into serum
      lipoproteins in rats.

PMID- 4371930
TI  - Mutation test of 2,4,5-trichlorophenoxyacetic acid on Drosophila melanogaster.

PMID- 4371931
TI  - Mixed tumor of the nasal septum.

PMID- 4371932
TI  - Regulation of pancreatic acinar function: effects of cyclic AMP, dibutyryl cyclic
      AMP, and theophylline in vitro.

PMID- 4371933
TI  - Intestinal vasoconstriction following diuretic-induced volume depletion: role of
      angiotensin and vasopressin.

PMID- 4371934
TI  - Stimulation of nerve fiber growth from cultured sympathetic explants.

PMID- 4371935
TI  - The effect of intravenous infusions of angiotensin and noradrenaline on systolic
      blood pressure and critical opening pressure of tail vessels in conscious rats.

PMID- 4371936
TI  - Dantrolene sodium: effects on crustacean muscle.

PMID- 4371937
TI  - Negative cardiac inotropic effects of calcium ion and of N-2
      hydroxyethylpiperazine-N' -2-ethanesulfonic acid (HEPES) buffer at normal and low
      sodium concentration.

PMID- 4371938
TI  - Catecholamine binding and the turnover number of adenylate cyclase.

PMID- 4371939
TI  - Surgical treatment of Crohn's disease.

PMID- 4371940
TI  - Pseudomembranous colitis associated with antibiotic therapy - an emerging entity.
AB  - Two cases of pseudomembranous colitis are presented. The first patient had been
      treated with novobiocin-tetracycline and penicillin, and two weeks later
      developed severe fulminating diarrhea with ascites and bilateral pleural
      effusions which did not respond to intravenous ACTH. Subsequently she underwent
      subtotal colectomy and made a rapid and complete recovery. The second patient
      developed severe diarrhea two weeks after a 10-day course of clindamycin. She was
      treated with intravenous ACTH, oral Lactobacillus and a fecal enema and made a
      complete recovery.These cases reconfirm the importance of antibiotics as
      etiologic agents in this disease. They also stress the classic sigmoidoscopic and
      histologic findings that should facilitate prompt and rapid diagnosis.

PMID- 4371941
TI  - Criteria for the post-hospital adjustment of mental patients in sheltered
      settings.

PMID- 4371942
TI  - A quantitative ultrastructural study of the pleomorphic adenoma (mixed tumor) of
      human minor salivary glands.

PMID- 4371943
TI  - Localized fibrous tumors of pleura: a light and electron microscopic study.

PMID- 4371944
TI  - Cell kinetic studies in patients with small cell carcinoma of the lung.

PMID- 4371945
TI  - Angiolymphoid hyperplasia with eosinophilia in the skin.

PMID- 4371946
TI  - Urinary cholesterol--VI. Its excretion in women with inoperable inflammatory
      carcinoma of the breast.

PMID- 4371947
TI  - Concurrence of carotid body tumor and pheochromocytoma.

PMID- 4371948
TI  - Comparison of daunorubicin (NSC-83142) with adriamycin (NSC-123127) in the
      treatment of late-stage childhood solid tumors.

PMID- 4371950
TI  - Half-life of N-acetylneuraminic acid in plasma membranes of rat liver and Morris
      hepatoma 7777.

PMID- 4371949
TI  - Evaluation of intravenous allopurinol (NSC-1390) in pediatric neoplasia.

PMID- 4371951
TI  - A difference between B10.D2-n and B10.D2-o strains of mice in rates of
      irradiation-induced leukemogenesis.

PMID- 4371952
TI  - Estrogen receptor content and hormone-responsive growth of mouse mammary tumors.

PMID- 4371953
TI  - Dietary effects on stearyl coenzyme A desaturase in Morris hepatomas.

PMID- 4371954
TI  - An ultrastructural study of C-type virion assembly in mouse cells.

PMID- 4371955
TI  - Two forms of repair in the DNA of human cells damaged by chemical carcinogens and
      mutagens.

PMID- 4371956
TI  - Further investigation of a variant of the placental alkaline phosphatase in human
      hepatic carcinoma.

PMID- 4371957
TI  - Tumor induction in the progeny of mice receiving 4-nitroquinoline 1-oxide and N
      methyl-N-nitrosourethan during pregnancy or lactation.

PMID- 4371958
TI  - Demonstration of glucose 6-phosphatase activity in the oval cells of rat liver
      and the significance of the oval cells in azo dye carcinogenesis.

PMID- 4371959
TI  - Alteration of tumor response in rat liver by carbon tetrachloride.

PMID- 4371960
TI  - The effect of benzo(alpha)pyrene on the basal and isoproterenol-stimulated levels
      of cyclic adenosine 3',5'-monophosphate in mouse epidermis.

PMID- 4371961
TI  - Incorporation of precursors and inhibitors of nucleic acid synthesis into
      hepatomas and liver of the rat.

PMID- 4371962
TI  - A leukemic lymphoproliferative diseases in A-J mice following inoculation with
      blood from patients with acute infectious hepatitis.

PMID- 4371963
TI  - Phorbol-12-myristate-13-acetate effect on cyclic adenosine 3',5'-monophosphate
      levels in mouse skin and inhibition of phorbol-myristate-acetate-promoted
      tumorigenesis by theophylline.

PMID- 4371964
TI  - In vitro growth of an attenuated mouse leukemia virus.

PMID- 4371965
TI  - The possible correlation of growth rate and expression of transformation with
      temperature-dependent modification in high-molecular-weight membrane
      glycoproteins in mammalian cells transformed by a wild-type and by a
      thermosensitive mutant of avian sarcoma virus.

PMID- 4371966
TI  - In vivo inhibition of tumor growth by cyclic adenosine 3',5'-monophosphate
      derivatives.

PMID- 4371967
TI  - Enhancement of simian virus 40 transformation and integration by 4-nitroquinoline
      1-oxide.

PMID- 4371968
TI  - Cation preferences for poly(rC)-oligo(dG)-directed DNA synthesis by RNA tumor
      viruses and human milk particulates.

PMID- 4371969
TI  - Periodate oxidation of L-iduronic acid residues in dermatan sulphate.

PMID- 4371970
TI  - Alkaline and smith degradation of oxidized dermatan sulphate-chondroitin sulphate
      copolymers.

PMID- 4371972
TI  - Chemical synthesis of P1-2-acetamido-2-deoxy-alpha-D-glucopyranosyl P2-dolichyl
      pyrophosphate.

PMID- 4371971
TI  - Periodate oxidation, acid hydrolysis, and structure-activity relationships of
      human-pituitary, follicle-stimulating hormone and human chorionic gonadotrophin.

PMID- 4371973
TI  - The attachment of poly(ribitol phosphate) to lipoteichoic acid carrier.

PMID- 4371975
TI  - Immunochemical studies on the specificity of soybean agglutinin.

PMID- 4371974
TI  - A micromethod for the determination of 5-(adenosine 5'-pyrophosphoryl)-D-ribose
      (adenosine diphosphoribose-(5)) in biological extracts.

PMID- 4371976
TI  - Fine structural localization of nucleoside triphosphatase and acid phosphatase
      activity in Trichomonas vaginalis Donne.

PMID- 4371977
TI  - Investigations on turnover of adrenocortical mitochondria. II. Effect of chronic
      treatment with ACTH on the 3H-thymidine incorporation into rat zona fasciculata
      mitochondria.

PMID- 4371978
TI  - Cephalopod integument: the ultrastructure of Kolliker's organs and their
      relationship to setae.

PMID- 4371979
TI  - Freeze-fracture studies on the cockroach hemocyte membrane complex: symmetric and
      asymmetric membrane particle distributions.

PMID- 4371980
TI  - Ultrastructural and cytochemical localization of the storage sites of monoamines
      in the paraventricular organ of Xenopus laevis tadpoles.

PMID- 4371981
TI  - Pigment movements in fish melanophores: morphological and physiolgical studies.
      IV. The effect of cyclic adenosine monophosphate on normal and vinblastine
      treated melanophores.

PMID- 4371982
TI  - Studies on the juxtaglomerular apparatus. III. Quantitative morphology after
      treatment with deoxycorticosterone (DOC).

PMID- 4371983
TI  - The release of secretory products from the corticotrophic cells of Salmo
      gairdneri in vitro.

PMID- 4371984
TI  - Metabolism of cyclic adenosine 3':5'-monophosphate in somatic cell hybrids.

PMID- 4371985
TI  - [Restless leg syndrome. Clinical and polygraphical study].

PMID- 4371986
TI  - Nuclear protein changes during the nitrosamine-induced carcinogenesis of rat
      liver.

PMID- 4371987
TI  - Studies on viomycin. VII. Oxidative modifications of viomycin.

PMID- 4371988
TI  - Studies on peptides. XLV. Synthesis of the bovine type corticotropin-like
      intermediate lobe peptide (CLIP).

PMID- 4371989
TI  - Studies on peptides. XLVI. Synthesis of human type corticotropin-like
      intermediate lobe peptide (CLIP).

PMID- 4371991
TI  - [Phospholine iodide in oculomotor disorders].

PMID- 4371990
TI  - Synthesis of D,L-erythro-sphingomyelins.

PMID- 4371992
TI  - Vascular effects of procaine amide in the dog. Predominance of the inhibitory
      effect on ganglionic transmission.

PMID- 4371993
TI  - Characteristics of hypertension in the black population.

PMID- 4371994
TI  - Adolescent hypertension. II. Characteristics and response to treatment.

PMID- 4371995
TI  - Altered sedimentation behavior and ultrastructure of platelets in hyperlipidemia.

PMID- 4371996
TI  - Asthma due to inhaled chemical agents: ampicillin, benzyl penicillin, 6 amino
      penicillanic acid and related substances.

PMID- 4371997
TI  - Transport of beta-carotene in serum of individuals with carotenemia.

PMID- 4371998
TI  - Development and standardization of radioimmunoassays for prostaglandins E, F, and
      A.

PMID- 4371999
TI  - Isozymes of human alpha-L-fucosidase detectable by starch gel electrophoresis.

PMID- 4372000
TI  - Further characterization of the serum pre-alpha-lipoprotein.

PMID- 4372001
TI  - Control of plasma aldosterone in supine anephric man.

PMID- 4372002
TI  - Evidence for an underlying adrenocortical abnormality in hirsute women.

PMID- 4372003
TI  - [Hormonal actions and cyclic AMP].

PMID- 4372004
TI  - [The pituitary gland and cyclic AMP].

PMID- 4372005
TI  - [The kidney and cyclic AMP].

PMID- 4372006
TI  - [The thyroid gland and cyclic AMP].

PMID- 4372007
TI  - [The adrenal glands and cyclic AMP].

PMID- 4372008
TI  - [Relationship between secretion of ovarian 20-alpha-OH-progesterone and LH and
      dynamics of cyclic AMP].

PMID- 4372009
TI  - [Detection of alpha-fetoprotein by hemagglutination reaction and its clinical
      significance].

PMID- 4372010
TI  - A syndrome of polydactyly-syndactyly and triphalangeal thumbs in three
      generations.

PMID- 4372012
TI  - [Case of polyneuropathy probably caused by prolonged thiophenicol therapy].

PMID- 4372011
TI  - Lp(a) lipoprotein and pre-beta1-lipoprotein in patients with coronary heart
      disease.

PMID- 4372014
TI  - Changes in the fatty acid composition of plasma lipoproteins during
      administration of Intralipid to a patient with essential fatty acid deficiency.

PMID- 4372013
TI  - Aldosterone and its regulation during diuresis in patients with gross congestive
      heart failure.

PMID- 4372015
TI  - [Use of calcitonin in Paget's disease].

PMID- 4372016
TI  - Composition of very low density lipoproteins from cholesterol fed animals.

PMID- 4372017
TI  - Leishmania donovani and L. mexicana: production of the excretion factor.

PMID- 4372018
TI  - Chymotrypsins.

PMID- 4372019
TI  - Eggshell calcification with systemic sarcoidosis.

PMID- 4372020
TI  - Granular cell myoblastoma of the bronchus: a new case, 12-year followup report,
      and review of the literature.

PMID- 4372021
TI  - [Effect of 3',5'-AMP on active transport of organic acid in the proximal tubules
      of isolated frog kidney].

PMID- 4372022
TI  - [A combined stimulation test for the simultaneous analysis of several partial
      functions of the anterior pituitary gland (author's transl)].

PMID- 4372023
TI  - [The latex agglutination-inhibition test: a method for rapid antibody
      determination after enterovirus infection (author's transl)].

PMID- 4372024
TI  - [Letter: Lymphography of the human stomach].

PMID- 4372025
TI  - [Therapy of bronchial asthma].

PMID- 4372026
TI  - [Ultrasonic demonstration of an islet-cell adenoma (author's transl)].

PMID- 4372027
TI  - [Diagnosis of isolated nerve lesions (author's transl)].

PMID- 4372028
TI  - [Metabolic effects of diuretics].

PMID- 4372029
TI  - [Clinicopathological conference XVIII. Persistent hypokalemia, hypertension, skin
      pigmentation and pulmonary infiltrate].

PMID- 4372030
TI  - Uptake of exogenous 3H-1,2-testosterone in the hypothalamus, endocrine glands and
      sex-accessory organs in neonatally castrated and androgenized male rats.

PMID- 4372031
TI  - Correlation between the activities of enzymes involved in glucose oxidation in
      corpus luteum and the concentration of sex steroids in systemic plasma during the
      reproductive cycle of the guinea pig.

PMID- 4372032
TI  - Ontogeny of rat hepatic glucocorticoid receptors.

PMID- 4372033
TI  - Preparation of biologically active 125I-TSH.

PMID- 4372034
TI  - Functional and morphological observations on rat adrenal zona glomerulosa cells
      in monolayer culture.

PMID- 4372035
TI  - The effects of hypothyroidism and 2,4-dinitrophenol on growth hormone synthesis.

PMID- 4372036
TI  - Progesterone "receptor" in human endometrium.

PMID- 4372037
TI  - Maternal and fetal plasma progesterone, cortisol, testosterone and 17beta
      estradiol in preparturient sheep: response to fetal ACTH infusion.

PMID- 4372038
TI  - Interaction of lithium with vasopressin-sensitive cyclic AMP system of human
      renal medulla.

PMID- 4372039
TI  - In vitro testosterone biosynthesis in the human fetal testis. II. Stimulation by
      cyclic AMP and human chorionic gonadotropin (hCG).

PMID- 4372040
TI  - 5Alpha-reduction and binding of testosterone in androgen-dependent and 
      independent mouse mammary tumors.

PMID- 4372041
TI  - Chicken insulin: radioimmunological characterization and enhanced activity in rat
      fat cells and liver plasma membranes.

PMID- 4372042
TI  - Inhibitory and facilitatory hypothalamic areas mediating ACTH release in the cat.

PMID- 4372043
TI  - Stimulation of angiotensinogen release by hemodilution in the dog.

PMID- 4372044
TI  - Multiple sclerosis: reticulum cell sarcoma of the nervous system in a patient
      treated with immunosuppressive drugs.

PMID- 4372045
TI  - Chromosome studies on 14 near-diploid carcinomas of the ovary.

PMID- 4372046
TI  - Changes in cell mediated immune functions by growing tumor.

PMID- 4372047
TI  - Interferon production by leukocytes cultures from neoplastic patients.

PMID- 4372048
TI  - Antibiotic combinations of gram-negative infections in patients with cancer.

PMID- 4372049
TI  - Empirical antibiotic therapy in febrile patients with neutropenia and malignant
      disease.

PMID- 4372050
TI  - Advances in the management of Pseudomonas aeruginosa infections in cancer
      patients.

PMID- 4372051
TI  - Pseudomonas septicemia: incidence, epidemiology, prevention and therapy in
      patients with advanced cancer.

PMID- 4372052
TI  - Immune response to adenovirus 12-induced tumour antigens, as measured in vitro by
      the macrophage migration inhibition test.

PMID- 4372053
TI  - In vivo effect of adenosine 3', 5'-monophosphate on Ehrlich ascites tumour cells.

PMID- 4372054
TI  - Estrogen receptors in human breast cancer.

PMID- 4372055
TI  - Specific estrogen receptor of the DMBA-induced mammary carcinoma of the rat and
      its estrogen-requiring molecular transformation.

PMID- 4372056
TI  - Interaction of activated estradiol-receptor complex and chromatin in isolated
      uterine nuclei.

PMID- 4372057
TI  - Adrenal secretion of estrogens, glucocorticosteroids and mineralocorticosteroids
      in the dog.

PMID- 4372058
TI  - Isolation of a tridecapeptide from Natriuretic fractions of bovine posterior
      pituitary.

PMID- 4372060
TI  - Selective activation of mouse T and B lymphocytes by periodate, galactose oxidase
      and soybean agglutinin.

PMID- 4372059
TI  - Interaction of vasopressins and linear N-terminal ACTH fragments in the induction
      of natriuresis.

PMID- 4372061
TI  - The anti-virus activity of double-stranded RNA in the presence of antibody to
      double-stranded RNA.

PMID- 4372062
TI  - The influence of volume loading on the inotropic effect of Ro 7-2956.

PMID- 4372063
TI  - Antidiuretic hormone and renin in rats with diabetes insipidus.

PMID- 4372064
TI  - Cold potentiation of neuromuscular transmission in the avian biventer cervicis
      muscle.

PMID- 4372065
TI  - Release of prostaglandins from the rabbit renal medulla.

PMID- 4372066
TI  - Effects of droperidol on neuromuscular transmission and muscle membrane.

PMID- 4372067
TI  - [Spontaneous tumors in hamsters].

PMID- 4372068
TI  - Antibody-induced redistribution of normal and tumor associated surface antigens.

PMID- 4372070
TI  - Isolation of Kupffer cell lysosomes, with observations on their chemical and
      enzymic composition.

PMID- 4372069
TI  - Rapid isolation of nucleoli from detergent purified nuclei of various tumor and
      tissue culture cells.

PMID- 4372072
TI  - In vitro phosphorylation of chicken erythrocyte histone by various protein
      kinases: absence of phosphorylation from F1 histone.

PMID- 4372071
TI  - Isolation of temperature-sensitive mutants from murine leukemic cells (L5178Y).

PMID- 4372073
TI  - Influence of cell cycle and cell movement on the distribution of intramembranous
      particles in contact-inhibited and transformed cells.

PMID- 4372074
TI  - Proteases as mitogens. The Effect of trypsin and pronase on mouse and human
      lymphocytes.

PMID- 4372076
TI  - Introduction of nuclei and micronuclei into cells and enucleated cytoplasms by
      Sendai virus induced fusion.

PMID- 4372075
TI  - Complementation in hybrid cells derived from mutagen-induced mouse clones
      deficient in hypoxanthine-guanine phosphoribosyl-transferase activity.

PMID- 4372077
TI  - Relation of activation of neurones in the pons and medulla to brain-stimulation
      reward.

PMID- 4372078
TI  - Cerebellar Purkyne cell responses to inputs from sensorimotor cortex.

PMID- 4372080
TI  - Schistosoma mansoni: penetration apparatus and epidermis of the miracidium.

PMID- 4372079
TI  - Somatotopically organized inputs from fore- and hindlimb areas of sensorimotor
      cortex to cerebellar Purkyne cells.

PMID- 4372081
TI  - Effect of a catatoxic steroid pregnenolone-16alpha-carbonitrile, on rat liver
      microsomal subfractions.

PMID- 4372082
TI  - A comparative study of SV40-transformed fibroblast plasma membrane proteins
      labelled by enzymatic iodination or with trinitrobenzene sulfonate.

PMID- 4372083
TI  - Isolation of rat liver cells containing concanavalin-A receptor sites.

PMID- 4372084
TI  - Hepatic action of vasopressin: lack of a role for adenosine-3',5'-cyclic
      monophosphate.

PMID- 4372085
TI  - Hormone-stimulated cAMP production in human placenta perfused in vitro.

PMID- 4372086
TI  - Glycogen synthetase kinase 2 (GSK 2); the identification of a new protein kinase
      in skeletal muscle.

PMID- 4372087
TI  - Inhibition of lipolysis in bovine adipose tissue by butyrate and beta
      hydroxybutyrate.

PMID- 4372088
TI  - Conformational changes at membranes of target cells induced by the peptide
      hormone angiotensin. A spin label study.

PMID- 4372089
TI  - NAD levels in 3T3 cells during exponential growth and density-dependent
      inhibition of growth.

PMID- 4372090
TI  - Nicotinamide 1, N6-ethenoadenine dinucleotide, a coenzyme for glutamate
      dehydrogenase.

PMID- 4372091
TI  - A receptor for testosterone in mature rat testes.

PMID- 4372093
TI  - The effect of catecholamine analogues upon amylase secretion from the mouse
      parotid gland in vivo:relationship to changes in cyclic AMP and cyclic GMP
      levels.

PMID- 4372092
TI  - The amino acid sequence of cytochrome c from Solanum tuberosum (potato).

PMID- 4372094
TI  - The carbohydrate composition of submitochondrial fractions from rat liver.

PMID- 4372095
TI  - Specific spin-labelling of the energy-coupling system of mitochondria.

PMID- 4372096
TI  - A peptic phosphopeptide from the active site of pea seed nucleoside diphosphate
      kinase.

PMID- 4372097
TI  - Synthesis of cytochrome oxidase components in isolated mitochondria of Neurosora
      crassa.

PMID- 4372098
TI  - Activation of adenyl cyclase in the early phase of germination.

PMID- 4372099
TI  - Transcription of the Col E1 genome in colicinogenic E. coli strains during
      induction with mitomycin C.

PMID- 4372100
TI  - Defective protein phosphorylation in membranes of hereditary spherocytosis
      erythrocytes.

PMID- 4372101
TI  - EPR detection of deuteriochlorophyll cation-radicals arising at its photoreaction
      with quinone at low temperature.

PMID- 4372102
TI  - Energy transduction in photosynthetic bacteria. The nature of cytochrome C
      oxidase in the respiratory chain of Rhodopseudomonas capsulata.

PMID- 4372103
TI  - Reaction of cytochrome C oxidase with CO: involvement of the invisible copper.

PMID- 4372104
TI  - Molecular weight determination of the chymotrypsin-like protease of the larvae of
      the hornet, Vespa orientalis, by affinity labeling of the active center.

PMID- 4372105
TI  - LH-RH-receptor interaction is inhibited by des-His--2-des-Gly--10-LH-RH
      ethylamide.

PMID- 4372107
TI  - Present knowledge of the role of chromium.

PMID- 4372106
TI  - Vitamin D: the vitamin and the hormone.

PMID- 4372109
TI  - Lesions associated with impacted teeth.

PMID- 4372108
TI  - [Mobilization of energy sources and activity of enzymes involved in the
      metabolism of cyclic 3'-5'-AMP during muscular activity in relation to adaptation
      to such activity].

PMID- 4372110
TI  - The nature of pain.

PMID- 4372111
TI  - Xanthomatosis and hyperlipoproteinemia; a review.

PMID- 4372112
TI  - Testosterone-protein binding in cytosol of rat anterior hypophysis in vitro:
      evidence for a specific receptor.

PMID- 4372113
TI  - A developmental study on the capacity of rabbit granulosa cells to respond to
      trophic hormones and secrete progesterone in vitro.

PMID- 4372114
TI  - Development of phosphodiesterase activity in the chick retina.

PMID- 4372115
TI  - Increased hepatic gluconeogenesis without a rise of glucagon secretion in rats
      fed a high fat diet.

PMID- 4372116
TI  - Dietary and drug treatment of hyperlipidemia in diabetes.

PMID- 4372117
TI  - [Angiotensin II: its possible role in homeostasis of extracellar fluid volume].

PMID- 4372118
TI  - Quantitative study on thromboplastin in various strains of Yoshida ascites
      hepatoma cells of rat.

PMID- 4372119
TI  - Inhibitory effect of Capsella bursa-pastoris on hepatocarcino-genesis induced by
      3-methyl-4-(dimethylamino)azobenzene in rats.

PMID- 4372120
TI  - Dual infection of hamsters with Adenovirus type 12 and type 6.

PMID- 4372121
TI  - Selective distribution of the radioactivity in nerve tissues of the mouse after
      intravenous administration of 14C-labeled N-methyl-N-nitrosoguanidine.

PMID- 4372122
TI  - Microsomal acetylesterase activity in tumor-bearing rats.

PMID- 4372123
TI  - Collision tumor of the stomach. Report of two cases.

PMID- 4372124
TI  - Effects of cholera toxin and phosphodiesterase inhibitors on fluid transport and
      cyclic adenosine 3',5'-monophosphate concentrations in rabbit gallbladder.

PMID- 4372125
TI  - Endoscopic retrograde cholangiopancreatography in the diagnosis of jaundice
      associated with ulcerative colitis.

PMID- 4372126
TI  - Cytodiagnosis of pancreatic malignant tumors by aspiration, under direct vision,
      using a duodenal fiberscope.

PMID- 4372127
TI  - [Neonatal jaundice and the differential diagnosis of neonatal hepatosplenomegaly
      (author's transl)].

PMID- 4372128
TI  - Further studies on the hormonal control of melanophores and iridophores isolated
      from bullfrog tadpoles.

PMID- 4372129
TI  - A five-step approach to antimicrobial medication. 2. Urinary tract infections.

PMID- 4372130
TI  - Electron microscopic study on the jejunal mucosa in human cholera.
AB  - Small intestinal mucosa obtained from six fasting patients with cholera by a
      peroral biopsy technique was studied with the electron microscope. The cultures
      of their rectal swabs were all positive for Vibrio cholerae. In the absorptive
      cells, large pseudopod-like cytoplasmic processes with deformed microvilli or
      without microvilli (blebs) projected into the intestinal lumen from the apical
      cell surface, interrupting the microvillous border. In the crypts some of the
      undifferentiated crypt cells possessed pseudopod-like cytoplasmic projections
      which extended into the crypt lumen. The swelling of mitochondria, the
      disappearance of their cristae, an increase in the number of vesicles of the
      Golgi apparatus, and the dilatation and vesiculation of endoplasmic reticulum
      were observed in the epithelial cells. The apical portion of the cells became
      oedematous in some of the epithelial cells. Cytoplasmic fragments enclosed by a
      plasma membrane, desquamated epithelial cells, cytoplasmic organelles, and
      secretory granules were lying free in the intestinal lumen.Marked irregular
      widening of the interepithelial spaces in the jejunal mucoa was observed at the
      midvillous area. Many cystic vacuoles were present in the cytoplasm of epithelial
      cells. The possibility of fluids being transported from blood vessels to
      intestinal lumina through the interepithelial spaces, and the significance of
      these pathological findings in human cholera are discussed in this study.

PMID- 4372131
TI  - Histochemical studies on the mucous membrane of the jejunum after vagotomy and
      pyloromyotomy in white rats.

PMID- 4372132
TI  - Ultrastructure of renal glomerulus under conditions of hypercalcemia induced with
      vitamin D3.

PMID- 4372133
TI  - Comparative studies on the behavior of C cells in the rat thyroid under
      conditions of hypercalcemia induced with vitamin D3 and calcium gluconate.

PMID- 4372134
TI  - Oxidative phosphorylation in a yeast mutant lacking alpha-ketoglutarate
      dehydrogenase activity.

PMID- 4372135
TI  - Recent developments in the chemistry of penicillins.

PMID- 4372136
TI  - Structure, chemistry, and biosynthesis of the melanins.

PMID- 4372137
TI  - [Hormones and behaviour in fishes (author's transl)].

PMID- 4372138
TI  - Interactions of 17 beta-estradiol and L-epinephrine on the rat uterus.

PMID- 4372139
TI  - Study of the effects of morphine on adrenal corticosteroids, ascorbic acid and
      catecholamines in unanaesthetized and anaesthetized cats.

PMID- 4372140
TI  - Molecular and catalytic properties of unspecific carboxylesterases (EC 3-1-1-1).

PMID- 4372141
TI  - [The properties of the coenzyme analogue bis-nicotinamide dinucleotide (author's
      transl)].

PMID- 4372143
TI  - Stereospecificities in the metabolic reactions of the four isomeric sphinganines
      (dihydrosphingosines) in rat liver.

PMID- 4372142
TI  - [Synthetic analogues of corticotropin. Contribution of lysine in position 11 to
      the biological activity (author's transl)].

PMID- 4372145
TI  - Studies on the B-protein of human serum beta-lipoprotein using SDS-polyacrylamide
      gel electrophoresis.

PMID- 4372146
TI  - Magnetic resonance studies on the binding of manganese to D-fructose-1,6
      diphosphate 1-phosphohydrolase (hexose-1,6-diphosphatase).

PMID- 4372144
TI  - [Studies on the lipid content and the activity of some enzymes in the liver and
      kidneys of desert rats (Meriones shawii shawii) (author's transl)].

PMID- 4372147
TI  - Metabolic transformation of colchicine. I. The oxidative formation of products
      from colchicine in the Udenfriend system.

PMID- 4372149
TI  - Sphingosine kinase in blood platelets.

PMID- 4372148
TI  - Different half-lives of nicotinamide and adenine moieties of NAD in HeLa S3
      cultures.

PMID- 4372150
TI  - [Substrate specificity and the stability of a phosphoryl phosphatase from rabbit
      serum].

PMID- 4372151
TI  - Expression of the mitochondria genome in wild type and in extracellular mutants
      of Neurospora crassa.

PMID- 4372152
TI  - The orientation of serologically active phospholipids in mitochondrial membranes,
      I.

PMID- 4372153
TI  - The orientation of serologically active phospholipids in mitochondrial membranes,
      II. Studies in vitro with a complement fixation reaction.

PMID- 4372154
TI  - [Proteolytic cleavage of native lactate dehydrogenase from pig heart. I. Studies
      on the possibility of obtaining enzymatically active cleavage products by the
      action of trypsin (author's transl)].

PMID- 4372155
TI  - Mitochondrial H2O2 formation at site II.

PMID- 4372156
TI  - [Relaxation kinetic study of the association equilibrium of glutamate
      dehydrogenase from beef liver (author's transl)].

PMID- 4372157
TI  - Gangliosides of extraneural organs.

PMID- 4372158
TI  - [Enzyme induction in Streptomyces hydrogenans. III. Incorporation and binding of
      steroids (author's transl)].

PMID- 4372159
TI  - Continuous synthesis of NAD in a nuclear column.

PMID- 4372160
TI  - Studies on ADP-ribose ribosylation in rat liver nuclei.

PMID- 4372161
TI  - Radiographic determination of excessive bone loss in Alaskan Eskimos.

PMID- 4372162
TI  - The distribution of some erythrocyte and serum enzyme group systems in the
      Mahishyas and the Muslims of 24-Parganas, West Bengal.

PMID- 4372164
TI  - Certain biochemical changes in the root meristem cells of Vicia faba treated with
      mitomycin C.

PMID- 4372163
TI  - Metabolism of cholesterol in rats under dietary necrosis.

PMID- 4372165
TI  - A dipole mechanism of nervous transmission.

PMID- 4372166
TI  - Effect of age on the composition of major phospholipids of mycobacteria.

PMID- 4372167
TI  - Antisera to carcinoembryonic antigen: removal of persistant impurities.

PMID- 4372168
TI  - Immunological relationship between antigens induced by leukemia virus & mammary
      tumor virus in an inbred mouse strain.

PMID- 4372169
TI  - Jaagziekte & maedi of sheep & goats transmitted in laboratory animals.

PMID- 4372170
TI  - Stimulation of peripheral blood lymphocytes by herpes simplex virus in vitro.
AB  - A method for stimulating sensitized lymphocytes by inactivated herpes simplex
      virus was established by using cultures of washed whole blood cells. The
      development of the immune response of herpes simplex virus-infected guinea pigs
      was examined at different times in the 4-month period after infection. Humoral
      and cellular immune responses were compared in individual animals by measuring
      lymphocyte stimulation ratios and neutralizing serum antibodies.

PMID- 4372171
TI  - Recurrent cutaneous herpes simplex in hairless mice.
AB  - Passively immunized hairless mice were inoculated cutaneously with herpes simplex
      virus. Thirty-nine days later, when the primary cutaneous lesions had completely
      healed, the mice were treated subcutaneously with prednisone. Within 12 to 30
      days after starting prednisone treatment, herpesvirus was recovered by skin swabs
      from 12 of 71 (17%) of the treated mice. This new model has potential application
      for understanding and treating recurrent cutaneous herpes infections.

PMID- 4372172
TI  - Comparison of the action of Escherichia coli enterotoxin on the thymocyte
      adenylate cyclase-cyclic adenosine monophosphate system to that of cholera toxin
      and prostaglandin E1.
AB  - Mouse thymocytes were used to compare mechanisms by which Vibrio cholerae and
      heat-labile Escherichia coli enterotoxins activate the adenylate cyclase-cyclic
      adenosine monophosphate (AMP) system. Both enterotoxins had their time-delayed
      increase in cyclic AMP neutralized by antisera to V. cholerae or E. coli
      enterotoxin, blocked by low concentrations of ganglioside G(M1), and destroyed by
      prior heating. Enterotoxin activation of adenylate cyclase was similarly
      affected. By contrast, prostaglandin E(1)-mediated increases in cyclic AMP were
      not affected by specific antitoxins or gangliosides. Combination of maximal
      stimulatory doses of both enterotoxins did not produce additive increases in
      cyclic AMP. Wash experiments suggested that both enterotoxins bind rapidly and
      tightly to thymocytes at 37 C. However, lowering the incubation temperature to 8
      C reduced the affinity of E. coli enterotoxin but not cholera toxin for
      thymocytes. Results suggest that heat-labile E. coli enterotoxin and cholera
      enterotoxin may activate the same adenylate cyclase enzyme by similar mechanisms.

PMID- 4372173
TI  - Differentiation of strains of infectious bovine rhinotracheitis virus by
      neutralization kinetics with late 19S rabbit antibodies.
AB  - Two vaccine, two respiratory (infectious bovine rhinotracheitis [IBR]), and two
      genital (infectious pustular vulvovaginitis [IPV]) strains of infectious bovine
      rhinotracheitis virus were compared by neutralization kinetics using late 19S
      antibody (AB). The two vaccine strains were indistinguishable from one another,
      but were neutralized far more rapidly than the other four strains when either
      anti-IBR or anti-IPV 19S AB was used. The two IPV strains were indistinguishable
      from one another, but were neutralized significantly more rapidly than the two
      IBR strains when anti-IBR 19S AB was used. The 2 IBR strains were neutralized at
      a similar rate with the latter globulin preparation. Almost identical results
      were obtained with anti-IPV 19S AB, except that one IPV strain was neutralized at
      a rate similar to the IBR strains. However, when early and late rabbit 7S AB were
      used, IBR strains could not be distinguished from IPV strains by neutralization
      kinetics. Preliminary experiments indicated that both early and late 19S rabbit
      antibodies neutralized the homologous strain more rapidly than the heterologous
      strain, but the difference was more noticeable with late 19S AB. It was also
      determined that neutralization of IBR-IPV virus by specific early and late 19S
      rabbit AB and early 7S rabbit AB was markedly enhanced by guinea pig complement.
      Neutralization of this virus by late 7S AB, however, was only slightly enhanced
      by complement. These results suggest that vaccine strains of IBR-IPV virus may be
      distinguished by neutralization kinetics with late 19S rabbit AB, and that
      genital and respiratory strains may possibly also be distinguishable with some
      19S AB preparations.

PMID- 4372174
TI  - Relationship of Ehrlichia canis-infected mononuclear cells to blood vessels of
      lungs.
AB  - The lung tissue of six dogs with ehrlichiosis and two control dogs was examined
      with the electron microscope. Mononuclear cells containing inclusions (morulae)
      of Ehrlichia canis were adhered at one or more sites to the luminal surfaces of
      endothelial cells of arterioles or capillaries by way of interdigitations or
      areas of adherence, or an endothelial cell-bound mononuclear cell was chained to
      another parasitized or nonparasitized mononuclear cell in the lumen. The
      bifurcation of arterioles was the most common site at which mononuclear cells
      clung to the endothelium. Cell-free bodies (morulae), enclosed by a single
      membrane, were present in the lumens of arterioles. Such cell-free bodies were
      swollen and vesiculated as compared with intracytoplasmic inclusions (morulae) in
      mononuclear cells.

PMID- 4372175
TI  - Equine infectious anemia virus from infected horse serum.
AB  - Equine infectious anemia virus was purified from infected horse serum samples.
      Electron microscope observation on negatively stained preparations of purified
      virus showed roughly spherical particles sized between 100 and 200 nm in
      diameter. In disrupted particles, an envelope was visible but no internal
      structure could be resolved. Since the purified virus fraction had a strong
      antigenic activity to antiserum in immunodiffusion reaction, these particles are
      thought to be the causative virus of equine infectious anemia.

PMID- 4372176
TI  - Comparative studies of the Smith and Raynaud strains of murine cytomegalovirus.
AB  - A number of the biological, biophysical, and immunological parameters of the
      Smith and Raynaud strains of murine cytomegalovirus were compared. The two
      strains were found to be indistinguishable.

PMID- 4372177
TI  - Neutralizing activity in isolated serum antibody fractions from visna-infected
      sheep.
AB  - The neutralization technique was used to detect specific antibodies against visna
      virus in isolated immunoglobulin (Ig) G(1), IgG(2), and IgM fractions of visna
      infected sheep serum. The neutralizing antibodies were present chiefly in the
      IgG(1) class. Low amount of activity was demonstrated in the IgM class, but no
      significant activity was seen in the IgG(2) class.

PMID- 4372179
TI  - Cell-mediated immunity in humans during viral infection: dermal hypersensitivity
      and in vitro lymphocyte proliferation during mild viral respiratory infections.
AB  - In vitro lymphocyte proliferation in response to phytohemagglutinin and
      streptokinase-streptodornase and delayed dermal hypersensitivity to several
      antigens were assessed in patients with mild viral upper respiratory infections.
      The response to phytohemagglutinin in 18 patients was not diminished during the
      viral infection. Deoxyribonucleic acid synthesis induced by streptokinase
      streptodornase remained unaffected by the viral illness in five patients, and
      skin test reactivity was not depressed during the viral infection. Thus, it
      appeared that localized viral upper respiratory infections were not associated
      with suppression of systemic cell-mediated immunity.

PMID- 4372178
TI  - Comparison of antibodies against different viruses in cerebrospinal fluid and
      serum samples from patients with multiple sclerosis.
AB  - The occurrence of a local production in the central nervous system (CNS) of
      antibodies against different selected viruses was analyzed by comparison of
      titers in serum and cerebrospinal fluid samples from groups of 50 patients with
      multiple sclerosis from Finland, Norway, and Sweden. Measles antibodies were
      determined in hemagglutination inhibition, hemolysis inhibition, and nucleocapsid
      complement fixation tests; mumps, parainfluenza virus type 1, and rubella virus
      antibodies were determined in hemagglutination inhibition tests; and herpes
      simplex virus type 1 antibodies were determined in passive hemagglutination
      tests. For reference purposes tests were also made for adenovirus antibodies in
      penton hemagglutination enhancement tests and poliovirus antibodies in
      neutralization enhancement tests. Among the 150 multiple sclerosis patients, a
      local production of antibodies against measles virus was found in the CNS in 57%,
      against rubella virus in 19%, mumps virus in 15%, herpes simplex virus type 1 in
      11%, and parainfluenza virus type 1 (Sendai) in 3%. A local production in the CNS
      of antibodies against any of the viruses studied was found in 71% of multiple
      sclerosis patients. These included 48, 16, and 7% that produced antibodies to
      one, two, and three or more viruses, respectively.

PMID- 4372180
TI  - Virus production and release, cell longevity, and cloning efficiency of chicken
      embryo fibroblasts infected with Rous sarcoma virus.
AB  - Continuous virus production is a characteristic of chicken embryo fibroblasts
      (CEF) infected and transformed by a nondefective Schmidt-Ruppin subgroup A Rous
      sarcoma virus. This virus production has been examined with particular attention
      to the amount of newly budded virus which remained cell-associated, and to the
      amount and degree of viral aggregation at the cell surface and in the fluid
      tissue culture medium. The total biologically active virus associated with a
      Schmidt-Ruppin subgroup A Rous sarcoma virus-infected CEF culture was divided
      almost equally between that portion of virus which was present in the fluid
      medium and that portion which was cell-associated. Various mechanical and
      enzymatic methods were used to remove cell-bound virus and to disperse aggregates
      of virus in the tissue culture medium to assess cell production of virus per hour
      accurately, which was determined as an average of 16.4 focus-forming units per
      cell per hour. With appropriate culture conditions, it was found that Schmidt
      Ruppin subgroup A Rous sarcoma virus-infected and -transformed CEF replicated
      faster, could be passaged more times, and grew to higher cell densities than did
      normal CEF and CEF infected with a subgroup A Rous associated virus. Subgroup A
      Rous sarcoma virus-infected CEF cloned with much lower efficiency than did
      subgroup A Rous associated virus-infected CEF or normal CEF. Experiments
      employing a temperature-sensitive mutant of subgroup A Schmidt-Ruppin Rous
      sarcoma virus- and Rous associated virus-infected CEF indicated that the poor
      cloning efficiency of Schmidt-Ruppin subgroup A Rous sarcoma virus infected cells
      was not due to the constant production of virus but was probably related to some
      property associated with transformation of the cell by Rous sarcoma virus.

PMID- 4372181
TI  - Effect of parainfluenza-3 virus neuraminidase on the structure of the gel phase
      of bovine nasal secretion.
AB  - The gel phase of bovine nasal secretion was separated from the liquid phase and
      exposed to parainfluenza-3 virus or Vibrio cholerae neuraminidase under optimal
      in vitro conditions. N-Acetylneuraminic acid was released from the gel by either
      neuraminidase. The release of N-acetylneuraminic acid was accompanied by a
      decrease in the net negative charge of the gel, as evidenced by free zone
      electrophoresis. Scanning electron microscopy showed that after exposure to
      neuraminidases the regular network structure of the untreated gel attained a
      coarse, irregular structure. Samples of gel incubated with 0.15 M sodium chloride
      under similar conditions did not show changes in the net charge or morphology.

PMID- 4372182
TI  - Pathogenesis of human parainfluenza type 3 virus infection in hamster tracheal
      organ culture.
AB  - Hamster tracheal organ culture was employed as a model for the study of the
      pathogenesis of human parainfluenza type 3 virus infection. It clearly supported
      replication of the virus over a 2-week period of time. Infected tracheal explants
      were examined with light, electron, and immunofluorescence microscopy. They
      exhibited specific cytopathologic alterations including nuclear swelling and
      chromatin margination, multinucleated syncytia and binucleated epithelial cells,
      and fibroblasts and chondrocytes. Focal destruction and denudation of the
      respiratory epithelium occurred in later stages of infection. Virus was detected
      in close association with cilia and was observed budding off the unit membrane of
      epithelial cells.

PMID- 4372183
TI  - Induction of disseminated virulent cytomegalovirus infection by immunosuppression
      of naturally chronically infected wild mice.
AB  - Wild mice immunosuppressed with antithymocytic sera show a high incidence of
      disseminated virulent cytomegalovirus infection.

PMID- 4372184
TI  - The mechanism of the adjuvant effect of Bordetella pertussis: the substance
      responsible for the selective enhancement of IgE antibody production.

PMID- 4372185
TI  - Mast cell degranulation: a comparison of the inhibitory actions of disodium
      cromoglycate, drugs known to influence the level of intracellular cyclic
      nucleotide and diisopropylfluorophosphate (DFP).

PMID- 4372186
TI  - Time course of homocytotropic and passive haemagglutinating antibody synthesis in
      the marsupial Setonix brachyurus (the quokka).

PMID- 4372187
TI  - Arthropod-borne disease as a possible factor limiting the distribution of birds.

PMID- 4372188
TI  - Radioassays for the proteolytic enzyme secreted by living eggs of Schistosoma
      mansoni.

PMID- 4372189
TI  - Polyhydric alcohols: structure-supporting solvents for polypeptides and proteins.

PMID- 4372190
TI  - Some considerations of after-care: problems of therapy, training and
      preceptoring.

PMID- 4372192
TI  - An insoluble structural glycoprotein a major constituent of the zonula Zinni.

PMID- 4372191
TI  - Effects of x-radiation on growth and function of the repair blastema (granulation
      tissue). III. Measurements of pharmacodynamic activity in vitro.

PMID- 4372193
TI  - Antagonism of renal angiographic effects of cadmium by zinc.

PMID- 4372194
TI  - Angiography in hepatic cysts and tumors in the rat.

PMID- 4372195
TI  - Effect of oxathiol on the uptake of absorbed doses from polonium-210 in the rat.

PMID- 4372196
TI  - [Forms of peripheral nerve injuries, their diagnosis and assessment].

PMID- 4372197
TI  - [Surgical treatment of injured peripheral nerves].

PMID- 4372199
TI  - [Ischemic damage of peripheral nerves].

PMID- 4372198
TI  - [Problem of radial lesions in upper arm diaphyseal fractures].

PMID- 4372200
TI  - Familial epilepsy and yellow teeth--a disease of the CNS associated with enamel
      hypoplasia.

PMID- 4372201
TI  - Growth and body proportions in 54 boys and men with Klinefelter's syndrome.

PMID- 4372202
TI  - [Hepatosplenic scintigraphy of liver neoplasms in children].

PMID- 4372203
TI  - On the binding of Schiff's reagent in the PAS reaction: effects of molecular
      configurations in models.

PMID- 4372204
TI  - Organ culture of adult guinea-pig intestine. II. Biochemical and
      ultracytochemical findings.

PMID- 4372206
TI  - Fine structure, origin and fate of extracellular materials in the interspace
      between the presumptive lens and presumptive retina of the chick embryo.

PMID- 4372205
TI  - Fine structure of the pars intermedia in the rhesus monkey, Macaca mulatta.

PMID- 4372207
TI  - The effect of transection of the glossopharyngeal nerve upon the structure,
      cholinesterase activity and innervation of taste buds in rabbits.

PMID- 4372208
TI  - Studies on energy and electron transfer systems in the green photosynthetic
      bacterium Chloropseudomonas ethylica strain 2-K. II. Composition of pigments and
      electron transfer systems.

PMID- 4372209
TI  - The inhibition mechanism of the cytochrome oxidase reaction. V. Quantitative
      analyses of the formation of the kinetically inactive complex of cytochrome
      oxidase with cyanide.

PMID- 4372211
TI  - Adenylate kinase activity. In ciliary axonemes isolated from Tetrahymena
      pyriformis.

PMID- 4372210
TI  - The isolation and characterization of glycopeptides from plasma membranes of an
      ascites hepatoma, AH 66.

PMID- 4372212
TI  - Studies on triglyceride synthesis in lipid micelles from adipose tissue.

PMID- 4372213
TI  - Carboxypeptidase CN. II. Stability and some chemical and kinetic properties.

PMID- 4372214
TI  - The role of direct phosphorylation in the mechanism of adenosine utilization for
      nucleotide synthesis in mouse erythrocytes.

PMID- 4372215
TI  - Inhibition of protein kinase and cyclic AMP phosphodiesterase by eritadenine
      isoamyl ester. A possible mechanism for its biphasic effects on cyclic AMP
      dependent lipolysis, steroidogenesis and amino acid uptake.

PMID- 4372216
TI  - Studies of the insulin-like actions of polyamines on lipid and glucose metabolism
      in adipose tissue cells.

PMID- 4372217
TI  - Pyrophosphate:D-fructose 6-phosphate 1-phosphotransferase. A new enzyme with the
      glycolytic function of 6-phosphofructokinase.

PMID- 4372218
TI  - Cyclic adenosine 3':5'-monophosphate and cyclic guanosine 3':5'-monophosphate
      phosphodiesterase activities are under separate genetic control.

PMID- 4372219
TI  - Cytidine 5'-monophosphosialic acid hydrolase. Subcellular location and
      properties.

PMID- 4372220
TI  - Studies on receptor-mediated activation of adenylyl cyclases. I. Preparation and
      description of general properties of an adenylyl cyclase system in beef renal
      medullary membranes sensitive to neurohypophyseal hormones.

PMID- 4372222
TI  - Studies on receptor-mediated activation of adenylyl cyclases. III. Regulation by
      purine nucleotides of the activation of adenylyl cyclases from target organs for
      prostaglandins, luteinizing hormone, neurohypophyseal hormones and
      catecholamines. Tissue- and hormone-dependent variations.

PMID- 4372221
TI  - Studies on receptor-mediated activation of adenylyl cyclases. II. Nucleotide and
      nucleoside regulation of the activities of the beef renal medullary adenylyl
      cyclase and their stimulation by neurohypophyseal hormones.

PMID- 4372223
TI  - Studies on receptor-mediated activation of adenylyl cyclases. V. Transient
      kinetics of the activation of beef renal medullary adenylyl cyclase by
      neurohypophyseal hormones: estimation of apparent rate constants of the receptor
      hormone interaction.

PMID- 4372224
TI  - Solubilization and purification of a prolactin receptor from the rabbit mammary
      gland.

PMID- 4372225
TI  - Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora.
      I. Purification and molecular properties.

PMID- 4372226
TI  - Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora.
      II. Selective chemical reactivity of amino and sulfhydryl groups.

PMID- 4372228
TI  - Physicochemical properties of the diphosphopyridine nucleotide-specific
      isocitrate dehydrogenase of pig heart.

PMID- 4372227
TI  - Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora.
      III. Isolation and sequences of peptides containing selectively labeled lysine
      and cysteine residues.

PMID- 4372229
TI  - Gonadotropin receptors in rat testes. Interaction of an ethanol-soluble
      testicular factor with human follicle-stimulating hormone and luteinizing
      hormone.

PMID- 4372230
TI  - [The treatment of bell's palsy an urgency? (author's transl)].

PMID- 4372231
TI  - Stability of DTP vaccine.

PMID- 4372232
TI  - Some variables in the plaque assay of poliovirus.

PMID- 4372233
TI  - [Immune response of the rabbit to smallpox vaccines].

PMID- 4372234
TI  - Purification and some properties of formate dehydrogenase.

PMID- 4372235
TI  - Cytochrome c-552 and cytochrome c-554 derived from Nitrosomonas europaea.
      Purification, properties, and their function in hydroxylamine oxidation.

PMID- 4372237
TI  - Effect of glucose and adenosine 3', 5'-cyclic monophosphate on the early
      development of Dictyostelium discoideum.

PMID- 4372236
TI  - Pyrophosphatidic acid. A new phospholipid from cryptococcus neoformans.

PMID- 4372239
TI  - Studies on ESR spectra of chromatophores from Rhodospirillum rubrum.

PMID- 4372238
TI  - Studies on lipolysis in lipid micelles isolated from adipose tissue.

PMID- 4372241
TI  - Erythrophagocytosis by the epithelial cells of the bladder.

PMID- 4372240
TI  - Characterization of the external proteins of hamster fibroblasts.
AB  - The results of metabolic labeling studies and enzymatic treatments followed by
      analysis on polyacrylamide gels show that the external proteins of hamster
      fibroblast cell lines, which have been identified by lactoperoxidase-catalyzed
      iodination, do not contain sulphated mucopolysaccharides or hyaluronic acid and
      are probably unrelated to collagen. Several of the iodinated species comigrate
      with carbohydrate-containing molecules. In particular, the major iodine-labeled
      polypeptide of normal fibroblasts appears to be a glycoprotein. This glycoprotein
      is absent or much reduced in virus-transformed cells, as detected both by
      iodination and by metabolic labeling. We conclude that the major iodinated
      polypeptide is not detected on transformed cells because it is absent rather than
      because it is masked. Approximate molecular weights of the external proteins are
      also reported.

PMID- 4372242
TI  - Influence of alkalinity in thin-layer chromatography systems for the separation
      of impurities in chlorpromazine, promazine and promethazine.

PMID- 4372243
TI  - Pseudohypoaldosteronism: persistence of hyperaldosteronism and evidence for renal
      tubular and intestinal responsiveness to endogenous aldosterone.

PMID- 4372244
TI  - The metabolism of vitamin D3 and 25-hydroxyvitamin D3 in normal and anephric
      humans.

PMID- 4372245
TI  - Plasma 17-hydroxyprogesterone, 21-deoxycortisol and cortisol in congenital
      adrenal hyperplasia.

PMID- 4372246
TI  - Embolization of a mediastinal parathyroid adenoma.

PMID- 4372247
TI  - Severe osteopenia in young adults associated with Cushing's syndrome due to
      micronodular adrenal disease.

PMID- 4372248
TI  - Receptor binding properties of 125I-hFSH prepared by enzymatic iodination.

PMID- 4372249
TI  - Sleep EEG stages and plasma growth hormone concentration in states of endogenous
      and exogenous hypercortisolemia or ACTH elevation.

PMID- 4372250
TI  - Profile of circulating vasoactive substances in hemorrhagic shock and their
      pharmacologic manipulation.
AB  - (a) Hemorrhage in dogs (to 45-50 mm Hg) was associated with a 10-fold increase in
      plasma renin activity (PRA) which remained elevated throughout the time-course of
      shock including the irreversible (decompensation) stage. The presence of
      angiotensin II (AII) in arterial blood was demonstrated by the bloodbathed organ
      technique and confirmed by blockade with specific AII antagonists (cysteine(8)
      AII or isoleucine(8)-AII). The contribution of AII to systemic peripheral
      resistance during hemorrhage shock in dogs was established by administering AII
      antagonists which immediately cause a further fall in blood pressure.(b) Plasma
      catecholamines (CA) steadily increased during hemorrhage and peaked during
      compensation (a 100-fold increase). The CA decreased progressively during
      decompensation.(c) Prostaglandin (PG) E-like material was observed in arterial
      blood for 15-60 min (after hemorrhage); the peak arterial concentration was 2.6
      ng/ml blood. Indomethacin (i.v., before 80% of maximum bleedout): (i) confirmed
      the presence of PGE, (ii) increased blood pressure, and (iii) increased blood
      loss.(d) Thus: peripheral resistance during hemorrhagic shock seems temporally
      correlated with blood CA levels (and not PRA), and the renin-AII system
      contributes to the maintenance of vascular resistance and may markedly decrease
      perfusion of organs, such as kidney; the administration of the proper combination
      of specific antagonists of vasoconstrictor humoral substances may radically
      improve organ perfusion and could contribute to ultimate recovery from
      hemorrhagic shock.

PMID- 4372251
TI  - Thyroid hormone action: in vitro characterization of solubilized nuclear
      receptors from rat liver and cultured GH1 cells.
AB  - We previously reported that putative nuclear receptors for thyroid hormone can be
      demonstrated by incubation of hormone either with intact GH(1) cells, a rat
      pituitary tumor cell line, or with isolated GH(1) cell nuclei and rat liver
      nuclei in vitro. We characterized further the kinetics of triiodothyronine (T3)
      and thyroxine (T4) binding and the biochemical properties of the nuclear receptor
      after extraction to a soluble form with 0.4 M KCl. In vitro binding of [(125)I]T3
      and [(125)I]T4 with GH(1) cell and rat liver nuclear extract was examined at 0
      degrees C and 37 degrees C. Equilibrium was attained within 5 min at 37 degrees C
      and 2 h at 0 degrees C. The binding activity from GH(1) cells was stable for at
      least 1 h at 37 degrees C and 10 days at - 20 degrees C. Chromatography on a weak
      carboxylic acid column and inactivation by trypsin and Pronase, but not by DNase
      or RNase, suggested that the putative receptor was a nonhistone protein. The
      estimated equilibrium dissociation constants (K(d)) for hormone binding to the
      solubilized nuclear binding activity was 1.80 x 10(-10) M (T3) and 1.20 x 10(-9)
      M (T4) for GH(1) cells and 1.57 x 10(-10) M (T3) and 2.0 x 10(-9) M (T4) for rat
      liver. These K(d) values for T3 are virtually identical to those which we
      previously reported with isolated rat liver nuclei and GH(1) cell nuclei in
      vitro. The 10-fold greater affinity for T3 compared to T4 in the nuclear extract
      is also identical to that observed with intact GH(1) cells. In addition, the
      [(125)I]T3 and [(125)I]T4 high-affinity binding in the nuclear extract were
      inhibited by either nonradioactive T3 or T4, which suggests that the binding
      activity in nuclear extract was identical for T3 and T4. In contrast, the binding
      activity for T4 and T3 in GH(1) cell cytosol was markedly different from that
      observed with nuclear extract (K(d) values were 2.87 x 10(-10) M for T4 and 1.13
      x 10(-9) M for T3). Our results indicate that nuclear receptors for T3 and T4 can
      be isolated in a soluble and stable form with no apparent change in hormonal
      affinity. This should allow elucidation of the mechanisms of thyroid hormone
      action at the molecular level.

PMID- 4372252
TI  - Hereditary hemolytic anemia with human erythrocyte pyrimidine 5'-nucleotidase
      deficiency.
AB  - A severe deficiency of a red cell pyrimidine 5'-nucleotidase was found to be
      associated with hereditary hemolytic anemia in four members of three kindreds.
      The syndrome was characterized by marked increases above normal in red cell
      basophilic stippling, total nucleotides, and GSH and by a fairly severe
      deficiency of ribosephosphate pyrophosphokinase (EC 2.7.6.1.). Patient
      erythrocytes uniquely contained large amounts of pyrimidine 5'-ribonucleotides.
      In earlier studies, these were erroneously considered to be adenosine phosphates,
      since all previous investigations of the nucleotides of human red cells and
      reticulocytes have shown 97% or more to contain adenine. Total nucleotides in
      patient cells were present in amounts 3-6 times greater than normal, and
      approximately 80% contained pyrimidine. The ultraviolet spectral curves of
      deproteinized red cell extracts exhibited a shift in maximum absorbance from the
      usual 256-257 nm to approximately 266-270 nm, and absorbance at 250, 270, 280,
      and 290 nm, expressed as a ratio of that at 260 nm, differed greatly from normal.
      The spectral characteristics of extracts provide the basis of a readily performed
      screening procedure, which does not require enzyme assay. The nucleotidase
      activity in deficient red cells assayed less than 14%, and usually less than 10%,
      of normal and much less in terms of reticulocyte-rich blood, where it was
      consistently found to be increased. The enzyme has a pH optimum of 7.5-8.0, is
      inhibited by EDTA, and does not utilize purine 5'-ribonucleotides or beta
      glycerophosphate as substrates. While comparatively few family members have been
      available thus far for study, initial data are compatible with an autosomal,
      recessive mode of transmission of the deficiency. The pyrimidine 5'
      ribonucleotides are presumably derived from RNA degradation and, not being
      diffusible, accumulate when the enzyme catalyzing their dephosphorylation is
      deficient. It is postulated that the prominent basophilic stippling results from
      retarded ribosomal RNA degradation secondary to accumulation of degradation
      products, namely pyrimidine 5'-ribonucleotides. Ribosephosphate pyrophosphokinase
      deficiency is considered to be an epiphenomenon. The mechanism responsible for
      increased red cell GSH is unknown.

PMID- 4372253
TI  - A light and electron microscopic study of the liver in case of erythrohepatic
      protoporphyria and in griseofulvin-induced porphyria in mice.
AB  - The light- and electron-microscopic appearances of a liver biopsy from a case of
      erythrohepatic protoporphyria are compared with the appearances of the liver in
      griseofulvin-induced porphyria in mice. Crystals are present in hepatocytes and
      in the bile secretory pathways in each case. The nature and significance of these
      is discussed.

PMID- 4372254
TI  - Contribution of the fatty acids of three low density serum lipoproteins to bovine
      milk fat.

PMID- 4372255
TI  - Hereditary bovine syndactyly. II. Hyperthermia.

PMID- 4372256
TI  - A test of the salience hypothesis of dream recall.

PMID- 4372257
TI  - Reactions in glass ionomer cements: II. An infrared spectroscopic study.

PMID- 4372258
TI  - Induced collagenolytic activity by electrical stimulation of embryonic
      fibroblasts in tissue culture.

PMID- 4372259
TI  - Collagenolytic activity of human gingival crevice fluid.

PMID- 4372260
TI  - Potassium dependent phosphatase in mitochondria of rat submandibular gland.

PMID- 4372261
TI  - Simulation of the effect of recruitment on loudness relationships in speech.

PMID- 4372262
TI  - Implication of mycotoxins for human health.

PMID- 4372263
TI  - Effects of processing on the amine content of pork bellies.

PMID- 4372264
TI  - Photodecomposition of mirex on silica gel chromatoplates exposed to natural and
      artificial light.

PMID- 4372265
TI  - Electron spin resonance spectroscopy of single crystals of concanavalin A.

PMID- 4372266
TI  - Electron spin resonance spectroscopy of aqueous solutions of concanavalin A.

PMID- 4372267
TI  - Sensitivity of human diploid embryonic lung cells for isolation of ECHO viruses
      from sewage.

PMID- 4372268
TI  - Myxovirus parainfluenzae type 4 A growth in monkey-kidney tissue cultures and
      respiratory epithelium of experimentally infected hamsters.

PMID- 4372269
TI  - Maintenance of latent herpetic infection: an apparent role for anti-viral IgG.

PMID- 4372270
TI  - Modulation of polymorphonuclear leukocyte-mediated antibody-dependent cellular
      cytotoxicity.

PMID- 4372271
TI  - Relative insensitivity of spleen cells to interferon.

PMID- 4372272
TI  - Susceptibility tests of anaerobic bacteria: statistical and clinical
      considerations.

PMID- 4372273
TI  - Cyclophosphamide-potentiated West Nile viral encephalitis: relative influence of
      cellular and humoral factors.

PMID- 4372274
TI  - A comparison of two methods of gentamicin assay: an enzymatic procedure and an
      agar diffusion technique.

PMID- 4372276
TI  - Cytosine arabinoside for localized herpes zoster in patients with cancer: failure
      in a controlled trial.

PMID- 4372275
TI  - Serologic response to varicella-zoster membrane antigens measured by direct
      immunofluorescence.

PMID- 4372277
TI  - Workshop on hospital-associated infections.

PMID- 4372278
TI  - Influenza research in the Soviet Union--1974.

PMID- 4372279
TI  - Letter: Severe combined nephrotoxicity of BL-P1654 and gentamicin.

PMID- 4372280
TI  - [Studies on the titers of hemagglutination inhibition antibody against Japanese
      encephalitis virus and the result of vaccination in the aged].

PMID- 4372281
TI  - [ESR-active (g equals 2.00) substance in biological materials. (Part 1) (author's
      transl)].

PMID- 4372282
TI  - [ESR-active (g equals 2.00) substance in biological materials. (Part 2) (author's
      transl)].

PMID- 4372283
TI  - A hepatocarcinoma with osseous metastases.

PMID- 4372284
TI  - Lipoproteins in a nonrecirculating perfusate of rat liver.
AB  - Rat livers were perfused in a nonrecirculating system for 30-40 min with Krebs
      Ringer bicarbonate-0.1% glucose solution gassed with 95% O(2)-5% CO(2) at 37
      degrees C at a flow rate of 3 ml/g/min. The livers appeared normal as judged by
      O(2) uptake, bile flow, transaminase release, and net protein output (2.5
      mg/g/hr). The perfusate was concentrated by ultrafiltration using Amicon PM-10 or
      PM-30 membranes. The concentrated perfusate was subjected to sequential
      ultracentrifugation at solution densities of 1.006, 1.04, 1.06, and 1.21, and the
      top fractions were analyzed for protein and lipid. The net release of protein in
      the four density classes, suitably corrected, averaged 39, 10, 5, and 20 micro
      g/g/hr. The lipid composition of the perfusate lipoprotein fractions differed
      from that of serum mainly in the high percentage of free cholesterol, reflecting
      the lack of exposure to lecithin:cholesterol acyltransferase. When rat serum was
      fractionated in the same way, most of the lipoprotein in the d 1.006-1.06 range
      had a density greater than 1.04. It was concluded from these experiments that the
      liver secretes very low density lipoprotein (VLDL), high density lipoprotein
      (HDL), and a modified form of VLDL containing less lipid. Comparison of secretion
      rates and serum lipoprotein levels leads to the conclusion that the latter are
      largely determined by catabolic rates. When labeled amino acids were present, the
      perfusate HDL had a higher specific activity than VLDL. Addition of carrier whole
      serum did not alter recovery of labeled lipoproteins, but when these were
      isolated from Golgi membranes after a 40-min perfusion, more than twice as much
      label was recovered in HDL, suggesting the presence of precursors within the
      Golgi. The main advantages of the nonrecirculation perfusion technique are the
      avoidance of catabolic reactions, simplicity, and complete control over the
      composition of the perfusing medium.

PMID- 4372285
TI  - Subcellular localization of hexadecanedioic acid activation in human liver.
AB  - The activation of hexadecanedioic acid has been studied in subcellular fractions
      of human liver. The activation capacity in a total homogenate of human liver was
      found to be 0.5 micro mole/min/g wet wt of tissue, about 10% of that for palmitic
      acid. Hexadecanedioic acid was activated by the mitochondrial and microsomal
      fractions. The mitochondrial enzyme is probably localized outside the inner
      mitochondrial compartment. The subcellular distribution of the hexadecanedioic
      acid activation was almost identical with the distribution of palmitic acid
      activation. Hexadecanedioic and palmitic acids seemed to compete for the same
      enzyme.

PMID- 4372286
TI  - Stimulation of erythroblast maturation in vitro by sphingolipids.
AB  - A lipid factor previously isolated from leukocytes and found to stimulate
      basophilic erythroblast formation in an in vitro system of incubated rabbit bone
      marrow cells has been analyzed by thin-layer chromatography, gas-liquid
      chromatography, and gas-liquid chromatography-mass spectrometry. The biologically
      active components are sphingosine ceramides of tetracosanoic and
      dehydrotetracosanoic acids. Tests of a series of related ceramides show a high
      degree of structural specificity for the C(24)-V-acyl compounds with significant
      but markedly lower activity of the C(22) analog. Commercially available
      sphingomyelin shows activity comparable to that of the tetracosanoic acid
      ceramide. Sphingosine and tetracosanic acid supplied in equimolar amounts have
      negligible activity. The results, in the context of other findings, suggest a
      possible supportive role of plasma ceramides and sphingomyelins in red cell
      maturation.

PMID- 4372287
TI  - Influx of cholesterol into plasma in rabbits with fasting
      hyperbetalipoproteinemia.
AB  - New Zealand white rabbits exhibited as much as a threefold increase in plasma
      cholesterol but no change in hepatic cholesterol when fasted for 7-9 days.
      Agarose electrophoresis and ultracentrifugation of plasma samples showed that
      only low density lipoprotein increased during fasting. Fasting changed the
      composition of the low density lipoprotein by increasing the percentage of
      cholesterol and decreasing the percentage of triglyceride while protein and
      phospholipid remained the same. Rates of cholesterol secretion into plasma,
      measured by Triton WR 1339 injection, and rates of plasma cholesteryl ester
      synthesis, determined by [2-(14)C]mevalonate injection, were similar for fed and
      fasted rabbits. These findings suggest that fasting hypercholesterolemia in
      rabbits did not result from increased production of low density lipoproteins.
      Triton WR 1339 was shown to inhibit plasma cholesterol esterification in vitro.

PMID- 4372288
TI  - Reversible protein kinase activation of hormone-sensitive lipase from chicken
      adipose tissue.
AB  - Hormone-sensitive lipase partially purified from adipose tissue of laying hens
      was markedly activated by cyclic AMP-dependent protein kinase. Activation was
      approximately 4-fold (ranging up to as great as 10-fold) compared with the much
      lower degree of activation obtained with analogous preparations from rat and
      human adipose tissues (59 and 86%, respectively). The partially purified
      preparations contained adequate endogenous protein kinase activity to effect
      complete activation with addition of cyclic AMP, ATP, and Mg(2+). Activation was
      blocked by protein kinase inhibitor (from rabbit skeletal muscle) but could be
      restored fully by addition of excess exogenous protein kinase (from bovine
      skeletal muscle). The fully activated lipase was slowly deactivated by dialysis
      at 4 degrees C and then rapidly and almost fully reactivated by addition of
      cyclic AMP and ATP-Mg(2+). Reactivation was blocked by protein kinase inhibitor.
      This deactivation-reactivation cycle was rapid at 23 degrees C with dialysis
      against charcoal and could be demonstrated repeatedly using a single preparation.
      The reversible deactivation of protein kinase-activated enzyme is presumed to
      reflect the action of a lipase phosphatase. Lipase prepared from tissue
      previously exposed to glucagon yielded a much smaller degree of activation than
      lipase prepared from tissue not exposed to the lipolytic hormone, indicating that
      the physiological hormone-induced activation is probably similar to or identical
      with the protein kinase activation demonstrated in the cell-free preparations.
      Under the conditions of assay used, the partially purified lipase fraction
      contained diglyceride, monoglyceride, and lipoprotein lipase activities. However,
      treatment with cyclic AMP-dependent protein kinase had virtually no effect on
      these lipase activities.

PMID- 4372289
TI  - Analysis of alpha-lipoprotein cholesterol in 50 microl of plasma.
AB  - A micromethod for quantitation of alpha-lipoprotein cholesterol was devised for
      gas-liquid chromatography to minimize plasma sample size and facilitate lipid
      studies using capillary blood from children or small animals. alpha-Lipoprotein
      cholesterol was measured by gas-liquid chromatography in 20 micro l of the
      centrifuged supernate obtained after addition of 5 micro l of mixed heparin
      manganese chloride solution 1:1 (v/v) to 50 micro l of plasma. Comparison of
      venous alpha-lipoprotein cholesterol measured by gas-liquid chromatography with
      venous alpha-lipoprotein cholesterol measured by conventional heparin-manganese
      precipitation and ferric chloride (colorimetric) cholesterol determination gave a
      correlation coefficient of 0.98 for 80 plasma samples. Capillary alpha
      lipoprotein cholesterol and venous alpha-lipoprotein cholesterol were closely
      correlated in 31 patients (r = 0.97).

PMID- 4372290
TI  - Immunopathogenicity and oncogenicity of murine leukemia viruses. I. Induction of
      immunologic disease and lymphoma in (BALB-c times NZB)F1 mice by Scripps leukemia
      virus.
AB  - This report clearly demonstrates that a systemic lupus erythematosus (SLE)-like
      syndrome and lymphoma can be induced in immunologically normal (BALB/c x NZB)F(1)
      mice by infection of neonates with a murine leukemia virus (MuLV) (Scripps
      leukemia virus [SLV] 60A) isolated from NZB lymphoblasts. SLV 60A was titered in
      vitro (XC test) and administered to newborn and adult (BALB/c x NZB)F(1) mice
      over six log(10) dilutions. Propagation of MuLV in the newborn recipients was
      indicated by greatly elevated serum Mu gs-1 levels which were proportional to the
      dose of virus given. The SLE-like syndrome was characterized by antinuclear
      antibodies (ANA) and immune complex-type glomerulonephritis. ANA production was
      related to the dose of virus and reached the highest levels at 8-16 wk. The
      incidence of glomerulonephritis was also correlated with the dose of virus and
      reached nearly 50% in the animals given the highest virus dose. Both titers of
      ANA and incidence of glomerulonephritis were greater in females than in males,
      although the amounts of Mu gs-1 in sera of both sexes were equal. The incidence
      of direct Coombs' positivity was not significantly affected by inoculation of
      this virus. The incidence and time of onset of thymocytic lymphoma were linearly
      related to the amount of virus inoculated. High serum Mu gs-1 levels predicted
      lymphoma development and reflected increases in the amount of infectious virus in
      the spleen. No induction of tumors, autoimmunity, or high serum Mu gs-1 levels
      followed administration of SLV 60A to 6-wk old (BALB/c x NZB)F(1) mice or
      inactivated 60A or active AKR virus to newborns.

PMID- 4372291
TI  - Human T lymphocyte "E" rosette function. I. A process modulated by intracellular
      cyclic AMP.
AB  - The capacity of normal human T lymphocytes to form rosettes with sheep red blood
      cells can be inhibited by drugs or agents which induce elevations in
      intracellular levels of cyclic AMP. The effect is early in the presence of agents
      which elicit rapid elevations in intracellular cyclic AMP (isoproterenol,
      aminophylline) and occurs later in the presence of cholera toxin which induces a
      dalayed increase in endogenous cyclic AMP. Dibutyryl cyclic AMP is inhibitory,
      and the effects of dibutyryl cyclic AMP and the adenyl cyclase stimulators are
      potentiated by inhibition of phosphodiesterase. These data provide substantial
      evidence that elevation of intracellular cyclic AMP diminishes E rosette function
      of lymphocytes.

PMID- 4372292
TI  - Stimulation by endocytosis of the secretion of collagenase and neutral proteinase
      from rabbit synovial fibroblasts.
AB  - Rabbit synovial fibroblasts in monolayer culture secrete a specific collagenase
      and a neutral endopeptidase into their serum-free culture medium. The rate of
      secretion of these two enzymes is increased after the ingestion and storage of
      latex particles within the vacuolar system of the cells. The increased rates of
      secretion of the neutral enzymes are stable for over 2 wk in the absence of a
      further phagocytic bout. In constrast there is little change in the extracellular
      levels of two lysosomal hydrolases, cathepsin D and beta-glucuronidase. The
      increase in the secretory rates for the two neutral enzymes is related to the
      number of latex particles ingested by the cells, and increases of up to 12-fold
      over the nonphagocytosing cultures were observed. A variety of other materials
      including mycostatin particles and dextran sulfate also induced increases in the
      secretion of collagenase. These results are discussed in relation to the turnover
      of connective tissue matrix macromolecules.

PMID- 4372293
TI  - Distribution of fibroblast surface antigen: association with fibrillar structures
      of normal cells and loss upon viral transformation.
AB  - The localization of a cell type-specific, soluble fibroblast surface antigen
      (SFA) was studied by immunofluorescence and by scanning electron microscopy of
      the same cells. The antigen had an uneven distribution forming streaks on chick
      embryo fibroblasts. It was localized to membrane processes and ridges, with a
      diameter of 50-200 nm. The processes extended from the periphery of the cells to
      the substratum or to other cells. Trypsin treatment completely removed detectable
      amounts of SFA. The antigen was detectable within 1 h after trypsin-treated cells
      were reseeded. The reappearance of SFA correlated with the restoration of
      membrane processes. Fibroblasts transformed by Rous sarcoma virus (RSV) showed
      loss of all or most SFA. When normal cells were transformed without
      subcultivation and trypsinization a fibrillar extracellular network of SFA
      remained under the transformed fibroblasts while the cells themselves were
      negative in immunofluorescence. When fibroblasts infected by RSV mutants were
      transferred to nonpermissive temperature for transformation new SFA was detected
      within 2 h. These data lead us to propose that loss of stabilizing and anchoring
      effect of SFA molecules in fibrillar cell surface structures may be critical in
      altered growth control and malignant transformation.

PMID- 4372295
TI  - Identification of intracellular polysaccharide granules in thin sections of
      Nocardia asteroides.

PMID- 4372294
TI  - Active transport of amino acids by membrane vesicles of Thiobacillus
      neapolitanus.

PMID- 4372296
TI  - The properties of the Sendai virus ribonucleoproteins involved in genome
      transcription in infected cells.

PMID- 4372297
TI  - DNA synthesis in resting African green monkey kidney cells infected with
      defective SV 40.

PMID- 4372298
TI  - Structural phosphoproteins associated with ten rhabdoviruses.

PMID- 4372299
TI  - Induction of both thymidine and deoxycytidine kinase activity by herpes viruses.

PMID- 4372300
TI  - Biochemical studies on the herpes simplex virus-specified deoxypyrimidine kinase
      activity.

PMID- 4372301
TI  - Cell interaction with poly(rI)-poly(rC) and interferon induction in chick and
      mouse cells.

PMID- 4372302
TI  - A possible precursor containing RNA of a bovine enterovirus: the provirion 11.

PMID- 4372304
TI  - Renaturation of inactivated interferons: requirement for reduction of a major
      component; lack of requirement for reduction of a minor component.

PMID- 4372303
TI  - The iodination of bovine enterovirus particles.

PMID- 4372305
TI  - Translation of virus mRNA: protein synthesis directed by several virus RNAs in a
      cell-free extract from wheat germ.

PMID- 4372306
TI  - Cell fusion by HeLa cells persistently infected with haemadsorption type 2 virus.

PMID- 4372307
TI  - Absence of glycoproteins in poliovirus particles.

PMID- 4372308
TI  - Location of the origin and terminus of replication in polyoma virus DNA.

PMID- 4372309
TI  - Interferon-sepharose: priming of L cells for induction of interferon by MM virus.

PMID- 4372310
TI  - Enhanced production of human interferon by u.v. irradiated cells.

PMID- 4372311
TI  - Focal necrotic hepatitis in mice as a biological marker for differentiation of
      Herpesvirus hominis type 1 and type 2.

PMID- 4372313
TI  - Comparative production of paramyxoviruses by avian heart cells.

PMID- 4372312
TI  - Dependence of RNA replication on continuous protein synthesis in a temperature
      sensitive mutant of foot-and-mouth disease virus.

PMID- 4372314
TI  - Demonstration of a receptor for IgG in Syrian hamster cells transformed with
      herpes simplex virus.

PMID- 4372315
TI  - Immunofluorescent studies of RD-114 virus replication in cell culture.

PMID- 4372316
TI  - Replication of simian virus 40 in permissive cells: assembly of virus components.

PMID- 4372317
TI  - Infectivity of mengovirus replicative form. Relationship to cellular
      transcription.

PMID- 4372318
TI  - Isolation of herpes simplex virus DNA from virus particles and infected cells by
      electrophoresis in polyacrylamide gels.

PMID- 4372319
TI  - Sequential steps in attachment of human rhinovirus type 2 to HeLa cells.

PMID- 4372320
TI  - Electron microscopic studies of visna virus ribonucleic acid.

PMID- 4372321
TI  - Phospholipid metabolism in experimental allergic encephalomyelitis: activity of
      mitochondrial phospholipase A2 of rat brain towards specifically labelled 1,2
      diacyl-, 1-alk-1'-enyl-2-acyl- and 1-alkyl-2-acyl-sn-glycero-3-phosphorylcholine.

PMID- 4372322
TI  - Myelin proteins from different regions of the central nervous system.

PMID- 4372323
TI  - In vitro Ca2+ dependent proteolysis in brain tissues: a possible source of error
      in transmitter metabolism studies.

PMID- 4372324
TI  - Cyclic nucleotide hydrolysis: some possible natural regulators in retina and rod
      outer segments.

PMID- 4372325
TI  - Na+-K+-activated ATPase and K+-activated p-nitrophenylphosphatase activities: a
      comparison of their regional localizations in the C57 mouse brain.

PMID- 4372326
TI  - Plasma renin and angiotensin II levels in subarachnoid haemorrhage.

PMID- 4372327
TI  - Labeled asialo-human chorionic gonadotropin as a liver-scanning agent.

PMID- 4372328
TI  - Preoperative localization of an insulinoma by external scanning with 131I
      toluidine blue.

PMID- 4372329
TI  - Letter: Improving the 99mTc-phosphate bone scan.

PMID- 4372331
TI  - Extreme dysplasia in renal epithelium of a young woman dying from
      hepatocarcinoma.

PMID- 4372330
TI  - Effect of cellulose and cholesterol on blood and yolk lipids and reproductive
      efficiency of the hen.

PMID- 4372332
TI  - Characterisation of spontaneous and induced epithelial and mesenchymal tumours by
      their enzyme patterns.

PMID- 4372333
TI  - Origin of osmophilic inclusion bodies in type II pneumocytes.

PMID- 4372334
TI  - Cytological studies on the absorptive surfaces of cestodes. VIII.
      Phosphohydrolase activity and cation adsorption in the tegument brush border of
      Hymenolepis diminuta.

PMID- 4372335
TI  - Mesenchymal renal neoplasms of infancy revisited.

PMID- 4372336
TI  - Calcified hepatoblastoma in a newborn.

PMID- 4372337
TI  - Critical evaluation of use of effective protein fractions in developing
      pharmacokinetic models for drug distribution.

PMID- 4372338
TI  - Synthesis and biological evaluation of 2-amino-4-hydroxy-6-hydroxymethylpteridine
      pyrophosphate.

PMID- 4372339
TI  - Release of norepinephrine and dopamine-beta-hydroxylase by nerve stimulation. II.
      Effects of papaverine.

PMID- 4372340
TI  - Ontogenesis of adrenergic and cholinergic neuroeffector transmission in chick
      embryo heart.

PMID- 4372341
TI  - Increased sensitivity of sinoatrial pace-maker to acetylcholine and to
      catecholamines at the onset of autonomic neuroeffector transmission in chick
      embryo heart.

PMID- 4372342
TI  - [Proceedings: Echographic semeiology at 2 Mhz].

PMID- 4372343
TI  - Luteolysis in normal and prostaglandin F2 alpha-treated pseudopregnant rabbits.

PMID- 4372344
TI  - The arterial migration of trophoblast in the uterus of the golden hamster,
      Mesocricetus auratus.

PMID- 4372345
TI  - Growth hormone responses to hypoglycaemia in women with secondary amenorrhoea.

PMID- 4372346
TI  - The stimulation of mouse ovarian follicular growth in vitro by dibutyryl cyclic
      adenosine 3':5' monophosphate.

PMID- 4372348
TI  - Laboratory aids in the diagnosis of gynecologic infections--progress and
      pitfalls.

PMID- 4372347
TI  - Current guidelines for the use of antimicrobial agents.

PMID- 4372349
TI  - Letter: Post-coital estrogen.

PMID- 4372350
TI  - Cycloalkanones. 4. Antifertility activity.

PMID- 4372352
TI  - Potential antifertility agents. 7. Synthesis and biological activities of 2-,3-,
      and 6-alkyl-substituted 4-aryl-2-methylcyclohexanecarboxylic acids.

PMID- 4372351
TI  - Potential antifertility agents. 6. Synthesis and biological activities of optical
      isomers of 4 beta-(p-methozyphenyl)-2 beta-methylcyclohexane-alpha-carboxylic
      acid and related compounds.

PMID- 4372353
TI  - Congenital limb anomalies:frequency and aetiological factors. Data from the
      Edinburgh Register of the Newborn (1964-68).

PMID- 4372354
TI  - Mitochondrial inclusions in fibroblast culture from a patient with beta
      methylcrotonylglycinuria.

PMID- 4372355
TI  - Haemoglobin H disease and beta-thalassaemia. Clinical haematological and
      electrophoretic studies in a family from South Lebanon.

PMID- 4372356
TI  - In vivo synthesis of RNA by vesicular stomatitis virus and its mutants.

PMID- 4372357
TI  - Triplication of a unique genetic segment in a simian virus 40-like virus of human
      origin and evolution of new viral genomes.

PMID- 4372358
TI  - Characterization of a rearrangement in viral DNA: mapping of the circular simian
      virus 40-like DNA containing a triplication of a specific one-third of the viral
      genome.

PMID- 4372359
TI  - Binding of divalent copper ions to aspartic acid residue 52 in hen egg-white
      lysozyme.

PMID- 4372360
TI  - An amber dna mutant of Escherichia coli K12 affecting DNA ligase.

PMID- 4372361
TI  - Phosphorylation of Escherichia coli RNA polymerase by rabbit skeletal muscle
      protein kinase.

PMID- 4372362
TI  - A new class of promoter mutations in the lactose operon of Escherichia coli.

PMID- 4372364
TI  - Oncogenicity of the R-35 rat mammary tumor virus.

PMID- 4372363
TI  - Transfer RNA genes in mitochondrial DNA of grande (wild-type) yeast.

PMID- 4372365
TI  - Prevention of lower limb paralysis by neutralization of type-C RNA virus in wild
      mice.

PMID- 4372366
TI  - Comparative pathology of cells transformed by herpes simplex virus type 1 or type
      2.

PMID- 4372367
TI  - Ultrastructural study of herpes simplex virus infection of mouse cells
      chronically producing Rauscher leukemia virus.

PMID- 4372368
TI  - Protection of mice from malignant tumor implants by enucleated tumor cells.

PMID- 4372369
TI  - Possible gene complementation in in vitro cell lines of Ehrlich ascites tumor
      established by cell fusion with sendai virus.

PMID- 4372370
TI  - Carcinoembryonic antigen and blood group substances in carcinomas of the stomach
      and colon.

PMID- 4372371
TI  - Detection of Epstein-Barr virus-determined intracellular antigens in unfixed
      cells with labeled antibodies.

PMID- 4372372
TI  - Distribution of virus particles and mammary tumor virus antigens in mouse mammary
      tumors, transformed BALB-c mouse kidney cells, and GR ascites leukemia cells.

PMID- 4372373
TI  - Histocompatibility genes (the H-2 complex) and susceptibility to mammary tumor
      virus in mice.

PMID- 4372374
TI  - Relationship between the cellular and viral antigens of a BALB-c myeloma and
      murine leukemia virus.

PMID- 4372375
TI  - Antibodies unrelated to Epstein-Barr virus in human sera which precipitate
      soluble components of cultured lymphoblasts.

PMID- 4372376
TI  - Suppression of the avian sarcoma virus genome in hamster-transformed cells made
      resistant to 8-azaguanine.

PMID- 4372377
TI  - Quantitative studies on the developing vascular system of rat hepatoma.

PMID- 4372378
TI  - Inhibitory effect of polychlorinated biphenyls on liver tumorigenesis in rats
      treated with 3'-methyl-4-dimethylaminoazobenzene, n-2-fluorenylacetamide, and
      diethylnitrosamine.

PMID- 4372379
TI  - Erythroid hypoplasia in cats inoculated with feline leukemia virus.

PMID- 4372380
TI  - Bone lesions in cats with anemia induced by feline leukemia virus.

PMID- 4372381
TI  - Hepatic carcinogenesis of aflatoxin M1 in rainbow trout (Salmo gairdneri) and its
      enchancement by cyclopropene fatty acids.

PMID- 4372382
TI  - Carcinogenic effects of oral diethylstilbestrol on C3H male mice with and without
      the mammary tumor virus.

PMID- 4372383
TI  - Further observations on the production of oncornaviruses by MJY-alpha cell line.

PMID- 4372384
TI  - Effect of metabolic inhibitors on killing of tumor cells by antibody and
      complement.

PMID- 4372385
TI  - Changes in growth control and growth requirements associated with neoplastic
      transformation in vitro.

PMID- 4372386
TI  - Protein modification, metabolic controls, and their significance in
      transformation in eukaryotic cells.

PMID- 4372387
TI  - Rhinovirus RNA polymerase: products and kinetics of appearance in human diploid
      cells.
AB  - The kinetics of appearance of an RNA-dependent RNA polymerase activity obtained
      from human embryo lung cells infected with rhinovirus type 2 have been followed
      by analysis of the RNA synthesized by the polymerase preparation in vitro. Little
      single-stranded RNA was synthesized and the proportion of replicative
      intermediate to replicative form was over threefold greater than obtained in
      vivo. The polymerase activity in vivo declined in the presence of cycloheximide
      showing that continued protein synthesis was necessary to maintain RNA
      replication.

PMID- 4372388
TI  - Chromatographic analyses of isoaccepting tRNAs from avian tumor viruses.
AB  - Low-molecular-weight RNA from transforming viruses (Rous sarcoma virus-Rous
      associated virus 1, Schmidt-Ruppin strain of Rous sarcoma virus, and sarcoma
      B(77)), from nontransforming viruses (Rous-associated virus 1 and sarcoma
      NTB(77)), and from chicken liver, chicken embryo fibroblast, and Rous sarcoma
      virus-Rous-associated virus 1-transformed chicken embryo fibroblast was isolated
      and purified. To determine if there are modified, qualitatively or quantitatively
      different isoaccepting species of tRNA in these avian sarcoma viruses as compared
      with the cell of virus origin, chicken embryo fibroblast or normal chicken liver,
      methionyl-, arginyl-, and lysyl-tRNA (with high amino acid acceptance activity),
      and aspartyl- and glutamyl-tRNA from viral-trans-formed cells (with low viral
      amino acid acceptance activity) were co-chromatographed on reversed phase-5
      chromatography columns, and elution profiles were compared. Although in each case
      the elution profile between a particular viral and host cell tRNA differed
      quantitatively, there was no qualitative difference in the profiles of
      corresponding tRNAs from either transforming or nontransforming viruses examined.
      Minor quantitative differences in the elution profiles might be a reflection of
      the metabolic state of the cells, since all evidence points to acceptor activity
      being of host rather than viral origin. Since, with the exception of selective
      packaging of methionyl-tRNA (IV) species by both transforming and nontransforming
      viruses, no selectivity was found for isoacceptor species of other tRNAs, it
      seems that such preferential packaging of methionyl-tRNA (IV) species has no
      bearing on the event of viral transformation.

PMID- 4372389
TI  - Nature of the scrapie agent: evidence against a viroid.
AB  - The postulated viroid nature of scrapie agent was tested. Since the agent could
      not be recovered after a carefully controlled phenol extraction of infected mouse
      brains, it is suggested that this agent is not a viroid.

PMID- 4372390
TI  - Effect of chemically modified 70S RNA from avian myeloblastosis virus (AMV) upon
      the activity of AMV DNA polymerase.
AB  - Adenine residues of 70S avian myeloblastosis virus (AMV) RNA are modified when
      reacted with chloroacetaldehyde. This modification introduces characteristic
      fluorescent epsilon-adenosine (epsilonA) probes which were used to monitor the
      reaction. Under suitable conditions, modified 70S(epsilonA) RNA was maintained
      intact and was inactive as a template for the AMV DNA polymerase. Furthermore, it
      inhibited the reaction catalyzed by AMV polymerase when 70S RNA was used as
      template-primer and had no effect on the two tested bacterial polymerases.
      Protection against the 70S (epsilonA) RNA inhibition was observed when 70S RNA
      was primed with oligo(dT) indicating preference of the polymerase for the
      oligo(dT) primed regions.

PMID- 4372391
TI  - Infectious rous sarcoma virus and reticuloendotheliosis virus DNAs.
AB  - An efficient and quantitative assay for infectious Rous sarcoma virus and
      reticuloendotheliosis virus DNAs is described. The specific infectivities of
      viral DNA corresponded to one infectious unit per 10(5) to 10(6) viral DNA
      molecules. Infection with viral DNA followed one-hit kinetics. The minimal size
      of infectious Rous sarcoma virus DNA was approximately 6 million daltons, whereas
      the minimal size of infectious reticuloendotheliosis virus DNA was larger, 10 to
      20 million daltons.

PMID- 4372392
TI  - Effect of interferon upon the primary and secondary transcription of vesicular
      stomatitis and influenza viruses.
AB  - The synthesis of viral complementary RNA by vesicular stomatitis virus in
      permissive cells can be distinguished operationally into two phases, primary
      transcription, which can be observed in cycloheximide treated cells, and
      secondary transcription, which represents the further synthesis of viral
      complementary RNA obtained in untreated cells. Pretreatment of mouse L cells or
      chicken embryo fibroblasts with the homologous interferon and, for chicken embryo
      fibroblast cells, poly(rI):poly(rC), inhibits the production of infectious virus
      and reduces the synthesis of viral complementary RNA to levels comparable to that
      obtained during primary transcription. Treatment of mouse L cells with interferon
      plus cycloheximide also gives levels of vesicular stomatitis viral complementary
      RNA synthesis comparable to that observed with the cycloheximide treatment alone.
      Similar results have been obtained for interferontreated cells subsequently
      infected with influenza virus (strain WSN). The results are interpreted as
      indicating that inhibition of virus development by interferon does not act at the
      level of primary transcription but rather at an intermediate step between primary
      and secondary transcription, such as viral protein synthesis.

PMID- 4372393
TI  - Reticuloendotheliosis virus nucleic acid sequences in cellular DNA.
AB  - Reticuloendotheliosis virus 60S RNA labeled with (125)I, or reticuloendotheliosis
      virus complementary DNA labeled with (3)H, were hybridized to DNAs from infected
      chicken and pheasant cells. Most of the sequences of the viral RNA were found in
      the infected cell DNAs. The reticuloendotheliosis viruses, therefore, replicate
      through a DNA intermediate. The same labeled nucleic acids were hybridized to DNA
      of uninfected chicken, pheasant, quail, turkey, and duck. About 10% of the
      sequences of reticuloendotheliosis virus RNA were present in the DNA of
      uninfected chicken, pheasant, quail, and turkey. None were detected in DNA of
      duck. The specificity of the hybridization was shown by competition between
      unlabeled and (125)I-labeled viral RNAs and by determination of melting
      temperatures. In contrast, (125)I-labeled RNA of Rous-associated virus-O, an
      avian leukosis-sarcoma virus, hybridized 55% to DNA of uninfected chicken, 20% to
      DNA of uninfected pheasant, 15% to DNA of uninfected quail, 10% to DNA of
      uninfected turkey, and less than 1% to DNA of uninfected duck.

PMID- 4372394
TI  - Expression of the viral thymidine kinase gene in herpes simplex virus-transformed
      L cells.
AB  - In these studies, the expression of thymidine kinase (TK) in normal and herpes
      simplex virus (HSV)-transformed L cells has been compared. In asynchronously
      dividing cultures of L cells, the TK activity rose and declined rapidly and
      coordinately with DNA synthesis. When net cell increase stopped, TK activity was
      at a minimum. In contrast, TK activity of HSV-transformed cells remained at a
      minimum during rapid DNA synthesis and gradually increased as the rate of DNA
      synthesis decreased. When net cell increase stopped, TK activity was at a
      maximum. In synchronous cultures of L cells, TK activity rose and fell
      coordinately with the rate of DNA synthesis. In synchronous cultures of HSV
      transformed cells, no increase in TK activity was observed during the period of
      rapid DNA synthesis, i.e., the S phase. These findings indicated that the viral
      TK gene in HSV-transformed cells was not placed under the control of the cellular
      mechanisms which normally modulate the host cell TK gene. Lytic infection of HSV
      transformed cells with a TK(-) mutant of HSV-1 induced a four-to fivefold
      increase in viral TK. The TK of HSV-1 was induced in the HSV-1-transformed cells
      and HSV-2 in the HSV-2-transformed cells by this TK(-) mutant. The same infection
      of normal L cells decreased the cellular TK activity by 80%. This stimulation,
      rather than inhibition, suggest that the viral gene in HSV-transformed cells
      retain some of its original viral characteristics.

PMID- 4372395
TI  - Envelope proteins of vesicular stomatitis virus: effect of temperature-sensitive
      mutations in complementation groups III and V.
AB  - All five major viral proteins were synthesized in chicken embryo cells infected
      with vesicular stomatitis virus temperature-sensitive (ts) mutants of
      complementation groups III and V and maintained at the nonpermissive temperature.
      The distribution of these proteins among cytoplasmic cellular fractions separated
      on discontinuous sucrose gradients was identical for wild-type and tsIII-infected
      cells. Strikingly different patterns were observed for the G protein in gradients
      from cells infected by tsV mutants; very little, if any, G protein was found in
      the lightest fraction. Pulse and chase experiments with wild-type, virus-infected
      cells showed that protein G moves from the heaviest to the lightest fraction
      before being incorporated into the virion. After shift down to the permissive
      temperature (30 C), G protein synthesized at 39.6 C in tsV-infected cells became
      associated with the lightest cellular fraction and later with the released
      virions. In contrast, M protein, synthesized at 39.6 C in tsIII-infected cells,
      was not incorporated into the virions after shift down. These data strongly
      suggest, first, that M protein is encoded by the vesicular stomatitis gene III,
      and second, that incorporation of G protein in the lightest cellular fraction is
      a necessary step of vesicular stomatitis maturation. This step is impaired by tsV
      mutations.

PMID- 4372396
TI  - Effects of actinomycin D on the cytopathology induced by poliovirus in HEp-2
      cells.
AB  - One possible mechanism of virus-induced cell damage is that the redistributed
      (released) lysosomal enzymes produce the cytopathic effect during cytolytic types
      of infections such as poliovirus in HEp-2 cells. To determine if the lysosomal
      enzyme redistribution and cell damage are host-cell directed, we studied
      sensitivity of these events to the action of actinomycin D. By the use of
      actinomycin D at concentrations producing the least toxicity but maximal
      effectiveness in shuting down cell RNA synthesis, it was shown that the
      cytopathic effect and enzyme redistribution were not inhibited and, therefore,
      not directly controlled and induced by the cell genome in response to the virus
      infection. Evaluation of cytopathic effect by a phase contrast microscopy method
      detected changes earlier than the erythrocin B uptake method.

PMID- 4372397
TI  - Analysis of endonuclease R-EcoRI fragments of DNA from lambdoid bacteriophages
      and other viruses by agarose-gel electrophoresis.
AB  - By means of agarose-gel electrophoresis, endonuclease R.EcoRI-generated fragments
      of DNA from various viruses were separated, their molecular weights were
      determined, and complete or partial fragment maps for lambda, phi80, and hybrid
      phages were constructed.

PMID- 4372398
TI  - Proteolytic cleavage of subunits of the nucleocapsid of the paramyxovirus simian
      virus 5.
AB  - The protein subunits of the nucleocapsid of the parainfluenza virus simian virus
      5 isolated from infected cells after dispersion with trypsin, chymotrypsin, or
      ficin are cleaved proteolytically. The molecular weights of the subunits which
      result from cleavage depend on the enzyme used, but are around 43,000, compared
      to the native subunit of 61,000. In most instances cleavage of the subunit
      appears to be due to the protease used to disperse the cell, and follows cell
      disruption. Nucleocapsids composed of native, uncleaved subunits can frequently
      be obtained from infected cells dispersed without a proteolytic enzyme; however,
      cleavage occasionally occurs even under those conditions, indicating that
      cellular proteases can at times cleave this protein. Nucleocapsids containing
      uncleaved subunits can be isolated from cells persistently infected with simian
      virus 5, indicating that persistent infection is not invariably associated with
      intracellular cleavage of this protein. Nucleocapsids composed of native subunits
      are hydrophobic, whereas those composed of the cleaved subunit can be dispersed
      in aqueous solution. It is suggested that the portion of the molecule removed by
      cleavage may be responsible for a specific interaction during virus assembly
      between the nucleocapsid and those areas of plasma membrane which contain the non
      glycosylated viral membrane protein, which is also hydrophobic. An amino acid
      analysis of native and cleaved subunits has been done. The portion of the subunit
      removed by cleavage does not have a high proportion of hydrophobic residues,
      suggesting that those present are arranged together to form a hydrophobic domain.
      The N termini of both the native and cleaved subunits are blocked. This suggests
      that the portion of the molecule which is externally disposed and removed by
      cleavage contains the C terminus, and the cleaved subunit which reacts with the
      viral RNA contains the N terminus.

PMID- 4372399
TI  - Structure of the mouse mammary tumor virus: characterization of bald particles.
AB  - The polypeptide, antigenic, and morphological structure of the mouse mammary
      tumor virus was studied following protease digestion of intact virions. Intact,
      untreated virions (rho = 1.17 g/ml) had characteristic envelope spikes, five
      major polypeptides, and were precipitated by antisera against gp52. Two of the
      major polypeptides, with molecular weights of 52,000 (gp52) and 36,000 (gp36),
      had carbohydrate moieties. Protease treatment resulted in spikeless, "bald"
      particles (rho = 1.14 g/ml), which had altered surface antigenicity and which
      contained neither gp52 nor gp36. These data indicated that gp52 and gp36 were on
      the viral envelope. Bald particles retained a 28,000 dalton polypeptide (p28)
      which was proposed as the major internal polypeptide.

PMID- 4372400
TI  - Hemagglutination-inhibition: rapid assay for neuraminic acid-containing viruses.
AB  - Influenza virus particles bind rapidly to vesicular stomatitis, Sindbis, or
      Rauscher murine leukemia virus particles, forming mixed aggregates demonstrable
      by electron microscopy. The normal hemagglutinating property of influenza virus
      is inhibited by these viruses, providing a rapid quantitative assay. Prior
      treatment with neuraminidase blocks the ability of other viruses to inhibit
      influenza virus hemagglutination.

PMID- 4372401
TI  - Characterization of polyoma DNA-protein complexes. I. Electrophoretic
      identification of the proteins in a nucleoprotein complex isolated from polyoma
      infected cells.
AB  - A study was undertaken to examine polyoma DNA-protein complexes. A biophysical
      characterization of the complexes was made, and the proteins found in such
      complexes were identified by sodium dodecyl sulfate-polyacrylamide gel
      electrophoresis. A comparison was made between a 52S nucleoprotein complex
      isolated from nuclei of 26-h polyoma-infected cells and a 28S virion core complex
      ejected out of mature virus particles. It was found that both complexes were
      reduced to a 20S viral DNA component plus free protein after incubation in 1 M
      NaCl or Sarkosyl. Treatment of the complexes with either Pronase or 0.5 M NaCl
      resulted in only partial removal of proteins from the viral DNA. After fixation
      in formaldehyde, the 52S nucleoprotein complex had a buoyant density of 1.45
      g/cm(3), and the virion core complex had a buoyant density of 1.59 g/cm(3).
      Sodium dodecyl sulfate-polyacrylamide gel profiles of purified polyoma virion
      proteins, used as a reference marker, demonstrated three capsid proteins, V1 to
      V3, as well as four histones, V4 to V7, which constituted about 7% of the total
      virion protein. Electrophoretic analysis of the proteins comprising the 52S
      nucleoprotein complex revealed that the same seven proteins present in the mature
      virion were also found in this complex. However, the ratios of the proteins in
      the complex were quite different from that of the mature virion, with the four
      histones comprising 48% of the total complex protein. A pulse-chase experiment of
      the nucleoprotein complex demonstrated that the 26-h complex was chased into
      mature virions.

PMID- 4372403
TI  - Nucleic acid homology of murine type-C viral genes.
AB  - The nucleic acid sequence homology between various murine, endogenous type-C
      viruses (three host range classes of BALB/c virus, the AT-124 virus, and the CCL
      52 virus) and two laboratory strains of murine leukemia virus (Rauscher and
      Kirsten) was determined by DNA:RNA hybridization. The viral sequences exhibit
      varying degrees of partial homology. DNA:DNA hybridizations were performed
      between [(3)H]DNA probes prepared from N- and X-tropic BALB/c endogenous viruses
      and cellular DNAs from BALB/c, NIH Swiss, and AKR inbred mouse strains as well as
      from California feral mice and the Asian mouse subspecies Mus musculus molossinus
      and M. musculus castaneus. All of these strains of mice are shown to possess
      multiple (six to seven per haploid genome), partially related copies of type-C
      virogenes in their DNAs. Thermal melting profiles of the DNA:RNA and DNA:DNA
      hybrids suggest that the partial homology of the viral nucleic acid sequences is
      the result of base alterations throughout the viral genomes, rather than the loss
      of discrete segments of viral sequences.

PMID- 4372402
TI  - Molecular weight of two oncornavirus genomes: derivation from particle molecular
      weights and RNA content.
AB  - Sedimentation analysis and intensity fluctuation spectroscopy have been used in
      conjunction with the Svedberg equation to determine the particle molecular
      weights of Rous sarcoma virus (Prague strain) and avian myeloblastosis virus (BAI
      strain). The molecular weights of these two viruses are (294 +/- 20) x 10(6) and
      (256 +/- 18) x 10(6), respectively. Values for the molecular weight of the RNA
      contained in each particle have been calculated as (5.58 +/- 0.5) x 10(6) and
      (5.88 +/- 0.5) x 10(6). Since the proportion of the viral RNA represented by 4 to
      7S low-molecular-weight material is known, the molecular weight of the 60 to 70S
      genomes may be calculated to lie in the range (3.8 +/- 0.3 to 4.8 +/- 0.4) x
      10(6) for both particles. These estimates for the molecular weight of the 60 to
      70S genome are much lower than previous estimates and fall within the range of
      current estimates of the size of a single 35S subunit. The implications of this
      finding are discussed in terms of current theories for the structure of the
      genome of RNA tumor viruses.

PMID- 4372404
TI  - Isolation and characterization of revertant cell lines. VI. Susceptibility of
      revertants to retransformation by simian virus 40 and murine sarcoma virus.
AB  - The susceptibility of two classes of revertants of Simian virus 40 (SV40)
      transformed 3T3 cells to retransformation by SV40 or murine sarcoma virus (MSV)
      was studied. Both serum-sensitive and density-sensitive revertants are not
      retransformable by SV40. MSV can transform both types of revertants. The MSV
      transformed revertants grow to high cell densities and form colonies when
      suspended in semi-solid methylcellulose medium, but are unable to grow in 1% calf
      serum. The MSV-transformed revertants produce infectious MSV and murine leukemia
      virus and possess the same number of chromosomes as the untransformed revertants.

PMID- 4372405
TI  - Avian tumor virus proteins and RNA in uninfected chicken embryo cells.
AB  - The content of proteins P19 and P15 (mol wt 19,000 and 15,000, respectively) of
      avian leukovirus in various types of uninfected chicken embryos has been
      determined by radioimmunoassay. All chicken embryos examined, including embryos
      which have thus far been classified as group specific (gs) antigen negative by
      complement fixation tests, contained these viral proteins as well as P27 as
      previously reported. The embryos known as "gs antigen-positive" type contained
      about five times as much of these viral proteins as did the "gs antigen-negative"
      type. The ratio of the three viral proteins was similar for all types of embryos,
      suggesting that the genes for these proteins are coordinately controlled. In
      contrast to the relatively high levels of viral internal proteins in gs antigen
      negative cells, the amounts of virus-specific RNA detectable by molecular
      hybridization were extremely low. The levels of helper activity, which presumably
      reflect the level of viral envelope glycoprotein, were also generally low or
      undetectable in these cells. Thus, the expression of the gene for envelope
      glycoprotein does not appear to be controlled coordinately with the genes for
      viral internal proteins.

PMID- 4372406
TI  - Levels of rat cellular RNA homologous to either Kirsten sarcoma virus or rat type
      C virus in cell lines derived from Osborne-Mendel rats.
AB  - DNA transcripts from V-NRK and RT21c rat type-C viruses were found to differ in
      their sequence homology to Kirsten and Harvey sarcoma viruses. V-NRK DNA
      transcripts consistently had homology to Kirsten and Harvey sarcoma virus,
      whereas RT21c DNA transcripts did not. To explain the differences, the nucleic
      acids and structural proteins of the two type-C viruses, released from each of
      two cell lines derived from Osborne-Mendel rats, were analyzed by molecular
      hybridization and competition radioimmunoassays. The p30 and p12 structural
      proteins of the two viruses were found to be highly related immunologically. In
      the V-NRK virus preparation, two sets of distinct RNA sequences were found in
      approximately equal amounts. One set is homologous to Ki-SV, and the other
      homologous to RT21c. In contrast, the RT21c virus preparation was found to
      contain a different ratio of these sequences. In this case the RT21c-like RNA
      sequences are present in 100-fold excess as compared to the additional Ki-SV
      specific sequences. Both NRK and RT21c cells contain in their DNA the full
      complement of Ki-SV homologous sequences, but NRK cells express much higher
      levels of these Ki-SV sequences in their RNA. These additional sequences, not
      homologous to RT21c, which are detected in uninfected NRK cellular RNA or V-NRK
      rat virus, could also be detected in the 60-70S RNA from a Moloney mouse type-C
      virus released from the NRK cells infected with the Moloney type-C virus. The
      results suggest that type-C viruses released from NRK cells incorporate species
      of RNA present in NRK cells which are homologous to Kirsten and Harvey sarcoma
      viruses. Either these sequences are of cellular origin, or rat cells contain two
      endogenous viruses with completely distinct nucleic acid sequences.

PMID- 4372407
TI  - Extent of double strandedness in avian myeloblastosis virus RNA.
AB  - The extent of double strandedness of avian myeloblastosis virus 70S RNA has been
      determined from fluorescence measurements of the intercalation of ethidium
      bromide. We have shown that 50% of the nucleotides of 70S RNA in solution are in
      a stable helical configuration. This value does not include small helical regions
      that are too unstable to permit intercalation of the dye. The avian
      myeloblastosis virus RNA as it exists within the virion has the same degree of
      helicity as the free 70S RNA. Heating the free 70S RNA to 55 or 70 C, followed by
      cooling, does not measurably change the degree of helicity; the subunits
      therefore have as much helicity as the parent molecule.

PMID- 4372408
TI  - Mechanistic independence of avian myeloblastosis virus DNA polymerase and
      ribonuclease H.
AB  - Differential inhibition conditions were established for the DNA polymerase and
      RNase H activities of avian myeloblastosis virus (AMV) with ether-disrupted AMV
      and a purified enzyme preparation. The RNase H activity of ether-disrupted AMV
      with (rA)(n).(dT)(n) and (rA)(n).(dT)(11) as substrates was inhibited 80 to 100%
      by preincubation with NaF at a final reaction concentration of 27 to 30 mM. Under
      these conditions, the DNA polymerase activity was inhibited only 0 to 20%.
      Similar inhibitions were found with exogenous Rous sarcoma virus 35S and 70S
      RNA.DNA hybrid and phiX174 DNA.RNA hybrid as substrates. Studies were also
      performed with a purified enzyme preparation, in which the two activities
      essentially co-purified. The RNase H activity was inhibited >80% by 150 mM KCl
      with three different hybrid substrates, whereas the DNA polymerase activity was
      uninhibited. The DNA polymerase was completely inactivated by heat denaturation
      at 41 C or by omission of the deoxytriphosphates from the reaction mixture; the
      RNase H remained active. These differential inhibition conditions were used to
      compare the size of the DNA product synthesized with and without simultaneous
      RNase H action and to examine the effect of inhibition of the DNA polymerase on
      the size of the RNase H products. The size of the products of one activity was
      not affected by inhibition of the other activity. These results suggest that the
      AMV DNA polymerase and RNase H are not coupled mechanistically.

PMID- 4372409
TI  - Properties and location of poly(A) in Rous sarcoma virus RNA.
AB  - The poly(A) sequence of 30 to 40S Rous sarcoma virus RNA, prepared by digestion
      of the RNA with RNase T(1), showed a rather homogenous electrophoretic
      distribution in formamide-polyacrylamide gels. Its size was estimated to be about
      200 AMP residues. The poly(A) appears to be located at or near the 3' end of the
      30 to 40S RNA because: (i) it contained one adenosine per 180 AMP residues, and
      because (ii) incubation of 30 to 40S RNA with bacterial RNase H in the presence
      of poly(dT) removed its poly(A) without significantly affecting its hydrodynamic
      or electrophoretic properties in denaturing solvents. The viral 60 to 70S RNA
      complex was found to consist of 30 to 40S subunits both with (65%) and without
      (approximately 30%) poly(A). The heteropolymeric sequences of these two species
      of 30 to 40S subunits have the same RNase T(1)-resistant oligonucleotide
      composition. Some, perhaps all, RNase T(1)-resistant oligonucleotides of 30 to
      40S Rous sarcoma virus RNA appear to have a unique location relative to the
      poly(A) sequence, because the complexity of poly(A)-tagged fragments of 30 to 40S
      RNA decreased with decreasing size of the fragment. Two RNase T(1)-resistant
      oligonucleotides which distinguish sarcoma virus Prague B RNA from that of a
      transformation-defective deletion mutant of the same virus appear to be
      associated with an 11S poly(A)-tagged fragment of Prague B RNA. Thus RNA
      sequences concerned with cell transformation seem to be located within 5 to 10%
      of the 3' terminus of Prague B RNA.

PMID- 4372410
TI  - Simian virus 40-host cell interactions. II. Cytoplasmic and nucleolar
      accumulation of simian virus 40 virion protein.
AB  - We have used immunofluorescence in parallel with transmission and scanning
      electron microscopy to characterize the unusual cytoplasmic and nucleolar
      accumulation of Simian virus 40 (SV40) virion protein (C antigen) at restrictive
      temperatures (39 to 41 C) in monkey cells infected with a temperature-sensitive
      mutant of SV40 defective in virion assembly, tsB11. Cytoplasmic and nucleolar
      accumulation of C antigen did not occur in wild-type-infected cells at any
      temperature. Wild-type- and tsBll-infected cells were not distinguishable at 33 C
      by immunofluorescence or electron microscopy. Temperature-shift experiments using
      metabolic inhibitors of DNA (cytosine arabinonucleoside, 20 mug/ml), RNA
      (actinomycin D, 5 mug/ml), and protein synthesis (cycloheximide, 2 x 10(-4) to 10
      x 10(-4) M) were used to investigate the requirements for ongoing DNA, RNA, and
      protein synthesis in the distribution of virion protein between the nucleus,
      nucleolus, and cytoplasm. The transport of C antigen from the nucleolus and
      cytoplasm into the nucleus was complete after a temperature shift-down (41 and 39
      to 33 C). Limited virus particle formation occurred after the shift-down in the
      presence of actinomycin D and cycloheximide, indicating some of the 39 to 41 C
      synthesized virion protein could be used for capsid assembly at 33 C in the
      absence of further virion protein synthesis. Nucleolar and cytoplasmic
      accumulations of C antigen occurred in the absence of drugs after a shift-up (33
      to 39 C and 41 C) indicating a continuous requirement for the tsB11 mutant
      function. Furthermore, the virion protein synthesized at 33 C remained confined
      to the nucleus when the cells were shifted to 39 and 41 C in the presence of
      actinomycin D or cycloheximide. In the presence of cytosine arabinonucleoside,
      however, the virion protein accumulated in large aggregates in the nucleus and
      nucleolus after the shift-up, but did not migrate into the cytoplasm as it did in
      drug-free tsB11-infected control cells. Colchicine (10(-3) M) had no effect on
      the abnormal accumulation of C antigen during shift-up or shift-down experiments
      suggesting that microtubular transport plays little if any role in the abnormal
      transport of tsB11 virion protein from cytoplasm to nucleus. Although virus
      particles were never observed by electron microscopy and V antigen was not
      detected by immunofluorescence at 39 or 41 C in tsB11-infected cells, dense
      amorphous accumulations were formed in the nucleoli and cytoplasm. We suggest
      that the tsB11 function is continuously required for the normal transport of SV40
      virion protein between the cytoplasm, nucleolus, and nucleus and for the assembly
      of capsids and virions. Several possible mechanisms for the altered tsB11
      function or protein are discussed. One of the virion proteins may also be
      involved in some presently undetermined nucleolar function during SV40 productive
      infection.

PMID- 4372411
TI  - Murine type-C virus group-specific antigens: interstrain immunochemical,
      biophysical, and amino acid sequence differences.
AB  - The 30,000-molecular-weight internal protein, p30, was purified from seven
      strains of mouse type-C viruses. The individual p30's showed variation in
      isoelectric points and also intrastrain heterogeneity. The individual p30's could
      be distinguished by peptide map and quantitative complement fixation techniques
      with relatedness estimates of >95%. Amino terminal sequence analysis showed
      variability at position 4 for several p30's with complete homology otherwise
      through 24 residues. The intrastrain heterogeneity in p30 isoelectric points
      could not be explained by common contaminants, as shown by peptide mapping, and
      is more likely based on post-transcriptional modifications. These data provide a
      chemical basis for the recently described type-specific immunological properties
      of individual p30's.

PMID- 4372414
TI  - Plaque formation with simian virus 40: enhancement by dimethyl sulfoxide.
AB  - Dimethyl sulfoxide (DMSO) added to agar overlays during plaque assays of simian
      virus 40 (SV40) in CV1 monkey cells increases the plaque size and number and
      enables plaques to be read several days earlier than usual. DMSO appears to act
      during development of plaques, perhaps by causing cell lysis at smaller burst
      sizes in the presence of near-lethal DMSO concentrations. It does not act
      synergistically in determining virus inactivation with UV light and is equally
      effective on wild type and a late mutant of SV40.

PMID- 4372413
TI  - Replication process of the parvovirus H-1. IV. H-1-specific proteins synthesized
      in synchronized human NB kidney cells.
AB  - The synthesis of two virus-induced proteins, VP1 (mol wt 92,000) and VP2' (mol wt
      72,000), was detected in the cell and in purified virions from H-1 parvovirus
      propagated in synchronous cell cultures.

PMID- 4372415
TI  - Differential effect of phenethyl alcohol on mycoplasmas and enveloped viruses.
AB  - Mycoplasmas are totally inactivated by a 20-min treatment with 1% phenethyl
      alcohol, whereas suspensions of enveloped viruses resist the same treatment. This
      treatment has proved successful in eliminating mycoplasma contamination of a
      virus suspension.

PMID- 4372412
TI  - Type-C RNA virus gene expression in human tissue.
AB  - Partially purified fractions of human tissues have been analyzed by competition
      radioimmunoassay for the presence of two of the principle structural components
      of type-C RNA viruses, the major core protein (p27 to p30) and the major envelope
      glycopeptides (gp69/71). Screening of tissues was carried out by use of a
      heterologous assay system of (125)I-labeled Rauscher murine virus p30 antigen and
      anti-RD 114 virus serum which was found to detect a class of interspecies
      determinants common to murine, feline, and primate viruses. A competitor with the
      same apparent affinity for antibody binding as that of purified viral core
      proteins was found in relatively high concentration in tissues from patients with
      systemic lupus erythematosus, in some neoplastic tissues, and also in normal
      human tissues. This competitor from a lupus spleen chromatographed on
      phosphocellulose and showed size fractionation during gel filtration similar to
      known p27 to p30 viral proteins. An immunologically reactive protein was also
      demonstrated by immunodiffusion and by immunoprecipitation of (125)I-labeled
      human protein with anti-RD 114 p28 serum. Analysis of these human competitor
      proteins with homologous assay systems of viral core proteins and corresponding
      antisera showed that all, including the normal tissue extracts, appear similar to
      core proteins of known viruses, especially the RD 114 and woolly monkey species.
      A hypothesis suggested by these data is that many, if not all, humans harbor at
      least part of the genome of one or more type-C viruses, the properties of which
      are similar to those of viruses from other mammalian species, particularly
      primates.

PMID- 4372416
TI  - In vitro radioisotopic labeling of proteins associated with purified polyoma
      virions.
AB  - An in vitro procedure using [(14)C]formaldehyde and sodium borohydride was used
      to label the proteins of purified polyoma virions. This method, which labeled the
      three capsid proteins and the four internal histones of polyoma virus, did not
      alter the biological and biophysical characteristics of the virus. In addition to
      the seven viral proteins, five additional radioactive peaks were resolved on
      polyacrylamide gels. Four of these peaks could be attributed to growing the virus
      in the presence of serum. The fifth peak appears to be a nonhistone host
      contributed protein made before infection.

PMID- 4372417
TI  - Screening for hyperlipidemia in childhood.

PMID- 4372418
TI  - Islet cell hyperinsulinism in adults and children.

PMID- 4372419
TI  - Pneumocystis carinii pneumonia in an adopted Vietnamese infant. A case of
      diffuse, fulminant disease, with recovery.

PMID- 4372420
TI  - [Mechanism of action of muscle relaxants and its clinical problems].

PMID- 4372422
TI  - [Burkitt's lymphoma; from the standpoint of pathology].

PMID- 4372421
TI  - [Suspected case of chronic lymphocytic leukemia with Auer body-like inclusions
      and abnormal lymphoblasts].

PMID- 4372423
TI  - [Cancer, specially hepatoma, and alkaline phosphatase].

PMID- 4372425
TI  - [Morphological changes of adrenal cortex induced with administration of
      corticosteroid (author's transl)].

PMID- 4372424
TI  - [Effect of diet and exercise on endocrine function (author's transl)].

PMID- 4372426
TI  - Phosphoesterases of hemolytic streptococci.

PMID- 4372427
TI  - Epidemiology of myxo- paramyxovirus infections among cynomolgus monkeys imported
      for laboratory use.

PMID- 4372428
TI  - Selective adsorption of serum proteins to aerosil.

PMID- 4372429
TI  - The effects of amino acids and metals on the infectivity of poliovirus
      ribonucleic acid.

PMID- 4372430
TI  - Growth characteristics of Bordetella pertussis in the chick tracheal organ
      culture.

PMID- 4372431
TI  - Production of mouse interferon with high titers in a large-scale suspension
      culture system.

PMID- 4372432
TI  - Effect of a lactobacillus product administration on the anaerobic intestinal
      flora of aged adults.

PMID- 4372433
TI  - Enhanced production of interferon by temperature shift-down from 37 C to 25 C in
      rabbit cell cultures stimulated with Newcastle disease virus.

PMID- 4372434
TI  - Enhancing effect of interferon pretreatment on interferon production.

PMID- 4372435
TI  - Sensitivity of various H particles of poliovirus to alkaline treatment.

PMID- 4372436
TI  - Typing of herpes simplex virus strains of genital and nongenital origins.

PMID- 4372437
TI  - A sensitive plaque assay for Sendai virus in an established line of monkey kidney
      cells.

PMID- 4372438
TI  - Biochemical basis for narcotic tolerance and physical dependence.

PMID- 4372439
TI  - [Clinical study on tuberactinomycin-N (TUM-N) and viomycin (VM) in retreatment of
      pulmonary tuberculosis (author's transl)].

PMID- 4372440
TI  - [Correlation between indices of hemocoagulation and lipid metabolism in patients
      with myocardial infarct].

PMID- 4372441
TI  - [Typing of hyperlipoproteinemia in patients with coronary atherosclerosis].

PMID- 4372442
TI  - [Histochemical data on the activity of respiratory and glycolytic enzymes in the
      myocardium distant from the zone of an experimental infarct].

PMID- 4372443
TI  - [Chemical composition, metabolism and aggregation of thrombocytes].

PMID- 4372444
TI  - [Role of the thrombocytes in the pathogenesis of atherosclerosis].

PMID- 4372445
TI  - [Phosphorus compounds and their metabolites in ischemic heart diseases].

PMID- 4372446
TI  - [Certain mechanisms of hemodynamic disorders in acute myocardial infarct
      (experimental study)].

PMID- 4372447
TI  - Low-renin hypertension.

PMID- 4372448
TI  - Tubular reabsorption of phosphate after release of complete ureteral obstruction
      in the rat.

PMID- 4372449
TI  - The role of angiotensin in the cardiovascular and renal response to salt
      restriction.

PMID- 4372450
TI  - Evidence for renal glomerular receptors for angiotensin II.

PMID- 4372451
TI  - Phylogeny of the renal effects of angiotensin.

PMID- 4372452
TI  - The adrenal cortex and the kidney.

PMID- 4372453
TI  - A proposed cybernetic system for sodium and potassium homeostasis: coordination
      of aldosterone and intrarenal physical factors.

PMID- 4372454
TI  - Effects of adrenergic nervous system and catecholamines on systemic and renal
      hemodynamics, sodium and water excretion and renin secretion.

PMID- 4372455
TI  - Vasopressin.

PMID- 4372456
TI  - Parathyroid hormone and calcitonin regulation of renal function.

PMID- 4372457
TI  - Estrogens and the kidney.

PMID- 4372459
TI  - [Treatment of burns in children using Lorthioir's debridement method].

PMID- 4372458
TI  - [Glycogen content and glucose-6-phosphatase activity in rabbit tissues following
      prolonged exposure to a hyperbaric helium-oxygen atmosphere].

PMID- 4372460
TI  - [General nursing problems in burn patients].

PMID- 4372461
TI  - [A 6-week traineeship on obstetric ward; a comprehensive nursing report].

PMID- 4372462
TI  - [Hospitalization diagnosis: car accident].

PMID- 4372463
TI  - [Child and surgery].

PMID- 4372464
TI  - [Child and death].

PMID- 4372465
TI  - [School education in the hospital].

PMID- 4372467
TI  - [Discussion on the expert advisors' draft for a new nursing legislation].

PMID- 4372466
TI  - [Joy in playing promotes intelligence].

PMID- 4372468
TI  - [Why is the calorie "dying"? Information on the new weights and measures Bill].

PMID- 4372469
TI  - [Death is not taboo; support in the face of death].

PMID- 4372470
TI  - [From associations with dying patients; professional experiences of a nurse].

PMID- 4372471
TI  - [The nurse's role in relation to the parents of fatally ill children].

PMID- 4372472
TI  - [Does the right to die belong with the right to live? Thoughts on active and
      passive terminal care].

PMID- 4372473
TI  - [Nursing care and treatment of patients with skull-brain injuries].

PMID- 4372474
TI  - [Traffic accident; a nursing care report].

PMID- 4372475
TI  - [Anesthesia and intensive care. VIII. Resuscitation in the hospital].

PMID- 4372477
TI  - [Living with stress].

PMID- 4372476
TI  - [Metacommunicative aspects of organized learning processes].

PMID- 4372478
TI  - [Cardiologic rehabilitation - an extensive process].

PMID- 4372479
TI  - [Nursing care report: heart infarct].

PMID- 4372481
TI  - [First aid in heart infarct; emergency plan for relatives].

PMID- 4372480
TI  - [Diagnosis: anterior wall heart infarct. Extract from a nursing care report].

PMID- 4372483
TI  - [Following a heart infarct: training].

PMID- 4372482
TI  - [Report on a heart catheterization].

PMID- 4372485
TI  - [Anesthesia and intensive care. IX. Teaching aids and teaching methods in
      resuscitation].

PMID- 4372484
TI  - [Cardiovascular diseases in key-words].

PMID- 4372486
TI  - [Equipment and organization of central sterilization in an acute hospital].

PMID- 4372487
TI  - [The effect of predisposition and environment on personality development with
      special reference to language].

PMID- 4372488
TI  - [Planning and organization of nursing services on wards and functional areas].

PMID- 4372489
TI  - Estradiol receptor functions of soluble proteins from target-specific lysosomes.

PMID- 4372490
TI  - The origin of 5alpha-androstane-3alpha, 17beta-diol and its 3beta epimer in
      peripheral blood of immature female rats.

PMID- 4372491
TI  - The intramitochondrial distribution of the 3beta-hydroxysteroid dehydrogenase
      oxosteroid isomerase. A probable redistribution artifact.

PMID- 4372492
TI  - The epidemiologic pathology of carcinomas of the large bowel.

PMID- 4372493
TI  - Gas gangrene-on the basis of 19 observations. Advantages of combining surgery
      with hyperbaric oxygen therapy.

PMID- 4372494
TI  - In vitro studies on the thyroid.

PMID- 4372495
TI  - Intra-axonal transport and degeneration of adrenergic nerve terminals after
      axotomy with long and short nerve stump.

PMID- 4372496
TI  - Is adenylate cyclase the dopamine receptor?

PMID- 4372497
TI  - The autonomic innervation of the exocrine pancreas.

PMID- 4372498
TI  - The APUD cells of the alimentary tract in health and disease.

PMID- 4372499
TI  - Normal mechanisms of fat absorption and derangements induced by various
      gastrointestinal diseases.

PMID- 4372500
TI  - [Burkitt's tumor: etiology, clinic and therapy (author's transl)].

PMID- 4372501
TI  - [Paraganglioma of the larynx (author's transl)].

PMID- 4372502
TI  - [Ovulation physiology. 3. Hormonal feed-backs].

PMID- 4372503
TI  - [Value of plasmatic testosterone determination in female hypertrichosis].

PMID- 4372504
TI  - [Testosterone physiology. (II)].

PMID- 4372505
TI  - Altered stearoyl-CoA desaturase activities in Morris hepatomas 5123C and 7800.

PMID- 4372506
TI  - Tumor lipids: long chain dienoic acid in sphingomyelin.

PMID- 4372507
TI  - Alleged role of boric acid in detritylation of diglyceride-alpha-trityl ethers by
      silicic acid.

PMID- 4372508
TI  - [Effect of a new lipid-reducing preparation (Etofibrat) on hyperlipoproteinemia
      type II. 2].

PMID- 4372509
TI  - The intravenous L-alanine tolerance test as a means for investigating
      gluconeogenesis.

PMID- 4372512
TI  - Editorial: Oestrogen receptors and breast carcinoma.

PMID- 4372510
TI  - A mechanism for hyporeninemic hypoaldosteronism in chronic renal disease.

PMID- 4372511
TI  - Preliminary study of the treatment of nephrolithiasis (calcium stones) with
      diphosphonate.

PMID- 4372514
TI  - Investigation of the lysozyme macromolecule by a spin-labeling method.

PMID- 4372513
TI  - Two types of spin-labels and their interaction with phospholipid micelles and
      mitochondrial enzymes.

PMID- 4372515
TI  - Reaction of DNA with Girard's reagent P: kinetics of the reaction and resistance
      of the product to some nucleases.

PMID- 4372516
TI  - A study of nucleus-cytoplasm interrelationships in a cell-free system with
      isolated rat liver cell nuclei.

PMID- 4372517
TI  - An investigation of the interaction of steroids with human serum albumin by the
      spin-label method.

PMID- 4372518
TI  - Investigation of electron transport in chloroplasts and their fragments by the
      ESR method. Communication I. Electron transport and kinetic characteristics of
      the light-induced ESR signal.

PMID- 4372519
TI  - An investigation of rRNA and synthetic polyribonucleotides by the spin-label
      method.

PMID- 4372520
TI  - Hemoglobin. Cooperativity and electronic properties.

PMID- 4372521
TI  - Distribution of transcribable DNA sequences in mouse liver hepatoma chromatin.

PMID- 4372522
TI  - Covalent coupling of alkaline Bacillus subtilis protease to controlled-pore
      silica with a new simplified coupling technique.

PMID- 4372523
TI  - On the dual role of respiration.

PMID- 4372524
TI  - Requirements for the initiation of polyphenylalanine synthesis by recombined
      ribosomal subunits from yeast.

PMID- 4372525
TI  - The induction of thymidine- and IUdR-resistant variants in P388 mouse lymphoma
      cells by x-rays, UV and mono- and bi-functional alkylating agents.

PMID- 4372526
TI  - [Mutagenic effect of nalidixic acid on bacteriophage T4 (author's transl)].

PMID- 4372527
TI  - The use of different test systems with yeasts for the evaluation of chemically
      induced gene conversions and gene mutations.

PMID- 4372528
TI  - Comparison of the genetic activity of dimethylnitrosamine, ethyl
      methanesulfonate, 2-acetylaminofluorene and ICR-170 in Saccharomyces cerevisiae
      strains D3, D4 and D5 using in vitro assays with and without metabolic
      activation.

PMID- 4372529
TI  - Detection of chemical mutagens using a host-mediated assay (L5178Y) mutagenesis
      system.

PMID- 4372530
TI  - The induction of micronuclei by frameshift mutagens at the time of nucleus
      expulsion in mouse erythroblasts.

PMID- 4372531
TI  - The ultrastructure of the spherules of Emmonsia crescens studied by the technique
      of freeze-etching.

PMID- 4372532
TI  - Editorial: Killer T cells.

PMID- 4372533
TI  - Letter: Collagenases: human and bacterial.

PMID- 4372534
TI  - Poly(C) in animal viral RNAs.

PMID- 4372535
TI  - Detection of cell-dependent cytotoxic antibody to cells infected with herpes
      simplex virus.

PMID- 4372536
TI  - Cyclic GMP stimulates lymphocyte nucleic acid synthesis.

PMID- 4372537
TI  - Membrane antigens of murine leukaemia cells.

PMID- 4372538
TI  - Autologous human B and T lymphoblastoid cell lines.

PMID- 4372539
TI  - Collagenase activity in experimental hepatic fibrosis.

PMID- 4372541
TI  - Caffeine inhibits induction of endogenous C-type virus.

PMID- 4372540
TI  - Activity of CNS depressants related to hydrophobicity.

PMID- 4372542
TI  - Rapid in vivo assay for murine lymphatic leukaemia viruses.

PMID- 4372543
TI  - Antigenic inhibition of cell-mediated cytotoxicity against tumour cells.

PMID- 4372544
TI  - Human times mouse hybrid cells segregating mouse chromosomes and isozymes.

PMID- 4372545
TI  - Transcription, translation and maturation of succinate dehydrogenase during cell
      cycle.

PMID- 4372546
TI  - Evolution of C-type viral genes: inheritance of exogenously acquired viral genes.

PMID- 4372547
TI  - Binding of interferon to gangliosides.

PMID- 4372548
TI  - Octopamine receptors on Aplysia neurones mediate hyperpolarisation by increasing
      membrane conductance.

PMID- 4372549
TI  - Association of polyanion resistance with tumorigenicity and other properties in
      BHK-21 cells.

PMID- 4372550
TI  - Ultrastructural localization of herpes simplex virus antigens on rabbit corneal
      cells using sheep antihuman IgG antihorse ferritin hybrid antibodies.

PMID- 4372552
TI  - Serum concentrations of parathyroid hormone in infants, children, and
      adolescents.

PMID- 4372551
TI  - Effects on the neonate of prednisone and azathioprine administered to the mother
      during pregnancy.

PMID- 4372554
TI  - Extending the scope of the VATER association: definition of the VATER syndrome.

PMID- 4372553
TI  - Peripheral neuropathy and lead poisoning in a child with sickle-cell anemia. Case
      report and review of the literature.

PMID- 4372555
TI  - Occipito-facial-cervico-thoracic-abdomino-digital dysplasia; Jarcho-Levin
      syndrome of vertebral anomalies. Report of six cases and review of the
      literature.

PMID- 4372556
TI  - Possible model reactions for the nitrate reductases.

PMID- 4372557
TI  - Oral contraceptive for men.

PMID- 4372558
TI  - Voltage clamp studies of glutamate synapse.

PMID- 4372559
TI  - Cell-mediated immunity to Epstein-Barr virus and a blocking factor in patients
      with infectious mononucleosis.

PMID- 4372560
TI  - A rapid and simple procedure for the determination of guanosine 3',5'
      monophosphate by use of the protein-binding method.

PMID- 4372561
TI  - [Multiple sclerosis].

PMID- 4372562
TI  - [Tall and short children; supposed and renal growth disorders (with standard
      weight for height in Dutch children). II].

PMID- 4372563
TI  - Cancer genetics: urological system. II.

PMID- 4372564
TI  - [The functional organization of the afferent inputs of cat somatic cortex
      neurons].

PMID- 4372565
TI  - [Reactions of neurons in the secondary auditory zone to acoustic stimulation].

PMID- 4372566
TI  - [Alterations in the cerebral threshold for seizure activity during wakefulness
      and different sleep stages in animals].

PMID- 4372567
TI  - [Inhibitory processes in the neurons of the lizard olfactory bulb].

PMID- 4372569
TI  - [Synaptic effects evoked in lamprey motor neurons by supraspinal and intraspinal
      stimulation].

PMID- 4372568
TI  - [The heterogeneity of connections in the cat midbrain tegmentum].

PMID- 4372570
TI  - [The effect of tendon reflexes on the rhythmic activity of human motor units].

PMID- 4372571
TI  - Dynamics of alpha-fetoprotein production compared to alpha 2-macroglobulin during
      induction of primary hepatoma with 4-dimethylaminoazobenzene in rats.

PMID- 4372572
TI  - Appearance of alpha-fetoprotein in rat serum during induction of primary hepatoma
      with regard to development of histological changes in liver tissue.

PMID- 4372574
TI  - Difference in density of nuclear pores in normal and malignant fibroblasts of
      Syrian hamster.

PMID- 4372573
TI  - Protein synthesizing activities of ribosome-like structure isolated from avian
      myeloblastosis virus in chicken cell-free protein synthesis.

PMID- 4372576
TI  - [Boron-10-slow neutron capture therapy for brain tumors (author's transl)].

PMID- 4372575
TI  - [Cerebral copper-protein complexes in hepatolenticular degeneration studied by
      means of electron spin resonance].

PMID- 4372577
TI  - [Relationship between acromegaly and histological picture in pituitary
      eosinophilic adenoma (author's transl)].

PMID- 4372578
TI  - For goodness sake - let your patients sleep.

PMID- 4372579
TI  - [Enzymes of the eye tissue lysosomes].

PMID- 4372580
TI  - [Spectrum of electronic paramagnetic resonance of bones under the effect of
      ultrasonics (preliminary report)].

PMID- 4372581
TI  - Chronic respiratory problems in neuromyopathic disorders: their nature and
      management.

PMID- 4372583
TI  - I-cell disease (mucolipidosis II): a lysosomopathy.

PMID- 4372582
TI  - Asthma: current concepts.

PMID- 4372584
TI  - [Rhinovirus infection in diseases of the respiratory organs in children].

PMID- 4372585
TI  - [New aspects of the metabolism of vitamin D and the syndrome of hypocalcemic
      rickets].

PMID- 4372587
TI  - Roadside resuscitation.

PMID- 4372586
TI  - [Graves-Basedow type ophthalmopathy and primary hypothyroidism].

PMID- 4372588
TI  - [Hepatitis B virus and its role in human pathology].

PMID- 4372589
TI  - [Suppression of cortisol secretion rates by dexamethasone and response to
      exogenous ACTH in sheep with chronic cannulated adrenal vein].

PMID- 4372590
TI  - Familial and acquired hyperlipoproteinemias in children and adolescents.

PMID- 4372591
TI  - Soft-tissue swellings.

PMID- 4372592
TI  - Relipidation of phospholipid-depleted microsomal particles with high glucose 6
      phosphatase activity.
AB  - Microsomal particles enriched up to 20-fold in glucose 6-phosphatase activity (as
      compared to crude microsomal fractions) were prepared from livers of
      phenobarbital-treated, normal, and diabetic rats by a method involving sucrose
      density gradient centrifugation through a layer containing deoxycholate, followed
      by flotation of the delipidated particles in a phospholipid-detergent mixture.
      The flotation with phospholipid resulted in the extraction of additional protein,
      in a corresponding increase in specific activity, and in relipidation of the
      particles to their original phospholipid content. Detergents alone did not
      extract any additional protein. Relipidation caused a change in the properties of
      the microsomal membrane, as indicated by a 4-fold decrease in the K(m) for
      glucose 6-phosphate and mannose 6-phosphate. The maximal rate was not affected.
      The crude homogenate of diabetic rat liver contained more latent enzyme than that
      of normal rats. The diabetic rats also yielded purified microsomal particles of
      specific glucose 6-phosphatase activity twice that of normal and five times that
      of phenobarbital-treated rats, indicating that some regulatory mechanism exists
      for the incorporation of different amounts of the enzyme into the endoplasmic
      reticulum.

PMID- 4372593
TI  - Degradation of pseudoviral DNA after infection of mouse cells with polyoma
      pseudovirions.
AB  - When mouse cells are infected with [(3)H]-thymidine-labeled polyoma
      pseudovirions, as much as 11% of the input pseudoviral radioactivity is found in
      the recipient cell DNA. However, the radioactivity found in the recipient cell
      DNA virtually disappears when nonradioactive thymidine and deoxycytidine, or D
      arabinosyl cytosine, are added to the medium. The radioactivity found in the
      recipient cell DNA appears to be the result of the breakdown of pseudoviral DNA
      to precursors of DNA and the utilization of these precursors for the synthesis of
      cell DNA.

PMID- 4372594
TI  - Aldosterone-induced increase in protein phosphatase activity of toad bladder.
AB  - A study has been carried out of the effect of aldosterone on the endogenous
      phosphorylation and dephosphorylation of membrane-bound and of soluble proteins
      from toad bladder. Membrane-bound protein D (apparent molecular weight, 49,000),
      a protein which may possibly be involved in the regulation of sodium transport
      across the mucosal epithelium of toad bladder, contained a substantial fraction
      of the radioactive phosphate incorporated into membrane proteins; moreover, it
      was the only protein to appear consistently in autoradiographs of polyacrylamide
      gels of phosphorylated membrane proteins. Pretreatment of toad bladder slices
      with aldosterone caused an increase in the endogenous dephosphorylation of
      membrane-bound protein D. A half-maximal increase in this dephosphorylation
      occurred at an aldosterone concentration of 20-40 nM. The increase in protein D
      phosphatase activity induced by aldosterone was prevented by inhibitors of RNA
      and protein synthesis as well as by spironolactone, a specific antagonist of
      aldosterone. The mineralocorticoid, 9alpha-fluorohydrocortisone, also increased
      protein D phosphatase activity, but testosterone did not. Aldosterone also
      increased the removal of [(32)P]phosphate from protein D in the cell sap. In
      contrast to the increase in protein D phosphatase activity, aldosterone had
      little effect on the phosphorylation of protein D by endogenous protein D kinase.
      In some experiments, effects of aldosterone and of cAMP, qualitatively similar to
      those found with protein D, were also observed on the phosphorylation and
      dephosphorylation of a protein with an apparent molecular weight of 37,000, in
      both the microsomal and cell sap fractions. No consistent effect of preincubation
      with aldosterone or of cAMP was observed on any membrane-bound or cell sap
      protein other than protein D and the 37,000 dalton protein.

PMID- 4372595
TI  - Synthesis of viral DNA in the cytoplasm of duck embryo fibroblasts and in
      enucleated cells after infection by avian sarcoma virus.
AB  - TWO LINES OF EVIDENCE INDICATE THAT SYNTHESIS OF VIRAL DNA OCCURS IN THE
      CYTOPLASM OF DUCK EMBRYO FIBROBLASTS INFECTED WITH AVIAN SARCOMA VIRUS: (i) viral
      DNA is detected first in the cytoplasmic fraction of infected cells and
      subsequently in the nuclear fraction; and (ii) viral DNA is synthesized at a
      normal rate in cells infected after enucleation with cytochalasin B. The presence
      of viral DNA in the cytoplasmic fraction is not a consequence of leakage of newly
      synthesized viral DNA from the nucleus, since it remains in nuclear fractions
      late after infection when integration of viral DNA into the host genome is
      inhibited by ethidium bromide.

PMID- 4372596
TI  - Enhancement of dopamine-stimulated adenylate cyclase activity in rat caudate
      after lesions in substantia nigra: evidence for denervation supersensitivity.
AB  - Unilateral radiofrequency lesions or chemical lesions with 6-hydroxydopamine were
      produced in the substantia nigra of rat brain in order to destroy dopaminergic
      innervations to caudate nucleus and thereby to produce functional denervation
      supersensitivity. Both types of lesions resulted in enhanced stimulation of
      caudate adenylate cyclase (EC 4.6.1.1) activity by dopamine at all dopamine
      concentrations tested, with more marked enhancement at the lower concentrations.
      Response to another dopamine agonist, 1-(3,4-dihydroxybenzyl)-4-(20pyrimidinyl)
      piperazine (S584) was also enhanced. 6-Hydroxydopamine lesions resulted in
      selective enhancement of the dopamine-stimulated component of adenylate cyclase,
      whereas radiofrequency lesions resulted also in a marked decrease in basal
      activity. It is postulated that the basal activity of caudate represents
      primarily an adenylate cyclase distinct from that stimulated by dopamine and
      destroyed only by the less selective radiofrequency lesion. The enhancement of
      dopamine-sensitive adenylate cyclase after lesions serves as indirect evidence
      for a significant role of this system in the transmitter function of dopamine and
      indicates, furthermore, that it is directly involved in dopamine receptor
      supersensitivity in vivo produced by denervation.

PMID- 4372597
TI  - Receptors from glucocorticoid-sensitive lymphoma cells and two clases of
      insensitive clones: physical and DNA-binding properties.
AB  - Mouse lymphoma tissue culture cells (S49.1A) are normally killed by
      dexamethasone, a synthetic glucocorticoid hormone. Dexamethasone-resistant clones
      have been selected from this line, some of which retain the ability to
      specifically bind dexamethasone. Addition of [(3)H]dexamethasone to cultures,
      followed by cell fractionation, reveals that the nuclear transfer of hormone
      receptor complexes in some of these variant clones is deficient (nt(-)), while
      others show increased nuclear transfer (nt(i)) relative to the parental line. Two
      independently selected members of each class have been studied here, in an effort
      to elucidate the molecular determinants involved in the receptor-nucleus
      interaction in vivo. The labeled receptors in cell-free extracts bind to DNA
      cellulose, but only after previous incubation of the extract at 20 degrees ,
      similar to the treatment required for cell-free interaction of receptors with
      nuclei. More importantly, the apparent DNA-binding affinity of the nt(-)
      receptors is lower than the wild type, whereas the nt(i) receptors bind DNA with
      an affinity higher than the parental molecules. The parallelism of nuclear and
      DNA binding, together with the observations that the receptors from the variants
      have sedimentation properties different from the wild-type cells, lead us to
      conclude that (i) these variants may contain altered receptor molecules and (ii)
      DNA is probably the primary nuclear binding site for steroid receptors in vivo.

PMID- 4372599
TI  - Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma
      cells.
AB  - The poly(A) tract found in eukaryotic mRNA was used to study methylation in mRNA
      obtained from Novikoff hepatoma cells. Methyl labeling of RNA was achieved with L
      [methyl-(3)H]methionine under conditions that suppress radioactive incorporation
      into the purine ring. RNA that contains a poly(A) segment was obtained from
      polysomal RNA by chromatography on oligo(dT)-cellulose. Sucrose density gradient
      centrifugation of this RNA revealed a pattern expected for mRNA. The composition
      of the methyl-labeled nucleosides in the RNA was analyzed after complete
      enzymatic degradation to nucleosides. By use of DEAE-cellulose (borate)
      chromatography, which separates 2'-O-methylnucleosides from normal and base
      methylated nucleosides, about 50% of the radioactivity was recovered in the 2'-O
      methylnucleoside fraction and 50% in the base-methylnucleoside fraction. High
      speed liquid chromatography (Aminex A-5) of the 2'-O-methylnucleoside fraction
      produced four peaks coincident with the four 2'-O-methylnucleoside standards.
      Analysis of the base-methylnucleoside fraction revealed a unique pattern. While
      ribosomal RNA and tRNA possessed complex base-methylnucleoside patterns, the
      distribution in mRNA was quite simple, consisting predominantly of N(6)
      methyladenosine. These results demonstrate a unique distribution of methylated
      nucleosides in mRNA. By analogy to ribosomal RNA synthesis, the presence of
      methylnucleosides in mRNA may reflect a cellular mechanism for the selective
      processing of certain mRNA sequences.

PMID- 4372598
TI  - Induction of type-C RNA virus by cycloheximide: increased expression of virus
      specific RNA.
AB  - Mouse cells contain the genetic information for multiple endogenous type-C RNA
      viruses. The mechanisms by which the cell controls expression of these naturally
      integrated viruses are not yet known. Recently, chemicals that inhibit protein
      synthesis have been shown to induce a specific type-C virus at high frequency
      from BALB/c mouse embryo cells. In the present studies, virus activation in
      response to a representative translational inhibitor, cycloheximide, is
      demonstrated to be transient, with virus release primarily occurring within the
      first 12-24 hr following drug exposure. Analysis of virus-specific RNA in cells
      by molecular hybridization revealed an absolute increase in viral RNA
      concentration in cycloheximide-treated cells. This was blocked by simultaneous
      exposure of the cells to actinomycin D. Further, inhibition of RNA synthesis
      during but not subsequent to cycloheximide exposure prevented virus activation.
      These findings show that virus induction by cycloheximide requires de novo RNA
      synthesis during but not after drug exposure and suggest that the required RNA
      species may be that of the virus itself. The present results are consistent with
      the hypothesis that translational inhibitors prevent synthesis of a labile
      protein whose normal action is to inhibit viral RNA transcription or to cause
      degradation of viral RNA.

PMID- 4372600
TI  - The glycine synaptic receptor: evidence that strychnine binding is associated
      with the ionic conductance mechanism.
AB  - The ability of a series of anions to inhibit [(3)H]strychnine binding to spinal
      cord synaptic membranes correlates closely with their neurophysiologic capacity
      to reverse inhibitory postsynaptic potentials in the mammalian spinal cord. Seven
      neurophysiologically active anions are also effective inhibitors of
      [(3)H]strychnine binding with mean effective doses ranging from 160 to 620 mM.
      Seven other anions that are ineffective neurophysiologically also fail to alter
      strychnine binding. Chloride inhibits strychnine binding in a noncompetitive
      fashion. Hill plots of the displacement of [(3)H]strychnine by chloride give
      coefficients of 2.3-2.7. The inhibition of strychnine binding by these anions
      suggests that strychnine binding is closely associated with the ionic conductance
      mechanism for chloride in the glycine receptor.

PMID- 4372601
TI  - Differences between laboratory strains of Epstein-Barr virus based on
      immortalization, abortive infection, and interference.
AB  - Biologic activities of extracellular Epstein-Barr virus (EB virus) from two
      laboratory strains, namely, P(3)J-HR-1 (P-H) from Burkitt lymphoma and B95-8
      (B95) from infectious mononucleosis, were compared. Virus stocks from both
      sources contained approximately the same number of virions. Virus from the P-H
      line induced "early antigen" in six nonproducer EB virus genome carrier cell
      lines; virus from B95 did not induce "early antigen." Extracellular virus from
      B95 regularly caused lymphocytes from human umbilical cords to form continuous
      lines (immortalization); P-H virus did not cause primary cultures of human
      lymphocytes to grow continuously. B95 virus stimulated DNA synthesis as
      determined by rate of incorporation of [(3)H]thymidine into acid-insoluble
      material; P-H virus did not stimulate DNA synthesis. Pretreatment of lymphocytes
      with undiluted P-H virus inhibited immortalization and stimulation of DNA
      synthesis by B95 virus. The inhibitory properties of the P-H virus were
      sedimented at 100,000 x g and inactivated by heat and UV irradiation;
      interference by the P-H virus was neutralized by human serum with antibody to EB
      virus and not by antibody-negative human serum. The hypothesis most consistent
      with these results is that the P-H virus is defective in gene(s) needed for
      initiation of immortalization. We speculate that the absence of this gene allows
      early antigen to be expressed upon super-infection of nonproducer cell lines. The
      availability of two laboratory strains of EB virus which differ in biologic
      behavior provides starting material for analysis of the mechanism of lymphocyte
      immortalization by EB virus and of virus structural differences which affect
      immortalization.

PMID- 4372602
TI  - Carbohydrate composition of the membrane glycoprotein of vesicular stomatitis
      virus grown in four mammalian cell lines.
AB  - The carbohydrate composition of the membrane glycoprotein of vesicular stomatitis
      virus has been determined for virus grown in four different mammalian cell lines.
      The glycoprotein contains mannose, galactose, N-acetylglucosamine, and neuraminic
      acid as the major carbohydrate components, whereas N-acetyl-galactosamine and
      fucose are present in lesser amounts. The glycoprotein contains approximately 9
      10% carbohydrate regardless of the host cell in which it is synthesized. Small
      quantitative differences are evident in the composition of the component sugars
      of the glycoprotein when the virus is grown in different host cells, and the
      glycoprotein of virus grown in a mouse fibroblast line (L cells) lacks fucose.
      The major oligosaccharide moieties of the virus glycoprotein from all cells are
      approximately the same size (3000-3400 daltons). The data presented here, in
      conjunction with previous data, indicate that the viral glycoprotein contains two
      major oligosaccharide constituents regardless of the host cell in which it is
      synthesized.

PMID- 4372603
TI  - Guanosine 3':5'-monophosphate-dependent protein kinases in mammalian tissues.
AB  - The mammalian protein kinase activity stimulated preferentially by low
      concentrations of guanosine 3':5'-monophosphate (cyclic GMP), but not by
      adenosine 3':5'-monophosphate (cyclic AMP), was readily assayed in a modified
      incubation system that contained a neutral phosphate buffer, protein kinase
      modulator, and arginine-rich histone. Cyclic GMP-dependent protein kinase
      activity assayed under these conditions was about two to three orders of
      magnitude higher than that previously detected. The enzyme activity occurred in
      all guinea pig and rat tissues (lung, heart, aorta, brain, liver, ileum, adipose,
      and pancreatic islets) examined. The activity can be separated from the cyclic
      AMP-dependent protein kinase activity, also present in the same tissues, by means
      of either Sephadex G-200 gel filtration or ammonium sulfate fractionation. The
      cyclic GMP-dependent enzyme preparations had K(a) values for cyclic GMP ranging
      from 0.03 to 0.12 muM, compared to the K(a) values for cyclic AMP ranging from
      0.6 to 3.8 muM. The presence of phosphate and protein kinase modulator was
      essential for maximal cyclic GMP-dependent enzyme activity. The occurrence of
      high levels of cyclic GMP-dependent protein kinase activity in mammalian tissues
      clearly suggests that it may serve as a "target" enzyme for cyclic GMP, mediating
      many biological effects of this cyclic nucleotide.

PMID- 4372604
TI  - Stimulation of synthesis of free chondroitin sulfate chains by beta-D-xylosides
      in cultured cells.
AB  - Previous studies have shown that D-xylose partially overcomes the puromycin
      inhibition of chondroitin sulfate synthesis in cultured chick embryo
      chondrocytes. Likewise, D-xylose stimulates chondroitin sulfate synthesis by limb
      bud mesenchyme cells previously treated with BrdU or limb bud cartilage cells
      treated with puromycin. The studies reported here show that p-nitrophenyl-beta-D
      xylopyranoside and 4-methyl-umbelliferyl-beta-D-xylopyranoside cause a much
      greater stimulation than does D-xylose and are active at much lower
      concentrations. In contrast to D-xylose, the xylosides strikingly stimulate
      chondroitin sulfate synthesis in predifferentiated mesenchyme cells. The
      xylosides stimulate synthesis of chondroitin sulfate by rat glial cell tumor
      cells (RC-6), a mouse neuroblastoma (C1300, NB41A), and two strains of cultured
      rat hepatoma cells (HTC, H(4)). These results indicate that certain types of
      nonconnective tissue cells contain the enzymic machinery for synthesis of
      chondroitin sulfate which is normally not utilized because of limited synthesis
      of core protein and/or xylosyltransferase. The beta-xylosides may be used as a
      probe of the capacity of various cell types to synthesize sulfated
      glycosaminoglycans.

PMID- 4372605
TI  - Initiation of oncogenic transformation of mouse lymphocytes in vitro by Abelson
      leukemia virus.
AB  - While C-type RNA viruses are known to induce leukemias and lymphomas, oncogenic
      transformation of lymphoid cells by them in vitro has not been reported. In this
      study, splenocytes from female BALB/c mice were infected in vitro with Abelson
      virus, a C-type RNA virus that induces nonthymic lymphomas and plasmacytomas in
      mice. The cells were transplanted into recipients of different karyotype, either
      male BALB/c mice or hybrid BALB/c x AL/N (CALF1) mice, which bear the Rb(5.19)1Wh
      translocation. Transplants of eight of the resulting tumors (one plasmacytoma and
      seven lymphomas) contained cells of donor BALB/c karyotype, indicating that
      transformation of splenocytes occurred in vitro.

PMID- 4372606
TI  - Correlation between thermal death and membrane fluidity in Bacillus
      stearothermophilus.
AB  - Paramagnetic resonance spectra of spin labels partitioned into spheroplast
      membranes of Bacillus stearothermophilus indicate lateral lipid phase
      separations. Cells adjust their lipid composition in response to temperature
      changes so that the same change of state in membrane phospholipids is achieved at
      the respective growth temperature. A temperature-sensitive mutant that fails to
      change its lipid composition above a certain temperature can survive only up to
      the higher temperature boundary for lateral phase separation. These data are
      interpreted to indicate that the maximal and minimal growth temperatures of
      thermophiles are regulated by the onset and conclusion of phase separations of
      the particular lipid composition they synthesize. It is suggested that isolated
      lipid domains are required for functional membrane assembly.

PMID- 4372607
TI  - Chromosome assignment of the T-antigen gene of simian virus 40 in African green
      monkey cells transformed by adeno 7-SV40 hybrid.
AB  - Somatic cell hybrids between mouse cells deficient in thymidine kinase
      [ATP:thymidine 5'-phosphotransferase (EC 2.7.1.75)] and two different monkey cell
      lines transformed by an adeno 7-SV40 hybrid have been produced using both a
      semiselective and a double selective procedure. Concordant segregation of the
      expression of SV40 T antigen with a specific monkey chromosome has been observed
      in all the mouse-monkey hybrid clones examined. Subcloning of three SV40 T
      antigen positive hybrid clones resulted in their segregation into SV40 T antigen
      positive and negative subclones. Positive correlation between the SV40 T antigen
      and the same monkey chromosome has been observed in all the subclones examined.

PMID- 4372608
TI  - Alterations in glucose metabolism in chick-embryo cells transformed by Rous
      sarcoma virus: intracellular levels of glycolytic intermediates.
AB  - Chick-embryo cells, transformed with Rous sarcoma virus, show enhanced rates of
      sugar transport and glycolysis. Determination of intracellular concentrations of
      glycolytic intermediates suggests that the enhanced glycolytic flux is due to
      increased activities of hexokinase (ATP:D-hexose 6-phosphotransferase, EC
      2.7.1.1), phosphofructokinase, (ATP:D-fructose-1-phosphate 6-phosphotransferase,
      EC 2.7.1.56), and pyruvate kinase (ATP:pyruvate 2-O-phosphotransferase, EC
      2.7.1.40), and not directly to the increased glucose transport. This conclusion
      is supported by the finding that the intracellular concentration of free glucose
      is decreased, rather than increased, in the transformed cells. The present
      observations suggest that the increased glycolytic flux is related to an
      increased rate of phosphorylation of glucose, and that hexokinase in the
      transformed cells is at least partly released from its normal control mechanism
      involving feedback inhibition by glucose-6-P.

PMID- 4372609
TI  - Myosin is a component of the cell surface of cultured cells.
AB  - Antisera to myosin from mouse L929 cells, mouse uterus, and rabbit skeletal
      muscle have been prepared in goats. Each antiserum shows specific reaction by
      immunodiffusion only to the myosin against which it was prepared. Antiserum
      against L cell myosin agglutinates L929 cells and shows surface localization in
      unfixed cells by indirect immunofluorescence. This reaction is prevented by
      immunoabsorption with L cell myosin, but not by absorption with mouse uterine or
      rabbit skeletal muscle myosins. Elution of the antibody from L cell myosin
      antiserum that absorbs to fixed L cells yields antibody reactive to L cell myosin
      in immunodiffusion. At the ultrastructural level, surface localization is also
      evident with a peroxidase bridge immunocytologic method as a uniform distribution
      of surface label. Antiserum against L cell myosin also shows localization on the
      surface of other cells of rodent origin (3T3-4, NRK, MNRK, KNRK, and MEF) and
      HeLa cells, but not with some other cells of human origin (ALL and WI-38). The
      reactivity with antibody of the plasma membrane myosin is unaffected by trypsin
      treatment or fixation with 0.5-2.0% formalin. These results strongly suggest that
      myosin in cultured nonmuscle cells is a component of the plasma membrane, a
      finding of possible significance in studying the mechanisms regulating the
      motility, morphology, and growth of these cells.

PMID- 4372610
TI  - Evidence for the involvement of sulfhydryl oxidation in the regulation of fat
      cell hexose transport by insulin.
AB  - Previous studies have shown that the oxidants Cu(++), H(2)O(2), and diamide mimic
      the stimulatory effect of insulin on 3-O-methylglucose transport in isolated fat
      cells. The present experiments were designed to determine whether sulfhydryl
      oxidation plays a key role in the activation of the glucose transport system. It
      was found that reductants such as dithiothreitol inhibited 3-O-methylglucose
      transport rates and that this effect was reversible when cells were washed free
      of reducing agent. Treatment of cells with 1 mM N-ethylmalcimide for 5 min
      completely blocked the actions of insulin and oxidants on hexose transport
      without affecting control transport system activity. Under these conditions,
      binding of (125)I-labeled insulin to fat cell surface receptors was inhibited by
      only about 50%. Addition of insulin or oxidants to fat cells for 10 min before
      addition of N-ethylmaleimide completely prevented the inhibitory effect of N
      ethylmaleimide on the activated transport system. This protective effect on
      transport rates appears to reside at a site that is altered by insulin subsequent
      to hormone-receptor interaction, since prior treatment of fat cells with insulin
      did not prevent the partial inhibitory effect of N-ethylmaleimide on insulin
      receptors. Furthermore, treatment of cells with N-ethylmaleimide after incubation
      with insulin prevented the elevated transport rates from returning to control
      levels when either the cells were washed free of hormone or insulin binding to
      its receptors was disrupted by trypsin digestion. However, transport rates in
      these cells treated with N-ethylmaleimide remained sensitive to cytochalasin B,
      phlorizin, and reductants. These data suggest that a component of the glucose
      transport system in isolated fat cells must be maintained in its disulfide state
      for expression of transport activity. Further, the results are consistent with
      the concept that the binding of insulin to cell surface receptors triggers
      sulfhydryl oxidation in this component, which prevents its reaction with N
      ethylmaleimide.

PMID- 4372611
TI  - Viral DNA in transformed cells. III. The amounts of different regions of the SV40
      genome present in a line of transformed mouse cells.
AB  - (32)P-Labeled SV40 DNA was treated sequentially with restricting endonucleases
      EcoRI and Hpa I, and the resulting four fragments of DNA were separated by gel
      electrophoresis. The kinetics of renaturation of each of the fragments and of
      complete SV40 DNA were measured in the presence of DNA extracted from the SVT2
      line of SV40-transformed mouse cells. It was found that these cells contain about
      six copies of a segment of DNA which includes the early region of the SV40
      genome, and about one copy of the late viral sequences. To map the region of the
      viral genome which is transcribed in SVT2 cells, separated strands of each of the
      four fragments were prepared and hybridized to total transformed cell RNA. Part
      of the E strands of the two DNA fragments (A and C) which span the early region
      of the SV40 genome were found to enter the hybrid.

PMID- 4372612
TI  - Vitamin D: concerning the relationship between molecular topology and biological
      function.
AB  - Structure-function relationships for vitamin D, its metabolites, and analogs are
      discussed with particular emphasis on the A-ring conformation. It is emphasized
      that the A-ring of these seco-steroids consists of a pair of rapidly
      equilibrating chair conformers. As a consequence, different chair conformations
      produce different orientations of substituent groups in the A-ring. It is
      proposed that the 1alpha-hydroxyl of 1alpha,25-dihydroxyvitamin D(3) or its
      geometric equivalent in analogs must occupy the equatorial, as opposed to the
      axial, orientation for optimization of biological activity. This proposal is
      discussed in relation to existing published data on structure-function
      relationships and the steroid hormone model of action for the biologically active
      form of vitamin D. This three-dimensional topological model suggests the
      synthesis of other vitamin D analogs.

PMID- 4372613
TI  - Further comparison of predicted and experimentally determined structure of
      adenylate kinase.
AB  - An analysis is made of various predictive methods used to locate alpha-helices
      and beta-sheets in proteins. The analysis is based on attempts to locate the
      alpha-helices and beta-sheets in adenylate kinase (ATP:AMP phosphotransferase EC
      2.7.4.3) from the sequence without prior knowledge of the x-ray findings.
      Specification of the beta-sheet breaking and alpha-helix breaking tripeptides, a
      method independent of the others combined with the best of the other methods
      would substantially reduce the prediction of nonexistent beta-sheets and to a
      lesser extent would aid in locating alpha-helices.

PMID- 4372614
TI  - Reciprocal inhibition of mouse leukemia virus infection by Fv-1 allele cell
      extracts.
AB  - Soluble extracts of mouse cells with Fv-1(n) or Fv-1(b) gene alleles specifically
      and reciprocally inhibit infection of B- or N-tropic mouse leukemia viruses in
      permissive cell cultures. NB-tropic virus infection was not inhibited by either
      cell extract. Extracts from Fv-1(-) cells did not inhibit infection by the three
      virus host-range types, but N- or B-tropic virus infection of Fv-1(-) cells was
      inhibited by extracts of the nonpermissive cells, and Fv-1(nb) cell extracts
      inhibited both viruses. The maximum degree of inhibition was 50-80% as determined
      by immunofluorescent or plaque assays, with extracts containing up to 500 mug/ml
      of nonpermissive cell protein. The inhibitor(s) is relatively unstable since
      activity is lost after 2 hr at 37 degrees or 30 min at 56 degrees . The
      inhibitor(s) was most effective if added 2 hr before or within 2 hr after
      infection, did not react with the virus directly, inhibit virus attachment, or
      inhibit the normal cell functions tested. These results indicate that
      nonpermissive mouse cells contain a product, possibly determined by the Fv-1
      gene, which inhibits some early postpenetration event(s) in leukemia virus
      infection.

PMID- 4372615
TI  - Evidence for crossing-over between avian tumor viruses based on analysis of viral
      RNAs.
AB  - The RNAs of several avian tumor virus recombinants that had inherited their focus
      forming ability from a sarcoma virus and their host range marker from a leukosis
      virus were investigated. Electrophoretic analyses showed that the cloned sarcoma
      virus recombinants contained only size class a RNA, although they had acquired a
      marker that resided on class b RNA in the leukosis virus parent. Class a RNA of
      different recombinant clones, derived from the same pair of parental viruses and
      selected for the same biological markers, differed slightly in electrophoretic
      mobility from each other and from the parental sarcoma virus. They were also
      found to have different fingerprints of RNase T1-resistant oligonucleotides. The
      average complexity of the 60-70S RNA prepared from Prague Rous sarcoma virus of
      subgroup B was estimated to be 3.5 x 10(6) daltons from the size of 20 RNase T1
      resistant oligonucleotides, which represented 3.9% of the RNA and that of a
      recombinant to be 3.3 x 10(6) daltons from 23 oligonucleotides, which represented
      4.7% of the RNA. This result suggests that the genome of wild-type and of
      recombinant RNA tumor viruses is polyploid. The sum of these observations led us
      to propose that recombination among avian tumor viruses occurred by crossing-over
      between homologous pieces of nucleic acid.

PMID- 4372616
TI  - Changing the actions of neuroactive drugs by changing brain protein synthesis.
AB  - Diminution of cerebral protein synthesis diminished the cerebral responses of
      mice to some neuroactive drugs, while an increase in synthesis increased the
      responses. Protein synthesis in whole brains (tested in vitro) was diminished by
      giving living mice different inhibitors by different routes. The inhibitors
      tested (chloramphenicol, cycloheximide, and puromycin) diminished the behavioral
      responses of the mice to levodopa without affecting either its cerebral uptake or
      its conversion to dopamine. A diminution of the reactions of dopaminergic
      receptors was suggested by the diminished responses to the dopaminergic drug,
      apomorphine, while participation of cholinergic ones was suggested by experiments
      with oxotremorine. Proof that receptors had been specifically involved was
      secured on homogenized caudate nuclei from chloramphenicol-treated mice, in which
      the dopamine-activated production of cyclic AMP was markedly diminished. A
      stimulator of cerebral protein synthesis, the artificial double-stranded RNA,
      poly(I).poly(C), increased the behavioral responses to these three drugs while it
      increased the dopamine-activated production of cyclic AMP. Since all these
      experimental increases or decreases in the responses to drugs required the lapse
      of only a few hours, proteins with rapid turnover rates must be critical in the
      activation of several kinds of cerebral receptors.

PMID- 4372617
TI  - Biological activity of a growth factor for ovarian cells.
AB  - The biological activity of a protein growth factor is described. This factor was
      isolated from bovine pituitary tissue, and its activity was tested on cells of
      rat ovarian origin. Activity was assayed as growth-promoting potential measured
      by cell counts and is concentrationdependent. Similar growth stimulation was not
      produced by several cyclic nucleotides tested, neither was there crossreactivity
      between this growth factor and a chemically similar one produced by rat liver
      cells.

PMID- 4372618
TI  - The pancreatic beta-cell recognition of insulin secretagogues: does cyclic AMP
      mediate the effect of glucose?
AB  - Insulin release and the content of cAMP were studied in microdissected pancreatic
      islets of noninbred ob/ob (obese) mice. In the absence of 3-isobutyl-1
      methylxanthine, a phosphodiesterase inhibitor, 20 mM glucose had no effect on
      cAMP save a very small initial rise detectable by a freeze-stop perifusion
      technique only. However, combined with this methylxanthine, 20 mM glucose
      produced significant increases of cAMP both in perifused islets and in islets
      conventionally incubated in closed vials. Glucose shared this capacity to raise
      the cAMP level with D-glyceraldehyde and 1,3-dihydroxyacetone.
      Isobutylmethylxanthine (0.05-1.0 mM) or 5 mug/ml of cholera toxin, an activator
      of adenylate cyclase, also increased the islet cAMP level; the effects of the
      methylxanthine, whether or not combined with cholera toxin, were potentiated by
      glucose. Isobutylmethylxanthine (0.05-1.0 mM) or 5 mug/ml of cholera toxin
      potentiated insulin release in response to 20 mM glucose. However, only 0.5-1.0
      mM isobutylmethylxanthine stimulated insulin release in the presence of 3 mM
      glucose, whereas 0.05-0.1 mM isobutylmethylxanthine or 5 mug/ml of cholera toxin
      had no effect on secretion at the low glucose concentration. These discrepancies
      between cAMP-promoting and insulin-releasing activities suggest that glucose does
      not initiate insulin release by activating the beta-cell adenylate cyclase. By
      being metabolized in the beta-cells, glucose may both create a release-initiating
      signal not identical with cAMP and enhance cAMP formation, leading to
      potentiation of the effect of the initiator signal.

PMID- 4372619
TI  - Purification and separation of pyridine nucleotide-linked dehydrogenases by
      affinity chromatography techniques.
AB  - A number of different dehydrogenases have been shown to bind to Sepharose-bound
      N(6)-(6-aminohexyl)-AMP. These dehydrogenases can be specifically eluted by
      binary adducts of NAD(+) or with cofactor gradients. In such manner pure enzymes
      can be obtained from crude extracts, as demonstrated in the purification on a
      preparative scale of lactate dehydrogenase from dogfish muscle. The data
      presented indicate the usefulness of general ligands as affinity agents. The
      techniques are particularly adaptable for the isolation of human mutant enzymes
      in blood or in the purification and concentration of enzymes present at low
      levels in fluids or tissues, as shown in the extensive purification of serum
      lactate dehydrogenase and glucose 6-phosphate dehydrogenase from hemolysate.
      lsoenzymes with different affinities for co-enzymes can be separated by affinity
      techniques. Application of affinity techniques may lead to the separation of
      isoenzymes or mutant enzymes that are not separable by electrophoretic methods.

PMID- 4372620
TI  - The contribution of subunits of thyroid stimulating hormone to the binding and
      biological activity of thyrotropin.
AB  - The binding of bovine TSH (thyroid stimulating hormone), LH (luteinizing
      hormone), and their subunits to the TSH receptor of beef thyroid membranes was
      compared to stimulation by these agents of adenylate cyclase [ATP pyrophosphate
      lyase(cyelizing), EC 4.6.1.1] in the same membranes, glucose oxidation in dog
      thyroid slices, and the secretory process in mouse thyroids in vitro (colloid
      droplet formation) and in vivo (hormone release). The beta-subunits of TSH and LH
      can bind to the TSH receptor and can activate thyroid function in vitro. In
      contrast, the alpha-subunit of TSH binds negligibly to the TSH receptor and has
      very low potency for stimulation of thyroid function (except for colloid droplet
      formation). Neither binding nor the biological activity of the beta-subunits can
      be accounted for by TSH contamination, whereas this cannot be ruled out for alpha
      TSH. LH binds to the TSH receptor even better than the beta-subunit of TSH but
      the increased binding does not result in a corresponding activation of thyroid
      function. Neither alpha- nor beta-TSH alone can induce more than 4-8% of the
      response to intact TSH in any of the investigated parameters. It is proposed that
      the beta-subunit has within its structure the primary determinants which are
      necessary to stimulate biological activity, whereas the alpha-subunit imposes
      conformational changes on the beta-subunit which in intact TSH promote binding
      and biological activity commensurately but in LH promote only binding.

PMID- 4372621
TI  - Reversibility of the pyrophosphoryl transfer from ATP to GTP by Escherichia coli
      stringent factor.
AB  - The stringent factor-catalyzed, ribosome-dependent synthesis of guanosine
      polyphosphates is found to be reversible. The reverse reaction specifically
      requires 5'-AMP as the pyrophosphoryl acceptor, and guanosine 5'-triphosphate-3'
      diphosphate is preferentially utilized as the pyrophosphoryl donor. The primary
      products of the reaction are GTP and ATP. The reverse reaction is strongly
      inhibited by the antibiotics thiostrepton and tetracycline, and by ATP and beta
      gamma-methylene-adenosine-triphosphate, but not by ADP, GTP, and GDP. The reverse
      reaction occurs under conditions for nonribosomal synthesis. The overall reaction
      for stringent factor-catalyzed guanosine polyphosphate formation may thus be
      formulated: (p)pp5'G + ppp5'A right harpoon over left harpoon (p)pp5'G3'pp +
      p5'A.

PMID- 4372622
TI  - Distribution and fate of synthetic lipid vesicles in the mouse: a combined
      radionuclide and spin label study.
AB  - Single compartmental spherules of various lipid constituents (vesicles),
      enclosing (99m)TcO(4) (-) as a radioactive marker, were injected intravenously
      into C(3)H mice, and the distribution of radioactivity was studied. About 25% of
      the administered radioactivity was present in the liver 5 min and 30 min after
      the injection of vesicles composed of phosphatidylcholine and gangliosides, which
      were sonicated for 5 min (standard preparation). About 10-20% of the
      radioactivity remained in the circulation. By use of a nonradioactive spin label
      (tempocholine) enclosed within vesicles, intact vesicles were demonstrated in the
      circulation for 46 min after intravenous injection. The distribution of
      radioactivity from (99m)TcO(4) (-) inside vesicles is very different from that of
      free (99m)TcO(4) (-) or of (99m)Tc sulfur colloid. Increase in the length of
      sonication or incorporation of cholesterol into the wall of the vesicles enhanced
      hepatic levels and reduced blood levels of radioactivity. These same
      manipulations also slowed the rate of transfer of (99m)TcO(4) (-) out of vesicles
      in dialysis experiments in vitro. Addition of phosphatidic acid,
      phosphatidylethanolamine, or phosphatidylserine to the standard constituents did
      not greatly alter the distribution of radioactivity in vivo but did increase the
      number and type of active coupling sites on the outside of the vesicle. The
      results indicate that vesicles might be valuable as carriers of diagnostic or
      therapeutic agents.

PMID- 4372623
TI  - Sequence arrangements in clonal isolates of polyoma defective DNA.
AB  - Five clonal isolates of purified polyoma defective DNA [Fried, M. (1974) J.
      Virol. 13, 939-946] have been examined by electron microscopy. Four isolates (D
      92, D-74, D-50, and D-47) are largely homogeneous in sequence, whereas, the fifth
      isolate (D-80) is somewhat heterogeneous.Polyoma nondefective DNA is cleaved in a
      unique region of the genome by the EcoR(I) endonuclease. Hybridization of the
      resulting linear molecules with randomly nicked defective DNA reveals
      distinguishable types of heteroduplex structures for each of the different
      defective DNAs. Although the defective DNAs are shorter than polyoma nondefective
      DNA, the heteroduplex experiments demonstrate that they are not simply deletion
      mutants containing only a portion of the viral genome. Three isolates (D-92, D
      50, and D-47) contain regions of homology to polyoma DNA covalently linked to non
      homologous regions. One isolate (D-74) contained no regions of detectable
      homology to polyoma DNA. Another isolate (D-80) contained a large proportion of
      molecules with duplicated-inverted regions. Some of these isolates of defective
      DNA may contain specific host sequences at the site(s) of integration of the
      polyoma genome during the lytic cycle in mouse cells. A process we term "abortive
      replication" may explain the formation of different types of defective DNAs.

PMID- 4372624
TI  - AKR murine leukemia virus genome: frequency of sequences in DNA of high-, low-,
      and non-virus-yielding mouse strains.
AB  - Studies with a single-stranded DNA probe complementary to the RNA of mouse-tropic
      AKR murine leukemia virus indicate that the complete genome of the AKR-type
      murine leukemia virus is present in the DNA of high- and low-virus-yielding mouse
      strains, while DNA of non-virus-yielding strains contains only a part of the
      genome. Furthermore, in those strains where the genome is complete, two
      populations of virus-specific DNA sequences can be identified (more abundant and
      less abundant species) according to their rate of association with the probe. Low
      virus-yielding mouse strains contain fewer copies of the less abundant species
      and, consequently, fewer complete viral genomes than do high-virus-yielding
      strains. Thus, in the ten strains tested, there is a good correlation between
      completeness of the genome of AKR-type murine leukemia virus in cellular DNA and
      the capacity of the cells to release infectious AKR-type murine leukemia virus.
      Moreover, the number of complete viral genomes correlates with the frequency of
      infectious virus production by virus-positive strains. DNA from wild Mus musculus
      also contained viral sequences, the sample tested showing reassociation kinetics
      identical to the non-virus-producing strains.

PMID- 4372625
TI  - The nucleotide sequence complexity of avian tumor virus RNA.
AB  - The nucleotide sequence complexity of 60-70S RNA of Rous sarcoma virus was
      determined from the molar yields of 11 pure oligonucleotides of known chain
      length, obtained from [(32)P]RNA of Rous sarcoma virus by T1 RNase digestion and
      two-dimensional polyacrylamide gel electrophoresis. We calculate an apparent
      chain length of about 9800 nucleotides, corresponding to a molecular weight of
      3.4 x 10(6). Assuming the molecular weight of 60-70S RNA of Rous sarcoma virus to
      be about 10(7), our data suggest that the virus genome consists of identical, or
      very similar, nucleotide sequences repeated three to four times.

PMID- 4372626
TI  - Establishment of a clone of mouse hypothalamic neurosecretory cells synthesizing
      neurophysin and vasopressin.
AB  - Hypothalamic cells taken from 14-day-old mouse embryos were cultured for 6 days
      and transformed with simian virus 40. After cloning, a homogeneous cell
      population was obtained. Its morphological, Ultrastructural, biochemical, and
      immunochemical properties were studied. These cells possess ultrastructural
      features of primitive neurosecretory cells. They synthesize (35)S-labeled protein
      components that have the molecular weight and isoelectric focusing behavior of,
      and display the same immunoreactivity as, neurophysin. In addition, a (35)S
      labeled peptidic fraction with a molecular weight close to 1000 is synthesized
      and is radioimmunologically indistinguishable from vasopressin. Immunochemical
      staining shows that both neurophysin and vasopressin are localized in the
      cytoplasm. These observations strongly suggest that a clone of mouse hypothalamic
      neurosecretory cells has been obtained with the synthesizing capacities of
      secretory neurons of the magnocellular hypothalamic nuclei.

PMID- 4372627
TI  - Activation of protein kinase by physiological concentrations of cyclic AMP.
AB  - When determined under the usual conditions of an excess of ligand over protein,
      the concentration of cyclic AMP necessary to activate pure preparations of cyclic
      AMP-dependent protein kinase (EC 2.7.1.37; ATP:-protein protein
      phosphotransferase) half-maximally is in the range of 0.2-0.3 muM when casein or
      glycogen synthetase is used as the substrate, i.e., essentially the same as the
      concentration of the nucleotide that is found in resting skeletal muscle. The
      apparent dissociation constant for cyclic AMP bound to the protein kinase is also
      about 0.2-0.3 muM when measured under similar conditions. The concentration of
      the protein kinase in muscle is relatively high (0.23 muM), however, and under
      these conditions the apparent activation constant of the enzyme for cyclic AMP is
      raised so that an increase in cyclic AMP levels in the tissue would cause a
      concomitant increase in protein kinase activity over a wide range of nucleotide
      concentration. As a result, it is unnecessary to invoke compartmentalization of
      cyclic AMP to explain how it can control protein kinase activity in vivo. Another
      factor that may increase the effectiveness of changes in cyclic AMP concentration
      is the heat-stable protein inhibitor of protein kinase that may function to
      inhibit the activity of nearly all the protein kinase catalytic subunit
      dissociated by basal concentrations of cyclic AMP. Finally, the near equity
      between the concentration of cyclic AMP binding sites and the ligand itself
      provides a potential mechanism whereby agents can affect the total cyclic AMP
      content without directly affecting adenylate cyclase, cyclic AMP
      phosphodiesterase, or cyclic AMP transport.

PMID- 4372628
TI  - Collagenase production by endotoxin-activated macrophages.
AB  - Peritoneal exudate macrophages, when exposed to bacterial lipopolysaccharide in
      culture, were found to produce collagenase (EC 3.4.24.3). This enzyme was not
      detected in extracts of the macrophages or in media from nonstimulated macrophage
      cultures. Lipidcontaining fractions of the lipopolysaccharide, including a
      glycolipid from the rough mutant of Salmonella minnesota (R595) and lipid A, were
      potent stimulators of collagenase production. The lipid-free polysaccharide
      fraction had no effect. Cycloheximide prevented the production of collagenase by
      endotoxin-treated macrophages, suggesting that it was newly synthesized.

PMID- 4372629
TI  - Evidence for cholinergic synapses between dissociated rat sympathetic neurons in
      cell culture.
AB  - Sympathetic principal neurons were dissociated from superior cervical ganglia of
      new-born rats, and grown in cell culture. In electrophysiological experiments two
      types of excitatory synapses were found. One, which was relatively rare, was
      shown to operate by electrical transmission. The other, the predominant type, had
      several characteristics of chemical transmission, and pharmacological evidence
      indicated it was cholinergic.

PMID- 4372630
TI  - The primary structure of high density apolipoprotein-glutamine-I.
AB  - The major protein constituent of human plasma high density lipoproteins has been
      isolated and its complete amino-acid sequence determined. The protein, designated
      apolipoprotein-glutamine-I by the presence of carboxyl-terminal glutamine, is a
      single polypeptide chain of 245 amino-acid residues, including three residues of
      methionine. The protein is devoid of cysteine, cystine, and isoleucine. Cleavage
      of apolipoprotein-glutamine-I with cyanogen bromide yields four fragments with
      94, 90, 36, and 25 amino acids. The amino-acid sequence of each fragment was
      determined by conventional methods, with proteolytic digestion with trypsin,
      chymotrypsin, and thermolysin. The alignment of the cyanogen bromide fragments
      was determined by the isolation of the methionine-containing tryptic peptides
      from apolipoprotein-glutamine-I. Inspection of the sequence of apolipoprotein
      glutamine-I suggests an interesting distribution of amino acids that may account
      for its helical structure and its ability to bind and transport lipid.

PMID- 4372631
TI  - Host control of endogenous murine leukemia virus gene expression: concentrations
      of viral proteins in high and low leukemia mouse strains.
AB  - Two of the major molecular components of murine leukemia virus particles, the
      internal protein (p30) and the envelope glycoprotein (gp69/71) have been measured
      in the spleens of normal, 6- to 10-week-old mice of various inbred strains and
      crosses. Both proteins were detected in virtually all mice. Extracts of high
      leukemia, high murine leukemia virus strains (AKR, C58, PL) showed high levels of
      both proteins; extracts of other strains usually showed lower levels. Of
      particular interest, however, were the exceptions to these general observations:
      (1) Very little gp69/71 could be detected in spleens of BALB mice, and this trait
      was dominant in crosses with AKR and DBA/2, both of which express a high level of
      gp69/71. Thymus-deficient BALB/c-nu/nu (nude) mice, in contrast, showed a higher
      concentration of gp69/71 typical of other low leukemia strains, suggesting that
      the virtual absence of the protein in normal BALB/c mice may result from
      immunologic suppression. (2) With C57L, C57BL/10Sn, and C57BL/6 strains the
      concentration of p30 was lower, in some cases much lower, than would be expected
      from the concentration of gp69/71. (3) DBA/2 mice showed high levels of gp69/71,
      10-fold greater than that of p30, whereas congenic DBA/2-Fv-1(b) mice showed the
      opposite pattern. (4) Mice of 129-G(IX) (-) strain showed no detectable levels of
      either p30 or gp69/71 proteins, although the congenic 129 (G(IX) (+)) showed
      appreciable levels of both. The absence of these proteins in 129-G(IX) (-) mice
      is a recessive trait, as F(1) hybrids with AKR and DBA/2 showed appropriate
      levels of both proteins. It is concluded that expression of viral p30 and gp69/71
      proteins in mice is not coordinately linked and that expression is complex, being
      influenced by several genes, including Gv-1, H-2, Fv-1, and probably still
      others.

PMID- 4372632
TI  - Change in state of spin labels bound to sarcoplasmic reticulum with change in
      enzymic state, as deduced from ascorbate-quenching studies.
AB  - The ATPase (EC 3.6.1.3) of sarcoplasmic reticulum vesicles was reacted to various
      extents with thiol-directed spin labels. By suspension of the preparation in
      appropriate solutions, the enzyme could be placed and held in certain
      intermediate states of the ATPase cycle, or it could be set into steady-state
      catalysis. Ascorbate added to the system destroyed the spin-label signals with
      undetectable distortion of the electron paramagnetic resonance spectrum. In
      general, in the presence of ascorbate, undestroyed signal as a function of time
      could be described as the sum of two first-order reductions going on in separate
      compartments with different ascorbate concentrations. In different enzymatic
      states the proportion of total signal in the two compartments was different, but
      the first-order velocity constants remained the same. If the labeled membrane was
      first attacked with Triton, then exposed to ascorbate, signal was destroyed
      according to a single first-order constant, equal to the faster of the two
      constants observed with intact membrane, and equal to the constant whereby
      ascorbate attacks free label in solution. The data were reconciled by a simple
      rotary model, envisioning that an enzymatic state corresponds to an average
      angular position of the ATPase and thereby determines the proportion of labeled
      thiols exposed to external and internal ascorbate concentrations.

PMID- 4372633
TI  - 13C nuclear magnetic resonance spectroscopic evidence for hydrophobic lipid
      protein interactions in human high density lipoproteins.
AB  - Phosphatidylcholines, sphingomyelins, cholesterol, and cholesterol esters were
      enriched with (13)C by chemical synthesis in specific positions of their
      hydrophilic groups and aliphatic chains. Their spin-lattice relaxation times were
      determined in organic solvents. The substances were organized as liposomes and
      recombined with total human high density apolipoproteins and the two separated
      main components, apolipoprotein A-I (apoLp-Gln-I) and apolipoprotein A-II (apoLp
      Gln-II). These (13)C nuclear magnetic resonance data established that in
      reassembled high density lipoproteins the phospholipid molecules bind to the
      apoprotein moieties with their hydrophobic fatty acid chains and not with their
      hydrophilic zwitterionic groups. Apolipoprotein A-I preferentially binds
      phosphatidylcholine, although its lipid-binding capacity is smaller than that of
      apolipoprotein A-II. Apolipoprotein A-II avidly reassembles with sphingomyelin by
      hydrophobic interactions. A model of the molecular organization of the high
      density lipoportein particle has been derived.

PMID- 4372634
TI  - 13C nuclear magnetic resonance spectroscopy of native and recombined
      lipoproteins.
AB  - (13)C nuclear magnetic resonance data on native and recombined lipoproteins are
      reported. [Methyl-(13)C]phosphatidylcholine, [methyl-(13)C]sphingomyelin, 1,2
      [dioleoyl-1-(13)C]-sn-phosphatidylcholine and cholesteryl-[1-(13)C]oleate were
      enriched with 90% carbon-13 in respective molecules by chemical synthesis and
      used for recombination experiments with high density lipoprotein apoproteins.
      Relaxation times for these specifically enriched lipids in organic solvents,
      (2)H(2)O, and lipid-protein complexes isolated by ultracentrifugal flotation,
      were measured. The results show that both the phosphatidylcholine and
      sphingomyelin polar headgroups have the same hydrophilic environment in either
      sonicated lipid particles or reassembled lipoproteins, and suggest that ionic
      interaction of lipid and apolipoproteins is of minor importance in the formation
      of plasma lipoprotein complexes. Our experiments indicate that (13)C nuclear
      magnetic resonance spectroscopy will contribute to the understanding of
      lipidprotein interaction in lipoproteins and membranes.

PMID- 4372635
TI  - Type C viral expression in primate tissues.
AB  - Nucleic acid sequences homologous to a [(3)H]DNA transcript prepared from an
      endogenous baboon type C virus are readily detected in both the cellular DNA and
      RNA of several different Old World monkeys. Competitive radioimmunoassays for the
      major viral protein (p30) of baboon type C viruses detect viral antigen in a
      normal stumptail spleen and a rhesus ovarian carcinoma. The p30 antigen from
      these tissues is closely related by several immunologic criteria to the p30
      protein of baboon type C viruses. The results indicate that normal primate
      tissues transcribe endogenous viral-specific RNA and translate at least one viral
      structural protein.

PMID- 4372636
TI  - Simian virus 40 T antigen binds to DNA.
AB  - The T antigen of simian virus 40, which may play a role in the control of viral
      DNA replication, is recovered from nuclei of cells transformed by simian virus 40
      in several forms sedimenting at different rates. The large molecular weight forms
      are converted to the smallest (5 S) form by high salt, suggesting that they
      differ in the degree of aggregation. All the forms of the antigen bind
      efficiently to double-stranded DNA-cellulose columns at pH 6.2 and low salt, and
      elute in two fractions: one at pH 8.0 and low salt, the other at pH 8.0 and high
      salt. The antigen has little affinity for single-stranded DNA.

PMID- 4372637
TI  - Necrolytic migratory erythema with glucagon-secreting tumour of the pancreas.

PMID- 4372638
TI  - Diagnosis and management of insulinoma.

PMID- 4372639
TI  - Emiocytosis: a possible molecular mechanism.

PMID- 4372640
TI  - Antagonism of the dipsogenic action of intraseptal angiotensin II in the rat.

PMID- 4372641
TI  - Polypeptide influences on attention, memory and anxiety in man.

PMID- 4372642
TI  - Equilibrium between metabolic pathways producing energy: a key factor in
      regulating lipolysis.

PMID- 4372643
TI  - Cyclophosphates VI. Cyclophosphates as substrates and effectors of
      phosphodiesterase.

PMID- 4372644
TI  - Sodium preference induced by angiotensin in the rat.

PMID- 4372645
TI  - The concept of the quasi-abstinence effect and its use in the investigation of
      dependence mechanisms.

PMID- 4372647
TI  - Duration of paradoxical sleep necessary for the acquisition of conditioned
      avoidance in the rat.

PMID- 4372646
TI  - Effects of ACTH on conditioned suppression: a time and strength of conditioning
      analysis.

PMID- 4372648
TI  - Effect of daytime alpha rhythm maintenance on subsequent sleep.

PMID- 4372649
TI  - Heart rate levels of black and white newborns.

PMID- 4372650
TI  - Proceedings: Evolutionary role of neuromelanin.

PMID- 4372651
TI  - Proceedings: Drug and sociotherapy in the aftercare of schizophrenic patients.

PMID- 4372652
TI  - The effect of internally deposited plutonium-239 on the lysosomes of rat liver.

PMID- 4372653
TI  - The extraction of the yet unused wealth of information in diagnostic radiology.

PMID- 4372654
TI  - Adenohypophyseal function during cerebral angiography.

PMID- 4372655
TI  - [Mechanism of action of steroid hormones (author's transl)].

PMID- 4372656
TI  - [Regulation of hepatic fructose 1,6-diphosphatase--modification by an endogenous
      protease and the presence of the regulatory sulfhydryl groups (author's transl)].

PMID- 4372657
TI  - Prostaglandin-sepharose: application to the purification of bovine lung 15 (S) 
      hydroxyprostaglandin dehydrogenase.

PMID- 4372658
TI  - The hypothalamic "savage" syndrome.

PMID- 4372659
TI  - Inhibition of hepatic drug metabolism by cyclic 3',5'-adenosine monophosphate.

PMID- 4372660
TI  - Experimental sheep pox. A histological and ultrastructural study.

PMID- 4372661
TI  - Oestrogen excretion by sows with induced cystic ovarian follicles.

PMID- 4372662
TI  - Fluorescent antibody inhibition for determination of serum antibodies against the
      enterotoxin of Clostridium perfringens type A.

PMID- 4372664
TI  - Acute lymphoblastic leukemia of childhood: results of combination therapy.

PMID- 4372663
TI  - [Peripheral neuropathies in Waldenstrom's disease. 5 cases with ultrastructural
      study of the peripheral nerve].

PMID- 4372665
TI  - [Incidence, nature and development of liver tumors].

PMID- 4372666
TI  - [Primary cancers of the liver in adults and their treatment].

PMID- 4372667
TI  - [Benign tumors of the liver].

PMID- 4372668
TI  - [Malignant hepatoma in the African].

PMID- 4372669
TI  - [Primary tumors of the liver in children].

PMID- 4372670
TI  - [Intrasacral cysts (case report, review)].

PMID- 4372671
TI  - [Lumbar radiculalgia due to large canals. A variety of spino-radiculo-meningo
      vertebral dysharmony of duramatral origin].

PMID- 4372672
TI  - [Radioisotope scanning of the skeleton using Technetium 99m-labelled
      pyrophosphate; diagnosis of bone metastases].

PMID- 4372674
TI  - Emphysematous cholecystitis--an important clinical variant of acute
      cholecystitis.

PMID- 4372673
TI  - [Use of tetracosactine in rheumatoid arthritis associated with ulcerous
      gastritis].

PMID- 4372675
TI  - Studies on human serum high-density lipoproteins. II. Isolation of subfractions
      in the cold.

PMID- 4372676
TI  - Megaduodenum. A case with bacterial overgrowth, deconjugation of bile salts,
      malabsorption, and polyneuropathy.

PMID- 4372677
TI  - Ultrastructural changes in jejunal epithelial cells in liver cirrhosis.

PMID- 4372679
TI  - Adrenocortical function in children with juvenile rheumatoid arthritis and other
      connective tissue disorders.

PMID- 4372678
TI  - FL 1039 in bacteriuria following prostatectomy. A double-blind comparison with
      pivampicillin and placebo.

PMID- 4372681
TI  - [Diabetes insipidus--various recent aspects].

PMID- 4372680
TI  - [Catamnestic studies on the clinical characteristics of cylindroma].

PMID- 4372682
TI  - Reversal of catecholamine refractoriness by inhibitors of RNA and protein
      synthesis.
AB  - The generation of adenosine 3',5'-monophosphate (cyclic AMP) in response to
      catecholamines in the 2B subclone of RGC6 rat glioma cells previously exposed to
      norepinephrine and refractory to further norepinephrine addition is substantially
      increased by addition of inhibitors of RNA and protein synthesis. The time course
      of the effect of these inhibitors on cyclic AMP concentration suggests that rapid
      protein synthesis and turnover are involved in catecholamine refractoriness.
      Norepinephrine induction of cyclic nucleotide phosphodiesterase is demonstrable
      in RGC6 cells but not in the 2B subclone. Thus, catecholamine refractoriness
      cannot be attributed to induction of phosphodiesterase. This implies that
      induction of a protein or proteins, important in catecholamine refractoriness,
      affects the synthesis rather than the degradation of cyclic AMP.

PMID- 4372683
TI  - [Acute hemorrhagic gastrointestinal ulcers. Apropos of 100 cases].

PMID- 4372684
TI  - [Medical study of 62 duodenal ulcers treated by vagotomy and pyloroplasty].

PMID- 4372685
TI  - [Gastrointestinal hemorrhages under anticoagulant treatment].

PMID- 4372686
TI  - [Diffuse ischemic enterocolitides. Apropos of 2 cases].

PMID- 4372687
TI  - ["C-cell" thyroid adenoma revealed by chronic diarrhea].

PMID- 4372688
TI  - [Quantitative study of immunoglobulins in jejunal secretions and feces].

PMID- 4372689
TI  - [Hiatal hernia, mega-esophagus, esophageal fibromyoma, submucous lipoma of the 3d
      duodenum, and diverticulum of the duodenal window].

PMID- 4372690
TI  - [Peptic esophagitis and precancerous dysplasia. Apropos of a case].

PMID- 4372691
TI  - [False radiological picture of a tumor of the greater gastric tuberosity].

PMID- 4372692
TI  - [Voluminous niche of the small curvature and icterus due to retention].

PMID- 4372694
TI  - [Muco-erosive cancer (stage I). Early diagnosis by directed gastro-biopsy].

PMID- 4372693
TI  - [Ulcerated schwannoma of the large gastric tuberosity].

PMID- 4372695
TI  - [Degenerated ulcer of the small curvature].

PMID- 4372696
TI  - [Lymphocytic lymphosarcoma of the stomach].

PMID- 4372697
TI  - [Subserous schwannoma of the 2nd duodenum with tumoral and anemic
      symptomatology].

PMID- 4372698
TI  - [Double diverticulum of the Vaterian area simulating two postoperative ulcers
      following gastrectomy with gastroduodenal anastomosis].

PMID- 4372699
TI  - [Recurrent occlusion of the small intestine].

PMID- 4372700
TI  - [Serous cyst of the right mesocolon].

PMID- 4372701
TI  - [Rectal and cutaneous localizations of Abrikosoff's granulous cell tumor].

PMID- 4372703
TI  - [Pedicular cavernoma of the hepatic artery. Ostial stenosis of the celiac trunk
      and false cyst of the tail of the pancreas].

PMID- 4372702
TI  - [Hypersecreting, degenerated rectal villous tumor. Recurrence of pulmonary
      tuberculosis. Fibrous ileo-cecal tuberculosis].

PMID- 4372704
TI  - [Allergic echinococcic hepatitis].

PMID- 4372705
TI  - [Pseudocyst of the pancreas with intra-hepatic development].

PMID- 4372707
TI  - [Basilar impression and rheumatoid arthritis].

PMID- 4372708
TI  - [The intervestibular line. Study of its intracranial localization in relation to
      the aqueduct of Sylvius].

PMID- 4372706
TI  - [Choledocho-duodenal fistula].

PMID- 4372709
TI  - [Crowned odontoid apophysis. Apropos of the development mechanism of certain
      images of axis manifestations].

PMID- 4372710
TI  - [Value of frontal zonography in sacculoradiculography].

PMID- 4372711
TI  - [A form of mobile odontoid spontaneously stabilized by the fusion of the anterior
      arch of the atlas with the axis body].

PMID- 4372712
TI  - [Extrinsic allergic alveolitis. 2. Etiopathogenic aspects].

PMID- 4372713
TI  - [Problems raised by general surgical operation in patients with heart disease].

PMID- 4372714
TI  - [Diagnosis and treatment of acute intermittent porphyria].

PMID- 4372715
TI  - Leukemia and lymphoma in experimental and domestic animals.

PMID- 4372718
TI  - The West Philadelphia Community Mental Health Consortium in retrospect:
      supraprocess and infraprocess.

PMID- 4372717
TI  - Psychotherapy with donors and recipients of kidney transplants.

PMID- 4372716
TI  - Etiologic factors in autoimmune hemolytic anemia.

PMID- 4372719
TI  - Mental health counselors--new professionals? The NIMH pilot group ten years
      later.

PMID- 4372720
TI  - Behavioral effects of cortisol in man.

PMID- 4372721
TI  - "Delayed" iatrogenic diseases.

PMID- 4372722
TI  - Adenovirus type 11 epidemic conjunctivitis in Singapore.

PMID- 4372723
TI  - Epidemic haemorrhagic conjunctivitis associated with adenovirus type 11 in
      Taiwan.

PMID- 4372725
TI  - Axenic cultivation of four strains of Entamoeba histolytica from liver abscesses.

PMID- 4372724
TI  - Immunological tests in asymptomatic intestinal amoebiasis.

PMID- 4372726
TI  - Dynamics of activity of redox enzymes in ontogenesis of Colorado beetle
      (Leptinotarsa decemlineata Say).

PMID- 4372728
TI  - Oestrogen, headache and oral contraceptives.

PMID- 4372727
TI  - [Thrombocytopenia due to Novalgetol (sodium phenyl-dimethyl-pyrazolon-methyl
      aminomethane-sulfonate)].

PMID- 4372729
TI  - Cervical synovial sarcoma in a young boy.

PMID- 4372730
TI  - Liver aspiration cytology.

PMID- 4372731
TI  - Toxicity and carcinogenicity of some South African cycad (Encephalartos) species.

PMID- 4372732
TI  - Inflammatory carcinoma of the breast.

PMID- 4372733
TI  - Radiologically occult lung cancer. Report of 26 cases.

PMID- 4372734
TI  - Results of treating malignant melanoma intralymphatically with radioactive
      isotopes.

PMID- 4372735
TI  - Low cerebro-spinal fluid sugar associated with malignant glioma.

PMID- 4372736
TI  - Immune responses in patients with gliomas.

PMID- 4372737
TI  - Structural changes during preparation of autogenous venous grafts.

PMID- 4372739
TI  - X-ray diffraction analysis of quartz in lung tissue.

PMID- 4372738
TI  - [Prostaglandins and the digestive system organs].

PMID- 4372741
TI  - Antimicrobial therapy in experimental pseudomonas infection.

PMID- 4372740
TI  - Immunological responsiveness in rats infected with the Soehner-Dmochowski murine
      sarcoma virus (MSV-SD).

PMID- 4372742
TI  - [Place of Cromolyn (Lomudal, Intal, Aarane) in the treatment-plan for bronchial
      asthma].

PMID- 4372743
TI  - [Sleep disorders and their treatment].

PMID- 4372744
TI  - Effect of fulvine on pulmonary arteries and veins of the rat.

PMID- 4372745
TI  - Response of patients receiving high dose beclomethasone dipropionate.

PMID- 4372746
TI  - Enhancement of plasminogen activator by vasopressin and adrenaline: a role of
      cyclic AMP?

PMID- 4372747
TI  - Membrane fusion in the growth cone-microspike region of embryonic nerve cells
      undergoing axon elongation in cell culture.

PMID- 4372748
TI  - Fine structure of ocelli in sphinx moths.

PMID- 4372749
TI  - A preliminary report on complex fibrillar aggregates in the gill epithelium of
      Panulirus interruptus (Randall).

PMID- 4372751
TI  - Effects of dibutyryl cyclic AMP on carbohydrate and lipid metabolism.

PMID- 4372750
TI  - Crystalline inclusions in the pituitary gonadotrophs of estrogen-primed, spayed
      rhesus monkeys (Macaca mulatta).

PMID- 4372752
TI  - Obesity and pituitary lipolytic hormones.

PMID- 4372753
TI  - [Comparative electrophoretic studies on leishmanial parasites of cutaneous
      leishmaniasis of the new world and their relationships to Leishmania donovani and
      L. tropica (author's transl)].

PMID- 4372754
TI  - Adenosine kinase from normal mouse erythrocytes and from Plasmodium chabaudi:
      partial purification and characterization.

PMID- 4372755
TI  - [Enzymatic, electron microscopic and polarographic characteristics of isolated
      rat brain mitochondria. II. Effect of isolation media composition].

PMID- 4372756
TI  - [Frequency and significance of lymphoplasmocyte infiltration in human gliomas
      (author's transl)].

PMID- 4372757
TI  - [Functional evaluation of the diencephalo-prehypophysio-corticoadrenal axis in
      subjects with malignant neoplasms].

PMID- 4372758
TI  - The production of blood cell stasis and endothelial damage in the blood vessels
      of chick embryos treated with ultrasound in a stationary wave field.

PMID- 4372759
TI  - [Ultrasonics in radiotherapy: the planning of treatment and follow-up of its
      results].

PMID- 4372760
TI  - Cyclic 3',5'-AMP-stimulated and non-stimulated phosphorylation of protein
      fractions from rat-liver cell sap on incubation with (gamma-32P)ATP.

PMID- 4372761
TI  - (32P)phosphoryl transfer by endogenous protein kinase at the Ehrlich cell surface
      into extrinsic acceptor proteins.

PMID- 4372762
TI  - Active site phosphopeptides from pea seed nucleoside diphosphate kinase.

PMID- 4372763
TI  - Innervation of the detrusor muscle and urethra.

PMID- 4372764
TI  - Sphincter electromyography.

PMID- 4372765
TI  - Symposium on renal lithiasis. Renal lithiasis in review.

PMID- 4372766
TI  - Symposium on renal lithiasis. Medical evaluation of urolithiasis. Etiologic
      aspects and diagnostic evaluation.

PMID- 4372767
TI  - Symposium on renal lithiasis. Urinary tract infection and renal lithiasis.

PMID- 4372768
TI  - Genetic determinants of urologic disease.

PMID- 4372770
TI  - Studies on the nucleic acid metabolism of renal tumour cells in vitro.

PMID- 4372769
TI  - Secondary hyperparathyroidism in rats with experimentally induced pyelonephritis.

PMID- 4372771
TI  - Clostridial cystitis emphysematosa.

PMID- 4372773
TI  - [Examination of the middle ear with the aid of contrast media in chronic otitis
      media].

PMID- 4372772
TI  - Shedding patterns of herpes simplex virus and cytomegalovirus among chronic
      dialysis patients.

PMID- 4372774
TI  - [Otogenic thrombosis of the sigmoid sinus and the bulb of the jugular vein
      affecting the glossopharyngeal, vagus and accessory nerves].

PMID- 4372775
TI  - [Polypoid benign formations of the nasal septum].

PMID- 4372776
TI  - Spontaneous neoplasms in aging Gerbillinae. A summary of forty-four neoplasms.

PMID- 4372777
TI  - An indirect haemagglutination test for the detection and assay of antibody to
      infectious bovine rhinotracheitis virus.

PMID- 4372778
TI  - Recent studies with etamiphyllin camsylate.

PMID- 4372779
TI  - Airborne stability of swine vesicular disease virus.

PMID- 4372780
TI  - Interaction of phage P2 DNA with some fast-sedimenting host components during
      infection.

PMID- 4372782
TI  - Temperature-sensitive mutants of herpes simplex virus type 1: isolation,
      complementation and partial characterization.

PMID- 4372781
TI  - Phosphoproteins, structural components of rhabdoviruses.

PMID- 4372783
TI  - Control of transcription during the expression of the bluetongue virus genome.

PMID- 4372784
TI  - Polyoma virus proteins: a description of the structural proteins of the virion
      based on polyacrylamide gel electrophoresis and peptide analysis.

PMID- 4372785
TI  - Studies on the type C viral replication defect in MSV-transformed rat nonproducer
      variant clones.

PMID- 4372786
TI  - Cucumber mosaic virus-induced RNA polymerase: partial purification and properties
      of the template-free enzyme.

PMID- 4372787
TI  - Electron microscopic studies of temperature-sensitive mutants of herpes simplex
      virus type 1.

PMID- 4372788
TI  - The persistence and expression of virus-specific DNA in revertants of Rous
      sarcoma virus-transformed BHK-21 cells.

PMID- 4372789
TI  - Reversion and induction of Rous sarcoma virus expression in virus-transformed
      baby hamster kidney cells.

PMID- 4372790
TI  - Isolation and characterization of a large molecular-weight polypeptide of herpes
      simplex virus type 1.

PMID- 4372791
TI  - Glycoprotein fragment associated with vesicular stomatitis virus after
      proteolytic digestion.

PMID- 4372793
TI  - [Embryonal nephroma in an adult].

PMID- 4372792
TI  - [Glomus tumors].

PMID- 4372794
TI  - [Carcinogenic effect of DMBA in rats via transplacental exposure].

PMID- 4372795
TI  - [Nucleic acid and glycogen content in the rat liver in the process of
      hepatocarcinogenesis caused by diethylnitrosamine].

PMID- 4372796
TI  - [Combined action of benzidine and 2-naphthylamine].

PMID- 4372797
TI  - [Hemangiomas of the abdominal cavity organs in children (based on data from the
      Department of Pediatric Surgery of the Donetsk Medical Institute)].

PMID- 4372798
TI  - [Pathogenesis and morphology of primary liver cancer developing on a background
      of opisthorchiasis].

PMID- 4372800
TI  - [Pelvic lymphadenectomy in cancer of the rectum].

PMID- 4372799
TI  - [Relationship of chronic pancreatitis and cancer of the pancreas].

PMID- 4372801
TI  - [Study of the radical copolymerization of C14-acrylamide and of the incorporation
      of H3-thymidine in a rat fibroblast culture in the presence of an adenovirus
      infection].

PMID- 4372802
TI  - [Glomus tumor of the carotid gland].

PMID- 4372803
TI  - [Pathomorphological disorders of the nervous system in experimental renal
      insufficiency].

PMID- 4372804
TI  - [Characteristics of the mechanism of transmission of the pathogen in respiratory
      infections (review of the literature)].

PMID- 4372806
TI  - [Activity of cytochrome oxidase in the blood serum and urine in chronic
      glomerulonephritis].

PMID- 4372805
TI  - [Activity of certain enzymes of leukocytes in arteriosclerosis].

PMID- 4372807
TI  - [Current views of viral hemorrhagic fever].

PMID- 4372808
TI  - [I-131 absorption and perchlorate test in Klinefelter's syndrome].

PMID- 4372809
TI  - [Androgenic adrenocortical tumor].

PMID- 4372810
TI  - [Case of primary hepatic carcinoma].

PMID- 4372811
TI  - [Plasma renin activity and total peripheral resistance in chronic end-stage renal
      disease (author's transl)].

PMID- 4372812
TI  - Entero-bacterial formation of cyclohexylamine in rats ingesting cyclamate.

PMID- 4372813
TI  - Kinetic experiments on the synergistic effect of NADH on microsomal drug
      oxidation.

PMID- 4372815
TI  - Expression of Epstein-Barr viral capsid, complement fixing, and nuclear antigens
      in stationary and exponential phase cultures.
AB  - Three continuous lymphoblastoid cell lines, 2 productive of nucleocapsids and 1
      nonproductive line, were studied for their content of Epstein-Barr viral (EBV)
      antigens during transition from stationary to logarithmic phase growth. As a
      preliminary step, viable cells were separated from degenerating ones in
      discontinuous gradients of serum albumin. Viral capsid antigens were found in
      both living and dead cells of the 2 producer lines; however, complement fixing
      (CF) antigens and nuclear antigen were detected only in viable cell
      subpopulations. The content of antigen detectable in extracts of viable cells by
      complement fixation remained constant in replicating and resting cultures;
      further, all viable cells of the 3 lines demonstrated intranuclear antigen by
      anticomplement immunofluorescence in all stages of growth. In contrast, the
      proportion of cells with viral capsid antigen in the producer lines increased 7-
      to 24-fold following entry of resting populations into the phase of exponential
      growth.The results suggest that expression of viral capsid antigens is
      discontinuous and is initiated in response to events in log phase, possibly DNA
      synthesis or mitosis. Expression of the complement fixing and nuclear antigens in
      continuous in viable cells. These findings emphasize the intimate relationship of
      the CF and nuclear antigen to the transformed state and suggest that study of
      this antigen complex will shed light on the mechanisms of lymphocyte
      transformation by EBV.

PMID- 4372817
TI  - Growth hormone studies in patients with rheumatoid arthritis with or without
      glucocorticoid therapy.

PMID- 4372814
TI  - Commentary. EB virus, infectious mononucleosis, and cancer: the closing of the
      web.

PMID- 4372816
TI  - [Histochemical changes in experimental partially permanent ischemia of the cat
      pancreas].

PMID- 4372818
TI  - Measurement of human plasma renin substrate concentration by angiotensin I
      radioimmunoassay: a discussion of methodical problems.

PMID- 4372819
TI  - An evaluation of the diagnostic value of haptoglobin and transferrin levels in
      serum.

PMID- 4372820
TI  - [The influence of temperature on the determination of enzyme activities in human
      serum: glutamate dehydrogenase (author's transl)].

PMID- 4372821
TI  - [Quantitative immunological determination of aldolase isoenzymes in serum
      (author's transl)].

PMID- 4372822
TI  - [A mechanized competitive protein binding analysis for serum cortisol which
      avoids extraction with organic solvents (author's transl)].

PMID- 4372823
TI  - [Brief hydrolysis of oestriol conjugates from pregnancy urine (author's transl)].

PMID- 4372824
TI  - Comparative investigation on the activity of a synthetic corticotrophin (18
      ACTH). A clinical trial.

PMID- 4372825
TI  - [The effect of oral contraceptives on plasma renin activity and plasma renin
      substrate concentration (author's transl)].

PMID- 4372826
TI  - [The reaction of nitrite with pesticides. Formation, chemical properties and
      carcinogenic activity of the N-nitroso compound of the herbicide N-methyl-N'-(2
      benzothiazolyl)-urea (benzthiazuron) (author's transl)].

PMID- 4372827
TI  - Reaction of methyl methanesulphonate with nucleic acids of fetal and newborn rats
      in vivo.

PMID- 4372830
TI  - [Glucocorticoid activity in true eczema].

PMID- 4372828
TI  - [Morphogenesis and micromorphology of epithelial tumors of the kidney of
      nitrosomorpholine intoxicated rats. I. Induction and histology (author's
      transl)].

PMID- 4372829
TI  - [Fine structure of the tegument of cercariae of Schistosoma mansoni (author's
      transl)].

PMID- 4372831
TI  - [Kininase activity of blood in patients with disseminated neurodermatitis].

PMID- 4372833
TI  - Comparative study of the phosphatase activity in the semen of bovines (Bos
      bubalis and Bos taurus) in Egypt.

PMID- 4372834
TI  - Intracytoplasmic myocardial inclusions in chickens.

PMID- 4372832
TI  - [Morphognostic and multivariate-statistical methods for sex and race
      determination (author's transl)].

PMID- 4372835
TI  - [Epidemiology and etiology of bovine influenza. I. Occurrence and distribution of
      bovine adenoviruses, rhinoviruses, reoviruses, and parainfluenza 3 virus].

PMID- 4372836
TI  - [Epidemiology and etiology of bovine influenza. II. Association of bovine
      adenoviruses, rhinoviruses, reoviruses and parainfluenza 3 virus with bovine
      enzootic bronchopneumonia].

PMID- 4372837
TI  - Isolation, cultivation and characterization of a poxvirus from some horses in
      Kenya.

PMID- 4372838
TI  - Studies on bovine leukemia. I. Establishment of type C virus producing cell
      lines.

PMID- 4372839
TI  - [Puncture-cytological diagnosis of liver diseases].

PMID- 4372840
TI  - Insulin secretion in hyperlipoproteinemias.

PMID- 4372841
TI  - Letter: 'Latent type IV' hyperlipoproteinemia.

PMID- 4372842
TI  - An improved in vitro bioassay method for measuring luteinizing hormone (LH)
      activity using mouse Leydig cell preparations.

PMID- 4372843
TI  - Cyclic AMP in isolated corpora lutea of the rat: influence of gonadotrophins and
      prostaglandins.

PMID- 4372844
TI  - Pharmacological mediators in asthma.

PMID- 4372845
TI  - Effect of pinealectomy on the 3H-5HT uptake of mast cells in the thyroid gland of
      the rat.

PMID- 4372846
TI  - Progressive myoclonic epilepsy with Lafora's bodies. A clinico-pathological
      study.

PMID- 4372848
TI  - Effects of chloroquine on neurons of long-term cultures of peripheral and central
      nervous system. A light and electron microscope study.

PMID- 4372847
TI  - Histochemical changes in the rat spinal cord after exposure to 6
      aminonicotinamide.

PMID- 4372849
TI  - Morphological changes induced by ouabain in normal and neoplastic human glia in
      monolayer culture.

PMID- 4372851
TI  - Genetics and physiology of colour vision. II.

PMID- 4372850
TI  - Infantile neuroaxonal dystrophy or Seitelberger's disease. IV. Autonomic nervous
      system involvement: electron microscopic study in two siblings.

PMID- 4372852
TI  - Clinical aspects of neonatal hypoglycaemia.

PMID- 4372853
TI  - Repression of hyaluronidase in Streptococcus mitis, ATCC 903.

PMID- 4372854
TI  - The distribution of enzymes and bacteria in the small intestines of slaughter
      pigs.

PMID- 4372855
TI  - Induction of SV40-tumour immunity by SV40-transformed cells in diffusion
      chambers.

PMID- 4372856
TI  - Decreased oncogenic potential of SV40-transformed cells grown in diffusion
      chambers intraperitoneally.

PMID- 4372857
TI  - The effect of lithium on blood pressure and on plasma renin substrate and renin
      in rats.

PMID- 4372858
TI  - Effect of lithium on glucagon-stimulated cyclic AMP excretion in rats.

PMID- 4372859
TI  - Pepstatin: lack of inhibition of the human renin-angiotensinogen reaction.

PMID- 4372860
TI  - The relation of plasma renin activity to left ventricular hypertrophy and
      retinopathy in patients with arterial hypertension.

PMID- 4372861
TI  - Lp(a) lipoprotein and pre-beta1-lipoprotein in young adults.

PMID- 4372862
TI  - A theoretical treatment of the problem of virion attachment and infection of the
      host cell.

PMID- 4372863
TI  - Metabolic effect of interferon preparations and some interferon inducers:
      activation of adenylate cyclase system.

PMID- 4372864
TI  - Further evidences that priming is a non-antiviral function of interferon.

PMID- 4372865
TI  - "Plexiform vermicellar arrays" in human cytomegalovirus-infected WI-38 human
      embryonic fibroblast cells.

PMID- 4372866
TI  - [Tumours at the foramen magnum (author's transl)].

PMID- 4372867
TI  - [Results of ulnar nerve transposition. Demonstration of a postoperative
      compression syndrome].

PMID- 4372869
TI  - The rehabilitation of addicts.

PMID- 4372868
TI  - [Examination of tissue attached to ventricular catheters in mydrocephalic
      patients; light and electron microscopic study (author's transl)].

PMID- 4372870
TI  - The anion-binding functions of transferrin.

PMID- 4372871
TI  - Calcium binding to elastin.

PMID- 4372872
TI  - Cellular effects of lead.

PMID- 4372873
TI  - X-ray photoelectron spectroscopic studies of biological materials: metal ion
      protein binding and other analytical applications.

PMID- 4372874
TI  - The child with acute leukemia.

PMID- 4372875
TI  - Development of a dust sampling system for hardrock mines based on gravimetric and
      quartz assessment.

PMID- 4372876
TI  - X-ray diffraction determination of alpha-quartz in respirable and total dust
      samples from sand-blasting operations.

PMID- 4372877
TI  - Relationship between exposure to asbestos, collagen formation, ferruginous
      bodies, and carcinoma.

PMID- 4372878
TI  - Comparative evaluation of a partial thromboplastin reagent containing a non
      settling, particulate activator.

PMID- 4372879
TI  - Gastrointestinal malacoplakia. Report of a case and a review of the literature.

PMID- 4372881
TI  - Reappraisal of the role of insulin in hypertriglyceridemia.

PMID- 4372880
TI  - Immunoglobulin and autoantibody response in acute and chronic liver disease.

PMID- 4372882
TI  - The hormones of the hypothalamus.

PMID- 4372883
TI  - Hepatic abscess: changes in clinical, bacteriologic and therapeutic aspects.

PMID- 4372884
TI  - Fasting hypoglycemia, hypercalcemia and hyperprolactinemia. Multiple endocrine
      neoplasia, type 1?

PMID- 4372885
TI  - Parathyroid carcinoma in familial hyperparathyroidism.

PMID- 4372886
TI  - Breast cancer in men. Report illustrating the value of endocrine ablation.

PMID- 4372887
TI  - The "viruses of love" and cancer.

PMID- 4372888
TI  - Adenoid cystic carcinoma of the cervix presenting as a primary bronchial
      neoplasm.

PMID- 4372889
TI  - The use of a radioimmunoassay specific for human chorionic gonadotropin in
      patients with molar pregnancy and gestational trophoblastic disease.

PMID- 4372890
TI  - Ultrastructure of sclerosing hemangioma.
AB  - Specimens from 9 patients with the varying histopathologic patterns of sclerosing
      hemangioma were studied by electron microscopy. Not only were there numerous
      identifiable vascular spaces, but many of the cells had the ultrastructural
      characteristics of endothelial cells whether they were lining vascular spaces,
      forming organoid structures or were isolated. The Weibel-Palade bodies served as
      a marker for endothelial cells. They are rod-shaped, with a length up to 2 mu and
      a diameter up to .1 mu, and contain a tubular substructure, the diameter of the
      individual tubules being 150 [unk]. Our findings clearly support Gross and
      Wolbach's theory that this group of lesions is of endothelial origin.

PMID- 4372892
TI  - Male advancement in prenatal hand development.

PMID- 4372891
TI  - Experimental cytomegalovirus ophthalmitis.
AB  - Cytomegalovirus can produce a severe necrotizing chorioretinitis in patients on
      immunosuppressive therapy and infants born with congenital cytomegaloviral
      inclusion disease. To study the effect of cytomegalovirus on the eye, murine
      cytomegalovirus was injected into the eyes of nonimmunosuppressed Swiss CD-1
      weanling mice. The eyes were then prepared for virus titer, as well as light and
      electron microscopy at variable periods after inoculation (1 to 28 days). From
      days 2 to 6, the hallmarks of cytomegalovirus infection, intranuclear and
      intracytoplasmic viral inclusions, were evident within cytomegalic cells. The
      major site of reaction was in the uveal tract, where necrosis and inflammation
      were prominent. Viral particles budding through the nuclear membranes into the
      perinuclear cisternae and vacuoles with viral particles could be seen in the
      cytoplasm of infected cells. In lesions older than 2 weeks, only a mild mixed
      inflammatory infiltrate and fibrosis were observed. Morphologic alterations
      unaccompanied by inflammation occurred in the outer sensory retina overlying
      infected retinal pigment epithelial cells. Multiple necrotic foci with inclusion
      bearing cells in the liver indicated the systemic spread of virus from the eye.
      The titer of virus recovered from the eye peaked at day 4 and then declined to
      low levels, but infectious virus could still be isolated at day 28, even though
      viral particles were not seen morphologically at or after day 14. Many of the
      alterations seen in the model resemble those found in the human cytomegaloviral
      ophthalmitis.

PMID- 4372893
TI  - Carbohydrate metabolism of heat-acclimated hamsters. IV. Hormonal control.

PMID- 4372894
TI  - Effects of parathyroidectomy and cyclic AMP on renal transport of phosphate,
      calcium, and magnesium.

PMID- 4372895
TI  - Potassium deficiency in rats with hereditary diabetes insipidus.

PMID- 4372896
TI  - Relation of fibrinogen secretion (synthesis) to ACTH dose.

PMID- 4372897
TI  - ACTH stimulation of fibrinogen biosynthesis.

PMID- 4372898
TI  - Membrane depolarization, cyclic AMP, and glycerol release by brown adipose
      tissue.

PMID- 4372899
TI  - Catecholamine receptor function in depressed patients.

PMID- 4372900
TI  - Cultural aspects of psychotherapy.

PMID- 4372902
TI  - Artificial slow-flow carotid angiography with tumors of the glomus jugulare and
      of the carotid body.

PMID- 4372901
TI  - The use of multiple radionuclide imaging to differentiate the focal intrahepatic
      lesion.
AB  - Thirty-five patients with various focal intrahepatic lesions were evaluated with
      multiple radionuclides. Comparison of the blood pool scans with angiography and
      histology demonstrated an excellent correlation of these studies. Diagnostic
      accuracy was improved by separating the blood and pool scans into 3 categories.
      Each category suggested, at most, one further study to provide specific
      diagnostic information. Thus, by utilizing 3 radiopharmaceuticals, one can be
      more specific in preoperative diagnoses.

PMID- 4372903
TI  - In vitro cultivation of Plasmodium falciparum at high parasitemia.

PMID- 4372905
TI  - Correlation of circulating serum antibody to the histologic findings in breast
      cancer.

PMID- 4372904
TI  - Islet cell tumors of the pancreas.

PMID- 4372906
TI  - Clinical evaluation of the most frequently used analgetics: morphine, pethidine,
      pentazocine, fentanyl and noramidopyrine (pyralgin).

PMID- 4372908
TI  - Continuous pH-stat titration method for the assay of lipoprotein lipase activity
      in vitro.

PMID- 4372907
TI  - Determination of 5-phosphoribosyl 1-pyrophosphate in mouse liver.

PMID- 4372909
TI  - Identification of fatty acids by GC-MS using polar siloxane liquid phases.

PMID- 4372910
TI  - A new approach to the study of four nondepolarizing relaxants in man.

PMID- 4372911
TI  - The effect of ketamine on regional cerebral blood flow in man.

PMID- 4372912
TI  - Persistent viremia after regression of primary virus-induced feline
      fibrosarcomas.

PMID- 4372913
TI  - Duration of immunity in recycled turkey breeder hens vaccinated with a single
      dose of live avian encephalomyelitis virus vaccine.

PMID- 4372914
TI  - Early in utero infection of porcine embryos and fetuses with SMEDI (entero-)
      viruses: mortality, antibody development, and viral persistence.

PMID- 4372915
TI  - Pathogenic properties of six bovine picornavirus isolates in mice.

PMID- 4372916
TI  - Effects of cord factor on microsomal enzymes.

PMID- 4372917
TI  - Immune response in persistent infection. Further studies on persistent
      respiratory infection in man with para-influenza type 3 virus.

PMID- 4372918
TI  - Effect of angiotensin and ACTH on gastric secretion.

PMID- 4372919
TI  - Diagnostic value of thyrotrophin-releasing hormone in pituitary and hypothalamic
      diseases. Assessment of thyrotrophin and prolactin secretion in 100 patients.

PMID- 4372921
TI  - Emphysema, cirrhosis, and hepatoma with alpha-1 antitrypsin deficiency.

PMID- 4372920
TI  - Hepatocellular carcinoma and partial deficiency of alpha-1 antitrypsin (MZ).

PMID- 4372922
TI  - Letter: Parainfluenza virus type 3 isolated in a case of bloody diarrhea.

PMID- 4372923
TI  - Digitonin as an uncoupler of the partial reactions of Na+, K+-ATPase.

PMID- 4372924
TI  - Analysis of Na+, K+ and nucleotide interactions in terms of a heterotropic
      relaxation model for (Na+-K+)-ATPase.

PMID- 4372925
TI  - Studies of the effects of 2H2O on Na+, K+-ATPase.

PMID- 4372926
TI  - The relationship of the K+-activated phosphatase to the Na+,K+-ATPase.

PMID- 4372927
TI  - The effects of Ca2+ on ATPase and phosphatase activities of erythrocyte
      membranes.

PMID- 4372928
TI  - The effects of antibodies to Na+, K+-ATPase on the reactions catalyzed by the
      enzyme.

PMID- 4372929
TI  - Na+, K+ exchange and Na+, Na+ exchange in the giant axon of the squid.

PMID- 4372930
TI  - Action of methanethiol on Na+, K+-ATPase: implications for hepatic coma.

PMID- 4372931
TI  - Mechanism of the effects of lipid phase transitions on the Na+, K+-ATPase, and
      the role of protein conformational changes.

PMID- 4372932
TI  - Ouabain sensitivity of the Na+, K+-ATPase from rat neonatal and human fetal and
      adult heart.

PMID- 4372933
TI  - [Urinary excretion of total estrogens after administration of ACTH to pregnant
      women in the 3d trimester].

PMID- 4372934
TI  - [Comparison of results of arterial lipoid hepatography with those of liver
      scintigraphy using 99mTc sulfocolloids].

PMID- 4372935
TI  - Antibody levels to multiple viral antigens in systemic lupus erythematosus and
      some other connective tissue diseases.

PMID- 4372936
TI  - Regulation of enzyme activity during differentiation in Dictyostelium discoideum.

PMID- 4372937
TI  - Inclusion bodies of prokaryotes.

PMID- 4372938
TI  - Slow virus diseases.

PMID- 4372939
TI  - Cyclic AMP in prokaryotes.

PMID- 4372940
TI  - [Action of an organochlorine pesticide, the ddt, on the indifferentiated gonads
      in the bird embryo (author's transl)].

PMID- 4372941
TI  - [The thymus of human neonate and its perivascular channels. Ultrastructural study
      (author's transl)].

PMID- 4372942
TI  - Studies on photosystem I. Characteristics of "310 material" isolated from spinach
      chloroplasts.

PMID- 4372943
TI  - Metabolism of vitamin D3 in the chick embryo.

PMID- 4372944
TI  - Effect of trypsin, phospholipases, and membrane-impermeable reagents on the
      uptake of palmitic acid by isolated rat liver cells.

PMID- 4372945
TI  - Biosynthesis of myo-inositol in rat mammary gland. Isolation and properties of
      the enzymes.

PMID- 4372946
TI  - The effect of trypsin treatment on rabbit muscle phosphofructokinase.

PMID- 4372948
TI  - A two-step procedure for purification of papain from extract of papaya latex.

PMID- 4372947
TI  - A new ternary complex between horse liver alcohol dehydrogenase, NAD+, and
      acetone.

PMID- 4372949
TI  - Distribution of liver plasma membrane 5' nucleotidase as indicated by its
      reaction with anti-plasma membrane serum.

PMID- 4372950
TI  - Analysis of the ATP-induced conformational changes in sarcoplasmic reticulum.

PMID- 4372951
TI  - The reversal of experimental porphyria and the prevention of induction of hepatic
      mixed-function oxidase by acetate.

PMID- 4372953
TI  - In vivo changes of cellulose, trehalose and glycogen during differentiation of
      Dictyostelium discoideum.

PMID- 4372952
TI  - Studies on a HCO3 minus-stimulated ATPase and carbonic anhydrase system in rat
      liver lysosomes.

PMID- 4372954
TI  - Growth in children with 45,XO Turner's syndrome.

PMID- 4372956
TI  - Dose-response basis for settling a quartz threshold limit value: a new, simple
      formula for calculating the "lifetime dose" of quartz.

PMID- 4372955
TI  - Plasma renin activity in acute poststreptococcal glomerulonephritis and the
      haemolytic-uraemic syndrome.

PMID- 4372957
TI  - [Comparative study on the ultrastructure of Entamoeba Moshkovskii, parasitic
      amoebae of the genus Entamoeba, and free-living amoebae of the Hartmanella
      Naegleria group].

PMID- 4372958
TI  - Studies on some pathogenic strains of free-living amoebae isolated from lakes in
      Poland.

PMID- 4372959
TI  - [Immunosuppressive agents and aquatic amoebae].

PMID- 4372960
TI  - Clinical application of cytochrome a(plus a3) assay of mitochondria from liver
      specimens: an aid in determining metabolic tolerance of liver remnant for hepatic
      resection.
AB  - Measurement of cytochrome a(+a(3)) contents in liver mitochondria was made on 52
      biopsy specimens of patients with liver tumor. Patients having higher cytochrome
      a(+a(3)) contents in mitochondria from remaining liver than those of normal human
      liver mitochondria could survive well major liver resections whether or not
      associated with liver cirrhosis. However, patients with cytochrome a(+a(3))
      contents less than 0.5 x 10(-10) moles per mg protein showed a high rate of
      postoperative complication (80%) and death (40%) in spite of minor operation. In
      routinely used liver function tests such as serum albumin, A/G ratio, SGOT, total
      bilirubin, prothrombin time, BSP and TTT, there were no significant differences
      between patients with cytochrome a(+a(3)) contents more than 0.5 x 10(-10) moles
      per mg protein and those less than 0.5. The results indicate that routine
      laboratory studies do not have much diagnostic value in estimation of a marked
      decrease of mitochondrial cytochrome a(+a(3)) contents. It is suggested that the
      measurements of cytochrome a(+a(3)) of the remnant liver should be done prior to
      a contemplated major resection.

PMID- 4372962
TI  - Chemotherapy for adenocarcinoma and alveolar cell carcinoma of the lung.

PMID- 4372961
TI  - The role of early open lung biopsy in the diagnosis and treatment of Pneumocystis
      carinii pneumonia.

PMID- 4372964
TI  - [Sudden death with extraordinary patho-anatomical findings].

PMID- 4372963
TI  - Hydrocortisone suppression test for Cushing syndrome. Therapy with
      anticonvulsants.

PMID- 4372965
TI  - Nitrogen metabolism and ultrastructure in Anabaena cylindrica. II. The effect of
      molybdenum and vanadium.

PMID- 4372966
TI  - A study of sporophore development in the myxomycete Protophysarum phloiogenum.

PMID- 4372967
TI  - Hyphal tips of wild-type and spreading colonial mutants of Neurospora crassa.

PMID- 4372968
TI  - [Further investigation to the immunology of murine mammary tumours of the CBA-Bln
      strain using the colony inhibition tests (author's transl)].

PMID- 4372970
TI  - Quantitative studies by electron microscopy on the sex-difference and the change
      during the oestrous cycle in the mouse anterior pituitary.

PMID- 4372969
TI  - [Oncogen infectious nucleoproteid from "statu nascendi" stages of cervical cancer
      and herpes virus hominis (author's transl)].

PMID- 4372971
TI  - [Adsorption of homologous PEG and PEG derivatives on colloidal silica (author's
      transl)].

PMID- 4372973
TI  - [Ultrastructural changes in the organ of Corti after acute acoustic trauma].

PMID- 4372972
TI  - [Development of the interalveolar septa in rats during the postnatal period].

PMID- 4372974
TI  - [Myoepetelial adenoma. Histological and clinical aspects (author's transl)].

PMID- 4372975
TI  - Opsoclonus associated with an intracranial tumor. A clinicopathologic case
      report.

PMID- 4372976
TI  - Pullularia corneal ulcer.

PMID- 4372977
TI  - Xerosialography.

PMID- 4372978
TI  - Granular cell myoblastoma of the trachea.

PMID- 4372979
TI  - Fibrous histiocytomas of the nose and paranasal sinuses.

PMID- 4372981
TI  - Regional odontodysplasia. A review and a report of two cases.

PMID- 4372980
TI  - [Unilateral vestibular paralysis of toxoplasmosis (author's transl)].

PMID- 4372982
TI  - inositol phosphate phosphatases of microbiological origin. Some properties of the
      partially purified phosphatases of Aspergillus ficuum NRRL 3135.

PMID- 4372983
TI  - Preparation of fowl pox vaccine on chicken-embryo-dermis cell culture.

PMID- 4372984
TI  - Interferon production by strains of herpesvirus associated with Marek's disease.

PMID- 4372985
TI  - Factors influencing growth of Mycoplasma synoviae.

PMID- 4372987
TI  - [Isolation of foot-and-mouth-disease virus from organs of infected, slaughtered
      sheep].

PMID- 4372986
TI  - The limbic system: an interface.

PMID- 4372988
TI  - A new method for propagation of HVJ (Sendai virus) in vitro: high sensitivity and
      productivity in spreading cultures of fragmented chorioallantoic membrane of
      chick embryos.

PMID- 4372989
TI  - Chemical and immunological studies of liver microsomes from mouse mutants with
      ultrastructurally abnormal hepatic endoplasmic reticulum.

PMID- 4372990
TI  - Anti-anabolic effects of adenosine 3':5'-cyclic monophosphate. Inhibition of
      protein synthesis.
AB  - 1. Evidence is presented that cyclic AMP inhibits the incorporation of l-[4,5
      (3)H]leucine into protein in a cell-free system from rat liver. This inhibition
      occurs after aminoacyl-tRNA formation. 2. Microsomal fractions, isolated after
      the incubation of postmitochondrial supernatant with cyclic AMP and ATP, show a
      diminished ability to synthesize protein. Both cyclic AMP and ATP are required
      for this effect. 3. A possible physiological role for the anti-anabolic action of
      cyclic AMP is discussed in terms of the control of gluconeogenesis.

PMID- 4372992
TI  - The effects of acetylcolletotrichin on the mitochondrial respiratory chain.
AB  - 1. Acetylcolletotrichin is a phytotoxic compound that has been isolated from the
      culture medium of the fungus Colletotrichum capsici (Grove et al., 1966). 2. With
      isolated liver and kidney mitochondria acetylcolletotrichin markedly inhibited
      the oxidation of succinate and those substrates with NAD-linked dehydrogenases,
      but did not inhibit the oxidation of ascorbate in the presence of tetramethyl-p
      phenylenediamine. In this respect its action was similar to that of antimycin A.
      3. Acetylcolletotrichin differed from antimycin in that, even at high
      concentrations which produced a maximal inhibitory effect, its action was
      partially reversed by uncoupling agents. Also acetylcolletotrichin had no
      detectable effect on the oxidative activity of blowfly flight-muscle mitochondria
      and was not very effective with heart mitochondria. 4. Acetylcolletotrichin
      inhibited the oxidative activity of liver mitochondria more markedly when
      respiration was stimulated by ADP together with phosphate and was less effective
      when respiration was stimulated by uncoupling agents. 5. There was an unusual
      interaction between the succinate oxidation system and the oxidation of glutamate
      together with malate. Thus, glutamate together with malate, even in the presence
      of rotenone, markedly decreased the effectiveness of acetylcolletotrichin in
      inhibiting succinate oxidation. 6. These effects were paralleled in the observed
      redox changes of cytochrome c. 7. The unusual behaviour of the cytochromes b in
      the presence of acetylcolletotrichin is described, and it is suggested
      tentatively that this inhibitor acts between cytochromes b with absorption maxima
      at 30 degrees C of approximately 560 and 565nm.

PMID- 4372991
TI  - Nitrogen metabolism in the isolated perfused rat liver. Nitrogen balance, redox
      state and rates of proteolysis.
AB  - Nitrogen balances were measured in isolated perfused rat livers in the presence
      and absence of nitrogen donors. In all instances the balance apparently was
      incomplete. The expression [alanine][alpha-oxoglutarate]/[pyruvate][glutamate]
      remained fairly constant under the metabolic conditions studied, indicating that
      it may be at near-equilibrium. The source of the extra nitrogen seems to be
      derived from increased hepatic proteolysis. The addition of a nitrogen donor to
      the perfusate arrested proteolysis, as did the addition of pyruvate. The free
      mitochondrial [NAD(+)]/[NADH] ratio, calculated from the glutamate dehydrogenase
      and beta-hydroxybutyrate dehydrogenase reactants, showed similar values and
      exhibited parallel changes under most metabolic situations studied. These results
      suggest that, under the reported experimental conditions, both dehydrogenases
      share a common mitochondrial NAD pool. Glutamate dehydrogenase plays an important
      role in hepatic nitrogen metabolism in vivo.

PMID- 4372993
TI  - Biochemical effects of diquat and paraquat. Disturbance of the control of
      corticosteroid synthesis in rat adrenal and subsequent effects on the control of
      liver glycogen utilization.
AB  - 1. Administration of diquat (NN'-ethylene-2,2'-bipyridilium) or paraquat (NN'
      dimethyl-4,4'-bipyridilium) prevents the normal depletion of liver glycogen in
      starved rats. 2. There is an increase in blood glucose, which returns to normal
      values after approx. 7h. 3. After administration of diquat or paraquat, plasma
      corticosteroids increase to very high concentrations and remain high for at least
      24h, but plasma ACTH (adrenocorticotrophin) is only increased for 4h. 4. Adrenal
      cyclic AMP is considerably increased after administration of diquat and remains
      significantly higher than control values for at least 24h. 5. It is suggested
      that diquat and paraquat increase the response of the adrenal cortex to ACTH.

PMID- 4372994
TI  - Phosphodiesterases in human tissues. I. Identification and separation of enzymes
      active on bis(p-nitrophenyl)phosphate.

PMID- 4372995
TI  - Phosphodiesterases in human tissues. II. Decreased hydrolysis of synthetic
      substrate by tissues from patients with the Niemann-Pick syndrome.

PMID- 4372997
TI  - UDP glucose-4 epimerase from Saccharomyces fragilis: interaction with sugar
      phosphates at an effector site.

PMID- 4372996
TI  - Role of superoxide radical in mitochondrial dehydrogenase reactions.

PMID- 4372998
TI  - Insulin degradation in insulinoma: evidence for the occurrence of an inactive
      form of glutathione-insulin transhydrogenase and for the absence of insulin A and
      B chains degrading protease(s).

PMID- 4373000
TI  - The meta-cleavage of catechol by a thermophilic Bacillus species.

PMID- 4372999
TI  - Maintenance of the energy charge in the presence of large decreases in the total
      adenylate pool of Escherichia coli and concurrent changes in glucose-6-p,
      fructose-p2 and glycogen synthesis.

PMID- 4373001
TI  - Protein kinase activities during maturation in Xenopus laevis oocytes.

PMID- 4373003
TI  - Effects of methadone on steroid biosynthesis in rat adrenocortical cells.

PMID- 4373002
TI  - Commentary. Insulin receptors, cell membranes and hormone action.

PMID- 4373004
TI  - Hormone and adenosine 3', 5' cyclic monophosphate stimulated phosphorylation of
      human erythrocyte membranes.

PMID- 4373005
TI  - The occurrence of an inhibitor of lipid peroxidation in rat liver soluble
      fraction and its effect on microsomal drug oxidations.

PMID- 4373006
TI  - Lack of correlation between cyclic AMP synthesis and free fatty acid release in
      brown fat of cold-adapted rats.

PMID- 4373007
TI  - Papaverine-induced changes in cultured human melanoma cells.

PMID- 4373008
TI  - Rabbit testicular capsular contractions--prostaglandins, cyclic adenosine 3',5'
      monophosphate and epinephrine.

PMID- 4373009
TI  - Acinomycin D and purine transport in cultured rat hepatoma cells.

PMID- 4373010
TI  - Inhibition by papaverine of cGMP and cAMP phosphodiesterases from the rat heart.

PMID- 4373011
TI  - Apomorphine-induced accumulation of cyclic AMP in isolated retinas of the rabbit.

PMID- 4373013
TI  - On the absorption, excretion and metabolism of pentaerythritoltetranicotinate.

PMID- 4373014
TI  - [Behavior of the salivary electrolytes potassium and calcium in digitalized
      patients following administration of diphenylhydantoin].

PMID- 4373012
TI  - The role of basic substances of high molecular weight in the generalized
      Shwartzman reaction (GSR).

PMID- 4373015
TI  - [Sensitivity range of gram-negative microorganisms and mycoplasms to minocycline
      in vitro].

PMID- 4373016
TI  - The effect of glibenclamide on two enzymes important in gluconeogenesis.

PMID- 4373017
TI  - The effect of niceritrol (pentaerythritoltetranicotinate) and clofibrate upon
      hyperlipemia and atherosclerosis induced in rabbits by cholesterol-free
      semisynthetic diets.

PMID- 4373018
TI  - Action of niceritrol (pentaerythritoltetranicotinate) on lipid accumulation in
      aortas of cholesterol-fed rabbits independent of contemporary reduction of serum
      lipids.

PMID- 4373019
TI  - The pituitary melanotrophic hormones.

PMID- 4373020
TI  - [99m Tc Sn-pyrophosphate complex as a bone gammography agent in children].

PMID- 4373021
TI  - [Indications of glucocorticoids in pediatric nephrology].

PMID- 4373022
TI  - Laryngeal paralysis due to peripheral nerve damage.

PMID- 4373023
TI  - Histochemical and biochemical studies in ultraviolet irradiated tissue culture.

PMID- 4373024
TI  - Differential effects of propranolol on heart rate and plasma renin activity in
      patients treated with minoxidil.

PMID- 4373025
TI  - Experiments with human papilloma virus in cell culture.

PMID- 4373027
TI  - Calcium-binding protein and vitamin D metabolism in experimental protein
      malnutrition.

PMID- 4373026
TI  - Cytochemical demonstration of dihydrofolate reductase activity.

PMID- 4373028
TI  - A comparative electron spin resonance study of the erythrocyte membrane in
      myotonic muscular dystrophy.

PMID- 4373029
TI  - A predictable modification of enzyme specificity. Selective alteration of DNA
      bases by metal ions to promote cleavage specificity by deoxyribonuclease.

PMID- 4373030
TI  - Purification and properties of a neutral protease from rat liver chromatin.

PMID- 4373031
TI  - The separation, purification, and characterization of ethanolamine kinase and
      choline kinase from rat liver.

PMID- 4373032
TI  - Molecular kinetics of beef heart lactate dehydrogenase.

PMID- 4373033
TI  - A spin-label study of energy-coupled active transport in Escherichia coli
      membrane vesicles.

PMID- 4373034
TI  - Purification and characterization of adenosine-adenosine cyclic 3',5'
      monophosphate binding protein factors from rabbit erythrocytes.

PMID- 4373035
TI  - Thermodynamic relationships between the mitochondrial oxidation-reduction
      reactions and cellular ATP levels in ascites tumor cells and perfused rat liver.

PMID- 4373036
TI  - The kinetics of oxidation of reduced cytochrome c by ferricyanide derivatives.

PMID- 4373037
TI  - Studies on polynucleotides containing hybrid sequences. Synthesis of
      oligonucleotides possessing a single ribonucleotidyl-(3'-5')-deoxyribonucleotide
      linkage.

PMID- 4373038
TI  - Cylic adenosine 3',5'-monophosphate responses to concanavalin A in human
      lymphocytes. Evidence that the response involves specific carbohydrate receptors
      on the cell surface.

PMID- 4373039
TI  - Chloroacetaldehyde-modified dinucleoside phosphates. Dynamic fluorescence
      quenching and quenching due to intramolecular complexation.

PMID- 4373040
TI  - The mode of interaction of mitomycin C with deoxyribonucleic acid and other
      polynucleotides in vitro.

PMID- 4373041
TI  - Inhibitory effect of complex formation with oligodeoxyribonucleotide ethyl
      phosphotriesters on transfer ribonucleic acid aminoacylation.

PMID- 4373042
TI  - Lipid interactions in membranes of extremely halophilic bacteria. I. Electron
      spin resonance and dilatometric studies of bilayer structure.

PMID- 4373043
TI  - Lipid interactions in membranes of extremely halophilic bacteria. II.
      Modification of the bilayer structure by squalene.

PMID- 4373044
TI  - Studies on motional characteristics and distribution of protonated and anionic
      forms of spin-labeled 2,4-dinitrophenol in phospholipid bilayer membranes.

PMID- 4373045
TI  - 25-Hydroxyvitamin D3-1-hydroxylase. Inhibition in vitro by rat and pig tissues.

PMID- 4373046
TI  - Interaction of glycyl-L-phenylalanine with Escherichia coli phenylalanyl-tRNA
      synthetase.

PMID- 4373047
TI  - Inhibition of phosphodiesterases from Bacillus subtilis by nucleoside
      triphosphates.

PMID- 4373048
TI  - The interaction of thrombin and heparin. Proflavine dye binding studies.

PMID- 4373049
TI  - Biosynthesis of cholestanol: conversion of cholesterol into 4-cholesten-3-one by
      rat liver microsomes.

PMID- 4373050
TI  - Formation of polyprenol monophosphate glucose in Shigella flexneri.

PMID- 4373051
TI  - Diol lipids. XXVI. Identification of a threo-butane-2,3-diol phospholipid from
      Actinomyces olivaceus.

PMID- 4373052
TI  - In vitro incorporation of (3H)serine into phospholipids of proliferating and
      calcifying epiphyseal cartilage and liver.

PMID- 4373053
TI  - Changes in the phospholipid composition in the differentiating cellular slime
      mold, Dictyostelium discoideum.

PMID- 4373054
TI  - Interaction by sonication of C-apolipoproteins with lipid: an electron
      microscopic study.

PMID- 4373055
TI  - Lung-toxic furanoterpenoids produced by sweet potatoes (Ipomoea batatas)
      following microbial infection.

PMID- 4373056
TI  - Preparative isoelectric focusing of human serum high-density lipoprotein (HDL3).

PMID- 4373057
TI  - The action of protamine on clearing factor lipase and on plasma triglyceride
      metabolism.

PMID- 4373058
TI  - Composition and synthesis of gangliosides in mammary gland and milk of the
      bovine.

PMID- 4373059
TI  - Biosynthesis of diglyceride from phosphatidic acid in the membranes of Bacillus
      subtilis.

PMID- 4373060
TI  - Theoretical analysis of the molecular motion of spin labels in membranes. ESR
      spectra of labeled Bacillus subtilis membranes.

PMID- 4373061
TI  - Effect of ATP on the intermediary steps of the reaction of the (Na+ plusK+)
      dependent enzyme system. III. Effect on the p-nitrophenylphosphatase activity of
      the system.

PMID- 4373063
TI  - Flash photolysis-electron spin resonance study of the effect of o-phenanthroline
      and temperature on the decay time of the ESR signal B1 in reaction-center
      preparations and chromatophores of mutant and wild strains of Rhodopseudomonas
      spheroides and Rhodospirillum rubrum.

PMID- 4373062
TI  - The photo-oxidation of horse heart cytochrome c and native cytochrome c2 by
      reaction centres from Rhodopseudomonas spheroides R26.

PMID- 4373064
TI  - A new EPR-detectable component in the ubiquinol-cytochrome c reductase segment of
      the respiratory chain.

PMID- 4373065
TI  - Further characterization of a photosystem-II particle isolated from spinach
      chloroplasts by triton treatment: the reaction-center components.

PMID- 4373066
TI  - Separation of isozymes of horse liver alcohol dehydrogenase and purification of
      the enzyme by affinity chromatography on an immobilized AMP-analogue.

PMID- 4373067
TI  - Isolation of angiotensin-converting enzyme without kininase activity from hog and
      guinea pig plasma.

PMID- 4373068
TI  - An enzyme thermistor.

PMID- 4373069
TI  - Conversion of UDP-D-glucuronic acid to UDP-D-apiose and UDP-D-xylose by an enzyme
      isolated from Lemna minor.

PMID- 4373071
TI  - Pigeon liver diacetyl reductase. Kinetic and thermodynamic studies with NADH as
      coenzyme.

PMID- 4373070
TI  - The nature of modifications by various anions of synthetic and hydrolytic
      activities of multifunctional glucose-6-phosphatase.

PMID- 4373072
TI  - Molecular weight determinations of hydrophilic proteins by cationic detergent
      electrophoresis. Application to membrane proteins.

PMID- 4373073
TI  - Non-specific protein binding by adsorbents designed for the specific affinity
      chromatography of sialidase in crude bacterial extracts.

PMID- 4373075
TI  - Isolation of the Ochromanas danica plasma membrane and identification of several
      membrane enzymes.

PMID- 4373074
TI  - The intermolecular cross-links in rat uterine collagen.

PMID- 4373076
TI  - Pressure-induced elevation of phase transition temperature in
      dipalmitoylphosphatidylcholine bilayers. An electron spin resonance measurement
      of the enthalpy of phase transition.

PMID- 4373077
TI  - The size of the repeating unit of the repetitive mitochondrial DNA from a "low
      density" petite mutant of yeast.

PMID- 4373078
TI  - Preparation and properties of poly(5-ethylcytidylic acid), a poly(5
      methylcytidylic acid) analogue.

PMID- 4373079
TI  - Ribonuclease and phosphodiesterase activities in rat hepatocyte plasma membranes.

PMID- 4373080
TI  - Multiple mechanisms of regulation of purine biosynthesis de novo in intact tumor
      cells.

PMID- 4373082
TI  - [Calorimetric study of the heat denaturation of cytochrome C].

PMID- 4373081
TI  - Regulation of N-acetylglucosamine kinase synthesis in yeast.

PMID- 4373083
TI  - [Letter: Photosensitized formation of atomic hydrogen in aqueous solutions of
      dimethylformamide and protein].

PMID- 4373084
TI  - [Letter: Change in the free radical concentration in rat internal organ tissues
      following administration of DMBA and its noncarcinogenic analog].

PMID- 4373085
TI  - [Formation and transformation of free radicals in frozen aqueous solutions of
      proteins, irradiated with UV-rays].

PMID- 4373086
TI  - [Spectral study of ion-radical forms of Mg-etioporphyrin].

PMID- 4373088
TI  - A molecular orbital treatment of Cu(II) proteins.

PMID- 4373087
TI  - [Ultrastructural organization of cytochrome c-phospholipid complexes].

PMID- 4373090
TI  - [Nonclassical state of the neuron].

PMID- 4373089
TI  - [Current aspects of hormonal interactions at the level of plasma membranes in
      gastrointestinal tissue and in the liver].

PMID- 4373091
TI  - Immunological stimulation with modified cancer cells.

PMID- 4373092
TI  - Adrenocortical steroidogenesis and aminoglutethimide (A. G.). II. Cytochemical
      and ultrastructural changes. Pratical and theoretical values.

PMID- 4373093
TI  - Antiviral effect of asparaginase and of Burkitt cell extracts in combination with
      other drugs.

PMID- 4373094
TI  - Fractionation of cigarette smoke condensate prior to bioassays for
      carcinogenicity.

PMID- 4373095
TI  - [Plasmatic 17-alpha-hydroxyprogesterone in congenital adrenal hyperplasia due to
      21 hydroxylase deficiency, treated and untreated].

PMID- 4373096
TI  - Developmental patterns of glycerokinase and cytochrome-c-oxidase in the brown
      adipose tissue of hypotrophic rats.

PMID- 4373097
TI  - The effects of ACTH, dexamethasone and HCG on plasma levels of
      dihydrotestosterone in hirsutism.

PMID- 4373098
TI  - Cytoplasmic tubule-containing vacuoles and endoplasmic tubuloreticular inclusions
      in the lymphocytes of a child with an unidentified form of cerebroretinal
      degeneration.

PMID- 4373099
TI  - Effect of polyelectrolytes on the kinetics of ionic reactions. III. Hydrolysis of
      pyrophosphate in poly-(ethyleneimine) solutions.

PMID- 4373100
TI  - Reagent gases for G.C.-M.S. analyses.

PMID- 4373101
TI  - Studies on isolation and characterization of ceramide trihexosidase.

PMID- 4373102
TI  - [Effect of hydrocortisone on blood sugar and glycogenesis in tumor-bearing rats].

PMID- 4373103
TI  - [Mitotic cycles of hepatoma 22A cells].

PMID- 4373104
TI  - Toxicity study of two oil spill reagents toward Hudson River fish species.

PMID- 4373105
TI  - Influence of storage temperature of florisil on analysis of polychlorinated
      biphenyls.

PMID- 4373106
TI  - Biochemical changes induced by ethyl acetate in blood and liver of rat.

PMID- 4373107
TI  - Possible role of dark cells of the collecting tubules in acidification of the
      urine.

PMID- 4373108
TI  - Letter: Camera or scanner for bone scans using 99Tcm pyrophosphate.

PMID- 4373109
TI  - Multiple intraosseous lipomas with type-IV hyperlipoproteinemia. A case report.

PMID- 4373110
TI  - Half-clearance time of 198Au colloid as a discriminant of liver abscess and
      malignancy.

PMID- 4373111
TI  - Odontoma formation in the jaw following irradiation of an adolescent.

PMID- 4373112
TI  - Angiographic evaluation of the regression of an extensive juvenile nasopharyngeal
      angiofibroma after radiation therapy: a case report with therapeutic
      implications.

PMID- 4373113
TI  - Fibrous histiocytoma of the thumb.

PMID- 4373114
TI  - Editorial: Late onset of puberty.

PMID- 4373115
TI  - Letter: Comparison between free thyroxine index and effective thyroxine ratio.

PMID- 4373116
TI  - Plasma tryptophan and sheep.
AB  - Free, bound, and total plasma tryptophan (F.P.T., B.P.T., and T.P.T.) levels have
      been measured throughout the night in six young female volunteers. All-night
      polygraphic sleep recordings were also made. No direct temporal relationship was
      found between plasma tryptophan levels and specific sleep stages. The mean F.P.T.
      levels, however, were found to have a positive correlation with rapid-eye
      movement (R.E.M.) sleep and a negative correlation with non-R.E.M. sleep. An
      inverse relationship existed between the F.P.T. and B.P.T. levels. There appeared
      to be a diurnal variation in F.P.T. levels, with high readings in the first half
      of the night.

PMID- 4373117
TI  - Peripheral neuropathy in acromegaly.

PMID- 4373118
TI  - Pathophysiology in multiple sclerosis.

PMID- 4373119
TI  - Clinical features of spinal vascular malformations.

PMID- 4373120
TI  - The pattern of peripheral nerve regeneration induced by crush in rats with severe
      acrylamide neuropathy.

PMID- 4373121
TI  - Tangier disease.

PMID- 4373122
TI  - Peripheral nerve changes in amyloid neuropathy.

PMID- 4373123
TI  - Endoneurial space and its constituents in the sural nerve of patients with
      neuropathy.

PMID- 4373124
TI  - Morphine and related compounds: evidence that they decrease available
      neurotransmitter in Aplysia californica.

PMID- 4373125
TI  - [Spontaneous activity of Purkinje cells in free moving cat: a statistical study
      of complex spikes (author's transl)].

PMID- 4373126
TI  - [Effect of pinealectomy on sleep stages and rhythms of the male rat].

PMID- 4373128
TI  - Synaptic connections between medullary inspiratory neurons and phrenic
      motoneurons as revealed by cross-correlation.

PMID- 4373127
TI  - Effects of electrical stimulation on acetylcholine levels in central cholinergic
      nerve terminals.

PMID- 4373129
TI  - Mesencephalic dopamine neurons projecting to neocortex.

PMID- 4373130
TI  - Histochemical confirmation for dopaminergic innervation of the rat cerebral
      cortex after destruction of the noradrenergic ascending pathways.

PMID- 4373131
TI  - (3H)Uridine uptake and incorporation into RNA in the C-6 glial cells following
      dibutyryl cyclic AMP treatment.

PMID- 4373132
TI  - Choline uptake in glial cell cultures.

PMID- 4373133
TI  - L-Tryptophan as a selective histochemical marker for serotonergic neurons in
      single-cell recording studies.

PMID- 4373135
TI  - Simultaneous recording of pre- and postsynaptic potentials during the
      degeneration of the optic tract fiber input to the lateral geniculate nucleus of
      cats.

PMID- 4373134
TI  - Denervation in the primary olfactory pathway of mice: biochemical and
      morphological effects.

PMID- 4373136
TI  - Reversible suppression of the geniculate PGO waves and of the concomitant
      increase of excitability of the intrageniculate optic nerve terminals in cats.

PMID- 4373137
TI  - Hypophysectomy, ACTH1-10 and in vitro protein synthesis in rat brain stem slices.

PMID- 4373139
TI  - Postmortem isolation of synaptosomes from human brain.

PMID- 4373138
TI  - 6-Hydroxydopamine lesions of olfactory tubercles and caudate nuclei: effect on
      amphetamine-induced stereotyped behavior in rats.

PMID- 4373140
TI  - Tectal influences on cat ocular motoneurons.

PMID- 4373141
TI  - Effects of trans-membrane polarization and TEA injection on monosynaptic actions
      from motor cortex, red nucleus and group Ia afferents on lumbar motoneurons in
      the monkey.

PMID- 4373142
TI  - Characteristics of the rat C-6 glioma maintained in organ culture systems.
      Production of glial fibrillary acidic protein in the absence of
      gliofibrillogenesis.

PMID- 4373143
TI  - [Therapeutic progress in the area of arterial hypertension].

PMID- 4373144
TI  - [Congenital ring-constrictions of the extremities].

PMID- 4373145
TI  - [Hyperlipemias].

PMID- 4373147
TI  - Thermal inactivation of avian liver and muscle fructose 1,6-diphosphatases in the
      presence of fructose 1,6-diphosphate, AMP, and divalent cations.

PMID- 4373146
TI  - Incorporation of sialic acid into sialidase-treated apolipoprotein of human, very
      low density lipoprotein by a pork liver sialytransferase.

PMID- 4373148
TI  - Role of tocopherol in the reduction of mitochondrial NAD.

PMID- 4373149
TI  - Some characteristics of the exchange of lecithin between rabbit erythrocytes and
      serum.

PMID- 4373150
TI  - Enterovirus neutralizing activity in the gastrointestinal tract of piglets.
AB  - Neutralizing activity against porcine enterovirus strain T80 was demonstrated in
      the contents of the stomach, duodenum or ileum of four piglets which were
      suckling dams whose milk contained neutralizing substances against the same
      virus. No neutralizing activity was detected in the gastrointestinal contents of
      an unsuckled piglet or in four weaned piglets. Extracts of intestinal tissue from
      each of the above piglets failed to neutralize the virus. Four weaned piglets
      were dosed orally with live T80 virus. From nine days after infection virus
      neutralizing activity was found in extracts of tissue prepared from the duodenum,
      jejunum, ileum, caecum and colon but not in the contents of the gastrointestinal
      tract and a serological response to the virus was demonstrated. No virus
      neutralizing activity was detected in gastrointestinal tissue or contents from
      four weaned piglets inoculated parenterally with live T80 virus or in four
      piglets dosed orally with inactivated T80 virus and these piglets did not respond
      serologically to the virus.

PMID- 4373151
TI  - Minimal inhibitory concentrations of twenty antimicrobial agents to animal
      pathogens.
AB  - Minimal inhibitory concentration (M.I.C.) values as determined by an agar-plate
      dilution method for 60 bacterial isolates, consisting of Salmonella typhimurium,
      Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus of animal
      origin against 20 antimicrobial drugs are presented. Of all the drugs, gentamicin
      had the best in vitro antibacterial activity in terms of M.I.C. when considering
      all the species of organisms together, while spectinomycin had the least
      activity.An inoculum replicator was a convenient tool in carrying out the agar
      plate-dilution method.A comparison of the M.I.C. values of 42 isolates of S.
      typhimurium with the results obtained by low level method and the Bauer-Kir-by
      method showed that with few exceptions, there is a general agreement.

PMID- 4373152
TI  - Necrotic enteritis in broiler chickens. II. Pathology and proposed pathogenesis.
AB  - The intestines from 124 dead, sick and normal broiler chickens from 24 cases of
      necrotic enteritis were subjected to histological examination. Tissue sections
      from the duodenum, jejunum, ileum and ceca from each broiler were examined
      histologically for lesions of necrotic enteritis and the presence of coccidia.
      Lesions of necrotic enteritis were present in one or more areas of the intestine
      in all but six of 94 dead or sick birds and they were most common and severe in
      the jejunum. Coccidia were found in only small numbers in both diseased and
      normal birds. Brown and Brenn stained sections showed Gram-positive bacilli
      intimately associated with early necrotic lesions on the tips of villi. Tissue
      sections from the intestines of sick birds permitted a proposed pathogenesis for
      this disease with the lesion starting at the tips of villi. The similarity in
      pathogenesis and pathological lesions in this disease of broilers and Clostridium
      perfringens type C enteritis in baby pigs is discussed.

PMID- 4373153
TI  - Sporulation and enterotoxin production by Clostridium perfringens type A under
      conditions of controlled pH and temperature.

PMID- 4373154
TI  - Demonstration in Aspergillus niger of adenyl cyclase, a cyclic adenosine 3',5'
      monophosphate-binding protein, and studies on intracellular and extracellular
      phosphodiesterases.

PMID- 4373155
TI  - CO2 fixation by the facultative autotroph Thiobacillus novellus during autotrophy
      heterotrophy interconversions.

PMID- 4373157
TI  - Chronic benign congenital myopathy: fingerprint body type.

PMID- 4373156
TI  - Regulation of chloramphenicol synthesis in Streptomyces sp. 3022a. Properties of
      arylamine synthetase, an enzyme involved in antibiotic biosynthesis.

PMID- 4373158
TI  - A review of acrylamide neurotoxicity. Part I. Properties, uses and human
      exposure.

PMID- 4373159
TI  - Letter: Klippel-Trenaunay-Weber syndrome.

PMID- 4373160
TI  - [Swine diseases of viral etiology in the province of Quebec. III.
      Encephalomyelitis and para-influenza virus infection].

PMID- 4373161
TI  - A field trial to evaluate an intranasal infectious bovine rhinotracheitis
      vaccine.

PMID- 4373162
TI  - Metabolic studies of 5-fluorouracil. II. Influence of the route of administration
      on the dynamics of distribution in man.

PMID- 4373163
TI  - The prognostic significance of DHS skin tests in patients with carcinoma of
      bronchus.

PMID- 4373164
TI  - Radiation carcinogenesis: an unusual familial occurrence of neoplasia following
      irradiation in childhood for benign disease.

PMID- 4373165
TI  - Reticulum cell sarcoma of the colon following renal transplantation.

PMID- 4373166
TI  - The management of Wilms' tumor: a comparison of two regimens.

PMID- 4373167
TI  - [Radical neck dissection in advanced tumors of the head and neck. Considerations
      on 52 cases].

PMID- 4373168
TI  - Effect of blockade of angiotensin-I converting enzyme on the blood pressure of
      renal hypertensive rabbits.

PMID- 4373169
TI  - [Levels of ACTH, renin and angiotensin II in the plasma of patients with burns].

PMID- 4373170
TI  - Bacterial plasmids.

PMID- 4373171
TI  - Sequences containing methylated nucleotides at the 5' termini of messenger RNAs:
      possible implications for processing.

PMID- 4373172
TI  - Increased collagen synthesis in Kirsten sarcoma virus-transformed BALB 3T3 cells
      grown in the presence of dibutyryl cyclic AMP.

PMID- 4373173
TI  - A new mechanism for steroid unresponsiveness: loss of nuclear binding activity of
      a steroid hormone receptor.

PMID- 4373174
TI  - Accumulation of water during transformation of cells by an avian sarcoma virus.

PMID- 4373175
TI  - [Contribution to the etiology and epidemiology of acute virus and mycoplasmatic
      infection. I. Laboratory findings].

PMID- 4373176
TI  - [Aerotolerant mutant of C. perfringens A (author's transl)].

PMID- 4373178
TI  - [Determination and separation of various psychopharmaceutical agents using thin
      layer chromatography with Silufol UV].

PMID- 4373177
TI  - [Phospholipases of bacterial origin (author's transl)].

PMID- 4373179
TI  - [Proposals for the preparation and testing of radiopharmac critical agents.
      Proposal for the preparation and testing of 99m Tc-Sn pyrophosphate for bone
      scintigraphy].

PMID- 4373180
TI  - [N-oxidation of isomeric fomocaines and the bioreduction of their N-oxides].

PMID- 4373181
TI  - [Presomen Special administered to women after surgical removal of ovaries
      (author's transl)].

PMID- 4373182
TI  - Enhancement by alkylating agents of chemical carcinogen transformation of hamster
      cells in culture.

PMID- 4373183
TI  - A phosphorylation of steroids and a dienone-phenol rearrangement leading to a
      secosteroidal aldehyde which has a strong toxicity.

PMID- 4373184
TI  - Clinical application of cytochrome A assay of liver specimens for operative
      indication in critically ill patients with liver failure.

PMID- 4373186
TI  - [Cytosoluble receptor of androgens in a striated skeletal muscle].

PMID- 4373185
TI  - [Existence of projections of posterior nerves from the lateral line on the
      Mauthner cell; their antagonistic effect on the activation of this neuron by
      vestibular afferences].

PMID- 4373187
TI  - [Effect of cyclic AMP and 5'AMP on meiosis and early development of Eisenia
      foetida ova].

PMID- 4373188
TI  - [Several receptors per cell for the same and for different steroid hormones.
      Possible pharmacologic consequences].

PMID- 4373189
TI  - [Urinary steroids in the thyroidectomiced rat (author's transl)].

PMID- 4373190
TI  - Fasting serum lipoproteins in rural Africans in Rhodesia, measured by membrane
      filtration and nephelometry.

PMID- 4373192
TI  - Phospholipid interference and other variables in analysis of non-esterified fatty
      acids by copper soap formation.

PMID- 4373191
TI  - Serum lipid and lipoprotein levels in normal Chinese.

PMID- 4373193
TI  - Young adult osteoporosis.

PMID- 4373194
TI  - Studies on pathogenesis and treatment in postmenopausal and senile osteoporosis.

PMID- 4373195
TI  - Hypocalcaemia and hypoparathyroidism.

PMID- 4373196
TI  - The physiology of parathyroid hormone.

PMID- 4373197
TI  - Hurler/Scheie genetic compound (mucopolysaccharidosis IH/IS) in Japanese
      brothers.

PMID- 4373199
TI  - Subcutaneous mastectomy.

PMID- 4373198
TI  - An extrarenal Wilms' tumor arising from a sacrococcygeal teratoma.

PMID- 4373200
TI  - Proceedings. Urinary cyclic AMP excretion in thyroid disease.

PMID- 4373201
TI  - Proceedings: Alterations in liver adenylate cyclase responsiveness during
      induction of tumours in rat liver with 3'-methyl-4-dimethylaminoazobenzene.

PMID- 4373202
TI  - The inhibition of renin secretion by alpha-adrenergic stimulation in the isolated
      rat kidney.

PMID- 4373203
TI  - The effects of exogenous parathyroid hormone on plasma and urinary adenosine 3',
      5'-cyclic monophosphate in man.

PMID- 4373205
TI  - Hormonal induction of threonine dehydratase in postnatal rat liver.

PMID- 4373204
TI  - Effects of vertebrate adipokinetic hormones on the rate of in vitro lipid release
      in insects.

PMID- 4373206
TI  - Lack of vitamin D3 synthesis by goldfish (Carassius auratus L.).

PMID- 4373207
TI  - Circulating lipids in the golden hamster (Mesocricetus auratus).

PMID- 4373208
TI  - Disc electrophoresis of plasma proteins of fish. Physical and chemical
      characters; localization of fibrinogen, transferrin and ceruloplasmin in the
      plasma of the rainbow trout (Salmo gairdnerii Richardson).

PMID- 4373209
TI  - Liver carabamyl phosphate synthetase in the primitive freshwater bony fishes
      (Chondrostei, Holostei).

PMID- 4373210
TI  - Effect of dibutyryl-cyclic AMP on collagen and non-collagen protein synthesis in
      cultured human cells.

PMID- 4373211
TI  - Autoradiographic assessment of proteolytic enzyme action using skeletal
      connective tissue matrices.

PMID- 4373212
TI  - Biochemical and morphological studies on collagens of horny sponges. Ircinia
      filaments compared to spongines.

PMID- 4373213
TI  - The collagenase of carrageenin granuloma.

PMID- 4373214
TI  - Induction of liver growth by xenobiotic compounds and other stimuli.

PMID- 4373215
TI  - Experimental aspects of growth plate disorders. A study concerning chondrocytic
      lysosomes in different physical and metabolic conditions.

PMID- 4373216
TI  - [Influenza and parainfluenza virus infections among Peking children. Their
      etiology and clinical features].

PMID- 4373217
TI  - [Primary malignant liver tumors in infants and children: report of 12 cases].

PMID- 4373218
TI  - Infectious mononucleosis.

PMID- 4373219
TI  - [Electric current generation by cytochrome oxidase, H+-ATPase and
      bacteriorhodopsin].

PMID- 4373220
TI  - [Synthesis of inorganic pyrophosphate at the respiratory chain level in
      submitochondrial particles of bovine heart mitochondria].

PMID- 4373221
TI  - [Poliomyelitis in the Federal Republic of Germany. A retrospective study of 1973
      (author's transl)].

PMID- 4373223
TI  - [Metabolic and hormonal peculiarities of obesity].

PMID- 4373222
TI  - [Letter: Hypocalcemia in renal insufficiency].

PMID- 4373224
TI  - [Indirect double discharge].

PMID- 4373225
TI  - Dynamics of insulin release and microtubular-microfilamentous system. VI. Effect
      of D2O.

PMID- 4373226
TI  - Location of feedback receptors: effects of intracranially implanted steroids on
      plasma LH and LRF response.

PMID- 4373227
TI  - Synandrogenic and antiandrogenic effect of progestins: comparison with
      nonprogestational antiandrogens.

PMID- 4373229
TI  - Actin in pancreatic islet cells.

PMID- 4373228
TI  - Estrogenic regulation of cytoplasmic receptor populations in estrogen-responsive
      tissues of the rat.

PMID- 4373230
TI  - Possible role of cyclic AMP and prostaglandin E1 in the dopaminergic control of
      prolactin release.

PMID- 4373231
TI  - Uterine responsiveness to estrogen in 4-day cycling and in estrogen-primed
      ovariectomized rats as assessed by uptake and incorporation of (3H) leucine.

PMID- 4373232
TI  - Glucocorticoid-binding macromolecules in the lactating mammary gland of the vole.

PMID- 4373233
TI  - Pituitary-adrenal function in lactating rats.

PMID- 4373234
TI  - Effects of a single and prolonged ACTH treatment on adrenal, ovarian, uterine and
      renal blood flow in mice and golden hamsters.

PMID- 4373235
TI  - [Active "negative" distribution as a constituent of endocrine regulation. Studies
      on corticotrophic partial function].

PMID- 4373237
TI  - Phenylalanyl-tRNA synthetase from yeast. Steady-state kinetic investigation of
      the reaction mechanism.

PMID- 4373236
TI  - Regulatory mechanism of muscle contraction with special reference to the Ca
      troponin-tropomyosin system.

PMID- 4373238
TI  - Accessible DNA in chromatin.

PMID- 4373239
TI  - Role of manganous ion in the kinetics of pig-heart NAD-specific isocitrate
      dehydrogenase.

PMID- 4373240
TI  - Yeast inorganic pyrophosphatase: studies on metal binding.

PMID- 4373241
TI  - Conformational changes in myosin under ATP hydrolysis.

PMID- 4373242
TI  - Proteinase K from Tritirachium album Limber.

PMID- 4373243
TI  - Phosphorylation of vinblastine-isolated microtubules from chick-embryonic
      muscles.

PMID- 4373244
TI  - Enzymes involved in ketone utilization in different types of muscle: adaptation
      to exercise.

PMID- 4373245
TI  - The role of acetyl-CoA in the reaction pathway of pig-liver pyruvate carboxylase.

PMID- 4373246
TI  - Influence of iron deficiency on the cytochromes of Rhodopseudomonas spheroides.

PMID- 4373247
TI  - Early biochemical changes in phytohemagglutinin-stimulated peripheral blood
      lymphocytes from normal and tumor-bearing rats.

PMID- 4373248
TI  - A sex-dependent difference in the type of tumours induced by dimethylnitrosamine
      in the livers of C3Hf mice.

PMID- 4373249
TI  - Ouabain-induced potentiation on the contractions of the guinea-pig vas deferens.

PMID- 4373250
TI  - The effect of pH on tachyphylaxis to angiotensin peptides in the isolated guinea
      pig ileum and rat uterus.

PMID- 4373251
TI  - The effect of metronidazole on striated muscle.

PMID- 4373252
TI  - The role of muscarinic receptors in synaptic transmission and its modulation in
      the rabbit superior cervical ganglion.

PMID- 4373253
TI  - The effect of prednisolone on the rat phrenic nerve-diaphragm preparation treated
      with hemicholinium.

PMID- 4373254
TI  - Inhibition of oxytocic and hypotensive activities of bradykinin by bradykinin
      binding antibodies.

PMID- 4373255
TI  - Virally transformed cells and cytochalasin B. I. The effect of cytochalasin B on
      cytokinesis, karyokinesis and DNA synthesis in cells.

PMID- 4373256
TI  - Long-term cell culture of adult rat liver epithelial cells.

PMID- 4373257
TI  - The effects of cell population density on the plasma membrane of Acanthamoeba
      castellanii.

PMID- 4373258
TI  - Action of organophosphorus compounds on the p-nitrophenyl phosphatase of
      membranes from rabbit and guinea pig polymorphonuclear leucocytes.

PMID- 4373260
TI  - Action of organophosphorus compounds on the cation-sensitive p-nitrophenyl
      phosphatase of membranes from the retinal nerve of the squid.

PMID- 4373259
TI  - Isolation and characterization of norleucine-resistant baby hamster kidney cells.

PMID- 4373261
TI  - Inhibition by x-irradiation and antimetabolites of DNA synthesis without
      affecting cAMP elevation in isoproterenol-stimulated mouse parotid gland.

PMID- 4373262
TI  - Studies on the mechanism of actinomycin D resistance of an SV40-transformed
      hamster cell line.

PMID- 4373263
TI  - Synthesis of surface glycoproteins and glycosphingolipids in db-cAMP-treated
      normal and virus-transformed 3T3 cells.

PMID- 4373264
TI  - Electronic coupling between motoneurones in the abducens nucleus of the cat.

PMID- 4373265
TI  - A long propriospinal system with direct effect on motoneurones and on
      interneurones in the cat lumbosacral cord.

PMID- 4373266
TI  - Inhibitory organization of the thalamic ventrobasal neurons with different
      peripheral representations.

PMID- 4373268
TI  - Manganese inhibits adenylate cyclase activity and stimulates phosphodiesterase
      activity in neuroblastoma cells: its possible implication in manganese-poisoning.

PMID- 4373267
TI  - Characteristics of the thalamic ventrobasal relay neurons as a function of
      conduction velocities of medial lemniscal fibers.

PMID- 4373269
TI  - Early histochemical changes induced by manganese chloride in the renal tissue of
      rabbit.

PMID- 4373271
TI  - Effect of low calcium concentration on the oxidation of NAD-linked substrates in
      rat liver and tumor mitochondria.

PMID- 4373270
TI  - Cell membrane permeability change: an important step in hormone action.

PMID- 4373272
TI  - Inhibition of Neisseria catarrhalis NE-11 transformation.

PMID- 4373273
TI  - Restorative effect of cyclic AMP on the bioelectric processes of calcium deprived
      ganglia.

PMID- 4373274
TI  - Oncornavirus released from long-term cultures of human leukemic cells.

PMID- 4373275
TI  - Inhibition of spontaneous and induced ovulation in rats by non-steroidal agents.

PMID- 4373276
TI  - The effect of neuraminidase on the 5-hydroxytryptamine uptake of human platelets.

PMID- 4373278
TI  - The effect of theophylline on oxytocin induced contractions in the chronically
      catheterized pregnant rabbit.

PMID- 4373277
TI  - On the modification of the divalent cation-binding by phospholipids in tumours.

PMID- 4373279
TI  - Ultrastructure of the neurohypophysial glial cells following stalk transection in
      the rat.

PMID- 4373280
TI  - In vitro and in vivo inhibitory action of 2-amino-4,6-dichloropyrimidine on polio
      and herpes virus.

PMID- 4373281
TI  - How well does man thermoregulate during sleep?

PMID- 4373282
TI  - Peripheral neuropathy associated with inhalation of methyl-n-butyl ketone.

PMID- 4373283
TI  - Kininogenase in kidney after ligation of the ureter and after experimental aortic
      stenosis.

PMID- 4373284
TI  - [Effect of electric stimulation on phosphorylase activity and cAMP content in
      insect flight muscles of Locusta migratoria].

PMID- 4373285
TI  - Rifampicin and cysteamine protect against the mushroom toxin phalloidin.

PMID- 4373286
TI  - Unusual cases of facial paralysis.

PMID- 4373287
TI  - [Recent advances in the field of clinical chronopharmacology].

PMID- 4373289
TI  - Dissociation of rabbit muscle cyclic AMP-dependent protein kinase into catalytic
      and regulatory subunits by p-chloromercuribenzoate and methylmercuric chloride.

PMID- 4373288
TI  - Liver phosphorylase phosphatase: regulation of activity by ATP and Mg ions.

PMID- 4373290
TI  - Eukaryotic cytochrome c-like properties of cytochrome c-550 (Thiobacillus
      novellus).

PMID- 4373291
TI  - Activities of ribosomal cores deprived of proteins L7, L10, L11 and L12.

PMID- 4373292
TI  - Absence of binding of thyroid-stimulating hormone subunits to specific sites of
      thyroid cells.

PMID- 4373293
TI  - The use of a new series of cleavable protein-crosslinkers on the Escherichia coli
      ribosome.

PMID- 4373294
TI  - Alkaline phosphatase of Dictyostelium discoideum: cell surface location and
      colchicine effect on internalization during phagocytosis.

PMID- 4373295
TI  - Requirement for specific carbon sources in the low temperature induction of
      glycerol kinase in Neurospora crassa.

PMID- 4373296
TI  - Experiments on the effectiveness of inactivatedd infectious bovine
      rhinotracheitis vaccine.

PMID- 4373297
TI  - Immunization of cattle with apolyvalent bovine adenovirus vaccine.

PMID- 4373298
TI  - Immunization of cattle with an attenuated IBR vaccine.

PMID- 4373299
TI  - Vaccination of calves against infectious bovine rhinotracheitis using a
      temperature senstive mutant.

PMID- 4373300
TI  - Renin, angiotensin, and norepinephrine in alloxan diabetes.

PMID- 4373301
TI  - [Evidence for circadian variability in the renin-angiotensin II system (author's
      transl)].

PMID- 4373302
TI  - Estimation of specific antibody to type 2 Herpes simplex virus among patients
      with carcinoma of the uterine cervix.

PMID- 4373303
TI  - Combined effect of nitrogen mustard and DNA repair inhibitor on the resistant
      tumor.

PMID- 4373304
TI  - [Clinical aspects of amebic dysentery].

PMID- 4373305
TI  - [The lutein cell tumour of the ovary--a specific tumour of pregnancy (author's
      transl)].

PMID- 4373306
TI  - Cytogenetic and complementation analyses of recessive lethal mutations induced in
      the X chromosome of Drosophila by three alkylating agents.

PMID- 4373307
TI  - The role of latent viruses in subline differentiation in inbred strains of mice.

PMID- 4373308
TI  - [Studies on the problem of growth of seperated microorganisms on glass-fiber fine
      dust and glass-fiber high-capacity-floating-particle filters].

PMID- 4373309
TI  - [Some problems of the circulation of enteroviruses in environmental objects].

PMID- 4373310
TI  - [Hygienic standardization of the average daily maximum permissible concentrations
      of propyl and isopropyl alcohols in the atmosphere].

PMID- 4373311
TI  - [Complex evaluation of the physical development of children and adolescents].

PMID- 4373312
TI  - [Molecular mechanisms of the primary pathological action of silica on the
      macrophages and ways to research methods for the pathogenetic prophylaxis of
      silicosis].

PMID- 4373313
TI  - [Feminizing testicular tumor of the trophoblastoma type].

PMID- 4373314
TI  - Plasma androstenedione (A) and dihydrotesto-terone (DHT) in patients with
      trophoblastic disease and the effect of chemotherapy and oophorectomy.

PMID- 4373315
TI  - [Clostridium perfringens sepsis].

PMID- 4373316
TI  - [Experimental evaluation of the infection-promoting properties of mucin,
      cortisone, cyclophosphamide and antilymphocyte serum].

PMID- 4373317
TI  - [Developmental abnormalities of the inferior vena cava and pelvic veins. An
      investigation of the haemodynamics of the venous low-pressure system (author's
      transl)].

PMID- 4373318
TI  - [Radiological and angiographic signs of so-called "spontaneous Blalock operation"
      in truncus arteriosis communis (author's transl)].

PMID- 4373319
TI  - [The angiographic differential diagnosis of right-sided diaphragmatic defects
      with liver prolapse (author's transl)].

PMID- 4373320
TI  - [Comparative angiographic investigations of the upper limb under local, regional
      and general anesthesia (author's transl)].

PMID- 4373321
TI  - [Sipple syndrome (author's transl)].

PMID- 4373322
TI  - Renal angiomyolipoma versus renal carcinoma. Is an angiographic differential
      diagnosis possible?

PMID- 4373324
TI  - [The demonstration of parenchymal calcification on angiograms of abdominal organs
      (evaluation of film quality of rapid serial exposures) (author's transl)].

PMID- 4373323
TI  - [Blood pressure and roentgenological size of the kidney in chronic
      glomerulonephritis (author's transl)].

PMID- 4373325
TI  - [A circumscribed, small cyst mastopathy simulating a malignant tumour (author's
      transl)].

PMID- 4373326
TI  - [The radiological features of mammary duct abnormalities on galactography; a
      comparison with cytological and histological findings (author's transl)].

PMID- 4373327
TI  - [Mammary arteriography (author's transl)].

PMID- 4373328
TI  - [Scintigraphy of female breast with 99mTcO4 (author's transl)].

PMID- 4373329
TI  - [A comparison of radiological and scintigraphic findings in ankylosing
      spondylitis (morbus Bechterew) (author's transl)].

PMID- 4373330
TI  - [Improved functional scintigraphy after injection into the femoral vein (author's
      transl)].

PMID- 4373332
TI  - [Urethral ectopy of a simple ureter].

PMID- 4373331
TI  - [AURA: automatic documentation from original texts (author's transl)].

PMID- 4373336
TI  - [Ultra-sound diagnosis in children (author's transl)].

PMID- 4373333
TI  - [Clinical picture of polyaneurysmal dystrophy].

PMID- 4373335
TI  - [A case of "coalitio vertebrae" in the cervical spine].

PMID- 4373334
TI  - [Hemangioendothelioma of the liver following thorotrast administration 30 years
      ago].

PMID- 4373337
TI  - [Spontaneous pneumo-oesophagogram (author's transl)].

PMID- 4373338
TI  - [Cardiac failure due to hypertrophy of the adenoids (author's transl)].

PMID- 4373339
TI  - [Functional examinations during defaecation in childhood (author's transl)].

PMID- 4373340
TI  - [Idiopathic juvenile osteoporosis (author's transl)].

PMID- 4373341
TI  - [The syndrome of the upper calyx in children with chronic pyelonephritis
      (author's transl)].

PMID- 4373342
TI  - [A rare variant of retrocaval ureter (author's transl)].

PMID- 4373343
TI  - [Retro-peristalsis of the ureter (author's transl)].

PMID- 4373344
TI  - [The effect of iodinated contrast media on pathogens in the urinary tract
      (author's transl)].

PMID- 4373345
TI  - [Post mortem magnification angiography of the kidneys, using fat soluble contrast
      media (author's transl)].

PMID- 4373346
TI  - [Blood-flow measurements with 133Xe after clinical renal transplants (author's
      transl)].

PMID- 4373347
TI  - [The information content of the isotope nephrogram for the demonstration of
      compensatory hyperplasia of the contra-lateral kidney after unilateral renal
      artery ligation in animals (author's transl)].

PMID- 4373348
TI  - [The value of gamma cavography and its indications (author's transl)].

PMID- 4373349
TI  - [The interpretation of the 99mTcO-4-salivary gland scans (author's transl)].

PMID- 4373350
TI  - [Scintigraphic findings and dynamics of storage of 197HgCl2 in exophthalmos
      (author's transl)].

PMID- 4373351
TI  - [X-ray film evaluation with a new equidensitometric film (author's transl)].

PMID- 4373352
TI  - [Bilateral renal angiomyolipomatosis].

PMID- 4373353
TI  - [Benign ureteral tumors].

PMID- 4373354
TI  - [Crossed renal dystopia with retrovasal ureter].

PMID- 4373355
TI  - [Arteriovenous kidney fistula following percutaneous kidney biopsy].

PMID- 4373356
TI  - [Differentiation of cold spots on the thyroid gland using thyroid cystography].

PMID- 4373357
TI  - [Studies on the influence of a fat-modified diet in healthy subjects and in
      patients with hyperlipoproteinemia].

PMID- 4373358
TI  - [Course of acute kidney failure].

PMID- 4373359
TI  - Dream recall and the menstrual cycle.

PMID- 4373360
TI  - [The effect of interferon and guanidine on the inactivation of RNA of foot-and
      mouth disease virus infected cells].

PMID- 4373361
TI  - Single-copy nuclear DNA in the cytoplasm of undifferentiated embryo cells and
      tumor cells of man, chick and hamster.

PMID- 4373362
TI  - Preparation of pure choline and ethanolamine plasmalogens with the use of
      purified lipase from porcine pancreas.

PMID- 4373364
TI  - Aminopeptidase K from Tritirachium album Limber. I. Isolation and some
      properties.

PMID- 4373365
TI  - [Biosynthesis of cytochrome c, III. Incorporation in vivo of radioactive delta
      aminolevulinate, alpha-ketoglutarte, and succinicate into cytochrome c of the
      honey bee (author's transl)].

PMID- 4373363
TI  - Properties and specificities of sphingosine kinase from blood platelets.

PMID- 4373366
TI  - Synthesis of labelled phosphatidyl-N,N-dimethylethanolamine and
      phosphatidylcholine.

PMID- 4373367
TI  - Hormone-mediated dimerization of microsomal estradiol receptor.

PMID- 4373368
TI  - Conformational differences in Myosin, II. Evidence for differences in the
      conformation induced by bound or hydrolyzed adenosine triphosphate.

PMID- 4373369
TI  - Influence of noradrenalin, prostaglandin E1 and inhibitors of phosphodiesterase
      activity on levels of the cyclic adenosine 3':5'-monophosphate in somatic cell
      hybrids.

PMID- 4373370
TI  - Specific estrogen binding sites on the liver chromatin of estrogen-pretreated
      roosters.

PMID- 4373371
TI  - Biosynthesis of sphingomyelin. Transfer of phosphorylcholine from
      phosphatidylcholine to erythro-ceramide in a cell-free system.

PMID- 4373372
TI  - Isolation and characterization of nuclear membranes from calf and rat thymus.

PMID- 4373373
TI  - Composition of mitochondrial lipids from rat adrenal glands.

PMID- 4373375
TI  - On the mechanism of gluconeogenesis and its regulation. VIII. Differentiation of
      regulatory attacks of glucocorticoids, L-lysine and cyclic AMP in renal
      gluconeogenesis.

PMID- 4373374
TI  - The metabolism of sphingosine bases in Tetrahymena pyriformis. Sphingosine kinase
      and sphingosine-1-phosphate lyase.

PMID- 4373376
TI  - Studies on the biosynthesis of cyclitols, XXX. Purification of myo-inositol-1
      phosphate synthase of rat testes to homogeneity by affinity chromatography on NAD
      sepharose.

PMID- 4373377
TI  - A possible role of the glycerol phosphate cycle in cyclic AMP-stimulated
      gluconeogenesis from lactate in perfused rat livers.

PMID- 4373378
TI  - Evidence for a hexosediphosphatase from the cytoplasm of spinach leaves.

PMID- 4373380
TI  - Adenylate cyclase from Trypanosoma gambiense.

PMID- 4373379
TI  - [Biosynthesis of cytochrome c, IV. The activities of 5-aminolevulinate and
      porphobilinogen synthase at different stages of development of the honey bee
      (author's transl)].

PMID- 4373382
TI  - The relation between the blood-level of a substrate and enzyme kinetics studied
      with glycerol in the rat.

PMID- 4373381
TI  - Purification and properties of a soluble cyclic AMP-dependent protein kinase from
      human platelets.

PMID- 4373383
TI  - Inhibition of the tetrahydrofolic acid cycle in HeLa and LDR cells by
      parainfluenza virus 1 (Sendai).

PMID- 4373384
TI  - The polymorphisms of red cell acid phosphatase, phosphoglucomutase, adenosine
      deaminase, and adenylate kinase in twins.

PMID- 4373386
TI  - Studies on enzymes of renal gluconeogenesis in alcohol-fed rats.

PMID- 4373385
TI  - Genetic markers and anthropometry in the populations of the Egyptian oases of El
      Kharga and El-Dakhla.

PMID- 4373387
TI  - An ultrastructural study of adenoid cystic carcinoma of the human salivary gland.

PMID- 4373388
TI  - The effect of bacterial adjuvants on allograft survival after anti-lymphocyte
      serum (ALS) and donor bone marrow in mice.

PMID- 4373389
TI  - Antibody response in rabbits after smallpox vaccination with varying tissue
      injury.

PMID- 4373391
TI  - Experimental renal hypertension in rhesus monkeys: effect of surgical removal of
      ischaemic kidney on various parameters.

PMID- 4373390
TI  - Changes in the level of hydrolytic enzymes in the caecum and intestine of rats
      infected with a virulent strain of Entamoeba histolytica intracaecally.

PMID- 4373392
TI  - Hyper beta lipoproteinemia (familial hypercholesterolemia). A case report.

PMID- 4373393
TI  - Antiviral activity of an ether-extracted nonviable preparation of Brucella
      abortus.
AB  - Extraction of living Brucella abortus (strain 456) with aqueous ether yielded a
      nonviable, insoluble residue (Bru-Pel). When injected into mice, Bru-Pel was an
      effective, nontoxic interferon stimulus. Mice pretreated with Bru-Pel were
      protected against challenge with otherwise lethal doses of Semliki Forest virus.
      Significant protection was afforded when Bru-Pel was given as many as 7 days
      before virus challenge. Evidence is presented dealing with the complex nature of
      Bru-Pel and with the possibility that the antiviral activity of Bru-Pel may be
      associated not only with the production of interferon, but with a general
      increase in the level of nonspecific resistance in animals.

PMID- 4373394
TI  - Resistance of female mice to vaginal infection induced by Herpesvirus hominis
      type 2: effects of immunization with Mycobacterium bovis, intravenous injection
      of specific Herpesvirus hominis type 2 antiserum, and a combination of these
      procedures.
AB  - The susceptibility of 4- to 6-week-old female white Swiss mice to intravaginal
      inoculation with Herpesvirus hominis type 2 (HVH2) and the effect of prior
      intravenous immunization with Mycobacterium bovis (BCG) and/or treatment with
      specific HVH2 antiserum (SAS) were investigated. Mice inoculated intravaginally
      developed vaginitis, posterior paralysis, encephalitis, and death. Prior
      immunization with BCG either had no effect or appeared in some cases to enhance
      the course of the disease, whereas a single 0.5-ml intravenous injection of SAS
      provided significant protection. However, synergistic interaction of BCG
      immunization and treatment with SAS produced the greatest degree of protection in
      mice challenged intravaginally with HVH2.

PMID- 4373395
TI  - Induction of interferon in mice by mycoplasmas.
AB  - Interferon was induced in mice after intraperitoneal inoculation with four
      different mycoplasmas. Peak levels of between 100 and 300 U of interferon per ml
      were attained by 6 h postinfection with each of the mycoplasmas except Mycoplasma
      arthritidis, which induced higher titers (400 to 11,800 U/ml) by this time. A
      fifth mycoplasma, M. pulmonis, induced interferon inconsistently and at a later
      (72 to 96 h) time. Mycoplasmatales virus MVL51 and sterile mycoplasmal broth did
      not stimulate interferon production in vivo. All of the mycoplasmas and MVL51
      failed to induce interferon in murine spleen cell, peritoneal exudate cell, or
      peripheral blood leukocyte cultures. Preinfecting the mycoplasmas with MVL51 or
      treating the organisms with trypsin or dilutions of specific antisera did not
      enhance their ability to induce interferon in vitro.

PMID- 4373396
TI  - Hyporeactivity due to infection: recognition of a transferable hyporeactive
      factor in the serum of encephalomyocarditis virus-infected mice.
AB  - As previously reported, mice infected with encephalomyocarditis (EMC) virus
      progressively develop a state of hyporeactivity to interferon induction as
      evidenced by an 80% reduction in serum interferon levels produced in response to
      four different inducers administered 96 h after initiation of infection. In the
      current report, this hyporesponsiveness was further documented in vitro in
      peritoneal exudate cells harvested at the time of maximal hyporeactivity (96 h)
      during EMC virus infection. These peritoneal cell preparations (containing no
      detectable interferon or virus) produced significantly less interferon than cells
      from uninfected mice following exposure to Newcastle disease virus or Chikungunya
      virus. More importantly, hyporeactivity could be transferred to normal peritoneal
      cells incubated in serum (containing no detectable interferon or virus) from EMC
      virus-infected mice during the hyporeactive period. Incubation of peritoneal
      exudate cells with up to a 1:200 dilution of serum from hyporeactive animals
      still resulted in a significant reduction in the interferon response induced by
      Newcastle disease virus or Chikungunya virus. Furthermore, it could be shown that
      this serum hyporeactive factor was effective in mouse cells but not in rabbit,
      chicken, or human cells.

PMID- 4373398
TI  - Inability to detect hepatitis B virus or specific antigens in transformed
      chimpanzee lymphocytes.
AB  - Transformed chimpanzee lymphocytes were examined to determine whether they would
      support the replication of hepatitis B virus. After 5 months, no hepatitis B
      virus, hepatitis B surface antigen, or antibody to hepatitis B surface antigen
      was detected.

PMID- 4373397
TI  - Agglutination of trypsinized sheep erythrocytes by the pili of Corynebacterium
      renale.
AB  - Corynebacterium renale strains which possessed numerous pili agglutinated
      trypsinized sheep erythrocytes, whereas those possessing only a few pili did not
      show such activity. By electron microscopy, the pili of C. renale adhered to the
      ghost of trypsinized sheep erythrocytes. After the treatment of C. renale with
      the homologous anti-pili serum, neither the agglutination of trypsinized sheep
      erythrocytes nor the adherence to the ghost by the pili were found. The adhesive
      property of the pili of C. renale was thus demonstrated.

PMID- 4373399
TI  - In vitro tritium labeling of anti-sendai virus antibody.
AB  - Anti-Sendai virus immunoglobulin G was tritium labeled in vitro by the
      borohydride exchange method. Tritium was incorporated into the antibody at 28.5
      muCi per mg of protein, with little detectable loss of antiviral activity.

PMID- 4373400
TI  - The accurate measurement of vanadium in airborne particulates.

PMID- 4373401
TI  - A decade of dreams: a review.

PMID- 4373402
TI  - Enhancement of the radioprotective effects of 2-mercaptoethylamine on colony
      forming cells by agents which alter cyclic nucleotide levels.

PMID- 4373403
TI  - Radiation damage in L-histidine-HCl monohydrate.

PMID- 4373404
TI  - Toxicity to rabbit retina of "epithermal" neutron beam.

PMID- 4373405
TI  - The effect of lithium carbonate on the sleep of depressed patients.

PMID- 4373406
TI  - Androgen receptors in the nonhistone protein fractions of prostatic chromatin.

PMID- 4373407
TI  - Papovaviridae.

PMID- 4373408
TI  - Comparison of the capsid polypeptides of various bluetongue virus serotypes.

PMID- 4373409
TI  - Antiviral antibiotics: inhibition of focus-formation in human or mouse cell
      cultures by sarcoma-inducing oncornaviruses with rifamycins.

PMID- 4373410
TI  - Inhibition of gross murine leukemia virus replication by rifamycin SV and certain
      of its derivatives in vitro.

PMID- 4373411
TI  - Complexity of immunoreactive forms of peptide hormones in plasma and in tissue
      extracts.

PMID- 4373412
TI  - Heterogeneity of circulating insulin and proinsulin in man.

PMID- 4373413
TI  - Plasma proinsulin-like components.

PMID- 4373414
TI  - Common mechanism of action of somatomedin and insulin on fat cells. Further
      evidence.

PMID- 4373415
TI  - Characterization of preparations of radioiodinated human chorionic gonadotropin.

PMID- 4373416
TI  - Neurohypophyseal hormones as precursors of hypophysiotropic hormones.

PMID- 4373417
TI  - Polypeptide hormone-receptor interactions. A new approach to the study of
      pancreatic and gut glucagons.

PMID- 4373418
TI  - [Rupture of the achilles tendon - functional after care].

PMID- 4373419
TI  - Observations on the maturational appearance of the reproductive organs of male
      infants after treatment with ACTH and corticosteroids.

PMID- 4373420
TI  - Evaluation of anti-tumor effect of corticosteroid on human glioma in vitro.

PMID- 4373421
TI  - Histochemical demonstration of changes in liver cell enzymes in pregnant mice
      infected with Coxsackie B3 virus.

PMID- 4373422
TI  - Intense phosphatase activity in the developing rete testis of the newborn rat.

PMID- 4373423
TI  - Vaccination for reproductive efficiency in cattle.

PMID- 4373424
TI  - Causes and control of swine stillbirths.

PMID- 4373425
TI  - Acidolin: an antibiotic produced by Lactobacillus acidophilus.

PMID- 4373426
TI  - A new medium for the detection and enumeration of Clostridium perfringens in
      foods.

PMID- 4373427
TI  - Histamine releasers and hypoxic vasoconstriction in isolated cat lungs.

PMID- 4373428
TI  - Adrenal adaptation to chronic exercise.

PMID- 4373429
TI  - Central neural respiratory stimulatory effect of active respiration.

PMID- 4373430
TI  - Eccrine sweat gland in Macaca mulatta: physiology, histochemistry, and
      distribution.

PMID- 4373431
TI  - Periodic breathing during sleep.

PMID- 4373432
TI  - Primary carcinoma liver (a clinico pathological study of 185 cases with liver
      biopsies).

PMID- 4373433
TI  - Cellular location of degradative enzymes in Staphylococcus aureus.
AB  - Staphylococus aureus, ATCC 6538P, was fractionated into protoplast membranes,
      mesosomal vesicles, periplasm, and cytoplasm. These fractions and the culture
      fluid were then assayed for various degradative enzyme activities. They were not
      restricted to a single fraction nor dispersed homogeneously, but were distributed
      predominantly (on the basis of specific activity) as follows: nuclease in the
      culture fluid; alkaline phosphatase, 5'-nucleotidase, and acid phosphatase in the
      periplasm; adenosine triphosphatase in the protoplast membrane; and protease (low
      levels) in mesosomal vesicles. No significant esterase nor cell wall hydrolytic
      activity was found in any fraction. S. aureus 80/81 was studied for penicillinase
      activity after induction with benzyl penicillin; this enzyme was localized in the
      mesosomal vesicles. Electron microscopy did not reveal any ultrastructural
      changes associated with secretion of the extracellular fraction. Overall, these
      studies demonstrate that degradative enzymes are located in several surface
      compartments and that, therefore, the mesosome does not function as a prototype
      lysosome in S. aureus.

PMID- 4373434
TI  - Regulation of serine transhydroxymethylase activity in Salmonella typhimurium.
AB  - The regulation of serine transhydroxymethylase (EC 2.1.2.1.; l
      serine:tetrahydrofolic-5,10-hydroxymethyltransferase) has been investigated in
      Salmonella typhimurium LT2. Our results indicate that limitation of a methionine
      auxotroph for methionine does not cause derepression of this enzyme as reported
      for Escherichia coli. However, a sixfold decrease in specific activity was
      observed when S. typhimurium cells were grown in glucose minimal medium
      supplemented with serine, glycine, methionine, adenine, guanine, and thymine.
      None of these compounds added to the growth medium individually produced more
      than a 42% reduction of wild-type enzyme activity. This enhanced repression by
      the combination of compounds suggests a form of cumulative repression of this
      enzyme. Growth of serine and thymine auxotrophs, with the respective requirement
      of each limiting, did not result in increased enzyme activity. However, growth of
      a purine auxotroph with a limiting amount of either guanine or inosine resulted
      in a five- to sevenfold increase in enzyme activity. A second condition causing
      significant derepression (fourfold increase) above the levels observed with cells
      grown in minimal medium was the addition of 0.5 mug of trimethoprim per ml, an
      inhibitor of the dihydrofolate reductase activity. (A partial report on this work
      was presented at 1974 meeting of the American Society for Microbiology.)

PMID- 4373435
TI  - Mutants of Salmonella typhimurium defective in transport of branched-chain amino
      acids.
AB  - Five mutants, CD15, CD31, CE4, CE5, and CE14, defective in the transport of
      branched-chain amino acids were isolated as glycyl-l-isoleucine and glycyl-l
      valine requirers from an isoleucine-valine-requiring mutant, KA931, of Salmonella
      typhimurium LT2. Although these transport mutants do not grow in minimal medium
      supplemented with isoleucine (10 mug/ml) and valine (20 mug/ml), where the parent
      strain, KA931, grows normally, they do when the supplements are increased 10-fold
      in concentration, and the growth rate becomes comparable to that of the parent
      strain. When the apparent K(m) and V(max) for uptake of isoleucine, valine, and
      leucine in the transport mutants were compared to those of KA931, the K(m) was
      generally lower in the mutants, and the V(max) for isoleucine and leucine
      decreased to one-fourth to one-seventh and for valine one-eighth to one-fifteenth
      of that in the parent. In all mutants except CE5, the transport of methionine,
      arginine, threonine, and glycine was normal. The transport of threonine in CE5
      appeared to be slightly impaired. In addition to the original mutation in the
      ilvC locus, the transport mutant has a mutation at the ilvT locus, which is
      closely linked to proC and may be located on the side of proC proximal to purE.
      About 26-fold difference in values of the co-transduction is noted in reciprocal
      transductions between KA502 and CD15 strains.

PMID- 4373436
TI  - Properties of two homologous alkaline proteases from Streptomyces rectus.
AB  - Some physicochemical properties of two thermostable proteases from Streptomyces
      rectus are described. The enzymes were judged to be identical with respect to
      molecular weight, inactivation with serine protease inhibitors, and in primary
      structure by peptide analysis. Amino acid analysis indicated the enzymes had
      identical compositions except for their amide content. The molecular weights of
      the enzymes were judged to be 28,000 by sedimentation equilibrium, 26,200 by
      sedimentation diffusion, and 29,100 from amino acid analysis. Titration of the
      proteases with diisopropylfluorophosphate and phenylmethane sulfonylfuoride
      indicate equivalent weights of 28,500 and 32,800 g, respectively, for the
      proteins. The pentapeptide around the serine residue reacting with
      diisopropylfluorophosphate was isolated and had the composition: Asx(1), Gly(1),
      Thr(1), Ser(1), Met(1).

PMID- 4373438
TI  - Characterization of Escherichia coli flagellar mutants that are insensitive to
      catabolite repression.
AB  - In Escherichia coli, the synthesis of the flagellar organelle is sensitive to
      catabolite repression. Synthesis requires the presence of the cyclic adenosine
      monophosphate receptor protein (Crp) and 3',5'-cyclic adenosine monophosphate
      (cAMP); i.e., mutants that lack Crp or adenylcyclase (Cya) synthesize no
      flagella. We isolated and characterized a series of mutants (cfs) that restored
      flagella-forming ability in a Crp strain of E. coli. The mutations in these
      strains were transferred onto episomes and they were then introduced into a
      variety of other strains. The presence of the mutation resulted in flagella
      synthesis in Cya and Crp strains as well as in the wild type grown under
      conditions of catabolite repression. Deletion analysis and other genetic studies
      indicated that: (i) the cfs mutations had a dominant effect when they were in the
      transconfiguration in merodiploids: (ii) they occurred in or very close to the
      flaI gene: and (iii) their expression required the presence of an intact flaI
      gene adjacent to the cfs mutation. Biochemical studies showed that the synthesis
      of at least two flagellar polypeptides, the hook subunit and an amber fragment of
      flagellin, were absent in strains that carried a cya mutation. Their synthesis
      was depressed in strains grown under conditions of catabolite repression. The
      presence of the cfs mutation restored the specific synthesis of these two
      polypeptides. We suggest that the formation of the flaI gene product is the step
      in flagellar synthesis that is catabolite sensitive and requires cAMP. We propose
      a regulatory function for the product of the flaI gene.

PMID- 4373437
TI  - Rhythms of enzyme activity associated with circadian conidiation in Neurospora
      crassa.
AB  - The mycelial growth front of the band strain of Neurospora grown on a solid
      surface exhibits a circadian rhythm of conidiation. Enzyme assays on extracts
      from that mycelium have shown that the activities of 6 of 13 enzymes
      (nicotinamide adenine dinucleotide nucleosidase, isocitrate lyase, citrate
      synthase, glyceraldehydephosphate dehydrogenase, phosphogluconate dehydrogenase,
      and glucose-6-phosphate dehydrogenase) and soluble-protein content oscillate with
      the visible morphological change. The rhythmic enzymes associated with the Krebs
      and glyoxylate cycles are more active during conidiogenesis, whereas the
      activities of the rhythmic enzymes of glycolysis and the hexose monophosphate
      shunt are reduced during that phase. The absence of enzyme oscillations in wild
      type and fluffy strains which do not form conidia under the conditions employed
      suggests that the enzyme fluctuations are associated with conidiogenesis itself.
      Oscillations of enzyme activity as a function of time are restricted to the
      growth front. A permanent record of rhythmicity associated with conidial and
      nonconidial regions does, however, exist in the mycelial mat behind the growth
      front. The activities of three enzymes (nicotinamide adenine dinucleotide
      nucleosidase, glucose-6-phosphate dehydrogenase, and phosphogluconate
      dehydrogenase) are not directly influenced by CO(2) concentration, but are
      correlated with the prescence or absence of conidiation which is controlled by
      CO(2) concentration. In contrast, citrate synthase and malate dehydrogenase
      activities are correlated with changes in CO(2) concentration.

PMID- 4373439
TI  - Salmonella typhimurium mutants defective in cytidine monophosphate kinase (cmk).
AB  - Mutants of Salmonella typhimurium defective in cytidine 5'-monophosphate (CMP)
      kinase (cmk) have been isolated. The mutants also lack the ability to
      phosphorylate 2'-deoxyCMP, indicating that one enzyme is responsible for the
      phosphorylation of both CMP and deoxyCMP to the corresponding diphosphates. In
      glucose minimal medium the mutants grow at the same rate as the parental strain;
      however, they excrete large quantities of pyrimidines into the growth medium.
      Cytidine but not deoxycytidine has been identified among the excreted products.
      The mutant phenotype suggests that the physiological role of CMP kinase is that
      of rephosphorylating CMP arising from the breakdown of messenger ribonucleic
      acid. This proposed role of CMP kinase is supported by the fact that a cmk(-)
      mutant is much more sensitive to any partial impairment of cytidine 5'
      triphosphate synthetase than is the cmk(+) parent strain. The gene cmk has been
      located on the Salmonella chromosome at 38.5 min. No markers which can be
      cotransduced with cmk by phage P22 have been found.

PMID- 4373440
TI  - Fractionation of two diguanylic acids with different internucleotide linkages and
      its application for analyses of the synthetic products of ribonuclease T1 and
      spontaneous reaction.

PMID- 4373441
TI  - Electron spin resonance study of the interaction between heavy meromyosin and Mn2
      plus.

PMID- 4373442
TI  - Energization of NTP-NDP kinase by acid-base transition leading to ATP formation.

PMID- 4373443
TI  - Phosphorylation of endogenous hepatic proteins by adenosine 3',5'-monophosphate
      dependent protein kinase.

PMID- 4373444
TI  - Phosphodiesterase-phosphomonoesterases from Fusarium moniliforme. V. Mode of
      action on various nucleotides.

PMID- 4373445
TI  - Studies on mitochondrial and microsomal nucleoside diphosphatases of rat liver.

PMID- 4373446
TI  - Biochemical and topographical studies on the cell surface of Escherichia coli. I.
      Isolation and characterization of detergent-sensitive mutants.

PMID- 4373447
TI  - Kinetic studies on the inhibition of nucleoside diphosphate kinase by desdanine.

PMID- 4373448
TI  - Pyruvate kinase of Escherichia coli. Its role in supplying nucleoside
      triphosphates in cells under anaerobic conditions.

PMID- 4373449
TI  - Conversion of glucose and galactose to lipids by normal and phytohemagglutinin
      stimulated lymphocytes.

PMID- 4373450
TI  - Interactions between elongation factor tu-guanosine triphosphate and ribosomes
      and the role of ribosome-bound transfer RNA in guanosine triphosphatase reaction.

PMID- 4373451
TI  - Positional specificity of sn-glycerol 3-phosphate acylation during phosphatidate
      formation by rat liver microsomes.

PMID- 4373452
TI  - Structural studies on anti-inflammatory polysaccharides from Streptomyces
      fradiae.

PMID- 4373453
TI  - In vitro models for photosynthetic energy conversion.

PMID- 4373454
TI  - Adenylate cyclase activity in fibroblasts transformed by Kirsten or Moloney
      sarcoma viruses. Decreased activity and loss of response to prostaglandin E1.

PMID- 4373455
TI  - Characterization of the 4 S and 5 S forms of the estradiol receptor protein and
      their interaction with deoxyribonucleic acid.

PMID- 4373456
TI  - On the specificity of the binding of the estradiol receptor protein to
      deoxyribonucleic acid.

PMID- 4373457
TI  - Structural requirements for recognition of Escherichia coli initiator and non
      initiator transfer ribonucleic acids by bacterial T factor.

PMID- 4373458
TI  - Ecto-enzymes of the guinea pig polymorphonuclear leukocyte. I. Evidence for an
      ecto-adenosine monophosphatase, adenosine triphosphatase, and -p-nitrophenyl
      phosphates.

PMID- 4373459
TI  - Ecto-enzymes of the guinea pig polymorphonuclear leukocyte. II. Properties and
      suitability as markers for the plasma membrane.

PMID- 4373460
TI  - Purification and characterization of an inhibitor of elongation factor G
      dependent guanosine triphosphatase reaction of ribosomes from ribosome wash of
      Escherichia coli Q13.

PMID- 4373461
TI  - Rapid reciprocal changes in rat hepatic glycolytic enzyme and fructose
      diphosphatase activities following insulin and glucagon injection.

PMID- 4373462
TI  - Rapid reciprocal changes in rat tissue enzyme activities following epinephrine
      injection.

PMID- 4373464
TI  - Total reconstitution of copper-zinc superoxide dismutase.

PMID- 4373463
TI  - Structure of the carbohydrate units of IgA1 immunoglobulin. II. Structure of the
      O-glycosidically linked oligosaccharide units.

PMID- 4373466
TI  - The interaction of polypeptide components of human high density serum lipoprotein
      with detergents.

PMID- 4373465
TI  - Lipogenesis by acini from mammary gland of lactating rats.

PMID- 4373467
TI  - The decline of molecular activity of cytochrome oxidase during purification.

PMID- 4373468
TI  - Studies on ribonucleic acid ligase. Characterization of an adenosine triphosphate
      inorganic pyrophosphate exchange reaction and demonstration of an enzyme
      adenylate complex with T4 bacteriophage-induced enzyme.

PMID- 4373469
TI  - Ornithine cyclase (deaminating). II. Properties of the homogeneous enzyme.

PMID- 4373471
TI  - Studies on calciferol metabolism. IX. Renal 25-hydroxy-vitamin D3-1 hydroxylase.
      Involvement of cytochrome P-450 and other properties.

PMID- 4373470
TI  - Activation of hexose transport by concanavalin A in isolated brown fat cells.
      Effects of cell surface modification with neuraminidase and trypsin on lectin and
      insulin action.

PMID- 4373472
TI  - An iron-containing phosphatase induced by progesterone in the uterine fluids of
      pigs.

PMID- 4373473
TI  - Regulation of 25-hydroxyvitamin D3-1-hydroxylase in vivo.

PMID- 4373474
TI  - Formaldehyde dehydrogenase from human liver. Purification, properties, and
      evidence for the formation of glutathione thiol esters by the enzyme.

PMID- 4373475
TI  - Hydroxylysine-deficient skin collagen in a patient with a form of the Ehlers
      Danlos syndrome.
AB  - Two sibs with the Ehlers-Danlos syndrome, one of whom was shown to have
      hydroxylysine-deficient collagen, are described. In addition to the usual
      features of the Ehlers-Danlos syndrome (loose-jointedness and excessively
      stretchable, fragile, and bruisable skin), these patients had severe scoliosis
      and fragility of ocular tissues leading to rupture of the globe or retinal
      detachment. This combination of symptoms was tentatively classified as Ehlers
      Danlos syndrome, Type VI. The condition is inherited as an autosomal recessive.
      The activity of lysyl hydroxylase was present at a reduced level in fibroblasts
      cultured from the patient's skin.

PMID- 4373476
TI  - Extracorporeal circulation with and without magnesium. An experimental study.

PMID- 4373477
TI  - Studies on dispersed pancreatic exocrine cells. I. Dissociation technique and
      morphologic characteristics of separated cells.
AB  - A procedure for dissociation of the guinea pig pancreas into individual cells is
      described which employs enzymatic digestion with pure collagenase, chymotrypsin,
      and hyaluronidase, utilizes an interposed chelation of divalent cations by EDTA,
      and is terminated by gentle shearing. Yields of cells are 50-60%, based on DNA
      recovered. The population comprises approximately 95% exocrine cells, the
      remainder consisting of endocrine, duct, and vascular endothelial cells. The
      exocrine cells, though spherical, retain the structural attributes of their in
      situ counterparts, including differentiation of the plasmalemma into zones
      corresponding to the former apical and basal plasmalemma, polarized distribution
      of organelles indicated by fields of zymogen granules in the cytoplasm underlying
      the former apex, central location of the Golgi complex, and placement of the
      rough endoplasmic reticulum and nucleus in the former basal pole of the cell.
      Electron microscope study of the effects of individual treatments used during
      dissociation indicates that digestion of basement membrane and collagen is solely
      due to collagenase activity and that separation of desmosomes (and possibly of
      zonulae adherentes) results only from exposure to low [Ca(++)] and EDTA and is
      not effected by the enzymes used. Gap junctions are resistant to enzymes and
      EDTA; tight junctions resist enzyme treatment but undergo rearrangement upon
      exposure to EDTA. Both junctions require mechanical shear for complete cell
      separation. Neither chymotrypsin nor hyaluronidase produces visible alterations
      in stromal or junctional elements. Dissociation requires the concerted action of
      enzymes, chelation of divalent cations, and mechanical shear, since the
      individual treatments are alone ineffective.

PMID- 4373478
TI  - Food vacuole membrane growth with microtubule-associated membrane transport in
      Paramecium.
AB  - Evidence from a morphological study of the oral apparatus of Paramecium caudatum
      using electron microscope techniques have shown the existence of an elaborate
      structural system which is apparently designed to recycle digestive-vacuole
      membrane. Disk-shaped vesicles are filtered out of the cytoplasm by a group of
      microtubular ribbons. The vesicles, after being transported to the cytostome
      cytopharynx region in association with these ribbons, accumulate next to the
      cytopharynx before they become fused with the cytopharyngeal membrane. This
      fusion allows the nascent food vacuole to grow and increase its membrane surface
      area. The morphology of this cytostome-cytopharynx region is described in detail
      and illustrated with a three-dimensional drawing of a portion of this region and
      a clay sculpture of the oral apparatus of Paramecium. Evidence from the
      literature for the transformation of food vacuole membrane into disk-shaped
      vesicles both from condensing food vacuoles in the endoplasm and from egested
      food vacuoles at the cytoproct is presented. This transformation would complete a
      system of digestive vacuole membrane recycling.

PMID- 4373479
TI  - Effects of cytochalasin B on the response of toad urinary bladder to vasopressin.
AB  - A combined physiological and morphological study of the effects of cytochalasin B
      (CB) on the toad urinary bladder has been carried out. CB inhibits the hydro
      osmotic response to vasopressin without altering basal water permeability or
      diffusion, or the increase in (3)H(2)O diffusion observed after hormone addition.
      Although CB increases [(22)Na]-, [(36)Cl]-, and [(14)C]urea fluxes, and decreases
      transepithelial potential, no alteration in basal short-circuit current, the
      vasopressin-induced increase in this parameter, or [(14)C]inulin permeability
      occurs. In the absence of hormone, CB does not markedly alter the structure of
      the toad bladder. However, in the presence of vasopressin, CB induces the
      formation of large intracellular vacuoles. These results suggest a possible
      coupling of solute and water movement across the tissue.

PMID- 4373480
TI  - Analysis of the pinocytic process in rat kidney. I. Isolation of pinocytic
      vesicles from rat kidney cortex.
AB  - Pinocytosis was induced in rat kidney by exposure to horseradish peroxidase
      (HRP). Pinocytic vesicle preparations were enriched after homogenization of
      kidney cortex by differential centrifugation and free-flow electrophoresis with
      HRP as an exogenous marker. Vesicles were identified by enzymatic analysis and by
      electron microscopy, including specific staining procedures. Typical brush-border
      enzymes such as alkaline phosphatase, aminopeptidase, 5'-nucleotidase, lysosomal
      acid phosphatase, and mitochondrial succinic dehydrogenase were reduced in the
      vesicular fraction, compared to the kidney cortex homogenate. Glucose-6
      phosphatase and Na(+)-K(+)-ATPase were only slightly increased in the fraction.
      These results indicate that preparations of pinocytic vesicles from rat kidney
      cortex can be enriched. They have biochemical characteristics that differ from
      those of the cell organelles and membranes previously purified from renal tissue.

PMID- 4373481
TI  - Metabolic cooperation in cell culture: studies of the mechanisms of cell
      interaction.

PMID- 4373482
TI  - Release of cytoplasmic enzymes into culture fluid.

PMID- 4373483
TI  - In vitro response of goldfish (Carassius auratus L.) dermal melanophores to
      cyclic 3',5'-nucleotides, nucleoside 5'-phosphates and methylxanthines.

PMID- 4373485
TI  - Cell cycle dependent modulations of the surface membrane of normal and SV40 virus
      transformed 3T3 cells.

PMID- 4373484
TI  - Effect of cAMP on nucleoside metabolism. II. Cell cycle dependence of thymidine
      transport.

PMID- 4373486
TI  - Cellular binding of 3H-cytochalasin B.

PMID- 4373487
TI  - A temperature-sensitive cell cycle mutant of the BHK cell line.

PMID- 4373489
TI  - Agglutination by concanavalin A of normal chick embryo fibroblasts treated by 5
      bromodeoxyuridine (BrdU).

PMID- 4373488
TI  - Concanavalin A and the initiation of thymic lymphoblast DNA synthesis and
      proliferation by a calcium-dependent increase in cyclic GMP level.

PMID- 4373490
TI  - Editorial: Hypothalmic neurohumors and pituitary tumors.

PMID- 4373491
TI  - Bile acid kinetics in relation to sex, serum lipids, body weights, and
      gallbladder disease in patients with various types of hyperlipoproteinemia;.
AB  - Bile acid kinetics were determined in 15 normolipidemic and 61 hyperlipidemic
      subjects with the aid of [(14)C]cholic acid and [(3)H]chenodeoxycholic acid. The
      diet was standardized and of natural type. The total bile acid formation was
      within normal limits in patients with hyperlipoproteinemia types IIa and IIb. On
      the average the production of cholic acid (C) represented less than 50% of the
      total bile acid synthesis in both groups. The corresponding value recorded for
      the controls was 64+/-2% (mean+/-SEM). The synthesis of C in hyperlipoproteinemia
      type IIa was significantly below normal. Of the 27 patients with the type IV
      pattern, 18 had a synthesis of C and C + chenodeoxycholic acid (CD) that exceeded
      the upper range recorded for the controls. In these subjects the C formation
      represented 73+/-3% of the total bile acid synthesis. Similar findings were also
      encountered in the five patients with the type V lipoprotein pattern studied. The
      bile acid pool size of the 11 patients with hyperlipoproteinemia type IV, who had
      been cholecystectomized or suffered from cholelithiasis, was 900 mg smaller on
      the average than that of the other subjects with the same type of
      hyperlipoproteinemia. However, the pool size in the former subjects still tended
      to be higher than that of the control subjects without evidence of gallbladder
      "disease". In all groups of subjects the formation of bile acids tended to be
      higher in the male than in the female subjects. Bile acid synthesis showed no
      linear correlation to actual body weight, relative body weight, or body surface
      area. A moderate weight reduction in five patients (one with type IIb and four
      with type IV pattern) was followed by a 50% reduction of the C and CD synthesis.

PMID- 4373492
TI  - The secondary structure of human Hageman factor (factor XII) and its alteration
      by activating agents.
AB  - Hageman factor (factor XII) is activated by exposure to surfaces such as glass or
      by solutions of certain compounds, notably ellagic acid. Changes in the structure
      of Hageman factor accompanying activation have been examined in this study by
      circular dichroism spectroscopy. The spectrum of unactivated Hageman factor in
      aqueous solutions suggests that its conformation is mainly aperiodic. Various
      perturbants altered the conformation of Hageman factor in differing ways,
      demonstrating the sensitivity of Hageman factor to its environment. After
      activation of Hageman factor with solutions of ellagic acid, a negative trough
      appeared in the region of the circular dichroism spectrum commonly assigned to
      tyrosine residues, along with other minor changes in the peptide spectral region.
      Some of these changes are similar to changes that occurred upon partial
      neutralization of the basic residues at alkali pH. Activation of Hageman factor
      by adsorption to quartz surfaces (in an aqueous environment) also produced
      changes similar to those in the ellagic acid-activated Hageman factor, including
      the negative ellipticity in the tyrosine region. These observations suggest that
      the activation process may be related to a change in status of some of the basic
      amino acid residues, coupled with a specific change in the environment of some
      tyrosine residues. The importance of these changes during the activation process
      remains to be determined. The sensitivity of Hageman factor to its environment is
      consistent with the view that the initiation of clotting by exposure of plasma to
      appropriate agents is brought about by alterations in the conformation of Hageman
      factor that occur in the apparent absence of Fletcher factor or other recognized
      clotting factors.

PMID- 4373493
TI  - Superficial and deep juxtaglomerular apparatus renin activity of the rat kidney.
      Effect of surgical preparation and NaCl intake.
AB  - The intrarenal gradient of renin activity was determined in rats by using
      superficial (S) and deep (D) cortical juxtaglomerular apparatuses (JGA's),
      identified and microdissected after silicone-rubber compound injection.
      Angiotensin generated from single JGA's using partially purified sheep renin
      substrate was quantified by rat bioassay. When, in rats on a normal NaCl diet,
      silicone-rubber was injected into a carotid artery, alone or with abdominal aorta
      catheterization, S:D renin activity ratios were 1.18+/-0.08 (SEM) and 1.21+/
      0.12, respectively. The S:D renin activity ratios obtained when silicone-rubber
      was injected into the abdominal aorta (2.52+/-0.09) or a chronic carotid artery
      catheter (3.44+/-0.40) were significantly higher (P < 0.001). The lower S:D renin
      activity ratios after carotid artery manipulation were due to significantly
      higher D-JGA renin activities. This increased D-JGA renin activity and the lack
      of a renin gradient appear to be related to acute carotid artery manipulation.
      Alterations in JGA renin activity were examined relative to NaCl intake. 2 wk
      after high-NaCl diet the absolute net renin activity decreased (P < 0.001) more
      in S (5.84+/-0.11 ng AI.JGA(-1).h(-1)) than D (1.73+/-0.06 ng AI.JGA(-1).h(-1))
      JGA's, and the intrarenal renin gradient was lost (S:D-JGA renin activity, 1.00+/
      0.07), as compared to the regular NaCl diet. 2 wk of a low-NaCl diet resulted in
      a greater (P < 0.01) increase in S (14.28+/-1.47 ng AI.JGA(-1).h(-1)) than D
      (9.62+/-1.19 ng AI.JGA(-1).h(-1)) JGA renin activity and a renin gradient (S:D
      JGA renin activity) of 1.75+/-0.12. These results demonstrate that NaCl intake
      clearly influences total JGA renin content and may also affect the relative
      intrarenal distribution of renin activity.

PMID- 4373495
TI  - Letter: Dynamics and thermodynamics of axial ligation in metalloporphyrins. 3.
      Effects of molecular interaction of ferric porphyrins with an aromatic acceptor.

PMID- 4373494
TI  - Glucagon secretion from the perfused rat pancreas. Studies with glucose and
      catecholamines.
AB  - The isolated in situ perfused rat pancreas was used to study glucose and
      catecholamine control of glucagon secretion, and to investigate the possible role
      of endogenous cyclic AMP as a mediator of this secretory process. When perfusate
      glucose was acutely dropped from 100 to 25 mg/100 ml, glucagon was released in a
      biphasic pattern with an early spike and a later plateau-like response. 300
      mg/100 ml glucose suppressed glucagon secretion to near the detection limit of
      the radioimmunoassay (15 pg/ml). When perfusate glucose was dropped from 300 to
      25 mg/100 ml, a delayed, relatively small peak occurred suggesting persisting
      alpha cell suppression by prior high glucose exposure. 2-Deoxy d-glucose
      stimulated glucagon secretion and inhibited insulin secretion. Glucagon was
      secreted in a biphasic pattern in response to both 2.7 x 10(-7) M epinephrine and
      norepinephrine. The glucagon response to epinephrine was markedly suppressed by
      glucose at 300 mg/100 ml, and the biphasic response pattern was obliterated.
      Glucose evoked a two-phase insulin secretory pattern, and the second phase was
      markedly and rapidly inhibited by epinephrine. Pancreases were perfused with
      glucose at 300 mg/100 ml which was then lowered to 80 mg/100 ml. 5 min later,
      epinephrine was infused and definite blunting of the first-phase spike occurred.
      10 mM theophylline produced modest rapid uniphasic stimulation of glucagon
      release, and, in addition, caused enhancement of epinephrine-stimulated glucagon
      release. An inhibitory influence upon epinephrine-stimulated glucagon was
      observed as well. Insulin secretion was stimulated by 10 mM theophylline, and
      this stimulation was inhibited by epinephrine.

PMID- 4373496
TI  - Letter: Lanthanide porphyrin complexes. A potential new class of nuclear magnetic
      resonance dipolar probe.

PMID- 4373497
TI  - Growth and development of children maintained on total parenteral nutrition in
      the neonatal period.

PMID- 4373498
TI  - AMWA--six decades of progress (in the serivice of women in medicine).

PMID- 4373499
TI  - Future aspects of the American Medical Women's Association.

PMID- 4373500
TI  - Malnutrition and infection. Malaria, cholera and influenza in Africa.

PMID- 4373501
TI  - Edith L. Potter, M.D.--pathologist.

PMID- 4373502
TI  - Letter: To: Women concerned about health care.

PMID- 4373503
TI  - Testes structure in normal and parthenogenetic turkeys.

PMID- 4373504
TI  - A heat-digestible cell-immunoadsorbent made by coupling hapten to gelatin.

PMID- 4373505
TI  - Drug induced depression.

PMID- 4373506
TI  - Amoebiasis with pericardial involvement.

PMID- 4373507
TI  - The post-mortem diagnosis of Japanese encephalitis.

PMID- 4373508
TI  - Seminars from Riley Children's Hospital. Recent developments in treatment of
      childhood cancer. II.

PMID- 4373509
TI  - [Clinical and pathological studies on so-called sclerosing angioma of the lung].

PMID- 4373510
TI  - [Clinical application of angiotensin II analogue (1-sarcosine, 8-isoleucine
      angiotensin II) (author's transl)].

PMID- 4373511
TI  - [Studies on the lipoprotein metabolism--changes of lipids, lipoprotein and
      apolipoprotein after heparin-induced lipolysis (author's transl)].

PMID- 4373512
TI  - [Symposium on gastrointestinal hormones. Action mechanism of gastrin (author's
      transl)].

PMID- 4373513
TI  - Pseudomonas tracheobronchitis. The use of systemic gentamicin and polymyxin-B
      aerosol.

PMID- 4373514
TI  - Fasting hypoglycemia. Diazoxide as a test for endogenous insulin release.

PMID- 4373515
TI  - The primary hyperlipoproteinemias.

PMID- 4373516
TI  - Intracellular actions of 5-hydroxytryptamine on the bivalve myocardium. II.
      Cyclic nucleotide-dependent protein kinases and microsomal calcium uptake.

PMID- 4373517
TI  - Improved culture techniques and sporulation medium for enterotoxin production by
      Clostridium perfringens type A.

PMID- 4373518
TI  - Characteristics of enterotoxigenic Clostridium perfringens type A isolated from
      cattle and chickens.

PMID- 4373519
TI  - Circular resection of the trachea for malignant and benign diseases.

PMID- 4373520
TI  - [Facial paralysis and parotid tumefactions].

PMID- 4373521
TI  - [Necrotizing ethmoiditis caused by anaerobic bacteria. Apropos of a case].

PMID- 4373522
TI  - Formation of phospholipase C and theta-haemolysin in pre-reduced media in batch
      anc continuous culture of Clostridium perfringens type A.

PMID- 4373524
TI  - Ultrastructure of a marine Thiobacillus.

PMID- 4373523
TI  - Isoprenoid alcohol kinase--a third butanol-soluble enzyme in Klebsiella aerogenes
      membranes.

PMID- 4373525
TI  - Growth inhibition of Acetobacter aceti by L-threonine and l-Homoserine: the
      primary regulation of the biosynthesis of amino acids of the aspartate family.

PMID- 4373526
TI  - The effects of beta-galactosidase activity and cyclic AMP on lactose-accelerated
      death.

PMID- 4373527
TI  - Inhibition by ethidium bromide of the establishment of infection by murine
      sarcoma virus.

PMID- 4373528
TI  - The effect of isatin beta thiosemicarbazone (IBT)-related compounds on IBT
      resistant and on IBT-dependent mutants of vaccinia virus.

PMID- 4373529
TI  - Aminoacylation of RNA from several viruses: amino acid specificity and
      differential activity of plant, yeast and bacterial synthetases.

PMID- 4373530
TI  - The cytopathic effect of herpes simplex virus on HEp-2 cells as shown by scanning
      electron microscopy.

PMID- 4373531
TI  - Peripheral serotonin antagonists: failure to antagonize serotonin in brain areas
      receiving a prominent serotonergic input.

PMID- 4373532
TI  - Correlation between ultrastructural and electrophysiological signs of
      degeneration in optic nerve terminals of the cat's lateral geniculate nucleus.

PMID- 4373533
TI  - Cyclic AMP and amine effects on phosphorylation of specific protein in abdominal
      ganglion of Aplysia californica; localization and kinetic analysis.

PMID- 4373534
TI  - Activity patterns of catecholamine-containing pontine neurons in the dorso
      lateral tegmentum of unrestrained cats.

PMID- 4373535
TI  - Antifacilitating and simple following responses in a single motoneuron.

PMID- 4373536
TI  - The uptake of 36C1 into astrocytes in tissue culture by a potassium-dependent,
      saturable process.

PMID- 4373537
TI  - The characterization of sphingolipids from neurons and astroglia of immature rat
      brain.

PMID- 4373538
TI  - Phosphatidyl inositol turnover in muscle membranes following denervation.

PMID- 4373539
TI  - Hydrolytic enzyme activities in the developing chick central and peripheral
      nervous systems.

PMID- 4373540
TI  - Preparation of synaptosomes and vesicles with sodium diatrizoate.

PMID- 4373541
TI  - The cytotoxicity of D-galactosamine in cat spinal cord.

PMID- 4373542
TI  - The ultrastructure of retinula cell endings in the compound eye of the crayfish.

PMID- 4373543
TI  - Interneurons of the sympathetic ganglia, in organotypic culture. A suggestion as
      to their function, based on three types of study.

PMID- 4373544
TI  - The fate of the axon and its terminal in the Pacinian corpuscle following sciatic
      nerve section.

PMID- 4373545
TI  - Neuroglial cells in the cerebral cortex of rats from young adulthood to old age:
      an electron microscope study.

PMID- 4373546
TI  - Synaptic inhibition in pyramidal tract neurons: membrane potential and
      conductance changes evoked by pyramidal tract and cortical surface stimulation.

PMID- 4373547
TI  - Motor organization and generation of rhythmic feeding output in buccal ganglion
      of Pleurobranchaea.

PMID- 4373548
TI  - Effects of projected cortical epileptiform discharges on neuronal activities in
      cat VPL. I. Interictal discharge.

PMID- 4373549
TI  - Active transport of thiamine from rat small intestine.

PMID- 4373550
TI  - Effect of amino acid supplement on liver lipid content and lipid metabolism of
      rats fed a nonprotein diet.

PMID- 4373551
TI  - Purification and properties of quinolinate phosphoribosyltransferase from the
      "Shiitake" mushroom (Lentinus edodes).

PMID- 4373552
TI  - Characteristics of quinolinate phosphoribosyltransferase from the "Shiitake"
      mushroom (Lentinus edodes).

PMID- 4373553
TI  - Preventive effect of riboflavin 2',3',4',5'-tetrabutyrate on inactivation of rat
      liver microsomal enzymes induced by carbon tetrachloride.

PMID- 4373554
TI  - The mechanism of action of oestrogen in the human female.

PMID- 4373555
TI  - Swellings of the salivary glands. Part II, neoplasms.

PMID- 4373557
TI  - [Surgery of thyroid neoplasms].

PMID- 4373556
TI  - [Experimental otitis interna of various origins. Comparison between disorders
      caused by virus infections, drug intoxication and allergic reactions].

PMID- 4373558
TI  - Enzyme patterns in non-neoplastic and spontaneously transformed tissue culture
      cells: a histochemical and biochemical study.

PMID- 4373559
TI  - Cystic adenoma of a minor salivary gland: a histochemical study.

PMID- 4373560
TI  - Extensive calcification in the stroma of a primary hepatic carcinoma.

PMID- 4373561
TI  - Microsporidan infection of Simulium damnosum in West Africa.

PMID- 4373562
TI  - [Decomposition and stabilization of aminoglycol alkanesulfonates (author's
      transl)].

PMID- 4373564
TI  - Letter: Bioavailability of digoxin in presence of antacids.

PMID- 4373563
TI  - Synthetic procedures for deuterium-labeled acetylcholine perchlorates.

PMID- 4373565
TI  - Letter: Nonaqueous titration of procainamide hydrochloride.

PMID- 4373566
TI  - Renin and angiotensin-like levels in foetal, new-born and adult sheep.
AB  - 1. Plasma renin (measured as rate of formation of angiotensin I ng/ml.hr(-1) in
      the presence of added substrate at pH 7.5 and 37 degrees C) was much lower in
      recently nephrectomized foetal, new-born and older lambs than in intact siblings
      or other similar lambs.2. Angiotensin II-like concentrations were measured using
      a superfusion technique in an extracorporeal circuit. Resting concentrations in
      acute experiments under anaesthesia were deduced by comparison of carotid blood
      of intact lambs with that from recently nephrectomized lambs.3. Angiotensin II
      like activity (mean +/- S.E. of mean, 315 +/- 117 pg/ml.) was readily detectable
      in foetal blood at 123-138 days gestation. The highest concentrations (mean +/-
      S.E. of mean 839 +/- 96 pg/ml.) were found in lambs less than 8 hr old, delivered
      vaginally. The lowest concentrations of angiotensin II-like activity occurred in
      lambs delivered by Caesarean section (mean +/- S.E. of mean < 123 +/- 12 pg/ml.).
      Concentrations declined with post-natal age.4. Hypovolaemia as a result of
      haemorrhage evoked an increase in angiotensin II-like concentrations in foetus,
      new-born lambs and adult sheep. The greatest increase of angiotensin-like
      concentrations was seen in new-born lambs. This rise was associated with increase
      of plasma renin.5. The rise of arterial pressure during bilateral carotid
      occlusion in new-born lambs was accompanied by an increase of angiotensin II-like
      concentration.6. It is concluded that the renin-angiotensin system is functional
      and can be stimulated during intra-uterine life. The increase of angiotensin II
      like concentration following parturition is probably transient and associated
      with the trauma of delivery. This contrasts with observations made in the rabbit
      which suggest that full functional maturity of the renin angiotensin system is
      delayed until the second week of life.

PMID- 4373567
TI  - Synapse formation during embryogenesis on ganglion cells lacking a periphery.
AB  - 1. The development of transmission was studied in chick ciliary ganglia that had
      been deprived of their periphery during early embryonic development.2.
      Peripherally deprived neurones in the ganglion differentiate in normal numbers
      and send functional axons into the post-ganglionic nerve.3. Ganglion cells
      lacking a periphery follow the normal developmental sequence sending out
      transient dendrites at the time ganglion cell synapses are formed, and later
      retracting them when calyces appear.4. Synapses, which appear functionally and
      ultrastructurally normal, form on all ganglion cells at the normal time and
      transmission is normal until Stage 34. Therefore information from the periphery
      is not required for ganglion cell synapse formation per se.5. From Stages 35 to
      38 most cells die, so that only 8% of the original number of cells remain in the
      operated ganglion. Transmission fails in many cells during this same time, but
      precedes cell loss by only a short time, so that deafferentation probably does
      not contribute substantially to cell death.6. Both ciliary and choroid cells
      achieve full cytologic differentiation and are distinct from each other,
      indicating that the periphery is not required for the elaboration of the
      distinctive characteristics of these cells. Presynaptic fibres also differentiate
      into typical bouton as well as calyciform endings. Therefore, the type of
      preganglionic ending does not depend on ganglion cells establishing proper
      peripheral contacts.7. It has not been possible to ascertain whether ganglion
      cell specificity is affected by the periphery.8. Peripheral removal affects
      ganglion cell migration, so that two ganglia are formed. Approximately half of
      the cells migrate into the remnant optic cup forming a second misplaced ganglion.
      Ciliary and choroid cells occur in both ganglia and these cells go through the
      typical sequence of events described above.

PMID- 4373568
TI  - Synaptic transmission and cell death during normal ganglionic development.
AB  - 1. During normal embryonic development of the chick ciliary ganglion, cell death
      over a 4-day period (Stages 35-39) reduces the number of ganglion cells by half,
      from 6500 to 3200. Both ciliary and choroid populations are affected by
      approximately the same amount.2. Previous to cell death, preganglionic fibres
      form functional synapses on all ganglion cells, indicating that synapses form on
      cells which are destined to die.3. Shortly before the period of cell death, there
      is a failure of transmission in approximately half the cells. Some evidence
      suggests that transmission failure in at least some of the cells is of
      preganglionic origin.4. Cell death is nearly synchronous with the establishment
      of peripheral connexions by ganglion cells, at least with respect to the ciliary
      population which forms functional synapses with iris muscle. This implies that
      those cells which die do so because they have failed to form adequate peripheral
      connexions.5. It is suggested that many of the cells in which transmission has
      failed die, bringing transmission through the ganglion back to 100%. However,
      transmission failure appears to be a transitory phenomenon in other cells which
      survive and probably results from death of their preganglionic elements.
      Restoration of transmission would then be brought about by the formation of new
      or more effective synapses by surviving preganglionic fibres.

PMID- 4373569
TI  - The effects of caffeine on sodium transport, membrane potential, mechanical
      tension and ultrastructure in barnacle muscle fibres.
AB  - 1. The effects of graded concentrations of caffeine on the Na efflux were
      investigated. External application of 10 mM caffeine usually caused a biphasic
      response, viz. a fall, followed by a rise in the Na efflux. 1 and 5 mM caffeine
      usually caused stimulation. Only the stimulatory phase of this response depended
      on the presence of external Ca(2+).2. Internal application of 100 mM caffeine
      caused a small rise in the Na efflux, the magnitude of which was independent of
      external Ca(2+) and comparable to that obtained with external application of 1 mM
      caffeine. This action, however, could be greatly augmented by pre-treating the
      fibre with 5 x 10(-5)M ouabain.3. The rise in Na efflux caused by external
      application of 10 mM caffeine could be greatly augmented by pre-treating the
      fibre with 5 x 10(-5)M ouabain. The observed stimulatory response was biphasic,
      more so in the absence of external Ca(2+). Restoration of external Ca(2+)
      following the onset of the second stimulatory phase resulted in further rise of
      the Na efflux. Measurements of the Na efflux during treatment with graded
      concentrations of ouabain and 10 mM caffeine showed that the rate coefficient for
      Na efflux varied with the ouabain concentration in the range 10(-8)-10(-4)M.
      Measurements of the ouabain-insensitive Na efflux before and during treatment
      with 10 mM caffeine in bathing media containing varying concentrations of Ca,
      disclosed the existence of two Ca(2+)-thresholds, one in the 0-2.5 mM range and
      the other in the 12.5-15 mM range.4. Comparisons were made between the effects on
      the Na efflux of 10 mM caffeine followed by external acidification, and external
      acidification, followed by 10 mM caffeine. The magnitude of the response of the
      ouabain-insensitive Na efflux to external acidification before treatment with 10
      mM caffeine was greater than that found when external acidification followed
      external application of the alkaloid. It also was considerably greater than that
      of the response to external application of 10 mM caffeine before external
      acidification.5. External application of 10 mM procaine prevented 10 mM caffeine
      from stimulating the Na efflux, and from inducing contractures. Internal
      application of 100 mM-EGTA reduced the response of the Na efflux to 10 mM
      caffeine, and also prevented the fibre from contracting. External application of
      10(-4)M diphenylhydantoin reduced the response of the Na efflux to 10 mM caffeine
      but failed to prevent the development of contractures.6. Internal application of
      0.05 M-cGMP, cAMP or its dibutyryl derivative caused a large rise in the Na
      efflux. The magnitude of the effects observed in ouabain-poisoned fibres was
      often greater than that in unpoisoned fibres. Internal application of 2.5
      units/ml. phosphodiesterase beforehand failed to reduce the magnitude of the
      stimulatory response to injected cyclic nucleotides. Injected phosphodiesterase
      also failed to reduce the response of the Na efflux to 10 mM caffeine.7. External
      application of 10 mM caffeine to unpoisoned and ouabain-poisoned fibres caused a
      fall of approximately 10 mV in the membrane potential. In unpoisoned fibres this
      effect was transitory. The response of the membrane potential to internal
      application of graded concentrations of CaCl(2) was biphasic. When low
      concentrations of CaCl(2) were used the membrane potential underwent a small rise
      but when high concentrations were used the opposite was found. These results
      could not be repeated with graded concentrations of MgCl(2).8. The effects of
      graded concentrations of caffeine on tension development were also studied.
      Strong contractures were observed with caffeine concentrations as low as 4 mM,
      while peak tetanus tension was usually exceeded with 7-8 mM concentrations. The
      tension-external Ca(2+) curve was sigmoidal in shape.9. Electron microscopic
      studies showed that 10 mM caffeine in ASW caused little or no distension and
      disorganization of cisternal fine structure. Such structural changes, however,
      were far more pronounced in fibres suspended in Ca(2+)-free ASW and then treated
      with 10 mM caffeine in Ca(2+)-free ASW. Fibres soaked in Ca(2+)-free ASW had
      ruptured mitochondria and mitoplasts, whereas those additionally treated with 10
      mM caffeine had relatively intact mitochondria.10. The main conclusions drawn
      from this work are: (i) that caffeine stimulates the ouabain-insensitive Na
      efflux (and inhibits the transport enzyme) by raising the internal free Ca(2+)
      concentration; (ii) that in the presence of inhibition of the transport enzyme,
      the magnitude of the stimulatory response to 10 mM caffeine depends not only on
      the external Ca(2+) concentration but mainly on the residual level of activity of
      the transport enzyme; (iii) that the Ca(2+)-sensitive and CO(2)-sensitive
      components of the ouabain-insensitive Na efflux, though not the same, may overlap
      at the level of the plasma membrane or share a common metabolic step away from
      the membrane; (iv) that cyclic nucleotides participate in the control of the
      magnitude of the ouabain-insensitive Na efflux, and that the phosphodiesterase
      system under the present experimental conditions does not seem to be involved in
      the mechanism underlying the stimulatory action of caffeine; (v) that the
      membrane potential changes caused by caffeine fail to explain the stimulatory
      response of the Na efflux, as well as contracture of these fibres; (vi) that the
      contractile machinery in these fibres is considerably more sensitive to caffeine
      than that in vertebrate muscle and the muscles of other arthropods, and (vii)
      that the Ca(2+) released by the sarcoplasmic reticulum which leads to a biphasic
      response of the Na efflux is the result of cisternal disorganization caused by
      caffeine.

PMID- 4373571
TI  - Quantitative and graphic analysis of prosthetic treatment for "nasalance" in
      speech.

PMID- 4373570
TI  - On the role of vasopressin and angiotensin in the development of irreversible
      haemorrhagic shock.
AB  - 1. Long-lasting haemorrhagic hypotension (4.5 hr at 35 mmHg) leading to
      irreversible haemorrhagic shock, has been studied in normal dogs, in dogs treated
      with a bradykinin potentiating nonapeptide (BPP(9a)), which blocks the conversion
      of angiotensin I to angiotensin II, and in dogs with experimental chronic
      diabetes insipidus (DI dogs). BPP(9a) was given by I.V. injection before the
      start of bleeding (BPP pre-treated group), 45 min after blood pressure had
      reached 35 mmHg (BPP early treated group) or 2 hr after blood pressure had
      reached 35 mmHg (BPP late-treated group). After retransfusion of blood all dogs
      were allowed to recover and observed for a further period of 3 days.2. Untreated
      control dogs developed haemorrhagic shock with tachycardia, low cardiac output,
      low total peripheral conductance and low stroke volume. All died within 24 hr of
      retransfusion, with pathological lesions typical of irreversible haemorrhagic
      shock.3. BPP pre-treated dogs developed haemorrhagic shock with bradycardia
      (during early shock), high cardiac output, high peripheral vascular conductance
      and high stroke volume when compared with the untreated controls. All pre-treated
      animals survived the 3 day observation period. They were then killed and on post
      mortem showed no signs of irreversible haemorrhagic shock.4. BPP early-treated
      animals behaved like controls before BPP, but like pre-treated animals after the
      drug. Only one out of eight died within the 3 day observation period.5. BPP late
      treated dogs behaved like controls before BPP. They responded to the drug with a
      rise in cardiac output, peripheral vascular conductance and stroke volume, and
      with a fall in heart rate. These responses were, however, short-lived. Four out
      of these eight animals died within the 3 day observation period, with lesions of
      irreversible haemorrhagic shock.6. DI dogs developed haemorrhagic shock with
      tachycardia (like controls), but with high cardiac output and peripheral vascular
      conductance (like BPP pre-treated dogs). The stroke volume of DI dogs was
      intermediate between those of controls and pre-treated groups. All six dogs
      survived the 3 day observation period.7. BPP(9a) had no measurable effect on the
      course of endotoxic shock.8. It is suggested that the normally severe
      vasoconstriction of the mesenteric vascular bed, which is thought to be
      responsible for irreversible haemorrhagic shock, is absent or attenuated in the
      absence of vasopressin or angiotensin. The consequences of this on the
      development of irreversibility are discussed.

PMID- 4373572
TI  - [Semantics of the radiographic picture. Semantics and teaching : teaching about
      the picture, teaching using the picture].

PMID- 4373573
TI  - Wilms' tumor and neuroblastoma. Survey of a ten year experience.

PMID- 4373574
TI  - Relationship between Epstein-Barr virus-determined complement-fixing antigen and
      nuclear antigen detected by anticomplement fluorescence.

PMID- 4373575
TI  - A preliminary investigation into the role of immunity in modifying the blood-
      borne spread of chemically induced rat sarcomas.

PMID- 4373576
TI  - Interferon inhibition of autogenously induced virions (C particles) in
      synchronized L-929 cell cultures.

PMID- 4373578
TI  - Naturally occurring sarcoma virus of the BALB/cCr mouse.

PMID- 4373577
TI  - A complement-fixation test for the bovine leukemia (C-type) virus.

PMID- 4373579
TI  - Inhibition of murine sarcoma development by deoxycorticosterone acetate.

PMID- 4373580
TI  - Detection of mouse mammary tumor virus in cat kidney cells infected with purified
      B particles from RIII milk.

PMID- 4373581
TI  - Atypical C particles in adenocarcinomas induced by implantation of FUKU cells.

PMID- 4373582
TI  - Type-C virus particles in a feline angioma: a case report.

PMID- 4373584
TI  - Renal malignant histiocytoma.

PMID- 4373583
TI  - Belated recognition of adrenocorticotropic hormone-producing tumors in post
      adrenalectomized Cushing's syndrome.

PMID- 4373585
TI  - Serological indication of canine distemper and of infectious canine hepatitis in
      wolves (Canis lupus L.) in northern Canada.

PMID- 4373586
TI  - Relationship of pulmonary particulates in English sparrows to gross air
      pollution.

PMID- 4373587
TI  - Survey of diseases in free-living California sea lions.

PMID- 4373588
TI  - Vulvovaginitis in wildebeest caused by the virus of infectious bovine
      rhinotracheitis.

PMID- 4373589
TI  - Successful medical adrenalectomy with amino-glutethimide. Role of altered drug
      metabolism.

PMID- 4373590
TI  - Management of hyperlipidemias.

PMID- 4373591
TI  - Effect of several proteinase inhibitors on renin reaction.

PMID- 4373592
TI  - Clinical applications of synthetic angiotensin II analogue.

PMID- 4373594
TI  - Effects of angiotensin on catecholamine metabolism in rat.

PMID- 4373593
TI  - Pressor responsiveness, hemodynamics and plasma renin activity in essential
      hypertension.

PMID- 4373595
TI  - Analysis of relationship between renin-angiotensin system and blood pressure in
      experimental hypertension induced by kidney extract.

PMID- 4373596
TI  - The kidney factors in the production of acute hypertensive vascular lesions.

PMID- 4373597
TI  - Effect of Ca on renin release in vitro and in vivo.

PMID- 4373598
TI  - [On biliary excretion of minocycline (minomycin 'Lederle') injected by
      intravenous drip (author's transl)].

PMID- 4373599
TI  - Renin content in subcellular fractions of kidney extract of renovascular
      hypertensive rats.

PMID- 4373600
TI  - [Primary hypothyroidism associated with isolated ACTH deficiency].

PMID- 4373601
TI  - [Congestive heart failure].

PMID- 4373602
TI  - [Clinical studies on the effects of prostaglandin A2 on water-electrolyte
      metabolism and the renin-angiotensin-aldosterone system].

PMID- 4373603
TI  - Detection of alpha-fetoprotein in mice infected with mouse hepatitis virus.

PMID- 4373604
TI  - Presence of glucosyl ceramide and lactosyl ceramide in human intracranial
      tumours.

PMID- 4373605
TI  - Properties of hemolytic streptococci grown in glucose-containing medium.

PMID- 4373606
TI  - [Treatment of liver cancer with oral administration of N-(2'-furanidyl)-5
      fluorouracil (FT207) (author's transl)].

PMID- 4373607
TI  - [ACTH radioimmunoassay kit].

PMID- 4373608
TI  - Separation of the contributions of voluntary and vibratory activation of motor
      units in man by cross-correlograms.

PMID- 4373609
TI  - [Adenosin 3', 5'-monophosphate levels in the lung and bronchi and their
      fluctuation with special reference to tracheobronchial hypersensitivity in
      bronchial asthma].

PMID- 4373610
TI  - [Increase of lipoprotein occuring simultaneously with retinal damage through
      intake of an oral contraceptive (author's transl)].

PMID- 4373611
TI  - [Ways of improvement of antibiotic therapy of pyocyanic infection].

PMID- 4373612
TI  - [New theories of the pathogenesis of diabetic neuropathies].

PMID- 4373613
TI  - [Pathogenesis of ulcer disease and adrenal cortex].

PMID- 4373614
TI  - The ubiquitous effects of histamine phosphate on the atria of the albino mouse.

PMID- 4373615
TI  - Hexachlorophene-induced changes in central and peripheral myelinated axons of
      developing and adult rats.

PMID- 4373616
TI  - Starch estimation in leaf tissue--a comparison of results using six methods.

PMID- 4373617
TI  - The proximate chemical composition and the amino acid content of some Nigerian
      oil seeds.

PMID- 4373618
TI  - The metabolic consequences of trauma.

PMID- 4373620
TI  - The valve action of intensity receptor.

PMID- 4373619
TI  - Regulation of size and birefringence of the in vivo mitotic apparatus.

PMID- 4373621
TI  - Localized oscillations in neural networks. I. General considerations with
      nonlinear differential equations.

PMID- 4373623
TI  - A new technique for cannulating lymphatic vessels: experience in 150 extremities.

PMID- 4373622
TI  - Endoscopy of the thoracic duct (lymphoscopy) via the external jugular vein in
      dogs.

PMID- 4373624
TI  - Lymphography without the aid of vital dyes.

PMID- 4373625
TI  - Agencies' perceptions of factors affecting home care referral.

PMID- 4373626
TI  - [Stimulation of Australia antigen production].

PMID- 4373627
TI  - Hormones and sudden deafness.

PMID- 4373629
TI  - Electrical promontory testing in differential diagnosis of sensori-neural hearing
      impairment.

PMID- 4373628
TI  - Glomus tumors: diagnosis and treatment.

PMID- 4373630
TI  - Juvenile angiofibroma: a more rational therapeutic approach based upon clinical
      and experimental evidence.

PMID- 4373631
TI  - [Retrosternal lymphography (author's transl)].

PMID- 4373632
TI  - [Pathogenesis of ascites formation in liver cirrhosis (author's transl)].

PMID- 4373634
TI  - [Neurogenic factors and hypertension].

PMID- 4373633
TI  - The prostaglandins: their significance in clinical practice.

PMID- 4373635
TI  - Radioimmunoassay of polypeptide hormones and enzymes.

PMID- 4373636
TI  - The use of subzero temperatures in biochemistry: slow reactions.

PMID- 4373637
TI  - Newer developments in the determination of cyclic AMP and other cyclic
      nucleotides, adenylate cyclase, and phosphodiesterase.

PMID- 4373638
TI  - In vitro study of the influence of some factors important for any physicochemical
      characterization of loose connective tissue in the microcirculation.

PMID- 4373640
TI  - Electron microscopic studies on various types of inclusions found in autopsy
      cases. PART 111. Observation on fine structure of cytomegalovirus in paraffin
      embedded tissue.

PMID- 4373639
TI  - Peripheral neuropathy.

PMID- 4373641
TI  - [Atypical case of insulinoma (author's transl)].

PMID- 4373642
TI  - [Letter: Effect of diuretics in diabetes insipidus].

PMID- 4373643
TI  - [Therapy of gas gangrene. Comparison of results of the standard and hyperbaric
      oxygen therapy (author's transl)].

PMID- 4373644
TI  - [Therapy of cyanide poisoning using 4-dimethylaminophenol (4-DMAP). Report on a
      case of poisoning in man].

PMID- 4373645
TI  - [On the fetopathy caused by the cytomegalic virus].

PMID- 4373646
TI  - Physiology and genetics of carbamoylphosphate synthesis in Escherichia coli K12.

PMID- 4373647
TI  - Models of the quaternary structure of collagenase.

PMID- 4373648
TI  - Kinetic scheme and kinetic parameters of the exchange of ATP-32P-pyrophosphates,
      catalyzed by tryptophanyl-tRNA synthetase from beef pancreas.

PMID- 4373649
TI  - Amino acid esters of 2'-O-methyladenosing -peptide acceptors in the ribosome. The
      role of 2'-hydroxyl.

PMID- 4373650
TI  - Comparative studies of host-cell reactivation, colony forming ability and
      excision repair after UV irradiation of xeroderma pigmentosum, normal human and
      some other mammalian cells.

PMID- 4373651
TI  - Chloroquine inhibition of repair of DNA damage induced in mammalian cells by
      methyl methanesulfonate.

PMID- 4373652
TI  - Detection of somatic recombination and mutation in Drosophila. A method for
      testing genetic activity of chemical compounds.

PMID- 4373653
TI  - Effect of heterologous transplantation of H 4-II-E rat hepatoma cells into the
      cheek pouch of irradiated hamster.

PMID- 4373654
TI  - Utilization of methadone hydrochloride for opiate addiction.

PMID- 4373655
TI  - An SV40-induced initiation factor for protein synthesis concerned with the
      regulation of permissiveness.

PMID- 4373656
TI  - Separation of parathyroid hormone and calcitonin-sensitive cells from non
      responsive bone cells.

PMID- 4373657
TI  - Excitatory action of hypothalamic substance P on spinal motoneurones of newborn
      rats.

PMID- 4373658
TI  - Pseudotype formation between enveloped RNA and DNA viruses.

PMID- 4373659
TI  - Effect of dexamethasone on herpes simplex virus type 2 infection in vitro.

PMID- 4373660
TI  - Increased susceptibility to virus oncogenesis of congenitally thymus-deprived
      nude mice.

PMID- 4373661
TI  - Inhibition of rat lymph node cell cytotoxicity by hepatoma-associated embryonic
      antigen.

PMID- 4373662
TI  - [Site of transplantation and morphology of chemically induced gliomas in the
      rat].

PMID- 4373663
TI  - Changes induced in rabbit plasma lipoproteins by polyunsaturated fat.

PMID- 4373664
TI  - [A patient with diabetes mellitus and Sheehan's syndrome].

PMID- 4373665
TI  - [Neuropathy in chronic renal insufficiency: significance of the study of
      conduction rate and vibration].

PMID- 4373666
TI  - [Neuropeptides and behavior].

PMID- 4373667
TI  - [New trends in human psychopharmacology].

PMID- 4373668
TI  - [The other side of the moon or the dark side of atopy].

PMID- 4373669
TI  - Establishment of continuous cell lines from leukocytes culture of a hamadryas
      baboon with leukosis-reticulosis.

PMID- 4373670
TI  - Peripheral neuropathy in chronic renal failure.

PMID- 4373671
TI  - [Case of Kinsbourne's infantile myoclonic encephalopathy].

PMID- 4373673
TI  - [Prostaglandin (author's transl)].

PMID- 4373672
TI  - [Biochemistry of brain tumor--brain tumor protein and immune reactions (author's
      transl)].

PMID- 4373674
TI  - [Endocrine, water and electrolyte abnormalities of craniopharyngioma (author's
      transl)].

PMID- 4373676
TI  - [Neurosurgical experience of the pre-and postoperative administration of
      corticosteroids in large doses; its antiedematous effects and clinical assessment
      (author's transl)].

PMID- 4373675
TI  - [Endocrinological evaluation of sellar and suprasellar tumor cases --the first
      report-- on preoperative pituitary function (author's transl)].

PMID- 4373677
TI  - [Surgical treatment for a glomus jugulare tumor--report of a case growing
      extensively (author's transl)].

PMID- 4373678
TI  - Purified ovine growth hormone releasing factor: effects on growth hormone
      secretion and pituitary cyclic nucleotide accumulation.

PMID- 4373679
TI  - Pituitary nuclear retention of dexamethasone and ACTH biosynthesis.

PMID- 4373680
TI  - Action of hemicholinium-3 on cholinergic nerve terminals after alteration of
      neuronal impulse flow.

PMID- 4373681
TI  - [A new case of object agnosia. A deficit in association or categorization
      specific for the visual modality].

PMID- 4373682
TI  - Spontaneous skin potential responses during sleep: comparative studies in
      newborns and babies between 2 and 5 months of age.

PMID- 4373683
TI  - [Insuloma: a reality not to be forgotten].

PMID- 4373684
TI  - Concurrent pulmonary tuberculosis and bronchogenic carcinoma. Experience in large
      municipal hospital.

PMID- 4373685
TI  - Letter: Hydrocyanic acid poisoning of cattle associated with sudax grass.

PMID- 4373686
TI  - Biologic behavior of primary ovarian malignancy.

PMID- 4373687
TI  - [Differential diagnosis of epidemic hemorrhagic conjunctivitis].

PMID- 4373688
TI  - Metabolic properties of mouse transplantable adenocarcinoma. III. Oxidative
      phosphorylation by tumor and normal submaxillary gland mitochondria.

PMID- 4373690
TI  - Verruciform xanthoma. A clinical, light microscopic, and electron microscopic
      study of two cases.

PMID- 4373691
TI  - Metastasis to the gingiva. Report of a case of metastasis from the breast and
      review of the literature.

PMID- 4373689
TI  - In vitro assay for human breast cancer hormone responsiveness. A study of 25
      cases with clinical correlation.

PMID- 4373692
TI  - [State of the hypothalamo-hypophyseal-adrenal system in the lethal form of
      hypoxemia].

PMID- 4373693
TI  - [Treatment of pituitary dwarfism].

PMID- 4373694
TI  - [Paraneoplastic hypercorticism. Hypokalemia, increased plasma renin activity and
      hypoaldosteronism during cancer of the pancreas].

PMID- 4373695
TI  - Enzymatic mechanisms in the chemotaxis of neutrophils.

PMID- 4373696
TI  - [Comparative quantitative scintigraphic studies with 99mTc pyrophosphate and 85Sr
      in pathologic bone transformation].

PMID- 4373697
TI  - A comparison of the bone seeking properties of short-chained 99mTc-Sn
      polyphosphates.

PMID- 4373698
TI  - [Kinetics of 99mTc04-accumulation in thyroid gland].

PMID- 4373699
TI  - [History of studies on the Teschen disease virus (meningoencephalomyelitis
      enzootica suum) in Poland].

PMID- 4373700
TI  - Renaturation of inactivated interferons by "defensive reversible denaturation".

PMID- 4373701
TI  - Impact of adenoviruses in human disease.

PMID- 4373703
TI  - Parainfluenza virus infections.

PMID- 4373702
TI  - Respiratory syncytial virus in infants and children.

PMID- 4373704
TI  - Sexually transmitted diseases.

PMID- 4373705
TI  - Acute viral gastroenteritis.

PMID- 4373706
TI  - Esterification of low density lipoprotein cholesterol in human fibroblasts and
      its absence in homozygous familial hypercholesterolemia.
AB  - A new mechanism is described for the cellular esterification of cholesterol
      derived from extra-cellular lipoproteins. Incubation of monolayers of cultured
      fibroblasts from normal human subjects with low density lipoproteins led to a 30-
      to 40-fold increase in the rate of incorporation of either [(14)C]acetate or
      [(14)C]oleate into the fatty acid fraction of cholesteryl [(14)C]esters. This
      stimulation of cholesteryl ester formation by low density lipoproteins occurred
      despite the fact that endogenous synthesis of free cholesterol was completely
      suppressed by the lipoprotein. Thus, exogenous cholesterol contained in low
      density lipoproteins, rather than endogenously synthesized sterol, appeared to
      provide the cholesterol substrate for this cellular esterfication process. High
      density lipoproteins and the lipoprotein-deficient fraction of serum neither
      stimulated cholesteryl ester formation nor inhibited cholesterol synthesis. Both
      the low density lipoprotein-dependent increase in cholesterol esterification and
      decrease in free cholesterol synthesis required the interaction of the
      lipoprotein with its recently described cell surface receptor. Cells from
      homozygotes with familial hypercholesterolemia, which lack specific low density
      lipoprotein receptors, showed neither lipoprotein-dependent cholesterol
      esterification nor suppression of cholesterol synthesis. The reciprocal changes
      in free cholesterol synthesis and cholesteryl ester formation produced by low
      density lipoprotein-receptor interactions may play an important role in the
      regulation of the cholesterol content of mammalian cells.

PMID- 4373707
TI  - Proton magnetic resonance spectra of Rhodospirillum rubrum cytochrome c2.
AB  - Nuclear magnetic resonance spectra of ferro- and ferricytochrome C(2) from the
      facultative photoheterotroph, Rhodospirillum rubrum, obtained with a 220-MHz
      spectrometer, are presented. Assignments to protons of various important
      structural groups in contact with or near the prosthetic heme group are given.
      These include (a) in the ferro-form, methyl, cbeta and cgamma protons of the
      extraplanar ligand residue, methionine 91, and methyl protons of the residue
      leucine 32; and (b) corresponding protons in the ferri-form with the addition of
      methyl protons from the condensation of a heme vinyl group with cysteine 17, a
      single proton from the condensation involving cysteine 14, and protons from the
      ring methyls. These resonances are compared with those corresponding to the same
      groups in horse heart cytochrome c.

PMID- 4373708
TI  - Differential lectin agglutination of fetal, dividing-postnatal, and malignant
      hepatocytes.
AB  - Numerous studies have reported the capacity of the lectin, concanavalin A, to
      agglutinate selected cell-types. The finding that cells transformed in culture,
      embryonic cells, and malignant cells are all agglutinated by this substance, may
      contribute to our understanding of the oncogenic process. The present study
      compared the response to concanavalin A of rat hepatocytes derived from livers of
      differing developmental and mitotic-status as well as those derived from
      malignant liver tumors (hepatomas). Fetal hepatocytes and hepatoma cells were
      highly susceptible to agglutination while hepatocytes from post-natal livers,
      whether dividing or quiescent, were not. Treatment with protease(s) did not make
      the interphase hepatocyte agglutinable. These data emphasize the importance of
      examining a wide variety of cells in attempting to understand the interaction of
      lectins on cell surfaces, and further, demonstrate the value of obtaining cells
      directly from tissue(s) during differing physiologic and pathologic states.

PMID- 4373709
TI  - Evolution of type C viral genes: I. Nucleic acid from baboon type C virus as a
      measure of divergence among primate species.
AB  - Hybridization studies with a [(3)H]DNA probe from an endogenous baboon type C
      virus were used to detect nucleic acid sequences of type C virus in primate
      cellular DNA. Sequences related to those of the baboon type C virus are found in
      all other Old World monkey species, higher apes, and man.

PMID- 4373710
TI  - Regulation of herpesvirus macromolecular synthesis: nuclear retention of
      nontranslated viral RNA sequences.
AB  - We report two instances of selective accumulation of herpes simplex 1 RNA
      transcripts in different compartments of infected HEp-2 cells. In the first,
      transcripts derived from about 50% of the viral DNA accumulated in the nuclei of
      cells 8 hr after infection. However, only 40-42% of the DNA was represented in
      transcripts accumulating in both cytoplasm and polyribosomes. A more striking
      disparity in the distribution of transcripts between nuclei and cytoplasm
      occurred when viral infection was initiated and maintained for several hours in
      the absence of protein synthesis. RNA complementary to about 50% of the viral DNA
      accumulated in the nuclei, while transcripts derived from only about 10% of the
      DNA were detectable in the cytoplasm. The transcripts that were selectively
      transported in the presence of cycloheximide seem to be functional messenger RNA
      molecules, since they were found on polysomes immediately after cycloheximide
      reversal. In contrast, RNA retained in the nuclei during the period of
      cycloheximide treatment was not mobilized when protein synthesis subsequently
      resumed. The two instances of selective RNA transport observed during herpesvirus
      infection suggest that only viral transcripts competent to function in
      translation are exported from the nucleus.

PMID- 4373711
TI  - Characterization of binding components for progesterone and 5alpha-pregnane-3,20
      dione in the hamster uterus.
AB  - In the hamster uterus, a specific progesterone (pregn-4-ene-3,20-dione) receptor
      has been identified in the cytosol fraction. In the present study, we examined
      hamster uterine cytosol for the possible existence of specific macromolecules
      that bind the progesterone metabolite, 5alpha-pregnane-3,20-dione. When cytosol
      was analyzed by density-gradient centrifugation with sucrose-glycerol gradients
      and by Scatchard plot analysis of [(3)H]5alpha-pregnane-3,20-dione binding data,
      there was no evidence of specific binding components for this metabolite. In vivo
      treatment of proestrous hamsters with unlabeled progesterone, 5alpha-pregnane
      3,20-dione, or cortisol for 1 hr revealed that only progesterone caused the
      depletion of progesterone-receptor sites from the uterine cytosol fraction.
      Incubation of uterine strips which had been preloaded with two different
      concentrations of [(3)H]-progesterone demonstrated that progesterone was
      metabolized to 5alpha-pregnane-3,20-dione and to a greater extent to 3alpha
      hydroxy-5alpha-pregnan-20-one. The accumulation of 5alpha-pregnane-3,20-dione
      during progesterone metabolism appeared to be related to the availability of
      nonspecifically bound hormone. These studies (i) strongly suggest there is no
      specific receptor system for 5alpha-pregnane-3,20-dione in the uterine cytosol
      fraction, (ii) confirm the existence of a specific progesterone receptor in
      uterine cytosol, and (iii) provide evidence that progesterone itself mediates the
      uterine progestational response via interaction with a specific receptor system.

PMID- 4373713
TI  - Characterization of the end groups of RNA of Rous sarcoma virus.
AB  - The 3' terminus of the 30-35S RNA of Rous sarcoma virus is adenosine. Its amount
      indicates an average molecular weight for that RNA of about 3 x 10(6). The 5'
      terminus of 30-35S RNA of Rous sarcoma virus was not di- or triphosphorylated,
      whether isolated by the standard procedure or from virus collected within 3 min
      of its release from the cells.

PMID- 4373712
TI  - Polyriboadenylate sequences at the 3'-termini of ribonucleic acid obtained from
      mammalian leukemia and sarcoma viruses.
AB  - The location of poly(A) sequences in the RNA of mammalian RNA-tumor viruses was
      determined by enzymatic analyses. The 56-64S viral genomic RNAs, the 20-40S viral
      subunit RNAs, and the 4-5S poly(A) sequences excised from these viral RNAs were
      subjected to either hydrolysis with a 3'-OH specific exoribonuclease from Ehrlich
      ascites tumor cells or phosphorolysis from the 3'-termini with polynucleotide
      phosphorylase from Micrococcus luteus. Purified adenosine-labeled poly(A)
      fragments, excised from genomic viral RNAs by RNase A and T(1) digestion, were
      hydrolyzed with the 3'-OH specific exoribonuclease for various periods of time.
      Poly(U) filter binding studies of the residual poly(A) indicated that 97% of the
      poly(A) fragments were hydrolyzed. Adenosine-labeled genomic and subunit viral
      RNAs and excised poly(A) fragments were phosphorolyzed from their 3'-termini for
      various periods of time with polynucleotide phosphorylase. The degree of
      phosphorolysis was monitored by poly(U) filter binding studies, and CCl(3)COOH
      insolubility and solubility determinations. There was an initial preferential
      rate of phosphorolysis of the poly(A) sequences of genomic and subunit viral RNAs
      as compared to the total adenosine-labeled viral RNAs. The data from these two
      different enzymatic mechanisms of action indicated conclusively that the poly(A)
      sequences were located at the 3'-termini of genomic and subunit viral RNAs.

PMID- 4373714
TI  - Physical and physiological evidence for two phase transitions in cytoplasmic
      membranes of animal cells.
AB  - Electron spin resonance analysis of suspensions of animal cell plasma membranes
      consistently reveals four characteristic temperatures for lateral phase
      separations in the membrane lipids. Similar analysis of an aqueous dispersion of
      lipids extracted from these membranes reveals only two characteristic
      temperatures, indicating that some aspect of lipid organization in membranes is
      destroyed by the extraction procedure. The characteristic temperatures for
      surface membranes from two different species of homeothermic animals were nearly
      identical and were approximately 37 degrees , 31 degrees , 21 degrees , and 15
      degrees . A treatment of the physical data revealed that these temperatures could
      identify independent phase transitions for two hydrocarbon compartments of
      approximately equal size with lower and upper characteristic temperatures of 21
      degrees and 37 degrees , and of 15 degrees and 31 degrees . The analysis of the
      effects of temperature on a number of physiological parameters indicates that 21
      degrees and 37 degrees are likely to define the boundaries for lateral phase
      separations in the inner monolayer and 15 degrees and 31 degrees the boundaries
      for lateral phase separations in the outer monolayer.

PMID- 4373715
TI  - Nuclear coupling of 33S and the nature of free radicals in irradiated crystals of
      cystine dihydrochloride: Part II, charged radicals.
AB  - The (33)S hyperfine structure has been observed in negatively charged cystine
      molecule-radicals RCH(2)(SS)(-)CH(2)R. The coupling, found to be axially
      symmetric about the SS bond, proved the orbital of the unpaired electron to be an
      antibonding SS sigma(*) orbital with the spin density shared equally between
      3p(sigma(*)) orbitals of the two sulfurs. The (33)S hyperfine structure could not
      be detected for a second radical produced by irradiation of the cystine
      hydrochloride crystal at 77 degrees K, but interpretation of the proton hyperfine
      structure and g tensor observed by others led to the conclusion that this radical
      is the positively charged cystine molecule RCH(2)S(+)SCH(2)R with the spin
      density concentrated in a 3p orbital of one S and perpendicular to the SS bond.

PMID- 4373716
TI  - Gap junction formation between reaggregated Novikoff hepatoma cells.
AB  - We have combined freeze-fracture and electrophysiological methods in a study of
      gap junction formation between reaggregated Novikoff hepatoma cells. Cell clumps
      are dissociated with EDTA, and the resulting single cells are allowed to
      reaggregate (5-180 min) in loose pellets in the presence of calcium at 37 degrees
      . The earliest electron microscopic evidence for the genesis of new junctions is
      the appearance of flattened regions of the plasma membrane with a relative
      paucity of small intramembranous particles. These regions contain instead loosely
      organized groupings of 9- to 11-nm intramembranous particles, which are seen on
      the A face of the fractured plasma membrane, while corresponding pits occur on
      the membrane B face. We have termed the specialized membrane regions "formation
      plaques." They are seen as early as 5 min after reaggregation and are quite
      numerous by 30 min. Larger plaques are observed at later times. Plaques seen at
      30 min are consistently matched with other plaques on apposed cells, although the
      extracellular space separating these structures still exceeds 10 nm. By 60 min,
      some matched plaques display a reduced extracellular space, resembling that of
      normal gap junctions. Between 30 and 60 min, aggregates of closely packed
      particles on A faces and hexagonally arranged pits on B faces frequently appear
      in the formation plaques. The aggregates, which are indistinguishable from small
      gap junctions, appear to enlarge over the subsequent 2-hr period as the number of
      unaggregated 9- to 11-nm particles declines. Microelectrode studies demonstrate
      progressive increases in the percent of interfaces containing lowresistance
      junctions and in the degree of elctrical coupling in preparations incubated up to
      2 hr. Coupling is first detected at about the same time as particle aggregates
      (or formation plaques with reduced extracellular spaces), and increases as
      aggregate sizes increase.

PMID- 4373717
TI  - Structure and molecular weight of the 60-70S RNA and the 30-40S RNA of the Rous
      sarcoma virus.
AB  - The structure and molecular weight of the 60-70S RNA complex and the 30-40S RNA
      species of Rous sarcoma virus were analyzed in an electron microscope after
      treatment of the RNAs with the bacteriophage T4 gene-32 protein to stretch out
      the RNA strands. Although all RNA preparations treated with gene-32 protein
      showed considerable heterogeneity in length, a significant fraction of the RNA
      retained its original sedimentation coefficient after treatment to allow the
      following conclusions to be made: The 30-40S RNA was confirmed to be a linear
      polynucleotide with a molecular weight of about 3 x 10(6). The 60-70S RNA
      exhibited a network structure with a molecular weight predominantly of about 6 x
      10(6). Therefore, the subunit hypothesis for the 60-70S RNA is confirmed. A model
      for the structure and molecular weight of the 60-70S RNA postulates that the
      complex consists of two 30-40S RNA subunits held together at many points. This
      model elucidates the biological observation that the infectivity of RNA tumor
      viruses is proportional to the amount of 30-40S RNA in a virus preparation and
      not to the amount of 60-70S RNA.

PMID- 4373718
TI  - Intramolecular hydrogen bonding in flavin adenine dinucleotide.
AB  - Data obtained by means of proton magnetic resonance spectroscopy indicate that
      specific association of FMN occurs with AMP in aqueous solution, because much
      weaker interaction is observed with FMN of either GMP or CMP. A comparison of FAD
      with a 1:1 mixture of FMN and AMP suggests that the flavin is involved in an
      intramolecular hydrogen bonding with the adenine moiety of FAD. The temperature
      dependence of chemical shifts would seem to indicate that the pyrophosphate
      linkage acts to reinforce stacking interactions as well as hydrogen bonding in
      the coenzyme. The linkage also limits the number of cyclic hydrogen bonding
      configurations, and a model is proposed to describe a fraction of unstacked FAD
      in aqueous solution.A parallel study was made of NAD(+) and its analogues; in
      contrast to FAD, no clear evidence of cyclic hydrogen bonding was obtained with
      the pyridine coenzymes.

PMID- 4373719
TI  - Purification and properties of rat liver microsomal stearyl coenzyme A
      desaturase.
AB  - The terminal enzyme of the NADH-dependent stearyl coenzyme A desaturase system
      has been isolated from rat liver microsomes. This desaturase is a single
      polypeptide of 53,000 daltons containing 62% nonpolar amino-acid residues and one
      atom of non-heme iron. The purified protein forms high molecular weight
      aggregates that can be dispersed by detergent procedures. Desaturase activity
      requires NADH, stearyl coenzyme A, oxygen, lipid, and the three enzymes,
      cytochorme b(5) reductase (EC 1.6.2.2), cytochrome b(5), and desaturase.
      Cytochrome b(5) is the direct electron donor to the desaturase, which appears to
      utilize the iron in the oxidation-reduction sequence during desaturation of
      stearyl coenzyme A.

PMID- 4373720
TI  - Behavior of three types of ribovirus-like particles in segregating hamster times
      mouse somatic hybrids.
AB  - An electron microscopic study of somatic hybrids resulting from a cross between
      hamster melanoma cells harboring R-type particles and mouse fibroblasts harboring
      intracisternal A-type and (mostly) immature C-type particles was performed. The
      major findings are: (a) hybrid cells that retain a large fraction of both hamster
      and mouse chromosomes produce all three types of particles; (b) the loss of mouse
      chromosomes is followed by that of intracisternal A- and C-type particles; (c)
      the continued production of A- and C-type particles is dependent on the retention
      of different mouse chromosomes; (d) the mixed intracellular population of R- and
      A-particles comprises a small number of complex structures in which the two types
      of virions are enclosed within a common envelope.

PMID- 4373721
TI  - Adenylate cyclase from Brevibacterium liquefaciens. III. In situ regulation of
      adenylate cyclase by pyruvate.
AB  - In the presence of DL-alanine intracellular cyclic AMP in nonproliferating cells
      of Brevibacterium liquefaciens increased rapidly to the maximum level of
      approximately 180 muM, and extracellular cyclic AMP increased to 100 muM within 4
      hr at 25 degrees . Adenylate cyclase (EC 4.6.1.1) induction was not observed
      during this incubation. The concentration of pyruvate in the total culture
      increased concomitantly with that of cyclic AMP and reached approximately 20 mM
      after 4 hr of incubation. Since the activity of cyclic nucleotide
      phosphodiesterase is extremely low in this bacterium, the accumulation of cyclic
      AMP with DL-alanine appeared to be due to the activation of adenylate cyclase by
      pyruvate. D-alanine was more effective than L-alanine in producing pyruvate, and
      a high activity of D-alanine oxidation was detected in the cell lysate of B.
      liquefaciens.Thus, adenylate cyclase in this bacterium appeared to be regulated
      in vivo by pyruvate which was formed, in this case, predominantly from D-alanine
      through the action of D-aminoacid oxidase (EC 1.4.3.3). Pyruvate, added
      extracellularly, also caused a rapid accumulation of intracellular cyclic AMP.
      Glucose did not change the level of cyclic AMP significantly. It also did not
      affect the intracellular accumulation of cyclic AMP with DL-alanine.

PMID- 4373722
TI  - Participation of N1-oxide derivatives of adenine nucleotides in the
      phosphotransferase activity of liver mitochondria.
AB  - The modified adenine nucleotides ATP-NO, ADP-NO, and AMP-NO were tested as
      potential substrates and/or inhibitors of mitochondrial phosphotransferases. ADP
      NO is not recognized by the translocase system located in the inner mitochondrial
      membrane; however, it is rapidly phosphorylated to ATP-NO in the outer
      compartment of mitochondria, by way of the nucleosidediphosphate kinase (EC
      2.7.4.6) reaction, provided there is sufficient ATP in the mitochondria. AMP-NO
      is not phosphorylated by liver mitochondria to the corresponding nucleoside
      diphosphate; it cannot serve as substrate for adenylate kinase (EC 2.7.4.3). ATP
      NO and ADP-NO, however, are substrates of this enzyme. The apparent equilibrium
      constant for the reaction, ADP-NO + ADP right harpoon over left harpoon ATP-NO +
      AMP, of 0.908 at pH 7.4 and 5 mM Mg(2+) is significantly higher than that of the
      reaction with natural nucleotides. Although adenosine N(1)-oxide is easily
      phosphorylated to AMP-NO by adenosine kinase [Schnebli et al. (1967) J. Biol.
      Chem. 242, 1997-2004], the formation of corresponding nucleoside triphosphate in
      vivo seems also to be limited by adenylate kinase; adenosine N(1)-oxide cannot
      replace adenosine in restoring the normal ATP level in ethionine-treated rats.

PMID- 4373723
TI  - Effect of a fibroblast growth factor, insulin, dexamethasone, and serum on the
      morphology of BALB/c 3T3 cells.
AB  - The effects of serum, fibroblast growth factor, dexamethasone, and insulin on the
      morphology of two lines of BALB/c 3T3 cells are described and illustrated.
      Fibroblast growth factor, a polypeptide purified from bovine brain and pituitary
      glands, stimulates DNA synthesis and cell division in both sparse and confluent
      cultures of quiescent 3T3 cells. When cells are grown in the presence of the
      factor, they go through one or two cycles of division and their morphology
      differs from that of cells either growing in 10% serum or maintained in a
      quiescent state in low serum; they appear rounded with long processes and show no
      sign of contact inhibition. When dexamethasone is present with the growth factor,
      the cells grow to a high density and are not contact-inhibited; they have the
      appearance of transformed cells. Addition of insulin or dibutyryl cyclic AMP to
      the cells results in a morphology similar to that of cells growing in the
      presence of serum. Addition of growth factor or growth factor plus dexamethasone
      to cells that have reached confluency in 10% serum and that are clearly contact
      inhibited results in the resumption of growth. The final cell density reached is
      similar to that of cells growing in the presence of 30% serum with daily fluid
      changes. No contact inhibition is observed in either of these situations.

PMID- 4373724
TI  - Glycophorin in lipid bilayers.
AB  - Glycophorin, the major glycoprotein of human erythrocytes, has been isolated and
      reincorporated into lipid vesicles. Freeze-fracture electron microscopy shows the
      reincorporated glycophorin to occur as small particles in vesicle fracture faces
      while the etch faces are smooth. The glycoprotein has a tendency to cluster into
      groups of several particles. Evidence is presented that, although lipids in
      immediate contact with glycopherin are likely somewhat immobilized, the entire
      lipid-protein complex has a tendency to occupy fluid regions of the bilayer.
      Reincorporated glycophorin assumes its proposed conformation in the intact
      erythrocyte in so far as it penetrates the hydrophobic membrane interior while
      its N-terminal end with attached carbohydrate residues is exposed to the aqueous
      compartment and is available as a specific recognition site.

PMID- 4373725
TI  - Latent DNA of Epstein-Barr virus: separation from high-molecular-weight cell DNA
      in a neutral glycerol gradient.
AB  - Epstein-Barr virus DNA in virus non-productive cells was separated from high
      molecular-weight cell DNA by sedimentation through a neutral glycerol gradient
      after gentle lysis of cells by Pronase and Sarkosyl. The isolated Epstein-Barr
      virus DNA had a density of 1.716-1.717 g/cm(3) in CsCl equilibrium
      centrifugation, which is very close to the virus DNA density of 1.718 g/cm(3).
      The results indicated that the majority of Epstein-Barr virus DNA in virus
      nonproductive cells is not covalently integrated into high-molecular-weight cell
      DNA.

PMID- 4373726
TI  - Coexistence of several putative neurotransmitters in single identified neurons of
      Aplysia.
AB  - By sensitive enzymatic micromethods several putative neurotransmitters were
      measured in four identifiable neurons of Aplysia californica (R-2, R-14, L-11,
      and C-1). Serotonin was found in all of these neurons, and octopamine in all but
      C-1. Acetylcholine has been previously reported to be present in R-2 and L-11.
      The catecholamines, norepinephrine and dopamine, were not detected in the four
      cells examined. The possible biological consequence of the presence of several
      putative transmitters in single identifiable neurons is discussed.

PMID- 4373727
TI  - Competitive inhibition of beef heart cyclic AMP phosphodiesterase by cytokinins
      and related compounds.
AB  - Two cytokinins and four related analogs, none of which is a cyclic
      ribonucleotide, have been shown to act as competitive inhibitors of the high K(m)
      cyclic-AMP phosphodiesterase (3':5'-cyclic-AMP 5'-nucleotidohydrolase, EC
      3.1.4.17) activity from beef heart. Weak inhibition of the low K(m) cyclic AMP
      phosphodiesterase activity was also observed, suggesting a possible mechanism for
      regulation of intracellular cyclic AMP levels by the exogenously added compounds.
      In addition to the kinetic data, obtained on the six inhibitors in four different
      heterocyclic series, 15 other cytokinins and related compounds have been shown to
      inhibit the high K(m) cyclic AMP phosphodiesterase activity at single
      concentrations of substrate and inhibitor. Heterocycles such as adenosine and 7
      amino-3-methylpyrazolo[4,3-d]pyrimidine, which lack the N-substituent, were
      inactive as cyclic AMP phosphodiesterase inhibitors. The observed inhibition of
      cyclic AMP phophodiesterase supports prior observations which implicate
      exogenously added cytokinins in cyclic AMP metabolism.

PMID- 4373728
TI  - Direct evidence for the presence of Epstein-Barr virus DNA and nuclear antigen in
      malignant epithelial cells from patients with poorly differentiated carcinoma of
      the nasopharynx.
AB  - A well-differentiated squamous cell carcinoma and three poorly differentiated
      carcinomas of the nasopharynx were analyzed for the presence of Epstein-Barr
      virus DNA by hybridization with radioactive complementary RNA. The well
      differentiated carcinoma contained no detectable Epstein-Barr virus DNA, whereas
      the three anaplastic carcinomas contained 41, 16, and 14 viral genome equivalents
      per cell. The anaplastic carcinomas were heavily infiltrated with lymphocytes and
      other non-neoplastic cells. All four tumors were successfully passaged in nude
      (thymusless) mice. Mouse cell admixture in the heterotransplanted tumors was
      estimated by analysis of glucose-6-phosphate dehydrogenase (EC 1.1.1.49) and
      varied between 25% and 80%. After two passages in nude mice, the carcinoma that
      was negative for Epstein-Barr virus DNA remained negative, while the three
      anaplastic carcinomas retained their viral DNA. After correction for mouse cell
      admixture, the latter tumors were found to contain about 80, 55, and 160 Epstein
      Barr virus genome equivalents per human cell. The virus-determined nuclear
      antigen was localized in the large carcinoma cell clusters in all three mouse
      passaged tumors positive for the viral DNA, but other virus-determined antigens
      were not detected, indicating the absence of virus induction. In contrast to the
      original tumor biopsies, the nude-mouse-passaged tumors showed virtually no
      lymphocytic infiltration. It is concluded that the Epstein-Barr virus DNA found
      in biopsies of human nasopharyngeal carcinomas is localized in the neoplastic
      cells.

PMID- 4373729
TI  - Isolation of a viral polypeptide associated with poliovirus RNA polymerase.
AB  - Poliovirus-infected HeLa cells were labeled with radioactive methionine or
      phenylalanine and subjected to a new purification procedure for the viral induced
      RNA polymerase activity. Detergent-solubilized polymerase activity was purified
      by precipitation with 2 M LiCl and sedimentation through sucrose gradients.
      Approximately 0.001% of the incorporated amino acid radio-activity sediments with
      the peak of polymerase activity. Gradient fractions comprising the polymerase
      activity peak were analyzed by sodium dodecyl sulfate-polyacrylamide gel
      electrophoresis and found to contain predominantly one virus-specific
      polypeptide. Polyacrylamide gel electrophoresis also reveals that this purified
      polypeptide migrates with a 58,000 molecular weight noncapsid polio-virus
      polypeptide.

PMID- 4373730
TI  - Plasminogen activator production accompanies loss of anchorage regulation in
      transformation of primary rat embryo cells by simian virus 40.
AB  - We have isolated several lines of rat embryo cells transformed by simian virus
      40. All these lines are fully transformed with regard to saturation density and
      serum sensitivity, but they differ greatly in their anchorage dependence, as
      assayed by efficiency of plating in methyl cellulose suspension. This set of
      lines reveals a consistent relation of plasminogen activator production to
      plating efficiency in methyl cellulose. T-antigen-positive transformed lines that
      synthesize activator grow in methyl cellulose suspension, while T-antigen
      positive transformed lines that do not synthesize activator fail to form colonies
      in suspension. Normal rat embryo cells produce very little plasminogen activator
      and do not grow in methyl cellulose. Sera that permit high levels of plasmin
      formation and activity support growth in semi-solid medium better than sera whose
      plasminogen is activated poorly and/or sera that contain inhibitors to plasmin.

PMID- 4373731
TI  - Focal erythrocyte membrane perturbations caused by nitroxide lipid analogues.
AB  - Three classes of lipoidal nitroxide spin probes reversibly perturb erythrocyte
      membranes at low concentrations (10(-10)-10(-5) M). This is manifest in (a)
      decreased osmotic fragility and (b) alterations of surface topology. At bulk
      phase nitroxide concentrations providing maximal osmotic stabilization, the
      erythrocytes exhibit a classic echinocyte morphology. At nitroxide concentrations
      very slightly higher than those yielding minimal osmotic fragility (10(-5)-10(-4)
      M), the cellus undergo a sphering reaction and lyse. The morphologic sequence
      seen in intact cells is not observed in erythrocyte ghosts. We suggest that the
      spin probes initially concentrate in focal domains, which expand into echinocytic
      protrusions primarily due to localized weakening of membrane cohesion. We propose
      that cell lysis involves an irreversible breakdown in membrane domain structure.

PMID- 4373732
TI  - Viable deletion mutants of simian virus 40: selective isolation by means of a
      restriction endonuclease from Hemophilus parainfluenzae.
AB  - Resistance of simian virus 40 (SV40) DNA to cleavage by Hemophilus parainfluenzae
      II (HpaII) restriction endonuclease has been used as a positive, in vitro
      selection for mutants lacking the one HpaII endonuclease-cleavage site of wild
      type SV40 DNA. Each of 10 viable mutants isolated by this procedure multiplies
      significantly more slowly than wild-type virus and contains a small deletion (80
      to 190 base pairs in size) of the region of the genome that includes the HpaII
      endonuclease-recognition sequence. These well-defined mutants, having a selective
      disadvantage for growth, would not have been readily obtained by conventional
      methods used to screen for viral mutants. Therefore, in certain circumstances,
      restriction endonucleases are effective reagents for the selection of new classes
      of mutants. Because these small deletions can be visualized in heteroduplexes,
      these mutants provide internal markers for mapping other alterations or features
      of the simian virus 40 genome.

PMID- 4373733
TI  - Initiator RNA in discontinuous polyoma DNA synthesis.
AB  - During replication of polyoma DNA in isolated nuclei, RNA was found attached to
      the 5' ends of growing progeny strands. This RNA starts with either ATP or GTP
      and can be labeled at its 5' end with (32)P from beta-labeled nucleotides.
      Digestion of progeny strands with pancreatic DNase released (32)P-labeled RNA
      that, on gel electrophoresis, gave a distinct peak in the position expected for a
      decanucleotide. We believe that this short RNA is involved in the initiation of
      the discontinuous synthesis of DNA and propose the name "initiator RNA" for it.
      The covalent linkage of initiator RNA to 5' ends of growing DNA chains was
      substantiated by the finding that (32)P was transferred to ribonucleotides by
      alkaline hydrolysis of purified initiator RNA obtained by DNase digestion of
      polyoma progeny strands synthesized from [alpha-(32)P]dTTP. While initiator RNA
      was quite homogeneous in size, it had no unique base sequence since digestion
      with pancreatic RNase of initiator RNA labeled at its 5' end with (32)P released
      a variety of different [(32)P]oligonucleotides. The switch from RNA to DNA
      synthesis during strand elongation may thus depend on the size of initiator RNA
      rather than on a specific base sequence.

PMID- 4373734
TI  - Kirromycin, an inhibitor of protein biosynthesis that acts on elongation factor
      Tu.
AB  - Kirromycin, a new inhibitor of protein synthesis, is shown to interfere with the
      peptide transfer reaction by acting on elongation factor Tu (EF-Tu). All the
      reactions associated with this elongation factor are affected. Formation of the
      EF-Tu.GTP complex is strongly stimulated. Peptide bond formation is prevented
      only when Phe-tRNA(Phe) is bound enzymatically to ribosomes, presumably because
      GTP hydrolysis associated with enzymatic binding of Phe-tRNA(Phe) is not followed
      by release of EF-Tu.GDP from the ribosome. This antibiotic also enables EF-Tu to
      catalyze the binding of Phe-tRNA(Phe) to the poly(U).ribosome complex even in the
      absence of GTP. EF-Tu activity in the GTPase reaction is dramatically affected by
      kirromycin: GTP hydrolysis, which normally requires ribosomes and aminoacyl-tRNA,
      takes place with the elongation factor alone. This GTPase shows the same K(m) for
      GTP as the one dependent on Phe-tRNA(Phe) and ribosomes in the absence of the
      antibiotic. Ribosomes and Phe-tRNA(Phe), but not tRNA(Phe) or Ac-Phe-tRNA(Phe),
      stimulate the kirromycin-induced EF-Tu GTPase. These results indicate that the
      catalytic center of EF-Tu GTPase that is dependent upon aminoacyl-tRNA and
      ribosomes is primarily located on the elongation factor. In conclusion,
      kirromycin can substitute for GTP, aminoacyl-tRNA, or ribosomes in various
      reactions involving EF-Tu, apparently by affecting the allosteric controls
      between the sites on the EF-Tu molecule interacting with these components.

PMID- 4373735
TI  - Cyclic nucleotides and growth control in cultured mouse cells: correlation of
      changes in intracellular 3':5' cGMP concentration with a specific phase of the
      cell cycle.
AB  - The commencement of cell growth following serum addition to quiescent cultures of
      mouse fibroblasts is preceded by transient changes in intracellular
      concentrations of cAMP and cGMP. By artificial depletion of the culture medium
      for different nutrients, cell growth can be reversibly arrested in various phases
      of the cell cycle. Here it is shown that the major cGMP increases are only
      observed when cultures which are arrested in the G(0) phase are stimulated to
      grow or when synchronized growing cells pass through the G(1) phase. In addition
      to its concomitant decrease, cAMP exhibits rhythmic changes during the cell
      cycle. This suggests that the increase in cGMP could act as a specific signal for
      movement of cells out of the G(0) or G(1) phase of the cell cycle by activating
      the pleiotypic and mitogenic program of the cell.

PMID- 4373736
TI  - Demonstration of a genetic factor influencing spontaneous release of a xenotropic
      virus of mouse cells.
AB  - There is increasing evidence that mouse cells of different strains contain
      different numbers and biologic classes of naturally-integrated type-C RNA
      viruses. The present studies have examined the cellular regulation of one class
      of virus, xenotropic in host range, which is common to mice of NIH Swiss and NZB
      strains. This virus is spontaneously released at high level by NZB embryo cells
      but its production by NIH Swiss embryo cells is below detectable levels.
      Quantitative analysis of the chronic level of virus release by embryo cell lines
      established in tissue culture from genetic crosses of NIH and NZB strains has
      demonstrated the existence of a partially dominant gene influencing virus
      release. Evidence is presented indicating that this gene may act to provide a
      factor necessary for expression of a specific class of endogenous virus.

PMID- 4373737
TI  - Unscheduled DNA synthesis in the germ cells of male mice exposed in vivo to the
      chemical mutagen ethyl methanesulfonate.
AB  - An unscheduled DNA synthesis has been clearly demonstrated in meiotic and
      postmeiotic germ cell stages of the male mouse after in vivo treatment with a 250
      mg/kg dose of ethyl methanesulfonate. The germ cell stages showing unscheduled
      DNA synthesis range from early to middle meiotic prophase stages through early to
      middle spermatid stages. The initiation of this synthesis, taken to be repair of
      chemically damaged DNA in these germ cells, is rapid, beginning within 1 hour
      after the injection of ethyl methanesulfonate. Unscheduled DNA synthesis has not
      been detected in the most mature germ cell stages, which give rise to dominant
      lethal mutations, nor does it occur in germ cell stages where protamine has
      replaced the chromosomal histones.

PMID- 4373738
TI  - A quantal analysis of the synaptic depression underlying habituation of the gill
      withdrawal reflex in Aplysia.
AB  - Habituation, one of the simplest behavioral paradigms for studying memory, has
      recently been examined on the cellular level in the gill-withdrawal reflex in the
      mollusc Aplysia and in the escape response in cray-fish. In both cases short-term
      habituation involved a decrease in excitatory synaptic transmission at the
      synapses between the sensory neurons and their central target cells. To analyze
      the mechanisms of the synaptic depression in Aplysia, we applied a quantal
      analysis to synaptic transmission between the sensory and motor neurons of the
      gill-withdrawal reflex. Our results indicate that short-term habituation results
      from a presynaptic mechanism: a decrease in the number of transmitter quanta
      released per impulse. The sensitivity of the postsynaptic receptor remains
      unaltered.

PMID- 4373739
TI  - Expression of murine leukemia virus structural antigens on the surface of
      chemically induced murine sarcomas.
AB  - Cultured cells of different chemically-induced C57BL/6N murine sarcomas produced
      variable amounts of infectious murine leukemia virus (MuLV) and contained
      proportional amounts of MuLV structural components as determined by
      radioimmunoassay. Monospecific antisera directed against the major MuLV
      glycoprotein (gp71), the major internal antigen (p30), and the ribonucleoprotein
      (p10) were capable of mediating tumor cell lysis in the presence of complement,
      suggesting that these viral structural components were localized at least in part
      to the cell surface. Membrane immunofluorescence studies with MuLV p30 antiserum
      confirmed surface localization. Addition of MuLV p30 polypeptide to normal cells
      and tumor cells enhanced the cytotoxicity of MuLV p30 antiserum. Studies are
      presented which suggest that the presence of MuLV structural components on cell
      surfaces can be independent of virus production and cellular transformation.

PMID- 4373740
TI  - Active transport of calcium in inverted membrane vesicles of Escherichia coli.
AB  - Accumulation of (45)Ca(++) was found to occur in membrane vesicles of E. coli
      prepared by lysis with a French pressure cell. The uptake occurs by active
      transport, requiring an energy source. Substrates of the electron transport
      chain, including D-lactate, reduced phenazine methosulfate, and NADH, stimulated
      accumulation, but this effect was blocked by the addition of cyanide. ATP could
      also stimulate accumulation, and this effect was blocked by
      dicyclohexylcarbodiimide. Uncouplers of oxidative phosphorylation inhibited the
      accumulation driven by either type of energy source. Accumulation of calcium is
      rapid, reaching the steady-state plateau within 1 min. Addition of phosphate to
      the assay buffer results in a prolongation of the reaction, allowing for the time
      dependent accumulation of calcium for as long as 30 min. Vesicles prepared by
      lysis with a French pressure cell exhibit almost no ability to accumulate
      proline, while vesicles prepared by the method of Kaback transport proline but
      exhibit little energy-dependent transport of calcium. It is suggested that the
      accumulation of calcium in these vesicles, which are believed to be inverted,
      reflects a system that in vivo is responsible for the active extrusion of calcium
      from the cells.

PMID- 4373741
TI  - Neurosurgical aspects of recurrent meningitis.

PMID- 4373742
TI  - Prudence in orthopedic surgery.

PMID- 4373743
TI  - Some new developments in the field of immunotherapy.

PMID- 4373744
TI  - Practical approach to endocrine problems in office practice.

PMID- 4373745
TI  - Effect of acute cardiac overload on intramyocardial cyclic 3',5'-AMP: relation to
      prostaglandin synthesis.

PMID- 4373746
TI  - Encephalomyocarditis (EMC) virus infection of the femoral artery of newborn mice.

PMID- 4373747
TI  - Studies on the characterization of pure submaxillary gland renin.

PMID- 4373748
TI  - Effect of dibutyryl cyclic AMP and serum deprivation on the membranes of
      transformed mouse fibroblasts. A freeze fracture study.

PMID- 4373749
TI  - Different sensitivities of type 1 and type 2 Herpes simplex virus to sodium p
      chloromercuribenzoate and chlorhexidine gluconate.

PMID- 4373750
TI  - Intranuclear binding of hydrocortisone in liver and thymus tissues.

PMID- 4373751
TI  - The effect of chronic alveolar hypoxia on lung and serum angiotensin I converting
      enzyme activity.

PMID- 4373752
TI  - Mode of action and biological properties of insoluble interferon.

PMID- 4373753
TI  - Differential effects of two strains of BCG on transplantation immunity to SV40
      induced tumors in hamsters.

PMID- 4373754
TI  - Evidence for chronic viral infections in human arteries.

PMID- 4373755
TI  - Parathyroid hormone activation of adenylate cyclase in liver.

PMID- 4373756
TI  - The role of the renin--angiotensin system in experimental renal hypertension in
      dogs.

PMID- 4373757
TI  - Effects of ions on adrenocorticotropin-sensitive adenylate cyclase of rat
      adrenals.

PMID- 4373758
TI  - Isolation and characterization of an echovirus, possible "prime" strain of
      echovirus type 12.

PMID- 4373759
TI  - Quantitative study on leucine incorporation in multinucleate cells induced by
      Sendai virus.

PMID- 4373760
TI  - Neonatal hyperthyroidism and maturation of the rat hypothalamo-hypophyseal
      adrenal axis.

PMID- 4373761
TI  - Rhinoviruses: an antigenic study of the prototype virus strains.

PMID- 4373762
TI  - Effect of phenylalanine and p-chlorophenylalanine administration on the
      development of rat brain 2',3'-cyclic nucleotide 3'-phosphohydrolase.

PMID- 4373763
TI  - Studies on the effect of collagenase and hyaluronidase on glycogen content of
      isolated rat liver parenchymal cells.

PMID- 4373764
TI  - Acute renal failure in disseminated intravascular coagulation. Experimental
      studies of the induction and prevention of renal fibrin deposition.

PMID- 4373765
TI  - Antiviral activity of selected biguanide derivatives.

PMID- 4373766
TI  - Effects of papaverine on smooth muscle and their mechanisms.

PMID- 4373767
TI  - Influence of dietary sorbitol on some enzymes linked to glucose metabolism.

PMID- 4373768
TI  - Inhibition of phosphodiesterase activity in brain cortical slices from guinea pig
      and rat.

PMID- 4373770
TI  - The effects of ACTH- and vasopressin- analogues on CO2-induced retrograde amnesia
      in rats.

PMID- 4373769
TI  - Central beta-adrenoceptor sites and ouabain action.

PMID- 4373771
TI  - [The periodicity of rem-sleep: experimental and theoretical considerations
      (author's transl)].

PMID- 4373772
TI  - The in vitro effect of different substrates and high potassium concentration on
      the respiratory rate of slices, cell suspension and homogenate of brain.

PMID- 4373775
TI  - Photosensitization of small peptides by proflavine: an E.S.R. study at low
      temperature.

PMID- 4373773
TI  - Involvement of cyclic-AMP in changes of the structuredness of cytoplasmic matrix
      (SCM).

PMID- 4373774
TI  - ESR investigations on radical formation after ultraviolet irradiation of trypsin
      in various polar and nonpolar media.

PMID- 4373776
TI  - Glomus tympanicum and glomus jugulare tumors.

PMID- 4373777
TI  - Malignant lesions of the ear.

PMID- 4373778
TI  - Oncoduction. A unifying hypothesis of viral carcinogenesis.

PMID- 4373779
TI  - Immunofluorescence antibodies in human sera to antigens in cells of a type C
      virus producing human culture of tumor origin.

PMID- 4373781
TI  - Host immune response to virus-induced tumors. Some recent concepts.

PMID- 4373780
TI  - Mechanism of cytolysis by thymus-derived lymphocytes. Implications in tumor
      immunity.

PMID- 4373783
TI  - Antigenic expression as a determining factor of tumor growth in Gross' virus
      lymphoma.

PMID- 4373782
TI  - Antigenic analysis of transformed and nontransformed cells from human neoplasms.

PMID- 4373784
TI  - Tumor-specific antigens and reexpression of fetal antigens in mammalian cells.

PMID- 4373785
TI  - Vaccine production as a unit process.

PMID- 4373786
TI  - [Virus-neutralizing antibody and mechanism of its action (author's transl)].

PMID- 4373787
TI  - [Relaxation complex of plasmid DNA (author's transl)].

PMID- 4373788
TI  - [DNA repair and genetic recombination in Bacillus subtilis (author's transl)].

PMID- 4373789
TI  - [Genetic repair system in yeast (author's transl)].

PMID- 4373791
TI  - Control of exocrine pancreas secretion in vitro: a review.

PMID- 4373790
TI  - Relative DNA contents of fibroblast nuclei after collagenase digestion.

PMID- 4373792
TI  - Carcinoma of the cervix and herpes hominis (simplex) type 2 virus infection.

PMID- 4373793
TI  - [Primary carcinoma of the liver and Australia antigen. Contribution of a case
      without liver cirrhosis].

PMID- 4373794
TI  - [Relationship angiotensine-aldosterone and respiratory function in chronic
      bronchial disease (author's transl)].

PMID- 4373795
TI  - Slow potential changes evoked in nucleus medialis dorsalis of the thalamus by
      stimulation of the amygdaloid nuclear complex.

PMID- 4373796
TI  - Uneven distribution of phospholipids in rat liver inner mitochondrial membranes.

PMID- 4373797
TI  - [Clinical and biochemical aspects of type I glycogenosis].

PMID- 4373798
TI  - Distribution of tumours in Uganda.

PMID- 4373799
TI  - Tumours of the female genitalia.

PMID- 4373800
TI  - Malignant tumours of the kidney, bladder and urethra.

PMID- 4373801
TI  - Tumours of endocrine glands.

PMID- 4373802
TI  - Tumours of bone and jaw.

PMID- 4373803
TI  - Soft tissue tumours.

PMID- 4373804
TI  - Childhood tumours.

PMID- 4373805
TI  - Metabolic effects of seizures.

PMID- 4373806
TI  - Psychiatric disturbances in endocrine disease: some issues for research.

PMID- 4373808
TI  - [Infectious embryopathies and fetopathies].

PMID- 4373807
TI  - Histamine induced changes in pulmonary guanosine-3',5'-cyclic monophosphate
      (cGMP) and adenosine-3',5'-cyclic monophosphate (cAMP) levels in mice following
      sensitization by Bordetella pertussis and/or propranolol.

PMID- 4373809
TI  - [Tumors of the endocrine cells of the pancreas (insulomas). Analysis of 15
      cases].

PMID- 4373810
TI  - [Antihypertensive drugs].

PMID- 4373811
TI  - [Abnormal secretion of renin: theoretical and practical repercussions on
      renovascular hypertension].

PMID- 4373812
TI  - [Neuro-ophthalmologic complications of ophthalmic zoster. Discussion of 126
      observations].

PMID- 4373814
TI  - [Control of the synthesis of ribonucleic acid: mechanism of hormonal regulation].

PMID- 4373813
TI  - [Action of hormones at the molecular level].

PMID- 4373815
TI  - [Preventive measures in connection with chronic on specific respiratory
      diseases].

PMID- 4373816
TI  - [Oral manifestations of eruptive infections viewing the disease in general].

PMID- 4373817
TI  - [Effect of vagotomy and pylorotomy on some histochemical reactions of main
      stomach glands in albino rats].

PMID- 4373818
TI  - [Muscular involvement in rheumatoid polyarthritis. Clinical, electromyographic,
      anatomopathological and biochemical study].

PMID- 4373819
TI  - [Mitral valve insufficiency due to ballooning of the small valve].

PMID- 4373820
TI  - [Indications for scintigraphy of the myocardium using cesium 131. Apropos of 100
      patients].

PMID- 4373821
TI  - [Bronchiolo-alveolar carcinoma and scleroderma. Report of a case and review of
      the literature].

PMID- 4373823
TI  - [Frigidity and its therapeutic approach].

PMID- 4373822
TI  - [Crohn's disease and amylosis. Apropos of a case].

PMID- 4373824
TI  - [Hypertensive episodes triggered by sulpiride].

PMID- 4373825
TI  - [IgA myeloma protein acting as an anti-stomach antibody in a gastrectomized
      patient].

PMID- 4373826
TI  - [Treatment of ectropion and benign dysplasia of the uterine cervix using
      cryotherapy].

PMID- 4373827
TI  - [Sugars and arteries. Responsibility of sugars in certain hyperlipidemias and the
      origin of atherosclerosis].

PMID- 4373828
TI  - [Recurrent benign cholestasis].

PMID- 4373829
TI  - [Psoriatic rheumatism].

PMID- 4373830
TI  - [Indications and limits of hepatic biopsy in hematology].

PMID- 4373831
TI  - [Myelofibrosis and the supporting fibrillary network of the hemopoietic bone
      marrow].

PMID- 4373832
TI  - [Myelofibrosis during hematologic diseases. Apropos of 402 cases].

PMID- 4373833
TI  - [Hypocalcemia in the child and infant].

PMID- 4373834
TI  - [Cerebral circulatory insufficiency and prevention of cerebrovascular accidents].

PMID- 4373835
TI  - [Current data on the treatment of placental tumors].

PMID- 4373836
TI  - Clostridium perfringens (Cl. welchii) in the human gastro-intestinal tract.

PMID- 4373837
TI  - Viruses associated with the healthy individual.

PMID- 4373838
TI  - The normal microbial flora of the mouth.

PMID- 4373839
TI  - The normal microbial flora of the skin.

PMID- 4373840
TI  - Range of action of the mechanism that repairs damage induced by certain chemical
      agents in Escherichia coli K-12.

PMID- 4373841
TI  - [Uremic polyneuropathy in patients treated by chronic hemodialysis].

PMID- 4373842
TI  - [Experimental studies on the etiological role of erosive silicates on the
      pathogenesis of endemic nephropathies and tumors of the urinary tract.
      Epidemiological study during the course of experimental field studies].

PMID- 4373843
TI  - Heterotransplantation of human malignant neoplasms to the mouse mutant nude.

PMID- 4373844
TI  - Alteration of cardiac contractility and hemodynamics by phosphodiesterase
      inhibition.

PMID- 4373845
TI  - Effect of portacaval shunt on hepatic Krebs-Henseleit enzymes in dogs.

PMID- 4373846
TI  - Cytomegalovirus antigen-antibody complexes in biopsy specimens in renal allograft
      rejection.

PMID- 4373848
TI  - Complete protection of severely damaged kidneys by a silica gel plasma perfusate.

PMID- 4373847
TI  - Immunosuppressive plasma factors in transplant recipients with viral infections.

PMID- 4373849
TI  - Serum albumin alterations during experimental sepsis.

PMID- 4373850
TI  - Cholera toxin as a suppressor of in vivo cell-mediated immunity.

PMID- 4373851
TI  - Morphologic evidence of direct innervation of parietal cells in rodent gastric
      mucosa.

PMID- 4373852
TI  - Calcium influx in gastric acid secretion.

PMID- 4373853
TI  - Role of cyclic AMP system in humorally stimulated gastric acid secretion.

PMID- 4373854
TI  - Immunochemotherapy of hepatoma in rats.

PMID- 4373855
TI  - Lymph flow augmentation secondary to increases in serum calcium.

PMID- 4373856
TI  - Estrogens and development of immobilization osteoporosis in rats.

PMID- 4373857
TI  - Neurotrophism in relation to muscle and nerve grafts in rats.

PMID- 4373858
TI  - Renin-angiotensin I activity in renin lymph during acute ureteral obstruction.

PMID- 4373859
TI  - Action of alpha receptors of sympathetic nervous system on urethra and its
      vasculature.

PMID- 4373860
TI  - Induction of aerobic metabolism by phosphocreatine following hemorrhagic shock.

PMID- 4373861
TI  - Deoxycorticosterone inhibits a viral tumor.

PMID- 4373862
TI  - Functional aspects of reinnervation of skin grafts.

PMID- 4373863
TI  - Development of the trigeminal ganglion.

PMID- 4373864
TI  - [Enzymes and the contractile capacity of the heart].

PMID- 4373865
TI  - [Treatment of patients with bronchial asthma and chronic pneumonia with
      cytochrome C in combination with other 0iologically active substances].

PMID- 4373866
TI  - [Reversible histochemical modifications of the rat adrenal cortex induced by a
      single injection of a synthetic corticotropin].

PMID- 4373867
TI  - [Aggregation inhibitors. The inhibition of platelet function by means of chemical
      substances].

PMID- 4373868
TI  - The inhibition of cancer cell stickness by the methylxanthine derivative
      pentoxifylline (BL 191).

PMID- 4373869
TI  - Contact activation of heparinized plasma.

PMID- 4373870
TI  - Stimulation of human platelet adenylate cyclase by prostaglandin D2.

PMID- 4373871
TI  - Relaxation of retracted clots: a thrombelastographic study.

PMID- 4373872
TI  - [Treatment of pathological fractures].

PMID- 4373873
TI  - [Oral contraceptives and liver cysts].

PMID- 4373874
TI  - Hypouricemic, mentally retarded infant with a defect of 5-phosphoribosyl-1
      pyrophosphate synthetase of erythrocytes.

PMID- 4373875
TI  - Hepatitis associated antigen in various clinical conditions especially in primary
      hepatoma and metastatic liver cancer.

PMID- 4373876
TI  - [Comparison between neutron and telecobalt therapy of bronchial, stomach and
      esophageal carcinoma].

PMID- 4373878
TI  - [Current status of radiotherapy of malignant germinal testicular neoplasms].

PMID- 4373877
TI  - [Radiotherapy of CNS tumors in children and adolescents. Experience and results
      of preferential use of high-energy electrons (20-35 MeV)].

PMID- 4373879
TI  - The effect of Dianabol on certain cell energy processes in postirradiation
      disease.

PMID- 4373880
TI  - Oxathiol effects on 210Po retention in the dogs' organs.

PMID- 4373881
TI  - The nuclear envelope: current problems of structure and of function.

PMID- 4373882
TI  - Feedback control mechanisms in micro-organisms and efficiency of growth.

PMID- 4373883
TI  - Lipid-protein interactions in the structure of biological membranes.

PMID- 4373885
TI  - [Some characteristics of the energy metabolism of the erythrocytes of pigeons and
      their nuclei].

PMID- 4373884
TI  - Progress in and deterrents to orthotopic liver transplantation, with special
      reference to survival, resistance to hyperacute rejection, and biliary duct
      reconstruction.

PMID- 4373886
TI  - [Adenylate cyclase system of the cell].

PMID- 4373887
TI  - [Inclusions in the nuclei of hepatocytes].

PMID- 4373888
TI  - [Vacuolization of skeletal muscle fibers. VII. Origin of vacuoles induced by
      direct current].

PMID- 4373889
TI  - [Effects of ionizing radiations on the activity of valyl-tRNA synthetase isolated
      from rat liver and Morris hepatoma 7777 (author's transl)].

PMID- 4373890
TI  - [End results of surgical treatment of 622 cases of tumors of the salivary glands
      (author's transl)].

PMID- 4373891
TI  - [Characterization of a Herpes simplex virus isolated from a lip tumor developing
      after recurrent herpes (author's transl)].

PMID- 4373892
TI  - Observations on the influence of ACTH on adrenal cholesterol metabolism.

PMID- 4373893
TI  - Some observations on arterial and venous levels of angiotensin II in man.

PMID- 4373895
TI  - Radiographic diagnosis of joint diseases.

PMID- 4373894
TI  - Biosynthesis, secretion and mechanism of action of parathyroid hormone.

PMID- 4373896
TI  - Interpretation of abdominal survey radiographs.

PMID- 4373897
TI  - Studies of feline viral rhinotracheitis vaccine.

PMID- 4373898
TI  - Placental and fetal manifestations of cytomegalovirus infection.

PMID- 4373899
TI  - Virus-induced cell pathology as viewed in the scanning electron microscope.

PMID- 4373900
TI  - Evolution and selective reduction of hormonal secretion in the mammotropic
      pituitary tumor (MtT-F4).

PMID- 4373901
TI  - [Continous inhibition of cell proliferation by oncogenous polyoma virus in rats
      (author's transl)].

PMID- 4373902
TI  - [Differential diagnosis of infectious mononucleosis in children].

PMID- 4373903
TI  - [Morphological changes in the liver of mice under the action of beta
      naphthylamine and alpha-naphthylamine].

PMID- 4373904
TI  - [Aromatic polycyclic hydrocarbon complex formation with DNA in an aqueous V with
      a neutral pH].

PMID- 4373905
TI  - [Stomach cancer metastases to the ovaries].

PMID- 4373907
TI  - [Humoral immunity in viral reticulosarcomatosis in mice].

PMID- 4373906
TI  - [Aggregate-hemagglutination method in the diagnosis of hepatocellular cancer and
      teratoblastomas].

PMID- 4373908
TI  - [Growth of Ronus virus transformed cultures of mammalian embryonal cells].

PMID- 4373909
TI  - [Mucoepidermoid cancer of the lung].

PMID- 4373910
TI  - [Antitumor resistance in immunizing animals with normal syngeneic tissues].

PMID- 4373911
TI  - [Malignant chemodectoma of the anterior mediastinum].

PMID- 4373912
TI  - [Cyclic adenosine monophosphate and prostaglandins in oncology].

PMID- 4373913
TI  - [Treatment of retroperitoneal tumors].

PMID- 4373914
TI  - [Interaction of sarcolysine with the DNA from tumorous and homologous normal
      tissues].

PMID- 4373916
TI  - [X-ray diagnosis of an intra-articular synovial sarcoma].

PMID- 4373915
TI  - [Trepan-biopsy of breast tumors].

PMID- 4373917
TI  - [Treatment of precancerous diseases and skin tumors by laser irradiation with the
      "Pulsar-1000"].

PMID- 4373918
TI  - [Carcinogenic properties of hydrazobenzene].

PMID- 4373919
TI  - [Sensitivity of the embryonic cells of the Djungarian hamster to the mutagenic
      and transforming action of certain oncogenic viruses in vitro].

PMID- 4373921
TI  - [The intermembranous spaces of the optic nerve in papilledema].

PMID- 4373920
TI  - [Erythropoietin as a nonspecific growth factor and its effect on carcinogenesis].

PMID- 4373922
TI  - [Ways and possibilities for increasing the radiosensitivity of brain tumors].

PMID- 4373923
TI  - [Structure of the capsid of isometrical viruses].

PMID- 4373924
TI  - [Detection of a viral interferon inducer in animal cells].

PMID- 4373925
TI  - [Possibility of Rous sarcoma virus reproduction in an in vitro transformed cell
      line from the embryo of the Armenian hamster Cricetulus migratorius Pal.)].

PMID- 4373926
TI  - [Serological control over the state of immunity to the poliomyelitis virus in
      children].

PMID- 4373927
TI  - [Formation of messenger RNA for interferon in cells treated with various viruses
      and poly-I:poly-C].

PMID- 4373928
TI  - [Sensitivity of female Japanese quail, their embryos and a cell culture of quail
      fibroblasts to infection by the avian adenovirus CELO].

PMID- 4373929
TI  - [Role of reovirus infection in the pathology of newborn infants and young
      children].

PMID- 4373930
TI  - [Editorial: Herpesviruses and oncogenesis].

PMID- 4373931
TI  - [Study of the biological properties of freshly isolated strains of adenovirus].

PMID- 4373932
TI  - [Experimental study of a mixed influenza and herpes viral infection].

PMID- 4373933
TI  - [Stabilization of the infectious activity of rhinovirus in prolonged storage].

PMID- 4373934
TI  - [Effect of reovirus infection on pregnant mice and their progeny].

PMID- 4373935
TI  - [Effect of hyperthermia on the infection caused by the smallpox vaccine virus].

PMID- 4373936
TI  - A new look at infectious gastroenteritis.

PMID- 4373937
TI  - [Rare complication of gastric carcinoma].

PMID- 4373938
TI  - [Cyclic 3', 5'-adenosine monophosphate levels in phytohaemagglutinin-stimulated
      and non-stimulated peripheral lymphocytes and in leukaemic cells (author's
      transl)].

PMID- 4373939
TI  - [Studies on purine de novo synthesis and cyclic AMP in normal and pathologic
      leukocytes (author's transl)].

PMID- 4373940
TI  - [Experimental investigations in guinea pigs on the therapy of gas gangrene with
      ozone. A preliminary report (author's transl)].

PMID- 4373941
TI  - [Severe myopathy and peripheral nerve disease in Cushing's syndrome due to
      adrenal cortex adenoma].

PMID- 4373942
TI  - [Clinical remarks to Iruxol-Salbe in local treatment of leg ulcer].

PMID- 4373944
TI  - [Indications for treatment of chronic hepatitis and liver cirrhosis and their
      complications. 1. Treatment of chronic hepatitis and liver cirrhosis].

PMID- 4373943
TI  - [Chemotherapy of brain neoplasms in children].

PMID- 4373946
TI  - [Electroneurography--methods and clinical use].

PMID- 4373945
TI  - [Ambulatory treatment of virus-related respiratory tract diseases. 2. Biology and
      diagnosis of viruses of the respiratory tract].

PMID- 4373948
TI  - [CO2-laser effects on peripheral medullated nerves].

PMID- 4373947
TI  - [Ambulatory treatment of virus related respiratory tract diseases. 1. Importance
      of virus related respiratory tract infections].

PMID- 4373949
TI  - [Experimental models for circulatory failure in hyperthermia under conditions of
      septic shock. Pressor reactions at various temperatures].

PMID- 4373950
TI  - [Cytomegalic ulcer of the cecum after kidney transplantation].

PMID- 4373952
TI  - [Exanthematous diseases caused by viruses of the herpes group].

PMID- 4373951
TI  - [Progresses in the field of immunodermatology].

PMID- 4373953
TI  - [Pulmonary metastases from a thyroid carcinoma in childhood after thorium-X
      treatment (author's transl)].

PMID- 4373954
TI  - [The diagnostic significance of red blood picture in Ivemark's syndrome
      (asplenia). 4 cases (author's transl)].

PMID- 4373956
TI  - [An automated method for the determination of chloride ions in serum, urine and
      sweat (author's transl)].

PMID- 4373955
TI  - [Investigation of methods for the immunological determination of lipoprotein-X(LP
      X) (author's transl)].

PMID- 4373958
TI  - [Microliter determination of glucose and xylose in blood using one-way 20 mul
      capillaries for blood collection (author's transl)].

PMID- 4373957
TI  - [Lactate determination with acetylpyridine adenine dinucleotide (APAD) (author's
      transl)].

PMID- 4373959
TI  - [Enzymatic endpoint determination of xylitol (author's transl)].

PMID- 4373960
TI  - [Photometric determination of copper in serum without deproteinization (author's
      transl)].

PMID- 4373961
TI  - [The determination of ammonia in the urine of premature and full-term newborns:
      comparison of the formal titration and the enzymic NH4+ determination (author's
      transl)].

PMID- 4373962
TI  - A simple, kinetic procedure for the optimized determination of the activity of
      serum glutamate dehydrogenase (EC 1.4.1.2.) with an enzyme analyzer.

PMID- 4373963
TI  - [Specific determination of corticosterone and cortisol in the nanogramm-range].

PMID- 4373964
TI  - [Inactivation of alpha-L-asparaginyl-angiotensin II by erythrocytes from healthy
      persons, and from patients with various forms of hypertension, or liver
      diseases].

PMID- 4373965
TI  - Analysis of catecholamines, serotonin and their metabolites by ion pair partition
      and modern liquid chromatography.

PMID- 4373966
TI  - True Arrhenius relationship of human lactate dehydrogenase.

PMID- 4373967
TI  - The effect of dilution and substrate repletion on the fluormetric determination
      of lactate dehydrogenase (LDH) isoenzymes of sera with high LDH activities.

PMID- 4373968
TI  - Determination of plasma cortisol by an enzymic fluorometric method.

PMID- 4373970
TI  - Specific coupling of nicotinamide adenine dinucleotide (NAD) to polymer supports.

PMID- 4373969
TI  - Preparation of specific solid supports from p-nitrophenyl substituted
      polyacrylamide gels. Affinity chromatography of cAMP specific enzymes.

PMID- 4373972
TI  - Preparation and properties of an antibody to human low density lipoprotein.

PMID- 4373971
TI  - A comparison of three methods of human plasma low density lipoprotein analysis.

PMID- 4373974
TI  - Application of electron spin resonance to the study of alpha-amylase activity.

PMID- 4373973
TI  - Analysis of metobolites in human biopsies by means of analytical
      isotachophoresis.

PMID- 4373975
TI  - Circadian rhythm of the renin-angiotensin-aldosterone system.

PMID- 4373976
TI  - Liver tumours in CF-1 mice exposed for limited periods to technical DDT.

PMID- 4373977
TI  - [Immuno-histochemical study of brain specific S-100 protein in experimental brain
      tumours].

PMID- 4373978
TI  - [Molecular mechanisms of cytoreception of estrogens].

PMID- 4373979
TI  - [Physiological role of polynucleotide phosphorylase].

PMID- 4373980
TI  - [Cyclic adenosine-3',5'-monophosphate and neuronal functions].

PMID- 4373982
TI  - [Regulation of biosynthesis of vitamin coenzymes in micro-organisms].

PMID- 4373981
TI  - [DNA ligases].

PMID- 4373983
TI  - [Effects of sodium hydroxybutyrate on interneuronal transmission of exitation at
      various levels of the central nervous system].

PMID- 4373984
TI  - [Specificity of neurochemical mechanisms involved in painful stimulations of the
      neurons of various formations of the brain of rabbits].

PMID- 4373985
TI  - [Functional changes in the hypophysis and adrenal gland cortex in climacteric].

PMID- 4373986
TI  - [Changes in pituitary ACTH reserve during hormonal contraception].

PMID- 4373988
TI  - [Effect of the Ent plasmid on the sensitivity of E. coli cells to the lethal
      action of UV light].

PMID- 4373987
TI  - [Effect of adrenaline and cyclic 3',5'-adenosine monophosphate on the glycogen
      synthetase activity of the developing skeletal muscles of chickens].

PMID- 4373989
TI  - Studies on electron spin resonance of Cu2+ complexes with nucleosides.

PMID- 4373990
TI  - Solubilization of collagen fibrils by human leucocyte collagenase activated by
      rheumatoid synovial fluid.

PMID- 4373992
TI  - The prevalence of hypertension in an unselected population, and the frequency of
      abnormalities of potassium, angiotensin II and aldosterone in hypertensive
      subjects.

PMID- 4373991
TI  - The role of cyclic adenosine 3',5'-monophosphate in the synthesis of the enzymess
      of gamma-aminobutyrate breakdown in Escherichia coli K-12.

PMID- 4373993
TI  - [Effect of noradrenaline and angiotensin on blood pressure and cerebral
      circulation in dogs, following administration via the vertebral artery].

PMID- 4373994
TI  - Borderline hypertension: correlation between the cardiac output and the vascular
      reactivity to norepinephrine.

PMID- 4373995
TI  - A correlation between plasma renin activity and the pressor response to
      angiotensin II.

PMID- 4373996
TI  - Problems of the management of insulinomas. Review of 132 cases treated with
      medical measures.

PMID- 4373997
TI  - On the decrease curve of leukemic cells and the treatment of acute leukemia.

PMID- 4373998
TI  - [Occurrence of nucleotide phosphatases in the ependyma of the third ventricle in
      the rat].

PMID- 4373999
TI  - [Fluorometric determination of the relative virus quantity in cells (author's
      transl)].

PMID- 4374000
TI  - [Ultrastructural elements supporting the neuronal lineage of the medulloblastoma
      (author's transl)].

PMID- 4374001
TI  - [The stiff-man syndrome. Clinical, polygraphical and histoenzymological study
      (author's transl)].

PMID- 4374002
TI  - Effect of phytohemagglutinin, basic protein and measles antigen on myo-(2
      3H)inositol incorporation into phosphatidylinositol of lymphocytes from patients
      with multiple sclerosis.

PMID- 4374003
TI  - The cerebral copper-protein complexes in hepato-lenticular degeneration studied
      by means of electron-spin-resonance technique.

PMID- 4374004
TI  - Peripheral nerve involvement in leprosy: quantitative histologic aspects.

PMID- 4374006
TI  - Primary intracranial adenoid cystic carcinoma (cylindroma). An electron
      microscopic study.

PMID- 4374005
TI  - Chloroquine-enhanced cerebellovascular changes in nutritionally imbalanced
      chicks.

PMID- 4374007
TI  - New linear accelerator for radiation therapy. A preliminary report.

PMID- 4374008
TI  - Fast neutron therapy. Past and present.

PMID- 4374009
TI  - Corrections of isodose diagrams for 60Co and 35 MeV electrons at penetration of
      lung tissue.

PMID- 4374010
TI  - Physical aspects on dose planning in treatment of mammary carcinoma.

PMID- 4374011
TI  - Radiation dosimetry with exoelectron emitting materials.

PMID- 4374012
TI  - Dosimetric investigation of postoperative irradiation of regional lymph nodes in
      mammary carcinoma.

PMID- 4374013
TI  - Individual plastic casts for radiation treatment.

PMID- 4374014
TI  - Small gas-tight ionization chambers for absorbed dose control during radiation
      therapy.

PMID- 4374016
TI  - Computerised system for scintigraphy.

PMID- 4374015
TI  - The radionuclide imaging process.

PMID- 4374017
TI  - Spectrum stabilization on a whole body counter with three detectors.

PMID- 4374018
TI  - Quantitative evaluation of isotope nephrograms.

PMID- 4374019
TI  - Computer evaluation of scintigraphic images.

PMID- 4374020
TI  - The mineral content in bone. Measured by means of 27.5 keV radiation from 125I.

PMID- 4374021
TI  - Computer processing of scintigraphic images.

PMID- 4374023
TI  - The dot counting method in scintigraphy.

PMID- 4374022
TI  - Digital stereoscintigraphy.

PMID- 4374024
TI  - A new whole body monitoring laboratory.

PMID- 4374025
TI  - Measurement of the resolution of a gamma camera system.

PMID- 4374026
TI  - Transit dose in extracorporeal blood irradiation devices measured by means of
      thermoluminescence.

PMID- 4374027
TI  - Cryosurgery. Principles and application to tonsillectomy.

PMID- 4374028
TI  - Dosimetry by extracorporeal irradiation of blood.

PMID- 4374029
TI  - Measuring methods for clinical investigation of the middle ear.

PMID- 4374030
TI  - Optical data processing. Principles and application to EEG audiometry.

PMID- 4374031
TI  - Beta and gamma radiochromatography with spark chambers.

PMID- 4374032
TI  - Treatment couch according to the Malmo system.

PMID- 4374033
TI  - Safety aspects of modern medical linear accelerators.

PMID- 4374034
TI  - Instrument for dose rate measurements in gynaecologic radiation therapy.

PMID- 4374036
TI  - Analytic approximation of the dose distribution from a 6 MeV linear accelerator.

PMID- 4374035
TI  - Skin doses for electrons in the energy range 10 to 33 MeV. Measurements with
      thermoluminescence dosimeters.

PMID- 4374037
TI  - Depth dose near the surface by fast electron irradiation. Measurements with
      thermoluminescence dosimetry.

PMID- 4374038
TI  - Automation in radiation therapy.

PMID- 4374039
TI  - Treatment of Hodgkin's disease by radiation therapy.

PMID- 4374040
TI  - A digital electrometer.

PMID- 4374041
TI  - Irradiation of the thorax. Comparison between 60Co gamma rays, 6 MeV roentgen
      rays and 30 MeV electrons.

PMID- 4374044
TI  - 45 MeV betatron for radiation therapy.

PMID- 4374043
TI  - The importance of two independent integrating monitoring systems in medical
      accelerators.

PMID- 4374042
TI  - Radiophysical means for adequate radiation therapy with supervoltage apparatus at
      Radiumhemmet.

PMID- 4374045
TI  - The effect of cadmium on catecholamines and angiotensin responses in the dog
      kidney.

PMID- 4374046
TI  - Ultrastructure of the ribonucleoprotein and messenger-like ribonucleic acid of
      the polyribosomes isolated from Rous sarcoma virus-induced mouse ascites sarcoma
      cells.

PMID- 4374047
TI  - Effect of immunization with fetal cells on adenovirus-12 oncogenesis.

PMID- 4374048
TI  - The role of cyclic nucleotide on fetal and neonantal erythropoiesis.

PMID- 4374049
TI  - Attempts to isolate virus from human brain tumors.

PMID- 4374050
TI  - Epstein-Barr virus (EBV) infections in army recruits.

PMID- 4374051
TI  - Advances in penicillin research.

PMID- 4374052
TI  - An outbreak of arthrogryposis and hydranencephaly syndrome affecting calves in
      Israel: a retrospective epidemiological study.

PMID- 4374053
TI  - Studies of the nicotinic receptor-response mechanism in Torpedo postsynaptic
      membranes.

PMID- 4374054
TI  - Membranes of adrenal medulla: their role in exocytosis.

PMID- 4374055
TI  - Binding of ADP and ATP to mitochondrial protein and its possible involvement in
      the mechanism of oxidative phosphorylation.

PMID- 4374056
TI  - Modification of the secretory granule during secretion in the rat parotid gland.

PMID- 4374057
TI  - Interactions of membranes, microfilaments, and microtubules in endocytosis and
      exocytosis.

PMID- 4374058
TI  - The molecular organization of the beta granule of the islets of Langerhans.

PMID- 4374059
TI  - Molecular basis of enzyme secretion by the exocrine pancreas.

PMID- 4374060
TI  - The relation between cholinergic and monoaminergic activity in the caudate
      nucleus.

PMID- 4374061
TI  - The pathology of Parkinsonism: a comparison of degenerations in cerebral cortex
      and brainstem.

PMID- 4374062
TI  - Depigmentation in the nerve cells of the substantia nigra and locus ceruleus in
      Parkinsonism.

PMID- 4374063
TI  - Biochemistry of neuromelanin.

PMID- 4374064
TI  - Free radicals in the human nervous system.

PMID- 4374065
TI  - Dopaminergic involvement in hypothalamic function: extrahypothalamic and
      hypothalamic control. A neuroanatomical analysis.

PMID- 4374067
TI  - Central noradrenergic neurons.

PMID- 4374066
TI  - Catecholaminergic control of gonadotropin and prolactin secretion with particular
      reference to the possible participation of dopamine.

PMID- 4374068
TI  - The role of brain catecholamines in the regulation of ACTH secretion.

PMID- 4374069
TI  - Mechanisms involved in the control of extrapyramidal dysfunctions and in striatal
      dopamine synthesis.

PMID- 4374070
TI  - The use of protoplasts and separated cells in plant virus research.

PMID- 4374071
TI  - Remarks on the ultrastructure of type A, B, and C virus particles.

PMID- 4374072
TI  - Plant viruses with a multipartite genome.

PMID- 4374073
TI  - [On the causative agent of acute haemorrhagic conjunctivitis and its epidemiology
      (author's transl)].

PMID- 4374074
TI  - On the problem of heredity in hypersomnia, narcolepsy and dissociated sleep
      disturbances.

PMID- 4374076
TI  - Trophoblastic disease II. Trophoblastic invasion.

PMID- 4374075
TI  - Trophoblastic disease I.

PMID- 4374077
TI  - Trophoblastic disease III. Choriocarcinoma and related diseases.

PMID- 4374078
TI  - Blood flow through the thyroid gland in rats.

PMID- 4374079
TI  - Vinca alkaloids. Experimental and clinical trials.

PMID- 4374080
TI  - PR aside: initial results from NIMH's service program evaluation studies.

PMID- 4374081
TI  - The role of viruses in congenital defects.

PMID- 4374082
TI  - Concomitant Mycoplasma and adenovirus infection in a family.

PMID- 4374083
TI  - Radioimmunoassay of alpha-fetoprotein in human serum: clinical value in patients
      with liver diseases.

PMID- 4374084
TI  - Rational use of psychotropic drugs. I. Hypnotics.

PMID- 4374085
TI  - Cushing's disease with cure by resection of a pituitary adenoma. Evidence against
      a primary hypothalamic defect.

PMID- 4374086
TI  - Cell surface contributions to the malignant process.

PMID- 4374087
TI  - Statistical correlation of uveitis syndromes with virus titers.

PMID- 4374088
TI  - Parathyroid hormone stimulation of glucose and urea production in isolated liver
      cells.

PMID- 4374090
TI  - Facilitation of transmitter release at the mammalian neuromuscular junction.

PMID- 4374089
TI  - Renal function in dogs with acute selective hepatic venous outflow block.

PMID- 4374091
TI  - Effect of parathormone and cyclic adenosine monophosphate on renal bicarbonate
      reabsorption.

PMID- 4374093
TI  - MEPP frequency distribution in rat diaphragm under vitamin E deficiency.

PMID- 4374094
TI  - Effects of phosphate depletion and parathyroid hormone on renal glucose
      reabsorption.

PMID- 4374092
TI  - Alterations in pharmacologic receptor activity by dithiothreitol.

PMID- 4374095
TI  - Theophylline, cyclic AMP, choleragen, and electrolyte transport by rabbit ileum.

PMID- 4374096
TI  - Comparison of the biochemical composition of four preparations of contracting
      cardiac muscle.

PMID- 4374097
TI  - Partial resection of the liver for primary cholangiocarcinoma. Presentation of a
      successful case.

PMID- 4374098
TI  - Inhibition of gastric acid secretion by extract of WDHA tumor.

PMID- 4374100
TI  - Enzymatic liberation of myogenic cells from adult rat muscle.

PMID- 4374099
TI  - [The influence of hormones on some metabolic processes in aqueous humor and
      ciliary body (author's transl)].

PMID- 4374101
TI  - Blood vessel wall characteristics in experimental hypertension.

PMID- 4374102
TI  - The replication of herpes viruses.

PMID- 4374103
TI  - Conference on the scientific basis of respiratory therapy. Aerosol therapy.
      Steroid and antibiotic aerosols.

PMID- 4374105
TI  - Extra-adrenal retroperitoneal paraganglioma.

PMID- 4374104
TI  - Intracellular metabolism of oxygen.

PMID- 4374106
TI  - [Herpetic superinfection of the Kaposi-Juliusberg syndrome type in a mother and
      daughter with Darier's disease].

PMID- 4374107
TI  - [A case of calcified mucoid gastric cancer].

PMID- 4374108
TI  - [Australia antigen. Hepatocytes with "ground-glass" cytoplasm. Apropos of a
      hepatoma in cirrhosis with Australia antigen and "ground-glass" hepatocytes].

PMID- 4374109
TI  - [Neurological complications of treatments with vincristine. Clinical study of 100
      patients treated with vincristine].

PMID- 4374111
TI  - Accuracy, sensitivity, and specificity of electron spin resonance analysis of
      mineral constituents of irradiated tissues.

PMID- 4374110
TI  - [Migratory neuralgia: a symptom revealing Besnier-Boeck-Schaumann disease].

PMID- 4374113
TI  - Treatment of shrinkage diseases of the conjunctiva.

PMID- 4374112
TI  - Ocular complications in renal transplant patients.

PMID- 4374114
TI  - [Regeneration of used mercuric and potassium iodide for an economical use in egg
      counts routines (author's transl)].

PMID- 4374115
TI  - [Ultrastructural study of 5'nucleotidase activities in monolayer culture of rat
      hepatocytes (author's transl)].

PMID- 4374116
TI  - Pheromones as a means of genetic control of behavior.

PMID- 4374117
TI  - Regulation: positive control.

PMID- 4374118
TI  - Genetics of DNA tumor viruses.

PMID- 4374119
TI  - Test method for the evaluation of virucidal efficacy of three common liquid
      surface disinfectants on a simulated environmental surface.
AB  - The Association of Official Analytical Chemists bacterial use-dilution test for
      evaluating liquid surface disinfectants was modified to determine the efficacy of
      three common environmental germicide compounds against representatives of four
      virus groups. Modifications were made to conform to the Environmental Protection
      Agency guidelines on virucidal testing procedures. Alterations included: the use
      of a concentrated tissue culture preparation of virus instead of a standard
      bacterial culture; HEp-2 tissue culture cells as a visible test system in place
      of standard nutrient broth; and controls to measure the virus titer end point and
      the toxicity of the disinfectant to the cell cultures. Comparison of control end
      points with results from the test proper were the measure of the effectiveness of
      the germicides against the viruses. Results are described which agree with those
      based on other methods previously reported.

PMID- 4374120
TI  - Recovery of heated Clostridium perfringens type A spores on selective media.
AB  - The enumeration of Clostridium perfringens spores on sulfite-polymyxin
      sulfadiazine agar (SPS), tryptone-sulfite-neomycin agar (TSN), Shahidi-Ferguson
      perfringens agar (SFP), tryptone-sulfite-cycloserine agar (TSC), and TSN lacking
      antibiotics (BASE) was studied. The spores were heated at 105 to 120 C by the
      capillary-tube method. The media were about equally efficient for the enumeration
      of heat-activated spores. Efficiency of the media for the recovery of spores
      surviving heat treatments at ultrahigh temperatures varied as follows: TSC >/=
      SFP > BASE > SPS > TSN. Greater recovery when survivors were enumerated on TSC or
      SFP was attributed to germination of injured spores by the lysozyme present in
      the egg yolk emulsion used in these media. Low recovery of survivors on TSN and
      SPS was due to both the absence of lysozyme and inhibition of injured spores by
      the selective agents of these media. Recovery of heated spores was reduced
      greatly by polymyxin, neomycin, and kanamycin, and slightly by sulfadiazine and D
      cycloserine. The addition of lysozyme to SPS or TSN did not improve the
      percentage of heat-injured spores recovered because the selective agents of these
      media interfered with the action of lysozyme. The suitability of the selective
      media for the enumeration of survivors was greatly affected by the presence of
      certain foods.

PMID- 4374121
TI  - Cold shock lethality and injury in Clostridium perfringens.
AB  - Several observations have been made in regard to cold shock lethality of
      Clostridium perfringens: (i) loss of viability was not consequence of exposure of
      the cells to air; (ii) stationary-phase cells were much more resistant to cold
      shock at 4 C than exponential-phase cells; (iii) at 4 C 96% of an initial
      population of exponential-phase cells was killed upon cold shock and 95% of the
      remaining population was killed within 90 min of continued exposure at 4 C; (iv)
      the minimal temperature differential for detectable cold shock lethality was
      between 17 and 23 C, and the maximum beyond which lethality was not appreciably
      increased was between 28 and 33 C. Up to 75% of viable cold-shocked cells were
      injured, as demonstrated by cold shocking late exponential-phase cells at 10 C
      and using differential plating procedure for recovery. Repair of injury was
      temperature dependent, and occurred in a complex medium and 0.1% peptone but not
      water. Nalidixic acid, chloramphenicol, and rifampin did not inhibit repair of
      injury.

PMID- 4374122
TI  - Chemical disinfection of holding-tank sewage.
AB  - A number of chemical disinfectants were evaluated for their bactericidal and
      virucidal effectiveness in holding-tank sewage. It was found that the
      disinfection efficiencies of formaldehyde, benzalkonium chloride, cetylpyridinium
      chloride, and methylene blue were markedly improved if the pH of the sewage was
      raised from 8.0 to 10.5. When formaldehyde, benzalkonium chloride, and methylene
      blue were tested with either 2-week holding times with no sewage additions or 10
      day holding times with daily sewage additions, disinfection effectiveness was
      maintained as long as the sewage pH was kept at 10.5 and the disinfectant
      concentration was kept at 100 mg/liter or more. Calcium hypochlorite, zinc
      sulfate, and phenol were found to be relatively ineffective disinfectants for
      holding-tank sewage.

PMID- 4374123
TI  - Simplified method for the preparation of silica gel media.
AB  - A simplified and reliable method for the preparation of a variety of silica gel
      media is described. The growth of common microorganisms on these media was
      examined.

PMID- 4374124
TI  - Response of ligated intestinal loops in chickens to the enterotoxin of
      Clostridium perfringens.
AB  - Approximately 45-cm length of jejunoileum of 7-week-old chickens was found to be
      responsive and suitable for testing the enterotoxin of Clostridium perfringens by
      the ligated intestinal loop technique. Injections of 20 to 30 mug of enterotoxin
      per loop caused positive response of fluid accumulation. Chickens were found to
      be more convenient and economical for this purpose than other laboratory and
      domestic animals.

PMID- 4374125
TI  - Persistence of enteroviruses in lake water.
AB  - Two enteroviruses were inactivated more rapidly in a lake than in sterile lake
      water; then their coat proteins were degraded and, perhaps, used by
      microorganisms.

PMID- 4374127
TI  - Partial specificity of low-molecular weight RNA that stimulates RNA synthesis in
      various tissues.

PMID- 4374126
TI  - The effect of Zn2+ ions on mitochondrial electron transport.

PMID- 4374128
TI  - The effect of essential amino acid deprivation on macromolecular synthesis and
      nucleotide pool sizes in Neurospora crassa.

PMID- 4374129
TI  - Alterations in glucose metabolism in chick embryo cells transformed by Rous
      sarcoma virus. Transformation-specific changes in the activities of key enzymes
      of the glycolytic and hexose monophosphate shunt pathways.

PMID- 4374130
TI  - Occurrence of initiation factor 2 in the postribosomal fraction and
      identification of an initiation inhibitor as elongation factor G.

PMID- 4374131
TI  - Concanavalin A and wheat germ agglutinin receptor activity of sialoglycopeptides
      isolated from the surface of Novikoff hepatoma cells.

PMID- 4374132
TI  - Reduced nicotinamide adenine dinucleotide-cytochrome b5 reductase and cytochrome
      b5 as electron carriers in NADH-supported cytochrome P-450 -dependent enzyme
      activities in liver microsomes.

PMID- 4374133
TI  - Absence of high-affinity adenosine 3',5'-monophosphate binding sites from the
      cytosol of three hepatic-derived cell lines.

PMID- 4374134
TI  - D2O effects on association behavior and binding properties of phospho- and
      dephospho-cytoplasmic malic dehydrogenase.

PMID- 4374135
TI  - Mechanism of aromatic hydroxylation. Properties of a model for pyridine
      nucleotide-dependent flavoprotein hydroxylases.

PMID- 4374136
TI  - Resonance Raman spectra of the b- and c-type cytochromes of succinate-cytochrome
      c reductase.

PMID- 4374137
TI  - Properties of purified kidney microsomal NADPH-cytochrome c reductase.

PMID- 4374138
TI  - Structural implications derived from the analysis of electron paramagnetic
      resonance spectra of natural and artificial copper proteins.

PMID- 4374139
TI  - Calcium-dependent cyclic nucleotide phosphodiesterase from glial tumor cells.

PMID- 4374140
TI  - [Recent interpretations and persistent obscurity of the biological significance
      of nonchromaffin paraganglioma].

PMID- 4374141
TI  - [Disontogenetic neoplasms in the female genital tract. Formal and onto
      histogenetic differences between mixed mesodermal tumor, mullerian tumor and
      stromatic sarcoma of the uterus].

PMID- 4374142
TI  - Advances in lipoprotein research. Biochemical and clinical aspects.

PMID- 4374143
TI  - Pharmacological receptors and the control of cell function.

PMID- 4374144
TI  - Modulation of trigeminal reflexes during the REM state in brain transected cats.

PMID- 4374145
TI  - Paget's disease of the breast.

PMID- 4374146
TI  - [Demonstration of genetic markers in dental pulp].

PMID- 4374147
TI  - Studies on a gram-positive hydrogen bacterium, Nocardia opaca 1 b. III.
      Purification, stability and some properties of the soluble hydrogen
      dehydrogenase.

PMID- 4374149
TI  - Characterization of amino acid pools in the vacuolar compartment of Saccharomyces
      cerevisiae.

PMID- 4374148
TI  - A phototrophic gliding filamentous bacterium of hot springs, Chloroflexus
      aurantiacus, gen. and sp. nov.

PMID- 4374150
TI  - Linkage of the Salmonella typhimurium chromosomal loci encoding for the
      cytochrome-linked L-alpha-glycerophosphate dehydrogenase and amylomaltase
      activities.

PMID- 4374153
TI  - [Estrogen therapy of excessive height in girls].

PMID- 4374151
TI  - Regulation of biosynthesis of aspartate family amino acids in the photosynthetic
      bacterium Rhodopseudomonas palustris.

PMID- 4374152
TI  - [Fanconi's disease and cancer of the liver].

PMID- 4374154
TI  - [Hypercalcemia associated with nephroblastoma: paraneoplastic syndrome in a young
      child].

PMID- 4374155
TI  - Drug and sociotherapy in the aftercare of schizophrenic patients. II. Two-year
      relapse rates.

PMID- 4374156
TI  - Drug and sociotherapy in the aftercare of schizophrenic patients. III. Adjustment
      of nonrelapsed patients.

PMID- 4374157
TI  - Sleep amphetamine effects in MBDS and normal subjects.

PMID- 4374158
TI  - Analysis of minimal functions of simian virus 40. IV. Oncogenic transformation of
      syrian hamster kidney cells in vitro by beta-propiolactone inactivated sv40.

PMID- 4374159
TI  - Complement-requiring neutralizing antibodies in cattle to infectious bovine
      rhinotracheitis virus.

PMID- 4374160
TI  - A simple method for the quantification of 140S particles of foot-and-mouth
      disease virus (FMDV).

PMID- 4374161
TI  - Varicella virus isolation from spinal ganglion.

PMID- 4374162
TI  - Study of poliovirus multiplication in different animal species using
      photosensitized virus strains.

PMID- 4374163
TI  - Inhibition of giant cell formation by Compound 48-80 after infection with
      herpesvirus hominis. III. Binding of tritium-labelled Compound 48-80 to normal
      and infected cells and its action upon phosphatidyl-choline-biosynthesis.

PMID- 4374164
TI  - Inhibition of giant cell formation by Compound 48-80 after infection with
      herpesvirus hominis. IV. Compound 48-80, an inhibitor of choline kinase activity.

PMID- 4374165
TI  - Herpes simplex viruses types 1 and 2. Type and strain specific characteristics
      affecting virus plaque formation.

PMID- 4374166
TI  - The properties of intracellular paramyxovirus ribonucleoprotein in a
      nonpermissive system.

PMID- 4374167
TI  - Improvement of methods for intratypic differentiation of polioviruses. I. Agar
      gel diffusion precipitation test with repeated addition of antigens for
      differentiation between wild and vaccine polioviruses type 1 and 2.

PMID- 4374168
TI  - Improvement of methods for intratypic differentiation of polioviruses. II. Use of
      strain-specific antisera cross-adsorbed with antigens of heterologous strains in
      agar gel diffusion precipitation test for differentiation between wild and
      vaccine strains of poliovirus typess 1,2 and 3.

PMID- 4374169
TI  - Improvement of methods for intratypic differentiation of polioviruses. III.
      Neutralization test with cross-adsorbed sera for differentiation between wild and
      vaccine strains of polioviruses.

PMID- 4374170
TI  - Properties of SV40 rescued from actinomycin D-sensitive and actinomycin D
      resistant transformed hamster cells. I. Lytic infection.

PMID- 4374172
TI  - [Metabolic effects of caffeine: role of the central nervous system and of cyclic
      AMP].

PMID- 4374171
TI  - [Biopharmacological effects of coffee. Recent findings on adenyl cyclase
      phosphodiesterase system and its factors which do not change activity].

PMID- 4374173
TI  - [Histological and histochemical characteristics of the stroma of stomach cancer].

PMID- 4374174
TI  - [Histochemical study of acid phosphatase in tumor cells of stomach cancer].

PMID- 4374175
TI  - Subependymal germinolysis.

PMID- 4374176
TI  - The thrombotic syndrome associated with carcinoma. A clinical and neuropathologic
      study.

PMID- 4374177
TI  - Regulation of lactate dehydrogenase activity in Actinomyces viscosus by adenosine
      5'-triphosphate.

PMID- 4374178
TI  - Letter: Aerosol administration of the SA-2 vaccine strain of infectious
      laryngotracheitis virus.

PMID- 4374180
TI  - [Synovial cell cultures for the study of the pathogenesis of rheumatoid arthritis
      (author's transl)].

PMID- 4374182
TI  - Hepatic parenchyma weight changes in the presence of primary and secondary tumors
      of the liver: a morphometric study.

PMID- 4374181
TI  - Structure and function of the stimulated adrenal cortex. 2. Early effects of ACTH
      on the ultrastructure of the zona fasciculata in dexamethasone--treated rats.

PMID- 4374183
TI  - Karyometric studies of thioacetamide-induced hepatomas.

PMID- 4374185
TI  - Concentration of elongation factor 2 in rat skeletal muscle during protein
      depletion and re-feeding.
AB  - Rat skeletal-muscle elongation factor 2 was assayed by causing it to react with
      NAD(+) by using fragment A of diphtheria toxin as the catalyst. Dietary protein
      restriction decreased the concentration of elongation factor 2 in homogenates of
      whole muscle. These decreases paralleled a decline in muscle RNA so that the
      number of molecules of elongation factor 2 per ribosome appeared to be
      independent of the diet. We conclude that elongation factor 2 is probably not the
      factor limiting the rate of muscle protein synthesis and is not responsible for
      the fall in the protein-synthetic rate in vivo observed in the muscles of animals
      whose dietary protein intake is inadequate.

PMID- 4374184
TI  - Role of cyclic adenosine 3':5'-monophosphate in the action of 1,1,1-trichloro-2,2
      bis-(p-chlorophenyl)ethane (DDT)on hepatic and renal metabolism.
AB  - The possibility whether alterations in the cyclic AMP-adenylate cyclase
      phosphodiesterase system play a role in the action of 1,1,1-trichloro-2,2-bis-(p
      chlorophenyl)ethane (DDT) on hepatic and renal carbohydrate metabolism was
      investigated. Administration of exogenous cyclic AMP (10mg/100g) was found to
      mimic the action of DDT which enhanced the activities of pyruvate carboxylase,
      phosphoenolpyruvate carboxylase, fructose 1,6-diphosphatase and glucose 6
      phosphatase in both liver and kidney cortex, elevated the concentration of blood
      glucose and urea and decreased the amount of hepatic glycogen. Treatment with
      theophylline augmented the effects of a submaximal dose of this halogenated
      hydrocarbon on serum urea and glucose as well as the key gluconeogenic enzymes in
      liver and kidney cortex. Addition of DDT in vitro to liver and kidney homogenates
      resulted in a significant enhancement of adenylate cyclase activity. Hepatic and
      renal slices from rats already treated with DDT displayed an increased ability to
      convert [(3)H]adenosine into cyclic [(3)H]AMP. Whereas kidney-cortex slices
      excised from rats given caffeine and DDT produced an even greater amount of
      cyclic [(3)H]AMP, imidazole, propranolol and hydrazine prevented the insecticide
      stimulated rise in cyclic nucleotide production. In contrast, prostaglandin E(1)
      failed to exert any significant effect on DDT-induced increases in cyclic
      [(3)H]AMP synthesis from radioactive adenosine. The present study and our
      previous findings (Kacew & Singhal, 1973e) support the concept that the DDT
      induced alterations in carbohydrate metabolism of liver and kidney cortex may be
      related to an initial stimulation of the cyclic AMP-adenylate cyclase system in
      these tissues.

PMID- 4374186
TI  - Metabolism of dihydrotachysterol and 5,6-trans-cholecalciferol in the chick and
      the rat.
AB  - Dihydrotachysterol and 5,6-trans-cholecalciferol are biologically active
      analogues of cholecalciferol (vitamin D) with a similarity in steric structure to
      1,25-dihydroxycholecalciferol, the active form of the vitamin. The question
      arises as to the nature of the active form of these analogues. High specific
      radioactivity (14)C- and (3)H-labelled forms of dihydrotachysterol and 5,6-trans
      cholecalciferol and its 25-hydroxy derivative were synthesized and their
      metabolism was studied in chicks and rats. All these steroids were very rapidly
      metabolized compared with cholecalciferol; 20% of the dihydrotachysterol dose was
      excreted in bile in the first 24h, about 50% as a carboxylic acid derivative.
      Although polar metabolites were detected in tissues, no 1-hydroxy form was
      observed. Larger proportions of the parent steroid and its 25-hydroxy metabolite
      were detected in tissues compared with cholecalciferol, but no single metabolite
      was detected at the intracellular site of action of cholecalciferol. It is
      suggested that analogues of cholecalciferol will be biologically active if they
      possess a hydroxyl group in the same steric position as that at C-1 of
      cholecalciferol, with the greatest activity shown by those that also have a C-25
      hydroxyl group. The implication of these findings for the chemical features
      necessary for binding to receptor proteins are briefly discussed.

PMID- 4374179
TI  - The latent herpes simplex virus.

PMID- 4374188
TI  - Properties of pyruvate dehydrogenase of rat mammary tissue and its changes during
      pregnancy, lactation and weaning.
AB  - Pyruvate dehydrogenase of rat mammary tissue showed many of the regulatory
      properties of the analogous enzyme in other mammalian tissues. It was inactivated
      in the presence of low concentrations of ATP and this rate of inactivation was
      slowed if pyruvate or PP(1) was also present. Reactivation by Mg(2+) in the
      presence of low concentrations of Ca(2+) occurred over a similar time-course. The
      K(m) value for Mg(2+) in this process was about 2mm. The enzyme was assayed in
      extracts of freeze-clamped mammary glands removed from pregnant, lactating or
      recently weaned rats under halothane anaesthesia. Both the initial activity and
      the activity after full activation (;total enzyme activity') were determined. The
      former parameter, when expressed on a DNA basis, varied within a range of 40
      times its lowest value. Maximum total enzyme activity was about 1 unit/g wet wt.
      The total enzyme activity and the fraction in the active form increased in step
      from pregnancy to mid-lactation, remained elevated until the end of lactation and
      then fell steeply within 3 days after weaning. The correlation of these two
      parameters of enzyme activity may indicate a common regulatory factor or else an
      interdependence arising from inherent properties of the multi-enzyme complex.

PMID- 4374187
TI  - A new method for the preparation of uniformly 14C-labelled compounds by using
      Anacystis nidulans.
AB  - 1. Growth conditions were devised which enabled Anacystis nidulans to be grown on
      high specific radioactivity (14)CO(2) (at over 98% isotopic abundance of (14)C)
      in a closed system with greater than 85% substrate utilization. 2. The DNA and
      RNA content of A. nidulans was estimated by various methods and compared with
      that of Chlorella pyrenoidosa. 3. A procedure was developed for the quantitative
      extraction and separation of the DNA and RNA from A. nidulans. 4. The
      fractionation and analysis of the DNA and RNA includes methods for the
      preparation of the uniformly (14)C-labelled deoxyribonucleoside monophosphates
      and the uniformly (14)C-labelled ribonucleoside monophosphates. 5. The base 6
      methylaminopurine was identified as a component of the DNA. 6. The preparation
      and total yield of uniformly (14)C-labelled amino acids from A. nidulans are also
      briefly described. The results are discussed in relation to the use of other
      micro-organisms for the preparation of compounds labelled with (14)C.

PMID- 4374189
TI  - The relationship between the concentration of adenosine 3':5'-cyclic
      monophosphate and the anti-lipolytic action of insulin in isolated rat fat-cells.
AB  - The relationship between cyclic AMP content and lipolysis, as measured by
      glycerol formation, was studied in isolated rat fat-cells. Inhibition of
      lipolysis by insulin in the presence of a low concentration of adrenaline was
      accompanied by little or no lowering of cyclic AMP content, measured after 15min
      incubation. The time-course of cyclic AMP content after addition of adrenaline
      showed that the effect of insulin in lowering cyclic AMP content measured after 2
      5min was gradually lost over the next hour, mainly because of the fall in cyclic
      AMP content after an early peak in the presence of adrenaline alone. There was a
      44% loss of immunoreactive insulin, from an initial concentration of 0.3nm,
      during a 1h incubation with fat-cells. Insulin did not affect partitioning of
      cyclic AMP between cells and incubation medium. When the correlation between
      cyclic AMP content and rate of lipolysis was investigated for a wide range of
      adrenaline concentrations, it was found that the lowering of cyclic AMP content
      by insulin was much less than that required to account for the amount of
      inhibition of lipolysis. It is concluded that inhibition of adrenaline-stimulated
      lipolysis by insulin involves factors in addition to a decrease in intracellular
      cyclic AMP concentration.

PMID- 4374190
TI  - Glycosyltransferases in the Golgi membranes of onion stem.
AB  - Cell fractions consisting largely of Golgi membranes were prepared from the
      meristematic region of the onion. Several enzyme activities were found to be
      localized in these fractions: inosine diphosphatase, galactosyltransferases and
      glucosyltransferases. The fractions catalysed the transfer of [(14)C]galactose
      from UDP-galactose to endogenous and cell-sap acceptors, to N-acetylglucosamine
      and to ovalbumin. In the presence of bovine alpha-lactalbumin, transfer to
      glucose (lactose synthesis) was catalysed. [(14)C]Glucose was transferred from
      UDP-glucose to endogenous and cell-sap acceptors, to cellobiose and to fructose
      (sucrose synthesis). All these activities were latent, being potentiated by
      detergents (Triton X-100 or sodium deoxycholate). The characteristics of some of
      these enzyme activities are described and their biological significance is
      discussed.

PMID- 4374191
TI  - The effect of energization on the apparent Michaelis-Mentne constant for oxygen
      in mitochondrial respiration.
AB  - Lineweaver-Burk plots of 1/v against 1/[O(2)] for rat liver mitochondrial
      respiration with succinate or ascorbate+NNN'N'-tetramethyl-p-phenylenediamine as
      substrates are non-linear. In state 3u (uncoupled by trifluoromethoxycarbonyl
      cyanide phenylhydrazone) such plots tend to be concave upward, whereas in state 4
      (energized) the plots were concave downward. The apparent K(m) for oxygen is
      larger in state 4 than in state 3u, despite the higher turnover in the latter
      system. It is postulated that at least one reversible reaction occurs between
      cytochrome c and cytochrome c oxidase, whose rate is increased on energization
      (reversed electron transfer); a model including such a reaction is proposed which
      accounts semiquantitatively for the observations.

PMID- 4374192
TI  - Mode of inhibition of mitochondrial energy transduction by
      chlorophenoxyisobutyrate.
AB  - 1. alpha-p-Chlorophenoxyisobutyric acid, the ethyl ester of which is widely used
      as an antihypercholesterolaemic drug, is an inhibitor of energy-transfer
      reactions in isolated rat liver mitochondria. 2. The compound at lower
      concentrations (<4.0mumol/mg of mitochondrial protein) inhibits state 3
      oxidation, stimulates state 4 oxidation, abolishes respiratory control and
      stimulates the latent adenosine triphosphatase activity of mitochondria. The
      inhibition imposed on state 3 oxidation is relieved by dinitrophenol. 3. At
      higher concentrations it inhibits coupled phosphorylation as well as
      dinitrophenol-stimulated adenosine triphosphatase activity. The inhibition of
      state 3 oxidation under these conditions is not reversed by uncouplers. 4. The
      three coupling sites of phosphorylation exhibit differential susceptibility to
      inactivation by this compound. Coupled phosphorylation at the first site is
      abolished at a drug concentration of 3.0mumol/mg of protein. The third site is
      inactivated when the concentration of the drug reaches 5.0mumol/mg of protein.
      The second site is the most refractory and drug concentrations of the order of
      10.0mumol/mg of protein are required effectively to inhibit phosphorylation at
      this site. 5. The compound also inhibits ATP-dependent reversal of electron
      transport as well as the adenosine triphosphatase activity in submitochondrial
      particles. 6. The oxidation of NADH and succinate in these particles is not
      inhibited. 7. These properties indicate that the compound acts as an ;inhibitory
      uncoupler' of energy-transfer reactions in isolated mitochondria.

PMID- 4374193
TI  - Measurement of the dynamics of stimulation and inhibition of steroidogenesis in
      isolated rat adrenal cells by using column perfusion.
AB  - Isolated adrenal cells were perfused in a small column by using Bio-Gel
      polyacrylamide beads as an inert supporting matrix, and the time-course of the
      response to various stimuli was observed by measuring fluorogenic 11
      hydroxycorticosteroids in the effluent. A small but significant response was
      observed 1 min after stimulation with physiological concentrations of ACTH
      (adrenocorticotrophin), but the response did not start to build up rapidly for 3
      4min and eventually reached a plateau after 9-10min. A similar pattern of events
      was observed for the decay of the steroid output on removal of ACTH. ACTH
      analogues, including one with a long duration of action in vivo, were found to
      produce responses with similar kinetics. However, cyclic AMP caused a more rapid
      increase in steroidogenesis and its effects were more short-lived after
      withdrawal. If, as present evidence suggests, cyclic AMP is produced rapidly
      after ACTH stimulation the delayed build-up of the steroidogenic response to ACTH
      would indicate that cyclic AMP may not be the intracellular mediator. When
      inhibitors were applied during ACTH stimulation, aminoglutethimide, which blocks
      mitochondrial conversion of cholesterol into pregnenolone (3beta-hydroxypregn-5
      en-20-one), caused a rapid fall in steroid output (1 min), whereas cycloheximide
      took longer to achieve its full effect. Nevertheless, the response had fallen by
      50% in 2 min, indicating a much shorter half-life than that previously reported
      for the labile protein implicated in steroidogenesis. In addition the rapid
      response to cyclic AMP makes it unlikely that steroid production is induced as a
      result of initiation of protein synthesis. This suggests that the labile protein
      plays an obligatory but permissive role in the development of the response.
      Column perfusion has proved to be a simple technique which can readily yield
      accurate data on responses of cells to stimulants and inhibitors.

PMID- 4374194
TI  - Increase in pituitary adenosine 3':5'-cyclic monophosphate content and
      potentiation of growth-hormone release from heifer anterior pituitary slices
      incubated in the presence of 3-isobutyl-1-methylxanthine.
AB  - The release of growth hormone from heifer anterior pituitary slices and the
      cyclic AMP content of the slices were increased by the phosphodiesterase
      inhibitor 3-isobutyl-1-methylxanthine, both increases being related to inhibitor
      concentration over the range 0.1-1.0mm. Neither Ba(2+) (6.9 or 2.3mm), K(+)
      (72mm), nor p-chloromercuribenzoate (20mum) had any effect on pituitary cyclic
      AMP content over a 20min period. 3-Isobutyl-1-methylxanthine potentiated the
      release of growth hormone in response to Ba(2+) (2.3mm) and K(+) (24mm), but the
      degree of potentiation did not depend on inhibitor concentration in the same way
      as did tissue cyclic AMP content. 3-Isobutyl-1-methylxanthine decreased the
      concentration of K(+) required to give maximum stimulation of growth-hormone
      release, but did not significantly increase the maximum response to Ba(2+).
      Growth-hormone release in the presence of prostaglandin E(2) (1mum) was increased
      by 3-isobutyl-1-methylxanthine and was inhibited by the prostaglandin antagonist,
      7-oxa-13-prostynoic acid, although this antagonist increased the pituitary cyclic
      AMP concentration and potentiated the prostaglandin E(2)-induced rise in cyclic
      AMP content. The stimulation of growth-hormone release by p-chloromercuribenzoate
      was not potentiated by 3-isobutyl-1-methylxanthine. The data suggest that Ba(+)
      and K(+) act at the same point in the secretory process as 3-isobutyl-1
      methylxanthine, although by a different mechanism, and that p
      chloromercuribenzoate has a different point of action.

PMID- 4374195
TI  - The role of adenosine 3':5'-cyclic monophosphate in the division of WI 38 cells.
      The cellular response to prostaglandin E1 and the effects of an cyclic adenosine
      3':5'-cyclic monophosphate analogue and prostaglandin E1 on cell division.
AB  - Inhibition of growth and DNA synthesis was observed in WI 38 cells incubated with
      8-methylthioadenosine 3':5'-cyclic monophosphate or prostaglandin E(1). The
      effect of both compounds on cell growth was reversible. On removal of these
      compounds from culture media the cells initiated DNA synthesis and divided. In
      addition, prostaglandin E(1) stimulated cyclic AMP formation in these cells to
      over 40 times the normal basal value. The increase in cyclic AMP concentration in
      WI 38 cells after addition of prostaglandin E(1) showed a marked variation. Cells
      that had recently been treated with trypsin and plated at a lower cell density
      exhibited a smaller response to addition of prostaglandin E(1) than cells that
      had divided and reached confluence.

PMID- 4374196
TI  - The action of local anaesthetics on lipolysis and on adenosine 3':5'-cyclic
      monophosphate content in isolated rat fat-cells.
AB  - 1. Local anaesthetics inhibited hormone-stimulated lipolysis in isolated rat fat
      cells. The most potent anaesthetic was dibucaine, which inhibited adrenaline
      stimulated lipolysis by 50% at a concentration of 0.16mm. 2. The amount of
      inhibition produced by a given concentration of anaesthetic was very similar with
      adrenaline, theophylline and dibutyryl cyclic AMP, at submaximal and maximal
      concentrations. 3. The inhibitory effect of dibucaine on lipolysis was apparent
      within 5 min and was constant over 1h. 4. Dibucaine inhibited basal, adrenaline
      stimulated and insulin-stimulated glucose uptake at concentrations 6-10-fold
      higher than those inhibiting lipolysis. 5. The effects of dibucaine on lipolysis
      and glucose uptake were reversed after removal of anaesthetic and washing of
      cells. 6. Dibucaine further elevated the concentration of cyclic AMP in the
      presence of adrenaline or adrenaline plus theophylline. 7. Dibucaine had no
      effect on ATP content at concentrations causing 80% inhibition of lipolysis, but
      lowered ATP content at higher concentrations. 8. The relative potency of
      different local anaesthetics as inhibitors of hormone-stimulated lipolysis
      paralleled their potency as inhibitors of ion movements in other systems. 9. The
      possibility is discussed that Ca(2+) ions are involved in the regulation of
      lipolysis, and that local anaesthetics inhibit lipolysis by interfering with
      Ca(2+) translocation.

PMID- 4374197
TI  - Changes in intramitochondrial adenine nucleotides in blowfly flight-muscle
      mitochondria.
AB  - 1. With freshly isolated blowfly mitochondria 38% of the intramitochondrial
      adenine nucleotide was present as AMP. 2. On incubation with oxidizable
      substrates the AMP and ADP concentrations fell and that of ATP rose; with
      pyruvate together with proline the ATP concentration reached its maximum value at
      6min; with glycerol phosphate the phosphorylation of endogenous nucleotide was
      more rapid. 3. Addition of the uncoupling agent carbonyl cyanide phenylhydrazone
      caused a rapid fall of ATP and a parallel rise in ADP, then ADP was converted
      into AMP. 4. This was in contrast with rat liver mitochondria endogenous AMP
      concentrations, which were always lower than those of blowfly mitochondria and
      changed little under different metabolic conditions. 5. Evidence is presented
      that adenylate kinase (EC 2.7.4.3) has a dual distribution in blowfly
      mitochondria, a part being located in the matrix space and a part in the space
      between the outer and inner mitochondrial membranes, as in liver and other
      mitochondria. 6. The possible regulatory role of changing AMP concentrations in
      the mitochondrial matrix was investigated. Partially purified pyruvate
      carboxylase (EC 6.4.1.1) and citrate synthase (EC 4.1.3.7) were inhibited 30% by
      2mm-AMP, whereas pyruvate dehydrogenase (EC 1.2.4.1) was unaffected. 7. AMP
      activated the NAD(+)-linked isocitrate dehydrogenase (EC 1.1.1.41) activity of
      blowfly mitochondria in the absence of ADP, but in the presence of ADP, AMP
      caused inhibition. 8. It is suggested that AMP may exert a controlling effect on
      the oxidative activity of blowfly mitochondria.

PMID- 4374198
TI  - Adaptive changes in the capacity of systems used for the synthesis of citrulline
      in rat liver mitochondria in response to high- and-low-protein diets.
AB  - 1. Citrulline synthesis was measured in mitochondria from rats fed on a standard
      diet, a high-protein diet, or on glucose. 2. With NH(4)Cl as the nitrogen source
      the rate of citrulline synthesis was higher in mitochondria from rats fed on a
      high-protein diet than in those from rats fed on a standard diet. When rats were
      fed solely on glucose the rate of synthesis of citrulline from NH(4)Cl was very
      low. 3. With glutamate as the nitrogen source the relative rates of citrulline
      synthesis were much lower than when NH(4)Cl was present, but similar adaptive
      changes occurred. 4. The activity of the mitochondrial glutamate-transporting
      system increased two to three times on feeding rats on a high-protein diet, but
      the K(m) for glutamate was unchanged. 5. Adaptive changes in certain
      intramitochondrial enzymes were also measured. 6. The results were interpreted to
      indicate that when an excess of substrate was present, citrulline synthesis from
      NH(4)Cl was rate-limited by the intramitochondrial concentration of N-acetyl
      glutamate, but citrulline synthesis from glutamate was rate-limited primarily by
      the activity of the glutamate-transporting system.

PMID- 4374199
TI  - The effects of potassium, 5-hydrocytryptamine, adrenocorticotrophin and
      angiotensin II on the concentration of adenosine 3':5'-cyclic monophosphate in
      suspensions of dispersed rat adrenal zona glomerulosa and zona fasciculata cells.
AB  - Dispersed rat adrenal cells prepared from both the capsule and the decapsulated
      gland were used to investigate the effects on cyclic AMP accumulation of known
      stimuli of steroidogenesis [ACTH (adrenocorticotrophin), angiotensin II, K(+)
      ions and 5-hydroxytryptamine]. Since glomerulosa-cell preparations from capsular
      strippings are normally contaminated with a proportion of fasciculata cells,
      cells purified by fractionation on a bovine serum albumin gradient were also
      used. The results showed that: (1) ACTH and angiotensin II stimulated cyclic AMP
      accumulation in both fractionated and unfractionated zona fasciculata cells; (2)
      5-hydroxytryptamine and an increased extracellular K(+) concentration (from 3.6
      to 8.4mm) had no effect on cyclic AMP concentrations in fasciculata cell
      preparations; (3) the addition of ACTH, angiotensin II, 5-hydroxytryptamine or
      K(+) to the incubation medium resulted in increased cyclic AMP concentrations in
      unpurified zona glomerulosa cell preparations; (4) fractionation and hence the
      virtual elimination of fasciculata contamination, did not affect the response to
      5-hydroxytryptamine and increased K(+) concentration. However, the responses to
      ACTH and angiotensin II were markedly lowered but not abolished. These results
      strongly suggest a link between cyclic AMP production and steroidogenesis in the
      zone of the adrenal gland that specifically secretes aldosterone. All four agents
      used stimulated both steroid output and cyclic AMP accumulation. However, at
      certain doses of 5-hydroxytryptamine, K(+) and angiotensin II the significant
      increases in corticosterone output were not accompanied by measurable increases
      in cyclic AMP accumulation.

PMID- 4374200
TI  - Synthesis of polyprenyltolouquinols from homogentisate and polyprenyl
      pyrophosphates in particulate fractions of Euglena and sugar beet.
AB  - Chloroplast-rich particles of sugar beet and Euglena gracilis are able to carry
      out the light-, H(2)O(2)- and O(2)-independent syntheses of a
      nonaprenyltoluquinol, an octaprenyltoluquinol and a phytyltoluquinol from
      homogentisate and nonaprenyl, octaprenyl and phytyl pyrophosphate. The formation
      of these compounds probably takes place by the concomitant polyprenylation (or
      phytylation) and non-oxidative decarboxylation of homogentisate.

PMID- 4374202
TI  - Isolation of the coat proteins of foot-and-mouth disease virus and analysis of
      the composition and N-terminal endgroups.

PMID- 4374201
TI  - Seven lysine isoaccepting tRNA's from polyoma virus-transformed cells.

PMID- 4374203
TI  - The immobilization of glucose oxidase via activation of its carbohydrate
      residues.

PMID- 4374204
TI  - Binding of 1-norepinephrine to isolated rat fat cell plasma membranes. Evidence
      against covalent binding and binding to catechol-O-methyl transferase.

PMID- 4374205
TI  - The utility of infrared spectroscopy as a probe of intact tissue:  determination
      of carbon monoxide and hemeproteins in blood and heart muscle.

PMID- 4374206
TI  - Heme complexes of rabbit hemopexin, human hemopexin and human serum albumin: 
      electron spin resonance and Mssbauer spectroscopic studies.

PMID- 4374207
TI  - Purification of exonuclease (phosphodiesterase) from the venom of Crotalus
      adamanteus.

PMID- 4374208
TI  - Phospholipid activation of Lactobacillus plantarum undecaprenyl pyrophosphate
      synthetase.

PMID- 4374209
TI  - Binding of 5S estradiol receptor to poly-deoxynucleotides.

PMID- 4374210
TI  - Stimulation of guanosine 3',5'-cyclic monophosphate accumulation in rat anterior
      pituitary gland in vitro by synthetic somatostatin.

PMID- 4374212
TI  - Enzyme activated anti-tumour agents. Conjugates of p-hydroxyaniline mustard as
      substrates for hydrolytic enzymes.

PMID- 4374214
TI  - Inhibition of DNA polymerases from RNA tumor viruses by tilorone and congeners:
      site of action.

PMID- 4374213
TI  - Inhibition of cell growth and of purine biosynthesis by allopurinol and 4
      aminopyrazolo(3,4-d)pyrimidine--a comparative study.

PMID- 4374216
TI  - Stimulated chloride transport by isolated parietal cells.

PMID- 4374215
TI  - Inhibition of platelet aggregation by 2-(p-chlorophenyl)-4-thiazoleacrylic acid
      (Wy-23,049)--comparison with acetylsalicylic acid.

PMID- 4374217
TI  - Effect of alphaxalone, a new intravenous anaesthetic, on oxidative
      phosphorylation in rabbit brain mitochondria.

PMID- 4374218
TI  - Further studies concerning the effects of clofibrate on respiration and oxidative
      phosphorylation of rat liver mitochondria.

PMID- 4374219
TI  - The effects of catecholamines upon the metabolism of foreign compounds and upon
      the distribution of perfusate in the isolated liver of the rat.

PMID- 4374221
TI  - [XVI National congress of physiological sciences, symposium: neural transmission
      and neural conduction].

PMID- 4374220
TI  - Inhibition of some rat hepatic microsomal enzymes by ethoxyquin.

PMID- 4374222
TI  - [Effect of gonadotropin releasing hormone on pituitary gonadotropin function in
      the presence of neoplasms of the pituitary gland].

PMID- 4374223
TI  - [Changes in the cortisol/cortisone ratio in humans caused by corticotropin
      stimulation].

PMID- 4374224
TI  - Usefulness and limitations of circumferential fibre shortening velocity in
      evaluating segmental disorders of left ventricular contraction.

PMID- 4374225
TI  - Occult carcinoma of the breast.

PMID- 4374227
TI  - Evaluation of host immunity in human neoplasia. II. Discussion.

PMID- 4374226
TI  - Cell mediated immunity to herpesvirus type 1 in carcinoma and pre-cancerous
      lesions.

PMID- 4374228
TI  - HL-A antigens and malignant disease.

PMID- 4374229
TI  - Immunological aspects of trophoblastic neoplasia.

PMID- 4374232
TI  - The management of the palatal pleomorphic adenoma.

PMID- 4374230
TI  - Immunity to tumours of the murine leukaemia-sarcoma virus complex.

PMID- 4374231
TI  - Significance of serum factors modifying cellular immune responses to growing
      tumours.

PMID- 4374233
TI  - An unusual presentation of rhabdomyosarcoma: a case report.

PMID- 4374234
TI  - Transport of nucleosides, nucleic acid bases, choline and glucose by animal cells
      in culture.

PMID- 4374235
TI  - Organisation of proteins in membranes with special reference to the cytochrome
      oxidase system.

PMID- 4374236
TI  - Cytochrome c binding to enzymes and membranes.

PMID- 4374237
TI  - The application of immobilized NAD+ in an enzyme electrode and in model enzyme
      reactors.

PMID- 4374239
TI  - Stereochemistry of the L-iditol dehydrogenase catalyzed hydrogen transfer to NAD.

PMID- 4374240
TI  - Hepatic sulfite oxidase. Effect of anions on interaction with cytochrome c.

PMID- 4374238
TI  - Acrylic copolymers as matrices for the immobilization of enzymes. II. The effect
      of a hydrophobic microenvironment on enzyme reactions studied with alcohol
      dehydrogenase immobilized to different acrylic copolymers.

PMID- 4374241
TI  - Hepatic sulfite oxidase. Identification of the molybdenum center as the site of
      irreversible inactivation by ferricyanide.

PMID- 4374242
TI  - Glycogen synthesis in mouse Ehrlich ascites carcinoma cells. The presence of an
      endogenous inhibitor for activation of glycogen synthase.

PMID- 4374243
TI  - Histone kinases and cyclic AMP-binding capacity of nuclei of human tonsillar
      lymphocytes.

PMID- 4374244
TI  - O-phosphoserine phosphatase from bovine brain and kidney. High molecular weight
      forms occurring during the purification.

PMID- 4374246
TI  - Inorganic pyrophosphatase in cultured cells.

PMID- 4374245
TI  - Studies on cyclic AMP phosphodiesterase in sea urchin eggs.

PMID- 4374247
TI  - Rat pancreas adenylate cyclase. II. Inactivation and protection of its hormone
      receptor sites.

PMID- 4374248
TI  - [Study of alpha-chymotrypsin using spin-labeled inhibitor].

PMID- 4374249
TI  - [Free radicals during photooxidation of amino acids and dipeptides sensitized by
      iron (III) complexes].

PMID- 4374250
TI  - [EPR study of the primary products of the photooxidation of chlorophyll a. Effect
      of water].

PMID- 4374251
TI  - [Formation of pigments of lipid nature in animal tissues during neoplastic growth
      and irradiation].

PMID- 4374252
TI  - [Vitamin E and free radical concentration in animal tissues].

PMID- 4374253
TI  - [EPR spectra of plant seeds].

PMID- 4374254
TI  - [Light-induced paramagnetic centers in photosystem II in chloroplasts and leaves
      of higher plants].

PMID- 4374255
TI  - [Nature of the free radical EPR signal recorded in dry animal tissues].

PMID- 4374256
TI  - [ERP study of the photochemical generation of chlorophyll and bacteriochlorophyll
      cation-radicals].

PMID- 4374258
TI  - [Possible mechanism for the intensification of glycolysis in the rat liver during
      carcinogenesis].

PMID- 4374257
TI  - [Makeup of the cytochromes of the bacteroid Rhizobium leguminosarum (Vicia
      faba)].

PMID- 4374259
TI  - [Hydrolysis of oligodesoxyribonucleotides by phosphohydrolases immobilized on
      cellulose].

PMID- 4374260
TI  - [Study of the phosphorylating activity of isolated nuclear membranes of the rat
      liver].

PMID- 4374261
TI  - Sleep and eye movement patterns in two groups of retardates.

PMID- 4374262
TI  - Intramitonchondrial crystalline inclusions in metastatic hypernephroma of the
      liver.

PMID- 4374263
TI  - Influence of glucagon on canalicular bile production in the dog.

PMID- 4374264
TI  - Nasopharyngeal carcinoma. VII. B and T lymphocytes in the circulating blood and
      in tumour tissue.

PMID- 4374265
TI  - Urinary cyclic AMP as an aid in the differential diagnosis of hypercalcemia.

PMID- 4374266
TI  - [Anti-synthetic beta-1-24 corticotropin antibodies].

PMID- 4374267
TI  - Evaluation of bilirubin derivatives for mass spectral analysis.

PMID- 4374268
TI  - Large scale enzymatic synthesis of nucleoside-5'-monophosphates using a
      phosphotransferase from carrots.

PMID- 4374269
TI  - [Effect of fentanyl on the activity of individual neurons of the bulbar
      respiration center].

PMID- 4374270
TI  - [State of the ultrastructure of the muscle cells of the hearts of rabbits
      following the effects of sanotensin].

PMID- 4374271
TI  - [Electron histochemical and biochemical study of glucose-6-phosphatase and beta
      glycerophosphatase activities in the nuclei of normal liver and hepatoma-27 in
      rats].

PMID- 4374272
TI  - Effect of shock following prolonged crushing of soft tissues on hypothalamic
      pituitary-adrenal function.

PMID- 4374273
TI  - Effect of sucrose on lipid metabolism in experimental animals and its relation to
      the fat content of their diet.

PMID- 4374274
TI  - Action of cardiac glycosides on the concentrations of adenyl nucleotides and
      nicotinamide-adenine dinucleotides in the rat myocardium.

PMID- 4374277
TI  - Ultrastructural localization of NAD-pyrophosphorylase in mouse liver nuclei.

PMID- 4374275
TI  - Intraendothelial inclusions in systemic lupus erythematosus.

PMID- 4374276
TI  - Effect of exogenous cytochrome C on oxidative phosphorylation in the liver of
      rats with acute toxic hepatitis.

PMID- 4374278
TI  - Electroendosmosis correction for electrophoretic mobility determined in cells.

PMID- 4374279
TI  - Rapid assays for adenylate cyclase and 3',5' cyclic AMP phosphodiesterase
      activities. Simultaneous measurements of other pathways of ATP catabolism.

PMID- 4374280
TI  - The use of 3-acetyl-pyridine adenine dinucleotide in the spectrophotometric assay
      of enzymatic activities coupled to dehydrogenases of unfavorable equilibrium.

PMID- 4374281
TI  - Thin layer gel filtration as a method for routine steroid receptor binding
      studies.

PMID- 4374282
TI  - In vivo preparation of (32P) adenosine 3',5'-cyclic monophosphate.

PMID- 4374283
TI  - A simple and highly sensitive method for sequence determination of 32P-labeled
      oligonucleotides.

PMID- 4374284
TI  - Effect of pharmacological blockade on lithium-induced water drinking.
AB  - Administration of lithium chloride (40 mg/kg i.p.) led to a significant increase
      in 24 h water intake of rats. Prior administration of propranolol and haloperidol
      blocked the effect of lithium while atropine failed to show such an effect. The
      dipsogenic effect of lithium is probably exerted through beta-adrenergic and
      dopaminergic pathways.

PMID- 4374285
TI  - Proceedings: Influence of postaglandins and oestrus cycle on the spasmodic action
      of angiotensin II and oxytocin on rat uterus.

PMID- 4374286
TI  - Proceedings: Oestradiol binding in neonatal rat brain cytosol.

PMID- 4374287
TI  - Proceedings: The effect of tetraethylammonium (TEA) on the anococcygeus muscle
      and on its response to motor and to inhibitory nerve stimulation.

PMID- 4374288
TI  - A study of the metabolic requirements for the contractile action of angiotensin
      upon guinea-pig ileum.
AB  - 1 Acetylcholine and angiotensin elicit a contraction of guinea-pig ileum. The
      metabolic requirements for these actions have been investigated.2 The angiotensin
      induced response was far more dependent upon the presence of glucose than was the
      response to acetylcholine.3 Anoxia and oxidative enzyme inhibition preferentially
      reduced the angiotensin-induced response.4 The significance of these results is
      discussed. It is concluded that the response to angiotensin is dependent upon an
      ATP source distinct from that required by the contractile process. It is further
      shown that this energy-dependent stage cannot be identified with the indirect,
      cholinergic component of the angiotensin response in this tissue.

PMID- 4374289
TI  - Long-term infusion of growth hormone release inhibiting hormone in acromegaly:
      effects on pituitary and pancreatic hormones.
AB  - Growth hormone release inhibiting hormone (GH-RIH) was infused at a rate of 1.3
      mug/min for 28 hours into four patients with acromegaly, two of whom also had
      clinical diabetes mellitus. Growth hormone and glucagon were suppressed
      throughout the infusion though delayed secretion of insulin occurred in
      association with both meals and an oral glucose load. Glucose tolerance was
      improved in one diabetic patient who was taking chlorpropamide while the other
      required much less insulin than usual. Secretion of endogenous thyroid
      stimulating hormone was lowered in one euthyroid patient on carbimazole.
      Luteinizing hormone, follicle-stimulating hormone, ACTH, and prolactin were not
      affected. Serum somatomedin levels were reduced in one patient. There was a rapid
      rebound of all the suppressed hormones when the infusions stopped. Longer-acting
      analogues of GH-RIH will be needed before long-term therapy of acromegaly or
      diabetes mellitus becomes possible, but such preparations should be available
      soon for clinical trial.

PMID- 4374290
TI  - Blood and neoplastic diseases. Management of solid tumours-surgery, radiotherapy,
      and chemotherapy.

PMID- 4374291
TI  - Letter: neuropathy due to cytosine arabinoside.

PMID- 4374293
TI  - Food intake and amphetamine anorexia after selective forebrain norepinephrine
      loss.

PMID- 4374294
TI  - Changes in the activity of respiratory neurons during sleep.

PMID- 4374292
TI  - Blood and neoplastic diseases. Solid tumours in children.

PMID- 4374295
TI  - Multiple sites of spike initiation in a single dendritic system.

PMID- 4374296
TI  - The effect of diethyl ester L-glutamate on evoked excitatory junction potentials
      at the crustacean neuromuscular junction.

PMID- 4374297
TI  - 5-Hydroxydopamine 'tagged' neuronal boutons in rabbit neostriatum:
      interrelationship between vesicles and axonal membrane.

PMID- 4374298
TI  - The origin of the dopamine nerve terminals in limbic and frontal cortex. Evidence
      for meso-cortico dopamine neurons.

PMID- 4374299
TI  - [Comparison of macro- and micromethod for plasma renin aktivity determination in
      man (author's transl)].

PMID- 4374300
TI  - [Diagnosis and prognosis of scirrhous carcinoma of stomach].

PMID- 4374301
TI  - [Pluriglandular adenomatosis. Case contribution on the clinical picture and
      pathology].

PMID- 4374302
TI  - The reliability of selective media for the enumeration of unheated and heated
      staphylococci.

PMID- 4374303
TI  - Does hypolipidemic therapy prevent coronary heart disease?

PMID- 4374304
TI  - Ultrastructural studies on the development of the nerve supply in the rabbit pars
      intermedia.

PMID- 4374305
TI  - The ultrastructure of the human fetal pineal gland. I. Cell types and blood
      vessels.

PMID- 4374306
TI  - Morphometric analysis of the midgut of female Aedes aegypti (L.) (Insecta,
      Diptera) under various physiological conditions.

PMID- 4374308
TI  - Catalase-like crystals in parathyroid gland cells of Rana temporaria L.

PMID- 4374307
TI  - Ovulation and the mechanism of follicle rupture. IV. Ultrastructure of membrana
      granulosa of rabbit graafian follicles prior to induced ovulation.

PMID- 4374309
TI  - Effects of ACTH on organelle interrelationships in the corpus luteum of the
      pregnant deermouse.

PMID- 4374311
TI  - Cytologic observations on the secretory cells of the chin (submandibular) gland
      and brown inguinal gland in the rabbit.

PMID- 4374310
TI  - The fine structure of prostomial photoreceptors in Eulalia viridis (Polychaeta;
      Annelida).

PMID- 4374313
TI  - An ultrastructural and electrophysiological study of the development of neuro
      muscular junctions between previously dissociated foetal rat cells in vitro.

PMID- 4374312
TI  - Primary tissue culture of human adult adrencortical cells. Methodology and
      electron microscopic observations on ACTH-deprived and ACTH-treated cortical
      cells.

PMID- 4374314
TI  - In vitro synthesis of methylated messenger RNA by the virion-associated RNA
      polymerase of vesicular stomatitis virus.

PMID- 4374315
TI  - Alterations leading to increased ribonucleotide reductase in cells selected for
      resistance to deoxynucleosides.

PMID- 4374317
TI  - [Study on the kind of spreading, reproduction and persistence of Herpes simplex
      virus and its importance for clinical practice].

PMID- 4374319
TI  - Increased urinary excretion of pyrimidine and nicotinamide derivatives in rats
      treated with methyl methanesulphonate.

PMID- 4374318
TI  - Repair replication of opossum lymphocyte DNA: effect of compounds that bind to
      DNA.

PMID- 4374316
TI  - The effect of cyclic nucleotides on purine biosynthesis and the induction of PRPP
      synthetase during lymphocyte activation.

PMID- 4374320
TI  - Specificity and inhibition of an amylase present in the testicular tissue of the
      rat.

PMID- 4374321
TI  - Evaluation of the precipitation-in-gel reaction in the diagnosis of smallpox.
AB  - Specimens of vesicular or pustular fluids and of scabs from patients with
      smallpox as well as emulsions of variola-infected chorioallantoic membrane (CAM)
      were tested for virus titres and by the precipitation-in-gel (PIG) reaction. They
      were also tested after exposing them directly to sunlight and after keeping them
      at temperatures of -20 degrees C, 4 degrees C, and 25 degrees C. It was found
      that when extracts of fresh specimens were diluted to the point where the PIG
      reaction became negative there was still a titre of 10(4)-10(5) infectivity in
      the swab extracts and 10(3)-10(4) infectivity in the scab extracts. It was also
      found that the PIG reactions were all negative on specimens that were kept for 14
      days at 25 degrees C, and that several were negative after only 7 days; the loss
      in infectivity titre, however, was only slight in all the specimens tested. It is
      concluded that the laboratory diagnosis of smallpox by virus inoculation of CAM
      is more reliable than by the PIG test.

PMID- 4374322
TI  - Transmission of the virus of foot and mouth disease between animals and man.
AB  - The virus of foot and mouth disease causes severe epizootics in animals and
      infrequently evokes painful, but transient, clinical signs in man. Adults in
      certain occupational groups and young children are particularly exposed to risk.
      Infected persons may disseminate virus for up to about 14 days. The virus can be
      transmitted from animals to animals, from animals to man, from man to animals
      and, probably, from man to man. Evidence for transfer of the disease between
      human and animal populations is reviewed in detail and modern methods of
      diagnosis are described. Predisposing factors play an important role in the
      development of overt foot and mouth disease in man. Subclinical infection occurs.
      The possibility of aerial transfer of the virus between man and domestic
      livestock constitutes a hazard, especially to the latter. Attention is directed
      to the need for sophisticated diagnostic techniques, to requirements for adequate
      precautions in the handling and disposal of affected animals, and to hygienic
      measures for disease control.

PMID- 4374323
TI  - [Amino acid sequences of a peptide obtained by cyanogen bromide chemical
      fractionation of lobster (Homarus vulgaris) arginine-kinase].

PMID- 4374324
TI  - [Lowering of calcium absorption under the effects of several alkaline
      phosphomonoesterase inhibitors].

PMID- 4374325
TI  - [Rapid technic of isolation and monolayer survival of adult rat hepatocytes].

PMID- 4374326
TI  - ["Black box" model for the histology of spherical structures].

PMID- 4374327
TI  - [Demonstration of specific receptors sites for 3,5,3'triiodo-L-thyronine on blood
      lymphocytes in rats].

PMID- 4374328
TI  - [Autoradiographic localization of catecholamine fixing cells in rat and man].

PMID- 4374329
TI  - [Demonstration of homology between a murine oncornavirus genome and RNA rich in
      poly-adenylates from human leukemia cells].

PMID- 4374330
TI  - [Study of a parasite of the digestive gland observed during the current epizootic
      of the flat oyster].

PMID- 4374331
TI  - Rehabilitation of the cancer patient: its role in the scheme of comprehensive
      care.

PMID- 4374332
TI  - Editorial: the current status of feline leukemia virus research.

PMID- 4374333
TI  - Simple siliceous pneumoconiosis of Bedouin females in the Negev desert.

PMID- 4374336
TI  - Computer programs for ESR spectral analysis.

PMID- 4374334
TI  - Determination of drugs in biologic specimens--a review.

PMID- 4374337
TI  - Adrenal function in patients receiving medroxyprogesterone acetate.

PMID- 4374338
TI  - Investigations on the use of testosterone oenanthate as a male contraceptive
      agent.

PMID- 4374340
TI  - Histopathology and histochemistry of the insects treated with chemosterilants. V.
      Nucleic acids, phospholipids and phosphatases in the female reproductive organs
      of chemosterilized Poecilocerus pictus.

PMID- 4374339
TI  - Ligand-induced oligomerization and regulatory mechanism.

PMID- 4374342
TI  - [Tumors and tumor-like lesions of the hand].

PMID- 4374341
TI  - Antiviral 1,3,4-thiadiazoles. I. Action on multiplication of Mengo Virus in FL
      cells.

PMID- 4374343
TI  - [Clinical picture, disease course and prognosis of malignant synovialomas].

PMID- 4374344
TI  - [The midwife and health education].

PMID- 4374345
TI  - [Stability of cytoplasmic poly-(A)-containing RNAs in cells infected with
      encephalomyocarditis virus].

PMID- 4374346
TI  - [Quaternary structure of NAD-kinase of rabbit skeletal muscles].

PMID- 4374347
TI  - [Intensive care of intoxication. Patient material from the intensive care unit of
      Tampere central hospital 1970-71].

PMID- 4374348
TI  - [Extracranial metastasis of glioblastoma multiforme in a child].

PMID- 4374349
TI  - [The effect of unithiol (2-mercapto-propane sulfonate sodium) on the motor
      activity stimulated by amphetamine, on evipan anesthesia and on the activity of
      dopamine-beta-hydroxylase].

PMID- 4374352
TI  - Molecular morphology of ribosomes. Structural considerations of Escherichia coli
      ribosomal subunits utilizing lactoperoxidase-catalyzed iodination of ribosomal
      proteins.

PMID- 4374350
TI  - New data on three types of anahormones (anahormones of LH, GH, ACTH, lipotropin,
      calcitonin and parathyroid hormone).

PMID- 4374351
TI  - Phospholipid metabolism in embryonic rat fibroblasts following stimulation by a
      combination of the serum proteins S1 and S2.

PMID- 4374353
TI  - Nitrate reductase as a product-inducible enzyme.

PMID- 4374354
TI  - On the structure of phenylalanine tRNA from yeast. Spin-label studies.

PMID- 4374355
TI  - Precursors of cytochrome oxidase in cytochrome-oxidase-deficient cells of
      Neurospora crassa. Comparison of the nuclear mutant cni-1, the cytoplasmic mutant
      mi-1, and copper-depleted wild type.

PMID- 4374356
TI  - Dose-limiting tissues in relation to types and location of tumours: implications
      for efforts to improve radiation dose distributions.

PMID- 4374358
TI  - Biological properties of a C-type leuko-virus isolated from mouse myeloma cells.

PMID- 4374357
TI  - Comparative toxicity on leukocytes and platelets of two regimens of CCNU: the
      relationship between maximum dose and optimum dose.

PMID- 4374359
TI  - The influence of body weight and cell size on lipogenesis and lipolysis of
      isolated rat fat cells.

PMID- 4374360
TI  - Hypertriglyceridaemia secondary to liver disease.

PMID- 4374361
TI  - Effects of papaverine on the rabbit ileum under the influence of altered
      temperature and extracellular Ca2+.

PMID- 4374362
TI  - [Induction of Mycobacterium infection by introduction of the organisms into the
      lung through an intratracheal vinyl tube].

PMID- 4374363
TI  - The contribution of adherent films of liquid on the cut surfaces of mouse brain
      slices to tissue water and "extracellular" marker space.

PMID- 4374364
TI  - An intracellular analysis of visual cortical neurones to moving stimuli: response
      in a co-operative neuronal network.

PMID- 4374365
TI  - Post-tetanic effect on dorsal root reflex and flexor reflex in the forelimb of
      cats.

PMID- 4374366
TI  - Responses of interpositus neurones to inputs from muscle receptors.

PMID- 4374369
TI  - Function Organization of primate oculomotor system revealed by cerebellectomy.

PMID- 4374367
TI  - Electrophysiological properties of lateral reticular nucleus cells: I. Antidromic
      activation.

PMID- 4374368
TI  - Electrophysiological properties of lateral reticular nucleus cells: II. Synaptic
      activation.

PMID- 4374370
TI  - The lateral reticular nucleus in the cat. I. Mossy fibre distribution in
      cerebellar cortex.

PMID- 4374372
TI  - [Quantitative histometric investigations on paw edema induced by carrageenin,
      formalin and aerosil in rats (author's transl)].

PMID- 4374371
TI  - The lateral reticular nucleus in the cat. II. Organization of component activated
      from bilateral ventral flexor reflex tract (bVFRT).

PMID- 4374373
TI  - Ultrahistochemical demonstration of periodate reactive and alpha-amino groups in
      experimental amyloid.

PMID- 4374374
TI  - Paradoxical sleep and avoidance learning of Swiss white mice after early
      undernutrition by raising in large litters.

PMID- 4374375
TI  - The effect of reserpine and chlorimipramine on glycogen content in different
      brain structures of rat.

PMID- 4374376
TI  - Preliminary note on the occurrence of a biological compound showing fluorescence
      characteristics similar to that of NADH.

PMID- 4374377
TI  - A convenient colourimetric method for routine assay of brain adenylate cyclase.

PMID- 4374378
TI  - Mechanism of rearrangement of penicillin V (S)-sulfoxide into delta-2 and delta-3
      cephem compounds.

PMID- 4374379
TI  - [Antiviral chemotherapeutic agents. XVII. Potential interferon inducers:
      adamantane derivatives].

PMID- 4374380
TI  - [Synthesis, biological activity, resistance to acids and penicillinase of some
      gamma-pyronpenicillins].

PMID- 4374381
TI  - Determination of the oxidation-reduction potential of the bound iron-sulphur
      proteins of the primary electron acceptor complex of photosystem I in spinach
      chloroplasts.

PMID- 4374382
TI  - 2,3-Diphosphoglycerate synthesis by human white ghosts.

PMID- 4374383
TI  - Sequence analysis of the 3'-T1 oligonucleotide of 16S ribosomal RNA from
      Escherichia coli.

PMID- 4374384
TI  - Glutamine phosphoribosylpyrophosphate amidotransferase: increased activity in
      hepatomas.

PMID- 4374386
TI  - Effects of hormones on cyclic AMP release from rat adipose tissue in vitro.

PMID- 4374385
TI  - Isolation of the regulatory subunit of pig-brain histone kinase by affinity
      chromatography on cyclic-AMP-containing adsorbent.

PMID- 4374387
TI  - Inhibition of protein synthesis in tendon cells by extracts from experimental
      granulation tissue.

PMID- 4374388
TI  - Periplasmic CO-binding c-type cytochrome in a marine bacterium.

PMID- 4374389
TI  - Consequences of the intracellular distribution of cyclic 3',5'-nucleotides
      phosphodiesterases.

PMID- 4374391
TI  - Neurophysin methylation in extracts of bovine posterior pituitary gland: hormone
      binding ability.

PMID- 4374390
TI  - Effect of ionophore A23187 on thyroid secretion.

PMID- 4374392
TI  - Rapid, light-induced changes of retinal cyclic GMP levels.

PMID- 4374393
TI  - Inhibition of mitochondrial malate dehydrogenase by 2-thenoyltrifluoroacetone.

PMID- 4374394
TI  - Phosphorylation of protein components of isolated zymogen granule membranes from
      the rat pancreas.

PMID- 4374395
TI  - Two precursor 5S RNA species in Bacillus licheniformis: characterization and
      partial analysis of primary structure.

PMID- 4374396
TI  - Presence of a cyclic-AMP-binding protein in Jerusalem artichoke rhizome tissues.

PMID- 4374397
TI  - Chloroplast and non-chloroplast adenosine-3':5'-cyclic-monophosphate-receptor
      proteins in Euglena gracilis.

PMID- 4374399
TI  - Interaction of Chinese hamster embryonic cells with the helper-dependent Rous
      sarcoma virus.

PMID- 4374398
TI  - Morphine antagonizes the action of prostaglandin in neuroblastoma cells but not
      of prostaglandin and noradrenaline in glioma and glioma times fibroblast hybrid
      cells.

PMID- 4374400
TI  - Significance of acid amyloglucosidase in sulphonylurea-induced insulin release.

PMID- 4374401
TI  - Effect of cholera toxin on insulin release in monolayer cultures of the endocrine
      pancreas.

PMID- 4374403
TI  - Chemical and enzymatic changes in microsomes of chicken livers following
      stimulation by oestrogens.

PMID- 4374402
TI  - Hormone-induced maturation of Xenopus laevis oocytes: effects of different
      steroids and study of the properties of a progesterone receptor.

PMID- 4374404
TI  - Mechanism of actinomycin resistance in SV40-transformed hamster cells.

PMID- 4374406
TI  - Abnormal regulation of cyclic AMP phosphodiesterase: a hypothesis for the
      development of cancer of nerve cells.

PMID- 4374405
TI  - Cyclic AMP-elevating agents inhibit proliferation of keratinizing guinea pig
      epidermal cells.

PMID- 4374407
TI  - Intercellular interactions in eukaryotic homeostasis.

PMID- 4374408
TI  - Mono- and triphosphate nucleotides, adenylatecyclase and phosphodiesterase
      activities in the intestine of normal or prolactin-treated Bufo bufo larvae.

PMID- 4374409
TI  - Studies of metabolism in embryonic development. VI. Cortisol-binding proteins of
      trout embryos.

PMID- 4374410
TI  - Misrepair mutagenesis in bacteriophage T4.
AB  - The T4 mutations px, y and 1206 inactivate an error-prone recombination-like
      repair system, reducing or abolishing mutagenesis by UV irradiation, MMS, and
      white light irradiation in the presence of the photosensitizer 8MOP. Both px and
      y increase some spontaneous mutation rates and slightly enhance proflavin
      mutagenesis; neither mutation affects thymineless or 2AP mutagenesis appreciably,
      but both mildly enhance 5BU mutagenesis. The mutation hm promotes UV, MMS,
      photodynamic, thymineless, and base analog mutagenesis, in addition to
      spontaneous base pair substitution mutation. It does not, however, markedly
      affect proflavin mutagenesis. The px mutation maps in the vicinity of genes 41
      56, and the hm mutation maps in the vicinity of genes rI-v.

PMID- 4374411
TI  - Variation of mutagenic action on nonsense mutants at different sites in the iso-1
      cytochrome c gene of yeast.
AB  - Three ochre and two amber mutants in yeast have been definitively identified by
      the amino acid replacements in iso-1-cytochromes c from intragenic revertants.
      Except for rare and sometimes unusual changes, all of the replacements were
      single amino acids whose codons differed from UAA or UAG by one base. These
      assignments, which were based on the absence of tryptophan replacements in ochre
      revertants, could be corroborated from the studies of two groups of suppressors
      that were shown to act on either the ochre or amber mutants. All five nonsense
      mutants are located at different sites in the cyc1 gene and all are at sites that
      can be occupied by amino acids having a wide range of structures. The relative
      frequencies of the amino acid replacements indicate that identical codons located
      at different sites may respond differently to a mutagenic agent. Notably
      glutamine replacements occurred almost exclusively in UV-induced revertants of
      only one ochre mutant cyc1-9, but not at all or at reduced proportions in the
      others. Similarly, lysine replacements occurred almost exclusively in the NA
      induced revertants of only the ochre mutant cyc1-72, but not at all in the
      others. These and other results reveal that mutation of A.T base pairs by UV and
      nitrous acid are dependent upon the location of the codon within the gene as well
      as the location of the base pair within the codon. From these findings, it
      appears as if the type of base-pair changes induced by UV and nitrous acid are
      strongly influenced by adjacent nucleotide sequences.

PMID- 4374412
TI  - [Neurological complications of Sjogren's syndrome].

PMID- 4374413
TI  - Histochemical study of traumatized muscle.

PMID- 4374415
TI  - Gelatinous adenocarcinoma of the renal pelvis.

PMID- 4374414
TI  - Histoenzymological observations of the response to injury and regeneration of the
      frog myocardium.

PMID- 4374417
TI  - Educating for discharge planning.

PMID- 4374416
TI  - Carcinogenicity of synthetic aflatoxin M1 in rats.

PMID- 4374418
TI  - Hereditary malignant hyperpyrexia associated with muscle adenylate kinase
      deficiency.

PMID- 4374419
TI  - Osteo-onychodysostosis: a new family.

PMID- 4374420
TI  - Nephroblastoma in adult--a case report.

PMID- 4374422
TI  - Biological and biochemical studies on thioacetamide induced hepatocarcinogenesis.

PMID- 4374423
TI  - Soft tissue tumours. I. Benign tumours.

PMID- 4374421
TI  - Uncommon polypoid tumours of nasal cavity.

PMID- 4374424
TI  - Soft tissue tumours. 2. Malignant tumours.

PMID- 4374425
TI  - Malignant granular cell myoblastoma--report of a case.

PMID- 4374426
TI  - Fatty acid composition of phospholipids and the phosphatidyl inositomannoside
      antigens of mycobacteria.

PMID- 4374427
TI  - Contribution on the clinical aspects and therapy of bronchial adenoma.

PMID- 4374428
TI  - Serial study of plasma angiotensin, electrolytes and juxta-glomerular index in
      experimental renal hypertension of monkeys.

PMID- 4374429
TI  - Cytomegalovirus infection in Pondicherry (South India)--a serological survey.

PMID- 4374430
TI  - evaluation of egg inoculation and precipitation in gel test for laboratory
      diagnosis of smallpox.

PMID- 4374432
TI  - Agar gel-diffusion test with the sera of rabbits and monkeys inoculated with
      different strains of vaccinia virus.

PMID- 4374431
TI  - Adreno-cortical function tests in lepra reaction.

PMID- 4374433
TI  - Clostridium perfringens in hospital patients.

PMID- 4374434
TI  - Primary bladder stone disease in children--crystallisation studies with special
      reference to urinary excretion of pyrophosphates.

PMID- 4374435
TI  - Hyperlipoproteinemia type V (a case report).

PMID- 4374436
TI  - [A new approach in the treatment of pain, an implanted spinal cord stimulator].

PMID- 4374437
TI  - 113Sn/113Inm radioisotope generator systems.

PMID- 4374438
TI  - A neuron model for simulation of frequency response characteristics.

PMID- 4374439
TI  - Metronidazole ('Flagyl'): a pulse radiolysis and e.s.r. study.

PMID- 4374440
TI  - Multiplicity reactivation of human cytomegalovirus inactivated by ultra-violet
      light.

PMID- 4374441
TI  - Radicals in irradiated monocrystals of the base-pair complex 9-ethyl adenine: 1
      methyl uracil.

PMID- 4374442
TI  - Some biochemical effects of ethanol on CNS.

PMID- 4374444
TI  - Community psychiatric nursing in Britain: an historical review.

PMID- 4374443
TI  - Alcohol and nervous system with special reference to the enolic neuropathies.

PMID- 4374446
TI  - Enhanced replication of temperature-sensitive mutants of herpes simplex virus
      type 2 (HSV-2) at the nonpermissive temperature in cells transformed by HSV-2.

PMID- 4374445
TI  - RNA polymerase activity and inhibition in herpesvirus-infected cells.

PMID- 4374447
TI  - A compendium of herpesviruses isolated from non-human primates.

PMID- 4374448
TI  - On a new inhibition of poliovirus RNA replication.

PMID- 4374449
TI  - Prevalence of endogenous oncornavirus in guinea pigs.

PMID- 4374450
TI  - Landre-Guillain-Barre syndrome associated with recent herpes virus hominis
      infection.

PMID- 4374451
TI  - Thyroid lymphography.

PMID- 4374452
TI  - Characterization of NAD glycohydrolase from lymph duct lymphocytes.

PMID- 4374453
TI  - Proceedings: Structural modifications of fructose 1,6-bisphosphatase and its
      regulation by histidine under gluconeogenic conditions.

PMID- 4374454
TI  - Proceedings: Metabolism of carbamyl phosphate in donkey liver.

PMID- 4374455
TI  - Successive overlapping outbreaks of febrile pharyngitis and pharyngoconjunctival
      fever associated with adenovirus types 2 and 7, in a Kibbutz.

PMID- 4374456
TI  - Lipase activities in the lungs of rats subjected to experimental
      hypertriglyceridemia and fat embolism.

PMID- 4374458
TI  - Feline leukemia virus and public health awareness.

PMID- 4374457
TI  - [Localization of biogenic amines in the rat spinal cord. A fluorescence
      histochemical study after intraventricular injection of L-dopa (author's
      transl)].

PMID- 4374460
TI  - Erythrocyte glucose-6-phosphate dehydrogenase deficiency in diabetes (maturity
      onset).

PMID- 4374461
TI  - Chloramphenicol--induced peripheral neuropathy (a case report).

PMID- 4374459
TI  - The modulation of sensory input and motor output in autistic children.

PMID- 4374462
TI  - Hepatic lymphography in cirrhosis of the liver.

PMID- 4374463
TI  - [Soft tissue of the hand and fingers].

PMID- 4374465
TI  - Use of mannitol as an internal standard in the gas-liquid chromatography of
      methyl glycosides.

PMID- 4374464
TI  - Skeletal immaturity in psychiatrically disturbed adolescents.

PMID- 4374467
TI  - New solvent systems for the separation of free and conjugated bile acids.

PMID- 4374466
TI  - Gas chromatographic analysis of the Alternaria metabolite, tenuazonic acid.

PMID- 4374468
TI  - [Quantitative analysis of barbiturates by thin-layer chromatography].

PMID- 4374469
TI  - Thin-layer chromatographic study of isoquinoline alkaloids with BN-CHAMBER.

PMID- 4374470
TI  - Childhood acute lymphoblastic leukemia. a survey of children treated between 1963
      and 1972 at Children's Memorial Hospital, Chicago.

PMID- 4374471
TI  - The nature of emergency room follow-up care.

PMID- 4374472
TI  - Exaggerated response to levodopa. A case of "contaminated parkinsonism".

PMID- 4374473
TI  - Significance of the Apgar score in the evaluation of mental retardation.

PMID- 4374474
TI  - Periodate-lysine-paraformaldehyde fixative. A new fixation for immunoelectron
      microscopy.

PMID- 4374475
TI  - Comparison of the effects of enterotoxins of Shigella dysenteriae and Vibrio
      cholerae on the adenylate cyclase system of the rabbit intestine.

PMID- 4374476
TI  - Modification of human neutrophil response to endotoxin with polymyxin B sulfate.

PMID- 4374478
TI  - [Clostridium perfringens. (3). Its distribution in food and serotypes].

PMID- 4374477
TI  - Fecal Clostridium perfringens and rheumatoid arthritis.

PMID- 4374479
TI  - Indication and technique for the reconstruction of nerve defects in head and
      neck.

PMID- 4374480
TI  - Proceedings: Control of steroidogenesis in adrenal tissue from the developing
      opossum, Didelphis marsupialis virginiana.

PMID- 4374481
TI  - Proceedings: Differences between the patterns of corticotrophin and luteinizing
      hormone release by perifused rat pituitaries in response to hypophysiotropic
      substances.

PMID- 4374482
TI  - Proceedings: In-vitro release of corticotrophin by the pars intermedia of the
      rainbow trout pituitary.

PMID- 4374483
TI  - The breast cancer discriminant: effect of age, obesity, hirsutism, starvation,
      and changes in adrenocortical and gonadal activity.

PMID- 4374484
TI  - Nuclear and cytoplasmic oestrogen receptors in vaginal and uterine tissue of mice
      treated neonatally with steroids and prolactin.

PMID- 4374485
TI  - Proceedings: The development of radioimmunoassays for 18-hydroxycorticosterone
      and 18-hydroxy-11-deoxycorticosterone.

PMID- 4374486
TI  - Diurnal changes in plasma testosterone and studies on plasma corticosteroids in
      non-anaesthetized male rhesus monkeys (Macaca mulatta).

PMID- 4374487
TI  - Release of 131I from the ovary of the laying Japanese quail after injection of
      perchlorate, thiocyanate or iodide.

PMID- 4374488
TI  - Plasma concentrations of cortisol in hypophysectomized and sodium chloride
      adapted goldfish (Carassius auratus L.).

PMID- 4374489
TI  - The non-electrogenic nature of angiotensin-stimulated sodium transport.

PMID- 4374491
TI  - Proceedings: Evidence for a specific oestradiol-binding protein in neonatal rat
      brain.

PMID- 4374492
TI  - Proceedings: The relationship between oestradiol-17beta receptor concentration
      and endogenous oestradiol-17beta in human breast tumour tissue.

PMID- 4374490
TI  - Proceedings: Familial glucocorticoid deficiency.

PMID- 4374493
TI  - Proceedings: Human placental oestradiol-17beta dehydrogenase affinity labelled at
      the active region.

PMID- 4374495
TI  - Proceedings: The thyroid-stimulating hormone receptor and thyroid-stimulating
      antibodies.

PMID- 4374494
TI  - Proceedings: Factors influencing the stimulation of prostatic RNA polymerase by
      5alpha-dihydrotestosterone-receptor complexes.

PMID- 4374496
TI  - Pharmacological studies on a locust neuromuscular preparation.

PMID- 4374497
TI  - The possible involvement of brain microtubules in memory fixation.

PMID- 4374498
TI  - Pharmacological induction of plasticization in the abdominal cuticle of Rhodnius.

PMID- 4374499
TI  - Estimation of age from skeletal remains.

PMID- 4374500
TI  - Equilibrium potential for the postsynaptic response in the squid giant synapse.
AB  - The reversal potential for the EPSP in the squid giant synapse has been studied
      by means of an intracellular, double oil gap technique. This method allows the
      electrical isolation of a portion of the axon from the rest of the fiber and
      generates a quasi-isopotential segment. In order to make the input resistance of
      this nerve segment as constant as possible, the electroresponsive properties of
      the nerve membrane were blocked by intracellular injection of tetraethylammonium
      (TEA) and local extracellular application of tetrodotoxin (TTX). Thus, EPSP's
      could be evoked in the isolated segment with a minimal amount of
      electroresponsive properties. The reversal potential for the EPSP (EEPSP) was
      measured by recording the synaptic potential or the synaptic current during
      voltage clamping. The results indicate that EEPSP may vary from +15 to +25 mV,
      which is more positive than would be expected for a 1:1 conductance change for
      Na(+) and K(+) (approximately -15 mV) and too negative for a pure Na(+)
      conductance ((+)40 mV). This latter value (E(Na)) was directly determined in the
      voltage clamp experiments. The results suggest that the synaptic potential is
      probably produced by a permeability change to Na(+) to K(+) in a 4:1 ratio. No
      change in time-course was observed in the synaptic current at clamp levels of 
      100 and +90 mV. The implications of a variable ratio for Na(+)-K(+) permeability
      in subsynaptic-postsynaptic membranes are discussed.

PMID- 4374501
TI  - Adenovirus antigens: a model system in mice for subunit vaccination.

PMID- 4374502
TI  - Mechanism of interferon induction by NDV: A MONOLAYER AND SINGLE CELL STUDY.

PMID- 4374503
TI  - Lysosomal enzyme activity in poliovirus-infected HeLa cells and vesicular
      stomatitis virus-infected L cells: biochemical and histochemical comparative
      analysis with computer-aided techniques.

PMID- 4374504
TI  - Isolation and preliminary characterization of temperature-sensitive mutants of
      Sindbis virus strain AR339.

PMID- 4374505
TI  - Artificial assembly of envelope particles of HVJ (Sendai virus). Fusion activity
      of envelope particles.

PMID- 4374506
TI  - Herpes simplex virus-induced enhancement of mitochondrial DNA synthesis in the
      absence of virus replication.

PMID- 4374507
TI  - The cerebellum in mucopolysaccharidosis. A histological, histochemical, and
      ultrastructural study.
AB  - Studies in the morphology, histochemistry, and ultrastructure of the cerebellum,
      with special reference to the Purkinje cell dendrites, have been undertaken in
      eight cases of gargoylism. The results suggest that the demonstration of ovoid
      swellings of the Purkinje cell dendrites by the Cajal method for the cerebellum,
      together with certain histochemical findings, may enable a diagnosis of
      mucopolysaccharidosis to be made. Possible mechanisms for the formation of these
      swellings are briefly discussed.

PMID- 4374508
TI  - Anterior interosseous nerve palsy: spontaneous recovery in two patients.
AB  - The case histories of two patients who developed an anterior interosseous nerve
      palsy apparently as a result of an external pressure injury are reported. Both
      patients recovered fully without surgical exploration, one 19 months and the
      other nine months after the onset. It is stressed that complete recovery may
      occur spontaneously.

PMID- 4374510
TI  - Toxic polyneuropathy due to glue-sniffing. Report of two cases with a light and
      electron-microscopic study of the peripheral nerves and muscles.

PMID- 4374509
TI  - Encephalitis associated with carcinoma. Central hypoventilation syndrome and
      cytoplasmic inclusion bodies.
AB  - A case of encephalitis associated with a remote and occult oat cell carcinoma is
      presented in which the main clinical features were progressive dementia and
      central hypoventilation syndrome. The only significant anatomical lesions within
      the known anatomical substrate of respiration affected the locus caeruleus on
      both sides. It is speculated that the degeneration of the locus caeruleus was
      responsible for the central hypoventilation syndrome. Hitherto undescribed
      neuronal intracytoplasmic eosinophilic inclusions were found in an isolated
      lesion of the insular cortex. Electron microscopy failed to disclose viral
      particles in the regions of neuronal degeneration.

PMID- 4374511
TI  - GM1 gangliosidosis.

PMID- 4374512
TI  - Ultrastructural changes of muscle in malignant hyperthermia.

PMID- 4374513
TI  - Oculopharyngeal muscular dystrophy. A case with abnormal mitochondria and
      "fingerprint" inclusions.

PMID- 4374514
TI  - Ultrastructural demonstration of neuronal storage in fetal Tay-Sachs disease.

PMID- 4374515
TI  - Biochemical and ultrastructural studies on subacute sclerosing panencephalitis
      and demyelination.

PMID- 4374516
TI  - Neutralizing antibodies to poliovirus and mumps virus in amyotrophic lateral
      sclerosis.

PMID- 4374517
TI  - Leiomyosarcoma of the breast originating from myothelium (myoepithelium).

PMID- 4374518
TI  - Greater frequency of viral respiratory infections in asthmatic children as
      compared with their nonasthmatic siblings.
AB  - A longitudinal clincal and microbiologic surveillance was conducted from October
      to May, 1971-72, on 16 children with infectious asthma and 15 of their
      nonasthmatic siblings. Asthmatic children experienced a significantly greater
      frequency of viral respiratory infections than did nonasthmatic ones (5.1 vs. 3.8
      per subject). This increased incidence appeared to be largely the result of a
      greater number of rhinovirus infections. While respiratory infections of
      identical etiology that occurred concurrently in an asthmatic and his sibling
      were equivalent in severity, illnesses were longer (but not significantly so) in
      asthmatic children.

PMID- 4374519
TI  - Cerebrospinal fluid: presence of virus unaccompanied by pleocytosis.

PMID- 4374520
TI  - Pertussis: persistent problems.

PMID- 4374521
TI  - Proceedings: Increase in the cyclic AMP content of rat striatum produced by a
      cyclic analogue of dopamine.

PMID- 4374523
TI  - Proceedings: Halothane and the depression of synaptic transmission through the
      perforant path synapses of the dentate gyrus of the hippocampal formation.

PMID- 4374522
TI  - Calcium release in relation to permeability changes in toad bladder epithelium
      following antidiuretic hormone.
AB  - 1. Methods for measuring the release of (45)Ca from isolated urinary bladders of
      toads (Bufo marinus) pre-loaded with this isotope have been devised. One method
      allowed separate collection from the mucosal and serosal surfaces of the
      bladders.2. Reducing the ambient calcium concentration reduced the rate of (45)Ca
      efflux suggesting that efflux of radiolabel represents calcium exchange.3.
      Antidiuretic hormone, theophylline and prostaglandin E(1) all increased calcium
      efflux, while lanthanum and amphotericin were without effect. Cyclic AMP caused
      only an inhibition of calcium release.4. The increase in (45)Ca efflux due to
      antidiuretic hormone came exclusively from the mucosal side. Experiments with
      EGTA suggest that the calcium entering the mucosal solution arises mainly from
      superficial sites in the mucosal membrane.5. The release of (45)Ca by hormone was
      not influenced by removal of sodium from the bathing solution. Low pH and
      amiloride reduced or abolished calcium release to hormone.6. The time course of
      calcium release from the mucosal surface due to hormone was rapid (commencing
      between 0.5 and 1.5 min after hormone application). Thus calcium release precedes
      the increase in sodium transport and hydro-osmotic flow following hormone, and
      appears to be at least as rapid as cyclic AMP generation in the tissue.7. The
      relationship between calcium release or exchange and the permeability changes in
      the bladder to water and to sodium, following hormone, are discussed.

PMID- 4374524
TI  - The Cinderella syndrome--young women in crisis.

PMID- 4374525
TI  - The pediatric nurse practitioner and preventive community mental health.

PMID- 4374526
TI  - East meets west: a transcultural aspect of the nurse-patient relationship.

PMID- 4374527
TI  - Transactional analysis strategies for dealing with pain.

PMID- 4374528
TI  - Issues between professional and paraprofessional nursing staff in community
      mental health.

PMID- 4374529
TI  - Psychiatric drugs and trends.

PMID- 4374530
TI  - Preventive intervention: healing in West Africa.

PMID- 4374531
TI  - Family nurse therapist: a model of communication.

PMID- 4374532
TI  - Rehabilitating heroin addicts.

PMID- 4374533
TI  - Los Angeles teen challenge: a resocialization program for drug abusers.

PMID- 4374534
TI  - Methadone maintenance.

PMID- 4374535
TI  - Patterning for a constructive relationship in problem isolation.

PMID- 4374536
TI  - Caring for patients with alcohol problems.

PMID- 4374537
TI  - International Trends: nursing in a changing world.

PMID- 4374538
TI  - Geriatrics: historical background & social security analysis.

PMID- 4374539
TI  - The clinical specialist as a change agent.

PMID- 4374540
TI  - The orgins of stromal reaction in breast carcinoma.

PMID- 4374541
TI  - Arteriovenous aneurysm due to glomangioma.

PMID- 4374542
TI  - Modification of the lymphocyte response to mitogens by cyclic AMP and GMP.

PMID- 4374543
TI  - Attempts to detect cytomegalovirus and rubella virus in infants with indirect
      inguinal hernias.

PMID- 4374545
TI  - An energy filter for biological electron microscopy.

PMID- 4374546
TI  - Direct determination of DNA nucleotide sequences: structure of a fragment of
      bacteriophage phiX172 DNA.

PMID- 4374544
TI  - Cell communication: a cyclic AMP mediated phenomenon.

PMID- 4374547
TI  - Letter to the editor: Fusion of Sendai viruses with model membranes.

PMID- 4374548
TI  - Hemophilus aegyptius restriction edonuclease cleavage map of the simian virus 40
      genome and its colinear relation with the hemophilus influenzae cleavage map of
      SV40.

PMID- 4374549
TI  - The methylated nucleotide sequences in HELA cell ribosomal RNA and its
      precursors.

PMID- 4374550
TI  - A comparison of the denatured states of alpha-lactalbumin and lysozyme.

PMID- 4374551
TI  - Structure of two adenovirus-simian virus 40 hybrids which contain the entire SV40
      genome.

PMID- 4374552
TI  - Deletion mutants of simian virus 40 generated by enzymatic excision of DNA
      segments from the viral genome.

PMID- 4374554
TI  - Relaxation spectra of the iron spin transition in methemoglobin.

PMID- 4374553
TI  - Structural and functional similarities within the coenzyme binding domains of
      dehydrogenases.

PMID- 4374555
TI  - Selective experimental chelation of calcium in the sinus node.

PMID- 4374556
TI  - Serological evidence of arbovirus infection in febrile hospitalized patients in
      Jakarta, Indonesia during 1970-71.

PMID- 4374557
TI  - [Multicystic dysplasia of the kidney in children. Apropos of 45 cases].

PMID- 4374559
TI  - [Tubulointerstitial nephropathies due to antibiotics].

PMID- 4374558
TI  - [Nephroepithelioma of a single kidney associated with neural manifestations and
      with IgM paraprotein].

PMID- 4374560
TI  - [Choice of an angiographic method in investigation of renal carcinoma (author's
      transl)].

PMID- 4374562
TI  - [Enzymes of microorganisms-with special reference to adenylate cyclase].

PMID- 4374561
TI  - [Differential diagnosis between renal adenocarcinoma and angiomyolipoma (author's
      transl)].

PMID- 4374563
TI  - [Vertebral angiography of posterior fossa tumors].

PMID- 4374564
TI  - [Flat type of early stomach carcinoma].

PMID- 4374565
TI  - Factors influencing the establishment of persistent infection of HVJ (Sendai
      virus)in L cells.

PMID- 4374566
TI  - Studies on complement-fixation reaction in equine infectious anemia. I.
      Development and activities of complement-fixing and complement fixation
      inhibiting antibodies.

PMID- 4374567
TI  - Studies on the neutralization of herpes simplex virus. VII. Reevaluation of the
      equilibrium theory concerning the unneutralizable persistent fraction.

PMID- 4374568
TI  - [Evaluation of the plasma ACTH assay method using the Radioimmunoassay Kit].

PMID- 4374569
TI  - [Case conference: after care of a patient following an extended hospitalization
      in a psychiatric hospital].

PMID- 4374570
TI  - Studies on the mechanism and prevention of local recurrence of carcinoma at the
      suture line after colonic resection.

PMID- 4374572
TI  - [Histoenzymological characteristics of the coronary arteries in
      arteriosclerosis].

PMID- 4374571
TI  - A pathologic-anatomical feature of carcinoma of large bowel in Japan.

PMID- 4374573
TI  - [Effect of quinidine, ajmaline and anapriline on certain metabolic processes in
      the heart conduction system].

PMID- 4374575
TI  - [Treatment of Dupuytren's contracture (literature review)].

PMID- 4374574
TI  - [Steroid receptor proteins of the heart. 1. Status of glucocorticoid (type 3)
      receptor proteins of the heart in stress and adrenalectomy].

PMID- 4374576
TI  - [Influence of hormones on the nervous system in infancy and childhood (author's
      transl)].

PMID- 4374577
TI  - [IgA-latex-test (author's transl)].

PMID- 4374578
TI  - [Acute hyperparathyroidism in primary water-clear cell hyperplasia: clinical and
      morphological findings (author's transl)].

PMID- 4374579
TI  - [In vitro corticosteroid biosynthesis in human adrenals. II. Comparison between
      normal and hyperplastic (Cushing) adrenals (author's transl)].

PMID- 4374581
TI  - [Prevention and early diagnosis of mental disorders].

PMID- 4374580
TI  - [Changes in the kinin system of the blood and the complement level in chronic
      pneumonia].

PMID- 4374583
TI  - [Possibilities of psychiatric intensive therapy].

PMID- 4374582
TI  - [The 5 stages in the recovery from neuroses].

PMID- 4374584
TI  - [Meaning and effect of dreams in psychotherapy].

PMID- 4374585
TI  - [3 nursing studies about activities in a psychiatric hospital. I. My activities
      in an acute department].

PMID- 4374586
TI  - [3 nursing studies about activities in a psychiatric hospital. II. My activities
      in the field of sociotherapy].

PMID- 4374587
TI  - [Open door treatment of mental patients].

PMID- 4374588
TI  - [3 nursing studies about activities in a psychiatric hospital. III. My activities
      in rehabilitation].

PMID- 4374589
TI  - [Is clinical experience in psychiatric nursing but a theater performance?].

PMID- 4374590
TI  - Cryptosporidiosis in the intestines of rhesus monkeys (Macaca mulatta).

PMID- 4374591
TI  - Effectiveness of footwear decontamination methods for preventing the spread of
      infectious agents.

PMID- 4374592
TI  - Fetal and postnatal growth retardation associated with gestational mumps virus
      infection of the rhesus monkey.

PMID- 4374593
TI  - Iron balance in the mouse.

PMID- 4374594
TI  - An evaluation of requirements for pathological incineration facilities.

PMID- 4374595
TI  - Population frequency of erythrocyte antigens in the rhesus monkey.

PMID- 4374597
TI  - Evaluating feeding cycles of small rodents.

PMID- 4374596
TI  - Cysticercosis in rabbits: incidence and lesions of the naturally occurring
      disease in young domestic rabbits.

PMID- 4374598
TI  - Pasteurella multocida infection in the opossum (Didelphis virginiana).

PMID- 4374599
TI  - An isolator for the collection of feces from chickens infected with coccidia.

PMID- 4374600
TI  - The time and pattern of eruption of the permanent teeth of the cat.

PMID- 4374601
TI  - An improved method for fibrin clot recovery.

PMID- 4374602
TI  - Mechanical milk collection from mice for Bittner virus isolation.

PMID- 4374603
TI  - Naturally occurring Sendai virus disease of mice.

PMID- 4374604
TI  - An ultrahigh-efficiency filter for use with flexible film germfree animal
      isolators.

PMID- 4374605
TI  - Exteriorized ureters in the dog.

PMID- 4374606
TI  - A simple method for repeated plasmapheresis of the horse.

PMID- 4374607
TI  - Effects of off-frequency detection in brief-tone audiometry.

PMID- 4374608
TI  - Detection and differentiation of primary hyperlipoproteinemias.

PMID- 4374609
TI  - Fine structural changes in the lateral vestibular nucleus of aging rats.

PMID- 4374610
TI  - Hepatic artery-portal vein fistula with hepatic cirrhosis, hepatoma and bleeding
      esophageal varices.

PMID- 4374611
TI  - Primary linitis plastica carcinoma of the colon.

PMID- 4374612
TI  - Selective metabolic pathways for noradrena-line in the peripheral and in the
      central nervous system.

PMID- 4374613
TI  - Learning, brain noradrenaline and the pituitary--adrenal axis.

PMID- 4374614
TI  - Effect of 6-hydroxydopamine on agonistic behaviour elicited by stimulation of the
      hypothalamus in the cat.

PMID- 4374615
TI  - [Recruitment in the calibrated Weber-test after stapedectomy (author's transl)].

PMID- 4374616
TI  - Sensitized guinea-pig lung: altered adenylate cyclase stimulation by epinephrine.

PMID- 4374621
TI  - Lipids of cultured hepatoma cells: IV. Effect of serum and lipid upon cellular
      and media neutral lipids.

PMID- 4374622
TI  - Lipids of cultured hepatoma cells: V. Distribution of isomeric monoene fatty
      acids in individual lipid classes.

PMID- 4374623
TI  - Skin cancer.

PMID- 4374624
TI  - [Virus-induced hematologic diseases].

PMID- 4374625
TI  - [Sparteine sulfate (Depasan) in pre- and after treatment of
      electrocardioversion].

PMID- 4374626
TI  - Mammalian membrane marker enzymes: sensitive assay for 5'-nucleotidase and assay
      for mammalian 2',3'-cyclic-nucleotide-3'-phosphohydrolase.

PMID- 4374627
TI  - Spin-label measurements in membranes. With appendix: a use of computers in EPR
      spectroscopy.

PMID- 4374628
TI  - Isolation and characterization of glycosphingolipid from animal cells and their
      membranes.

PMID- 4374629
TI  - C55-isoprenoid alcohol phosphokinase: an enzyme soluble in organic solvents.

PMID- 4374631
TI  - Coulter electronic particle counter assay.

PMID- 4374630
TI  - Cell hybridization.

PMID- 4374632
TI  - Assays for agglutination with lectins,.

PMID- 4374633
TI  - An assay for labeled lectin binding to cell surfaces.

PMID- 4374634
TI  - High-yield preparation of morphologically intact isolated parenchymal cells from
      rat liver.

PMID- 4374635
TI  - Isolation of adult rat liver macrophages (Kupffer cells).

PMID- 4374636
TI  - Isolation of renal tubules.

PMID- 4374637
TI  - Isolation of intestinal mucosa cells.

PMID- 4374639
TI  - The isolation and culture of thyroid cells.

PMID- 4374638
TI  - Isolation of adrenal cortex cells--hormone responses.

PMID- 4374640
TI  - Yeast lipid mutants: isolation, maintenance, and spin label studies.

PMID- 4374642
TI  - [Initial pathways of pyruvate metabolism in phototrophic bacteria].

PMID- 4374641
TI  - [Reduction of phosphoglyceric acid in extracts of Hydrogenomonas eutropha Z-1].

PMID- 4374643
TI  - [The effect of the agents of anaerobic gas infection on human granulocytes].

PMID- 4374644
TI  - [Latest observations on the pathogenesis of non-obstructive chronic urinary tract
      infections].

PMID- 4374645
TI  - [Oral contraceptives and arterial hypertension].

PMID- 4374646
TI  - Measles, canine distemper and respiratory syncytial virions and nucleocapsids. A
      comparative study of their structure, polypeptide and nucleic acid composition.

PMID- 4374648
TI  - Pathogenetic aspects of measles virus infections.

PMID- 4374647
TI  - Ribonucleic acid synthesis in rinderpest virus infected cells.

PMID- 4374649
TI  - Parainfluenza 1 virus and multiple sclerosis: the conversion of 6/94 virus
      released from human brain cells and other mammalian cells into and infectious
      form by passage in macrophages.

PMID- 4374650
TI  - [Ectopic localization of mixed tumors of the salivary glands].

PMID- 4374651
TI  - [Conjugated estrogens as a hemostatic in urology with special reference to their
      intramuscular administration].

PMID- 4374652
TI  - Isolation, genetics and survival characteristics of thermo-sensitive mutants of
      yeast.

PMID- 4374653
TI  - [The prediction of adult height in children (author's transl)].

PMID- 4374654
TI  - [Treatment of uremic osteopathy. Effects of vitamin D metabolites and vitamin D
      analogs in chronic uremia and experimental renal insufficiency].

PMID- 4374655
TI  - [Anticonvulsants and vitamin D metabolism (author's transl)].

PMID- 4374656
TI  - [Current conceptions on the biochemical mode of action of vitamin D (author's
      transl)].

PMID- 4374657
TI  - [Combined cytostatic treatment of malignant brain tumors (author's transl)].

PMID- 4374658
TI  - [Myocardial infarction and satisfactory place of work, an important after-care
      problem (author's transl)].

PMID- 4374659
TI  - [The value of plate thermography in the diagnosis of the breast (author's
      transl)].

PMID- 4374660
TI  - [Letter: "Huneke's neurol therapy"].

PMID- 4374661
TI  - Electrophoretic protein and enzyme patterns and antigenic structure in
      Verticillium dahliae and V. albo-atrum.

PMID- 4374662
TI  - Isolation of bovine rhinovirus from calves with respiratory disease.

PMID- 4374663
TI  - Isolation of bacteria and viruses from aborted bovine fetuses.

PMID- 4374664
TI  - [Problems of the action of cyclic AMP on malignant brain tumors (author's
      transl)].

PMID- 4374666
TI  - [Cerebellar tumors manifesting fibrosis and hemangiomatous pattern (author's
      transl)].

PMID- 4374665
TI  - [Intramedullary spinal cord tumors--surgical technique (author's transl)].

PMID- 4374667
TI  - Ocular flutter and downbeat nystagmus: a case with supratentorial origin?

PMID- 4374668
TI  - Neural neoplasms in Thailand: a study of 2,897 cases.

PMID- 4374669
TI  - Gastrointestinal involvement in von Recklinghausen's neurofibromatosis.

PMID- 4374671
TI  - [Millipore filters 30 samples at one time].

PMID- 4374670
TI  - [Development of histological lesions in ulcerative rectocolitis after medical
      treatment].

PMID- 4374673
TI  - The epidemiology of Type 2 (genital) herpes simplex virus infection.

PMID- 4374672
TI  - Infectious bovine rhinotracheitis virus and its role in bovine abortion.

PMID- 4374675
TI  - The dentinal changes in regional odontodysplasia.

PMID- 4374674
TI  - Osteochondromatosis of the temporomandibular joint. Report of a case.

PMID- 4374676
TI  - Effects of phenylbutazone on the activities of cathepsin D, collagenolytic
      cathepsin and collagen peptidase in turpentine-induced granuloma.

PMID- 4374677
TI  - [Host cell reactions on virus infection (author's transl)].

PMID- 4374678
TI  - [Structure and dynamics of membranes. Application of nuclear magnetic resonance
      and electron spin resonance (author's transl)].

PMID- 4374679
TI  - [Functions of the hypothalamo-hypophyseal-adrenal systems in the early period of
      shock caused by crushing of soft tissues].

PMID- 4374680
TI  - Studies on the pathogenetic mechanism of I-cell disease in cultured fibroblasts.

PMID- 4374681
TI  - The long term effects of infection in early life (long view II). Presidential
      Address delivered at the Symposium on the Long Term Effects of Events in Early
      Life, American Pediatric Society annual meeting, May 1, 1974, Washington, D.C.

PMID- 4374682
TI  - [Letter: Silymarine against acute degenerative hepatitis in mice induced by FV 3.
      Experimental study of its activity].

PMID- 4374683
TI  - [The method of "teasing" in morphological study of the peripheral nerve. Value in
      human pathology. 1-Wallerian degeneration].

PMID- 4374684
TI  - [Hepatoma-Australia antigen association. A case studied by electron microscopy
      and immunofluorescence].

PMID- 4374685
TI  - [Gas gangrene. Etiologic clinical and current therapeutic aspects].

PMID- 4374686
TI  - [Acquired platelet disorder. The essential element in the pathogenesis of
      hemorrhage in certain malignant hemopathies].

PMID- 4374687
TI  - [Kinetic study of chrome-51 labelled platelets in hereditary thrombocytopenia].

PMID- 4374688
TI  - Nursing care study: fructose-1, 6-diphosphatase deficiency-1.

PMID- 4374689
TI  - Fructose-1, 6 diphosphatase deficiency. 2.

PMID- 4374690
TI  - [Case of dysostosis multiplex with features of mucolipidosis II (I-cell
      disease)].

PMID- 4374691
TI  - [Variation in blood lipid contents during the acute phase of heart infarct].

PMID- 4374692
TI  - Influence of ouabain on active sodium transport, stimulated by cyclic nucleotides
      across the frog skin in vivo.

PMID- 4374694
TI  - Bronchial asthma.

PMID- 4374696
TI  - Rapid method for the isolation of plasma membranes from a murine fibrosarcoma
      using an aqueous two-phase polymer system.

PMID- 4374695
TI  - [Amebiasis].

PMID- 4374697
TI  - [Insulin receptors and mechanism of the action of insulin in the body].

PMID- 4374698
TI  - [Gumactid-28 (clinical use)]?14Gumaktid-28 (klinicheskoe ispolzavanie)

PMID- 4374700
TI  - Dual infection with endogenous herpes- and C-type viruses in cultured cells
      derived from normal and leukemic guinea pigs.

PMID- 4374699
TI  - [Effect of ACTH and hydrocortisone during the action of high external temperature
      on the body].

PMID- 4374701
TI  - Cyclic AMP and thyroid hormone: inhibition of epiphyseal cartilage cyclic 3',5'
      nucleotide phosphodiesterase activity by L-triiodothyronine.

PMID- 4374702
TI  - Tumor facilitation in a syngeneic host-tumor system.

PMID- 4374703
TI  - Production of herpes simplex antisera with increased type specificity in guinea
      pigs by antibody suppression.

PMID- 4374704
TI  - Effects of glucagon upon rat liver mitochondria in vivo.

PMID- 4374705
TI  - Hormonal stimulation of substrate utilization in brown adipose tissue of cold
      acclimated rats.

PMID- 4374706
TI  - Angiotensin antagonist and possible release of catecholamine.

PMID- 4374707
TI  - Irreversible inhibition of angiotensin II activity on the rat uterus by an
      alkylating angiotensin derivative.

PMID- 4374708
TI  - The origin of an E.S.R signal at g equals 2.03 from normal rabbit liver and the
      effects of nitrites upon it.

PMID- 4374693
TI  - Infectious diseases: annual review of significant publications.

PMID- 4374709
TI  - A comparison of thermal neutron and gamma ray sensitivities of common TLD
      materials.

PMID- 4374710
TI  - Induction of free radicals in DNA by proflavine and visible light: influence of
      oxygen and ionic strength.

PMID- 4374711
TI  - Influence of ACTH and adrenal hormones on the amplitude and habituation of the
      flexor reflex.

PMID- 4374712
TI  - REM sleep deprivation impairs bar-press acquisition in rats.

PMID- 4374713
TI  - Determination of renin activity of kidney homogenates.

PMID- 4374714
TI  - The cytochrome and phospholipid content of the mitochondrial membrane of the
      neonatal and adult rat kidney.

PMID- 4374715
TI  - The metabolic activity and equipment of the mitochondrial membranes of different
      tissues.

PMID- 4374716
TI  - [Comparison of the content of the laboratory and home dreams.-- A
      psychophysiological study on dreams of normal and schizophrenic subjects
      (author's transl)].

PMID- 4374717
TI  - [A study on the relationship between hippocampal theta rhythm and rapid eye
      movements (author's transl)].

PMID- 4374719
TI  - [On radiogenic peripheral neuropathies following telecobalt irradiation in the
      abdominal cavity (author's transl)].

PMID- 4374718
TI  - Endocrine alterations in delirium tremens.

PMID- 4374720
TI  - The influence of pituitary peptides on brain centers controlling autonomic
      responses.

PMID- 4374721
TI  - The ontogenetic development of hypothalamo-hypophyseal relations.

PMID- 4374722
TI  - The adrenal glands, estrogen, and the control of parturition in the guinea pig.

PMID- 4374723
TI  - The parafasicular area as the site of action of ACTH analogs on avoidance
      behavior.

PMID- 4374724
TI  - Psychobiological aspects of lactation in rats.

PMID- 4374725
TI  - Effects of adrenalectomy and treatments with ACTH and glucocorticoids on
      isolation-induced aggressive behavior in male albino mice.

PMID- 4374726
TI  - [Tetanus, typhoid and smallpox antibodies in the sera of men 22-46 years of age].

PMID- 4374727
TI  - [Length of time poliovirus is infectious following contamination of fabrics].

PMID- 4374728
TI  - [Lipoprotein measurement by immunocrit method (II) (author's transl)].

PMID- 4374729
TI  - [Neuromuscular blocking, its agents and antagonists].

PMID- 4374730
TI  - Nicotine and its metabolities. IV. Formation of the nicotine analogue of DPN by
      pig brain DPNase.

PMID- 4374731
TI  - Effect of epinephrine and adenosine cyclic 3',5' - monophosphate on heart
      mitochondrial and microsomal calcium uptake.

PMID- 4374732
TI  - Adrenergic subsensitivity of the rat brain during chronic ethanol ingestion.

PMID- 4374733
TI  - The increase of cyclic AMP in rat's brain during anoxia.

PMID- 4374734
TI  - Experimental infection of sheep with a type 3 reovirus of ovine origin.

PMID- 4374736
TI  - [Granular-cell tumors of the neurohypophysis. Apropos of a case].

PMID- 4374735
TI  - [The use of alpha-1-24 ACTH for rapid adrenal stimulation (author's transl)].

PMID- 4374738
TI  - [Amebiasis in a seaman of Polish merchant marine (author's transl)].

PMID- 4374737
TI  - [Atypical ophthalmological signs in hypophyseal adenomas].

PMID- 4374739
TI  - [Experimental study of the cytopathogenic effects of Herpes simplex virus].

PMID- 4374741
TI  - Adenocarcinoma of the lung 101 cases including 32 cases of bronchiolar cell
      carcinoma. A histopathological study.

PMID- 4374740
TI  - [7 cases of ameloblastoma recurrence].

PMID- 4374742
TI  - Short-term psychiatric care from a theoretical planning and empirical point of
      view.

PMID- 4374743
TI  - [Chronic focal glomerulonephritis and chronic persistent hepatitis following
      kidney transplantation. Detection of Hepatitis B and Epstein-Barr virus antigen].

PMID- 4374744
TI  - [Clinical demonstrations].

PMID- 4374746
TI  - [Reports from the liver unit of the international university hospital in paris
      and the research unit. introduction].

PMID- 4374745
TI  - Cellular mode of action of diuretics.

PMID- 4374747
TI  - [Methodology of epidemiological studies in drug hepatotoxicity].

PMID- 4374748
TI  - [Use of a isoniozid-rifompicin drug hepatotoxicity screening technic in
      tuberculosis therapy].

PMID- 4374749
TI  - [Spleen study in laparoscopy].

PMID- 4374750
TI  - [Late aseptic gallbladder necroses in patients with multiple injuries].

PMID- 4374751
TI  - [Solitary rectal ulcer].

PMID- 4374752
TI  - [Closed injuries of the thorax, Therapeutic problems].

PMID- 4374754
TI  - [Primary malignant lymphomas of the stomach. Review of the literature].

PMID- 4374753
TI  - [Study of certain constituents of amniotic fluid during the final trimester of
      pregnancy. (apropos of 105 cases)].

PMID- 4374755
TI  - [Etiological diagnosis of gastrointestinal hemorrhage in a patient with liver
      cirrhosis].

PMID- 4374756
TI  - [Surgical treatment of acute cholecystitis].

PMID- 4374757
TI  - [Heart failure of undetermined origin].

PMID- 4374758
TI  - [Hyperkalemias in cardiac patients].

PMID- 4374760
TI  - [Nonsecreting myeloma revealed by medullary compression].

PMID- 4374759
TI  - [Mitral insufficiency with mesotelesystolic murmur].

PMID- 4374761
TI  - [Hoarseness].

PMID- 4374762
TI  - The impact of scientific models on clinical psychopharmacology: an internist's
      view.

PMID- 4374763
TI  - Origin of recessive lethal mutations suppressed by the Y chromosome in Drosophila
      melanogaster under the influence of radiation and ethyl methanesulfonate.

PMID- 4374764
TI  - Genetic bases of the UV resistance of Salmonella. Communication II. uvrB-mutants
      of Salmonella abony.

PMID- 4374765
TI  - Blood groups of the ABO system and the relationship to certain malignant tumors
      in children.

PMID- 4374767
TI  - Paraphysial cysts of the third ventricle.

PMID- 4374766
TI  - Seventeen cases of hepatectomy.

PMID- 4374768
TI  - Primary liver cancer rate and aflatoxin intake in a high cancer area.

PMID- 4374769
TI  - Effect of protein energy malnutrition on the renal function and extracellular
      fluid volume of the rat.

PMID- 4374770
TI  - Metabolic effect of conjugated oestrogens (USP) on glucose tolerance.

PMID- 4374771
TI  - [Dependence on hypnotics. Causes of the development and advice on how to avoid
      it].

PMID- 4374772
TI  - [Angiotensin blockade and hypertension].

PMID- 4374773
TI  - [Letter: Prevention against varicella and herpes zoster in individuals with
      impaired immunological defence].

PMID- 4374774
TI  - [A talk about: continuity of nursing care].

PMID- 4374775
TI  - Effects of dibutyryl cyclic AMP on contractile performance of isolated heart
      muscle depressed by thiamylal and halothane.

PMID- 4374776
TI  - Effects of dibutyryl cyclic AMP on the pulmonary hemodynamics.

PMID- 4374777
TI  - [Phosphatase activity in saliva and blood in parodontosis].

PMID- 4374779
TI  - The results of fast neutron therapy from the Medical Research Council's cyclotron
      at Hammersmith hospital, London, with particular reference to tumours of the head
      and neck.

PMID- 4374778
TI  - [Herpetic paronychia in a patient with primary herpetic gingivostomatitis].

PMID- 4374780
TI  - A study on the stability of an estrogen-protein conjugate in vivo and under in
      vitro conditions.

PMID- 4374781
TI  - Studies on the metabolism of steroid hormones. Part II. Reversible steroid
      protein interactions via enol intermediates.

PMID- 4374782
TI  - [Side effects and complications of antibiotic therapy].

PMID- 4374783
TI  - [Effect of kdiney transplantation on polyneuropathies developing during treatment
      by hemodialysis].

PMID- 4374784
TI  - [Cancer of the wall of a solitary cyst of the kidney].

PMID- 4374785
TI  - Human prostatic carcinoma in cell culture: preliminary report on the development
      and characterization of an epithelial cell line (EB 33).

PMID- 4374788
TI  - [Comparative study on the sensitivity of PK cell line, HeLa cells and primary
      piglet kidney cells to infection with infectious bovine rhinotracheitis
      infectious pustular vulvovaginits of virus of cattle (IBR - IPV)].

PMID- 4374789
TI  - The tonsils in the pathogenesis of disease.

PMID- 4374790
TI  - International control of equine infectious diseases.

PMID- 4374792
TI  - Infection of chicks with infectious bursal disease and its effect on the carrier
      state with Newcastle disease virus.

PMID- 4374791
TI  - Pox in racing pigeons.

PMID- 4374793
TI  - [Literature survey on the contrast-radiography study of the thoracic duct and the
      adjacent lymph nodes in man].

PMID- 4374794
TI  - [Obtaining and testing of a trivalent hyperimmune serum against parainfluenza-3,
      adenovirus I and infectious rhinotracheitis in calves].

PMID- 4374795
TI  - [The effect of vitestrol and hypophysin on antibody production in rabbits].

PMID- 4374797
TI  - [Mixed virus infections associated with respiratory diseases in calves].

PMID- 4374796
TI  - [Isolation of viruses from semen of cattle bulls and their effect on fertility of
      cows].

PMID- 4374798
TI  - Evidence for B-cell origin of reticulum cell sarcoma.

PMID- 4374799
TI  - Unusual glomerular change in cytomegalic inclusion disease.

PMID- 4374800
TI  - Cardiac muscle cell damage induced by restraint stress.

PMID- 4374801
TI  - [Hepatocellular glycogenosis and the genesis of so-called hyperplastic liver
      nodules in thioacetamide intoxicated rats (author's transl)].

PMID- 4374802
TI  - Skeletal maturity of children 6-11 years, United States.

PMID- 4374803
TI  - [Reproductive function in women after chemotherapy for trophoblastic tumors].

PMID- 4374804
TI  - [Role of gluconeogenesis in the maintenance of normoglycemia in the body of
      animals with transplanted tumors].

PMID- 4374805
TI  - [Activity of NAD-pyrophosphorylase in the cell nuclei of normal liver and
      transplanted hepatoma].

PMID- 4374806
TI  - [Immunological studies in carcinogenesis. Transplantation of embryonic thymus
      into oncological patients].

PMID- 4374807
TI  - [Adenovirus and herpesvirus infections of human embryo lung organ culture].

PMID- 4374808
TI  - [Electron microscopy in the rapid diagnosis of diseases caused by poxvirus and
      herpesvirus].

PMID- 4374810
TI  - [Concentration of rhinoviruses].

PMID- 4374809
TI  - [Immunopathology in viral infections].

PMID- 4374812
TI  - [Metacentric chromosomes in the karyotype of spleen lines of BALB/c mice,
      chronically infected with Friend and Rauscher leukemia viruses].

PMID- 4374813
TI  - [Functioning of Sendai virus ribonucleoprotein in cells of permissive systems].

PMID- 4374811
TI  - [Biological activity of the polyribonucleotide complex (poly-G)-(poly-C) in
      relation to the structural characteristics of the original polyribonucleotides].

PMID- 4374814
TI  - [Mechanism of viral variability. Spontaneous mutation process in Western equine
      encephalomyelitis virus in cells with active and defective repair systems].

PMID- 4374816
TI  - [Mechanism of viral variability. Methylmethanesulfonate-induced mutation process
      in Western equine encephalomyelitis virus in cells with active and defective
      repair systems].

PMID- 4374815
TI  - [Virological, cytological and karyological characteristics of clones, isolated
      from L cell cultures chronically infected with vesicular stomatitis virus].

PMID- 4374817
TI  - [Morphology of type C oncornaviruses in continuous monkey sarcoma AP-1 cell
      line].

PMID- 4374818
TI  - [Morphogenesis of a virus similar to foamy agent].

PMID- 4374819
TI  - [Optimal conditions for production of complement-fixing antigens of para
      influenza viruses].

PMID- 4374821
TI  - [Sarcoma induction in Dzungarian hamsters using Rous sarcoma virus (Carr-Zilber
      strain)].

PMID- 4374820
TI  - [Proteolytic enzymes in virological studies].

PMID- 4374822
TI  - [Isolation of oncornaviruses from patients with chronic myeloleukosis].

PMID- 4374824
TI  - [Isolation of parainfluenza virus type 4B in Kiev].

PMID- 4374823
TI  - [Phenomenon of tolerance (hyporeactivity) in interferonogenesis].

PMID- 4374825
TI  - [Examination for sera from Japanese quail (Coturnix coturnix japonica) for the
      presence of antibodies to avian viruses].

PMID- 4374826
TI  - [Possible vertical transmission of oncornaviruses in man].

PMID- 4374827
TI  - [Use of bentonite for concentration and purification of enteroviruses].

PMID- 4374828
TI  - [Preparation of immune serums to rhinoviruses].

PMID- 4374830
TI  - [Editorial: Oncornaviruses--contaminants of cell cultures].

PMID- 4374829
TI  - [Discovery of viruses and the 1st doctoral dissertation on virology].

PMID- 4374831
TI  - [Antiviral action of nucleases and histones].

PMID- 4374832
TI  - [Abortive infections produced by myxoviruses and rhabdoviruses and their possible
      causes].

PMID- 4374833
TI  - [Interaction of the causative agent of lymphogranuloma venereum with macrophages
      from immune animals in vitro].

PMID- 4374834
TI  - [Study of Sendai virus proteins].

PMID- 4374835
TI  - [Hematologic and enzymatic tests in agricultural workers with acute intrathion
      poisoning].

PMID- 4374836
TI  - Infectious mononucleosis at the United States Military Academy. A prospective
      study of a single class over four years.
AB  - A prospective study of EB virus infections was initiated in July, 1969 in the
      entering class of 1401 cadets, at the U.S. Military Academy at West Point, N.Y.
      and continued over 4 yr. On entry 63.5% possessed EBV antibody and 36.5 lacked
      EBV antibody. The rate of antibody prevalence varied with the geographic area
      from which the cadet originated.Except in two cadets already ill on first
      bleeding no evidence of clinical infectious mononucleosis (I.M.) occurred over
      the 4 yr period in the 890 cadets entering the Academy with EBV antibody. Among
      437 cadets without antibody on entry, 54 or 12.4% were infected (seroconverted)
      in the freshman year; 15 of these had clinical I.M., 12 had suggestive I.M., and
      39 had no known mono-like illness. The annual infection rates in susceptible
      cadets in the second, third, and fourth years were 24.4, 15.1, and 30.8 per 100,
      respectively. Of 201 cadets infected with EBV over 4 yr only 26.4% were
      manifested by heterophile positive clinical infectious mononucleosis. Overall,
      46% of the 437 cadets entering without EBV antibody became infected over 40 mo of
      serologic observation; definite clinical infectious mononucleosis developed in 53
      cadets, a clinical attack rate of 12.1 per 100 for 4 yr. The EBV infection rate
      among exposed and susceptible roommates of known cases was no higher than in
      roommates not so exposed.Elevations of EBV-specific and total IgM occurred during
      acute illness and disappeared in late convalescence. Total IgG and IgA levels
      were less commonly elevated. EBV-specific-IgM antibody was demonstrable during
      the acute illness but was absent 12 mo later. Analysis of EBV infection rates
      revealed no difference among persons of different ABO blood groups.

PMID- 4374837
TI  - [Determination of skeletal maturation in childhood (author's transl)].

PMID- 4374838
TI  - [Method for the determination of isoenzymes of alkaline phosphatase].

PMID- 4374839
TI  - [Proceedings: The effect of diphosphonate on crystal formation of calcium
      phosphates in vitro].

PMID- 4374840
TI  - [Phospholipids and oxidative phosphorylation].

PMID- 4374841
TI  - [Structure and function of matrix RNAs in living cells].

PMID- 4374842
TI  - [Primary mechanism of cellular injury in ischemic tissues].

PMID- 4374843
TI  - [Changes in the degree of resistance to homologous virus in clones obtained from
      chronically infected cultures].

PMID- 4374844
TI  - [Case of oculo-dento-digital dysplasia].

PMID- 4374845
TI  - [Fibroma of the nasopharynx in an adult].

PMID- 4374847
TI  - [X-ray and angiographic comparisons in juvenile fibroma of the base of the
      skull].

PMID- 4374846
TI  - [Kinin system of the blood plasma and leukocytes and the prospects for studying
      it in otolaryngology].

PMID- 4374848
TI  - [Action of cold in glomic tumors of the middle ear and base of the skull].

PMID- 4374849
TI  - [Ultrastructural studies of periapical nerve elements].

PMID- 4374850
TI  - Microscopic findings in the lungs of calves aerosolized with Pasteurella
      hemolytica and treated to alter pulmonary clearance.

PMID- 4374851
TI  - The effect of azetidine-2-carboxylic acid on the biosynthesis of collagen in rat
      granuloma.

PMID- 4374852
TI  - Biochemical studies on some new analogues of adenosine-3'5'-cyclic phosphate,
      including isoguanosine-3 ,5-cylic phosphate.

PMID- 4374853
TI  - The estrogen test: an aid in differential cytodiagnosis.

PMID- 4374854
TI  - Trauma: hormonal factors with special reference to diabetes mellitus.

PMID- 4374855
TI  - Normal carbohydrate metabolism and carbohydrate metabolism in trauma.

PMID- 4374857
TI  - General metabolic response to trauma including pain influence.

PMID- 4374856
TI  - Metabolism of alcohol.

PMID- 4374858
TI  - Effects of triparanol and 20,25-diazacholesterol in CNS of rat: morphological and
      biochemical studies.

PMID- 4374859
TI  - The fine structural localisation of thiamine pyrophosphatase and adenosine
      triphosphatase in neural tumours induced by N-ethyl-N-nitrosourea in rats.

PMID- 4374860
TI  - Fatal polymyositis: morphogenesis and ultrastructural features.

PMID- 4374861
TI  - Hypertrophic neuropathy in a dog.

PMID- 4374862
TI  - Glioblastoma multiforme of the medulla oblangata.

PMID- 4374863
TI  - Histochemically demonstrable non-specific cholinesterase as an indicator of
      peripheral nerve lesion in carbon disulphide-induced polyneuropathy.

PMID- 4374864
TI  - [Morphological studies on the oncotype of the medulloblastoma (author's transl)].

PMID- 4374865
TI  - Spino-olivo-ponto-cerebello-nigral atrophy with Lewy bodies and binucleated nerve
      cells: a case report.

PMID- 4374866
TI  - Physical development and performance capacity in a group of diabetic children and
      adolescents.

PMID- 4374867
TI  - Relationship between biological age, habitual physical activity and
      morphological, physiological characteristics of 12 and 13 year old boys.

PMID- 4374868
TI  - Skeletal maturation and physical fitness of 12 to 15 year old boys.

PMID- 4374869
TI  - Anthropometrical data, muscle-strength, physiological and selected motor ability
      factors of 11 year old boys.

PMID- 4374870
TI  - Geographical pathology of gastric carcinoma.

PMID- 4374871
TI  - The permeability pathways in the walls of intesinal submucosal arterioles in
      acute angiotensin-induced hypertension in rats.

PMID- 4374872
TI  - Ultrastructural pathological changes in intestinal submucosal arterioles in
      angiotensin-induced acute hypertension in rats.

PMID- 4374873
TI  - Multicentric and bilateral appearance of lobular carcinoma in situ of the breast.

PMID- 4374874
TI  - Concentrations of renin and renin substrate in plasma of rabbits during pregnancy
      and the post partum period.

PMID- 4374875
TI  - Renin inactivation in vitro in pregnant and post partum rabbit uterine and kidney
      tissue.

PMID- 4374876
TI  - The ability of various insulins and insulin fragments to inhibit the angiotensin
      I converting enzyme.

PMID- 4374877
TI  - Effects of ACTH and HCG on ovarian oestrogen and progesterone secretion in dogs
      pretreated with HCG.

PMID- 4374878
TI  - [Thin layer chromatography of polymyxin E and its methanesulfonate].

PMID- 4374879
TI  - [Effect of gamma irradiation on aqueous solutions of viomycin sulfates].

PMID- 4374880
TI  - Human herpes simplex virus infections.

PMID- 4374881
TI  - Viral infections of the developing nervous system.

PMID- 4374882
TI  - Slow infections of the nervous system and the subacute spongiform
      encephalopathies.

PMID- 4374883
TI  - Progressive multifocal leukoencephalopathy.

PMID- 4374884
TI  - Advances in diagnosis and treatment of solid tumors in children.

PMID- 4374886
TI  - Effects of "Bordetella pertussis" on hemic colony-forming cells and immune
      response.

PMID- 4374887
TI  - The Tecumseh study of respiratory illness. VII. Further observations on the
      occurrence of respiratory syncytial virus and Mycoplasma pneumoniae infections.
AB  - The occurrence of infection with respiratory syncytial (RS) virus and Mycoplasma
      pneumoniae was determined over a 6-year period among residents of Tecumseh,
      Michigan by isolation and serology. RS virus infection was detected for a
      variable time each year during the months extending from November to May. There
      was little viral activity in intervals between these periods of prevalence, which
      occurred on an alternating short-long cycle. Higher infection rates were detected
      in periods preceding the long interval than were detected in periods preceding
      the short interval. Viruses isolated from serial annual outbreaks did not show
      any sequential changes in antigens, although some variation in antigenic
      structure was apparent. Infections were common in school-age children, indicating
      the role of this population in transmission. Young girls were infected as often
      as young boys, suggesting that observed differences in occurrence of illness must
      be related to differences in expression of infection. In contrast to RS virus, M.
      pneumoniae did not appear and disappear annually, but like it, the school-age
      group was most heavily involved in infection.

PMID- 4374885
TI  - Regulation of lysosomal enzyme secretion: role in inflammation.

PMID- 4374888
TI  - The malignant cell and its membranes.
AB  - In this brief review the hypothesis that altered membrane proteins and
      glycoproteins may be critical mediators of malignant expression is discussed.
      Examples of alterations of membrane proteins in malignancy are presented. Data is
      summarized showing changes in the carbohydrate components of glycoproteins of
      surface and internal membranes of malignant cells in culture as compared to their
      normal counterparts.

PMID- 4374891
TI  - [Effect of glucocorticoids on the fibrin-stabilizing factor in dysfunctional
      uterine hemorrhages].

PMID- 4374892
TI  - [Certain indicators of the functional state of the placental mitochondria at
      different periods of pregnancy].

PMID- 4374890
TI  - Effects of the lonophore A23187 on blood platelets I. Influence on aggregation
      and secretion.
AB  - A23187 is an antibiotic ionophore which transports divalent cations across cell
      membranes into the cytoplasm and releases cations from intracellular storage
      sites. The present investigation has studied the influence of A23187 on blood
      platelet aggregation and secretion. A23187 added to stirred C-PRP produced
      concentration-dependent aggregation and release of (14)C-serotonin. Calcium ions
      potentiated the response of platelets in washed suspensions to A23187, but they
      were not required for ionophore-induced aggregation or release. N-ethylmaleimide
      and agents which increase the level of cyclic 3',5'-adenosine monophosphate
      (cAMP) in platelets were effective inhibitors of A23187-induced aggregation and
      secretion.Platelets incubated with (45)Ca(++) before addition of A23187 increased
      their content of isotope by 50% within 45 seconds after exposure to the
      ionophore. The results indicate that an increase in the cytoplasmic concentration
      of calcium ions from intracellular sources may be the critical event in
      triggering platelet contraction and the release reaction. Increased
      concentrations of cAMP may inhibit the platelet response to A23187 and other
      aggregating agents by stimulating a calcium extrusion pump.

PMID- 4374889
TI  - Are viruses important in carcinogenesis?
AB  - The role of viruses in the etiology of animal cancers is fairly certain.
      Information derived under both natural and experimental conditions supports the
      concept that either DNA- or RNA-containing viruses can fulfill this function. The
      DNA-containing herpesviruses, especially the Epstein-Barr virus, are currently
      the primary objects of intense investigation concerning their role in human
      cancer. This article will focus on the properties of counterpart herpesviruses in
      lower animals as well as the human virus candidates with an assessment of the
      observations concerning their oncogenic potential.

PMID- 4374893
TI  - [Role of cytomegalovirus infection in the pathology of the fetus, newborn and the
      mother (literature survey)].

PMID- 4374894
TI  - Acute cyanide poisoning.

PMID- 4374895
TI  - [Use of Polydexa ear drops in E.N.T].

PMID- 4374896
TI  - [Ophthalmic herpes zoster: current data].

PMID- 4374897
TI  - [The use of injectable Premarin in oral surgery].

PMID- 4374898
TI  - Excretion of individual adrenocortical steroids in obese children.

PMID- 4374899
TI  - Infantile rickets with server proximal renal tubular acidosis, responsive to
      vitamin D.

PMID- 4374900
TI  - Thyrotoxic myopathy.

PMID- 4374901
TI  - Nuclear and cytoplasmic inclusions in normal human epidermis.

PMID- 4374902
TI  - The chemotherapy of rodent malaria. XX. Autophagic vacuole formation in
      Plasmodium berghei in vitro.

PMID- 4374903
TI  - Ultrastructure of the bloodstream forms of an avian trypanosome Trypanosoma
      bouffardi.

PMID- 4374904
TI  - [Clinical, histochemical and ultrastructural data in a case of Verner-Morrison
      syndrome (WDHA)].

PMID- 4374905
TI  - [A new infinite cell line, MaTu, of human mammary tumor-cells (author's transl)].

PMID- 4374906
TI  - [Natural history of chorionepitheliomas(author's transl)].

PMID- 4374907
TI  - Nuclear inclusions in lutein cells of pregnant rats.

PMID- 4374908
TI  - Electron microscopic studies on dog testicular interstitial cells.

PMID- 4374909
TI  - [Cell susceptibility to FMDV by cell monolayers previously exposed to inactivated
      Sendai virus (author's transl)].

PMID- 4374910
TI  - [Effect of insecticides on metabolism and susceptibility of IB-RS-2 cells to foot
      and-mouth disease virus (author's transl)].

PMID- 4374911
TI  - [Dyscephalia, muco-synechial conjunctivitis and abnormalities of the limbs].

PMID- 4374912
TI  - [Crystalline bodies in the orbicular muscle sarcoplasm of the aged].

PMID- 4374913
TI  - The effects of alizarin red S on weight gain and skull growth in the rat.

PMID- 4374914
TI  - The chemical composition and some structural features of the principal salivary
      glycoprotein isolated from human mixed saliva.

PMID- 4374915
TI  - Use of specifically labelled sucrose for the quantitative assay of levansucrase
      activity.

PMID- 4374916
TI  - Adenoid cystic carcinoma of the maxilla.

PMID- 4374917
TI  - Refractile granular inclusions in a temperature-sensitive mutant of Escherichia
      coli K-12.

PMID- 4374918
TI  - studies of plasma bradykininases using radiolabelled substrates.

PMID- 4374919
TI  - Diabetes mellitus--a membrane receptor defect.

PMID- 4374920
TI  - Morphological development of the lung: a review.

PMID- 4374921
TI  - Equine herpesviruses. 5. Epizootiology of slowly cytopathic viruses in foals.

PMID- 4374922
TI  - The prevalence of antibodies to adenoviruses in horses from queensland and New
      South Wales.

PMID- 4374923
TI  - Mammary and extramammary Paget's disease.

PMID- 4374924
TI  - The mode of action of steroid hormones: some recent findings.

PMID- 4374926
TI  - Endocrine control of spermatogenesis.

PMID- 4374925
TI  - Progesterone-Progestin receptors.

PMID- 4374928
TI  - Protein synthesis machinery in growing oocytes of mice.

PMID- 4374927
TI  - Mechanism of action of luteinizing hormone-releasing hormone.

PMID- 4374929
TI  - The ultrastructure of Malignant Synovioma.

PMID- 4374930
TI  - Leaf peroxidase activities in tomato mutants affecting plant morphology.

PMID- 4374931
TI  - The interaction of alpha2-macroglobulin with proteinases. Binding and inhibition
      of mammalian collagenases and other metal proteinases.
AB  - 1. Experiments were performed to determine whether the specific collagenases and
      other metal proteinases are bound and inhibited by alpha(2)-macroglobulin, as are
      endopeptidases of other classes. 2. A specific collagenase from rabbit synovial
      cells was inhibited by human serum. The inhibition could be attributed entirely
      to alpha(2)-macroglobulin; alpha(1)-trypsin inhibitor was not inhibitory.
      alpha(2)-Macroglobulin presaturated with trypsin or cathepsin B1 did not inhibit
      collagenase, and pretreatment of alpha(2)-macroglobulin with collagenase
      prevented subsequent reaction with trypsin. The binding of collagenase by
      alpha(2)-macroglobulin was not reversible in gel chromatography. 3. The
      collagenolytic activity of several rheumatoid synovial fluids was completely
      inhibited by incubation of the fluids with alpha(2)-macroglobulin. 4. The
      collagenase of human polymorphonuclear-leucocyte granules showed time-dependent
      inhibition by alpha(2)-macroglobulin. 5. The collagenolytic metal proteinase of
      Crotalus atrox venom was inhibited by alpha(2)-macroglobulin. 6. The collagenase
      of Clostridium histolyticum was bound by alpha(2)-macroglobulin, and inhibited
      more strongly with respect to collagen than with respect to a peptide substrate.
      7. Thermolysin, the metal proteinase of Bacillus thermoproteolyticus, was bound
      and inhibited by alpha(2)-macroglobulin. 8. It was shown by polyacrylamidegel
      electrophoresis of reduced alpha(2)-macroglobulin in the presence of sodium
      dodecyl sulphate that synovial-cell collagenase, clostridial collagenase and
      thermolysin cleave the quarter subunit of alpha(2)-macroglobulin near its mid
      point, as do serine proteinases. 9. The results are discussed in relation to
      previous work, and it is concluded that the characteristics of interaction of the
      metal proteinases with alpha(2)-macroglobulin are the same as those of other
      proteinases.

PMID- 4374932
TI  - Identification of N-acetyl-4-O-acetylneuraminyl-lactose in Echidna milk.
AB  - The identity of a novel form of sialyl-lactose found in milk of the echidna
      (Tachyglossus aculeatus) was investigated. The sialyl-lactose yielded equimolar
      amounts of N-acetylneuraminic acid and lactose during mild acid hydrolysis but
      was resistant to the action of a bacterial neuraminidase. A viral neuraminidase
      hydrolysed it to lactose plus a form of sialic acid that reacted positively with
      thiobarbituric acid reagent but whose chromatographic mobility was greater than
      that of N-acetylneuraminic acid. Treatment with alkali converted the sialyl
      lactose into a substance with the same chromatographic mobility as N
      acetylneuraminyl-(2-->3)-lactose and made it susceptible to the action of
      bacterial neuraminidase. The sialyl-lactose contained one mol of ester
      (identified as acetyl), and released one mol of formaldehyde during periodate
      oxidation, per mol of sialic acid. It did not contain N-glycollylneuraminic acid.
      These results indicate that the sialyl-lactose is N-acetyl-4-O-acetylneuraminyl
      (2-->3)-lactose. Echidna milk contained, in addition, a small amount of N
      acetylneuraminyl-(2-->3)-lactose.

PMID- 4374933
TI  - Biospecific affinity chromatography of an adenosine 3':5'-cyclic monophosphate
      stimulated protein kinase (protamine kinase from trout testis) by using
      immobilized adenine nucleotides.
AB  - 1. Two adenine nucleotides, 8-(6-aminohexyl)aminoadenosine 3':5'-cyclic
      monophosphate and 8-(6-aminohexyl)amino-AMP, were synthesized. Their structures
      were established in particular by using mass spectroscopy. 2. Free cyclic AMP and
      8-(6-aminohexyl)amino cyclic AMP both stimulate protamine kinase activity at low
      concentrations, but are inhibitory at concentrations above 0.1mm. AMP is an
      inhibitor of enzymic activity, whereas neither 8-(6-aminohexyl)amino-AMP nor the
      earlier synthesized N(6)-(6-aminohexyl)-AMP is inhibitory. 3. The nucleotides
      were coupled to Sepharose 4B and used for biospecific chromatography of partially
      purified protamine kinase. Enzyme applied at high buffer concentrations to the
      cyclic AMP-Sepharose material was retarded and thereby purified tenfold. At low
      buffer concentrations the enzyme was adsorbed to the affinity material, and was
      subsequently released by a pulse of the inhibitor AMP, yielding a 50-100-fold
      purification. Enzyme applied to immobilized 8-(6-aminohexyl)amino-AMP or N(6)-(6
      aminohexyl)-AMP was eluted together with the main protein peak in the void
      volume. 4. Protamine kinase eluted from 8-(6-aminohexyl)amino cyclic AMP
      Sepharose was no longer activated by cyclic AMP. Results from sucrose gradient
      centrifugation suggest that a dissociation of the enzyme took place on the
      immobilized nucleotide. 5. Further information on the mass spectroscopy has been
      deposited as Supplementary Publication SUP 50026 at the British Library (Lending
      Division) (formerly the National Lending Library for Science and Technology),
      Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies may be obtained on the terms
      given in Biochem. J. (1973) 131, 5.

PMID- 4374934
TI  - The purification and amino acid sequence of cytochrome C-552 from Euglena
      gracilis.
AB  - Cytochrome c-552 from Euglena gracilis was purified and the amino acid sequence
      determined. The protein is a single peptide chain of 87 residues with the haem
      prosthetic group bound through two thioether linkages to two cysteine residues
      near the amino-terminal region. The amino acid sequence shows some similarities
      to mitochondrial cytochrome c and to two prokaryote c-type cytochromes. The
      sequence, taken with the known characteristics of cytochrome c-552, indicates
      that it is an f-type cytochrome. The possible functional and evolutionary
      significance of these features in common is discussed. Detailed evidence for the
      amino acid sequence of Euglena cytochrome f has been deposited as Supplementary
      Publication SUP 50027 at the British Library, Lending Division (formerly the
      National Lending Library for Science and Technology), Boston Spa, Yorks. LS23
      7QB, U.K., from whom copies can be obtained on the terms indicated in Biochem. J.
      (1973) 131, 5.

PMID- 4374935
TI  - Hepatic drug hydroxylation and lipid peroxidation in riboflavin-deficient rats.
AB  - The effect of riboflavin deficiency and phenobarbital pretreatment on drug
      hydroxylation and lipid peroxidation was investigated. A significant decrease in
      aniline and acetanilide hydroxylation as well as NADPH-linked and ascorbate
      induced lipid peroxidation was observed during 4- and 7-week riboflavin
      deficiency in both adult male and adult female rats. The drug-hydroxylation and
      lipid-peroxidation activities were further lowered with the increase in
      riboflavin deficiency. The phenobarbital pretreatment induced aniline and
      acetanilide hydroxylase activity even in riboflavin-deficient animals. Drug
      hydroxylation inhibits lipid peroxidation in both deficient and normal rats. The
      administration of riboflavin was followed by a significant increase in drug
      hydroxylation and lipid peroxidation.

PMID- 4374936
TI  - The concentration and control of cytoplasmic free inorganic pyrophosphate in rat
      liver in vivo.
AB  - The concentration of cytoplasmic free pyrophosphate was calculated in freeze
      clamped livers of rats from the measured concentration of reactants and K(eq.) of
      the UDP-glucose pyrophosphorylase reaction (UDP-alpha-d-glucose 1-phosphate
      uridylyltransferase, EC 2.7.7.9). The K(eq.) of the UDP-glucose pyrophosphorylase
      reaction was redetermined at 38 degrees C, pH7.0, I=0.25mol/l and free
      [Mg(2+)]=1mm, and was 4.55 in the direction of glucose 1-phosphate formation. The
      activity of UDP-glucose pyrophosphorylase in rat liver was between 46 and 58mumol
      of glucose 1-phosphate formed/min per g fresh wt. in the four dietary conditions
      studied. A fluorimetric assay with enzymic cycling was developed for the
      measurement of glucose 1-phosphate in HClO(4) extracts of rat liver. The
      calculated free cytoplasmic PP(i) concentration in nmol/g fresh wt. of liver was
      2.3+/-0.3 in starved, 3.8+/-0.4 in fed, 4.9+/-0.6 in meal-fed and 5.2+/-0.4 in
      sucrose-re-fed animals. These values agree well with recently determined direct
      measurements of total PP(i) in rat liver and suggest that there is not a large
      amount of bound or metabolically inert PP(i) in rat liver. The cytoplasmic
      [ATP]/[AMP][PP(i)] ratio is 10(3) times the cytoplasmic [ATP]/[ADP][P(i)] ratio
      and varies differently with dietary state. The reaction PP(i)+H(2)O-->2P(i)
      catalysed by inorganic pyrophosphatase (EC 3.6.1.1) does not attain near
      equilibrium in vivo. PP(i) should be considered as one of the group of small
      inorganic ions which is metabolically active and capable of exerting a
      controlling function in a number of important metabolic reactions.

PMID- 4374937
TI  - The biochemistry of virus-induced cell fusion. Changes in membrane integrity.
AB  - 1. Phospholipids prelabelled with [(14)C]acetate, [(32)P]phosphate, [(3)H]- or
      [(14)C]-choline or [(3)H]inositol are not significantly degraded during fusion of
      Lettree cells mediated by Sendai virus, nor are carbohydrates prelabelled with
      [(3)H]fucose, [(14)C]galactose or [(3)H]glucosamine. Less than 1nmol of
      lysophosphatidylcholine/10(7) cells is formed during fusion. Diethyl p
      nitrophenyl phosphate, which inhibits phospholipase A by more than 95% has no
      effect on fusion. It is concluded that none of the events leading to cell fusion
      is accompanied by significant turnover of phospholipids or other membrane
      components. 2. Intracellular K(+) leaks out during virally mediated cell fusion;
      the loss is not as extensive as that of intracellularly accumulated choline or
      deoxyglucose. Movement of Ca(2+) into or out of cells could not be detected. 3.
      At concentrations of Lettree cells insufficient to be agglutinated by virus,
      intracellularly accumulated choline and deoxyglucose leak out. Agglutination
      caused by concanavalin A does not result in leakage of intracellular metabolites.
      4. P815Y cells, which agglutinate but do not fuse in the presence of virus, show
      leakage of intracellularly accumulated metabolites. The extent of leakage does
      not alter during the G(1) and S periods of the cell cycle. 5. Leakage is
      inhibited by Ca(2+), but is unaffected by EDTA. 6. It is concluded that the
      interaction of Sendai virus with mammalian cells causes a weakening of membrane
      integrity so that intracellular metabolites leak out. Such destabilization may
      facilitate viral entry and is therefore an interesting system for further
      biochemical studies.

PMID- 4374938
TI  - Requirement for adenosine triphosphate for stimulation in vitro of ox growth
      hormone release.
AB  - Rotenone, carbonyl cyanide chloromethoxyphenylhydrazone and 2,4-dinitrophenol
      cause parallel falls in ox pituitary ATP content and growth-hormone release in
      the presence of 65mm-K(+). Carbonyl cyanide chloromethoxyphenylhydrazone
      (0.4mug/ml) prevented the rise in growth-hormone release, but not the rise in
      3':5'-cyclic AMP content after addition of prostaglandin E(2) (1mug/ml). The rate
      of hormone release from unstimulated slices and from slices in the presence of
      Ba(2+) at 2.3 or 6.9mm was proportional to the ATP content of the slices.
      Carbonyl cyanide chloromethoxyphenylhydrazone at concentrations that inhibited
      release in the presence of the three secretagogues did not alter the pituitary
      contents of Na(+), K(+) or Ca(2+). The implications of these observations are
      discussed in terms of the mechanism of stimulus-secretion coupling.

PMID- 4374939
TI  - Cytotoxic effects of streptozotocin and N-nitrosomethylurea on the pancreatic B
      cells with special regard to the role of nicotinamide-adenine dinucleotide.
AB  - The effects on the pancreatic B cell of streptozotocin and its aglucone
      derivative N-nitrosomethylurea were investigated in obese-hyperglycaemic mice and
      their lean littermates. Both streptozotocin and N-nitrosomethylurea were found to
      be B-cytotoxic although N-nitrosomethylurea produced less islet damage. Both
      substances decreased the concentrations of NAD(+) in the islet cells to about 10%
      of the control values within 2h after injection. This NAD(+) depletion was
      prevented by injection of nicotinamide 10min after the administration of
      streptozotocin or N-nitrosomethylurea. In islets taken from animals 10min after
      injection of streptozotocin or N-nitrosomethylurea there was no stimulatory
      effect of glucose on the respiration or insulin release and the oxidation of
      glucose was markedly decreased. Addition of nicotinamide (10mm) to the incubated
      islets restored glucose stimulation of both the oxygen consumption and insulin
      release. It is concluded that islet NAD(+) depletion is probably important for
      the B-cytotoxin action of N-nitrosomethylurea and streptozotocin. The glucose
      residue in the streptozotocin molecule may potentiate the B-cytotoxic action of
      this drug in mice.

PMID- 4374940
TI  - High-affinity binding of oestradiol-17beta by cytosols from testis interstitial
      tissue, pituitary, adrenal, liver and accessory sex glands of the male rat.
AB  - The specificity of the binding of oestradiol-17beta by cytoplasmic fractions of
      several tissues of the male rat was investigated. 1. Agar-gel electrophoresis,
      Sephadex chromatography, adsorption by dextran-coated charcoal and sucrose
      gradient centrifugation were used to estimate the binding capacity and
      specificity. The four different methods all gave similar results for the capacity
      of the specific oestradiol-17beta-binding macromolecules in the testis. 2. The
      presence of a specific saturable binding protein with a sedimentation coefficient
      of 8S was demonstrated in liver, adrenal, pituitary, prostate, epididymis and
      testis interstitial tissue. The highest concentration of oestradiol-17beta
      binding macromolecules was found in testis interstitial tissue (0.12pmol/mg of
      protein) and in the pituitary (0.075pmol/mg of protein). 3. The oestradiol-17beta
      receptor in the testis cytosol showed the characteristics of a protein with
      respect to Pronase treatment and temperature sensitivity. In competition
      experiments with different steroids the receptor showed a high affinity for
      oestradiol-17beta, a moderate affinity for diethylstilboestrol and oestradiol
      17alpha and a low affinity for oestrone, oestriol, testosterone and 5alpha
      dihydrotestosterone (17beta-hydroxy-5alpha-androstan-3-one). 4. The wide
      distribution of oestradiol-17beta receptors in the male rat is in apparent
      contradiction to the current concept of the specificity of steroid-hormone
      action. Further research is required to investigate a possible physiological
      meaning of the presence of specific receptors in the different tissues.

PMID- 4374941
TI  - The mechanism of intestinal absorption of phosphatidylcholine in rats.
AB  - 1. The mechanism of absorption of phosphatidylcholine was studied in rats by
      injecting into the intestine phosphatidylcholine specifically labelled either in
      the fatty acid or in the glycerol moiety or with (32)P, when considerable amounts
      of 1-acyl-lysophosphatidylcholine were found in the intestinal lumen. 2
      ([(14)C]Acyl)phosphatidylcholine gave markedly more radioactive unesterified
      fatty acids in the lumen, compared with the 1-([(14)C]acyl) derivative. Some of
      the radioactivity from either the fatty acid or the glycerol moiety of the
      injected phosphatidylcholine appeared in the mucosal triacylglycerols. 2.
      Injection of (32)P-labelled phosphatidylcholine or (32)P-labelled
      lysophosphatidylcholine led to the appearance of radioactive
      glycerylphosphorylcholine, glycerophosphate and P(i) in the mucosa. 3. Rat mucosa
      was found to contain a highly active glycerylphosphorylcholine diesterase. 4. It
      was concluded that the dietary phosphatidylcholine is hydrolysed in the
      intestinal lumen by the pancreatic phospholipase A to 1
      acylglycerylphosphorylcholine, which on entering the mucosal cell is partly
      reacylated to phosphatidylcholine, and the rest is further hydrolysed to
      glycerylphosphorylcholine, glycerophosphate, glycerol and P(i). The fatty acids
      and glycerophosphate are then reassembled to give triacylglycerols via the
      Kennedy (1961) pathway.

PMID- 4374944
TI  - The metabolism of phosphatidylcholine in brain tissue.

PMID- 4374942
TI  - Involvement of binding lipoproteins in the absorption and transport of alpha
      tocopherol in the rat.
AB  - 1. Specific lipoproteins binding alpha-tocopherol but not its known metabolites
      have been isolated and identified from cytosol of rat intestinal mucosa and from
      serum. 2. A timestudy of the appearance of the orally administered alpha
      [(3)H]tocopherol with these lipoproteins indicates that very-low-density
      lipoprotein of serum acts as a carrier of the vitamin. 3. The involvement of the
      mucosal lipoprotein in the absorption of the vitamin from the intestine has been
      inferred from observations on the amounts of alpha-tocopherol in serum of orotic
      acid-fed rats where release of lipoproteins from the liver to serum is completely
      inhibited. A considerable decrease in the association of alpha-tocopherol with
      serum very-low-density lipoprotein under this condition is interpreted to mean
      that serum lipoproteins are limiting factors for the transport of the vitamin
      across the intestine and that this is possibly effected by exchange of alpha
      tocopherol between serum very-low-density lipoprotein and mucosal lipoprotein.

PMID- 4374943
TI  - Effects of alpha-amanitin on the stimulation of prostatic ribonucleic acid
      polymerase by prostatic steroid-protein receptor complexes.
AB  - Stimulation of prostatic RNA polymerase in vitro by prostatic 17beta-hydroxy
      5alpha-androstan-3-one (5alpha-dihydrotestosterone)-receptor complexes has been
      previously reported. By use of the selective inhibitor, alpha-amanitin, we have
      shown that both nucleolar and extranucleolar RNA polymerase activities may be
      stimulated, but stimulation is abolished at high ionic strength.

PMID- 4374945
TI  - Cell-free biosynthesis of polyprenyl derivatives of p-hydroxybenzoic acid in
      mammalian and bacterial systems.

PMID- 4374946
TI  - Inositol lipid metabolism and the cell membrane.

PMID- 4374947
TI  - The role of lipids in membrane structure.

PMID- 4374948
TI  - Biosynthesis of unsaturated fatty acids by higher plant systems.

PMID- 4374949
TI  - Cellular control of the uptake, storage and release of noradrenaline in
      sympathetic nerves.

PMID- 4374950
TI  - The influence of nerve-impulse flow on the synthesis and metabolism of 5
      hydroxytryptamine in the central nervous system.

PMID- 4374951
TI  - The storage and release of acetylcholine by cholinergic nerve terminals: recent
      results with non-mammalian preparations.

PMID- 4374952
TI  - Adenosine 3':5'-cyclic monophosphate as a mediator in the action of neurohumoral
      agents.

PMID- 4374953
TI  - Inhibition of various cyclic AMP phosphodiesterases by pentifylline and
      theophylline.

PMID- 4374954
TI  - Effect of allopurinol on the synthesis of corticosterone in rat adrenals in
      vitro.

PMID- 4374955
TI  - Wet fallout of sulfurous pollutants emitted from a city during rain or snow.

PMID- 4374957
TI  - [Phytase activity of the intestinal mucosa of the rat].

PMID- 4374956
TI  - [Action of dibutyryl cyclic AMP glucosamine salt on oxidative phosphorylation of
      hypertrophic heart sarcosomes].

PMID- 4374958
TI  - [Ineffectiveness of theophylline in potentiating the blood cortisol response to
      intravenous injection of cyclic dibutyl adenosine-3,5-monophosphate in humans].

PMID- 4374959
TI  - [Evaluation of the initial blood cortisol response after duplicate and closely
      repeated intravenous stimulation with synthetic beta-1-24 corticotropin].

PMID- 4374960
TI  - [Thalamic transfer of the efferent activity of the hippocampus in the cat].

PMID- 4374961
TI  - [Action of silicon on lipid metabolism].

PMID- 4374962
TI  - An unusual mandibular first molar. A case report.

PMID- 4374964
TI  - Ectopic production of human chorionic gonadotrophin by human breast tumours.
AB  - The incidence of tumours ectopically producing the human chorionic gonadotrophins
      was studied in patients with breast cancer. Specific radioimmunoassay of subunits
      of HCG was utilized. Nine out of 65 patients with carcinoma of breast showed the
      presence of circulating HCG. Patients with other pathological conditions of
      breast tissue did not show any evidence of circulating HCG.

PMID- 4374965
TI  - [Application of gas chromatography to the determination of proline and
      hydroxyproline, incorporated during collagen biosynthesis].

PMID- 4374963
TI  - A tumour cell aggregation promoting substance from rat ascites hepatoma cells.
AB  - A substance capable of promoting tumour cell aggregation was released from rat
      ascites hepatoma cell (possibly from the cell surface) kept in Hanks' balanced
      salt solution (free of calcium and magnesium) in the cold, and then partially
      purified by chromatography with DEAE-Sephadex and gel filtration with Bio-gel.
      The thermostable substance seemed to be a glycoprotein and its molecular weight
      was about 72,000 when measured by gel filtration on Sephadex G-200. It had no
      proteolytic activity. The material was clearly effective for rat ascites hepatoma
      cells as well as SV40 transformed cells, but less effective for Chang's cells and
      apparently ineffective for normal rat liver cells and red blood cells. The action
      of this material was more potent than that of Jack bean concanavalin A when
      assayed for aggregation of SV40 transformed cells. Its effect was not influenced
      by concanavalin A inhibitors such as alpha-methyl-D-glucopyranoside, N-acetyl-D
      glucosamine and D-glucose.

PMID- 4374966
TI  - Dephosphorylation of rat liver ribosomal proteins by a phosphoprotein
      phosphatase.

PMID- 4374967
TI  - [Isolation and characterization of yeast NADH C-nitrosoreductase].

PMID- 4374968
TI  - Beef pancreas tryptophanyl-tRNA synthetase. Order of substrate binding in ATP-(32
      P)-pyrophosphate exchange reaction.

PMID- 4374970
TI  - [Polar lipids from Pelvetia canaliculata (L) Dech. and Thur., Fucus vesiculosus
      L. and Fucus servatus L].

PMID- 4374969
TI  - Intramitochondrial intermembranal large amplitude protein movements. I. A
      possible novel aspect of membrane fluidity.

PMID- 4374971
TI  - Research of specific constraints in pair association of amino acids.

PMID- 4374973
TI  - [The demyelinating effect of immune lymphocytes in nerve tissue cultures].

PMID- 4374972
TI  - [Primary structure of tRNA Arg/III of brewer's yeast. 1. Complete hydrolysis by
      pancreatic and T1 ribonucleases].

PMID- 4374975
TI  - [The hypothalano-adenohypophyseal-adrenal neurosecretory system under
      hyperthermic conditions].

PMID- 4374974
TI  - [Inactivation of the biological action of estrogens and growth hormone by
      antibodies to the hormonally inactive conjugate of human somatotriopin and
      estrone].

PMID- 4374976
TI  - [Dynamics of blood catalase and peroxidase activity of rabbits during prolonged
      cholesterol feeding].

PMID- 4374977
TI  - [Kinetic patterns in the growth of transplantable hepatoma with different degrees
      of differentiation].

PMID- 4374978
TI  - [Distribution of a carcinogen-binding protein in primary liver tumors induced by
      3-methyl-4-dimethylaminoazobenzene in rats].

PMID- 4374979
TI  - [The effect of neuromediators on soluble thiol levels in brain tissue].

PMID- 4374980
TI  - [Isolation of an estradiol-binding system from guinea pig uterus].

PMID- 4374981
TI  - [Binding of concanavallin A by normal and tumor cells].

PMID- 4374983
TI  - [The embryotoxic and transplacental blastomogenic effect of symmetrical
      dialkylnitrosamines on the progeny of rats].

PMID- 4374982
TI  - [The influence of hypothermia on the development of neurogenic pulmonary edema].

PMID- 4374984
TI  - [Kinetics of rat thymus and ascitic hepatoma DNA reassociation].

PMID- 4374985
TI  - [The possible influence of several dispersants (trypsin, EDTA) on the cellular
      composition of Seidel's hepatoma].

PMID- 4374986
TI  - Release of prostaglandins from the rabbit perfused kidney: effects of
      vasoconstrictors.
AB  - 1 The rat stomach strip was used to assay prostaglandin E(2)-like material
      released by a rabbit isolated kidney perfused with Krebs solution.2 Doses of
      noradrenaline and angiotensin II producing similar vasoconstrictor effects
      released equivalent amounts of prostaglandins from the kidney.3 8-Leu-angiotensin
      II, a specific inhibitor of the natural octapeptide, blocked the action of
      angiotensin II on perfusion pressure and the release of prostaglandins, while the
      action of noradrenaline on both parameters was unaffected.4 Indomethacin, a
      specific inhibitor of prostaglandin biosynthesis, blocked the effects of both
      vasoconstrictors on prostaglandin release while their action on perfusion
      pressure was significantly enhanced.5 In the kidney effluent, amounts of
      prostaglandin E(2)-like material increased linearly with the rise in perfusion
      pressure induced by increasing doses of angiotensin II. These results indicate
      that prostaglandin output from the isolated kidney follows the rise in perfusion
      pressure.

PMID- 4374987
TI  - Dissociation of 5-hydroxytryptamine effects on myocardial contractility and
      cyclic AMP accumulation.
AB  - 1 5-Hydroxytryptamine increased the contractility of the isolated rat atrium and
      produced a small rise in cyclic 3',5'-adenosine monophosphate (cyclic AMP)
      accumulation in rat heart slices. These effects were similar to those of
      tyramine.2 Incubation with phenoxybenzamine prevented the inotropic effect of 5
      hydroxytryptamine but did not inhibit the rise in cyclic AMP accumulation.3 A
      single injection of reserpine 24 h before the experiment did not inhibit the
      inotropic effect of 5-hydroxytryptamine but prevented the rise in cyclic AMP
      accumulation.4 It is concluded that in the rat 5-hydroxytryptamine increases
      cardiac contractility chiefly by a direct effect which is blocked by
      phenoxybenzamine, whereas it increases myocardial cyclic AMP accumulation
      indirectly by releasing endogenous catecholamines. Cardiac contractility may thus
      be increased without a rise in cyclic AMP accumulation, and cyclic AMP
      accumulation may be increased without a rise in contractility.

PMID- 4374989
TI  - The microbiology and sensory evaluation of pheasants hung at 5, 10 and 15 degrees
      C.

PMID- 4374988
TI  - Sexually-transmitted diseases in animals.

PMID- 4374990
TI  - [Kinetic study on the renin-angiotensin system in the presence of a beta
      blockader: pindolol].

PMID- 4374991
TI  - [State of vigilance of adult baboons papio papio as studied by telemetry in an
      African environment].

PMID- 4374992
TI  - The effect of phenytoin on parathyroid extract and 25-hydroxycholecalciferol
      induced bone resorption: adenosine 3, 5 cyclic monophosphate production.

PMID- 4374995
TI  - The conversion of cytochrome oxidase to an inactive form of the enzyme by water
      dialysis.

PMID- 4374993
TI  - Studies on dentinogenesis in the rat. The interaction between lead-pyrophosphate
      solutions and dentinal globules.

PMID- 4374994
TI  - Histochemical studies on alkaline phosphatases in mineralizing oral tissues in
      the mouse.

PMID- 4374996
TI  - Phosphoribosyl pyrophosphate degradation in human tissues.

PMID- 4374997
TI  - Inhibition of Rauscher leukemia virus and avian myeloblastosis virus DNA
      polymerases by tilorone (NSC-143969) and its analogs.

PMID- 4374998
TI  - Comparison of postoperative irradiation alone and in combination with BCNU (NSC
      409962) in the management of malignant gliomas.

PMID- 4374999
TI  - Phosphoriboxyl transferase in colon tumor and normal mucosa as an aid in adjuvant
      chemotherapy with 5-fluorouracil (NSC-19893).

PMID- 4375000
TI  - The goldfish pituitary. I. Cytology.

PMID- 4375001
TI  - Cell autolysis and deletion in the planarian Polycelis tenuis Iijima.

PMID- 4375002
TI  - The ACTH-interrenal axis in the freshwater stickleback, Gasterosteus aculeatus
      form leiurus.

PMID- 4375003
TI  - Fine structure and function of the alimentary epithelium in Artemia salina
      nauplii.

PMID- 4375004
TI  - Ultracytochemistry of the lung of Polypterus ornatipinnis.

PMID- 4375005
TI  - Coronet cells in the neurohypophysis of Mugil capito Cuvier and Valenciennes
      (Teleostei) from a hypersaline lagoon.

PMID- 4375006
TI  - Ultrastructural study of arterio-venous anastomoses in gill filaments of Tilapia
      mossambica.

PMID- 4375007
TI  - Electron microscopic autoradiography of Ca-45 during dentinogenesis.

PMID- 4375009
TI  - [To problems of nosocomial infections due to Adenoviruses (author's transl)].

PMID- 4375010
TI  - [Clinical course of papillomatosis of the larynx in children].

PMID- 4375008
TI  - The hypothalamo-hypophysial system of hypophysectomized rats. I. Ultrastructure
      of nerve fibres in "intact" and dehydrated animals.

PMID- 4375011
TI  - [Mechanism of the inoculum effect (population effect) in Pseudomonas aeruginosa
      on media with added polymyxin].

PMID- 4375012
TI  - [Determination of alpha-fetoprotein. Comparison between the reagent used in
      hemagglutination reaction and alpha-1-fetoprotein "Kowa Reagent" used in single 
      radial immunodiffusion].

PMID- 4375013
TI  - Changes in plasma lipoprotein lipids in hypercholesterolaemic patients treated
      with the bile acid-sequestering resin, colestipol.

PMID- 4375014
TI  - The metabolism of low-density lipoprotein in a patient with familial
      hyperbetalipoproteinaemia.

PMID- 4375015
TI  - A new approach to estrogen-free contraception based on progesterone receptor
      blockage by mid-cycle administration of ethyl norgestrienone (R 2323).

PMID- 4375017
TI  - SQ 65,396: a non-sedative anxiolytic?

PMID- 4375016
TI  - Microbiological assay in quantitative histochemistry.

PMID- 4375018
TI  - Recent progress in studies of mouse type-C viruses.

PMID- 4375019
TI  - The biochemistry of icosahedral cytoplasmic deoxyviruses.

PMID- 4375020
TI  - [Increasing the rate of virus isolation in cases of cold with low-grade or no
      fever. A preliminary report of 70 cases].

PMID- 4375021
TI  - [Letter: Therapy of thyrotoxic crises].

PMID- 4375022
TI  - [Malignant neoplasms in children in Finland, 1953-70].

PMID- 4375023
TI  - [Senological report on breast cancers in situ].

PMID- 4375024
TI  - [Intra-galactophorous epithelial proliferations].

PMID- 4375025
TI  - [Surgery of noninfiltrating intraductal tumors of the breast].

PMID- 4375026
TI  - Mode of existence of corticosterone in adrenal cells with reference to storage
      and secretion.

PMID- 4375028
TI  - Phosphorylation of nuclear proteins fron bovine anterior pituitary gland induced
      by adenosine 3':5'-monophosphate.

PMID- 4375027
TI  - Effect of ACTH and dexamethasone on the rate of protein and RNA degradation in
      rat adrenal glands.

PMID- 4375030
TI  - The mechanism of inhibition of pig-plasma benzylamine oxidase by the copper
      chelating reagent cuprizone.

PMID- 4375029
TI  - The role of lysine and leucine binding on the catalytical and structural
      properties of aspartokinase III of Escherichia coli K 12.

PMID- 4375031
TI  - Effect of azide on some spectral and kinetic properties of pig-plasma benzylamine
      oxidase.

PMID- 4375032
TI  - Synthesis of ATP from ADP and inorganic phosphate at the myosin-subfragment 1
      active site.

PMID- 4375033
TI  - A high-molecular-weight protein component required for natural messenger
      translation in ascites tumor cells.

PMID- 4375034
TI  - Chemical studies on Shigella sonnei lipid A.

PMID- 4375035
TI  - Adenylate kinase of porcine heart.

PMID- 4375037
TI  - Effect of imipramine on the behavior of rat-liver mitochondria during
      centrifugation in a sucrose gradient.

PMID- 4375036
TI  - [Phospholipase C-induced release reaction in platelets (author's transl)].

PMID- 4375038
TI  - The covalently bound flavin of Chromatium cytochrome c552. 1. Evidence for
      cysteine thiohemiacetal at the 8 alpha position.

PMID- 4375039
TI  - Differences between the estradiol and testosterone receptors in rat uterus.

PMID- 4375040
TI  - Synthesis and properties of N6, C-8 and C-2 spin-labelled derivatives of
      adenosine cyclic 3':5'-monophosphate.

PMID- 4375042
TI  - The interaction of apoprotein from porcine high-density lipoprotein with
      dimyristoyl phosphatidylcholine.

PMID- 4375041
TI  - Studies on the metabolic effects induced in the rat by a high-fat diet. Control
      of glucose metabolism in adipose tissue of fed and fasted rats.

PMID- 4375043
TI  - The interaction of apoprotein from porcine high-density lipoprotein with
      dimyristoyl phosphatidylcholine. Electron spin resonance and fluorescent probe.
      studies.

PMID- 4375044
TI  - [Formation of heterotopic somatic inputs into the sensomotor region of the cat
      cortex].

PMID- 4375045
TI  - [Changes in the ultrastructure and bioelectrical activity of the Retzius cells of
      the medicinal leech during synaptic and direct stimulation].

PMID- 4375046
TI  - [The effect of ACTH on blood pressure in rats].

PMID- 4375047
TI  - [The effect of hippocampal stimulation on the neuronal activity of the reticular
      formation].

PMID- 4375048
TI  - [Manifestation of the paradoxical stage of sleep in neuronally isolated cat
      neocortex].

PMID- 4375049
TI  - [Cytogenetical studies on malignant tumors of epithelial and mesenchimal origin
      (author's transl)].

PMID- 4375050
TI  - Proceedings: Multiple forms of adenosine 3':5'-cyclic monophosphate
      phosphodiesterase in bovine corpus luteum.

PMID- 4375051
TI  - Proceedings: Partial purification and initial observations of molecular weights
      of luteal adenosine 3':5'-cyclic monophosphate-binding proteins.

PMID- 4375052
TI  - Proceedings: Adenosine 3':5'-cyclic monophosphate-binding proteins in rat corpus
      luteum.

PMID- 4375053
TI  - Proceedings: Rat luteal adenosine 3':5'-cyclic monophosphate-dependent protein
      kinase.

PMID- 4375054
TI  - Proceedings: The effect of an ovulatory dose of human chorionic gonadotrophin on
      preovulatory adenosine 3':5'-cyclic monophosphate concentrations in rabbit
      ovarian tissue.

PMID- 4375055
TI  - Proceedings: Variation in urinary adenosine 3':5'-cyclic monophosphate contend
      during the human menstrual cycle.

PMID- 4375056
TI  - Proceedings: Control of glycerokinase activity by sex hormones.

PMID- 4375057
TI  - Protein composition in developing human brain myelin.

PMID- 4375058
TI  - Cysteamine-induced duodenal ulcers: a new model to test antiulcer agents.

PMID- 4375059
TI  - Congenitally impaired hormone sensitivity of the adipose tissue of spontaneously
      diabetic mice, KK.  Validity of thrifty genotype in KK mice.

PMID- 4375061
TI  - The lipolytic system in adipose tissue of Toronto-KK and C57BL/KsJ diabetic mice.
      Adenylate cyclase, phosphodiesterase and protein kinase activities.

PMID- 4375060
TI  - Diabetes in the Toronto-KK hybrid mouse abnormalities in liver and pancreatic
      islets of Langerhans.

PMID- 4375062
TI  - Lipolysis and adenosine 3'5'-cyclic monophosphate in adipose tissue of the New
      Zealand obese mouse; the activities of adipose tissue adenyl cyclase and
      phosphodiesterase.

PMID- 4375064
TI  - Control of insulin secretion in the Egyptian sand rat ((Psammomys obesus).

PMID- 4375063
TI  - Evidence for decreased sensitivity to glucose of isolated islets from spiny mice.
      (Acomys cahirinus).

PMID- 4375066
TI  - ["Sinking" lipoprotein].

PMID- 4375065
TI  - [Characterization of the plaques formed by herpes simplex virus in various cell
      cultures, at various passages].

PMID- 4375067
TI  - [Limitations of the angiotensin II test for the recognition of angina pectoris
      (author's transl)].

PMID- 4375068
TI  - [Rachitism deficiencies. Epidemiologic and clinical aspects of 70 cases].

PMID- 4375069
TI  - Physiological studies of salmonella histidine operator-promoter mutants.
AB  - S. typhimurium hisO mutations are cis dominant and trans recessive and occur in a
      regulatory segment separate from but adjacent to the first structural gene of the
      histidine operon, hisG. Strains containing hisO mutations singly and in
      combination with other regulatory mutations were examined for their content of L
      histidinol phosphate phosphatase when grown on limiting and on excess L
      histidine. HisO mutations classed as "constitutive" (high enzyme levels) or as
      "promoter-like" (low enzyme levels) cause a variety of sub-phenotypes. A model is
      proposed that accounts for the phenotypes found as well as for the interspersion
      of constitutive and promoter-like mutations on the genetic map (Ely, Fankhauser
      and Hartman 1974). In this model we suggest that the his operator-promoter DNA is
      a functional unit that assumes alternate conformations including: (a) the classic
      linear duplex, active in transcription, and (b) a looped structure that is
      transcriptionally closed and susceptible to the binding of repressor.

PMID- 4375070
TI  - The clinical significance of immunological findings in Burkitt's lymphoma.
      (Epstein-Barr virus-associated antibodies/BCG treatment.

PMID- 4375071
TI  - Tumor virus RNAs tumor virus genes.

PMID- 4375072
TI  - DNA polymerases in lymphoid cells.

PMID- 4375073
TI  - Electron microscopic and cytochemic findings in Di-Guglielmo's syndrome and in
      other forms of leukemia.

PMID- 4375074
TI  - [Cytomegalic inclusion disease in children in the light of anatomoclinical
      studies].

PMID- 4375075
TI  - Histochemical studies on the gastric epithelium and glands in guinea pigs
      subjected to the action of a fungicide (Kaptan).

PMID- 4375077
TI  - [Xero-radiography of the skull (author's transl)].

PMID- 4375076
TI  - Histochemical studies on the liver of white rats at various intervals after
      transection of the vagus nerves.

PMID- 4375078
TI  - [Calcification and ossification of the falx cerebri (author's transl)].

PMID- 4375079
TI  - [Petrous bone tomography (experience with 98 examinations) (author's transl)].

PMID- 4375080
TI  - [The "multi-facetted" sacro-iliac findings--an early radiological finding in
      ankylosing spondylitis (author's transl)].

PMID- 4375081
TI  - [A rare fracture of the lumbar spine (marginal fracture of the fourth body and
      transverse process L.1 to 4) (author's transl)].

PMID- 4375083
TI  - [Resorptive giant cell granuloma and secondary hyper-parathyroidism (author's
      transl)].

PMID- 4375082
TI  - [Chondro-calcinosis (pseudo-gout) (author's transl)].

PMID- 4375084
TI  - [The radiological appearances caus-d by displacement of alloplastic materials of
      artificial hip joints (author's transl)].

PMID- 4375085
TI  - [Estimation of bone mineral content by means of 125I photon absorption
      measurements in normals (author's transl)].

PMID- 4375086
TI  - [Determination of bone mineral content from radiographs using digital data
      processing (author's transl)].

PMID- 4375087
TI  - [A method for the radiological-quantitative morpho-metry of spongey bone
      (author's transl)].

PMID- 4375088
TI  - [The haemodynamics of the angiographically demonstrable blood supply of cavernous
      angiomas in the soft tissues of the skull (author's transl)].

PMID- 4375089
TI  - [Unilaternal occlusion of the vertebral artery in a patient with assimilation of
      the atlas (author's transl)].

PMID- 4375090
TI  - [Transfemoral cerebral panarteriography for confirmation of cerebral death
      (author's transl)].

PMID- 4375092
TI  - [Radiotherapy in the treatment of primary cerebral tumours (results in 208
      patients and a review of the literature (author's transl)].

PMID- 4375091
TI  - [The pregnostic value of isotope cisternograms for shunt operations for
      communication hydrocephalus (author's transl)].

PMID- 4375094
TI  - [Perforation-like defect in the scapula with a deformity resembling a swallow
      tail at its lower part].

PMID- 4375093
TI  - [Case report on the varying concentration of bone-affiliated radionuclides].

PMID- 4375095
TI  - [Retroisthmic fissure in the lumbar spinal column].

PMID- 4375096
TI  - [Spontaneous repositioning of a severe mediolateral lumbar disk prolapse].

PMID- 4375097
TI  - [Methods of quantitative cine-cardio-angiography (author's transl)].

PMID- 4375098
TI  - [The determination of the ejection volume by means of cine radiography during
      left-sided ventriculography (author's transl)].

PMID- 4375099
TI  - [Selective coronarograms and coronary perfusion scintigram. II. Pathologic
      perfusion conditions in the circulation area of the right coronary artery].

PMID- 4375100
TI  - [Traumatic pneumo-pericardium (author's transl)].

PMID- 4375101
TI  - [Experience with a standardised technique for obtaining and interpreting chest
      radiographs (author's transl)].

PMID- 4375103
TI  - [Complete interruption of the aortic arch (author's transl)].

PMID- 4375102
TI  - [Perfusion abnormalities due to pneumonias -- scintigraphic differentiation from
      malignant lung changes (author's transl)].

PMID- 4375104
TI  - [Angiography in dissecting aneurysm of the aorta].

PMID- 4375105
TI  - [The arteriographic appearances of the hepatic arteries in portal hypertension
      (author's transl)].

PMID- 4375106
TI  - [Translumbar aortography with controlled catheter placement (author's transl)].

PMID- 4375107
TI  - [A comparison of the diagnostic accuracy of radiology and endoscopy in diseases
      of the stomach and duodenum (author's transl)].

PMID- 4375109
TI  - [Late stage of ulcerative colitis. A long-term radiologic follow-up].

PMID- 4375108
TI  - Abnormal duodenal loop in patients with sliding esophageal hiatal hernia --
      studies on intragastric pressure and gastrocolic reflex.

PMID- 4375110
TI  - [Malignant tumours of the biliary tree. Their demonstration by endoscopic
      retrograde cholangiogram (ERCG) (author's transl)].

PMID- 4375111
TI  - [Arteriovenous aneurysm of the lung as a first manifestation of Rendu-Osler's
      disease].

PMID- 4375112
TI  - [Angiographic demonstration of a traumatic aneurysm of renal artery following
      percutaneous kidney biopsy in a child].

PMID- 4375113
TI  - [Fibroleiomyomatosis of the stomach with secondary ossification].

PMID- 4375114
TI  - [Two cases of intracerebrally located foreign bodies (sewing needle)].

PMID- 4375116
TI  - Infrared spectra of DNA from normal & urethan-treated mice.

PMID- 4375117
TI  - Effect of exogenous 3',5'-cyclic adenosine monophosphate on the cell surface
      properties of the cellular slime mould, Dictyostelium discoideum.

PMID- 4375115
TI  - Enzyme electrophoresis on cellulose acetate gel. II. Zymogram patterns in man
      Chinese hamster somatic cell hybrids.

PMID- 4375118
TI  - Purification and properties of a new extracellular collagenase from Aspergillus
      sclerotiorum.

PMID- 4375119
TI  - Permeation of nucleotidic coenzymes into liver cells.

PMID- 4375120
TI  - The purification and new properties of the neutral proteinase in human semen.

PMID- 4375121
TI  - Endometrial biopsy using Gravlee Jet Washer and suction curette.

PMID- 4375122
TI  - Effects of microquantities of 5 alpha-dihydrotestosterone on the epididymis and
      accessory glands of the castrated rhesus monkey, Macaca mulatta.

PMID- 4375123
TI  - Effect of ageing on the volume, structure and total Leydig cell content of the
      human testis.

PMID- 4375124
TI  - Sex ratio in extrauterine pregnancies.

PMID- 4375125
TI  - Scanning electron microscopy of boar spermatozoa before and after frozen-thawed
      treatment.

PMID- 4375126
TI  - The influence of adoption on subsequent pregnancy in infertile marriage.

PMID- 4375128
TI  - Post tubal ligation menorrhagia and pelvic pain.

PMID- 4375127
TI  - The possible role of kinins in sperm motility.

PMID- 4375129
TI  - Clinical evaluation of a new low dose progestagen-only contraceptive containing
      cingestol.

PMID- 4375130
TI  - Survival of Entamoeba and related amoebae at low temperature-II. Viability of
      amoebae and cysts stored in liquid nitrogen.

PMID- 4375132
TI  - Isolation of avian nephroblastoma virus from avian myeloblastosis virus by the
      infectious DNA technique.

PMID- 4375133
TI  - Analysis of chromosomes of syrian hamster cells transformed with human
      cytomegalovirus.

PMID- 4375131
TI  - Observation of surface active lysosomes and other organelles in monoxenically
      cultivated trophozoites of ent amoeba histolytica and Ent amoeba coli.

PMID- 4375134
TI  - A systematic approach to sleep disorders: review and treatment.

PMID- 4375136
TI  - [Endoscopic retrograde cholangio-pancreatography in the diagnosis of biliary
      tract diseases].

PMID- 4375135
TI  - [News in American dermatology].

PMID- 4375137
TI  - Primary tumors and abnormal cysts of the liver in adults.

PMID- 4375138
TI  - [Combined drug-surgical treatment in primary and secondary liver tumors].

PMID- 4375139
TI  - [Surgical treatment of liver cell adenoma].

PMID- 4375140
TI  - [Indications for and results of Longmire's intrahepatic cholangiojejunostomy in
      proximal malignant stenosis of the hepatic duct].

PMID- 4375141
TI  - Different patterns of chromosome exchange induced by methyl-metanesulphonate and
      mitomycin C in human cells.

PMID- 4375142
TI  - Minor salivary glands of man: enzyme and mucosubstance histochemical studies.

PMID- 4375143
TI  - Salivary glands of the cat: a histochemical study.

PMID- 4375144
TI  - [Ultrastructural localization and subcellular distribution of inosine
      diphosphatase in the rat adrenal cortex (author's transl)].

PMID- 4375146
TI  - [Proceedings: Case report on the "onion-peel" lymphoma (=angiofollicular lymph
      node hyperplasia or Castleman's tumor), imitating a pleomorphous adenoma].

PMID- 4375145
TI  - Adenylate cyclase in an estradiol sensitive tissue: a cytochemical study.

PMID- 4375147
TI  - [Proceedings: Surgical therapy of salivary gland tumors].

PMID- 4375148
TI  - Fine structure of an edentate (Dasypus novemcinctus) male reproductive system:
      the epididymis.

PMID- 4375149
TI  - Proceedings: Human mast cell degranulation and vacuolation.

PMID- 4375151
TI  - Proceedings: Early Tasmanian morphology - new archaeological evidence.

PMID- 4375150
TI  - Proceedings: Small dense-cored vesicles in the cholinergic nerve terminals of the
      rat bladder.

PMID- 4375152
TI  - Trigeminal motor neuropathy.

PMID- 4375153
TI  - Neurological episodes following epidemic conjunctivitis.

PMID- 4375154
TI  - Inhibition of growth and DNA synthesis in cell cultures by cyclic AMP.

PMID- 4375155
TI  - Nucleolar development in the interphase of the cell cycle.

PMID- 4375156
TI  - Descriptive and quantitative study of ultrastructural changes in the apical
      meristem of mustard in transition to flowering. II. The cytoplasm, mitochondria
      and proplastids.